Sample records for identify research opportunities

  1. What do medical students understand by research and research skills? Identifying research opportunities within undergraduate projects.

    PubMed

    Murdoch-Eaton, Deborah; Drewery, Sarah; Elton, Sarah; Emmerson, Catherine; Marshall, Michelle; Smith, John A; Stark, Patsy; Whittle, Sue

    2010-01-01

    Undergraduate research exposure leads to increased recruitment into academic medicine, enhanced employability and improved postgraduate research productivity. Uptake of undergraduate research opportunities is reported to be disappointing, and little is known about how students perceive research. To investigate opportunities for undergraduate participation in research, recognition of such opportunities, and associated skills development. A mixed method approach, incorporating student focus and study groups, and documentary analysis at five UK medical schools. Undergraduates recognised the benefits of acquiring research skills, but identified practical difficulties and disadvantages of participating. Analysis of 905 projects in four main research skill areas - (1) research methods; (2) information gathering; (3) critical analysis and review; (4) data processing - indicated 52% of projects provided opportunities for students to develop one or more skills, only 13% offered development in all areas. In 17%, project descriptions provided insufficient information to determine opportunities. Supplied with information from a representative sample of projects (n = 80), there was little consensus in identifying skills among students or between students and researchers. Consensus improved dramatically following guidance on how to identify skills. Undergraduates recognise the benefits of research experience but need a realistic understanding of the research process. Opportunities for research skill development may not be obvious. Undergraduates require training to recognise the skills required for research and enhanced transparency in potential project outcomes.

  2. Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles

    PubMed Central

    2012-01-01

    This report is based on the Federation of American Societies for Experimental Biology’s symposium, “Engaging basic Scientists in Translational Research: Identifying Opportunities, Overcoming Obstacles,” held in Chevy Chase, MD, March 24–25, 2011. Meeting participants examined the benefits of engaging basic scientists in translational research, the challenges to their participation in translational research, and the roles that research institutions, funding organizations, professional societies, and scientific publishers can play to address these challenges. PMID:22500917

  3. Identifying Strategic Scientific Opportunities

    Cancer.gov

    As NCI's central scientific strategy office, CRS collaborates with the institute's divisions, offices, and centers to identify research opportunities to advance NCI's vision for the future of cancer research.

  4. Overview of energy-conservation research opportunities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hopp, W.J.; Hauser, S.G.; Hane, G.J.

    1981-12-01

    This document is a study of research opportunities that are important to developing advanced technologies for efficient energy use. The study's purpose is to describe a wide array of attractive technical areas from which specific research and development programs could be implemented. Research areas are presented for potential application in each of the major end-use sectors. The study develops and applies a systematic approach to identifying and screening applied energy conservation research opportunities. To broadly cover the energy end-use sectors, this study develops useful information relating to the areas where federally-funded applied research will most likely play an important rolemore » in promoting energy conservation. This study is not designed to produce a detailed agenda of specific recommended research activities. The general information presented allows uniform comparisons of disparate research areas and as such provides the basis for formulating a cost-effective, comprehensive federal-applied energy conservation research strategy. Chapter 2 discusses the various methodologies that have been used in the past to identify research opportunities and details the approach used here. In Chapters 3, 4, and 5 the methodology is applied to the buildings, transportation, and industrial end-use sectors and the opportunities for applied research in these sectors are discussed.Chapter 6 synthesizes the results of the previous three chapters to give a comprehensive picture of applied energy conservation research opportunities across all end-use sectors and presents the conclusions to the report.« less

  5. Using the Integrated Vehicle Health Management Research Test and Integration Plan Wiki to Identify Synergistic Test Opportunities

    NASA Technical Reports Server (NTRS)

    Koelfgen, Syri J.; Faber, James J.

    2010-01-01

    The National Aeronautics and Space Administration (NASA) and the aviation industry have recognized a need for developing a method to identify and combine resources to carry out research and testing more efficiently. The Integrated Vehicle Health Management (IVHM) Research Test and Integration Plan (RTIP) Wiki is a tool that is used to visualize, plan, and accomplish collaborative research and testing. Synergistic test opportunities are developed using the RTIP Wiki, and include potential common resource testing that combines assets and personnel from NASA, industry, academia, and other government agencies. A research scenario is linked to the appropriate IVHM milestones and resources detailed in the wiki, reviewed by the research team members, and integrated into a collaborative test strategy. The scenario is then implemented by creating a test plan when appropriate and the research is performed. The benefits of performing collaborative research and testing are achieving higher Technology Readiness Level (TRL) test opportunities with little or no additional cost, improved quality of research, and increased communication among researchers. In addition to a description of the method of creating these joint research scenarios, examples of the successful development and implementation of cooperative research using the IVHM RTIP Wiki are given.

  6. Comparative and cost-effectiveness research: Competencies, opportunities, and training for nurse scientists.

    PubMed

    Stone, Patricia W; Cohen, Catherine; Pincus, Harold Alan

    Comparative and cost-effectiveness research develops knowledge on the everyday effectiveness and value of treatments and care delivery models. To describe comparative and cost-effectiveness research; identify needed competencies for this research; identify federal funding; and describe current training opportunities. Published recommended competencies were reviewed. Current federal funding and training opportunities were identified. A federally funded training program and other training opportunities are described. Fourteen core competencies were identified that have both analytic and theoretical foci from nursing and other fields. There are multiple sources of federal funding for research and training. Interdisciplinary training is needed. Comparative and cost-effectiveness research has the opportunity to transform health care delivery and improve the outcomes of patients. Nurses, as clinicians and scientists, are in a unique position to contribute to this important research. We encourage nurses to seek the needed interdisciplinary research training to participate in this important endeavor. We also encourage educators to use the competencies and processes identified in current training programs to help shape their doctoral programs. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Faculty Professional Development Focused on Identifying Funding Opportunities: An Interactive Tool

    ERIC Educational Resources Information Center

    Moore, Alison L.; Reiser, Robert A.; Bradley, Terra W.; Zhao, Weinan

    2016-01-01

    In an effort to help faculty members learn about and obtain external funding for their research, a team of scholar-practitioners within a College of Education at a large southeastern university developed a database tool that enables faculty to identify grant opportunities aligned with their research interests and provides faculty with easy access…

  8. Anesthesiology leadership rounding: identifying opportunities for improvement.

    PubMed

    Gravenstein, Dietrich; Ford, Susan; Enneking, F Kayser

    2012-01-01

    Rounding that includes participation of individuals with authority to implement changes has been advocated as important to the transformation of an institution into a high-quality and safe organization. We describe a Department of Anesthesiology's experience with leadership rounding. The Department Chair or other senior faculty designate, a quality coordinator, up to four residents, the ward charge nurse, and patient nurses participated in rounds at bedsides. During a 23-month period, 14 significant opportunities to improve care were identified. Nurses identified 5 of these opportunities, primary team physicians 2, the rounding team 4, and patients or their family members another 3. The anesthesiology service had sole or shared responsibility for 10 improvements. A variety of organizations track specific measures across all phases of the patient experience to gauge quality of care. Chart auditing tools for detecting threats to safety are often used. These measures and tools missed opportunities for improvement that were discovered only through rounding. We conclude that the introduction of leadership rounding by an anesthesiology service can identify opportunities for improving quality that are not captured by conventional efforts.

  9. Identifying and Researching Market Opportunities for New High Technology Products.

    ERIC Educational Resources Information Center

    Dunstan, Peter

    Using a product called the synchro-pulse welder as a case study example, this paper discusses the activities of CSIRO (Commonwealth Scientific and Industrial Research Organisation) in identifying and marketing new high-technology products. A general discussion of CSIRO's market research plans includes two goals to be attained within the next 5…

  10. Integrating human health and environmental health into the DPSIR framework: a tool to identify research opportunities for sustainable and healthy communities.

    PubMed

    Yee, Susan H; Bradley, Patricia; Fisher, William S; Perreault, Sally D; Quackenboss, James; Johnson, Eric D; Bousquin, Justin; Murphy, Patricia A

    2012-12-01

    The U.S. Environmental Protection Agency has recently realigned its research enterprise around the concept of sustainability. Scientists from across multiple disciplines have a role to play in contributing the information, methods, and tools needed to more fully understand the long-term impacts of decisions on the social and economic sustainability of communities. Success will depend on a shift in thinking to integrate, organize, and prioritize research within a systems context. We used the Driving forces-Pressures-State-Impact-Response (DPSIR) framework as a basis for integrating social, cultural, and economic aspects of environmental and human health into a single framework. To make the framework broadly applicable to sustainability research planning, we provide a hierarchical system of DPSIR keywords and guidelines for use as a communication tool. The applicability of the integrated framework was first tested on a public health issue (asthma disparities) for purposes of discussion. We then applied the framework at a science planning meeting to identify opportunities for sustainable and healthy communities research. We conclude that an integrated systems framework has many potential roles in science planning, including identifying key issues, visualizing interactions within the system, identifying research gaps, organizing information, developing computational models, and identifying indicators.

  11. Qualitative research in rehabilitation science: opportunities, challenges, and future directions.

    PubMed

    VanderKaay, Sandra; Moll, Sandra E; Gewurtz, Rebecca E; Jindal, Pranay; Loyola-Sanchez, Adalberto; Packham, Tara L; Lim, Chun Y

    2018-03-01

    Qualitative research has had a significant impact within rehabilitation science over time. During the past 20 years the number of qualitative studies published per year in Disability and Rehabilitation has markedly increased (from 1 to 54). In addition, during this period there have been significant changes in how qualitative research is conceptualized, conducted, and utilized to advance the field of rehabilitation. The purpose of this article is to reflect upon the progress of qualitative research within rehabilitation to date, to explicate current opportunities and challenges, and to suggest future directions to continue to strengthen the contribution of qualitative research in this field. Relevant literature searches were conducted in electronic data bases and reference lists. Pertinent literature was examined to identify current opportunities and challenges for qualitative research use in rehabilitation and to identify future directions. Six key areas of opportunity and challenge were identified: (a) paradigm shifts, (b) advancements in methodology, (c) emerging technology, (d) advances in quality evaluation, (e) increasing popularity of mixed methods approaches, and (f) evolving approaches to knowledge translation. Two important future directions for rehabilitation are posited: (1) advanced training in qualitative methods and (2) engaging qualitative communities of research. Qualitative research is well established in rehabilitation and has an important place in the continued growth of this field. Ongoing development of qualitative researchers and methods are essential. Implications for Rehabilitation Qualitative research has the potential to improve rehabilitation practice by addressing some of the most pervasive concerns in the field such as practitioner-client interaction, the subjective and lived experience of disability, and clinical reasoning and decision making. This will serve to better inform those providing rehabilitation services thereby benefiting

  12. Identifying PHM market and network opportunities.

    PubMed

    Grube, Mark E; Krishnaswamy, Anand; Poziemski, John; York, Robert W

    2015-11-01

    Two key processes for healthcare organizations seeking to assume a financially sustainable role in population health management (PHM), after laying the groundwork for the effort, are to identify potential PHM market opportunities and determine the scope of the PHM network. Key variables organizations should consider with respect to market opportunities include the patient population, the overall insurance/employer market, and available types of insurance products. Regarding the network's scope, organizations should consider both traditional strategic criteria for a viable network and at least five additional criteria: network essentiality and PHM care continuum, network adequacy, service distribution right-sizing, network growth strategy, and organizational agility.

  13. Transformative research issues and opportunities in energy efficiency

    USDA-ARS?s Scientific Manuscript database

    This article presents a summary of research opportunities in energy efficiency identified in a workshop by a panel of experts assembled for the Civil, Mechanical and Manufacturing Innovation Division of the U.S. National Science Foundation. The workshop and article are restricted to two areas – red...

  14. Identifying regional opportunities for accelerated timber managemnet

    Treesearch

    David A. Gansner; Joseph E. Barnard; Samuel F. Gingrich; Samuel F. Gingrich

    1973-01-01

    Describes a procedure for identifying regional opportunities for accelerated timber management and demonstrates its application. Results provide a basis for rational choices among alternative management strategies and permit meaningful micro- and macro-evaluations of treatment response.

  15. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT - USDA BELTSVILLE AGRICULTURAL RESEARCH CENTER

    EPA Science Inventory

    A pollution prevention opportunity assessment (PPOA) was performed during the spring of 1991 which identified areas for waste reduction at the U.S. Department of Agriculture's Beltsville Agricultural Research Center (BARC), Beltsville, Maryland. he areas selected for this joint E...

  16. Identifying Opportunities in the Development of Ceramic Matrix Composite (CMC) Materials for Armor Applications

    DTIC Science & Technology

    2017-03-01

    a state of compression (Gooch 2002). At the same time research continues within the ceramics community to develop stronger and tougher ceramics...ARL-TR-7987 ● MAR 2017 US Army Research Laboratory Identifying Opportunities in the Development of Ceramic Matrix Composite (CMC...unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or

  17. Workshop on Basic Research Opportunities in Photovoltaics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Benner, J.; McConnell, R.; Deb, S., Editors

    1999-08-25

    The Basic Research Opportunities in Photovoltaics Workshop was held on May 3, 1999, in Seattle, Washington, in conjunction with the 195th Meeting of the Electrochemical Society. The workshop was structured into eight topics. Each topic area opened with a presentation in which the participants were asked to address the following: a brief introduction of the area of research; key research issues that were identified in an earlier workshop in 1992; what fundamental research has been done since then or is currently being done to address those issues; what are the research issues that are still relevant in light of advancesmore » made since the first workshop; identification of new fundamental research opportunities that will lead to important advances and innovations; and identification of significant commonalities and common research issues that have a cross-cutting impact, such as logically exist in silicon-based thin films, II-VI, and related materials. The topic areas discussed included amorphous and microcrystalline silicon, crystalline silicon, cadmium telluride, copper indium diselenide; III-V materials; novel materials and energy conversion approaches, semiconducting oxides, and characterization. After the meeting, participants in each working topic continued discussions by electronic means, completing journal articles that are to be published as a separate section in the ECS Proceedings of the ''PV for the 21st Century'' Symposium.« less

  18. Melanoma survivorship: research opportunities.

    PubMed

    Oliveria, Susan A; Hay, Jennifer L; Geller, Alan C; Heneghan, Maureen K; McCabe, Mary S; Halpern, Allan C

    2007-03-01

    The rising incidence and mortality rates of melanoma, the most fatal form of skin cancer, are among the greatest increases of all preventable cancers over the past decade. However, because of recent advances in early detection, secondary prevention efforts, and treatment, the number of melanoma survivors is increasing. Little research has been conducted on melanoma survivors and important opportunities exist for research in this understudied population. Here, we outline the important research opportunities related to the study of melanoma survivorship and summarize the paucity of literature currently available. A computerized literature search was performed of the MEDLINE database of the National Library of Medicine from 1966-2005. The scope of the search was limited to those studies published in English. The search was conducted using the following MeSH headings: melanoma, neoplasms, skin neoplasms, survival, and survival rate. The reference lists of relevant book chapters and review articles were further reviewed, and printed materials from recent scientific meetings addressing this topic were obtained. Several factors that affect melanoma survivors warrant further study, including: physiologic long-term effects; psychosocial, behavioral, and cognitive factors; demographic characteristics; surveillance practices; recurrences, secondary primaries, and other cancers; family members of survivors; and economic issues, access to health care/life insurance. Understanding recurrence and second primary cancer risk, psychosocial and cognitive characteristics, behaviors, surveillance patterns, economic sequelae, and family issues of melanoma survivors is important from a public health standpoint to promote the health and well-being of this cohort. Melanoma is an understudied cancer, and the incidence and mortality of this disease are increasing. Describing the long term burden of this cancer and identifying factors that contribute to them will facilitate efforts to develop

  19. Emerging Science and Research Opportunities for Metals and Metallic Nanostructures

    NASA Astrophysics Data System (ADS)

    Handwerker, Carol A.; Pollock, Tresa M.

    2014-07-01

    During the next decade, fundamental research on metals and metallic nanostructures (MMNs) has the potential to continue transforming metals science into innovative materials, devices, and systems. A workshop to identify emerging and potentially transformative research areas in MMNs was held June 13 and 14, 2012, at the University of California Santa Barbara. There were 47 attendees at the workshop (listed in the Acknowledgements section), representing a broad range of academic institutions, industry, and government laboratories. The metals and metallic nanostructures (MMNs) workshop aimed to identify significant research trends, scientific fundamentals, and recent breakthroughs that can enable new or enhanced MMN performance, either alone or in a more complex materials system, for a wide range of applications. Additionally, the role that MMN research can play in high-priority research and development (R&D) areas such as the U.S. Materials Genome Initiative, the National Nanotechnology Initiative, the Advanced Manufacturing Initiative, and other similar initiatives that exist internationally was assessed. The workshop also addressed critical issues related to materials research instrumentation and the cyberinfrastructure for materials science research and education, as well as science, technology, engineering, and mathematics (STEM) workforce development, with emphasis on the United States but with an appreciation that similar challenges and opportunities for the materials community exist internationally. A central theme of the workshop was that research in MMNs has provided and will continue to provide societal benefits through the integration of experiment, theory, and simulation to link atomistic, nanoscale, microscale, and mesoscale phenomena across time scales for an ever-widening range of applications. Within this overarching theme, the workshop participants identified emerging research opportunities that are categorized and described in more detail in the

  20. Challenges and opportunities for ELSI early career researchers.

    PubMed

    Bell, Jessica; Ancillotti, Mirko; Coathup, Victoria; Coy, Sarah; Rigter, Tessel; Tatum, Travis; Grewal, Jasjote; Akcesme, Faruk Berat; Brkić, Jovana; Causevic-Ramosevac, Anida; Milovanovic, Goran; Nobile, Marianna; Pavlidis, Cristiana; Finlay, Teresa; Kaye, Jane

    2016-07-08

    Over the past 25 years, there has been growing recognition of the importance of studying the Ethical, Legal and Social Implications (ELSI) of genetic and genomic research. A large investment into ELSI research from the National Institutes of Health (NIH) Human Genomic Project budget in 1990 stimulated the growth of this emerging field; ELSI research has continued to develop and is starting to emerge as a field in its own right. The evolving subject matter of ELSI research continues to raise new research questions as well as prompt re-evaluation of earlier work and a growing number of scholars working in this area now identify themselves as ELSI scholars rather than with a particular discipline. Due to the international and interdisciplinary nature of ELSI research, scholars can often find themselves isolated from disciplinary or regionally situated support structures. We conducted a workshop with Early Career Researchers (ECRs) in Oxford, UK, and this paper discusses some of the particular challenges that were highlighted. While ELSI ECRs may face many of the universal challenges faced by ECRs, we argue that a number of challenges are either unique or exacerbated in the case of ELSI ECRs and discuss some of the reasons as to why this may be the case. We identify some of the most pressing issues for ELSI ECRs as: interdisciplinary angst and expertise, isolation from traditional support structures, limited resources and funding opportunities, and uncertainty regarding how research contributions will be measured. We discuss the potential opportunity to use web 2.0 technologies to transform academic support structures and address some of the challenges faced by ELSI ECRs, by helping to facilitate mentoring and support, access to resources and new accreditation metrics. As our field develops it is crucial for the ELSI community to continue looking forward to identify how emerging digital solutions can be used to facilitate the international and interdisciplinary

  1. New opportunities for social research on forest landowners in the south

    Treesearch

    John Schelhas; Robert Zabawa; Joseph J. Molnar

    2003-01-01

    Many of the issues of importance to forest management and policy have important social components. Yet, in the South, social research on forests has lagged behind economic and biophysical research. In this paper we identify some important new opportunities for social research on forests in the South, focusing on non industrial private forests because they represent the...

  2. Space robotics: Recent accomplishments and opportunities for future research

    NASA Technical Reports Server (NTRS)

    Montgomery, Raymond C.; Buttrill, Carey S.; Dorsey, John T.; Juang, Jer-Nan; Lallman, Frederick J.; Moerder, Daniel D.; Scott, Michael A.; Troutman, Patrick; Williams, Robert L., II

    1992-01-01

    The Langley Guidance, Navigation, and Control Technical Committee (GNCTC) was one of six technical committees created in 1991 by the Chief Scientist, Dr. Michael F. Card. During the kickoff meeting Dr. Card charged the chairmen to: (1) establish a cross-Center committee; (2) support at least one workshop in a selected discipline; and (3) prepare a technical paper on recent accomplishments in the discipline and on opportunities for future research. The Guidance, Navigation, and Control Committee was formed and selected for focus on the discipline of Space robotics. This report is a summary of the committee's assessment of recent accomplishments and opportunities for future research. The report is organized as follows. First is an overview of the data sources used by the committee. Next is a description of technical needs identified by the committee followed by recent accomplishments. Opportunities for future research ends the main body of the report. It includes the primary recommendation of the committee that NASA establish a national space facility for the development of space automation and robotics, one element of which is a telerobotic research platform in space. References 1 and 2 are the proceedings of two workshops sponsored by the committee during its June 1991, through May 1992 term. The focus of the committee for the June 1992 - May 1993 term will be to further define to the recommended platform in space and to add an additional discipline which includes aircraft related GN&C issues. To the latter end members performing aircraft related research will be added to the committee. (A preliminary assessment of future opportunities in aircraft-related GN&C research has been included as appendix A.)

  3. Luquillo Experimental Forest: Research History and Opportunities

    Treesearch

    Nancy L. Harris; Ariel E. Lugo; Sandra Brown; Tamara Heartsill-Scalley

    2012-01-01

    The goals of this Luquillo Experimental Forest: Research History and Opportunities are to synthesize the new research that has emerged from the LEF since the publication of Brown et al. (1983) into a concise summary of key research findings and to highlight opportunities for future research that will contribute to a greater understanding of the structure and function...

  4. Disaster Research: A Nursing Opportunity

    PubMed Central

    Savage, Jane; Barcelona-deMendoza, Veronica; Harville, Emily W.

    2013-01-01

    Nurses working or living near a community disaster have the opportunity to study health-related consequences to disaster or disaster recovery. In such a situation, the researchers need to deal with the conceptual and methodological issues unique to post-disaster research and know what resources are available to guide them, even if they have no specialized training or previous experience in disaster research. The purpose of this article is to review issues and challenges associated with conducting post-disaster research and encourage nurses to seek resources and seize opportunities to conduct research should the situation arise. Current disaster studies and the authors’ personal experiences conducting maternal-child research in post-Katrina New Orleans (2005–2013) provide real-life examples of how health professionals and nurses faced the challenges of doing post-disaster research. After catastrophic events, nurses need to step forward to conduct disaster research that informs and improves future disaster planning and health care responses. PMID:23899191

  5. HIV prevention among diverse young MSM: Research needs, priorities, and opportunities

    PubMed Central

    Rhodes, Scott D.; Wong, Frank Y.

    2016-01-01

    There remains a profound need for innovative and effective interventions designed for young men who have sex with men (YMSM) generally; and racial and ethnic minority YMSM, YMSM living in rural communities, and low-income YMSM, particularly, to prevent HIV and improve health outcomes in the United States. This introduction to this theme issue identifies some of the research needs, priorities, and opportunities that emerged during a seminal NIMHD-sponsored workshop on HIV prevention behavioral interventions for diverse YMSM. It provides researchers, practitioners, and federal partners guidance in next steps to reduce the impact of the HIV epidemic among YMSMS. The needs, priorities, and opportunities identified serve as a foundation to push both the science and the practice of HIV prevention forward. We recognize that considerably more research is needed, and this issue highlights intervention research – where we have been and where we should go. With the disparities faced by YMSM, we must act rapidly to do the work it will take to meet their prevention needs, reduce infections, and save lives. PMID:27244188

  6. Opportunities for research in aerothermodynamics

    NASA Technical Reports Server (NTRS)

    Graham, R. W.

    1983-01-01

    "Aerothermodynamics' involves the disciplines of chemistry, thermodynamics, fluid mechanics and heat transfer which have collaborative importance in propulsion systems. There are growing opportunities for the further application of these disciplines to improve the methodology for the design of advanced gas turbines; particularly, the combustor and turbine. Design procedures follow empirical or cut and try guidelines. The tremendous advances in computational analysis and in instrumentation techniques hold promise for research answers to complex physical processes that are currently not well understood. The transfer of basic research understanding to engineering design should result in shorter, less expensive development commitments for engines. The status and anticipated opportunities in research topics relevant to combustors and turbines is reviewed.

  7. Internships, employment opportunities, and research grants

    USGS Publications Warehouse

    ,

    2015-01-01

    As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that threaten us. Opportunities for undergraduate and graduate students and faculty to participate in USGS science are available in the selected programs described below. Please note: U.S. citizenship is required for all government positions.This publication has been superseded by USGS General Information Product 165 Grant Opportunities for Academic Research and Training and USGS General Information Product 166 Student and Recent Graduate Employment Opportunities.This publication is proceeded by USGS General Information Product 80 Internships, Employment Opportunities, and Research Grants published in 2008.

  8. Nurse Satisfaction With Opportunities to Engage in Research.

    PubMed

    Hagan, Joseph

    2018-02-01

    Nurses should be able to participate in research and integrate evidence from research into practice; however, studies investigating factors related to nurse satisfaction with opportunities to engage in research are lacking. A questionnaire was distributed to nurses employed at two sites: a hospital and a nursing school. Only 16% of nurses reported being satisfied with opportunities to engage in research. In multivariate analysis, degree of belief that resources are a barrier to research was inversely proportional to satisfaction with nursing research opportunities (adjusted odds ratio = 0.13, p < .001), whereas perception that personal relevance is a barrier to research was associated with increased satisfaction (adjusted odds ratio = 2.38, p < .001). Satisfaction with opportunities to engage in research is low. Incentivizing nursing research and providing protected research time, training and education, and mentors to guide nurses through the research process could be effective strategies for increasing satisfaction and research productivity, thereby strengthening evidence-based practice.

  9. Hydrological connectivity for riverine fish: measurement challenges and research opportunities

    Treesearch

    A.H. Fullerton; Kelly Burnett; Ashley Steel; Rebecca Flitcroft; G.R. Pess; B.E. Feist; C.E. Torgersen; D.J. Miller; B.L. Sanderson

    2010-01-01

    In this review, we first summarize how hydrologic connectivity has been studied for riverine fish capable of moving long distances, and then identify research opportunities that have clear conservation significance. Migratory species, such as anadromous salmonids, are good model organisms for understanding ecological connectivity in rivers because the spatial scale...

  10. Fostering Students' Competence in Identifying Business Opportunities in Entrepreneurship Education

    ERIC Educational Resources Information Center

    Karimi, Saeid; Biemans, Harm J. A.; Lans, Thomas; Aazami, Mousa; Mulder, Martin

    2016-01-01

    Opportunity identification and, in particular, the generation of new business ideas is becoming an important element of entrepreneurship education. Researchers and educators, however, struggle with how opportunity identification competence can be enhanced. The purpose of this study was, therefore, to test the ability of students to generate new…

  11. HIV Prevention Among Diverse Young MSM: Research Needs, Priorities, and Opportunities.

    PubMed

    Rhodes, Scott D; Wong, Frank Y

    2016-06-01

    There remains a profound need for innovative and effective interventions designed for young men who have sex with men (YMSM) generally, and racial and ethnic minority YMSM, YMSM living in rural communities, and low-income YMSM, particularly, to prevent HIV and improve health outcomes in the United States. This introduction to this theme issue, "Behavioral HIV Prevention Interventions for Diverse YMSM," of AIDS Education and Prevention identifies some of the research needs, priorities, and opportunities that emerged during a seminal NIMHD-sponsored workshop on HIV prevention behavioral interventions for diverse YMSM. It provides researchers, practitioners, and federal partners guidance in next steps to reduce the impact of the HIV epidemic among YMSM. The needs, priorities, and opportunities identified serve as a foundation to push both the science and the practice of HIV prevention forward. We recognize that considerably more research is needed, and this issue highlights intervention research-where we have been and where we should go. With the disparities faced by YMSM, we must act rapidly to do the work it will take to meet their prevention needs, reduce infections, and save lives.

  12. Clinical Research Informatics: Challenges, Opportunities and Definition for an Emerging Domain

    PubMed Central

    Embi, Peter J.; Payne, Philip R.O.

    2009-01-01

    Objectives Clinical Research Informatics, an emerging sub-domain of Biomedical Informatics, is currently not well defined. A formal description of CRI including major challenges and opportunities is needed to direct progress in the field. Design Given the early stage of CRI knowledge and activity, we engaged in a series of qualitative studies with key stakeholders and opinion leaders to determine the range of challenges and opportunities facing CRI. These phases employed complimentary methods to triangulate upon our findings. Measurements Study phases included: 1) a group interview with key stakeholders, 2) an email follow-up survey with a larger group of self-identified CRI professionals, and 3) validation of our results via electronic peer-debriefing and member-checking with a group of CRI-related opinion leaders. Data were collected, transcribed, and organized for formal, independent content analyses by experienced qualitative investigators, followed by an iterative process to identify emergent categorizations and thematic descriptions of the data. Results We identified a range of challenges and opportunities facing the CRI domain. These included 13 distinct themes spanning academic, practical, and organizational aspects of CRI. These findings also informed the development of a formal definition of CRI and supported further representations that illustrate areas of emphasis critical to advancing the domain. Conclusions CRI has emerged as a distinct discipline that faces multiple challenges and opportunities. The findings presented summarize those challenges and opportunities and provide a framework that should help inform next steps to advance this important new discipline. PMID:19261934

  13. Compelling Research Opportunities using Isotopes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Isotopes are vital to the science and technology base of the US economy. Isotopes, both stable and radioactive, are essential tools in the growing science, technology, engineering, and health enterprises of the 21st century. The scientific discoveries and associated advances made as a result of the availability of isotopes today span widely from medicine to biology, physics, chemistry, and a broad range of applications in environmental and material sciences. Isotope issues have become crucial aspects of homeland security. Isotopes are utilized in new resource development, in energy from bio-fuels, petrochemical and nuclear fuels, in drug discovery, health care therapies andmore » diagnostics, in nutrition, in agriculture, and in many other areas. The development and production of isotope products unavailable or difficult to get commercially have been most recently the responsibility of the Department of Energy's Nuclear Energy program. The President's FY09 Budget request proposed the transfer of the Isotope Production program to the Department of Energy's Office of Science in Nuclear Physics and to rename it the National Isotope Production and Application program (NIPA). The transfer has now taken place with the signing of the 2009 appropriations bill. In preparation for this, the Nuclear Science Advisory Committee (NSAC) was requested to establish a standing subcommittee, the NSAC Isotope Subcommittee (NSACI), to advise the DOE Office of Nuclear Physics. The request came in the form of two charges: one, on setting research priorities in the short term for the most compelling opportunities from the vast array of disciplines that develop and use isotopes and two, on making a long term strategic plan for the NIPA program. This is the final report to address charge 1. NSACI membership is comprised of experts from the diverse research communities, industry, production, and homeland security. NSACI discussed research opportunities divided into three areas: (1

  14. Nanoparticle puzzles and research opportunities that go beyond state of the art.

    PubMed

    Jee, Ah-Young; Lou, Kai; Jang, Hyun-Sook; Nagamanasa, K Hima; Granick, Steve

    2016-01-01

    We present an overview of current progress and research challenges in the field of nanoparticle assembly, touching on the following topics: (1) historical perspective; (2) consideration of what is a nanoparticle; (3) contrast between nanoparticle self-assembly and top-down construction; (4) opportunities for nanoparticles with more intelligent sub-structures; (5) opportunities for nanoparticle systems cued to interact subtly in space and time. In this personal and subjective account, certain holy grails for nanoparticle science and technology are identified.

  15. Identification of energy conservation research opportunities: a review and synthesis of the literature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hopp, W.J.; Hane, G.J.; Gurwell, W.E.

    1982-03-01

    Thirty-eight studies of energy conservation research opportunities are reviewed. The 38 studies chosen for review include many of the major efforts in the identification of energy conservation research and development (R and D) opportunities and provide a representative sample of the types of studies that have been performed. The sample includes studies that focus on specific energy use (e.g., auto transport), as well as studies that focus on specific types of research (e.g., materials science). The sample also includes studies that can be further contrasted in terms of long-term vs. short-term projects, evolutionary vs. revolutionary ideas, generic vs. process-specific activities,more » and technology base research vs. hardware development. Each of these perspectives contributes toward assuring coverage of the breadth of energy conservation R and D opportunities. In each review the technical or end-use focus is described, the research ideas identified in the study are listed, and a critical summary is given. The reviews also indicate whether the studies present end-use consumption data, estimate potential energy savings, estimate times to commercialization, summarize existing research programs, or describe the identification methodology. In Section 2.0 the various research studies are compared. In Section 3.0 the characteristics of an aggregate list of research ideas are discussed. The characteristics were collected from the research opportunities studies, which are included in Appendix A. Appendix A contains a compilation of energy conservation R and D opportunities arranged by energy end-use applications. Appendix B contains an outline of the format followed in writing the critical reviews of the studies, the individual study reviews, and the extended bibliography of 88 studies that describe energy conservation research opportunities.« less

  16. Identifying Priorities for Post-Secondary Education in Qatar. Research Brief

    ERIC Educational Resources Information Center

    Stasz, Cathleen; Eide, Eric R.; Martorell, Francisco; Salem, Hanine; Constant, Louay; Goldman, Charles A.; Moini, Joy S.; Nadareishvili, Vazha

    2007-01-01

    Although Qatar has improved its post-secondary educational opportunities, the country's efforts have not undergone a broad strategic review. This study analyzed the extent to which the current offerings can meet the country's future needs and identified priorities for developing further educational options. Researchers found that Qataris' current…

  17. Undergraduate Research Mentoring: Obstacles and Opportunities

    ERIC Educational Resources Information Center

    Johnson, W. Brad; Behling, Laura L.; Miller, Paul; Vandermaas-Peeler, Maureen

    2015-01-01

    Researchers and policy-makers in higher education increasingly espouse the view that undergraduate students should have the opportunity to learn about scholarship and research in the context of faculty-mentored research experiences. There is mounting consensus that mentored undergraduate research should be standard pedagogical practice in all…

  18. Identifying Opportunities in Citizen Science for Academic Libraries

    ERIC Educational Resources Information Center

    Cohen, Cynthia M.; Cheney, Liz; Duong, Khue; Lea, Ben; Unno, Zoe Pettway

    2015-01-01

    Citizen science projects continue to grow in popularity, providing opportunities for nonexpert volunteers to contribute to and become personally invested in rigorous scientific research. Academic libraries, aiming to promote and provide tools and resources to master scientific and information literacy, can support these efforts. While few examples…

  19. EUFAR training opportunities to advance European airborne research

    NASA Astrophysics Data System (ADS)

    Reusen, I.; Brenguier, J.-L.; Brown, P.; Wendish, M.

    2009-04-01

    EUFAR, EUropean Facilities for Airborne Research, is an FP7 project (http://www.eufar.net) funded by the European Commission with 33 partners that aims at providing and improving the access to European airborne facilities (i.e. aircraft, airborne instruments, data processing centres) for researchers in environmental and geo-sciences through Networking Activities, Transnational Access and Joint Research Activities. This paper reports on the training opportunities within EUFAR for European researchers. In EUFAR three types of training opportunities are offered: 1) Participate in training courses (ET-TC) 2) Join an existing field campaign (ET-EC) 3) Participate in the design of a new field campaign (ET-TA), in the frame of EUFAR Transnational Access and tutored by more experienced researchers. During the 4-year EUFAR project (2008-2012), 4 training courses covering the complete chain from acquisition to interpretation of airborne data and images will be organised during spring/summer for early-stage researchers as well as university lecturers (new in FP7 EUFAR) in airborne research. The training courses will have an equal focus on theory and practical training/demonstration and each training course will be accompanied by a "student" airborne field campaign. Participants will be trained by top-class scientists, aircraft and/or instrument operators and each participant will get the opportunity to design his/her own experiment and to participate to that flight experiment. Furthermore, researchers have the opportunity to join an existing field campaign and work with more experienced researchers, aircraft and/or instrument operators. The list of airborne field campaigns open to join and the eligibility criteria, can be consulted at the EUFAR website. Finally, researchers have the opportunity to participate in the design of a new field campaign in the frame of EUFAR Transnational Access (TA). TA provides access to either aircraft or instrumentation that are not otherwise

  20. Indian Ocean research: Opportunities and challenges

    NASA Astrophysics Data System (ADS)

    Hood, Raleigh R.; Wiggert, Jerry D.; Naqvi, S. Wajih A.

    Historically, the Indian Ocean (IO) has received relatively little attention from the oceanographic community and therefore remains substantially undersampled compared to the Atlantic and Pacific oceans. This situation is compounded by the IO being a dynamically complex and highly variable system under monsoonal influence. The biogeochemical and ecological impacts of this complex physical forcing are not yet fully understood. Specific questions and hypotheses have emerged from recent studies that have yet to be tested, such as the potential role of zooplankton grazing versus iron limitation in controlling phytoplankton production in the Arabian Sea (AS). Furthermore, the IO is a globally important denitrification zone, and it also appears to be a region where N2 fixation rates are significant. However, there are still large uncertainties in the rate estimates for both. The IO is also warming rapidly, but the impacts of this warming on the biota, carbon uptake, and nitrogen cycling are unquantified. The increasing population density and rapid economic growth of the countries surrounding the Bay of Bengal and eastern AS make these regions' coastal environments particularly vulnerable to anthropogenic influences. Warming and anthropogenic effects might also impact the huge myctophid stocks in the AS and other commercially valuable species. These potential influences and their socioeconomic ramifications need to be explored. Deployment of coastal and open ocean observing systems in the IO has created new opportunities for carrying out biogeochemical and ecological research. International research efforts should be motivated to exploit these opportunities for addressing the questions identified in this chapter.

  1. Big biomedical data and cardiovascular disease research: opportunities and challenges.

    PubMed

    Denaxas, Spiros C; Morley, Katherine I

    2015-07-01

    Electronic health records (EHRs), data generated and collected during normal clinical care, are increasingly being linked and used for translational cardiovascular disease research. Electronic health record data can be structured (e.g. coded diagnoses) or unstructured (e.g. clinical notes) and increasingly encapsulate medical imaging, genomic and patient-generated information. Large-scale EHR linkages enable researchers to conduct high-resolution observational and interventional clinical research at an unprecedented scale. A significant amount of preparatory work and research, however, is required to identify, obtain, and transform raw EHR data into research-ready variables that can be statistically analysed. This study critically reviews the opportunities and challenges that EHR data present in the field of cardiovascular disease clinical research and provides a series of recommendations for advancing and facilitating EHR research.

  2. Transforming Undergraduate Research Opportunities Using Telepresence

    ERIC Educational Resources Information Center

    Pallant, Amy; McIntyre, Cynthia; Stephens, A. Lynn

    2016-01-01

    The National Science Foundation funded the "Transforming Remotely Conducted Research through Ethnography, Education, and Rapidly Evolving Technologies" (TREET) project to explore ways to utilize advances in technology and thus to provide opportunities for scientists and undergraduate students to engage in deep sea research. The…

  3. Field potential soil variability index to identify precision agriculture opportunity

    USDA-ARS?s Scientific Manuscript database

    Precision agriculture (PA) technologies used for identifying and managing within-field variability are not widely used despite decades of advancement. Technological innovations in agronomic tools, such as canopy reflectance or electrical conductivity sensors, have created opportunities to achieve a ...

  4. Research opportunities to advance solar energy utilization.

    PubMed

    Lewis, Nathan S

    2016-01-22

    Major developments, as well as remaining challenges and the associated research opportunities, are evaluated for three technologically distinct approaches to solar energy utilization: solar electricity, solar thermal, and solar fuels technologies. Much progress has been made, but research opportunities are still present for all approaches. Both evolutionary and revolutionary technology development, involving foundational research, applied research, learning by doing, demonstration projects, and deployment at scale will be needed to continue this technology-innovation ecosystem. Most of the approaches still offer the potential to provide much higher efficiencies, much lower costs, improved scalability, and new functionality, relative to the embodiments of solar energy-conversion systems that have been developed to date. Copyright © 2016, American Association for the Advancement of Science.

  5. Future Research Opportunities in Peri-Prosthetic Joint Infection Prevention.

    PubMed

    Berbari, Elie; Segreti, John; Parvizi, Javad; Berríos-Torres, Sandra I

    Peri-prosthetic joint infection (PJI) is a serious complication of prosthetic joint arthroplasty. A better understanding and reversal of modifiable risk factors may lead to a reduction in the incidence of incisional (superficial and deep) and organ/space (e.g., PJI) surgical site infections (SSI). Recently, the Centers for Disease Control and Prevention (CDC) and the Healthcare Infection Control Practices Advisory Committee (HICPAC) published the Guideline for Prevention of Surgical Site Infection. This targeted update applies evidence-based methodology in drafting recommendations for potential strategies to reduce the risk of SSI both across surgical procedures and specifically in prosthetic joint arthroplasty. A panel of PJI content experts identified nine PJI prevention research opportunities based on both evidence gaps identified through the guideline development process (transfusion, immunosuppressive therapy, anticoagulation, orthopedic space suit, and biofilm) and expert opinion (anesthesia, operative room environment, glycemic control, and Staphylococcus aureus nasal screening and decolonization. This article offers a road map for PJI prevention research.

  6. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies.

    PubMed

    D'Onofrio, Gail; Jauch, Edward; Jagoda, Andrew; Allen, Michael H; Anglin, Deirdre; Barsan, William G; Berger, Rachel P; Bobrow, Bentley J; Boudreaux, Edwin D; Bushnell, Cheryl; Chan, Yu-Feng; Currier, Glenn; Eggly, Susan; Ichord, Rebecca; Larkin, Gregory L; Laskowitz, Daniel; Neumar, Robert W; Newman-Toker, David E; Quinn, James; Shear, Katherine; Todd, Knox H; Zatzick, Douglas

    2010-11-01

    The Institute of Medicine Committee on the Future of Emergency Care in the United States Health System (2003) identified a need to enhance the research base for emergency care. As a result, a National Institutes of Health (NIH) Task Force on Research in Emergency Medicine was formed to enhance NIH support for emergency care research. Members of the NIH Task Force and academic leaders in emergency care participated in 3 Roundtable discussions to prioritize current opportunities for enhancing and conducting emergency care research. We identify key research questions essential to advancing the science of emergency care and discuss the barriers and strategies to advance research by exploring the collaboration between NIH and the emergency care community. Experts from emergency medicine, neurology, psychiatry, and public health assembled to review critical areas in need of investigation, current gaps in knowledge, barriers, and opportunities. Neurologic emergencies included cerebral resuscitation, pain, stroke, syncope, traumatic brain injury, and pregnancy. Mental health topics included suicide, agitation and delirium, substances, posttraumatic stress, violence, and bereavement. Presentations and group discussion firmly established the need for translational research to bring basic science concepts into the clinical arena. A coordinated continuum of the health care system that ensures rapid identification and stabilization and extends through discharge is necessary to maximize overall patient outcomes. There is a paucity of well-designed, focused research on diagnostic testing, clinical decisionmaking, and treatments in the emergency setting. Barriers include the limited number of experienced researchers in emergency medicine, limited dedicated research funding, and difficulties of conducting research in chaotic emergency environments stressed by crowding and limited resources. Several themes emerged during the course of the roundtable discussion, including the need

  7. Opportunities and Constraints in Disseminating Qualitative Research in Web 2.0 Virtual Environments.

    PubMed

    Hays, Charles A; Spiers, Judith A; Paterson, Barbara

    2015-11-01

    The Web 2.0 digital environment is revolutionizing how users communicate and relate to each other, and how information is shared, created, and recreated within user communities. The social media technologies in the Web 2.0 digital ecosystem are fundamentally changing the opportunities and dangers in disseminating qualitative health research. The social changes influenced by digital innovations shift dissemination from passive consumption to user-centered, apomediated cooperative approaches, the features of which are underutilized by many qualitative researchers. We identify opportunities new digital media presents for knowledge dissemination activities including access to wider audiences with few gatekeeper constraints, new perspectives, and symbiotic relationships between researchers and users. We also address some of the challenges in embracing these technologies including lack of control, potential for unethical co-optation of work, and cyberbullying. Finally, we offer solutions to enhance research dissemination in sustainable, ethical, and effective strategies. © The Author(s) 2015.

  8. The art of research: Opportunities for a science-based approach

    DOE PAGES

    Silva, Austin Ray; Avina, Glory Emmanuel; Tsao, Jeffrey Y.

    2016-02-01

    Research, the manufacture of knowledge, is currently practiced largely as an “art,” not a “science.” Just as science (understanding) and technology (tools) have revolutionized the manufacture of other goods and services, it is natural, perhaps inevitable, that they will ultimately also be applied to the manufacture of knowledge. In this article, we present an emerging perspective on opportunities for such application, at three different levels of the research enterprise. At the cognitive science level of the individual researcher, opportunities include: overcoming idea fixation and sloppy thinking, and balancing divergent and convergent thinking. At the social network level of the researchmore » team, opportunities include: overcoming strong links and groupthink, and optimally distributing divergent and convergent thinking between individuals and teams. At the research ecosystem level of the research institution and the larger national and international community of researchers, opportunities include: overcoming GPA and performance fixation, overcoming narrow measures of research impact, and overcoming (or harnessing) existential/social stress.« less

  9. The art of research: Opportunities for a science-based approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Silva, Austin Ray; Avina, Glory Emmanuel; Tsao, Jeffrey Y.

    Research, the manufacture of knowledge, is currently practiced largely as an “art,” not a “science.” Just as science (understanding) and technology (tools) have revolutionized the manufacture of other goods and services, it is natural, perhaps inevitable, that they will ultimately also be applied to the manufacture of knowledge. In this article, we present an emerging perspective on opportunities for such application, at three different levels of the research enterprise. At the cognitive science level of the individual researcher, opportunities include: overcoming idea fixation and sloppy thinking, and balancing divergent and convergent thinking. At the social network level of the researchmore » team, opportunities include: overcoming strong links and groupthink, and optimally distributing divergent and convergent thinking between individuals and teams. At the research ecosystem level of the research institution and the larger national and international community of researchers, opportunities include: overcoming GPA and performance fixation, overcoming narrow measures of research impact, and overcoming (or harnessing) existential/social stress.« less

  10. Research and Development Opportunities for Joining Technologies in HVAC&R

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goetzler, William; Guernsey, Matt; Young, Jim

    The Building Technologies Office (BTO) works with researchers and industry partners to develop and deploy technologies that can substantially reduce energy consumption and greenhouse gas (GHG) emissions in residential and commercial buildings. This opportunity assessment aims to advance BTO’s energy savings, GHG reduction, and other program goals by identifying research and development (R&D) initiatives for joining technologies in heating, ventilation, air-conditioning, and refrigeration (HVAC&R) systems. Improving joining technologies for HVAC&R equipment has the potential to increase lifetime equipment operating efficiency, decrease equipment and project cost, and most importantly reduce hydroflourocarbon (HFC) refrigerant leakage to support HFC phasedown and GHG reductionmore » goals.« less

  11. Identifying Links Between Sexual Violence and Youth Violence Perpetration: New Opportunities for Sexual Violence Prevention

    PubMed Central

    DeGue, Sarah; Massetti, Greta M.; Holt, Melissa K.; Tharp, Andra Teten; Valle, Linda Anne; Matjasko, Jennifer L.; Lippy, Caroline

    2018-01-01

    Objective One promising opportunity for advancing sexual violence (SV) research and identifying new avenues for prevention involves examining other forms of violence that may share risk factors with SV. Youth violence (YV) is ideal for consideration given evidence of overlap in SV and YV risk factors, a large set of established YV risk factors across the social ecology, and the number of evidence-based YV prevention strategies available. The current paper identifies shared and unique risk factors for SV and YV and highlights evidence-based YV prevention strategies that impact these shared risk factors. Conclusions Researchers and program developers should consider adapting and evaluating evidence-based YV prevention strategies to prevent SV. Modifying these programs to address SV’s unique risk factors may maximize their potential effectiveness. In addition, expanding SV research at the outer levels of the social ecology is critical to developing community-level prevention strategies. The YV literature suggests several potential risk factors at these levels in need of research for SV, including school connectedness, social disorganization, and availability of alcohol and drugs. Using the YV literature as a starting point for expanding SV research leverages prior investments in YV research, may help identify new SV prevention strategies at a limited cost, and moves the field more quickly toward implementation of cost-effective, multidomain violence prevention strategies in communities. PMID:29644117

  12. Latinos and HIV/AIDS: Examining Factors Related to Disparity and Identifying Opportunities for Psychosocial Intervention Research

    PubMed Central

    Hendriksen, Ellen Setsuko; Collins, Erin Marie; Durán, Ron E.; Safren, Steven A.

    2013-01-01

    Latinos maintain an AIDS case rate more than 3 times higher than whites, a greater rate of progression to AIDS, and a higher rate of HIV/AIDS-related deaths. Three broad areas are reviewed related to these disparities: (1) relevant demographic, socioeconomic, and socio-cultural factors among Latinos; (2) drug abuse and mental health problems in Latinos relevant to HIV/AIDS outcomes; and (3) opportunities for psychosocial intervention. Latinos living with HIV are a rapidly growing group, are more severely impacted by HIV than whites, and confront unique challenges in coping with HIV/AIDS. A body of research suggests that depression, substance abuse, treatment adherence, health literacy, and access to healthcare may be fruitful targets for intervention research in this population. Though limited, the current literature suggests that psychosocial interventions that target these factors could help reduce HIV/AIDS disparities between Latinos and whites and could have important public health value. PMID:18498050

  13. Identifying excessive vehicle idling and opportunities for off-road fuel tax credits for stationary operations in the Caltrans fleet, phase 1

    DOT National Transportation Integrated Search

    2011-01-01

    This report documents the research project Identifying Excessive Vehicle Idling and Opportunities for Off-Road Fuel Tax Credits for : Stationary Operations in the Caltrans Fleet - Phase 1, performed in response to a California Department of Tra...

  14. Suborbital Research and Development Opportunities

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.

    2011-01-01

    This slide presentation reviews the new strategies for problem solving in the life sciences in the suborbital realm. Topics covered are: an overview of the space life sciences, the strategic initiatives that the Space Life Sciences organization engaged in, and the new business model that these initiatives were developed. Several opportunities for research are also reviewed.

  15. Overview of Space Science and Information Research Opportunities at NASA

    NASA Technical Reports Server (NTRS)

    Green, James L.

    2000-01-01

    It is not possible to review all the opportunities that NASA provides to support the Space Science Enterprise, in the short amount of time allotted for this presentation. Therefore, only a few key programs will be discussed. The programs that I will discuss will concentrate on research opportunities for faculty, graduate and postdoctoral candidates in Space Science research and information technologies at NASA. One of the most important programs for research opportunities is the NASA Research Announcement or NRA. NASA Headquarters issues NRA's on a regular basis and these cover space science and computer science activities relating to NASA missions and programs. In the Space Sciences, the most important NRA is called the "Research Opportunities in Space Science or the ROSS NRA. The ROSS NRA is composed of multiple announcements in the areas of structure and evolution of the Universe, Solar System exploration, Sun-Earth connections, and applied information systems. Another important opportunity is the Graduate Student Research Program (GSRP). The GSRP is designed to cultivate research ties between a NASA Center and the academic community through the award of fellowships to promising students in science and engineering. This program is unique since it matches the student's area of research interest with existing work being carried out at NASA. This program is for U.S. citizens who are full-time graduate students. Students who are successful have made the match between their research and the NASA employee who will act as their NASA Advisor/ Mentor. In this program, the student's research is primarily accomplished under the supervision of his faculty advisor with periodic or frequent interactions with the NASA Mentor. These interactions typically involve travel to the sponsoring NASA Center on a regular basis. The one-year fellowships are renewable for up to three years and over $20,000 per year. These and other important opportunities will be discussed.

  16. Identifying Sustainable Design Opportunities in Tribal Hotels and Casinos: Mescalero Inn of the Mountain Gods Hotel and Casino

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fuller, Diana; Martino, Anthony; Begay, Sandra K.

    The Indian Gaming Regulatory Act, passed by Congress on October 17, 1988 provided tribes with the Federal statute to pursue gaming activities on tribal lands. Many Native communities contribute to larger regional economies and tourism industries. These casino facilities often include resort-style hotel amenities. Not surprisingly, they are also large consumers of energy, operating 24 hours a day and 7 days a week. Tribes with hotels and casinos can implement sustainable design features and not only receive economic gain, but also environmental and community benefits. The intention of this paper is to identify sustainable design opportunities at the Inn ofmore » the Mountain Gods Hotel and Casino. This research stems from previous work the researcher conducted and subsequently published for the Illinois Green Business Association. First, the paper reviews what sustainable design is and points of interest when considering sustainable construction. Next, the paper explores the precedents set by the Blue Lake Rancheria, Rincon Band of Luiseno Indians, and the Forest County Potawatomi Tribe. Then, the research examines areas to collect baseline information and identify opportunities in sustainable design for the Mescalero Apache Tribe, Inn of the Mountain Gods Hotel and Casino located in New Mexico. Lastly, the work explores the resources and funding options available to the tribe.« less

  17. [Strengths, weaknesses, and opportunities of French research in trophic ecology].

    PubMed

    Perga, Marie-Élodie; Danger, Michael; Dubois, Stanislas; Fritch, Clémentine; Gaucherel, Cédric; Hubas, Cedric; Jabot, Franck; Lacroix, Gérard; Lefebvre, Sébastien; Marmonier, Pierre; Bec, Alexandre

    2018-05-30

    The French National Institute of Ecology and Environment (INEE) aims at fostering pluridisciplinarity in Environmental Science and, for that purpose, funds ex muros research groups (GDR) on thematic topics. Trophic ecology has been identified as a scientific field in ecology that would greatly benefit from such networking activity, as being profoundly scattered. This has motivated the seeding of a GDR, entitled "GRET". The contours of the GRET's action, and its ability to fill these gaps within trophic ecology at the French national scale, will depend on the causes of this relative scattering. This study relied on a nationally broadcasted poll aiming at characterizing the field of trophic ecology in France. Amongst all the unique individuals that fulfilled the poll, over 300 belonged at least partly to the field of trophic ecology. The sample included all French public research institutes and career stages. Three main disruptions within the community of scientist in trophic ecology were identified. The first highlighted the lack of interfaces between microbial and trophic ecology. The second evidenced that research questions were strongly linked to single study fields or ecosystem type. Last, research activities are still quite restricted to the ecosystem boundaries. All three rupture points limit the conceptual and applied progression in the field of trophic ecology. Here we show that most of the disruptions within French Trophic Ecology are culturally inherited, rather than motivated by scientific reasons or justified by socio-economic stakes. Comparison with the current literature confirms that these disruptions are not necessarily typical of the French research landscape, but instead echo the general weaknesses of the international research in ecology. Thereby, communication and networking actions within and toward the community of trophic ecologists, as planned within the GRET's objectives, should contribute to fill these gaps, by reintegrating microbes within

  18. Emerging technologies and web accessibility: research challenges and opportunities focussing on vision issues.

    PubMed

    Harper, Simon; Yesilada, Yeliz

    2012-01-01

    This is a technological review paper focussed on identifying both the research challenges and opportunities for further investigation arising from emerging technologies, and it does not aim to propose any recommendation or standard. It is focussed on blind and partially sighted World Wide Web (Web) users along with others who use assistive technologies. The Web is a fast moving interdisciplinary domain in which new technologies, techniques and research is in perpetual development. It is often difficult to maintain a holistic view of new developments within the multiple domains which together make up the Web. This suggests that knowledge of the current developments and predictions of future developments are additionally important for the accessibility community. Web accessibility has previously been characterised by the correction of our past mistakes to make the current Web fulfil the original vision of access for all. New technologies were not designed with accessibility in mind and technologies that could be useful for addressing accessibility issues were not identified or adopted by the accessibility community. We wish to enable the research community to undertake preventative measures and proactively address challenges, while recognising opportunities, before they become unpreventable or require retrospective technological enhancement. This article then reviews emerging trends within the Web and Web Accessibility domains.

  19. Improving entrepreneurial opportunity recognition through web content analytics

    NASA Astrophysics Data System (ADS)

    Bakar, Muhamad Shahbani Abu; Azmi, Azwiyati

    2017-10-01

    The ability to recognize and develop an opportunity into a venture defines an entrepreneur. Research in opportunity recognition has been robust and focuses more on explaining the processes involved in opportunity recognition. Factors such as prior knowledge, cognitive and creative capabilities are shown to affect opportunity recognition in entrepreneurs. Prior knowledge in areas such as customer problems, ways to serve the market, and technology has been shows in various studies to be a factor that facilitates entrepreneurs to identify and recognize opportunities. Findings from research also shows that experienced entrepreneurs search and scan for information to discover opportunities. Searching and scanning for information has also been shown to help novice entrepreneurs who lack prior knowledge to narrow this gap and enable them to better identify and recognize opportunities. There is less focus in research on finding empirically proven techniques and methods to develop and enhance opportunity recognition in student entrepreneurs. This is important as the country pushes for more graduate entrepreneurs that can drive the economy. This paper aims to discuss Opportunity Recognition Support System (ORSS), an information support system to help especially student entrepreneurs in identifying and recognizing business opportunities. The ORSS aims to provide the necessary knowledge to student entrepreneurs to be able to better identify and recognize opportunities. Applying design research, theories in opportunity recognition are applied to identify the requirements for the support system and the requirements in turn dictate the design of the support system. The paper proposes the use of web content mining and analytics as two core components and techniques for the support system. Web content mining can mine the vast knowledge repositories available on the internet and analytics can provide entrepreneurs with further insights into the information needed to recognize

  20. Extramural Training and Career Opportunities in Aging Research.

    ERIC Educational Resources Information Center

    National Inst. on Aging (DHHS/NIH), Bethesda, MD.

    The rapid growth of the older population heightens the urgency for training in aging research. This publication outlines the opportunities for extramural research training and career development that exist within the National Institute on Aging (NIA). The NIA supports research and research training primarily through the award of grants and…

  1. The International Space Station Research Opportunities and Accomplishments

    NASA Technical Reports Server (NTRS)

    Alleyne, Camille W.

    2011-01-01

    In 2010, the International Space Station (ISS) construction and assembly was completed to become a world-class scientific research laboratory. We are now in the era of utilization of this unique platform that facilitates ground-breaking research in the microgravity environment. There are opportunities for NASA-funded research; research funded under the auspice of the United States National Laboratory; and research funded by the International Partners - Japan, Europe, Russia and Canada. The ISS facilities offer an opportunity to conduct research in a multitude of disciplines such as biology and biotechnology, physical science, human research, technology demonstration and development; and earth and space science. The ISS is also a unique resource for educational activities that serve to motivate and inspire students to pursue careers in Science, Technology, Engineering and Mathematics. Even though we have just commenced full utilization of the ISS as a science laboratory, early investigations are yielding major results that are leading to such things as vaccine development, improved cancer drug delivery methods and treatment for debilitating diseases, such as Duchenne's Muscular Dystrophy. This paper

  2. Linked Data: Opportunities and Challenges in Disability Research

    ERIC Educational Resources Information Center

    Glasson, Emma J.; Hussain, Rafat

    2008-01-01

    Background: Disability research data often exist in the form of individual records located within discrete registers that may extend across sensitive political boundaries. Method: This paper discusses the opportunities and challenges associated with using linked health and administrative data for disability research, with examples from research…

  3. Opportunities and Possibilities: Philosophical Hermeneutics and the Educational Researcher

    ERIC Educational Resources Information Center

    Agrey, Loren G.

    2014-01-01

    The opportunities that philosophical hermeneutics provide as a research tool are explored and it is shown that this qualitative research method can be employed as a valuable tool for the educational researcher. Used as an alternative to the standard quantitative approach to educational research, currently being the dominant paradigm of data…

  4. Ionospheric research opportunity

    NASA Astrophysics Data System (ADS)

    Rickel, Dwight

    1985-05-01

    Ground-based explosions have been exploited successfully in the past as a relatively controlled source for producing ionospheric disturbances. On June 25, the Defense Nuclear Agency will conduct a high explosives test on the northern section of the White Sands Missile Range. Approximately 4,800 tons of ammonium nitrate and fuel oil (ANFO) will be detonated at ground level, producing an acoustic shock wave with a surface pressure change of approximately 20 mbar at a 6 km range. This shock front will have sufficient strength to propagate into the ionosphere with at least a 10% change in the ambient pressure across the disturbance front in the lower F region. Such an ionospheric perturbation will give ionospheric researchers an excellent opportunity to investigate acoustic propagation at ionospheric heights, shock dissipation effect, the ion-neutral coupling process, acoustic-gravity wave (traveling ionospheric disturbance) generation mechanisms, and associated RF phenomena.

  5. Virtual Environments: Issues and Opportunities for Researching Inclusive Educational Practices

    NASA Astrophysics Data System (ADS)

    Sheehy, Kieron

    This chapter argues that virtual environments offer new research areas for those concerned with inclusive education. Further, it proposes that they also present opportunities for developing increasingly inclusive research processes. This chapter considers how researchers might approach researching some of these affordances. It discusses the relationship between specific features of inclusive pedagogy, derived from an international systematic literature review, and the affordances of different forms of virtual characters and environments. Examples are drawn from research in Second LifeTM (SL), virtual tutors and augmented reality. In doing this, the chapter challenges a simplistic notion of isolated physical and virtual worlds and, in the context of inclusion, between the practice of research and the research topic itself. There are a growing number of virtual worlds in which identified educational activities are taking place, or whose activities are being noted for their educational merit. These encompasses non-themed worlds such as SL and Active Worlds, game based worlds such as World of Warcraft and Runescape, and even Club Penguin, a themed virtual where younger players interact through a variety of Penguin themed environments and activities. It has been argued that these spaces, outside traditional education, are able to offer pedagogical insights (Twining 2009) i.e. that these global virtual communities have been identified as being useful as creative educational environments (Delwiche 2006; Sheehy 2009). This chapter will explore how researchers might use these spaces to investigative and create inclusive educational experiences for learners. In order to do this the chapter considers three interrelated issues: What is inclusive education?; How might inclusive education influence virtual world research? And, what might inclusive education look like in virtual worlds?

  6. Indoor chemistry: research opportunities and challenges.

    PubMed

    Nazaroff, W W; Goldstein, A H

    2015-08-01

    In this editorial, we have highlighted key research opportunities and challenges in four topical themes for indoor chemistry: human occupants as agents influencing indoor chemistry; oxidative chemistry; surface phenomena; and semivolatile organic compounds. In each case, enough prior work has been done to demonstrate the importance of the theme and to create a foundation for future studies. Extensive achievements and ongoing progress in (outdoor) atmospheric chemistry—both in the analytical methods developed and in the scientific knowledge created—also contribute to a strong foundation from which to achieve rapid research progress in this exciting new domain.

  7. Providing Opportunities for Interdisciplinary Research through Partnering two Undergraduate Research Programs: RESESS and SOARS

    NASA Astrophysics Data System (ADS)

    Pandya, R. E.; Eriksson, S. C.

    2005-12-01

    Undergraduate research provides a unique opportunity to explore scientifically novel questions, particularly those at the intersection of disciplines. This opportunity should be balanced with the need to provide the strong discipline-based training that undergraduate students require to continue their academic careers. This need for balance is especially acute for students from groups who are historically under-represented in geosciences; their status as minorities and women makes them especially vulnerable to the devaluing of their research if it isn't along traditional lines. Combining undergraduate research with a strong, diverse learning community is one way to balance the opportunity of interdisciplinary research with the need for depth of understanding in a field. In this model, students individually pursue focused research in partnership with a particular scientist as they work collaboratively across disciplines to prepare scientific papers, presentations, and posters to share the results of their research. Over time, programmatic success can even help insulate students from the risks of interdisciplinary work. Research Experience for Students in Solid Earth Science (RESESS) and Significant Opportunities in Atmospheric Science (SOARS) implement this approach. SOARS is a program with a 10-year history in the atmospheric science; RESESS is a new program focused on Solid Earth Sciences. The two currently collaborate by merging their learning communities while maintaining distinct research focuses. While still in the pilot phase of partnering, initial discussions by the student participants indicate a growing awareness of potential for cross-disciplinary collaboration. In fact, two projects, both by graduate students who have participated for multiple summers, straddle the disciplines of geology and meteorology. One project characterized dust storms in the Southwest US using remote sensing, and a second project studied wind-driven migration of sand dunes on the

  8. Research Priorities for Fertility and Conception Research as Identified by Multidisciplinary Health Care Practitioners and Researchers.

    PubMed

    Moran, Lisa J; Spencer, Laura; Russell, Darryl L; Hull, Mary Louise; Robertson, Sarah A; Varcoe, Tamara J; Davies, Michael J; Brown, Hannah M; Rodgers, Raymond J

    2016-01-13

    The Robinson Research Institute of the University of Adelaide convened a multidisciplinary group of n = 33 clinicians, researchers and representatives of government organisations on the 2 October 2014 for a workshop entitled "Promoting fertility and healthy conception. How do we generate greater reproductive health awareness?" The key aim of the workshop was to assess the body of knowledge that informs clinical practice and government policy, and to identify questions and additional information needed by health practitioners and government representatives working in the field of reproductive health and to frame future research and policy. The workshop identified topics that fell mostly into three categories: lifestyle-related, societal and biological factors. The lifestyle topics included nutrition and diet, exercise, obesity, shift work and other factors deemed to be modifiable at the level of the individual. The societal topics included discussions of matters that are structural, and resistant to change by individuals, including specific ethical issues, social disadvantage, government and educational policies. The biological factors are intrinsic physical states of the individual, and included many factors where there is a dense body of scientific knowledge which may not be readily accessible in less academic language. This workshop thus provided an opportunity to identify further actions that could be undertaken to meet the needs of diverse organisations and groups of professionals with an interest in human fertility. Since so many factors in our social and biological environment can impact fertility and preconception health, it is imperative to involve many disciplines or levels of government or societal organisations that have not traditionally been involved in this area.

  9. SSERVI Opportunities for the Next Generation of Planetary Researchers

    NASA Astrophysics Data System (ADS)

    Bailey, B. E.; Day, B. H.; Minafra, J.; Baer, J.

    2015-12-01

    NASA's Solar System Exploration Research Virtual Institute (SSERVI) was founded as a virtual institute that provides interdisciplinary research centered on the goals of its supporting directorates: NASA Science Mission Directorate (SMD) and the Human Exploration & Operations Mission Directorate (HEOMD). SSERVI consists of a diverse set of domestic teams and (currently) nine international teams, ultimately represented by greater than 75 distinct research institutions and more than 450 individual researchers and EPO specialists. The decline in funding opportunities after the termination of the Apollo missions to the Moon in the early 1970's produced a large gap in both the scientific knowledge and experience of the original lunar Apollo researchers and the resurgent group of young lunar/NEA researchers that have emerged within the last 15 years. One of SSERVI's many goals is to bridge this gap through the many networking and scientific connections made between young researchers and established planetary principle investigators. To this end, SSERVI has supported the establishment of NextGen Lunar Scientists and Engineers group (NGLSE), a group of students and early-career professionals designed to build experience and provide networking opportunities to its members. SSERVI has also created the LunarGradCon, a scientific conference dedicated solely to graduate and undergraduate students working in the lunar field. Additionally, SSERVI produces monthly seminars and bi-yearly virtual workshops that introduce students to the wide variety of exploration science being performed in today's research labs. SSERVI also brokers opportunities for domestic and international student exchange between collaborating laboratories as well as internships at our member institutions. SSERVI provides a bridge that is essential to the continued international success of scientific, as well as human and robotic, exploration.

  10. Technical Report on Research to Identify, Analyze, and Disseminate Information about Opportunities for Males and Females in Nontraditional Occupations. July 1978 through June 1979.

    ERIC Educational Resources Information Center

    Carvell, Fred; And Others

    This project was conducted to improve the quality and availability of information pertaining to opportunities in nontraditional occupations for use by teachers, counselors, and interested students. The major project objectives were (1) to review current employment patterns in California to identify nontraditional occupations; (2) to collect and…

  11. Research Opportunities on board Virgin Galactic's SpaceShipTwo

    NASA Astrophysics Data System (ADS)

    Attenborough, S.; Pomerantz, W.; Stephens, K.

    2013-09-01

    Virgin Galactic is building the world's first commercial spaceline. Our suborbital spaceflight system, pictured in Figure 1, consists of two vehicles: WhiteKnightTwo (WK2) and SpaceShipTwo (SS2). WhiteKnightTwo is a four-engine, dual-fuselage jet aircraft capable of high-altitude heavy lift missions, including, but not limited to fulfilling its role as a mothership for SpaceShipTwo, an air-launched, suborbital spaceplane capable of routinely reaching an apogee up to 110 kilometers. In conjunction, these two vehicles allow access to space and to regions of the atmosphere ranging from the troposphere to the thermosphere; additionally, they provide extended periods of microgravity in a reliable and affordable way. SpaceShipTwo, with a payload capacity of up to 1,300 lbs. (~600 kg), features payload mounting interfaces that are compatible with standard architectures such as NASA Space Shuttle Middeck Lockers, Cargo Transfer Bags, and server racks, in addition to custom structures. With the standard interface, payloads are allowed access to the large 17 inch diameter cabin windows for external observations. Each dedicated research flight will be accompanied by a Virgin Galactic Flight Test Engineer, providing an opportunity for limited in-flight interaction. In addition, tended payloads - a flight that includes the researcher and his or her payload - are also an option. At a price point that is highly competitive with parabolic aircraft and sounding rockets and significantly cheaper than orbital flights, SpaceShipTwo is a unique platform that can provide frequent and repeatable research opportunities. Suborbital flights on SpaceShipTwo offer researchers several minutes of microgravity time and views of the external environment in the upper atmosphere and in outer space. In addition to serving as an important research platform in and of itself, SpaceShipTwo also offers researchers a means to test, iterate, and calibrate experiments designed for orbital platforms

  12. Patient Engagement in Kidney Research: Opportunities and Challenges Ahead.

    PubMed

    Molnar, Amber O; Barua, Moumita; Konvalinka, Ana; Schick-Makaroff, Kara

    2017-01-01

    Patient engagement in research is increasingly recognized as an important component of the research process and may facilitate translation of research findings. To heighten awareness on this important topic, this review presents opportunities and challenges of patient engagement in research, drawing on specific examples from 4 areas of Canadian kidney research conducted by New Investigators in the Kidney Research Scientist Core Education and National Training (KRESCENT) Program. Research expertise, published reports, peer-reviewed articles, and research funding body websites. In this review, the definition, purpose, and potential benefits of patient engagement in research are discussed. Approaches toward patient engagement that may help with translation and uptake of research findings into clinical practice are highlighted. Opportunities and challenges of patient engagement are presented in both basic science and clinical research with the following examples of kidney research: (1) precision care in focal and segmental glomerulosclerosis, (2) systems biology approaches to improve management of chronic kidney disease and enhance kidney graft survival, (3) reducing the incidence of suboptimal dialysis initiation, and (4) use of patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) in kidney practice. Clinical research affords more obvious opportunities for patient engagement. The most obvious step at which to engage patients is in the setting of research priorities. Engagement at all stages of the research cycle may prove to be more challenging, and requires a detailed plan, along with funds and infrastructure to ensure that it is not merely tokenistic. Basic science research is several steps removed from the clinical application and involves complex scientific concepts, which makes patient engagement inherently more difficult. This is a narrative review of the literature that has been partly influenced by the perspectives and

  13. Equal Opportunities in Social Science Research Careers. IES Report 310.

    ERIC Educational Resources Information Center

    Court, G.; And Others

    A study examined career opportunities for women in social science research careers in the United Kingdom. Data were collected from the following sources: review of literature/data on women in social science research and their career prospects; survey of Economic and Social Research Council research centers and independent research instituted to…

  14. Opportunities and challenges for comparative effectiveness research (CER) with Electronic Clinical Data: a perspective from the EDM forum.

    PubMed

    Holve, Erin; Segal, Courtney; Hamilton Lopez, Marianne

    2012-07-01

    The Electronic Data Methods (EDM) Forum brings together perspectives from the Prospective Outcome Systems using Patient-specific Electronic data to Compare Tests and therapies (PROSPECT) studies, the Scalable Distributed Research Networks, and the Enhanced Registries projects. This paper discusses challenges faced by the research teams as part of their efforts to develop electronic clinical data (ECD) infrastructure to support comparative effectiveness research (CER). The findings reflect a set of opportunities for transdisciplinary learning, and will ideally enhance the transparency and generalizability of CER using ECD. Findings are based on 6 exploratory site visits conducted under naturalistic inquiry in the spring of 2011. Themes, challenges, and innovations were identified in the visit summaries through coding, keyword searches, and review for complex concepts. : The identified overarching challenges and emerging opportunities include: the substantial level of effort to establish and sustain data sharing partnerships; the importance of understanding the strengths and limitations of clinical informatics tools, platforms, and models that have emerged to enable research with ECD; the need for rigorous methods to assess data validity, quality, and context for multisite studies; and, emerging opportunities to achieve meaningful patient and consumer engagement and work collaboratively with multidisciplinary teams. The new infrastructure must evolve to serve a diverse set of potential users and must scale to address a range of CER or patient-centered outcomes research (PCOR) questions. To achieve this aim-to improve the quality, transparency, and reproducibility of CER and PCOR-a high level of collaboration and support is necessary to foster partnership and best practices as part of the EDM Forum.

  15. The untapped potential of genetically-engineered mouse models in chemoprevention research: Opportunities and challenges

    PubMed Central

    Abate-Shen, Cory; Brown, Powel H.; Colburn, Nancy H.; Gerner, Eugene W.; Green, Jeffery E.; Lipkin, Martin; Nelson, William G.; Threadgill, David

    2009-01-01

    Summary The past decade has witnessed the unveiling of a powerful new generation of genetically-engineered mouse (GEM) models of human cancer, which are proving to be highly effective for elucidating cancer mechanisms and interrogating novel experimental therapeutics. This new generation of GEM models are well-suited for chemoprevention research, particularly for investigating progressive stages of carcinogenesis, identifying biomarkers for early detection and intervention, and pre-clinical assessment of novel agents or combinations of agents. Here we discuss opportunities and challenges for the application of GEM models in prevention research, as well as strategies to maximize their relevance for human cancer. PMID:19138951

  16. Conducting international nursing research: challenges and opportunities.

    PubMed

    Opollo, Jackline Gloria; Opollo, Diana Alaka; Gray, Jennifer; Spies, Lori

    2014-11-01

    To describe practical experiences before, during and after gaining entry into research fields in Kenya and Uganda. Planning, conducting and implementing international research can be an arduous task. Novice researchers need practical guides to accessing international fields and mitigating challenges met in the field. The researchers conducted three different studies in two developing nations. This paper reviews challenges encountered when conducting international research. Solutions used to overcome these challenges are discussed. Establishing and maintaining effective partnerships is critical to the success of international research efforts. Researchers must be tactful, flexible and creative when handling methodological, ethical and logistical challenges encountered in settings poor in resources. International research provides opportunities for increasing dedication, building cross-cultural competence and advancing health professional practice globally. This paper contributes to nursing scholarship by highlighting the practical challenges of conducting international research. Illustrations aimed at lending insight and encouraging others to expand their dedication to conducting international research are offered.

  17. Physiotherapy Practice: Opportunities for International Collaboration on Workforce Reforms, Policy and Research.

    PubMed

    Grimmer, K; Morris, J; Kim, S; Milanese, S; Fletcher, W

    2017-07-01

    Physiotherapy or Physical Therapy (PT) is the most commonly practised allied health discipline globally. International PT workforce reforms are underway to deal with increasing patient numbers, shrinking medical and nursing workforces and lengthy waiting lists. It is timely to consider international differences in PT, with the aims of identifying opportunities for shared learning and forming stronger international alliances to support consistent and evidence-based workforce reforms. This paper synthesizes freely available information on PT training and service delivery across the UK, Australia and United States (California). The paper considers differences in roles, workplaces, training, legislation and registration, continuing professional development, and accountability. There are similarities between UK, Australia and United States (California) in many areas of PT roles, training, registration, legislation and professional practice. However, none has a standard national mechanism by which to demonstrate PT accountability, patient safety or quality care. Moreover, there are different approaches to workforce reforms. There is considerable duplication in physiotherapy governance. There are opportunities for targeted international collaborations regarding workforce reforms such as extending scope of practice, and determining and implementing internationally agreed ways of demonstrating PT accountability. The findings of this review have significant policy implications, and identify areas for collaborative research. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  18. Patient Engagement in Kidney Research: Opportunities and Challenges Ahead

    PubMed Central

    Molnar, Amber O.; Barua, Moumita; Konvalinka, Ana; Schick-Makaroff, Kara

    2017-01-01

    Purpose of Review: Patient engagement in research is increasingly recognized as an important component of the research process and may facilitate translation of research findings. To heighten awareness on this important topic, this review presents opportunities and challenges of patient engagement in research, drawing on specific examples from 4 areas of Canadian kidney research conducted by New Investigators in the Kidney Research Scientist Core Education and National Training (KRESCENT) Program. Sources of Information: Research expertise, published reports, peer-reviewed articles, and research funding body websites. Methods: In this review, the definition, purpose, and potential benefits of patient engagement in research are discussed. Approaches toward patient engagement that may help with translation and uptake of research findings into clinical practice are highlighted. Opportunities and challenges of patient engagement are presented in both basic science and clinical research with the following examples of kidney research: (1) precision care in focal and segmental glomerulosclerosis, (2) systems biology approaches to improve management of chronic kidney disease and enhance kidney graft survival, (3) reducing the incidence of suboptimal dialysis initiation, and (4) use of patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) in kidney practice. Key Findings: Clinical research affords more obvious opportunities for patient engagement. The most obvious step at which to engage patients is in the setting of research priorities. Engagement at all stages of the research cycle may prove to be more challenging, and requires a detailed plan, along with funds and infrastructure to ensure that it is not merely tokenistic. Basic science research is several steps removed from the clinical application and involves complex scientific concepts, which makes patient engagement inherently more difficult. Limitations: This is a narrative

  19. MOOCs as a Massive Research Laboratory: Opportunities and Challenges

    ERIC Educational Resources Information Center

    Diver, Paul; Martinez, Ignacio

    2015-01-01

    Massive open online courses (MOOCs) offer many opportunities for research into several topics related to pedagogical methods and student incentives. In the context of over 20 years of online learning research, we discuss lessons to be learned from observational comparisons and experiments on randomly chosen groups of students. We target two MOOCs…

  20. Identifying Homelessness among Veterans Using VA Administrative Data: Opportunities to Expand Detection Criteria.

    PubMed

    Peterson, Rachel; Gundlapalli, Adi V; Metraux, Stephen; Carter, Marjorie E; Palmer, Miland; Redd, Andrew; Samore, Matthew H; Fargo, Jamison D

    2015-01-01

    Researchers at the U.S. Department of Veterans Affairs (VA) have used administrative criteria to identify homelessness among U.S. Veterans. Our objective was to explore the use of these codes in VA health care facilities. We examined VA health records (2002-2012) of Veterans recently separated from the military and identified as homeless using VA conventional identification criteria (ICD-9-CM code V60.0, VA specific codes for homeless services), plus closely allied V60 codes indicating housing instability. Logistic regression analyses examined differences between Veterans who received these codes. Health care services and co-morbidities were analyzed in the 90 days post-identification of homelessness. VA conventional criteria identified 21,021 homeless Veterans from Operations Enduring Freedom, Iraqi Freedom, and New Dawn (rate 2.5%). Adding allied V60 codes increased that to 31,260 (rate 3.3%). While certain demographic differences were noted, Veterans identified as homeless using conventional or allied codes were similar with regards to utilization of homeless, mental health, and substance abuse services, as well as co-morbidities. Differences were noted in the pattern of usage of homelessness-related diagnostic codes in VA facilities nation-wide. Creating an official VA case definition for homelessness, which would include additional ICD-9-CM and other administrative codes for VA homeless services, would likely allow improved identification of homeless and at-risk Veterans. This also presents an opportunity for encouraging uniformity in applying these codes in VA facilities nationwide as well as in other large health care organizations.

  1. Identifying Homelessness among Veterans Using VA Administrative Data: Opportunities to Expand Detection Criteria

    PubMed Central

    Peterson, Rachel; Gundlapalli, Adi V.; Metraux, Stephen; Carter, Marjorie E.; Palmer, Miland; Redd, Andrew; Samore, Matthew H.; Fargo, Jamison D.

    2015-01-01

    Researchers at the U.S. Department of Veterans Affairs (VA) have used administrative criteria to identify homelessness among U.S. Veterans. Our objective was to explore the use of these codes in VA health care facilities. We examined VA health records (2002-2012) of Veterans recently separated from the military and identified as homeless using VA conventional identification criteria (ICD-9-CM code V60.0, VA specific codes for homeless services), plus closely allied V60 codes indicating housing instability. Logistic regression analyses examined differences between Veterans who received these codes. Health care services and co-morbidities were analyzed in the 90 days post-identification of homelessness. VA conventional criteria identified 21,021 homeless Veterans from Operations Enduring Freedom, Iraqi Freedom, and New Dawn (rate 2.5%). Adding allied V60 codes increased that to 31,260 (rate 3.3%). While certain demographic differences were noted, Veterans identified as homeless using conventional or allied codes were similar with regards to utilization of homeless, mental health, and substance abuse services, as well as co-morbidities. Differences were noted in the pattern of usage of homelessness-related diagnostic codes in VA facilities nation-wide. Creating an official VA case definition for homelessness, which would include additional ICD-9-CM and other administrative codes for VA homeless services, would likely allow improved identification of homeless and at-risk Veterans. This also presents an opportunity for encouraging uniformity in applying these codes in VA facilities nationwide as well as in other large health care organizations. PMID:26172386

  2. Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities

    PubMed Central

    Uc, Aliye; Andersen, Dana K.; Bellin, Melena D.; Bruce, Jason I.; Drewes, Asbjørn M.; Engelhardt, John F.; Forsmark, Christopher E.; Lerch, Markus M.; Lowe, Mark E.; Neuschwander-Tetri, Brent A.; O’Keefe, Stephen J.; Palermo, Tonya M.; Pasricha, Pankaj; Saluja, Ashok K.; Singh, Vikesh K.; Szigethy, Eva M.; Whitcomb, David C.; Yadav, Dhiraj; Conwell, Darwin L.

    2016-01-01

    A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to focus on research gaps and opportunities in chronic pancreatitis (CP) and its sequelae. This conference marked the 20th year anniversary of the discovery of the cationic trypsinogen (PRSS1) gene mutation for hereditary pancreatitis. The event was held on July 27, 2016, and structured into 4 sessions: (1) pathophysiology; (2) exocrine complications; (3) endocrine complications; and (4) pain. The current state of knowledge was reviewed; many knowledge gaps and research needs were identified that require further investigation. Common themes included the need to design better tools to diagnose CP and its sequelae early and reliably, identify predisposing risk factors for disease progression, develop standardized protocols to distinguish type 3c diabetes mellitus from other types of diabetes and design effective therapeutic strategies through novel cell culture technologies, animal models mimicking human disease, and pain management tools. Gene therapy and cystic fibrosis conductance regulator (CFTR) potentiators as possible treatments for CP were discussed. Importantly, the need for chronic pancreatitis endpoints and intermediate targets for future drug trials was emphasized. PMID:27748719

  3. Opportunities for research to improve employment for people with spinal cord injuries.

    PubMed

    Frieden, L; Winnegar, A J

    2012-05-01

    This paper reviews the literature pertaining to the employment of people who experience spinal cord injury (SCI) in the United States and recommending future research. The literature was reviewed with search terms such as SCI, employment, working from home and telework using databases in EBSCO, including Academic Search Complete and the American Psychological Association’s databases. Literature and findings on key factors related to employment illustrate the multiple dimensions of work environments, and health demands, that effect employment outcomes for people with SCI. Employment is important for people with SCI and valued in society. The literature reviewed indicates that researchers understand the work demands for people with SCI and may help to identify suitable supports, training and job opportunities. There remains a need for research focus on understanding future employment demands, necessary work skills, differing work environments and methods for increasing and preserving employment.

  4. Identifying research priorities for health care priority setting: a collaborative effort between managers and researchers

    PubMed Central

    Smith, Neale; Mitton, Craig; Peacock, Stuart; Cornelissen, Evelyn; MacLeod, Stuart

    2009-01-01

    Background To date there has been relatively little published about how research priorities are set, and even less about methods by which decision-makers can be engaged in defining a relevant and appropriate research agenda. We report on a recent effort in British Columbia to have researchers and decision-makers jointly establish an agenda for future research into questions of resource allocation. Methods The researchers enlisted decision-maker partners from each of British Columbia's six health authorities. Three forums were held, at which researchers and decision-makers from various levels in the health authorities considered possible research areas related to three key focus areas: (1) generation and use of decision criteria and measurement of 'benefit' against such criteria; (2) identification of so-called 'disinvestment' opportunities; and (3) evaluation of the effectiveness of priority setting procedures. Detailed notes were taken from each forum and synthesized into a set of qualitative themes. Results Forum participants suggested that future research into healthcare priority setting would benefit from studies that were longitudinal, comparative, and/or interdisciplinary. As well, participants identified two broad theme areas in which specific research projects were deemed desirable. First, future research might usefully consider how formal priority setting and resource allocation projects are situated within a larger organizational and political context. Second, additional research efforts should be devoted to better understanding and improving the actual implementation of priority setting frameworks, particularly with respect to issues of change management and the resolution of impediments to action on recommendations for resource allocation. Conclusion We were able to validate the importance of initial areas posed to the group and observed emergence of additional concerns and directions of critical importance to these decision-makers at this time. It is

  5. Opportunities and Challenges for Interdisciplinary Research and Education

    ERIC Educational Resources Information Center

    Lin, Henry

    2008-01-01

    Interdisciplinary research and education (IDRE) holds center stage in current academic discussions. Despite the widespread agreement on the promises of IDRE, barriers for effective IDRE implementation remain significant. This study explored the opportunities and challenges of IDRE in integrated soil and water sciences at the Pennsylvania State…

  6. Using the Electronic Health Record in Nursing Research: Challenges and Opportunities.

    PubMed

    Samuels, Joanne G; McGrath, Robert J; Fetzer, Susan J; Mittal, Prashant; Bourgoine, Derek

    2015-10-01

    Changes in the patient record from the paper to the electronic health record format present challenges and opportunities for the nurse researcher. Current use of data from the electronic health record is in a state of flux. Novel data analytic techniques and massive data sets provide new opportunities for nursing science. Realization of a strong electronic data output future relies on meeting challenges of system use and operability, data presentation, and privacy. Nurse researchers need to rethink aspects of proposal development. Joining ongoing national efforts aimed at creating usable data output is encouraged as a means to affect system design. Working to address challenges and embrace opportunities will help grow the science in a way that answers important patient care questions. © The Author(s) 2015.

  7. Disrupting Improvised Explosive Device Terror Campaigns: Basic Research Opportunities

    DTIC Science & Technology

    2008-01-01

    2008 2. REPORT TYPE 3. DATES COVERED 00-00-2008 to 00-00-2008 4. TITLE AND SUBTITLE Disrupting Improvised Explosive Device Terror Campaigns... Explosive Device Terror Campaigns: Basic Research Opportunities A WORKSHOP REPORT Committee on Defeating Improvised Explosive Devices...iv v COMMITTEE ON DEFEATING IMPROVISED EXPLOSIVE DEVICES: BASIC RESEARCH TO INTERRUPT THE IED DELIVERY CHAIN Chairperson

  8. Opportunities and Benefits as Determinants of the Direction of Scientific Research*

    PubMed Central

    Bhattacharya, Jay; Packale, Mikko

    2017-01-01

    Scientific research and private-sector technological innovation differ in objectives, constraints, and organizational forms. Scientific research may thus not be driven by the direct practical benefit to others in the way that private-sector innovation is. Alternatively, some–yet largely unexplored-mechanisms drive the direction of scientific research to respond to the expected public benefit. We test these two competing hypotheses of scientific research. This is important because any coherent specification of what constitutes the socially optimal allocation of research requires that scientists take the public practical benefit of their work into account in setting their agenda. We examine whether the composition of medical research responds to changes in disease prevalence, while accounting for the quality of available research opportunities. We match biomedical publications data with disease prevalence data and develop new methods for estimating the quality of research opportunities from textual information and structural productivity parameters. PMID:21683461

  9. Internet research: an opportunity to revisit classic ethical problems in behavioral research.

    PubMed

    Pittenger, David J

    2003-01-01

    The Internet offers many new opportunities for behavioral researchers to conduct quantitative and qualitative research. Although the ethical guidelines of the American Psychological Association generalize, in part, to research conducted through the Internet, several matters related to Internet research require further analysis. This article reviews several fundamental ethical issues related to Internet research, namely the preservation of privacy, the issuance of informed consent, the use of deception and false feedback, and research methods. In essence, the Internet offers unique challenges to behavioral researchers. Among these are the need to better define the distinction between private and public behavior performed through the Internet, ensure mechanisms for obtaining valid informed consent from participants and performing debriefing exercises, and verify the validity of data collected through the Internet.

  10. Evidence and Interpretation in Language Learning Research: Opportunities for Collaboration with Computational Linguistics

    ERIC Educational Resources Information Center

    Meurers, Detmar; Dickinson, Markus

    2017-01-01

    This article discusses two types of opportunities for interdisciplinary collaboration between computational linguistics (CL) and language learning research. We target the connection between data and theory in second language (L2) research and highlight opportunities to (a) enrich the options for obtaining data and (b) support the identification…

  11. NIH Common Fund - Disruptive Proteomics Technologies - Challenges and Opportunities | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    This Request for Information (RFI) is directed toward determining how best to accelerate research in disruptive proteomics technologies. The Disruptive Proteomics Technologies (DPT) Working Group of the NIH Common Fund wishes to identify gaps and opportunities in current technologies and methodologies related to proteome-wide measurements.  For the purposes of this RFI, “disruptive” is defined as very rapid, very significant gains, similar to the "disruptive" technology development that occurred in DNA sequencing technology.

  12. Multilateral Research Opportunities in Ground Analogs

    NASA Technical Reports Server (NTRS)

    Corbin, Barbara J.

    2015-01-01

    The global economy forces many nations to consider their national investments and make difficult decisions regarding their investment in future exploration. International collaboration provides an opportunity to leverage other nations' investments to meet common goals. The Humans In Space Community shares a common goal to enable safe, reliable, and productive human space exploration within and beyond Low Earth Orbit. Meeting this goal requires efficient use of limited resources and International capabilities. The International Space Station (ISS) is our primary platform to conduct microgravity research targeted at reducing human health and performance risks for exploration missions. Access to ISS resources, however, is becoming more and more constrained and will only be available through 2020 or 2024. NASA's Human Research Program (HRP) is actively pursuing methods to effectively utilize the ISS and appropriate ground analogs to understand and mitigate human health and performance risks prior to embarking on human exploration of deep space destinations. HRP developed a plan to use ground analogs of increasing fidelity to address questions related to exploration missions and is inviting International participation in these planned campaigns. Using established working groups and multilateral panels, the HRP is working with multiple Space Agencies to invite International participation in a series of 30- day missions that HRP will conduct in the US owned and operated Human Exploration Research Analog (HERA) during 2016. In addition, the HRP is negotiating access to Antarctic stations (both US and non-US), the German :envihab and Russian NEK facilities. These facilities provide unique capabilities to address critical research questions requiring longer duration simulation or isolation. We are negotiating release of international research opportunities to ensure a multilateral approach to future analog research campaigns, hoping to begin multilateral campaigns in the

  13. Opportunities and benefits as determinants of the direction of scientific research.

    PubMed

    Bhattacharya, Jay; Packalen, Mikko

    2011-07-01

    Scientific research and private-sector technological innovation differ in objectives, constraints, and organizational forms. Scientific research may thus not be driven by the direct practical benefit to others in the way that private-sector innovation is. Alternatively, some - yet largely unexplored - mechanisms drive the direction of scientific research to respond to the expected public benefit. We test these two competing hypotheses of scientific research. This is important because any coherent specification of what constitutes the socially optimal allocation of research requires that scientists take the public practical benefit of their work into account in setting their agenda. We examine whether the composition of medical research responds to changes in disease prevalence, while accounting for the quality of available research opportunities. We match biomedical publications data with disease prevalence data and develop new methods for estimating the quality of research opportunities from textual information and structural productivity parameters. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. Enhancing Opportunities in Job Markets: Summary of Research and Recommendations for Policy. Final Report.

    ERIC Educational Resources Information Center

    Pascal, Anthony N.

    As a result of research conducted for the Office of Economic Opportunity (OEO) regarding opportunities in the job market, this report includes: (1) a description of the policy and program recommendations suggested by research findings, and (2) a synthesis of research findings applicable to OEO, particularly highlighting their relevance to…

  15. The Cystic Fibrosis Database: Content and Research Opportunities.

    ERIC Educational Resources Information Center

    Shaw, William M., Jr.; And Others

    1991-01-01

    Describes the files contained in the Cystic Fibrosis (CF) database and discusses educational and research opportunities using this database. Topics discussed include queries, evaluating the relevance of items retrieved, and use of the database in an online searching course in the School of Information and Library Science at the University of North…

  16. Global Vaccine and Immunization Research Forum: Opportunities and challenges in vaccine discovery, development, and delivery.

    PubMed

    Ford, Andrew Q; Touchette, Nancy; Hall, B Fenton; Hwang, Angela; Hombach, Joachim

    2016-03-18

    The World Health Organization, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the Bill & Melinda Gates Foundation convened the first Global Vaccine and Immunization Research Forum (GVIRF) in March 2014. This first GVIRF aimed to track recent progress of the Global Vaccine Action Plan research and development agenda, identify opportunities and challenges, promote partnerships in vaccine research, and facilitate the inclusion of all stakeholders in vaccine research and development. Leading scientists, vaccine developers, and public health officials from around the world discussed scientific and technical challenges in vaccine development, research to improve the impact of immunization, and regulatory issues. This report summarizes the discussions and conclusions from the forum participants. Copyright © 2016. Published by Elsevier Ltd.. All rights reserved.

  17. Manning Army Equal Opportunity Officer Positions

    DTIC Science & Technology

    2013-03-01

    equality , and other social dynamics. This long overdue initiative identified organizational and cultural impediments that had essentially prevented...Manning Army Equal Opportunity Officer Positions by Colonel Angela M. Odom United States Army...TYPE STRATEGY RESEARCH PROJECT .33 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Manning Army Equal Opportunity Officer Positions 5a

  18. Grant opportunities for academic research and training

    USGS Publications Warehouse

    ,

    2016-08-30

    As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that affect our lives. Grant opportunities for researchers and faculty to participate in USGS science through the engagement of students are available in the selected programs described in this publication.

  19. Next Generation Scientists - Creating opportunities for high school students through astronomical research

    NASA Astrophysics Data System (ADS)

    Kelly, Madeline; Cebulla, Hannah; Powers, Lynn

    2015-01-01

    Through various opportunities and experiences with extracurricular scientific research, primarily astronomical research with programs like NASA/IPAC Teacher Archive Research Project (NITARP), and the Mars Exploration Student Data Teams (MESDT), we have noticed a change in our learning style, career path, and general outlook on the scientific community that we strongly believe could also be added to the lives of many other high school students given similar opportunities. The purpose of our poster is to emphasize the importance of granting high school students opportunities to explore different styles and methods of learning. We believe that although crucial, a basic high school education is not enough to expose young adults to the scientific community and create enough interest for a career path. As a result, we wish to show that more of these programs and opportunities should be offered to a greater number of students of all ages, allowing them to explore their passions, develop their understanding of different fields, and determine the paths best suited to their interests. Within our poster, we will emphasize how these programs have specifically impacted our lives, what we hope to see in the future, and how we hope to attain the growth of such opportunities. We include such proposals as; increasing outreach programs, expanding the exposure of young students to the sciences, both in the classroom and out, allowing high school students to participate in active scientific research, and involving students in hands-on activities/experiments within school clubs, the classroom, at home, or at local events. Spreading these opportunities to directly interact with the sciences in similar manners as that of professional scientists will allow students to discover their interests, realize what being a scientist truly entails, and allow them to take the first steps into following their career paths.

  20. Knowledge Brokers in the Making: Opportunities to Connect Researchers and Stakeholders

    NASA Astrophysics Data System (ADS)

    Pennell, K. G.; Pennell, M. C.

    2014-12-01

    Environmental science and engineering graduate students often lack training on how to communicate with policy decision makers who are grappling with questions to which research is responding. They communicate directly with mutual experts, but are many times unable to engage with non-experts about their research, thereby limiting the reach and impact of their findings. This presentation highlights opportunities within environmental science and engineering research to create opportunities for researchers to hone skills as knowledge brokers, so they learn ways to meaningfully engage with a range of stakeholders. A knowledge broker is an individual who connects scientific experts and relevant stakeholders with meaningful and useable information. Recognizing that information must flow in multiple directions, the knowledge broker must quickly and effectively translate needs and questions using established relationships. It is these relationships, as well as the synthesis of scientific knowledge into useable information, on which the success of the knowledge broker lies. Using lessons learned, as well as communication science theory related to knowledge brokering, this presentation highlights training opportunities for knowledge brokers who are primarily educated in science and engineering fields, yet seek to engage with societally relevant stakeholders. We present case study examples of knowledge brokering within two large multi-disciplinary research centers. These centers provide unique experiences for researchers to build relationships with stakeholders, so that the scientific experts not only create novel research within their specific discipline, but also inform policy decision makers, community members and regulatory officials.

  1. Leveraging Epidemiology and Clinical Studies of Cancer Outcomes: Recommendations and Opportunities for Translational Research

    PubMed Central

    2013-01-01

    As the number of cancer survivors continues to grow, research investigating the factors that affect cancer outcomes, such as disease recurrence, risk of second malignant neoplasms, and the late effects of cancer treatments, becomes ever more important. Numerous epidemiologic studies have investigated factors that affect cancer risk, but far fewer have addressed the extent to which demographic, lifestyle, genomic, clinical, and psychosocial factors influence cancer outcomes. To identify research priorities as well as resources and infrastructure needed to advance the field of cancer outcomes and survivorship research, the National Cancer Institute sponsored a workshop titled “Utilizing Data from Cancer Survivor Cohorts: Understanding the Current State of Knowledge and Developing Future Research Priorities” on November 3, 2011, in Washington, DC. This commentary highlights recent findings presented at the workshop, opportunities to leverage existing data, and recommendations for future research, data, and infrastructure needed to address high priority clinical and research questions. Multidisciplinary teams that include epidemiologists, clinicians, biostatisticians, and bioinformaticists will be essential to facilitate future cancer outcome studies focused on improving clinical care of cancer patients, identifying those at high risk of poor outcomes, and implementing effective interventions to ultimately improve the quality and duration of survival. PMID:23197494

  2. Educational Opportunities. Tackling Ethnic, Class and Gender Inequality through Research.

    ERIC Educational Resources Information Center

    Driessen, Geert, Ed.; Jungbluth, Paul, Ed.

    This collection presents a cross section of research into the theme of equal opportunities in education in the Netherlands. The majority of articles are on the Dutch situation, which resembles that of other countries in many respects. Contributions include: (1) "Educational Inequality Research in the Netherlands. Conditions, Constraints and…

  3. Understanding and managing the food-energy-water nexus - opportunities for water resources research

    NASA Astrophysics Data System (ADS)

    Cai, Ximing; Wallington, Kevin; Shafiee-Jood, Majid; Marston, Landon

    2018-01-01

    Studies on the food, energy, and water (FEW) nexus lay a shared foundation for researchers, policy makers, practitioners, and stakeholders to understand and manage linked production, utilization, and security of FEW systems. The FEW nexus paradigm provides the water community specific channels to move forward in interdisciplinary research where integrated water resources management (IWRM) has fallen short. Here, we help water researchers identify, articulate, utilize, and extend our disciplinary strengths within the broader FEW communities, while informing scientists in the food and energy domains about our unique skillset. This paper explores the relevance of existing and ongoing scholarship within the water community, as well as current research needs, for understanding FEW processes and systems and implementing FEW solutions through innovations in technologies, infrastructures, and policies. Following the historical efforts in IWRM, hydrologists, water resources engineers, economists, and policy analysts are provided opportunities for interdisciplinary studies among themselves and in collaboration with energy and food communities, united by a common path to achieve sustainability development goals.

  4. Collaborative Oceanographic Research Opportunities with Schmidt Ocean Institute

    NASA Astrophysics Data System (ADS)

    Zykov, V.

    2014-12-01

    Schmidt Ocean Institute (http://www.schmidtocean.org/) was founded by Dr. Eric Schmidt and Wendy Schmidt in 2009 to support frontier oceanographic research and exploration to expand the understanding of the world's oceans through technological advancement, intelligent, data-rich observation and analysis, and open sharing of information. Schmidt Ocean Institute operates a state-of-the-art globally capable research vessel Falkor (http://www.schmidtocean.org/story/show/47). After two years of scientific operations in the Atlantic Ocean, Gulf of Mexico, Caribbean, Eastern and Central Pacific, R/V Falkor is now preparing to support research in the Western Pacific and Eastern Indian Oceans in 2015 and 2016. As part of the long term research program development for Schmidt Ocean Institute, we aim to identify initiatives and projects that demonstrate strong alignment with our strategic interests. We focus on scientific opportunities that highlight effective use of innovative technologies to better understand the oceans, such as, for example, research enabled with remotely operated and autonomous vehicles, acoustics, in-situ sensing, telepresence, etc. Our technology-first approach to ocean science gave rise to infrastructure development initiatives, such as the development of a new full ocean depth Hybrid Remotely Operated Vehicle, new 6000m scientific Autonomous Underwater Vehicle, live HD video streaming from the ship to YouTube, shipboard high performance supercomputing, etc. We also support projects focusing on oceanographic technology research and development onboard R/V Falkor. We provide our collaborators with access to all of R/V Falkor's facilities and instrumentation in exchange for a commitment to make the resulting scientific data openly available to the international oceanographic community. This presentation aims to expand awareness about the interests and capabilities of Schmidt Ocean Institute and R/V Falkor among our scientific audiences and further

  5. Data Sharing in Interpretive Engineering Education Research: Challenges and Opportunities from a Research Quality Perspective

    ERIC Educational Resources Information Center

    Walther, Joachim; Sochacka, Nicola W.; Pawley, Alice L.

    2016-01-01

    This article explores challenges and opportunities associated with sharing qualitative data in engineering education research. This exploration is theoretically informed by an existing framework of interpretive research quality with a focus on the concept of Communicative Validation. Drawing on practice anecdotes from the authors' work, the…

  6. Biomimetic materials in the utility industry: A program plan for research opportunities, volume 2. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richman, R.H.; McNaughton, W.P.

    1996-09-01

    This report is the second of a two-volume set addressing the state-of-the-art and outlook for the application of biomimetic materials. The first volume examined achievements in mimicking novel aspects of biological systems in five broad categories: (1) Mimicking of Natural Material Designs, (2) Biomimetic Materials Processing, (3) Artificial Photosynthesis, (4) Biomimetic Molecular Electronics, and (5) Biomimetic Catalysis. Each topic was examined as to current activities and approaches, key aspects, unresolved issues, and implications for the power industry. Key researchers, their organizations, the main thrusts of investigation, achievements, and funding agencies were also summarized. This volume highlights opportunities for future researchmore » activities in biomimetics that could be valuable to the U.S. utility industry. Nineteen specific research projects have been identified. These opportunities are outlined in four classes: (1) technology awareness, (2) modeling and experimental studies, (3) state-of-the-art and outlook studies: developing experimental plans, and (4) concept feasibility studies.« less

  7. Exploration of Textual Interactions in CALL Learning Communities: Emerging Research and Opportunities

    ERIC Educational Resources Information Center

    White, Jonathan R.

    2017-01-01

    Computer-assisted language learning (CALL) has greatly enhanced the realm of online social interaction and behavior. In language classrooms, it allows the opportunity for students to enhance their learning experiences. "Exploration of Textual Interactions in CALL Learning Communities: Emerging Research and Opportunities" is an ideal…

  8. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

  9. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

  10. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

  11. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

  12. 42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

  13. Qualitative Experimentation, Local Generalizability, and Other Oxymoronic Opportunities for Educated Researchers

    ERIC Educational Resources Information Center

    Brooks, Gordon P.

    2011-01-01

    As lines between research paradigms continue to blur with the ever-increasing popularity of mixed methods research, there are useful, and occasionally oxymoronic, opportunities for educational researchers to juxtapose tools from opposing methods. The gold standard is just not possible in so much of what we do with small-scale research, nor is it…

  14. Comprehensive Opportunities for Research and Teaching Experience (CORTEX): A mentorship program.

    PubMed

    Zuzuárregui, José Rafael P; Hohler, Anna D

    2015-06-09

    We developed a program to promote medical student interest in pursuing a career in neurology. This program focuses on medical student mentorship. It also offers opportunities in teaching and clinical research in order to provide students with marketable skills for an academic career in neurology. Through this program, students are provided with guidance in developing a fourth-year clerkship schedule and an application package for residency programs. Students are involved and mentored in clinical research. Opportunities are also provided for students to teach their peers, with sessions focusing on examination preparation. Since the implementation of this program in 2010, the number of students entering into the field of neurology from our institution significantly increased from 14 students between 2006 and 2010, to 30 students between 2011 and 2014 (p < 0.05). Medical student research productivity increased from 7 publications during 2006-2010, to 22 publications, 14 poster presentations, and a book chapter after implementation of this program in 2010 (p < 0.05). In this mentoring program, students are prepared for residency application and provided with research and teaching opportunities. Students develop a highly desirable academic skill set for residency and have matched at top-ranked institutions. This program has been successful in improving student productivity in clinical research and garnering student interest in neurology. © 2015 American Academy of Neurology.

  15. NUL Research History: Opportunity Magazine

    ERIC Educational Resources Information Center

    Urban League Review, 1976

    1976-01-01

    Discusses an official publication of the National Urban League, "Opportunity: Journal of Negro Life," first published in 1923. The purpose of "Opportunity" was to objectively present facts of Negro life through an analysis of social questions, to provide a basis of understanding and to encourage interracial cooperation in the…

  16. Microgravity research opportunities for the 1990s

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Committee on Microgravity Research (CMGR) was made a standing committee of the Space Studies Board (SSB) and charged with developing a long-range research strategy. The scientific disciplines contained within the microgravity program, and covered in this report, include fluid mechanics and transport phenomena, combustion, biological sciences and biotechnology, materials science, and microgravity physics. The purpose of this report is to recommend means to accomplish the goal of advancing science and technology in each of the component disciplines. Microgravity research should be aimed at making significant impacts in each discipline emphasized. The conclusions and recommendations presented in this report fall into five categories: (1) overall goals for the microgravity research program; (2) general priorities among the major scientific disciplines affected by gravity; (3) identification of the more promising experimental challenges and opportunities within each discipline; (4) general scientific recommendations that apply to all microgravity-related disciplines; and (5) recommendations concerning administrative policies and procedures that are essential to the conduct of excellent laboratory science.

  17. Identifying research needs for wheelchair transfers in the built environment.

    PubMed

    Crytzer, Theresa Marie; Cooper, Rory; Jerome, Genevieve; Koontz, Alicia

    2017-02-01

    The purpose of this study is to describe the results of focus groups held during the Independent Wheelchair Transfer (IWT) Workgroup. The aims were to facilitate exchange of ideas on (1) the impact of the built environment on the wheelchair transfer process within the community (i.e. moving from wheelchair to and from other surfaces (e.g. furniture, toilet seat, bath bench, car seat) to participate in daily activities), (2) wheelchair users' needs during transfers in the built environment, and (3) future research directions. Live web-based conferencing using Adobe Connect technology (Clarix Technologies, Inc., Pittsford, NY) was utilized to conduct three focus groups composed of experts in the field of assistive technology. Investigators independently reviewed focus group meeting transcripts and used qualitative methods to identify main themes. Thirty-one experts in assistive technology and related fields participated in focus groups. Nine main themes were found including the effect of transfer skills training, space considerations in the built environment, wheelchair configuration, and the interaction between the built environment, user preferences, and transfer techniques. All groups raised issues about the transfer process in areas of the built environment with limited access, the effect of wheelchair users' transfer techniques, and user preferences during transfers. The area of independent transfers is multi-faceted and several factors require consideration when contemplating environmental changes to improve accessibility for wheelchair users. Obvious opportunity exists for research which could lead to advances in transfer technology, environments, and techniques for wheelchair users. Implications for Rehabilitation Tremendous opportunities for research collaborations in the field of assistive technology: To develop new terminology to describe wheelchair transfers. To improve the design of the built environment for wheelchair users. To investigate wheelchair

  18. Emerging Science and Research Opportunities for Metals and Metallic Nanostructures: A Report on the NSF MMN Workshop

    NASA Astrophysics Data System (ADS)

    Pollock, Tresa; Handwerker, Carol

    In the next decade, fundamental research in metals and metallic nanostructures (MMN) has the potential to continue to transform science into innovative materials, devices, and systems. This talk summarizes the findings of a workshop to identify emerging and potentially transformative research areas in MMN. The metals and metallic nanostructures (MMNs) workshop aimed to identify significant research trends, scientific fundamentals, and recent breakthroughs that can enable new or enhanced MMN performance, either alone or in a more complex materials system, for a wide range of applications. Additionally, the role that MMN research can play in high-priority research and development (R&D) areas such as the U.S. Materials Genome Initiative, the National Nanotechnology Initiative, the Advanced Manufacturing Initiative, and other similar initiatives that exist internationally was assessed. The workshop also addressed critical issues related to materials research instrumentation and the cyberinfrastructure for materials science research and education, as well as science, technology, engineering, and mathematics (STEM) workforce development, with emphasis on the United States but with an appreciation that similar challenges and opportunities for the materials community exist internationally.

  19. A review of NCI's extramural grant portfolio: identifying opportunities for future research in genes and environment in cancer.

    PubMed

    Ghazarian, Armen A; Simonds, Naoko I; Bennett, Kelly; Pimentel, Camilla B; Ellison, Gary L; Gillanders, Elizabeth M; Schully, Sheri D; Mechanic, Leah E

    2013-04-01

    Genetic and environmental factors jointly influence cancer risk. The NIH has made the study of gene-environment (GxE) interactions a research priority since the year 2000. To assess the current status of GxE research in cancer, we analyzed the extramural grant portfolio of the National Cancer Institute (NCI) from Fiscal Years 2007 to 2009. Publications attributed to selected grants were also evaluated. From the 1,106 research grants identified in our portfolio analysis, a random sample of 450 grants (40%) was selected for data abstraction; of these, 147 (33%) were considered relevant. The most common cancer type was breast (20%, n = 29), followed by lymphoproliferative (10%, n = 14), colorectal (9%, n = 13), melanoma/other skin (9%, n = 13), and lung/upper aerodigestive tract (8%, n = 12) cancers. The majority of grants were studies of candidate genes (68%, n = 100) compared with genome-wide association studies (GWAS) (8%, n = 12). Approximately one-third studied environmental exposures categorized as energy balance (37%, n = 54) or drugs/treatment (29%, n = 43). From the 147 relevant grants, 108 publications classified as GxE or pharmacogenomic were identified. These publications were linked to 37 of the 147 grant applications (25%). The findings from our portfolio analysis suggest that GxE studies are concentrated in specific areas. There is room for investments in other aspects of GxE research, including, but not limited to developing alternative approaches to exposure assessment, broadening the spectrum of cancer types investigated, and conducting GxE within GWAS. This portfolio analysis provides a cross-sectional review of NCI support for GxE research in cancer.

  20. Innovative Approaches in Chronic Disease Management: Health Literacy Solutions and Opportunities for Research Validation.

    PubMed

    Villaire, Michael; Gonzalez, Diana Peña; Johnson, Kirby L

    2017-01-01

    This chapter discusses the need for innovative health literacy solutions to combat extensive chronic disease prevalence and costs. The authors explore the intersection of chronic disease management and health literacy. They provide specific examples of successful health literacy interventions for managing several highly prevalent chronic diseases. This is followed by suggestions on pairing research and practice to support effective disease management programs. In addition, the authors discuss strategies for collection and dissemination of knowledge gained from collaborations between researchers and practitioners. They identify current challenges specific to disseminating information from the health literacy field and offer potential solutions. The chapter concludes with a brief look at future directions and organizational opportunities to integrate health literacy practices to address the need for effective chronic disease management.

  1. Identifying opportunities to enhance environmental cleaning in 23 acute care hospitals .

    PubMed

    Carling, P C; Parry, M F; Von Beheren, S M

    2008-01-01

    The quality of environmental hygiene in hospitals is under increasing scrutiny from both healthcare providers and consumers because the prevalence of serious infections due to multidrug-resistant pathogens has reached alarming levels. On the basis of the results from a small number of hospitals, we undertook a study to evaluate the thoroughness of disinfection and cleaning in the patient's immediate environment and to identify opportunities for improvement in a diverse group of acute care hospitals. Prospective multicenter study to evaluate the thoroughness of terminal room cleaning in hospitals using a novel targeting method to mimic the surface contamination of objects in the patient's immediate environment. Twenty-three acute care hospitals. The overall thoroughness of terminal cleaning, expressed as a percentage of surfaces evaluated, was 49% (range for all 23 hospitals, 35%-81%). Despite the tight clustering of overall cleaning rates in 21 of the hospitals, there was marked variation within object categories, which was particularly notable with respect to the cleaning of toilet handholds, bedpan cleaners, light switches, and door knobs (mean cleaning rates, less than 30%; institutional ranges, 0%-90%). Sinks, toilet seats, and tray tables, in contrast, were consistently relatively well cleaned (mean cleaning rates, over 75%). Patient telephones, nurse call devices, and bedside rails were inconsistently cleaned. We identified significant opportunities in all participating hospitals to improve the cleaning of frequently touched objects in the patient's immediate environment. The information obtained from such assessments can be used to develop focused administrative and educational interventions that incorporate ongoing feedback to the environmental services staff, to improve cleaning and disinfection practices in healthcare institutions.

  2. Basic research for the future: Opportunities in microbiology for the coming decade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Payne, W.J.

    1996-12-31

    Not since Leeuwenhoek reported finding {open_quotes}animalcules{close_quotes} in a variety of natural materials have research opportunities in microbiology looked so promising. Researchers have developed methods to analyze the historic and evolutionary progression of bacteria, fungi, and viruses. The significance of the remarkable diversity found in the microbial realm is just beginning to emerge. Biotechnology companies are exploiting microorganisms in remarkable ways. Seemingly new, devastating pathogens have appeared and {open_quotes}old{close_quotes} pathogens have become resistant to antiobiotics. All these factors serve to invigorate interest in microbiology. Seldom have the challenges seemed more intense or more exciting. Recognizing the significance of these issues, themore » American Academy of Microbiology convened a colloquium of experts in the microbiological sciences May 4-7, 1996, in Washington, D.C. The colloquim sought primarily to identify those research areas most clearly deserving future attention, those most likely to provide optimal return on scientific and monetary investment, and those offering the greatest promise for solving critical problems over the coming decade.« less

  3. Higher Education Research of Intercollegiate Athletics: A Missed Opportunity

    ERIC Educational Resources Information Center

    Hirko, Scott

    2008-01-01

    This study demonstrated the lack of research on college sports in significant higher education academic journals and conferences. Higher education peer-reviewed journals and conferences were considered the most common areas to reasonably measure the frequency of opportunity for national dialogue among scholars. The results found one percent of…

  4. The Airborne Research Instrumentation Testing Opportunity (ARISTO)

    NASA Astrophysics Data System (ADS)

    Wolff, C.; Romashkin, P.; Lussier, L.; Baeuerle, B.; Stith, J. L.

    2016-12-01

    In 2015 the National Science Foundation (NSF) began a program to sponsor an annual flight campaign on one of its research aircraft (the C-130 and GV) operated by the National Center for Atmospheric Research (NCAR). The aircraft are managed by the Research Aviation Facility (RAF), which is part of the Earth Observing Laboratory (EOL) and responsible for planning and executing the campaigns. The purpose of this program, known as the Airborne Research Instrumentation Testing Opportunity or ARISTO, is to provide regular flight test opportunities for newly developed or highly modified instruments as part of their development effort. The NSF community has expressed a strong desire for regularly scheduled flight-testing programs to be able to test instrumentation, data systems, inlets, and software. ARISTO allows this testing in a low-pressure environment where any issues or problems will not affect the scientific goals of a large-scale field campaign. For this reason it is also a good experience for students who may be learning about the operation of an instrument or have not had previous exposure to a field project. They are also able to contribute to flight planning exercises and gain experience in acting as an instrument scientist during the program. A goal of the program is to incorporate students into the project operations to prepare the next generation of airborne researchers. ARISTO is conducted at the Research Aviation Facility at Rocky Mountain Metropolitan Airport in Broomfield, Colorado. The flight campaign consists of 20 flight hours, spread over three weeks. Flights are planned to allow the ARISTO participants to successfully test their instruments based on requirements they described in the initial application. Due to the limited hours most flights are focused in and around Colorado, though some have gone as far as Oklahoma and the Pacific Northwest to find the right conditions to meet testing requirements. Two ARISTO campaigns were successfully completed

  5. Integrating Opportunities: Applied Interdisciplinary Research in Undergraduate Geography and Geology Education

    ERIC Educational Resources Information Center

    Viertel, David C.; Burns, Diane M.

    2012-01-01

    Unique integrative learning approaches represent a fundamental opportunity for undergraduate students and faculty alike to combine interdisciplinary methods with applied spatial research. Geography and geoscience-related disciplines are particularly well-suited to adapt multiple methods within a holistic and reflective mentored research paradigm.…

  6. Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

    PubMed

    Uzuner, Halil; Bauer, Rudolf; Fan, Tai-Ping; Guo, De-An; Dias, Alberto; El-Nezami, Hani; Efferth, Thomas; Williamson, Elizabeth M; Heinrich, Michael; Robinson, Nicola; Hylands, Peter J; Hendry, Bruce M; Cheng, Yung-Chi; Xu, Qihe

    2012-04-10

    to integrative medicine, concerned on the impact of regulation of TCM practitioners and emphasised intersectoral collaborations in funding TCM research, especially clinical trials. The GP-TCM consortium made great efforts to address some fundamental issues in TCM research, including developing guidelines, as well as identifying priorities, challenges and opportunities. These consortium guidelines and consensus will need dissemination, validation and further development through continued interregional, interdisciplinary and intersectoral collaborations. To promote this, a new consortium, known as the GP-TCM Research Association, is being established to succeed the 3-year fixed term FP7 GP-TCM consortium and will be officially launched at the Final GP-TCM Congress in Leiden, the Netherlands, in April 2012. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  7. Research opportunities and needs in the taiga of Alaska.

    Treesearch

    Austin E. Helmers; Charles T. Cushwa

    1973-01-01

    An appraisal of taiga (the northern forests of interior Alaska) environment research opportunities and needs was made based upon accomplishments since Alaskan statehood, current involvement of citizens in resource issues, information needs incident to the National Environmental Policy Act of 1969, and needs of new resource managing agencies and changing ownerships...

  8. Decentralized manufacturing of cell and gene therapies: Overcoming challenges and identifying opportunities.

    PubMed

    Harrison, Richard P; Ruck, Steven; Medcalf, Nicholas; Rafiq, Qasim A

    2017-10-01

    Decentralized or "redistributed" manufacturing has the potential to revolutionize the manufacturing approach for cell and gene therapies (CGTs), moving away from the "Fordist" paradigm, delivering health care locally, customized to the end user and, by its very nature, overcoming many of the challenges associated with manufacturing and distribution of high volume goods. In departing from the traditional centralized model of manufacturing, decentralized manufacturing divides production across sites or geographic regions. This paradigm shift imposes significant structural and organisational changes on a business presenting both hidden challenges that must be addressed and opportunities to be embraced. By profoundly adapting business practices, significant advantages can be realized through a democratized value chain, creation of professional-level jobs without geographic restriction to the central hub and a flexibility in response to external pressures and demands. To realize these potential opportunities, however, advances in manufacturing technology and support systems are required, as well as significant changes in the way CGTs are regulated to facilitate multi-site manufacturing. Decentralized manufacturing is likely to be the manufacturing platform of choice for advanced health care therapies-in particular, those with a high degree of personalization. The future success of these promising products will be enhanced by adopting sound business strategies early in development. To realize the benefits that decentralized manufacturing of CGTs has to offer, it is important to examine both the risks and the substantial opportunities present. In this research, we examine both the challenges and the opportunities this shift in business strategy represents in an effort to maximize the success of adoption. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Arsenic and Environmental Health: State of the Science and Future Research Opportunities

    PubMed Central

    Carlin, Danielle J.; Naujokas, Marisa F.; Bradham, Karen D.; Cowden, John; Heacock, Michelle; Henry, Heather F.; Lee, Janice S.; Thomas, David J.; Thompson, Claudia; Tokar, Erik J.; Waalkes, Michael P.; Birnbaum, Linda S.; Suk, William A.

    2015-01-01

    Background: Exposure to inorganic and organic arsenic compounds is a major public health problem that affects hundreds of millions of people worldwide. Exposure to arsenic is associated with cancer and noncancer effects in nearly every organ in the body, and evidence is mounting for health effects at lower levels of arsenic exposure than previously thought. Building from a tremendous knowledge base with > 1,000 scientific papers published annually with “arsenic” in the title, the question becomes, what questions would best drive future research directions? Objectives: The objective is to discuss emerging issues in arsenic research and identify data gaps across disciplines. Methods: The National Institutes of Health’s National Institute of Environmental Health Sciences Superfund Research Program convened a workshop to identify emerging issues and research needs to address the multi-faceted challenges related to arsenic and environmental health. This review summarizes information captured during the workshop. Discussion: More information about aggregate exposure to arsenic is needed, including the amount and forms of arsenic found in foods. New strategies for mitigating arsenic exposures and related health effects range from engineered filtering systems to phytogenetics and nutritional interventions. Furthermore, integration of omics data with mechanistic and epidemiological data is a key step toward the goal of linking biomarkers of exposure and susceptibility to disease mechanisms and outcomes. Conclusions: Promising research strategies and technologies for arsenic exposure and adverse health effect mitigation are being pursued, and future research is moving toward deeper collaborations and integration of information across disciplines to address data gaps. Citation: Carlin DJ, Naujokas MF, Bradham KD, Cowden J, Heacock M, Henry HF, Lee JS, Thomas DJ, Thompson C, Tokar EJ, Waalkes MP, Birnbaum LS, Suk WA. 2016. Arsenic and environmental health: state of the

  10. Resident research associateships. Postdoctoral and senior research awards: Opportunities for research at the Jet Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Opportunities for research as part of NASA-sponsored programs at the JPL cover: Earth and space sciences; systems; telecommunications science and engineering; control and energy conversion; applied mechanics; information systems; and observational systems. General information on applying for an award for tenure as a guest investigator, conditions, of the award, and details of the application procedure are provided.

  11. Postsecondary Education Opportunity. The Mortenson Research Seminar on Public Policy Analysis of Opportunity for Postsecondary Education, 1996.

    ERIC Educational Resources Information Center

    Mortenson, Thomas G., Ed.

    1996-01-01

    This document is a collection of 12 issues of a monthly report on public policy and programs affecting postsecondary educational opportunity. Each issue contains two or three research articles analyzing postsecondary educational trends. Titles of articles include: "Students with Educational Disabilities"; "Bureau of Labor Statistics…

  12. Funding opportunities for clinical investigators in the early stages of career development in cardiovascular research.

    PubMed

    Mentz, Robert J; Becker, Richard C

    2013-11-01

    Contemporary cardiovascular research offers junior investigators the opportunity to explore the gamut of biomedical questions. Despite the recent reduction in the availability of funding mechanisms that have historically served as the primary pathways for investigators in the early stages of career development, there remain numerous traditional and non-traditional funding opportunities. This article highlights these opportunities in order to assist early career investigators in the development of a personalized research trajectory, which optimizes the potential for career success.

  13. Identity-Based Motivation: Constraints and Opportunities in Consumer Research

    PubMed Central

    Shavitt, Sharon; Torelli, Carlos J.; Wong, Jimmy

    2009-01-01

    This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, 2009). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities. PMID:20161045

  14. Identity-Based Motivation: Constraints and Opportunities in Consumer Research.

    PubMed

    Shavitt, Sharon; Torelli, Carlos J; Wong, Jimmy

    2009-07-01

    This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, 2009). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities.

  15. Stimulating the clinical academics of tomorrow: a survey of research opportunities for medical students in New Zealand.

    PubMed

    Al-Busaidi, Ibrahim S; Wells, Cameron I

    2017-09-22

    Developing the clinical academic workforce of the future is a priority of international relevance. Despite a number of measures implemented to address this challenge, a small proportion of medical students engage in research. Lack of knowledge of available research opportunities, and difficulty finding projects and suitable mentors are key barriers to undergraduate medical research. To date, there is no consolidated source of information on undergraduate research training opportunities and their outcomes available to medical students in New Zealand. Based on a comprehensive review of the published and grey literature and the authors' personal experiences of research training activities as medical students, this article presents an overview of the research training opportunities available to medical students in New Zealand. Challenges facing medical student research involvement are discussed and current knowledge gaps in the literature are highlighted. The article concludes with suggested strategies to help promote research training opportunities and support students through their research experience.

  16. The value-added laboratory: an opportunity to merge research and service objectives.

    PubMed

    McDonald, J M

    1997-01-01

    The changing health-care environment is creating a new opportunities for laboratory medicine professionals that correspond with the new health services research agendas. Proving cost-effectiveness and conducting outcomes assessment are becoming vital functions of laboratories in this era of managed care. Laboratorians must take advantage of the resulting opportunities to show how they add value and medical relevance to the health-care delivery system.

  17. Challenges and Opportunities To Deliver Research Services to Parliamentarians in the Japanese Diet.

    ERIC Educational Resources Information Center

    Takeda, Michiyo

    This paper outlines the challenges and opportunities for the services of the Japanese National Diet Library (NDL), especially the Research and Legislative Reference Bureau by using a SWOT (Strength, Weaknesses, Opportunities, and Threats) analysis. The introduction lists the major goals of the NDL's reform. The second section discusses the NDL's…

  18. Protocol for a thematic synthesis to identify key themes and messages from a palliative care research network.

    PubMed

    Nicholson, Emma; Murphy, Tara; Larkin, Philip; Normand, Charles; Guerin, Suzanne

    2016-10-21

    Research networks that facilitate collaborative research are increasing both regionally and globally and such collaborations contribute greatly to knowledge transfer particularly in health research. The Palliative Care Research Network is an Irish-based network that seeks to create opportunities and engender a collaborative environment to encourage innovative research that is relevant for policy and practice. The current review outlines a methodology to identify cross-cutting messages to identify how dissemination outputs can be optimized to ensure that key messages from this research reaches all knowledge users. Preferred reporting items for systematic review and meta-analysis protocol guidelines will inform the search and analysis plan to ensure that the synthesis of the data is as rigorous as possible. An approach based on critical interpretative synthesis will be adapted to include a thematic synthesis for the identification of higher-order themes and messages from a body of dissemination products generated by the Palliative Care Research Network. The thematic synthesis outlined in the present protocol offers a novel method of synthesising data from a focused research network that employs a variety of dissemination materials as a means of identifying key themes and messages from a specific body of research. The high-level themes and messages will be identified from the thematic synthesis, widely disseminated and targeted towards a range of stakeholders and knowledge users such as carers, health and social care professionals, policy makers and researchers.

  19. Science and engineering research opportunities at the National Science Foundation.

    PubMed

    Demir, Semahat S

    2004-01-01

    Research at the interface of the physical sciences and life sciences has produced remarkable advances and understanding in biology and medicine over the past fifty years. These bases for many of these healthcare and research advances have been discoveries in the quantitative sciences and engineering approaches to applying them. The National Science Foundation supports research and development in the physical sciences which underpins multi-disciplinary approaches to addressing problems in biology and medicine. This presentation will cover research opportunities offered by the NSF and collaborative programs with the NIH to transfer the resulting advances and technologies.

  20. The Oregon health insurance experiment: when limited policy resources provide research opportunities.

    PubMed

    Allen, Heidi; Baicker, Katherine; Taubman, Sarah; Wright, Bill; Finkelstein, Amy

    2013-12-01

    In 2008 Oregon allocated access to its Medicaid expansion program, Oregon Health Plan Standard, by drawing names from a waiting list by lottery. The lottery was chosen by policy makers and stakeholders as the preferred way to allocate limited resources. At the same time, it also gave rise to the Oregon Health Insurance Experiment: an unprecedented opportunity to do a randomized evaluation - the gold standard in medical and scientific research - of the impact of expanding Medicaid. In this article we provide historical context for Oregon's decision to conduct a lottery, discuss the importance of randomized controlled designs for policy evaluation, and describe some of the practical challenges in successfully capitalizing on the research opportunity presented by the Oregon lottery through public-academic partnerships. Since policy makers will always face tough choices about how to distribute scarce resources, we urge thoughtful consideration of the opportunities to incorporate randomization that can substantially improve the evidence available to inform policy decisions without compromising policy goals.

  1. A Review of NCI’s Extramural Grant Portfolio: Identifying Opportunities for Future Research in Genes and Environment in Cancer

    PubMed Central

    Ghazarian, Armen A.; Simonds, Naoko I.; Bennett, Kelly; Pimentel, Camilla B.; Ellison, Gary L.; Gillanders, Elizabeth M.; Schully, Sheri D.; Mechanic, Leah E.

    2013-01-01

    Background Genetic and environmental factors jointly influence cancer risk. The National Institutes of Health (NIH) has made the study of gene-environment (GxE) interactions a research priority since the year 2000. Methods To assess the current status of GxE research in cancer, we analyzed the extramural grant portfolio of the National Cancer Institute (NCI) from Fiscal Years 2007 to 2009. Publications attributed to selected grants were also evaluated. Results From the 1,106 research grants identified in our portfolio analysis, a random sample of 450 grants (40%) was selected for data abstraction; of these, 147 (33%) were considered relevant. The most common cancer type was breast (20%, n=29), followed by lymphoproliferative (10%, n=14), colorectal (9%, n=13), melanoma/other skin (9%, n=13), and lung/upper aero-digestive tract (8%, n=12) cancers. The majority of grants were studies of candidate genes (68%, n=100) compared to genome-wide association studies (GWAS) (8%, n=12). Approximately one third studied environmental exposures categorized as energy balance (37%, n=54) or drugs/treatment (29%, n=43). From the 147 relevant grants, 108 publications classified as GxE or pharmacogenomic were identified. These publications were linked to 37 of the 147 grant applications (25%). Conclusion The findings from our portfolio analysis suggest that GxE studies are concentrated in specific areas. There is room for investments in other aspects of GxE research, including, but not limited to developing alternative approaches to exposure assessment, broadening the spectrum of cancer types investigated, and performing GxE within GWAS. Impact This portfolio analysis provides a cross-sectional review of NCI support for GxE research in cancer. PMID:23462918

  2. Fostering Sustained Learning among Undergraduate Students: Emerging Research and Opportunities

    ERIC Educational Resources Information Center

    Chemosit, Caroline; Rugutt, John; Rugutt, Joseph K.

    2017-01-01

    Keeping students engaged and receptive to learning can, at times, be a challenge. However, by the implementation of new methods and pedagogies, instructors can strengthen the drive to learn among their students. "Fostering Sustained Learning Among Undergraduate Students: Emerging Research and Opportunities" is an essential publication…

  3. Dissemination, Implementation, and Improvement Science Research in Population Health: Opportunities for Public Health and CTSAs

    PubMed Central

    Gase, Lauren N.; Inkelas, Moira

    2015-01-01

    Abstract Importance The complex, dynamic nature of health systems requires dissemination, implementation, and improvement (DII) sciences to effectively translate emerging knowledge into practice. Although they hold great promise for informing multisector policies and system‐level changes, these methods are often not strategically used by public health. Objectives and Methods More than 120 stakeholders from Southern California, including the community, federal and local government, university, and health services were convened to identify key priorities and opportunities for public health departments and Clinical and Translational Science Awards programs (CTSAs) to advance DII sciences in population health. Main Outcomes Participants identified challenges (mismatch of practice realities with narrowly focused research questions; lack of iterative learning) and solutions (using methods that fit the dynamic nature of the real world; aligning theories of change across sectors) for applying DII science research to public health problems. Pragmatic steps that public health and CTSAs can take to facilitate DII science research include: employing appropriate study designs; training scientists and practicing professionals in these methods; securing resources to advance this work; and supporting team science to solve complex‐systems issues. Conclusions Public health and CTSAs represent a unique model of practice for advancing DII research in population health. The partnership can inform policy and program development in local communities. PMID:26243323

  4. Dissemination, Implementation, and Improvement Science Research in Population Health: Opportunities for Public Health and CTSAs.

    PubMed

    Kuo, Tony; Gase, Lauren N; Inkelas, Moira

    2015-12-01

    The complex, dynamic nature of health systems requires dissemination, implementation, and improvement (DII) sciences to effectively translate emerging knowledge into practice. Although they hold great promise for informing multisector policies and system-level changes, these methods are often not strategically used by public health. More than 120 stakeholders from Southern California, including the community, federal and local government, university, and health services were convened to identify key priorities and opportunities for public health departments and Clinical and Translational Science Awards programs (CTSAs) to advance DII sciences in population health. Participants identified challenges (mismatch of practice realities with narrowly focused research questions; lack of iterative learning) and solutions (using methods that fit the dynamic nature of the real world; aligning theories of change across sectors) for applying DII science research to public health problems. Pragmatic steps that public health and CTSAs can take to facilitate DII science research include: employing appropriate study designs; training scientists and practicing professionals in these methods; securing resources to advance this work; and supporting team science to solve complex-systems issues. Public health and CTSAs represent a unique model of practice for advancing DII research in population health. The partnership can inform policy and program development in local communities. © 2015 Wiley Periodicals, Inc.

  5. Onset Of Opportunity To Use Cannabis And Progression From Opportunity To Dependence: Are Influences Consistent Across Transitions?

    PubMed Central

    Hines, Lindsey A.; Morley, Katherine I.; Strang, John; Agrawal, Arpana; Nelson, Elliot C.; Statham, Dixie; Martin, Nicholas G.; Lynskey, Michael T.

    2016-01-01

    Background There is a developing body of research looking at cannabis use opportunity, but little research examining timing of opportunity to use cannabis. Aims Identify factors associated with 1) earlier opportunity to use cannabis and 2) faster progression from opportunity to cannabis dependence. Method Cross-sectional study of 3824 Australian twins and siblings, measuring age of onset of cannabis use opportunity and DSM-IV cannabis dependence. Survival analysis identified factors associated with faster progression to opportunity or dependence. Results Factors associated with both speed of progression to opportunity and dependence were conduct disorder (opportunity HR 5.57, 95%CI 1.52–20.47; dependence HR 2.49, 95%CI 1.91–3.25), parental drug problems (opportunity HR 7.29, 95%CI 1.74–30.62; dependence HR 3.30, 95%CI 1.63–6.69), weekly tobacco use (opportunity HR 8.57, 95%CI 3.93–18.68; dependence HR 2.76, 95% CI 2.10–3.64), and female gender (opportunity HR 0.69, 95%CI 0.64–0.75; dependence HR 0.44, 95%CI 0.34–0.55). Frequent childhood religious attendance (HR 0.74, 95%CI 0.68–0.80), parental conflict (HR 1.09, 95%CI 1.00–1.18), parental alcohol problems (HR 1.19, 95%CI 1.08–1.30) and childhood sexual abuse (HR 1.17, 95%CI 1.01–1.34) were uniquely associated with transition to opportunity. Depressive episode (HR 1.44, 95%CI 1.12–1.85), tobacco dependence (HR 1.36, 95%CI 1.04 – 1.78), alcohol dependence (HR 2.64, 95%CI 1.53–4.58), other drug use (HR 2.10, 95%CI 1.64–2.69) and other drug dependence (HR 2.75, 95%CI 1.70–4.43) were uniquely associated with progression to dependence. Conclusion The profile of factors associated with opportunity to use cannabis and dependence only partially overlaps, suggesting targeting of interventions may benefit from being tailored to the stages of drug use. PMID:26811121

  6. NIH Researchers Identify OCD Risk Gene

    MedlinePlus

    ... News From NIH NIH Researchers Identify OCD Risk Gene Past Issues / Summer 2006 Table of Contents For ... and Alcoholism (NIAAA) have identified a previously unknown gene variant that doubles an individual's risk for obsessive- ...

  7. Research Opportunities from Emerging Atmospheric Observing and Modeling Capabilities.

    NASA Astrophysics Data System (ADS)

    Dabberdt, Walter F.; Schlatter, Thomas W.

    1996-02-01

    The Second Prospectus Development Team (PDT-2) of the U.S. Weather Research Program was charged with identifying research opportunities that are best matched to emerging operational and experimental measurement and modeling methods. The overarching recommendation of PDT-2 is that inputs for weather forecast models can best be obtained through the use of composite observing systems together with adaptive (or targeted) observing strategies employing both in situ and remote sensing. Optimal observing systems and strategies are best determined through a three-part process: observing system simulation experiments, pilot field measurement programs, and model-assisted data sensitivity experiments. Furthermore, the mesoscale research community needs easy and timely access to the new operational and research datasets in a form that can readily be reformatted into existing software packages for analysis and display. The value of these data is diminished to the extent that they remain inaccessible.The composite observing system of the future must combine synoptic observations, routine mobile observations, and targeted observations, as the current or forecast situation dictates. High costs demand fuller exploitation of commercial aircraft, meteorological and navigation [Global Positioning System (GPS)] satellites, and Doppler radar. Single observing systems must be assessed in the context of a composite system that provides complementary information. Maintenance of the current North American rawinsonde network is critical for progress in both research-oriented and operational weather forecasting.Adaptive sampling strategies are designed to improve large-scale and regional weather prediction but they will also improve diagnosis and prediction of flash flooding, air pollution, forest fire management, and other environmental emergencies. Adaptive measurements can be made by piloted or unpiloted aircraft. Rawinsondes can be launched and satellites can be programmed to make

  8. Qualification and Employment Opportunities. IAB Labour Market Research Topics No. 38.

    ERIC Educational Resources Information Center

    Rauch, Angela; Reinberg, Alexander

    Official German unemployment statistics were analyzed along with data from Germany's microcensus and other published sources to identify recent labor market trends and to clarify the relationship between qualifications and employment opportunities in the new German economy. The analysis revealed that, as has been true for years, the lower the…

  9. Research opportunities with the Centrifuge Facility

    NASA Technical Reports Server (NTRS)

    Funk, Glenn A.

    1992-01-01

    The Centrifuge Facility on Space Station Freedom will consist of a 2.5-meter diameter Centrifuge accommodating two concentric rings of habitats and providing variable g-forces between 0.01 g and 2.0 g; modular habitats providing housing and lifesupport for rats, mice, and plants; a habitat holding system providing power, water, airflow and other utilities to several modular habitats; and a life sciences glovebox, an isolated work volume accommodating simultaneous operations by at least two scientists and providing lighting, airflow, video and data access, and other experiment support functions. The centrifuge facility will enable long-duration animal and plant microgravity research not previously possible in the NASA flight research program. It will offer unprecedented opportunities for use of on-board 1-g control populations and statistically significant numbers of specimens. On orbit 1-g controls will allow separation of the effects of microgravity from other environmental factors. Its selectable-g and simultaneous multiple-g capabilities will enable studies of gravitational thresholds, the use of artificial gravity as a countermeasure to the effects of microgravity, and ready simulation of Lunar and Martian gravities.

  10. Northwest Tribal Interaction with Washington State University: Research and Education Opportunities Afforded Through the Center for Multiphase Environmental Research

    NASA Astrophysics Data System (ADS)

    Rumburg, B.; Yonge, D.; Jacob, J.

    2003-12-01

    The under-representation of Native Americans in engineering and science at the student and practicing engineer or scientist level is a national problem. To begin addressing this problem Washington State University (WSU) has initiated discussio with local Native American tribes to strengthen the relationship between WSU and the tribes and to improve the educational opportunities available to tribal members. The Center for Multiphase Environmental Research (CMER) received a 1999 National Science Foundation (NSF) Integrative Graduate Education and Research Training (IGERT) grant to train Ph.D. students. The main goal of the program is to foster multidisciplinary research and education for future scientists and engineers in the broad field of study that incorporates the fate and transport of environmentally significant species between interfaces. We are also focused on recruiting and educating Native American students. CMER is committed to cultivating its relationship with Native American tribes by identifying the environmental concerns of the tribes and developing collaborative research efforts utilizing CMER's infrastructure. Through these collaborative projects the CMER hopes to better understand the social and cultural aspects important to the tribes and develop the familiarity needed to effectively enhance student recruitment. This poster highlights the CMER's interdisciplinary research and teaching efforts and focuses on Native American recruitment.

  11. Opportunities and challenges in the use of personal health data for health research

    PubMed Central

    Bietz, Matthew J; Bloss, Cinnamon S; Calvert, Scout; Godino, Job G; Gregory, Judith; Claffey, Michael P; Sheehan, Jerry

    2016-01-01

    Objective: Understand barriers to the use of personal health data (PHD) in research from the perspective of three stakeholder groups: early adopter individuals who track data about their health, researchers who may use PHD as part of their research, and companies that market self-tracking devices, apps or services, and aggregate and manage the data that are generated. Materials and Methods: A targeted convenience sample of 465 individuals and 134 researchers completed an extensive online survey. Thirty-five hour-long semi-structured qualitative interviews were conducted with a subset of 11 individuals and 9 researchers, as well as 15 company/key informants. Results: Challenges to the use of PHD for research were identified in six areas: data ownership; data access for research; privacy; informed consent and ethics; research methods and data quality; and the unpredictable nature of the rapidly evolving ecosystem of devices, apps, and other services that leave “digital footprints.” Individuals reported willingness to anonymously share PHD if it would be used to advance research for the good of the public. Researchers were enthusiastic about using PHD for research, but noted barriers related to intellectual property, licensing, and the need for legal agreements with companies. Companies were interested in research but stressed that their first priority was maintaining customer relationships. Conclusion: Although challenges exist in leveraging PHD for research, there are many opportunities for stakeholder engagement, and experimentation with these data is already taking place. These early examples foreshadow a much larger set of activities with the potential to positively transform how health research is conducted. PMID:26335984

  12. Meta-synthesis of qualitative research: the challenges and opportunities.

    PubMed

    Mohammed, Mohammed A; Moles, Rebekah J; Chen, Timothy F

    2016-06-01

    Synthesis of qualitative studies is an emerging area that has been gaining more interest as an important source of evidence for improving health care policy and practice. In the last decade there have been numerous attempts to develop methods of aggregating and synthesizing qualitative data. Although numerous empirical qualitative studies have been published about different aspects of health care research, to date, the aggregation and syntheses of these data has not been commonly reported, particularly in pharmacy practice related research. This paper describes different methods of conducting meta-synthesis and provides an overview of selected common methods. The paper also emphasizes the challenges and opportunities associated with conducting meta-synthesis and highlights the importance of meta-synthesis in informing practice, policy and research.

  13. TH-AB-BRB-00: Research Opportunities with Digital Linear Accelerators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2016-06-15

    Current state-of-the art digital C-arm medical linear accelerators are capable of delivering radiation treatments with high level of automation, which affords coordinated motions of gantry, couch, and multileaf collimator (MLC) with dose rate modulations. The new machine capacity has shown the potential to bring substantially improved radiation dosimetry and/or delivery efficiency to many challenging diseases. Combining an integrated beam orientation optimization algorithm with automated machine navigation, markedly improved dose conformity has been achieved using 4ρ therapy. Trajectory modulated radiation therapy (TMAT) can be used to deliver highly conformal dose to partial breast or to carve complex dose distribution for therapymore » involving extended volumes such as total marrow and total lymph node treatment. Dynamic electron arc radiotherapy (DEAR) not only overcomes the deficiencies of conventional electron therapy in dose conformity and homogeneity but also achieves so without patient-specific shields. The combination of MLC and couch tracking provides improved motion management of thoracic and abdominal tumors. A substantial body of work has been done in these technological advances for clinical translation. The proposed symposium will provide a timely review of these exciting opportunities. Learning Objectives: Recognize the potential of using digitally controlled linacs for clinically significant improvements in delivered dose distributions for various treatment sites. Identify existing approaches to treatment planning, optimization and delivery for treatment techniques utilizing the advanced functions of digital linacs and venues for further development and improvement. Understand methods for testing and validating delivery system performance. Identify tools available on current delivery systems for implementation and control for such treatments. Obtain the update in clinical applications, trials and regulatory approval. K. Sheng, NIH U19AI067769

  14. Fundamental Science with Pulsed Power: Research Opportunities and User Meeting.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mattsson, Thomas Kjell Rene; Wootton, Alan James; Sinars, Daniel Brian

    The fifth Fundamental Science with Pulsed Power: Research Opportunities and User Meeting was held in Albuquerque, NM, July 20-­23, 2014. The purpose of the workshop was to bring together leading scientists in four research areas with active fundamental science research at Sandia’s Z facility: Magnetized Liner Inertial Fusion (MagLIF), Planetary Science, Astrophysics, and Material Science. The workshop was focused on discussing opportunities for high-­impact research using Sandia’s Z machine, a future 100 GPa class facility, and possible topics for growing the academic (off-Z-campus) science relevant to the Z Fundamental Science Program (ZFSP) and related projects in astrophysics, planetary science, MagLIF-more » relevant magnetized HED science, and materials science. The user meeting was for Z collaborative users to: a) hear about the Z accelerator facility status and plans, b) present the status of their research, and c) be provided with a venue to meet and work as groups. Following presentations by Mark Herrmann and Joel Lash on the fundamental science program on Z and the status of the Z facility where plenary sessions for the four research areas. The third day of the workshop was devoted to breakout sessions in the four research areas. The plenary-­ and breakout sessions were for the four areas organized by Dan Sinars (MagLIF), Dylan Spaulding (Planetary Science), Don Winget and Jim Bailey (Astrophysics), and Thomas Mattsson (Material Science). Concluding the workshop were an outbrief session where the leads presented a summary of the discussions in each working group to the full workshop. A summary of discussions and conclusions from each of the research areas follows and the outbrief slides are included as appendices.« less

  15. Emerging research in micro and nano systems: opportunities and challenges for societal impact

    NASA Astrophysics Data System (ADS)

    Gianchandani, Yogesh B.

    2010-02-01

    In just a few decades, micro and nano technologies have changed the way that we live - how we work and communicate; the food and medicine that we consume; the clothing that we use; and the entertainment that we seek. While these technologies are being actively investigated in several research communities, the potential for continued societal impact is constrained by resources available for system-level research. Given the long time-lines and levels of investment that are typically necessary to develop functional systems, strategic prioritization of research directions from the perspective of societal needs can be helpful. This paper outlines the findings of an NSF-sponsored road-mapping workshop that was held in 2009, with the intention of initiating a conversation about the opportunities and challenges for micro and nano systems. Four areas of need were discussed: environmental sensing; health care; infrastructure monitoring; and energy alternatives. Possible research trajectories were identified by envisioning technological goals for the year 2040, and linking these to horizons for 2015 and 2025. This paper also provides few examples of current research in each of the four application domains. It is noted that a systems perspective can help to keep the research focused, accelerating and amplifying the societal gain with available resources. Practical and affordable solutions at the system level will require partnerships between specialists, and also between academia and industry.

  16. Patient and Family Advisory Councils (PFACs): Identifying Challenges and Solutions to Support Engagement in Research.

    PubMed

    Harrison, James D; Anderson, Wendy G; Fagan, Maureen; Robinson, Edmondo; Schnipper, Jeffrey; Symczak, Gina; Hanson, Catherine; Carnie, Martha B; Banta, Jim; Chen, Sherry; Duong, Jonathan; Wong, Celene; Auerbach, Andrew D

    2018-02-01

    The aim was to describe barriers to patient and family advisory council (PFAC) member engagement in research and strategies to support engagement in this context. We formed a study team comprising patient advisors, researchers, physicians, and nurses. We then undertook a qualitative study using focus groups and interviews. We invited PFAC members, PFAC leaders, hospital leaders, and researchers from nine academic medical centers that are part of a hospital medicine research network to participate. All participants were asked a standard set of questions exploring the study question. We used content analysis to analyze data. Eighty PFAC members and other stakeholders (45 patient/caregiver members of PFACs, 12 PFAC leaders, 12 hospital leaders, 11 researchers) participated in eight focus and 19 individual interviews. We identified ten barriers to PFAC member engagement in research. Codes were organized into three categories: (1) individual PFAC member reluctance; (2) lack of skills and training; and (3) problems connecting with the right person at the right time. We identified ten strategies to support engagement. These were organized into four categories: (1) creating an environment where the PFAC members are making a genuine and unique contribution; (2) building community between PFAC members and researchers; (3) best practice activities for researchers to facilitate engagement; and (4) tools and training. Barriers to engaging PFAC members in research include patients' negative perceptions of research and researchers' lack of training. Building community between PFAC members and researchers is a foundation for partnerships. There are shared training opportunities for PFAC members and researchers to build skills about research and research engagement.

  17. Offering African Americans opportunities to participate in clinical trials research: how social workers can help.

    PubMed

    Mason, Susan E

    2005-11-01

    Historically, African Americans have resisted participation in clinical trials and other research projects because of distrust of the mostly white research establishment. Although there are legitimate reasons for refusing to join clinical trials, most notably the abuses of the Tuskegee Syphilis Study, African Americans may be passing up opportunities to obtain needed medications years before they reach the market. This article analyzes 29 empirical articles from medical and mental health journals for their findings on recruiting and maintaining African Americans in clinical trials. Reasons for declining and accepting opportunities to participate are organized into themes that represent the salient findings of these reports. Suggestions for social work interventions and changes in research designs are intended to make the research process more welcoming to African Americans. Interventions are linked to the themes and incorporate social work ethics and values. The premise of this study is that African Americans should be offered realistic opportunities supported by sufficient resources to increase participation.

  18. Avian research on Experimental Forests and Ranges: Emergent themes, opportunities, and challenges

    Treesearch

    Scott H. Stoleson; David I. King; Monica. Tomosy

    2011-01-01

    Since 1908, U.S. Forest Service Experimental Forests and Ranges have been dedicated to long-term inter-disciplinary research on a variety of ecological and management questions. They encompass a wide diversity of life zones and ecoregions, and provide access to research infrastructure, opportunities for controlled manipulations, and integration with other types of long...

  19. GUIDE TO OPPORTUNITIES FOR EDUCATION, TRAINING AND RESEARCH IN THE SCIENCES.

    ERIC Educational Resources Information Center

    FIELD, STANLEY

    THIS GUIDE TO EDUCATIONAL OPPORTUNITIES IN THE SCIENCES IS INTENDED TO PROVIDE A COMPREHENSIVE AND CONVENIENT REFERENCE FOR GUIDANCE COUNSELORS, STUDENTS, SCHOLARS, RESEARCHERS, EDUCATORS, AND ADMINISTRATORS, BRINGING TOGETHER WIDELY SCATTERED INFORMATION THAT HITHERTO HAS BEEN DIFFICULT TO OBTAIN. CHAPTER 1 DEALS EXCLUSIVELY WITH NATIONAL SCIENCE…

  20. [From record keeping to scientific research: obstacles and opportunities for research with electronic health records].

    PubMed

    Scholte, R A; Opmeer, B C; Ploem, M C

    2017-01-01

    As a result of increasing digitisation of medical record keeping, electronic health records (EHRs) are an attractive source for data reuse. However, such record-based research is still suffering from poor quality of data stored in EHRs. Lack of consent for reuse of data also plays an impeding role, especially in retrospective record-based research. That said, increasing cooperation between healthcare institutions and current attention for EHR organisation also offer opportunities for record-based research. Patient data can be recorded in more standardised ways and in increasingly harmonised EHRs. In addition, if healthcare institutions were to establish a generic consent procedure - preferably with national scope - the potential of EHRs for scientific research could be exploited in considerably better ways.

  1. Sustainability in Health care by Allocating Resources Effectively (SHARE) 2: identifying opportunities for disinvestment in a local healthcare setting.

    PubMed

    Harris, Claire; Allen, Kelly; King, Richard; Ramsey, Wayne; Kelly, Cate; Thiagarajan, Malar

    2017-05-05

    This is the second in a series of papers reporting a program of Sustainability in Health care by Allocating Resources Effectively (SHARE) in a local healthcare setting. Rising healthcare costs, continuing advances in health technologies and recognition of ineffective practices and systematic waste are driving disinvestment of health technologies and clinical practices that offer little or no benefit in order to maximise outcomes from existing resources. However there is little information to guide regional health services or individual facilities in how they might approach disinvestment locally. This paper outlines the investigation of potential settings and methods for decision-making about disinvestment in the context of an Australian health service. Methods include a literature review on the concepts and terminology relating to disinvestment, a survey of national and international researchers, and interviews and workshops with local informants. A conceptual framework was drafted and refined with stakeholder feedback. There is a lack of common terminology regarding definitions and concepts related to disinvestment and no guidance for an organisation-wide systematic approach to disinvestment in a local healthcare service. A summary of issues from the literature and respondents highlight the lack of theoretical knowledge and practical experience and provide a guide to the information required to develop future models or methods for disinvestment in the local context. A conceptual framework was developed. Three mechanisms that provide opportunities to introduce disinvestment decisions into health service systems and processes were identified. Presented in order of complexity, time to achieve outcomes and resources required they include 1) Explicit consideration of potential disinvestment in routine decision-making, 2) Proactive decision-making about disinvestment driven by available evidence from published research and local data, and 3) Specific exercises in

  2. Group-effort applied research: expanding opportunities for undergraduate research through original, class-based research projects.

    PubMed

    Moore, Sean D; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's laboratory. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student-one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this article, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. © 2014 The International Union of Biochemistry and Molecular Biology.

  3. Observational Research Opportunities and Limitations

    PubMed Central

    Boyko, Edward J.

    2013-01-01

    Medical research continues to progress in its ability to identify treatments and characteristics associated with benefits and adverse outcomes. The principle engine for the evaluation of treatment efficacy is the randomized controlled trial (RCT). Due to the cost and other considerations, RCTs cannot address all clinically important decisions. Observational research often is used to address issues not addressed or not addressable by RCTs. This article provides an overview of the benefits and limitations of observational research to serve as a guide to the interpretation of this category of research designs in diabetes investigations. The potential for bias is higher in observational research but there are design and analysis features that can address these concerns although not completely eliminate them. Pharmacoepidemiologic research may provide important information regarding relative safety and effectiveness of diabetes pharmaceuticals. Such research must effectively address the important issue of confounding by indication in order to produce clinically meaningful results. Other methods such as instrumental variable analysis are being employed to enable stronger causal inference but these methods also require fulfillment of several key assumptions that may or may not be realistic. Nearly all clinical decisions involve probabilistic reasoning and confronting uncertainly, so a realistic goal for observational research may not be the high standard set by RCTs but instead the level of certainty needed to influence a diagnostic or treatment decision. PMID:24055326

  4. Observational research--opportunities and limitations.

    PubMed

    Boyko, Edward J

    2013-01-01

    Medical research continues to progress in its ability to identify treatments and characteristics associated with benefits and adverse outcomes. The principal engine for the evaluation of treatment efficacy is the randomized controlled trial (RCT). Due to the cost and other considerations, RCTs cannot address all clinically important decisions. Observational research often is used to address issues not addressed or not addressable by RCTs. This article provides an overview of the benefits and limitations of observational research to serve as a guide to the interpretation of this category of research designs in diabetes investigations. The potential for bias is higher in observational research but there are design and analysis features that can address these concerns although not completely eliminate them. Pharmacoepidemiologic research may provide important information regarding relative safety and effectiveness of diabetes pharmaceuticals. Such research must effectively address the important issue of confounding by indication in order to produce clinically meaningful results. Other methods such as instrumental variable analysis are being employed to enable stronger causal inference but these methods also require fulfillment of several key assumptions that may or may not be realistic. Nearly all clinical decisions involve probabilistic reasoning and confronting uncertainly, so a realistic goal for observational research may not be the high standard set by RCTs but instead the level of certainty needed to influence a diagnostic or treatment decision. © 2013.

  5. Global Perspectives on Children's Digital Opportunities: An Emerging Research and Policy Agenda.

    PubMed

    Livingstone, Sonia; Lemish, Dafna; Lim, Sun Sun; Bulger, Monica; Cabello, Patricio; Claro, Magdalena; Cabello-Hutt, Tania; Khalil, Joe; Kumpulainen, Kristiina; Nayar, Usha S; Nayar, Priya; Park, Jonghwi; Tan, Maria Melizza; Prinsloo, Jeanne; Wei, Bu

    2017-11-01

    Diverse international perspectives show that children can benefit greatly from digital opportunities. Despite widespread optimism about the potential of digital technologies, especially for information and education, the research reveals an insufficient evidence base to guide policy and practice across all continents of the world, especially in middle- and low-income countries. Beyond revealing pressing and sizeable gaps in knowledge, this cross-national review also reveals the importance of understanding local values and practices regarding the use of technologies. This leads us to stress that future researchers must take into account local contexts and existing inequalities and must share best practices internationally so that children can navigate the balance between risks and opportunities. This article documents the particular irony that while the world's poorer countries look to research to find ways to increase access and accelerate the fair distribution of digital educational resources, the world's wealthier countries look to research for guidance in managing excessive screen time, heavily commercial content, and technologies that intrude on autonomy and privacy. We conclude by recommending that digital divides should be carefully bridged with contextual sensitivity to avoid exacerbating existing disparities; that the provision of technological resources is complemented by a focus on skills enhancement, for teachers as well as students; that a keen eye is needed to ensure the balance of children's protection and participation rights, with protection now including data abuses as well as safety considerations; and that we forge collaborations among all stakeholders in seeking to enhance children's digital opportunities worldwide. Copyright © 2017 by the American Academy of Pediatrics.

  6. Extracurricular participation in research and audit by medical students: opportunities, obstacles, motivation and outcomes.

    PubMed

    Nikkar-Esfahani, Ali; Jamjoom, Aimun A B; Fitzgerald, J Edward F

    2012-01-01

    Medical students should learn to critically evaluate research to inform future evidence-based practice. Participation in research and audit at medical school can help develop these skills whilst prompting interest in academic pursuits. We investigate medical student attitudes and participation in extracurricular research and audit focusing on their opportunities, obstacles, motivation and outcomes. A 60-item questionnaire was distributed to final-year medical students graduating from the University of Nottingham Medical School in the United Kingdom. A total of 238 questionnaires were returned (response rate 75%). Of these, 86% felt research or audit experience was useful for medical students. The main driver for involvement was curriculum vitae (CV) improvement (51%). Male students and those involved in extracurricular research were more likely to agree that this experience should influence selection into training programmes (p = 0.017, p = 0.0036). Overall, 91 respondents (38%) had been involved in such activity with a mean number of projects undertaken of two (range one to four). Those interested in a surgical career were most likely to have undertaken projects (58%). Frequently cited obstacles to involvement were time constraints (74%) and a perceived lack of interest from potential supervisors (63%). Despite significant CV motivation, many are enthusiastic regarding extracurricular research opportunities but frustrated by obstacles faced. Our study suggests there is scope for providing further opportunities to participate in such activities at medical school.

  7. Diagnosing climate change impacts and identifying adaptation strategies by involving key stakeholder organisations and farmers in Sikkim, India: Challenges and opportunities.

    PubMed

    Azhoni, Adani; Goyal, Manish Kumar

    2018-06-01

    Narrowing the gap between research, policy making and implementing adaptation remains a challenge in many parts of the world where climate change is likely to severely impact water security. This research aims to narrow this gap by matching the adaptation strategies being framed by policy makers to that of the perspectives of development agencies, researchers and farmers in the Himalayan state of Sikkim in India. Our case study examined the perspectives of various stakeholders for climate change impacts, current adaptation strategies, knowledge gaps and adaptation barriers, particularly in the context of implementing the Sikkim State Action Plan on Climate Change through semi-structured interviews carried out with decision makers in the Sikkim State Government, researchers, consultants, local academia, development agencies and farmers. Using Stakeholders Network Analysis tools, this research unravels the complexities of perceiving climate change impacts, identifying strategies, and implementing adaptation. While farmers are less aware about the global phenomenon of climate change impacts for water security, their knowledge of the local conditions and their close interaction with the State Government Agriculture Department provides them opportunities. Although important steps are being initiated through the Sikkim State Action Plan on Climate Change it is yet to deliver effective means of adaptation implementation and hence, strengthening the networks of close coordination between the various implementing agencies will pay dividends. Knowledge gaps and the need for capacity building identified in this research, based on the understandings of key stakeholders are highly relevant to both the research community and for informing policy. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Opportunities and challenges in the use of personal health data for health research.

    PubMed

    Bietz, Matthew J; Bloss, Cinnamon S; Calvert, Scout; Godino, Job G; Gregory, Judith; Claffey, Michael P; Sheehan, Jerry; Patrick, Kevin

    2016-04-01

    Understand barriers to the use of personal health data (PHD) in research from the perspective of three stakeholder groups: early adopter individuals who track data about their health, researchers who may use PHD as part of their research, and companies that market self-tracking devices, apps or services, and aggregate and manage the data that are generated. A targeted convenience sample of 465 individuals and 134 researchers completed an extensive online survey. Thirty-five hour-long semi-structured qualitative interviews were conducted with a subset of 11 individuals and 9 researchers, as well as 15 company/key informants. Challenges to the use of PHD for research were identified in six areas: data ownership; data access for research; privacy; informed consent and ethics; research methods and data quality; and the unpredictable nature of the rapidly evolving ecosystem of devices, apps, and other services that leave "digital footprints." Individuals reported willingness to anonymously share PHD if it would be used to advance research for the good of the public. Researchers were enthusiastic about using PHD for research, but noted barriers related to intellectual property, licensing, and the need for legal agreements with companies. Companies were interested in research but stressed that their first priority was maintaining customer relationships. Although challenges exist in leveraging PHD for research, there are many opportunities for stakeholder engagement, and experimentation with these data is already taking place. These early examples foreshadow a much larger set of activities with the potential to positively transform how health research is conducted. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. How to Locate Business Opportunities at the Office of Naval Research

    DTIC Science & Technology

    2012-08-01

    Click to edit Master title style How  to  Locate  Business  Opportuni2es  at   the   Office  of  Naval  Research     Navy...4. TITLE AND SUBTITLE How to Locate Business Opportunities at the Office of Naval Research 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...Prescribed by ANSI Std Z39-18 The Office of Naval Research’s (ONR) mission – defined by law – “…is to plan, foster and encourage scientific research

  10. Forest Service Career Guide. Professional Opportunities in Natural Resource Management, Planning, and Research. Revised Edition.

    ERIC Educational Resources Information Center

    Forest Service (USDA), Washington, DC.

    The guide provides information on professional opportunities in natural resource management, planning, and research. Reasons for careers in forest service are presented and a brief description of the forest service is provided. Career opportunities in the following areas are described: forestry, engineering, geology, hydrology, landscape…

  11. Identifying Eating Occasion-Based Opportunities to Improve the Overall Diets of Australian Adolescents

    PubMed Central

    Fayet-Moore, Flavia; McConnell, Andrew; Kim, Jean; Mathias, Kevin C.

    2017-01-01

    Adolescents in Australia have a poor dietary intake, leading to large numbers of them being at risk for inadequate intake of micronutrients, and excessive intake of less healthful dietary components. This study examined dietary intakes at multiple eating occasions to identify opportunities for more targeted recommendations and strategies to improve dietary intakes among adolescents. Data from the first 24-h recall of 14–18 years old in the 2011–2012 National Nutrition and Physical Activity Survey were analysed (n = 772). Participant-defined eating occasions were classified as breakfast, lunch, dinner or other eating occasions combined. The mean percent contribution to the total day intake of top shortfall nutrients (calcium, magnesium, vitamin A, iron), discretionary calories, saturated fat, free sugars and sodium, as well as nutrient density, the foods consumed and the percent of consumers at each eating occasion, were calculated. Breakfast had the lowest prevalence of consumers (81%), contributed the least to total daily energy (14.6%) and almost a quarter of daily calcium and iron. Other eating occasions combined contributed 47.5% of free sugars and were top contributors of daily calcium (34.6%) and magnesium (31.7%). Discretionary foods contributed 32.4% of the energy at lunch, and the sodium content at lunch was 415 mg/1000 kJ. Key opportunities identified for adolescents were to increase breakfast consumption, given the high nutrient densities of breakfasts consumed; improve overall lunch quality, particularly the sodium content; promote the intake of milk, fruit and a variety of vegetables at both lunch and dinner; maintain healthful choices at in-between meal eating occasions while focusing on decreasing the intake of discretionary foods. PMID:28613261

  12. Group-Effort Applied Research (GEAR): Expanding Opportunities for Undergraduate Research Through Original, Class-Based Research Projects

    PubMed Central

    Moore, Sean D.; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student - one mentor model for undergraduate research. Group-Effort Applied Research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's lab. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student - one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this paper, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. PMID:24898007

  13. Challenges and Opportunities for Harmonizing Research Methodology: Raw Accelerometry.

    PubMed

    van Hees, Vincent T; Thaler-Kall, Kathrin; Wolf, Klaus-Hendrik; Brønd, Jan C; Bonomi, Alberto; Schulze, Mareike; Vigl, Matthäus; Morseth, Bente; Hopstock, Laila Arnesdatter; Gorzelniak, Lukas; Schulz, Holger; Brage, Søren; Horsch, Alexander

    2016-12-07

    Raw accelerometry is increasingly being used in physical activity research, but diversity in sensor design, attachment and signal processing challenges the comparability of research results. Therefore, efforts are needed to harmonize the methodology. In this article we reflect on how increased methodological harmonization may be achieved. The authors of this work convened for a two-day workshop (March 2014) themed on methodological harmonization of raw accelerometry. The discussions at the workshop were used as a basis for this review. Key stakeholders were identified as manufacturers, method developers, method users (application), publishers, and funders. To facilitate methodological harmonization in raw accelerometry the following action points were proposed: i) Manufacturers are encouraged to provide a detailed specification of their sensors, ii) Each fundamental step of algorithms for processing raw accelerometer data should be documented, and ideally also motivated, to facilitate interpretation and discussion, iii) Algorithm developers and method users should be open about uncertainties in the description of data and the uncertainty of the inference itself, iv) All new algorithms which are pitched as "ready for implementation" should be shared with the community to facilitate replication and ongoing evaluation by independent groups, and v) A dynamic interaction between method stakeholders should be encouraged to facilitate a well-informed harmonization process. The workshop led to the identification of a number of opportunities for harmonizing methodological practice. The discussion as well as the practical checklists proposed in this review should provide guidance for stakeholders on how to contribute to increased harmonization.

  14. Inclusive Branding Strategies for Domestic Violence Agencies: Embracing Opportunities to Reach and Better Serve Male-Identified Survivors.

    PubMed

    Dewey, Morgan; Heiss, Sarah N

    2018-05-01

    Successful strategies for branding that are inclusive of male-identified survivors were identified in this qualitative study through semi-structured interviews with leaders from six domestic violence agencies across the United States: four represented traditional domestic violence agencies and two represented specialized agencies with expertise in providing services to nontraditional survivors. The strategic implementation of (a) inclusive language, (b) visual diversity, (c) community outreach, and (d) communication channels emerged as successful strategies in branding in an inclusive way for male-identified survivors. The implementation of these successful strategies provides the opportunity for domestic violence agencies to create an inclusive environment for male-identified survivors and would contribute to a paradigm shift in how domestic violence is viewed.

  15. Market opportunities for kitchen cabinets made from Alaska hardwoods: a synthesis and review of recent research.

    Treesearch

    David L. Nicholls; Maria C. Stiefel

    2007-01-01

    The kitchen cabinet industry has shown significant growth recently, with expanding residential markets, new cabinet styles, and larger kitchens. This industry represents an opportunity for small Alaska wood producers to create high-value secondary products. In response to recent trends in kitchen cabinet manufacturing and the need to identify opportunities for...

  16. Community health workers and the Patient Protection and Affordable Care Act: an opportunity for a research, advocacy, and policy agenda.

    PubMed

    Shah, Megha K; Heisler, Michele; Davis, Matthew M

    2014-02-01

    Community health workers (CHWs), who have been shown to be effective in multiple roles in the provision of culturally appropriate health care in a variety of settings, have the potential to be important members of an interdisciplinary health care team. Recent efforts have started to explore how best to integrate CHWs into the health system. However, to date, there has been limited policy guidance, support, or evidence on how best to achieve this on a larger scale. The Patient Protection and Affordable Care Act (ACA), through several provisions, provides a unique opportunity to create a unified framework for workforce integration and wider utilization of CHWs. This review identifies four major opportunities to further the research, advocacy, and policy agenda for CHWs.

  17. A PREFERENCE-OPPORTUNITY-CHOICE FRAMEWORK WITH APPLICATIONS TO INTERGROUP FRIENDSHIP*

    PubMed Central

    Zeng, Zhen; Xie, Yu

    2009-01-01

    A longstanding objective of friendship research is to identify the effects of personal preference and structural opportunity on intergroup friendship choice. Although past studies have used various methods to separate preference from opportunity, researchers have not yet systematically compared the properties and implications of these methods. We put forward a general framework for discrete choice, where choice probability is specified as proportional to the product of preference and opportunity. To implement this framework, we propose a modification to the conditional logit model for estimating preference parameters free from the influence of opportunity structure. We then compare our approach to several alternative methods for separating preference and opportunity used in the friendship choice literature. As an empirical example, we test hypotheses of homophily and status asymmetry in friendship choice using data from the National Longitudinal Study of Adolescent Health. The example also demonstrates the approach of conducting a sensitivity analysis to examine how parameter estimates vary by specification of the opportunity structure. PMID:19569394

  18. Multicenter collaborative for orthopaedic research in India: An opportunity for global leadership

    PubMed Central

    Mathew, George; Sancheti, Parag; Jain, Anil; Bhandari, Mohit

    2008-01-01

    Road traffic accidents are increasing at an alarming rate and have become a major public health concern in India. In addition, there is a lack of trauma research output and reliable data from India. There are several issues and challenges that have presented an opportunity for researchers and surgeons in India to develop a collaborative aimed at improving the quality and productivity of orthopaedic trauma research. Establishing a network of surgical researchers across India is a necessary first step towards global leadership in orthopaedic surgery trials. PMID:19826521

  19. Optimising Translational Research Opportunities: A Systematic Review and Narrative Synthesis of Basic and Clinician Scientists' Perspectives of Factors Which Enable or Hinder Translational Research

    PubMed Central

    Sadler, Euan; Fisher, Helen R.; Maher, John; Wolfe, Charles D. A.; McKevitt, Christopher

    2016-01-01

    Introduction Translational research is central to international health policy, research and funding initiatives. Despite increasing use of the term, the translation of basic science discoveries into clinical practice is not straightforward. This systematic search and narrative synthesis aimed to examine factors enabling or hindering translational research from the perspective of basic and clinician scientists, a key stakeholder group in translational research, and to draw policy-relevant implications for organisations seeking to optimise translational research opportunities. Methods and Results We searched SCOPUS and Web of Science from inception until April 2015 for papers reporting scientists’ views of the factors they perceive as enabling or hindering the conduct of translational research. We screened 8,295 papers from electronic database searches and 20 papers from hand searches and citation tracking, identifying 26 studies of qualitative, quantitative or mixed method designs. We used a narrative synthesis approach and identified the following themes: 1) differing concepts of translational research 2) research processes as a barrier to translational research; 3) perceived cultural divide between research and clinical care; 4) interdisciplinary collaboration as enabling translation research, but dependent on the quality of prior and current social relationships; 5) translational research as entrepreneurial science. Across all five themes, factors enabling or hindering translational research were largely shaped by wider social, organisational, and structural factors. Conclusion To optimise translational research, policy could consider refining translational research models to better reflect scientists’ experiences, fostering greater collaboration and buy in from all types of scientists. Organisations could foster cultural change, ensuring that organisational practices and systems keep pace with the change in knowledge production brought about by the

  20. Optimising Translational Research Opportunities: A Systematic Review and Narrative Synthesis of Basic and Clinician Scientists' Perspectives of Factors Which Enable or Hinder Translational Research.

    PubMed

    Fudge, Nina; Sadler, Euan; Fisher, Helen R; Maher, John; Wolfe, Charles D A; McKevitt, Christopher

    2016-01-01

    Translational research is central to international health policy, research and funding initiatives. Despite increasing use of the term, the translation of basic science discoveries into clinical practice is not straightforward. This systematic search and narrative synthesis aimed to examine factors enabling or hindering translational research from the perspective of basic and clinician scientists, a key stakeholder group in translational research, and to draw policy-relevant implications for organisations seeking to optimise translational research opportunities. We searched SCOPUS and Web of Science from inception until April 2015 for papers reporting scientists' views of the factors they perceive as enabling or hindering the conduct of translational research. We screened 8,295 papers from electronic database searches and 20 papers from hand searches and citation tracking, identifying 26 studies of qualitative, quantitative or mixed method designs. We used a narrative synthesis approach and identified the following themes: 1) differing concepts of translational research 2) research processes as a barrier to translational research; 3) perceived cultural divide between research and clinical care; 4) interdisciplinary collaboration as enabling translation research, but dependent on the quality of prior and current social relationships; 5) translational research as entrepreneurial science. Across all five themes, factors enabling or hindering translational research were largely shaped by wider social, organisational, and structural factors. To optimise translational research, policy could consider refining translational research models to better reflect scientists' experiences, fostering greater collaboration and buy in from all types of scientists. Organisations could foster cultural change, ensuring that organisational practices and systems keep pace with the change in knowledge production brought about by the translational research agenda.

  1. Challenges and Opportunities for Exploring Patient-Level Data

    PubMed Central

    Lopes, Pedro; Silva, Luis Bastião; Oliveira, José Luis

    2015-01-01

    The proper exploration of patient-level data will pave the way towards personalised medicine. To better assess the state of the art in this field we identify the challenges and uncover the opportunities for the exploration of patient-level data through the review of well-known initiatives and projects focusing on the exploration of patient-level data. These cover a broad array of topics, from genomics to patient registries up to rare diseases research, among others. For each, we identified basic goals, involved partners, defined strategies and key technological and scientific outcomes, establishing the foundation for our analysis framework with four pillars: control, sustainability, technology, and science. Substantial research outcomes have been produced towards the exploration of patient-level data. The potential behind these data will be essential to realise the personalised medicine premise in upcoming years. Hence, relevant stakeholders continually push forward new developments in this domain, bringing novel opportunities that are ripe for exploration. Despite last decade's translational research advances, personalised medicine is still far from being a reality. Patients' data underlying potential goes beyond daily clinical practice. There are miscellaneous challenges and opportunities open for the exploration of these data by academia and business stakeholders. PMID:26504779

  2. Unique educational opportunities at the Missouri University research reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ketring, A.R.; Ross, F.K.; Spate, V.

    1997-12-01

    Since the Missouri University Research Reactor (MURR) went critical in 1966, it has been a center where students from many departments conduct their graduate research. In the past three decades, hundreds of graduate students from the MU departments of chemistry, physics, anthropology, nuclear engineering, etc., have received masters and doctoral degrees based on research using neutrons produced at MURR. More recently, the educational opportunities at MURR have been expanded to include undergraduate students and local high school students. Since 1989 MURR has participated in the National Science Foundation-funded Research Experience for Undergraduates (REU) program. As part of this program, undergraduatemore » students from universities and colleges throughout the United States come to MURR and get hands-on research experience during the summer. Another program, started in 1994 by the Nuclear Analysis Program at MURR, allows students from a local high school to conduct a neutron activation analysis (NAA) experiment. We also conduct tours of the center, where we describe the research and educational programs at MURR to groups of elementary school children, high school science teachers, state legislators, professional organizations, and many other groups.« less

  3. Small Business Innovation Research, Post-Phase II Opportunity Assessment

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung D.; Steele, Gynelle C.

    2015-01-01

    This report outlines current Small Business Innovation Research (SBIR) Post-Phase II opportunity contract award results for the SBIR technology program from 2007 to 2011 for NASA's Aeronautics Research Mission Directorate (ARMD), Human Exploration and Operations Mission Directorate (HEOMD), Science Mission Directorate (SMD), and Space Technology Mission Directorate (STMD). The report provides guidelines for incorporating SBIR technology into NASA programs and projects and provides a quantitative overview of the post-Phase II award patterns that correspond with each mission directorate at NASA Glenn Research Center (GRC). In recent years, one of NASA's goals has been to not only transfer SBIR technologies to commercial industries, but to ensure that NASA mission directorates incorporate SBIR technologies into their program and project activities. Before incorporating technologies into MD programs, it is important to understand each mission directorate structure because each directorate has different objectives and needs. The directorate program structures follow.

  4. Identifying Opportunities for Peer Learning: An Observational Study of Medical Students on Clinical Placements.

    PubMed

    Tai, Joanna H; Canny, Benedict J; Haines, Terry P; Molloy, Elizabeth K

    2017-01-01

    observation and feedback on the ward; discussion during lunch) situations in clinical education and find it useful. The educator is crucial in fostering PAL through providing opportunities for learners to practice together and in helping to moderate discussions about quality of performance. Student engagement in PAL may reduce passivity commonly reported in clinical rotations. Further directions for research into PAL in clinical education are identified along with potential strategies that may maximize the benefits of peer to peer learning.

  5. The state of the art and future opportunities for using longitudinal n-of-1 methods in health behaviour research: a systematic literature overview.

    PubMed

    McDonald, Suzanne; Quinn, Francis; Vieira, Rute; O'Brien, Nicola; White, Martin; Johnston, Derek W; Sniehotta, Falko F

    2017-12-01

    n-of-1 studies test hypotheses within individuals based on repeated measurement of variables within the individual over time. Intra-individual effects may differ from those found in between-participant studies. Using examples from a systematic review of n-of-1 studies in health behaviour research, this article provides a state of the art overview of the use of n-of-1 methods, organised according to key methodological considerations related to n-of-1 design and analysis, and describes future challenges and opportunities. A comprehensive search strategy (PROSPERO:CRD42014007258) was used to identify articles published between 2000 and 2016, reporting observational or interventional n-of-1 studies with health behaviour outcomes. Thirty-nine articles were identified which reported on n-of-1 observational designs and a range of n-of-1 interventional designs, including AB, ABA, ABABA, alternating treatments, n-of-1 randomised controlled trial, multiple baseline and changing criterion designs. Behaviours measured included treatment adherence, physical activity, drug/alcohol use, sleep, smoking and eating behaviour. Descriptive, visual or statistical analyses were used. We identify scope and opportunities for using n-of-1 methods to answer key questions in health behaviour research. n-of-1 methods provide the tools needed to help advance theoretical knowledge and personalise/tailor health behaviour interventions to individuals.

  6. The Python Project: A Unique Model for Extending Research Opportunities to Undergraduate Students

    PubMed Central

    Harvey, Pamela A.; Wall, Christopher; Luckey, Stephen W.; Langer, Stephen

    2014-01-01

    Undergraduate science education curricula are traditionally composed of didactic instruction with a small number of laboratory courses that provide introductory training in research techniques. Research on learning methodologies suggests this model is relatively ineffective, whereas participation in independent research projects promotes enhanced knowledge acquisition and improves retention of students in science. However, availability of faculty mentors and limited departmental budgets prevent the majority of students from participating in research. A need therefore exists for this important component in undergraduate education in both small and large university settings. A course was designed to provide students with the opportunity to engage in a research project in a classroom setting. Importantly, the course collaborates with a sponsor's laboratory, producing a symbiotic relationship between the classroom and the laboratory and an evolving course curriculum. Students conduct a novel gene expression study, with their collective data being relevant to the ongoing research project in the sponsor's lab. The success of this course was assessed based on the quality of the data produced by the students, student perception data, student learning gains, and on whether the course promoted interest in and preparation for careers in science. In this paper, we describe the strategies and outcomes of this course, which represents a model for efficiently providing research opportunities to undergraduates. PMID:25452492

  7. [Improved opportunities for the identification of people with a migrant background for mortality research using the example of Bremen].

    PubMed

    Makarova, N; Reiss, K; Zeeb, H; Razum, O; Spallek, J

    2013-06-01

    19.6% of Germany's population has a "migrant" background. Comprehensive epidemiological research on health and health development of this large, heterogeneous and increasingly important population group in Germany is still deficient. There is a lack of results on mortality and morbidity, particularly concerning chronic diseases and disease processes. The aim of this paper is to combine and to compare already applied methods with new methodological approaches for determining the vital status and the mortality of immigrants from Turkey and the former Soviet Union. For this purpose we used data from the state of Bremen (666 709 residents, last update 2010). We examined 2 methodological aspects: (i) possibilities for identifying immigrant background in the data of residents' registration office with different methods (onomastic, toponomastic, etc.) and (ii) opportunities for record linkage of the obtained data with the Bremen mortality index. Immigrants from Turkey and the former Soviet Union were successfully identified in databases of the residents' registration office by a combination of different methods. The combination of different methodological approaches proved to be considerably better than using one method only. Through the application of a name-based algorithm we found that Turkish immigrants comprise 6.9% of the total population living in Bremen. By combining the variables "citizenship" and "country of birth" the total population proportion of immigrants from the former Soviet Union was found to be 5%. We also identified the deceased immigrant population in Bremen. The information obtained from residents' registration office could be successfully linked by death register number with the data of the Bremen mortality index. This information can be used in further detailed mortality analyses. The results of this analysis show the existing opportunities to consider the heterogeneity of the German population in mortality research, especially by means of

  8. The Florida Prostate Cancer Research Training Opportunities for Outstanding Leaders (ReTOOL) Program: Creating Opportunities for Minority HBCU Students

    DTIC Science & Technology

    2015-03-01

    designated by other documentation. REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of...have also established an Advanced ReTOOL program, which will provide additional summer training experiences and post -baccalaureate opportunities to...address cultural appropriateness of research conceptualization, design and implementation; (3) provide culturally appropriate cancer prevention, screening

  9. Social network characteristics and HIV vulnerability among transgender persons in San Salvador: identifying opportunities for HIV prevention strategies.

    PubMed

    Barrington, Clare; Wejnert, Cyprian; Guardado, Maria Elena; Nieto, Ana Isabel; Bailey, Gabriela Paz

    2012-01-01

    The purpose of this study is to improve understanding of HIV vulnerability and opportunities for HIV prevention within the social networks of male-to-female transgender persons in San Salvador, El Salvador. We compare HIV prevalence and behavioral data from a sample of gay-identified men who have sex with men (MSM) (n = 279), heterosexual or bisexual identified MSM (n = 229) and transgender persons (n = 67) recruited using Respondent Driven Sampling. Transgender persons consistently reported higher rates of HIV risk behavior than the rest of the study population and were significantly more likely to be involved in sex work. While transgender persons reported the highest rates of exposure to HIV educational activities they had the lowest levels of HIV-related knowledge. Transgender respondents' social networks were homophilous and efficient at recruiting other transgender persons. Findings suggest that transgender social networks could provide an effective and culturally relevant opportunity for HIV prevention efforts in this vulnerable population.

  10. Social Network Characteristics and HIV Vulnerability Among Transgender Persons in San Salvador: Identifying Opportunities for HIV Prevention Strategies

    PubMed Central

    Barrington, Clare; Wejnert, Cyprian; Guardado, Maria Elena; Nieto, Ana Isabel; Bailey, Gabriela Paz

    2013-01-01

    The purpose of this study is to improve understanding of HIV vulnerability and opportunities for HIV prevention within the social networks of male-to-female transgender persons in San Salvador, El Salvador. We compare HIV prevalence and behavioral data from a sample of gay-identified men who have sex with men (MSM) (n = 279), heterosexual or bisexual identified MSM (n = 229) and transgender persons (n = 67) recruited using Respondent Driven Sampling. Transgender persons consistently reported higher rates of HIV risk behavior than the rest of the study population and were significantly more likely to be involved in sex work. While transgender persons reported the highest rates of exposure to HIV educational activities they had the lowest levels of HIV-related knowledge. Transgender respondents’ social networks were homophilous and efficient at recruiting other transgender persons. Findings suggest that transgender social networks could provide an effective and culturally relevant opportunity for HIV prevention efforts in this vulnerable population. PMID:21538082

  11. Opportunities for research in space life sciences aboard commercial suborbital flights.

    PubMed

    Wagner, Erika B; Charles, John B; Cuttino, Charles Marsh

    2009-11-01

    The emergence of commercial suborbital spaceflight offers a wide range of new research and development opportunities for those in the space life sciences. Large numbers of diverse flyers, frequent re-flights, and flexible operations provide a fertile ground for both basic and applied science, as well as technology demonstrations. This commentary explores some of the unique features available to the space life science community and encourages engagement with commercial developers and operators during the design phase to help optimize platform designs and operations for future research.

  12. Opportunities for Materials Science and Biological Research at the OPAL Research Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kennedy, S. J.

    Neutron scattering techniques have evolved over more than 1/2 century into a powerful set of tools for determination of atomic and molecular structures. Modern facilities offer the possibility to determine complex structures over length scales from {approx}0.1 nm to {approx}500 nm. They can also provide information on atomic and molecular dynamics, on magnetic interactions and on the location and behaviour of hydrogen in a variety of materials. The OPAL Research Reactor is a 20 megawatt pool type reactor using low enriched uranium fuel, and cooled by water. OPAL is a multipurpose neutron factory with modern facilities for neutron beam research,more » radioisotope production and irradiation services. The neutron beam facility has been designed to compete with the best beam facilities in the world. After six years in construction, the reactor and neutron beam facilities are now being commissioned, and we will commence scientific experiments later this year. The presentation will include an outline of the strengths of neutron scattering and a description of the OPAL research reactor, with particular emphasis on it's scientific infrastructure. It will also provide an overview of the opportunities for research in materials science and biology that will be possible at OPAL, and mechanisms for accessing the facilities. The discussion will emphasize how researchers from around the world can utilize these exciting new facilities.« less

  13. Content analysis as a means of exploring research opportunities from a conference programme.

    PubMed

    Fourie, Ina

    2012-09-01

    Health librarians should keep up-to-date in a dynamic environment and accept the importance of continuing personal development (CPD) and growth in their critical reflection and creative thinking skills. They also need to acknowledge the potential value of research activity and the challenges of ongoing improvement and development. Conference programmes may prove a useful source of stimulation, especially if supplemented by creativity techniques, action research and the ideal of 'finding flow'. The article analyses the themes and papers presented at the 10th International Conference on International Medical Librarianship (ICML) to identify opportunities for further research, literature reviews, assessment of practices and services, etc. Content analysis approach to conference papers and suggestions for further action including supplementing with techniques of creativity and group input. A fairly extensive list of further actions (although not intended to be exhaustive) is suggested for the sixteen conference themes. Although subjective, the list might help to stimulate growth in research on health librarianship and demonstrate how one source of stimulation--conference programmes (regularly presented to medical library communities)--can be used. Content analysis has proven a constructive means of generating research questions from a conference programme. Content analysis and other methods aimed at stimulating creative and progressive thinking, including brainstorming, force field analysis, De Bono's 6 hats, creative swiping and creative visualisation, may prove equally useful and require further investigation. To ensure an ongoing cycle, these can be linked to action research. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.

  14. Challenges and opportunities in building health research capacity in Tanzania: a case of the National Institute for Medical Research.

    PubMed

    Magesa, Stephen M; Mwape, Bonard; Mboera, Leonard E G

    2011-12-01

    Capacity building is considered a priority for health research institutions in developing countries to achieve the Millennium Development Goals by 2015. However, in many countries including Tanzania, much emphasis has been directed towards human resources for health with the total exclusion of human resources for health research. The objective of this study was to systematically investigate the capacity building process for the Tanzanian National Institute for Medical Research (NIMR) over a 30-year period and identify the challenges and opportunities in creating a critical mass of multi-disciplinary research scientists that is required for achieving the intended health benefits. A desk review of personnel database was conducted for information covering 1980-2009 on academic qualifications, training, research experience and research output. The current staff curriculum vitae (CV) were reviewed to gather information on researchers' employment record, training, training support, area of expertise and scientific output. Interviews were conducted with a cross section of researchers on capacity development aspects using a self-administered questionnaire. In-depth interviews were also conducted with the current and former NIMR Management to seek information on capacity development challenges. A review was also done on staff personal files, annual reports, strategic plans and other occasional documents. A total of 163 CV were assessed; of these, 76.7% (125) were for Research Scientists (RS), 20.9% (34) Laboratory Technologists (LT) and 2.4% (4) for System Analysts. The Institute had 13 research scientists upon its establishment. Since 1980, NIMR has recruited a total of 185 Research Scientists. By 2009, NIMR had a total scientific workforce of 170 staff (RS= 82.4%; LT= 17.6%). Of the 140 RSs, 37 (26.4%), were first degree; 77 (55.5%) second degree while 26 (18.6%) were PhD degree holders. Of the total of 78 researchers interviewed, 55 (70.5%) indicated to have accessed

  15. Active colloids with collective mobility status and research opportunities.

    PubMed

    Zhang, Jie; Luijten, Erik; Grzybowski, Bartosz A; Granick, Steve

    2017-09-18

    The collective mobility of active matter (self-propelled objects that transduce energy into mechanical work to drive their motion, most commonly through fluids) constitutes a new frontier in science and achievable technology. This review surveys the current status of the research field, what kinds of new scientific problems can be tackled in the short term, and what long-term directions are envisioned. We focus on: (1) attempts to formulate design principles to tailor active particles; (2) attempts to design principles according to which active particles interact under circumstances where particle-particle interactions of traditional colloid science are augmented by a family of nonequilibrium effects discussed here; (3) attempts to design intended patterns of collective behavior and dynamic assembly; (4) speculative links to equilibrium thermodynamics. In each aspect, we assess achievements, limitations, and research opportunities.

  16. Optical Science and Engineering. New Directions and Opportunities in Research and Education. NSF Workshop (Arlington, VA, May 23-24, 1994).

    ERIC Educational Resources Information Center

    National Science Foundation, Arlington, VA.

    The National Science Foundation (NSF) workshop on Optical Science and Engineering was organized to examine approaches NSF could use to identify opportunities in optical science, engineering, and education that meet both the mission of NSF and its broader national goals. The workshop participants identified opportunities where optical science and…

  17. SOARS: Significant Opportunities in Atmospheric Research and Science

    NASA Astrophysics Data System (ADS)

    Windham, T. L.; Hagan, M. E.

    2001-05-01

    SOARS, a model program, has developed a unique mutli-year mentoring and learning community to support, teach, and guide college students from diverse backgrounds. SOARS is dedicated to increasing the number of African American, American Indian, and Hispanic/Latino students enrolled in master's and doctoral degree programs in the atmospheric and related sciences with the goal of supporting the development of a diverse, internationally competitive and globally engaged workforce within the scientific community. Since its 1996 inception, 51 undergraduates have participated. All 51 completed or are on schedule to complete their undergraduate degrees with a major in an atmospheric or related science. Currently 17 protégés are in graduate programs. Eight have completed M.S. degrees; two are Ph.D. candidates. SOARS has a retention rate of 82 percent. The SOARS learning community provides multi-year programing for protégés that includes educational and research opportunities, mentoring, career counseling and guidance, and the possibility of financial support for a graduate level program. Protégés spend their summers at NCAR, participate in ongoing research projects, an eight week scientific writing and communication workshop, and scientific seminars. They benefit from long-term mentoring from respected scientists and professionals, learn about career opportunities, practice leadership and are encouraged to complete a graduate program in an atmospheric or related science. In this presentation we highlight the SOARS program structure and objectives with particular emphasis on the mentoring model that is fundamental to SOARS. We conclude with a summary of SOARS protégés' contributions to the broader scientific community which include oral and poster presentations at national and regional scientific conferences, as well as co-authorship of refereed journal articles.

  18. Preventable injury deaths: identifying opportunities to improve timeliness and reach of emergency healthcare services in New Zealand.

    PubMed

    Lilley, Rebbecca; Kool, Bridget; Davie, Gabrielle; de Graaf, Brandon; Ameratunga, Shanthi N; Reid, Pararangi; Civil, Ian; Dicker, Bridget; Branas, Charles C

    2017-02-09

    Traumatic injury is a leading cause of premature death and health loss in New Zealand. Outcomes following injury are very time sensitive, and timely access of critically injured patients to advanced hospital trauma care services can improve injury survival. This cross-sectional study will investigate the epidemiology and geographic location of prehospital fatal injury deaths in relation to access to prehospital emergency services for the first time in New Zealand. Electronic Coronial case files for the period 2008-2012 will be reviewed to identify cases of prehospital fatal injury across New Zealand. The project will combine epidemiological and geospatial methods in three research phases: (1) identification, enumeration, description and geocoding of prehospital injury deaths using existing electronic injury data sets; (2) geocoding of advanced hospital-level care providers and emergency land and air ambulance services to determine the current theoretical service coverage in a specified time period and (3) synthesising of information from phases I and II using geospatial methods to determine the number of prehospital injury deaths located in areas without timely access to advanced-level hospital care. The findings of this research will identify opportunities to optimise access to advanced-level hospital care in New Zealand to increase the chances of survival from serious injury. The resulting epidemiological and geospatial analyses will represent an advancement of knowledge for injury prevention and health service quality improvement towards better patient outcomes following serious injury in New Zealand and similar countries. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. Engaging High School Science Teachers in Field-Based Seismology Research: Opportunities and Challenges

    NASA Astrophysics Data System (ADS)

    Long, M. D.

    2015-12-01

    Research experiences for secondary school science teachers have been shown to improve their students' test scores, and there is a substantial body of literature about the effectiveness of RET (Research Experience for Teachers) or SWEPT (Scientific Work Experience Programs for Teachers) programs. RET programs enjoy substantial support, and several opportunities for science teachers to engage in research currently exist. However, there are barriers to teacher participation in research projects; for example, laboratory-based projects can be time consuming and require extensive training before a participant can meaningfully engage in scientific inquiry. Field-based projects can be an effective avenue for involving teachers in research; at its best, earth science field work is a fun, highly immersive experience that meaningfully contributes to scientific research projects, and can provide a payoff that is out of proportion to a relatively small time commitment. In particular, broadband seismology deployments provide an excellent opportunity to provide teachers with field-based research experience. Such deployments are labor-intensive and require large teams, with field tasks that vary from digging holes and pouring concrete to constructing and configuring electronics systems and leveling and orienting seismometers. A recently established pilot program, known as FEST (Field Experiences for Science Teachers) is experimenting with providing one week of summer field experience for high school earth science teachers in Connecticut. Here I report on results and challenges from the first year of the program, which is funded by the NSF-CAREER program and is being run in conjunction with a temporary deployment of 15 seismometers in Connecticut, known as SEISConn (Seismic Experiment for Imaging Structure beneath Connecticut). A small group of teachers participated in a week of field work in August 2015 to deploy seismometers in northern CT; this experience followed a visit of the

  20. How do NHS organisations plan research capacity development? Strategies, strengths, and opportunities for improvement.

    PubMed

    Gee, Melanie; Cooke, Jo

    2018-03-22

    Research that is integral into a 'learning healthcare system' can promote cost effective services and knowledge creation. As such, research is defined as a 'core function' in UK health service organisations, and is often planned through research and development (R&D) strategies that aim to promote research activity and research capacity development (RCD). The discussion focuses around the content of ten R&D strategies for healthcare organisations in England and Scotland, with respect to RCD. These organisations were engaged with a research interest network called ACORN (Addressing Organisational Capacity to do Research Network) that included two Scottish Health Boards, four community and mental health trusts, two provincial district hospitals, and two teaching hospitals. We undertook a thematic documentary analysis of the R&D strategies which identified 11 'core activities' of RCD. The potential for building research capacity in these 'core activities' was established by reviewing them through the lens of a RCD framework. Core activities aimed to 'hard wire' RCD into health organisations. They demonstrated a complex interplay between developing a strong internal organisational infrastructure, and supporting individual career planning and skills development, in turn enabled by organisational processes. They also included activities to build stronger inter-organisational relationships and networks. Practitioner, manager and patient involvement was a cross cutting theme. The potential to demonstrate progress was included in plans through monitoring activity across all RCD principles. Strategies were primarily aimed at research production rather than research use. Developing 'actionable dissemination' was poorly addressed in the strategies, and represents an area for improvement. We describe strengths of RCD planning activities, and opportunities for improvement. We explore how national policy and research funders can influence health systems' engagement in research.

  1. Survived so what? Identifying priorities for research with children and families post-paediatric intensive care unit.

    PubMed

    Manning, Joseph C; Hemingway, Pippa; Redsell, Sarah A

    2018-03-01

    The involvement of patients and the public in the development, implementation and evaluation of health care services and research is recognized to have tangible benefits in relation to effectiveness and credibility. However, despite >96% of children and young people surviving critical illness or injury, there is a paucity of published reports demonstrating their contribution to informing the priorities for aftercare services and outcomes research. We aimed to identify the service and research priorities for Paediatric Intensive Care Unit survivors with children and young people, their families and other stakeholders. We conducted a face-to-face, multiple-stakeholder consultation event, held in the Midlands (UK), to provide opportunities for experiences, views and priorities to be elicited. Data were gathered using write/draw and tell and focus group approaches. An inductive content analytical approach was used to categorize and conceptualize feedback. A total of 26 individuals attended the consultation exercise, including children and young people who were critical care survivors; their siblings; parents and carers; health professionals; academics; commissioners; and service managers. Consultation findings indicated that future services, interventions and research must be holistic and family-centred. Children and young people advisors reported priorities that focused on longer-term outcomes, whereas adult advisors identified priorities that mapped against the pathways of care. Specific priorities included developing and testing interventions that address unmet communication and information needs. Furthermore, initiatives to optimize the lives and longer-term functional and psycho-social outcomes of Paediatric Intensive Care Unit survivors were identified. This consultation exercise provides further evidence of the value of meaningful patient and public involvement in identifying the priorities for research and services for Paediatric Intensive Care Unit survivors

  2. Translating Alcohol Research: Opportunities and Challenges.

    PubMed

    Batman, Angela M; Miles, Michael F

    2015-01-01

    Alcohol use disorder (AUD) and its sequelae impose a major burden on the public health of the United States, and adequate long-term control of this disorder has not been achieved. Molecular and behavioral basic science research findings are providing the groundwork for understanding the mechanisms underlying AUD and have identified multiple candidate targets for ongoing clinical trials. However, the translation of basic research or clinical findings into improved therapeutic approaches for AUD must become more efficient. Translational research is a multistage process of stream-lining the movement of basic biomedical research findings into clinical research and then to the clinical target populations. This process demands efficient bidirectional communication across basic, applied, and clinical science as well as with clinical practitioners. Ongoing work suggests rapid progress is being made with an evolving translational framework within the alcohol research field. This is helped by multiple interdisciplinary collaborative research structures that have been developed to advance translational work on AUD. Moreover, the integration of systems biology approaches with collaborative clinical studies may yield novel insights for future translational success. Finally, appreciation of genetic variation in pharmacological or behavioral treatment responses and optimal communication from bench to bedside and back may strengthen the success of translational research applications to AUD.

  3. Research fronts analysis : A bibliometric to identify emerging fields of research

    NASA Astrophysics Data System (ADS)

    Miwa, Sayaka; Ando, Satoko

    Research fronts analysis identifies emerging areas of research through observing co-clustering in highly-cited papers. This article introduces the concept of research fronts analysis, explains its methodology and provides case examples. It also demonstrates developing research fronts in Japan by looking at the past winners of Thomson Reuters Research Fronts Awards. Research front analysis is currently being used by the Japanese government to determine new trends in science and technology. Information professionals can also utilize this bibliometric as a research evaluation tool.

  4. 76 FR 76743 - Government-Owned Inventions; Licensing and Collaborative Research Opportunity: Chemotoxins for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ...; Licensing and Collaborative Research Opportunity: Chemotoxins for Targeted Treatment of Diseased Cells... (aka ``chemotoxins'') to preferentially and specifically eliminate chemokine receptor-expressing cells... used to cause inflammation to specifically target immune cells to increase immunogenicity for malignant...

  5. Research and career opportunities in the geophysical sciences for physics students

    NASA Astrophysics Data System (ADS)

    Nyblade, Andrew

    2008-10-01

    The field of geophysics involves using most branches of physics to investigate the physical structure and process that characterize the solid and fluid parts of our planet. Major advances in geophysics have come about from physicists crossing disciplinary boundaries and using their skills and knowledge to address first-order problems about the nature and structure of our planet and how the planet has changed over time. Indeed, some of the largest scientific breakthroughs in geophysics have come from physicists. As a way to introduce students to the field of geophysics and to provide them with information about research and career opportunities in geophysics, this talk will focus on one area of geophysics, seismology. This is an area of geophysics that has not only been instrumental in advancing our understanding of solid Earth structure and processes, but one that also has an applied side used for oil, gas and mineral exploration, as well as for environmental work. Examples of research projects involving seismic wave propagation and tomographic imaging will be presented, along the short descriptions of career opportunities in industry, government and academic institutions. In collaboration with Solomon Bililign, North Carolina A&T State University.

  6. Barriers, Opportunities, and Strategies for Urban Ecosystem ...

    EPA Pesticide Factsheets

    Urban ecosystem restoration can be especially difficult to accomplish because of complications like industrial pollutants, population density, infrastructure, and expense, however, the unique opportunities in urban settings, including the potential to provide benefits to many people, can make urban restoration especially rewarding. The success of urban restoration projects—even those focused primarily on ecological targets—depends on incorporating the findings of social research, though that research is relatively rare. This work attempts to fill that gap by presenting barriers, opportunities, and strategies for restoration projects in urban settings. Building from interviews with restoration managers involved in a suite of aquatic restoration projects in Rhode Island, we contribute to the learning axis of adaptive management by identifying and synthesizing the lessons learned from managers’ work in urban settings. We then consider how managers can design creative solutions to accomplish restoration goals by thinking more broadly about the multiple social or institutional, biophysical, and discursive dimensions of barriers to and opportunities for urban restoration. This report describes the results from 27 interviews with restoration managers, and informs managers about barriers, opportunities, and strategies for restoration in urban settings.

  7. "Geriatricizing" Hospitalists: Identifying Educational Opportunities

    ERIC Educational Resources Information Center

    Friedman, Susan M.; Gillespie, Suzanne M.; Medina-Walpole, Annette M.; Caprio, Thomas V.; Karuza, Jurgis; McCann, Robert M.

    2013-01-01

    The objective of this study was to identify differences between geriatricians and hospitalists in caring for hospitalized older adults, so as to inform faculty development programs that have the goal of improving older patient care. Eleven hospitalists and 13 geriatricians were surveyed regarding knowledge, confidence, and practice patterns in…

  8. Promotion in Call Centres: Opportunities and Determinants

    ERIC Educational Resources Information Center

    Gorjup, Maria Tatiana; Valverde, Mireia; Ryan, Gerard

    2008-01-01

    Purpose: The purpose of this paper is to examine the quality of jobs in call centres by focusing on the opportunities for promotion in this sector. More specifically, the research questions focus on discovering whether promotion is common practise in the call centre sector and on identifying the factors that affect this.…

  9. Contract Funding Opportunities Available for Innovative SBIR Development | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    Does your small business need early-stage financing to take its cancer research to the next level? The National Cancer Institute Small Business Innovation Research (NCI SBIR) Development Center has released $5 million for new contract funding opportunities to support cancer research and technology development in key emerging areas of need. The NCI SBIR can help you finance and advance innovations in cancer prevention, diagnosis, treatment, and basic research.

  10. Short communication: Identifying challenges and opportunities for improved nutrient management through the USDA's Dairy Agroecosystem Working Group.

    PubMed

    Holly, M A; Kleinman, P J; Bryant, R B; Bjorneberg, D L; Rotz, C A; Baker, J M; Boggess, M V; Brauer, D K; Chintala, R; Feyereisen, G W; Gamble, J D; Leytem, A B; Reed, K F; Vadas, P A; Waldrip, H M

    2018-04-25

    Nutrient management on US dairy farms must balance an array of priorities, some of which conflict. To illustrate nutrient management challenges and opportunities across the US dairy industry, the USDA Agricultural Research Service Dairy Agroecosystems Working Group (DAWG) modeled 8 confinement and 2 grazing operations in the 7 largest US dairy-producing states using the Integrated Farm System Model (IFSM). Opportunities existed across all of the dairies studied to increase on-farm feed production and lower purchased feed bills, most notably on large dairies (>1,000 cows) with the highest herd densities. Purchased feed accounted for 18 to 44% of large dairies' total operating costs compared with 7 to 14% on small dairies (<300 milk cows) due to lower stocking rates. For dairies with larger land bases, in addition to a reduction in environmental impact, financial incentives exist to promote prudent nutrient management practices by substituting manure nutrients or legume nutrients for purchased fertilizers. Environmental priorities varied regionally and were principally tied to facility management for dry-lot dairies of the semi-arid western United States (ammonia-N emissions), to manure handling and application for humid midwestern and eastern US dairies (nitrate-N leaching and P runoff), and pasture management for dairies with significant grazing components (nitrous oxide emissions). Many of the nutrient management challenges identified by DAWG are beyond slight modifications in management and require coordinated solutions to ensure an environmentally and economically sustainable US dairy industry. The Authors. Published by FASS Inc. and Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

  11. The Virtual Poster Showcase: Opportunities for students to present their research from anywhere

    NASA Astrophysics Data System (ADS)

    Asher, P. M.; Furukawa, H.; Williams, B. M.; Holm Adamec, B.

    2015-12-01

    Although many students conduct research with faculty in organized summer programs or as part of their course work or their degree work, they often face barriers to traveling to present that research, especially at national or international conferences. This is especially true for students who are members of underrepresented minority populations and students studying outside of the United States. A new and exciting opportunity for undergraduate as well as graduate students to showcase their work is now available. AGU piloted three opportunities for an undergraduate and graduate virtual poster showcase in the fall of 2015. Student participants were recruited from a diverse array of groups including minority-serving organizations, two-year colleges, and internship programs at federal agencies and national laboratories. Students uploaded an abstract, poster, and short video explain their research, and then participated in Q&A sessions with peers as well as expert judges. This presentation will share characteristics of participating groups, lessons learned from this new program, and preliminary evaluation findings as well as plans for the future.

  12. Research and Practice Opportunities at the Intersection of Health Education, Health Behavior, and Genomics

    ERIC Educational Resources Information Center

    Wang, Catharine; Bowen, Deborah J.; Kardia, Sharon L. R.

    2005-01-01

    Researchers and practitioners in health behavior and health education (HBHE) can play a pivotal leadership role in the integration of genomic advances to improve the public's health. The purpose of this article is to outline research and practice opportunities at the intersection of genomics and HBHE. We begin this article by briefly summarizing…

  13. Research opportunities in human behavior and performances

    NASA Technical Reports Server (NTRS)

    Christensen, J. M.; Talbot, J. M.

    1985-01-01

    The NASA research program in the biological and medical aspects of space flight includes investigations of human behavior and performance. The research focuses on psychological and psychophysiological responses to operational and environmental stresses and demands of spaceflight, and encompasses problems in perception, cognition, motivation, psychological stability, small group dynamics, and performance. The primary objective is to acquire the knowledge and methodology to aid in achieving high productivity and essential psychological support of space and ground crews in the Space Shuttle and space station programs. The Life Sciences Research Office (LSRO) of the Federation of American Societies for Experimental Biology reviewed its program in psychology and identified its research for future program planning to be in line with NASA's goals.

  14. Logistical Challenges and Opportunities for Conducting Peer Nomination Research in Schools.

    PubMed

    Mayeux, Lara; Kraft, Caroline

    2017-09-01

    Although conducting psychological research within schools has always required effort, persistence, and the careful navigation of various interests, there is a consensus among child and adolescent researchers that, over the past 2 decades, it has become increasingly difficult to collect data within schools. In this chapter, we lay out common and consistent difficulties, frustrations, and obstacles that researchers face when attempting to conduct peer nomination research in schools. Many of these difficulties are faced not only by researchers conducting peer nominations but by any investigator attempting to do school-based research, and we discuss these issues more broadly. We also focus on the specific challenges associated with sociometric methods. We present suggestions and solutions for overcoming these issues and consider ways that researchers can give back to schools and establish long-term partnerships that benefit the students, teachers, and administrators of participating schools, as well as the researchers themselves. Such partnerships have the potential to make data collection easier and to open doors to new research opportunities. © 2017 Wiley Periodicals, Inc.

  15. Identifying and Analyzing Federal Government Market Opportunities for OpalSoft

    DTIC Science & Technology

    2004-09-01

    OPPORTUNITIES, AND THREATS ( SWOT ) ANALYSIS......................................................................................13 1. Strengths...xiii LIST OF TABLES Table 1. SWOT Analysis...of industries to include Fortune 500 companies. Current key clients are Amkor, Symantec, Unisys Corporation, Apple Computers, Palm, Inc., and

  16. Constraints and Opportunities with Interview Transcription: Towards Reflection in Qualitative Research

    PubMed Central

    Oliver, Daniel G.; Serovich, Julianne M.; Mason, Tina L.

    2006-01-01

    In this paper we discuss the complexities of interview transcription. While often seen as a behind-the-scenes task, we suggest that transcription is a powerful act of representation. Transcription is practiced in multiple ways, often using naturalism, in which every utterance is captured in as much detail as possible, and/or denaturalism, in which grammar is corrected, interview noise (e.g., stutters, pauses, etc.) is removed and nonstandard accents (i.e., non-majority) are standardized. In this article, we discuss the constraints and opportunities of our transcription decisions and point to an intermediate, reflective step. We suggest that researchers incorporate reflection into their research design by interrogating their transcription decisions and the possible impact these decisions may have on participants and research outcomes. PMID:16534533

  17. NBIC Job Opportunities

    Science.gov Websites

    | NBIC Research & Development | NBIC News | Home Job Opportunities NBIC Home|NBIC Overview | Collaborators | Citation | Disclaimer | Credits | Job Opportunities Contact us: nbic@ballastreport.org

  18. Patient and Family Engagement in the ICU: Untapped Opportunities and Under Recognized Challenges.

    PubMed

    Burns, Karen E A; Misak, Cheryl; Herridge, Margaret; Meade, Maureen O; Oczkowski, Simon

    2018-04-06

    The call for meaningful patient and family engagement in healthcare and research is gaining impetus. Healthcare institutions and research funding agencies increasingly encourage clinicians and researchers to work actively with patients and their families to advance clinical care and research. Engagement is increasingly mandated by healthcare organizations and is becoming a prerequisite for research funding. In this article, we review the rationale and the current state of patient and family engagement in patient care and research in the intensive care unit (ICU). We identify opportunities to strengthen engagement in patient care by promoting greater patient and family involvement in care delivery and supporting their participation in shared decision-making. We also identify challenges related to patient willingness to engage, barriers to participation, participant risks, and participant expectations. To advance engagement, clinicians and researchers can develop the science behind engagement in the ICU context and demonstrate its impact on patient and process-related outcomes. Additionally, we provide practical guidance on how to engage, highlight features of successful engagement strategies, and identify areas for future research. At present, enormous opportunities remain to enhance engagement across the continuum of ICU care and research.

  19. Building Collaborative Research Opportunities into Study Abroad Programs: A Case Study from Panama

    ERIC Educational Resources Information Center

    Solís, Patricia; Price, Marie; Adames de Newbill, María

    2015-01-01

    As universities increase their international study opportunities, enormous potential exists to create geography field courses that provide undergraduates and graduate students with primary research experience and intercultural collaboration. This paper draws from our experience leading a two-week collaborative field course in Panama. We outline…

  20. Applications of monsoon research: Opportunities to inform decisionmaking and reduce regional vulnerability

    NASA Astrophysics Data System (ADS)

    Ray, A. J.; Garfin, G. M.; Wilder, M.; Lenart, M.; Vásquez-León, M.; Comrie, A. C.

    2007-05-01

    This presentation will describe ongoing efforts to understand interactions between the North American Monsoon and society, in order to develop applications for monsoon research in a highly complex, multicultural and binational region. The North American Monsoon is an annual precipitation regime that begins in early June in Mexico and progresses northward to the southwestern United States. The region includes stakeholders in large urban complexes, productive agricultural areas, and sparsely populated arid and semi-arid ecosystems. The political, cultural, and socioeconomic divisions between the U.S. and Mexico create a broad range of sensitivities to climate variability as well as capacities to use forecasts and other information to cope with climate. We will highlight methodologies to link climate science with society and analyze opportunities for monsoon science to benefit society in four sectors: natural hazards management, agriculture, public health, and water management. We present a synthesized list of stakeholder needs and a calendar of decisions to help scientists link user needs to potential forecasts and products. To ensure usability of forecasts and other research products, we recommend iterative scientist-stakeholder interactions, through integrated assessments. These knowledge- exchange interactions can improve the capacity for stakeholders to use forecasts thoughtfully and inform the development of research, and for the research community to obtain feedback on climate-related products and receive insights to guide research direction. We expect that integrated assessments can capitalize on the opportunities for monsoon science to inform decisionmaking, in the best instances, reduce regional climate vulnerabilities and enhance regional sustainability

  1. Identifying Opportunities for Grade One Children to Acquire Foundational Number Sense: Developing a Framework for Cross Cultural Classroom Analyses

    ERIC Educational Resources Information Center

    Andrews, Paul; Sayers, Judy

    2015-01-01

    It is known that an appropriately developed foundational number sense (FONS), or the ability to operate flexibly with number and quantity, is a powerful predictor of young children's later mathematical achievement. However, until now not only has FONS been definitionally elusive but instruments for identifying opportunities for children to acquire…

  2. Landfalling Tropical Cyclones: Forecast Problems and Associated Research Opportunities

    USGS Publications Warehouse

    Marks, F.D.; Shay, L.K.; Barnes, G.; Black, P.; Demaria, M.; McCaul, B.; Mounari, J.; Montgomery, M.; Powell, M.; Smith, J.D.; Tuleya, B.; Tripoli, G.; Xie, Lingtian; Zehr, R.

    1998-01-01

    The Fifth Prospectus Development Team of the U.S. Weather Research Program was charged to identify and delineate emerging research opportunities relevant to the prediction of local weather, flooding, and coastal ocean currents associated with landfalling U.S. hurricanes specifically, and tropical cyclones in general. Central to this theme are basic and applied research topics, including rapid intensity change, initialization of and parameterization in dynamical models, coupling of atmospheric and oceanic models, quantitative use of satellite information, and mobile observing strategies to acquire observations to evaluate and validate predictive models. To improve the necessary understanding of physical processes and provide the initial conditions for realistic predictions, a focused, comprehensive mobile observing system in a translating storm-coordinate system is required. Given the development of proven instrumentation and improvement of existing systems, three-dimensional atmospheric and oceanic datasets need to be acquired whenever major hurricanes threaten the United States. The spatial context of these focused three-dimensional datasets over the storm scales is provided by satellites, aircraft, expendable probes released from aircraft, and coastal (both fixed and mobile), moored, and drifting surface platforms. To take full advantage of these new observations, techniques need to be developed to objectively analyze these observations, and initialize models aimed at improving prediction of hurricane track and intensity from global-scale to mesoscale dynamical models. Multinested models allow prediction of all scales from the global, which determine long- term hurricane motion to the convective scale, which affect intensity. Development of an integrated analysis and model forecast system optimizing the use of three-dimensional observations and providing the necessary forecast skill on all relevant spatial scales is required. Detailed diagnostic analyses of these

  3. Artificial intelligence and design: Opportunities, research problems and directions

    NASA Technical Reports Server (NTRS)

    Amarel, Saul

    1990-01-01

    The issues of industrial productivity and economic competitiveness are of major significance in the U.S. at present. By advancing the science of design, and by creating a broad computer-based methodology for automating the design of artifacts and of industrial processes, we can attain dramatic improvements in productivity. It is our thesis that developments in computer science, especially in Artificial Intelligence (AI) and in related areas of advanced computing, provide us with a unique opportunity to push beyond the present level of computer aided automation technology and to attain substantial advances in the understanding and mechanization of design processes. To attain these goals, we need to build on top of the present state of AI, and to accelerate research and development in areas that are especially relevant to design problems of realistic complexity. We propose an approach to the special challenges in this area, which combines 'core work' in AI with the development of systems for handling significant design tasks. We discuss the general nature of design problems, the scientific issues involved in studying them with the help of AI approaches, and the methodological/technical issues that one must face in developing AI systems for handling advanced design tasks. Looking at basic work in AI from the perspective of design automation, we identify a number of research problems that need special attention. These include finding solution methods for handling multiple interacting goals, formation problems, problem decompositions, and redesign problems; choosing representations for design problems with emphasis on the concept of a design record; and developing approaches for the acquisition and structuring of domain knowledge with emphasis on finding useful approximations to domain theories. Progress in handling these research problems will have major impact both on our understanding of design processes and their automation, and also on several fundamental questions

  4. Field variability and vulnerability index to identify precision agriculture opportunity

    USDA-ARS?s Scientific Manuscript database

    Innovations in precision agriculture (PA) have created opportunities to achieve a greater understanding of within-field variability. However, PA adoption has been hindered due to uncertainty about field-specific performance and return on investment. Uncertainty could be better addressed by analyzing...

  5. Hydrological connectivity for riverine fish: measurement challenges and research opportunities

    USGS Publications Warehouse

    Fullerton, A.H.; Burnett, K.M.; Steel, E.A.; Flitcroft, R.L.; Pess, G.R.; Feist, B.E.; Torgersen, Christian E.; Miller, D.J.; Sanderson, B.L.

    2010-01-01

    In this review, we first summarize how hydrologic connectivity has been studied for riverine fish capable of moving long distances, and then identify research opportunities that have clear conservation significance. Migratory species, such as anadromous salmonids, are good model organisms for understanding ecological connectivity in rivers because the spatial scale over which movements occur among freshwater habitats is large enough to be easily observed with available techniques; they are often economically or culturally valuable with habitats that can be easily fragmented by human activities; and they integrate landscape conditions from multiple surrounding catchment(s) with in‐river conditions. Studies have focussed on three themes: (i) relatively stable connections (connections controlled by processes that act over broad spatio‐temporal scales >1000 km2 and >100 years); (ii) dynamic connections (connections controlled by processes acting over fine to moderate spatio‐temporal scales ∼1–1000 km2 and <1–100 years); and (iii) anthropogenic influences on hydrologic connectivity, including actions that disrupt or enhance natural connections experienced by fish.We outline eight challenges to understanding the role of connectivity in riverine fish ecology, organized under three foci: (i) addressing the constraints of river structure; (ii) embracing temporal complexity in hydrologic connectivity; and (iii) managing connectivity for riverine fishes. Challenges include the spatial structure of stream networks, the force and direction of flow, scale‐dependence of connectivity, shifting boundaries, complexity of behaviour and life histories and quantifying anthropogenic influence on connectivity and aligning management goals. As we discuss each challenge, we summarize relevant approaches in the literature and provide additional suggestions for improving research and management of connectivity for riverine fishes.Specifically, we suggest that rapid

  6. Myths, Artifacts, and Fatal Flaws: Identifying Limitations and Opportunities in Vitamin C Research

    PubMed Central

    Michels, Alexander J.; Frei, Balz

    2013-01-01

    Research progress to understand the role of vitamin C (ascorbic acid) in human health has been slow in coming. This is predominantly the result of several flawed approaches to study design, often lacking a full appreciation of the redox chemistry and biology of ascorbic acid. In this review, we summarize our knowledge surrounding the limitations of common approaches used in vitamin C research. In human cell culture, the primary issues are the high oxygen environment, presence of redox-active transition metal ions in culture media, and the use of immortalized cell lines grown in the absence of supplemental ascorbic acid. Studies in animal models are also limited due to the presence of endogenous ascorbic acid synthesis. Despite the use of genetically altered rodent strains lacking synthesis capacity, there are additional concerns that these models do not adequately recapitulate the effects of vitamin C deprivation and supplementation observed in humans. Lastly, several flaws in study design endemic to randomized controlled trials and other human studies greatly limit their conclusions and impact. There also is anecdotal evidence of positive and negative health effects of vitamin C that are widely accepted but have not been substantiated. Only with careful attention to study design and experimental detail can we further our understanding of the possible roles of vitamin C in promoting human health and preventing or treating disease. PMID:24352093

  7. Improving Science and IT Literacy by Providing Urban-Based Environmental Science Research Opportunities

    NASA Astrophysics Data System (ADS)

    Cuff, K. E.; Corazza, L.; Liang, J.

    2007-12-01

    A U.C. Berkeley-based outreach program known as Environmental Science Information Technology Activities has been in operation over the past four years. The primary aim of the program is to provide opportunities for grades 9 and 10 students in diverse East San Francisco Bay Area communities to develop deeper understandings of the nature and conduct of science, which will increase their capacity to enroll and perform successfully in science, technology, engineering, and mathematics (STEM) courses in the future. Design of the program has been informed by recent research that indicates a close relationship between educational activities that promote the perception of STEM as being relevant and the ability to foster development of deeper conceptual understandings among teens. Accordingly, ESITA includes an important student-led environmental science research project component, which provides participants with opportunities to engage in research investigations that are directly linked to relevant, real-world environmental problems and issues facing their communities. Analysis of evidence gleaned from questionnaires, interviews with participants and specific assessment/evaluation instruments indicates that ESITA program activities, including after-school meetings, summer and school year research projects, and conference preparations and presentations has provided students with high-quality inquiry science experiences that increased their knowledge of STEM and IT concepts, as well as their understanding of the nature of the scientific enterprise. In addition, the program has achieved a high degree of success in that it has: enhanced participants' intellectual self-confidence with regard to STEM; developed deeper appreciation of how scientific research can contribute to the maintenance of healthy local environments; developed a greater interest in participating in STEM-related courses of study and after school programs; and improved attitudes toward STEM. Overall

  8. Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge

    PubMed Central

    Miller, Mark R.; Clift, Martin J.D.; Elder, Alison; Mills, Nicholas L.; Møller, Peter; Schins, Roel P.F.; Vogel, Ulla; Kreyling, Wolfgang G.; Alstrup Jensen, Keld; Kuhlbusch, Thomas A.J.; Schwarze, Per E.; Hoet, Peter; Pietroiusti, Antonio; De Vizcaya-Ruiz, Andrea; Baeza-Squiban, Armelle; Teixeira, João Paulo; Tran, C. Lang; Cassee, Flemming R.

    2017-01-01

    Background: A rich body of literature exists that has demonstrated adverse human health effects following exposure to ambient air particulate matter (PM), and there is strong support for an important role of ultrafine (nanosized) particles. At present, relatively few human health or epidemiology data exist for engineered nanomaterials (NMs) despite clear parallels in their physicochemical properties and biological actions in in vitro models. Objectives: NMs are available with a range of physicochemical characteristics, which allows a more systematic toxicological analysis. Therefore, the study of ultrafine particles (UFP, <100 nm in diameter) provides an opportunity to identify plausible health effects for NMs, and the study of NMs provides an opportunity to facilitate the understanding of the mechanism of toxicity of UFP. Methods: A workshop of experts systematically analyzed the available information and identified 19 key lessons that can facilitate knowledge exchange between these discipline areas. Discussion: Key lessons range from the availability of specific techniques and standard protocols for physicochemical characterization and toxicology assessment to understanding and defining dose and the molecular mechanisms of toxicity. This review identifies a number of key areas in which additional research prioritization would facilitate both research fields simultaneously. Conclusion: There is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424 PMID:29017987

  9. Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge.

    PubMed

    Stone, Vicki; Miller, Mark R; Clift, Martin J D; Elder, Alison; Mills, Nicholas L; Møller, Peter; Schins, Roel P F; Vogel, Ulla; Kreyling, Wolfgang G; Alstrup Jensen, Keld; Kuhlbusch, Thomas A J; Schwarze, Per E; Hoet, Peter; Pietroiusti, Antonio; De Vizcaya-Ruiz, Andrea; Baeza-Squiban, Armelle; Teixeira, João Paulo; Tran, C Lang; Cassee, Flemming R

    2017-10-10

    A rich body of literature exists that has demonstrated adverse human health effects following exposure to ambient air particulate matter (PM), and there is strong support for an important role of ultrafine (nanosized) particles. At present, relatively few human health or epidemiology data exist for engineered nanomaterials (NMs) despite clear parallels in their physicochemical properties and biological actions in in vitro models. NMs are available with a range of physicochemical characteristics, which allows a more systematic toxicological analysis. Therefore, the study of ultrafine particles (UFP, <100 nm in diameter) provides an opportunity to identify plausible health effects for NMs, and the study of NMs provides an opportunity to facilitate the understanding of the mechanism of toxicity of UFP. A workshop of experts systematically analyzed the available information and identified 19 key lessons that can facilitate knowledge exchange between these discipline areas. Key lessons range from the availability of specific techniques and standard protocols for physicochemical characterization and toxicology assessment to understanding and defining dose and the molecular mechanisms of toxicity. This review identifies a number of key areas in which additional research prioritization would facilitate both research fields simultaneously. There is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424.

  10. [Opportunity for the integration of the gender perspective in health research and innovation in Europe: COST Network genderSTE].

    PubMed

    Sánchez de Madariaga, Inés; Ruiz Cantero, María Teresa

    2014-01-01

    The European Commission supports several routes for incorporating the gender perspective. The Commission currently supports the new Horizon 2020 program, and also funds projects such as "gendered innovations", which show how gender innovations increase the quality of research and professional practice for health and welfare. One of the policy instruments is the Recommendation on Gender, Science and Innovation. Against this background, the international European Cooperation in Science and Technology (COST) network genderSTE (Gender, Science, Technology and Environment) was created, which seeks to: 1) promote structural changes in institutions to increase the number of women researchers; 2) identify the gender dimensions relevant to the environment; and 3) improve the integration of a gender perspective in research and technology. COST GenderSTE supports networking and the dissemination of knowledge with a gender perspective. All these tools provide an opportunity to incorporate a gender perspective in research in Europe. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  11. Aerobic Excercise and Research Opportunities to Benefit Impaired Children. (Project AEROBIC). Final Report.

    ERIC Educational Resources Information Center

    Idaho Univ., Moscow.

    The final report summarizes accomplishments of Project AEROBIC (Aerobic Exercise and Research Opportunities to Benefit Impaired Children), which provided a physical education exercise program for severely, profoundly, and multiply handicapped children aged 10-21. Activities are outlined for the 3 year period and include modification of exercise…

  12. From Nonclinical Research to Clinical Trials and Patient-registries: Challenges and Opportunities in Biomedical Research

    PubMed Central

    de la Torre Hernández, José M.; Edelman, Elazer R.

    2018-01-01

    The most important challenge faced by human beings is health. The only way to provide better solutions for health care is innovation, true innovation. The only source of true innovation is research, good research indeed. The pathway from a basic science study to a randomized clinical trial is long and not free of bumps and even landmines. These are all the obstacles and barriers that limit the availability of resources, entangle administrative-regulatory processes, and restrain investigators’ initiatives. There is increasing demand for evidence to guide clinical practice but, paradoxically, biomedical research has become increasingly complex, expensive, and difficult to integrate into clinical care with increased barriers to performing the practical aspects of investigation. We face the challenge of increasing the volume of biomedical research and simultaneously improving the efficiency and output of this research. In this article, we review the main stages and methods of biomedical research, from nonclinical studies with animal and computational models to randomized trials and clinical registries, focusing on their limitations and challenges, but also providing alternative solutions to overcome them. Fortunately, challenges are always opportunities in disguise. PMID:28838647

  13. Research opportunities in interdisciplinary ground-water science in the U.S. Geological Survey

    USGS Publications Warehouse

    Sanford, W.E.; Caine, Jonathan S.; Wilcox, D.A.; McWreath, H.C.; Nicholas, J.R.

    2006-01-01

    This report is written for the scientifically literate reader but is not limited to those who are involved in ground-water science. The report is intended to encourage U.S. Geological Survey scientists to develop a sense of excitement about ground-water science in the agency, to inform scientists about existing and potential ground-water science opportunities, and to engage scientists and managers in interdisciplinary discussions and collaboration. The report is intended for use by U.S. Geological Survey and Department of the Interior management to formulate long-term ground-water science programs and to continue sustained support of ground-water monitoring and research, some of which may not have an immediate impact. Finally, the report can be used to communicate the U.S. Geological Survey's vision of ground-water science to Congress, partners, other agencies, and the research community at large with the goals of enhancing collaborative opportunities, sharing information, and maintaining dialogue regarding the directions of U.S. Geological Survey ground-water science.

  14. Multiscale Computation. Needs and Opportunities for BER Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scheibe, Timothy D.; Smith, Jeremy C.

    2015-01-01

    The Environmental Molecular Sciences Laboratory (EMSL), a scientific user facility managed by Pacific Northwest National Laboratory for the U.S. Department of Energy, Office of Biological and Environmental Research (BER), conducted a one-day workshop on August 26, 2014 on the topic of “Multiscale Computation: Needs and Opportunities for BER Science.” Twenty invited participants, from various computational disciplines within the BER program research areas, were charged with the following objectives; Identify BER-relevant models and their potential cross-scale linkages that could be exploited to better connect molecular-scale research to BER research at larger scales and; Identify critical science directions that will motivate EMSLmore » decisions regarding future computational (hardware and software) architectures.« less

  15. An implementation science perspective on psychological science and cancer: what is known and opportunities for research, policy, and practice.

    PubMed

    Rabin, Borsika; Glasgow, Russell E

    2015-01-01

    We discuss the role of implementation science in cancer and summarize the need for this perspective. Following a summary of key implementation science principles and lessons learned, we review the literature on implementation of cancer prevention and control activities across the continuum from prevention to palliative care. We identified 10 unique relevant reviews, four of which were specific to cancer. Multicomponent implementation strategies were found to be superior to single-component interventions, but it was not possible to draw conclusions about specific strategies or the range of conditions across which strategies were effective. Particular gaps identified include the need for more studies of health policies and reports of cost, cost-effectiveness, and resources required. Following this review, we summarize the types of evidence needed to make research findings more actionable and discuss emerging implementation science opportunities for psychological research on cancer prevention and control. These include innovative study designs (i.e., rapid learning designs, simulation modeling, comparative effectiveness, pragmatic studies, mixed-methods research) and measurement science (i.e., development of context-relevant measures; practical, longitudinal measures to gauge improvement; cost-effectiveness data; and harmonized patient report data). We conclude by identifying a few grand challenges for psychologists that if successfully addressed would accelerate integration of evidence into cancer practice and policy more consistently and rapidly. PsycINFO Database Record (c) 2015 APA, all rights reserved.

  16. Challenges and Opportunities in Interdisciplinary Materials Research Experiences for Undergraduates

    NASA Astrophysics Data System (ADS)

    Vohra, Yogesh; Nordlund, Thomas

    2009-03-01

    The University of Alabama at Birmingham (UAB) offer a broad range of interdisciplinary materials research experiences to undergraduate students with diverse backgrounds in physics, chemistry, applied mathematics, and engineering. The research projects offered cover a broad range of topics including high pressure physics, microelectronic materials, nano-materials, laser materials, bioceramics and biopolymers, cell-biomaterials interactions, planetary materials, and computer simulation of materials. The students welcome the opportunity to work with an interdisciplinary team of basic science, engineering, and biomedical faculty but the challenge is in learning the key vocabulary for interdisciplinary collaborations, experimental tools, and working in an independent capacity. The career development workshops dealing with the graduate school application process and the entrepreneurial business activities were found to be most effective. The interdisciplinary university wide poster session helped student broaden their horizons in research careers. The synergy of the REU program with other concurrently running high school summer programs on UAB campus will also be discussed.

  17. Consanguinity in Saudi Arabia: a unique opportunity for pediatric kidney research.

    PubMed

    Kari, Jameela A; Bockenhauer, Detlef; Stanescu, Horia; Gari, Mamdooh; Kleta, Robert; Singh, Ajay K

    2014-02-01

    Identification of disease-related genes is a critical step in understanding the molecular basis of disease and developing targeted therapies. The genetic study of diseases occurring in the offspring of consanguineous unions is a powerful way to discover new disease genes. Pediatric nephrology provides an excellent example because ∼70% of cases of kidney disease in childhood are congenital with a likely genetic basis. This percentage is likely to be even higher in countries with a high consanguinity rate, such as the Kingdom of Saudi Arabia. However, there are a number of challenges, such as cultural, legal, and religious restrictions, that should be appreciated before carrying out genetic research in a tradition-bound country. In this article, we discuss the background, opportunities, and challenges involved with this unique opportunity to conduct studies of such genetic disorders. Keys to success include collaboration and an understanding of local traditions and laws. Copyright © 2014 National Kidney Foundation, Inc. All rights reserved.

  18. Financing prevention: opportunities for economic analysis across the translational research cycle.

    PubMed

    Crowley, D Max; Jones, Damon

    2016-03-01

    Prevention advocates often make the case that preventive intervention not only improves public health and welfare but also can save public resources. Increasingly, evidence-based policy efforts considering prevention are focusing on how programs can save taxpayer resources from reduced burden on health, criminal justice, and social service systems. Evidence of prevention's return has begun to draw substantial investments from the public and private sector. Yet, translating prevention effectiveness into economic impact requires specific economic analyses to be employed across the stages of translational research. This work discusses the role of economic analysis in prevention science and presents key translational research opportunities to meet growing demand for estimates of prevention's economic and fiscal impact.

  19. Identifying Invasive Species Educational Needs in Florida: Opportunities for Extension

    ERIC Educational Resources Information Center

    Huang, Pei-wen; Lamm, Alexa J.

    2016-01-01

    Florida's ecology has been adversely affected by invasive species. In Florida, a study was conducted to explore opportunities for Extension educators to contribute to combating the issue of invasive species. Florida residents' responses were captured through the use of an online public opinion survey. The findings revealed a need for invasive…

  20. The python project: a unique model for extending research opportunities to undergraduate students.

    PubMed

    Harvey, Pamela A; Wall, Christopher; Luckey, Stephen W; Langer, Stephen; Leinwand, Leslie A

    2014-01-01

    Undergraduate science education curricula are traditionally composed of didactic instruction with a small number of laboratory courses that provide introductory training in research techniques. Research on learning methodologies suggests this model is relatively ineffective, whereas participation in independent research projects promotes enhanced knowledge acquisition and improves retention of students in science. However, availability of faculty mentors and limited departmental budgets prevent the majority of students from participating in research. A need therefore exists for this important component in undergraduate education in both small and large university settings. A course was designed to provide students with the opportunity to engage in a research project in a classroom setting. Importantly, the course collaborates with a sponsor's laboratory, producing a symbiotic relationship between the classroom and the laboratory and an evolving course curriculum. Students conduct a novel gene expression study, with their collective data being relevant to the ongoing research project in the sponsor's lab. The success of this course was assessed based on the quality of the data produced by the students, student perception data, student learning gains, and on whether the course promoted interest in and preparation for careers in science. In this paper, we describe the strategies and outcomes of this course, which represents a model for efficiently providing research opportunities to undergraduates. © 2014 P. A. Harvey et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  1. Opportunities for Undergraduate Research in Nuclear Physics

    DOE PAGES

    Hicks, S. F.; Nguyen, T. D.; Jackson, D. T.; ...

    2017-10-26

    University of Dallas (UD) physics majors are offered a variety of undergraduate research opportunities in nuclear physics through an established program at the University of Kentucky Accelerator Laboratory (UKAL). The 7-MV Model CN Van de Graaff accelerator and the neutron production and detection facilities located there are used by UD students to investigate how neutrons scatter from materials that are important in nuclear energy production and for our basic understanding of how neutrons interact with matter. Recent student projects include modeling of the laboratory using the neutron transport code MCNP to investigate the effectiveness of laboratory shielding, testing the long-termmore » gain stability of C 6D 6 liquid scintillation detectors, and deducing neutron elastic and inelastic scattering cross sections for 12C. Finally, results of these student projects are presented that indicate the pit below the scattering area reduces background by as much as 30%; the detectors show no significant gain instabilities; and new insights into existing 12C neutron inelastic scattering cross-section discrepancies near a neutron energy of 6.0 MeV are obtained.« less

  2. Opportunities for Undergraduate Research in Nuclear Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hicks, S. F.; Nguyen, T. D.; Jackson, D. T.

    University of Dallas (UD) physics majors are offered a variety of undergraduate research opportunities in nuclear physics through an established program at the University of Kentucky Accelerator Laboratory (UKAL). The 7-MV Model CN Van de Graaff accelerator and the neutron production and detection facilities located there are used by UD students to investigate how neutrons scatter from materials that are important in nuclear energy production and for our basic understanding of how neutrons interact with matter. Recent student projects include modeling of the laboratory using the neutron transport code MCNP to investigate the effectiveness of laboratory shielding, testing the long-termmore » gain stability of C 6D 6 liquid scintillation detectors, and deducing neutron elastic and inelastic scattering cross sections for 12C. Finally, results of these student projects are presented that indicate the pit below the scattering area reduces background by as much as 30%; the detectors show no significant gain instabilities; and new insights into existing 12C neutron inelastic scattering cross-section discrepancies near a neutron energy of 6.0 MeV are obtained.« less

  3. Evaluation of Minority Retention Programs: The Undergraduate Research Opportunities Program at the University of Michigan.

    ERIC Educational Resources Information Center

    Jonides, John; And Others

    An evaluation was done of the first year of the Undergraduate Research Opportunities Program (UROP) at the University of Michigan (Ann Arbor), which is designed not only to teach students about research and/or certain academic topics, but also to facilitate the identification of minority students with the university. This second aim is based on…

  4. WASTE OPPORTUNITY ASSESSMENT: A PHOTOFINISHING FACILITY

    EPA Science Inventory

    A waste minimization opportunity assessment was performed which identified areas for waste reduction at a photofinishing facility. The study followed procedures in the EPA Waste Minimization Opportunity Assessment Manual. The report identifies potential options to achieve further...

  5. Views of potential research participants on financial conflicts of interest: barriers and opportunities for effective disclosure.

    PubMed

    Weinfurt, Kevin P; Friedman, Joëlle Y; Allsbrook, Jennifer S; Dinan, Michaela A; Hall, Mark A; Sugarman, Jeremy

    2006-09-01

    There is little guidance regarding how to disclose researchers' financial interests to potential research participants. To determine what potential research participants want to know about financial interests, their capacity to understand disclosed information and its implications, and the reactions of potential research participants to a proposed disclosure statement. Sixteen focus groups in 3 cities, including 6 groups of healthy adults, 6 groups of adults with mild chronic illness, 1 group of parents of healthy children, 1 group of parents of children with leukemia or brain tumor, 1 group of adults with heart failure, and 1 group of adults with cancer. Focus group discussions covered a range of topics including financial relationships in clinical research, whether people should be told about them, and how they should be told. Audio-recordings of focus groups were transcribed, verified, and coded for analysis. Participants wanted to know about financial interests, whether or not those interests would affect their participation. However, they varied in their desire and ability to understand the nature and implications of financial interests. Whether disclosure was deemed important depended upon the risk of the research. Trust in clinicians was also related to views regarding disclosure. If given the opportunity to ask questions during the consent process, some participants would not have known what to ask; however, after the focus group sessions, participants could identify information they would want to know. Financial interests are important to potential research participants, but obstacles to effective disclosure exist.

  6. Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia.

    PubMed

    de Jong, Simone; Vidler, Lewis R; Mokrab, Younes; Collier, David A; Breen, Gerome

    2016-08-01

    Genome-wide association studies (GWAS) have identified thousands of novel genetic associations for complex genetic disorders, leading to the identification of potential pharmacological targets for novel drug development. In schizophrenia, 108 conservatively defined loci that meet genome-wide significance have been identified and hundreds of additional sub-threshold associations harbour information on the genetic aetiology of the disorder. In the present study, we used gene-set analysis based on the known binding targets of chemical compounds to identify the 'drug pathways' most strongly associated with schizophrenia-associated genes, with the aim of identifying potential drug repositioning opportunities and clues for novel treatment paradigms, especially in multi-target drug development. We compiled 9389 gene sets (2496 with unique gene content) and interrogated gene-based p-values from the PGC2-SCZ analysis. Although no single drug exceeded experiment wide significance (corrected p<0.05), highly ranked gene-sets reaching suggestive significance including the dopamine receptor antagonists metoclopramide and trifluoperazine and the tyrosine kinase inhibitor neratinib. This is a proof of principle analysis showing the potential utility of GWAS data of schizophrenia for the direct identification of candidate drugs and molecules that show polypharmacy. © The Author(s) 2016.

  7. Research Opportunities in Space Propulsion

    NASA Technical Reports Server (NTRS)

    Rodgers, Stephen L.

    2007-01-01

    Rocket propulsion determines the primary characteristics of any space vehicle; how fast and far it can go, its lifetime, and its capabilities. It is the primary factor in safety and reliability and the biggest cost driver. The extremes of heat and pressure produced by propulsion systems push the limits of materials used for manufacturing. Space travel is very unforgiving with little room for errors, and so many things can go wrong with these very complex systems. So we have to plan for failure and that makes it costly. But what is more exciting than the roar of a rocket blasting into space? By its nature the propulsion world is conservative. The stakes are so high at every launch, in terms of payload value or in human life, that to introduce new components to a working, qualified system is extremely difficult and costly. Every launch counts and no risks are tolerated, which leads to the space world's version of Catch-22:"You can't fly till you flown." The last big 'game changer' in propulsion was the use of liquid hydrogen as a fuel. No new breakthrough, low cost access to space system will be developed without new efficient propulsion systems. Because there is no large commercial market driving investment in propulsion, what propulsion research is done is sponsored by government funding agencies. A further difficulty in propulsion technology development is that there are so few new systems flying. There is little opportunity to evolve propulsion technologies and to update existing systems with results coming out of research as there is in, for example, the auto industry. The biggest hurdle to space exploration is getting off the ground. The launch phase will consume most of the energy required for any foreseeable space exploration mission. The fundamental physical energy requirements of escaping earth's gravity make it difficult. It takes 60,000 kJ to put a kilogram into an escape orbit. The vast majority (-97%) of the energy produced by a launch vehicle is used

  8. Identifying research priorities for public health research to address health inequalities: use of Delphi-like survey methods.

    PubMed

    Turner, S; Ollerhead, E; Cook, A

    2017-10-09

    In the funding of health research and public health research it is vital that research questions posed are important and that funded research meets a research need or a gap in evidence. Many methods are used in the identification of research priorities, however, these can be resource intensive, costly and logistically challenging. Identifying such research priorities can be particularly challenging for complex public health problems as there is a need to consult a number of experts across disciplines and with a range of expertise. This study investigated the use of Delphi-like survey methods in identifying important research priorities relating to health inequalities and framing tractable research questions for topic areas identified. The study was conducted in two phases, both using Delphi-like survey methods. Firstly, public health professionals with an interest in health inequalities were asked to identify research priorities. Secondly academic researchers were asked to frame tractable research questions relating to the priorities identified. These research priorities identified using Delphi-like survey methods were subsequently compared to those identified using different methods. A total of 52 public health professionals and 21 academics across the United Kingdom agreed to take part. The response rates were high, from public health professionals across three survey rounds (69%, 50% and 40%) and from academics across one round (52%), indicating that participants were receptive to the method and motivated to respond. The themes identified as encompassing the most important research priorities were mental health, healthy environment and health behaviours. Within these themes, the topic areas that emerged most strongly included community interventions for prevention of mental health problems and the food and alcohol environment. Some responses received from academic researchers were (as requested) in the form of tractable research questions, whereas others

  9. Opportunities and insights for reducing fossil fuel consumption by households and organizations

    NASA Astrophysics Data System (ADS)

    Stern, Paul C.; Janda, Kathryn B.; Brown, Marilyn A.; Steg, Linda; Vine, Edward L.; Lutzenhiser, Loren

    2016-05-01

    Realizing the ambitious commitments of the 2015 Paris Climate Conference (COP21) will require new ways of meeting human needs previously met by burning fossil fuels. Technological developments will be critical, but so will accelerated adoption of promising low-emission technologies and practices. National commitments will be more achievable if interventions take into account key psychological, social, cultural and organizational factors that influence energy choices, along with factors of an infrastructural, technical and economic nature. Broader engagement of social and behavioural science is needed to identify promising opportunities for reducing fossil fuel consumption. Here we discuss opportunities for change in households and organizations, primarily at short and intermediate timescales, and identify opportunities that have been underused in much of energy policy. Based on this survey, we suggest design principles for interventions by governments and other organizations, and identify areas of emphasis for future social science and interdisciplinary research.

  10. Academic research opportunities at the National Geospatial-Intelligence Agency(NGA)

    NASA Astrophysics Data System (ADS)

    Loomer, Scott A.

    2006-05-01

    The vision of the National Geospatial-Intelligence Agency (NGA) is to "Know the Earth...Show the Way." To achieve this vision, the NGA provides geospatial intelligence in all its forms and from whatever source-imagery, imagery intelligence, and geospatial data and information-to ensure the knowledge foundation for planning, decision, and action. Academia plays a key role in the NGA research and development program through the NGA Academic Research Program. This multi-disciplinary program of basic research in geospatial intelligence topics provides grants and fellowships to the leading investigators, research universities, and colleges of the nation. This research provides the fundamental science support to NGA's applied and advanced research programs. The major components of the NGA Academic Research Program are: *NGA University Research Initiatives (NURI): Three-year basic research grants awarded competitively to the best investigators across the US academic community. Topics are selected to provide the scientific basis for advanced and applied research in NGA core disciplines. *Historically Black College and University - Minority Institution Research Initiatives (HBCU-MI): Two-year basic research grants awarded competitively to the best investigators at Historically Black Colleges and Universities, and Minority Institutions across the US academic community. *Intelligence Community Post-Doctoral Research Fellowships: Fellowships providing access to advanced research in science and technology applicable to the intelligence community's mission. The program provides a pool of researchers to support future intelligence community needs and develops long-term relationships with researchers as they move into career positions. This paper provides information about the NGA Academic Research Program, the projects it supports and how researchers and institutions can apply for grants under the program. In addition, other opportunities for academia to engage with NGA through

  11. Ethics and Regulatory Challenges and Opportunities in Patient-Centered Comparative Effectiveness Research.

    PubMed

    Sugarman, Jeremy

    2016-04-01

    The Affordable Care Act includes provisions for the conduct of large-scale, patient-centered comparative effectiveness research. Such efforts aim toward the laudable moral goal of having evidence to improve health care decision making. Nevertheless, these pragmatic clinical research efforts that typically pose minimal incremental risk and are enmeshed in routine care settings perhaps surprisingly encounter an array of ethics and regulatory challenges and opportunities for academic health centers. An emphasis on patient-centeredness forces an examination of the appropriateness of traditional methods used to protect the rights, interests, and welfare of participants. At the same time, meaningful collaboration with patients throughout the research process also necessitates ensuring that novel approaches to research (including recruitment and consent) entail necessary protections regarding such issues as privacy. As the scientific and logistical aspects of this research are being developed, substantial attention is being focused on the accompanying ethics and regulatory issues that have emerged, which should help to facilitate ethically appropriate research in a variety of contexts.

  12. Lessons Learned in Developing Research Opportunities for Native American Undergraduate Students: The GEMscholars Project

    NASA Astrophysics Data System (ADS)

    Zurn-Birkhimer, S. M.; Filley, T. R.; Kroeger, T. J.

    2008-12-01

    Interventions for the well-documented national deficiency of underrepresented students in higher education have focused primarily on the undergraduate student population with significantly less attention given to issues of diversity within graduate programs. As a result, we have made little progress in transforming faculty composition to better reflect the nation's diversity resulting in relatively few minority mentors joining faculty ranks and schools falling short of the broader representation to create an enriched, diverse academic environment. The GEMscholars (Geology, Environmental Science and Meteorology scholars) Program began in the summer of 2006 with the goal of increasing the number of Native American students pursuing graduate degrees in the geosciences. We drew on research from Native American student education models to address three key themes of (a) mentoring, (b) culturally relevant valuations of geosciences and possible career paths, and (c) connections to community and family. A collaboration between Purdue University, West Lafayette, IN and three institutions in northern Minnesota; Bemidji State University, Red Lake Nation College and Leech Lake Tribal College, is structured to develop research opportunities and a support network for Native American undergraduate students (called GEMscholars) to participate in summer geoscience research projects in their home communities. Research opportunities were specifically chosen to have cultural relevance and yield locally important findings. The GEMscholars work on projects that directly link to their local ecosystems and permit them to engage in long term monitoring and cohesive interaction among each successive year's participants. For example, the GEMscholars have established and now maintain permanent field monitoring plots to assess the impacts of invasive European earthworm activity on forest ecosystem health. The culmination of the summer project is the GEMscholars Symposium at Purdue University

  13. Opportunities and Challenges for Personal Heat Exposure Research

    PubMed Central

    Kuras, Evan R.; Richardson, Molly B.; Calkins, Miriam M.; Ebi, Kristie L.; Hess, Jeremy J.; Kintziger, Kristina W.; Jagger, Meredith A.; Middel, Ariane; Scott, Anna A.; Spector, June T.; Uejio, Christopher K.; Vanos, Jennifer K.; Zaitchik, Benjamin F.; Gohlke, Julia M.

    2017-01-01

    Background: Environmental heat exposure is a public health concern. The impacts of environmental heat on mortality and morbidity at the population scale are well documented, but little is known about specific exposures that individuals experience. Objectives: The first objective of this work was to catalyze discussion of the role of personal heat exposure information in research and risk assessment. The second objective was to provide guidance regarding the operationalization of personal heat exposure research methods. Discussion: We define personal heat exposure as realized contact between a person and an indoor or outdoor environment that poses a risk of increases in body core temperature and/or perceived discomfort. Personal heat exposure can be measured directly with wearable monitors or estimated indirectly through the combination of time–activity and meteorological data sets. Complementary information to understand individual-scale drivers of behavior, susceptibility, and health and comfort outcomes can be collected from additional monitors, surveys, interviews, ethnographic approaches, and additional social and health data sets. Personal exposure research can help reveal the extent of exposure misclassification that occurs when individual exposure to heat is estimated using ambient temperature measured at fixed sites and can provide insights for epidemiological risk assessment concerning extreme heat. Conclusions: Personal heat exposure research provides more valid and precise insights into how often people encounter heat conditions and when, where, to whom, and why these encounters occur. Published literature on personal heat exposure is limited to date, but existing studies point to opportunities to inform public health practice regarding extreme heat, particularly where fine-scale precision is needed to reduce health consequences of heat exposure. https://doi.org/10.1289/EHP556 PMID:28796630

  14. 78 FR 42532 - Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... DEPARTMENT OF HOMELAND SECURITY Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of Homeland Security for the Development of a Foot-and-Mouth Disease 3ABC ELISA... in developing and validating an ELISA diagnostic kit for detection of Foot and Mouth Disease Virus...

  15. Research opportunities with compact accelerator-driven neutron sources

    NASA Astrophysics Data System (ADS)

    Anderson, I. S.; Andreani, C.; Carpenter, J. M.; Festa, G.; Gorini, G.; Loong, C.-K.; Senesi, R.

    2016-10-01

    Since the discovery of the neutron in 1932 neutron beams have been used in a very broad range of applications, As an aging fleet of nuclear reactor sources is retired the use of compact accelerator-driven neutron sources (CANS) is becoming more prevalent. CANS are playing a significant and expanding role in research and development in science and engineering, as well as in education and training. In the realm of multidisciplinary applications, CANS offer opportunities over a wide range of technical utilization, from interrogation of civil structures to medical therapy to cultural heritage study. This paper aims to provide the first comprehensive overview of the history, current status of operation, and ongoing development of CANS worldwide. The basic physics and engineering regarding neutron production by accelerators, target-moderator systems, and beam line instrumentation are introduced, followed by an extensive discussion of various evolving applications currently exploited at CANS.

  16. Evolutionary ethnobiology and cultural evolution: opportunities for research and dialog.

    PubMed

    Santoro, Flávia Rosa; Nascimento, André Luiz Borba; Soldati, Gustavo Taboada; Ferreira Júnior, Washington Soares; Albuquerque, Ulysses Paulino

    2018-01-09

    The interest in theoretical frameworks that improve our understanding of social-ecological systems is growing within the field of ethnobiology. Several evolutionary questions may underlie the relationships between people and the natural resources that are investigated in this field. A new branch of research, known as evolutionary ethnobiology (EE), focuses on these questions and has recently been formally conceptualized. The field of cultural evolution (CE) has significantly contributed to the development of this new field, and it has introduced the Darwinian concepts of variation, competition, and heredity to studies that focus on the dynamics of local knowledge. In this article, we introduce CE as an important theoretical framework for evolutionary ethnobiological research. We present the basic concepts and assumptions of CE, along with the adjustments that are necessary for its application in EE. We discuss different ethnobiological studies in the context of this new framework and the new opportunities for research that exist in this area. We also propose a dialog that includes our findings in the context of cultural evolution.

  17. Commercial Research and Development: Power to Explore, Opportunities from Discovery

    NASA Technical Reports Server (NTRS)

    Casas, Joseph C.; Nall, Mark; Powers, C. Blake; Henderson, Robin N. (Technical Monitor)

    2002-01-01

    The technical and economic goals of commercial use of space are laudable, and are addressed as a high priority by almost every national space program and most major aerospace companies the world over. Yet, the focus of most organizational agendas and discussions tends to focus on one or two very narrow enabling aspects of this potentially large technological and economic opportunity. While government sponsored commercial launch activities and private space platforms are an integral part of efforts to leverage the commercial use of space, these activities are possibly one of the smallest parts of creating, a viable and sustainable market for the commercial use of space. Most of the current programs usually do not appropriately address some of the critical issues of the current, already interested, potential space user communities. Current programs place the focus of the majority of the user requirements on the vehicle payload weight and mass performance considerations as the primary payload economical factor in providing a commercial market with a stimulating price for gaining access to the space environment. The larger user challenges of transformation from Earth-based research and development approaches to space environment approaches are not addressed early enough in programs to impact the new business considerations of potential users. Currently, space-based research and development user activities require a large user investment in time, in development of new areas of support expertise, in development of new systems, in risk of schedule to completion, and in long term capital positioning. The larger opportunities for stimulating a strong market driven interest in commercial use of space that could result from the development of vehicle payload "leap ahead technologies" for users are being missed, and there is a real risk of limiting the potentially broader market base to support a more technologically advanced and economically lucrative outcome. A major driving

  18. Needs and Opportunities for Uncertainty-Based Multidisciplinary Design Methods for Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Zang, Thomas A.; Hemsch, Michael J.; Hilburger, Mark W.; Kenny, Sean P; Luckring, James M.; Maghami, Peiman; Padula, Sharon L.; Stroud, W. Jefferson

    2002-01-01

    This report consists of a survey of the state of the art in uncertainty-based design together with recommendations for a Base research activity in this area for the NASA Langley Research Center. This report identifies the needs and opportunities for computational and experimental methods that provide accurate, efficient solutions to nondeterministic multidisciplinary aerospace vehicle design problems. Barriers to the adoption of uncertainty-based design methods are identified. and the benefits of the use of such methods are explained. Particular research needs are listed.

  19. Research Opportunities Supporting the Vision for Space Exploration from the Transformation of the Former Microgravity Materials Science Program

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.; Szofran, Frank; Bassler, Julie A.; Schlagheck, Ronald A.; Cook, Mary Beth

    2005-01-01

    The Microgravity Materials Science Program established a strong research capability through partnerships between NASA and the scientific research community. With the announcement of the vision for space exploration, additional emphasis in strategic materials science areas was necessary. The President's Commission recognized that achieving its exploration objectives would require significant technical innovation, research, and development in focal areas defined as "enabling technologies." Among the 17 enabling technologies identified for initial focus were: advanced structures, advanced power and propulsion; closed-loop life support and habitability; extravehicular activity systems; autonomous systems and robotics; scientific data collection and analysis, biomedical risk mitigation; and planetary in situ resource utilization. Mission success may depend upon use of local resources to fabricate a replacement part to repair a critical system. Future propulsion systems will require materials with a wide range of mechanical, thermophysical, and thermochemical properties, many of them well beyond capabilities of today's materials systems. Materials challenges have also been identified by experts working to develop advanced life support systems. In responding to the vision for space exploration, the Microgravity Materials Science Program aggressively transformed its research portfolio and focused materials science areas of emphasis to include space radiation shielding; in situ fabrication and repair for life support systems; in situ resource utilization for life support consumables; and advanced materials for exploration, including materials science for space propulsion systems and for life support systems. The purpose of this paper is to inform the scientific community of these new research directions and opportunities to utilize their materials science expertise and capabilities to support the vision for space exploration.

  20. Gendered Opportunity? School-Based Adolescent Victimization

    ERIC Educational Resources Information Center

    Wilcox, Pamela; Tillyer, Marie Skubak; Fisher, Bonnie S.

    2009-01-01

    Researchers have shown that criminal opportunity significantly predicts school-based adolescent victimization. However, little is known about the extent to which opportunity for school-based victimization might be gendered. In this study, the authors drew from criminal opportunity and feminist research and extended the principle of homogamy to…

  1. Environmental Co-Benefit Opportunities of Solar Energy

    NASA Astrophysics Data System (ADS)

    Hernandez, R. R.; Armstrong, A.; Burney, J. A.; Easter, S. B.; Hoffacker, M. K.; Moore, K. A.

    2015-12-01

    Solar energy reduces greenhouse gas emissions by an order of magnitude when substituted for fossil fuels. Nonetheless, the strategic deployment of solar energy—from single, rooftop modules to utility-scale solar energy power plants—can confer additional environmental co-benefits beyond its immediate use as a low carbon energy source. In this study, we identify a diverse portfolio of environmental co-benefit opportunities of solar energy technologies resulting from synergistic innovations in land, food, energy, and water systems. For each opportunity, we provide a demonstrative, quantitative framework for environmental co-benefit valuation—including, equations, models, or case studies for estimating carbon dioxide equivalent (CO2-eq) and cost savings ($US) averted by environmental co-benefit opportunities of solar energy—and imminent research questions to improve certainty of valuations. As land-energy-food-water nexus issues are increasingly exigent in 21st century, we show that environmental co-benefit opportunities of solar energy are feasible in numerous environments and at a wide range of spatial scales thereby able to contribute to local and regional environmental goals and for the mitigation of climate change.

  2. [Big Data: the great opportunities and challenges to microbiome and other biomedical research].

    PubMed

    Xu, Zhenjiang

    2015-02-01

    With the development of high-throughput technologies, biomedical data has been increasing exponentially in an explosive manner. This brings enormous opportunities and challenges to biomedical researchers on how to effectively utilize big data. Big data is different from traditional data in many ways, described as 3Vs - volume, variety and velocity. From the perspective of biomedical research, here I introduced the characteristics of big data, such as its messiness, re-usage and openness. Focusing on microbiome research of meta-analysis, the author discussed the prospective principles in data collection, challenges of privacy protection in data management, and the scalable tools in data analysis with examples from real life.

  3. Opportunities and challenges of interdisciplinary research career development: implementation of a women's health research training program.

    PubMed

    Domino, Steven E; Smith, Yolanda R; Johnson, Timothy R B

    2007-03-01

    A key component of the National Institutes of Health (NIH) Roadmap for Medical Research is the development of interdisciplinary research teams. How best to teach and foster interdisciplinary research skills has not been determined. An effort at promoting interdisciplinary research was initiated by the Office of Research on Women's Health (ORWH) at NIH in 1999. The following year, 12 academic centers were funded to support 56 scholar positions for 2-5 years under Building Interdisciplinary Research Careers in Women's Health (BIRCWH). A second cohort of 12 centers, called BIRCWH II, was funded in 2002. In this paper, we present the experience of the University of Michigan BIRCWH program, including a practical approach to dealing with the challenges and opportunities of interdisciplinary research training. Scholars are mentored not only by their primary research advisor but also by a three-person mentor team as well as by their peers. All scholars and a core of supportive faculty meet regularly to discuss interdisciplinary research career development and approaches to apply knowledge in new ways. Of the original cohort of 10 scholars at the University of Michigan, 7 have achieved independent research funding. Challenges include arranging times to meet, developing a common language and knowledge base, dealing proactively with expectations and misunderstandings, focusing on a conceptual model, and providing timely feedback.

  4. The formal electronic recycling industry: Challenges and opportunities in occupational and environmental health research.

    PubMed

    Ceballos, Diana Maria; Dong, Zhao

    2016-10-01

    E-waste includes electrical and electronic equipment discarded as waste without intent of reuse. Informal e-waste recycling, typically done in smaller, unorganized businesses, can expose workers and communities to serious chemical health hazards. It is unclear if formalization into larger, better-controlled electronics recycling (e-recycling) facilities solves environmental and occupational health problems. To systematically review the literature on occupational and environmental health hazards of formal e-recycling facilities and discuss challenges and opportunities to strengthen research in this area. We identified 37 publications from 4 electronic databases (PubMed, Web of Science, Environmental Index, NIOSHTIC-2) specific to chemical exposures in formal e-recycling facilities. Environmental and occupational exposures depend on the degree of formalization of the facilities but further reduction is needed. Reported worker exposures to metals were often higher than recommended occupational guidelines. Levels of brominated flame-retardants in worker's inhaled air and biological samples were higher than those from reference groups. Air, dust, and soil concentrations of metals, brominated flame-retardants, dioxins, furans, polycyclic-aromatic hydrocarbons, or polychlorinated biphenyls found inside or near the facilities were generally higher than reference locations, suggesting transport into the environment. Children of a recycler had blood lead levels higher than public health recommended guidelines. With mounting e-waste, more workers, their family members, and communities could experience unhealthful exposures to metals and other chemicals. We identified research needs to further assess exposures, health, and improve controls. The long-term solution is manufacturing of electronics without harmful substances and easy-to-disassemble components. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Summary report of a workshop on research opportunities in plant biochemistry, December 11--13, 1992, Kona, Hawaii

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-31

    A DOE-sponsored workshop was held December 11--13, 1992 in Kona, Hawaii to discuss those aspects of fundamental research in plant biochemistry deemed essential to provide the basic information base necessary for exploiting plant biotechnology to meet future societal needs. Twenty nine scientists, with interests representing many of the various areas of plant biochemistry, participated. The workshop was intended to define in both broad and specific terms the current state of knowledge in the general area of metabolic biochemistry, and to identify those areas that afford unusual opportunity or that are relatively underdeveloped in comparison with other areas of plant biology.more » Participants provided critiques of the state of knowledge of the major areas of metabolic biochemistry in relation to a series of questions that are presented herein.« less

  6. Research Challenges and Opportunities for Clinically Oriented Academic Radiology Departments.

    PubMed

    Decker, Summer J; Grajo, Joseph R; Hazelton, Todd R; Hoang, Kimberly N; McDonald, Jennifer S; Otero, Hansel J; Patel, Midhir J; Prober, Allen S; Retrouvey, Michele; Rosenkrantz, Andrew B; Roth, Christopher G; Ward, Robert J

    2016-01-01

    Between 2004 and 2012, US funding for the biomedical sciences decreased to historic lows. Health-related research was crippled by receiving only 1/20th of overall federal scientific funding. Despite the current funding climate, there is increased pressure on academic radiology programs to establish productive research programs. Whereas larger programs have resources that can be utilized at their institutions, small to medium-sized programs often struggle with lack of infrastructure and support. To address these concerns, the Association of University Radiologists' Radiology Research Alliance developed a task force to explore any untapped research productivity potential in these smaller radiology departments. We conducted an online survey of faculty at smaller clinically funded programs and found that while they were interested in doing research and felt it was important to the success of the field, barriers such as lack of resources and time were proving difficult to overcome. One potential solution proposed by this task force is a collaborative structured research model in which multiple participants from multiple institutions come together in well-defined roles that allow for an equitable distribution of research tasks and pooling of resources and expertise. Under this model, smaller programs will have an opportunity to share their unique perspective on how to address research topics and make a measureable impact on the field of radiology as a whole. Through a health services focus, projects are more likely to succeed in the context of limited funding and infrastructure while simultaneously providing value to the field. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  7. Livestock and land: trends, status and research opportunities

    NASA Astrophysics Data System (ADS)

    Herrero, M.; Cecile, G.

    2017-12-01

    Livestock are one of the largest users of land. The use vast areas of rangelands and pasturelands and use a third of the global cropland for feed production. The demand of rlivestock products is growing at an accelerated rate due to large increases in income and urbanisation, primarily in the developing world. While most expansion is occuring the the poultry and pork sectors, ruminant meat and milk are also increasing significantly. There is concern as to how to manage the environmental footprints of these very dynamic systems. At the same, time, significnat opportunities to intensify land use in the the livestock sector exist, primarily in grasslands. This paper gives an overview of the trends in land use in the global livestock sector, assess the status of supply and demand of livestock products and how these might be met in the future and cocludes by proposing a research agenda with key areas that merit more attention from biophysical, social and economic scientists.

  8. 45 CFR 46.207 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...: science, medicine, ethics, law) and following opportunity for public review and comment, including a public meeting announced in the Federal Register, has determined either: (1) That the research in fact...

  9. 45 CFR 46.207 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...: science, medicine, ethics, law) and following opportunity for public review and comment, including a public meeting announced in the Federal Register, has determined either: (1) That the research in fact...

  10. 34 CFR 97.407 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... panel of experts in pertinent disciplines (for example: science, medicine, education, ethics, law) and following opportunity for public review and comment, has determined either that— (1) The research in fact...

  11. 34 CFR 97.407 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... panel of experts in pertinent disciplines (for example: science, medicine, education, ethics, law) and following opportunity for public review and comment, has determined either that— (1) The research in fact...

  12. 34 CFR 97.407 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... panel of experts in pertinent disciplines (for example: science, medicine, education, ethics, law) and following opportunity for public review and comment, has determined either that— (1) The research in fact...

  13. 45 CFR 46.207 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: science, medicine, ethics, law) and following opportunity for public review and comment, including a public meeting announced in the Federal Register, has determined either: (1) That the research in fact...

  14. 34 CFR 97.407 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... panel of experts in pertinent disciplines (for example: science, medicine, education, ethics, law) and following opportunity for public review and comment, has determined either that— (1) The research in fact...

  15. 45 CFR 46.207 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...: science, medicine, ethics, law) and following opportunity for public review and comment, including a public meeting announced in the Federal Register, has determined either: (1) That the research in fact...

  16. 34 CFR 97.407 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... panel of experts in pertinent disciplines (for example: science, medicine, education, ethics, law) and following opportunity for public review and comment, has determined either that— (1) The research in fact...

  17. 45 CFR 46.207 - Research not otherwise approvable which presents an opportunity to understand, prevent, or...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: science, medicine, ethics, law) and following opportunity for public review and comment, including a public meeting announced in the Federal Register, has determined either: (1) That the research in fact...

  18. Turning Data Into Information: Opportunities to Advance Rehabilitation Quality, Research, and Policy.

    PubMed

    Bettger, Janet Prvu; Nguyen, Vu Q C; Thomas, J George; Guerrier, Tami; Yang, Qing; Hirsch, Mark A; Pugh, Terrence; Harris, Gabrielle; Eller, Mary Ann; Pereira, Carol; Hamm, Deanna; Rinehardt, Eric A; Shall, Matthew; Niemeier, Janet P

    2018-06-01

    Attention to health care quality and safety has increased dramatically. The internal focus of an organization is not without influence from external policy and research findings. Compared with other specialties, efforts to align and advance rehabilitation research, practice, and policy using electronic health record data are in the early stages. This special communication defines quality, applies the dimensions of quality to rehabilitation, and illustrates the feasibility and utility of electronic health record data for research on rehabilitation care quality and outcomes. Using data generated at the point of care provides the greatest opportunity for improving the quality of health care, producing generalizable evidence to inform policy and practice, and ultimately benefiting the health of the populations served. Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  19. Human factors opportunities to improve Ohio's transportation system : final report, June 2005.

    DOT National Transportation Integrated Search

    2005-06-01

    The aim of this study was to identify opportunities to apply human factors principles and research to improve : Ohios transportation system. The Office of Traffic Engineering assigned thirteen topic areas to provide information : and the study was...

  20. Educational opportunities within the NASA specialized center of research and training in gravitational biology

    NASA Technical Reports Server (NTRS)

    Guikema, James A.; Spooner, Brian S.

    1994-01-01

    The NASA Specialized Center of Research and Training (NSCORT) in Gravitational Biology was established at Kansas State University, supported through NASA's Life Science Division, Office of Space Science and Applications. Educational opportunities, associated with each of the research projects which form the nucleus of the Center, are complemented by program enrichments such as scholar exchanges and linkages to other NASA and commercial programs. The focus of this training program, and a preliminary assessment of its successes, are described.

  1. A scoping study to identify opportunities to advance the ethical implementation and scale-up of HIV treatment as prevention: priorities for empirical research.

    PubMed

    Knight, Rod; Small, Will; Pakula, Basia; Thomson, Kimberly; Shoveller, Jean

    2014-07-03

    Despite the evidence showing the promise of HIV treatment as prevention (TasP) in reducing HIV incidence, a variety of ethical questions surrounding the implementation and "scaling up" of TasP have been articulated by a variety of stakeholders including scientists, community activists and government officials. Given the high profile and potential promise of TasP in combatting the global HIV epidemic, an explicit and transparent research priority-setting process is critical to inform ongoing ethical discussions pertaining to TasP. We drew on the Arksey and O'Malley framework for conducting scoping review studies as well as systematic approaches to identifying empirical and theoretical gaps within ethical discussions pertaining to population-level intervention implementation and scale up. We searched the health science database PubMed to identify relevant peer-reviewed articles on ethical and implementation issues pertaining to TasP. We included English language articles that were published after 2009 (i.e., after the emergence of causal evidence within this field) by using search terms related to TasP. Given the tendency for much of the criticism and support of TasP to occur outside the peer-reviewed literature, we also included grey literature in order to provide a more exhaustive representation of how the ethical discussions pertaining to TasP have and are currently taking place. To identify the grey literature, we systematically searched a set of search engines, databases, and related webpages for keywords pertaining to TasP. Three dominant themes emerged in our analysis with respect to the ethical questions pertaining to TasP implementation and scale-up: (a) balancing individual- and population-level interests; (b) power relations within clinical practice and competing resource demands within health care systems; (c) effectiveness considerations and socio-structural contexts of HIV treatment experiences within broader implementation contexts. Ongoing research

  2. A scoping study to identify opportunities to advance the ethical implementation and scale-up of HIV treatment as prevention: priorities for empirical research

    PubMed Central

    2014-01-01

    Background Despite the evidence showing the promise of HIV treatment as prevention (TasP) in reducing HIV incidence, a variety of ethical questions surrounding the implementation and “scaling up” of TasP have been articulated by a variety of stakeholders including scientists, community activists and government officials. Given the high profile and potential promise of TasP in combatting the global HIV epidemic, an explicit and transparent research priority-setting process is critical to inform ongoing ethical discussions pertaining to TasP. Methods We drew on the Arksey and O’Malley framework for conducting scoping review studies as well as systematic approaches to identifying empirical and theoretical gaps within ethical discussions pertaining to population-level intervention implementation and scale up. We searched the health science database PubMed to identify relevant peer-reviewed articles on ethical and implementation issues pertaining to TasP. We included English language articles that were published after 2009 (i.e., after the emergence of causal evidence within this field) by using search terms related to TasP. Given the tendency for much of the criticism and support of TasP to occur outside the peer-reviewed literature, we also included grey literature in order to provide a more exhaustive representation of how the ethical discussions pertaining to TasP have and are currently taking place. To identify the grey literature, we systematically searched a set of search engines, databases, and related webpages for keywords pertaining to TasP. Results Three dominant themes emerged in our analysis with respect to the ethical questions pertaining to TasP implementation and scale-up: (a) balancing individual- and population-level interests; (b) power relations within clinical practice and competing resource demands within health care systems; (c) effectiveness considerations and socio-structural contexts of HIV treatment experiences within broader

  3. Opportunities for public health communication, intervention, and future research on breast cancer in younger women.

    PubMed

    Buchanan, Natasha; Roland, Katherine B; Rodriguez, Juan L; Miller, Jacqueline W; Fairley, Temeika

    2013-04-01

    Approximately 6% of breast cancers in the United States occur in women under the age of 40 years. Compared with women ≥40 years of age, younger women are diagnosed at later stages, have higher rates of recurrence and death, and may be predisposed to secondary breast or ovarian cancer. An informal meeting of experts discussed opportunities for research and public health communication related to breast cancer among young (<40 and/or premenopausal) women. In September 2011, the Centers for Disease Control and Prevention hosted 18 experts in oncology, genetics, behavioral science, survivorship and advocacy, public health, communication, ethics, nutrition, physical activity, and environmental health. They (1) reviewed research and programmatic knowledge on risk and preventive factors, early detection, and survivorship; and (2) discussed ideas for research, communication, and programmatic efforts related to young women diagnosed with or at risk for early onset breast cancer. Levels of evidence and themes for future research regarding risk and preventive factors, including exposures, were discussed. Early detection strategies, including screening, risk assessment, and genetic counseling, as well as survivorship issues, follow-up care, fertility and reproductive health, and psychosocial care were highlighted. Community and academic researchers, providers, advocates, and the federal public health community discussed strategies and opportunities for this unique population. Although the evidence is limited, future research and communication activities may be useful to organize future public health initiatives.

  4. Artemisinin-Resistant Malaria: Research Challenges, Opportunities, and Public Health Implications

    PubMed Central

    Fairhurst, Rick M.; Nayyar, Gaurvika M. L.; Breman, Joel G.; Hallett, Rachel; Vennerstrom, Jonathan L.; Duong, Socheat; Ringwald, Pascal; Wellems, Thomas E.; Plowe, Christopher V.; Dondorp, Arjen M.

    2012-01-01

    Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the emergence of parasite resistance to all partner drugs, threaten to place millions of patients at risk of inadequate treatment of malaria. Recognizing the significance and immediacy of this possibility, the Fogarty International Center and the National Institute of Allergy and Infectious Diseases of the U.S. National Institutes of Health convened a conference in November 2010 to bring together the diverse array of stakeholders responding to the growing threat of artemisinin resistance, including scientists from malarious countries in peril. This conference encouraged and enabled experts to share their recent unpublished data from studies that may improve our understanding of artemisinin resistance. Conference sessions addressed research priorities to forestall artemisinin resistance and fostered collaborations between field- and laboratory-based researchers and international programs, with the aim of translating new scientific evidence into public health solutions. Inspired by this conference, this review summarizes novel findings and perspectives on artemisinin resistance, approaches for translating research data into relevant public health information, and opportunities for interdisciplinary collaboration to combat artemisinin resistance. PMID:22855752

  5. Artemisinin-resistant malaria: research challenges, opportunities, and public health implications.

    PubMed

    Fairhurst, Rick M; Nayyar, Gaurvika M L; Breman, Joel G; Hallett, Rachel; Vennerstrom, Jonathan L; Duong, Socheat; Ringwald, Pascal; Wellems, Thomas E; Plowe, Christopher V; Dondorp, Arjen M

    2012-08-01

    Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the emergence of parasite resistance to all partner drugs, threaten to place millions of patients at risk of inadequate treatment of malaria. Recognizing the significance and immediacy of this possibility, the Fogarty International Center and the National Institute of Allergy and Infectious Diseases of the U.S. National Institutes of Health convened a conference in November 2010 to bring together the diverse array of stakeholders responding to the growing threat of artemisinin resistance, including scientists from malarious countries in peril. This conference encouraged and enabled experts to share their recent unpublished data from studies that may improve our understanding of artemisinin resistance. Conference sessions addressed research priorities to forestall artemisinin resistance and fostered collaborations between field- and laboratory-based researchers and international programs, with the aim of translating new scientific evidence into public health solutions. Inspired by this conference, this review summarizes novel findings and perspectives on artemisinin resistance, approaches for translating research data into relevant public health information, and opportunities for interdisciplinary collaboration to combat artemisinin resistance.

  6. Student Activism as a Vehicle for Change on College Campuses: Emerging Research and Opportunities

    ERIC Educational Resources Information Center

    Miller, Michael T.; Tolliver, David V., III

    2017-01-01

    Civic engagement initiatives and activities are crucial to the progression of modern society. By raising awareness of social issues and problems, citizens can make a greater impact and have their voices be heard. "Student Activism as a Vehicle for Change on College Campuses: Emerging Research and Opportunities" is a critical source of…

  7. New NSLP guidelines: challenges and opportunities for nutrition education practitioners and researchers.

    PubMed

    Byker, Carmen J; Pinard, Courtney A; Yaroch, Amy L; Serrano, Elena L

    2013-01-01

    The recent revisions of the National School Lunch Program (NSLP) requirements are designed to align with the 2010 Dietary Guidelines for Americans. The introduction and implementation of the new NSLP has been received with positive and negative reactions from school food professionals, students, parents, and teachers. To promote student health, this is an important time for policy makers, practitioners, and researchers to implement and evaluate strategies to support the new NSLP guidelines. The purpose of this viewpoint was to outline the new NSLP guidelines and discuss challenges and opportunities for implementation, strategies for practice, and future research questions. Copyright © 2013 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  8. Identifying opportunities for collaboration and growth of genetic counseling services in the Asia Region.

    PubMed

    Laurino, Mercy Y; Sternen, Darci L; Thompson, Jennifer K; Leppig, Kathleen A

    2017-07-01

    The Genetic Counseling Pre-Conference Workshop (GCPCW) was held on September 16, 2015, in Hanoi, Vietnam. We report the GCPCW outcomes obtained from pre- and post-conference questionnaires, case-review breakout session, and an open discussion of needs for genetic counseling services in the Asia region. The GCPCW participants completed questionnaires with closed- and open-ended questions regarding the status and needs of providing genetic counseling services in Asia. Utilizing thematic content analysis, common themes shared during the case-review breakout session are summarized and survey results are tabulated. Of the 71 participants, pre- and post-conference questionnaires were returned by 57 (80%) and 44 (62%) individuals, respectively. Of the 42 participants who did not identify themselves as students in training, 36 (86%) stated they are currently providing genetic counseling services. Participants cited that the most useful information obtained during the GCPCW related to the status of genetic counseling services in the region, discovery of shared challenges, professional networking, and the need to establish genetic counseling training programs and its accreditation. The GCPCW provided a collaborative forum to address current challenges and needs of genetic counseling services in the region. Strategies were identified to foster genetic counseling training and clinical service opportunities.

  9. Composite Artistry Meets Facial Recognition Technology: Exploring the Use of Facial Recognition Technology to Identify Composite Images

    DTIC Science & Technology

    2011-09-01

    be submitted into a facial recognition program for comparison with millions of possible matches, offering abundant opportunities to identify the...to leverage the robust number of comparative opportunities associated with facial recognition programs. This research investigates the efficacy of...combining composite forensic artistry with facial recognition technology to create a viable investigative tool to identify suspects, as well as better

  10. Using EMIS to Identify Top Opportunities for Commercial Building Efficiency

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, Guanjing; Singla, Rupam; Granderson, Jessica

    Energy Management and Information Systems (EMIS) comprise a broad family of tools and services to manage commercial building energy use. These technologies offer a mix of capabilities to store, display, and analyze energy use and system data, and in some cases, provide control. EMIS technologies enable 10–20 percent site energy savings in best practice implementations. Energy Information System (EIS) and Fault Detection and Diagnosis (FDD) systems are two key technologies in the EMIS family. Energy Information Systems are broadly defined as the web-based software, data acquisition hardware, and communication systems used to analyze and display building energy performance. At amore » minimum, an EIS provides daily, hourly or sub-hourly interval meter data at the whole-building level, with graphical and analytical capability. Fault Detection and Diagnosis systems automatically identify heating, ventilation, and air-conditioning (HVAC) system or equipment-level performances issues, and in some cases are able to isolate the root causes of the problem. They use computer algorithms to continuously analyze system-level operational data to detect faults and diagnose their causes. Many FDD tools integrate the trend log data from a Building Automation System (BAS) but otherwise are stand-alone software packages; other types of FDD tools are implemented as “on-board” equipment-embedded diagnostics. (This document focuses on the former.) Analysis approaches adopted in FDD technologies span a variety of techniques from rule-based methods to process history-based approaches. FDD tools automate investigations that can be conducted via manual data inspection by someone with expert knowledge, thereby expanding accessibility and breath of analysis opportunity, and also reducing complexity.« less

  11. Identifying fruitful connections between and among researchers and practitioners

    NASA Technical Reports Server (NTRS)

    Feather, Martin S.; Menzies, Tim; Connelly, Judith R.

    2003-01-01

    Many organizations look to research to yield new and improved products and practices. Connecting practitioners who have the need for research results to the researchers producing those results is important to guiding research and utilizing its results. Likewise, connecting researchers working on related topics to one another, and connecting practitioners with related needs to one another, is important to establishing communities of shared interests. We present an approach that helps identify fruitful such connections.

  12. Identifying emerging research collaborations and networks: method development.

    PubMed

    Dozier, Ann M; Martina, Camille A; O'Dell, Nicole L; Fogg, Thomas T; Lurie, Stephen J; Rubinstein, Eric P; Pearson, Thomas A

    2014-03-01

    Clinical and translational research is a multidisciplinary, collaborative team process. To evaluate this process, we developed a method to document emerging research networks and collaborations in our medical center to describe their productivity and viability over time. Using an e-mail survey, sent to 1,620 clinical and basic science full- and part-time faculty members, respondents identified their research collaborators. Initial analyses, using Pajek software, assessed the feasibility of using social network analysis (SNA) methods with these data. Nearly 400 respondents identified 1,594 collaborators across 28 medical center departments resulting in 309 networks with 5 or more collaborators. This low-burden approach yielded a rich data set useful for evaluation using SNA to: (a) assess networks at several levels of the organization, including intrapersonal (individuals), interpersonal (social), organizational/institutional leadership (tenure and promotion), and physical/environmental (spatial proximity) and (b) link with other data to assess the evolution of these networks.

  13. Forensic medicine: a forgotten world of opportunities and challenges for research.

    PubMed

    Magalhães, Teresa; Santos, Agostinho; Dinis-Oliveira, Ricardo Jorge

    2013-08-01

    Forensic medicine deals with a wide variety of cases. To accomplish the main objectives, this professional field needs to adopt and apply findings from other sciences, namely, different medical specialties and other forensic sciences. The opposite is not yet entirely true due to the fact that forensic medicine deals with cases that are very far away from other medical and scientific interests. It is obvious that this forgotten world of forensic medicine … is also a new world of opportunities and challenges to research in all scientific areas. Copyright © 2013 IMSS. Published by Elsevier Inc. All rights reserved.

  14. A technique for identifying treatment opportunities from western Oregon and Washington forest survey plots.

    Treesearch

    Colin D. MacLean

    1980-01-01

    Identification of opportunities for silvicultural treatment from inventory data is an important objective of Renewable Resources Evaluation in the Pacific Northwest. This paper describes the field plot design and data analysis procedure used by what used to be known as Forest Survey to determine the treatment opportunity associated with each inventory plot in western...

  15. Opportunities for Public Health Communication, Intervention, and Future Research on Breast Cancer in Younger Women

    PubMed Central

    Buchanan, Natasha; Roland, Katherine B.; Rodriguez, Juan L.; Miller, Jacqueline W.; Fairley, Temeika

    2015-01-01

    Background Approximately 6% of breast cancers in the United States occur in women under the age of 40 years. Compared with women ≥ 40 years of age, younger women are diagnosed at later stages, have higher rates of recurrence and death, and may be predisposed to secondary breast or ovarian cancer. An informal meeting of experts discussed opportunities for research and public health communication related to breast cancer among young (< 40 and/or premenopausal) women. Methods In September 2011, the Centers for Disease Control and Prevention hosted 18 experts in oncology, genetics, behavioral science, survivorship and advocacy, public health, communication, ethics, nutrition, physical activity, and environmental health. They (1) reviewed research and programmatic knowledge on risk and preventive factors, early detection, and survivorship; and (2) discussed ideas for research, communication, and programmatic efforts related to young women diagnosed with or at risk for early onset breast cancer. Results Levels of evidence and themes for future research regarding risk and preventive factors, including exposures, were discussed. Early detection strategies, including screening, risk assessment, and genetic counseling, as well as survivorship issues, follow-up care, fertility and reproductive health, and psychosocial care were highlighted. Conclusion Community and academic researchers, providers, advocates, and the federal public health community discussed strategies and opportunities for this unique population. Although the evidence is limited, future research and communication activities may be useful to organize future public health initiatives. PMID:23514347

  16. Opportunities and Challenges of Interdisciplinary Research Career Development: Implementation of a Women’s Health Research Training Program

    PubMed Central

    DOMINO, STEVEN E.; SMITH, YOLANDA R.; JOHNSON, TIMOTHY R.B.

    2007-01-01

    A key component of the National Institutes of Health Roadmap for Medical Research is the development of interdisciplinary research teams. How best to teach and foster interdisciplinary research skills has not been determined. An effort at promoting interdisciplinary research was initiated by the Office of Research on Women’s Health at NIH in 1999. The following year, twelve academic centers were funded to support 56 scholar positions for two to five years under the acronym “BIRCWH: Building Interdisciplinary Research Careers in Women’s Health.” A second cohort of twelve centers, called BIRCWH II, was funded in 2002. In this article, the authors present the experience of the University of Michigan BIRCWH program including a practical approach to dealing with the challenges and opportunities of interdisciplinary research training. Scholars are mentored not only by their primary research advisor, but by a three person mentor team as well as by their peers. All scholars and a core of supportive faculty meet regularly to discuss interdisciplinary research career development and approaches to apply knowledge in new ways. Of the original cohort of 10 scholars at the University of Michigan, 7 have achieved independent research funding. Challenges include arranging times to meet, developing a common language and knowledge base, dealing proactively with expectations and misunderstandings, focusing on a conceptual model, and providing timely feedback. PMID:17388742

  17. The globalization of public health, I: Threats and opportunities.

    PubMed Central

    Yach, D; Bettcher, D

    1998-01-01

    The globalization of public health poses new threats to health but also holds important opportunities in the coming century. This commentary identifies the major threats and opportunities presented by the process of globalization and emphasizes the need for transnational public health approaches to take advantage of the positive aspects of global change and to minimize the negative ones. Transnational public health issues are areas of mutual concern for the foreign policies of all countries. These trends indicate a need for cross-national comparisons (e.g., in the areas of health financing and policy development) and for the development of a transnational research agenda in public health. PMID:9585736

  18. Advancing the practice of health impact assessment in Canada: Obstacles and opportunities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCallum, Lindsay C., E-mail: lindsay.mccallum@mail.utoronto.ca; Intrinsik Environmental Sciences Inc., 6605 Hurontario Street, Mississauga, Ontario L5T0A3; Ollson, Christopher A., E-mail: collson@intrinsik.com

    Health Impact Assessment (HIA) is recognized as a useful tool that can identify potential health impacts resulting from projects or policy initiatives. Although HIA has become an established practice in some countries, it is not yet an established practice in Canada. In order to enable broader support for HIA, this study provides a comprehensive review and analysis of the peer-reviewed and gray literature on the state of HIA practice. The results of this review revealed that, although there is an abundance of publications relating to HIA, there remains a lack of transparent, consistent and reproducible approaches and methods throughout themore » process. Findings indicate a need for further research and development on a number of fronts, including: 1) the nature of HIA triggers; 2) consistent scoping and stakeholder engagement approaches; 3) use of evidence and transparency of decision-making; 4) reproducibility of assessment methods; 5) monitoring and evaluation protocols; and, 6) integration within existing regulatory frameworks. Addressing these issues will aid in advancing the more widespread use of HIA in Canada. - Highlights: • Reviewed current state of practice in the field of HIA • Identified key obstacles and opportunities for HIA advancement • Major issues include lack of consistent approach and methodology. • No national regulatory driver hinders opportunity for widespread use of HIA. • Identified research opportunities vital to developing HIA practice in Canada.« less

  19. Assessing the Status of Professional Learning Opportunities in EARCOS Member Schools

    ERIC Educational Resources Information Center

    Hardeman, Mark Brandon

    2016-01-01

    The purpose of this study was to assess the extent to which professional development programs within EARCOS member schools are consistent with research-based principles of effective practice. In addition, this study sought to identify the professional development opportunities that are being provided to EARCOS teachers. Finally, this study…

  20. Resource Development Opportunities for the Association of Leadership Educators: Phase One

    ERIC Educational Resources Information Center

    Noble, Donnette J.; Matesi, Lyna; Breen, Jennifer Moss; Horstmeier, Robin Peiter; Anderson, Dennis M.; Allen, Stuart; Pedigo, Leslie

    2016-01-01

    This application brief shares Phase One of an action research project for the Association of Leadership Educators. This project demonstrates how a member-based association can successfully engage its members in terms of identifying needs, defining strategic priorities, and detecting resource development opportunities. This body of work has various…

  1. Career opportunities in clinical engineering.

    PubMed

    Morse, W A

    1992-01-01

    The varied career opportunities open to clinical engineers are described in this paper. Many of these opportunities are within the medical device industry in research, development, manufacturing design, regulatory activities, production, operations, sales, marketing, service, and management. Additional opportunities are available in hospitals, with the Veterans Administration, or working as an entrepreneur or a consultant. Each of these careers requires specific training and skills, and they all require a fundamental scientific knowledge of physical principles and mathematics. Research and management, however, require different educational preparation. The research emphasis should be on theoretical principles and creativity; the management emphasis should be on financial and labor problems. In all clinical engineering careers, the individual is a problem solver.

  2. Identifying Global Research Priorities for Learning Disabilities

    ERIC Educational Resources Information Center

    Johnson, Evelyn S.; Webb, M. Brady

    2017-01-01

    Estimates of the global prevalence of learning disabilities (LD) range from 5-17%. A host of negative outcomes have been associated with LD, particularly for people of low socioeconomic status within developed nations and for people in developing nations. The goal of this study was to identify global research priorities that address the persistent…

  3. Network Virtualization - Opportunities and Challenges for Operators

    NASA Astrophysics Data System (ADS)

    Carapinha, Jorge; Feil, Peter; Weissmann, Paul; Thorsteinsson, Saemundur E.; Etemoğlu, Çağrı; Ingþórsson, Ólafur; Çiftçi, Selami; Melo, Márcio

    In the last few years, the concept of network virtualization has gained a lot of attention both from industry and research projects. This paper evaluates the potential of network virtualization from an operator's perspective, with the short-term goal of optimizing service delivery and rollout, and on a longer term as an enabler of technology integration and migration. Based on possible scenarios for implementing and using network virtualization, new business roles and models are examined. Open issues and topics for further evaluation are identified. In summary, the objective is to identify the challenges but also new opportunities for telecom operators raised by network virtualization.

  4. National Priorities: Transdisciplinary Research into Detecting and Controlling Lead in Drinking Water

    EPA Pesticide Factsheets

    EPA seeks applications for research on identifying communities at high risk of adverse health effects of lead in drinking water, identifying opportunities to mitigate these risks, conduct efforts to inform interested parties of these risks & opportunities.

  5. Time-driven activity-based costing to identify opportunities for cost reduction in pediatric appendectomy.

    PubMed

    Yu, Yangyang R; Abbas, Paulette I; Smith, Carolyn M; Carberry, Kathleen E; Ren, Hui; Patel, Binita; Nuchtern, Jed G; Lopez, Monica E

    2016-12-01

    As reimbursement programs shift to value-based payment models emphasizing quality and efficient healthcare delivery, there exists a need to better understand process management to unearth true costs of patient care. We sought to identify cost-reduction opportunities in simple appendicitis management by applying a time-driven activity-based costing (TDABC) methodology to this high-volume surgical condition. Process maps were created using medical record time stamps. Labor capacity cost rates were calculated using national median physician salaries, weighted nurse-patient ratios, and hospital cost data. Consumable costs for supplies, pharmacy, laboratory, and food were derived from the hospital general ledger. Time-driven activity-based costing resulted in precise per-minute calculation of personnel costs. Highest costs were in the operating room ($747.07), hospital floor ($388.20), and emergency department ($296.21). Major contributors to length of stay were emergency department evaluation (270min), operating room availability (395min), and post-operative monitoring (1128min). The TDABC model led to $1712.16 in personnel costs and $1041.23 in consumable costs for a total appendicitis cost of $2753.39. Inefficiencies in healthcare delivery can be identified through TDABC. Triage-based standing delegation orders, advanced practice providers, and same day discharge protocols are proposed cost-reducing interventions to optimize value-based care for simple appendicitis. II. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Recent advances in the field of ovarian tissue cryopreservation and opportunities for research.

    PubMed

    Ladanyi, Camille; Mor, Amir; Christianson, Mindy S; Dhillon, Namisha; Segars, James H

    2017-06-01

    The purpose of this study was to summarize the latest advances and successes in the field of ovarian tissue cryopreservation while identifying gaps in current knowledge that suggest opportunities for future research. A systematic review was performed according to PRISMA guidelines for all relevant full-text articles in PubMed published in English that reviewed or studied historical or current advancements in ovarian tissue cryopreservation and auto-transplantation techniques. Ovarian tissue auto-transplantation in post-pubertal women is capable of restoring fertility with over 80 live births currently reported with a corresponding pregnancy rate of 23 to 37%. The recently reported successes of live births from transplants, both in orthotopic and heterotopic locations, as well as the emerging methods of in vitro maturation (IVM), in vitro culture of primordial follicles, and possibility of in vitro activation (IVA) suggest new fertility options for many women and girls. Vitrification, as an ovarian tissue cryopreservation technique, has also demonstrated successful live births and may be a more cost-effective method to freezing with less tissue injury. Further, transplantation via the artificial ovary with an extracellular tissue matrix (ECTM) scaffolding as well as the effects of sphingosine-1-phosphate (SIP) and fibrin modified with heparin-binding peptide (HBP), heparin, and a vascular endothelial growth factor (VEGF) have demonstrated important advancements in fertility preservation. As a fertility preservation method, ovarian tissue cryopreservation and auto-transplantation are currently considered experimental, but future research may pave the way for these modalities to become a standard of care for women facing the prospect of sterility from ovarian damage.

  7. Good and Bad Research Collaborations: Researchers' Views on Science and Ethics in Global Health Research.

    PubMed

    Parker, Michael; Kingori, Patricia

    2016-01-01

    There has been a dramatic rise in the scale and scope of collaborative global health research. A number of structural and scientific factors explain this growth and there has been much discussion of these in the literature. Little, if any, attention has been paid, however, to the factors identified by scientists and other research actors as important to successful research collaboration. This is surprising given that their decisions are likely to play a key role in the sustainability and effectiveness of global health research initiatives. In this paper, we report on qualitative research with leading scientists involved in major international research collaborations about their views on good and bad collaborations and the factors that inform their decision-making about joining and participating actively in research networks. We identify and discuss eight factors that researchers see as essential in judging the merits of active participation in global health research collaborations: opportunities for active involvement in cutting-edge, interesting science; effective leadership; competence of potential partners in and commitment to good scientific practice; capacity building; respect for the needs, interests and agendas of partners; opportunities for discussion and disagreement; trust and confidence; and, justice and fairness in collaboration. Our findings suggest that the sustainability and effectiveness of global health research collaborations has an important ethical or moral dimension for the research actors involved.

  8. The Use of Citation Counting to Identify Research Trends

    ERIC Educational Resources Information Center

    Rothman, Harry; Woodhead, Michael

    1971-01-01

    The analysis and application of manpower statistics to identify some long-term international research trends in economic entomology and pest conrol are described. Movements in research interests, particularly towards biological methods of control, correlations between these sectors, and the difficulties encountered in the construction of a…

  9. Research opportunities in human behavior and performance

    NASA Technical Reports Server (NTRS)

    Christensen, J. M. (Editor); Talbot, J. M. (Editor)

    1985-01-01

    Extant information on the subject of psychological aspects of manned space flight are reviewed; NASA's psychology research program is examined; significant gaps in knowledge are identified; and suggestions are offered for future research program planning. Issues of human behavior and performance related to the United States space station, to the space shuttle program, and to both near and long term problems of a generic nature in applicable disciplines of psychology are considered. Topics covered include: (1) human performance requirements for a 90 day mission; (2) human perceptual, cognitive, and motor capabilities and limitations in space; (3) crew composition, individual competencies, crew competencies, selection criteria, and special training; (4) environmental factors influencing behavior; (5) psychosocial aspects of multiperson space crews in long term missions; (6) career determinants in NASA; (7) investigational methodology and equipment; and (8) psychological support.

  10. Refining Current Scientific Priorities and Identifying New Scientific Gaps in HIV-Related Heart, Lung, Blood, and Sleep Research.

    PubMed

    Twigg, Homer L; Crystal, Ronald; Currier, Judith; Ridker, Paul; Berliner, Nancy; Kiem, Hans-Peter; Rutherford, George; Zou, Shimian; Glynn, Simone; Wong, Renee; Peprah, Emmanuel; Engelgau, Michael; Creazzo, Tony; Colombini-Hatch, Sandra; Caler, Elisabet

    2017-09-01

    The National Heart, Lung, and Blood Institute (NHLBI) AIDS Program's goal is to provide direction and support for research and training programs in areas of HIV-related heart, lung, blood, and sleep (HLBS) diseases. To better define NHLBI current HIV-related scientific priorities and with the goal of identifying new scientific priorities and gaps in HIV-related HLBS research, a wide group of investigators gathered for a scientific NHLBI HIV Working Group on December 14-15, 2015, in Bethesda, MD. The core objectives of the Working Group included discussions on: (1) HIV-related HLBS comorbidities in the antiretroviral era; (2) HIV cure; (3) HIV prevention; and (4) mechanisms to implement new scientific discoveries in an efficient and timely manner so as to have the most impact on people living with HIV. The 2015 Working Group represented an opportunity for the NHLBI to obtain expert advice on HIV/AIDS scientific priorities and approaches over the next decade.

  11. Strategic Moments: IDENTIFYING OPPORTUNITIES TO ENGAGE CLIENTS IN ATTENDING CARDIAC REHABILITATION AND MAINTAINING LIFESTYLE CHANGES.

    PubMed

    Fletcher, Susan Marilyn; McBurney, Helen

    2016-01-01

    There has been extensive investigation of attendance rates at cardiac rehabilitation (CR) but little attention to client reasoning around attendance. This study explored decision-making drivers for attendance or nonattendance at CR programs in rural Victoria, Australia. All new patients referred to the CR programs at either the local hospital or community health service over a 6-month period were invited to participate and were interviewed before, after, and at 6 months post-CR. Content analysis was used to identify and group common themes that emerged from the semistructured interviews. Eighty-four of the 114 patients referred agreed to participate in the study. Multiple barriers or facilitators affected the decisions of all clients. Three themes were identified that reflected the participant decision-making experience: (1) invitation and information about participation in CR; (2) person-centered approach to CR provision; and (3) ongoing support needs. Significant decision-making points identified were after the cardiac event; before and after hospital-based CR; before and after community-based CR; and at 6 months after the cardiac event. At any time there is a risk that the client can become lost or disengaged in the service system, but providing contact at these points can allow them to reengage. This study provided the opportunity to hear participant voices, describing their decisions around CR attendance after a cardiac event. They highlighted the complexity of issues confronting them and suggested improvements to optimize their attendance and to maintain lifestyle changes.

  12. Melanoma central nervous system metastases: current approaches, challenges, and opportunities

    PubMed Central

    Cohen, Justine V.; Tawbi, Hussain; Margolin, Kim A.; Amravadi, Ravi; Bosenberg, Marcus; Brastianos, Priscilla K.; Chiang, Veronica L.; de Groot, John; Glitza, Isabella C.; Herlyn, Meenhard; Holmen, Sheri L.; Jilaveanu, Lucia B.; Lassman, Andrew; Moschos, Stergios; Postow, Michael A.; Thomas, Reena; Tsiouris, John A.; Wen, Patrick; White, Richard M.; Turnham, Timothy; Davies, Michael A.; Kluger, Harriet M.

    2017-01-01

    Summary Melanoma central nervous system metastases are increasing, and the challenges presented by this patient population remain complex. In December 2015, the Melanoma Research Foundation and the Wistar Institute hosted the First Summit on Melanoma Central Nervous System (CNS) Metastases in Philadelphia, Pennsylvania. Here, we provide a review of the current status of the field of melanoma brain metastasis research; identify key challenges and opportunities for improving the outcomes in patients with melanoma brain metastases; and set a framework to optimize future research in this critical area. PMID:27615400

  13. Developing Education Research Competencies in Mathematics Teachers through TRAIL: Teacher-Researcher Alliance for Investigating Learning

    ERIC Educational Resources Information Center

    Koichu, Boris; Pinto, Alon

    2018-01-01

    This theoretical article explores an issue of developing education research competencies in mathematics teachers through their involvement in mathematics education research. We first argue that the development of education research competencies is beneficial for the teachers' professional growth. We then identify opportunities for mathematics…

  14. Research peer exchange.

    DOT National Transportation Integrated Search

    2005-10-01

    The Montana Department of Transportation hosted a research management peer exchange October 3-7, 2005. The : objectives of the peer exchange were to: identify strengths, challenges, and opportunities for the information services : component of MDT...

  15. Forest carbon research in Inner Mongolia: current knowledge, opportunity and challenge

    NASA Astrophysics Data System (ADS)

    Shuyong, Li; Mei, Huang; Shenggong, Li

    2014-03-01

    Carbon storage in forests in Inner Mongolia Autonomous Region plays a significant role in the terrestrial carbon budget due to its largest forest coverage and forest growing stock among all the provinces in China. Nevertheless, scientific research on forest carbon is comparatively less as compared with the research on the main ecosystem, steppe in this area. We are still short of knowledge of forest carbon sequestration's rate, mechanism and potential in the area. Now we are conducting a research program aiming at making clear the above scientific issues. So knowing well previous research work and key findings is essential and helpful for our underway study. In this paper we reviewed the current knowledge, opportunity and challenges of forest carbon research in Inner Mongolia. The total carbon storage in forest of this region increased significantly from 0.417Pg carbon in 1949 to 0.719Pg carbon in 2008 with an annual increase of 2.842Tg~5.226Tg carbon and a dramatically increment of carbon storage in shrub. Carbon storage varied with dominant tree species, forest age and forest growth situation with an average forest carbon density of 42.68 t-C.hm-2, displaying a downtrend before 1980 and later a slow smooth uptrend. It is suggested that increase in vegetation carbon sequestration potential be achieved through selection of plant species and forest management.

  16. Space environmental effects on polymer composites: Research needs and opportunities

    NASA Technical Reports Server (NTRS)

    Jang, Bor Z.; Bianchi, J.; Liu, Y. M.; Chang, C. P.

    1993-01-01

    The long-term performance of polymer-based composites in the space environment is discussed. Both thermoset and thermoplastic matrix composites are included in this discussion. Previous efforts on the space environmental effects on composites are briefly reviewed. Focus of this review is placed on the effects of hygrothermal stresses, atomic oxygen, ultraviolet (UV), and space debris/micrometeoroid impacts along with the potential synergism. Potential approaches to estimating the residual strength of polymer composites after exposure to atomic oxygen erosion or space debris/micrometeoroid impact are evaluated. New ground-based data are then utilized to illustrate the effects of atomic oxygen and thermal cycling on the failure behavior of polymer composites. Finally, research needs, challenges, and opportunities in the field of space environmental effects on composite materials are highlighted.

  17. Internships, employment opportunities, and research grants

    USGS Publications Warehouse

    2008-01-01

    As an unbiased, multidisciplinary science organization that focuses on biology, geography, geology, geospatial information, and water, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the landscape, our natural resources, and the natural hazards that threaten us. Opportunities for undergraduate and graduate students and faculty to participate in USGS science are available through the selected programs described below. Please note: U.S. citizenship is required for all positions, although some noncitizens may be eligible in rare circumstances.

  18. Using health technology assessment to identify gaps in evidence and inform study design for comparative effectiveness research.

    PubMed

    Tunis, Sean R; Turkelson, Charles

    2012-12-01

    Health technology assessment (HTA) is primarily used as a tool to ensure that clinical and policy decisions are made with the benefit of a systematic analysis of all completed research. This article describes the progress and potential for HTA reports to improve the quality and relevance of future research and to better serve the information needs of patients, clinicians, payers, and other decision makers. We conducted a review of the current published literature and working papers describing past, ongoing, and future initiatives that rely on HTA reports to identify gaps in evidence and improve the design of future research. Although still in a developmental stage, significant progress is under way to improve methods for using HTA reports for the systematic identification of research gaps, prioritization of future research, and improvement of study designs. Several well-defined frameworks have been developed to assist those who produce HTA to become more effective in these additional domains of work. A recurring element of this work is the importance of meaningfully involving stakeholders in the process of defining future research needs and designing studies to address them. Patients, clinicians, and payers are important audiences for completed research and are now recognized as serving an important role in determining what future research is needed. There are substantial opportunities to improve the quality, relevance, and efficiency of clinical research. Recent efforts are beginning to demonstrate the potential to build on the work invested in developing HTA reports to provide a roadmap toward these objectives.

  19. International tuberculosis research collaborations within Asia.

    PubMed

    Molton, James S; Singh, Shweta; Chen, Ling Jun; Paton, Nicholas I

    2017-09-07

    Asia bears more than half the global tuberculosis (TB) burden. Economic development in the region has increased available funding for biomedical research and opportunity for collaboration. We explored the extent of international tuberculosis research collaborations between institutions within Asia. We conducted a Pubmed search for all articles with tuberculosis in the title published during a 12 month period with at least one author affiliation listed in Asia, then identified international collaborations from institution websites and internet searches. We identified 99 international collaborations involving an institution within Asia, of which only 8 (8.1%) were collaborations between Asian institutions. The remainder were with institutions outside of Asia. The paucity of intra-Asian international research collaboration represents a lost opportunity to optimise regional research funding, capacity building and the development of an Asia-relevant TB research agenda.

  20. Barriers and Opportunities Related to Whole Grain Foods in Minnesota School Foodservice

    ERIC Educational Resources Information Center

    Hesse, David; Braun, Curtis; Dostal, Allison; Jeffery, Robert; Marquart, Len

    2009-01-01

    Purpose/Objectives: The purpose of this research was to identify barriers and opportunities associated with the introduction of whole grain foods into school cafeterias. The primary objective was to elicit input from school foodservice personnel (SFP) regarding their experiences in ordering, purchasing, preparing, and serving whole grain foods in…

  1. Smartphones Offer New Opportunities in Clinical Voice Research.

    PubMed

    Manfredi, C; Lebacq, J; Cantarella, G; Schoentgen, J; Orlandi, S; Bandini, A; DeJonckere, P H

    2017-01-01

    Smartphone technology provides new opportunities for recording standardized voice samples of patients and sending the files by e-mail to the voice laboratory. This drastically improves the collection of baseline data, as used in research on efficiency of voice treatments. However, the basic requirement is the suitability of smartphones for recording and digitizing pathologic voices (mainly characterized by period perturbations and noise) without significant distortion. In this experiment, two smartphones (a very inexpensive one and a high-level one) were tested and compared with direct microphone recordings in a soundproof room. The voice stimuli consisted in synthesized deviant voice samples (median of fundamental frequency: 120 and 200 Hz) with three levels of jitter and three levels of added noise. All voice samples were analyzed using PRAAT software. The results show high correlations between jitter, shimmer, and noise-to-harmonics ratio measured on the recordings via both smartphones, the microphone, and measured directly on the sound files from the synthesizer. Smartphones thus appear adequate for reliable recording and digitizing of pathologic voices. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  2. 77 FR 48162 - Announcement of Requirements and Registration for the Challenge To Identify Audacious Goals in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... science and describe current specific research needs and opportunities. The current NEI strategic planning... worldwide. The creativity arising from a variety of new perspectives is expected to generate new research... and Registration for the Challenge To Identify Audacious Goals in Vision Research and Blindness...

  3. Nature-based supportive care opportunities: a conceptual framework.

    PubMed

    Blaschke, Sarah; O'Callaghan, Clare C; Schofield, Penelope

    2018-03-22

    Given preliminary evidence for positive health outcomes related to contact with nature for cancer populations, research is warranted to ascertain possible strategies for incorporating nature-based care opportunities into oncology contexts as additional strategies for addressing multidimensional aspects of cancer patients' health and recovery needs. The objective of this study was to consolidate existing research related to nature-based supportive care opportunities and generate a conceptual framework for discerning relevant applications in the supportive care setting. Drawing on research investigating nature-based engagement in oncology contexts, a two-step analytic process was used to construct a conceptual framework for guiding nature-based supportive care design and future research. Concept analysis methodology generated new representations of understanding by extracting and synthesising salient concepts. Newly formulated concepts were transposed to findings from related research about patient-reported and healthcare expert-developed recommendations for nature-based supportive care in oncology. Five theoretical concepts (themes) were formulated describing patients' reasons for engaging with nature and the underlying needs these interactions address. These included: connecting with what is genuinely valued, distancing from the cancer experience, meaning-making and reframing the cancer experience, finding comfort and safety, and vital nurturance. Eight shared patient and expert recommendations were compiled, which address the identified needs through nature-based initiatives. Eleven additional patient-reported recommendations attend to beneficial and adverse experiential qualities of patients' nature-based engagement and complete the framework. The framework outlines salient findings about helpful nature-based supportive care opportunities for ready access by healthcare practitioners, designers, researchers and patients themselves. © Article author(s) (or their

  4. Opportunity to discuss ethical issues during clinical learning experience.

    PubMed

    Palese, Alvisa; Gonella, Silvia; Destrebecq, Anne; Mansutti, Irene; Terzoni, Stefano; Morsanutto, Michela; Altini, Pietro; Bevilacqua, Anita; Brugnolli, Anna; Canzan, Federica; Ponte, Adriana Dal; De Biasio, Laura; Fascì, Adriana; Grosso, Silvia; Mantovan, Franco; Marognolli, Oliva; Nicotera, Raffaela; Randon, Giulia; Tollini, Morena; Saiani, Luisa; Grassetti, Luca; Dimonte, Valerio

    2018-01-01

    Undergraduate nursing students have been documented to experience ethical distress during their clinical training and felt poorly supported in discussing the ethical issues they encountered. Research aims: This study was aimed at exploring nursing students' perceived opportunity to discuss ethical issues that emerged during their clinical learning experience and associated factors. An Italian national cross-sectional study design was performed in 2015-2016. Participants were invited to answer a questionnaire composed of four sections regarding: (1) socio-demographic data, (2) previous clinical learning experiences, (3) current clinical learning experience quality and outcomes, and (4) the opportunity to discuss ethical issues with nurses in the last clinical learning experience (from 0 - 'never' to 3 - 'very much'). Participants and research context: Participants were 9607 undergraduate nursing students who were attending 95 different three-year Italian baccalaureate nursing programmes, located at 27 universities in 15 Italian regions. Ethical considerations: This study was conducted in accordance with the Human Subject Research Ethics Committee guidelines after the research protocol was approved by an ethics committee. Overall, 4707 (49%) perceived to have discussed ethical issues 'much' or 'very much'; among the remaining, 3683 (38.3%) and 1217 (12.7%) students reported the perception of having discussed, respectively, 'enough' or 'never' ethical issues emerged in the clinical practice. At the multivariate logistic regression analysis explaining 38.1% of the overall variance, the factors promoting ethical discussion were mainly set at the clinical learning environment levels (i.e. increased learning opportunities, self-directed learning, safety and nursing care quality, quality of the tutorial strategies, competences learned and supervision by a clinical nurse). In contrast, being male was associated with a perception of less opportunity to discuss ethical issues

  5. The experience of Iranian entrepreneurial nurses on the identification of entrepreneurial opportunities: A qualitative study

    PubMed Central

    Jahani, Simin; Abedi, Heidarali; Khoshknab, Masoud Fallahi; Elahi, Nasrin

    2018-01-01

    Background: To respond to the growing and emerging needs of the people in the health sector, the nurses need to develop their working domain from the hospitals to the community and be prepared to provide entrepreneurial roles at different care levels. Thus, to discover how to identify entrepreneurial opportunities in the field of nursing entrepreneurship, a study was conducted with the aim of describing the experiences of Iranian entrepreneurs on the identification of proper opportunities in entrepreneurship. Materials and Methods: This study was a qualitative research in which the Graneheim and Lundman's content analysis was used to collect and analyze the data. Thirteen entrepreneurial nurses were purposefully selected, and the data were collected by unstructured interviews. Results: As a result of data analysis, three main themes were obtained including the resources for opportunity identification and opportunity assessment and identification of proper opportunities. Conclusion: The findings indicate how to identify entrepreneurial opportunities in the field of health by entrepreneurial nurses which is the first step in the entrepreneurial process. Therefore, the findings of this study can be used to educate nurses who are interested in entering the field of nursing entrepreneurship.

  6. The New Commercial Suborbital Vehicles: An Opportunity for Scientific and Microgravity Research

    NASA Astrophysics Data System (ADS)

    Moro-Aguilar, Rafael

    2014-11-01

    As of 2013, a number of companies had announced their intention to start flying suborbital vehicles, capable of transporting people to high altitudes out of any airport or launch site, on a commercial and regular basis. According to several studies, a market for suborbital "space tourism" exists. Another very promising application of suborbital flight is scientific research. The present paper provides an overview of the potential of commercial suborbital flight for science, including microgravity research. Suborbital flight provides a much-needed intermediate-duration opportunity between research performed in Earth orbit and more affordable but shorter duration alternatives, such as drop towers and zero-g parabolic flights. Moreover, suborbital flight will be less expensive and more frequent than both orbital flight and sounding rockets, and it has the capability to fly into sub-orbit the researcher together with the payload, and thus enable on-site interaction with the experiment. In the United States, both the National Aeronautics and Space Administration (NASA) and a number of private institutions have already shown interest in conducting scientific experiments, particularly microgravity research, aboard these new platforms. Researchers who intend to participate in future suborbital flights as payload specialists will need training, given the physical challenges posed by the flight. Finally, suborbital researchers may also want to have a basic knowledge of the legal status that will apply to them as passengers of such flights.

  7. Religion, spirituality and cardiovascular disease: research, clinical implications, and opportunities in Brazil.

    PubMed

    Lucchese, Fernando A; Koenig, Harold G

    2013-03-01

    In this paper we comprehensively review published quantitative research on the relationship between religion, spirituality (R/S), and cardiovascular (CV) disease, discuss mechanisms that help explain the associations reported, examine the clinical implications of those findings, and explore future research needed in Brazil on this topic. First, we define the terms religion, spirituality, and secular humanism. Next, we review research examining the relationships between R/S and CV risk factors (smoking, alcohol/drug use, physical inactivity, poor diet, cholesterol, obesity, diabetes, blood pressure, and psychosocial stress). We then review research on R/S, cardiovascular functions (CV reactivity, heart rate variability, etc.), and inflammatory markers (IL-6, IFN-γ, CRP, fibrinogen, IL-4, IL-10). Next we examine research on R/S and coronary artery disease, hypertension, stroke, dementia, cardiac surgery outcomes, and mortality (CV mortality in particular). We then discuss mechanisms that help explain these relationships (focusing on psychological, social, and behavioral pathways) and present a theoretical causal model based on a Western religious perspective. Next we discuss the clinical applications of the research, and make practical suggestions on how cardiologists and cardiac surgeons can sensitively and sensibly address spiritual issues in clinical practice. Finally, we explore opportunities for future research. No research on R/S and cardiovascular disease has yet been published from Brazil, despite the tremendous interest and involvement of the population in R/S, making this an area of almost unlimited possibilities for researchers in Brazil.

  8. Career advancement and educational opportunities: experiences and perceptions of internationally educated nurses.

    PubMed

    Salma, Jordana; Hegadoren, Kathleen M; Ogilvie, Linda

    2012-01-01

    The number of internationally educated nurses is increasing in the Canadian workforce. Recruitment of internationally educated nurses is often seen as a solution to ongoing nursing shortages. However, international recruitment needs to be accompanied by strategies to ensure long-term retention. One of the criteria for successful retention is the availability and accessibility of career advancement and educational opportunities. Little research exists on the opportunities for career advancement and education for internationally educated nurses in Canada. This interpretive descriptive study was conducted to look at the perceptions of internationally educated nurses regarding career advancement and educational opportunities in Alberta, Canada. Eleven internationally educated nurses, working as registered nurses in Alberta, were interviewed using semi-structured interviews. Five themes were identified: motherhood as a priority, communication and cultural challenges, process of skill recognition, perceptions of opportunity and need for mentorship.

  9. Equality of opportunities for next generation researchers: bridging the gap between theory and practice in Eastern Europe

    NASA Astrophysics Data System (ADS)

    Žagar, Nedjeljka; Alkauskas, Audrius; Gyürky, György; Heiri, Oliver; Robinson, Nathaniel D.; Schäfer, Thomas

    2016-04-01

    Twenty-five years after the fall of the Berlin wall and the historical opening of the European Union to the countries of Central and Eastern Europe, there is still a striking difference in the success of European countries in attracting research funds and talented researchers. A number of indicators document the differences in research success and research opportunities between Eastern and Western European countries, and even between Northern and Southern Europe. Differences, as described for example by a number of secured ERC grants, apply to all research fields and to researchers at all stages of their careers. While statistical analysis document large gradients in research performance across the continent, the underlying issues that young researchers struggle with are common across Europe, although they impact research environment to a different extent. These issues are presently being discussed within Sci-Generation, a COST Targeted Network that aims to enhance the European research environment for the next generation of young researchers. The major goal of the network is to contribute ideas towards overcoming these differences in opportunities across Europe. Targeting researchers in the early stage of their independent carrier or in the transition to independence, Sci-Generation is devoted to inclusiveness in order to represent a diversity of issues in science policy in Europe. In particular, the network's Working Group 1 focuses on the countries of Eastern and Southern Europe with less success in attracting European research funding. Among other issues, we considered the involvement of young researchers in decision-making processes at all levels important in order to increase the systems' transparency. As shown by an ongoing study of how language affects the evaluation of research applications, the use of the local language serves, in some cases, as one of the last stands of "science-managing elites" that grew up in systems before 1990. We discuss how a lack

  10. Identifying Opportunities for Decision Support Systems in Support of Regional Resource Use Planning: An Approach Through Soft Systems Methodology.

    PubMed

    Zhu; Dale

    2000-10-01

    / Regional resource use planning relies on key regional stakeholder groups using and having equitable access to appropriate social, economic, and environmental information and assessment tools. Decision support systems (DSS) can improve stakeholder access to such information and analysis tools. Regional resource use planning, however, is a complex process involving multiple issues, multiple assessment criteria, multiple stakeholders, and multiple values. There is a need for an approach to DSS development that can assist in understanding and modeling complex problem situations in regional resource use so that areas where DSSs could provide effective support can be identified, and the user requirements can be well established. This paper presents an approach based on the soft systems methodology for identifying DSS opportunities for regional resource use planning, taking the Central Highlands Region of Queensland, Australia, as a case study.

  11. Biogas Opportunities Roadmap Progress Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    In support of the Obama Administration's Climate Action Plan, the U.S. Department of Energy, the U.S. Environmental Protection Agency, and U.S. Department of Agriculture jointly released the Biogas Opportunities Roadmap Progress Report, updating the federal government's progress to reduce methane emissions through biogas systems since the Biogas Opportunities Roadmap was completed by the three agencies in July 2014. The report highlights actions taken, outlines challenges and opportunities, and identifies next steps to the growth of a robust biogas industry.

  12. New Webpage Brings Increased Visibility to Frederick National Laboratory Subcontracting Opportunities | Frederick National Laboratory for Cancer Research

    Cancer.gov

    A new webpage will now make it easier for small businesses and others to find and apply for Frederick National Laboratory for Cancer Research business opportunities. The new solicitations page, which launched on the Frederick National Lab website Aug

  13. Global report on preterm birth and stillbirth (5 of 7): advocacy barriers and opportunities.

    PubMed

    Sather, Megan; Fajon, Anne-Véronique; Zaentz, Rachel; Rubens, Craig E

    2010-02-23

    Efforts to achieve the Millennium Development Goals (MDGs) to improve maternal and child health can be accelerated by addressing preterm birth and stillbirth. However, most global health stakeholders are unaware of the inextricable connections of these adverse pregnancy outcomes to maternal, newborn and child health (MNCH). Improved visibility of preterm births and stillbirths will help fuel investments and strengthen commitments in the discovery, development and delivery of low-cost solutions globally. This article addresses potential barriers and opportunities to increasing global awareness and understanding. Qualitative research was conducted to analyze current knowledge, attitudes and commitments toward preterm birth and stillbirth; identify advocacy challenges; and learn more about examples of programs that successfully advocate for research and appropriate interventions. Forty-one individuals from 14 countries on six continents were interviewed. They included maternal, newborn, and child health advocates and implementers, United Nations agency representatives, policymakers, researchers, and private and government donors. A common recognition of three advocacy challenges with regard to preterm birth and stillbirth emerged from these interviews: (1) lack of data about the magnitude and impact; (2) lack of awareness and understanding; and (3) lack of low-cost, effective and scalable interventions. Participants also identified advocacy opportunities. The first of these opportunities involves linking preterm birth and stillbirth to the MDGs, adding these outcomes to broader global health discussions and advocacy efforts, and presenting a united voice among advocates in the context of broader MNCH issues when addressing preterm birth and stillbirth. Another key opportunity is putting a human face to these tragedies--such as a parent who can speak to the personal impact on the family. Lastly, several interviewees suggested identifying and engaging champions to

  14. Life Sciences Research and Development Opportunities During Suborbital Space Flight

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.

    2010-01-01

    Suborbital space platforms provide a unique opportunity for Space Life Sciences in the next few years. The opportunities include: physiological characterization of the first few minutes of space flight; evaluation of a wide-variety of medical conditions during periods of hyper and hypo-gravity through physiological monitoring; and evaluation of new biomedical and environmental health technologies under hyper and hypo-gravity conditions

  15. Virtual Reality Technologies for Research and Education in Obesity and Diabetes: Research Needs and Opportunities

    PubMed Central

    Ershow, Abby G; Peterson, Charles M; Riley, William T; Rizzo, Albert “Skip”; Wansink, Brian

    2011-01-01

    The rising rates, high prevalence, and adverse consequences of obesity and diabetes call for new approaches to the complex behaviors needed to prevent and manage these conditions. Virtual reality (VR) technologies, which provide controllable, multisensory, interactive three-dimensional (3D) stimulus environments, are a potentially valuable means of engaging patients in interventions that foster more healthful eating and physical activity patterns. Furthermore, the capacity of VR technologies to motivate, record, and measure human performance represents a novel and useful modality for conducting research. This article summarizes background information and discussions for a joint July 2010 National Institutes of Health – Department of Defense workshop entitled Virtual Reality Technologies for Research and Education in Obesity and Diabetes. The workshop explored the research potential of VR technologies as tools for behavioral and neuroscience studies in diabetes and obesity, and the practical potential of VR in fostering more effective utilization of diabetes- and obesity-related nutrition and lifestyle information. Virtual reality technologies were considered especially relevant for fostering desirable health-related behaviors through motivational reinforcement, personalized teaching approaches, and social networking. Virtual reality might also be a means of extending the availability and capacity of health care providers. Progress in the field will be enhanced by further developing available platforms and taking advantage of VR’s capabilities as a research tool for well-designed hypothesis-testing behavioral science. Multidisciplinary collaborations are needed between the technology industry and academia, and among researchers in biomedical, behavioral, pedagogical, and computer science disciplines. Research priorities and funding opportunities for use of VR to improve prevention and management of obesity and diabetes can be found at agency websites (National

  16. Virtual reality technologies for research and education in obesity and diabetes: research needs and opportunities.

    PubMed

    Ershow, Abby G; Peterson, Charles M; Riley, William T; Rizzo, Albert Skip; Wansink, Brian

    2011-03-01

    The rising rates, high prevalence, and adverse consequences of obesity and diabetes call for new approaches to the complex behaviors needed to prevent and manage these conditions. Virtual reality (VR) technologies, which provide controllable, multisensory, interactive three-dimensional (3D) stimulus environments, are a potentially valuable means of engaging patients in interventions that foster more healthful eating and physical activity patterns. Furthermore, the capacity of VR technologies to motivate, record, and measure human performance represents a novel and useful modality for conducting research. This article summarizes background information and discussions for a joint July 2010 National Institutes of Health - Department of Defense workshop entitled Virtual Reality Technologies for Research and Education in Obesity and Diabetes. The workshop explored the research potential of VR technologies as tools for behavioral and neuroscience studies in diabetes and obesity, and the practical potential of VR in fostering more effective utilization of diabetes- and obesity-related nutrition and lifestyle information. Virtual reality technologies were considered especially relevant for fostering desirable health-related behaviors through motivational reinforcement, personalized teaching approaches, and social networking. Virtual reality might also be a means of extending the availability and capacity of health care providers. Progress in the field will be enhanced by further developing available platforms and taking advantage of VR's capabilities as a research tool for well-designed hypothesis-testing behavioral science. Multidisciplinary collaborations are needed between the technology industry and academia, and among researchers in biomedical, behavioral, pedagogical, and computer science disciplines. Research priorities and funding opportunities for use of VR to improve prevention and management of obesity and diabetes can be found at agency websites (National

  17. Global Collaboration in Acute Care Clinical Research: Opportunities, Challenges, and Needs.

    PubMed

    Marshall, John C

    2017-02-01

    The most impactful research in critical care comes from trials groups led by clinician-investigators who study questions arising through the day-to-day care of critically ill patients. The success of this model reflects both "necessity"-the paucity of new therapies introduced through industry-led research-and "clinical reality"-nuanced modulation of standard practice can have substantial impact on clinically important outcomes. Success in a few countries has fueled efforts to build similar models around the world and to collaborate on an unprecedented scale in large international trials. International collaboration brings opportunity-the more rapid completion of clinical trials, enhanced generalizability of the results of these trials, and a focus on questions that have evoked international curiosity. It has changed practice, improved outcomes, and enabled an international response to pandemic threats. It also brings challenges. Investigators may feel threatened by the loss of autonomy inherent in collaboration, and appropriate models of academic credit are yet to be developed. Differences in culture, practice, ethical frameworks, research experience, and resource availability create additional imbalances. Patient and family engagement in research is variable and typically inadequate. Funders are poorly equipped to evaluate and fund international collaborative efforts. Yet despite or perhaps because of these challenges, the discipline of critical care is leading the world in crafting new models of clinical research collaboration that hold the promise of not only improving the care of the most vulnerable patients in the healthcare system but also transforming the way that we conduct clinical research.

  18. Research Ethics Review: Identifying Public Policy and Program Gaps

    PubMed Central

    Strosberg, Martin A.; Gefenas, Eugenijus; Famenka, Andrei

    2014-01-01

    We present an analytical frame-work for use by fellows of the Fogarty International Center–sponsored Advanced Certificate Program in Research Ethics for Central and Eastern Europe to identify gaps in the public policies establishing research ethics review systems that impede them from doing their job of protecting human research subjects. The framework, illustrated by examples from post-Communist countries, employs a logic model based on the public policy and public management literature. This paper is part of a collection of papers analyzing the Fogarty International Center’s International Research Ethics Education and Curriculum program. PMID:24782068

  19. Toward sustainable environmental quality: Identifying priority research questions for Latin America.

    PubMed

    Furley, Tatiana Heid; Brodeur, Julie; Silva de Assis, Helena C; Carriquiriborde, Pedro; Chagas, Katia R; Corrales, Jone; Denadai, Marina; Fuchs, Julio; Mascarenhas, Renata; Miglioranza, Karina Sb; Miguez Caramés, Diana Margarita; Navas, José Maria; Nugegoda, Dayanthi; Planes, Estela; Rodriguez-Jorquera, Ignacio Alejandro; Orozco-Medina, Martha; Boxall, Alistair Ba; Rudd, Murray A; Brooks, Bryan W

    2018-05-01

    The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research questions that would represent priority needs to address in the region. One hundred questions were received, then partitioned among categories, examined, and some rearranged during a workshop in Buenos Aires, Argentina. Twenty priority research questions were subsequently identified. These research questions included developing, improving, and harmonizing across LA countries methods for 1) identifying contaminants and degradation products in complex matrices (including biota); 2) advancing prediction of contaminant risks and effects in ecosystems, addressing lab-to-field extrapolation challenges, and understanding complexities of multiple stressors (including chemicals and climate change); and 3) improving management and regulatory tools toward achieving sustainable development. Whereas environmental contaminants frequently identified in these key questions were pesticides, pharmaceuticals, endocrine disruptors or modulators, plastics, and nanomaterials, commonly identified environmental challenges were related to agriculture, urban effluents, solid wastes, pulp and paper mills, and natural extraction activities. Several interesting research topics included assessing and preventing pollution impacts on conservation protected areas, integrating environment and health assessments, and developing strategies for identification, substitution, and design of less hazardous chemicals (e.g., green chemistry). Finally, a recurrent research need included developing an understanding of differential sensitivity of regional species and ecosystems to environmental contaminants and other stressors. Addressing these critical questions will

  20. Toward sustainable environmental quality: Identifying priority research questions for Latin America

    PubMed Central

    Furley, Tatiana Heid; Brodeur, Julie; Silva de Assis, Helena C; Carriquiriborde, Pedro; Chagas, Katia R; Corrales, Jone; Denadai, Marina; Fuchs, Julio; Mascarenhas, Renata; Miglioranza, Karina SB; Miguez Caramés, Diana Margarita; Navas, José Maria; Nugegoda, Dayanthi; Planes, Estela; Rodriguez‐Jorquera, Ignacio Alejandro; Orozco‐Medina, Martha; Boxall, Alistair BA; Rudd, Murray A

    2018-01-01

    ABSTRACT The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research questions that would represent priority needs to address in the region. One hundred questions were received, then partitioned among categories, examined, and some rearranged during a workshop in Buenos Aires, Argentina. Twenty priority research questions were subsequently identified. These research questions included developing, improving, and harmonizing across LA countries methods for 1) identifying contaminants and degradation products in complex matrices (including biota); 2) advancing prediction of contaminant risks and effects in ecosystems, addressing lab‐to‐field extrapolation challenges, and understanding complexities of multiple stressors (including chemicals and climate change); and 3) improving management and regulatory tools toward achieving sustainable development. Whereas environmental contaminants frequently identified in these key questions were pesticides, pharmaceuticals, endocrine disruptors or modulators, plastics, and nanomaterials, commonly identified environmental challenges were related to agriculture, urban effluents, solid wastes, pulp and paper mills, and natural extraction activities. Several interesting research topics included assessing and preventing pollution impacts on conservation protected areas, integrating environment and health assessments, and developing strategies for identification, substitution, and design of less hazardous chemicals (e.g., green chemistry). Finally, a recurrent research need included developing an understanding of differential sensitivity of regional species and ecosystems to environmental contaminants and other stressors. Addressing these critical

  1. Challenges and Opportunities: Recruitment and Retention of African Americans for Alzheimer's disease Research: Lessons Learned

    PubMed Central

    Ballard, Edna L.; Gwyther, Lisa P.; Edmonds, Henry L

    2013-01-01

    For more than three decades, recruitment and retention of African Americans for research in Alzheimer's disease have been regarded as difficult undertakings with poor results. The typical explanation for failure to respond to research participation options is widespread mistrust of research and the biomedical community. Mistrust is a reasonable response given the historical reality of malfeasance, victimization, and mistreatment over the course of the research participation history of African Americans. The challenges are real but there are opportunities for successful recruitment and retention of African Americans for research including research on Alzheimer's disease. Participation, however, comes with specific terms and considerations. Two of the most prominent criteria for research recruitment and retention are the transparency and accountability of the investigator which may determine how he or she proceeds from the start of the process throughout the steps of recruitment, retention and subsequent follow-up with the community. PMID:20711060

  2. 50 CFR 648.56 - Scallop research.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Scallop research. 648.56 Section 648.56... Scallop Fishery § 648.56 Scallop research. (a) At least biennially, in association with the biennial... Opportunity (FFO) that identifies research priorities for projects to be conducted by vessels using research...

  3. 50 CFR 648.56 - Scallop research.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Scallop research. 648.56 Section 648.56... Scallop Fishery § 648.56 Scallop research. (a) At least biennially, in association with the biennial... Opportunity (FFO) that identifies research priorities for projects to be conducted by vessels using research...

  4. 50 CFR 648.56 - Scallop research.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Scallop research. 648.56 Section 648.56... Scallop Fishery § 648.56 Scallop research. (a) At least biennially, in association with the biennial... Opportunity (FFO) that identifies research priorities for projects to be conducted by vessels using research...

  5. 50 CFR 648.56 - Scallop research.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Scallop research. 648.56 Section 648.56... Scallop Fishery § 648.56 Scallop research. (a) At least biennially, in association with the biennial... Opportunity (FFO) that identifies research priorities for projects to be conducted by vessels using research...

  6. Collaborative proposal on resilience : definitions, measurement, tools and research opportunities.

    DOT National Transportation Integrated Search

    2016-08-01

    Rutgers University Center for Advanced Infrastructure and Transportation (CAIT), in collaboration : with research partners within the University Transportation Center (UTC) consortium, seeks to identify : knowledge gaps and chart future R&D direction...

  7. Tracing Scientific Facilities through the Research Literature Using Persistent Identifiers

    NASA Astrophysics Data System (ADS)

    Mayernik, M. S.; Maull, K. E.

    2016-12-01

    Tracing persistent identifiers to their source publications is an easy task when authors use them, since it is a simple matter of matching the persistent identifier to the specific text string of the identifier. However, trying to understand if a publication uses the resource behind an identifier when such identifier is not referenced explicitly is a harder task. In this research, we explore the effectiveness of alternative strategies of associating publications with uses of the resource referenced by an identifier when it may not be explicit. This project is explored within the context of the NCAR supercomputer, where we are broadly interesting in the science that can be traced to the usage of the NCAR supercomputing facility, by way of the peer-reviewed research publications that utilize and reference it. In this project we explore several ways of drawing linkages between publications and the NCAR supercomputing resources. Identifying and compiling peer-reviewed publications related to NCAR supercomputer usage are explored via three sources: 1) User-supplied publications gathered through a community survey, 2) publications that were identified via manual searching of the Google scholar search index, and 3) publications associated with National Science Foundation (NSF) grants extracted from a public NSF database. These three sources represent three styles of collecting information about publications that likely imply usage of the NCAR supercomputing facilities. Each source has strengths and weaknesses, thus our discussion will explore how our publication identification and analysis methods vary in terms of accuracy, reliability, and effort. We will also discuss strategies for enabling more efficient tracing of research impacts of supercomputing facilities going forward through the assignment of a persistent web identifier to the NCAR supercomputer. While this solution has potential to greatly enhance our ability to trace the use of the facility through

  8. Novel target for high-risk neuroblastoma identified in pre-clinical research | Center for Cancer Research

    Cancer.gov

    Pre-clinical research by investigators at the Center for Cancer Research and their colleagues have identified a number of novel epigenetic targets for high-risk neuroblastoma and validated a promising new targeted inhibitor in pre-clinical models.  Read more...

  9. Characteristics of Exemplary Science, Technology, Engineering, and Math (STEM)-Related Experiential Learning Opportunities

    NASA Astrophysics Data System (ADS)

    Simmons, Jamie Munn

    Experiential opportunities at the secondary level give students the "intimate and necessary relation between the processes of actual experience and education" (Dewey, 1938, p. 19- 20). Career and Technical Education classes (CTE) and co-curricular experiences, one type of experiential learning, underpin and cultivate student curiosity and often channel interests into STEM-related post-secondary disciplines and career choices. There is little existent research on the characteristics of exemplary experiential learning opportunities and the impact on stakeholders. This study is intended to identify the qualities and characteristics of an exemplary secondary experience through the lived experiences of the stakeholders; students, STEM-related teachers, and CTE/STEM Administrators. A qualitative research design was used to examine characteristics and implications for students of four STEM-related programs throughout Virginia. Conclusions from the study include fundamental principles for providing exemplary experiential STEM-related learning opportunities. These principles include: providing hands-on, real world learning opportunities for students, providing learning opportunities that will enhance student ownership in their learning, providing unique and comprehensive career exploration opportunities for students, providing a schedule for teachers that will give them time to plan, deliver, and manage exemplary experiential learning opportunities, providing continual teacher and administrator in-service training relative to planning and implementing exemplary experiential learning opportunities, investing appropriate funds for providing exemplary experiential learning opportunities. Establishing and maintaining active partnerships with business/industry and colleges/universities, and maintaining active advisory communities, providing appropriate staff to support the provision of exemplary experiential learning opportunities is needed. The need for adequate funding

  10. Optimizing the User Experience: Identifying Opportunities to Improve Use of an Inpatient Portal.

    PubMed

    Walker, Daniel M; Menser, Terri; Yen, Po-Yin; McAlearney, Ann Scheck

    2018-01-01

    Patient portals specifically designed for the inpatient setting have significant potential to improve patient care. However, little is known about how the users of this technology, the patients, may interact with the inpatient portals. As a result, hospitals have limited ability to design approaches that support patient use of the portal. This study aims to evaluate the user experience associated with an inpatient portal. We used a Think-Aloud protocol to study user interactions with a commercially available inpatient portal-MyChart Bedside (MCB). Study participants included 19 English-speaking adults over the age of 18 years. In one-on-one sessions, participants narrated their experience using the MCB application and completing eight specific tasks. Recordings were transcribed and coded into three dimensions of the user experience: physical, cognitive, and sociobehavioral. Our analysis of the physical experience highlighted the navigational errors and technical challenges associated with the use of MCB. We also found that issues associated with the cognitive experience included comprehension problems that spurred anxiety and uncertainty. Analysis of the sociobehavioral experience suggested that users have different learning styles and preferences for learning including self-guided, handouts, and in-person training. Inpatient portals may be an effective tool to improve the patient experience in the hospital. Moreover, making this technology available to inpatients may help to foster ongoing use of technology across the care continuum. However, deriving the benefits from the technology requires appropriate support. We identified multiple opportunities for hospital management to intervene. In particular, teaching patients to use the application by making a variety of instructional materials available could help to reduce several identified barriers to use. Additionally, hospitals should be prepared to manage patient anxiety and increased questioning arising from the

  11. User-documented food consumption data from publicly available apps: an analysis of opportunities and challenges for nutrition research.

    PubMed

    Maringer, Marcus; Van't Veer, Pieter; Klepacz, Naomi; Verain, Muriel C D; Normann, Anne; Ekman, Suzanne; Timotijevic, Lada; Raats, Monique M; Geelen, Anouk

    2018-06-09

    The need for a better understanding of food consumption behaviour within its behavioural context has sparked the interest of nutrition researchers for user-documented food consumption data collected outside the research context using publicly available nutrition apps. The study aims to characterize the scientific, technical, legal and ethical features of this data in order to identify the opportunities and challenges associated with using this data for nutrition research. A search for apps collecting food consumption data was conducted in October 2016 against UK Google Play and iTunes storefronts. 176 apps were selected based on user ratings and English language support. Publicly available information from the app stores and app-related websites was investigated and relevant data extracted and summarized. Our focus was on characteristics related to scientific relevance, data management and legal and ethical governance of user-documented food consumption data. Food diaries are the most common form of data collection, allowing for multiple inputs including generic food items, packaged products, or images. Standards and procedures for compiling food databases used for estimating energy and nutrient intakes remain largely undisclosed. Food consumption data is interlinked with various types of contextual data related to behavioural motivation, physical activity, health, and fitness. While exchange of data between apps is common practise, the majority of apps lack technical documentation regarding data export. There is a similar lack of documentation regarding the implemented terms of use and privacy policies. While users are usually the owners of their data, vendors are granted irrevocable and royalty free licenses to commercially exploit the data. Due to its magnitude, diversity, and interconnectedness, user-documented food consumption data offers promising opportunities for a better understanding of habitual food consumption behaviour and its determinants. Non

  12. Airport surveys at travel destinations--underutilized opportunities in travel medicine research?

    PubMed

    Bauer, Irmgard L

    2015-01-01

    Research in destination airports, especially in resource-poor areas, allows unique immediate access to travelers at the conclusion of their trip. Response rates are high and the recall gap small. Trip-related health matters can be elicited relatively easily. An insight into travelers' decision-making processes on location would fill large gaps in our knowledge regarding travel health advice provision; yet, this approach is still much underutilized. Using PubMed, ScienceDirect, Google Scholar, and ProQuest, a review of the literature on airport surveys was conducted to determine where they were used, their response rates and purpose, and location-relevant methodological information. The lack of methodological guidelines in the reviewed literature resulted in recommendations for planning and conducting an airport survey at a destination airport. Millions of travelers in airports around the world represent an underutilized sample of potential study participants for topics that cannot be studied adequately in other settings. Benefiting from close cooperation between travel health professionals and airport authorities, researchers can expect not only large-scale convenience samples for surveys, but also opportunities to explore exciting and creative research topics to broaden our understanding of travel medicine and health. © 2014 International Society of Travel Medicine.

  13. The Community Mentorship Program: Providing Community-Engagement Opportunities for Early-Stage Clinical and Translational Scientists to Facilitate Research Translation

    PubMed Central

    Patino, Cecilia M.; Kubicek, Katrina; Robles, Marisela; Kiger, Holly; Dzekov, Jeanne

    2016-01-01

    Problem A goal of the Southern California Clinical and Translational Science Institute (SC-CTSI) at the University of Southern California (USC) and Children's Hospital Los Angeles is to train early-stage clinical translational scientists (CTSs) to conduct research that improves the health of diverse communities. This goal aligns well with the Institute of Medicine's recommendations emphasizing community engagement in biomedical research that facilitates research translation. The Community Mentorship Program (CMP), created to complement community-engaged research (CER) didactics, matches CTSs with community mentors who help CTSs identify and complete community-engaged experiences that inform their research. Approach The CMP was piloted in 2013-2015 by the SC-CTSI Workforce Development and Community-Engagement cores. The CMP team matched three CTSs (assistant professors pursuing mentored career development awards, two with CER experience) with mentors at community-based organizations (CBOs) aligned with their research interests. Each mentor–mentee pair signed a memorandum of understanding. The CMP team checked in regularly, monitoring progress and addressing challenges in CTSs’ completion of their community-engaged experience. Outcomes All pairs completed at least one community-engaged activity informing the CTS's research. In exit interviews, the CTSs and CBO mentors expressed satisfaction with the program and stated they would continue to work together. The CTSs reported the program provided opportunities to develop networks outside academia, build trust within the community, and receive feedback and learn from individuals in communities affected by their research. Next Steps The CMP will be expanded to include all eligible early-career CTSs and promoted for use in similar settings outside the SC-CTSI. PMID:27508342

  14. The Community Mentorship Program: Providing Community-Engagement Opportunities for Early-Stage Clinical and Translational Scientists to Facilitate Research Translation.

    PubMed

    Patino, Cecilia M; Kubicek, Katrina; Robles, Marisela; Kiger, Holly; Dzekov, Jeanne

    2017-02-01

    A goal of the Southern California Clinical and Translational Science Institute (SC-CTSI) at the University of Southern California and Children's Hospital Los Angeles is to train early-stage clinical and translational scientists (CTSs) to conduct research that improves the health of diverse communities. This goal aligns well with the Institute of Medicine's recommendations emphasizing community engagement in biomedical research that facilitates research translation. The Community Mentorship Program (CMP), created to complement community-engaged research didactics, matches CTSs with community mentors who help them identify and complete community-engaged experiences that inform their research. The CMP was piloted in 2013-2015 by the SC-CTSI Workforce Development and Community Engagement cores. The CMP team matched three CTSs (assistant professors pursuing mentored career development awards) with mentors at community-based organizations (CBOs) aligned with their research interests. Each mentor-mentee pair signed a memorandum of understanding. The CMP team checked in regularly, monitoring progress and addressing challenges in CTSs' completion of their community-engaged experience. Each pair completed at least one community-engaged activity informing the CTS's research. In exit interviews, the CTSs and CBO mentors expressed satisfaction with the program and stated that they would continue to work together. The CTSs reported that the program provided opportunities to develop networks outside academia, build trust within the community, and receive feedback and learn from individuals in communities affected by their research. The CMP will be expanded to include all eligible early-career CTSs and promoted for use in similar settings outside the SC-CTSI.

  15. Energy Savings Potential and RD&D Opportunities for Commercial Building Appliances (2015 Update)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goetzler, William; Guernsey, Matt; Foley, Kevin

    The Department of Energy commissioned a technology characterization and assessment of appliances used in commercial buildings for cooking, cleaning, water heating, and other end-uses. The primary objectives of this study were to document the energy consumed by commercial appliances and identify research, development, and demonstration opportunities to improve energy efficiency in each end-use. This report serves as an update to a 2009 report of the same name by incorporating updated data and sources where possible and updating the available technology options that provide opportunities for efficiency improvements.

  16. Big data in healthcare - the promises, challenges and opportunities from a research perspective: A case study with a model database.

    PubMed

    Adibuzzaman, Mohammad; DeLaurentis, Poching; Hill, Jennifer; Benneyworth, Brian D

    2017-01-01

    Recent advances in data collection during routine health care in the form of Electronic Health Records (EHR), medical device data (e.g., infusion pump informatics, physiological monitoring data, and insurance claims data, among others, as well as biological and experimental data, have created tremendous opportunities for biological discoveries for clinical application. However, even with all the advancement in technologies and their promises for discoveries, very few research findings have been translated to clinical knowledge, or more importantly, to clinical practice. In this paper, we identify and present the initial work addressing the relevant challenges in three broad categories: data, accessibility, and translation. These issues are discussed in the context of a widely used detailed database from an intensive care unit, Medical Information Mart for Intensive Care (MIMIC III) database.

  17. Biowaste biorefinery in Europe: opportunities and research & development needs.

    PubMed

    Fava, Fabio; Totaro, Grazia; Diels, Ludo; Reis, Maria; Duarte, Jose; Carioca, Osvaldo Beserra; Poggi-Varaldo, Héctor M; Ferreira, Bruno Sommer

    2015-01-25

    This review aims to explore the needs and opportunities of research & development in the field of biowaste biorefinery in Europe. Modern industry in recent years is giving its close attention on organic waste as a new precious bioresource. Specific biowaste valorisation pathways are focusing on food processing waste, being food sector the first manufacture in Europe. Anyway they need to be further tested and validated and then transferred at the larger scale. In particular, they also need to become integrated, combining biomass pretreatments and recovery of biogenic chemicals with bioconversion processes in order to obtain a large class of chemicals. This will help to (a) use the whole biowaste, by avoiding producing residues and providing to the approach the required environmental sustainability, and (b) producing different biobased products that enter different markets, to get the possible economical sustainability of the whole biorefinery. However, the costs of the developed integrated processes might be high, mostly for the fact that the industry dealing with such issues is still underdeveloped and therefore dominated by high processing costs. Such costs can be significantly reduced by intensifying research & development on process integration and intensification. The low or no cost of starting material along with the environmental benefits coming from the concomitant biowaste disposal would offset the high capital costs for initiating such a biorefinery. As long as the oil prices tend to increase (and they will) this strategy will become even more attractive. Copyright © 2013 Elsevier B.V. All rights reserved.

  18. STEM Faculty as Learners in Pedagogical Reform and the Role of Research Articles as Professional Development Opportunities

    ERIC Educational Resources Information Center

    Mulnix, Amy B.

    2016-01-01

    Discipline-based education research (DBER) publications are opportunities for professional development around science, technology, engineering, and mathematics (STEM) education reform. Learning theory tells us these publications could be more impactful if authors, reviewers, and editors pay greater attention to linking principles and practice.…

  19. Mapping human dimensions of climate change research in the Canadian Arctic.

    PubMed

    Ford, James D; Bolton, Kenyon; Shirley, Jamal; Pearce, Tristan; Tremblay, Martin; Westlake, Michael

    2012-12-01

    This study maps current understanding and research trends on the human dimensions of climate change (HDCC) in the eastern and central Canadian Arctic. Developing a systematic literature review methodology, 117 peer reviewed articles are identified and examined using quantitative and qualitative methods. The research highlights the rapid expansion of HDCC studies over the last decade. Early scholarship was dominated by work documenting Inuit observations of climate change, with research employing vulnerability concepts and terminology now common. Adaptation studies which seek to identify and evaluate opportunities to reduce vulnerability to climate change and take advantage of new opportunities remain in their infancy. Over the last 5 years there has been an increase social science-led research, with many studies employing key principles of community-based research. We currently have baseline understanding of climate change impacts, adaptation, and vulnerability in the region, but key gaps are evident. Future research needs to target significant geographic disparities in understanding, consider risks and opportunities posed by climate change outside of the subsistence hunting sector, complement case study research with regional analyses, and focus on identifying and characterizing sustainable and feasible adaptation interventions.

  20. New opportunities for field research on the pathogenesis and treatment of Lassa fever.

    PubMed

    Khan, Sheik Humarr; Goba, Augustine; Chu, May; Roth, Cathy; Healing, Tim; Marx, Arthur; Fair, Joseph; Guttieri, Mary C; Ferro, Philip; Imes, Tiffany; Monagin, Corina; Garry, Robert F; Bausch, Daniel G

    2008-04-01

    Unlike many viral hemorrhagic fevers (VHFs), Lassa fever (LF) is not a rare disease that emerges only as sporadic cases or in outbreak form. Although surveillance is inadequate to determine the true incidence, up to 300,000 infections and 5000 deaths from LF are estimated to occur yearly. The highest incidence is in the "Mano River Union (MRU) countries" of Sierra Leone, Liberia, and Guinea. Although civil unrest in this region over the past two decades has impeded capacity building and research, new-found peace in recent years presents new opportunities. In 2004, the Mano River Union Lassa Fever Network (MRU LFN) was established to assist MRU countries in the development of national and regional surveillance, diagnosis, treatment, control, and prevention of LF. Here, we review the present literature on treatment and pathogenesis of LF and outline priorities for future research in the field made possible by the improved research capacity of the MRU LFN.

  1. Providing Undergraduate Research Opportunities Through the World Rivers Observatory Collaborative Network

    NASA Astrophysics Data System (ADS)

    Gillies, S. L.; Marsh, S. J.; Janmaat, A.; Peucker-Ehrenbrink, B.; Voss, B.; Holmes, R. M.

    2013-12-01

    Successful research collaboration exists between the University of the Fraser Valley (UFV), a primarily undergraduate-serving university located on the Fraser River in British Columbia, and the World Rivers Observatory that is coordinated through the Woods Hole Oceanographic Institution (WHOI) and the Woods Hole Research Center (WHRC). The World Rivers Observatory coordinates time-series sampling of 15 large rivers, with particular focus on the large Arctic rivers, the Ganges-Brahmaputra, Congo, Fraser, Yangtze (Changjiang), Amazon, and Mackenzie River systems. The success of this international observatory critically depends on the participation of local collaborators, such as UFV, that are necessary in order to collect temporally resolved data from these rivers. Several faculty members and undergraduate students from the Biology and Geography Departments of UFV received on-site training from the lead-PIs of the Global Rivers Observatory. To share information and ensure good quality control of sampling methods, WHOI and WHRC hosted two international workshops at Woods Hole for collaborators. For the past four years, faculty and students from UFV have been collecting a variety of bi-monthly water samples from the Fraser River for the World Rivers Observatory. UFV undergraduate students who become involved learn proper sampling techniques and are given the opportunity to design and conduct their own research. Students have collected, analyzed and presented data from this project at regional, national, and international scientific meetings. UFV undergraduate students have also been hosted by WHOI and WHRC as guest students to work on independent research projects. While at WHOI and WHRC, students are able to conduct research using state-of-the-art specialized research facilities not available at UFV.

  2. Aerospace Measurements: Challenges and Opportunities

    NASA Technical Reports Server (NTRS)

    Conway, Bruce A.

    1992-01-01

    New aerospace research initiatives offer both challenges and opportunities to rapidly-emerging electronics and electro-optics technology. Defining and implementing appropriate measurement technology development programs in response to the aeronautical ground facility research and testing needs of the new initiatives poses some particularly important problems. This paper discusses today's measurement challenges along with some of the technological opportunities which offer some hope for meeting the challenges, and describes measurement technology activities currently underway in the Langley Research Center's Instrument Research Division to address modern aerospace research and design engineering requirements. Projected and realized benefits and payoffs from the ongoing measurement and instrumentation efforts will be emphasized. A discussion of future trends in the aerospace measurement technology field will be included.

  3. Informed Consent in Implantable BCI Research: Identifying Risks and Exploring Meaning.

    PubMed

    Klein, Eran

    2016-10-01

    Implantable brain-computer interface (BCI) technology is an expanding area of engineering research now moving into clinical application. Ensuring meaningful informed consent in implantable BCI research is an ethical imperative. The emerging and rapidly evolving nature of implantable BCI research makes identification of risks, a critical component of informed consent, a challenge. In this paper, 6 core risk domains relevant to implantable BCI research are identified-short and long term safety, cognitive and communicative impairment, inappropriate expectations, involuntariness, affective impairment, and privacy and security. Work in deep brain stimulation provides a useful starting point for understanding this core set of risks in implantable BCI. Three further risk domains-risks pertaining to identity, agency, and stigma-are identified. These risks are not typically part of formalized consent processes. It is important as informed consent practices are further developed for implantable BCI research that attention be paid not just to disclosing core research risks but exploring the meaning of BCI research with potential participants.

  4. Assessing the uptake of persistent identifiers by research infrastructure users

    PubMed Central

    Maull, Keith E.

    2017-01-01

    Significant progress has been made in the past few years in the development of recommendations, policies, and procedures for creating and promoting citations to data sets, software, and other research infrastructures like computing facilities. Open questions remain, however, about the extent to which referencing practices of authors of scholarly publications are changing in ways desired by these initiatives. This paper uses four focused case studies to evaluate whether research infrastructures are being increasingly identified and referenced in the research literature via persistent citable identifiers. The findings of the case studies show that references to such resources are increasing, but that the patterns of these increases are variable. In addition, the study suggests that citation practices for data sets may change more slowly than citation practices for software and research facilities, due to the inertia of existing practices for referencing the use of data. Similarly, existing practices for acknowledging computing support may slow the adoption of formal citations for computing resources. PMID:28394907

  5. Research objectives, opportunities, and facilities for microgravity science

    NASA Technical Reports Server (NTRS)

    Bayuzick, Robert J.

    1992-01-01

    Microgravity Science in the U.S.A. involves research in fluids science, combustion science, materials science, biotechnology, and fundamental physics. The purpose is to achieve a thorough understanding of the effects of gravitational body forces on physical phenomena relevant to those disciplines. This includes the study of phenomena which are usually overwhelmed by the presence of gravitational body forces and, therefore, chiefly manifested when gravitational forces are weak. In the pragmatic sense, the research involves gravity level as an experimental parameter. Calendar year 1992 is a landmark year for research opportunities in low earth orbit for Microgravity Science. For the first time ever, three Spacelab flights will fly in a single year: IML-1 was launched on January 22; USML-1 was launched on June 25; and, in September, SL-J will be launched. A separate flight involving two cargo bay carriers, USMP-1, will be launched in October. From the beginning of 1993 up to and including the Space Station era (1997), nine flights involving either Spacelab or USMP carriers will be flown. This will be augmented by a number of middeck payloads and get away specials flying on various flights. All of this activity sets the stage for experimentation on Space Station Freedom. Beginning in 1997, experiments in Microgravity Science will be conducted on the Space Station. Facilities for doing experiments in protein crystal growth, solidification, and biotechnology will all be available. These will be joined by middeck-class payloads and the microgravity glove box for conducting additional experiments. In 1998, a new generation protein crystal growth facility and a facility for conducting combustion research will arrive. A fluids science facility and additional capability for conducting research in solidification, as well as an ability to handle small payloads on a quick response basis, will be added in 1999. The year 2000 will see upgrades in the protein crystal growth and

  6. Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.

    PubMed

    Yuen, Lik Hang; Franzini, Raphael M

    2017-05-04

    DNA-encoded chemical libraries (DECLs) are pools of DNA-tagged small molecules that enable facile screening and identification of bio-macromolecule binders. The successful development of DECLs has led to their increasingly important role in drug development, and screening hits have entered clinical trials. In this review, we summarize the development and currently active research areas of DECLs with a focus on contributions from groups at academic institutes. We further look at opportunities and future directions of DECL research in medicinal chemistry and chemical biology based on the symbiotic relationship between academia and industry. Challenges associated with the application of DECLs in academic drug discovery are further discussed. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. The resident scholar program: a research training opportunity for internal medicine house staff.

    PubMed

    Byrnes, Abigail B; McCormack, Francis X; Diers, Tiffiny; Jazieh, Abdul-Rahman

    2007-01-01

    Housestaff research training is a challenging task that is complicated by the lack of a structured process and dedicated time. The Resident Scholar Program (RSP) at the University of Cincinnati, Department of Internal Medicine was created to overcome these challenges. Interested internal medicine house staff are required to submit an application to the residency research director including a project description signed by a faculty mentor. If the project is approved, a 4-month elective rotation is scheduled for the following year. Residents spend the first month on a consult service in the subspecialty area of their research and the remaining 3 months performing their research project. The RSP was launched in July 2003. The percentage of residents participating in research more than tripled. The subspecialty areas represented by RSP research were more diverse than those represented in prior years. Most participants participated in clinical research projects (84%), with 63% of projects being prospective in design. The RSP residents were twice as likely to obtain subspecialty fellowship positions compared to non-RSP residents (89% vs 46%, respectively). The RSP enables house staff to participate in research opportunities in their areas of interest. Development of a more systematic assessment method to study the impact of the program is underway, but the high participation rate reflects resident interest in such a program, particularly for residents with aspirations in pursuing fellowship training.

  8. Researchers identify potential therapeutic targets for a rare childhood cancer | Center for Cancer Research

    Cancer.gov

    CCR researchers have identified the mechanism behind a rare but extremely aggressive childhood cancer called alveolar rhabdomyosarcoma (ARMS) and have pinpointed a potential drug target for its treatment. Learn more...

  9. Youth Internet use: risks and opportunities.

    PubMed

    Guan, Shu-Sha Angie; Subrahmanyam, Kaveri

    2009-07-01

    The Internet has become all pervasive in the lives of young people and this paper will review studies that examine the risks and opportunities that it affords. We will examine research that investigates the more negative aspects of youth online behavior such as addiction as well as online risks such as harassment/cyber bullying and sexual solicitation. In addition, positive aspects of Internet use such as its potential for learning and enhancing social relations as well as delivering health interventions will be examined. The results show that online risks such as addiction, cyber bullying, and sexual solicitation are associated with negative consequences for youth. It is important to note that not all children are equally susceptible and more research is necessary to identify the youth most at risk as well as to develop effective interventions. The Internet can also provide benefits in the areas of cognitive, social, and physical development, and can also be used to deliver treatment interventions. The Internet represents both risks and opportunities for young people. To protect youth who are at risk for online addiction, bullying, and solicitation, we need more research to understand which youth may be most susceptible and to develop targeted interventions to protect them. The Internet also has many positive aspects and can be used to enhance youth learning and empowerment; although it is a tremendous health resource and can be used to cheaply deliver interventions, we need to understand how to better implement them to enhance their effectiveness.

  10. Enhancing dermatology education: resident presentation opportunities.

    PubMed

    Park, Kelly K

    2015-09-01

    Dermatology residency is a time to maximize educational experiences, which include opportunities to attend academic meetings and present research and clinical cases. In this article, resident presentation opportunities at major academic dermatology meetings are reviewed.

  11. Small Business Innovation Research GRC Phase I, Phase II, and Post-Phase II Opportunity Assessment for 2015

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung D.; Steele, Gynelle C.

    2016-01-01

    This report outlines the 2015 Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) Phase I, Phase II, and Post-Phase II opportunity contract award results associated with NASA's Aeronautics Research Mission Directorate (ARMD), Human Exploration and Operations Mission Directorate (HEOMD), Science Mission Directorate (SMD), and Space Technology Mission Directorate (STMD) for NASA Glenn Research Center. The report also highlights the number of Phase I, Phase II, and Post-Phase II contracts awarded by mission directorate. The 2015 Phase I contract awards to companies in Ohio and their corresponding technologies are also discussed.

  12. The recreation opportunity spectrum: a framework for planning, management, and research.

    Treesearch

    Roger N. Clark; George H. Stankey

    1979-01-01

    The end product of recreation management is a diverse range of opportunities from which people can derive various experiences. This paper offers a framework for managing recreation opportunities based on six physical, biological, social, and managerial factors that, when combined, can be utilized by recreationists to obtain diverse experiences.

  13. Genomics pipelines and data integration: challenges and opportunities in the research setting.

    PubMed

    Davis-Turak, Jeremy; Courtney, Sean M; Hazard, E Starr; Glen, W Bailey; da Silveira, Willian A; Wesselman, Timothy; Harbin, Larry P; Wolf, Bethany J; Chung, Dongjun; Hardiman, Gary

    2017-03-01

    The emergence and mass utilization of high-throughput (HT) technologies, including sequencing technologies (genomics) and mass spectrometry (proteomics, metabolomics, lipids), has allowed geneticists, biologists, and biostatisticians to bridge the gap between genotype and phenotype on a massive scale. These new technologies have brought rapid advances in our understanding of cell biology, evolutionary history, microbial environments, and are increasingly providing new insights and applications towards clinical care and personalized medicine. Areas covered: The very success of this industry also translates into daunting big data challenges for researchers and institutions that extend beyond the traditional academic focus of algorithms and tools. The main obstacles revolve around analysis provenance, data management of massive datasets, ease of use of software, interpretability and reproducibility of results. Expert commentary: The authors review the challenges associated with implementing bioinformatics best practices in a large-scale setting, and highlight the opportunity for establishing bioinformatics pipelines that incorporate data tracking and auditing, enabling greater consistency and reproducibility for basic research, translational or clinical settings.

  14. Workshop on Energy Research Opportunities for Physics Graduates & Postdocs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kate Kirby

    Young people these days are very concerned about the environment. There is also a great deal of interest in using technology to improve energy efficiency. Many physics students share these concerns and would like to find ways to use their scientific and quantitative skills to help overcome the environmental challenges that the world faces. This may be particularly true for female students. Showing physics students how they can contribute to environmental and energy solutions while doing scientific research which excites them is expected to attract more physicists to work on these very important problems and to retain more of themore » best and the brightest in physical science. This is a major thrust of the 'Gathering Storm' report, the 'American Competitiveness Initiative' report, and several other studies. With these concerns in mind, the American Physical Society (APS) and more specifically, the newly formed APS Topical Group on Energy Research and Applications (GERA), organized and conducted a one-day workshop for graduate students and post docs highlighting the contributions that physics-related research can make to meeting the nation's energy needs in environmentally friendly ways. A workshop program committee was formed and met four times by conference call to determine session topics and to suggest appropriate presenters for each topic. Speakers were chosen not only for their prominence in their respective fields of energy research but also for their ability to relate their work to young people. The workshop was held the day before the APS March Meeting on March 14, 2009 in Portland, OR. The workshop was restricted to approximately 80 young physicists to encourage group discussion. Talks were planned and presented at a level of participants with a physics background but no special knowledge of energy research. Speakers were asked to give a broad overview of their area of research before talking more specifically about their own work. The format was

  15. Opportunities in biotechnology.

    PubMed

    Gartland, Kevan M A; Gartland, Jill S

    2018-06-08

    Strategies for biotechnology must take account of opportunities for research, innovation and business growth. At a regional level, public-private collaborations provide potential for such growth and the creation of centres of excellence. By considering recent progress in areas such as genomics, healthcare diagnostics, synthetic biology, gene editing and bio-digital technologies, opportunities for smart, strategic and specialised investment are discussed. These opportunities often involve convergent or disruptive technologies, combining for example elements of pharma-science, molecular biology, bioinformatics and novel device development to enhance biotechnology and the life sciences. Analytical applications use novel devices in mobile health, predictive diagnostics and stratified medicine. Synthetic biology provides opportunities for new product development and increased efficiency for existing processes. Successful centres of excellence should promote public-private business partnerships, clustering and global collaborations based on excellence, smart strategies and innovation if they are to remain sustainable in the longer term. Copyright © 2018. Published by Elsevier B.V.

  16. [Factors influencing research activity of Andalusian nurses and improvement strategies].

    PubMed

    López Alonso, Sergio R; Gálvez González, María; Amezcua, Manuel

    2013-04-01

    To identify factors influencing research activity of Andalusian nurses and to find improvement strategies. Qualitative research using SWOT analysis (weaknesses, threats, strengths, opportunities). Nurses were selected deliberately in eight groups according to predetermined criteria. Analysis included categorization and relationship of factors and strategies. 81 participants were included in groups of 7-12 range. 45 categories were identified with 212 factors: 12 weaknesses (50 factors), 10 strengths (44 factors), 12 threats (68 factors) and 11 opportunities (50 factors). In addition, 32 categories were identified with 53 strategies: 14 categories of W-T strategies (42 strategies), 3 categories of S-T strategies (11 strategies), 5 categories of W-O strategies (13 strategies) and 10 categories of S-O strategies (41 strategies). Nurses identified numerous factors, mainly threats. The strategies are focused on W-T but they also suggest many but weak 5-0 strategies due to the low potential of the opportunities and strengths perceived.

  17. Children as Researchers: What We Can Learn from Them about the Impact of Poverty on Literacy Opportunities?

    ERIC Educational Resources Information Center

    Kellett, Mary

    2009-01-01

    This paper challenges some of the assumptions about our understanding of and approaches to literacy. Crucially, it provides evidence hitherto missing from the body of research knowledge: children's own perspectives on literacy opportunities accessed by children themselves. Reading proficiency is pivotal in education, providing a platform on which…

  18. Anaerobic digestion of microalgal biomass: Challenges, opportunities and research needs.

    PubMed

    Gonzalez-Fernandez, Cristina; Sialve, Bruno; Molinuevo-Salces, Beatriz

    2015-12-01

    Integration of anaerobic digestion (AD) with microalgae processes has become a key topic to support economic and environmental development of this resource. Compared with other substrates, microalgae can be produced close to the plant without the need for arable lands and be fully integrated within a biorefinery. As a limiting step, anaerobic hydrolysis appears to be one of the most challenging steps to reach a positive economic balance and to completely exploit the potential of microalgae for biogas and fertilizers production. This review covers recent investigations dealing with microalgae AD and highlights research opportunities and needs to support the development of this resource. Novel approaches to increase hydrolysis rate, the importance of the reactor design and the noteworthiness of the microbial anaerobic community are addressed. Finally, the integration of AD with microalgae processes and the potential of the carboxylate platform for chemicals and biofuels production are reviewed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Using strategic foresight to assess conservation opportunity.

    PubMed

    Cook, Carly N; Wintle, Bonnie C; Aldrich, Stephen C; Wintle, Brendan A

    2014-12-01

    The nature of conservation challenges can foster a reactive, rather than proactive approach to decision making. Failure to anticipate problems before they escalate results in the need for more costly and time-consuming solutions. Proactive conservation requires forward-looking approaches to decision making that consider possible futures without being overly constrained by the past. Strategic foresight provides a structured process for considering the most desirable future and for mapping the most efficient and effective approaches to promoting that future with tools that facilitate creative thinking. The process involves 6 steps: setting the scope, collecting inputs, analyzing signals, interpreting the information, determining how to act, and implementing the outcomes. Strategic foresight is ideal for seeking, recognizing, and realizing conservation opportunities because it explicitly encourages a broad-minded, forward-looking perspective on an issue. Despite its potential value, the foresight process is rarely used to address conservation issues, and previous attempts have generally failed to influence policy. We present the strategic foresight process as it can be used for proactive conservation planning, describing some of the key tools in the foresight tool kit and how they can be used to identify and exploit different types of conservation opportunities. Scanning is an important tool for collecting and organizing diverse streams of information and can be used to recognize new opportunities and those that could be created. Scenario planning explores how current trends, drivers of change, and key uncertainties might influence the future and can be used to identify barriers to opportunities. Backcasting is used to map out a path to a goal and can determine how to remove barriers to opportunities. We highlight how the foresight process was used to identify conservation opportunities during the development of a strategic plan to address climate change in New York

  20. Technology in Parkinson disease: Challenges and Opportunities

    PubMed Central

    Espay, Alberto J.; Bonato, Paolo; Nahab, Fatta; Maetzler, Walter; Dean, John M.; Klucken, Jochen; Eskofier, Bjoern M.; Merola, Aristide; Horak, Fay; Lang, Anthony E.; Reilmann, Ralf; Giuffrida, Joe; Nieuwboer, Alice; Horne, Malcolm; Little, Max A.; Litvan, Irene; Simuni, Tanya; Dorsey, E. Ray; Burack, Michelle A.; Kubota, Ken; Kamondi, Anita; Godinho, Catarina; Daneault, Jean-Francois; Mitsi, Georgia; Krinke, Lothar; Hausdorff, Jeffery M.; Bloem, Bastiaan R.; Papapetropoulos, Spyros

    2016-01-01

    The miniaturization, sophistication, proliferation, and accessibility of technologies are enabling the capturing of more and previously inaccessible phenomena in Parkinson disease (PD). However, more information has not translated into greater understanding of disease complexity to satisfy diagnostic and therapeutic needs. Challenges include non-compatible technology platforms, the need for wide-scale and long-term deployment of sensor technology (in particular among vulnerable elderly patients), and the gap between the “big data” acquired with sensitive measurement technologies and their limited clinical application. Major opportunities could be realized if new technologies are developed as part of open-source and/or open-hardware platforms enabling multi-channel data capture, sensitive to the broad range of motor and non-motor problems that characterize PD, and adaptable into self-adjusting, individualized treatment delivery systems. The International Parkinson and Movement Disorders Society Task Force on Technology is entrusted to convene engineers, clinicians, researchers, and patients to promote the development of integrated measurement and closed-loop therapeutic systems with high patient adherence that also serve to: 1) encourage the adoption of clinico-pathophysiologic phenotyping and early detection of critical disease milestones; 2) enhance tailoring of symptomatic therapy; 3) improve subgroup targeting of patients for future testing of disease modifying treatments; and 4) identify objective biomarkers to improve longitudinal tracking of impairments in clinical care and research. This article summarizes the work carried out by the Task Force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and quality of life of individuals with PD. PMID:27125836

  1. Crowdsourcing in biomedicine: challenges and opportunities

    PubMed Central

    Khare, Ritu; Good, Benjamin M.; Leaman, Robert; Su, Andrew I.

    2016-01-01

    The use of crowdsourcing to solve important but complex problems in biomedical and clinical sciences is growing and encompasses a wide variety of approaches. The crowd is diverse and includes online marketplace workers, health information seekers, science enthusiasts and domain experts. In this article, we review and highlight recent studies that use crowdsourcing to advance biomedicine. We classify these studies into two broad categories: (i) mining big data generated from a crowd (e.g. search logs) and (ii) active crowdsourcing via specific technical platforms, e.g. labor markets, wikis, scientific games and community challenges. Through describing each study in detail, we demonstrate the applicability of different methods in a variety of domains in biomedical research, including genomics, biocuration and clinical research. Furthermore, we discuss and highlight the strengths and limitations of different crowdsourcing platforms. Finally, we identify important emerging trends, opportunities and remaining challenges for future crowdsourcing research in biomedicine. PMID:25888696

  2. Environmental pollutants, diet, physical activity, body size, and breast cancer: where do we stand in research to identify opportunities for prevention?

    PubMed

    Brody, Julia Green; Rudel, Ruthann A; Michels, Karin B; Moysich, Kirsten B; Bernstein, Leslie; Attfield, Kathleen R; Gray, Sharon

    2007-06-15

    Breast cancer is the most common invasive cancer in women worldwide and the leading cause of death in US women in mid-life. Treatment has adverse effects, adding to the importance of finding modifiable risk factors. At the invitation of Susan G. Komen for the Cure, we reviewed studies of breast cancer and environmental pollutants, diet (assessed prospectively), body size, and physical activity, and animal studies that identify chemicals as potential mammary carcinogens. Databases developed in the review include information on 216 chemicals that increased mammary gland tumors in animal studies and 450 epidemiologic studies (accessible at www.silentspring.org/sciencereview and www.komen.org/environment). Exposure to potential mammary carcinogens is widespread from chemicals found in consumer products, air and drinking water pollution, food, and women's workplaces. Epidemiologic studies have included only a small number of chemicals identified as mammary carcinogens or as hormone disruptors, which may have implications for breast cancer; however, evidence is emerging for associations between breast cancer and polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and organic solvents. Prospective diet studies have not revealed consistent associations with breast cancer. Improved exposure assessment methods will help advance future human studies of both diet and environmental pollutants. Studies of physical activity show that it is protective. In the same vein as evidence-based medicine, messages for patients, policymakers, and the public should support decision-making based on the strength of current evidence; such messages might address exposure reduction for some pollutants. Investments in research on environmental factors in breast cancer have potentially large public health benefits.

  3. Maine DOT Research Peer Exchange : June 13-15, 2017

    DOT National Transportation Integrated Search

    2017-10-13

    On June 13 15, 2017 the Maine Department of Transportation hosted a research peer exchange to promote the research program within the department, provide a mechanism for sharing research management ideas amongst the team members, identify opportun...

  4. Mathematics and biology: The interface, challenges and opportunities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levin, S.A.

    1992-06-01

    The interface between mathematics and biology has long been a rich area of research, with mutual benefit to each supporting discipline. Traditional areas of investigation, such as population genetics, ecology, neurobiology, and 3-D reconstructions, have flourished, despite a rather meager environment for the funding of such work. In the past twenty years, the kind and scope of such interactions between mathematicians and biologists have changed dramatically, reaching out to encompass areas of both biology and mathematics that previously had not benefited. At the same time, with the closer integration of theory and experiment, and the increased reliance on high-speed computation,more » the costs of such research grew, though not the opportunities for funding. The perception became reinforced, both within the research community and at funding agencies, that although these interactions were expanding, they were not doing so at the rate necessary to meet the opportunities and needs. A workshop was held in Washington, DC, between April 28 and May 3, 1990 which drew together a broadly based group of researchers to synthesize conclusions from a group of working papers and extended discussions. The result is the report presented here, which we hope will provide a guide and stimulus to research in mathematical and computational biology for at least the next decade. The report identifies a number of grand challenges, representing a broad consensus among the participants.« less

  5. Cross-disciplinary research in cancer: an opportunity to narrow the knowledge–practice gap

    PubMed Central

    Urquhart, R.; Grunfeld, E.; Jackson, L.; Sargeant, J.; Porter, G.A.

    2013-01-01

    Health services researchers have consistently identified a gap between what is identified as “best practice” and what actually happens in clinical care. Despite nearly two decades of a growing evidence-based practice movement, narrowing the knowledge–practice gap continues to be a slow, complex, and poorly understood process. Here, we contend that cross-disciplinary research is increasingly relevant and important to reducing that gap, particularly research that encompasses the notion of transdisciplinarity, wherein multiple academic disciplines and non-academic individuals and groups are integrated into the research process. The assimilation of diverse perspectives, research approaches, and types of knowledge is potentially effective in helping research teams tackle real-world patient care issues, create more practice-based evidence, and translate the results to clinical and community care settings. The goals of this paper are to present and discuss cross-disciplinary approaches to health research and to provide two examples of how engaging in such research may optimize the use of research in cancer care. PMID:24311951

  6. Cross-disciplinary research in cancer: an opportunity to narrow the knowledge-practice gap.

    PubMed

    Urquhart, R; Grunfeld, E; Jackson, L; Sargeant, J; Porter, G A

    2013-12-01

    Health services researchers have consistently identified a gap between what is identified as "best practice" and what actually happens in clinical care. Despite nearly two decades of a growing evidence-based practice movement, narrowing the knowledge-practice gap continues to be a slow, complex, and poorly understood process. Here, we contend that cross-disciplinary research is increasingly relevant and important to reducing that gap, particularly research that encompasses the notion of transdisciplinarity, wherein multiple academic disciplines and non-academic individuals and groups are integrated into the research process. The assimilation of diverse perspectives, research approaches, and types of knowledge is potentially effective in helping research teams tackle real-world patient care issues, create more practice-based evidence, and translate the results to clinical and community care settings. The goals of this paper are to present and discuss cross-disciplinary approaches to health research and to provide two examples of how engaging in such research may optimize the use of research in cancer care.

  7. Creating collaboration opportunities for marine research across the Arctic: The SEARCH-ACCESS partnership and an emerging sea ice prediction research network

    NASA Astrophysics Data System (ADS)

    Eicken, H.; Bitz, C. M.; Gascard, J.; Kaminski, T.; Karcher, M. J.; Kauker, F.; Overland, J. E.; Stroeve, J. C.; Wiggins, H. V.

    2013-12-01

    Rapid Arctic environmental and socio-economic change presents major challenges and opportunities to Arctic residents, government agencies and the private sector. The Arctic Ocean and its ice cover, in particular, are in the midst of transformative change, ranging from declines in sea-ice thickness and summer ice extent to threats to coastal communities and increases in maritime traffic and offshore resource development. The US interagency Study of Environmental Arctic Change (SEARCH) and the European Arctic Climate Change, Economy and Society (ACCESS) project are addressing both scientific research needs and stakeholder information priorities to improve understanding and responses to Arctic change. Capacity building, coordination and integration of activities at the international level and across sectors and stakeholder groups are major challenges that have to be met. ACCESS and SEARCH build on long-standing collaborations with a focus on environmental change in the Arctic ocean-ice-atmosphere system and the most pressing research needs to inform marine policy, resource management and threats to Arctic coastal communities. To illustrate the approach, key results and major conclusions from this international coordination and collaboration effort, we focus on a nascent sea-ice prediction research network. This activity builds on the Arctic Sea Ice Outlook that was initiated by SEARCH and the European DAMOCLES project (a precursor to ACCESS) and has now grown into an international community of practice that synthesizes, evaluates and discusses sea-ice predictions on seasonal to interannual scales. Key goals of the effort which is now entering into a new phase include the comparative evaluation of different prediction approaches, including the combination of different techniques, the compilation of reference datasets and model output, guidance on the design and implementation of observing system efforts to improve predictions and information transfer into private

  8. EMPLOYMENT OPPORTUNITIES IN NCEA

    EPA Science Inventory

    Career Appointments:

  9. Creating Research/STEM Opportunities for Students - A Case for Collaboration

    NASA Astrophysics Data System (ADS)

    Baker, R. W.; Sprenger, A.

    2016-02-01

    A unique collaboration between a Regional Coastal Ocean Observing System, the Northwest Association of Networked Ocean Observing Systems, (NANOOS), a boat-based ocean science education non-profit organization, the Ocean Inquiry Project (OIP), an informal environmental education center, the Whidbey Watershed Stewards (WWS), and the South Whidbey School District, has resulted in an incredible STEM learning opportunity for middle school students. The year-long program challenges 200 6th and 7th graders at Langley Middle School on Whidbey Island WA, to investigate the fragile connection between the biotic and abiotic ocean, with a focus on ocean acidification, a growing environmental, economic concern in the school's local waters of Puget Sound. Students use a variety of field research techniques to collect original ocean data at a local marina, building an oceanographic time-series, over a 6 month time period (Nov - Apr) as the earth and ocean transition from winter into spring. Students have named their study "SWOOS" - the South Whidbey Ocean Observing Station. Every month, students measure parameters in seawater including temperature, salinity, pH, oxygen, and nitrates from their research site. Plankton samples are also collected and brought back to their science classroom to be analyzed. Students design and build their own "student buoys", which are deployed near the Langley Marina to collect temperature and light data throughout the 6-month research project. Students work with NANOOS staff to compare their data with data from other shore stations and buoys throughout Puget Sound and along the WA coast. The program culminates with a one-day oceanography cruise aboard a research vessel with state of the art equipment collecting data and working alongside University of Washington graduate students and scientists. Our program uses students' local environment, a variety of ocean research techniques and a compelling environmental issue to give students comprehensive

  10. Direct heat geothermal opportunities at Pahoa, Hawaii

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moreau, J.; Jones, W.L.

    1980-09-01

    A geothermal commercial park located near Pahoa, Hawaii, has been found to be technically feasible. However, community acceptance varies from optimistic support for the job opportunities to only lukewarm acceptance by most residents of the nearby planned residential community. Interviews, team evaluations, and calculations of energy and transportation savings were used to reduce a list of candidate processes to four. These four include an ethanol plant, a cattle feed mill, a protein recovery plant, and a papaya processing facility. In addition, a research laboratory is planned for the evaluation of other processes identified as very promising.

  11. Status and opportunities for genomics research with rainbow trout

    USGS Publications Warehouse

    Thorgaard, G.H.; Bailey, G.S.; Williams, D.; Buhler, D.R.; Kaattari, S.L.; Ristow, S.S.; Hansen, J.D.; Winton, J.R.; Bartholomew, J.L.; Nagler, J.J.; Walsh, P.J.; Vijayan, M.M.; Devlin, R.H.; Hardy, R.W.; Overturf, K.E.; Young, W.P.; Robison, B.D.; Rexroad, C.; Palti, Y.

    2002-01-01

    The rainbow trout (Oncorhynchus mykiss) is one of the most widely studied of model fish species. Extensive basic biological information has been collected for this species, which because of their large size relative to other model fish species are particularly suitable for studies requiring ample quantities of specific cells and tissue types. Rainbow trout have been widely utilized for research in carcinogenesis, toxicology, comparative immunology, disease ecology, physiology and nutrition. They are distinctive in having evolved from a relatively recent tetraploid event, resulting in a high incidence of duplicated genes. Natural populations are available and have been well characterized for chromosomal, protein, molecular and quantitative genetic variation. Their ease of culture, and experimental and aquacultural significance has led to the development of clonal lines and the widespread application of transgenic technology to this species. Numerous microsatellites have been isolated and two relatively detailed genetic maps have been developed. Extensive sequencing of expressed sequence tags has begun and four BAC libraries have been developed. The development and analysis of additional genomic sequence data will provide distinctive opportunities to address problems in areas such as evolution of the immune system and duplicate genes. ?? 2002 Elsevier Science Inc. All rights reserved.

  12. "Restricted Community Members": Research Protections and Opportunities for Individuals Committed to Assisted Outpatient Treatment.

    PubMed

    Segal, Andrea G; Sisti, Dominic A

    2017-02-01

    Several forms of mandated community treatment exist in the United States. One mechanism, assisted outpatient treatment (AOT), has become both more common and more controversial in recent years. The status of individuals committed to AOT remains unclear within regulatory guidelines aimed at protecting research participants. Should individuals on AOT be considered psychiatric inpatients, prisoners, community members, or something else? The authors argue that persons on AOT inhabit a gray area wherein they should be given some of the ethical protections afforded to involuntary inpatients and prisoners, but they should also enjoy freedoms as members of the community. The authors' term for this population is "restricted community members." The need to protect individuals in this population from potentially coercive forces of AOT while also offering them the opportunity to participate in research is especially acute in areas of research where the need is great: serious mental illness and substance use disorders.

  13. Cultural Differences in Opportunity Cost Consideration

    PubMed Central

    Zhang, Ning; Ji, Li-Jun; Li, Ye

    2017-01-01

    Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2). Across both indexes, we found that after controlling for individual difference variables and amount of pocket money, Chinese participants in China considered financial opportunity cost more than Euro-Canadians in Study 1. Similar results were observed in Study 2 when comparing Chinese in Canada with Euro-Canadians However, the cultural effect on opportunity cost consideration was confounded by family income in Study 2. Implications for resource management, limitations of the current research and directions for future research are discussed. PMID:28184202

  14. Cultural Differences in Opportunity Cost Consideration.

    PubMed

    Zhang, Ning; Ji, Li-Jun; Li, Ye

    2017-01-01

    Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2). Across both indexes, we found that after controlling for individual difference variables and amount of pocket money, Chinese participants in China considered financial opportunity cost more than Euro-Canadians in Study 1. Similar results were observed in Study 2 when comparing Chinese in Canada with Euro-Canadians However, the cultural effect on opportunity cost consideration was confounded by family income in Study 2. Implications for resource management, limitations of the current research and directions for future research are discussed.

  15. Facilitating mental health research for patients, clinicians and researchers: a mixed-method study

    PubMed Central

    Robotham, D; Waterman, S; Oduola, S; Papoulias, C; Craig, T; Wykes, T

    2016-01-01

    Objectives Research registers using Consent for Contact (C4C) can facilitate recruitment into mental health research studies, allowing investigators to contact patients based on clinical records information. We investigated whether such a register was useful for mental health research, seeking the perspectives of patients and research investigators. Setting and design In 2012, a C4C register was developed in a large secondary mental health provider within the UK; almost 9000 patients have joined. This mixed-method study audited the effectiveness of the register. Participants A ‘mystery shopper’ exercise was conducted, and patients (n=21) were recruited to ask clinicians about the availability of research opportunities. Structured interviews were conducted with patients (n=52) about their experiences of being on the register. Similar interviews were conducted with 18 investigators from 19 studies, who had attempted to use the register to recruit participants. Outcome measures The impact of C4C on study recruitment, and whether it helped patients learn about research. Results So far, the register has provided 928 individuals with 1085 research opportunities (in 60% of cases, the individual agreed to participate in the study). Clinicians were willing to link patients to research opportunities, but often lacked information about studies. For patients, the register provided opportunities which they may not otherwise have; 27 of 52 had participated in studies since joining the register (18 participating for the first time). Most investigators used the register to supplement recruitment to their studies, but described problems in prescreening potential participants from a clinical record for complex studies. Conclusions Although the register helped investigators recruit for studies, and provided patients with research opportunities, clinicians' input is still useful for identifying suitable participants. C4C registers should be adapted to provide clinicians with

  16. Postdoctoral Opportunities and Career Options

    NASA Astrophysics Data System (ADS)

    Manka, R. H.

    2001-05-01

    Following the completion of a Ph.D. degree, in the sciences a postdoctoral appointment has traditionally been a key step in career development to expand the student's background and broaden their perspective. The postdoctoral appointment often is almost a requirement to obtain some positions in academia and government laboratories. In addition, postdoctoral positions in industry are becoming more common and offer an opportunity to explore a field without making a long-term commitment. We describe the nature of a postdoctoral appointment and discuss the advantages and disadvantages of the recent Ph.D. taking a postdoctoral position. We comment on the role such positions play in university, government and the corporate research. Finally, we describe some of the national postdoctoral opportunities that exist including large programs offered by the National Research Council through Federal laboratories including those of NASA, NOAA, EPA, and the Department of Defense. Exciting new interdisciplinary opportunities such as fellowships at the NASA Astrobiology Institute are summarized, as are international opportunities such as the von Humboldt fellowships in Germany.

  17. Race, Socioeconomic Status and Health: Complexities, Ongoing Challenges and Research Opportunities

    PubMed Central

    Williams, David R.; Mohammed, Selina A.; Leavell, Jacinta; Collins, Chiquita

    2012-01-01

    This paper provides an overview of racial variations in health and shows that differences in socioeconomic status (SES) across racial groups are a major contributor to racial disparities in health. However, race reflects multiple dimensions of social inequality and individual and household indicators of SES capture relevant but limited aspects of this phenomenon. Research is needed that will comprehensively characterize the critical pathogenic features of social environments and identify how they combine with each other to affect health over the life course. Migration history and status are also important predictors of health and research is needed that will enhance understanding of the complex ways in which race, SES, and immigrant status combine to affect health. Fully capturing the role of race in health also requires rigorous examination of the conditions under which medical care and genetic factors can contribute to racial and SES differences in health. The paper identifies research priorities in all of these areas. PMID:20201869

  18. Race, socioeconomic status, and health: complexities, ongoing challenges, and research opportunities.

    PubMed

    Williams, David R; Mohammed, Selina A; Leavell, Jacinta; Collins, Chiquita

    2010-02-01

    This paper provides an overview of racial variations in health and shows that differences in socioeconomic status (SES) across racial groups are a major contributor to racial disparities in health. However, race reflects multiple dimensions of social inequality and individual and household indicators of SES capture relevant but limited aspects of this phenomenon. Research is needed that will comprehensively characterize the critical pathogenic features of social environments and identify how they combine with each other to affect health over the life course. Migration history and status are also important predictors of health and research is needed that will enhance understanding of the complex ways in which race, SES, and immigrant status combine to affect health. Fully capturing the role of race in health also requires rigorous examination of the conditions under which medical care and genetic factors can contribute to racial and SES differences in health. The paper identifies research priorities in all of these areas.

  19. Forensic Nursing State of the Science: Research and Practice Opportunities.

    PubMed

    Drake, Stacy A; Koetting, Cathy; Thimsen, Kathi; Downing, Nancy; Porta, Carolyn; Hardy, Peggy; Valentine, Julie L; Finn, Cris; Engebretson, Joan

    The International Association of Forensic Nurses (IAFN) is the only nursing organization advancing the forensic nursing specialty. The organization seeks to advance the profession, and one mechanism for doing so is development of a research agenda. The purpose of this action-based research study was to aid in the development of a forensic nursing research agenda. The study was carried out in two integral stages: (a) focus groups with IAFN members attending the annual conference and (b) reviewing posted IAFN member listserv material. The findings of this study identified similar gaps of other nursing specialties experiencing "growing pains," including role confusion and variation in educational preparation. Findings from this study will inform development of the IAFN 5-year research agenda to advance forensic nursing science and evidence-based practice.

  20. Metastable Eutectic Equilibrium in Natural Environments: Recent Development and Research Opportunities

    NASA Technical Reports Server (NTRS)

    Rietmeijer, Frans J. M.; Nuth, Joseph A., III; Jablonska, Mariola; Karner, James M.

    2000-01-01

    Chemical ordering at metastable eutectics was recognized in non-equilibrium gas-to- solid condensation experiments to constrain 'silicate' dust formation in O-rich circumstellar environments. The predictable metastable eutectic behavior successfully predicted the observed ferromagnesiosilica compositions of circumstellar dust presolar and solar nebula grains in the matrix of the collected aggregate IDPs (Interplanetary Dust Particles). Many of the experimentally determined metastable eutectic solids match the fundamental building blocks of common rock-forming layer silicates: this could have implications for the origin of Life. The physical conditions conducive to metastable eutectic behavior, i.e. high temperature and (ultra) fast quenching, lead to unique amorphous, typically nano- to micrometer-sized, materials. The new paradigm of metastable eutectic behavior opens the door to new and exciting research opportunities in uncovering the many implications of these unique amorphous, and typically nano-to micrometer-sized, metastable eutectic materials.

  1. Metastable Eutectic Equilibrium in Natural Environments: Recent Developments and Research Opportunities

    NASA Technical Reports Server (NTRS)

    Rietmeijer, Fans J. M.; Nuth, Joseph A., II; Jablonska, Mariola; Karner, James M.

    2000-01-01

    Chemical ordering at metastable eutectics was recognized in non-equilibrium gas-to- solid condensation experiments to constrain 'silicate' dust formation in O-rich circumstellar environments. The predictable metastable eutectic behavior successfully predicted the observed ferromagnesiosilica, compositions of circumstellar dust, presolar and solar nebula grains in the matrix of the collected aggregate IDPs. Many of the experimentally determined metastable eutectic solids match the fundamental building blocks of common rock-forming layer silicates: this could have implications for the origin of Life. The physical conditions conducive to metastable eutectic behavior, i.e. high temperature and (ultra)fast quenching, lead to unique amorphous, typically nano- to micrometer-sized, materials. The new paradigm of metastable eutectic behavior opens the door to new and exciting research opportunities in uncovering the many implications of these unique amorphous and typically nano- to micrometer-sized, metastable eutectic materials.

  2. Using a research framework to identify knowledge gaps in research on food marketing to children in Australia.

    PubMed

    Chapman, Kathy; Kelly, Bridget; King, Lesley

    2009-06-01

    Research in the field of food marketing to children requires a better understanding of the research gaps in order to inform policy development. The purpose of this paper was to propose a framework for classifying food marketing research, using Australian research on food marketing to children to demonstrate how this framework can be used to determine knowledge gaps. A literature review of research databases and 'grey' material was conducted to identify research from the previous 10 years. Studies were classified according to their research focus, and media type, as either: exposure, including content analyses; effects of exposure, including opinions, attitudes and actions resulting from food marketing exposure; regulations, including the type and level of regulation that applies to food marketing; or breaches of regulations, including instances where marketing regulations have been violated. The majority of Australian research on food marketing to children has focused on television advertising and exposure research. Research has consistently shown that the content of food marketing directed at children is predominately for unhealthy foods. There is a lack of research on the effects of food marketing, which would be valuable to inform policy. The development of a logical framework for food marketing research allows for the identification of research gaps and enables research priorities to be identified.

  3. 12 CFR 268.102 - Board program for equal employment opportunity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Opportunity § 268.102 Board program for equal employment opportunity. (a) The Board shall maintain a continuing affirmative program to promote equal opportunity and to identify and eliminate discriminatory... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Board program for equal employment opportunity...

  4. Federal Funding Opportunities - National Site for the Regional IPM Centers

    Science.gov Websites

    Pest Management (CPPM) Small Business Innovation Research (SBIR) Sustainable Agriculture (SARE ) Specialty Crop Research Initiative / Citrus Disease Research and Extension Organic Agriculture Research and Opportunities Funding Opportunities Database United States Department of Agriculture - National Institute of

  5. A Twenty-Two-Year-Old Community Advisory Board: Health Research as an Opportunity for Social Change.

    PubMed

    Silvestre, Anthony J; Quinn, Sandra J; Rinaldo, Charles R

    2010-01-01

    Conducting health research often requires a partnership between marginalized communities and researchers. Community organizers can broker this partnership in a way that not only produces important scientific discoveries but also brings needed resources to the communities. This article is a description of a community advisory board established in 1984 to advise researchers on a longitudinal study of the natural history of AIDS among gay men. The Board successfully guided the recruitment of more than 3,000 gay and bisexual male volunteers and, at the same time worked as a powerful change agent. An analysis of minutes from all Board meetings between 1984-2006 indicates that significant social change as well as important research findings resulted from Board actions. Community organizers who work to create a mutually beneficial partnership between communities and researchers may find new opportunities to support community growth and social justice.

  6. Ethical challenges and opportunities for nurses in HIV and AIDS community-based participatory research in Jamaica.

    PubMed

    Davison, Colleen M; Kahwa, Eulalia; Atkinson, Uki; Hepburn-Brown, Cerese; Aiken, Joyette; Dawkins, Pauline; Rae, Tania; Edwards, Nancy; Roelofs, Susan; MacFarlane, Denise

    2013-02-01

    As part of a multinational program of research, we undertook a community-based participatory research project in Jamaica to strengthen nurses' engagement in HIV and AIDS policy. Three leadership hubs were purposefully convened and included small groups of people (6-10) from diverse HIV and AIDS stakeholder groups in Jamaica: frontline nurses and nurse managers in primary and secondary care settings; researchers; health care decision makers; and other community members. People living with HIV or AIDS were among the hub members. Using a relational public health ethics framework, we outline some of the ethical challenges and opportunities experienced by the research team and the leadership hubs. Data included research assistant field notes and hub progress reports. Emerging ethical concerns were associated with relational personhood, social justice, relational autonomy, relational solidarity, and sustainability of the hub activities.

  7. Unintended pregnancy amongst an early pregnancy clinic cohort: Identifying opportunities for preventative health interventions.

    PubMed

    Cheney, Kate; Sim, Kyra A; D'souza, Mario; Pelosi, Marilena; Black, Kirsten I

    2016-08-01

    A relationship between maternal weight and unintended pregnancy has previously been reported. Researchers have found women who are overweight and obese women are less likely to use contraception, and more likely to have unplanned pregnancies, thus limiting their ability to optimise their health before conception. This study sought to examine the relationship between pregnancy intention and body mass index (BMI) amongst women attending a service managing early pregnancy complications. The cross-sectional descriptive study (n = 550) was conducted from November 2013 to February 2015 in Sydney, Australia. It documented women's pregnancy intention using a self-completed questionnaire incorporating a validated pregnancy intention scale and measuring women's height and weight to calculate their BMI using the WHO classification of anthropometry and adjusting for cut-offs in Asian populations. Socio-demographic characteristics were also documented. The respondents were ethnically diverse with over a third defining themselves as Asian (36%; 196). Forty-four per cent of women (239) had clearly intended their pregnancy, 39% (212) were ambivalent and 18% (99) had not intended to conceive. Forty-nine per cent (263) of women were overweight or obese. No relationship was found between pregnancy intention and BMI. Fewer than half the women with early pregnancy complications clearly intended to be pregnant. Contrary to previous research, pregnancy intention was not associated with maternal weight. Underutilised opportunities for lifestyle and preconception education exist to address the impact of modifiable maternal behaviours on future pregnancies and to provide contraception counselling to those not wishing to conceive. © 2016 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  8. Energy-Water Microgrid Opportunity Analysis at the University of Arizona's Biosphere 2 Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daw, Jennifer A; Kandt, Alicen J; Macknick, Jordan E

    Microgrids provide reliable and cost-effective energy services in a variety of conditions and locations. There has been minimal effort invested in developing energy-water microgrids that demonstrate the feasibility and leverage synergies of operating renewable energy and water systems in a coordinated framework. Water systems can be operated in ways to provide ancillary services to the electrical grid and renewable energy can be utilized to power water-related infrastructure, but the potential for co-managed systems has not yet been quantified or fully characterized. Energy-water microgrids could be a promising solution to improve energy and water resource management for islands, rural communities, distributedmore » generation, Defense operations, and many parts of the world lacking critical infrastructure. NREL and the University of Arizona have been jointly researching energy-water microgrid opportunities at the University's Biosphere 2 (B2) research facility. B2 is an ideal case study for an energy-water microgrid test site, given its size, its unique mission and operations, the criticality of water and energy infrastructure, and its ability to operate connected to or disconnected from the local electrical grid. Moreover, the B2 is a premier facility for undertaking agricultural research, providing an excellent opportunity to evaluate connections and tradeoffs at the food-energy-water nexus. In this study, NREL used the B2 facility as a case study for an energy-water microgrid test site, with the potential to catalyze future energy-water system integration research. The study identified opportunities for energy and water efficiency and estimated the sizes of renewable energy and storage systems required to meet remaining loads in a microgrid, identified dispatchable loads in the water system, and laid the foundation for an in-depth energy-water microgrid analysis. The foundational work performed at B2 serves a model that can be built upon for identifying

  9. Global opportunities for mariculture development to promote human nutrition

    PubMed Central

    Molina, Renato; Wilson, Margaret; Halpern, Benjamin S.

    2018-01-01

    An estimated two billion people worldwide currently suffer from micronutrient malnutrition, and almost one billion are calorie deficient. Providing adequate nutrition is a growing global challenge. Seafood is one of the most important sources of both protein and micronutrients for many, yet production from wild capture fisheries has stagnated. In contrast, aquaculture is the world’s fastest-growing food production sector and now supplies over half of all seafood consumed globally. Mariculture, or the farming of brackish and marine species, accounts for roughly one-third of all aquaculture production and has received increasing attention as a potential supplement for wild-caught marine fisheries. By analyzing global patterns in seafood reliance, malnutrition levels, and economic opportunity, this study identifies where mariculture has the greatest potential to improve human nutrition. We calculate a mariculture opportunity index for 117 coastal nations by drawing on a diverse set of seafood production, trade, consumption, and nutrition data. Seventeen primary variables are combined into country-level scores for reliance on seafood, opportunity for nutritional improvement, and opportunity for economic development of mariculture. The final mariculture opportunity score identifies countries with high seafood reliance combined with high nutritional and economic opportunity scores. We find that island nations in Southeast Asia and the Caribbean are consistently identified as countries with high mariculture opportunity. In other regions, nutritional and economic opportunity scores are not significantly correlated, and we discuss the implications of this finding for crafting appropriate development policy. Finally, we identify key challenges to ameliorating malnutrition through mariculture development, including insufficient policy infrastructure, government instability, and ensuring local consumption of farmed fish. Our analysis is an important step towards prioritizing

  10. Government Cloud Computing Policies: Potential Opportunities for Advancing Military Biomedical Research.

    PubMed

    Lebeda, Frank J; Zalatoris, Jeffrey J; Scheerer, Julia B

    2018-02-07

    This position paper summarizes the development and the present status of Department of Defense (DoD) and other government policies and guidances regarding cloud computing services. Due to the heterogeneous and growing biomedical big datasets, cloud computing services offer an opportunity to mitigate the associated storage and analysis requirements. Having on-demand network access to a shared pool of flexible computing resources creates a consolidated system that should reduce potential duplications of effort in military biomedical research. Interactive, online literature searches were performed with Google, at the Defense Technical Information Center, and at two National Institutes of Health research portfolio information sites. References cited within some of the collected documents also served as literature resources. We gathered, selected, and reviewed DoD and other government cloud computing policies and guidances published from 2009 to 2017. These policies were intended to consolidate computer resources within the government and reduce costs by decreasing the number of federal data centers and by migrating electronic data to cloud systems. Initial White House Office of Management and Budget information technology guidelines were developed for cloud usage, followed by policies and other documents from the DoD, the Defense Health Agency, and the Armed Services. Security standards from the National Institute of Standards and Technology, the Government Services Administration, the DoD, and the Army were also developed. Government Services Administration and DoD Inspectors General monitored cloud usage by the DoD. A 2016 Government Accountability Office report characterized cloud computing as being economical, flexible and fast. A congressionally mandated independent study reported that the DoD was active in offering a wide selection of commercial cloud services in addition to its milCloud system. Our findings from the Department of Health and Human Services

  11. NASA GSFC Opportunities for STEM Professionals Using the Vantage Point of Space

    NASA Technical Reports Server (NTRS)

    Meeson, Blanche W.; Robbins, Geraldine B.

    2012-01-01

    NASA has a variety of learning opportunities for STEM professionals. Three opportunities at GSFC are examined in this chapter: 1) standard summer research and development internship for undergraduates, 2) senior internship for undergraduate and graduate students and 3) a workshop series for informal learning center professionals. We describe these programs, examine their evolution with respect to most effective education practices and their assessment and evaluation, and identify the similarities and differences between them. The internship programs highlight authentic project-based research and development experiences with the senior internship providing a richer, deeper, and more demanding experience that has greater professional value. The workshops for informal learning center professionals on-the-other hand, focus on building knowledge of GSFC s science and engineering strengths among these professionals, and on building enduring partnerships between individuals (participants and GSFC scientist, engineers and educators) and between organizations (GSFC and the informal learning center). Finally, we examine the characteristics of these programs from a design and management perspective. Through this examination we identify a general structure that provides insight into more effective design and management of similar education programs.

  12. Genomics pipelines and data integration: challenges and opportunities in the research setting

    PubMed Central

    Davis-Turak, Jeremy; Courtney, Sean M.; Hazard, E. Starr; Glen, W. Bailey; da Silveira, Willian; Wesselman, Timothy; Harbin, Larry P.; Wolf, Bethany J.; Chung, Dongjun; Hardiman, Gary

    2017-01-01

    Introduction The emergence and mass utilization of high-throughput (HT) technologies, including sequencing technologies (genomics) and mass spectrometry (proteomics, metabolomics, lipids), has allowed geneticists, biologists, and biostatisticians to bridge the gap between genotype and phenotype on a massive scale. These new technologies have brought rapid advances in our understanding of cell biology, evolutionary history, microbial environments, and are increasingly providing new insights and applications towards clinical care and personalized medicine. Areas covered The very success of this industry also translates into daunting big data challenges for researchers and institutions that extend beyond the traditional academic focus of algorithms and tools. The main obstacles revolve around analysis provenance, data management of massive datasets, ease of use of software, interpretability and reproducibility of results. Expert Commentary The authors review the challenges associated with implementing bioinformatics best practices in a large-scale setting, and highlight the opportunity for establishing bioinformatics pipelines that incorporate data tracking and auditing, enabling greater consistency and reproducibility for basic research, translational or clinical settings. PMID:28092471

  13. Sociotechnical approaches to workplace safety: Research needs and opportunities.

    PubMed

    Robertson, Michelle M; Hettinger, Lawrence J; Waterson, Patrick E; Noy, Y Ian; Dainoff, Marvin J; Leveson, Nancy G; Carayon, Pascale; Courtney, Theodore K

    2015-01-01

    The sociotechnical systems perspective offers intriguing and potentially valuable insights into problems associated with workplace safety. While formal sociotechnical systems thinking originated in the 1950s, its application to the analysis and design of sustainable, safe working environments has not been fully developed. To that end, a Hopkinton Conference was organised to review and summarise the state of knowledge in the area and to identify research priorities. A group of 26 international experts produced collaborative articles for this special issue of Ergonomics, and each focused on examining a key conceptual, methodological and/or theoretical issue associated with sociotechnical systems and safety. In this concluding paper, we describe the major conference themes and recommendations. These are organised into six topic areas: (1) Concepts, definitions and frameworks, (2) defining research methodologies, (3) modelling and simulation, (4) communications and decision-making, (5) sociotechnical attributes of safe and unsafe systems and (6) potential future research directions for sociotechnical systems research. Sociotechnical complexity, a characteristic of many contemporary work environments, presents potential safety risks that traditional approaches to workplace safety may not adequately address. In this paper, we summarise the investigations of a group of international researchers into questions associated with the application of sociotechnical systems thinking to improve worker safety.

  14. Sociotechnical approaches to workplace safety: Research needs and opportunities

    PubMed Central

    Robertson, Michelle M.; Hettinger, Lawrence J.; Waterson, Patrick E.; Ian Noy, Y.; Dainoff, Marvin J.; Leveson, Nancy G.; Carayon, Pascale; Courtney, Theodore K.

    2015-01-01

    The sociotechnical systems perspective offers intriguing and potentially valuable insights into problems associated with workplace safety. While formal sociotechnical systems thinking originated in the 1950s, its application to the analysis and design of sustainable, safe working environments has not been fully developed. To that end, a Hopkinton Conference was organised to review and summarise the state of knowledge in the area and to identify research priorities. A group of 26 international experts produced collaborative articles for this special issue of Ergonomics, and each focused on examining a key conceptual, methodological and/or theoretical issue associated with sociotechnical systems and safety. In this concluding paper, we describe the major conference themes and recommendations. These are organised into six topic areas: (1) Concepts, definitions and frameworks, (2) defining research methodologies, (3) modelling and simulation, (4) communications and decision-making, (5) sociotechnical attributes of safe and unsafe systems and (6) potential future research directions for sociotechnical systems research. Practitioner Summary: Sociotechnical complexity, a characteristic of many contemporary work environments, presents potential safety risks that traditional approaches to workplace safety may not adequately address. In this paper, we summarise the investigations of a group of international researchers into questions associated with the application of sociotechnical systems thinking to improve worker safety. PMID:25728246

  15. Attention-Deficit/Hyperactivity Disorder and Risk of Substance Use Disorder: Developmental Considerations, Potential Pathways, and Opportunities for Research

    PubMed Central

    Molina, Brooke S.G.; Pelham, William E.

    2014-01-01

    Many opportunities to explain ADHD-related risk of substance use/disorder (SUD) remain available for study. We detail these opportunities by considering characteristics of children with ADHD and factors affecting their outcomes side-by-side with overlapping variables in the developmental literature on SUD etiology. Although serious conduct problems are a known contributor to ADHD-related risk of SUD, few studies have considered their emergence developmentally and in relation to other candidate mediators and moderators that could also explain risk and be intervention targets. Common ADHD-related impairments, such as school difficulties, are in need of research. Heterogeneous social impairments have the potential for predisposing, and buffering, influences. Research on neurocognitive domains should move beyond standard executive function batteries to measure deficits in the interface between cognitive control, reward, and motivation. Ultimately, maximizing prediction will depend, as it has in the SUD literature, on simultaneous consideration of multiple risk factors. PMID:24437435

  16. CCR researchers identify pathway critical for preventing premature aging | Center for Cancer Research

    Cancer.gov

    Hutchinson-Gilford progeria syndrome (HGPS) is a rare, fatal disease in which patients age prematurely. To identify primary HGPS driver mechanisms, Nard Kubben, Ph.D., a Research Fellow in the laboratory of Tom Misteli, Ph.D., in CCR’s Laboratory of Receptor Biology and Gene Expression, and colleagues in the NCI High-throughput Imaging Facility developed an imaging-based

  17. Provider competition and health care quality: challenges and opportunities for research.

    PubMed

    Wong, Herbert S; McNamara, Peggy; Greenberg, Warren

    2004-06-01

    On May 28, 2003, the Agency for Healthcare Research and Quality and the Federal Trade Commission co-sponsored an invitational conference entitled, "Provider Competition and Quality: Latest Findings and Implications for the Next Generation of Research." The main objectives of this conference were to share and discuss the latest findings on provider competition and quality, to identify implications for antitrust policy, and to develop an agenda for further research in this area. While it is impossible to completely capture the rich exchange of ideas and perspectives that transpired at the conference, we highlight several key themes that emerged and present a research agenda to guide future investigations.

  18. Impact of tobacco regulation on animal research: new perspectives and opportunities.

    PubMed

    Donny, Eric C; Taylor, Tracy G; LeSage, Mark G; Levin, Melissa; Buffalari, Deanne M; Joel, Danielle; Sved, Alan F

    2012-11-01

    The Family Smoking Prevention and Tobacco Control Act in the United States and the World Health Organization Framework Convention on Tobacco or Health ratified by over 170 countries render scientific investigations into the abuse liability, harm, and effects of tobacco more critical than ever. A key area to explore relates to the potential regulation of nicotine content in cigarettes. Determining the nicotine content per cigarette below which smokers reliably reduce their consumption of and dependence on cigarettes, an idea proposed almost 20 years ago (Benowitz & Henningfield, 1994), could be a powerful approach to reduce the abuse liability and consequent harm from cigarettes. However, this approach is laden with potentially complex issues. Many of these complications can be studied using animal models, but they require a particular perspective. Herein, we review several challenges for animal researchers interested in nicotine reduction as examples of how this perspective dictates new approaches to animal research. These include defining the threshold nicotine dose for maintaining self-administration, evaluating the differential impact of various implementation strategies, assessing the factors that could interact with nicotine to alter the reinforcement threshold, describing the role of cues in maintaining low dose nicotine self-administration, and examining individual differences in response to nicotine reduction. Researchers who study tobacco using animal models have the opportunity to play a central role in the regulatory science of tobacco and conduct studies that directly inform policy decisions that could impact the lives of millions.

  19. Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

    PubMed

    Uc, Aliye; Andersen, Dana K; Bellin, Melena D; Bruce, Jason I; Drewes, Asbjørn M; Engelhardt, John F; Forsmark, Christopher E; Lerch, Markus M; Lowe, Mark E; Neuschwander-Tetri, Brent A; OʼKeefe, Stephen J; Palermo, Tonya M; Pasricha, Pankaj; Saluja, Ashok K; Singh, Vikesh K; Szigethy, Eva M; Whitcomb, David C; Yadav, Dhiraj; Conwell, Darwin L

    2016-11-01

    A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities in chronic pancreatitis (CP) and its sequelae. This conference marked the 20th year anniversary of the discovery of the cationic trypsinogen (PRSS1) gene mutation for hereditary pancreatitis. The event was held on July 27, 2016, and structured into 4 sessions: (1) pathophysiology, (2) exocrine complications, (3) endocrine complications, and (4) pain. The current state of knowledge was reviewed; many knowledge gaps and research needs were identified that require further investigation. Common themes included the need to design better tools to diagnose CP and its sequelae early and reliably, identify predisposing risk factors for disease progression, develop standardized protocols to distinguish type 3c diabetes mellitus from other types of diabetes, and design effective therapeutic strategies through novel cell culture technologies, animal models mimicking human disease, and pain management tools. Gene therapy and cystic fibrosis conductance regulator potentiators as possible treatments of CP were discussed. Importantly, the need for CP end points and intermediate targets for future drug trials was emphasized.

  20. Research Opportunities in Solid Earth Science (RESESS): Broadening Participation in Geology and Geophysics (Invited)

    NASA Astrophysics Data System (ADS)

    Eriksson, S. C.; Hubenthal, M.

    2009-12-01

    RESESS is a multi-year, paid, summer research internship program designed for students from underrepresented groups. The students receive extensive mentoring in science research and communication and become part of a community that provides ongoing support. This has been possible in the initial 5 years of the program through collaboration with Significant Opportunities in Atmospheric Research and Science (SOARS), where solid earth students have been an integral part of the SOARS cohort, benefiting from social as well as educational interactions. 11 students have taken part in RESESS for at least one year and of these, four students have graduated in geoscience and entered graduate programs in geophysics and one was recently awarded an NSF graduate fellowship. Students have presented over 20 posters at national science meetings, and one has co-authored a peer-reviewed article. 23 scientists have mentored students over the past 5 years and 17 percent of these mentors are from underrepresented groups in science; 19 other scientists and university/science consortia staff have mentored students in written and verbal presentations and supported their integration into the local communities. Mentorship over a period of years is one important hallmark of this program as students have benefited from the support of UNAVCO, IRIS, USGS, and university scientists and staff during the summer, academic year, and at professional meetings such as AGU, GSA, NABGG, and SACNAS as well as consortia and project science workshops (UNAVCO, IRIS, and EarthScope). One goal of the project has been to educate the scientific community on the benefits of mentoring undergraduate students from underrepresented groups in STEM fields. Increasingly, scientists are approaching RESESS to include this program in their implementation of broader impacts. RESESS has been funded by NSF for the next five years with plans to expand the number of students, geographic and scientific diversity, and sources of

  1. Significant Opportunities in Atmospheric Research and Science (SOARS)

    NASA Astrophysics Data System (ADS)

    Wyndam, T.

    2002-12-01

    Science education is rapidly changing. It is becoming more exciting and challenging, and also more accessible. Little more than a decade ago, the dreams of students from historically underrepresented groups to successfully pursue careers in science were admirable, but mostly elusive. Today, while African Americans, Chicano/Hispanic/LatinoAmericans, and Native Americans make up 25% of the U.S.A. population, these groups combined constitute fewer than 7% of scientists and engineers in the labor force and approximately 3% of the current AMS membership. Achieving the goal of a diverse, internationally competitive, and globally engaged workforce of scientists, engineers, and well prepared citizens calls for different educational goals and strategies. In 1995 UCAR teamed up with NSF and established a program, SOARS, that extends science education and encourages university students from diverse backgrounds to sustain interests, develop skills, and create paths that lead them to careers in the atmospheric and related sciences. SOARS combines research opportunities with a comprehensive mentoring component and a number of other proven learning strategies to create a student (protégé) centered learning community. To date, seventy-two protégés have traveled this pathway. Thirteen protégés have completed their master's degrees and are SOARS alumni: Ten have entered the professional scientific workforce; four are enrolled in Ph.D. programs; and two are Ph.D. candidates. Twenty-four protégés are enrolled in graduate programs: Three are AMS graduate fellows; one an NSF graduate fellow. Forty-two protégés have completed bachelor's degrees; three have completed associate's degrees and are now enrolled in a four-year research university. SOARS sponsorship has expanded to include DOE, NASA, and NOAA. Though SOARS continues to learn from the experiences of its community of protégés and mentors, results to date suggest that it is a successful model.

  2. Identifying opportunities for nature engagement in cancer care practice and design: protocol for four-round modified electronic Delphi.

    PubMed

    Blaschke, Sarah; O'Callaghan, Clare C; Schofield, Penelope

    2017-03-08

    Opportunities to engage with nature have shown relevance in experiences of health and recovery of patients with cancer and are attracting interest in cancer care practice and design. Such healthcare innovations can widen the horizon of possible supportive care solutions but require deliberate and rigorous investigation to ensure responsible action is taken and wastage avoided. This protocol outlines a study designed to solicit knowledge from relevant experts drawn from a range of healthcare practitioners, management representatives, designers and researchers to explore levels of opinion consensus for determining opportunities for, and barriers to, providing helpful nature engagement in cancer care settings. A 4-round modified electronic Delphi methodology will be used to conduct a structured, iterative feedback process for querying and synthesising expert opinion. Round 1 administers an open-ended questionnaire to a panel of selected, relevant experts who will consider the own recommendations of patients with cancer for nature engagement (drawn from a preceding investigation) before contributing salient issues (items) with relevance to the topic. Round 2 circulates anonymised summaries of responses back to the experts who verify and, if they wish, reconsider their own responses. Rounds 3 and 4 determine and rank experts' top 10 items using a 10-point Likert-type scale. Descriptive statistics (median and mean scores) will be calculated to indicate the items' relative importance. Levels of consensus will be explored with consensus defined as 75% agreement. Ethics approval for this study was obtained from the Institution's Human Research Ethics Committee (blinded for review). It is anticipated that the results will be published in peer-reviewed journals and presented in a variety of forums. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  3. Faculty Use of Author Identifiers and Researcher Networking Tools

    ERIC Educational Resources Information Center

    Tran, Clara Y.; Lyon, Jennifer A.

    2017-01-01

    This cross-sectional survey focused on faculty use and knowledge of author identifiers and researcher networking systems, and professional use of social media, at a large state university. Results from 296 completed faculty surveys representing all disciplines (9.3% response rate) show low levels of awareness and variable resource preferences. The…

  4. Postsecondary Education Opportunity. The Mortenson Report on Public Policy Analysis of Opportunity for Postsecondary Education, 1995.

    ERIC Educational Resources Information Center

    Mortenson, Thomas G., Ed.

    1995-01-01

    This document is a collection of 12 issues of a monthly publication on public policy and postsecondary education opportunity. Each issue contains one or two main articles providing an analysis of research on trends in postsecondary education. The major articles in these issues are: (1) "The Challenge of Educational Opportunity in Public…

  5. A Twenty-Two-Year-Old Community Advisory Board: Health Research as an Opportunity for Social Change

    PubMed Central

    Silvestre, Anthony J.; Quinn, Sandra J.; Rinaldo, Charles R.

    2010-01-01

    Conducting health research often requires a partnership between marginalized communities and researchers. Community organizers can broker this partnership in a way that not only produces important scientific discoveries but also brings needed resources to the communities. This article is a description of a community advisory board established in 1984 to advise researchers on a longitudinal study of the natural history of AIDS among gay men. The Board successfully guided the recruitment of more than 3,000 gay and bisexual male volunteers and, at the same time worked as a powerful change agent. An analysis of minutes from all Board meetings between 1984-2006 indicates that significant social change as well as important research findings resulted from Board actions. Community organizers who work to create a mutually beneficial partnership between communities and researchers may find new opportunities to support community growth and social justice. PMID:20523763

  6. Technology in Parkinson's disease: Challenges and opportunities.

    PubMed

    Espay, Alberto J; Bonato, Paolo; Nahab, Fatta B; Maetzler, Walter; Dean, John M; Klucken, Jochen; Eskofier, Bjoern M; Merola, Aristide; Horak, Fay; Lang, Anthony E; Reilmann, Ralf; Giuffrida, Joe; Nieuwboer, Alice; Horne, Malcolm; Little, Max A; Litvan, Irene; Simuni, Tanya; Dorsey, E Ray; Burack, Michelle A; Kubota, Ken; Kamondi, Anita; Godinho, Catarina; Daneault, Jean-Francois; Mitsi, Georgia; Krinke, Lothar; Hausdorff, Jeffery M; Bloem, Bastiaan R; Papapetropoulos, Spyros

    2016-09-01

    The miniaturization, sophistication, proliferation, and accessibility of technologies are enabling the capture of more and previously inaccessible phenomena in Parkinson's disease (PD). However, more information has not translated into a greater understanding of disease complexity to satisfy diagnostic and therapeutic needs. Challenges include noncompatible technology platforms, the need for wide-scale and long-term deployment of sensor technology (among vulnerable elderly patients in particular), and the gap between the "big data" acquired with sensitive measurement technologies and their limited clinical application. Major opportunities could be realized if new technologies are developed as part of open-source and/or open-hardware platforms that enable multichannel data capture sensitive to the broad range of motor and nonmotor problems that characterize PD and are adaptable into self-adjusting, individualized treatment delivery systems. The International Parkinson and Movement Disorders Society Task Force on Technology is entrusted to convene engineers, clinicians, researchers, and patients to promote the development of integrated measurement and closed-loop therapeutic systems with high patient adherence that also serve to (1) encourage the adoption of clinico-pathophysiologic phenotyping and early detection of critical disease milestones, (2) enhance the tailoring of symptomatic therapy, (3) improve subgroup targeting of patients for future testing of disease-modifying treatments, and (4) identify objective biomarkers to improve the longitudinal tracking of impairments in clinical care and research. This article summarizes the work carried out by the task force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and the quality of life of individuals with PD. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder

  7. Online citizen science games: Opportunities for the biological sciences.

    PubMed

    Curtis, Vickie

    2014-12-01

    Recent developments in digital technologies and the rise of the Internet have created new opportunities for citizen science. One of these has been the development of online citizen science games where complex research problems have been re-imagined as online multiplayer computer games. Some of the most successful examples of these can be found within the biological sciences, for example, Foldit, Phylo and EteRNA. These games offer scientists the opportunity to crowdsource research problems, and to engage with those outside the research community. Games also enable those without a background in science to make a valid contribution to research, and may also offer opportunities for informal science learning.

  8. The Right Jobs: Identifying Career Advancement Opportunities for Low-Skilled Workers. A Guide for Public and Private Sector Workforce Development Practitioners. Advancement for Low-Wage Workers

    ERIC Educational Resources Information Center

    Goldberger, Susan; Lessell, Newell; Biswas, Radha Roy

    2005-01-01

    The Right Jobs provides workforce policymakers and directors of workforce development programs with a structured approach to: (1) Identifying the most promising employment opportunities within reach of low-skill workers; (2) Determining the postsecondary training and career preparation routes that will yield results for their clients; and (3)…

  9. Symbiotic New Program Development through Marketing Research.

    ERIC Educational Resources Information Center

    Urban, David J.; And Others

    1993-01-01

    The applicability of marketing research to development of college programs in collaboration with other institutions or individuals is discussed. It is recommended that college administrators conduct ongoing environmental scanning to identify major opportunities for joint programs, forming research groups to screen basic ideas and explore program…

  10. Opportunities for Geoscience Research Onboard Virgin Galactic's SpaceShipTwo

    NASA Astrophysics Data System (ADS)

    Pomerantz, W.; Beerer, I.; Stephens, K.; Griffith, J.; Persall, W.; Tizard, J.

    2012-12-01

    Virgin Galactic has developed a reusable spaceplane, called SpaceShipTwo (SS2), designed to make routine voyages into suborbital space. SS2 is air-launched from a jet aircraft at an altitude of 50,000 ft. before igniting its rocket motor engine. The vehicle reaches a maximum apogee as high as 110 km before gliding to a conventional runway landing. With the ability to fly multiple times per week, SS2 will be capable of providing routine access to a rarely sampled and poorly understood region of the atmosphere and ionosphere, making it a valuable platform for geoscience research. With a payload capacity up to 1300 lbs., SS2 provides access to space and the upper atmosphere for substantially larger payloads than sounding rockets and at a dramatically lower cost than orbital satellites. The main cabin provides as much as 500 cubic ft. of useable volume in a shirt-sleeve environment and payload mounting interfaces that are compatible with standard architectures, such as Middeck Lockers, Cargo Transfer Bags, and server racks. A flight test engineer will be available on board to operate payloads during flight. In the future, SS2 will also offer a variety of external payload mounting locations, enabling researchers to make frequent in situ measurements in the mesosphere (50-90 km), lower thermosphere (above 80 km), and lower ionosphere (above 60 km). SS2 may also offer optical quality windows, allowing optical investigations from main cabin payloads. Researchers will have access to their payloads until just hours before flight and within three hours post-flight. While commercial operations will begin out of Spaceport America in New Mexico, SS2 may eventually be able to launch from a variety of geographic locations. Funding to develop and fly payloads for SS2 is currently available through many NASA programs including the Flight Opportunities Program and the Game Changing Development Program. Virgin Galactic expects the SS2 research platform to enable significant progress

  11. Proceedings of Workshop on Priority Great Lakes Environmental Research Initiatives (Great Lakes Environmental Research Laboratory, Ann Arbor, Michigan, October 10-11, 1974).

    ERIC Educational Resources Information Center

    Pinsak, Arthur P., Ed.

    This publication contains the proceedings of a workshop held in Ann Arbor, Michigan to identify the priority Great Lakes environmental research initiatives. The five major objectives of the workshop include the determination of research initiatives, opportunities for university research communities to discuss and recommend future research…

  12. An Opportunity for Social Work Researchers: Climbing out of Educational Loan Debt

    ERIC Educational Resources Information Center

    Burnette, Catherine E.; McCleary, Jennifer S.

    2014-01-01

    Objectives: Recruitment of the needed doctoral level social workers is impeded upon when doctoral graduates experience greater educational debt burden, modest salaries, and limited opportunities for student loan debt repayment. The purpose of this article is to describe a promising opportunity to reduce doctoral level social workers'…

  13. Good and Bad Research Collaborations: Researchers’ Views on Science and Ethics in Global Health Research

    PubMed Central

    Parker, Michael; Kingori, Patricia

    2016-01-01

    There has been a dramatic rise in the scale and scope of collaborative global health research. A number of structural and scientific factors explain this growth and there has been much discussion of these in the literature. Little, if any, attention has been paid, however, to the factors identified by scientists and other research actors as important to successful research collaboration. This is surprising given that their decisions are likely to play a key role in the sustainability and effectiveness of global health research initiatives. In this paper, we report on qualitative research with leading scientists involved in major international research collaborations about their views on good and bad collaborations and the factors that inform their decision-making about joining and participating actively in research networks. We identify and discuss eight factors that researchers see as essential in judging the merits of active participation in global health research collaborations: opportunities for active involvement in cutting-edge, interesting science; effective leadership; competence of potential partners in and commitment to good scientific practice; capacity building; respect for the needs, interests and agendas of partners; opportunities for discussion and disagreement; trust and confidence; and, justice and fairness in collaboration. Our findings suggest that the sustainability and effectiveness of global health research collaborations has an important ethical or moral dimension for the research actors involved. PMID:27737006

  14. NASA's commercial research plans and opportunities

    NASA Technical Reports Server (NTRS)

    Arnold, Ray J.

    1992-01-01

    One of the primary goals of the National Aeronautics and Space Administration's (NASA) commercial space development plan is to encourage the development of space-based products and markets, along with the infrastructure and transportation that will support those products and markets. A three phased program has been instituted to carry out this program. The first phase utilizes government grants through the Centers for the Commercial Development of Space (CCDS) for space-related, industry driven research; the development of a technology data base; and the development of commercial space transportation and infrastructure. The second phase includes the development of these technologies by industry for new commercial markets, and features unique industry/government collaborations such as Joint Endeavor Agreements. The final phase will feature technical applications actually brought to the marketplace. The government's role will be to support industry required infrastructure to encourage start-up markets and industries through follow-on development agreements such as the Space Systems Development Agreement. The Office of Commercial Programs has an aggressive flight program underway on the Space Shuttle, suborbital rockets, orbital expendable launch vehicles, and the Commercial Middeck Accommodation Module with SPACEHAB Inc. The Office of Commercial Program's has been allocated 35 percent of the U.S. share of the Space Station Freedom resources for 1997 utilization. A utilization plan has been developed with the Centers for the Commercial Development of Space and has identified eleven materials processing and biotechnology payloads occupying 5 double racks in the pressurized module as well as two payloads external to the module in materials exposure and environment monitoring. The Office of Commercial Programs will rely on the Space Station Freedom to provide the long duration laboratory component for space-based commercial research.

  15. NASA's commercial research plans and opportunities

    NASA Astrophysics Data System (ADS)

    Arnold, Ray J.

    One of the primary goals of the National Aeronautics and Space Administration's (NASA) commercial space development plan is to encourage the development of space-based products and markets, along with the infrastructure and transportation that will support those products and markets. A three phased program has been instituted to carry out this program. The first phase utilizes government grants through the Centers for the Commercial Development of Space (CCDS) for space-related, industry driven research; the development of a technology data base; and the development of commercial space transportation and infrastructure. The second phase includes the development of these technologies by industry for new commercial markets, and features unique industry/government collaborations such as Joint Endeavor Agreements. The final phase will feature technical applications actually brought to the marketplace. The government's role will be to support industry required infrastructure to encourage start-up markets and industries through follow-on development agreements such as the Space Systems Development Agreement. The Office of Commercial Programs has an aggressive flight program underway on the Space Shuttle, suborbital rockets, orbital expendable launch vehicles, and the Commercial Middeck Accommodation Module with SPACEHAB Inc. The Office of Commercial Program's has been allocated 35 percent of the U.S. share of the Space Station Freedom resources for 1997 utilization. A utilization plan has been developed with the Centers for the Commercial Development of Space and has identified eleven materials processing and biotechnology payloads occupying 5 double racks in the pressurized module as well as two payloads external to the module in materials exposure and environment monitoring. The Office of Commercial Programs will rely on the Space Station Freedom to provide the long duration laboratory component for space-based commercial research.

  16. Opportunities for Fluid Dynamics Research in the Forensic Discipline of Bloodstain Pattern Analysis

    NASA Astrophysics Data System (ADS)

    Attinger, Daniel; Moore, Craig; Donaldson, Adam; Jafari, Arian; Stone, Howard

    2013-11-01

    This review [Forensic Science International, vol. 231, pp. 375-396, 2013] highlights research opportunities for fluid dynamics (FD) studies related to the forensic discipline of bloodstain pattern analysis (BPA). The need for better integrating FD and BPA is mentioned in a 2009 report by the US National Research Council, entitled ``Strengthening Forensic Science in the United States: A Path Forward''. BPA aims for practical answers to specific questions of the kind: ``How did a bloodletting incident happen?'' FD, on the other hand, aims to quantitatively describe the transport of fluids and the related causes, with general equations. BPA typically solves the indirect problem of inspecting stains in a crime scene to infer the most probable bloodletting incident that produced these patterns. FD typically defines the initial and boundary conditions of a fluid system and from there describe how the system evolves in time and space, most often in a deterministic manner. We review four topics in BPA with strong connections to FD: the generation of drops, their flight, their impact and the formation of stains. Future research on these topics would deliver new quantitative tools and methods for BPA, and present new multiphase flow problems for FD.

  17. The HSCaRS Summer Enrichment Program; Research Opportunities for Minority and Women Undergraduates in Global Change Science

    NASA Technical Reports Server (NTRS)

    Estes, Jr., Maurice G.; Perkey, Donald J.; Coleman, T. L.

    1997-01-01

    The primary objective of the HSCaRS Summer Enrichment Program (SEP) is to make significant contributions to the NASA Mission to Planet Earth (MTPE) and the Alabama A&M University (AAMU) Center for Hydrology, Soil Climatology and Remote Sensing (HSCaRS) research missions by providing undergraduate student research internships with an emphasis on minority and women students. Additional objectives are to encourage more minority and women students to pursue advanced degrees in Earth system and global change science and to increase the participation of minority institutions in the U.S. Global Change Research Program. Also, the SEP strives to make students in the traditional science disciplines more aware of the opportunities in Earth System Science. In designing the SEP, it was acknowledged that HSCaRS was a new research effort and Center. Consequently, students were not expected to immediately recognize the Center as one would older, more established research laboratories with national reputations, such as Los Alamos, Battelle, National Consortium for Atmospheric Research (NCAR), etc. Yet we still wanted to compete nationally for the best students. Therefore, we designed the program with a competitive financial package that includes a stipend of $400 per week, round-trip transportation from home to the summer research site, and free campus housing and meal plans provided by Alabama A&M University. Students also received a modest living allowance of approximately $25 per week. The internship program was 10 weeks in residence at Alabama A&M University or IGCRE, and gave students the opportunity to select from six general research areas: micro-meteorology, soil data analysis, soil moisture modeling, instrumentation, geographic information systems, and computer science. Student participants also enrolled in an introductory global change science course as part of the summer program (a copy of the course outline is in the appendix). The program included participation in a

  18. Crowdsourcing in biomedicine: challenges and opportunities.

    PubMed

    Khare, Ritu; Good, Benjamin M; Leaman, Robert; Su, Andrew I; Lu, Zhiyong

    2016-01-01

    The use of crowdsourcing to solve important but complex problems in biomedical and clinical sciences is growing and encompasses a wide variety of approaches. The crowd is diverse and includes online marketplace workers, health information seekers, science enthusiasts and domain experts. In this article, we review and highlight recent studies that use crowdsourcing to advance biomedicine. We classify these studies into two broad categories: (i) mining big data generated from a crowd (e.g. search logs) and (ii) active crowdsourcing via specific technical platforms, e.g. labor markets, wikis, scientific games and community challenges. Through describing each study in detail, we demonstrate the applicability of different methods in a variety of domains in biomedical research, including genomics, biocuration and clinical research. Furthermore, we discuss and highlight the strengths and limitations of different crowdsourcing platforms. Finally, we identify important emerging trends, opportunities and remaining challenges for future crowdsourcing research in biomedicine. Published by Oxford University Press 2015. This work is written by US Government employees and is in the public domain in the US.

  19. Identifying Opportunities for Vertical Integration of Biochemistry and Clinical Medicine.

    PubMed

    Wendelberger, Karen J.; Burke, Rebecca; Haas, Arthur L.; Harenwattananon, Marisa; Simpson, Deborah

    1998-01-01

    Objectives: Retention of basic science knowledge, as judged by National Board of Medical Examiners' (NBME) data, suffers due to lack of apparent relevance and isolation of instruction from clinical application, especially in biochemistry. However, the literature reveals no systematic process for identifying key biochemical concepts and associated clinical conditions. This study systematically identified difficult biochemical concepts and their common clinical conditions as a critical step towards enhancing relevance and retention of biochemistry.Methods: A multi-step/ multiple stakeholder process was used to: (1) identify important biochemistry concepts; (2) determine students' perceptions of concept difficulty; (3) assess biochemistry faculty, student, and clinical teaching scholars' perceived relevance of identified concepts; and (4) identify associated common clinical conditions for relevant and difficult concepts. Surveys and a modified Delphi process were used to gather data, subsequently analyzed using SPSS for Windows.Results: Sixteen key biochemical concepts were identified. Second year medical students rated 14/16 concepts as extremely difficult while fourth year students rated nine concepts as moderately to extremely difficult. On average, each teaching scholar generated common clinical conditions for 6.2 of the 16 concepts, yielding a set of seven critical concepts and associated clinical conditions.Conclusions: Key stakeholders in the instructional process struggle to identify biochemistry concepts that are critical, difficult to learn and associated with common clinical conditions. However, through a systematic process beginning with identification of concepts and associated clinical conditions, relevance of basic science instruction can be enhanced.

  20. Research Opportunities in Information Science and Technology: Cognitive Aspects of Information Science, Information Technology, and Economics of Information.

    ERIC Educational Resources Information Center

    National Science Foundation. Washington, DC. Div. of Information Science and Technology.

    This volume contains the reports of three working groups which were convened separately over a 3-year period at the request of the Advisory Committee for the Division of Information Science and Technology of the National Science Foundation to obtain the opinion of experts concerning research opportunities and trends in information science and…

  1. Dissemination and Implementation Science in Primary Care Research and Practice: Contributions and Opportunities.

    PubMed

    Holtrop, Jodi Summers; Rabin, Borsika A; Glasgow, Russell E

    2018-01-01

    Dissemination and Implementation Science (DIS) is a growing research field that seeks to inform how evidence-based interventions can be successfully adopted, implemented, and maintained in health care delivery and community settings. In this article, an overview of DIS and how it has contributed to primary care delivery improvement, future opportunities for its use, and DIS resources for learning are described. Case examples are provided to illustrate how DIS can be used to solve the complex implementation and dissemination problems that emerge in primary care. Finally, recommendations are made to guide the use of DIS to inform and drive improvements in primary care delivery. © Copyright 2018 by the American Board of Family Medicine.

  2. Stakeholder engagement opportunities in systematic reviews: knowledge transfer for policy and practice.

    PubMed

    Keown, Kiera; Van Eerd, Dwayne; Irvin, Emma

    2008-01-01

    Knowledge transfer and exchange is the process of increasing the awareness and use of research evidence in policy or practice decision making by nonresearch audiences or stakeholders. One way to accomplish this end is through ongoing interaction between researchers and interested nonresearch audiences, which provides an opportunity for the two groups to learn more about one another. The purpose of this article is to describe and discuss various stakeholder engagement opportunities that we employ throughout the stages of conducting a systematic review, to increase knowledge utilization within these audiences. Systematic reviews of the literature on a particular topic can provide an unbiased overview of the state of the literature. The engagement opportunities we have identified are topic consultation, feedback meetings during the review, member of review team, and involvement in dissemination. The potential benefits of including stakeholders in the process of a systematic review include increased relevance, clarity, and awareness of systematic review findings. A further benefit is the potential for increased dissemination of the findings. Challenges that researchers face are that stakeholder interactions can be time- and resource-intensive, it can be difficult balancing stakeholder desires with scientific rigor, and stakeholders may have difficulties accepting findings with which they do not agree. Despite these challenges we have included stakeholder involvement as a permanent step in the procedure of conducting a systematic review.

  3. Identifying emerging issues in forestry as a tool for research planning.

    Treesearch

    Hans M. Gregersen; Allen L. Lundgren; Pamela J. Jakes; David N. Bengston

    1989-01-01

    A Delphi exercise is used to identify emerging issues in National Forest management and use, the relative importance of the issues, and barriers to resolving issues. USDA Forest Service managers agree on the importance of the 11 issues identified; however, researchers and National Forest managers do not always agree on the importance of issues or barriers.

  4. The ecological research needs of business.

    PubMed

    Armsworth, Paul R; Armsworth, Anastasia N; Compton, Natalie; Cottle, Phil; Davies, Ian; Emmett, Bridget A; Fandrich, Vanessa; Foote, Matthew; Gaston, Kevin J; Gardiner, Phil; Hess, Tim; Hopkins, John; Horsley, Nick; Leaver, Natasha; Maynard, Trevor; Shannon, Delia

    2010-04-01

    Businesses have an unrivalled ability to mobilize human, physical and financial capital, often manage large land holdings, and draw on resources and supply products that impact a wide array of ecosystems. Businesses therefore have the potential to make a substantial contribution to arresting declines in biodiversity and ecosystem services. To realize this potential, businesses require support from researchers in applied ecology to inform how they measure and manage their impacts on, and opportunities presented to them by, biodiversity and ecosystem services.We reviewed papers in leading applied ecology journals to assess the research contribution from existing collaborations involving businesses. We reviewed applications to, and grants funded by, the UK's Natural Environment Research Council for evidence of public investment in such collaborations. To scope opportunities for expanding collaborations with businesses, we conducted workshops with three sectors (mining and quarrying, insurance and manufacturing) in which participants identified exemplar ecological research questions of interest to their sector.Ten to fifteen per cent of primary research papers in Journal of Applied Ecology and Ecological Applications evidenced business involvement, mostly focusing on traditional rural industries (farming, fisheries and forestry). The review of UK research council funding found that 35% of applications mentioned business engagement, while only 1% of awarded grants met stricter criteria of direct business involvement.Some questions identified in the workshops aim to reduce costs from businesses' impacts on the environment and others to allow businesses to exploit new opportunities. Some questions are designed to inform long-term planning undertaken by businesses, but others would have more immediate commercial applications. Finally, some research questions are designed to streamline and make more effective those environmental policies that affect businesses

  5. The ecological research needs of business

    PubMed Central

    Armsworth, Paul R; Armsworth, Anastasia N; Compton, Natalie; Cottle, Phil; Davies, Ian; Emmett, Bridget A; Fandrich, Vanessa; Foote, Matthew; Gaston, Kevin J; Gardiner, Phil; Hess, Tim; Hopkins, John; Horsley, Nick; Leaver, Natasha; Maynard, Trevor; Shannon, Delia

    2010-01-01

    Businesses have an unrivalled ability to mobilize human, physical and financial capital, often manage large land holdings, and draw on resources and supply products that impact a wide array of ecosystems. Businesses therefore have the potential to make a substantial contribution to arresting declines in biodiversity and ecosystem services. To realize this potential, businesses require support from researchers in applied ecology to inform how they measure and manage their impacts on, and opportunities presented to them by, biodiversity and ecosystem services. We reviewed papers in leading applied ecology journals to assess the research contribution from existing collaborations involving businesses. We reviewed applications to, and grants funded by, the UK’s Natural Environment Research Council for evidence of public investment in such collaborations. To scope opportunities for expanding collaborations with businesses, we conducted workshops with three sectors (mining and quarrying, insurance and manufacturing) in which participants identified exemplar ecological research questions of interest to their sector. Ten to fifteen per cent of primary research papers in Journal of Applied Ecology and Ecological Applications evidenced business involvement, mostly focusing on traditional rural industries (farming, fisheries and forestry). The review of UK research council funding found that 35% of applications mentioned business engagement, while only 1% of awarded grants met stricter criteria of direct business involvement. Some questions identified in the workshops aim to reduce costs from businesses’ impacts on the environment and others to allow businesses to exploit new opportunities. Some questions are designed to inform long-term planning undertaken by businesses, but others would have more immediate commercial applications. Finally, some research questions are designed to streamline and make more effective those environmental policies that affect businesses

  6. Development of a framework to identify research gaps from systematic reviews.

    PubMed

    Robinson, Karen A; Saldanha, Ian J; McKoy, Naomi A

    2011-12-01

    Our objective was to develop a framework to identify research gaps from systematic reviews. We reviewed the practices of (1) evidence-based practice centers (EPCs), and (2) other organizations that conduct evidence syntheses. We developed and pilot tested a framework for identifying research gaps. Four (33%) EPCs and three (8%) other organizations reported using an explicit framework to determine research gaps. Variations of the PICO (population, intervention, comparison, outcomes) framework were most common. We developed a framework incorporating both the characterization of the gap using PICOS elements (also including setting) and the identification of the reason(s) why the gap exists as (1) insufficient or imprecise information, (2) biased information, (3) inconsistency or unknown consistency, and (4) not the right information. We mapped each of these reasons to concepts from three common evidence-grading systems. Our framework determines from systematic reviews where the current evidence falls short and why or how the evidence falls short. This explicit identification of research gaps will allow systematic reviews to maximally inform the types of questions that need to be addressed and the types of studies needed to address the research gaps. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. CIRIR Programs: Drilling and Research Opportunities at the Rochechouart Impact Structure

    NASA Technical Reports Server (NTRS)

    Lambert, P.; Alwmark, C.; Baratoux, D.; Brack, A.; Bruneton, P.; Buchner, E.; Claeys, P.; Dence, M.; French, B.; Hoerz, F

    2017-01-01

    Owing to its size, accessibility and erosional level, the Rochechouart impact structure, dated at 203 +/- 2 Ma (recalc.), is a unique reser-voir of knowledge within the population of the rare terrestrial analogous to large impacts craters observed on planetary surfaces. The site gives direct access to fundamental mechanisms both in impact-related geology (origin and evolution of planets) and biology (habitability of planets, emergence and evolution of life). For the last decade P. Lambert has been installing Rochechouart as International Natural Laboratory for studying impact processes and collateral effects on planetary surfaces. For this purpose the Center for International Research on Impacts and on Rochechouart (CIRIR) was installed on site in 2016 with twofold objectives and activities. First ones are scientific and dedicated to the scientific community. The second are cultural and educational and are dedi-cated to the public sensu lato. We present here the CIRIR, its scientific programs and the related reseach opportunities.

  8. Housing as a socio-economic determinant of health: findings of a national needs, gaps and opportunities assessment.

    PubMed

    Dunn, James R; Hayes, Michael V; Hulchanski, J David; Hwang, Stephen W; Potvin, Louise

    2006-01-01

    In 2002-2003, a Needs, Gaps and Opportunities Assessment (NGOA) was conducted to investigate relationships between socio-economic dimensions of housing and health. Recent reviews of the literature point to a dearth of research on the socio-economic dimensions of housing and health, despite its potential for promoting health. The NGOA sought to identify research needs and gaps, and future opportunities for research in housing, socio-economic status and health. The methods used included a literature scan, a scan of research capacity, eight regional stakeholder workshops across Canada, and an open-ended e-mail survey of stakeholders. In this paper, we report the findings of the stakeholder consultations. The main finding of the NGOA was that there is a significant dearth of research on housing as a socio-economic determinant of health but enormous potential for conducting high-impact, longitudinal and quasi-experimental research in the area. Of particular interest to stakeholder participants in the NGOA were the economic aspects of housing and health; the impact of housing on health for vulnerable subgroups (e.g., Aboriginal peoples, immigrants, children, seniors); the role of socio-economically and ethnically mixed communities; and the interaction between socio-economic aspects of housing and biophysical hazards in the home. The NGOA demonstrated that there is a substantial audience eager for knowledge on housing as a socio-economic determinant of health and that such knowledge could make an immediate impact on policy decision-making and program operation. Although knowledge gaps are substantial, the NGOA clearly identifies opportunities for high-impact, longitudinal and quasi-experimental research. Recently signed federal-provincial funding agreements for housing make the findings of the NGOA timely. Moreover, the NGOA results demonstrate how research on housing as a socio-economic determinant of health could be a strategy for improving our understanding of the

  9. Equal Educational Opportunity?

    ERIC Educational Resources Information Center

    Morris, Lorenzo

    1980-01-01

    Holds that the "Bakke" decision simply reaffirmed an insufficient commitment to equal opportunities for Blacks in higher education. Reviews several studies, including research conducted at the Institute for the Study of Educational Policy (ISEP) that has focused on the social and economic context of educational discrimination. (GC)

  10. Young Investigators: Concerns, Options, and Opportunities. AIR Forum 1979 Paper.

    ERIC Educational Resources Information Center

    Trumble, Robert R.

    Declining opportunities for young researchers at universities and proposals to improve the situation are discussed. Concerns related to opportunities for young researchers include: (1) the leveling-off of student enrollments at universities; (2) the fact that tenure limits faculty turnover; (3) possible effects on research if the age distribution…

  11. Facilitating mental health research for patients, clinicians and researchers: a mixed-method study.

    PubMed

    Robotham, D; Waterman, S; Oduola, S; Papoulias, C; Craig, T; Wykes, T

    2016-08-08

    Research registers using Consent for Contact (C4C) can facilitate recruitment into mental health research studies, allowing investigators to contact patients based on clinical records information. We investigated whether such a register was useful for mental health research, seeking the perspectives of patients and research investigators. In 2012, a C4C register was developed in a large secondary mental health provider within the UK; almost 9000 patients have joined. This mixed-method study audited the effectiveness of the register. A 'mystery shopper' exercise was conducted, and patients (n=21) were recruited to ask clinicians about the availability of research opportunities. Structured interviews were conducted with patients (n=52) about their experiences of being on the register. Similar interviews were conducted with 18 investigators from 19 studies, who had attempted to use the register to recruit participants. The impact of C4C on study recruitment, and whether it helped patients learn about research. So far, the register has provided 928 individuals with 1085 research opportunities (in 60% of cases, the individual agreed to participate in the study). Clinicians were willing to link patients to research opportunities, but often lacked information about studies. For patients, the register provided opportunities which they may not otherwise have; 27 of 52 had participated in studies since joining the register (18 participating for the first time). Most investigators used the register to supplement recruitment to their studies, but described problems in prescreening potential participants from a clinical record for complex studies. Although the register helped investigators recruit for studies, and provided patients with research opportunities, clinicians' input is still useful for identifying suitable participants. C4C registers should be adapted to provide clinicians with automatically updated information on local studies allowing them to match patients on

  12. A practical guideline for identifying research intent with projects that collect private, identifiable health information.

    PubMed

    Amdur, Robert J; Speers, Marjorie A

    2003-06-01

    Radiation oncologists frequently engage in activities that involve the collection and analysis of data from medical records. Access to health information is an ethical issue because, if not done according to appropriate guidelines, it constitutes an invasion of privacy or breach in confidentiality. To protect patients for the social harm that may result from medical record review, our society has established laws and regulations that apply to projects that require medical record review. A major branch point in the guidelines for such projects is whether private information will be collected for research or nonresearch purposes. However, a problem with discussing privacy protection in terms of a research versus nonresearch model is that it is difficult to make this distinction for many kinds of projects. The purpose of this paper is to establish a practical guideline that can be used to decide if a project that involves analysis of private, identifiable medical information should be considered research from the regulatory standpoint.

  13. The NASA Short-Term Prediction Research and Transition (SPoRT) Center: Opportunities for Collaboration in the Great Lakes Region

    NASA Technical Reports Server (NTRS)

    Molthan, Andrew L.

    2010-01-01

    The presentation slides include: The SPoRT Center, History and Future of SPoRT, Great Lakes Applications, Great Lakes Forecasting Issues, Applications to the WRF-EMS, Precipitation Science, Lake Effect Precipitation, Sensitivity to Microphysics, Exploring New Schemes, Opportunities for Collaboration, and SPoRT Research and Development.

  14. Opportunities and methodological challenges in EEG and MEG resting state functional brain network research.

    PubMed

    van Diessen, E; Numan, T; van Dellen, E; van der Kooi, A W; Boersma, M; Hofman, D; van Lutterveld, R; van Dijk, B W; van Straaten, E C W; Hillebrand, A; Stam, C J

    2015-08-01

    Electroencephalogram (EEG) and magnetoencephalogram (MEG) recordings during resting state are increasingly used to study functional connectivity and network topology. Moreover, the number of different analysis approaches is expanding along with the rising interest in this research area. The comparison between studies can therefore be challenging and discussion is needed to underscore methodological opportunities and pitfalls in functional connectivity and network studies. In this overview we discuss methodological considerations throughout the analysis pipeline of recording and analyzing resting state EEG and MEG data, with a focus on functional connectivity and network analysis. We summarize current common practices with their advantages and disadvantages; provide practical tips, and suggestions for future research. Finally, we discuss how methodological choices in resting state research can affect the construction of functional networks. When taking advantage of current best practices and avoid the most obvious pitfalls, functional connectivity and network studies can be improved and enable a more accurate interpretation and comparison between studies. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  15. 'Ecosystem service opportunities': A practice-oriented framework for identifying economic instruments to enhance biodiversity and human livelihoods.

    PubMed

    Rode, Julian; Wittmer, Heidi; Emerton, Lucy; Schröter-Schlaack, Christoph

    2016-09-01

    Economic instruments that promise "win-win" solutions for both biodiversity conservation and human livelihoods have become increasingly popular over recent years. There however remains a gap in terms of practical and policy-relevant guidance about appropriate approaches that take into account the local needs and the specific cultural, legal, and ecological context in which such instruments are being developed and applied. This paper presents a step-by-step framework that helps conservation and development planners and practitioners to identify economic instruments that can promote pro-conservation behaviour in a specific setting. The concept of 'ecosystem service opportunities' builds on, and brings together, general economic principles and an ecosystem services perspective. The framework was designed to also address a number of concerns regarding economic approaches in order to help practitioners recognise the potentials and limits of economic approaches to nature conservation. The framework is illustrated by its application within the realm of a biodiversity conservation project in Thailand.

  16. Managing Watersheds as Couple Human-Natural Systems: A Review of Research Opportunities

    NASA Astrophysics Data System (ADS)

    Cai, X.

    2011-12-01

    evidenced by 1) institutional innovation for integrated watershed management; 2) real-world management practices involving multidisciplinary expertise; 3) growing role of economics in systems analysis; 4) enhanced research programs such as the CHNS program and Water, Sustainability and Climate (WSC) program at the US National Science Foundation (NSF). Furthermore, recent scientific and technological developments are expected to accommodate integrated watershed system analysis approaches, such as: 1) increasing availability of distributed digital datasets especially from remote sensing products (e.g. digital watersheds); 2) distributed and semi-distributed watershed hydrologic modeling; 3) enhanced hydroclimatic monitoring and forecast; 4) identified evidences of vulnerability and threshold behavior of watersheds; and 5) continuing improvements in computational and optimization algorithms. Managing watersheds as CHNS will be critical for watershed sustainability, which ensures that human societies will benefit forever from the watershed through development of harmonious relationships between human and natural systems. This presentation will provide a review of the research opportunities that take advantage of the concept of CHNS and associated scientific, technological and institutional innovations/developments.

  17. Ethical Considerations for Educational Research in a Virtual World

    ERIC Educational Resources Information Center

    Girvan, C.; Savage, T.

    2012-01-01

    The combination of features in virtual worlds provides an opportunity to implement and research unique learning experiences. With increasing interest and activity from the educational research community, exploring virtual worlds for teaching and learning, there is a need to identify and understand the ethical implications of conducting research in…

  18. Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26-27 June 2013, Research Triangle Park, NC, USA.

    PubMed

    Hendrickx, Diana M; Boyles, Rebecca R; Kleinjans, Jos C S; Dearry, Allen

    2014-12-01

    A joint US-EU workshop on enhancing data sharing and exchange in toxicogenomics was held at the National Institute for Environmental Health Sciences. Currently, efficient reuse of data is hampered by problems related to public data availability, data quality, database interoperability (the ability to exchange information), standardization and sustainability. At the workshop, experts from universities and research institutes presented databases, studies, organizations and tools that attempt to deal with these problems. Furthermore, a case study showing that combining toxicogenomics data from multiple resources leads to more accurate predictions in risk assessment was presented. All participants agreed that there is a need for a web portal describing the diverse, heterogeneous data resources relevant for toxicogenomics research. Furthermore, there was agreement that linking more data resources would improve toxicogenomics data analysis. To outline a roadmap to enhance interoperability between data resources, the participants recommend collecting user stories from the toxicogenomics research community on barriers in data sharing and exchange currently hampering answering to certain research questions. These user stories may guide the prioritization of steps to be taken for enhancing integration of toxicogenomics databases.

  19. Setting Priorities for Diabetic Retinopathy Clinical Research and Identifying Evidence Gaps.

    PubMed

    Le, Jimmy T; Hutfless, Susan; Li, Tianjing; Bressler, Neil M; Heyward, James; Bittner, Ava K; Glassman, Adam; Dickersin, Kay

    2017-01-01

    Prioritizing comparative effectiveness research may contribute to obtaining answers that clinicians perceive they need and may minimize research that could be considered wasteful. Our objective was to identify evidence gaps and set priorities for new systematic reviews and randomized controlled trials for managing diabetic retinopathy (DR), including diabetic macular edema (DME). Cross-sectional study. Diabetic Retinopathy Clinical Research Network (DRCR.net) investigators. We provided recommendations from the American Academy of Ophthalmology's 2012 Preferred Practice Patterns for Diabetic Retinopathy as 91 answerable clinical research questions about intervention effectiveness to 410 DRCR.net investigators to rate each question's importance from 0 (not important) to 10 (very important) using a 2-round Delphi survey and to suggest additional questions. We considered questions as high priority if at least 75% of respondents to both rounds assigned an importance rating of 5 or more in round 2. We also extracted outcome measures relevant to DR and asked respondents to identify those that must be measured in all studies. We mapped Cochrane reviews published up to March 2016 to high-priority clinical research questions. Ranking of importance of each clinical question. Thirty-two individuals completed rounds 1 and 2 and suggested 15 questions. Among the final list of 106 clinical research questions, 22 questions met our definition of high priority: 9 of 22 concerned the effectiveness of anti-VEGF therapy, and 13 of 22 focused on how often patients should be followed up (re-examination) and treatment effectiveness in patients with specific characteristics (e.g., DME). Outcomes that 75% or more of respondents marked as "must be measured in all studies" included visual acuity and visual loss, death of participants, and intraocular pressure. Only 1 prioritized question was associated with conclusive evidence from a Cochrane systematic review. A limited response rate among

  20. Advancing HIV research with pregnant women: navigating challenges and opportunities.

    PubMed

    Krubiner, Carleigh B; Faden, Ruth R; Cadigan, R Jean; Gilbert, Sappho Z; Henry, Leslie M; Little, Margaret O; Mastroianni, Anna C; Namey, Emily E; Sullivan, Kristen A; Lyerly, Anne D

    2016-09-24

    Concerns about including pregnant women in research have led to a dearth of evidence to guide safe and effective treatment and prevention of HIV in pregnancy. To better understand why these evidence gaps persist and inform guidance for responsible inclusion of pregnant women in the HIV research agenda, we aimed to learn what HIV experts perceive as barriers and constraints to conducting this research. We conducted a series of group and one-on-one consultations with 62 HIV investigators and clinicians to elicit their views and experiences conducting HIV research involving pregnant women. Thematic analysis was used to identify priorities and perceived barriers to HIV research with pregnant women. Experts discussed a breadth of needed research, including safety, efficacy, and appropriate dosing of: newer antiretrovirals for pregnant women, emerging preventive strategies, and treatment for coinfections. Challenges to conducting research on pregnancy and HIV included ethical concerns, such as how to weigh risks and benefits in pregnancy; legal concerns, such as restrictive interpretations of current regulations and liability issues; financial and professional disincentives, including misaligned funder priorities and fear of reputational damage; and analytical and logistical complexities, such as challenges recruiting and retaining pregnant women to sufficiently power analyses. Investigators face numerous challenges to conducting needed HIV research with pregnant women. Advancing such research will require clearer guidance regarding ethical and legal uncertainties; incentives that encourage rather than discourage investigators to undertake such research; and a commitment to earlier development of safety and efficacy data through creative trial designs.

  1. Inside the Green House "Black Box": Opportunities for High-Quality Clinical Decision Making.

    PubMed

    Bowers, Barbara; Roberts, Tonya; Nolet, Kimberly; Ryther, Brenda

    2016-02-01

    To develop a conceptual model that explained common and divergent care processes in Green House (GH) nursing homes with high and low hospital transfer rates. Eighty-four face-to-face, semistructured interviews were conducted with direct care, professional, and administrative staff with knowledge of care processes in six GH organizations in six states. The qualitative grounded theory method was used for data collection and analysis. Data were analyzed using open, axial, and selective coding. Data collection and analysis occurred iteratively. Elements of the GH model created significant opportunities to identify, communicate, and respond to early changes in resident condition. Staff in GH homes with lower hospital transfer rates employed care processes that maximized these opportunities. Staff in GH homes with higher transfer rates failed to maximize, or actively undermined, these opportunities. Variations in how the GH model was implemented across GH homes suggest possible explanations for inconsistencies found in past research on the care outcomes, including hospital transfer rates, in culture change models. The findings further suggest that the details of culture change implementation are important considerations in model replication and policies that create incentives for care improvements. © Health Research and Educational Trust.

  2. Seizing Opportunity: "Opportunity as Transformation"

    ERIC Educational Resources Information Center

    Williams, Michael; Muller, Esther

    2012-01-01

    Opportunity creates conditions for achievement. We learn daily of the success of others that resulted from conditions they created through opportunity. Often these conditions of opportunity are the product of a compelling vision of a future steeped in possibility and rich in reward. These visions, however, must be operationalized in order to be…

  3. Building an Australasian paramedicine research agenda: a narrative review.

    PubMed

    O'Meara, Peter; Maguire, Brian; Jennings, Paul; Simpson, Paul

    2015-12-15

    The need for paramedicine research has been recognised internationally through efforts to develop out-of-hospital research agendas in several developed countries. Australasia has a substantial paramedicine research capacity compared to the discipline internationally and is well positioned as a potential leader in the drive towards evidence-based policy and practice in paramedicine. Our objective was to draw on international experiences to identify and recommend the best methodological approach that should be employed to develop an Australasian paramedicine research agenda. A search and critical appraisal process was employed to produce an overview of the literature related to the development of paramedicine research agendas throughout the world. Based on these international experiences, and our own analysis of the Australasian context, we recommend that a mixed methods approach be used to develop an inclusive Australasian Paramedicine Research Agenda. This approach will capture the views and interests of a wide range of expert stakeholders through multiple data collection strategies, including interviews, roundtable discussions and an online Delphi consensus survey. Paramedic researchers and industry leaders have the opportunity to use this multidisciplinary process of inquiry to develop a paramedicine research agenda that will provide a framework for the development of a culture of open evaluation, innovation and improvement. This research agenda would assess the progress of paramedicine research in Australia and New Zealand, map the research capacity of the paramedicine discipline, paramedic services, universities and professional organisations, identify current strengths and opportunities, make recommendations to capitalize on opportunities, and identify research priorities. Success will depend on ensuring the participation of a representative sample of expert stakeholders, fostering an open and collaborative roundtable discussion, and adhering to a predefined

  4. Invited article: Neurology education research.

    PubMed

    Stern, Barney J; Lowenstein, Daniel H; Schuh, Lori A

    2008-03-11

    There is a need to rigorously study the neurologic education of medical students, neurology residents, and neurologists to determine the effectiveness of our educational efforts. We review the status of neurologic education research as it pertains to the groups of interest. We identify opportunities and impediments for education research. The introduction of the Accreditation Council for Graduate Medical Education core competencies, the Accreditation Council of Continuing Medical Education requirement to link continuing medical education to improved physician behavior and patient care, and the American Board of Medical Specialties/American Board of Psychiatry and Neurology-mandated maintenance of certification program represent research opportunities. Challenges include numerous methodologic issues such as definition of the theoretical framework of the study, adequate sample size ascertainment, and securing research funding. State-of-the-art education research will require multidisciplinary research teams and innovative funding strategies. The central goal of all concerned should be defining educational efforts that improve patient outcomes.

  5. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oldenburg, Curtis; Oldenburg, Curtis M.; Torn, Margaret S.

    2008-03-21

    Fossil fuel combustion, deforestation, and biomass burning are the dominant contributors to increasing atmospheric carbon dioxide (CO{sub 2}) concentrations and global warming. Many approaches to mitigating CO{sub 2} emissions are being pursued, and among the most promising are terrestrial and geologic carbon sequestration. Recent advances in ecology and microbial biology offer promising new possibilities for enhancing terrestrial and geologic carbon sequestration. A workshop was held October 29, 2007, at Lawrence Berkeley National Laboratory (LBNL) on Biologically Enhanced Carbon Sequestration (BECS). The workshop participants (approximately 30 scientists from California, Illinois, Oregon, Montana, and New Mexico) developed a prioritized list of researchmore » needed to make progress in the development of biological enhancements to improve terrestrial and geologic carbon sequestration. The workshop participants also identified a number of areas of supporting science that are critical to making progress in the fundamental research areas. The purpose of this position paper is to summarize and elaborate upon the findings of the workshop. The paper considers terrestrial and geologic carbon sequestration separately. First, we present a summary in outline form of the research roadmaps for terrestrial and geologic BECS. This outline is elaborated upon in the narrative sections that follow. The narrative sections start with the focused research priorities in each area followed by critical supporting science for biological enhancements as prioritized during the workshop. Finally, Table 1 summarizes the potential significance or 'materiality' of advances in these areas for reducing net greenhouse gas emissions.« less

  6. An opportune and unique research to evaluate the public health impact of electronic cigarettes.

    PubMed

    Besaratinia, Ahmad; Tommasi, Stella

    2017-10-01

    In response to the growing public health concern regarding the risks or benefits of electronic cigarettes (e-cig) use relative to smoking, the National Institute on Drug Abuse (NIDA) has recently introduced the first standardized- and well- characterized e-cig device to the research community (see, https://www.drugabuse.gov/funding/supplemental-information-nida-e-cig ). E-cig are promoted as safe alternatives to conventional tobacco cigarettes and/or as aides to smoking cessation. E-cig are highly popular among cigarette smokers who are unable/unwilling to quit but are willing to switch to putatively less-harmful tobacco substitutes. E-cig are also becoming increasingly popular among youth who have never experimented with combustible cigarettes. However, chemical analyses of e-cig juices (both in liquid form and after being heated into vapor) have shown that many carcinogens present in cigarette smoke are also found in a range of e-cig products. To date, the cancer-causing potential of e-cig has not been investigated in e-cig users (i.e., vapers). Use of e-cig without a prior history of smoking is currently a rare phenomenon in adults, but is increasingly common among youth. Consequently, investigating the carcinogenic potential of e-cig in nonsmoking youth provides a unique opportunity to verify the health impact of e-cig use, without the confounding effects of cigarette smoking. Within this context, the availability of the NIDA Standard Research e-cig offers a unique research opportunity with tremendous public health implications. Comparing and contrasting the cancer-causing potentials of standard vaping and smoking in youth will help determine the health risks or benefits of e-cig use relative to cigarette smoking. This information will be instrumental in making scientifically based decisions on the development and evaluation of policies and regulations on e-cig manufacture, marketing, and distribution. Ultimately, evidence-based guidelines and legislations on e

  7. The Prevalence of Stalking among College Students: The Disparity between Researcher- and Self-Identified Victimization

    ERIC Educational Resources Information Center

    McNamara, Corinne L.; Marsil, Dorothy F.

    2012-01-01

    Objective: Researchers examined the prevalence of self-identified and researcher-identified stalking victimization among college students. Participants and Methods: A representative sample of 1,573 (70.1% female; 29.9% male) student respondents completed an online stalking questionnaire. Results: Overall, 12% self-identified as having been…

  8. Ecologic Momentary Assessment: Perspectives on Applications and Opportunities in Research and Practice Regarding Nutrition Behaviors.

    PubMed

    Hand, Rosa K; Perzynski, Adam T

    2016-09-01

    Retrospective self-reported data have limitations, making it important to evaluate alternative forms of measurement for nutrition behaviors. Ecological momentary assessment (EMA) attempts to overcome the challenges of recalled data with real-time data collection in a subject's natural environment, often leveraging technology. This perspective piece 1) introduces the concepts and terminology of EMA, 2) provides an overview of the methodological and analytical considerations, 3) gives examples of past research using EMA, and 4) suggests new opportunities (including combining assessment and intervention) and limitations (including the need for technology) for the application of EMA to research and practice regarding nutrition behaviors. Copyright © 2016 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  9. Using Twitter™ to drive research impact: A discussion of strategies, opportunities and challenges.

    PubMed

    Schnitzler, Katy; Davies, Nigel; Ross, Fiona; Harris, Ruth

    2016-07-01

    Researchers have always recognised the importance of disseminating the findings of their work, however, recently the need to proactively plan and drive the impact of those findings on the wider society has become a necessity. Firstly, this is because funders require evidence of return from investment and secondly and crucially because national research assessments are becoming powerful determinants of future funding. In research studies associated with nursing, impact needs to be demonstrated by showing the effect on a range of stakeholders including service users, patients, carers, the nursing workforce and commissioners. Engaging these groups is a well-known challenge influenced by lack of access to academic journals, lack of time to read long complex research papers and lack of opportunities to interact directly with the researchers. This needs to be addressed urgently to enable nursing research to increase the impact that it has on health delivery and the work of clinical practitioners. Social media is potentially a novel way of enabling research teams to both communicate about research as studies progress and to disseminate findings and research funders are increasingly using it to publicise information about research programmes and studies they fund. A search of the healthcare literature reveals that advice and guidance on the use of social media for research studies is not well understood or exploited by the research community. This paper, therefore, explores how using social networking platforms, notably Twitter™ offers potential new ways for communicating research findings, accessing diverse and traditionally hard-to-reach audiences, knowledge exchange at an exponential rate, and enabling new means of capturing and demonstrating research impact. The paper discusses approaches to initiate the setup of social networking platforms in research projects and considers the practical challenges of using Twitter™ in nursing and healthcare research. The

  10. Development and pilot test of a process to identify research needs from a systematic review.

    PubMed

    Saldanha, Ian J; Wilson, Lisa M; Bennett, Wendy L; Nicholson, Wanda K; Robinson, Karen A

    2013-05-01

    To ensure appropriate allocation of research funds, we need methods for identifying high-priority research needs. We developed and pilot tested a process to identify needs for primary clinical research using a systematic review in gestational diabetes mellitus. We conducted eight steps: abstract research gaps from a systematic review using the Population, Intervention, Comparison, Outcomes, and Settings (PICOS) framework; solicit feedback from the review authors; translate gaps into researchable questions using the PICOS framework; solicit feedback from multidisciplinary stakeholders at our institution; establish consensus among multidisciplinary external stakeholders on the importance of the research questions using the Delphi method; prioritize outcomes; develop conceptual models to highlight research needs; and evaluate the process. We identified 19 research questions. During the Delphi method, external stakeholders established consensus for 16 of these 19 questions (15 with "high" and 1 with "medium" clinical benefit/importance). We pilot tested an eight-step process to identify clinically important research needs. Before wider application of this process, it should be tested using systematic reviews of other diseases. Further evaluation should include assessment of the usefulness of the research needs generated using this process for primary researchers and funders. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. Office of Equal Opportunity Programs

    NASA Technical Reports Server (NTRS)

    Chin, Jennifer L.

    2004-01-01

    The NASA Glenn Office of Equal Opportunity Programs works to provide quality service for all programs and/or to assist the Center in becoming a model workplace. During the summer of 2004, I worked with Deborah Cotleur along with other staff members to create and modify customer satisfaction surveys. This office aims to assist in developing a model workplace by providing functions as a change agent to the center by serving as an advisor to management to ensure equity throughout the Center. In addition, the office serves as a mediator for the Center in addressing issues and concerns. Lastly, the office provides assistance to employees to enable attainment of personal and organizational goals. The Office of Equal Opportunities is a staff office which reports and provides advice to the Center Director and Executive Leadership, implements laws, regulations, and presidential executive orders, and provides center wide leadership and assistance to NASA GRC employees. Some of the major responsibilities of the office include working with the discrimination complaints program, special emphasis programs (advisory groups), management support, monitoring and evaluation, contract compliance, and community outreach. During my internship in this office, my main objective was to create four customer satisfaction surveys based on EO retreats, EO observances, EO advisory boards, and EO mediation/counseling. I created these surveys after conducting research on past events and surveys as well as similar survey research created and conducted by other NASA centers, program for EO Advisory group members, leadership training sessions for supervisors, preventing sexual harassment training sessions, and observance events. I also conducted research on the style and format from feedback surveys from the Marshall Equal Opportunity website, the Goddard website, and the main NASA website. Using the material from the Office of Equal Opportunity Programs at Glenn Research Center along with my

  12. Post discharge issues identified by a call-back program: identifying improvement opportunities.

    PubMed

    Ojeda, Patricia I; Kara, Areeba

    2017-12-01

    The period following discharge from the hospital is one of heightened vulnerability. Discharge instructions serve as a guide during this transition. Yet, clinicians receive little feedback on the quality of this document that ties into the patients' experience. We reviewed the issues voiced by discharged patients via a call-back program and compared them to the discharge instructions they had received. At our institution, patients receive an automated call forty-eight hours following discharge inquiring about progress. If indicated by the response to the call, they are directed to a nurse who assists with problem solving. We reviewed the nursing documentation of these encounters for a period of nine months. The issues voiced were grouped into five categories: communication, medications, durable medical equipment/therapies, follow up and new or ongoing symptoms. The discharge instructions given to each patient were reviewed. We retrieved data on the number of discharges from each specialty from the hospital over the same period. A total of 592 patients voiced 685 issues. The numbers of patients discharged from medical or surgical services identified as having issues via the call-back line paralleled the proportions discharged from medical and surgical services from the hospital during the same period. Nearly a quarter of the issues discussed had been addressed in the discharge instructions. The most common category of issues was related to communication deficits including missing or incomplete information which made it difficult for the patient to enact or understand the plan of care. Medication prescription related issues were the next most common. Resource barriers and questions surrounding medications were often unaddressed. Post discharge issues affect patients discharged from all services equally. Data from call back programs may provide actionable targets for improvement, identify the inpatient team's 'blind spots' and be used to provide feedback to clinicians.

  13. Opportunities for NASA Aerospace Related Funding and Collaboration

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2005-01-01

    This presentation describes the different opportunities that NASA offers for effective collaboration with Academia and Industry. In particular, the presentation includes a general overview of opportunities such as SBIRs, STTRs, Educational Programs and NASA Research Announcements. A general description of forthcoming competitive opportunities under the Exploration Systems Mission Directorate (ESMD) as well as the Science Mission Directorate (SMD) are also provided.

  14. Public participation GIS: a method for identifying ecosystems services

    USGS Publications Warehouse

    Brown, Greg; Montag, Jessica; Lyon, Katie

    2012-01-01

    This study evaluated the use of an Internet-based public participation geographic information system (PPGIS) to identify ecosystem services in Grand County, Colorado. Specific research objectives were to examine the distribution of ecosystem services, identify the characteristics of participants in the study, explore potential relationships between ecosystem services and land use and land cover (LULC) classifications, and assess the methodological strengths and weakness of the PPGIS approach for identifying ecosystem services. Key findings include: (1) Cultural ecosystem service opportunities were easiest to identify while supporting and regulatory services most challenging, (2) participants were highly educated, knowledgeable about nature and science, and have a strong connection to the outdoors, (3) some LULC classifications were logically and spatially associated with ecosystem services, and (4) despite limitations, the PPGIS method demonstrates potential for identifying ecosystem services to augment expert judgment and to inform public or environmental policy decisions regarding land use trade-offs.

  15. Marshall Space Flight Center Small Business Opportunities

    NASA Technical Reports Server (NTRS)

    Garrison, Lynn

    2007-01-01

    This viewgraph presentation reviews the small business opportunities that are available with the Marshall Space Flight Center. It includes information on all forms of opportunities available and information sources: subcontracting, websites, contacts and a separate section on Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) Programs

  16. Excessive workload, uncertain career opportunities and lack of funding are important barriers to recruiting and retaining primary care medical researchers: a qualitative interview study.

    PubMed

    Thomsen, Janus Laust; Jarbøl, Dorthe; Søndergaard, Jens

    2006-10-01

    Research activity in primary care has been steadily increasing, but is still insufficient and more researchers are needed. Many initiatives have been launched to recruit and retain primary care researchers, but only little is known about barriers and facilitators to a research career in primary care. To examine barriers and facilitators to recruiting and retaining primary care medical researchers. Semi-structured interviews with 33 primary care medical researchers, all medical doctors. We used a phenomenological approach to analysing the interviews. Important barriers to pursuing a research career in primary care were heavy workload, isolation at work, short-term funding and low salary. Important facilitators to attracting and retaining primary care researchers were the desire and opportunity to improve primary care, the flexible working conditions, the career opportunities, including the possibility of combining university-based research with clinical work and a friendly and competent research environment. Better strategies for recruiting and retaining researchers are a prerequisite for the development of primary care, and in future the main emphasis should be on working conditions, networking and mentoring. Studies including those primary care physicians who have chosen not to do research are highly needed.

  17. Strategies to design clinical studies to identify predictive biomarkers in cancer research.

    PubMed

    Perez-Gracia, Jose Luis; Sanmamed, Miguel F; Bosch, Ana; Patiño-Garcia, Ana; Schalper, Kurt A; Segura, Victor; Bellmunt, Joaquim; Tabernero, Josep; Sweeney, Christopher J; Choueiri, Toni K; Martín, Miguel; Fusco, Juan Pablo; Rodriguez-Ruiz, Maria Esperanza; Calvo, Alfonso; Prior, Celia; Paz-Ares, Luis; Pio, Ruben; Gonzalez-Billalabeitia, Enrique; Gonzalez Hernandez, Alvaro; Páez, David; Piulats, Jose María; Gurpide, Alfonso; Andueza, Mapi; de Velasco, Guillermo; Pazo, Roberto; Grande, Enrique; Nicolas, Pilar; Abad-Santos, Francisco; Garcia-Donas, Jesus; Castellano, Daniel; Pajares, María J; Suarez, Cristina; Colomer, Ramon; Montuenga, Luis M; Melero, Ignacio

    2017-02-01

    The discovery of reliable biomarkers to predict efficacy and toxicity of anticancer drugs remains one of the key challenges in cancer research. Despite its relevance, no efficient study designs to identify promising candidate biomarkers have been established. This has led to the proliferation of a myriad of exploratory studies using dissimilar strategies, most of which fail to identify any promising targets and are seldom validated. The lack of a proper methodology also determines that many anti-cancer drugs are developed below their potential, due to failure to identify predictive biomarkers. While some drugs will be systematically administered to many patients who will not benefit from them, leading to unnecessary toxicities and costs, others will never reach registration due to our inability to identify the specific patient population in which they are active. Despite these drawbacks, a limited number of outstanding predictive biomarkers have been successfully identified and validated, and have changed the standard practice of oncology. In this manuscript, a multidisciplinary panel reviews how those key biomarkers were identified and, based on those experiences, proposes a methodological framework-the DESIGN guidelines-to standardize the clinical design of biomarker identification studies and to develop future research in this pivotal field. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. Building community research capacity: process evaluation of community training and education in a community-based participatory research program serving a predominantly Puerto Rican community.

    PubMed

    Tumiel-Berhalter, Laurene M; McLaughlin-Diaz, Victoria; Vena, John; Crespo, Carlos J

    2007-01-01

    Education and training build community research capacity and have impact on improvements of health outcomes. This manuscript describes the training and educational approaches to building research capacity that were utilized in a community-based participatory research program serving a Puerto Rican population and identifies barriers and strategies for overcoming them. A process evaluation identified a multitiered approach to training and education that was critical to reaching the broad community. This approach included four major categories providing a continuum of education and training opportunities: networking, methods training, on-the-job experience, and community education. Participation in these opportunities supported the development of a registry, the implementation of a survey, and two published manuscripts. Barriers included the lack of a formal evaluation of the education and training components, language challenges that limited involvement of ethnic groups other than Puerto Ricans, and potential biases associated with the familiarity of the data collector and the participant. The CBPR process facilitated relationship development between the university and the community and incorporated the richness of the community experience into research design. Strategies for improvement include incorporating evaluation into every training and educational opportunity and developing measures to quantify research capacity at the individual and community levels. Evaluating training and education in the community allows researchers to quantify the impact of CBPR on building community research capacity.

  19. Equal Opportunities for Women.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France). Directorate for Manpower and Social Affairs.

    A study of the opportunities for women in member countries of the Organisation for Economic Cooperation and Development (OECD) is reported along with suggested policy directions for government programs. Focus is on identifying the gaps that have appeared or grown wider in recent decades between, on one hand, existing laws, policies, and…

  20. A qualitative exploration of the informed consent process in hematopoietic cell transplantation clinical research and opportunities for improvement.

    PubMed

    Raj, M; Choi, S W; Platt, J

    2017-02-01

    Informed consent (IC) struggles to meet the ethical principles it strives to embody in the context of hematopoietic cell transplantation (HCT). Patients often participate in multiple clinical trials making it difficult to effectively inform the participants and fulfill complex regulations. The recent Notice of Proposed Rule Making would make major changes to federal requirements, providing a timely opportunity to evaluate existing practice. Twenty health care professionals within a Midwest Academic Medical Center involved in obtaining IC in the HCT clinic or involved in patient care during or after the IC process were interviewed to understand: (1) how they approached the IC process; (2) how they described a 'successful' IC process; and (3) opportunities for innovation. Narrative and discourse analyses of interviews indicate that providers understand IC to be a collaborative process requiring engagement and participation of providers, patients and caregivers. 'Markers of success' were identified including cognitive, affective and procedural markers focusing on patient understanding and comfort with the decision to participate. Opportunities for innovating the process included use of decision aids and tablet-based technology, and better use of patient portals. Our findings suggest specific interventions for the IC process that could support the process of consent for providers, patients and caregivers.

  1. Educational preparation: Research in A&E.

    PubMed

    1996-02-01

    Just as there is an evergrowing number of educational opportunities for A&E (1), there is growing recognition of the importance of research in the development of the 'art and science' of nursing. In A&E nursing there is a need to develop the science of our specialty to further enhance the treatment and care of patients. This paper asks some fundamental questions about research and researchers in A&E and identifies key research priorities for the coming years.

  2. Leveraging electronic health records for clinical research.

    PubMed

    Raman, Sudha R; Curtis, Lesley H; Temple, Robert; Andersson, Tomas; Ezekowitz, Justin; Ford, Ian; James, Stefan; Marsolo, Keith; Mirhaji, Parsa; Rocca, Mitra; Rothman, Russell L; Sethuraman, Barathi; Stockbridge, Norman; Terry, Sharon; Wasserman, Scott M; Peterson, Eric D; Hernandez, Adrian F

    2018-04-30

    Electronic health records (EHRs) can be a major tool in the quest to decrease costs and timelines of clinical trial research, generate better evidence for clinical decision making, and advance health care. Over the past decade, EHRs have increasingly offered opportunities to speed up, streamline, and enhance clinical research. EHRs offer a wide range of possible uses in clinical trials, including assisting with prestudy feasibility assessment, patient recruitment, and data capture in care delivery. To fully appreciate these opportunities, health care stakeholders must come together to face critical challenges in leveraging EHR data, including data quality/completeness, information security, stakeholder engagement, and increasing the scale of research infrastructure and related governance. Leaders from academia, government, industry, and professional societies representing patient, provider, researcher, industry, and regulator perspectives convened the Leveraging EHR for Clinical Research Now! Think Tank in Washington, DC (February 18-19, 2016), to identify barriers to using EHRs in clinical research and to generate potential solutions. Think tank members identified a broad range of issues surrounding the use of EHRs in research and proposed a variety of solutions. Recognizing the challenges, the participants identified the urgent need to look more deeply at previous efforts to use these data, share lessons learned, and develop a multidisciplinary agenda for best practices for using EHRs in clinical research. We report the proceedings from this think tank meeting in the following paper. Copyright © 2018 Elsevier, Inc. All rights reserved.

  3. ISS External Payload Platform - a new opportunity for research in the space environment

    NASA Astrophysics Data System (ADS)

    Steimle, Christian; Pape, Uwe

    The International Space Station (ISS) is a widely accepted platform for research activities in low Earth orbit. To a wide extent these activities are conducted in the pressurised laboratories of the station and less in the outside environment. Suitable locations outside the ISS are rare, existing facilities fully booked for the coming years. To overcome this limitation, an external payload platform accessible for small size payloads on a commercial basis will be launched to the ISS and installed on the Japanese Experiment Module External Facility (JEM-EF) in the third quarter of 2014 and will be ready to be used by the scientific community on a fully commercial basis. The new External Payload Platform (EPP) and its opportunities and constraints assessed regarding future research activities on-board the ISS. The small size platform is realised in a cooperation between the companies NanoRacks, Astrium North America in the United States, and Airbus Defence and Space in Germany. The hardware allows the fully robotic installation and operation of payloads. In the nominal mission scenario payload items are installed not later than one year after the signature of the contract, stay in operation for 15 weeks, and can be returned to the scientist thereafter. Payload items are transported among the pressurised cargo usually delivered to the station with various supply vehicles. Due to the high frequency of flights and the flexibility of the vehicle manifests the risk of a delay in the payload readiness can be mitigated by delaying to the next flight opportunity which on average is available not more than two months later. The mission is extra-ordinarily fast and of low cost in comparison to traditional research conducted on-board the ISS and can fit into short-term funding cycles available on national and multi-national levels. The size of the payload items is limited by handling constraints on-board the ISS. Therefore, the standard experiment payload size is a multiple of a

  4. A Model for Data Citation in Astronomical Research Using Digital Object Identifiers (DOIs)

    NASA Astrophysics Data System (ADS)

    Novacescu, Jenny; Peek, Joshua E. G.; Weissman, Sarah; Fleming, Scott W.; Levay, Karen; Fraser, Elizabeth

    2018-05-01

    Standardizing and incentivizing the use of digital object identifiers (DOIs) to aggregate and identify both data analyzed and data generated by a research project will advance the field of astronomy to match best practices in other research fields like geoscience and medicine. An increase in the use of DOIs will prepare the discipline for changing expectations among funding agencies and publishers, who increasingly expect accurate and thorough data citation to accompany scientific outputs. The use of DOIs ensures a robust, sustainable, and interoperable approach to data citation in which due credit is given to the researchers and institutions who produce and maintain the primary data. We describe in this work the advantages of DOIs for data citation and best practices for integrating a DOI service in an astronomical archive. We report on a pilot project carried out in collaboration with AAS journals. During the course of the 1.5-year long pilot, over 75% of submitting authors opted to use the integrated DOI service to clearly identify data analyzed during their research project when prompted at the time of paper submission.

  5. Future opportunities in nanophotonics

    NASA Astrophysics Data System (ADS)

    Prasad, Paras N.

    2003-11-01

    Nanophotonics, dealing with optical science and technology at nanoscale, is an exciting new frontier, which provides numerous opportunities both for fundamental research and new applications of photonics. The Institute for Lasers, Photonics and Biophotonics at Buffalo has a comprehensive multidisciplinary program in Nanophotonics funded by the United States Department of Defense. This program focuses on three major areas of Nanophotonics: (i) interactions involving nanoscale confined radiation, (ii) use of nanoscale photoexcitation for nanofabrication and (iii) design and control of excitation dynamics in nanostructured optical materials. Selected examples of our accomplishments in nanophotonics are presented here which illustrate some of the opportunities.

  6. The 1000 Genomes Project: new opportunities for research and social challenges

    PubMed Central

    2010-01-01

    The 1000 Genomes Project, an international collaboration, is sequencing the whole genome of approximately 2,000 individuals from different worldwide populations. The central goal of this project is to describe most of the genetic variation that occurs at a population frequency greater than 1%. The results of this project will allow scientists to identify genetic variation at an unprecedented degree of resolution and will also help improve the imputation methods for determining unobserved genetic variants that are not represented on current genotyping arrays. By identifying novel or rare functional genetic variants, researchers will be able to pinpoint disease-causing genes in genomic regions initially identified by association studies. This level of detailed sequence information will also improve our knowledge of the evolutionary processes and the genomic patterns that have shaped the human species as we know it today. The new data will also lay the foundation for future clinical applications, such as prediction of disease susceptibility and drug response. However, the forthcoming availability of whole genome sequences at affordable prices will raise ethical concerns and pose potential threats to individual privacy. Nevertheless, we believe that these potential risks are outweighed by the benefits in terms of diagnosis and research, so long as rigorous safeguards are kept in place through legislation that prevents discrimination on the basis of the results of genetic testing. PMID:20193048

  7. Systematically Identifying Relevant Research: Case Study on Child Protection Social Workers' Resilience

    ERIC Educational Resources Information Center

    McFadden, Paula; Taylor, Brian J.; Campbell, Anne; McQuilkin, Janice

    2012-01-01

    Context: The development of a consolidated knowledge base for social work requires rigorous approaches to identifying relevant research. Method: The quality of 10 databases and a web search engine were appraised by systematically searching for research articles on resilience and burnout in child protection social workers. Results: Applied Social…

  8. International Opportunities and Programs at NSF

    NASA Astrophysics Data System (ADS)

    Wodarczyk, F.

    2006-05-01

    The National Science Foundation's Office of International Science and Engineering (OISE) promotes the development of an integrated, Foundation-wide international strategy for international science and engineering activities both inside and outside NSF and manages international programs that are innovative, catalytic, and responsive to a broad range of NSF interests. Specifically, OISE supports programs to expand and enhance leading-edge international research and education opportunities for U.S. scientists and engineers, especially at the early career stage. It works to build and strengthen effective institutional partnerships throughout the global science and engineering research and education community, and it supports international collaborations in NSF's priority research areas. This talk will highlight opportunities for international collaboration for individuals at all levels of their careers, from student to established researcher, with examples of supported programs. Some recent activities focus on bringing together researchers in scientific disciplines and experts in cyberinfrastructure to promote and enable international data collection, manipulation, storage, and sharing via high-speed networks.

  9. Human Research Program Opportunities

    NASA Technical Reports Server (NTRS)

    Kundrot, Craig E.

    2014-01-01

    The goal of HRP is to provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration. The Human Research Program was designed to meet the needs of human space exploration, and understand and reduce the risk to crew health and performance in exploration missions.

  10. Research Opportunities in Nutrition and Metabolism in Space

    NASA Technical Reports Server (NTRS)

    Altman, Philip L. (Editor); Fisher, Kenneth D. (Editor)

    1986-01-01

    The objectives of the Life Sciences Research Office (LSRO) study on nutrient requirements for meeting metabolic needs in manned space flights are as follows: review extant knowledge on the subject; identify significant gaps in knowledge; formulate suggestions for possible research; and produce a documented report of the foregoing items that can be used for program planning. In accordance with NASA's request for this study, the report focuses on issues of nutrition and metabolism that relate primarily to the contemplated United States Space Station, secondarily to the Shuttle Program as an orbital test bed for operational studies, and incidentally to scenarios for future long-term space flights. Members of the LSRO ad hoc Working Group on Nutrition and Metabolism were provided with pertinent articles and summaries on the subject. At the meeting of the Working Group, presentations were made by NASA Headquarters program staff on past experiences relative to space-flight nutrition and metabolism, as well as scenarios for future flights. The discussions of the ad hoc Working Group focused on the following: (1) metabolic needs related to work and exercise; (2) nutrients required to meet such needs; (3) food types, management, and records; and (4) nutritional amelioration or prevention of space-related physiological and behavioral changes.

  11. Geoscience Education Research: A Brief History, Context and Opportunities

    NASA Astrophysics Data System (ADS)

    Mogk, D. W.; Manduca, C. A.; Kastens, K. A.

    2011-12-01

    DBER combines knowledge of teaching and learning with deep knowledge of discipline-specific science content. It describes the discipline-specific difficulties learners face and the specialized intellectual and instructional resources that can facilitate student understanding (NRC, 2011). In the geosciences, content knowledge derives from all the "spheres, the complex interactions of components of the Earth system, applications of first principles from allied sciences, an understanding of "deep time", and approaches that emphasize the interpretive and historical nature of geoscience. Insights gained from the theory and practice of the cognitive and learning sciences that demonstrate how people learn, as well as research on learning from other STEM disciplines, have helped inform the development of geoscience curricular initiatives. The Earth Science Curriculum Project (1963) was strongly influenced by Piaget and emphasized hands-on, experiential learning. Recognizing that education research was thriving in related STEM disciplines a NSF report (NSF 97-171) recommended "... that GEO and EHR both support research in geoscience education, helping geoscientists to work with colleagues in fields such as educational and cognitive psychology, in order to facilitate development of a new generation of geoscience educators." An NSF sponsored workshop, Bringing Research on Learning to the Geosciences (2002) brought together geoscience educators and cognitive scientists to explore areas of mutual interest, and identified a research agenda that included study of spatial learning, temporal learning, learning about complex systems, use of visualizations in geoscience learning, characterization of expert learning, and learning environments. Subsequent events have focused on building new communities of scholars, such as the On the Cutting Edge faculty professional development workshops, extensive collections of online resources, and networks of scholars that have addressed teaching

  12. Epigenetic Research in Cancer Epidemiology: Trends, Opportunities, and Challenges

    PubMed Central

    Verma, Mukesh; Rogers, Scott; Divi, Rao L.; Schully, Sheri D.; Nelson, Stefanie; Su, L. Joseph; Ross, Sharon; Pilch, Susan; Winn, Deborah M.; Khoury, Muin J.

    2014-01-01

    Epigenetics is emerging as an important field in cancer epidemiology that promises to provide insights into gene regulation and facilitate cancer control throughout the cancer care continuum. Increasingly, investigators are incorporating epigenetic analysis into the studies of etiology and outcomes. To understand current progress and trends in the inclusion of epigenetics in cancer epidemiology, we evaluated the published literature and the National Cancer Institute (NCI) supported research grant awards in this field to identify trends in epigenetics research. We present a summary of the epidemiological studies in NCI’s grant portfolio (from January 2005 through December 2012) and in the scientific literature published during the same period, irrespective of support from NCI. Blood cells and tumor tissue were the most commonly used biospecimens in these studies, although buccal cells, cervical cells, sputum, and stool samples also were used. DNA methylation profiling was the focus of the majority of studies, but several studies also measured microRNA profiles. We illustrate here the current status of epidemiologic studies that are evaluating epigenetic changes in large populations. The incorporation of epigenomic assessments in cancer epidemiology studies has and is likely to continue to provide important insights into the field of cancer research. PMID:24326628

  13. Waste audit study: Research and educational institutions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1988-08-15

    This document reports on hazardous-waste reduction audits performed at three diverse research/educational institutions in southern California. Waste-reduction opportunities identified include: utilizing microscale experiments; chemical substitution; treating waste chemicals in the final step in experiments; and recycle, recovery, and treatment options. A generic self-audit was developed for use by educational and research institutions throughout the state.

  14. Idaho Transportation Department : 2010 research program peer exchange.

    DOT National Transportation Integrated Search

    2010-05-01

    The objectives of the peer exchange were to: : 1. Identify strengths, challenges, and opportunities for program and project management; : 2. Understand management expectations of the ITD Research Program; : 3. Review processes for project selection a...

  15. Places of Inequality, Places of Possibility: Mapping "Opportunity in Geography" across Urban School-Communities

    ERIC Educational Resources Information Center

    Green, Terrance L.

    2015-01-01

    For decades, research on geography of opportunity has indicated that where people live impacts their access to opportunities, especially education. Most research on geography of opportunity has focused on spatial inequality between low and high opportunity neighborhoods, which has unintentionally fostered narrow perspectives about low-opportunity…

  16. Youth Opportunity Fund and Youth Capital Fund: Evaluation Findings from Initial Case-Study Visits. Research Report DCSF-RR004

    ERIC Educational Resources Information Center

    O'Donnell, Lisa; Bielby, Gill; Golden, Sarah; Morris, Marian; Walker, Matthew; Maguire, Sue

    2007-01-01

    The Department for Education and Skills (Replace by the Department for Children, Schools and Families as of June 28, 2007) commissioned the National Foundation for Educational Research (NFER) to conduct an evaluation of the Youth Opportunity Fund and Youth Capital Fund (YOF/YCF). This summary presents the main findings from the interim report of…

  17. Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research.

    PubMed

    Larsen, Pernille Stemann; Kamper-Jørgensen, Mads; Adamson, Ashley; Barros, Henrique; Bonde, Jens Peter; Brescianini, Sonia; Brophy, Sinead; Casas, Maribel; Charles, Marie-Aline; Devereux, Graham; Eggesbø, Merete; Fantini, Maria Pia; Frey, Urs; Gehring, Ulrike; Grazuleviciene, Regina; Henriksen, Tine Brink; Hertz-Picciotto, Irva; Heude, Barbara; Hryhorczuk, Daniel O; Inskip, Hazel; Jaddoe, Vincent W V; Lawlor, Debbie A; Ludvigsson, Johnny; Kelleher, Cecily; Kiess, Wieland; Koletzko, Berthold; Kuehni, Claudia Elisabeth; Kull, Inger; Kyhl, Henriette Boye; Magnus, Per; Momas, Isabelle; Murray, Dierdre; Pekkanen, Juha; Polanska, Kinga; Porta, Daniela; Poulsen, Gry; Richiardi, Lorenzo; Roeleveld, Nel; Skovgaard, Anne Mette; Sram, Radim J; Strandberg-Larsen, Katrine; Thijs, Carel; Van Eijsden, Manon; Wright, John; Vrijheid, Martine; Andersen, Anne-Marie Nybo

    2013-07-01

    During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early-life exposures with child development and health. However, to fully exploit the large amount of available resources and to facilitate cross-cohort collaboration, it is necessary to have accessible information on each cohort and its individual characteristics. The aim of this work was to provide an overview of European pregnancy and birth cohorts registered in a freely accessible database located at http://www.birthcohorts.net. European pregnancy and birth cohorts initiated in 1980 or later with at least 300 mother-child pairs enrolled during pregnancy or at birth, and with postnatal data, were eligible for inclusion. Eligible cohorts were invited to provide information on the data and biological samples collected, as well as the timing of data collection. In total, 70 cohorts were identified. Of these, 56 fulfilled the inclusion criteria encompassing a total of more than 500,000 live-born European children. The cohorts represented 19 countries with the majority of cohorts located in Northern and Western Europe. Some cohorts were general with multiple aims, whilst others focused on specific health or exposure-related research questions. This work demonstrates a great potential for cross-cohort collaboration addressing important aspects of child health. The web site, http://www.birthcohorts.net, proved to be a useful tool for accessing information on European pregnancy and birth cohorts and their characteristics. © 2013 John Wiley & Sons Ltd.

  18. Translating research findings of chronic kidney disease management to clinical practice: Challenges and opportunities.

    PubMed

    Stevens, Lesley Ann; Levin, Adeera

    2004-01-01

    Chronic Kidney disease (CKD) has been identified as a public health epidemic, fueled in part by improved outcomes of both diabetic and cardiac patient populations, as well as by the increasing recognition that it is possible to identify CKD at earlier stages. The estimated 8 to 10 million Americans that have CKD, with its concomitant morbidity and mortality, have the potential to overwhelm the current system of specialty practice medicine and health care resources. How can clinicians, clinician scientists, and health care administrators translate research findings into clinical practice in an effective manner to improve the care of this burgeoning patient group? The challenge of translating research into clinical care requires identification of that which we do and do not know, communication of knowledge between those who do and do not know, and efficient collection of information for systematic evaluation. This article will describe the challenges of translating current research findings into clinical practice. There is a need to identify the complexity of CKD disease processes and issues associated with delivery of care and to describe the difficulties in the dissemination of new knowledge to physicians. Because of the propensity of CKD to affect identifiable groups of patients, we will discuss the potential challenges of these strategies given the racial, ethnic, and cultural diversity in North America. A potential solution to these challenges is a new paradigm of "process-based medicine" that integrates clinical and basic science research findings with multidisciplinary and shared care models of health care delivery. In this context, attention to advances in information technology, the cognitive processes that underlie physician learning, and the findings of outcome research may ensure true integration of clinical research and clinical practice.

  19. NCI Think Tank Concerning the Identifiability of Biospecimens and “-Omic” Data

    PubMed Central

    Weil, Carol J.; Mechanic, Leah E.; Green, Tiffany; Kinsinger, Christopher; Lockhart, Nicole C.; Nelson, Stefanie A.; Rodriguez, Laura L.; Buccini, Laura D.

    2014-01-01

    On June 11 and 12, 2012, the National Cancer Institute (NCI) hosted a think tank concerning the identifiability of biospecimens and “omic” Data in order to explore challenges surrounding this complex and multifaceted topic. The think tank brought together forty-six leaders from several fields, including cancer genomics, bioinformatics, human subject protection, patient advocacy, and commercial genetics. The first day involved presentations regarding the state of the science of re-identification; current and proposed regulatory frameworks for assessing identifiability; developments in law, industry and biotechnology; and the expectations of patients and research participants. The second day was spent by think tank participants in small break-out groups designed to address specific sub-topics under the umbrella issue of identifiability, including considerations for the development of best practices for data sharing and consent, and targeted opportunities for further empirical research. We describe the outcomes of this two day meeting, including two complimentary themes that emerged from moderated discussions following the presentations on Day 1, and ideas presented for further empirical research to discern the preferences and concerns of research participants about data sharing and individual identifiability. PMID:23579437

  20. A Framework for Valuing Investments in a Nurturing Society: Opportunities for Prevention Research

    PubMed Central

    Crowley, Max; Jones, Damon

    2017-01-01

    Investing in strategies that aim to build a more nurturing society offers tremendous opportunities for the field of prevention science. Yet, scientists struggle to consistently take their research beyond effectiveness evaluations and actually value the impact of preventive strategies. Ultimately, it is clear that convincing policymakers to make meaningful investments in children and youth will require estimates of the fiscal impact of such strategies across public service systems. The framework offered here values such investments. First, we review current public spending on children and families. Then, we describe how to quantify and monetize the impact of preventive interventions. This includes a new measurement strategy for assessing multi-system service utilization and a price list for key service provision from public education, social services, criminal justice, healthcare, and tax systems. PMID:28247294