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Sample records for idm symphony system

  1. The Integrated Decision Modeling System (IDMS) User’s Manual

    DTIC Science & Technology

    1991-05-01

    AL-TP-1 991-0009 AD-A23 6 033 THE INTEGRATED DECISION MODELING SYSTEM (IDMS) USER’S MANUAL IJonathan C. Fast John N. Taylor Metrica , Incorporated...Looper 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) . PERFORMING ORGANIZATION REPORT NUMBER Metrica , Incorporated 8301 Broadway, Suite 215 San

  2. Symphony: SirsiDynix's Flagship Integrated Library System--A Horizon User's Perspective

    ERIC Educational Resources Information Center

    Khurshid, Zahiruddin; Al-Baridi, Saleh

    2009-01-01

    At the end of 2007, SirsiDynix introduced the first version of Symphony, its new flagship Integrated Library System (ILS). This article begins with a look at the evolution of Symphony, user reactions to Symphony, and Symphony's design and functionality. The authors, along with a team of librarians from various functional areas, have completed…

  3. Solar System Symphony: Combining astronomy with live classical music

    NASA Astrophysics Data System (ADS)

    Kremer, Kyle; WorldWide Telescope

    2017-01-01

    Solar System Symphony is an educational outreach show which combines astronomy visualizations and live classical music. As musicians perform excerpts from Holst’s “The Planets” and other orchestral works, visualizations developed using WorldWide Telescope and NASA images and animations are projected on-stage. Between each movement of music, a narrator guides the audience through scientific highlights of the solar system. The content of Solar System Symphony is geared toward a general audience, particularly targeting K-12 students. The hour-long show not only presents a new medium for exposing a broad audience to astronomy, but also provides universities an effective tool for facilitating interdisciplinary collaboration between two divergent fields. The show was premiered at Northwestern University in May 2016 in partnership with Northwestern’s Bienen School of Music and was recently performed at the Colburn Conservatory of Music in November 2016.

  4. Integrated DWPF Melter System (IDMS) campaign report: The first two noble metals operations

    SciTech Connect

    Hutson, N.D.; Zamecnik, J.R.; Smith, M.E.; Miller, D.H.; Ritter, J.A.

    1991-06-06

    The Integrated DWPF Melter System (IDMS) is designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas systems. The facility is the first pilot-scale melter system capable of processing mercury, and flowsheet levels of halides and noble metals. In order to characterize the processing of noble metals (Pd, Rh, Ru, and Ag) on a large scale, the IDMS will be operated batchstyle for at least nine feed preparation cycles. The first two of these operations are complete. The major observation to date occurred during the second run when significant amounts of hydrogen were evolved during the feed preparation cycle. The runs were conducted between June 7, 1990 and March 8, 1991. This time period included nearly six months of ``fix-up`` time when forced air purges were installed on the SRAT MFT and other feed preparation vessels to allow continued noble metals experimentation.

  5. Integrated DWPF Melter System (IDMS) campaign report: Hanford Waste Vitrification Plan (HWVP) process demonstration

    SciTech Connect

    Hutson, N.D.

    1992-08-10

    Vitrification facilities are being developed worldwide to convert high-level nuclear waste to a durable glass form for permanent disposal. Facilities in the United States include the Department of Energy`s Defense Waste Processing Facility (DWPF) at the Savannah River Site, the Hanford Waste Vitrification Plant (HWVP) at the Hanford Site and the West Valley Demonstration Project (WVDP) at West Valley, NY. At each of these sites, highly radioactive defense waste will be vitrified to a stable borosilicate glass. The DWPF and WVDP are near physical completion while the HWVP is in the design phase. The Integrated DWPF Melter System (IDMS) is a vitrification test facility at the Savannah River Technology Center (SRTC). It was designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas treatment systems. Because of the similarities of the DWPF and HWVP processes, the IDMS facility has also been used to characterize the processing behavior of a reference NCAW simulant. The demonstration was undertaken specifically to determine material balances, to characterize the evolution of offgas products (especially hydrogen), to determine the effects of noble metals, and to obtain general HWVP design data. The campaign was conducted from November, 1991 to February, 1992.

  6. Durability of glasses from the Hg-doped Integrated DWPF Melter System (IDMS) campaign

    SciTech Connect

    Jantzen, C.M.

    1992-08-30

    The Integrated DWPF Melter System (IDMS) for the vitrification of high-level radioactive wastes is designed and constructed to be a 1/9th scale prototype of the full scale Defense Waste Processing Facility (DWPF) melter. The IDMS facility is the first engineering scale melter system capable of processing mercury, and flowsheet levels of halides and noble metals. In order to determine the effects of mercury on the feed preparation process, the off-gas chemistry, glass melting behavior, and glass durability, a three-run mercury (Hg) campaign was conducted. The glasses produced during the Hg campaign were composed of Batch 1 sludge, simulated precipitate hydrolysis aqueous product (PHA) from the Precipitate Hydrolysis Experimental Facility (PHEF), and Frit 202. The glasses were produced using the DWPF process/product models for glass durability, viscosity, and liquidus. The durability model indicated that the glasses would all be more durable than the glass qualified in the DWPF Environmental Assessment (EA). The glass quality was verified by performing the Product Consistency Test (PCT) which was designed for glass durability testing in the DWPF.

  7. Design and evaluation of an IDM-based MIMO FSO system over Gamma-Gamma turbulence channels

    NASA Astrophysics Data System (ADS)

    Zhang, Chenglei; Zhou, Xiaolin; Zheng, Xiaowei; Du, Jianhong

    2011-12-01

    In this paper, we design an interleave-division-multiplexing (IDM) based multiple-input multiple-output (MIMO) free-space optics (FSO) communication system. The system overcomes problems harassing conventional optical MIMO systems such as restrictions of antenna number and high complexity in receiver. An iterative on-off keying (OOK) modulated IDM MIMO detection algorithm is developed. Expression of an upper bound of frame-error-rate (FER) is derived. In addition, we evaluate the BER performance of the proposed optical MIMO scheme in various FSO scenarios. Simulations confirm that the proposed scheme can effectively increase the feasibility of FSO communications over Gamma-Gamma turbulence-induced fading channels.

  8. Seismic Symphonies

    NASA Astrophysics Data System (ADS)

    Strinna, Elisa; Ferrari, Graziano

    2015-04-01

    The project started in 2008 as a sound installation, a collaboration between an artist, a barrel organ builder and a seismologist. The work differs from other attempts of sound transposition of seismic records. In this case seismic frequencies are not converted automatically into the "sound of the earthquake." However, it has been studied a musical translation system that, based on the organ tonal scale, generates a totally unexpected sequence of sounds which is intended to evoke the emotions aroused by the earthquake. The symphonies proposed in the project have somewhat peculiar origins: they in fact come to life from the translation of graphic tracks into a sound track. The graphic tracks in question are made up by copies of seismograms recorded during some earthquakes that have taken place around the world. Seismograms are translated into music by a sculpture-instrument, half a seismograph and half a barrel organ. The organ plays through holes practiced on paper. Adapting the documents to the instrument score, holes have been drilled on the waves' peaks. The organ covers about three tonal scales, starting from heavy and deep sounds it reaches up to high and jarring notes. The translation of the seismic records is based on a criterion that does match the highest sounds to larger amplitudes with lower ones to minors. Translating the seismogram in the organ score, the larger the amplitude of recorded waves, the more the seismogram covers the full tonal scale played by the barrel organ and the notes arouse an intense emotional response in the listener. Elisa Strinna's Seismic Symphonies installation becomes an unprecedented tool for emotional involvement, through which can be revived the memory of the greatest disasters of over a century of seismic history of the Earth. A bridge between art and science. Seismic Symphonies is also a symbolic inversion: the instrument of the organ is most commonly used in churches, and its sounds are derived from the heavens and

  9. Evaluation of the MIM Symphony treatment planning system for low-dose-rate- prostate brachytherapy.

    PubMed

    Dhanesar, Sandeep K; Lim, Tze Y; Du, Weiliang; Bruno, Teresa L; Frank, Steven J; Kudchadker, Rajat J

    2015-09-08

    MIM Symphony is a recently introduced low-dose-rate prostate brachytherapy treatment planning system (TPS). We evaluated the dosimetric and planning accuracy of this new TPS compared to the universally used VariSeed TPS. For dosimetric evaluation of the MIM Symphony version 5.4 TPS, we compared dose calculations from the MIM Symphony TPS with the formalism recommended by the American Association of Physicists in Medicine Task Group 43 report (TG-43) and those generated by the VariSeed version 8.0 TPS for iodine-125 (I-125; Models 6711 and IAI-125A), palladium-103 (Pd-103; Model 200), and cesium-131 (Cs-131; Model Cs-1). Validation was performed for both line source and point source approximations. As part of the treatment planning validation, first a QA phantom (CIRS Brachytherapy QA Phantom Model 045 SN#D7210-3) containing three ellipsoid objects with certified volumes was scanned in order to check the volume accuracy of the contoured structures in MIM Symphony. Then the DICOM data containing 100 patient plans from the VariSeed TPS were imported into the MIM Symphony TPS. The 100 plans included 25 each of I-125 pre-implant plans, Pd-103 pre-implant plans, I-125 Day 30 plans (i.e., from 1 month after implantation), and Pd-103 Day 30 plans. The dosimetric parameters (including prostate volume, prostate D90 values, and rectum V100 values) of the 100 plans were calculated independently on the two TPSs. Other TPS tests that were done included verification of source input and geometrical accuracy, data transfer between different planning systems, text printout, 2D dose plots, DVH printout, and template grid accuracy. According to the line source formalism, the dosimetric results between the MIM Symphony TPS and TG-43 were within 0.5% (0.02 Gy) for r > 1 cm. In the line source approximation validation, MIM Symphony TPS values agreed with VariSeed TPS values to within 0.5% (0.09 Gy) for r > 1 cm. Similarly, in point source approximation validation, the MIM Symphony values

  10. A Contextual Model for Identity Management (IdM) Interfaces

    ERIC Educational Resources Information Center

    Fuller, Nathaniel J.

    2014-01-01

    The usability of Identity Management (IdM) systems is highly dependent upon design that simplifies the processes of identification, authentication, and authorization. Recent findings reveal two critical problems that degrade IdM usability: (1) unfeasible techniques for managing various digital identifiers, and (2) ambiguous security interfaces.…

  11. A Symphony of Sites

    ERIC Educational Resources Information Center

    Roland, Craig

    2007-01-01

    Symphony, as Daniel Pink defines it in his book "A Whole New Mind," is "the ability to put together the pieces" in a unified whole. It is the capacity to "see the big picture," to notice relationships between seemingly unrelated fields or things, to think metaphorically, and to invent something new by combining elements that nobody else thought to…

  12. NY TBO Research: Integrated Demand Management (IDM): IDM Concept, Tools, and Training Package

    NASA Technical Reports Server (NTRS)

    Smith, Nancy

    2016-01-01

    A series of human-in-the-loop simulation sessions were conducted in the Airspace Operations Laboratory (AOL) to evaluate a new traffic management concept called Integrated Demand Management (IDM). The simulation explored how to address chronic equity, throughput and delay issues associated with New Yorks high-volume airports by operationally integrating three current and NextGen capabilities the Collaborative Trajectory Options Program (CTOP), Time-Based Flow Management (TBFM) and Required Time of Arrival (RTA) in order to better manage traffic demand within the National Air Traffic System. A package of presentation slides was developed to describe the concept, tools, and training materials used in the simulation sessions. The package will be used to outbrief our stakeholders by both presenting orally and disseminating of the materials via email.

  13. Investigation of a method for repairing the hot gas system branch 2 of the Symphonie-Satellite MV2 in orbit

    NASA Technical Reports Server (NTRS)

    Braun, H.

    1981-01-01

    The failure of all engines on the Symphonie MV2 satellite is attributed to blockage of the oxidizer branch caused by metal salts precipitating and forming a gel which constricts the narrow passage. Laboratory tests and other simulations conducted to observe the behavior of artificially produced jellies on a vacuum show that a removal or at least a reduction of the blockage in the oxidizer branch is possible by evacuation. The greatest blockage appears to occur in the filter. This fact restricts the capability to perform repairs in orbit because the filter installed ahead of the valve cannot by subjected to a vacuum.

  14. The CRRES IDM spacecraft experiment for insulator discharge pulses

    NASA Astrophysics Data System (ADS)

    Frederickson, A. R.; Mullen, E. G.; Kerns, K. J.; Robinson, P. A.; Holeman, E. G.

    1993-04-01

    The Internal Discharge Monitor (IDM) is designed to observe electrical pulses from common electrical insulators in space service. The characteristics of the instrument are described. The IDM was flown on the Combined Release and Radiation Effects Satellite (CRRES). The sixteen insulator samples included G10 circuit boards, FR4 and PTFE fiberglass circuit boards, FEP Teflon, alumina, and wires with common insulations. The samples are fully enclosed, mutually isolated, and space radiation penetrates 0.02 cm of aluminum before striking the samples. Published data in the literature provides a simple method for determining the flux of penetrating electrons. The pulse rate is compared to the penetrating flux of electrons.

  15. uniVERSE: A Thought Symphony

    NASA Astrophysics Data System (ADS)

    Schwartz, G.

    2011-06-01

    Universe: A Thought Symphony, recasting the last, most ambitious, yet uncomplicated composition, Universe Symphony of American composer Charles Ives, we will match it with a new libretto derived from selections of Teilhard de Chardin's Hymn of the Universe and George V. Coyne, S.J. and Alessandro Omizzolo's Wayfarers In the Cosmos. The piece (running time 37 minutes), has three movements: Past-moving from Chaos, the formation of the waters and mountains; Present-the formation of the Earth and the firmament, evolution in nature and humanity; and Future-the rise of all beyond.

  16. Entitlement Management: Ready to Enter the IdM Mainstream

    NASA Astrophysics Data System (ADS)

    Gebel, Gerry; Wang, Alice

    Externalizing authorization processing from business applications has been a goal for architects and developers for many years. Recent compliance demands for more granular access control and policy transparency have increased the urgency to adopt an architectural model where authorization and entitlement management are consumed as a service rather than embedded within business applications. Major software vendors, such as Microsoft, Oracle, and SAP, are making significant steps to separate IdM functionality, including entitlement management from application logic. The market has also responded with a plethora of products that provide entitlement management and authorization functionality for commercial or custom-built application environments. Finally, the Extensible Access Control Markup Language (XACML) has emerged as the consensus authorization standard being supported by a growing number of IT and application vendors. Collectively, these forces form the basis of a nascent IdM market segment referred to as entitlement management.

  17. "La Symphonie pastorale" pour des etudiants moyennement avances ("La Symphonie pastorale" for Moderately Advanced Students).

    ERIC Educational Resources Information Center

    St. Ours, Kathryn

    2002-01-01

    Recommends the study of "La Symphonie pastorale," a novel by Andre Gide, for moderately advanced students of French as a second language. Presents various activities to be performed before, during and after reading the story, a pastor's journal, to help students understand the ironic aspects and ambiguities of the book. (AS)

  18. Impact of Isotope Dilution Mass Spectrometry (IDMS) Standardization on Carboplatin Dose and Adverse Events

    PubMed Central

    Lawson, Justin; Switchenko, Jeffrey M.; McKibbin, Trevor; Harvey, R. Donald

    2017-01-01

    BACKGROUND When using area under the concentration-time curve-based strategies for dosing carboplatin, accurate estimation of glomerular filtration rate is required for determining dose. Commonly, the Cockcroft–Gault equation is used, which is dependent on measurement of serum creatinine (SCr). Because analysis of SCr changed to an isotope dilution mass spectrometry (IDMS) standard, we sought to determine the impact of this assay change on carboplatin dosing and related toxicity. METHODS This was a single-center, retrospective chart review of adults treated with carboplatin between April 2008 and April 2010 divided into cohorts that initiated carboplatin before or after IDMS standardization. End points included grade 3 thrombocytopenia, decrease in platelet count, and hospitalization and were evaluated in cohorts based on concomitant chemotherapy. RESULTS The chart review identified 158 patients, with 63 patients in the pre-IDMS group and 95 patients in the post-IDMS group. Average SCr (pre 1.01 mg/dl vs post 0.86 mg/dl, p<0.001) and average carboplatin dose (pre 580 mg vs post 703 mg, p<0.001) were significantly different between the groups. The frequency of grade 3 thrombocytopenia was not statistically significant across three partner chemotherapy cohorts before and after IDMS implementation. CONCLUSION IDMS standardization led to an overall decrease in SCr with subsequent increase in carboplatin doses. However, no increase in recorded adverse events was observed, suggesting that the clinical relevance in toxicity from higher doses was minimal. PMID:27130286

  19. Symphony of colours in the Tarantula

    NASA Astrophysics Data System (ADS)

    2004-12-01

    hi-res Size hi-res: 1058 Kb Credits: ESA/NASA, ESO and Danny LaCrue Symphony of colours in the Tarantula The Tarantula is situated 170 000 light-years away in the Large Magellanic Cloud (LMC) in the southern sky and is clearly visible to the naked eye as a large milky patch. Astronomers believe that this smallish irregular galaxy is currently going through a violent period in its life. It is orbiting around the Milky Way and has had several close encounters with it. It is believed that the interaction with the Milky Way has caused an episode of energetic star formation - part of which is visible as the Tarantula Nebula. Just above the centre of the image there is a huge cluster of very hot stars called R136. The stars in R136 are also among the most massive stars we know. R136 is also a very young cluster, its oldest stars being 'just' 5 million years old or so. Its smallest stars, however, are still forming, so astronomers observe R136 to try to understand the early stages of stellar evolution. Near the lower edge of the image we find the star cluster Hodge 301. Hodge 301 is almost 10 times older than R136. Some of the stars in Hodge 301 are so old that they have already exploded as supernovae. The shockwave from this explosion has compressed the gas in the Tarantula into the filaments and sheets that are seen around the cluster. This mosaic of the Tarantula Nebula consists of images from the NASA/ESA Hubble Space Telescope’s Wide Field and Planetary Camera 2 (WFPC2) and was created by 23 year old amateur astronomer Danny LaCrue. The image was constructed by 15 individual exposures taken through three narrow-band filters allowing light from ionised oxygen (501 nm, shown as blue), hydrogen-alpha (656 nm, shown as green) and ionised sulphur (672 nm, shown as red). The exposure time for the individual WFPC2 images vary between 800 and 2800 seconds in each filter. The Hubble data have been superimposed onto images taken through matching narrow-band filters with the

  20. 78 FR 38584 - Safety Zone; San Diego Symphony Summer POPS Fireworks 2013 Season, San Diego, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego Symphony Summer POPS Fireworks... Symphony Summer POPS Fireworks 2013 season. This safety zone is necessary to provide for the safety of the... San Diego Symphony Summer POPS, which will include a fireworks presentation from a barge in San...

  1. Creatinine Assay Attainment of Analytical Performance Goals Following Implementation of IDMS Standardization

    PubMed Central

    Lee, Elizabeth Sunmin; Collier, Christine P.; White, Christine A.

    2017-01-01

    Background: The international initiative to standardize creatinine (Cr) assays by tracing reference materials to Isotope Dilution Mass Spectrometry (IDMS) assigned values was implemented to reduce interlaboratory variability and improve assay accuracy. Objective: The aims of this study were to examine whether IDMS standardization has improved Cr assay accuracy (bias), interlaboratory variability (precision), total error (TE), and attainment of recommended analytical performance goals. Methods: External Quality Assessment (EQA) data (n = 66 challenge vials) from Ontario, Canada, were analyzed. The bias, precision, TE, and the number of EQA challenge vials meeting performance goals were determined by assay manufacturer before (n = 32) and after (n = 34) IDMS implementation. Results: The challenge vials with the worst bias and precision were spiked with known common interfering substances (glucose and bilirubin). IDMS standardization improved assay bias (10.4%-1.6%, P < .001), but precision remained unchanged (5.0%-4.7%, P = .5) with performance goals not consistently being met. Precision and TE goals based on biologic variation were attained by only 29% to 69% and 32% to 62% of challenge vials. Conclusions: While IDMS standardization has improved Cr assay accuracy and thus reduced TE, significant interlaboratory variability remains. Contemporary Cr assays do not currently meet the standards required to allow for accurate and consistent estimated glomerular filtration rate assessment and chronic kidney disease diagnosis across laboratories. Further improvements in Cr assay performance are needed. PMID:28321322

  2. Clock synchronisation experiment in India using symphonie satellite

    NASA Technical Reports Server (NTRS)

    Somayajulu, Y. V.; Mathur, B. S.; Banerjee, P.; Garg, S. C.; Singh, L.; Sood, P. C.; Tyagi, T. R.; Jain, C. L.; Kumar, K.

    1979-01-01

    A recent clock synchronization experiment between the National Physical Laboratory (NPL), New Delhi and Space Applications Center (SAC), Ahemedabad, in India via geostationary satellite symphonie 2, stationed at 49 E longitude, is reported. A two-way transmission using a microwave transponder considered to provide the greatest precision in synchronization of two remote clocks is described.

  3. Accurate quantification of total chromium and its speciation form Cr(VI) in water by ICP-DRC-IDMS and HPLC/ICP-DRC-IDMS.

    PubMed

    Markiewicz, Barbara; Komorowicz, Izabela; Barałkiewicz, Danuta

    2016-05-15

    Two analytical procedures have been developed for the determination of total chromium (TCr) and its highly toxic species, i.e. Cr(VI) in water samples using the following methods: inductively coupled plasma dynamic reaction cell isotope dilution mass spectrometry (ICP-DRC-IDMS) and high performance liquid chromatography inductively coupled plasma dynamic reaction cell isotope dilution mass spectrometry (HPLC/ICP-DRC-IDMS). Spectral interferences, predominantly occurring in chromium determination, were removed using a dynamic reaction cell (DRC). The presented procedures facilitate the quantification of trace amounts - below 1 µg L(-1) of TCr and individual Cr species - in various water matrices including drinking water and still bottled water with different mineral composition. Special attention has been paid to the adequate preparation of isotopically enriched (53)Cr(VI) standard solution in order to avoid artifacts in chromium speciation. Both procedures were fully validated as well as establishing the traceability and estimation of the uncertainty of measurement were carried out. Application of all of the above mentioned elements and of the isotope dilution technique, which provides the highest quality of metrological traceability, allowed to obtain reliable and high quality results of chromium determination in water samples. Additionally, the comparison of two methods: HPLC/ICP-DRC-MS and HPLC/ICP-DRC-IDMS for Cr(VI) determination, was submitted basing on the validation parameters. As a result, the lower values for these parameters were obtained using the second method.

  4. Einstein's Symphony: A Gravitational Wave Voyage Through Space and Time

    NASA Astrophysics Data System (ADS)

    Shapiro Key, Joey; Yunes, Nico; Grimberg, Irene

    2015-01-01

    Einstein's Symphony: A Gravitational Wave Voyage Through Space and Time is a gravitational wave astronomy planetarium show in production by a collaboration of scientists, filmmakers, and artisits from the Center for Gravitational Wave Astonomy (CGWA) at the University of Texas at Brownsville (UTB) and Montana State University (MSU). The project builds on the success of the interdisciplinary Celebrating Einstein collaboration. The artists and scientists who created the A Shout Across Time original film and the Black (W)hole immersive art installation for Celebrating Einstein are teaming with the Museum of the Rockies Taylor Planetarium staff and students to create a new full dome Digistar planetarium show that will be freely and widely distributed to planetaria in the US and abroad. The show uses images and animations filmed and collected for A Shout Across Time and for Black (W)hole as well as new images and animations and a new soundtrack composed and produced by the MSU School of Music to use the full capability of planetarium sound systems. The planetarium show will be narrated with ideas drawn from the Celebrating Einstein danced lecture on gravitational waves that the collaboration produced. The combination of products, resources, and team members assembled for this project allows us to create an original planetarium show for a fraction of the cost of a typical show. In addition, STEM education materials for G6-12 students and teachers will be provided to complement and support the show. This project is supported by the Texas Space Grant Consortium (TSGC), Montana Space Grant Consortium (MSGC), and the American Physical Society (APS).

  5. 77 FR 40511 - Safety Zone; GR Symphony Fireworks Display, Kalamazoo Lake, Saugatuck, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; GR Symphony Fireworks Display, Kalamazoo... restrict vessels from a portion of Kalamazoo Lake during the GR Symphony Fireworks display. This temporary safety zone is necessary to protect spectators and vessels from the hazards associated with a...

  6. Hormone symphony during root growth and development.

    PubMed

    Garay-Arroyo, Adriana; De La Paz Sánchez, María; García-Ponce, Berenice; Azpeitia, Eugenio; Alvarez-Buylla, Elena R

    2012-12-01

    Hormones regulate plant growth and development in response to external environmental stimuli via complex signal transduction pathways, which in turn form complex networks of interaction. Several classes of hormones have been reported, and their activity depends on their biosynthesis, transport, conjugation, accumulation in the vacuole, and degradation. However, the activity of a given hormone is also dependent on its interaction with other hormones. Indeed, there is a complex crosstalk between hormones that regulates their biosynthesis, transport, and/or signaling functionality, although some hormones have overlapping or opposite functions. The plant root is a particularly useful system in which to study the complex role of plant hormones in the plastic control of plant development. Physiological, cellular, and molecular genetic approaches have been used to study the role of plant hormones in root meristem homeostasis. In this review, we discuss recent findings on the synthesis, signaling, transport of hormones and role during root development and examine the role of hormone crosstalk in maintaining homeostasis in the apical root meristem.

  7. Checkout and start-up of the integrated DWPF (Defense Waste Processing Facility) melter system

    SciTech Connect

    Smith, M.E.; Hutson, N.D.; Miller, D.H.; Morrison, J.; Shah, H.; Shuford, J.A.; Glascock, J.; Wurzinger, F.H.; Zamecnik, J.R.

    1989-11-11

    The Integrated DWPF Melter System (IDMS) is a one-ninth-scale demonstration of the Defense Waste Processing Facility (DWPF) feed preparation, melter, and off-gas systems. The IDMS will be the first engineering-scale melter system at SRL to process mercury and flowsheet levels of halides and sulfates. This report includes a summary of the IDMS program objectives, system and equipment descriptions, and detailed discussions of the system checkout and start-up. 10 refs., 44 figs., 20 tabs.

  8. Validation of creatinine assays utilizing HPLC and IDMS traceable standards in sera of children.

    PubMed

    Schwartz, George J; Kwong, Tai; Erway, Brian; Warady, Bradley; Sokoll, Lori; Hellerstein, Stanley; Dharnidharka, Vikas; Furth, Susan; Muñoz, Alvaro

    2009-01-01

    The purpose of this study was to validate serum creatinine (SCr) concentrations assayed in the Central Biochemistry Laboratory of the National Institutes of Health (NIH)-funded Chronic Kidney Disease in Children (CKiD) study utilizing an enzymatic assay (Siemens Advia 2400) against a method traceable to reference isotope dilution mass spectroscopy (IDMS) developed by the National Institute of Standards and Technology (NIST). High-performance liquid chromatography (HPLC) measured SCr after external validation utilizing IDMS-based standard reference materials. Sera from the first 201 subjects enrolled in CKiD were analyzed and compared for creatinine concentration by enzymatic and HPLC methods. Fifty "normal" pediatric sera were subsequently analyzed. Finally, a "pediatric" reference standard was prepared and examined for accuracy and precision. Enzymatic SCr concentrations (median 1.4 mg/dl) of CKiD subjects were well correlated with HPLC (r = 0.984) but were slightly higher (+7%; p < 0.001). Agreement was poorer at lower SCr (median 0.4 mg/dl) when using samples from normal children and the "pediatric" reference standard. However, the Roche enzymatic assay was comparable with HPLC in accuracy and precision. Referring physicians should be aware of the accuracy and reproducibility of their laboratory's SCr assay. Our enzymatic assay agreed well with HPLC in CKiD subjects with elevated SCr. We suggest that NIST develop a pediatric SCr standard reference material for use by assay manufacturers to improve accuracy and precision of assays at the low SCr levels observed in most pediatric patients.

  9. The Pulsar Quartet: Listening to a Galactic Symphony

    NASA Astrophysics Data System (ADS)

    Kiziltan, Bülent

    2014-06-01

    Pulsars are exotic dead stars that emit very regular radio pulses. These pulses are attributed to their regular rotation. Some pulsars are spinning fast enough that the audio equivalent waveform of their pulses fall within our hearing range. If human ears were tuned to radio waves it would have been possible to ‘hear’ these very compact stars. We produced the audio waveform of these pulsar signals and mapped them onto a frequency chart to find the corresponding musical notes. We use these ‘audible' pulsars like musical instruments in a symphony orchestra to play a full quartet. At the same time, an accompanying visual interface shows the realistic distribution of all pulsars in our own Galaxy. Pulsars shine as they play each note in the quartet with realistic brightening and subsequent dimming proportional to their rotational energies. This can serve as an educational tool at all levels to demonstrate many interesting aspects of stellar evolution and articulate an aesthetic connection of us with the cosmos. Interested in watching the light show while the Milky Way Pulsar Orchestra plays a quartet?

  10. Molar mass of silicon highly enriched in 28Si determined by IDMS

    NASA Astrophysics Data System (ADS)

    Pramann, Axel; Rienitz, Olaf; Schiel, Detlef; Schlote, Jan; Güttler, Bernd; Valkiers, Staf

    2011-04-01

    The molar mass of a new silicon crystal material highly enriched in 28Si ('Si28', x(28Si) >99.99%) has been measured for the first time using a combination of a modified isotope dilution mass spectrometry (IDMS) technique and a high resolution multicollector-ICP-mass spectrometer. This work is related to the redetermination of the Avogadro constant NA with an intended relative measurement uncertainty urel(NA) <= 2 × 10-8. The corresponding experimental investigations of the International Avogadro Coordination (IAC) were performed using this novel 'Si28' material. One prerequisite of the redetermination of NA is the determination of the isotopic composition and thus molar mass of 'Si28' with urel(M('Si28')) <= 1 × 10-8. At PTB, a molar mass M('Si28') = 27.976 970 27(23) g mol-1 has been determined with an associated relative uncertainty urel(M('Si28')) = 8.2 × 10-9, opening the opportunity to reach the target uncertainty of NA.

  11. 77 FR 42647 - Safety Zone: San Diego Symphony POPS Fireworks; San Diego, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone: San Diego Symphony POPS Fireworks; San... Fireworks. This safety zone is necessary to provide for the safety of the participants, crew, spectators... Hall are sponsoring the San Diego POPS Fireworks, which will include a fireworks presentation...

  12. The theory of reference values: an unfinished symphony.

    PubMed

    Siest, Gerard; Henny, Joseph; Gräsbeck, Ralph; Wilding, Peter; Petitclerc, Claude; Queraltó, Josep M; Hyltoft Petersen, Peter

    2013-01-01

    The history of the theory of reference values can be written as an unfinished symphony. The first movement, allegro con fuoco, played from 1960 to 1980: a mix of themes devoted to the study of biological variability (intra-, inter-individual, short- and long-term), preanalytical conditions, standardization of analytical methods, quality control, statistical tools for deriving reference limits, all of them complex variations developed on a central melody: the new concept of reference values that would replace the notion of normality whose definition was unclear. Additional contributions (multivariate reference values, use of reference limits from broad sets of patient data, drug interferences) conclude the movement on the variability of laboratory tests. The second movement, adagio, from 1980 to 2000, slowly develops and implements initial works. International and national recommendations were published by the IFCC-LM (International Federation of Clinical Chemistry and Laboratory Medicine) and scientific societies [French (SFBC), Spanish (SEQC), Scandinavian societies…]. Reference values are now topics of many textbooks and of several congresses, workshops, and round tables that are organized all over the world. Nowadays, reference values are part of current practice in all clinical laboratories, but not without difficulties, particularly for some laboratories to produce their own reference values and the unsuitability of the concept with respect to new technologies such as HPLC, GCMS, and PCR assays. Clinicians through consensus groups and practice guidelines have introduced their own tools, the decision limits, likelihood ratios and Reference Change Value (RCV), creating confusion among laboratorians and clinicians in substituting reference values and decision limits in laboratory reports. The rapid development of personalized medicine will eventually call for the use of individual reference values. The beginning of the second millennium is played allegro ma non

  13. Thickness dependence of the interfacial Dzyaloshinskii-Moriya interaction in inversion symmetry broken systems.

    PubMed

    Cho, Jaehun; Kim, Nam-Hui; Lee, Sukmock; Kim, June-Seo; Lavrijsen, Reinoud; Solignac, Aurelie; Yin, Yuxiang; Han, Dong-Soo; van Hoof, Niels J J; Swagten, Henk J M; Koopmans, Bert; You, Chun-Yeol

    2015-07-08

    In magnetic multilayer systems, a large spin-orbit coupling at the interface between heavy metals and ferromagnets can lead to intriguing phenomena such as the perpendicular magnetic anisotropy, the spin Hall effect, the Rashba effect, and especially the interfacial Dzyaloshinskii-Moriya (IDM) interaction. This interfacial nature of the IDM interaction has been recently revisited because of its scientific and technological potential. Here we demonstrate an experimental technique to straightforwardly observe the IDM interaction, namely Brillouin light scattering. The non-reciprocal spin wave dispersions, systematically measured by Brillouin light scattering, allow not only the determination of the IDM energy densities beyond the regime of perpendicular magnetization but also the revelation of the inverse proportionality with the thickness of the magnetic layer, which is a clear signature of the interfacial nature. Altogether, our experimental and theoretical approaches involving double time Green's function methods open up possibilities for exploring magnetic hybrid structures for engineering the IDM interaction.

  14. Thickness dependence of the interfacial Dzyaloshinskii–Moriya interaction in inversion symmetry broken systems

    PubMed Central

    Cho, Jaehun; Kim, Nam-Hui; Lee, Sukmock; Kim, June-Seo; Lavrijsen, Reinoud; Solignac, Aurelie; Yin, Yuxiang; Han, Dong-Soo; van Hoof, Niels J. J.; Swagten, Henk J. M.; Koopmans, Bert; You, Chun-Yeol

    2015-01-01

    In magnetic multilayer systems, a large spin-orbit coupling at the interface between heavy metals and ferromagnets can lead to intriguing phenomena such as the perpendicular magnetic anisotropy, the spin Hall effect, the Rashba effect, and especially the interfacial Dzyaloshinskii–Moriya (IDM) interaction. This interfacial nature of the IDM interaction has been recently revisited because of its scientific and technological potential. Here we demonstrate an experimental technique to straightforwardly observe the IDM interaction, namely Brillouin light scattering. The non-reciprocal spin wave dispersions, systematically measured by Brillouin light scattering, allow not only the determination of the IDM energy densities beyond the regime of perpendicular magnetization but also the revelation of the inverse proportionality with the thickness of the magnetic layer, which is a clear signature of the interfacial nature. Altogether, our experimental and theoretical approaches involving double time Green's function methods open up possibilities for exploring magnetic hybrid structures for engineering the IDM interaction. PMID:26154986

  15. 77 FR 40515 - Safety Zone; Detroit Symphony Orchestra at Ford House Fireworks, Lake St. Clair, Grosse Pointe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    .... SUMMARY: The Coast Guard is establishing a temporary safety zone on ] Lake St. Clair, Grosse Pointe Shores... Orchestra at Ford House Fireworks, Lake St. Clair, Grosse Pointe Shores, MI (a) Location. The safety zone... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Detroit Symphony Orchestra at Ford...

  16. Symphony: a framework for accurate and holistic WSN simulation.

    PubMed

    Riliskis, Laurynas; Osipov, Evgeny

    2015-02-25

    Research on wireless sensor networks has progressed rapidly over the last decade, and these technologies have been widely adopted for both industrial and domestic uses. Several operating systems have been developed, along with a multitude of network protocols for all layers of the communication stack. Industrial Wireless Sensor Network (WSN) systems must satisfy strict criteria and are typically more complex and larger in scale than domestic systems. Together with the non-deterministic behavior of network hardware in real settings, this greatly complicates the debugging and testing of WSN functionality. To facilitate the testing, validation, and debugging of large-scale WSN systems, we have developed a simulation framework that accurately reproduces the processes that occur inside real equipment, including both hardware- and software-induced delays. The core of the framework consists of a virtualized operating system and an emulated hardware platform that is integrated with the general purpose network simulator ns-3. Our framework enables the user to adjust the real code base as would be done in real deployments and also to test the boundary effects of different hardware components on the performance of distributed applications and protocols. Additionally we have developed a clock emulator with several different skew models and a component that handles sensory data feeds. The new framework should substantially shorten WSN application development cycles.

  17. Symphony: A Framework for Accurate and Holistic WSN Simulation

    PubMed Central

    Riliskis, Laurynas; Osipov, Evgeny

    2015-01-01

    Research on wireless sensor networks has progressed rapidly over the last decade, and these technologies have been widely adopted for both industrial and domestic uses. Several operating systems have been developed, along with a multitude of network protocols for all layers of the communication stack. Industrial Wireless Sensor Network (WSN) systems must satisfy strict criteria and are typically more complex and larger in scale than domestic systems. Together with the non-deterministic behavior of network hardware in real settings, this greatly complicates the debugging and testing of WSN functionality. To facilitate the testing, validation, and debugging of large-scale WSN systems, we have developed a simulation framework that accurately reproduces the processes that occur inside real equipment, including both hardware- and software-induced delays. The core of the framework consists of a virtualized operating system and an emulated hardware platform that is integrated with the general purpose network simulator ns-3. Our framework enables the user to adjust the real code base as would be done in real deployments and also to test the boundary effects of different hardware components on the performance of distributed applications and protocols. Additionally we have developed a clock emulator with several different skew models and a component that handles sensory data feeds. The new framework should substantially shorten WSN application development cycles. PMID:25723144

  18. The Iterative Decision Method (IDM): Academy of Health Sciences Reports, Small Group Decision-Making and Problem-Solving Bibliography, and Statistical References.

    DTIC Science & Technology

    1983-03-01

    IDM Bibliography ..L 1 Group decision making has long been a practice of military management . Generally group decisions tend to be more accurate...efficient decision-making management tool by the Office of The Surgeon General (see pages 2 and 3), and continues to be a productive means of providing...Behavior and Human Perform ), many other sources were obtained from the literature of education, sociology, educa- tional technology, and the management

  19. Mining CRRES IDM Pulse Data and CRRES Environmental Data to Improve Spacecraft Charging/Discharging Models and Guidelines

    NASA Technical Reports Server (NTRS)

    Brautigam, D. H.; Frederickson, A. R.

    2004-01-01

    One can truly predict the charging and pulsing in space over a year's time using only the physics that worked for periods of an hour and less in prior publications. All portions of the task were achieved, including the optional portion of determining a value for conductivity that best .t the data. Fortran statements were developed that are required for the NUMIT runs to work with this kind of data from space. In addition to developing the Fortran for NUMIT, simple correlations between the IDM pulsing history and the space radiation were observed because we now have a better characterization of the space radiation. The study showed that: (1) the new methods for measurement of charge storage and conduction in insulators provide the correct values to use for prediction of charging and pulsing in space; (2) the methods in NUMIT that worked well for time durations less than hours now work well for durations of months; (3) an average spectrum such as AE8 is probably not a good guide for predicting pulsing in space one must take time dependence into account in order to understand insulator pulsing; and (4) the old method for predicting pulse rates in space that was based on the CRRES data could be improved to include dependencies on material parameters.

  20. 33 CFR 165.T11-568 - Safety Zone; San Diego Symphony Summer POPS Fireworks 2013 Season, San Diego, CA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Summer POPS Fireworks 2013 Season, San Diego, CA. 165.T11-568 Section 165.T11-568 Navigation and... Areas Eleventh Coast Guard District § 165.T11-568 Safety Zone; San Diego Symphony Summer POPS Fireworks... fireworks barge in approximate position 32°42′16″ N, 117°09′59″ W. (b) Enforcement period. This rule will...

  1. Multi-peptide nLC-PC-IDMS-SRM-based assay for the quantification of biomarkers in the chicken ovarian cancer model.

    PubMed

    Andrews Kingon, Genna L; Petitte, James N; Muddiman, David C; Hawkridge, Adam M

    2013-06-15

    A novel form of ovomacroglobulin/ovostatin (OVOS2) predicted from EST data was previously identified in the chicken ovarian cancer model using a mass spectrometry-based shotgun label-free proteomics strategy. The quantitative label-free data from plasma showed a significant increase over time with the spontaneous onset and progression of ovarian cancer making it a potential protein biomarker for further study. Two other proteins of interest identified from this initial study included vitellogenin-1 (Vit-1), a lipid-transport protein tied to egg production, and transthyretin (TTR), a retinol binding transport protein currently used in the clinical management of ovarian cancer. A multiplexed protein cleavage isotope dilution mass spectrometry (PC-IDMS) assay was developed to quantify OVOS2, Vit-1, and TTR by selected reaction monitoring (SRM). A total of 6 stable isotope labeled (SIL) peptide standards were used in the assay with three tryptic peptides from OVOS2, one for Vit-1, and two for TTR. The assay was developed for use with un-depleted raw plasma combined with the filter assisted sample preparation (FASP) method and its use was also demonstrated for matched ovary tissue samples. The PC-IDMS data for the two TTR peptides did not correlate with each other with more than a 10-fold difference in concentration for all 5 time points measured. The PC-IDMS data from the longitudinal plasma samples correlated well for OVOS2 and Vit-1 whereas TTR was inconclusive. Interestingly, the absolute amount for one of the OVOS2 SIL peptides was 2-fold less compared with the other two SIL peptides. These data illustrate the successes and challenges of qualifying quantitative levels of proteins from an in-gel digestion sample preparation followed by LC-MS/MS (GeLC) label-free discovery-based approach to a targeted SRM-based quantitative assay in plasma and tissues.

  2. Full method validation for the determination of hexachlorobenzene and hexachlorobutadiene in fish tissue by GC-IDMS.

    PubMed

    Majoros, Laszlo I; Lava, Roberto; Ricci, Marina; Binici, Burcu; Sandor, Florian; Held, Andrea; Emons, Hendrik

    2013-11-15

    This paper summarizes the validation strategy and the results obtained for the simultaneous determination of hexachlorobenzene (HCB) and hexachlorobutadiene (HCBD) in fish tissue with a maximum of about 10% m/m fat content using a GC-IDMS technique. The method is applicable for the determination of HCB and HCBD at trace levels in different kinds of fish tissue samples in accordance with the requirements of the EU Directive 2008/105/EC establishing Environmental Quality Standard (EQS) levels for biota in aquatic ecosystems (10 ng/g for HCB and 55 ng/g for HCBD). The method validation aimed to assess performance parameters such as linearity, limit of detection/limit of quantification (LOD/LOQ), trueness, selectivity, intermediate precision, repeatability, stability of the extracts and robustness. The validation experiments have been performed by using uncontaminated fish tissue. Trueness was evaluated by using a certified reference material (NIST SRM 1947) (where applicable) and by the standard addition method. Very good linear signal-concentration curves were obtained for both analytes over the whole range of calibration. The repeatability and the intermediate precision of the method, expressed as relative standard deviation (RSD) and calculated at the EQS level, were estimated to be below 3% both for HCB and HCBD. The limits of quantification were 3.7 ng/g for HCB and 15.7 ng/g for HCBD in the fish. An uncertainty budget for the measurement of both HCB and HCBD in fish at about the EQS levels, applying the described method, has been established in the order of 10%. The analytical method and its performance characteristics take into account the requirements of EU Directive 2009/90/EC regarding the establishment of minimum performance criteria for the methods of analysis to be used in the water monitoring activity of the Water Framework Directive. Finally, the validated method was successfully tested on contaminated Silurus glanis from Ebro River (Spain). The method

  3. Description and evaluation of a hearing conservation program in use in a professional symphony orchestra.

    PubMed

    O'Brien, Ian; Driscoll, Tim; Ackermann, Bronwen

    2015-04-01

    Professional orchestral musicians risk permanent hearing loss while playing their instruments. Protecting the hearing of these musicians in the workplace is critical to their ongoing ability to play their instruments, but typical workplace hearing conservation measures can have very damaging effects on the product (music) and the musicians' abilities to hear one another sufficiently. To enable effective intervention, orchestras as employers must encourage engagement with hearing protection programs and implement controls while preserving the integrity of the music. To achieve this, typical approaches used in other industries must be redesigned to suit this unique workplace. In response to these challenges, the Queensland Symphony Orchestra (Brisbane, Australia) introduced a comprehensive hearing conservation strategy in 2005 based upon best practice at the time. This strategy-which has been regularly refined-continues to be implemented on a daily basis. This investigation aimed to assess the successes, difficulties, and practical viability of the program. To achieve this a process evaluation was carried out, incorporating archival analyses, player and management focus groups, and an interview with the program's administrator. Results show the program has successfully become integrated into the orchestra's and the musicians' daily operations and significantly contributes to managing the risk of hearing loss in this population. While there is room for improvement in the orchestra's approach-particularly regarding usable personal protective devices and improved education and training, results are encouraging. This study provides a basis for those wishing to implement or evaluate similar paradigms.

  4. “Nodal Gap” induced by the incommensurate diagonal spin density modulation in underdoped high- id='M1'>Tc superconductors

    SciTech Connect

    Zhou, Tao; Gao, Yi; Zhu, Jian -Xin

    2015-03-07

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the id='M2'>d-wave nodal lines (nodal gap) contrasts the common understanding of the id='M3'>d-wave pairing symmetry, which challenges the present theories for the high-id='M4'>Tcsuperconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-id='M5'>Tcsuperconductors.

  5. 33 CFR 165.T08-0238 - Safety Zone; Cincinnati Symphony Orchestra Fireworks Displays Ohio River, Mile 460.9-461.3...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety Zone; Cincinnati Symphony Orchestra Fireworks Displays Ohio River, Mile 460.9-461.3, Cincinnati, OH. 165.T08-0238 Section 165.T08-0238... Fireworks Displays Ohio River, Mile 460.9-461.3, Cincinnati, OH. (a) Location. The following area is...

  6. Prevalence and consequences of musculoskeletal symptoms in symphony orchestra musicians vary by gender: a cross-sectional study

    PubMed Central

    2011-01-01

    Background Musculoskeletal symptoms are common in the neck, back, and upper limbs amongst musicians. Playing-related musculoskeletal disorders have been found to range from 32% to 87% with a tendency for female musicians to have more problems than males. Studies of musculoskeletal problems in instrumentalists have generally involved pre-professional musicians or populations comprising musicians of different levels. The objective of this study was therefore to investigate the prevalence, duration and consequences of musculoskeletal symptoms in professional symphony orchestra musicians. Methods A cross-sectional questionnaire study. The study population comprised of 441 musicians from six Danish symphony orchestras; 342 (78%) completed the questionnaire. Results During the last year 97% of the women and 83% of the men experienced symptoms in at least one of nine anatomic regions (neck, upper and lower back, shoulders, elbows, and hands and wrists). 86% of the women and 67% of the men experienced symptoms for more than seven days, while 63% of the women and 49% of the men had symptoms for more than 30 days. Woodwind players had a lower risk for musculoskeletal symptoms and a lower risk for the consequences. Among consequences were changed way of playing, reported by 73% of the musicians, difficulty in daily activities at home, reported by 55%, and difficulty in sleeping, reported by 49%. Their health behaviour included taking paracetamol as the most used analgesic, while physiotherapists and general practitioners were reported as the most consulted health care professionals concerning musculoskeletal problems. Results regarding symptoms in six anatomic regions were compared to results for a sample of the general Danish workforce. Symptoms were more frequent in musicians and lasted longer than in the general workforce. This applied to both genders. Conclusions Within the last year most symphony orchestra musicians experienced musculoskeletal symptoms in the neck, back

  7. Effects of particle size, helium gas pressure and microparticle dose on the plasma concentration of indomethacin after bombardment of indomethacin-loaded poly-L-lactic acid microspheres using a Helios gun system.

    PubMed

    Uchida, Masaki; Natsume, Hideshi; Kobayashi, Daisuke; Sugibayashi, Kenji; Morimoto, Yasunori

    2002-05-01

    We investigated the effects of the particle size of indomethacin-loaded poly-L-lactic acid microspheres (IDM-loaded PLA MS), the helium pressure used to accelerate the particles, and the bombardment dose of PLA MS on the plasma concentration of IDM after bombarding with IDM-loaded PLA MS of different particle size ranges, 20-38, 44-53 and 75-100 microm, the abdomen of hairless rats using the Helios gene gun system (Helios gun system). Using larger particles and a higher helium pressure, produced an increase in the plasma IDM concentration and the area under the plasma concentration-time curve (AUC) and resultant F (relative bioavailability with respect to intracutaneous injection) of IDM increased by an amount depending on the particle size and helium pressure. Although a reduction in the bombardment dose led to a decrease in C(max) and AUC, F increased on decreasing the bombardment dose. In addition, a more efficient F was obtained after bombarding with IDM-loaded PLA MS of 75-100 microm in diameter at each low dose in different sites of the abdomen compared with that after bolus bombardment with a high dose (dose equivalent). These results suggest that the bombardment injection of drug-loaded microspheres by the Helios gun system is a very useful tool for delivering a variety of drugs in powder form into the skin and systemic circulation.

  8. Integrated Distribution Management System for Alabama Principal Investigator

    SciTech Connect

    Schatz, Joe

    2013-03-31

    Southern Company Services, under contract with the Department of Energy, along with Alabama Power, Alstom Grid (formerly AREVA T&D) and others moved the work product developed in the first phase of the Integrated Distribution Management System (IDMS) from “Proof of Concept” to true deployment through the activity described in this Final Report. This Project – Integrated Distribution Management Systems in Alabama – advanced earlier developed proof of concept activities into actual implementation and furthermore completed additional requirements to fully realize the benefits of an IDMS. These tasks include development and implementation of a Distribution System based Model that enables data access and enterprise application integration.

  9. Philadelphia's New World Symphony.

    ERIC Educational Resources Information Center

    Roth, Edith Brill

    1980-01-01

    An outgrowth of a school for immigrants' children, the Philadelphia Settlement Music School offers music education to children of all races and classes, with the primary aim of teaching children to enjoy and understand music throughout their lives. (SK)

  10. A Symphony of Software.

    ERIC Educational Resources Information Center

    Currents, 2002

    2002-01-01

    Offers a descriptive table of databases that help higher education institutions orchestrate advancement operations. Information includes vendor, contact, software, price, database engine/server platform, recommended reporting tools, record capacity, and client type. (EV)

  11. Symphony no. Alcuin's Riddle.

    NASA Astrophysics Data System (ADS)

    Veeneman, Curt H.

    Alcuin, an eighth century poet, mathematician, educator and cleric, was the foremost scholar of the Carolingian Renaissance. Indeed, he was Charlemagne's antidote to illiteracy in the middle ages. He also loved riddles. One of his riddles, a, favorite of mine, presents a ferrying problem: A man has a wolf, a goat, and a bundle of cabbages. He must cross a river, but his boat is so small that he can take only one of them at a time. For obvious reasons, he cannot leave the goat with the cabbages, nor the wolf with the goat. The question is how many crossings must he make. The solution to this riddle suggested an intriguing form to me: one that is not only rounded, but has palindromic characteristics. The concept of a time-space relationship informs the large-scale design of this work. I have made the audience the "river," allowing them to hear the solution to the riddle unfold--in the midst of the action. (And once an audience member solves the riddle he will have a sense of when the music will end!) The work is scored for an orchestra on stage and 15 soloists in the audience, who span the auditorium from the stage to the rear, and function as a medium by which the music crosses the audience-river.

  12. Development of an Integrated Distribution Management System

    SciTech Connect

    Schatz, Joe E.

    2010-10-20

    This final report details the components, functionality, costs, schedule and benefits of developing an Integrated Distribution Management System (IDMS) for power distribution system operation. The Distribution Automation (DA) and Supervisory Control and Data Acquisition (SCADA) systems used by electric power companies to manage the distribution of electric power to retail energy consumers are vital components of the Nation’s critical infrastructure. Providing electricity is an essential public service and a disruption in that service, if not quickly restored, could threaten the public safety and the Nation’s economic security. Our Nation’s economic prosperity and quality of life have long depended on the essential services that utilities provide; therefore, it is necessary to ensure that electric utilities are able to conduct their operations safely and efficiently. A fully integrated technology of applications is needed to link various remote sensing, communications and control devices with other information tools that help guide Power Distribution Operations personnel. A fully implemented IDMS will provide this, a seamlessly integrated set of applications to raise electric system operating intelligence. IDMS will enhance DA and SCADA through integration of applications such as Geographic Information Systems, Outage Management Systems, Switching Management and Analysis, Operator Training Simulator, and other Advanced Applications, including unbalanced load flow and fault isolation/service restoration. These apps are capable of utilizing and obtaining information from appropriately installed DER, and by integrating disparate systems, the Distribution Operators will benefit from advanced capabilities when analyzing, controlling and operating the electric system.

  13. Data base design for a worldwide multicrop information system

    NASA Technical Reports Server (NTRS)

    Driggers, W. G.; Downs, J. M.; Hickman, J. R.; Packard, R. L. (Principal Investigator)

    1979-01-01

    A description of the USDA Application Test System data base design approach and resources is presented. The data is described in detail by category, with emphasis on those characteristics which influenced the design most. It was concluded that the use of a generalized data base in support of crop assessment is a sound concept. The IDMS11 minicomputer base system is recommended for this purpose.

  14. An Efficient Method to Calculate the Failure Rate of Dynamic Systems with Random Parameters using the Total Probability Theorem

    DTIC Science & Technology

    2015-05-12

    using a vibratory system . Our approach can be easily extended to non-stationary Gaussian input processes. Introduction The response of a vibratory...Page 1 of 9 15IDM-0105 An Efficient Method to Calculate the Failure Rate of Dynamic Systems with Random Parameters using the Total Probability...failure rate of a linear vibratory system with random parameters excited by stationary Gaussian processes. The response of such a system is non

  15. (Integrated Diffractive Mirrors (IDM) Ion Traps)

    DTIC Science & Technology

    2014-03-04

    trap electrodes. Fluorescence from trapped ions is collected at high solid angle coverage for subsequent coupling into optical fiber (not shown). 2-6...integrated optics and fiber ribbon. The width of all optics was set by the ground electrode width of 80 μm. Since the trapping potential minimum was...signal. Thermal relaxation of the cables during the bake actually forced the trap carrier up and out of the socket on two occasions. We installed a

  16. Telecommunications issues of intelligent database management for ground processing systems in the EOS era

    NASA Technical Reports Server (NTRS)

    Touch, Joseph D.

    1994-01-01

    Future NASA earth science missions, including the Earth Observing System (EOS), will be generating vast amounts of data that must be processed and stored at various locations around the world. Here we present a stepwise-refinement of the intelligent database management (IDM) of the distributed active archive center (DAAC - one of seven regionally-located EOSDIS archive sites) architecture, to showcase the telecommunications issues involved. We develop this architecture into a general overall design. We show that the current evolution of protocols is sufficient to support IDM at Gbps rates over large distances. We also show that network design can accommodate a flexible data ingestion storage pipeline and a user extraction and visualization engine, without interference between the two.

  17. New World Symphony and Discord

    ERIC Educational Resources Information Center

    Horowitz, Joseph

    2008-01-01

    In this article, the author features the life and works of Antonin Dvorak, a Czech classical musician. In the throes of a New World epiphany, Dvorak has espoused a future for American music based on "negro melodies." For three years, beginning in the fall of 1892, Dvorak found himself embroiled in a sustained and often bitter debate over issues of…

  18. ADA interpretative system for image algebra

    NASA Astrophysics Data System (ADS)

    Murillo, Juan J.; Wilson, Joseph N.

    1992-06-01

    An important research problem in image processing is to find appropriate tools to support algorithm development. There have been efforts to build algorithm development support systems for image algebra in several languages, but these systems still have the disadvantage of the time consuming algorithm development style associated with compilation-oriented programming. This paper starts with a description of the Run-Time Support Library (RTSL), which serves as the base for executing programs on both the Image Algebra Ada Translator (IAAT) and Image Algebra Ada Interpreter (IAAI). A presentation on the current status of IAAT and its capabilities is followed by a brief introduction to the utilization of the Image Display Manager (IDM) for image manipulation and analysis. We then discuss in detail the current development stage of IAAI and its relation with RTSL and IDM. The last section describes the design of a syntax-directed graphical user interface for IAAI. We close with an analysis of the current performance of IAAI, and future trends are discussed. Appendix A gives a brief introduction to Image Algebra (IA), and in Appendix B the reader is presented to the Image Algebra Ada (IAA) grammar.

  19. Development of a measurement system for certifying ethanol mass fraction in aqueous solutions.

    PubMed

    Burke, Daniel G; Mackay, Lindsey G; Myors, Richard; Cuthbertson, Judith; Richardson, Jeremy; Sousou, Nigel; Saxby, David; Askew, Shane; O'Brien, Rebecca

    2009-07-15

    In response to the sovereign requirement for national standards the National Measurement Institute, Australia (NMIA) has developed a measuring system using isotope dilution mass spectrometry (IDMS) to certify forensic aqueous ethanol solutions. NMIA participated in an international study, CCQM-K27, organized under the auspices of the International Committee for Weights and Measures to compare our measuring system with the techniques being used for certifying aqueous ethanol solutions in other metrology institutes. This comparison provided objective evidence that the measuring system developed was fit for the purpose of certifying aqueous ethanol solutions that ranged in concentration from 0.8 mg/g to 120 mg/g. A complete measurement uncertainty budget is presented and shows that the largest contribution to measurement uncertainty was from method precision followed by the contribution from the calibration solution. The fundamental technology of the measuring system was gas chromatography of the aqueous ethanol solutions using porous layer open tubular columns, and this effectively produced peak area measurements with both GC/MS and GC-FID. It was found that deactivation of the chromatographic system was critical for obtaining reproducible peak shapes and peak area measurements. A range of measuring systems, all using this gas chromatographic technology, was investigated. When conditions were carefully controlled there was no difference in measurement results from GC-IDMS, GC/MS or GC-FID. There was also no difference in results from on-column or split injection systems. A significant issue with the IDMS system was the fragmentation of 13C2-ethanol to produce an ion with the same mass as the molecular ion of ethanol which lead to isobaric interference; careful measurement of this fragmentation ratio was necessary to calculate accurate mass fraction values. NMIA has adopted the GC-IDMS split measuring system to certify aqueous ethanol solutions for Australian legal

  20. Knowledge-based diagnosis for aerospace systems

    NASA Technical Reports Server (NTRS)

    Atkinson, David J.

    1988-01-01

    The need for automated diagnosis in aerospace systems and the approach of using knowledge-based systems are examined. Research issues in knowledge-based diagnosis which are important for aerospace applications are treated along with a review of recent relevant research developments in Artificial Intelligence. The design and operation of some existing knowledge-based diagnosis systems are described. The systems described and compared include the LES expert system for liquid oxygen loading at NASA Kennedy Space Center, the FAITH diagnosis system developed at the Jet Propulsion Laboratory, the PES procedural expert system developed at SRI International, the CSRL approach developed at Ohio State University, the StarPlan system developed by Ford Aerospace, the IDM integrated diagnostic model, and the DRAPhys diagnostic system developed at NASA Langley Research Center.

  1. Performance of a HPGe System for Surface and Container Measurements - 13582

    SciTech Connect

    Twomey, Timothy R.; Keyser, Ronald M.

    2013-07-01

    The decommissioning of a nuclear facility or post-accident cleanup is an immense engineering effort requiring an array of specialist tools and techniques. The decommissioning and cleanup activities generate large quantities of low activity waste. For economic disposal, it is desirable to certify the waste as suitable for free release. Every container must be assayed to a sufficient degree of accuracy and sensitivity so that it may be certified to be or not to be suitable for 'free release'. In a previous work, the performance of a highly-automated system for free release of large numbers of containers was presented in which the spectroscopy hardware comprised four ORTEC Interchangeable Detector Module (IDM) mechanically cooled HPGe spectrometers in conjunction with ORTEC ISOPlus waste assay software. It was shown that the system was capable of assaying large containers to free release levels in reasonable measurement times. Not all operations have enough waste to justify an automated system or rapid assay results may be required, perhaps in a remote location. To meet this need, a new mobile system has been developed for the assay of smaller objects (drums, boxes, and surfaces) In-Situ. The system incorporates the latest generation IDM-200 and ISOPlus software and a new variant of the ISOCart hardware. This paper will describe the system and performance. (authors)

  2. The symphony of autophagy and calcium signaling.

    PubMed

    Yao, Zhiyuan; Klionsky, Daniel J

    2015-01-01

    Posttranslational regulation of macroautophagy (hereafter autophagy), including phosphorylating and dephosphorylating components of the autophagy-related (Atg) core machinery and the corresponding upstream transcriptional factors, is important for the precise modulation of autophagy levels. Several kinases that are involved in phosphorylating autophagy-related proteins have been identified in both yeast and mammalian cells. However, there has been much less research published with regard to the identification of the complementary phosphatases that function in autophagy. A recent study identified PPP3/calcineurin, a calcium-dependent phosphatase, as a regulator of autophagy, and demonstrated that one of the key targets of PPP3/calcineurin is TFEB, a master transcriptional factor that controls autophagy and lysosomal function in mammalian cells.

  3. Lipid - Motor Interactions: Soap Opera or Symphony?

    PubMed

    Pathak, Divya; Mallik, Roop

    2016-09-30

    Intracellular transport of organelles can be driven by multiple motor proteins that bind to the lipid membrane of the organelle and work as a team. We review present knowledge on how lipids orchestrate the recruitment of motors to a membrane. Looking beyond recruitment, we also discuss how heterogeneity and local mechanical properties of the membrane may influence function of motor-teams. These issues gain importance because phagocytosed pathogens use lipid-centric strategies to manipulate motors and survive in host cells.

  4. Spacetime Symphony: APOD and Gravitational Waves

    NASA Astrophysics Data System (ADS)

    Cominsky, Lynn R.; Simonnet, Aurore; LIGO-Virgo Scientific Collaboration

    2017-01-01

    In 1915, Albert Einstein published his General Theory of Relativity. In this theory, gravity is not a force, but a property of space and time in the presence of massive objects. A century later, on September 14, 2015, the Laser Interferometer Gravitational-wave Observatory (LIGO) received the first confirmed gravitational wave signals. Now known as GW150914, the event represents the coalescence of two distant black holes that were previously in mutual orbit. The LIGO-Virgo Scientific Collaboration planned a detailed social media strategy to publicize the February 11, 2016 press conference that announced this discovery. Astronomy Picture of the Day (APOD) was a major factor in disseminating the now iconic imagery that was developed, and the LVC worked closely with APOD to ensure that the secrecy would be maintained throughout the press embargo period. Due to the success of our efforts, we repeated the process for the AAS press conference that announced GW151226, the second confirmed gravitational wave event. We have also repurposed the APOD imagery for an online course for community college instructors, as well as in a poster that will be available through CPEPphysics.org (Contemporary Physics Education Project).

  5. Molecular orchestration of the hepatic circadian symphony.

    PubMed

    Albrecht, Urs

    2006-01-01

    The circadian clock determines the rhythmic expression of many different genes throughout a 24-hour period. A recent study investigating the circadian regulation of liver proteins reveals multiple levels of regulation, including transcriptional, post-transcriptional and post-translational mechanisms.

  6. The second generation intelligent user interface for the crustal dynamics data information system. [for nasa space missions

    NASA Technical Reports Server (NTRS)

    Short, Nicholas, Jr.; Wattawa, Scott L.

    1988-01-01

    For the past decade, operations and research projects that support a major portion of NASA's overall mission have experienced a dramatic increase in the volume of generated data and resultant information that is unparalleled in the history of the agency. The effect of such an increase is that most of the science and engineering disciplines are undergoing an information glut, which has occurred, not only because of the amount, but also because of the type of data being collected. This information glut is growing exponentially and is expected to grow for the foreseeable future. Consequently, it is becoming physically and intellectually impossible to identify, access, modify, and analyze the most suitable information. Thus, the dilemma arises that the amount and complexity of information has exceeded and will continue to exceed, using present information systems, the ability of all the scientists and engineers to understand and take advantage of this information. As a result of this information problem, NASA has initiated the Intelligent Data Management (IDM) project to design and develop Advanced Information Management (IDM) project to design and develop Advanced Information Management Systems (AIMS). The first effort of the Project was the prototyping of an Intelligent User Interface (IUI) to an operational scientific database using expert systems, natural language processing, and graphics technologies. An overview of the IUI formulation and development for the second phase is presented.

  7. Description of data base management systems activities

    NASA Technical Reports Server (NTRS)

    1983-01-01

    One of the major responsibilities of the JPL Computing and Information Services Office is to develop and maintain a JPL plan for providing computing services to the JPL management and administrative community that will lead to improved productivity. The CISO plan to accomplish this objective has been titled 'Management and Administrative Support Systems' (MASS). The MASS plan is based on the continued use of JPL's IBM 3032 Computer system for administrative computing and for the MASS functions. The current candidate administrative Data Base Management Systems required to support the MASS include ADABASE, Cullinane IDMS and TOTAL. Previous uses of administrative Data Base Systems have been applied to specific local functions rather than in a centralized manner with elements common to the many user groups. Limited capacity data base systems have been installed in microprocessor based office automation systems in a few Project and Management Offices using Ashton-Tate dBASE II. These experiences plus some other localized in house DBMS uses have provided an excellent background for developing user and system requirements for a single DBMS to support the MASS program.

  8. Workflow-Management für organisationsübergreifende Datenübertragung am Beispiel des E-Learning-Systems der TUM

    NASA Astrophysics Data System (ADS)

    Boursas, Latifa

    In diesem Paper werden im ersten Schritt die Voraussetzungen und Anforderungen für Workflow-Management zur Bereitstellung einer organisationsübergreifenden Datenübertragung ausgeführt. Weiter werden auf einfache Art und Weise die Grundlagen des Identity Managements (IDM) und der Provisionierung von Zielsystemen erläutert sowie die technischen Lösungsideen für die genannten Anforderungen eingeführt. Am Beispiel des E-Learning-Systems der TU München zeigen wir zwei Lösungsansätze. Zu jedem Lösungsansatz werden die technischen Workflows genauer betrachtet und der Funktionsumfang erläutert. Ein paar Uses Cases bei den Datenkonvertierungen, die sich auf die verschiedenen Identity-Management-Schnittstellen beziehen werden auch präsentiert. Am Ende schließt ein Vergleich der beiden Lösungsansätze die Analyse ab.

  9. Identity and Access Management and Security in Higher Education.

    ERIC Educational Resources Information Center

    Bruhn, Mark; Gettes, Michael; West, Ann

    2003-01-01

    Discusses the drivers for an identity management system (IdM), components of this system, and its role within a school security strategy, focusing on: basic access management; requirements for access management; middleware support for an access management system; IdM implementation considerations (e.g., access eligibilities, authentication…

  10. Silos to Symphonies? Hopes and Challenges Implementing Multicultural Programme Infusion

    ERIC Educational Resources Information Center

    Liu, Laura B.; Milman, Natalie B.

    2013-01-01

    The need to infuse multicultural education (ME) across teacher preparation programmes is well documented by research, yet institutions are at very different stages in this endeavour. While most programmes demonstrate a segregated approach to ME, confining diversity to specialty courses, ME programme infusion places diversity, equity and social…

  11. A Symphony for Your Brain: A Psychological Research Methods Case

    ERIC Educational Resources Information Center

    Hager, Lisa D.

    2004-01-01

    This article presents a case study where students examine an advertisement claiming that listening to classical music in an advertised CD set will enhance their cognitive skills and creativity. Students evaluate the claims and evidence cited to support them and then determine how they might independently verify the claims. The author states that…

  12. Reflections on Measuring Thinking, while Listening to Mozart's "Jupiter" Symphony.

    ERIC Educational Resources Information Center

    Wasserman, Selma

    1989-01-01

    Reflects on educators' current preoccupation with assessment of higher order thinking skills. Easy-to-mark, forced-choice, pencil-and-paper tests with single numerical scores may trivialize the wonderful complexity of human capabilities. Includes 17 references. (MLH)

  13. The seminal symphony: how to compose an ejaculate

    PubMed Central

    Perry, Jennifer C.; Sirot, Laura; Wigby, Stuart

    2016-01-01

    Ejaculates are fundamental to fitness in sexually-reproducing animals: males gain all their direct fitness via the ejaculate and females require ejaculates to reproduce. Both sperm and non-sperm components of the ejaculate (including parasperm, seminal proteins, water and macromolecules) play vital roles in post-copulatory sexual selection and conflict, processes that can potentially drive rapid evolutionary change and reproductive isolation. Here, we assess the increasing evidence that considering ejaculate composition as a whole – and potential trade-offs among ejaculate components – has important consequences for predictions about male reproductive investment and female responses to ejaculates. We review current theory and empirical work, and detail how social and environmental effects on ejaculate composition have potentially far-reaching fitness consequences for both sexes. PMID:23582755

  14. Integrating NASA's Land Analysis System (LAS) image processing software with an appropriate Geographic Information System (GIS): A review of candidates in the public domain

    NASA Technical Reports Server (NTRS)

    Rochon, Gilbert L.

    1989-01-01

    A user requirements analysis (URA) was undertaken to determine and appropriate public domain Geographic Information System (GIS) software package for potential integration with NASA's LAS (Land Analysis System) 5.0 image processing system. The necessity for a public domain system was underscored due to the perceived need for source code access and flexibility in tailoring the GIS system to the needs of a heterogenous group of end-users, and to specific constraints imposed by LAS and its user interface, Transportable Applications Executive (TAE). Subsequently, a review was conducted of a variety of public domain GIS candidates, including GRASS 3.0, MOSS, IEMIS, and two university-based packages, IDRISI and KBGIS. The review method was a modified version of the GIS evaluation process, development by the Federal Interagency Coordinating Committee on Digital Cartography. One IEMIS-derivative product, the ALBE (AirLand Battlefield Environment) GIS, emerged as the most promising candidate for integration with LAS. IEMIS (Integrated Emergency Management Information System) was developed by the Federal Emergency Management Agency (FEMA). ALBE GIS is currently under development at the Pacific Northwest Laboratory under contract with the U.S. Army Corps of Engineers' Engineering Topographic Laboratory (ETL). Accordingly, recommendations are offered with respect to a potential LAS/ALBE GIS linkage and with respect to further system enhancements, including coordination with the development of the Spatial Analysis and Modeling System (SAMS) GIS in Goddard's IDM (Intelligent Data Management) developments in Goddard's National Space Science Data Center.

  15. IDM Supervision: An Integrated Developmental Model for Supervising Counselors and Therapists.

    ERIC Educational Resources Information Center

    Stoltenberg, Cal D.; McNeill, Brian; Delworth, Ursula

    Understanding change over time in one's ability to function as a professional is fundamental in the practice of clinical supervision. Drawing on developmental models of human behavior, a model of the development over time of therapy practice is presented. Specific domains of clinical practice and overriding structures that provide markers in…

  16. A spatial data handling system for retrieval of images by unrestricted regions of user interest

    NASA Technical Reports Server (NTRS)

    Dorfman, Erik; Cromp, Robert F.

    1992-01-01

    The Intelligent Data Management (IDM) project at NASA/Goddard Space Flight Center has prototyped an Intelligent Information Fusion System (IIFS), which automatically ingests metadata from remote sensor observations into a large catalog which is directly queryable by end-users. The greatest challenge in the implementation of this catalog was supporting spatially-driven searches, where the user has a possible complex region of interest and wishes to recover those images that overlap all or simply a part of that region. A spatial data management system is described, which is capable of storing and retrieving records of image data regardless of their source. This system was designed and implemented as part of the IIFS catalog. A new data structure, called a hypercylinder, is central to the design. The hypercylinder is specifically tailored for data distributed over the surface of a sphere, such as satellite observations of the Earth or space. Operations on the hypercylinder are regulated by two expert systems. The first governs the ingest of new metadata records, and maintains the efficiency of the data structure as it grows. The second translates, plans, and executes users' spatial queries, performing incremental optimization as partial query results are returned.

  17. The second generation intelligent user interface for the crustal dynamics data information system

    NASA Technical Reports Server (NTRS)

    Short, Nicholas, Jr.; Wattawa, Scott L.

    1988-01-01

    For the past decade, operations and research projects that support a major portion of NASA's overall mission have experienced a dramatic increase in the volume of generated data and resultant information that is unparalleled in the history of the agency. The effect of such an increase is that most of the science and engineering disciplines are undergoing an information glut, which has occurred, not only because of the amount, but also because of the type of data being collected. This information glut is growing exponentially and is expected to grow for the foreseeable future. Consequently, it is becoming physically and intellectually impossible to identify, access, modify, and analyze the most suitable information. Thus, the dilemma arises that the amount and complexity of information has exceeded and will continue to exceed, using present information systems, the ability of all the scientists and engineers to understand and take advantage of this information. As a result of this information problem, NASA has initiated the Intelligent Data Management (IDM) project to design and develop Advanced Information Management Systems (AIMS). The first effort of the Project was the prototyping of an Intelligent User Interface (IUI) to an operational scientific database using expert systems, natural language processing, and graphics technologies. An overview of the IUI formulation and development for the second phase is presented.

  18. Adaptation of antenna profiles for control of MR guided hyperthermia (HT) in a hybrid MR-HT system

    SciTech Connect

    Weihrauch, Mirko; Wust, Peter; Weiser, Martin; Nadobny, Jacek; Eisenhardt, Steffen; Budach, Volker; Gellermann, Johanna

    2007-12-15

    A combined numerical-experimental iterative procedure, based on the Gauss-Newton algorithm, has been developed for control of magnetic resonance (MR)-guided hyperthermia (HT) applications in a hybrid MR-HT system BSD 2000 3D-MRI. In this MR-HT system, composed of a 3-D HT applicator Sigma-Eye placed inside a tunnel-type MR tomograph Siemens MAGNETOM Symphony (1.5 T), the temperature rise due to the HT radiation can be measured on-line in three dimensions by use of the proton resonance frequency shift (PRFS) method. The basic idea of our iterative procedure is the improvement of the system's characterization by a step-by-step modification of the theoretical HT antenna profiles (electric fields radiated by single antennas). The adaptation of antenna profiles is efficient if the initial estimates are radiation fields calculated from a good a priori electromagnetic model. Throughout the iterative procedure, the calculated antenna fields (FDTD) are step-by-step modified by comparing the calculated and experimental data, the latter obtained using the PRFS method. The procedure has been experimentally tested on homogeneous and inhomogeneous phantoms. It is shown that only few comparison steps are necessary for obtaining a dramatic improvement of the general predictability and quality of the specific absorption rate (SAR) inside the MR-HT hybrid system.

  19. The development of a prototype intelligent user interface subsystem for NASA's scientific database systems

    NASA Technical Reports Server (NTRS)

    Campbell, William J.; Roelofs, Larry H.; Short, Nicholas M., Jr.

    1987-01-01

    The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has as one of its components the development of an Intelligent User Interface (IUI).The intent of the latter is to develop a friendly and intelligent user interface service that is based on expert systems and natural language processing technologies. The purpose is to support the large number of potential scientific and engineering users presently having need of space and land related research and technical data but who have little or no experience in query languages or understanding of the information content or architecture of the databases involved. This technical memorandum presents prototype Intelligent User Interface Subsystem (IUIS) using the Crustal Dynamics Project Database as a test bed for the implementation of the CRUDDES (Crustal Dynamics Expert System). The knowledge base has more than 200 rules and represents a single application view and the architectural view. Operational performance using CRUDDES has allowed nondatabase users to obtain useful information from the database previously accessible only to an expert database user or the database designer.

  20. Pilot scale processing of simulated Savannah River Site high level radioactive waste

    SciTech Connect

    Hutson, N.D.; Zamecnik, J.R.; Ritter, J.A.; Carter, J.T.

    1991-01-01

    The Savannah River Laboratory operates the Integrated DWPF Melter System (IDMS), which is a pilot-scale test facility used in support of the start-up and operation of the US Department of Energy's Defense Waste Processing Facility (DWPF). Specifically, the IDMS is used in the evaluation of the DWPF melter and its associated feed preparation and offgass treatment systems. This article provides a general overview of some of the test work which has been conducted in the IDMS facility. The chemistry associated with the chemical treatment of the sludge (via formic acid adjustment) is discussed. Operating experiences with simulated sludge containing high levels of nitrite, mercury, and noble metals are summarized.

  1. Robotically assisted MRgFUS system

    NASA Astrophysics Data System (ADS)

    Jenne, Jürgen W.; Krafft, Axel J.; Maier, Florian; Rauschenberg, Jaane; Semmler, Wolfhard; Huber, Peter E.; Bock, Michael

    2010-03-01

    Magnetic resonance imaging guided focus ultrasound surgery (MRgFUS) is a highly precise method to ablate tissue non-invasively. The objective of this ongoing work is to establish an MRgFUS therapy unit consisting of a specially designed FUS applicator as an add-on to a commercial robotic assistance system originally designed for percutaneous needle interventions in whole-body MRI systems. The fully MR compatible robotic assistance system InnoMotion™ (Synthes Inc., West Chester, USA; formerly InnoMedic GmbH, Herxheim, Germany) offers six degrees of freedom. The developed add-on FUS treatment applicator features a fixed focus ultrasound transducer (f = 1.7 MHz; f' = 68 mm, NA = 0.44, elliptical shaped -6-dB-focus: 8.1 mm length; O/ = 1.1 mm) embedded in a water-filled flexible bellow. A Mylar® foil is used as acoustic window encompassed by a dedicated MRI loop coil. For FUS application, the therapy unit is directly connected to the head of the robotic system, and the treatment region is targeted from above. A newly in-house developed software tool allowed for complete remote control of the MRgFUS-robot system and online analysis of MRI thermometry data. The system's ability for therapeutic relevant focal spot scanning was tested in a closed-bore clinical 1.5 T MR scanner (Magnetom Symphony, Siemens AG, Erlangen, Germany) in animal experiments with pigs. The FUS therapy procedure was performed entirely under MRI guidance including initial therapy planning, online MR-thermometry, and final contrast enhanced imaging for lesion detection. In vivo trials proved the MRgFUS-robot system as highly MR compatible. MR-guided focal spot scanning experiments were performed and a well-defined pattern of thermal tissue lesions was created. A total in vivo positioning accuracy of the US focus better than 2 mm was estimated which is comparable to existing MRgFUS systems. The newly developed FUS-robotic system offers an accurate, highly flexible focus positioning. With its access

  2. Lernen und Lehren von Mathematik-Analysen zum Unterrichtshandeln II - Band 6, IDM-Reihe, Untersuchungen zum Mathematikunterricht. (Learning and Teaching of Mathematics - Analysis of Instructional Actions II - Volume 6, IDM Series, Inquiries into Mathematics Instruction.)

    ERIC Educational Resources Information Center

    Bauersfeld, Heinrich; And Others

    This set of five papers, written in German with abstracts in English, was collected by the Institut fuer Didaktit der Mathematik (Institute for the Teaching of Mathematics) at the University of Bielefeld in West Germany. In the first paper, Bauersfeld considers domains of subjective experiences as the best issue for an interactive theory of…

  3. Glass melter off-gas system pluggages: Cause, significance, and remediation

    SciTech Connect

    Jantzen, C.M.

    1991-03-01

    Liquid high-level nuclear waste will be immobilized at the Savannah River Site (SRS) by vitrification in borosilicate glass. The glass will be produced in the Defense Waste Processing Facility (DWPF) where the glass will be poured into stainless steel canisters for eventual disposal in a geologic repository. Experimental glass melters used to develop the vitrification process for immobilization of the waste have experienced problems with pluggage of the off-gas line with solid deposits. Off-gas deposits from the DWPF 1/2 Scale Glass Melter (SGM) and the 1/10th scale Integrated DWPF Melter System (IDMS) were determined to be mixtures of alkali rich chlorides, sulfates, borates, and fluorides with entrained Fe{sub 2}O{sub 3}, spinel, and frit particles. The distribution and location of the alkali deposits throughout the off-gas system indicate that the deposits form by vapor-phase transport and condensation. Condensation of the alkali-rich phases cement the entrained particulates causing off-gas system pluggages. The identification of vapor phase transport as the operational mechanism causing off-gas system pluggage indicates that deposition can be effectively eliminated by increasing the off-gas velocity. Scale glass melter operating experience indicates that a velocity of >50 fps is necessary in order to transport the volatile species to the quencher to prevent having condensation occur in the off-gas line. Hotter off-gas line temperatures would retain the alkali compounds as vapors so that they would remain volatile until they reach the quencher. However, hotter off-gas temperatures can only be achieved by using less air/steam flow at the off-gas entrance, e.g. at the off-gas film cooler (OGFC). This would result in lower off-gas velocities. Maintaining a high velocity is, therefore, considered to be a more important criterion for controlling off-gas pluggage than temperature control. 40 refs., 16 figs., 5 tabs.

  4. Electrosprayed inulin microparticles for microbiota triggered targeting of colon.

    PubMed

    Jain, Arvind K; Sood, Vishesh; Bora, Meghali; Vasita, Rajesh; Katti, Dhirendra S

    2014-11-04

    Inulin, a naturally occurring polysaccharide, was acetylated to make it processable by electrospraying, a facile and single step method for microparticle fabrication. Electrospraying process parameters were optimized for fabrication of spherical and monodisperse indomethacin (IDM) loaded inulin acetate (INA) microparticles. The apparent entrapment efficiency of IDM was determined to be 100%, whereas working encapsulation efficiency was estimated to be 35.39 ± 1.63%. Differential scanning calorimetry and X-ray diffraction analysis confirmed molecular dispersion of IDM in an amorphous state within the INA matrix. Finally, the results from in vitro release study performed in simulated gastro-intestinal fluids demonstrated that IDM was released only in simulated colonic fluid that contained inulinase. Therefore, this study demonstrates that acetylation of inulin does not alter its susceptibility to inulinase and that microparticles fabricated from INA can be developed as a colon targeting drug delivery system.

  5. Investigating the Correlation between Miscibility and Physical Stability of Amorphous Solid Dispersions Using Fluorescence-Based Techniques.

    PubMed

    Tian, Bin; Tang, Xing; Taylor, Lynne S

    2016-11-07

    The purpose of this study was to investigate the feasibility of using a fluorescence-based technique to evaluate drug-polymer miscibility and to probe the correlation between miscibility and physical stability of amorphous solid dispersions (ASDs). Indomethacin-hydroxypropyl methylcellulose (IDM-HPMC), indomethacin-hydroxypropyl methylcellulose acetate succinate, and indomethacin-polyvinylpyrrolidone (IDM-PVP) were used as model systems. The miscibility of the IDM-polymer systems was evaluated by fluorescence spectroscopy, fluorescence imaging, differential scanning calorimetry (DSC), and infrared (IR) spectroscopy. The physical stability of IDM-polymer ASDs stored at 40 °C was evaluated using fluorescence imaging and X-ray diffraction (XRD). The experimentally determined miscibility limit of IDM with the polymers was 50-60%, 20-30%, and 70-80% drug loading for HPMC, HPMCAS, and PVP, respectively. The X-ray results showed that for IDM-HPMC ASDs, samples with a drug loading of less than 50% were maintained in amorphous form during the study period, while samples with drug loadings higher than 50% crystallized within 15 days. For IDM-HPMCAS ASDs, samples with drug loading less than 30% remained amorphous, while samples with drug loadings higher than 30% crystallized within 10 days. IDM-PVP ASDs were found to be resistant to crystallization for all compositions. Thus, a good correlation was observed between phase separation and reduced physical stability, suggesting that miscibility is indeed an important ASDs characteristic. In addition, fluorescence-based techniques show promise in the evaluation of drug-polymer miscibility.

  6. The Behavior and Effects of the Noble Metals in the DWPF Melter System

    SciTech Connect

    Smith, M.E.; Bickford, D.F.

    1997-11-30

    Governments worldwide have committed to stabilization of high-level nuclear waste (HLW) by vitrification to a durable glass form for permanent disposal. All of these nuclear wastes contain the fission-product noble metals: ruthenium, rhodium, and palladium. SRS wastes also contain natural silver from iodine scrubbers. Closely associated with the noble metals are the fission products selenium and tellurium which are chemical analogs of sulfur and which combine with noble metals to influence their behavior and properties. Experience has shown that these melt insoluble metals and their compounds tend to settle to the floor of Joule-heated ceramic melters. In fact, almost all of the major research and production facilities have experienced some operational problem which can be associated with the presence of dense accumulations of these relatively conductive metals and/or their compounds. In most cases, these deposits have led to a loss of production capability, in some cases, to the point that melter operation could not continue. HLW nuclear waste vitrification facilities in the United States are the Department of Energy`s Defense Waste Processing Facility (DWPF) at the Savannah River Site, the planned Hanford Waste Vitrification Plant (HWVP) at the Hanford Site and the operating West Valley Demonstration Project (WVDP) at West Valley, NY. The Integrated DWPF Melter System (IDMS) is a vitrification test facility at the Savannah River Technology Center (SRTC). It was designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas treatment systems. An extensive noble metals testing program was begun in 1990. The objectives of this task were to explore the effects of the noble metals on the DWPF melter feed preparation and waste vitrification processes. This report focuses on the vitrification portion of the test program.

  7. Development of an Integrated Robotic Radioisotope Identification and Location System

    DTIC Science & Technology

    2009-05-05

    1 1.2 GAMMA RAY SPECTROSCOPY TERMINOLOGY AND CONCEPTS ................ 3 1.3 SUMMARY OF THE ORTECK IDM HPGE...which is not closely guarded would be very hard to use in an RDD (Shea 2004). 3 1.2 GAMMA RAY SPECTROSCOPY TERMINOLOGY AND...1 1-2 HPGe Peak Detection Gamma Ray Spectrum (Delikat 2009)………..... ........................... 4 1-3 Comparison of NaI

  8. Liquid chromatography, chemical oxidation, and online carbon isotope dilution mass spectrometry as a universal quantification system for nonvolatile organic compounds.

    PubMed

    Díaz, Sergio Cueto; Encinar, Jorge Ruiz; Sanz-Medel, Alfredo; Alonso, J Ignacio García

    2013-02-05

    A procedure for the universal detection and quantification of polar organic compounds separated by liquid chromatography (LC) based on postcolumn carbon isotope dilution mass spectrometry (IDMS) was developed. The eluent from the LC column is mixed online with a continuous flow of (13)C-enriched sodium bicarbonate, and the sodium persulfate oxidation reaction in acidic media is employed to achieve isotope equilibration. All carbon-containing compounds eluting from the column are oxidized to (12)CO(2) and (13)CO(2), respectively, and the carbon dioxide is separated from the aqueous phase using a gas-permeable membrane. The gaseous carbon dioxide is then carried to the mass spectrometer for isotope ratio measurements. Different water-soluble organic compounds were evaluated using a flow injection configuration to assess the efficiency of the oxidation process. Most water-soluble organic compounds tested showed quantitative oxidation. However, chemical structures involving conjugated C═N double bounds and guanidinium-like structures were found to be resistant to the oxidation and were further studied. For this purpose, (13)C(1)-labeled creatine (with the isotopic label in the guanidinium group) was employed as model compound. Specific conditions for the quantitative oxidation of these compounds required lower flow rates and the addition of metallic catalysts. This novel approach was tested as a universal detection and quantification system for LC. A simple standard mixture of four amino acids was separated under 100% aqueous conditions and quantified without the need for specific standards with good accuracy and precision using potassium hydrogen phthalate as internal standard. The main field of application of the developed method is for the purity assessment of organic standards with direct traceability to the International System of Units (SI).

  9. Chronic obstructive pulmonary disease and glucose metabolism: a bitter sweet symphony

    PubMed Central

    2012-01-01

    Chronic obstructive pulmonary disease, metabolic syndrome and diabetes mellitus are common and underdiagnosed medical conditions. It was predicted that chronic obstructive pulmonary disease will be the third leading cause of death worldwide by 2020. The healthcare burden of this disease is even greater if we consider the significant impact of chronic obstructive pulmonary disease on the cardiovascular morbidity and mortality. Chronic obstructive pulmonary disease may be considered as a novel risk factor for new onset type 2 diabetes mellitus via multiple pathophysiological alterations such as: inflammation and oxidative stress, insulin resistance, weight gain and alterations in metabolism of adipokines. On the other hand, diabetes may act as an independent factor, negatively affecting pulmonary structure and function. Diabetes is associated with an increased risk of pulmonary infections, disease exacerbations and worsened COPD outcomes. On the top of that, coexistent OSA may increase the risk for type 2 DM in some individuals. The current scientific data necessitate a greater outlook on chronic obstructive pulmonary disease and chronic obstructive pulmonary disease may be viewed as a risk factor for the new onset type 2 diabetes mellitus. Conversely, both types of diabetes mellitus should be viewed as strong contributing factors for the development of obstructive lung disease. Such approach can potentially improve the outcomes and medical control for both conditions, and, thus, decrease the healthcare burden of these major medical problems. PMID:23101436

  10. Ascorbate oxidase is the potential conductor of a symphony of signaling pathways.

    PubMed

    De Tullio, Mario C; Guether, Mike; Balestrini, Raffaella

    2013-03-01

    The functional role of ascorbate oxidase (AO; EC 1.10.3.3) has never been fully explained so far, due to the difficulties in understanding the presence of an enzyme specifically oxidizing ascorbate with no obvious advantage, and the apparent disadvantage of lowering plant stress resistance as a consequence of ascorbate consumption. Here we suggest a complete change of perspective, by proposing an essential role of AO as a modulator of both ascorbate and oxygen content, with relevant implications related to signaling. By affecting the overall redox state, AO is actually involved in redox regulation in the extracellular matrix. In addition, AO can contribute to creating a hypoxic microenvironment, especially relevant in the maintenance of meristem identity and the establishment of mutualistic plant-microbe interactions. We also hypothesize the possible involvement of AO in the activation of a signaling cascade analogous to the mechanism of prolyl hydroxylases/Hypoxia Inducible Factors in animals.

  11. Rap-Interacting Proteins are Key Players in the Rap Symphony Orchestra.

    PubMed

    Guo, Xiao-Xi; An, Su; Yang, Yang; Liu, Ying; Hao, Qian; Xu, Tian-Rui

    2016-01-01

    Rap, a member of the Ras-like small G-protein family, is a key node among G-protein coupled receptors (GPCR), receptor tyrosine kinases (RTKs), ion channels and many other downstream pathways. Rap plays a unique role in cell morphogenesis, adhesion, migration, exocytosis, proliferation, apoptosis and carcinogenesis. The complexity and diversity of Rap functions are tightly regulated by Rap-interacting proteins such as GEFs, GAPs, Rap effectors and scaffold proteins. These interacting proteins decide the subcellular localization of Rap, the interaction modes with downstream Rap effectors and tune Rap as an atypical molecular conductor, coupling extra- and intracellular signals to various pathways. In this review, we summarize four groups of Rap-interacting proteins, highlight their distinctions in Rap-binding properties and interactive modes and discuss their contribution to the spatiotemporal regulation of Rap as well as the implications of targeting Rap-interacting proteins in human cancer therapy.

  12. Receptors of the thyroid: the thyrotropin receptor is only the first violinist of a symphony orchestra.

    PubMed

    Kohn, L D; Saji, M; Akamizu, T; Ikuyama, S; Isozaki, O; Kohn, A D; Santisteban, P; Chan, J Y; Bellur, S; Rotella, C M

    1989-01-01

    A basic reason for undertaking these studies was to further our knowledge of the structure and function of the TSH receptor as well as its interaction with other receptors on thyroid cells. The multiplicity of observations suggests the approach is bearing fruit, does not provide a simple answer, and can have pitfalls. We hope they may also contribute to understanding the structure and function of autoantigens in Graves' disease and glycoprotein hormone receptors in general. The authors are grateful to their collaborators in the National Dental Institute, particularly Drs. Bellur Prabhakar, Edward Oates, and Abner Notkins, in the National Cancer Institute, Drs. W. O. McBride and M. Lerman for their contributions to the cloning studies.

  13. From cacophony to symphony: how to focus the discipline of business continuity.

    PubMed

    Copenhaver, John; Lindstedt, David

    2010-03-01

    On the 'stage' of business continuity, there is a cacophony of voices--an unfocused assortment of ideas, approaches and advice. A casual glance at any continuity trade journal quickly reveals disparate discussions about even the most fundamental of issues. The dedicated magazines and conferences are filled with anecdotes and case studies but lack a focused discussion leading towards a holistic approach to the discipline. In fact, most often these discussions are not proper conversations at all, but disjointed groupings of loosely connected topics. It is time for practitioners to organise their considerable collective talent into a structured effort to ground and defend this growing profession. It is time to move from an informal sharing of individual lessons learned to a studied discipline. This paper proposes several ways to focus thinking and energise efforts. It will offer a select few topics to help provide a framework of central focal points for research, thought and growth.

  14. Resurrection Symphony: "El Sistema" as Ideology in Venezuela and Los Angeles

    ERIC Educational Resources Information Center

    Fink, Robert

    2016-01-01

    The explosive growth of Venezuela's "El Sistema" is rewriting the agenda of musical education in the West. Many commentators from the world of classical music react to the spectacle of dedicated young colonial musicians playing European masterworks as a kind of "miracle," accepting "Sistema" founder José Antonio…

  15. Toward a Symphony of Reactivity: Cascades Involving Catalysis and Sigmatropic Rearrangements

    PubMed Central

    Jones, Amanda C.; May, Jeremy A.; Sarpong, Richmond; Stoltz, Brian M.

    2014-01-01

    Catalysis and synthesis are intimately linked in modern organic chemistry. The synthesis of complex molecules is an ever evolving area of science. In many regards, the inherent beauty associated with a synthetic sequence can be linked to a certain combination of the creativity with which a sequence is designed and the overall efficiency with which the ultimate process is performed. In synthesis, as in other endeavors, beauty is very much in the eyes of the beholder.[**] It is with this in mind that we will attempt to review an area of synthesis that has fascinated us and that we find extraordinarily beautiful, namely the combination of catalysis and sigmatropic rearrangements in consecutive and cascade sequences. PMID:24677683

  16. It's a bittersweet symphony: simultaneously mixed emotional responses to music with conflicting cues.

    PubMed

    Larsen, Jeff T; Stastny, Bradley J

    2011-12-01

    Some evidence indicates that emotional reactions to music can be organized along a bipolar valence dimension ranging from pleasant states (e.g., happiness) to unpleasant states (e.g., sadness), but songs can contain some cues that elicit happiness (e.g., fast tempos) and others that elicit sadness (e.g., minor modes). Some models of emotion contend that valence is a basic building block of emotional experience, which implies that songs with conflicting cues cannot make people feel happy and sad at the same time. Other models contend that positivity and negativity are separable in experience, which implies that music with conflicting cues might elicit simultaneously mixed emotions of happiness and sadness. Hunter, Schellenberg, and Schimmack (2008) tested these possibilities by having subjects report their happiness and sadness after listening to music with conflicting cues (e.g., fast songs in minor modes) and consistent cues (e.g., fast songs in major modes). Results indicated that music with conflicting cues elicited mixed emotions, but it remains unclear whether subjects simultaneously felt happy and sad or merely vacillated between happiness and sadness. To examine these possibilities, we had subjects press one button whenever they felt happy and another button whenever they felt sad as they listened to songs with conflicting and consistent cues. Results revealed that subjects spent more time simultaneously pressing both buttons during songs with conflicting, as opposed to consistent, cues. These findings indicate that songs with conflicting cues can simultaneously elicit happiness and sadness and that positivity and negativity are separable in experience.

  17. Quorum-Sensing Kinetics in Saccharomyces cerevisiae: A Symphony of ARO Genes and Aromatic Alcohols.

    PubMed

    Avbelj, Martina; Zupan, Jure; Kranjc, Luka; Raspor, Peter

    2015-09-30

    The kinetics of quorum sensing in Saccharomyces cerevisiae were studied using a mini-fermentation platform. The quorum-sensing molecules were monitored using our previous HPLC approach that is here supported by quantitative real-time PCR analysis of the quorum-sensing genes. We thus initially confirm correlations between peak production rates of the monitored quorum-sensing molecules 2-phenylethanol, tryptophol, and tyrosol and peak expression of the genes responsible for their synthesis: ARO8, ARO9, and ARO10. This confirms the accuracy of our previously implemented kinetic model, thus favoring its use in further studies in this field. We also show that the quorum-sensing kinetics are precisely dependent on the population growth phase and that tyrosol production is also regulated by cell concentration, which has not been reported previously. Additionally, we show that during wine fermentation, ethanol stress reduces the production of 2-phenylethanol, tryptophol, and tyrosol, which opens new challenges in the control of wine fermentation.

  18. Flow, Sediment Transport, and Erosion in Steep Mountain Channels: an Alpine Symphony

    NASA Astrophysics Data System (ADS)

    Kirchner, J. W.; Beer, A. R.; Heimann, F.; Rickenmann, D.; Schneider, J. M.; von Boetticher, A.; Turowski, J. M.

    2015-12-01

    Steep headwater channels comprise a large fraction of the total channel length in mountainous regions. They control the transport of water, solutes, and sediments to larger rivers downstream, and regulate the erosional development of many mountain landscapes. Flow and transport processes in these steep channels contrast with those in their lower-gradient counterparts. Steep streams have complex bed morphology, with large roughness relative to the flow depth, and the flow is likewise complex, often comprising a variable mixture of air and water. Here we present several examples from Switzerland highlighting recent research into hydraulics, sediment transport, and bedrock erosion in steep Alpine channels. The Riedbach presents a striking natural experiment, in which the channel gradient steepens from roughly 3% to more than 40% in less than 1km, while the discharge, flow width, and sediment transport rates remain roughly constant. Measurements at the Riedbach illustrate the self-adjustment of flow velocity and bed roughness in steep mountain channels. Data from the Erlenbach, an intensively instrumented stream in the Alpine foothills, illustrate how the bed configuration of such streams regulates the relationship between flow and sediment transport. Field studies at the Gornera illustrate how flow patterns control the spatial distribution of bedrock erosion in this glacier-fed stream in the shadow of the Matterhorn. We present an overview of these studies and discuss their implications.

  19. Leveraging the trusted clinician: documenting disease management program enrollment.

    PubMed

    Frazee, Sharon Glave; Kirkpatrick, Patricia; Fabius, Raymond; Chimera, Joseph

    2007-02-01

    The objective of this study was to test the hypothesis that an integrated disease management (IDM) protocol (patent-pending), which combines telephonic-delivered disease management (TDM) with a worksite-based primary care center and pharmacy delivery, would yield higher contact and enrollment rates than traditional remote disease management alone. IDM is characterized by the combination of standard TDM with a worksite-based primary care and pharmacy delivery protocol led by trusted clinicians. This prospective cohort study tracks contact and enrollment rates for persons assigned to either IDM or traditional TDM protocols, and compares them on contact and enrollment efficiency. The IDM protocol showed a significant improvement in contact and enrollment rates over traditional TDM. Integrating a worksite-based primary care and pharmacy delivery system led by trusted clinicians with traditional TDM increases contact and enrollment rates, resulting in higher patient engagement. The IDM protocol should be adopted by employers seeking higher returns on their investment in disease management programming.

  20. Pilot scale processing of simulated Savannah River Site high level radioactive waste

    SciTech Connect

    Hutson, N.D.; Zamecnik, J.R.; Ritter, J.A.; Carter, J.T.

    1991-12-31

    The Savannah River Laboratory operates the Integrated DWPF Melter System (IDMS), which is a pilot-scale test facility used in support of the start-up and operation of the US Department of Energy`s Defense Waste Processing Facility (DWPF). Specifically, the IDMS is used in the evaluation of the DWPF melter and its associated feed preparation and offgass treatment systems. This article provides a general overview of some of the test work which has been conducted in the IDMS facility. The chemistry associated with the chemical treatment of the sludge (via formic acid adjustment) is discussed. Operating experiences with simulated sludge containing high levels of nitrite, mercury, and noble metals are summarized.

  1. Digital Solutions for Informed Decision Making: An Academic-Community Partnership for the Development of a Prostate Cancer Decision Aid for African-American Men

    PubMed Central

    Owens, Otis L.; Friedman, Daniela B.; Brandt, Heather M.; Bernhardt, Jay M.; Hébert, James R.

    2014-01-01

    African-American (AA) men are significantly more likely to die of prostate cancer (PrCA) than other racial groups, and there is a critical need to identify strategies for providing information about PrCA screening and the importance of informed decision making (IDM). To assess whether a computer-based IDM intervention for PrCA screening would be appropriate for AA men, this formative evaluation study examined their (1) PrCA risk and screening knowledge, (2) decision-making processes for PrCA screening, (3) usage of, attitudes toward, and access to interactive communication technologies (ICTs), and (4) perceptions regarding a future novel computer-based PrCA education intervention. A purposive convenience sample of 39 AA men aged 37–66 years in the Southeastern United States were recruited through faith-based organizations to participate in one of six 90-minute focus groups and complete a 45-item descriptive survey. Participants were generally knowledgeable about PrCA; however, few engaged in IDM with their doctor and few were informed about the associated risks and uncertainties of PrCA screening. Most participants used ICTs on a daily basis for various purposes including health information seeking. Most participants were open to a novel computer-based intervention if the system was easy to use and its animated avatars were culturally appropriate. Because study participants had low exposure to IDM for PrCA, but frequently used ICTs, IDM interventions using ICTs (e.g, computers) hold promise for AA men and should be explored for feasibility and effectiveness. These interventions should aim to increase PrCA screening knowledge and stress the importance of participating in IDM with their doctor. PMID:25563381

  2. Tank 241-AY-102 Leak Assessment Supporting Documentation: Miscellaneous Reports, Letters, Memoranda, And Data

    SciTech Connect

    Engeman, J. K.; Girardot, C. L.; Harlow, D. G.; Rosenkrance, C. L.

    2012-12-20

    This report contains reference materials cited in RPP-ASMT -53793, Tank 241-AY-102 Leak Assessment Report, that were obtained from the National Archives Federal Records Repository in Seattle, Washington, or from other sources including the Hanford Site's Integrated Data Management System database (IDMS).

  3. SYMPHONY, an information-theoretic method for gene–gene and gene–environment interaction analysis of disease syndromes

    PubMed Central

    Knights, J; Yang, J; Chanda, P; Zhang, A; Ramanathan, M

    2013-01-01

    We develop an information-theoretic method for gene–gene (GGI) and gene–environmental interactions (GEI) analysis of syndromes, defined as a phenotype vector comprising multiple quantitative traits (QTs). The K-way interaction information (KWII), an information-theoretic metric, was derived for multivariate normal distributed phenotype vectors. The utility of the method was challenged with three simulated data sets, the Genetic Association Workshop-15 (GAW15) rheumatoid arthritis data set, a high-density lipoprotein (HDL) and atherosclerosis data set from a mouse QT locus study, and the 1000 Genomes data. The dependence of the KWII on effect size, minor allele frequency, linkage disequilibrium, population stratification/admixture, as well as the power and computational time requirements of the novel method was systematically assessed in simulation studies. In these studies, phenotype vectors containing two and three constituent multivariate normally distributed QTs were used and the KWII was found to be effective at detecting GEI associated with the phenotype. High KWII values were observed for variables and variable combinations associated with the syndrome phenotype compared with uninformative variables not associated with the phenotype. The KWII values for the phenotype-associated combinations increased monotonically with increasing effect size values. The KWII also exhibited utility in simulations with non-linear dependence between the constituent QTs. Analysis of the HDL and atherosclerosis data set indicated that the simultaneous analysis of both phenotypes identified interactions not detected in the analysis of the individual traits. The information-theoretic approach may be useful for non-parametric analysis of GGI and GEI of complex syndromes. PMID:23423149

  4. Precise time and frequency intercomparison between NPL, India and PTB, Federal Republic of Germany via satellite symphonie-1

    NASA Technical Reports Server (NTRS)

    Mathur, B. S.; Banerjee, P.; Sood, P. C.; Saxena, M.; Kumar, N.; Suri, A. K.

    1981-01-01

    A time and frequency intercomparison experiment conducted using Earth stations in New Delhi, India and Raisting, FRG is described. The NPL clock was placed at New Delhi Earth Station and the Raisting Clock was calibrated with PTB/Primary standard via LORAN-C and travelling clocks. The random uncertainity of time comparisons, represented by two sample Allan Variance sigma (30 seconds), was less than 10 nanoseconds. The relative frequency difference between the NPL and Raisting Clocks, SNPL, RAIS, as measured over the 44 days period was found to be -15.7 x 10 to the -13th power. The relative frequency difference between PTB Primary Standard and Raisting Clock, SPTB, RAIS, during this period, was measured to be -22.8 x 10 to the -13th power. The relative frequency difference between NPL clock and PTB Primary Standard, SNPL, PTB, thus, is +7.1 x 10 to the -13th power. The clock rate (UTC, India) of +7.1 + or - 0.5 x 10 to the -13th power, agrees well with that obtained via VLF phase measurements over one year period and with USNO travelling clock time comparisons made in September, 1980.

  5. Leveraging the trusted clinician: increasing retention in disease management through integrated program delivery.

    PubMed

    Frazee, Sharon Glave; Sherman, Bruce; Fabius, Raymond; Ryan, Pamela; Kirkpatrick, Patricia; Davis, Jeffery

    2008-10-01

    Disease management's (DM's) value largely depends on achieving and maintaining participation. Simply being enrolled in a program does not guarantee engaged participation by enrollees, a necessary factor to achieve the improved health outcomes and subsequent reduced health care costs that are the ultimate objective of DM. The objective of this study is to test the hypothesis that an integrated disease management (IDM) protocol (patent-pending), which combines telephonic-delivered disease management (TDM) with a worksite-based primary care center and pharmacy delivery, yields higher patient retention rates than traditional remote DM alone. An earlier study of the IDM protocol found that integrating a worksite-based primary care and pharmacy delivery system with traditional telephonic-based DM substantially increased contact, enrollment, and engagement rates compared to traditional stand-alone telephonic DM. This prospective cohort study tracks contact and enrollment rates for persons assigned to either IDM or traditional TDM protocols and compares participation rates at 6- and 12-month intervals as well as measures of continued retention in the DM program. The IDM protocol showed a significant improvement in participation persistence over traditional TDM. Integrating a worksite-based primary care and pharmacy delivery system led by "trusted clinicians at the workplace"trade mark with traditional telephonic-based DM not only increases contact and enrollment rates, but also results in higher patient engagement and retention. These improvements in participation are expected to result in improved outcomes for a larger proportion of the target population than traditional telephonic DM.

  6. African American men, prostate cancer screening and informed decision making.

    PubMed Central

    Sellers, Denethia B.; Ross, Louie E.

    2003-01-01

    Prostate cancer is the second leading cause of cancer deaths in African American men. African Americans are at increased risk over other groups and have higher mortality. Since prostate cancer is highly variable among men, medical organizations are not in agreement whether men should be screened or the appropriate ages to screen. Many of these organizations recommend discussion with patients about the benefits and limitations of screening. Some of these groups support informed decision-making (IDM). Through IDM, the patient obtains all of the information about prostate cancer including risk, to make an informed choice regarding screening. Due to several factors including lowered engagement of African American men in the healthcare system, disparities in treatment, increased risk in developing and dying from the disease, as well as other cultural and structural constraints, IDM is examined and proposed as an appropriate tool for African American men. The use of IDM is discussed, along with several challenges and cautions. We conclude with recommendations and suggestions to the provider and patient to facilitate discussions regarding prostate cancer. PMID:12911259

  7. Immobilization of simulated high-level radioactive waste in borosilicate glass: Pilot scale demonstrations

    SciTech Connect

    Ritter, J.A.; Hutson, N.D.; Zamecnik, J.R.; Carter, J.T.

    1991-01-01

    The Integrated DWPF Melter System (IDMS), operated by the Savannah River Laboratory, is a pilot scale facility used in support of the start-up and operation of the Department of Energy's Defense Waste Processing Facility. The IDMS has successfully demonstrated, on an engineering scale (one-fifth), that simulated high level radioactive waste (HLW) sludge can be chemically treated with formic acid to adjust both its chemical and physical properties, and then blended with simulated precipitate hydrolysis aqueous (PHA) product and borosilicate glass frit to produce a melter feed which can be processed into a durable glass product. The simulated sludge, PHA and frit were blended, based on a product composition program, to optimize the loading of the waste glass as well as to minimize those components which can cause melter processing and/or glass durability problems. During all the IDMS demonstrations completed thus far, the melter feed and the resulting glass that has been produced met all the required specifications, which is very encouraging to future DWPF operations. The IDMS operations also demonstrated that the volatile components of the melter feed (e.g., mercury, nitrogen and carbon, and, to a lesser extent, chlorine, fluorine and sulfur) did not adversely affect the melter performance or the glass product.

  8. Immobilization of simulated high-level radioactive waste in borosilicate glass: Pilot scale demonstrations

    SciTech Connect

    Ritter, J.A.; Hutson, N.D.; Zamecnik, J.R.; Carter, J.T.

    1991-12-31

    The Integrated DWPF Melter System (IDMS), operated by the Savannah River Laboratory, is a pilot scale facility used in support of the start-up and operation of the Department of Energy`s Defense Waste Processing Facility. The IDMS has successfully demonstrated, on an engineering scale (one-fifth), that simulated high level radioactive waste (HLW) sludge can be chemically treated with formic acid to adjust both its chemical and physical properties, and then blended with simulated precipitate hydrolysis aqueous (PHA) product and borosilicate glass frit to produce a melter feed which can be processed into a durable glass product. The simulated sludge, PHA and frit were blended, based on a product composition program, to optimize the loading of the waste glass as well as to minimize those components which can cause melter processing and/or glass durability problems. During all the IDMS demonstrations completed thus far, the melter feed and the resulting glass that has been produced met all the required specifications, which is very encouraging to future DWPF operations. The IDMS operations also demonstrated that the volatile components of the melter feed (e.g., mercury, nitrogen and carbon, and, to a lesser extent, chlorine, fluorine and sulfur) did not adversely affect the melter performance or the glass product.

  9. Isotope dilution ICP-MS with laser-assisted sample introduction for direct determination of sulfur in petroleum products.

    PubMed

    Boulyga, Sergei F; Heilmann, Jens; Heumann, Klaus G

    2005-08-01

    Inductively coupled plasma isotope dilution mass spectrometry (ICP-IDMS) with direct laser-assisted introduction of isotope-diluted samples into the plasma, using a laser ablation system with high ablation rates, was developed for accurate sulfur determinations in different petroleum products such as 'sulfur-free' premium gasoline, diesel fuel, and heating oil. Two certified gas oil reference materials were analyzed for method validation. Two different 34S-enriched spike compounds, namely, elementary sulfur dissolved in xylene and dibenzothiophene in hexane, were synthesized and tested for their usefulness in this isotope dilution technique. The isotope-diluted sample was adsorbed on a filter-paper-like material, which was fixed in a special holder for irradiation by the laser beam. Under these conditions no time-dependent spike/analyte fractionation was only observed for the dibenzothiophene spike during the laser ablation process, which means that the measured 34S/32S isotope ratio of the isotope-diluted sample remained constant-a necessary precondition for accurate results with the isotope dilution technique. A comparison of LA-ICP-IDMS results with the certified values of the gas oil reference materials and with results obtained from ICP-IDMS analyses with wet sample digestion demonstrated the accuracy of the new LA-ICP-IDMS method in the concentration range of 9.2 microg g(-1) ('sulfur-free' premium gasoline) to 10.4 mg g(-1) (gas oil reference material BCR 107). The detection limit for sulfur by LA-ICP-IDMS is 0.04 microg g(-1) and the analysis time is only about 10 min, which therefore also qualifies this method for accurate determinations of low sulfur contents in petroleum products on a routine level.

  10. Solar system positioning system

    NASA Technical Reports Server (NTRS)

    Penanen, Konstantin I.; Chui, Talso

    2006-01-01

    Power-rich spacecraft envisioned in Prometheus initiative open up possibilities for long-range high-rate communication. A constellation of spacecraft on orbits several A.U. from the Sun, equipped with laser transponders and precise clocks can be configured to measure their mutual distances to within few cm. High on-board power can create substantial non-inertial contribution to the spacecraft trajectory. We propose to alleviate this contribution by employing secondary ranging to a passive daughter spacecraft. Such constellation can form the basis of it navigation system capable of providing position information anywhere in the soIar system with similar accuracy. Apart from obvious Solar System exploration implications, this system can provide robust reference for GPS and its successors.

  11. Hydrogen generation during treatment of simulated high-level radioactive waste with formic acid

    SciTech Connect

    Ritter, J.A.; Zamecnik, J.R.; Hsu, C.W.

    1992-01-01

    The Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS), operated by the Savannah River Laboratory, is a one-fifth scale pilot facility used in support of the start-up and operation of the Department of Energy's DWPF. Five IDMS runs determined the effect of the presence of noble metals in HLW sludge on the H{sub 2} generation rate during the preparation of melter feed with formic acid. Overall, the results clearly showed that H{sub 2} generation in the DWPF SRAT could, at times, exceed the lower flammable limit of H{sub 2} in air (4 vol%), depending on such factors as offgas generation and air inleakage of the DWPF vessels. Therefore, the installation of a forced air purge system and H{sub 2} monitors were recommended to the DWPF to control the generation of H{sub 2} during melter feed preparation by fuel dilution.

  12. Hydrogen generation during treatment of simulated high-level radioactive waste with formic acid

    SciTech Connect

    Ritter, J.A.; Zamecnik, J.R.; Hsu, C.W.

    1992-05-01

    The Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS), operated by the Savannah River Laboratory, is a one-fifth scale pilot facility used in support of the start-up and operation of the Department of Energy`s DWPF. Five IDMS runs determined the effect of the presence of noble metals in HLW sludge on the H{sub 2} generation rate during the preparation of melter feed with formic acid. Overall, the results clearly showed that H{sub 2} generation in the DWPF SRAT could, at times, exceed the lower flammable limit of H{sub 2} in air (4 vol%), depending on such factors as offgas generation and air inleakage of the DWPF vessels. Therefore, the installation of a forced air purge system and H{sub 2} monitors were recommended to the DWPF to control the generation of H{sub 2} during melter feed preparation by fuel dilution.

  13. Bifurcation Phenomena of Opinion Dynamics in Complex Networks

    NASA Astrophysics Data System (ADS)

    Guo, Long; Cai, Xu

    In this paper, we study the opinion dynamics of Improved Deffuant model (IDM), where the convergence parameter μ is a function of the opposite’s degree K according to the celebrity effect, in small-world network (SWN) and scale-free network (SFN). Generically, the system undergoes a phase transition from the plurality state to the polarization state and to the consensus state as the confidence parameter ɛ increasing. Furthermore, the evolution of the steady opinion s * as a function of ɛ, and the relation between the minority steady opinion s_{*}^{min} and the individual connectivity k also have been analyzed. Our present work shows the crucial role of the confidence parameter and the complex system topology in the opinion dynamics of IDM.

  14. Determination of tributyltin (TBT) in marine sediment using pressurised liquid extraction-gas chromatography-isotope dilution mass spectrometry (PLE-GC-IDMS) with a hexane-tropolone mixture.

    PubMed

    Konieczka, Piotr; Sejerøe-Olsen, Berit; Linsinger, Thomas P J; Schimmel, Heinz

    2007-06-01

    Extraction conditions for the determination of tributyltin (TBT) in sediment samples have been developed further. The analytical procedure is based on spiking with isotopically labelled analyte, pressurised liquid extraction (PLE) with a hexane/tropolone mixture, Grignard derivatization and quantification by GC-MS. It was applied to two unknown sediment samples as part of an intercomparison exercise of the Comité Consultatif pour la Quantité de Matière (CCQM). The detection limit was approximately 1.5 ng/g TBT as Sn, while the repeatability and intermediate precision (as the coefficient of variation) were 1.9% and 3.2%, respectively. The expanded uncertainty was 6.2% (coverage factor k = 2), and the accuracy was confirmed by measurement of a certified reference material.

  15. Immune System

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Immune System KidsHealth > For Teens > Immune System A A A ... could put us out of commission. What the Immune System Does The immune (pronounced: ih-MYOON) system, which ...

  16. Data Systems vs. Information Systems

    PubMed Central

    Amatayakul, Margret K.

    1982-01-01

    This paper examines the current status of “hospital information systems” with respect to the distinction between data systems and information systems. It is proposed that the systems currently existing are incomplete data dystems resulting in ineffective information systems.

  17. Operating Systems.

    ERIC Educational Resources Information Center

    Denning, Peter J.; Brown, Robert L.

    1984-01-01

    A computer operating system spans multiple layers of complexity, from commands entered at a keyboard to the details of electronic switching. In addition, the system is organized as a hierarchy of abstractions. Various parts of such a system and system dynamics (using the Unix operating system as an example) are described. (JN)

  18. Benefits of Continuing Professional Development (CPD) Programmes in Music for KS2 (Primary) Teachers through the Example of the London Symphony Orchestra (LSO) on Track Programme

    ERIC Educational Resources Information Center

    Varvarigou, Maria; Creech, Andrea; Hallam, Susan

    2012-01-01

    Between September 2008 and August 2010 24 KS2 classroom teachers were involved in a two-year programme of continuing professional development (CPD), delivered by the LSO in partnership with Local Authority Music Services. The teachers indicated that they embarked on the CPD programme looking forward to opportunities to share good practice, gain…

  19. Neural rhythmic symphony of human walking observation: Upside-down and Uncoordinated condition on cortical theta, alpha, beta and gamma oscillations

    PubMed Central

    Zarka, David; Cevallos, Carlos; Petieau, Mathieu; Hoellinger, Thomas; Dan, Bernard; Cheron, Guy

    2014-01-01

    Biological motion observation has been recognized to produce dynamic change in sensorimotor activation according to the observed kinematics. Physical plausibility of the spatial-kinematic relationship of human movement may play a major role in the top-down processing of human motion recognition. Here, we investigated the time course of scalp activation during observation of human gait in order to extract and use it on future integrated brain-computer interface using virtual reality (VR). We analyzed event related potentials (ERP), the event related spectral perturbation (ERSP) and the inter-trial coherence (ITC) from high-density EEG recording during video display onset (−200–600 ms) and the steady state visual evoked potentials (SSVEP) inside the video of human walking 3D-animation in three conditions: Normal; Upside-down (inverted images); and Uncoordinated (pseudo-randomly mixed images). We found that early visual evoked response P120 was decreased in Upside-down condition. The N170 and P300b amplitudes were decreased in Uncoordinated condition. In Upside-down and Uncoordinated conditions, we found decreased alpha power and theta phase-locking. As regards gamma oscillation, power was increased during the Upside-down animation and decreased during the Uncoordinated animation. An SSVEP-like response oscillating at about 10 Hz was also described showing that the oscillating pattern is enhanced 300 ms after the heel strike event only in the Normal but not in the Upside-down condition. Our results are consistent with most of previous point-light display studies, further supporting possible use of virtual reality for neurofeedback applications. PMID:25278847

  20. Two-Way Time Transfer via Geostationary Satellites NRC/NBS, NRC/USNO and NBS/USNO via Hermes and NRC/LPTF (France) via Symphonie

    NASA Technical Reports Server (NTRS)

    Costain, C.; Boulanger, J. S.; Daams, H.; Hanson, D. W.; Beehler, R. E.; Clements, A. J.; Davis, D. D.; Klepczynski, W. J.; Veenstra, L. B.; Kaiser, J.

    1979-01-01

    In most of the experiments, 1 pps pulses of the station atomic clocks were exchanged between the partners, and a cubic equation was fitted to the 1000 to 2000 second measurements. The equations were exchanged and substracted to obtain the time difference of the stations. The standard deviation in the fit of the equations varied, depending on conditions, from 1.5 ns to 16 ns. For the last month of the Hermes experiment, a 1 MHz signal was used, giving a standard deviation of 0.18 ns. The comparison of the time scales via satellite and via Loran-C (BIH Circular D) show clearly that some Loran-C links are very good, but that the NBS link varies by 1 micron s. Via the satellite the frequencies of the time scales can be compared with an accuracy of 2 x 10 to the minus 14 power.

  1. Respiratory System

    MedlinePlus

    ... this page from the NHLBI on Twitter. The Respiratory System The respiratory system is made up of organs ... vessels, and the muscles that enable breathing. The Respiratory System Figure A shows the location of the respiratory ...

  2. Lymph system

    MedlinePlus

    Lymphatic system ... Dains JE, Flynn JA, Solomon BS, Stewart RW. Lymphatic system. In: Ball JW, Dains JE, Flynn JA, Solomon ... 2015:chap 9. Hall JE. The microcirculation and lymphatic system: capillary fluid exchange, interstitial fluid, and lymph flow. ...

  3. Digestive System

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Digestive System KidsHealth > For Parents > Digestive System A A A ... the body can absorb and use. About the Digestive System Almost all animals have a tube-type digestive ...

  4. Isotope dilution mass spectrometry for quantitative elemental analysis of powdered samples by radiofrequency pulsed glow discharge time of flight mass spectrometry.

    PubMed

    Alvarez-Toral, Aitor; Fernandez, Beatriz; Malherbe, Julien; Claverie, Fanny; Molloy, John L; Pereiro, Rosario; Sanz-Medel, Alfredo

    2013-10-15

    In recent years particular effort is being devoted to the development of pulsed glow discharges (PGDs) for mass spectrometry because this powering operation mode could offer important ionization analytical advantages. However, the capabilities of radiofrequency (RF) PGD coupled to a time of flight mass spectrometry (ToFMS) for accurate isotope ratio measurements have not been demonstrated yet. This work is focused on investigating different time positions along the pulse profile for the accurate measurement of isotope ratios. As a result, a method has been developed for the direct and simultaneous multielement determination of trace elements in powdered geological samples by RF-PGD-ToFMS in combination with isotope dilution mass spectrometry (IDMS) as an absolute measurement method directly traceable to the International System of Units. Optimized operating conditions were 70 W of applied radiofrequency power, 250 Pa of pressure, 2 ms of pulse width and 4 ms of pulse period, being argon the plasma gas used. To homogeneously distribute the added isotopically-enriched standards, lithium borate fusion of powdered solid samples was used as sample preparation approach. In this way, Cu, Zn, Ba and Pb were successfully determined by RF-PGD-ToF(IDMS) in two NIST Standard Reference Materials (SRM 2586 and SRM 2780) representing two different matrices of geological interest (soil and rock samples). Cu, Zn, Ba and Pb concentrations determined by RF-PGD-ToF(IDMS) were well in agreement with the certified values at 95% confidence interval and precisions below 12% relative standard deviation were observed for three independent analyses. Elemental concentrations investigated were in the range of 81-5770 mg/kg, demonstrating the potential of RF-PGD-ToF(IDMS) for a sensitive, accurate and robust analysis of powdered samples.

  5. Mechanical Systems

    NASA Technical Reports Server (NTRS)

    Davis, Robert E.

    2002-01-01

    The presentation provides an overview of requirement and interpretation letters, mechanical systems safety interpretation letter, design and verification provisions, and mechanical systems verification plan.

  6. Systems Thinking (and Systems Doing).

    ERIC Educational Resources Information Center

    Brethower, Dale M.; Dams, Peter-Cornelius

    1999-01-01

    Introduces human performance technology (HPT) by answering the following questions related to: what systems does; practical issues and questions to which systems thinking is relevant; research questions and answers with respect to systems thinking; how HPT practitioners can do systems thinking; systems thinking tools; what is and is not known…

  7. Fluid Management System (FMS) fluid systems overview

    NASA Technical Reports Server (NTRS)

    Baird, R. S.

    1990-01-01

    Viewgraphs on fluid management system (FMS) fluid systems overview are presented. Topics addressed include: fluid management system description including system requirements (integrated nitrogen system, integrated water system, and integrated waste gas system) and physical description; and fluid management system evolution.

  8. Systems thinking.

    PubMed

    Cabrera, Derek; Colosi, Laura; Lobdell, Claire

    2008-08-01

    Evaluation is one of many fields where "systems thinking" is popular and is said to hold great promise. However, there is disagreement about what constitutes systems thinking. Its meaning is ambiguous, and systems scholars have made diverse and divergent attempts to describe it. Alternative origins include: von Bertalanffy, Aristotle, Lao Tsu or multiple aperiodic "waves." Some scholars describe it as synonymous with systems sciences (i.e., nonlinear dynamics, complexity, chaos). Others view it as taxonomy-a laundry list of systems approaches. Within so much noise, it is often difficult for evaluators to find the systems thinking signal. Recent work in systems thinking describes it as an emergent property of four simple conceptual patterns (rules). For an evaluator to become a "systems thinker", he or she need not spend years learning many methods or nonlinear sciences. Instead, with some practice, one can learn to apply these four simple rules to existing evaluation knowledge with transformative results.

  9. Telemetry Systems

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Goddard Space Flight Center developed satellite telemetry processing technology to meet NASA's sophisticated processing requirements. The Microelectronic Systems Branch, a 'company' within Goddard, provided NASA with the telemetry data systems from 1985 to 1994. TSI/Telsys, Inc. was then founded to commercialize the systems and began operations on October 1, 1995. The system aids the remote sensing industry by providing affordable and quick access to data collected from space.

  10. Systems Engineering

    NASA Technical Reports Server (NTRS)

    Pellerano, Fernando

    2015-01-01

    This short course provides information on what systems engineering is and how the systems engineer guides requirements, interfaces with the discipline leads, and resolves technical issues. There are many system-wide issues that either impact or are impacted by the thermal subsystem. This course will introduce these issues and illustrate them with real life examples.

  11. System Effectiveness

    SciTech Connect

    Powell, Danny H; Elwood Jr, Robert H

    2011-01-01

    An effective risk assessment system is needed to address the threat posed by an active or passive insider who, acting alone or in collusion, could attempt diversion or theft of nuclear material. It is critical that a nuclear facility conduct a thorough self-assessment of the material protection, control, and accountability (MPC&A) system to evaluate system effectiveness. Self-assessment involves vulnerability analysis and performance testing of the MPC&A system. The process should lead to confirmation that mitigating features of the system effectively minimize the threat, or it could lead to the conclusion that system improvements or upgrades are necessary to achieve acceptable protection against the threat. Analysis of the MPC&A system is necessary to understand the limits and vulnerabilities of the system to internal threats. Self-assessment helps the facility be prepared to respond to internal threats and reduce the risk of theft or diversion of nuclear material. MSET is a self-assessment or inspection tool utilizing probabilistic risk assessment (PRA) methodology to calculate the system effectiveness of a nuclear facility's MPC&A system. MSET analyzes the effectiveness of an MPC&A system based on defined performance metrics for MPC&A functions based on U.S. and international best practices and regulations. A facility's MC&A system can be evaluated at a point in time and reevaluated after upgrades are implemented or after other system changes occur. The total system or specific subareas within the system can be evaluated. Areas of potential performance improvement or system upgrade can be assessed to determine where the most beneficial and cost-effective improvements should be made. Analyses of risk importance factors show that sustainability is essential for optimal performance. The analyses reveal where performance degradation has the greatest detrimental impact on total system risk and where performance improvements have the greatest reduction in system risk

  12. Cryogenic Systems

    NASA Astrophysics Data System (ADS)

    Hosoyama, Kenji

    2002-02-01

    In this lecture we discuss the principle of method of cooling to a very low temperature, i.e. cryogenic. The "gas molecular model" will be introduced to explain the mechanism cooling by the expansion engine and the Joule-Thomson expansion valve. These two expansion processes are normally used in helium refrigeration systems to cool the process gas to cryogenic temperature. The reverse Carnot cycle will be discussed in detail as an ideal refrigeration cycle. First the fundamental process of liquefaction and refrigeration cycles will be discussed, and then the practical helium refrigeration system. The process flow of the system and the key components; -compressor, expander, and heat exchanger- will be discussed. As an example of an actual refrigeration system, we will use the cryogenic system for the KEKB superconducting RF cavity. We will also discuss the liquid helium distribution system, which is very important, especially for the cryogenic systems used in accelerator applications. 1 Principles of Cooling and Fundamental Cooling Cycle 2 Expansion engine, Joule-Thomson expansion, kinetic molecular theory, and enthalpy 3 Liquefaction Systems 4 Refrigeration Systems 5 Practical helium liquefier/refrigeration system 6 Cryogenic System for TRISTAN Superconducting RF Cavity

  13. Geothermal systems

    NASA Technical Reports Server (NTRS)

    Mohl, C.

    1978-01-01

    Several tasks of JPL related to geothermal energy are discussed. The major task is the procurement and test and evaluation of a helical screw drive (wellhead unit). A general review of geothermal energy systems is given. The presentation focuses attention on geothermal reservoirs in California, with graphs and charts to support the discussion. Included are discussions on cost analysis, systems maintenance, and a comparison of geothermal and conventional heating and cooling systems.

  14. CALUTRON SYSTEM

    DOEpatents

    Lawrence, E.O.

    1958-08-12

    A calutron system capable of functioning with only a portion of the separation tanks in the system operating is described. The invention is a calutron system comprssing a closed series of alternated tanks and electromagnets having a mid-yoke connecting intermediate positions of the series. dividing the series into twv-o portions, and thereby providing a closed magnetic path through either of the portions.

  15. Systemic Darwinism

    PubMed Central

    Winther, Rasmus Grønfeldt

    2008-01-01

    Darwin's 19th century evolutionary theory of descent with modification through natural selection opened up a multidimensional and integrative conceptual space for biology. We explore three dimensions of this space: explanatory pattern, levels of selection, and degree of difference among units of the same type. Each dimension is defined by a respective pair of poles: law and narrative explanation, organismic and hierarchical selection, and variational and essentialist thinking. As a consequence of conceptual debates in the 20th century biological sciences, the poles of each pair came to be seen as mutually exclusive opposites. A significant amount of 21st century research focuses on systems (e.g., genomic, cellular, organismic, and ecological/global). Systemic Darwinism is emerging in this context. It follows a “compositional paradigm” according to which complex systems and their hierarchical networks of parts are the focus of biological investigation. Through the investigation of systems, Systemic Darwinism promises to reintegrate each dimension of Darwin's original logical space. Moreover, this ideally and potentially unified theory of biological ontology coordinates and integrates a plurality of mathematical biological theories (e.g., self-organization/structure, cladistics/history, and evolutionary genetics/function). Integrative Systemic Darwinism requires communal articulation from a plurality of perspectives. Although it is more general than these, it draws on previous advances in Systems Theory, Systems Biology, and Hierarchy Theory. Systemic Darwinism would greatly further bioengineering research and would provide a significantly deeper and more critical understanding of biological reality. PMID:18697926

  16. Systemic darwinism.

    PubMed

    Winther, Rasmus Grønfeldt

    2008-08-19

    Darwin's 19th century evolutionary theory of descent with modification through natural selection opened up a multidimensional and integrative conceptual space for biology. We explore three dimensions of this space: explanatory pattern, levels of selection, and degree of difference among units of the same type. Each dimension is defined by a respective pair of poles: law and narrative explanation, organismic and hierarchical selection, and variational and essentialist thinking. As a consequence of conceptual debates in the 20th century biological sciences, the poles of each pair came to be seen as mutually exclusive opposites. A significant amount of 21st century research focuses on systems (e.g., genomic, cellular, organismic, and ecological/global). Systemic Darwinism is emerging in this context. It follows a "compositional paradigm" according to which complex systems and their hierarchical networks of parts are the focus of biological investigation. Through the investigation of systems, Systemic Darwinism promises to reintegrate each dimension of Darwin's original logical space. Moreover, this ideally and potentially unified theory of biological ontology coordinates and integrates a plurality of mathematical biological theories (e.g., self-organization/structure, cladistics/history, and evolutionary genetics/function). Integrative Systemic Darwinism requires communal articulation from a plurality of perspectives. Although it is more general than these, it draws on previous advances in Systems Theory, Systems Biology, and Hierarchy Theory. Systemic Darwinism would greatly further bioengineering research and would provide a significantly deeper and more critical understanding of biological reality.

  17. Anticipatory systems as linguistic systems

    NASA Astrophysics Data System (ADS)

    Ekdahl, Bertil

    2000-05-01

    The idea of system is well established although not well defined. What makes up a system depends on the observer. Thinking in terms of systems is only a convenient way to conceptualize organizations, natural or artificial, that show coherent properties. Among all properties, which can be ascribed to systems, one property seems to be more outstanding than others, namely that of being anticipatory. In nature, anticipatory properties are found only in living organizations. In this way it can be said to separate non-living systems from living because there is no indication that any natural phenomenon occurring in systems where there is no indication of life is anticipatory. The characteristic of living systems is that they are exposed to the evolution contrary to causal systems that do not undergo changes due to the influence of the environment. Causal systems are related to the past in such a way that subsequent situations can be calculated from knowledge of past situations. In causal systems the past is the cause of the present and there is no reference to the future as a determining agent, contrary to anticipatory systems where expectations are the cause of the present action. Since anticipatory properties are characteristic of living systems, this property, as all other properties in living systems, is a result of the evolution and can be found in plants as well as in animals. Thus, it is not only tied to consciousness but is found at a more basic level, i.e., in the interplay between genotype and phenotype. Anticipation is part of the genetic language in such a way that appropriate actions, for events in the anticipatory systems environment, are inscribed in the genes. Anticipatory behavior, as a result of the interpretation of the genetic language, has been selected by the evolution. In this paper anticipatory systems are regarded as linguistic systems and I argue that as such anticipation cannot be fragmented but must be holistically studied. This has the

  18. Power system

    DOEpatents

    Hickam, Christopher Dale

    2008-03-18

    A power system includes a prime mover, a transmission, and a fluid coupler having a selectively engageable lockup clutch. The fluid coupler may be drivingly connected between the prime mover and the transmission. Additionally, the power system may include a motor/generator drivingly connected to at least one of the prime mover and the transmission. The power-system may also include power-system controls configured to execute a control method. The control method may include selecting one of a plurality of modes of operation of the power system. Additionally, the control method may include controlling the operating state of the lockup clutch dependent upon the mode of operation selected. The control method may also include controlling the operating state of the motor/generator dependent upon the mode of operation selected.

  19. Phacoemulsification systems.

    PubMed

    1989-11-01

    Our objectives in conducting this evaluation were to present an overview of a basic phacoemulsification system and its components, to describe the phacoemulsification procedure within the context of the operating principles of the system's components, and to compare two manufacturers' products. Specifications for additional phacoemulsification systems are available in the November 1989 edition of ECRI's Hospital Product Comparison System. Both of the evaluated systems enable a surgeon to perform a complete cataract extraction procedure by phacoemulsification. We rated both units Acceptable. In selecting a unit, users should consider performance, safety, human factors design, and manufacturer training and support. Although list prices vary widely among available systems, cost factors should not override clinical performance and safety requirements. While we measured certain engineering parameters, such as stroke length and ultrasound (US) output forces exerted on a medium, we stress that the results of these tests do not provide enough information to predict clinical performance. Clinical performance of phacoemulsification systems can be determined only by the experience of the clinicians who use them. Clinicians should review our evaluation thoroughly before making a purchasing decision. The information we present is useful for purchasing the evaluated or other available models because our criteria will guide users in assessing all components, and our findings and discussion on some aspects are common to many available systems (e.g., type of pump, irrigation and aspiration [I/A] characteristics). The in-depth clinical and technical information will help users to better understand principles, thereby helping them to better define their needs. Although we discovered a number of problems with the evaluated models, users should not assume that similar or other problems do not exist with systems that we did not evaluate. The willingness of manufacturers to cooperate in

  20. Electronic system

    DOEpatents

    Robison, G H; Dickson, J F

    1960-11-15

    An electronic system is designed for indicating the occurrence of a plurality of electrically detectable events within predetermined time intervals. The system comprises separate input means electrically associated with the events under observation an electronic channel associated with each input means, including control means and indicating means; timing means adapted to apply a signal from the input means after a predetermined time to the control means to deactivate each of the channels; and means for resetting the system to its initial condition after the observation of each group of events. (D.L.C.)

  1. Systems and Components Fuel Delivery System, Water Delivery System, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Systems and Components - Fuel Delivery System, Water Delivery System, Derrick Crane System, and Crane System Details - Marshall Space Flight Center, F-1 Engine Static Test Stand, On Route 565 between Huntsville and Decatur, Huntsville, Madison County, AL

  2. Systems Vaccinology

    PubMed Central

    Pulendran, Bali; Li, Shuzhao; Nakaya, Helder I

    2010-01-01

    Vaccination is one of the greatest triumphs of modern medicine, yet we remain largely ignorant of the mechanisms by which successful vaccines stimulate protective immunity. Two recent advances are beginning to illuminate such mechanisms: realization of the pivotal role of the innate immune system in sensing microbes and stimulating adaptive immunity, and advances in systems biology. Recent studies have used systems biology approaches to obtain a global picture of the immune responses to vaccination in humans. This has enabled the identification of early innate signatures that predict the immunogenicity of vaccines, and identification of potentially novel mechanisms of immune regulation. Here we review these advances, and critically examine the potential opportunities and challenges posed by systems biology in vaccine development. PMID:21029962

  3. Respiratory system

    NASA Technical Reports Server (NTRS)

    Bartlett, R. G., Jr.

    1973-01-01

    The general anatomy and function of the human respiratory system is summarized. Breathing movements, control of breathing, lung volumes and capacities, mechanical relations, and factors relevant to respiratory support and equipment design are discussed.

  4. Bioculture System

    NASA Technical Reports Server (NTRS)

    Figliozzi, Gianine; Sato, Kevin Y.; Sun. Sidney

    2013-01-01

    The document is a 2 page fact sheet that describes the Bioculture system, how it may be used by researchers for life science research, how and when it will be installed and validated aboard the international space station.

  5. Microelectromechanical Systems

    NASA Technical Reports Server (NTRS)

    Gabriel, Kaigham J.

    1995-01-01

    Micro-electromechanical systems (MEMS) is an enabling technology that merges computation and communication with sensing and actuation to change the way people and machines interact with the physical world. MEMS is a manufacturing technology that will impact widespread applications including: miniature inertial measurement measurement units for competent munitions and personal navigation; distributed unattended sensors; mass data storage devices; miniature analytical instruments; embedded pressure sensors; non-invasive biomedical sensors; fiber-optics components and networks; distributed aerodynamic control; and on-demand structural strength. The long term goal of ARPA's MEMS program is to merge information processing with sensing and actuation to realize new systems and strategies for both perceiving and controlling systems, processes, and the environment. The MEMS program has three major thrusts: advanced devices and processes, system design, and infrastructure.

  6. SAMPLING SYSTEM

    DOEpatents

    Hannaford, B.A.; Rosenberg, R.; Segaser, C.L.; Terry, C.L.

    1961-01-17

    An apparatus is given for the batch sampling of radioactive liquids such as slurries from a system by remote control, while providing shielding for protection of operating personnel from the harmful effects of radiation.

  7. Systems Studies

    SciTech Connect

    Graham, R.L.

    1998-03-17

    The Systems Studies Activity had two objectives: (1) to investigate nontechnical barriers to the deployment of biomass production and supply systems and (2) to enhance and extend existing systems models of bioenergy supply and use. For the first objective, the Activity focused on existing bioenergy markets. Four projects were undertaken: a comparative analysis of bioenergy in Sweden and Austria; a one-day workshop on nontechnical barriers jointly supported by the Production Systems Activity; the development and testing of a framework for analyzing barriers and drivers to bioenergy markets; and surveys of wood pellet users in Sweden, Austria and the US. For the second objective, two projects were undertaken. First, the Activity worked with the Integrated BioEnergy Systems (TBS) Activity of TEA Bioenergy Task XIII to enhance the BioEnergy Assessment Model (BEAM). This model is documented in the final report of the IBS Activity. The Systems Studies Activity contributed to enhancing the feedstock portion of the model by developing a coherent set of willow, poplar, and switchgrass production modules relevant to both the US and the UK. The Activity also developed a pretreatment module for switchgrass. Second, the Activity sponsored a three-day workshop on modeling bioenergy systems with the objectives of providing an overview of the types of models used to evaluate bioenergy and promoting communication among bioenergy modelers. There were nine guest speakers addressing different types of models used to evaluate different aspects of bioenergy, ranging from technoeconomic models based on the ASPEN software to linear programming models to develop feedstock supply curves for the US. The papers from this workshop have been submitted to Biomass and Bioenergy and are under editorial review.

  8. Systemic fluoride.

    PubMed

    Sampaio, Fábio Correia; Levy, Steven Marc

    2011-01-01

    There is substantial evidence that fluoride, through different applications and formulas, works to control caries development. The first observations of fluoride's effects on dental caries were linked to fluoride naturally present in the drinking water, and then from controlled water fluoridation programs. Other systemic methods to deliver fluoride were later suggested, including dietary fluoride supplements such as salt and milk. These systemic methods are now being questioned due to the fact that many studies have indicated that fluoride's action relies mainly on its post-eruptive effect from topical contact with the tooth structure. It is known that even the methods of delivering fluoride known as 'systemic' act mainly through a topical effect when they are in contact with the teeth. The effectiveness of water fluoridation in many geographic areas is lower than in previous eras due to the widespread use of other fluoride modalities. Nevertheless, this evidence should not be interpreted as an indication that systemic methods are no longer relevant ways to deliver fluoride on an individual basis or for collective health programs. Caution must be taken to avoid excess ingestion of fluoride when prescribing dietary fluoride supplements for children in order to minimize the risk of dental fluorosis, particularly if there are other relevant sources of fluoride intake - such as drinking water, salt or milk and/or dentifrice. Safe and effective doses of fluoride can be achieved when combining topical and systemic methods.

  9. Systemic trauma.

    PubMed

    Goldsmith, Rachel E; Martin, Christina Gamache; Smith, Carly Parnitzke

    2014-01-01

    Substantial theoretical, empirical, and clinical work examines trauma as it relates to individual victims and perpetrators. As trauma professionals, it is necessary to acknowledge facets of institutions, cultures, and communities that contribute to trauma and subsequent outcomes. Systemic trauma-contextual features of environments and institutions that give rise to trauma, maintain it, and impact posttraumatic responses-provides a framework for considering the full range of traumatic phenomena. The current issue of the Journal of Trauma & Dissociation is composed of articles that incorporate systemic approaches to trauma. This perspective extends conceptualizations of trauma to consider the influence of environments such as schools and universities, churches and other religious institutions, the military, workplace settings, hospitals, jails, and prisons; agencies and systems such as police, foster care, immigration, federal assistance, disaster management, and the media; conflicts involving war, torture, terrorism, and refugees; dynamics of racism, sexism, discrimination, bullying, and homophobia; and issues pertaining to conceptualizations, measurement, methodology, teaching, and intervention. Although it may be challenging to expand psychological and psychiatric paradigms of trauma, a systemic trauma perspective is necessary on both scientific and ethical grounds. Furthermore, a systemic trauma perspective reflects current approaches in the fields of global health, nursing, social work, and human rights. Empirical investigations and intervention science informed by this paradigm have the potential to advance scientific inquiry, lower the incidence of a broader range of traumatic experiences, and help to alleviate personal and societal suffering.

  10. Turbine system

    DOEpatents

    McMahan, Kevin Weston; Dillard, Daniel Jackson

    2016-05-03

    A turbine system is disclosed. The turbine system includes a transition duct having an inlet, an outlet, and a passage extending between the inlet and the outlet and defining a longitudinal axis, a radial axis, and a tangential axis. The outlet of the transition duct is offset from the inlet along the longitudinal axis and the tangential axis. The turbine system further includes a turbine section connected to the transition duct. The turbine section includes a plurality of shroud blocks at least partially defining a hot gas path, a plurality of buckets at least partially disposed in the hot gas path, and a plurality of nozzles at least partially disposed in the hot gas path. At least one of a shroud block, a bucket, or a nozzle includes means for withstanding high temperatures.

  11. Robotic System

    NASA Technical Reports Server (NTRS)

    1984-01-01

    A complicated design project, successfully carried out by New York manufacturing consultant with help from NERAC, Inc., resulted in new type robotic system being marketed for industrial use. Consultant Robert Price, operating at E.S.I, Inc. in Albany, NY, sought help from NERAC to develop an automated tool for deburring the inside of 8 inch breech ring assemblies for howitzers produced by Watervliet Arsenal. NERAC conducted a search of the NASA data base and six others. From information supplied, Price designed a system consisting of a standard industrial robot arm, with a specially engineered six-axis deburring tool fitted to it. A microcomputer and computer program direct the tool on its path through the breech ring. E.S.I. markets the system to aerospace and metal cutting industries for deburring, drilling, routing and refining machined parts.

  12. Microbiology System

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Technology originating in a NASA-sponsored study of the measurement of microbial growth in zero gravity led to the development of Biomerieux Vitek, Inc.'s VITEK system. VITEK provides a physician with accurate diagnostic information and identifies the most effective medication. Test cards are employed to identify organisms and determine susceptibility to antibiotics. A photo-optical scanner scans the card and monitors changes in the growth of cells contained within the card. There are two configurations - VITEK and VITEK JR as well as VIDAS, a companion system that detects bacteria, viruses, etc. from patient specimens. The company was originally created by McDonnell Douglas, the NASA contractor.

  13. ELECTRONIC SYSTEM

    DOEpatents

    Robison, G.H. et al.

    1960-11-15

    An electronic system is described for indicating the occurrence of a plurality of electrically detectable events within predetermined time intervals. It is comprised of separate input means electrically associated with the events under observation: an electronic channel associated with each input means including control means and indicating means; timing means associated with each of the input means and the control means and adapted to derive a signal from the input means and apply it after a predetermined time to the control means to effect deactivation of each of the channels; and means for resetting the system to its initial condition after observation of each group of events.

  14. Computer systems

    NASA Technical Reports Server (NTRS)

    Olsen, Lola

    1992-01-01

    In addition to the discussions, Ocean Climate Data Workshop hosts gave participants an opportunity to hear about, see, and test for themselves some of the latest computer tools now available for those studying climate change and the oceans. Six speakers described computer systems and their functions. The introductory talks were followed by demonstrations to small groups of participants and some opportunities for participants to get hands-on experience. After this familiarization period, attendees were invited to return during the course of the Workshop and have one-on-one discussions and further hands-on experience with these systems. Brief summaries or abstracts of introductory presentations are addressed.

  15. Complex Systems

    PubMed Central

    Goldberger, Ary L.

    2006-01-01

    Physiologic systems in health and disease display an extraordinary range of temporal behaviors and structural patterns that defy understanding based on linear constructs, reductionist strategies, and classical homeostasis. Application of concepts and computational tools derived from the contemporary study of complex systems, including nonlinear dynamics, fractals and “chaos theory,” is having an increasing impact on biology and medicine. This presentation provides a brief overview of an emerging area of biomedical research, including recent applications to cardiopulmonary medicine and chronic obstructive lung disease. PMID:16921107

  16. International Systems.

    ERIC Educational Resources Information Center

    Saba, Farhad, Ed.

    1999-01-01

    Completes a discussion of a systems model of distance education (in articles since May 1999) focusing on the most complex level, international. Discussion includes transfer of technology from United States universities to developing nations, the free market, and the age of the global economy. Presents a list of "early indicators" of changes in…

  17. Auditory system

    NASA Technical Reports Server (NTRS)

    Ades, H. W.

    1973-01-01

    The physical correlations of hearing, i.e. the acoustic stimuli, are reported. The auditory system, consisting of external ear, middle ear, inner ear, organ of Corti, basilar membrane, hair cells, inner hair cells, outer hair cells, innervation of hair cells, and transducer mechanisms, is discussed. Both conductive and sensorineural hearing losses are also examined.

  18. Instructional Systems.

    ERIC Educational Resources Information Center

    Banathy, Bela H.

    The underlying assumption of this book is that the systems approach has a dual role in education. "As applied 'in' education, it offers a powerful methodology for decisionmaking and design development. As applied 'to' education, it may bring about a clear understanding of what education is truly about." The essential purpose of the book is to…

  19. Immune System

    EPA Science Inventory

    A properly functioning immune system is essential to good health. It defends the body against infectious agents and in some cases tumor cells. Individuals with immune deficiencies resulting from genetic defects, diseases (e.g., AIDS, leukemia), or drug therapies are more suscepti...

  20. Systems Science

    ERIC Educational Resources Information Center

    Christakis, Alexander; Hammond, Debora; Jackson, Michael; Laszlo, Alexander; Mitroff, Ian; Snowden, Dave; Troncale, Len; Carr-Chellman, Alison; Spector, J. Michael; Wilson, Brent

    2013-01-01

    Scholars representing the field of systems science were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Alexander Christakis, Debora Hammond, Michael Jackson, Alexander Laszlo, Ian Mitroff, Dave…

  1. Exploring Enterprise, System of Systems, and System and Software Architectures

    DTIC Science & Technology

    2016-06-13

    2009 Carnegie Mellon University Exploring Enterprise, System of Systems, and System and Software Architectures Software Engineering Institute...TITLE AND SUBTITLE Exploring Enterprise, System of Systems, and System and Software Architectures 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Carnegie Mellon University, Software Engineering Institute,Pittsburgh,PA,15213 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY

  2. Surveying System

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Sunrise Geodetic Surveys are setting up their equipment for a town survey. Their equipment differs from conventional surveying systems that employ transit rod and chain to measure angles and distances. They are using ISTAC Inc.'s Model 2002 positioning system, which offers fast accurate surveying with exceptional signals from orbiting satellites. The special utility of the ISTAC Model 2002 is that it can provide positioning of the highest accuracy from Navstar PPS signals because it requires no knowledge of secret codes. It operates by comparing the frequency and time phase of a Navstar signal arriving at one ISTAC receiver with the reception of the same set of signals by another receiver. Data is computer processed and translated into three dimensional position data - latitude, longitude and elevation.

  3. Solar Systems

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The solar collectors shown are elements of domestic solar hot water systems produced by Solar One Ltd., Virginia Beach, Virginia. Design of these systems benefited from technical expertise provided Solar One by NASA's Langley Research Center. The company obtained a NASA technical support package describing the d e sign and operation of solar heating equipment in NASA's Tech House, a demonstration project in which aerospace and commercial building technology are combined in an energy- efficient home. Solar One received further assistance through personal contact with Langley solar experts. The company reports that the technical information provided by NASA influenced Solar One's panel design, its selection of a long-life panel coating which increases solar collection efficiency, and the method adopted for protecting solar collectors from freezing conditions.

  4. Gasification system

    DOEpatents

    Haldipur, Gaurang B.; Anderson, Richard G.; Cherish, Peter

    1983-01-01

    A method and system for injecting coal and process fluids into a fluidized bed gasification reactor. Three concentric tubes extend vertically upward into the fluidized bed. Coal particulates in a transport gas are injected through an inner tube, and an oxygen rich mixture of oxygen and steam are injected through an inner annulus about the inner tube. A gaseous medium relatively lean in oxygen content, such as steam, is injected through an annulus surrounding the inner annulus.

  5. Gasification system

    DOEpatents

    Haldipur, Gaurang B.; Anderson, Richard G.; Cherish, Peter

    1985-01-01

    A method and system for injecting coal and process fluids into a fluidized bed gasification reactor. Three concentric tubes extend vertically upward into the fluidized bed. Coal particulates in a transport gas are injected through an inner tube, and an oxygen rich mixture of oxygen and steam are injected through an inner annulus about the inner tube. A gaseous medium relatively lean in oxygen content, such as steam, is injected through an annulus surrounding the inner annulus.

  6. Imaging System

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The 1100C Virtual Window is based on technology developed under NASA Small Business Innovation (SBIR) contracts to Ames Research Center. For example, under one contract Dimension Technologies, Inc. developed a large autostereoscopic display for scientific visualization applications. The Virtual Window employs an innovative illumination system to deliver the depth and color of true 3D imaging. Its applications include surgery and Magnetic Resonance Imaging scans, viewing for teleoperated robots, training, and in aviation cockpit displays.

  7. Security system

    DOEpatents

    Baumann, Mark J.; Kuca, Michal; Aragon, Mona L.

    2016-02-02

    A security system includes a structure having a structural surface. The structure is sized to contain an asset therein and configured to provide a forceful breaching delay. The structure has an opening formed therein to permit predetermined access to the asset contained within the structure. The structure includes intrusion detection features within or associated with the structure that are activated in response to at least a partial breach of the structure.

  8. Tychonic System

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    The world system proposed in 1583 by the Danish astronomer Tycho Brahe (1546-1601). Unable to accept the Copernican doctrine that the Earth moves around the Sun, he put forward the view, later disproved by Kepler (1571-1630), that the planets move around the Sun, but the Sun and Moon move around the Earth. The theory explained the observed variations of the phases of Venus, for which the Ptolemai...

  9. Systemic Assurance

    DTIC Science & Technology

    2015-07-31

    to, warranty of fitness for purpose or merchantability, exclusivity, or results obtained from use of the material. Stevens Institute of Technology...customer organizations judge them fit for use in the mission environment. These assurance judgments must be based on evidence that a system manifests...which it is achieved. Assurance is a human judgment of fitness for use. This judgment is thus contextualized by the mission definition, the features

  10. Copernican System

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    The heliocentric (i.e. `Sun-centered') theory proposed by the Polish astronomer Nicolaus Copernicus (1473-1543), and published by him in 1543 in his book, De Revolutionibus Orbium Coelestium. In this system Copernicus placed the Sun at the center of the universe and regarded the Earth and the planets as moving around it in circular orbits. Because of his retention of the notion of circular motion...

  11. CONTROL SYSTEM

    DOEpatents

    Shannon, R.H.; Williamson, H.E.

    1962-10-30

    A boiling water type nuclear reactor power system having improved means of control is described. These means include provisions for either heating the coolant-moderator prior to entry into the reactor or shunting the coolantmoderator around the heating means in response to the demand from the heat engine. These provisions are in addition to means for withdrawing the control rods from the reactor. (AEC)

  12. Bioregenerative system

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The design course is an eight semester credit multi-disciplinary engineering design course taught primarily to Engineering Science, Aerospace, Electrical and Mechanical Engineering seniors. This year the course project involved the design of the three interrelated loops: atmospheric, liquid nutrient and solid waste management, associated with growing higher plants to support man during long-term space missions. The project is complementary to the NASA Kennedy Space Center Controlled Environmental Life Support System (CELSS) project. The first semester the class worked on a preliminary design for a complete system. This effort included means for monitoring and control of composition, temperature, flow rate, etc., for the atmosphere and liquid nutrient solution; disease and contaminant monitoring and control; plant mechanical support, propagation and harvesting; solid and liquid waste recycling; and system maintenance and refurbishing. The project has significant biological, mechanical, electrical and Al/Robotics aspects. The second semester a small number of subsystems or components, identified as important and interesting during the first semester, were selected for detail design, fabrication, and testing. The class was supported by close cooperation with The Kennedy Space Center and by two teaching assistants. The availability of a dedicated, well equipped project room greatly enhanced the communication and team spirit of the class.

  13. Braking system

    DOEpatents

    Norgren, D.U.

    1982-09-23

    A balanced braking system comprising a plurality of braking assemblies located about a member to be braked. Each of the braking assemblies consists of a spring biased piston of a first material fitted into a body of a different material which has a greater contraction upon cooling than the piston material. The piston is provided with a recessed head portion over which is positioned a diaphragm and forming a space therebetween to which is connected a pressurized fluid supply. The diaphragm is controlled by the fluid in the space to contact or withdraw from the member to be braked. A cooling means causes the body within which the piston is fitted to contract more than the piston, producing a tight shrink fit therebetween. The braking system is particularly applicable for selectively braking an arbor of an electron microscope which immobilizes, for example, a vertically adjustable low temperature specimen holder during observation. The system provides balanced braking forces which can be easily removed and re-established with minimal disturbance to arbor location.

  14. Accuracy of a Novel Noninvasive Transdermal Continuous Glucose Monitor in Critically Ill Patients

    PubMed Central

    Saur, Nicole M.; England, Michael R.; Menzie, Wayne; Melanson, Ann Marie; Trieu, My-Quyen; Berlin, Jason; Hurley, James; Krystyniak, Keith; Kongable, Gail L.

    2014-01-01

    Stress hyperglycemia and hypoglycemia are associated with increased morbidity and mortality in the critically ill. Intermittent, random blood glucose (BG) measurements can miss episodes of hyper- and hypoglycemia. The purpose of this study was to determine the accuracy of the Symphony® continuous glucose monitor (CGM) in critically ill cardiac surgery patients. Fifteen adult cardiac surgery patients were evaluated immediately postoperatively in the intensive care unit. Prelude® SkinPrep prepared the skin and a sensor was applied to 2 test sites on each subject to monitor interstitial fluid glucose. Reference BG was sampled at 30- to 60-minute intervals. The skin at the test sites was inspected for adverse effects. Accuracy of the retrospectively analyzed CGM data relative to reference BG values was determined using continuous glucose-error grid analysis (CG-EGA) and mean absolute relative difference (MARD). Using 570 Symphony CGM glucose readings paired with reference BG measurements, CG-EGA showed that 99.6% of the readings were within zones A and B. BG measurements ranged from 73 to 251 mg/dL. The MARD was 12.3%. No adverse device effects were reported. The Symphony CGM system is able to safely, continuously, and noninvasively monitor glucose in the transdermal interstitial fluid of cardiac surgery intensive care unit patients with accuracy similar to that reported with other CGM systems. Future versions of the system will need real-time data analysis, fast warm-up, and less frequent calibrations to be used in the clinical setting. PMID:24876448

  15. Balance System

    NASA Technical Reports Server (NTRS)

    1988-01-01

    TherEx Inc.'s AT-1 Computerized Ataxiameter precisely evaluates posture and balance disturbances that commonly accompany neurological and musculoskeletal disorders. Complete system includes two-strain gauged footplates, signal conditioning circuitry, a computer monitor, printer and a stand-alone tiltable balance platform. AT-1 serves as assessment tool, treatment monitor, and rehabilitation training device. It allows clinician to document quantitatively the outcome of treatment and analyze data over time to develop outcome standards for several classifications of patients. It can evaluate specifically the effects of surgery, drug treatment, physical therapy or prosthetic devices.

  16. Sterilization System

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Cox Sterile Products, Inc.'s Rapid Heat Transfer Sterilizer employs a heat exchange process that induces rapid air movement; the air becomes the heat transfer medium, maintaining a uniform temperature of 375 degrees Fahrenheit. It features pushbutton controls for three timing cycles for different instrument loads, a six-minute cycle for standard unpackaged instruments, eight minutes for certain specialized dental/medical instruments and 12 minutes for packaged instruments which can then be stored in a drawer in sterile condition. System will stay at 375 degrees all day. Continuous operation is not expensive because of the sterilizer's very low power requirements.

  17. Purification system

    NASA Technical Reports Server (NTRS)

    Flanagan, David T. (Inventor); Gibbons, Randall E. (Inventor)

    1992-01-01

    A system for prolonging the life of a granulated activated charcoal (GAC) water treatment device is disclosed in which an ultraviolet light transparent material is used to constrain water to flow over carbon surfaces. It is configured to receive maximum flux from a UV radiation source for the purpose of preventing microbial proliferation on the carbon surfaces; oxidizing organic contaminants adsorbed from the water onto the carbon surfaces and from biodegradation of adsorbed microbial forms; disinfecting water; and oxidizing organic contaminants in the water.

  18. Relaxation System

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Environ Corporation's relaxation system is built around a body lounge, a kind of super easy chair that incorporates sensory devices. Computer controlled enclosure provides filtered ionized air to create a feeling of invigoration, enhanced by mood changing aromas. Occupant is also surrounded by multidimensional audio and the lighting is programmed to change colors, patterns, and intensity periodically. These and other sensory stimulators are designed to provide an environment in which the learning process is stimulated, because research has proven that while an individual is in a deep state of relaxation, the mind is more receptive to new information.

  19. Systems Pharmacology

    PubMed Central

    Boran, Aislyn D. W.; Iyengar, Ravi

    2011-01-01

    We examine how physiology and pathophysiology are studied from a systems perspective, using high-throughput experiments and computational analysis of regulatory networks. We describe the integration of these analyses with pharmacology, which leads to new understanding of drug action and enables drug discovery for complex diseases. Network studies of drug-target relationships can serve as an indication on the general trends in the approved drugs and the drug-discovery progress. There is a growing number of targeted therapies approved and in the pipeline, which meets a new set of problems with efficacy and adverse effects. The pitfalls of these mechanistically based drugs are described, along with how a systems view of drug action is increasingly important to uncover intricate signaling mechanisms that play an important part in drug action, resistance mechanisms, and off-target effects. Computational methodologies enable the classification of drugs according to their structures and to which proteins they bind. Recent studies have combined the structural analyses with analysis of regulatory networks to make predictions about the therapeutic effects of drugs for complex diseases and possible off-target effects. PMID:20687178

  20. Transfer system

    DOEpatents

    Kurosawa, Kanji; Koga, Bunichiro; Ito, Hideki; Kiriyama, Shigeru; Higuchi, Shizuo

    2003-05-20

    A transport system includes a traveling rail (1) which constitutes a transport route and a transport body (3) which is capable of traveling on the traveling rail in the longitudinal direction of the traveling rail. Flexible drive tubes (5) are arranged on the traveling rail in the longitudinal direction of the traveling rail. The transport body includes a traveling wheel (4) which is capable of rolling on the traveling rail and drive wheels (2) which are capable of rolling on the drive tubes upon receiving the rotational drive power generated by pressure of a pressure medium supplied to the drive tubes while depressing the drive tubes. The traveling rail includes a plurality of transport sections and the transport body is capable of receiving a rotational drive force from the drive tubes at every transport sections. If necessary, a transport route changeover switch which changes over the transport route can be provided between the transport sections.

  1. Power systems

    NASA Astrophysics Data System (ADS)

    Kaplan, G.

    1982-01-01

    Significant events in current, prototype, and experimental utility power generating systems in 1981 are reviewed. The acceleration of licensing and the renewal of plans for reprocessing of fuel for nuclear power plants are discussed, including the rise of French reactor-produced electricity to over 40% of the country's electrical output. A 4.5 MW fuel cell neared completion in New York City, while three 2.5 MW NASA-designed windpowered generators began producing power in the state of Washington. Static bar compensators, nonflammable-liquid cooled power transformers, and ZnO surge arrestors were used by utilities for the first time, and the integration of a coal gasifier-combined cycle power plant approached the planning phase. An MHD generator was run for 1000 hours and produced 50-60 kWe, while a 20 MVA superconducting generator was readied for testing.

  2. Pumping system

    SciTech Connect

    Kime, J.A.

    1987-05-19

    This patent describes a gas-oil production system for pumping formation fluid in a well through a tubing string within which a down hole pump connects to a hydraulic stroking device through a rod string providing the pump including a plunger reciprocally driven by the hydraulic stroking device toward an upper terminal position during a plunger upstroke. The rod string normally supports the weight of a column of fluid and toward a lower terminal position at the end of a plunger downstroke during which the weight of the column fluid is normally transferred to the tubing string through fluid within the pump. The method for detecting when the well is pumped off comprises: supplying working fluid to the hydraulic stroking device to raise the hydraulic stroking device and thereby move the plunger from the lower terminal position to the upper terminal position; and removing the working fluid at a controlled rate from the hydraulic stroking device.

  3. Systems toxicology.

    PubMed

    Hartung, Thomas; van Vliet, Erwin; Jaworska, Joanna; Bonilla, Leo; Skinner, Nigel; Thomas, Russell

    2012-01-01

    The need for a more mechanistic understanding of the ways in which chemicals modulate biological pathways is urgent if we are to identify and better assess safety issues relating to a wide range of substances developed by the pharmaceutical, chemical, agri-bio, and cosmetic industries. Omics technologies provide a valuable opportunity to refine existing methods and provide information for so-called integrated testing strategies via the creation of signatures of toxicity. By mapping these signatures to underlying pathways of toxicity, some of which have been identified by toxicologists over the last few decades, and bringing them together with pathway information determined from biochemistry and molecular biology, a "systems toxicology" approach will enable virtual experiments to be conducted that can improve the prediction of hazard and the assessment of compound toxicity.

  4. Release of ammonia from HAN-type PHA

    SciTech Connect

    Zamecnik, J.R.

    1992-06-10

    A preliminary design basis for ammonia scrubbers in the DWPF has been issued. This design basis is based on a theoretical model of ammonia evolution from the SRAT, SME and RCT. It is desirable to acquire actual process data on ammonia evolution prior to performing detailed design of scrubbers for DWPF. The evolution of ammonia from the SRAT and SME in the Integrated DWPF Melter System (IDMS) was investigated during the HM4 run. In this run, Precipitate Hydrolysis Aqueous (PHA), which was made in the Precipitate Hydrolysis Experimental Facility (PHEF) using the HAN (hydroxylamine nitrate) process was used, thus resulting in PHA with a high concentration of ammonium ion.

  5. CURRENT STATUS OF INDIVIDUAL DOSIMETRIC MONITORING IN UKRAINE.

    PubMed

    Chumak, V; Deniachenko, N; Makarovska, O; Mihailescu, L-C; Prykhodko, A; Voloskyi, V; Vanhavere, F

    2016-09-01

    About 50 000 workers are being occupationally exposed to radiation in Ukraine. Individual dosimetric monitoring (IDM) is provided by 77 dosimetry services and laboratories of very different scale with a number of monitored workers ranging from several persons to ∼9000. In the present work, the current status of personal dosimetry in Ukraine was studied. The First National Intercomparison (FNI) of the IDM labs was accompanied by a survey of the laboratory operation in terms of coverage, types of dosimetry provided, instrumentation and methodologies used, metrological support, data recording, etc. Totally, 34 laboratories responded to the FNI call, and 18 services with 19 different personal dosimetry systems took part in the intercomparison exercise providing 24 dosimeters each for blind irradiation to photons of 6 different qualities (ISO N-series X-rays, S-Cs and S-Co sources) in a dose range of 5-60 mSv. Performance of the dosimetry labs was evaluated according to ISO 14146 criteria of matching trumpet curves with H0 = 0.2 mSv. The test revealed that 8 of the 19 systems meet ISO 14146 criteria in full, 5 other labs show marginal performance and 6 laboratories demonstrated catastrophic quality of dosimetric results. Altogether, 18 participating labs provide dosimetric monitoring to 37 477 workers (about three-fourths of all occupationally exposed workers), usually on monthly (nuclear industry) or quarterly (rest of applications) basis. Of this number, 20 664 persons (55 %) receive completely adequate individual monitoring, and the number of personnel receiving IDM of inadequate quality counts 3054 persons.

  6. Force adaptation transfers to untrained workspace regions in children: evidence for developing inverse dynamic motor models.

    PubMed

    Jansen-Osmann, Petra; Richter, Stefanie; Konczak, Jürgen; Kalveram, Karl-Theodor

    2002-03-01

    When humans perform goal-directed arm movements under the influence of an external damping force, they learn to adapt to these external dynamics. After removal of the external force field, they reveal kinematic aftereffects that are indicative of a neural controller that still compensates the no longer existing force. Such behavior suggests that the adult human nervous system uses a neural representation of inverse arm dynamics to control upper-extremity motion. Central to the notion of an inverse dynamic model (IDM) is that learning generalizes. Consequently, aftereffects should be observable even in untrained workspace regions. Adults have shown such behavior, but the ontogenetic development of this process remains unclear. This study examines the adaptive behavior of children and investigates whether learning a force field in one hemifield of the right arm workspace has an effect on force adaptation in the other hemifield. Thirty children (aged 6-10 years) and ten adults performed 30 degrees elbow flexion movements under two conditions of external damping (negative and null). We found that learning to compensate an external damping force transferred to the opposite hemifield, which indicates that a model of the limb dynamics rather than an association of visited space and experienced force was acquired. Aftereffects were more pronounced in the younger children and readaptation to a null-force condition was prolonged. This finding is consistent with the view that IDMs in children are imprecise neural representations of the actual arm dynamics. It indicates that the acquisition of IDMs is a developmental achievement and that the human motor system is inherently flexible enough to adapt to any novel force within the limits of the organism's biomechanics.

  7. Separation system

    DOEpatents

    Rubin, Leslie S.

    1986-01-01

    A separation system for dewatering radioactive waste materials includes a disposal container, drive structure for receiving the container, and means for releasably attaching the container to the drive structure. Separation structure disposed in the container adjacent the inner surface of the side wall structure retains solids while allowing passage of liquids. Inlet port structure in the container top wall is normally closed by first valve structure that is centrifugally actuated to open the inlet port and discharge port structure at the container periphery receives liquid that passes through the separation structure and is normally closed by second valve structure that is centrifugally actuated to open the discharge ports. The container also includes coupling structure for releasable engagement with the centrifugal drive structure. Centrifugal force produced when the container is driven in rotation by the drive structure opens the valve structures, and radioactive waste material introduced into the container through the open inlet port is dewatered, and the waste is compacted. The ports are automatically closed by the valves when the container drum is not subjected to centrifugal force such that containment effectiveness is enhanced and exposure of personnel to radioactive materials is minimized.

  8. Incinerator system

    SciTech Connect

    Rathmell, R.K.

    1986-10-07

    An incineration system is described which consists of: combustion chamber structure having an inlet, an outlet, and burner structure in the combustion chamber, heat exchanger structure defining a chamber, divider structure between the heat exchanger chamber and the combustion chamber, an array of tubes extending through the heat exchanger chamber to the inlet of the combustion chamber at the divider structure. The heat exchanger chamber has an inlet coupled to the outlet of the combustion chamber for flow of the combustion products discharged from the combustion chamber through the heat exchanger chamber over the tubes in heat exchange relation, and an outlet for discharge of products from the heat exchanger chamber, aspirator sleeve structure secured to the divider structure between the heat exchanger chamber and the combustion chamber. Each aspirator sleeve receives the outlet end of a heat exchanger tube in slip fit relation so that the heat exchanger tubes are free to thermally expand longitudinally within the aspirator sleeves, and means for flowing vapor through the heat exchanger tubes into the combustion chamber at sufficiently high velocity to produce a reduced pressure effect in the aspirator sleeves in the heat exchanger chamber to draw a minor fraction of combustion products through the aspirator sleeves into the combustion chamber for reincineration.

  9. Systemic vasculitis.

    PubMed

    Sharma, Poonam; Sharma, Sanjeev; Baltaro, Richard; Hurley, John

    2011-03-01

    The systemic vasculitides are characterized by inflammation of blood vessel walls. Vessels of any type, in any organ can be affected, resulting in a broad spectrum of signs and symptoms. The heterogenous nature of vasculitides presents a diagnostic challenge. The American College of Rheumatology classification criteria and the Chapel Hill Consensus Conference nomenclature are the most widely used to distinguish different forms of vasculitis. The Chapel Hill Consensus Conference nomenclature defines 10 primary vasculitides based on vessel size (large, medium, and small). The diagnosis relies on the recognition of a compatible clinical presentation supported by specific laboratory or imaging tests and confirmatory histology. Antineutrophilic cytoplasmic antibody testing has been of particular benefit in defining a subgroup of small vessel vasculitides. Treatment is based on clinical presentation and the pattern of organ involvement. Glucocorticoids are the primary treatment for many forms of vasculitis. Additional immunosuppressive agents, including methotrexate and cyclophosphamide, are sometimes required. Newer approaches, such as the use of anti-tumor necrosis factor or B cell therapies, are being tried in resistant cases. Patients can experience considerable treatment-related toxicity, especially infection from immunosuppressive therapy and adverse effects from steroids (e.g., osteoporosis, diabetes mellitus, cataract). Vitamin D and calcium prophylaxis are recommended in patients on long-term steroid therapy.

  10. Endocrine System (For Teens)

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Endocrine System KidsHealth > For Teens > Endocrine System A A A ... is called the endocrine system . What Is the Endocrine System? Although we rarely think about the endocrine system, ...

  11. New Systems Produced by Systemic Change

    ERIC Educational Resources Information Center

    Battino, Wendy; Clem, Jo; Caine, Renate N.; Reigeluth, Charles M.; Chapman, Carrie; Flinders, David J.; Malopinsky, Larissa V.

    2006-01-01

    This article presents new systems produced by systemic change. First is Systemic Changes in the Chugach School District by Wendy Battino and Jo Clem. Second is Systemic Changes in Public Schools through Brain-Based Learning by Renate N. Caine. Third is A Vision of an Information-Age Educational System by Charles M. Reigeluth. Fourth is Systemic…

  12. Airborne Global Positioning System Antenna System

    DTIC Science & Technology

    2004-10-14

    GLOBAL POSITIONING SYSTEM ANTENNA SYSTEM DISTRIBUTION: SMC/ GP (3 cys); AFFSA...standard that airborne Global Positioning System ( GPS ) antenna system must meet to be identified with the applicable MSO marking. The similarity of...UNCLASSIFIED DOCUMENT NO. DATE NO. MSO-C144 14 Oct 04 Initial Release REV: REV: SHEET 1 OF 16 TITLE: AIRBORNE GLOBAL POSITIONING SYSTEM

  13. Contents of selected B vitamins in NIST SRM 3280 multivitamin/multielement tablets by liquid chromatography isotope dilution mass spectrometry.

    PubMed

    Chen, Pei; Ozcan, Mustafa; Wolf, Wayne R

    2007-09-01

    There is increased interest in accurately assessing the total dietary intake of vitamins from all sources, including foods and dietary supplements. Consequently, a Dietary Supplement Ingredient Database (DSID), based upon analytical values, is being established by USDA with support of the Office of Dietary Supplements (ODS), NIH. The DSID necessitated the development of a new SRM, 3280--Multivitamin/Multimineral Tablets, by the National Institute of Standards and Technology (NIST), with support from the ODS. As a continuation of a long-term project to develop and validate new methods of determining water-soluble B vitamins in foods and dietary supplements, and as part of a collaborative effort with NIST to characterize SRM 3280, values for the vitamin contents of SRM 3280 have been generated by a liquid chromatographic isotope dilution mass spectrometric (LC/IDMS) method. Isotope-labeled ((13)C and/or (2)H) B vitamins (B1-thiamine, B6-pyridoxine, B3-nicotinamide, and B5-pantothenic acid) were obtained from commercial sources, with the support of the ODS/NIH. Our LC/IDMS method uses a C18 reversed phase column, an Agilent 1100 HPLC system, and a Quattro Micro triple-quad mass spectrometer (MS). B vitamin determination was achieved using a gradient LC profile combined with MS/MS detection in multiple reaction monitoring mode. Stock solutions of the isotope-labeled vitamins were calibrated against USP standard solutions. The SRM tablets, with added amounts of the four isotope-labeled B vitamins, were extracted and the vitamins simultaneously determined in a single LC run, in contrast with the single-component determinations performed via IDMS. Unknown vitamin concentrations were calculated by comparing the ratios of the integrated LC peaks at the different masses of the unlabeled and labeled vitamins.

  14. RADAR WARNING SYSTEM,

    DTIC Science & Technology

    RADAR TRACKING, *AIRCRAFT DEFENSE SYSTEMS, RADAR EQUIPMENT, AIR TO AIR, SEARCH RADAR, GUIDED MISSILES, HIGH SPEED BOMBING, EARLY WARNING SYSTEMS, FIRE CONTROL SYSTEM COMPONENTS, AIRCRAFT, TIME, CHINA.

  15. System design description cone penetrometer system

    SciTech Connect

    Seda, R.Y., Westinghouse Hanford

    1996-08-12

    The system design description documents in detail the design of the cone penetrometer system. The systems includes the cone penetrometer physical package, raman spectroscopy package and moisture sensor package. Information pertinent to the system design, development, fabrication and testing is provided.

  16. Networked control of microgrid system of systems

    NASA Astrophysics Data System (ADS)

    Mahmoud, Magdi S.; Rahman, Mohamed Saif Ur; AL-Sunni, Fouad M.

    2016-08-01

    The microgrid has made its mark in distributed generation and has attracted widespread research. However, microgrid is a complex system which needs to be viewed from an intelligent system of systems perspective. In this paper, a network control system of systems is designed for the islanded microgrid system consisting of three distributed generation units as three subsystems supplying a load. The controller stabilises the microgrid system in the presence of communication infractions such as packet dropouts and delays. Simulation results are included to elucidate the effectiveness of the proposed control strategy.

  17. From systems biology to systems biomedicine.

    PubMed

    Antony, Paul M A; Balling, Rudi; Vlassis, Nikos

    2012-08-01

    Systems Biology is about combining theory, technology, and targeted experiments in a way that drives not only data accumulation but knowledge as well. The challenge in Systems Biomedicine is to furthermore translate mechanistic insights in biological systems to clinical application, with the central aim of improving patients' quality of life. The challenge is to find theoretically well-chosen models for the contextually correct and intelligible representation of multi-scale biological systems. In this review, we discuss the current state of Systems Biology, highlight the emergence of Systems Biomedicine, and highlight some of the topics and views that we think are important for the efficient application of Systems Theory in Biomedicine.

  18. Global Positioning System Shipborne Reference System

    DTIC Science & Technology

    1997-09-30

    Office of Naval Research Space and Remote Sensing 1997 Annual Report 1 GLOBAL POSITIONING SYSTEM SHIPBORNE REFERENCE SYSTEM James R. Clynch...N00014-97-WR30044 LONG-TERM GOAL The long term goal is to improve the navigation capability of naval vessels using the Global Positioning System ...COVERED 00-00-1997 to 00-00-1997 4. TITLE AND SUBTITLE Global Positioning System Shipborne Reference System 5a. CONTRACT NUMBER 5b. GRANT

  19. Mechanical systems: A compilation

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A compilation of several mechanized systems is presented. The articles are contained in three sections: robotics, industrial mechanical systems, including several on linear and rotary systems and lastly mechanical control systems, such as brakes and clutches.

  20. Endocrine System (For Parents)

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Endocrine System KidsHealth > For Parents > Endocrine System A A A ... to help the body function properly. About the Endocrine System The foundations of the endocrine system are the ...

  1. Immune System (For Parents)

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Immune System KidsHealth > For Parents > Immune System A A A ... can lead to illness and infection. About the Immune System The immune system is the body's defense against ...

  2. Quantify information system benefits

    SciTech Connect

    Koppel, L.B.

    1995-06-01

    What are information systems and how do they relate to control systems? How do information systems produce benefits in hydrocarbon processing? What are some examples of benefit-generating information system applications? Information System Benefits (ISBEN) is a structured methodology for estimating information system benefits in hydrocarbon processing. The paper discusses information and control systems, information system benefits and applications, objectives, strategies and measures of ISBEN, ISBEN business drivers, ISBEN database, ISBEN methodology, and implementation.

  3. Data Systems Task Analysis.

    DTIC Science & Technology

    1979-08-01

    A08873 MARINE CORPS WASHINGTON DC F/B 5/9 DATA SYSTEMS TASK ANALYSIS. (U) "CLASSIFIEO. -%mm . LEVELIs DATA SYSTEMS O0 TASK ANALYSIS DCI) OO JF AUG 28...TECI-NICIAN jl. CCMPUTER SYSTEMS EVALLATOR ,13. LCMPUTER SYSTEMS MANAGER 314. LCMPUTER SYSTEMS MCNITOR A5o LCMPUTER TERMINAL OPERATOR j16. LCNFIGURATION...OPERATOR )27. DATA PROCESSING NCO )28. DATA PROCESSINIG TECHNICIAN 329e DATA SYSTEMS LIBRARIAN )35* DATA SYSTEMS OPERATICNS Cl-IEF 331. DATA SYSTEMS

  4. Practical systems thinking

    NASA Astrophysics Data System (ADS)

    Konkarikoski, K.; Ritala, R.; Ihalainen, H.

    2010-07-01

    System is a dynamic and complex whole, interacting as a structured functional unit. Systems thinking provides tools for understanding a such system structure and its dynamic behavior. Practical systems thinking course teaches first year bachelor students basics about systems and how open problem can be formulated to system task.

  5. System of systems modeling and analysis.

    SciTech Connect

    Campbell, James E.; Anderson, Dennis James; Longsine, Dennis E.; Shirah, Donald N.

    2005-01-01

    This report documents the results of an LDRD program entitled 'System of Systems Modeling and Analysis' that was conducted during FY 2003 and FY 2004. Systems that themselves consist of multiple systems (referred to here as System of Systems or SoS) introduce a level of complexity to systems performance analysis and optimization that is not readily addressable by existing capabilities. The objective of the 'System of Systems Modeling and Analysis' project was to develop an integrated modeling and simulation environment that addresses the complex SoS modeling and analysis needs. The approach to meeting this objective involved two key efforts. First, a static analysis approach, called state modeling, has been developed that is useful for analyzing the average performance of systems over defined use conditions. The state modeling capability supports analysis and optimization of multiple systems and multiple performance measures or measures of effectiveness. The second effort involves time simulation which represents every system in the simulation using an encapsulated state model (State Model Object or SMO). The time simulation can analyze any number of systems including cross-platform dependencies and a detailed treatment of the logistics required to support the systems in a defined mission.

  6. System Software Framework for System of Systems Avionics

    NASA Technical Reports Server (NTRS)

    Ferguson, Roscoe C.; Peterson, Benjamin L; Thompson, Hiram C.

    2005-01-01

    Project Constellation implements NASA's vision for space exploration to expand human presence in our solar system. The engineering focus of this project is developing a system of systems architecture. This architecture allows for the incremental development of the overall program. Systems can be built and connected in a "Lego style" manner to generate configurations supporting various mission objectives. The development of the avionics or control systems of such a massive project will result in concurrent engineering. Also, each system will have software and the need to communicate with other (possibly heterogeneous) systems. Fortunately, this design problem has already been solved during the creation and evolution of systems such as the Internet and the Department of Defense's successful effort to standardize distributed simulation (now IEEE 1516). The solution relies on the use of a standard layered software framework and a communication protocol. A standard framework and communication protocol is suggested for the development and maintenance of Project Constellation systems. The ARINC 653 standard is a great start for such a common software framework. This paper proposes a common system software framework that uses the Real Time Publish/Subscribe protocol for framework-to-framework communication to extend ARINC 653. It is highly recommended that such a framework be established before development. This is important for the success of concurrent engineering. The framework provides an infrastructure for general system services and is designed for flexibility to support a spiral development effort.

  7. Intelligent systems technology infrastructure for integrated systems

    NASA Technical Reports Server (NTRS)

    Lum, Henry, Jr.

    1991-01-01

    Significant advances have occurred during the last decade in intelligent systems technologies (a.k.a. knowledge-based systems, KBS) including research, feasibility demonstrations, and technology implementations in operational environments. Evaluation and simulation data obtained to date in real-time operational environments suggest that cost-effective utilization of intelligent systems technologies can be realized for Automated Rendezvous and Capture applications. The successful implementation of these technologies involve a complex system infrastructure integrating the requirements of transportation, vehicle checkout and health management, and communication systems without compromise to systems reliability and performance. The resources that must be invoked to accomplish these tasks include remote ground operations and control, built-in system fault management and control, and intelligent robotics. To ensure long-term evolution and integration of new validated technologies over the lifetime of the vehicle, system interfaces must also be addressed and integrated into the overall system interface requirements. An approach for defining and evaluating the system infrastructures including the testbed currently being used to support the on-going evaluations for the evolutionary Space Station Freedom Data Management System is presented and discussed. Intelligent system technologies discussed include artificial intelligence (real-time replanning and scheduling), high performance computational elements (parallel processors, photonic processors, and neural networks), real-time fault management and control, and system software development tools for rapid prototyping capabilities.

  8. [X-33 Systems

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Lockheed Martin Skunk Works has compiled an Annual Performance Report of the X-33/RLV Program. This report consists of individual reports from all industry team members, as well as NASA team centers. This portion of the report is comprised of a status report of Allied-Signal Aerospace's contribution to the program. The following is a summary of the work reviewed under their portion of the agreement: (1) Communication Systems; (2) Environmental Control Systems- Active Thermal Control System (ATCS), Purge and Vent System, Hydrogen Detection System (HDS), Avionics Bay Inerting System (ABIS), and Flush Air Data System (FADS); (2) Landing Systems; (3) Power Management and Generation Systems; (4) Flight Control Actuation System (FCAS)- Electric Power Control & Distribution System (EPCDS), and Battery Power System (BPS); and (5) Vehicle Management Systems (VMS)- VMS Hardware, VMS Software Development Activities, and System Integration Laboratory (SIL).

  9. Systems engineering and analysis

    SciTech Connect

    Blanchard, B.S.; Fabrycky, W.J.

    1981-01-01

    An introduction to systems is provided and tools for systems analysis are considered, taking into account system definitions and concepts, approaches for bringing systems into being, models in systems analysis, economic analysis techniques, mathematical modeling and optimization, probability and statistics, queuing theory and analysis, and control concepts and techniques. The system design process is discussed along with the design for operational feasibility, systems engineering management, and system design case studies. Attention is given to conceptual design, preliminary system design, detail design and development, system test and evaluation, design for reliability, design for maintainability, design for supportability, design for economic feasibility, communication system design, finite population system design, energy storage system design, and procurement-inventory system design.

  10. Language as a System of Systems

    ERIC Educational Resources Information Center

    Mulder, J. W. F.; Hervey, S. G. J.

    1975-01-01

    Based on Mulder's previous classification of all semiotic systems designed to describe the system of discrete features in human languages, this article explores a further subclassification of the genus language into species. (CLK)

  11. Freedom System Text and Graphics System (TAGS)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Text and Graphics System (TAGS) is a high-resolution facsimile system that scans text or graphics material and converts the analog SCAN data into serial digital data. This video shows the TAGS in operation.

  12. Army Data Services Layer (ADSL) - Data Mediation Service (DMS)

    DTIC Science & Technology

    2008-12-01

    following instances: Baroque , Bebop, Rock, Trance, Sonata, Symphony, 12-Bar Blues, Concerto, and French Dance Suite. An RDF SubClass, “classical_music” (in...its common usage) describes the following set of instances: Baroque , Sonata, Symphony, Concerto, and French Dance Suite. Here, we see that the...B. Therefore, (A ⊆ B) ≡ (B ⊆ A) , where A = { Baroque , Bebop, Rock, Trance, Sonata, Symphony, 12-Bar Blues, Concerto, French Dance Suite

  13. LCLS XTOD Attenuator System System Concept Report

    SciTech Connect

    Kishiyama, K; Roeben, M; Trent, J; Ryutov, D; Shen, S

    2006-04-12

    The attenuator system for the Linac Coherent Light Source (LCLS) X-ray Transport, Optics and Diagnostics (XTOD) system has been configured and analyzed by the Lawrence Livermore National Laboratory's New Technologies Engineering Division (NTED) as requested by the SLAC/LCLS program. The system layout, performance analyses and selection of the vacuum components are presented in this System Conceptual Review (SCR) report. Also included are the plans for prototype, procurement, mechanical integration, and the cost estimates.

  14. Systems Theory, Systems Technology, and Curriculum Design.

    ERIC Educational Resources Information Center

    Pratt, David

    1978-01-01

    John Goodlad (1958) stated that "Nowhere in education is there greater need for a conceptual system to guide decision-making than the field of curriculum." This research attempts to explore ways in which systems thinking can provide a conceptual system, to illuminate the study of curriculum and guide the design of curricula. (Author/RK)

  15. Intelligent tutoring systems for systems engineering methodologies

    NASA Technical Reports Server (NTRS)

    Meyer, Richard J.; Toland, Joel; Decker, Louis

    1991-01-01

    The general goal is to provide the technology required to build systems that can provide intelligent tutoring in IDEF (Integrated Computer Aided Manufacturing Definition Method) modeling. The following subject areas are covered: intelligent tutoring systems for systems analysis methodologies; IDEF tutor architecture and components; developing cognitive skills for IDEF modeling; experimental software; and PC based prototype.

  16. Systems Intelligence Inventory

    ERIC Educational Resources Information Center

    Törmänen, Juha; Hämäläinen, Raimo P.; Saarinen, Esa

    2016-01-01

    Purpose: Systems intelligence (SI) (Saarinen and Hämäläinen, 2004) is a construct defined as a person's ability to act intelligently within complex systems involving interaction and feedback. SI relates to our ability to act in systems and reason about systems to adaptively carry out productive actions within and with respect to systems such as…

  17. Collaborative Systems Testing

    ERIC Educational Resources Information Center

    Pocatilu, Paul; Ciurea, Cristian

    2009-01-01

    Collaborative systems are widely used today in various activity fields. Their complexity is high and the development involves numerous resources and costs. Testing collaborative systems has a very important role for the systems' success. In this paper we present taxonomy of collaborative systems. The collaborative systems are classified in many…

  18. Systems Engineering Measurement Primer

    DTIC Science & Technology

    1998-03-01

    Systems Engineering Measurement Primer A Basic Introduction to Systems Engineering Measurement Concepts and Use Version 1.0 March 1998 This document...Federal Systems Garry Roedler Lockheed Martin Management & Data Systems Cathy Tilton The National Registry, Inc. E. Richard Widmann Raytheon Systems...IV 1. INTRODUCTION

  19. Intelligent test integration system

    NASA Technical Reports Server (NTRS)

    Sztipanovits, J.; Padalkar, S.; Rodriguez-Moscoso, J.; Kawamura, K.; Purves, B.; Williams, R.; Biglari, H.

    1988-01-01

    A new test technology is described which was developed for space system integration. The ultimate purpose of the system is to support the automatic generation of test systems in real time, distributed computing environments. The Intelligent Test Integration System (ITIS) is a knowledge based layer above the traditional test system components which can generate complex test configurations from the specification of test scenarios.

  20. Systems Measures of Water Distribution System Resilience

    SciTech Connect

    Klise, Katherine A.; Murray, Regan; Walker, La Tonya Nicole

    2015-01-01

    Resilience is a concept that is being used increasingly to refer to the capacity of infrastructure systems to be prepared for and able to respond effectively and rapidly to hazardous events. In Section 2 of this report, drinking water hazards, resilience literature, and available resilience tools are presented. Broader definitions, attributes and methods for measuring resilience are presented in Section 3. In Section 4, quantitative systems performance measures for water distribution systems are presented. Finally, in Section 5, the performance measures and their relevance to measuring the resilience of water systems to hazards is discussed along with needed improvements to water distribution system modeling tools.

  1. DDL system: Design systhesis of digital systems

    NASA Technical Reports Server (NTRS)

    Shiva, S. G.

    1983-01-01

    Digital Systems Design Language was integrated into the CADAT system environment of NASA-MSFC. The major technical aspects of this integration are summarized. Automatic hardware synthesis is now possible starting with a high level description of the system to be synthesized. The DDL system provides a high level design verification capability, thereby minimizing design changes in the later stages of the design cycle. An overview of the DDL system covering the translation, simulation and synthesis capabilities is provided. Two companion documents (the user's and programmer's manuals) are to be consulted for detailed discussions.

  2. Microwave landing system autoland system analysis

    NASA Technical Reports Server (NTRS)

    Feather, J. B.; Craven, B. K.

    1991-01-01

    The objective was to investigate the ability of present day aircraft equipped with automatic flight control systems to fly advanced Microwave Landing Systems (MLS) approaches. The tactical approach used to achieve this objective included reviewing the design and autoland operation of the MD-80 aircraft, simulating the MLS approaches using a batch computer program, and assessing the performance of the autoland system from computer generated data. The results showed changes were required to present Instrument Landing System (ILS) procedures to accommodate the new MLS curved paths. It was also shown that in some cases, changes to the digital flight guidance systems would be required so that an autoland could be performed.

  3. Lighting system with thermal management system

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Stecher, Thomas Elliot; Seeley, Charles Erklin; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Utturkar, Yogen Vishwas; Sharma, Rajdeep; Prabhakaran, Satish; Icoz, Tunc

    2015-08-25

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system is configured to provide an air flow, such as a unidirectional air flow, through the housing structure in order to cool the light source. The driver electronics are configured to provide power to each of the light source and the thermal management system.

  4. Lighting system with thermal management system

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Stecher, Thomas Elliot; Seeley, Charles Erklin; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Utturkar, Yogen Vishwas; Sharma, Rajdeep; Prabhakaran, Satish; Icoz, Tunc

    2015-02-24

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system is configured to provide an air flow, such as a unidirectional air flow, through the housing structure in order to cool the light source. The driver electronics are configured to provide power to each of the light source and the thermal management system.

  5. Lighting system with thermal management system

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Stecher, Thomas Elliot; Seeley, Charles Erklin; Kuenzler, Glenn Howard; Wolfe, Jr, Charles Franklin; Utturkar, Yogen Vishwas; Sharma, Rajdeep; Prabhakaran, Satish; Icoz, Tunc

    2016-10-11

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system is configured to provide an air flow, such as a unidirectional air flow, through the housing structure in order to cool the light source. The driver electronics are configured to provide power to each of the light source and the thermal management system.

  6. Lighting system with thermal management system

    DOEpatents

    Arik, Mehmet; Weaver, Stanton; Stecher, Thomas; Seeley, Charles; Kuenzler, Glenn; Wolfe, Jr., Charles; Utturkar, Yogen; Sharma, Rajdeep; Prabhakaran, Satish; Icoz, Tunc

    2013-05-07

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system is configured to provide an air flow, such as a unidirectional air flow, through the housing structure in order to cool the light source. The driver electronics are configured to provide power to each of the light source and the thermal management system.

  7. The LSST: A System of Systems

    NASA Astrophysics Data System (ADS)

    Claver, Chuck F.; Debois-Felsmann, G. P.; Delgado, F.; Hascall, P.; Marshall, S.; Nordby, M.; Schumacher, G.; Sebag, J.; LSST Collaboration

    2011-01-01

    The Large Synoptic Survey Telescope (LSST) is a complete observing system that acquires and archives images, processes and analyzes them, and publishes reduced images and catalogs of sources and objects. The LSST will operate over a ten year period producing a survey of 20,000 square degrees over the entire [Southern] sky in 6 filters (ugrizy) with each field having been visited several hundred times enabling a wide spectrum of science from fast transients to exploration of dark matter and dark energy. The LSST itself is a complex system of systems consisting of the 8.4m 3-mirror telescope, a 3.2 billion pixel camera, and a peta-scale data management system. The LSST project uses a Model Based Systems Engineering (MBSE) methodology to ensure an integrated approach to system design and rigorous definition of system interfaces and specifications. The MBSE methodology is applied through modeling of the LSST's systems with the System Modeling Language (SysML). The SysML modeling recursively establishes the threefold relationship between requirements, logical & physical functional decomposition and definition, and system and component behavior at successively deeper level of abstraction and detail. The LSST modeling includes the analysis and documenting the flow of command and control information and data between the suite of systems in the LSST observatory that are needed to carry out the activities of the survey. The MBSE approach is applied throughout all stages of the project from design, to validation and verification, though to commissioning.

  8. Systems Architecture for a Nationwide Healthcare System.

    PubMed

    Abin, Jorge; Nemeth, Horacio; Friedmann, Ignacio

    2015-01-01

    From a national level to give Internet technology support, the Nationwide Integrated Healthcare System in Uruguay requires a model of Information Systems Architecture. This system has multiple healthcare providers (public and private), and a strong component of supplementary services. Thus, the data processing system should have an architecture that considers this fact, while integrating the central services provided by the Ministry of Public Health. The national electronic health record, as well as other related data processing systems, should be based on this architecture. The architecture model described here conceptualizes a federated framework of electronic health record systems, according to the IHE affinity model, HL7 standards, local standards on interoperability and security, as well as technical advice provided by AGESIC. It is the outcome of the research done by AGESIC and Systems Integration Laboratory (LINS) on the development and use of the e-Government Platform since 2008, as well as the research done by the team Salud.uy since 2013.

  9. In Situ Generation of ArCu from CuF2 Makes Coupling of Bulky Aryl Silanes Feasible and Highly Efficient.

    PubMed

    delPozo, Juan; Casares, Juan A; Espinet, Pablo

    2016-03-14

    A bimetallic system of Pd/CuF2, catalytic in Pd and stoichiometric in Cu, is very efficient and selective for the coupling of fairly hindered aryl silanes with aryl, anisyl, phenylaldehyde, p-cyanophenyl, p-nitrophenyl, or pyridyl iodides of conventional size. The reaction involves the activation of the silane by Cu(II), followed by disproportionation and transmetalation from the Cu(I)(aryl) to Pd(II), upon which coupling takes place. Cu(III) formed during disproportionation is reduced to Cu(I)(aryl) by excess aryl silane, so that the CuF2 system is fully converted into Cu(I)(aryl) and used in the coupling. Moreover, no extra source of fluoride is needed. Interesting size selectivity towards coupling is found in competitive reactions of hindered aryl silanes. Easily accessible [PdCl2 (IDM)(AsPh3)] (IDM = 1,3-dimethylimidazol-2-ylidene) is by far the best catalyst, and the isolated products are essentially free from As or Pd (<1 ppm). The mechanistic aspects of the process have been experimentally examined and discussed.

  10. TERENA eScience PKI

    NASA Astrophysics Data System (ADS)

    Sova, Milan

    Several National Research and Education Networks associated in TERENA have joined their efforts to build a shared PKI able to serve potentially millions of users from their constituency. The TCS eScience Personal CA takes advantage of national identity federations to facilitate user identity vetting and enrollment procedures. The system uses identity management systems (IdMS) at participating institutions to perform the functions of registration authorities. The certificate enrollment application acts as a SAML Service Provider relying on information provided by IdMS performing as SAML Identity Providers (IdP). When applying for a personal certificate, users authenticate at their home IdP using credentials they normally use to access local services. The IdP controls the certificate issuance process by releasing SAML attributes specifying the user's eligibility for the service and the information to be included in the certificate such as the user's name and email address. The TCS eScience Personal CA is part of the TERENA Certificate Service that uses a commercial PKI provider. Outsourcing the actual CA machinery to a specialized company results in professional-level services such as CRL and OCSP management. The paper describes the legal, organizational and technical aspects of the TCS eScience PKI.

  11. TWRSview system requirements specification

    SciTech Connect

    Caldwell, J.A.; Lee, A.K.

    1995-12-01

    This document provides the system requirements specification for the TWRSview software system. The TWRSview software system is being developed to integrate electronic data supporting the development of the TWRS technical baseline

  12. Multivariable Control Systems

    DTIC Science & Technology

    1968-01-01

    one). Examples abound of systems with numerous controlled variables, and the modern tendency is toward ever greater utilization of systems and plants of this kind. We call them multivariable control systems (MCS).

  13. Autonomic Nervous System Disorders

    MedlinePlus

    Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart ... breathing and swallowing Erectile dysfunction in men Autonomic nervous system disorders can occur alone or as the result ...

  14. Manned systems technology discipline

    NASA Technical Reports Server (NTRS)

    Bretoi, Remus

    1990-01-01

    Viewgraphs on manned systems technology discipline for Space Station Freedom are presented. Topics covered include: crew-systems interfaces and interactions; crew training; on-board systems maintenance and support; habitability and environment; and computational human factors.

  15. Air cushion landing system

    NASA Technical Reports Server (NTRS)

    Boghami, K. M.; Captain, K. M.; Fish, R. B.

    1978-01-01

    Static and dynamic performance of air cushion landing system is simulated in computer program that treats four primary ACLS subsystems: fan, feeding system, trunk, and cushion. Configuration of systems is sufficiently general to represent variety of practical designs.

  16. Wind energy systems

    NASA Technical Reports Server (NTRS)

    Stewart, H. J.

    1978-01-01

    A discussion on wind energy systems involved with the DOE wind energy program is presented. Some of the problems associated with wind energy systems are discussed. The cost, efficiency, and structural design of wind energy systems are analyzed.

  17. Lungs and Respiratory System

    MedlinePlus

    ... Your 1- to 2-Year-Old Lungs and Respiratory System KidsHealth > For Parents > Lungs and Respiratory System Print ... ll have taken at least 600 million breaths. Respiratory System Basics All of this breathing couldn't happen ...

  18. The Trinity System

    SciTech Connect

    Archer, Billy Joe; Vigil, Benny Manuel

    2015-01-13

    This paper describes the Trinity system, the first ASC Advanced Technology System (ATS-1). We describe the Trinity procurement timeline, the ASC computing strategy, the Trinity specific mission needs, and the Trinity system specifications.

  19. Lungs and Respiratory System

    MedlinePlus

    ... Your 1- to 2-Year-Old Lungs and Respiratory System KidsHealth > For Parents > Lungs and Respiratory System A ... ll have taken at least 600 million breaths. Respiratory System Basics All of this breathing couldn't happen ...

  20. Evaluating a Portfolio System.

    ERIC Educational Resources Information Center

    Smit, David W.

    1990-01-01

    Contributes to the knowledge of portfolio systems for writing evaluation by sharing evaluative procedures and their results. Reports on the results of a survey of students evaluated using a portfolio system. Finds that students preferred the portfolio system. (RS)

  1. Antiskid braking system

    NASA Technical Reports Server (NTRS)

    Pazdera, J. S.

    1974-01-01

    Published report describes analytical development and simulation of braking system. System prevents wheels from skidding when brakes are applied, significantly reducing stopping distance. Report also presents computer simulation study on system as applied to aircraft.

  2. Digestive System (For Teens)

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Digestive System KidsHealth > For Teens > Digestive System A A A ... out of the body as feces. About the Digestive System Every morsel of food we eat has to ...

  3. Immune System Quiz

    MedlinePlus

    ... Room? What Happens in the Operating Room? Quiz: Immune System KidsHealth > For Kids > Quiz: Immune System A A A How much do you know about your immune system? Find out by taking this quiz! About KidsHealth ...

  4. Systems interface biology

    PubMed Central

    Doyle, Francis J; Stelling, Jörg

    2006-01-01

    The field of systems biology has attracted the attention of biologists, engineers, mathematicians, physicists, chemists and others in an endeavour to create systems-level understanding of complex biological networks. In particular, systems engineering methods are finding unique opportunities in characterizing the rich behaviour exhibited by biological systems. In the same manner, these new classes of biological problems are motivating novel developments in theoretical systems approaches. Hence, the interface between systems and biology is of mutual benefit to both disciplines. PMID:16971329

  5. System status display information

    NASA Technical Reports Server (NTRS)

    Summers, L. G.; Erickson, J. B.

    1984-01-01

    The system Status Display is an electronic display system which provides the flight crew with enhanced capabilities for monitoring and managing aircraft systems. Guidelines for the design of the electronic system displays were established. The technical approach involved the application of a system engineering approach to the design of candidate displays and the evaluation of a Hernative concepts by part-task simulation. The system engineering and selection of candidate displays are covered.

  6. Propulsion Systems Panel deliberations

    NASA Technical Reports Server (NTRS)

    Bianca, Carmelo J.; Miner, Robert; Johnston, Lawrence M.; Bruce, R.; Dennies, Daniel P.; Dickenson, W.; Dreshfield, Robert; Karakulko, Walt; Mcgaw, Mike; Munafo, Paul M.

    1993-01-01

    The Propulsion Systems Panel was established because of the specialized nature of many of the materials and structures technology issues related to propulsion systems. This panel was co-chaired by Carmelo Bianca, MSFC, and Bob Miner, LeRC. Because of the diverse range of missions anticipated for the Space Transportation program, three distinct propulsion system types were identified in the workshop planning process: liquid propulsion systems, solid propulsion systems and nuclear electric/nuclear thermal propulsion systems.

  7. Systems interface biology.

    PubMed

    Doyle, Francis J; Stelling, Jörg

    2006-10-22

    The field of systems biology has attracted the attention of biologists, engineers, mathematicians, physicists, chemists and others in an endeavour to create systems-level understanding of complex biological networks. In particular, systems engineering methods are finding unique opportunities in characterizing the rich behaviour exhibited by biological systems. In the same manner, these new classes of biological problems are motivating novel developments in theoretical systems approaches. Hence, the interface between systems and biology is of mutual benefit to both disciplines.

  8. The LSST: A System of Systems

    NASA Astrophysics Data System (ADS)

    Claver, Chuck F.; Dubois-Felsmann, G. P.; Delgado, F.; Hascall, P.; Horn, D.; Marshall, S.; Nordby, M.; Schalk, T. L.; Schumacher, G.; Sebag, J.; LSST Project Team

    2010-01-01

    The LSST is a complete observing system that acquires and archives images, processes and analyzes them, and publishes reduced images and catalogs of sources and objects. The LSST will operate over a ten year period producing a survey of 20,000 square degrees over the entire southern sky in 6 filters (ugrizy) with each field having been visited several hundred times enabling a wide spectrum of science from fast transients to exploration of dark matter and dark energy. The LSST itself is a complex system of systems consisting of the 8.4m three mirror telescope, a 3.2 billion pixel camera, and a peta-scale data management system. The LSST project uses a Model Based Systems Engineering (MBSE) methodology to ensure an integrated approach to system design and rigorous definition of system interfaces and specifications. The MBSE methodology is applied through modeling of the LSST's systems with the System Modeling Language (SysML). The SysML modeling recursively establishes the threefold relationship between requirements, logical & physical functional decomposition and definition, and system and component behavior at successively deeper levels of abstraction and detail. The MBSE approach is applied throughout all stages of the project from design, to validation and verification, though to commissioning.

  9. Perceptions of Prostate Cancer Screening Controversy and Informed Decision Making: Implications for Development of a Targeted Decision Aid for Unaffected Male First-Degree Relatives

    PubMed Central

    Gwede, Clement K.; Davis, Stacy N.; Wilson, Shaenelle; Patel, Mitul; Vadaparampil, Susan T.; Meade, Cathy D.; Rivers, Brian M.; Yu, Daohai; Torres-Roca, Javier; Heysek, Randy; Spiess, Philippe E.; Pow-Sang, Julio; Jacobsen, Paul

    2014-01-01

    Purpose First-degree relatives (FDRs) of prostate cancer (PC) patients should consider multiple concurrent personal risk factors when engaging in informed decision making (IDM) about PC screening. This study assessed perceptions of IDM recommendations and risk-appropriate strategies for IDM among FDRs of varied race/ethnicity. Design A cross-sectional, qualitative Setting Study setting was a cancer center in southwest Florida. Participants The study comprised 44 participants (24 PC patients and 20 unaffected FDRs). Method Focus groups and individual interviews were conducted and analyzed using content analysis and constant comparison methods. Results Patients and FDRs found the PC screening debate and IDM recommendations to be complex and counterintuitive. They overwhelmingly believed screening saves lives and does not have associated harms. There was a strongly expressed need to improve communication between patients and FDRs. A single decision aid that addresses the needs of all FDRs, rather than separating by race/ethnicity, was recommended as sufficient by study participants. These perspectives guided the development of an innovative decision aid that deconstructs the screening controversy and IDM processes into simpler concepts and provides step-by-step strategies for FDRs to engage in IDM. Conclusion Implementing IDM among FDRs is challenging because the IDM paradigm departs from historical messages promoting routine screening. These contradictions should be recognized and addressed for men to participate effectively in IDM. A randomized pilot study evaluating outcomes of the resulting decision aid is underway. PMID:24968183

  10. Lightside Atmospheric Revitalization System

    NASA Technical Reports Server (NTRS)

    Colling, A. K.; Cushman, R. J.; Hultman, M. M.; Nason, J. R.

    1980-01-01

    The system was studied as a replacement to the present baseline LiOH system for extended duration shuttle missions. The system consists of three subsystems: a solid amine water desorbed regenerable carbon dioxide removal system, a water vapor electrolysis oxygen generating system, and a Sabatier reactor carbon dioxide reduction system. The system is designed for use on a solar powered shuttle vehicle. The majority of the system's power requirements are utilized on the Sun side of each orbit, when solar power is available.

  11. Control system design method

    DOEpatents

    Wilson, David G [Tijeras, NM; Robinett, III, Rush D.

    2012-02-21

    A control system design method and concomitant control system comprising representing a physical apparatus to be controlled as a Hamiltonian system, determining elements of the Hamiltonian system representation which are power generators, power dissipators, and power storage devices, analyzing stability and performance of the Hamiltonian system based on the results of the determining step and determining necessary and sufficient conditions for stability of the Hamiltonian system, creating a stable control system based on the results of the analyzing step, and employing the resulting control system to control the physical apparatus.

  12. Umbra's system representation.

    SciTech Connect

    McDonald, Michael James

    2005-07-01

    This document describes the Umbra System representation. Umbra System representation, initially developed in the spring of 2003, is implemented in Incr/Tcl using concepts borrowed from Carnegie Mellon University's Architecture Description Language (ADL) called Acme. In the spring of 2004 through January 2005, System was converted to Umbra 4, extended slightly, and adopted as the underlying software system for a variety of Umbra applications that support Complex Systems Engineering (CSE) and Complex Adaptive Systems Engineering (CASE). System is now a standard part Of Umbra 4. While Umbra 4 also includes an XML parser for System, the XML parser and Schema are not described in this document.

  13. Integrated Systems Health Management for Intelligent Systems

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Melcher, Kevin

    2011-01-01

    The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. It is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this paper, concepts, procedures, and approaches are presented as a foundation for implementing an intelligent systems ]relevant ISHM capability. The capability stresses integration of DIaK from all elements of a system. Both ground-based (remote) and on-board ISHM capabilities are compared and contrasted. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

  14. Epilogue: Systems Approaches and Systems Practice

    NASA Astrophysics Data System (ADS)

    Reynolds, Martin; Holwell, Sue

    Each of the five systems approaches discussed in this volume: system dynamics (SD), the viable systems model (VSM), strategic options development and analysis (SODA), soft systems methodology (SSM) and critical systems heuristics (CSH) has a pedigree. Not in the sense of the sometimes absurd spectacle of animals paraded at dog shows. Rather, their pedigree derives from their systems foundations, their capacity to evolve and their flexibility in use. None of the five approaches has developed out of use in restricted and controlled contexts of either low or high levels of complicatedness. Neither has any one of them evolved as a consequence of being applied only to situations with either presumed stakeholder agreement on purpose, or courteous disagreement amongst stakeholders, or stakeholder coercion. The compilation is not a celebration of abstract ‘methodologies', but of theoretically robust approaches that have a genuine pedigree in practice.

  15. Systems engineering for very large systems

    NASA Technical Reports Server (NTRS)

    Lewkowicz, Paul E.

    1993-01-01

    Very large integrated systems have always posed special problems for engineers. Whether they are power generation systems, computer networks or space vehicles, whenever there are multiple interfaces, complex technologies or just demanding customers, the challenges are unique. 'Systems engineering' has evolved as a discipline in order to meet these challenges by providing a structured, top-down design and development methodology for the engineer. This paper attempts to define the general class of problems requiring the complete systems engineering treatment and to show how systems engineering can be utilized to improve customer satisfaction and profit ability. Specifically, this work will focus on a design methodology for the largest of systems, not necessarily in terms of physical size, but in terms of complexity and interconnectivity.

  16. Expert system requirements for power system restoration

    SciTech Connect

    Adibi, M.M. ); Kafka, R.J. ); Milanicz, D.P. )

    1994-08-01

    This paper is one of series presented on behalf of the System Operation Subcommittee with the intent of focusing industry attention on power system restoration. Expert systems are being considered for restoring bulk power supplies. In general, there are three restoration periods following a major power disturbance: establishment of initial sources of power, re-integration of a skeleton of the bulk power supply, and minimization of the unserved loads. Expert systems together with analytical tools have the potential of addressing the restoration procedures over these three periods. This paper describes the expert system requirements from the point of view of the practicing power engineers with emphasis placed on the initial power sources and requirements. The paper draws on the previous reports by the Power System Restoration Working Group.

  17. INSENS sensor system

    SciTech Connect

    Myers, D.W.; Baker, J.; Benzel, D.M.; Fuess, D.A.

    1993-09-29

    This paper describes an unattended ground sensor system that has been developed for the immigration and Naturalization Service (INS). The system, known as INSENS, was developed at the Lawrence Livermore National Laboratory for use by the United States Border Patrol. This system assists in the detection of illegal entry of aliens and contraband (illegal drugs, etc.) into the United States along its land borders. Key to the system is its flexible modular design which allows future software and hardware enhancements to the system without altering the fundamental architecture of the system. Elements of the system include a sensor system capable of processing signals from multiple directional probes, a repeater system, and a handheld monitor system. Seismic, passive infrared (PIR), and magnetic probes are currently supported. The design of the INSENS system elements and their performance are described.

  18. Novel central nervous system drug delivery systems.

    PubMed

    Stockwell, Jocelyn; Abdi, Nabiha; Lu, Xiaofan; Maheshwari, Oshin; Taghibiglou, Changiz

    2014-05-01

    For decades, biomedical and pharmaceutical researchers have worked to devise new and more effective therapeutics to treat diseases affecting the central nervous system. The blood-brain barrier effectively protects the brain, but poses a profound challenge to drug delivery across this barrier. Many traditional drugs cannot cross the blood-brain barrier in appreciable concentrations, with less than 1% of most drugs reaching the central nervous system, leading to a lack of available treatments for many central nervous system diseases, such as stroke, neurodegenerative disorders, and brain tumors. Due to the ineffective nature of most treatments for central nervous system disorders, the development of novel drug delivery systems is an area of great interest and active research. Multiple novel strategies show promise for effective central nervous system drug delivery, giving potential for more effective and safer therapies in the future. This review outlines several novel drug delivery techniques, including intranasal drug delivery, nanoparticles, drug modifications, convection-enhanced infusion, and ultrasound-mediated drug delivery. It also assesses possible clinical applications, limitations, and examples of current clinical and preclinical research for each of these drug delivery approaches. Improved central nervous system drug delivery is extremely important and will allow for improved treatment of central nervous system diseases, causing improved therapies for those who are affected by central nervous system diseases.

  19. Immune System as a Sensory System

    PubMed Central

    Dozmorov, Igor M.; Dresser, D.

    2010-01-01

    As suggested by the well-known gestalt concept the immune system can be regarded as an integrated complex system, the functioning of which cannot be fully characterized by the behavior of its constituent elements. Similar approaches to the immune system in particular and sensory systems in general allows one to discern similarities and differences in the process of distinguishing informative patterns in an otherwise random background, thus initiating an appropriate and adequate response. This may lead to a new interpretation of difficulties in the comprehension of some immunological phenomena. PMID:21686066

  20. Hot Spot Removal System: System description

    SciTech Connect

    1997-09-01

    Hazardous wastes contaminated with radionuclides, chemicals, and explosives exist across the Department of Energy complex and need to be remediated due to environmental concerns. Currently, an opportunity is being developed to dramatically reduce remediation costs and to assist in the acceleration of schedules associated with these wastes by deploying a Hot Spot Removal System. Removing the hot spot from the waste site will remove risk driver(s) and enable another, more cost effective process/option/remedial alternative (i.e., capping) to be applied to the remainder of the site. The Hot Spot Removal System consists of a suite of technologies that will be utilized to locate and remove source terms. Components of the system can also be used in a variety of other cleanup activities. This Hot Spot Removal System Description document presents technologies that were considered for possible inclusion in the Hot Spot Removal System, technologies made available to the Hot Spot Removal System, industrial interest in the Hot Spot Removal System`s subsystems, the schedule required for the Hot Spot Removal System, the evaluation of the relevant technologies, and the recommendations for equipment and technologies as stated in the Plan section.

  1. An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma

    PubMed Central

    Gossage, Lucy; Pires, Douglas E. V.; Olivera-Nappa, Álvaro; Asenjo, Juan; Bycroft, Mark; Blundell, Tom L.; Eisen, Tim

    2014-01-01

    Mutations in the von Hippel–Lindau (VHL) gene are pathogenic in VHL disease, congenital polycythaemia and clear cell renal carcinoma (ccRCC). pVHL forms a ternary complex with elongin C and elongin B, critical for pVHL stability and function, which interacts with Cullin-2 and RING-box protein 1 to target hypoxia-inducible factor for polyubiquitination and proteasomal degradation. We describe a comprehensive database of missense VHL mutations linked to experimental and clinical data. We use predictions from in silico tools to link the functional effects of missense VHL mutations to phenotype. The risk of ccRCC in VHL disease is linked to the degree of destabilization resulting from missense mutations. An optimized binary classification system (symphony), which integrates predictions from five in silico methods, can predict the risk of ccRCC associated with VHL missense mutations with high sensitivity and specificity. We use symphony to generate predictions for risk of ccRCC for all possible VHL missense mutations and present these predictions, in association with clinical and experimental data, in a publically available, searchable web server. PMID:24969085

  2. An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.

    PubMed

    Gossage, Lucy; Pires, Douglas E V; Olivera-Nappa, Álvaro; Asenjo, Juan; Bycroft, Mark; Blundell, Tom L; Eisen, Tim

    2014-11-15

    Mutations in the von Hippel-Lindau (VHL) gene are pathogenic in VHL disease, congenital polycythaemia and clear cell renal carcinoma (ccRCC). pVHL forms a ternary complex with elongin C and elongin B, critical for pVHL stability and function, which interacts with Cullin-2 and RING-box protein 1 to target hypoxia-inducible factor for polyubiquitination and proteasomal degradation. We describe a comprehensive database of missense VHL mutations linked to experimental and clinical data. We use predictions from in silico tools to link the functional effects of missense VHL mutations to phenotype. The risk of ccRCC in VHL disease is linked to the degree of destabilization resulting from missense mutations. An optimized binary classification system (symphony), which integrates predictions from five in silico methods, can predict the risk of ccRCC associated with VHL missense mutations with high sensitivity and specificity. We use symphony to generate predictions for risk of ccRCC for all possible VHL missense mutations and present these predictions, in association with clinical and experimental data, in a publically available, searchable web server.

  3. Nonscanning confocal ranging system

    NASA Astrophysics Data System (ADS)

    Sun, P. C.; Arons, E.

    1995-03-01

    We demonstrate a nonscanning confocal ranging system based on spatially incoherent interferometry. Such a system has significant advantages over the conventional confocal imaging system and other interferometric systems. We develop the theory in terms of coherence cells and demonstrate the equivalence of our method to the conventional confocal methods. Experimental results are also provided.

  4. System Engineering Fundamentals

    DTIC Science & Technology

    2001-01-01

    currently valid OMB control number. 1. REPORT DATE JAN 2001 2. REPORT TYPE 3. DATES COVERED 00-00-2001 to 00-00-2001 4. TITLE AND SUBTITLE System...73 PART 3. SYSTEM ANALYSIS AND CONTROL Chapter 9. Work Breakdown Structure...divided into four parts: Introduction; Systems Engineering Process; Systems Analysis and Control ; and Planning, Organizing, and Managing. The first part

  5. Microsphere insulation systems

    NASA Technical Reports Server (NTRS)

    Allen, Mark S. (Inventor); Willen, Gary S. (Inventor); Mohling, Robert A. (Inventor)

    2005-01-01

    A new insulation system is provided that contains microspheres. This insulation system can be used to provide insulated panels and clamshells, and to insulate annular spaces around objects used to transfer, store, or transport cryogens and other temperature-sensitive materials. This insulation system provides better performance with reduced maintenance than current insulation systems.

  6. Medical imaging systems

    DOEpatents

    Frangioni, John V

    2013-06-25

    A medical imaging system provides simultaneous rendering of visible light and diagnostic or functional images. The system may be portable, and may include adapters for connecting various light sources and cameras in open surgical environments or laparascopic or endoscopic environments. A user interface provides control over the functionality of the integrated imaging system. In one embodiment, the system provides a tool for surgical pathology.

  7. Vehicle tracking systems

    SciTech Connect

    Schwalm, R.W.

    1987-01-01

    Several systems have been developed to accomplish vehicle location. The systems consist of three types: Dead Reckoning, Satellite, and LORAN C. If the information is to be sent back to a central location, some type of radiocommunication system is needed. One can use the existing voice radio or add a radio system just for transmitting the data.

  8. Intelligent inspection system

    NASA Astrophysics Data System (ADS)

    May, Jeniece; Dale, Ken; Holloway, Mike; Gaby, Willard

    1997-01-01

    The intelligent inspection system is an advanced controller and analysis system for dimensional measuring machines dedicated to measuring surface of revolution mechanical parts. IIS was developed by the Lockheed Martin Energy Systems, Inc. Oak Ridge Y-12 plant because no commercial product was available to replace the obsolete computing systems on these important machines.

  9. Integrated library systems.

    PubMed Central

    Goldstein, C M

    1983-01-01

    The development of integrated library systems is discussed. The four major discussion points are (1) initial efforts; (2) network resources; (3) minicomputer-based systems; and (4) beyond library automation. Four existing systems are cited as examples of current systems. PMID:6354321

  10. Noncooperative rendezvous radar system

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A fire control radar system was developed, assembled, and modified. The baseline system and modified angle tracking system are described along with the performance characteristics of the baseline and modified systems. Proposed changes to provide additional techniques for radar evaluation are presented along with flight test data.

  11. Universal Index System

    NASA Technical Reports Server (NTRS)

    Kelley, Steve; Roussopoulos, Nick; Sellis, Timos; Wallace, Sarah

    1993-01-01

    The Universal Index System (UIS) is an index management system that uses a uniform interface to solve the heterogeneity problem among database management systems. UIS provides an easy-to-use common interface to access all underlying data, but also allows different underlying database management systems, storage representations, and access methods.

  12. Broad Bandwidth Telecommunications Systems.

    ERIC Educational Resources Information Center

    Sodolski, John

    Broad bandwidth transmission systems have been around for years. They include microwave, assorted cable systems, and recently, satellites. With the exception of some privately owned systems, broadband services have been furnished by the common carriers. Recently, a new element has been added--Cable Antenna Television (CATV) distribution systems.…

  13. Computer Center: CIBE Systems.

    ERIC Educational Resources Information Center

    Crovello, Theodore J.

    1982-01-01

    Differentiates between computer systems and Computers in Biological Education (CIBE) systems (computer system intended for use in biological education). Describes several CIBE stand alone systems: single-user microcomputer; single-user microcomputer/video-disc; multiuser microcomputers; multiuser maxicomputer; and local and long distance computer…

  14. Cogeneration power systems

    NASA Technical Reports Server (NTRS)

    Davis, H. S.

    1978-01-01

    Cogeneration is defined as the combination of electrical generation and process heat for more efficient use of fuel. Comparisons of energy utilization in conventional electric power plants and cogeneration electric power plants are presented. Characteristics of various cogeneration systems are also presented. Systems are analyzed for use in utility systems and industrial systems. Economic and cost analysis are reviewed.

  15. Theory of reliable systems

    NASA Technical Reports Server (NTRS)

    Meyer, J. F.

    1975-01-01

    An attempt was made to refine the current notion of system reliability by identifying and investigating attributes of a system which are important to reliability considerations. Techniques which facilitate analysis of system reliability are included. Special attention was given to fault tolerance, diagnosability, and reconfigurability characteristics of systems.

  16. Program (systems) engineering

    NASA Technical Reports Server (NTRS)

    Baroff, Lynn E.; Easter, Robert W.; Pomphrey, Richard B.

    2004-01-01

    Program Systems Engineering applies the principles of Systems Engineering at the program level. Space programs are composed of interrelated elements which can include collections of projects, advanced technologies, information systems, etc. Some program elements are outside traditional engineering's physical systems, such as education and public outreach, public relations, resource flow, and interactions within the political environments.

  17. Analyzing HVAC piping systems

    SciTech Connect

    Smith, W.W. )

    1993-10-01

    This article describes requirements and considerations for a software tool for analyzing both the hydraulic and heat transfer characteristics of a HVAC system to help in selecting systems components and predicting their performance. The topics of the article include analysis of installed system evolution, selection and analysis of pumps and valves, heat transfer in heating and cooling coils, and capacity to handle large systems.

  18. Image display system 511

    NASA Technical Reports Server (NTRS)

    Gross, M.

    1981-01-01

    The experience of the Idaho Department of Water Resources Remote Sensing Unit in bringing on line their System 511 is described. The system 511 is run on a PDP minicomputer. The minimum system hardware configuration is an 11/34 with a minimum core of 128 K word, 10 megabytes of direct access disk and a floating point processor. The required software configuration is an RSX 11M V 3.2 operating system with a FORTRAN IV plus compiler. The structure of System 511 is a series of hierarchical modular software units. Problems occurring during the systems installation are discussed, and the system operating and error detection capabilities and documentation evaluated.

  19. Lightning mapping system

    NASA Technical Reports Server (NTRS)

    Lennon, C.; Maier, L.

    1991-01-01

    A Lightning Detection and Ranging (LDAR) System is being implemented at KSC in Florida. The first operational use is expected in the late summer of 1991. The system is designed to map the location of in-cloud and cloud-to-ground lightning based on the time of arrival (TOA) of electromagnetic radiation. The system detects very high frequency (VHF) radiation and designed to map the volumetric extent of lightning. The system implements two independent antenna arrays to provide a fast data quality check, as necessary for a real-time warning system. The system performance goals and a comparison with a similar system implemented in the mid-1970's is made.

  20. What is systems engineering?

    SciTech Connect

    Bahill, A.T.

    1995-08-01

    Systems Engineering is an interdisciplinary process that ensures that the customers` needs are satisfied throughout a system`s entire life cycle. This process includes: understanding customer needs; stating the problem; specifying requirements; defining performance and cost measures, prescribing tests, validating requirements, conducting design reviews, exploring alternative concepts, sensitivity analyses, functional decomposition, system design, designing and managing interfaces, system integration, total system test, configuration management, risk management, reliability analysis; total quality management; project management; and documentation. Material for this paper was gathered from senior Systems Engineers at Sandia National Laboratories.

  1. Memory effects in microscopic traffic models and wide scattering in flow-density data.

    PubMed

    Treiber, Martin; Helbing, Dirk

    2003-10-01

    By means of microscopic simulations we show that noninstantaneous adaptation of the driving behavior to the traffic situation together with the conventional method to measure flow-density data provides a possible explanation for the observed inverse-lambda shape and the wide scattering of flow-density data in "synchronized" congested traffic. We model a memory effect in the response of drivers to the traffic situation for a wide class of car-following models by introducing an additional dynamical variable (the "subjective level of service") describing the adaptation of drivers to the surrounding traffic situation during the past few minutes and couple this internal state to parameters of the underlying model that are related to the driving style. For illustration, we use the intelligent-driver model (IDM) as the underlying model, characterize the level of service solely by the velocity, and couple the internal variable to the IDM parameter "time gap" to model an increase of the time gap in congested traffic ("frustration effect"), which is supported by single-vehicle data. We simulate open systems with a bottleneck and obtain flow-density data by implementing "virtual detectors." The shape, relative size, and apparent "stochasticity" of the region of the scattered data points agree nearly quantitatively with empirical data. Wide scattering is even observed for identical vehicles, although the proposed model is a time-continuous, deterministic, single-lane car-following model with a unique fundamental diagram.

  2. Synthesis, characterization and drug release properties of 3D chitosan/clinoptilolite biocomposite cryogels.

    PubMed

    Dinu, Maria Valentina; Cocarta, Ana Irina; Dragan, Ecaterina Stela

    2016-11-20

    Three-dimensional (3D) biocomposites based on chitosan (CS) and clinoptilolite (CPL) were prepared by cryogelation and their potential application as drug carriers was investigated. Variation of CPL content from 0 to 33wt.% allowed the formation of biocomposites with heterogeneous morphologies consisting of randomly distributed pores. The further increase of CPL content led to ordered porous architectures where parallel pore channels were observed. The CPL content had a strong influence on water uptake, as well as on the cumulative release of diclofenac sodium (DS) and indomethacin (IDM). It was demonstrated that the drug delivery preferentially takes place in phosphate buffer saline (pH 7.4) in comparison to simulated gastric fluid (pH 1.2), where only a reduced drug release was observed. The drug release mechanism dominating these systems is described as a pseudo-Fickian diffusion, but it changes to non-Fickian release when 33wt.% of CPL was entrapped into the CS matrix or when IDM was loaded into biocomposites.

  3. Model-driven approach to data collection and reporting for quality improvement

    PubMed Central

    Curcin, Vasa; Woodcock, Thomas; Poots, Alan J.; Majeed, Azeem; Bell, Derek

    2014-01-01

    Continuous data collection and analysis have been shown essential to achieving improvement in healthcare. However, the data required for local improvement initiatives are often not readily available from hospital Electronic Health Record (EHR) systems or not routinely collected. Furthermore, improvement teams are often restricted in time and funding thus requiring inexpensive and rapid tools to support their work. Hence, the informatics challenge in healthcare local improvement initiatives consists of providing a mechanism for rapid modelling of the local domain by non-informatics experts, including performance metric definitions, and grounded in established improvement techniques. We investigate the feasibility of a model-driven software approach to address this challenge, whereby an improvement model designed by a team is used to automatically generate required electronic data collection instruments and reporting tools. To that goal, we have designed a generic Improvement Data Model (IDM) to capture the data items and quality measures relevant to the project, and constructed Web Improvement Support in Healthcare (WISH), a prototype tool that takes user-generated IDM models and creates a data schema, data collection web interfaces, and a set of live reports, based on Statistical Process Control (SPC) for use by improvement teams. The software has been successfully used in over 50 improvement projects, with more than 700 users. We present in detail the experiences of one of those initiatives, Chronic Obstructive Pulmonary Disease project in Northwest London hospitals. The specific challenges of improvement in healthcare are analysed and the benefits and limitations of the approach are discussed. PMID:24874182

  4. Model-driven approach to data collection and reporting for quality improvement.

    PubMed

    Curcin, Vasa; Woodcock, Thomas; Poots, Alan J; Majeed, Azeem; Bell, Derek

    2014-12-01

    Continuous data collection and analysis have been shown essential to achieving improvement in healthcare. However, the data required for local improvement initiatives are often not readily available from hospital Electronic Health Record (EHR) systems or not routinely collected. Furthermore, improvement teams are often restricted in time and funding thus requiring inexpensive and rapid tools to support their work. Hence, the informatics challenge in healthcare local improvement initiatives consists of providing a mechanism for rapid modelling of the local domain by non-informatics experts, including performance metric definitions, and grounded in established improvement techniques. We investigate the feasibility of a model-driven software approach to address this challenge, whereby an improvement model designed by a team is used to automatically generate required electronic data collection instruments and reporting tools. To that goal, we have designed a generic Improvement Data Model (IDM) to capture the data items and quality measures relevant to the project, and constructed Web Improvement Support in Healthcare (WISH), a prototype tool that takes user-generated IDM models and creates a data schema, data collection web interfaces, and a set of live reports, based on Statistical Process Control (SPC) for use by improvement teams. The software has been successfully used in over 50 improvement projects, with more than 700 users. We present in detail the experiences of one of those initiatives, Chronic Obstructive Pulmonary Disease project in Northwest London hospitals. The specific challenges of improvement in healthcare are analysed and the benefits and limitations of the approach are discussed.

  5. The Shuttle inertial system

    NASA Technical Reports Server (NTRS)

    Swingle, W. L.; Kang, Y.

    1982-01-01

    The Space Shuttle inertial system is built around a sensor assembly called the inertial measurement unit (IMU). The system includes a redundant set of three structurally integrated IMU's that operate in conjunction with parallel strung data system computers to provide precise attitude and velocity information to user system functions. The inertial system is actually a separate subsystem function integrated into the overall avionics system. Software resident in the system computers is the final link in the inertial system. The inertial software is comprised of two major sets, including a subsystem operating program (SOP) called the IMU SOP and redundancy management. Attention is given to system applications, systems performance, attitude sensitivities, the IMU platform, IMU thermal management, aspects of IMU calibration, and Shuttle program experience.

  6. Performance, Performance System, and High Performance System

    ERIC Educational Resources Information Center

    Jang, Hwan Young

    2009-01-01

    This article proposes needed transitions in the field of human performance technology. The following three transitions are discussed: transitioning from training to performance, transitioning from performance to performance system, and transitioning from learning organization to high performance system. A proposed framework that comprises…

  7. Advanced information processing system: Local system services

    NASA Technical Reports Server (NTRS)

    Burkhardt, Laura; Alger, Linda; Whittredge, Roy; Stasiowski, Peter

    1989-01-01

    The Advanced Information Processing System (AIPS) is a multi-computer architecture composed of hardware and software building blocks that can be configured to meet a broad range of application requirements. The hardware building blocks are fault-tolerant, general-purpose computers, fault-and damage-tolerant networks (both computer and input/output), and interfaces between the networks and the computers. The software building blocks are the major software functions: local system services, input/output, system services, inter-computer system services, and the system manager. The foundation of the local system services is an operating system with the functions required for a traditional real-time multi-tasking computer, such as task scheduling, inter-task communication, memory management, interrupt handling, and time maintenance. Resting on this foundation are the redundancy management functions necessary in a redundant computer and the status reporting functions required for an operator interface. The functional requirements, functional design and detailed specifications for all the local system services are documented.

  8. ENVIRONMENTAL SYSTEMS MANAGEMENT AND SUSTAINABLE SYSTEMS THEORY

    EPA Science Inventory

    Environmental Systems Management is the management of environmental problems at the systems level fully accounting for the multi-dimensional nature of the environment. This includes socio-economic dimensions as well as the usual physical and life science aspects. This is importa...

  9. Efficient Evaluation System for Learning Management Systems

    ERIC Educational Resources Information Center

    Cavus, Nadire

    2009-01-01

    A learning management system (LMS) provides the platform for web-based learning environment by enabling the management, delivery, tracking of learning, testing, communication, registration process and scheduling. There are many LMS systems on the market that can be obtained for free or through payment. It has now become an important task to choose…

  10. EPICS system: system structure and user interface

    SciTech Connect

    West, R.E.; Bartlett, J.F.; Bobbitt, J.S.; Lahey, T.E.; Kramper, B.J.; MacKinnon, B.A.

    1984-02-01

    This paper present the user's view of and the general organization of the EPICS control system at Fermilab. Various subsystems of the EPICS control system are discussed. These include the user command language, software protection, the device database, remote computer interfaces, and several application utilities. This paper is related to two other papers on EPICS: an overview paper and a detailed implementation paper.

  11. Formal System Verification for Trustworthy Embedded Systems

    DTIC Science & Technology

    2011-04-19

    Koscher, Alexei Czeskis, Franziska Roesner, Shwetak Patel, Tadayoshi Kohno, Stephen Checkoway, Damon McCoy, Brian Kantor, Danny Anderson, Hovav...security analysis of a commercial real-time operating system kernel. In David S. Hardin , editor, Design and Verification of Microprocessor Systems for High

  12. Rf systems for RHIC

    SciTech Connect

    Rose, J.; Brodowski, J.; Connolly, R.; Deng, D.P.; Kwiatkowski, S.; Pirkl, W.; Ratti, A.

    1995-05-01

    The RHIC rf systems must capture the injected beam, accelerate it through transition to top energy, shorten the bunches prior to rebucketing, and store the beam for 10 hours in the presence of strong intra-beam scattering. These different functions are met by three independent systems. An accelerating system at 26.7 Mhz (h = 342), a storage system at 196.1 MHz (h = 2508), and a wideband system for the damping of injection efforts.

  13. Robotics and expert systems

    SciTech Connect

    Not Available

    1986-01-01

    This volume contains papers presented at ROBEXS' 86, the Second Annual Workshop on Robotics and Expert Systems. Many diverse perspectives on automation problems, and on the merging of robotics and expert systems technology with conventional systems, are contained in this book. The contents include: Integrated Expert Systems Applications; Expert Systems Theory and Applications, Robotics, Intelligent Control, CAD/CAE/CAM, AI Tools, Human Factors, and intelligent Interfaces.

  14. Fluid infusion system

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Performance testing carried out in the development of the prototype zero-g fluid infusion system is described and summarized. Engineering tests were performed in the course of development, both on the original breadboard device and on the prototype system. This testing was aimed at establishing baseline system performance parameters and facilitating improvements. Acceptance testing was then performed on the prototype system to verify functional performance. Acceptance testing included a demonstration of the fluid infusion system on a laboratory animal.

  15. Photovoltaic systems and applications

    SciTech Connect

    Not Available

    1982-01-01

    Abstracts are given of presentations given at a project review meeting held at Albuquerque, NM. The proceedings cover the past accomplishments and current activities of the Photovoltaic Systems Research, Balance-of-System Technology Development and System Application Experiments Projects at Sandia National Laboratories. The status of intermediate system application experiments and residential system analysis is emphasized. Some discussion of the future of the Photovoltaic Program in general, and the Sandia projects in particular is also presented.

  16. Automated Pilot Advisory System

    NASA Technical Reports Server (NTRS)

    Parks, J. L., Jr.; Haidt, J. G.

    1981-01-01

    An Automated Pilot Advisory System (APAS) was developed and operationally tested to demonstrate the concept that low cost automated systems can provide air traffic and aviation weather advisory information at high density uncontrolled airports. The system was designed to enhance the see and be seen rule of flight, and pilots who used the system preferred it over the self announcement system presently used at uncontrolled airports.

  17. Evolvable synthetic neural system

    NASA Technical Reports Server (NTRS)

    Curtis, Steven A. (Inventor)

    2009-01-01

    An evolvable synthetic neural system includes an evolvable neural interface operably coupled to at least one neural basis function. Each neural basis function includes an evolvable neural interface operably coupled to a heuristic neural system to perform high-level functions and an autonomic neural system to perform low-level functions. In some embodiments, the evolvable synthetic neural system is operably coupled to one or more evolvable synthetic neural systems in a hierarchy.

  18. Data Acquisition Systems

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Technology developed during a joint research program with Langley and Kinetic Systems Corporation led to Kinetic Systems' production of a high speed Computer Automated Measurement and Control (CAMAC) data acquisition system. The study, which involved the use of CAMAC equipment applied to flight simulation, significantly improved the company's technical capability and produced new applications. With Digital Equipment Corporation, Kinetic Systems is marketing the system to government and private companies for flight simulation, fusion research, turbine testing, steelmaking, etc.

  19. Solar photovoltaic systems

    NASA Technical Reports Server (NTRS)

    Forney, R. G.

    1978-01-01

    The Department of Energy's photovoltaic program is outlined. The main objective of the program is the development of low cost reliable terrestrial photovoltaic systems. A second objective is to foster widespread use of the system in residential, industrial and commercial application. The system is reviewed by examining each component; silicon solar cell, silicon solar cell modules, advanced development modules and power systems. Cost and applications of the system are discussed.

  20. On evolutionary systems.

    PubMed

    Alvarez de Lorenzana, J M; Ward, L M

    1987-01-01

    This paper develops a metatheoretical framework for understanding evolutionary systems (systems that develop in ways that increase their own variety). The framework addresses shortcomings seen in other popular systems theories. It concerns both living and nonliving systems, and proposes a metahierarchy of hierarchical systems. Thus, it potentially addresses systems at all descriptive levels. We restrict our definition of system to that of a core system whose parts have a different ontological status than the system, and characterize the core system in terms of five global properties: minimal length interval, minimal time interval, system cycle, total receptive capacity, and system potential. We propose two principles through the interaction of which evolutionary systems develop. The Principle of Combinatorial Expansion describes how a core system realizes its developmental potential through a process of progressive differentiation of the single primal state up to a limit stage. The Principle of Generative Condensation describes how the components of the last stage of combinatorial expansion condense and become the environment for and components of new, enriched systems. The early evolution of the Universe after the "big bang" is discussed in light of these ideas as an example of the application of the framework.

  1. A System of Systems Approach to the EU Energy System

    NASA Astrophysics Data System (ADS)

    Jess, Tom; Madani, Kaveh; Mahlooji, Maral; Ristic, Bora

    2016-04-01

    Around the world, measures to prevent dangerous climate change are being adopted and may change energy systems fundamentally. The European Union (EU) is committed to reducing greenhouse gas emission by 20% by 2020 and by 80-95% by 2050. In order to achieve this, EU member states aim to increase the share of renewables in the energy mix to 20% by 2020. This commitment comes as part of a series of other aims, principles, and policies to reform the EU's energy system. Cost-efficiency in the emissions reductions measures as well as strategic goals under the Resource Efficient Europe flagship initiative which would include a more prudent approach to other natural resources such as water and land. Using the "System of Systems Approach", as from Hadian and Madani (2015), energy sources' Relative Aggregate Footprints (RAF) in the EU are evaluated. RAF aggregates across four criteria: carbon footprint, water footprint, land footprint, and economic cost. The four criteria are weighted by resource availability across the EU and for each Member State. This provides an evaluation of the overall resource use efficiency of the EU's energy portfolio and gives insight into the differences in the desirability of energy sources across Member States. Broadly, nuclear, onshore wind, and geothermal are most desirable under equal criteria weights and EU average weighting introduces only small changes in the relative performance of only few technologies. The member state specific weightings show that most countries have similar energy technology preferences. However, the UK deviates most strongly from the average, with an even stronger preference for nuclear and coal. Sweden, Malta and Finland also deviate from the typical preferences indicating the complexity in play in reforming the EU energy system. Reference Hadian S, Madani K (2015) A System of Systems Approach to Energy Sustainability Assessment: Are All Renewables Really Green? Ecological Indicators, 52, 194-206.

  2. Intelligent systems technology infrastructure for integrated systems

    NASA Technical Reports Server (NTRS)

    Lum, Henry

    1991-01-01

    A system infrastructure must be properly designed and integrated from the conceptual development phase to accommodate evolutionary intelligent technologies. Several technology development activities were identified that may have application to rendezvous and capture systems. Optical correlators in conjunction with fuzzy logic control might be used for the identification, tracking, and capture of either cooperative or non-cooperative targets without the intensive computational requirements associated with vision processing. A hybrid digital/analog system was developed and tested with a robotic arm. An aircraft refueling application demonstration is planned within two years. Initially this demonstration will be ground based with a follow-on air based demonstration. System dependability measurement and modeling techniques are being developed for fault management applications. This involves usage of incremental solution/evaluation techniques and modularized systems to facilitate reuse and to take advantage of natural partitions in system models. Though not yet commercially available and currently subject to accuracy limitations, technology is being developed to perform optical matrix operations to enhance computational speed. Optical terrain recognition using camera image sequencing processed with optical correlators is being developed to determine position and velocity in support of lander guidance. The system is planned for testing in conjunction with Dryden Flight Research Facility. Advanced architecture technology is defining open architecture design constraints, test bed concepts (processors, multiple hardware/software and multi-dimensional user support, knowledge/tool sharing infrastructure), and software engineering interface issues.

  3. Modeling Power Systems as Complex Adaptive Systems

    SciTech Connect

    Chassin, David P.; Malard, Joel M.; Posse, Christian; Gangopadhyaya, Asim; Lu, Ning; Katipamula, Srinivas; Mallow, J V.

    2004-12-30

    Physical analogs have shown considerable promise for understanding the behavior of complex adaptive systems, including macroeconomics, biological systems, social networks, and electric power markets. Many of today's most challenging technical and policy questions can be reduced to a distributed economic control problem. Indeed, economically based control of large-scale systems is founded on the conjecture that the price-based regulation (e.g., auctions, markets) results in an optimal allocation of resources and emergent optimal system control. This report explores the state-of-the-art physical analogs for understanding the behavior of some econophysical systems and deriving stable and robust control strategies for using them. We review and discuss applications of some analytic methods based on a thermodynamic metaphor, according to which the interplay between system entropy and conservation laws gives rise to intuitive and governing global properties of complex systems that cannot be otherwise understood. We apply these methods to the question of how power markets can be expected to behave under a variety of conditions.

  4. Alkaline etch system qualification

    SciTech Connect

    Goldammer, S.E.; Pemberton, S.E.; Tucker, D.R.

    1997-04-01

    Based on the data from this qualification activity, the Atotech etch system, even with minimum characterization, was capable of etching production printed circuit products as good as those from the Chemcut system. Further characterization of the Atotech system will improve its etching capability. In addition to the improved etch quality expected from further characterization, the Atotech etch system has additional features that help reduce waste and provide for better consistency in the etching process. The programmable logic controller and computer will allow operators to operate the system manually or from pre-established recipes. The evidence and capabilities of the Atotech system made it as good as or better than the Chemcut system for etching WR products. The Printed Wiring Board Engineering Department recommended that the Atotech system be released for production. In December 1995, the Atotech system was formerly qualified for production.

  5. NASA systems engineering handbook

    NASA Astrophysics Data System (ADS)

    Shishko, Robert; Aster, Robert; Chamberlain, Robert G.; McDuffee, Patrick; Pieniazek, Les; Rowell, Tom; Bain, Beth; Cox, Renee I.; Mooz, Harold; Polaski, Lou

    1995-06-01

    This handbook brings the fundamental concepts and techniques of systems engineering to NASA personnel in a way that recognizes the nature of NASA systems and environment. It is intended to accompany formal NASA training courses on systems engineering and project management when appropriate, and is designed to be a top-level overview. The concepts were drawn from NASA field center handbooks, NMI's/NHB's, the work of the NASA-wide Systems Engineering Working Group and the Systems Engineering Process Improvement Task team, several non-NASA textbooks and guides, and material from independent systems engineering courses taught to NASA personnel. Five core chapters cover systems engineering fundamentals, the NASA Project Cycle, management issues in systems engineering, systems analysis and modeling, and specialty engineering integration. It is not intended as a directive.

  6. Rover waste assay system

    SciTech Connect

    Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J.

    1997-11-01

    The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched {sup 235}U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for {sup 137}Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs.

  7. NASA Systems Engineering Handbook

    NASA Technical Reports Server (NTRS)

    Shishko, Robert; Aster, Robert; Chamberlain, Robert G.; Mcduffee, Patrick; Pieniazek, Les; Rowell, Tom; Bain, Beth; Cox, Renee I.; Mooz, Harold; Polaski, Lou

    1995-01-01

    This handbook brings the fundamental concepts and techniques of systems engineering to NASA personnel in a way that recognizes the nature of NASA systems and environment. It is intended to accompany formal NASA training courses on systems engineering and project management when appropriate, and is designed to be a top-level overview. The concepts were drawn from NASA field center handbooks, NMI's/NHB's, the work of the NASA-wide Systems Engineering Working Group and the Systems Engineering Process Improvement Task team, several non-NASA textbooks and guides, and material from independent systems engineering courses taught to NASA personnel. Five core chapters cover systems engineering fundamentals, the NASA Project Cycle, management issues in systems engineering, systems analysis and modeling, and specialty engineering integration. It is not intended as a directive. Superseded by: NASA/SP-2007-6105 Rev 1 (20080008301).

  8. Enhanced nurse call systems.

    PubMed

    2001-04-01

    This Evaluation focuses on high-end computerized nurse call systems--what we call enhanced systems. These are highly flexible systems that incorporate microprocessor and communications technologies to expand the capabilities of the nurse call function. Enhanced systems, which vary in configuration from one installation to the next, typically consist of a basic system that provides standard nurse call functionality and a combination of additional enhancements that provide the added functionality the facility desires. In this study, we examine the features that distinguish enhanced nurse call systems from nonenhanced systems, focusing on their application and benefit to healthcare facilities. We evaluated seven systems to determine how well they help (1) improve patient care, as well as increase satisfaction with the care provided, and (2) improve caregiver efficiency, as well as increase satisfaction with the work environment. We found that all systems meet these objectives, but not all systems perform equally well for all implementations. Our ratings will help facilities identify those systems that offer the most effective features for their intended use. The study also includes a Technology Management Guide to help readers (1) determine whether they'll benefit from the capabilities offered by enhanced systems and (2) target a system for purchase and equip the system for optimum performance and cost-effective operation.

  9. Open systems storage platforms

    NASA Technical Reports Server (NTRS)

    Collins, Kirby

    1992-01-01

    The building blocks for an open storage system includes a system platform, a selection of storage devices and interfaces, system software, and storage applications CONVEX storage systems are based on the DS Series Data Server systems. These systems are a variant of the C3200 supercomputer with expanded I/O capabilities. These systems support a variety of medium and high speed interfaces to networks and peripherals. System software is provided in the form of ConvexOS, a POSIX compliant derivative of 4.3BSD UNIX. Storage applications include products such as UNITREE and EMASS. With the DS Series of storage systems, Convex has developed a set of products which provide open system solutions for storage management applications. The systems are highly modular, assembled from off the shelf components with industry standard interfaces. The C Series system architecture provides a stable base, with the performance and reliability of a general purpose platform. This combination of a proven system architecture with a variety of choices in peripherals and application software allows wide flexibility in configurations, and delivers the benefits of open systems to the mass storage world.

  10. Space shuttle avionics system

    NASA Technical Reports Server (NTRS)

    Hanaway, John F.; Moorehead, Robert W.

    1989-01-01

    The Space Shuttle avionics system, which was conceived in the early 1970's and became operational in the 1980's represents a significant advancement of avionics system technology in the areas of systems and redundacy management, digital data base technology, flight software, flight control integration, digital fly-by-wire technology, crew display interface, and operational concepts. The origins and the evolution of the system are traced; the requirements, the constraints, and other factors which led to the final configuration are outlined; and the functional operation of the system is described. An overall system block diagram is included.

  11. Introducing Systems Approaches

    NASA Astrophysics Data System (ADS)

    Reynolds, Martin; Holwell, Sue

    Systems Approaches to Managing Change brings together five systems approaches to managing complex issues, each having a proven track record of over 25 years. The five approaches are: System Dynamics (SD) developed originally in the late 1950s by Jay Forrester Viable Systems Model (VSM) developed originally in the late 1960s by Stafford Beer Strategic Options Development and Analysis (SODA: with cognitive mapping) developed originally in the 1970s by Colin Eden Soft Systems Methodology (SSM) developed originally in the 1970s by Peter Checkland Critical Systems Heuristics (CSH) developed originally in the late 1970s by Werner Ulrich

  12. Flash evaporator systems test

    NASA Technical Reports Server (NTRS)

    Dietz, J. B.

    1976-01-01

    A flash evaporator heat rejection system representative of that proposed for the space shuttle orbiter underwent extensive system testing at the NASA Johnson Space Center (JSC) to determine its operational suitability and to establish system performance/operational characteristics for use in the shuttle system. During the tests the evaporator system demonstrated its suitability to meet the shuttle requirements by: (1) efficient operation with 90 to 95% water evaporation efficiency, (2) control of outlet temperature to 40 + or - 2 F for partial heat load operation, (3) stability of control system for rapid changes in Freon inlet temperature, and (4) repeated dormant-to-active device operation without any startup procedures.

  13. Data Acquisition Systems

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In the mid-1980s, Kinetic Systems and Langley Research Center determined that high speed CAMAC (Computer Automated Measurement and Control) data acquisition systems could significantly improve Langley's ARTS (Advanced Real Time Simulation) system. The ARTS system supports flight simulation R&D, and the CAMAC equipment allowed 32 high performance simulators to be controlled by centrally located host computers. This technology broadened Kinetic Systems' capabilities and led to several commercial applications. One of them is General Atomics' fusion research program. Kinetic Systems equipment allows tokamak data to be acquired four to 15 times more rapidly. Ford Motor company uses the same technology to control and monitor transmission testing facilities.

  14. MLS: Airplane system modeling

    NASA Technical Reports Server (NTRS)

    Thompson, A. D.; Stapleton, B. P.; Walen, D. B.; Rieder, P. F.; Moss, D. G.

    1981-01-01

    Analysis, modeling, and simulations were conducted as part of a multiyear investigation of the more important airplane-system-related items of the microwave landing system (MLS). Particular emphasis was placed upon the airplane RF system, including the antenna radiation distribution, the cabling options from the antenna to the receiver, and the overall impact of the airborne system gains and losses upon the direct-path signal structure. In addition, effort was expended toward determining the impact of the MLS upon the airplane flight management system and developing the initial stages of a fast-time MLS automatic control system simulation model. Results ot these studies are presented.

  15. Cooperating systems: Layered MAS

    NASA Technical Reports Server (NTRS)

    Rochowiak, Daniel

    1990-01-01

    Distributed intelligent systems can be distinguished by the models that they use. The model developed focuses on layered multiagent system conceived of as a bureaucracy in which a distributed data base serves as a central means of communication. The various generic bureaus of such a system is described and a basic vocabulary for such systems is presented. In presenting the bureaus and vocabularies, special attention is given to the sorts of reasonings that are appropriate. A bureaucratic model has a hierarchy of master system and work group that organizes E agents and B agents. The master system provides the administrative services and support facilities for the work groups.

  16. Continuous system modeling

    NASA Technical Reports Server (NTRS)

    Cellier, Francois E.

    1991-01-01

    A comprehensive and systematic introduction is presented for the concepts associated with 'modeling', involving the transition from a physical system down to an abstract description of that system in the form of a set of differential and/or difference equations, and basing its treatment of modeling on the mathematics of dynamical systems. Attention is given to the principles of passive electrical circuit modeling, planar mechanical systems modeling, hierarchical modular modeling of continuous systems, and bond-graph modeling. Also discussed are modeling in equilibrium thermodynamics, population dynamics, and system dynamics, inductive reasoning, artificial neural networks, and automated model synthesis.

  17. Fundamentals of systems ergonomics.

    PubMed

    Wilson, John R

    2012-01-01

    Ergonomics/human factors is, above anything else, a systems discipline applying a systems philosophy and systems approaches. Many things are labeled as "systems X" in today's world, and this paper specifies just what attributes and notions define ergonomics/human factors in systems terms. These are concern for context, acknowledgement of interactions and complexity, a holistic approach, recognition of emergence and embedding of the professional effort involved within organization systems. These five notions are illustrated with examples from a large body of work on rail human factors.

  18. Business System Planning Project System Requirements Specification

    SciTech Connect

    NELSON, R.E.

    2000-09-08

    The purpose of the Business Systems Planning Project System Requirements Specification (SRS) is to provide the outline and contents of the requirements for the CH2M HILL Hanford Group, Inc. (CHG) integrated business and technical information systems. The SRS will translate proposed objectives into the statement of the functions that are to be performed and data and information flows that they require. The requirements gathering methodology will use (1) facilitated group requirement sessions; (2) individual interviews; (3) surveys; and (4) document reviews. The requirements will be verified and validated through coordination of the technical requirement team and CHG Managers. The SRS document used the content and format specified in Lockheed Martin Services, Inc. Organization Standard Software Practices in conjunction with the Institute of Electrical and Electronics Engineers Standard 8340-1984 for Systems Requirements Documents.

  19. NASA's SPICE System Models the Solar System

    NASA Technical Reports Server (NTRS)

    Acton, Charles

    1996-01-01

    SPICE is NASA's multimission, multidiscipline information system for assembling, distributing, archiving, and accessing space science geometry and related data used by scientists and engineers for mission design and mission evaluation, detailed observation planning, mission operations, and science data analysis.

  20. Power system interface and umbilical system study

    NASA Technical Reports Server (NTRS)

    1980-01-01

    System requirements and basic design criteria were defined for berthing or docking a payload to the 25 kW power module which will provide electrical power and attitude control, cooling, data transfer, and communication services to free-flying and Orbiter sortie payloads. The selected umbilical system concept consists of four assemblies and command and display equipment to be installed at the Orbiter payload specialist station: (1) a movable platen assembly which is attached to the power system with EVA operable devices; (2) a slave platen assembly which is attached to the payload with EVA operable devices; (3) a fixed secondary platen permanently installed in the power system; and (4) a fixed secondary platen permanently installed on the payload. Operating modes and sequences are described.

  1. Unmanned Aerial System, New System Manning Prediction

    DTIC Science & Technology

    2006-01-01

    during the same mission, the area under surveillance is subject to a chemical attack during a period of inclement weather, say low-level fog or rain...these potential fog -of-war situations occur that systems design, particularly manning, must be able to cope with the imposed load. This concept is...of some of the data, that is, because of the dispersion in manning values for the five systems chosen, a rank-based regression would provide a more

  2. Combat Systems Department Employee Recognition System

    DTIC Science & Technology

    1996-08-01

    the individual’s view of positive reinforcement . Include them in discussions. Ask for their opinions. 4 NSWCDD/MP-96/137 SECTION 3 INSTRUCTIONS 3.1...PROVIDES POSITIVE REINFORCEMENT . THE EASIER IT IS TO DO, THE MORE LIKELY IT IS TO GET DONE. N-DEPARTMENT EMPLOYEE RECOGNITION SYSTEM PRI NCI PLES THERE ARE...INDIVIDUAL’S VIEW OF POSITIVE REINFORCEMENT . ASK THEM I Papa .18Iv 15 N-DEPARTMENT EMPLOYEE RECOGNITION SYSTEM * OUTLINE A. TASK FORCE MEMBERSHIP

  3. Integrated Systems Health Management for Intelligent Systems

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Melcher, Kevin

    2011-01-01

    The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. Management implies storage, distribution, sharing, maintenance, processing, reasoning, and presentation. ISHM is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this chapter, concepts, procedures, and approaches are presented as a foundation for implementing an ISHM capability relevant to intelligent systems. The capability stresses integration of DIaK from all elements of a system, emphasizing an advance toward an on-board, autonomous capability. Both ground-based and on-board ISHM capabilities are addressed. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

  4. System and method for creating expert systems

    NASA Technical Reports Server (NTRS)

    Hughes, Peter M. (Inventor); Luczak, Edward C. (Inventor)

    1998-01-01

    A system and method provides for the creation of a highly graphical expert system without the need for programming in code. An expert system is created by initially building a data interface, defining appropriate Mission, User-Defined, Inferred, and externally-generated GenSAA (EGG) data variables whose data values will be updated and input into the expert system. Next, rules of the expert system are created by building appropriate conditions of the rules which must be satisfied and then by building appropriate actions of rules which are to be executed upon corresponding conditions being satisfied. Finally, an appropriate user interface is built which can be highly graphical in nature and which can include appropriate message display and/or modification of display characteristics of a graphical display object, to visually alert a user of the expert system of varying data values, upon conditions of a created rule being satisfied. The data interface building, rule building, and user interface building are done in an efficient manner and can be created without the need for programming in code.

  5. Absorption heat pump system

    DOEpatents

    Grossman, G.

    1982-06-16

    The efficiency of an absorption heat pump system is improved by conducting liquid from a second stage evaporator thereof to an auxiliary heat exchanger positioned downstream of a primary heat exchanger in the desorber of the system.

  6. Intensive care alarm system

    NASA Technical Reports Server (NTRS)

    Christensen, J. L.; Herbert, A. L.

    1973-01-01

    Inductive loop has been added to commercially available call system fitted with earphone receiver. System transmits high frequency signals to nurse's receiver to announce patient's need for help without disturbing others.

  7. Data-Retrieval System

    NASA Technical Reports Server (NTRS)

    Lawrence, P. R.

    1982-01-01

    NASA Graphics and Display System (NGDS) helps solve problem of data retrieval for management. Since NGDS is interactive online system, user controls display content and format, and has capability of always working with latest version of his data.

  8. Semiotic labelled deductive systems

    SciTech Connect

    Nossum, R.T.

    1996-12-31

    We review the class of Semiotic Models put forward by Pospelov, as well as the Labelled Deductive Systems developed by Gabbay, and construct an embedding of Semiotic Models into Labelled Deductive Systems.

  9. Septic Systems Case Studies

    EPA Pesticide Factsheets

    A collection of septic systems case studies to help community planners, elected officials, health department staff, state officials, and interested citizens explore alternatives for managing their decentralized wastewater treatment systems.

  10. Central nervous system

    MedlinePlus

    The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

  11. Information retrieval system

    NASA Technical Reports Server (NTRS)

    Berg, R. F.; Holcomb, J. E.; Kelroy, E. A.; Levine, D. A.; Mee, C., III

    1970-01-01

    Generalized information storage and retrieval system capable of generating and maintaining a file, gathering statistics, sorting output, and generating final reports for output is reviewed. File generation and file maintenance programs written for the system are general purpose routines.

  12. Male Reproductive System

    MedlinePlus

    ... gamete, the egg or ovum, meet in the female's reproductive system to create a baby. Both the male and female reproductive systems are essential for reproduction. Humans pass certain characteristics ...

  13. Modular optical detector system

    DOEpatents

    Horn, Brent A.; Renzi, Ronald F.

    2006-02-14

    A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the emitted fluorescence. Because the system is capable of accurately detecting and measuring picomolar concentrations it is ideally suited for use with microchemical analysis systems generally and capillary chromatographic systems in particular. By employing a modular design, the detector system provides both the ability to replace various elements of the detector system without requiring extensive realignment or recalibration of the components as well as minimal user interaction with the system. In addition, the modular concept provides for the use and addition of a wide variety of components, including optical elements (lenses and filters), light sources, and detection means, to fit particular needs.

  14. Test processing system (SEE)

    NASA Technical Reports Server (NTRS)

    Gaulene, P.

    1986-01-01

    The SEE data processing system, developed in 1985, manages and process test results. General information is provided on the SEE system: objectives, characteristics, basic principles, general organization, and operation. Full documentation is accessible by computer using the HELP SEE command.

  15. Double Degenerate Binary Systems

    SciTech Connect

    Yakut, K.

    2011-09-21

    In this study, angular momentum loss via gravitational radiation in double degenerate binary (DDB)systems (NS + NS, NS + WD, WD + WD, and AM CVn) is studied. Energy loss by gravitational waves has been estimated for each type of systems.

  16. Instructional Systems: Which One?

    ERIC Educational Resources Information Center

    Lee, A. Maughan

    1970-01-01

    Discusses the mystical aura attached to the notion of a systems approach to instruction, briefly reviews some of the instructional systems which have been advanced, and suggests a method for successful implementation of the process. (LS)

  17. OPTIMUM SYSTEMS CONTROL,

    DTIC Science & Technology

    Variational calculus and continuous optimal control, (4) The maximum principle and Hamilton Jacobi theory, (5) Optimum systems control examples, (6...Discrete variational calculus and the discrete maximum principle, (7) Optimum control of distributed parameter systems, (8) Optimum state estimation in

  18. Pneumonia - weakened immune system

    MedlinePlus

    ... treatments to remove fluid and mucus from the respiratory system are often needed. Outlook (Prognosis) Factors that may ... immunocompromised host Images Pneumococci organism Lungs The lungs Respiratory system References Donnelly JP, Blijlevens NMA, van der Velden ...

  19. Avian respiratory system disorders

    USGS Publications Warehouse

    Olsen, G.H.

    1989-01-01

    Diagnosing and treating respiratory diseases in avian species requires a basic knowledge about the anatomy and physiology of this system in birds. Differences between mammalian and avian respiratory system function, diagnosis, and treatment are highlighted.

  20. Advanced dive monitoring system.

    PubMed

    Sternberger, W I; Goemmer, S A

    1999-01-01

    The US Navy supports deep diving operations with a variety of mixed-gas life support systems. A systems engineering study was conducted for the Naval Experimental Dive Unit (Panama City, FL) to develop a concept design for an advanced dive monitoring system. The monitoring system is intended primarily to enhance diver safety and secondarily to support diving medicine research. Distinct monitoring categories of diver physiology, life support system, and environment are integrated in the monitoring system. A system concept is proposed that accommodates real-time and quantitative measurements, noninvasive physiological monitoring, and a flexible and expandable implementation architecture. Human factors and ergonomic design considerations have been emphasized to assure that there is no impact on the diver's primary mission. The Navy has accepted the resultant system requirements and the basic design concept. A number of monitoring components have been implemented and successfully support deep diving operations.

  1. Immune System and Disorders

    MedlinePlus

    Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It ... t, to find and destroy them. If your immune system cannot do its job, the results can be ...

  2. System status display evaluation

    NASA Technical Reports Server (NTRS)

    Summers, Leland G.

    1988-01-01

    The System Status Display is an electronic display system which provides the crew with an enhanced capability for monitoring and managing the aircraft systems. A flight simulation in a fixed base cockpit simulator was used to evaluate alternative design concepts for this display system. The alternative concepts included pictorial versus alphanumeric text formats, multifunction versus dedicated controls, and integration of the procedures with the system status information versus paper checklists. Twelve pilots manually flew approach patterns with the different concepts. System malfunctions occurred which required the pilots to respond to the alert by reconfiguring the system. The pictorial display, the multifunction control interfaces collocated with the system display, and the procedures integrated with the status information all had shorter event processing times and lower subjective workloads.

  3. Absorption heat pump system

    DOEpatents

    Grossman, Gershon

    1984-01-01

    The efficiency of an absorption heat pump system is improved by conducting liquid from a second stage evaporator thereof to an auxiliary heat exchanger positioned downstream of a primary heat exchanger in the desorber of the system.

  4. Female Reproductive System

    MedlinePlus

    ... Ectopic Pregnancy A Week-by-Week Pregnancy Calendar Male Reproductive System Five Things Girls Want to Know About Periods ... Coping With Common Period Problems All About Menstruation Male Reproductive System Everything You Wanted to Know About Puberty Polycystic ...

  5. Renewable Energy Tracking Systems

    EPA Pesticide Factsheets

    Renewable energy generation ownership can be accounted through tracking systems. Tracking systems are highly automated, contain specific information about each MWh, and are accessible over the internet to market participants.

  6. Leasing Residential PV Systems

    SciTech Connect

    Rutberg, Michael; Bouza, Antonio

    2013-11-01

    The article discusses the adoption, consequences and current market status of the leasing of residential photovoltaic systems. It addresses attributed energy savings and market potential of residential system leasing.

  7. Henry Ford Health Systems

    Cancer.gov

    Henry Ford Health Systems evolved from a hospital into a system delivering care to 2.5 million patients and includes the Cancer Epidemiology, Prevention and Control Program, which focuses on epidemiologic and public health aspects of cancer.

  8. INL Autonomous Navigation System

    SciTech Connect

    2005-03-30

    The INL Autonomous Navigation System provides instructions for autonomously navigating a robot. The system permits high-speed autonomous navigation including obstacle avoidance, waypoing navigation and path planning in both indoor and outdoor environments.

  9. Drinking Water Distribution Systems

    EPA Pesticide Factsheets

    Learn about an overview of drinking water distribution systems, the factors that degrade water quality in the distribution system, assessments of risk, future research about these risks, and how to reduce cross-connection control risk.

  10. Silver recovery system data

    SciTech Connect

    Boulineau, B.

    1991-08-26

    In August of 1990 the Savannah River Site Photography Group began testing on a different type of silver recovery system. This paper describes the baseline study and the different phases of installation and testing of the system.

  11. Designing automatic resupply systems.

    PubMed

    Harding, M L

    1999-02-01

    This article outlines the process for designing and implementing autoresupply systems. The planning process includes determination of goals and appropriate participation. Different types of autoresupply mechanisms include kanban, breadman, consignment, systems contracts, and direct shipping from an MRP schedule.

  12. Validation of multiprocessor systems

    NASA Technical Reports Server (NTRS)

    Siewiorek, D. P.; Segall, Z.; Kong, T.

    1982-01-01

    Experiments that can be used to validate fault free performance of multiprocessor systems in aerospace systems integrating flight controls and avionics are discussed. Engineering prototypes for two fault tolerant multiprocessors are tested.

  13. Multiplex television transmission system

    NASA Technical Reports Server (NTRS)

    Reed, W. R.

    1967-01-01

    Time-multiplexing system enables several cameras to share a single commercial television transmission channel. This system is useful in industries for visually monitoring several operating areas or instrument panels from a remote location.

  14. Alarm Notification System

    SciTech Connect

    1995-03-12

    AN/EMS, the Alarm Notification Energy Management System, is used to monitor digital sensors in PETC buildings and to notify the safety/security operator by both a video and an audio system when a possibly hazardous condition arises.

  15. Nonsurvivable momentum exchange system

    NASA Technical Reports Server (NTRS)

    Roder, Russell (Inventor); Ahronovich, Eliezer (Inventor); Davis, III, Milton C. (Inventor)

    2007-01-01

    A demiseable momentum exchange system includes a base and a flywheel rotatably supported on the base. The flywheel includes a web portion defining a plurality of web openings and a rim portion. The momentum exchange system further includes a motor for driving the flywheel and a cover for engaging the base to substantially enclose the flywheel. The system may also include components having a melting temperature below 1500 degrees Celsius. The momentum exchange system is configured to demise on reentry.

  16. Propulsion system needs

    NASA Technical Reports Server (NTRS)

    Gunn, Stanley

    1991-01-01

    The needs of the designer of a solid core nuclear rocket engine are discussed. Some of the topics covered include: (1) a flight thrust module/feed system module assembly; (2) a nuclear thermal rocket (NTR), expander cycle, dual T/P; (3) turbopump operating conditions; (4) typical system parameters; (5) growth capability composite fuel elements; (6) a NTR radiation cooled nozzle extension; (7) a NFS-3B Feed System; and (8) a NTR Integrated Pneumatic-Fluidics Control System.

  17. Immersive Visual Programming System

    DTIC Science & Technology

    1995-03-16

    improved virtual programming system. 20 It is another object to provide a virtual programming system that optimally increases a user’s comprehensibility...of program structures. NAVY CASE NO. 75554 It is still another object to provide a virtual programming system that is useful for defining the high...level flow control and data pathways within a program. It is yet another object to provide a virtual programming system that allows for dynamic

  18. Space power systems technology

    NASA Technical Reports Server (NTRS)

    Coulman, George A.

    1994-01-01

    Reported here is a series of studies which examine several potential catalysts and electrodes for some fuel cell systems, some materials for space applications, and mathematical modeling and performance predictions for some solid oxide fuel cells and electrolyzers. The fuel cell systems have a potential for terrestrial applications in addition to solar energy conversion in space applications. Catalysts and electrodes for phosphoric acid fuel cell systems and for polymer electrolyte membrane (PEM) fuel cell and electrolyzer systems were examined.

  19. Linear system theory

    NASA Technical Reports Server (NTRS)

    Callier, Frank M.; Desoer, Charles A.

    1991-01-01

    The aim of this book is to provide a systematic and rigorous access to the main topics of linear state-space system theory in both the continuous-time case and the discrete-time case; and the I/O description of linear systems. The main thrusts of the work are the analysis of system descriptions and derivations of their properties, LQ-optimal control, state feedback and state estimation, and MIMO unity-feedback systems.

  20. Visual Alert System

    NASA Technical Reports Server (NTRS)

    1985-01-01

    A visual alert system resulted from circuitry developed by Applied Cybernetics Systems for Langley as part of a space related telemetry system. James Campman, Applied Cybernetics president, left the company and founded Grace Industries, Inc. to manufacture security devices based on the Langley technology. His visual alert system combines visual and audible alerts for hearing impaired people. The company also manufactures an arson detection device called the electronic nose, and is currently researching additional applications of the NASA technology.

  1. Thermochemical energy systems research

    NASA Astrophysics Data System (ADS)

    Nix, R. G.

    1983-08-01

    Research on Heat-pump thermochemical energy systems and thermochemical reduction of CO2 to CO for open-loop solar energy transport is described. Analysis of the NaOH-H2O heat-pumped system indicted cost effectiveness relative to hot oil solar system with parabolic trough receivers for production of 0.101 MPa saturated steam high-temperature heat-pumped systems are being defined.

  2. Portable Dental System

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Portable dental system provides dental care in isolated communities. System includes a patient's chair and a dentist's stool, an X-ray machine and a power unit, all of which fold into compact packages. A large yellow "pumpkin" is a collapsible compressed air tank. Portable system has been used successfully in South America in out of the way communities with this back-packable system, and in American nursing homes. This product is no longer manufactured.

  3. The DISCUS Hardware System,

    DTIC Science & Technology

    1982-07-01

    it physically impossible for one processor to access another’s local program or workspace. It should be noted that the system - generator should handle...this gateway would be complex and how it would be used and linked to the system generator would also be difficult. Because of this it worth asking...which is by no means trivial to write, identified several faults in the system generator and operating system that would have otherwise been

  4. Intermediate water recovery system

    NASA Technical Reports Server (NTRS)

    Deckman, G.; Anderson, A. R. (Editor)

    1973-01-01

    A water recovery system for collecting, storing, and processing urine, wash water, and humidity condensates from a crew of three aboard a spacecraft is described. The results of a 30-day test performed on a breadboard system are presented. The intermediate water recovery system produced clear, sterile, water with a 96.4 percent recovery rate from the processed urine. Recommendations for improving the system are included.

  5. Goddard Ground System Environment

    NASA Technical Reports Server (NTRS)

    Liu, Ben

    2009-01-01

    This slide presentation reviews the Goddard Mission Services Evolution Center's work in providing the Ground System Infrastructure to allow for standard interfaces, and allow for a mix of heritage and new components. This software has been used by NASA and other Government users. Telemetry and command services are also provided as are mission planning and scheduling systems. Other areas that the presentation covers are work on trending systems, and data management system.

  6. Automated RTOP Management System

    NASA Technical Reports Server (NTRS)

    Hayes, P.

    1984-01-01

    The structure of NASA's Office of Aeronautics and Space Technology electronic information system network from 1983 to 1985 is illustrated. The RTOP automated system takes advantage of existing hardware, software, and expertise, and provides: (1) computerized cover sheet and resources forms; (2) electronic signature and transmission; (3) a data-based information system; (4) graphics; (5) intercenter communications; (6) management information; and (7) text editing. The system is coordinated with Headquarters efforts in codes R,E, and T.

  7. Lithium battery management system

    DOEpatents

    Dougherty, Thomas J [Waukesha, WI

    2012-05-08

    Provided is a system for managing a lithium battery system having a plurality of cells. The battery system comprises a variable-resistance element electrically connected to a cell and located proximate a portion of the cell; and a device for determining, utilizing the variable-resistance element, whether the temperature of the cell has exceeded a predetermined threshold. A method of managing the temperature of a lithium battery system is also included.

  8. Space power systems technology

    NASA Astrophysics Data System (ADS)

    Coulman, George A.

    1994-03-01

    Reported here is a series of studies which examine several potential catalysts and electrodes for some fuel cell systems, some materials for space applications, and mathematical modeling and performance predictions for some solid oxide fuel cells and electrolyzers. The fuel cell systems have a potential for terrestrial applications in addition to solar energy conversion in space applications. Catalysts and electrodes for phosphoric acid fuel cell systems and for polymer electrolyte membrane (PEM) fuel cell and electrolyzer systems were examined.

  9. Space station power system

    NASA Technical Reports Server (NTRS)

    Baraona, Cosmo R.

    1987-01-01

    The major requirements and guidelines that affect the space station configuration and power system are explained. The evolution of the space station power system from the NASA program development-feasibility phase through the current preliminary design phase is described. Several early station concepts are described and linked to the present concept. Trade study selections of photovoltaic system technologies are described in detail. A summary of present solar dynamic and power management and distribution systems is also given.

  10. GRAPS: Graphical Plotting System.

    DTIC Science & Technology

    1985-07-01

    stand-alone unit, but could (with a few modifications) be incorporated into a larger system; e.g., the IGUANA system (ref 3). The GRAPS system...the GRAPS software into another system (e.g., the IGUANA ) could possibly introduce additional requirements. I have simply listed those things...Graphics Utility For Army NEC Automation ( IGUANA ), May 1985. 4. Hewlett-Packard Corp., Interfacing and Programming Manual - HP 7470A Graphics Plotter

  11. Compact Antispin Parachute System

    NASA Technical Reports Server (NTRS)

    Whipple, R. D.

    1985-01-01

    Costs and complexity of parachute system greatly reduced. Rigidtowline parachute system operates in three steps: (1) When aircraft begins to spin, parachute compartment opened up, and parachute unfolds; (2) Parachute deployed and spin terminated; and (3) Parachute released. Advantage of towline system allows use of much smaller parachute, reducing design loads on structural reinforcement. Also, complex pyrotechnic-deployment or jettison systems no longer necessary.

  12. Energy Systems Laboratory Groundbreaking

    SciTech Connect

    Hill, David; Otter, C.L.; Simpson, Mike; Rogers, J.W.

    2011-01-01

    INL recently broke ground for a research facility that will house research programs for bioenergy, advanced battery systems, and new hybrid energy systems that integrate renewable, fossil and nuclear energy sources. Here's video from the groundbreaking ceremony for INL's new Energy Systems Laboratory. You can learn more about CAES research at http://www.facebook.com/idahonationallaboratory.

  13. Solar tracking system

    DOEpatents

    Okandan, Murat; Nielson, Gregory N.

    2016-07-12

    Solar tracking systems, as well as methods of using such solar tracking systems, are disclosed. More particularly, embodiments of the solar tracking systems include lateral supports horizontally positioned between uprights to support photovoltaic modules. The lateral supports may be raised and lowered along the uprights or translated to cause the photovoltaic modules to track the moving sun.

  14. Circulation Systems on Microcomputers.

    ERIC Educational Resources Information Center

    Carlson, Gary

    1984-01-01

    Reports on the use of microcomputers in comprehensive library circulation systems. Topics covered include system requirements (reliability, completeness); determining circulation system needs (saving money, improving service, modernization); limitations of microcomputers (capacity, kinds of data stored, number of stations or terminals); system…

  15. Types of Data Systems

    ERIC Educational Resources Information Center

    Gould, Tate; Nicholas, Amy; Ruggiero, Tony; Blandford, William; Thayer, Sara; Bull, Bruce

    2015-01-01

    There are several types of data systems that support data from Part C/619 programs. Although the system types have similarities, each has its own unique characteristics and purposes. The attributes that make one type of data system a particularly good fit for one data-related need or function can be less desirable for another need or function. In…

  16. Spleen and Lymphatic System

    MedlinePlus

    ... A Week of Healthy Breakfasts Shyness Spleen and Lymphatic System KidsHealth > For Teens > Spleen and Lymphatic System A A A What's in this article? Why ... español El bazo y el sistema linfático The lymphatic system is an extensive drainage network that helps keep ...

  17. Microelectronics bioinstrumentation systems

    NASA Technical Reports Server (NTRS)

    Ko, W. H.

    1977-01-01

    Microelectronic bioinstrumentation systems to be employed in the Cardiovascular Deconditioning Program were developed. Implantable telemetry systems for long-term monitoring of animals on earth were designed to collect physiological data necessary for the understanding of the mechanisms of cardiovascular deconditioning. In-flight instrumentation systems, microelectronic instruments, and RF powering techniques for other life science experiments in the NASA program were studied.

  18. Unified Science - System.

    ERIC Educational Resources Information Center

    Thomson, Barbara S.

    The goals of this curriculum, developed as a summer course for the Young Scholars Program at The Ohio State University-Columbus, are as follows: (1) enable students to develop an understanding of the concept of a system; (2) help students gain an appreciation of the value of systems; (3) develop skills in working with systems; (4) expand skills in…

  19. Control Oriented System Identification

    DTIC Science & Technology

    1993-08-01

    The research goals for this grant were to obtain algorithms for control oriented system identification is to construct dynamical models of systems...and measured information. Algorithms for this type of nonlinear system identification have been given that produce models suitable for gain scheduled

  20. Female Reproductive System

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Female Reproductive System KidsHealth > For Parents > Female Reproductive System A A ... the egg or sperm. continue Parts of the Female Reproductive System Unlike the male, the human female has a ...

  1. MILITARY INFORMATION SYSTEMS,

    DTIC Science & Technology

    upward are usually indications of how effectively the system is developing or operating. The use of computers in information systems tends to increase...computers into information systems must always begin at the lowest level of aggregation in the job hierarchy. Only those information-processing jobs

  2. Rapid response deluge system

    NASA Astrophysics Data System (ADS)

    Mille, J. R.

    1984-08-01

    The development of a rapid response deluge system by the Ammunition Equipment Directorate (AED) for use in suppressing propellant fires during demilitarization shows great promise. Prototype systems have been tested and data acquired on their efficiencies. Present system vs previous generations and lessons learned are discussed.

  3. System Documentation Manual.

    ERIC Educational Resources Information Center

    Semmel, Melvyn I.; Olson, Jerry

    The document is a system documentation manual of the Computer-Assisted Teacher Training System (CATTS) developed by the Center for Innovation in Teaching the Handicapped (Indiana University). CATTS is characterized as a system capable of providing continuous, instantaneous, and/or delayed feedback of relevant teacher-student interaction data to a…

  4. No System? No Software!

    ERIC Educational Resources Information Center

    Conley, Donna

    1989-01-01

    Noting that the computer software cataloging system at the media center of the Washington (Illinois) Center for Continuing Education is essentially a card catalog in notebook form, this article describes aspects of the development and utilization of the system. Major sections describe: (1) software cataloging system terminology; (2) steps for…

  5. FUNDAMENTALS OF TELEVISION SYSTEMS.

    ERIC Educational Resources Information Center

    KESSLER, WILLIAM J.

    DESIGNED FOR A READER WITHOUT SPECIAL TECHNICAL KNOWLEDGE, THIS ILLUSTRATED RESOURCE PAPER EXPLAINS THE COMPONENTS OF A TELEVISION SYSTEM AND RELATES THEM TO THE COMPLETE SYSTEM. SUBJECTS DISCUSSED ARE THE FOLLOWING--STUDIO ORGANIZATION AND COMPATIBLE COLOR TELEVISION PRINCIPLES, WIRED AND RADIO TRANSMISSION SYSTEMS, DIRECT VIEW AND PROJECTION…

  6. System integration report

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  7. IDC System Specification Document.

    SciTech Connect

    Clifford, David J.

    2014-12-01

    This document contains the system specifications derived to satisfy the system requirements found in the IDC System Requirements Document for the IDC Reengineering Phase 2 project. Revisions Version Date Author/Team Revision Description Authorized by V1.0 12/2014 IDC Reengineering Project Team Initial delivery M. Harris

  8. Economical space power systems

    NASA Technical Reports Server (NTRS)

    Burkholder, J. H.

    1980-01-01

    A commercial approach to design and fabrication of an economical space power system is investigated. Cost projections are based on a 2 kW space power system conceptual design taking into consideration the capability for serviceability, constraints of operation in space, and commercial production engineering approaches. A breakdown of the system design, documentation, fabrication, and reliability and quality assurance estimated costs are detailed.

  9. Energy Systems Laboratory Groundbreaking

    ScienceCinema

    Hill, David; Otter, C.L.; Simpson, Mike; Rogers, J.W.

    2016-07-12

    INL recently broke ground for a research facility that will house research programs for bioenergy, advanced battery systems, and new hybrid energy systems that integrate renewable, fossil and nuclear energy sources. Here's video from the groundbreaking ceremony for INL's new Energy Systems Laboratory. You can learn more about CAES research at http://www.facebook.com/idahonationallaboratory.

  10. Neutron radiographic viewing system

    NASA Technical Reports Server (NTRS)

    Leysath, W.; Brown, R. L.

    1972-01-01

    Neutron radiographic viewing system consisting of camera head and control processor is developed for use in nondestructive testing applications. Camera head consists of neutron-sensitive image intensifier system, power supply, and SEC vidicon camera head. Both systems, with their optics, are housed on test mount.

  11. Lungs and Respiratory System

    MedlinePlus

    ... A Week of Healthy Breakfasts Shyness Lungs and Respiratory System KidsHealth > For Teens > Lungs and Respiratory System Print ... didn't breathe, you couldn't live. Lungs & Respiratory System Basics Each day we breathe about 20,000 ...

  12. Immune System Quiz

    MedlinePlus

    ... los dientes Video: Getting an X-ray Quiz: Immune System KidsHealth > For Kids > Quiz: Immune System Print A A A How much do you know about your immune system? Find out by taking this quiz! About KidsHealth ...

  13. Facilities Data System Manual.

    ERIC Educational Resources Information Center

    Acridge, Charles W.; Ford, Tim M.

    The purposes of this manual are to set forth the scope and procedures for the maintenance and operation of the University of California facilities Data System (FDX) and to serve as a reference document for users of the system. FDX is an information system providing planning and management data about the existing physical plant. That is, it…

  14. Personal Food System Mapping

    ERIC Educational Resources Information Center

    Wilsey, David; Dover, Sally

    2014-01-01

    Personal food system mapping is a practical means to engage community participants and educators in individualized and shared learning about food systems, decisions, and behaviors. Moreover, it is a useful approach for introducing the food system concept, which is somewhat abstract. We developed the approach to capture diversity of personal food…

  15. Lungs and Respiratory System

    MedlinePlus

    ... A Week of Healthy Breakfasts Shyness Lungs and Respiratory System KidsHealth > For Teens > Lungs and Respiratory System A ... didn't breathe, you couldn't live. Lungs & Respiratory System Basics Each day we breathe about 20,000 ...

  16. Arkansas Technology Information System.

    ERIC Educational Resources Information Center

    VanBiervliet, Alan; Parette, Howard P., Jr.

    The Arkansas Technology Information System (ARTIS) was developed to fill a significant void in existing systems of technical support to Arkansans with disabilities by creating and maintaining a consumer-responsive statewide system of data storage and retrieval regarding assistive technology and services. ARTIS goals also include establishment of a…

  17. Power system restoration issues

    SciTech Connect

    Adibi, M.M. ); Kafka, R.J. )

    1991-04-01

    This article describes some of the problems encountered in the three phases of power system restoration (PSR). The three phases of PSR are: Planning for restart and reintegration of the bulk power supply; Actions during system degradation for saving and retaining critical sources of power; Restoration when the power system has stabilized at some degraded level.

  18. Polymerase chain reaction system

    DOEpatents

    Benett, William J.; Richards, James B.; Stratton, Paul L.; Hadley, Dean R.; Milanovich, Fred P.; Belgrader, Phil; Meyer, Peter L.

    2004-03-02

    A portable polymerase chain reaction DNA amplification and detection system includes one or more chamber modules. Each module supports a duplex assay of a biological sample. Each module has two parallel interrogation ports with a linear optical system. The system is capable of being handheld.

  19. Male Reproductive System

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Male Reproductive System KidsHealth > For Parents > Male Reproductive System Print A ... understand your son's reproductive health. continue About the Male Reproductive System Most species have two sexes: male and female. ...

  20. Jupiter System Observer

    NASA Technical Reports Server (NTRS)

    Senske, Dave; Prockter, Louise

    2008-01-01

    This slide presentation reviews the scientific philosophy that is guiding the planning behind the Jupiter System Observer (JSO). The JSO would be a long-term platform for studying Jupiter and the complete Jovian system. The goal is to advance the understanding of the fundamental processes of planetary systems, their formation and evolution.

  1. Enterprise Systems Analysis

    DTIC Science & Technology

    2016-03-14

    Systems ...Report No. SERC-2016-TR-103 Copyright © 2016 Stevens Institute of Technology The Systems Engineering Research Center (SERC) is a federally...Stevens Institute of Technology and Systems Engineering Research Center Material is furnished on an “as-is” basis. Stevens Institute of

  2. Astromag data system concept

    NASA Technical Reports Server (NTRS)

    Roos, Darrell; Cheng, Chieh-San; Newsome, Penny; Nath, Nitya

    1989-01-01

    A feasible, top-level data system is defined that could accomplish and support the Astromag Data System functions and interfaces necessary to support the scientific objectives of Astromag. This data system must also be able to function in the environment of the Space Station Freedom Manned Base (SSFMB) and other anticipated NASA elements.

  3. Wastewater Collection Systems.

    PubMed

    Vallabhaneni, Srinivas

    2015-10-01

    This chapter presents a review of the literature published in 2014 on topics relating to wastewater collection systems. It presents advances in noteworthy research and industry experiences selected from major literature sources. This review is divided into the following sections: sewer system planning; sewer condition assessment/rehabilitation; pump stations and system design; operation and maintenance; and regulatory issues/ integrated planning.

  4. Desiccant humidity control system

    NASA Technical Reports Server (NTRS)

    Amazeen, J. (Editor)

    1973-01-01

    A regenerable sorbent system was investigated for controlling the humidity and carbon dioxide concentration of the space shuttle cabin atmosphere. The sorbents considered for water and carbon dioxide removal were silica gel and molecular sieves. Bed optimization and preliminary system design are discussed along with system optimization studies and weight penalites.

  5. Special Education Resource System.

    ERIC Educational Resources Information Center

    Kampert, George J.

    The guide to the Special Education Resource System (SERS) of the Flour Bluff (Texas) school system contains policies and procedures regarding organization, services, and process of the system. Noted is the SERS purpose of providing information and access to appropriate instructional media and materials for special education personnel. Briefly…

  6. The Global Positioning System

    DTIC Science & Technology

    1989-05-01

    Global Positioning System ( GPS ) and current program status are provided. The importance of...the NAVSTAR Global Positioning System (NAVSTAR GPS or GPS ) will have on future weapons employment. The study will: examine why we need a high...Washington, D.C., 24 January, 1984. Malone, Daniel K. GPS /NAVSTAR. Military Review, March 1986. Nepean, Phillip The NAVSTAR Global Positioning System

  7. Information extraction system

    DOEpatents

    Lemmond, Tracy D; Hanley, William G; Guensche, Joseph Wendell; Perry, Nathan C; Nitao, John J; Kidwell, Paul Brandon; Boakye, Kofi Agyeman; Glaser, Ron E; Prenger, Ryan James

    2014-05-13

    An information extraction system and methods of operating the system are provided. In particular, an information extraction system for performing meta-extraction of named entities of people, organizations, and locations as well as relationships and events from text documents are described herein.

  8. Electric system restructuring and system reliability

    NASA Astrophysics Data System (ADS)

    Horiuchi, Catherine Miller

    In 1996 the California legislature passed AB 1890, explicitly defining economic benefits and detailing specific mechanisms for initiating a partial restructuring the state's electric system. Critics have since sought re-regulation and proponents have asked for patience as the new institutions and markets take shape. Other states' electric system restructuring activities have been tempered by real and perceived problems in the California model. This study examines the reduced regulatory controls and new constraints introduced in California's limited restructuring model using utility and regulatory agency records from the 1990's to investigate effects of new institutions and practices on system reliability for the state's five largest public and private utilities. Logit and negative binomial regressions indicate negative impact from the California model of restructuring on system reliability as measured by customer interruptions. Time series analysis of outage data could not predict the wholesale power market collapse and the subsequent rolling blackouts in early 2001; inclusion of near-outage reliability disturbances---load shedding and energy emergencies---provided a measure of forewarning. Analysis of system disruptions, generation capacity and demand, and the role of purchased power challenge conventional wisdom on the causality of Californian's power problems. The quantitative analysis was supplemented by a targeted survey of electric system restructuring participants. Findings suggest each utility and the organization controlling the state's electric grid provided protection from power outages comparable to pre-restructuring operations through 2000; however, this reliability has come at an inflated cost, resulting in reduced system purchases and decreased marginal protection. The historic margin of operating safety has fully eroded, increasing mandatory load shedding and emergency declarations for voluntary and mandatory conservation. Proposed remedies focused

  9. SNS Cryogenic Systems Commissioning

    SciTech Connect

    D. Hatfield; F. Casagrande; I. Campisi; P. Gurd; M. Howell; D. Stout; H. Strong; D. Arenius; J. Creel; K. Dixon; V. Ganni; and P. Knudsen

    2005-08-29

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  10. Benchmarking expert system tools

    NASA Technical Reports Server (NTRS)

    Riley, Gary

    1988-01-01

    As part of its evaluation of new technologies, the Artificial Intelligence Section of the Mission Planning and Analysis Div. at NASA-Johnson has made timing tests of several expert system building tools. Among the production systems tested were Automated Reasoning Tool, several versions of OPS5, and CLIPS (C Language Integrated Production System), an expert system builder developed by the AI section. Also included in the test were a Zetalisp version of the benchmark along with four versions of the benchmark written in Knowledge Engineering Environment, an object oriented, frame based expert system tool. The benchmarks used for testing are studied.

  11. Text Exchange System

    NASA Technical Reports Server (NTRS)

    Snyder, W. V.; Hanson, R. J.

    1986-01-01

    Text Exchange System (TES) exchanges and maintains organized textual information including source code, documentation, data, and listings. System consists of two computer programs and definition of format for information storage. Comprehensive program used to create, read, and maintain TES files. TES developed to meet three goals: First, easy and efficient exchange of programs and other textual data between similar and dissimilar computer systems via magnetic tape. Second, provide transportable management system for textual information. Third, provide common user interface, over wide variety of computing systems, for all activities associated with text exchange.

  12. Superconductor rotor cooling system

    DOEpatents

    Gamble, Bruce B.; Sidi-Yekhlef, Ahmed; Schwall, Robert E.; Driscoll, David I.; Shoykhet, Boris A.

    2004-11-02

    A system for cooling a superconductor device includes a cryocooler located in a stationary reference frame and a closed circulation system external to the cryocooler. The closed circulation system interfaces the stationary reference frame with a rotating reference frame in which the superconductor device is located. A method of cooling a superconductor device includes locating a cryocooler in a stationary reference frame, and transferring heat from a superconductor device located in a rotating reference frame to the cryocooler through a closed circulation system external to the cryocooler. The closed circulation system interfaces the stationary reference frame with the rotating reference frame.

  13. General curvilinear coordinate systems

    NASA Technical Reports Server (NTRS)

    Thompson, J. P.

    1982-01-01

    The basic ideas of the construction and use of numerically-generated boundary-fitted coordinate systems for the numerical solution of partial differential equations are discussed. With such coordinate systems, all computation can be done on a fixed square grid in the rectangular transformed region regardless of the shape or movement of the physical boundaries. A number of different types of configurations for the transformed region and the basic transformation relations from a cartesian system to a general curvilinear system are given. The material of this paper is applicable to all types of coordinate system generation.

  14. Systems Biology of Embryogenesis

    PubMed Central

    Edelman, Lucas B.; Chandrasekaran, Sriram; Price, Nathan D.

    2010-01-01

    The development of a complete organism from a single cell involves extraordinarily complex orchestration of biological processes that vary intricately across space and time. Systems biology seeks to describe how all elements of a biological system interact in order to understand, model, and ultimately predict aspects of emergent biological processes. Embryogenesis represents an extraordinary opportunity – and challenge – for the application of systems biology. Systems approaches have already been used successfully to study various aspects of development, from complex intracellular networks to 4D models of organogenesis. Going forward, great advancements and discoveries can be expected from systems approaches applied to embryogenesis and developmental biology. PMID:20003850

  15. Photovoltaic power systems workshop

    NASA Technical Reports Server (NTRS)

    Killian, H. J.; Given, R. W.

    1978-01-01

    Discussions are presented on apparent deficiencies in NASA planning and technology development relating to a standard power module (25-35 kW) and to future photovoltaic power systems in general. Topics of discussion consider the following: (1) adequate studies on power systems; (2) whether a standard power system module should be developed from a standard spacecraft; (3) identification of proper approaches to cost reduction; (4) energy storage avoidance; (5) attitude control; (6) thermal effects of heat rejection on solar array configuration stability; (7) assembly of large power systems in space; and (8) factoring terrestrial photovoltaic work into space power systems for possible payoff.

  16. Medical Imaging System

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The MD Image System, a true-color image processing system that serves as a diagnostic aid and tool for storage and distribution of images, was developed by Medical Image Management Systems, Huntsville, AL, as a "spinoff from a spinoff." The original spinoff, Geostar 8800, developed by Crystal Image Technologies, Huntsville, incorporates advanced UNIX versions of ELAS (developed by NASA's Earth Resources Laboratory for analysis of Landsat images) for general purpose image processing. The MD Image System is an application of this technology to a medical system that aids in the diagnosis of cancer, and can accept, store and analyze images from other sources such as Magnetic Resonance Imaging.

  17. THERMAL DISTRIBUTION SYSTEM EXPERIMENT

    SciTech Connect

    KRAJEWSKI,R.F.; ANDREWS,J.W.; WEI,G.

    1999-09-01

    A laboratory experiment has been conducted which tests for the effects of distribution system purging on system Delivery Effectiveness (DE) as defined in ASHRAE 152P. The experiment is described in its configuration, instrumentation, and data acquisition system. Data gathered in the experiment is given and discussed. The results show that purging of the distribution system alone does not offer any improvement of the system DE. Additional supporting tests were conducted regarding experimental simulations of buffer zones and bare pipe and are also discussed.

  18. Nuclear propulsion systems engineering

    SciTech Connect

    Madsen, W.W.; Neuman, J.E.: Van Haaften, D.H.

    1992-12-31

    The Nuclear Energy for Rocket Vehicle Application (NERVA) program of the 1960`s and early 1970`s was dramatically successful, with no major failures during the entire testing program. This success was due in large part to the successful development of a systems engineering process. Systems engineering, properly implemented, involves all aspects of the system design and operation, and leads to optimization of theentire system: cost, schedule, performance, safety, reliability, function, requirements, etc. The process must be incorporated from the very first and continued to project completion. This paper will discuss major aspects of the NERVA systems engineering effort, and consider the implications for current nuclear propulsion efforts.

  19. Nuclear propulsion systems engineering

    SciTech Connect

    Madsen, W.W.; Neuman, J.E.: Van Haaften, D.H.

    1992-01-01

    The Nuclear Energy for Rocket Vehicle Application (NERVA) program of the 1960's and early 1970's was dramatically successful, with no major failures during the entire testing program. This success was due in large part to the successful development of a systems engineering process. Systems engineering, properly implemented, involves all aspects of the system design and operation, and leads to optimization of theentire system: cost, schedule, performance, safety, reliability, function, requirements, etc. The process must be incorporated from the very first and continued to project completion. This paper will discuss major aspects of the NERVA systems engineering effort, and consider the implications for current nuclear propulsion efforts.

  20. FRIB cryogenic distribution system

    SciTech Connect

    Ganni, Venkatarao; Dixon, Kelly D.; Laverdure, Nathaniel A.; Knudsen, Peter N.; Arenius, Dana M.; Barrios, Matthew N.; Jones, S.; Johnson, M.; Casagrande, Fabio

    2014-01-01

    The Michigan State University Facility for Rare Isotope Beams (MSU-FRIB) helium distribution system has been revised to include bayonet/warm valve type disconnects between each cryomodule and the transfer line distribution system, similar to the Thomas Jefferson National Accelerator Facility (JLab) and the Spallation Neutron Source (SNS) cryogenic distribution systems. The heat loads at various temperature levels and some of the features in the design of the distribution system are outlined. The present status, the plans for fabrication, and the procurement approach for the helium distribution system are also included.

  1. SNS Cryogenic Systems Commissioning

    NASA Astrophysics Data System (ADS)

    Hatfield, D.; Casagrande, F.; Campisi, I.; Gurd, P.; Howell, M.; Stout, D.; Strong, H.; Arenius, D.; Creel, J.; Dixon, K.; Ganni, V.; Knudsen, P.

    2006-04-01

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  2. Smart vehicular transportation systems

    SciTech Connect

    Little, C.Q.; Wilson, C.W.

    1997-05-01

    This work builds upon established Sandia intelligent systems technology to develop a unique approach for the integration of intelligent system control into the US Highway and urban transportation systems. The Sandia developed concept of the COPILOT controller integrates a human driver with computer control to increase human performance while reducing reliance on detailed driver attention. This research extends Sandia expertise in sensor based, real-time control of robotics systems to high speed transportation systems. Knowledge in the form of maps and performance characteristics of vehicles provides the automatic decision making intelligence needed to plan optimum routes, maintain safe driving speeds and distances, avoid collisions, and conserve fuel.

  3. Range Safety Systems

    NASA Technical Reports Server (NTRS)

    Schrock, Kenneth W.; Humphries, Ricky H. (Technical Monitor)

    2002-01-01

    The high kinetic and potential energy of a launch vehicle mandates there be a mechanism to minimize possible damage to provide adequate safety for the launch facilities, range, and, most importantly, the general public. The Range Safety System, sometimes called the Flight Termination System or Flight Safety System, provides the required level of safety. The Range Safety System section of the Avionics chapter will attempt to describe how adequate safety is provided, the system's design, operation, and it's interface with the rest of the launch vehicle.

  4. Space engine safety system

    NASA Technical Reports Server (NTRS)

    Maul, William A.; Meyer, Claudia M.

    1991-01-01

    A rocket engine safety system is designed to initiate control procedures which will minimize damage to the engine and vehicle or test stand in the event of an engine failure. This report describes the features and the implementation issues associated with rocket engine safety systems. Specific concerns of safety systems applied to a space-based engine and long duration space missions are discussed. Examples of safety system features and architectures are given from recent safety monitoring investigations conducted for the Space Shuttle Main Engine and for future liquid rocket engines. Also, a general design and implementation process for rocket engine safety systems is presented.

  5. Superconductor rotor cooling system

    DOEpatents

    Gamble, Bruce B.; Sidi-Yekhlef, Ahmed; Schwall, Robert E.; Driscoll, David I.; Shoykhet, Boris A.

    2002-01-01

    A system for cooling a superconductor device includes a cryocooler located in a stationary reference frame and a closed circulation system external to the cryocooler. The closed circulation system interfaces the stationary reference frame with a rotating reference frame in which the superconductor device is located. A method of cooling a superconductor device includes locating a cryocooler in a stationary reference frame, and transferring heat from a superconductor device located in a rotating reference frame to the cryocooler through a closed circulation system external to the cryocooler. The closed circulation system interfaces the stationary reference frame with the rotating reference frame.

  6. CNEOST Control Software System

    NASA Astrophysics Data System (ADS)

    Wang, X.; Zhao, H. B.; Xia, Y.; Lu, H.; Li, B.

    2015-03-01

    In 2013, CNEOST (China Near Earth Object Survey Telescope) adapted its hardware system for the new CCD camera. Based on the new system architecture, the control software is re-designed and implemented. The software system adopts the message passing mechanism via WebSocket protocol, and improves its flexibility, expansibility, and scalability. The user interface with responsive web design realizes the remote operating under both desktop and mobile devices. The stable operating of software system has greatly enhanced the operation efficiency while reducing the complexity, and has also made a successful attempt for the future system design of telescope and telescope cloud.

  7. Spacecraft Docking System

    NASA Technical Reports Server (NTRS)

    Ghofranian, Siamak (Inventor); Chuang, Li-Ping Christopher (Inventor); Motaghedi, Pejmun (Inventor)

    2016-01-01

    A method and apparatus for docking a spacecraft. The apparatus comprises elongate members, movement systems, and force management systems. The elongate members are associated with a docking structure for a spacecraft. The movement systems are configured to move the elongate members axially such that the docking structure for the spacecraft moves. Each of the elongate members is configured to move independently. The force management systems connect the movement systems to the elongate members and are configured to limit a force applied by the each of the elongate members to a desired threshold during movement of the elongate members.

  8. Cross-functional systems

    NASA Technical Reports Server (NTRS)

    Lee, Mark

    1991-01-01

    Many companies, including Xerox and Texas Instruments, are using cross functional systems to deal with the increasingly complex and competitive business environment. However, few firms within the aerospace industry appear to be aware of the significant benefits that cross functional systems can provide. Those benefits are examined and a flexible methodology is discussed that companies can use to identify and develop cross functional systems that will help improve organizational performance. In addition, some of the managerial issues are addressed that cross functional systems may raise and specific examples are used to explore networking's contributions to cross functional systems.

  9. Positive lubrication system

    NASA Technical Reports Server (NTRS)

    Smith, Dennis W.; Hooper, Fred L.

    1990-01-01

    As part of the development of an autonomous lubrication system for spin bearings, a system was developed to deliver oil to grease-lubricated bearings upon demand. This positive oil delivery system (PLUS) consists of a pressurized reservoir with a built-in solenoid valve that delivers a predictable quantity of oil to the spin bearing through a system of stainless steel tubes. Considerable testing was performed on the PLUS to characterize its performance and verify its effectiveness, along with qualifying it for flight. Additional development is underway that will lead to the fully autonomous active lubrication system.

  10. Power system restoration planning

    SciTech Connect

    Adibi, M.M. ); Fink, L.H.

    1994-02-01

    System restoration, as an extraordinary mode of system operation, requires careful planning and operator training. The generic tasks of restoration include determination of system and equipment status, preparation of plants and network for systematic restoration, reenergization of the network, and system rebuilding. The procedures for developing an effective restoration plan include formation of a qualified planning team, review of relevant system characteristics, formulation of assumptions regarding blackout scenarios, agreement on restoration goals, development of strategy and tactics, validation of the plan, training, and documentation.

  11. 2014 Runtime Systems Summit. Runtime Systems Report

    SciTech Connect

    Sarkar, Vivek; Budimlic, Zoran; Kulkani, Milind

    2016-09-19

    This report summarizes runtime system challenges for exascale computing, that follow from the fundamental challenges for exascale systems that have been well studied in past reports, e.g., [6, 33, 34, 32, 24]. Some of the key exascale challenges that pertain to runtime systems include parallelism, energy efficiency, memory hierarchies, data movement, heterogeneous processors and memories, resilience, performance variability, dynamic resource allocation, performance portability, and interoperability with legacy code. In addition to summarizing these challenges, the report also outlines different approaches to addressing these significant challenges that have been pursued by research projects in the DOE-sponsored X-Stack and OS/R programs. Since there is often confusion as to what exactly the term “runtime system” refers to in the software stack, we include a section on taxonomy to clarify the terminology used by participants in these research projects. In addition, we include a section on deployment opportunities for vendors and government labs to build on the research results from these projects. Finally, this report is also intended to provide a framework for discussing future research and development investments for exascale runtime systems, and for clarifying the role of runtime systems in exascale software.

  12. Active optical zoom system

    DOEpatents

    Wick, David V.

    2005-12-20

    An active optical zoom system changes the magnification (or effective focal length) of an optical imaging system by utilizing two or more active optics in a conventional optical system. The system can create relatively large changes in system magnification with very small changes in the focal lengths of individual active elements by leveraging the optical power of the conventional optical elements (e.g., passive lenses and mirrors) surrounding the active optics. The active optics serve primarily as variable focal-length lenses or mirrors, although adding other aberrations enables increased utility. The active optics can either be LC SLMs, used in a transmissive optical zoom system, or DMs, used in a reflective optical zoom system. By appropriately designing the optical system, the variable focal-length lenses or mirrors can provide the flexibility necessary to change the overall system focal length (i.e., effective focal length), and therefore magnification, that is normally accomplished with mechanical motion in conventional zoom lenses. The active optics can provide additional flexibility by allowing magnification to occur anywhere within the FOV of the system, not just on-axis as in a conventional system.

  13. TPC magnet cryogenic system

    SciTech Connect

    Green, M.A.; Burns, W.A.; Taylor, J.D.; Van Slyke, H.W.

    1980-03-01

    The Time Projection Chamber (TPC) magnet at LBL and its compensation solenoids are adiabatically stable superconducting solenoid magnets. The cryogenic system developed for the TPC magnet is discussed. This system uses forced two-phase tubular cooling with the two cryogens in the system. The liquid helium and liquid nitrogen are delivered through the cooled load by forced tubular flow. The only reservoirs of liquid cryogen exist in the control dewar (for liquid helium) and the conditioner dewar (for liquid nitrogen). The operation o these systems during virtually all phases of system operation are described. Photographs and diagrams of various system components are shown, and cryogenic system data are presented in the following sections: (1) heat leaks into the TPC coil package and the compensation solenoids; (2) heat leaks to various components of the TPC magnet cryogenics system besides the magnets and control dewar; (3) the control dewar and its relationship to the rest of the system; (4) the conditioner system and its role in cooling down the TPC magnet; (5) gas-cooled electrical leads and charging losses; and (6) a summation of the liquid helium and liquid nitrogen requirements for the TPC superconducting magnet system.

  14. Model-Based Systems

    NASA Technical Reports Server (NTRS)

    Frisch, Harold P.

    2007-01-01

    Engineers, who design systems using text specification documents, focus their work upon the completed system to meet Performance, time and budget goals. Consistency and integrity is difficult to maintain within text documents for a single complex system and more difficult to maintain as several systems are combined into higher-level systems, are maintained over decades, and evolve technically and in performance through updates. This system design approach frequently results in major changes during the system integration and test phase, and in time and budget overruns. Engineers who build system specification documents within a model-based systems environment go a step further and aggregate all of the data. They interrelate all of the data to insure consistency and integrity. After the model is constructed, the various system specification documents are prepared, all from the same database. The consistency and integrity of the model is assured, therefore the consistency and integrity of the various specification documents is insured. This article attempts to define model-based systems relative to such an environment. The intent is to expose the complexity of the enabling problem by outlining what is needed, why it is needed and how needs are being addressed by international standards writing teams.

  15. Intelligent pumping system developed

    SciTech Connect

    Not Available

    1983-06-01

    The oil field's first intelligent rod pumping system designed specifically to reduce the cost of pumping oil wells now is a reality. As a plus benefit, the system (called Liftronic) is compact and quiet. The new system combines an efficient mechanical design with a computer control system to reduce pumping costs. The unit stands less than 8 ft high, or approx. one-fourth the height of a comparable beam unit. It also mounts directly on the wellhead. The entire system can be concealed behind a fence or enclosed within a small building to make it a more attractive neighbor in residential, commercial, or recreational areas. It is useful also for agricultural areas where overhead irrigation systems restrict the use of many oil field pumping systems.

  16. Microgravity particle reduction system

    NASA Technical Reports Server (NTRS)

    Brandon, Vanessa; Joslin, Michelle; Mateo, Lili; Tubbs, Tracey

    1988-01-01

    The Controlled Ecological Life Support System (CELSS) project, sponsored by NASA, is assembling the knowledge required to design, construct, and operate a system which will grow and process higher plants in space for the consumption by crew members of a space station on a long term space mission. The problem of processing dry granular organic materials in microgravity is discussed. For the purpose of research and testing, wheat was chosen as the granular material to be ground into flour. Possible systems which were devised to transport wheat grains into the food processor, mill the wheat into flour, and transport the flour to the food preparation system are described. The systems were analyzed and compared and two satisfactory systems were chosen. Prototypes of the two preferred systems are to be fabricated next semester. They will be tested under simulated microgravity conditions and revised for maximum effectiveness.

  17. Space Station information systems

    NASA Technical Reports Server (NTRS)

    Swingle, W. L.; Mckay, C. W.

    1983-01-01

    The space operations information system is defined and characterized in a wide perspective. Interactive subsets of the total system are defined and discussed. Particular attention is paid to the concept of end-to-end systems and their repetitive population within the total system. High level program goals are reviewed and related to more explicit system requirements and user needs. Emphasis is placed on the utility and cost effectiveness of data system services from a user standpoint. Productivity, as a quantitative goal, in both development and operational phases is also addressed. Critical aspects of the approach to successful development of the data management system are discussed along with recommendations important to advanced development activities. Current and planned activity in both technology and advanced development areas are reviewed with emphasis on their importance to program success.

  18. Quantum system identification.

    PubMed

    Burgarth, Daniel; Yuasa, Kazuya

    2012-02-24

    The aim of quantum system identification is to estimate the ingredients inside a black box, in which some quantum-mechanical unitary process takes place, by just looking at its input-output behavior. Here we establish a basic and general framework for quantum system identification, that allows us to classify how much knowledge about the quantum system is attainable, in principle, from a given experimental setup. We show that controllable closed quantum systems can be estimated up to unitary conjugation. Prior knowledge on some elements of the black box helps the system identification. We present an example in which a Bell measurement is more efficient to identify the system. When the topology of the system is known, the framework enables us to establish a general criterion for the estimability of the coupling constants in its Hamiltonian.

  19. Coupled nonlinear dynamical systems

    NASA Astrophysics Data System (ADS)

    Sun, Hongyan

    In this dissertation, we study coupled nonlinear dynamical systems that exhibit new types of complex behavior. We numerically and analytically examine a variety of dynamical models, ranging from systems of ordinary differential equations (ODE) with novel elements of feedback to systems of partial differential equations (PDE) that model chemical pattern formation. Chaos, dynamical uncertainty, synchronization, and spatiotemporal pattern formation constitute the primary topics of the dissertation. Following the introduction in Chapter 1, we study chaos and dynamical uncertainty in Chapter 2 with coupled Lorenz systems and demonstrate the existence of extreme complexity in high-dimensional ODE systems. In Chapter 3, we demonstrate that chaos synchronization can be achieved by mutual and multiplicative coupling of dynamical systems. Chapter 4 and 5 focus on pattern formation in reaction-diffusion systems, and we investigate segregation and integration behavior of populations in competitive and cooperative environments, respectively.

  20. Synchronization of chaotic systems

    SciTech Connect

    Pecora, Louis M.; Carroll, Thomas L.

    2015-09-15

    We review some of the history and early work in the area of synchronization in chaotic systems. We start with our own discovery of the phenomenon, but go on to establish the historical timeline of this topic back to the earliest known paper. The topic of synchronization of chaotic systems has always been intriguing, since chaotic systems are known to resist synchronization because of their positive Lyapunov exponents. The convergence of the two systems to identical trajectories is a surprise. We show how people originally thought about this process and how the concept of synchronization changed over the years to a more geometric view using synchronization manifolds. We also show that building synchronizing systems leads naturally to engineering more complex systems whose constituents are chaotic, but which can be tuned to output various chaotic signals. We finally end up at a topic that is still in very active exploration today and that is synchronization of dynamical systems in networks of oscillators.

  1. Thermodynamics of Nonadditive Systems.

    PubMed

    Latella, Ivan; Pérez-Madrid, Agustín; Campa, Alessandro; Casetti, Lapo; Ruffo, Stefano

    2015-06-12

    The usual formulation of thermodynamics is based on the additivity of macroscopic systems. However, there are numerous examples of macroscopic systems that are not additive, due to the long-range character of the interaction among the constituents. We present here an approach in which nonadditive systems can be described within a purely thermodynamics formalism. The basic concept is to consider a large ensemble of replicas of the system where the standard formulation of thermodynamics can be naturally applied and the properties of a single system can be consequently inferred. After presenting the approach, we show its implementation in systems where the interaction decays as 1/r(α) in the interparticle distance r, with α smaller than the embedding dimension d, and in the Thirring model for gravitational systems.

  2. Power Systems Control Architecture

    SciTech Connect

    James Davidson

    2005-01-01

    A diagram provided in the report depicts the complexity of the power systems control architecture used by the national power structure. It shows the structural hierarchy and the relationship of the each system to those other systems interconnected to it. Each of these levels provides a different focus for vulnerability testing and has its own weaknesses. In evaluating each level, of prime concern is what vulnerabilities exist that provide a path into the system, either to cause the system to malfunction or to take control of a field device. An additional vulnerability to consider is can the system be compromised in such a manner that the attacker can obtain critical information about the system and the portion of the national power structure that it controls.

  3. Space Nuclear Power Systems

    NASA Technical Reports Server (NTRS)

    Houts, Michael G.

    2012-01-01

    Fission power and propulsion systems can enable exciting space exploration missions. These include bases on the moon and Mars; and the exploration, development, and utilization of the solar system. In the near-term, fission surface power systems could provide abundant, constant, cost-effective power anywhere on the surface of the Moon or Mars, independent of available sunlight. Affordable access to Mars, the asteroid belt, or other destinations could be provided by nuclear thermal rockets. In the further term, high performance fission power supplies could enable both extremely high power levels on planetary surfaces and fission electric propulsion vehicles for rapid, efficient cargo and crew transfer. Advanced fission propulsion systems could eventually allow routine access to the entire solar system. Fission systems could also enable the utilization of resources within the solar system.

  4. Multisource energy system project

    NASA Astrophysics Data System (ADS)

    Dawson, R. W.; Cowan, R. A.

    1987-03-01

    The mission of this project is to investigate methods of providing uninterruptible power to Army communications and navigational facilities, many of which have limited access or are located in rugged terrain. Two alternatives are currently available for deploying terrestrial stand-alone power systems: (1) conventional electric systems powered by diesel fuel, propane, or natural gas, and (2) alternative power systems using renewable energy sources such as solar photovoltaics (PV) or wind turbines (WT). The increased cost of fuels for conventional systems and the high cost of energy storage for single-source renewable energy systems have created interest in the hybrid or multisource energy system. This report will provide a summary of the first and second interim reports, final test results, and a user's guide for software that will assist in applying and designing multi-source energy systems.

  5. Pellet feed system

    SciTech Connect

    Whitfield, O.J.

    1990-08-07

    This patent describes an improvement in a stoker assembly for a solid particulate fuel burning stove. The stove including a combustion chamber, at least one remote substantially airtight fuel storage bin and a conveyor system for transporting fuel from the fuel storage bin to the combustion chamber. The improvement comprises: a conduit separate from the conveyor system, the conduit communicating between the combustion chamber and the fuel storage bin for minimizing the pressure difference along the conveyor system, such that oxygen supplied to the conveyor system is insufficient to support combustion of fuel in the conveyor system, the conduit being positioned above the conveyor system, the conveyor system including an auger and a casing for the auger.

  6. Information systems vulnerability: A systems analysis perspective

    SciTech Connect

    Wyss, G.D.; Daniel, S.L.; Schriner, H.K.; Gaylor, T.R.

    1996-07-01

    Vulnerability analyses for information systems are complicated because the systems are often geographically distributed. Sandia National Laboratories has assembled an interdisciplinary team to explore the applicability of probabilistic logic modeling (PLM) techniques (including vulnerability and vital area analysis) to examine the risks associated with networked information systems. The authors have found that the reliability and failure modes of many network technologies can be effectively assessed using fault trees and other PLM methods. The results of these models are compatible with an expanded set of vital area analysis techniques that can model both physical locations and virtual (logical) locations to identify both categories of vital areas simultaneously. These results can also be used with optimization techniques to direct the analyst toward the most cost-effective security solution.

  7. The Planetary Data System Distributed Inventory System

    NASA Technical Reports Server (NTRS)

    Hughes, J. Steven; McMahon, Susan K.

    1996-01-01

    The advent of the World Wide Web (Web) and the ability to easily put data repositories on-line has resulted in a proliferation of digital libraries. The heterogeneity of the underlying systems, the autonomy of the individual sites, and distributed nature of the technology has made both interoperability across the sites and the search for resources within a site major research topics. This article will describe a system that addresses both issues using standard Web protocols and meta-data labels to implement an inventory of on-line resources across a group of sites. The success of this system is strongly dependent on the existence of and adherence to a standards architecture that guides the management of meta-data within participating sites.

  8. Continuous recovery system for electrorefiner system

    DOEpatents

    Williamson, Mark A.; Wiedmeyer, Stanley G.; Willit, James L.; Barnes, Laurel A.; Blaskovitz, Robert J.

    2014-06-10

    A continuous recovery system for an electrorefiner system may include a trough having a ridge portion and a furrow portion. The furrow portion may include a first section and a second section. An inlet and exit pipe may be connected to the trough. The inlet pipe may include an outlet opening that opens up to the first section of the furrow portion of the trough. The exit pipe may include an entrance opening that opens up to the second section of the furrow portion of the trough. A chain may extend through the inlet and exit pipes and along the furrow portion of the trough. The chain may be in a continuous loop form. A plurality of flights may be secured to the chain. Accordingly, the desired product may be continuously harvested from the electrorefiner system without having to halt the electrical power and/or remove the cathode and anode assemblies.

  9. Control system health test system and method

    DOEpatents

    Hoff, Brian D.; Johnson, Kris W.; Akasam, Sivaprasad; Baker, Thomas M.

    2006-08-15

    A method is provided for testing multiple elements of a work machine, including a control system, a component, a sub-component that is influenced by operations of the component, and a sensor that monitors a characteristic of the sub-component. In one embodiment, the method is performed by the control system and includes sending a command to the component to adjust a first parameter associated with an operation of the component. Also, the method includes detecting a sensor signal from the sensor reflecting a second parameter associated with a characteristic of the sub-component and determining whether the second parameter is acceptable based on the command. The control system may diagnose at least one of the elements of the work machine when the second parameter of the sub-component is not acceptable.

  10. Automated Information System (AIS) Alarm System

    SciTech Connect

    Hunteman, W.

    1997-05-01

    The Automated Information Alarm System is a joint effort between Los Alamos National Laboratory, Lawrence Livermore National Laboratory, and Sandia National Laboratory to demonstrate and implement, on a small-to-medium sized local area network, an automated system that detects and automatically responds to attacks that use readily available tools and methodologies. The Alarm System will sense or detect, assess, and respond to suspicious activities that may be detrimental to information on the network or to continued operation of the network. The responses will allow stopping, isolating, or ejecting the suspicious activities. The number of sensors, the sensitivity of the sensors, the assessment criteria, and the desired responses may be set by the using organization to meet their local security policies.

  11. Automated biowaste sampling system feces monitoring system

    NASA Technical Reports Server (NTRS)

    Hunt, S. R.; Glanfield, E. J.

    1979-01-01

    The Feces Monitoring System (FMS) Program designed, fabricated, assembled and tested an engineering model waste collector system (WCS) to be used in support of life science and medical experiments related to Shuttle missions. The FMS design was patterned closely after the Shuttle WCS, including: interface provisions; mounting; configuration; and operating procedures. These similarities make it possible to eventually substitute an FMS for the Shuttle WCS of Orbiter. In addition, several advanced waste collection features, including the capability of real-time inertial fecal separation and fecal mass measurement and sampling were incorporated into the FMS design.

  12. Nemesis Autonomous Test System

    NASA Technical Reports Server (NTRS)

    Barltrop, Kevin J.; Lee, Cin-Young; Horvath, Gregory A,; Clement, Bradley J.

    2012-01-01

    A generalized framework has been developed for systems validation that can be applied to both traditional and autonomous systems. The framework consists of an automated test case generation and execution system called Nemesis that rapidly and thoroughly identifies flaws or vulnerabilities within a system. By applying genetic optimization and goal-seeking algorithms on the test equipment side, a "war game" is conducted between a system and its complementary nemesis. The end result of the war games is a collection of scenarios that reveals any undesirable behaviors of the system under test. The software provides a reusable framework to evolve test scenarios using genetic algorithms using an operation model of the system under test. It can automatically generate and execute test cases that reveal flaws in behaviorally complex systems. Genetic algorithms focus the exploration of tests on the set of test cases that most effectively reveals the flaws and vulnerabilities of the system under test. It leverages advances in state- and model-based engineering, which are essential in defining the behavior of autonomous systems. It also uses goal networks to describe test scenarios.

  13. Paravirtualization for HPC Systems

    SciTech Connect

    Youseff, L; Wolski, R; Gorda, B; Krintz, C

    2006-10-12

    Virtualization has become increasingly popular for enabling full system isolation, load balancing, and hardware multiplexing. This wide-spread use is the result of novel techniques such as paravirtualization that make virtualization systems practical and efficient. Paravirtualizing systems export an interface that is slightly different from the underlying hardware but that significantly streamlines and simplifies the virtualization process. In this work, we investigate the efficacy of using paravirtualizing software for performance-critical HPC kernels and applications. Such systems are not currently employed in HPC environments due to their perceived overhead. However, virtualization systems offer tremendous potential for benefiting HPC systems by facilitating application isolation, portability, operating system customization, and program migration. We present a comprehensive performance evaluation of Xen, a low-overhead, Linux-based, virtual machine monitor (VMM), for paravirtualization of HPC cluster systems at Lawrence Livermore National Lab (LLNL). We consider four categories of micro-benchmarks from the HPC Challenge (HPCC) and LLNL ASCI Purple suites to evaluate a wide range of subsystem-specific behaviors. In addition, we employ macro-benchmarks and HPC application to evaluate overall performance in a real setting. We also employ statistically sound methods to compare the performance of a paravirtualized kernel against three popular Linux operating systems: RedHat Enterprise 4 (RHEL4) for build versions 2.6.9 and 2.6.12 and the LLNL CHAOS kernel, a specialized version of RHEL4. Our results indicate that Xen is very efficient and practical for HPC systems.

  14. Managing hybrid marketing systems.

    PubMed

    Moriarty, R T; Moran, U

    1990-01-01

    As competition increases and costs become critical, companies that once went to market only one way are adding new channels and using new methods - creating hybrid marketing systems. These hybrid marketing systems hold the promise of greater coverage and reduced costs. But they are also hard to manage; they inevitably raise questions of conflict and control: conflict because marketing units compete for customers; control because new indirect channels are less subject to management authority. Hard as they are to manage, however, hybrid marketing systems promise to become the dominant design, replacing the "purebred" channel strategy in all kinds of businesses. The trick to managing the hybrid is to analyze tasks and channels within and across a marketing system. A map - the hybrid grid - can help managers make sense of their hybrid system. What the chart reveals is that channels are not the basic building blocks of a marketing system; marketing tasks are. The hybrid grid forces managers to consider various combinations of channels and tasks that will optimize both cost and coverage. Managing conflict is also an important element of a successful hybrid system. Managers should first acknowledge the inevitability of conflict. Then they should move to bound it by creating guidelines that spell out which customers to serve through which methods. Finally, a marketing and sales productivity (MSP) system, consisting of a central marketing database, can act as the central nervous system of a hybrid marketing system, helping managers create customized channels and service for specific customer segments.

  15. Modeling Sustainable Food Systems

    NASA Astrophysics Data System (ADS)

    Allen, Thomas; Prosperi, Paolo

    2016-05-01

    The processes underlying environmental, economic, and social unsustainability derive in part from the food system. Building sustainable food systems has become a predominating endeavor aiming to redirect our food systems and policies towards better-adjusted goals and improved societal welfare. Food systems are complex social-ecological systems involving multiple interactions between human and natural components. Policy needs to encourage public perception of humanity and nature as interdependent and interacting. The systemic nature of these interdependencies and interactions calls for systems approaches and integrated assessment tools. Identifying and modeling the intrinsic properties of the food system that will ensure its essential outcomes are maintained or enhanced over time and across generations, will help organizations and governmental institutions to track progress towards sustainability, and set policies that encourage positive transformations. This paper proposes a conceptual model that articulates crucial vulnerability and resilience factors to global environmental and socio-economic changes, postulating specific food and nutrition security issues as priority outcomes of food systems. By acknowledging the systemic nature of sustainability, this approach allows consideration of causal factor dynamics. In a stepwise approach, a logical application is schematized for three Mediterranean countries, namely Spain, France, and Italy.

  16. Distributed Deliberative Recommender Systems

    NASA Astrophysics Data System (ADS)

    Recio-García, Juan A.; Díaz-Agudo, Belén; González-Sanz, Sergio; Sanchez, Lara Quijano

    Case-Based Reasoning (CBR) is one of most successful applied AI technologies of recent years. Although many CBR systems reason locally on a previous experience base to solve new problems, in this paper we focus on distributed retrieval processes working on a network of collaborating CBR systems. In such systems, each node in a network of CBR agents collaborates, arguments and counterarguments its local results with other nodes to improve the performance of the system's global response. We describe D2ISCO: a framework to design and implement deliberative and collaborative CBR systems that is integrated as a part of jcolibritwo an established framework in the CBR community. We apply D2ISCO to one particular simplified type of CBR systems: recommender systems. We perform a first case study for a collaborative music recommender system and present the results of an experiment of the accuracy of the system results using a fuzzy version of the argumentation system AMAL and a network topology based on a social network. Besides individual recommendation we also discuss how D2ISCO can be used to improve recommendations to groups and we present a second case of study based on the movie recommendation domain with heterogeneous groups according to the group personality composition and a group topology based on a social network.

  17. Man-systems distributed system for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Lewis, J. L.

    1990-01-01

    Viewgraphs on man-systems distributed system for Space Station Freedom are presented. Topics addressed include: description of man-systems (definition, requirements, scope, subsystems, and topologies); implementation (approach, tools); man-systems interfaces (system to element and system to system); prime/supporting development relationship; selected accomplishments; and technical challenges.

  18. Power system commonality study

    NASA Astrophysics Data System (ADS)

    Littman, Franklin D.

    1992-07-01

    A limited top level study was completed to determine the commonality of power system/subsystem concepts within potential lunar and Mars surface power system architectures. A list of power system concepts with high commonality was developed which can be used to synthesize power system architectures which minimize development cost. Examples of potential high commonality power system architectures are given in this report along with a mass comparison. Other criteria such as life cycle cost (which includes transportation cost), reliability, safety, risk, and operability should be used in future, more detailed studies to select optimum power system architectures. Nineteen potential power system concepts were identified and evaluated for planetary surface applications including photovoltaic arrays with energy storage, isotope, and nuclear power systems. A top level environmental factors study was completed to assess environmental impacts on the identified power system concepts for both lunar and Mars applications. Potential power system design solutions for commonality between Mars and lunar applications were identified. Isotope, photovoltaic array (PVA), regenerative fuel cell (RFC), stainless steel liquid-metal cooled reactors (less than 1033 K maximum) with dynamic converters, and in-core thermionic reactor systems were found suitable for both lunar and Mars environments. The use of SP-100 thermoelectric (TE) and SP-100 dynamic power systems in a vacuum enclosure may also be possible for Mars applications although several issues need to be investigated further (potential single point failure of enclosure, mass penalty of enclosure and active pumping system, additional installation time and complexity). There are also technical issues involved with development of thermionic reactors (life, serviceability, and adaptability to other power conversion units). Additional studies are required to determine the optimum reactor concept for Mars applications. Various screening

  19. A contemporary view of systems engineering. [definition of system and discussion of systems approach

    NASA Technical Reports Server (NTRS)

    Miles, R. F., Jr.

    1974-01-01

    The concept of a 'system' is defined, and the 'systems approach' is discussed. Four contemporary examples of the systems approach are presented: an operations research project, the planning-programming-budgeting system, an information processing system, and aerospace programs.

  20. Soldier Integrated Headwear System: System Design Process

    DTIC Science & Technology

    2006-10-01

    Nationale Canada Abstract The aim of the Soldier Integrated Headwear System –Technology Demonstration Project (SIHS-TDP) is to empirically...determine the most promising headwear integration concept that significantly enhances the survivability and effectiveness of the future Canadian

  1. Taking a systems approach to ecological systems

    USGS Publications Warehouse

    Grace, James B.

    2015-01-01

    Increasingly, there is interest in a systems-level understanding of ecological problems, which requires the evaluation of more complex, causal hypotheses. In this issue of the Journal of Vegetation Science, Soliveres et al. use structural equation modeling to test a causal network hypothesis about how tree canopies affect understorey communities. Historical analysis suggests structural equation modeling has been under-utilized in ecology.

  2. Tool calibration system for micromachining system

    DOEpatents

    Miller, Donald M.

    1979-03-06

    A tool calibration system including a tool calibration fixture and a tool height and offset calibration insert for calibrating the position of a tool bit in a micromachining tool system. The tool calibration fixture comprises a yokelike structure having a triangular head, a cavity in the triangular head, and a port which communicates a side of the triangular head with the cavity. Yoke arms integral with the triangular head extend along each side of a tool bar and a tool head of the micromachining tool system. The yoke arms are secured to the tool bar to place the cavity around a tool bit which may be mounted to the end of the tool head. Three linear variable differential transformer's (LVDT) are adjustably mounted in the triangular head along an X axis, a Y axis, and a Z axis. The calibration insert comprises a main base which can be mounted in the tool head of the micromachining tool system in place of a tool holder and a reference projection extending from a front surface of the main base. Reference surfaces of the calibration insert and a reference surface on a tool bar standard length are used to set the three LVDT's of the calibration fixture to the tool reference position. These positions are transferred permanently to a mastering station. The tool calibration fixture is then used to transfer the tool reference position of the mastering station to the tool bit.

  3. Operational Management System for Regulated Water Systems

    NASA Astrophysics Data System (ADS)

    van Loenen, A.; van Dijk, M.; van Verseveld, W.; Berger, H.

    2012-04-01

    Most of the Dutch large rivers, canals and lakes are controlled by the Dutch water authorities. The main reasons concern safety, navigation and fresh water supply. Historically the separate water bodies have been controlled locally. For optimizating management of these water systems an integrated approach was required. Presented is a platform which integrates data from all control objects for monitoring and control purposes. The Operational Management System for Regulated Water Systems (IWP) is an implementation of Delft-FEWS which supports operational control of water systems and actively gives advice. One of the main characteristics of IWP is that is real-time collects, transforms and presents different types of data, which all add to the operational water management. Next to that, hydrodynamic models and intelligent decision support tools are added to support the water managers during their daily control activities. An important advantage of IWP is that it uses the Delft-FEWS framework, therefore processes like central data collection, transformations, data processing and presentation are simply configured. At all control locations the same information is readily available. The operational water management itself gains from this information, but it can also contribute to cost efficiency (no unnecessary pumping), better use of available storage and advise during (water polution) calamities.

  4. Geoscience laser altimeter system - stellar reference system

    SciTech Connect

    Millar, Pamela S.; Sirota, J. Marcos

    1998-01-15

    GLAS is an EOS space-based laser altimeter being developed to profile the height of the Earth's ice sheets with {approx}15 cm single shot accuracy from space under NASA's Mission to Planet Earth (MTPE). The primary science goal of GLAS is to determine if the ice sheets are increasing or diminishing for climate change modeling. This is achieved by measuring the ice sheet heights over Greenland and Antarctica to 1.5 cm/yr over 100 kmx100 km areas by crossover analysis (Zwally 1994). This measurement performance requires the instrument to determine the pointing of the laser beam to {approx}5 urad (1 arcsecond), 1-sigma, with respect to the inertial reference frame. The GLAS design incorporates a stellar reference system (SRS) to relate the laser beam pointing angle to the star field with this accuracy. This is the first time a spaceborne laser altimeter is measuring pointing to such high accuracy. The design for the stellar reference system combines an attitude determination system (ADS) with a laser reference system (LRS) to meet this requirement. The SRS approach and expected performance are described in this paper.

  5. Federated Simulations for Systems of Systems Integration

    DTIC Science & Technology

    2008-12-01

    It calls for a common definition of requirements via the Mili- tary Missions and Means framework (Sheehan, Dietz, Bray, Harris, and Wong 2004). It... missions and means framework . Technical Report TR-756, Army Material Systems Analysis Activity. Tolk, A., T. Litwin, and R. Kewley. 2008, December. A

  6. Systems Concepts Effectively Taught Using Systems Practices

    ERIC Educational Resources Information Center

    Ludwig, Claudia; Baliga, Nitin S.

    2008-01-01

    This article describes two lessons within the authors' education module entitled, Ecological Networks, that successfully teaches introductory systems content to middle and high school students. To catch students' attention when teaching these new concepts, they decided to use a network that was familiar and fun for students--a cell-phone…

  7. Database Systems. Course Three. Information Systems Curriculum.

    ERIC Educational Resources Information Center

    O'Neil, Sharon Lund; Everett, Donna R.

    This course is the third of seven in the Information Systems curriculum. The purpose of the course is to familiarize students with database management concepts and standard database management software. Databases and their roles, advantages, and limitations are explained. An overview of the course sets forth the condition and performance standard…

  8. Interstitial cells of Cajal, the Maestro in health and disease

    PubMed Central

    Mostafa, Randa M; Moustafa, Yasser M; Hamdy, Hosam

    2010-01-01

    Interstitial cells of Cajal (ICC) are important players in the symphony of gut motility. They have a very significant physiological role orchestrating the normal peristaltic activity of the digestive system. They are the pacemaker cells in gastrointestinal (GI) muscles. Absence, reduction in number or altered integrity of the ICC network may have a dramatic effect on GI system motility. More understanding of ICC physiology will foster advances in physiology of gut motility which will help in a future breakthrough in the pharmacological interventions to restore normal motor function of GI tract. This mini review describes what is known about the physiologic function and role of ICCs in GI system motility and in a variety of GI system motility disorders. PMID:20614479

  9. "Composition 8", Wassily Kandinsky

    ERIC Educational Resources Information Center

    Bader, Miriam

    2007-01-01

    In his book "A Whole New Mind," Daniel Pink describes the aptitude of Symphony as the ability to synthesize, or to put pieces together. Symphony is the capacity to see relationships, detect broad patterns, and to create by combining diverse elements together. The artist Wassily Kandinsky exemplifies Symphonic thinking. A pioneer in nonobjective…

  10. An Exploratory Comparison of Novice, Intermediate, and Expert Orchestral Conductors

    ERIC Educational Resources Information Center

    Bergee, Martin J.

    2005-01-01

    This study compared novice, "intermediate" (graduate student), and expert orchestral conductors. Two novice conductors, one graduate student in orchestral conducting, and one expert conductor led a university symphony orchestra in part of the first movement of Brahms's Symphony No. 2. Wired for sound, conductors attempted to verbalize their…

  11. A UNESCO Experiment.

    ERIC Educational Resources Information Center

    Journal of Communication, 1978

    1978-01-01

    The Symphonie Experiment Study Group reports on the experimental use of the Symphonie Satellite to link UNESCO headquarters in Paris with the Conference Centre in Nairobi, Kenya, during the nineteenth session of the General Conference. Evaluations are reported for the use of the satellite for telephone, telex, and facsimile communications. (JMF)

  12. The global Earth observation system of systems

    NASA Astrophysics Data System (ADS)

    Achache, José

    2010-05-01

    Recognizing the growing need for improved Earth observations, 140 governments and leading international organizations have established the Group on Earth Observations, or GEO, to collaborate and implement a Global Earth Observation System of Systems (GEOSS) by the year 2015. Countries and organizations are contributing their respective Earth monitoring systems, from satellites in space and in situ instruments on land, in the oceans and in the atmosphere. They are interlinking these systems so that, together, they provide a more complete picture of Earth's systems dynamics. GEO is developing common technical standards to pool observations and ensure their cross calibration and validation. It is building a web-based infrastructure to ensure easy access to the wealth of data and services contributed to, or generated by, GEOSS. GEO has been promoting the free and open sharing and dissemination of Earth observation data which has already driven significant changes in data distribution policies of several key Earth observing satellites: Landsat, Cbers and the future Sentinels of GMES. GEO is also reflecting on solutions to transition research systems into operational observing systems and ensure their long-term sustainability. First, the current status of GEOSS implementation and these core activities of GEO will be presented. Then, examples of global data sets and information systems or services developed through GEOSS will be presented: - a high-resolution global digital elevation model (DEM) based on Aster data was released by Japan and the USA. In situ measurements are now being used to improve the model as well as the stacking procedure used to develop it; - the Supersites initiative ensures coordinated access to data and information on natural hazards in geologically active regions. In light of the recent tragedy in Haiti, this project created a dedicated web site regularly updated with maps of seismicity, tectonics, Coulomb stress changes, topography, real and

  13. Climate Observing Systems: Data System Challenges

    NASA Astrophysics Data System (ADS)

    Karl, T. R.

    2001-12-01

    Existing observing and data systems have provided considerable information about past climate variations and changes. The recent reports by the Intergovernmental Panel on Climate Change, the National Research Council, and the USGCRP National Assessment of Climate Variability and Change are testaments to a vast array of knowledge. These reports also expose some serious deficiencies in our ability to discern past climate variations and change which lead to substantial uncertainties in key climate state, climate feedback, and climate forcing variables. How significant are these uncertainties? For climate trends that have our highest confidence, like the change in mean global surface temperature, the 95 percent confidence intervals amount to about two-thirds of the calculated change. With such large uncertainties it is exceedingly difficult to discern accelerated changes. For other variables, especially variables related to climate feedbacks and forcings (with exceptions for long-lived and well-mixed greenhouse gases like CO2 or CH4) or climate and weather extremes, we often have little or no information to discern trends or cannot objectively assess confidence intervals. Do we know how to reduce existing uncertainties? First and foremost, a climate observation oversight and monitoring capability is needed that tracks the gathering of the data, the processing system, and the performance of the observations, especially time-dependent biases. An organized capability does not now exist, but could be developed at a new and/or existing centers. This center(s) should then have the means and influence to fix problems and be able to establish requirements for new in-situ and satellite observing including related data systems. Such a capability should complement the following: (1) Climate observations from both space-based and in-situ platforms that are taken in ways that address climate needs and adhere to the ten principles outlined by the NRC (1999 Adequacy of Climate

  14. Autonomic nervous system and immune system interactions.

    PubMed

    Kenney, M J; Ganta, C K

    2014-07-01

    The present review assesses the current state of literature defining integrative autonomic-immune physiological processing, focusing on studies that have employed electrophysiological, pharmacological, molecular biological, and central nervous system experimental approaches. Central autonomic neural networks are informed of peripheral immune status via numerous communicating pathways, including neural and non-neural. Cytokines and other immune factors affect the level of activity and responsivity of discharges in sympathetic and parasympathetic nerves innervating diverse targets. Multiple levels of the neuraxis contribute to cytokine-induced changes in efferent parasympathetic and sympathetic nerve outflows, leading to modulation of peripheral immune responses. The functionality of local sympathoimmune interactions depends on the microenvironment created by diverse signaling mechanisms involving integration between sympathetic nervous system neurotransmitters and neuromodulators; specific adrenergic receptors; and the presence or absence of immune cells, cytokines, and bacteria. Functional mechanisms contributing to the cholinergic anti-inflammatory pathway likely involve novel cholinergic-adrenergic interactions at peripheral sites, including autonomic ganglion and lymphoid targets. Immune cells express adrenergic and nicotinic receptors. Neurotransmitters released by sympathetic and parasympathetic nerve endings bind to their respective receptors located on the surface of immune cells and initiate immune-modulatory responses. Both sympathetic and parasympathetic arms of the autonomic nervous system are instrumental in orchestrating neuroimmune processes, although additional studies are required to understand dynamic and complex adrenergic-cholinergic interactions. Further understanding of regulatory mechanisms linking the sympathetic nervous, parasympathetic nervous, and immune systems is critical for understanding relationships between chronic disease

  15. SSME Post Test Diagnostic System: Systems Section

    NASA Technical Reports Server (NTRS)

    Bickmore, Timothy

    1995-01-01

    An assessment of engine and component health is routinely made after each test firing or flight firing of a Space Shuttle Main Engine (SSME). Currently, this health assessment is done by teams of engineers who manually review sensor data, performance data, and engine and component operating histories. Based on review of information from these various sources, an evaluation is made as to the health of each component of the SSME and the preparedness of the engine for another test or flight. The objective of this project - the SSME Post Test Diagnostic System (PTDS) - is to develop a computer program which automates the analysis of test data from the SSME in order to detect and diagnose anomalies. This report primarily covers work on the Systems Section of the PTDS, which automates the analyses performed by the systems/performance group at the Propulsion Branch of NASA Marshall Space Flight Center (MSFC). This group is responsible for assessing the overall health and performance of the engine, and detecting and diagnosing anomalies which involve multiple components (other groups are responsible for analyzing the behavior of specific components). The PTDS utilizes several advanced software technologies to perform its analyses. Raw test data is analyzed using signal processing routines which detect features in the data, such as spikes, shifts, peaks, and drifts. Component analyses are performed by expert systems, which use 'rules-of-thumb' obtained from interviews with the MSFC data analysts to detect and diagnose anomalies. The systems analysis is performed using case-based reasoning. Results of all analyses are stored in a relational database and displayed via an X-window-based graphical user interface which provides ranked lists of anomalies and observations by engine component, along with supporting data plots for each.

  16. Toward intelligent information system

    NASA Astrophysics Data System (ADS)

    Komatsu, Sanzo

    NASA/RECON, the predecessor of DIALOG System, was originally designed as a user friendly system for astronauts, so that they should not miss-operate the machine in spite of tension in the outer space. Since then, DIALOG has endeavoured to develop a series of user friendly systems, such as knowledge index, inbound gateway, as well as Version II. In this so-called end user searching era, DIALOG has released a series of front end systems successively; DIALOG Business Connection, DIALOG Medical Connection and OneSearch in 1986, early and late 1987 respectively. They are all called expert systems. In this paper, the features of each system are described in some detail and the remaining critical issues are also discussed.

  17. Oxidative Tritium Decontamination System

    SciTech Connect

    Charles A. Gentile; John J. Parker; Gregory L. Guttadora; Lloyd P. Ciebiera

    2002-02-11

    The Princeton Plasma Physics Laboratory, Tritium Systems Group has developed and fabricated an Oxidative Tritium Decontamination System (OTDS), which is designed to reduce tritium surface contamination on various components and items. The system is configured to introduce gaseous ozone into a reaction chamber containing tritiated items that require a reduction in tritium surface contamination. Tritium surface contamination (on components and items in the reaction chamber) is removed by chemically reacting elemental tritium to tritium oxide via oxidation, while purging the reaction chamber effluent to a gas holding tank or negative pressure HVAC system. Implementing specific concentrations of ozone along with catalytic parameters, the system is able to significantly reduce surface tritium contamination on an assortment of expendable and non-expendable items. This paper will present the results of various experimentation involving employment of this system.

  18. NEEDS - Information Adaptive System

    NASA Technical Reports Server (NTRS)

    Kelly, W. L.; Benz, H. F.; Meredith, B. D.

    1980-01-01

    The Information Adaptive System (IAS) is an element of the NASA End-to-End Data System (NEEDS) Phase II and is focused toward onboard image processing. The IAS is a data preprocessing system which is closely coupled to the sensor system. Some of the functions planned for the IAS include sensor response nonuniformity correction, geometric correction, data set selection, data formatting, packetization, and adaptive system control. The inclusion of these sensor data preprocessing functions onboard the spacecraft will significantly improve the extraction of information from the sensor data in a timely and cost effective manner, and provide the opportunity to design sensor systems which can be reconfigured in near real-time for optimum performance. The purpose of this paper is to present the preliminary design of the IAS and the plans for its development.

  19. Idaho Explosives Detection System

    SciTech Connect

    Edward L. Reber; J. Keith Jewell; Larry G. Blackwood; Andrew J. Edwards; Kenneth W. Rohde; Edward H. Seabury

    2004-10-01

    The Idaho Explosives Detection System (IEDS) was developed at the Idaho National Laboratory (INL) to respond to threats imposed by delivery trucks carrying explosives into military bases. A full-scale prototype system has been built and is currently undergoing testing. The system consists of two racks, one on each side of a subject vehicle. Each rack includes a neutron generator and an array of NaI detectors. The two neutron generators are pulsed and synchronized. A laptop computer controls the entire system. The control software is easily operable by minimally trained staff. The system was developed to detect explosives in a medium size truck within a 5-minute measurement time. System performance was successfully demonstrated with explosives at the INL in June 2004 and at Andrews Air Force Base in July 2004.

  20. Air-storage systems

    SciTech Connect

    Doherty, T.J.

    1981-10-01

    The air storage system, the critical component making CAES technically and economically feasible, is described in three of its forms. All have geological containments and reflect economics of scale requiring fairly large plant ratings and storage capacities. All three systems also are based on good precedent experience and there are a number of willing bidders in the engineering and construction field attesting to the readiness of the technology. The salient features of each storage system type are summarized. Hard rock caverns have the widest siting opportunity in a variety of geology, are well within construction capability in good quality rock with maximum control of system design through engineering, have the highest cost of the storage system options study and the potential for longest time to startup, are difficult and expensive to expand for increased storage or plant rating. The salt-solutioned cavern has limited siting opportunities, is a very economical storage system, and storage increase is possible through cavern additions.

  1. Integrated oxygen recovery system

    NASA Technical Reports Server (NTRS)

    Lee, M. Gene; Davenport, Ronald J.

    1993-01-01

    Life Systems has conceptualized an innovative Integrated Oxygen Recovery System (IORS) applicable to advanced mission air revitalization. The IORS provides the capability to electrochemically generate metabolic oxygen (O2) and recover O2 from the space habitat atmosphere via a carbon dioxide (CO2) reduction process within a single assembly. To achieve this capability, the IORS utilizes a Solid Metal Cathode (SMC) water electrolysis unit that simultaneously serves as the Sabatier CO2 reduction reactor. The IORS enables two major life support systems currently baselined in closed loop air revitalization systems to be combined into one smaller, less complex system. This concept reduces fluidic and electrical interface requirements and eliminates a hydrogen (H2) interface. Life Systems is performing an evaluation of the IORS process directed at demonstrating performance and quantifying key physical characteristics including power, weight, and volume. Technical progress achieved during the first two months of the program is summarized.

  2. Dynamic system classifier

    NASA Astrophysics Data System (ADS)

    Pumpe, Daniel; Greiner, Maksim; Müller, Ewald; Enßlin, Torsten A.

    2016-07-01

    Stochastic differential equations describe well many physical, biological, and sociological systems, despite the simplification often made in their derivation. Here the usage of simple stochastic differential equations to characterize and classify complex dynamical systems is proposed within a Bayesian framework. To this end, we develop a dynamic system classifier (DSC). The DSC first abstracts training data of a system in terms of time-dependent coefficients of the descriptive stochastic differential equation. Thereby the DSC identifies unique correlation structures within the training data. For definiteness we restrict the presentation of the DSC to oscillation processes with a time-dependent frequency ω (t ) and damping factor γ (t ) . Although real systems might be more complex, this simple oscillator captures many characteristic features. The ω and γ time lines represent the abstract system characterization and permit the construction of efficient signal classifiers. Numerical experiments show that such classifiers perform well even in the low signal-to-noise regime.

  3. Operations management system

    NASA Technical Reports Server (NTRS)

    Brandli, A. E.; Eckelkamp, R. E.; Kelly, C. M.; Mccandless, W.; Rue, D. L.

    1990-01-01

    The objective of an operations management system is to provide an orderly and efficient method to operate and maintain aerospace vehicles. Concepts are described for an operations management system and the key technologies are highlighted which will be required if this capability is brought to fruition. Without this automation and decision aiding capability, the growing complexity of avionics will result in an unmanageable workload for the operator, ultimately threatening mission success or survivability of the aircraft or space system. The key technologies include expert system application to operational tasks such as replanning, equipment diagnostics and checkout, global system management, and advanced man machine interfaces. The economical development of operations management systems, which are largely software, will require advancements in other technological areas such as software engineering and computer hardware.

  4. Kepler's Multiple Planet Systems

    NASA Technical Reports Server (NTRS)

    Lissauer, Jack J.

    2012-01-01

    Among the 1800 Kepler targets that have candidate planets, 20% have two or more candidate planets. While most of these objects have not yet been confirmed as true planets, several considerations strongly suggest that the vast majority of these multi-candidate systems are true planetary systems. Virtually all candidate systems are stable, as tested by numerical integrations (assuming a nominal mass-radius relationship). Statistical studies performed on these candidates reveal a great deal about the architecture of planetary systems, including the typical spacing of orbits and flatness of planetary systems. The distribution of observed period ratios shows that the vast majority of candidate pairs are neither in nor near low-order mean motion resonances. Nonetheless, there are small but statistically significant excesses of candidate pairs both in resonance and spaced slightly too far apart to be in resonance, particularly near the 2:1 resonance. The characteristics of the confirmed Kepler multi-planet systems will also be discussed.

  5. Vital signs monitoring system

    NASA Technical Reports Server (NTRS)

    Steffen, Dale A. (Inventor); Sturm, Ronald E. (Inventor); Rinard, George A. (Inventor)

    1981-01-01

    A system is disclosed for monitoring vital physiological signs. Each of the system components utilizes a single hybrid circuit with each component having high accuracy without the necessity of repeated calibration. The system also has low power requirements, provides a digital display, and is of sufficiently small size to be incorporated into a hand-carried case for portable use. Components of the system may also provide independent outputs making the component useful, of itself, for monitoring one or more vital signs. The overall system preferably includes an ECG amplifier and cardiotachometer signal conditioner unit, an impedance pneumograph and respiration rate signal conditioner unit, a heart/breath rate processor unit, a temperature monitoring unit, a selector switch, a clock unit, and an LCD driver unit and associated LCDs, with the system being capable of being expanded as needed or desired, such as, for example, by addition of a systolic/diastolic blood pressure unit.

  6. Centrifugal pump fuel system

    SciTech Connect

    McGlone, M.E.; Larkins, L.J.; Johnson, R.O.; Moeller, K.A.

    1993-06-22

    A centrifugal pump fuel system for an engine driven fuel pump for an aircraft gas turbine engine is described comprising: a centrifugal pump having at constant speed rising head/flow characteristic at low flows; a plumbing system receiving flow from the pump, and having at least one control valve located down stream of and defining a discrete volume of the plumbing system; a plumbing resonant frequency defined by the discrete volume, the geometry of the plumbing system, and the bulk modulus of the fuel; a pressure difference regulating valve located adjacent to the discharge of the pump, up stream of the vast majority of the discrete volume; and the frequency response of the regulating valve being significantly less than the frequency response of the plumbing system such that the response of the regulating valve is attenuated at the resonant frequency of the plumbing system.

  7. Regional Health Information Systems

    PubMed Central

    Fuller, Sherrilynne

    1997-01-01

    Abstract In general, there is agreement that robust integrated information systems are the foundation for building successful regional health care delivery systems. Integrated Advanced Information Management System (IAIMS) institutions that, over the years, have developed strategies for creating cohesive institutional information systems and services are finding that IAIMS strategies work well in the even more complex regional environment. The key elements of IAIMS planning are described and lessons learned are discussed in the context of regional health information systems developed. The challenges of aligning the various information agencies and agendas in support of a regional health information system are complex ; however, the potential rewards for health care in quality, efficacy, and cost savings are enormous. PMID:9067887

  8. Inductive System Health Monitoring

    NASA Technical Reports Server (NTRS)

    Iverson, David L.

    2004-01-01

    The Inductive Monitoring System (IMS) software was developed to provide a technique to automatically produce health monitoring knowledge bases for systems that are either difficult to model (simulate) with a computer or which require computer models that are too complex to use for real time monitoring. IMS uses nominal data sets collected either directly from the system or from simulations to build a knowledge base that can be used to detect anomalous behavior in the system. Machine learning and data mining techniques are used to characterize typical system behavior by extracting general classes of nominal data from archived data sets. IMS is able to monitor the system by comparing real time operational data with these classes. We present a description of learning and monitoring method used by IMS and summarize some recent IMS results.

  9. Integrated oxygen recovery system

    NASA Technical Reports Server (NTRS)

    Lee, M. Gene; Davenport, Ronald J.

    1993-01-01

    Life Systems has conceptualized an innovative Integrated Oxygen Recovery System (IORS) applicable to advanced mission air revitalization. The IORS provides the capability to electrochemically generate metabolic oxygen (O2) and recover O2 from the space habitat atmosphere via a carbon dioxide (CO2) reduction process within a single assembly. To achieve this capability, the IORS utilizes a Solid Metal Cathode (SMC) water electrolysis unit that simultaneously serves as the Sabatier CO2 reduction reactor. The IORS enables two major life support systems currently baselined in closed loop air revitalization systems to be combined into one smaller, less complex system. This concept reduces fluidic and electrical interface requirements and eliminates a hydrogen (H2) interface. Life Systems is performing an evaluation of the IORS process directed at demonstrating performance and quantifying key physical characteristics including power, weight, and volume. The results of the checkout, shakedown, and initial parametric tests are summarized.

  10. Spaceborne autonomous multiprocessor systems

    NASA Technical Reports Server (NTRS)

    Fernquist, Alan

    1990-01-01

    The goal of this task is to provide technology for the specification and integration of advanced processors into the Space Station Freedom data management system environment through computer performance measurement tools, simulators, and an extended testbed facility. The approach focuses on five categories: (1) user requirements--determine the suitability of existing computer technologies and systems for real-time requirements of NASA missions; (2) system performance analysis--characterize the effects of languages, architectures, and commercially available hardware on real-time benchmarks; (3) system architecture--expand NASA's capability to solve problems with integrated numeric and symbolic requirements using advanced multiprocessor architectures; (4) parallel Ada technology--extend Ada software technology to utilize parallel architectures more efficiently; and (5) testbed--extend in-house testbed to support system performance and system analysis studies.

  11. Dynamic system classifier.

    PubMed

    Pumpe, Daniel; Greiner, Maksim; Müller, Ewald; Enßlin, Torsten A

    2016-07-01

    Stochastic differential equations describe well many physical, biological, and sociological systems, despite the simplification often made in their derivation. Here the usage of simple stochastic differential equations to characterize and classify complex dynamical systems is proposed within a Bayesian framework. To this end, we develop a dynamic system classifier (DSC). The DSC first abstracts training data of a system in terms of time-dependent coefficients of the descriptive stochastic differential equation. Thereby the DSC identifies unique correlation structures within the training data. For definiteness we restrict the presentation of the DSC to oscillation processes with a time-dependent frequency ω(t) and damping factor γ(t). Although real systems might be more complex, this simple oscillator captures many characteristic features. The ω and γ time lines represent the abstract system characterization and permit the construction of efficient signal classifiers. Numerical experiments show that such classifiers perform well even in the low signal-to-noise regime.

  12. Control system testing

    NASA Astrophysics Data System (ADS)

    Whittler, W. H.; Collart, R. E.

    1984-08-01

    A three stage process of ground testing of the Space Telescope Pointing Control System is used for verification prior to on-orbit operation. First, development tests are conducted in a laboratory environment using flight/engineering model control sensor and actuators configured with an engineering model of the flight computer and data management system breadboards. These development tests validate the results of computer simulations predicting control system performance. Integration tests bring together flight system elements and software interfaced to a software simulation of vehicle dynamics to confirm closed loop performance. The final ground test phase, flight systems testing, is conducted on the fully assembled Space Telescope, verifies interfaces with the Fine Guidance Sensors and includes a thermal vacuum testing period. During the final test phase, the Point Control System is exercised with the dynamics simulator running in real time.

  13. Layered Systems Engineering Engines

    NASA Technical Reports Server (NTRS)

    Breidenthal, Julian C.; Overman, Marvin J.

    2009-01-01

    A notation is described for depicting the relationships between multiple, contemporaneous systems engineering efforts undertaken within a multi-layer system-of-systems hierarchy. We combined the concepts of remoteness of activity from the end customer, depiction of activity on a timeline, and data flow to create a new kind of diagram which we call a "Layered Vee Diagram." This notation is an advance over previous notations because it is able to be simultaneously precise about activity, level of granularity, product exchanges, and timing; these advances provide systems engineering managers a significantly improved ability to express and understand the relationships between many systems engineering efforts. Using the new notation, we obtain a key insight into the relationship between project duration and the strategy selected for chaining the systems engineering effort between layers, as well as insights into the costs, opportunities, and risks associated with alternate chaining strategies.

  14. Environmental Control and Life Support Systems and Power Systems ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Environmental Control and Life Support Systems and Power Systems - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  15. Universal Documentation System

    DTIC Science & Technology

    2012-07-01

    through their normal channels. Phasing networks and couplers associated with antenna arrays are considered part of the antenna system. Losses in...through their normal channels. Phasing networks and couplers associated with antenna arrays are considered part of the antenna system. Losses in...normal channels. Phasing networks and couplers associated with antenna arrays are considered part of the antenna system. Losses in these elements

  16. Seismic intrusion detector system

    DOEpatents

    Hawk, Hervey L.; Hawley, James G.; Portlock, John M.; Scheibner, James E.

    1976-01-01

    A system for monitoring man-associated seismic movements within a control area including a geophone for generating an electrical signal in response to seismic movement, a bandpass amplifier and threshold detector for eliminating unwanted signals, pulse counting system for counting and storing the number of seismic movements within the area, and a monitoring system operable on command having a variable frequency oscillator generating an audio frequency signal proportional to the number of said seismic movements.

  17. Photovoltaic pump systems

    NASA Astrophysics Data System (ADS)

    Klockgether, J.; Kiessling, K. P.

    1983-09-01

    Solar pump systems for the irrigation of fields and for water supply in regions with much sunshine are discussed. For surface water and sources with a hoisting depth of 12 m, a system with immersion pumps is used. For deep sources with larger hoisting depths, an underwater motor pump was developed. Both types of pump system meet the requirements of simple installation and manipulation, safe operation, maintenance free, and high efficiency reducing the number of solar cells needed.

  18. Universal Network Access System

    DTIC Science & Technology

    2003-11-01

    successfully carried out, however. A multirate and multiprotocol system , based on software configurable, hardware accelerated processing engines has...network interface. The system will support filtering and extracting packets or cells for QoS measurements using filtering criteria, which may be...integrated designs. 6.5 Summary The intent of the research has been successfully carried out. A multirate and multiprotocol system , based on software

  19. Water Purification Systems

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A water purification/recycling system developed by Photo-Catalytics, Inc. (PCI) for NASA is commercially available. The system cleanses and recycles water, using a "photo-catalysis" process in which light or radiant energy sparks a chemical reaction. Chemically stable semiconductor powders are added to organically polluted water. The powder absorbs ultraviolet light, and pollutants are oxidized and converted to carbon dioxide. Potential markets for the system include research and pharmaceutical manufacturing applications, as well as microchip manufacture and wastewater cleansing.

  20. Drone Control System

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Drones, subscale vehicles like the Firebees, and full scale retired military aircraft are used to test air defense missile systems. The DFCS (Drone Formation Control System) computer, developed by IBM (International Business Machines) Federal Systems Division, can track ten drones at once. A program called ORACLS is used to generate software to track and control Drones. It was originally developed by Langley and supplied by COSMIC (Computer Software Management and Information Center). The program saved the company both time and money.