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Sample records for ihre verlagerung im

  1. Vernetzung im Kfz

    NASA Astrophysics Data System (ADS)

    Reif, Konrad

    Elektrische und elektronische Systeme im Kfz sind vielfach nicht voneinander unabhängig, sondern beeinflussen und ergänzen sich gegenseitig. Deshalb wurden schon bei den frühen Einspritz- und Zündsystemen Signalleitungen eingesetzt, um eine einfache Kommunikation zwischen diesen beiden Systemen zu ermöglichen. Die zunehmende Anzahl elektronischer Systeme erhöhte jedoch rasch den Bedarf und die Vielfalt an auszutauschenden Informationen. Die Anzahl der hierzu erforderlichen Signalleitungen und Stecker anschlüsse stiegen gleichermaßen, so dass die bis dahin angewandte Technik an ihre Grenzen stieß.

  2. Die physikalischen Umweltwissenschaften und das Militär Zur Erforschung Grönlands im Kalten Krieg

    NASA Astrophysics Data System (ADS)

    Heymann, Matthias

    Die modernen Umweltwissenschaften stehen heute im Mittelpunkt von Forschungsförderung und öffentlicher Aufmerksamkeit. Im Zuge des seit den 1970er Jahren erwachten Interesses am globalen Wandel der Umwelt und den damit verknüpften Problemen, ist ihre Bedeutung rasch gestiegen. Viele Wurzeln der modernen Umweltwissenschaften liegen jedoch im Kalten Krieg.

  3. Bedeutung der Informationsqualität bei Kaufentscheidungen im Internet

    NASA Astrophysics Data System (ADS)

    Gräfe, Gernot; Maaß, Christian

    Bei Kauf- und Verkaufsentscheidungen ist das Internet eine bedeutende Informationsquelle für Anbieter und Nachfrager. Während Anbieter ihre Produkte und Dienstleistungen sehr gut kennen und dazu Informationen bereitstellen, sehen sich Nachfrager oft mit einem Informationsdefizit konfrontiert. Sie haben unvollständige Kenntnisse über die Anbieter, ihre Produkte, Preise und weitere Geschäftsbedingungen und informieren sich daher im Internet. Die unausgewogene Informationsverteilung zwischen beiden Parteien wird als Informationsasymmetrie bezeichnet [Kaas 1991, S. 360], [Kleinaltenkamp 1992, S. 812], [Rohrbach 1997, S. 49].

  4. Biologie statt Philosophie? Evolutionäre Kulturerklärungen und ihre Grenzen

    NASA Astrophysics Data System (ADS)

    Illies, Christian

    Vor über siebzig Jahren fand man in einer Höhle nahe Hohlenstein-Stadel, im heutigen Baden-Württemberg, eine Frau, die keiner bekannten Spezies und nicht einmal eindeutig den Hominiden zugeordnet werden konnte. Wegen ihres Aussehens wurde sie schon bald als "Löwenfrau“ bekannt (unterdessen wird sie als "Löwenmensch“ bezeichnet, da die in solchen Fragen Klarheit schaffenden Geschlechtsteile bei der Figur fehlen und in Zeiten von gender mainstreaming derartige Festlegungen gerne vermieden werden), denn sie hatte eine menschlich-aufrechte, unbehaarte Gestalt mit weiblichen Rundungen, aber zugleich eine Mähne, sowie Augen, Ohren und Schnauze eines Löwen. Eine sehr weitläufige Verwandte des Minotaurus, so schien es, und doch wesentlich älter als alle Bewohner des Olymps, denn vermutlich wurde die knapp 30 cm große Skulptur bereits in der Altsteinzeit vor etwa 32.000 Jahren aus Mammut-Elfenbein geschnitzt. Wir wissen nicht, ob sie kultischen Zwecken diente oder ein Kind mit ihr spielte, ob sie als Glücksbringer für die Jagd oder als Schamanin mit Löwenmaske verehrt und gefürchtet wurde. Aber die Löwenfrau legt nahe, dass der Mensch schon im Morgendämmern seiner Kultur über die eigene Nähe, aber auch Distanz zum Tier nachgedacht haben muss. Die Frage nach der menschlichen Selbstverortung begegnet uns in dieser Figur, und sie bestimmt viele Zeugnisse menschlichen Nachdenkens, welche uns die Altertumswissenschaften vorlegen. Mit dem Begriff "animal rationale“, wie er unter Bezug auf Aristoteles geprägt wurde, findet sie schließlich ihre klassische, für das Abendland lange Zeit maßgebliche Antwort: Der Mensch als Tier, dessen spezifisches Merkmal die Vernunftbegabtheit ist, die ihn zugleich von allen anderen Tieren abgrenzt und über sie stellt. Aber wo genau verläuft die Grenze? Und wie kann der Mensch beides zugleich sein? Die aristotelische Definition beantwortet diese Fragen nach der Doppelnatur nicht, sondern erhebt das offene R

  5. IDSR as a Platform for Implementing IHR in African Countries

    PubMed Central

    Kasolo, Francis; Yoti, Zabulon; Bakyaita, Nathan; Gaturuku, Peter; Katz, Rebecca; Fischer, Julie E.

    2013-01-01

    Of the 46 countries in the World Health Organization (WHO) African region (AFRO), 43 are implementing Integrated Disease Surveillance and Response (IDSR) guidelines to improve their abilities to detect, confirm, and respond to high-priority communicable and noncommunicable diseases. IDSR provides a framework for strengthening the surveillance, response, and laboratory core capacities required by the revised International Health Regulations [IHR (2005)]. In turn, IHR obligations can serve as a driving force to sustain national commitments to IDSR strategies. The ability to report potential public health events of international concern according to IHR (2005) relies on early warning systems founded in national surveillance capacities. Public health events reported through IDSR to the WHO Emergency Management System in Africa illustrate the growing capacities in African countries to detect, assess, and report infectious and noninfectious threats to public health. The IHR (2005) provide an opportunity to continue strengthening national IDSR systems so they can characterize outbreaks and respond to public health events in the region. PMID:24041192

  6. Die Makrofauna und ihre Verteilung im Nordost-Felswatt von Helgoland

    NASA Astrophysics Data System (ADS)

    Janke, Klaus

    1986-03-01

    The macrofauna and its distribution in the sheltered, rocky intertidal zone of Helgoland (North Sea) was studied at 9 vertically and/or morphologically different stations from March to September in 1984. Seasonal variations in the communities were described based on each species' “conspicuousness”. A total of 172 species was found. The macrofauna shows a zoned pattern, but also the different substrata, for example, affect its distribution. The number of species increases from the upper intertidal to the upper sublittoral zone from 23 to 133 species. The upper intertidal is characterized by Littorina saxatilis, Chaetogrammarus marinus and Hyale nilssonii. Typical and abundant species of the middle and lower intertidal are Flustrellidra hispida, Littorina mariae/obtusata, Littorina littorea, Mytilus edulis and Spirorbis spirorbis. The upper sublittoral zone is characterized by Gibbula cineraria and increasing species numbers of Bryozoa, Nemertini and Opisthobranchia. Only few species (e.g. Dynamena pumila, Laomedea flexuosa, Polydora ciliata, Fabricia sabella, Jaera albifrons, Carcinus maenas) occur in the entire intertidal zone. In comparison to other very sheltered shores in Great Britain, which are also dominated by Fucaceae, the macrofauna in the Helgoland intertidal zone lacks several littoral species, such as Patella spp., Monodonta lineata, Gibbula umbilicalis, Littorina neritoides, Chthamalus spp., whereas Littorina littorea and Gibbula cineraria are highly abundant.

  7. Vertical datum unification for the International Height Reference System (IHRS)

    NASA Astrophysics Data System (ADS)

    Sánchez, Laura; Sideris, Michael G.

    2017-05-01

    The International Association of Geodesy released in July 2015 a resolution for the definition and realisation of an International Height Reference System (IHRS). According to this resolution, the IHRS coordinates are potential differences referring to the equipotential surface of the Earth's gravity field realised by the conventional value W0 = 62 636 853.4 m2s-2. A main component of the IHRS realisation is the integration of the existing height systems into the global one; that is existing vertical coordinates should be referred to one and the same reference level realised by the conventional W0. This procedure is known as vertical datum unification and its main result are the vertical datum parameters, that is the potential differences between the local and the global reference levels. In this paper, we rigorously derive the observation equations for the vertical datum unification in terms of potential quantities based on the geodetic boundary value problem (GBVP) approach. Those observation equations are then empirically evaluated for the vertical datum unification of the North American and South American height systems. In the first case, simulations performed in North America provide numerical estimates about the impact of omission errors and direct and indirect effects on the vertical datum parameters. In the second case, a combination of local geopotential numbers, ITRF coordinates, satellite altimetry observations, tide gauge registrations and high-resolution gravity field models is performed to estimate the level differences between the South American height systems and the global level W0. Results show that indirect effects vanish when a satellite-only gravity field model with a degree higher than n ≥ 180 is used for the solution of the GBVP. However, the component derived from satellite-only global gravity models has to be refined with terrestrial gravity data to minimise the omission error and its effect on the vertical datum parameter estimation

  8. Vertical datum unification for the International Height Reference System (IHRS)

    NASA Astrophysics Data System (ADS)

    Sánchez, Laura; Sideris, Michael G.

    2017-01-01

    SUMMARYThe International Association of Geodesy released in July 2015 a resolution for the definition and realisation of an International Height Reference System (<span class="hlt">IHRS</span>). According to this resolution, the <span class="hlt">IHRS</span> coordinates are potential differences referring to the equipotential surface of the Earth's gravity field realised by the conventional value W0 = 62 636 853.4 m2s-2. A main component of the <span class="hlt">IHRS</span> realisation is the integration of the existing height systems into the global one; i.e. existing vertical coordinates should be referred to one and the same reference level realised by the conventional W0. This procedure is known as vertical datum unification and its main result are the vertical datum parameters, i.e., the potential differences between the local and the global reference levels. In this paper, we rigorously derive the observation equations for the vertical datum unification in terms of potential quantities based on the geodetic boundary value problem (GBVP) approach. Those observation equations are then empirically evaluated for the vertical datum unification of the North American and South American height systems. In the first case, simulations performed in North America provide numerical estimates about the impact of omission errors and direct and indirect effects on the vertical datum parameters. In the second case, a combination of local geopotential numbers, ITRF coordinates, satellite altimetry observations, tide gauge registrations and high-resolution gravity field models is performed to estimate the level differences between the South American height systems and the global level W0. Results show that indirect effects vanish when a satellite-only gravity field model with a degree higher than n ≥ 180 is used for the solution of the GBVP. However, the component derived from satellite-only global gravity models has to be refined with terrestrial gravity data to minimise the omission error and its effect on the vertical datum parameter</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017heut.book...99T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017heut.book...99T"><span>Quantensprung Digitalisierung - Energiewirtschaft <span class="hlt">im</span> 21. Jahrhundert</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Thyen, Elmar</p> <p></p> <p>Die Energiewende wird ohne eine umfassende Digitalisierung der Energiewirtschaft Stückwerk bleiben. Die historisch gewachsene, aus hunderten fossilen Großkraftwerken getriebene Energieversorgung hat sich durch den Zubau von mehr als einer Millionen dezentraler Erzeugungseinheiten innerhalb der vergangenen 15 Jahren radikal verändert. Zum Ausgleich von Last und Erzeugung, aber auch zum Aufbau neuer Geschäftsfelder ist die digitale Technik unverzichtbar. <span class="hlt">Ihre</span> Möglichkeiten scheinen nahezu unbegrenzt, <span class="hlt">ihre</span> Rolle wird in einer zukünftig nahezu vollständig elektrifizierten Gesellschaft zunehmend wichtiger werden. Neue Anbieter drängen auf den Markt und setzen die traditionelle Energiewirtschaft unter Druck. Energieversorger, die sich dem Wandel nicht stellen, drohen den Anschluss zu verpassen. Noch werden Verbundunternehmen und Stadtwerke von weitreichenden regulatorischen Vorgaben geschützt. Beispiele aus anderen Branchen zeigen aber, dass die Digitalisierung <span class="hlt">im</span> Stande ist, regulatorische Mechanismen außer Kraft zu setzen. Zugleich verhindert die enge Regulierung und ein falsch verstandener Datenschutzbegriff in Deutschland die Entwicklung neuer Geschäftsmodelle, die energie- und volkswirtschaftlich sinnvoll wären.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10760782','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10760782"><span>[Leben <span class="hlt">im</span> Eismeer - Tauchuntersuchungen zur Biologie arktischer Meerespflanzen und Meerestiere</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lippert; Karsten; Wiencke</p> <p>2000-01-01</p> <p>Die Maske wird nochmals auf Dichtigkeit überprüft, der Knoten der Sicherungsleine mit zwei halben Schlägen fixiert, dann rutscht die Taucherin von der Eiskante in das kalte Wasser. Eine halbe Stunde vergeht, bevor <span class="hlt">ihr</span> Kopf wieder aus dem Eisloch auftaucht und sie ein großes Sammelnetz nach oben reicht, gefüllt mit verschiedenen Arten von Makroalgen. Obwohl noch große Flächen des Kongsfjordes <span class="hlt">im</span> arktischen Spitzbergen zugefroren sind und das Festland von einer dicken Schneedecke bedeckt ist, hat unter Wasser in den Algenwäldern bereits der Sommer und damit die Saison der Meeresbiologen begonnen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3005581','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3005581"><span>Assessment of core capacities for the International Health Regulations (<span class="hlt">IHR</span>[2005]) – Uganda, 2009</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2010-01-01</p> <p>Background Uganda is currently implementing the International Health Regulations (<span class="hlt">IHR</span>[2005]) within the context of Integrated Disease Surveillance and Response (IDSR). The <span class="hlt">IHR</span>(2005) require countries to assess the ability of their national structures, capacities, and resources to meet the minimum requirements for surveillance and response. This report describes the results of the assessment undertaken in Uganda. Methods We conducted a descriptive cross-sectional assessment using the protocol developed by the World Health Organisation (WHO). The data collection tools were adapted locally and administered to a convenience sample of HR(2005) stakeholders, and frequency analyses were performed. Results Ugandan national laws relevant to the <span class="hlt">IHR</span>(2005) existed, but they did not adequately support the full implementation of the <span class="hlt">IHR</span>(2005). Correspondingly, there was a designated <span class="hlt">IHR</span> National Focal Point (NFP), but surveillance activities and operational communications were limited to the health sector. All the districts (13/13) had designated disease surveillance offices, most had IDSR technical guidelines (92%, or 12/13), and all (13/13) had case definitions for infectious and zoonotic diseases surveillance. Surveillance guidelines were available at 57% (35/61) of the health facilities, while case definitions were available at 66% (40/61) of the health facilities. The priority diseases list, surveillance guidelines, case definitions and reporting tools were based on the IDSR strategy and hence lacked information on the <span class="hlt">IHR</span>(2005). The rapid response teams at national and district levels lacked food safety, chemical and radio-nuclear experts. Similarly, there were no guidelines on the outbreak response to food, chemical and radio-nuclear hazards. Comprehensive preparedness plans incorporating <span class="hlt">IHR</span>(2005) were lacking at national and district levels. A national laboratory policy existed and the strategic plan was being drafted. However, there were critical gaps hampering the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..1917104S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..1917104S"><span>Towards a first realization of the International Height Reference System (<span class="hlt">IHRS</span>)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sanchez, Laura; Ihde, Johannes; Pail, Roland; Gruber, Thomas; Barzaghi, Riccardo; Marti, Urs; Agren, Jonas; Sideris, Michael; Novak, Pavel</p> <p>2017-04-01</p> <p>The IAG Resolution No. 1 released during the IUGG 2015 General Assembly outlines five conventions for the definition of the International Height Reference System (<span class="hlt">IHRS</span>). The definition is given in terms of potential parameters: the vertical coordinates are geopotential numbers referring to an equipotential surface of the Earth's gravity field realized by the conventional value W0 = 62 636 853.4 m2s-2. The spatial reference of the position P for the potential W(P) = W(X) is given by coordinates X of the International Terrestrial Reference Frame (ITRF). This Resolution also states that parameters, observations, and data shall be related to the mean tidal system/mean crust. At present, the main challenge is the realization of the <span class="hlt">IHRS</span>; i.e., the establishment of the International Height Reference Frame (IHRF). It is expected that the IHRF follows the same structure as the ITRF: a global network with regional and national densifications, whose geopotential numbers referring to the global <span class="hlt">IHRS</span> are known. According to the GGOS objectives, the target accuracy of these global geopotential numbers is 1 x 10-2 m2s-2. In practice, the precise realization of the <span class="hlt">IHRS</span> is limited by different aspects; for instance, no unified standards or methods for the determination of the potential values W(P); application of different conventions for the gravity field modelling and the estimation of the position vectors X; inhomogeneous distribution of the geodetic infrastructure; restricted accessibility to terrestrial gravity data to increase the GGM resolution; insufficient modelling of geodynamic phenomena, etc. This may restrict the expected accuracy of 1 x 10-2 m2s-2 to some orders lower (from 10 x 10-2 m2s-2 to 100 x 10-2 m2s-2). This contribution discusses the required steps to outline a sustainable realization of the <span class="hlt">IHRS</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PhuZ...37..126K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PhuZ...37..126K"><span>Regenerative Energieträger <span class="hlt">im</span> Aufwind: Entwicklung der erneuerbaren Energien</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kohl, Harald</p> <p>2006-05-01</p> <p>2005 kam 4,6 % des deutschen Primär-Energieverbrauchs aus erneuerbaren Energiequellen, bei der Stromproduktion lag <span class="hlt">ihr</span> Anteil bei 10,2 %. Wesentliche Ursache ist der Boom bei der Windkraft, die vor allem durch Offshore-Windparks auf See weiter ausbaubar ist. Die Wasserkraft lieferte in Deutschland traditionell einen großen Beitrag zur Stromerzeugung, doch <span class="hlt">ihr</span> Ausbaupotenzial ist gering. Die Photovoltaik, die solar- und die geothermische Stromerzeugung spielen derzeit noch eine kleine Rolle. Den deutschen Bedarf an Wärmeenergie deckten 2004 die erneuerbaren Energien zu 5,4 %, vor allem aus Biomasse. Die solarthermische Wärmeerzeugung hat sich gegenüber 2000 mehr als verdoppelt. <span class="hlt">Im</span> Straßenverkehr spielen biogene Kraftstoffe mit 5,4 % noch eine untergeordnete Rolle. Bis 2050 könnte in Deutschland der Anteil regenerativer Energien am Primär-Energieverbrauch die Fünfzigprozentmarke überschreiten.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24630446','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24630446"><span>A new approach of Integrated Health Responses (<span class="hlt">IHR(s</span>)) modeling for ecological risk/health assessments of an urban stream.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kim, Ja-Hyun; Yeom, Dong-Hyuk; An, Kwang-Guk</p> <p>2014-08-01</p> <p>The objective of this study was to evaluate the ecological health of an urban stream using Integrated Health Responses (<span class="hlt">IHRs</span>). Water chemistry analysis, habitat health, and ecotoxicity tests were conducted in the stream along with analyses of molecular/biochemical, physiological biomarkers, and population-level responses in indicator species. Chemical stresses, measured as nutrient levels, ionic content and organic matter concentrations were significantly greater (p<0.01) at the downstream than the reference site (RF). The habitat health was largely impacted in the downstream reaches and had a negative relation with the land-use pattern of % urban area. Comet assay, 7-ethoxyresorufin-O-deethylase (EROD), acetylcholinesterase (AChE), and vitellogenin (VTG) were evaluated for low-level biomarker responses on DNA/physiological conditions of target species. The multi-metric fish model (Mm-F) was used to test the community-level response in relation to chemical and physical habitat stresses. The impaired responses of separate biomarker and bioindicator at the downstream sites occurred at all organizations from molecular/biochemical level to community level. Using all biomarkers/bioindicators, the star-plot model of <span class="hlt">IHRs</span> was developed and then the integrative health/risk assessments were conducted in the urban stream. The reduced values of <span class="hlt">IHRs</span> occurred in the downstream sites and the impacts were attributed to effluents from wastewater treatment plants (WTPs) and industrial complex. Ecological health impairments, thus, were evident in the urban reach, and reflected the long-term community responses as well as short-term responses of molecular biomarkers. The degradation of the urban stream was mainly due to a combined effect of chemical pollution and physical habitat modifications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4450733','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4450733"><span>Strengthening core public health capacity based on the implementation of the International Health Regulations (<span class="hlt">IHR</span>) (2005): Chinese lessons</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Liu, Bin; Sun, Yan; Dong, Qian; Zhang, Zongjiu; Zhang, Liang</p> <p>2015-01-01</p> <p>As an international legal instrument, the International Health Regulations (<span class="hlt">IHR</span>) is internationally binding in 196 countries, especially in all the member states of the World Health Organization (WHO). The <span class="hlt">IHR</span> aims to prevent, protect against, control, and respond to the international spread of disease and aims to cut out unnecessary interruptions to traffic and trade. To meet <span class="hlt">IHR</span> requirements, countries need to improve capacity construction by developing, strengthening, and maintaining core response capacities for public health risk and Public Health Emergency of International Concern (PHEIC). In addition, all the related core capacity requirements should be met before June 15, 2012. If not, then the deadline can be extended until 2016 upon request by countries. China has promoted the implementation of the <span class="hlt">IHR</span> comprehensively, continuingly strengthening the core public health capacity and advancing in core public health emergency capacity building, points of entry capacity building, as well as risk prevention and control of biological events (infectious diseases, zoonotic diseases, and food safety), radiological, nuclear, and chemical events, and other catastrophic events. With significant progress in core capacity building, China has dealt with many public health emergencies successfully, ensuring that its core public health capacity has met the <span class="hlt">IHR</span> requirements, which was reported to WHO in June 2014. This article describes the steps, measures, and related experiences in the implementation of <span class="hlt">IHR</span> in China. PMID:26029897</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28654739','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28654739"><span>Poliomyelitis eradication – the review of notifications from the years 2010-2016 sent to National <span class="hlt">IHR</span> Focal Point</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Radziszewski, Franciszek; Janiec, Janusz; Henszel, Łukasz; Izdebski, Radosław; Polański, Piotr</p> <p>2017-01-01</p> <p>Polio eradication programme was launched after World Health Assembly in 1988. Despite considerable decrease in reported cases it still constitutes a significant public health threat. All WHO member state is bound to appoint National <span class="hlt">IHR</span> Focal Point, which operates based on International Health Regulations (2005), which were enacted during the World Health Assembly in 2005. In Poland National <span class="hlt">IHR</span> Focal Point (<span class="hlt">IHR</span> NFP in Poland) operates since 2007, and is located in the Department of Epidemiology, in National Institute of Public Health - National Institute of Hygiene. Its aim is to acquire, assess and to transfer information on events which may constitute an international threat for the public health. <span class="hlt">IHR</span> NFP in Poland has an access to WHO’s Event Information Site (EIS) as well as Early Warning and Response System (EWRS) with reading-only credentials. Both platforms are of limited access (1). Among recipients of <span class="hlt">IHR</span> NFP notifications and information are experts from many fields such as epidemiology, virology, bacteriology and others- related to specific type of notification, as well as specific and appointed members of state’s administration and authorities in the field of public health. In this paper a review of notifications on the subject of poliomyelitis, sent to <span class="hlt">IHR</span> NFP in Poland in the years 2010-2016 is presented, as well as references to poliomyelitis epidemiological situation were made based on the date from Global Polio Eradication Initiative.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26029897','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26029897"><span>Strengthening core public health capacity based on the implementation of the International Health Regulations (<span class="hlt">IHR</span>) (2005): Chinese lessons.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Liu, Bin; Sun, Yan; Dong, Qian; Zhang, Zongjiu; Zhang, Liang</p> <p>2015-04-17</p> <p>As an international legal instrument, the International Health Regulations (<span class="hlt">IHR</span>) is internationally binding in 196 countries, especially in all the member states of the World Health Organization (WHO). The <span class="hlt">IHR</span> aims to prevent, protect against, control, and respond to the international spread of disease and aims to cut out unnecessary interruptions to traffic and trade. To meet <span class="hlt">IHR</span> requirements, countries need to improve capacity construction by developing, strengthening, and maintaining core response capacities for public health risk and Public Health Emergency of International Concern (PHEIC). In addition, all the related core capacity requirements should be met before June 15, 2012. If not, then the deadline can be extended until 2016 upon request by countries. China has promoted the implementation of the <span class="hlt">IHR</span> comprehensively, continuingly strengthening the core public health capacity and advancing in core public health emergency capacity building, points of entry capacity building, as well as risk prevention and control of biological events (infectious diseases, zoonotic diseases, and food safety), radiological, nuclear, and chemical events, and other catastrophic events. With significant progress in core capacity building, China has dealt with many public health emergencies successfully, ensuring that its core public health capacity has met the <span class="hlt">IHR</span> requirements, which was reported to WHO in June 2014. This article describes the steps, measures, and related experiences in the implementation of <span class="hlt">IHR</span> in China. © 2015 by Kerman University of Medical Sciences.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017hama.book.1711A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017hama.book.1711A"><span>Arbeitswissenschaft <span class="hlt">im</span> technischen Umfeld</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arndt, Klaus-Dieter</p> <p></p> <p>Die Arbeit spielt <span class="hlt">im</span> Leben des Menschen eine beherrschende Rolle. Er ist hier einer Vielzahl von Einflüssen ausgesetzt, die die Gesundheit und das Wohlbefinden beeinflussen und die weit in die übrigen Lebensbereiche hineinwirken. Aus diesem Grunde beschäftigt man sich seit Menschengedenken mit den Veränderungen <span class="hlt">im</span> Arbeitsleben und in der Arbeitswelt.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4676564','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4676564"><span>Strengthening public health laboratory capacity in Thailand for International Health Regulations (<span class="hlt">IHR</span>) (2005)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Peruski, Anne Harwood; Birmingham, Maureen; Tantinimitkul, Chawalit; Chungsamanukool, Ladawan; Chungsamanukool, Preecha; Guntapong, Ratigorn; Pulsrikarn, Chaiwat; Saengklai, Ladapan; Supawat, Krongkaew; Thattiyaphong, Aree; Wongsommart, Duangdao; Wootta, Wattanapong; Nikiema, Abdoulaye; Pierson, Antoine; Peruski, Leonard F; Liu, Xin; Rayfield, Mark A</p> <p>2015-01-01</p> <p>Introduction Thailand conducted a national laboratory assessment of core capacities related to the International Health Regulations (<span class="hlt">IHR</span>) (2005), and thereby established a baseline to measure future progress. The assessment was limited to public laboratories found within the Thai Bureau of Quality and Safety of Food, National Institute of Health and regional medical science centres. Methods The World Health Organization (WHO) laboratory assessment tool was adapted to Thailand through a participatory approach. This adapted version employed a specific scoring matrix and comprised 16 modules with a quantitative output. Two teams jointly performed the on-site assessments in December 2010 over a two-week period, in 17 public health laboratories in Thailand. The assessment focused on the capacity to identify and accurately detect pathogens mentioned in Annex 2 of the <span class="hlt">IHR</span> (2005) in a timely manner, as well as other public health priority pathogens for Thailand. Results Performance of quality management, budget and finance, data management and communications was considered strong (>90%); premises quality, specimen collection, biosafety, public health functions, supplies management and equipment availability were judged as very good (>70% but ≤90%); while microbiological capacity, staffing, training and supervision, and information technology needed improvement (>60% but ≤70%). Conclusions This assessment is a major step in Thailand towards development of an optimized and standardized national laboratory network for the detection and reporting of infectious disease that would be compliant with <span class="hlt">IHR</span> (2005). The participatory strategy employed to adapt an international tool to the Thai context can also serve as a model for use by other countries in the Region. The participatory approach probably ensured better quality and ownership of the results, while providing critical information to help decision-makers determine where best to invest finite resources. PMID:26693144</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1232492','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1232492"><span><span class="hlt">IMS</span> - MS Data Extractor</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p></p> <p>2015-10-20</p> <p>An automated drift time extraction and computed associated collision cross section software tool for small molecule analysis with ion mobility spectrometry-mass spectrometry (<span class="hlt">IMS</span>-MS). The software automatically extracts drift times and computes associated collision cross sections for small molecules analyzed using ion mobility spectrometry-mass spectrometry (<span class="hlt">IMS</span>-MS) based on a target list of expected ions provided by the user.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li class="active"><span>1</span></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_1 --> <div id="page_2" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li class="active"><span>2</span></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="21"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/752625','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/752625"><span><span class="hlt">IMS</span> applications analysis</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>RODACY,PHILIP J.; REBER,STEPHEN D.; SIMONSON,ROBERT J.; HANCE,BRADLEY G.</p> <p>2000-03-01</p> <p>This report examines the market potential of a miniature, hand-held Ion Mobility Spectrometer. Military and civilian markets are discussed, as well as applications in a variety of diverse fields. The strengths and weaknesses of competing technologies are discussed. An extensive Ion Mobility Spectrometry (<span class="hlt">IMS</span>) bibliography is included. The conclusions drawn from this study are: (1) There are a number of competing technologies that are capable of detecting explosives, drugs, biological, or chemical agents. The <span class="hlt">IMS</span> system currently represents the best available compromise regarding sensitivity, specificity, and portability. (2) The military market is not as large as the commercial market, but the military services are more likely to invest R and D funds in the system. (3) Military applications should be addressed before commercial applications are addressed. (4) There is potentially a large commercial market for rugged, hand-held Ion Mobility Spectrometer systems. Commercial users typically do not invest R and D funds in this type of equipment rather, they wait for off-the-shelf availability.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25971454','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25971454"><span>[Exercise scenario of a highly contagious, life-threatening disease in intercontinental aviation : a case report in the context of the International Health Regulations (<span class="hlt">IHR</span>)].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stich, Heribert; Guggemos, W; Mühlhaus, A; Wicklein, B; Dietl, J; Hoffmann, A; Leiwering, J; Frangoulidis, D; Zange, S; Königstein, B; Ippisch, S</p> <p>2015-07-01</p> <p>The International Health Regulations (<span class="hlt">IHR</span>) 2005 were conformed to German law on July 20, 2007 and described in detail by the Implementing Act (<span class="hlt">IHR</span> DG). According to these legal bases, "designated airports" must maintain special capacities for protection against health threats, and are also responsible for performing regular <span class="hlt">IHR</span> exercises. Representation of the optimization of established operational concepts of various professions to manage infectious biological threats without obstruction of international travel, and mediation of experience to <span class="hlt">IHR</span> professionals. An exercise based on the case scenario of a travel-related febrile illness was performed at Munich International Airport on November 11, 2013. Preparations took 6 months and the exercise itself lasted nearly 12 h. The follow-up lasted an additional 9 months. A qualitative and quantitative evaluation of the exercise was completed. From an Individual Medicine and Public Health perspective, modular work structures and risk communication functioned adequately. The medical examination of passengers was also well managed. Areas requiring further optimization included arrival/departure times of external actors, transport of the index patient to hospital and protective measures for individual participants. Overall, a defined biological threat scenario representing a double infection with two highly pathogenic germs was handled satisfactorily without affecting international air travel. Modular supply components are an effective and forward-looking means in protection against threats occurring at airports. Key success factors include sufficient staff mobility, immediate self-protection of actors involved, effective risk communication and a strong overall coordination and monitoring of the situation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19810020074','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19810020074"><span>Design, development, and field testing of Infrared Heterodyne Radiometer (<span class="hlt">IHR</span>) for remote profiling of tropospheric and stratospheric species</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Lange, R.; Savage, M.; Peyton, B.</p> <p>1981-01-01</p> <p>The performance of a dual-channel infrared heterodyne radiometer, designed to remotely monitor the concentration and vertical distribution of selected atmospheric species, is described. Ground based solar viewing measurement using the <span class="hlt">IHR</span> were performed at selected laser transitions for ammonia (NH3 and ozone O3). Flight tests were conducted aboard the Galileo II, NASA Ames CV-990, on the Latitude Survey Mission. Ozone was the selected atmospheric species for the airborne flight measurements because of the scientific interest in this atmospheric species, the availability of in situ monitors, the coordinated ozone measurements, and the availability of ground truth data. The IHS was operated in the solar viewing mode to determine ozone distributions in the stratosphere and in the nadir viewing mode to determine the ozone distribution in the troposphere. Airborne atmospheric propagation measurements also were carried out at selected CO2 laser transitions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://medlineplus.gov/ency/patientinstructions/000935.htm','NIH-MEDLINEPLUS'); return false;" href="https://medlineplus.gov/ency/patientinstructions/000935.htm"><span>Giving an <span class="hlt">IM</span> (intramuscular) injection</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>To give an <span class="hlt">IM</span> injection: Make sure you have the right amount of the right medicine in the syringe. Wash your hands well with soap and water. Dry them. Carefully find the spot where you will give the injection. Clean the skin at ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20150000598','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20150000598"><span>Advanced Interval Management (<span class="hlt">IM</span>) Concepts of Operations</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Barmore, Bryan E.; Ahmad, Nash'at N.; Underwood, Matthew C.</p> <p>2014-01-01</p> <p>This document provides a high-level description of several advanced <span class="hlt">IM</span> operations that NASA is considering for future research and development. It covers two versions of <span class="hlt">IM</span>-CSPO and <span class="hlt">IM</span> with Wake Mitigation. These are preliminary descriptions to support an initial benefits analysis</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..1913992R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..1913992R"><span>THOR Ion Mass Spectrometer (<span class="hlt">IMS</span>)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Retinò, Alessandro</p> <p>2017-04-01</p> <p>Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. The Ion Mass Spectrometer (<span class="hlt">IMS</span>) onboard THOR will provide the first high-time resolution measurements of mass-resolved ions in near-Earth space, focusing on hot ions in the foreshock, shock and magnetosheath turbulent regions. These measurements are required to study how kinetic-scale turbulent fluctuations heat and accelerate different ion species. <span class="hlt">IMS</span> will measure the full three-dimensional distribution functions of main ion species (H+, He++, O+) in the energy range 10 eV/q to 30 keV/q with energy resolution DE/E down to 10% and angular resolution down to 11.25˚ . The time resolution will be 150 ms for O+, 300 ms for He++ and ˜ 1s for O+, which correspond to ion scales in the the foreshock, shock and magnetosheath regions. Such high time resolution is achieved by mounting four identical <span class="hlt">IMS</span> units phased by 90˚ in the spacecraft spin plane. Each <span class="hlt">IMS</span> unit combines a top-hat electrostatic analyzer with deflectors at the entrance together with a time-of-flight section to perform mass selection. Adequate mass-per-charge resolution (M/q)/(ΔM/q) (≥ 8 for He++ and ≥ 3 for O+) is obtained through a 6 cm long Time-of-Flight (TOF) section. <span class="hlt">IMS</span> electronics includes a fast sweeping high voltage board that is required to make measurements at high cadence. Ion detection includes Micro Channel Plates (MCPs) combined with Application-Specific Integrated Circuits (ASICs) for charge amplification and discrimination and a discrete Time-to-Amplitude Converter (TAC) to determine the ion time of flight. A processor board will be used to for ion events formatting and will interface with the Particle Processing Unit (PPU), which will perform data processing for THOR particle detectors. The <span class="hlt">IMS</span> instrument is being designed and will be built and calibrated by an international consortium of scientific institutes from France, USA, Germany and Japan and Switzerland.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17087509','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17087509"><span>Physical and structural basis for the strong interactions of the -<span class="hlt">Im</span>Py- central pairing motif in the polyamide f-<span class="hlt">ImPyIm</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Buchmueller, Karen L; Bailey, Suzanna L; Matthews, David A; Taherbhai, Zarmeen T; Register, Janna K; Davis, Zachary S; Bruce, Chrystal D; O'Hare, Caroline; Hartley, John A; Lee, Moses</p> <p>2006-11-14</p> <p>The polyamide f-<span class="hlt">ImPyIm</span> has a higher affinity for its cognate DNA than either the parent analogue, distamycin A (10-fold), or the structural isomer, f-Py<span class="hlt">ImIm</span> (250-fold), has for its respective cognate DNA sequence. These findings have led to the formulation of a two-letter polyamide "language" in which the -<span class="hlt">Im</span>Py- central pairings associate more strongly with Watson-Crick DNA than -PyPy-, -Py<span class="hlt">Im</span>-, and -<span class="hlt">ImIm</span>-. Herein, we further characterize f-<span class="hlt">ImPyIm</span> and f-Py<span class="hlt">ImIm</span>, and we report thermodynamic and structural differences between -<span class="hlt">Im</span>Py- (f-<span class="hlt">ImPyIm</span>) and -Py<span class="hlt">Im</span>- (f-Py<span class="hlt">ImIm</span>) central pairings. DNase I footprinting studies confirmed that f-<span class="hlt">ImPyIm</span> is a stronger binder than distamycin A and f-Py<span class="hlt">ImIm</span> and that f-<span class="hlt">ImPyIm</span> preferentially binds CGCG over multiple competing sequences. The difference in the binding of f-<span class="hlt">ImPyIm</span> and f-Py<span class="hlt">ImIm</span> to their cognate sequences was supported by the Na(+)-dependent nature of DNA melting studies, in which significantly higher Na(+) concentrations were needed to match the ability of f-<span class="hlt">ImPyIm</span> to stabilize CGCG with that of f-Py<span class="hlt">ImIm</span> stabilizing CCGG. The selectivity of f-<span class="hlt">ImPyIm</span> beyond the four-base CGCG recognition site was tested by circular dichroism and isothermal titration microcalorimetry, which shows that f-<span class="hlt">ImPyIm</span> has marginal selectivity for (A.T)CGCG(A.T) over (G.C)CGCG(G.C). In addition, changes adjacent to this 6 bp binding site do not affect f-<span class="hlt">ImPyIm</span> affinity. Calorimetric studies revealed that binding of f-<span class="hlt">ImPyIm</span>, f-Py<span class="hlt">ImIm</span>, and distamycin A to their respective hairpin cognate sequences is exothermic; however, changes in enthalpy, entropy, and heat capacity (DeltaC(p)) contribute differently to formation of the 2:1 complexes for each triamide. Experimental and theoretical determinations of DeltaC(p) for binding of f-<span class="hlt">ImPyIm</span> to CGCG were in good agreement (-142 and -177 cal mol(-)(1) K(-)(1), respectively). (1)H NMR of f-<span class="hlt">ImPyIm</span> and f-Py<span class="hlt">ImIm</span> complexed with their respective cognate DNAs confirmed positively cooperative formation of distinct 2</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013SPIE.8893E..0QK','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013SPIE.8893E..0QK"><span>Landslide hazard assessment along a mountain highway in the Indian Himalayan Region (<span class="hlt">IHR</span>) using remote sensing and computational models</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krishna, Akhouri P.; Kumar, Santosh</p> <p>2013-10-01</p> <p>Landslide hazard assessments using computational models, such as artificial neural network (ANN) and frequency ratio (FR), were carried out covering one of the important mountain highways in the Central Himalaya of Indian Himalayan Region (<span class="hlt">IHR</span>). Landslide influencing factors were either calculated or extracted from spatial databases including recent remote sensing data of LANDSAT TM, CARTOSAT digital elevation model (DEM) and Tropical Rainfall Measuring Mission (TRMM) satellite for rainfall data. ANN was implemented using the multi-layered feed forward architecture with different input, output and hidden layers. This model based on back propagation algorithm derived weights for all possible parameters of landslides and causative factors considered. The training sites for landslide prone and non-prone areas were identified and verified through details gathered from remote sensing and other sources. Frequency Ratio (FR) models are based on observed relationships between the distribution of landslides and each landslide related factor. FR model implementation proved useful for assessing the spatial relationships between landslide locations and factors contributing to its occurrence. Above computational models generated respective susceptibility maps of landslide hazard for the study area. This further allowed the simulation of landslide hazard maps on a medium scale using GIS platform and remote sensing data. Upon validation and accuracy checks, it was observed that both models produced good results with FR having some edge over ANN based mapping. Such statistical and functional models led to better understanding of relationships between the landslides and preparatory factors as well as ensuring lesser levels of subjectivity compared to qualitative approaches.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3092415','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3092415"><span>Training initiatives within the AFHSC-Global Emerging Infections Surveillance and Response System: support for <span class="hlt">IHR</span> (2005)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2011-01-01</p> <p>Training is a key component of building capacity for public health surveillance and response, but has often been difficult to quantify. During fiscal 2009, the Armed Forces Health Surveillance Center, Division of Global Emerging Infections Surveillance and Response System (AFHSC-GEIS) supported 18 partner organizations in conducting 123 training initiatives in 40 countries for 3,130 U.S. military, civilian and host-country personnel. The training assisted with supporting compliance with International Health Regulations, <span class="hlt">IHR</span> (2005). Training activities in pandemic preparedness, outbreak investigation and response, emerging infectious disease (EID) surveillance and pathogen diagnostic techniques were expanded significantly. By engaging local health and other government officials and civilian institutions, the U.S. military’s role as a key stakeholder in global public health has been strengthened and has contributed to EID-related surveillance, research and capacity-building initiatives specified elsewhere in this issue. Public health and emerging infections surveillance training accomplished by AFHSC-GEIS and its Department of Defense (DoD) partners during fiscal 2009 will be tabulated and described. PMID:21388565</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eosweb.larc.nasa.gov/content/ims','SCIGOV-ASDC'); return false;" href="https://eosweb.larc.nasa.gov/content/ims"><span><span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://eosweb.larc.nasa.gov/">Atmospheric Science Data Center </a></p> <p></p> <p>2012-11-30</p> <p>Information Management System An online user interface which provides data and metadata to the science community on a 24-hour basis; accepts user orders for data; provides information about future data acquision and processing schedules ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20964441','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20964441"><span>Resistive glass <span class="hlt">IM</span>-TOFMS.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kaplan, Kimberly; Graf, Stephan; Tanner, Christian; Gonin, Marc; Fuhrer, Katrin; Knochenmuss, Richard; Dwivedi, Prabha; Hill, Herbert H</p> <p>2010-11-15</p> <p>The design of a new ion mobility mass spectrometer (<span class="hlt">IM</span>-MS) is presented. This new design features an ambient-pressure resistive glass ion mobility drift tube (RGIMS) coupled to a high-resolution time-of-flight mass spectrometer (TOFMS) by an enhanced interface that includes two segmented quadrupoles. The interface design demonstrates an increase in sensitivity while maintaining high resolving power typically achieved for ambient-pressure <span class="hlt">IMS</span> drift tubes. Performance of the prototype instrument was evaluated and the analytical figures of merit for standard solutions as well as complex samples such as human blood were determined. For a 3 μM solution of caffeine, the peak was collected in 36 s and gave a response of 10 counts/s. The detection limit (defined as 1 count/s) was calculated to be 300 nM concentration of caffeine from the response rate from the 36 s run. Controlled fragmentation of caffeine was achieved through adjustment of voltages applied on the interface lenses. Over 300 tentative metabolites were detected in human blood along with 80 isomers/isobars with ion counts >5. Isotope ratios from extracted mass spectra of selected mobility peaks were used to identify selected metabolite compounds. High separation power for both <span class="hlt">IMS</span> (resolving power, t(d)/Δt(w1/2), was 85) and MS (mass resolving power, m/Δm, maximum was 7000 with a mass accuracy between 2 and 10 ppm) was measured. Developed software for data acquisition, control and display allowed flexibility in instrument control, data evaluation and visualization.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18353654','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18353654"><span>Modifying the N-terminus of polyamides: Py<span class="hlt">ImPyIm</span> has improved sequence specificity over f-<span class="hlt">ImPyIm</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Brown, Toni; Mackay, Hilary; Turlington, Mark; Sutterfield, Arden; Smith, Traci; Sielaff, Alan; Westrate, Laura; Bruce, Chrystal; Kluza, Jerome; O'Hare, Caroline; Nguyen, Binh; Wilson, W David; Hartley, John A; Lee, Moses</p> <p>2008-05-01</p> <p>Seven N-terminus modified derivatives of a previously published minor-groove binding polyamide (f-<span class="hlt">ImPyIm</span>, 1) were synthesized and the biochemical and biophysical chemistry evaluated. These compounds were synthesized with the aim of attaining a higher level of sequence selectivity over f-<span class="hlt">ImPyIm</span> (1), a previously published strong minor-groove binder. Two compounds possessing a furan or a benzofuran moiety at the N-terminus showed a footprint of 0.5microM at the cognate ACGCGT site (determined by DNase I footprinting); however, the specificity of these compounds was not improved. In contrast, Py<span class="hlt">ImPyIm</span> (4) produced a footprint of 0.5microM but showed a superior specificity using the same technique. When evaluated by thermal melting experiments and circular dichroism using ACGCGT and the non-cognate AAATTT sequence, all compounds were shown to bind in the minor-groove of DNA and stabilize the cognate sequence much better than the non-cognate (except for the non-amido-compound that did not bind either sequence, as expected). Py<span class="hlt">ImPyIm</span> (4) was interesting as the DeltaT(m) for this compound was only 4 degrees C but the footprint was very selective. No binding was observed for this compound with a third DNA (non-cognate, ACCGGT). ITC studies on compound 4 showed exothermic binding with ACGCGT and no heat change was observed for titrating the compound to the other two DNA sequences. The heat capacity (DeltaC(p)) of the PIPI/ACGCGT complex calculated from the hydrophobic interactions and SASA calculations was comparable to the experimental value obtained from ITC (-146calmol(-1)K(-1)). SPR results provided confirmation of the sequence specificity of Py<span class="hlt">ImPyIm</span> (4), with a K(eq) value determined to be 7.1x10(6) M(-1) for the cognate sequence and no observable binding to AAATTT and ACCGGT. Molecular dynamic simulations affirmed that Py<span class="hlt">ImPyIm</span> (4) binds as a dimer in an overlapped conformation, and it fits snugly in the minor-groove of the ACGCGT oligonucleotide. Py<span class="hlt">ImPyIm</span> (4) is an</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27139344','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27139344"><span>Emerging infectious diseases not covered by routine vaccination in Europe in 2010-2015--the review of WHO and ECDC notifications for the National <span class="hlt">IHR</span> Focal Point in Poland.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Henszel, Łukasz; Janiec, Janusz; Izdebski, Radosław; Radziszewski, Franciszek; Polański, Piotr</p> <p>2015-01-01</p> <p>The National <span class="hlt">IHR</span> Focal Point is a center set up by each Member State of the World Health Organization (WHO) in accordance with the International Health Regulations (2005). The International Health Regulations (<span class="hlt">IHR</span>) were adopted on 23 May 2005 at the World Health Assembly and entered into force since 15 June 2007 as the legal instrument designed to help protect all countries from uncontrolled international spread of diseases and other urgent public health threats. According to Article 2 of <span class="hlt">IHR</span> the purpose and scope of these Regulations are to prevent, protect against, control and provide a public health response to the international spread of disease in ways that are commensurate with and restricted to public health risks, and which avoid unnecessary interference with international traffic and trade. Primarily, the scope of <span class="hlt">IHR</span> is to establish a system of early warning (in accordance with Article 6 and 7) with the functioning in each country National <span class="hlt">IHR</span> Focal Point which is available at any time to communicate with WHO <span class="hlt">IHR</span> Contact Points and other entities. The tasks of the National <span class="hlt">IHR</span> Fo- cal Point in Poland which was appointed by the Minister of Health and runs in the Department of Epidemiology, National Institute of Public Health--National Institute of Hygiene from 1 September 2007 are the notification of events that may constitute a public health emergency of international concern occurring in Poland or abroad and the dissemination of this information to the WHO, other National <span class="hlt">IHR</span> Focal Points or competent authorities responsible for public health. The task of the National <span class="hlt">IHR</span> Focal Point in Poland is also the dissemination of WHO and ECDC notifications, including recommendation and risk assessment documents. The aim of this work is the review of WHO and ECDC notifications received by National <span class="hlt">IHR</span> Focal Point in Poland in the period from 2010 to 2015 which were related to emerging infectious diseases not covered by routine vaccination programs or for which</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013eith.book..177S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013eith.book..177S"><span>Reisen <span class="hlt">im</span> freien Fall - Teil 2: Das Zwillingsparadoxon aus dem Blickwinkel der ART</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sonne, Bernd; Weiß, Reinhard</p> <p>2013-07-01</p> <p>Nachdem wir uns mit den Prinzipien der ART und einigen Beispielen vertraut gemacht haben, kommen wir nun zur Berechnung des Zwillingsparadoxons aus Sicht des reisenden Zwillings. Dabei spielt das Äquivalenzprinzip eine große Rolle. Deshalb wird die Bewegungssituation noch einmal erläutert, diesmal aus Sicht von Katrin. Sie befindet sich in ihrem System S'in Ruhe. In ihrem System läuft die Zeit t'ab. Nach dem Start fühlt Katrin jedoch eine Kraft, die sie als Gravitationskraft interpretieren kann. Sie merkt es daran, dass sie in den Sitz gedrückt wird. Nach einiger Zeit werden die Triebwerke abgeschaltet, und das Raumschiff fliegt mit konstanter Geschwindigkeit weiter, Phase 2. Anschließend wird der Schub der Triebwerke solange umgekehrt, bis das Raumschiff irgendwo mit der Geschwindigkeit null am Umkehrpunkt U landet, Phase 3 (Abb. 15.1). Die Erde, auf der sich Michael befindet, bewegt sich mit x'(t') aus Sicht von Katrin <span class="hlt">im</span> freien Fall von <span class="hlt">ihr</span> weg, s. das Experiment mit dem steigenden Fahrstuhl in Abschn. 13.2.1.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=113284&keyword=Audit&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=78747245&CFTOKEN=28277027','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=113284&keyword=Audit&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=78747245&CFTOKEN=28277027"><span>GEOSPATIAL IT/<span class="hlt">IM</span> QA CHECKLIST</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Quality assurance (QA) of information technology (IT) and Information Management (<span class="hlt">IM</span>) systems help to ensure that the end product is of known quality and integrity. As the complexity of IT & <span class="hlt">IM</span> processes increase, so does the need for regular QA evaluation. <br><br>The areas revi...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title23-vol1/pdf/CFR-2010-title23-vol1-sec500-111.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title23-vol1/pdf/CFR-2010-title23-vol1-sec500-111.pdf"><span>23 CFR 500.111 - <span class="hlt">IMS</span>.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-04-01</p> <p>... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRANSPORTATION INFRASTRUCTURE MANAGEMENT MANAGEMENT AND MONITORING SYSTEMS Management Systems § 500.111 <span class="hlt">IMS</span>. An effective <span class="hlt">IMS</span> for intermodal facilities and systems provides... facilities and systems and improvement in the coordination in planning, and implementation of air, water,...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=113284&keyword=systems+AND+audit&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=113284&keyword=systems+AND+audit&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>GEOSPATIAL IT/<span class="hlt">IM</span> QA CHECKLIST</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Quality assurance (QA) of information technology (IT) and Information Management (<span class="hlt">IM</span>) systems help to ensure that the end product is of known quality and integrity. As the complexity of IT & <span class="hlt">IM</span> processes increase, so does the need for regular QA evaluation. <br><br>The areas revi...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/988127','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/988127"><span>Ion Mobility Spectrometry (<span class="hlt">IMS</span>) and Mass Spectrometry</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Shvartsburg, Alexandre A.</p> <p>2010-04-20</p> <p>In a media of finite viscosity, the Coulomb force of external electric field moves ions with some terminal speed. This dynamics is controlled by “mobility” - a property of the interaction potential between ions and media molecules. This fact has been used to separate and characterize gas-phase ions in various modes of ion mobility spectrometry (<span class="hlt">IMS</span>) developed since 1970. Commercial <span class="hlt">IMS</span> devices were introduced in 1980-s for field detection of volatile traces such as explosives and chemical warfare agents. Coupling to soft-ionization sources, mass spectrometry (MS), and chromatographic methods in 1990-s had allowed <span class="hlt">IMS</span> to handle complex samples, enabling new applications in biological and environmental analyses, nanoscience, and other areas. Since 2003, the introduction of commercial systems by major instrument vendors started bringing the <span class="hlt">IMS</span>/MS capability to broad user community. The other major development of last decade has been the differential <span class="hlt">IMS</span> or “field asymmetric waveform IMS” (FAIMS) that employs asymmetric time-dependent electric field to sort ions not by mobility itself, but by the difference between its values in strong and weak electric fields. Coupling of FAIMS to conventional <span class="hlt">IMS</span> and stacking of conventional <span class="hlt">IMS</span> stages have enabled two-dimensional separations that dramatically expand the power of ion mobility methods.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21416168','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21416168"><span>Development of imaging mass spectrometry (<span class="hlt">IMS</span>) dataset extractor software, <span class="hlt">IMS</span> convolution.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hayasaka, Takahiro; Goto-Inoue, Naoko; Ushijima, Masaru; Yao, Ikuko; Yuba-Kubo, Akiko; Wakui, Masatoshi; Kajihara, Shigeki; Matsuura, Masaaki; Setou, Mitsutoshi</p> <p>2011-07-01</p> <p>Imaging mass spectrometry (<span class="hlt">IMS</span>) is a powerful tool for detecting and visualizing biomolecules in tissue sections. The technology has been applied to several fields, and many researchers have started to apply it to pathological samples. However, it is very difficult for inexperienced users to extract meaningful signals from enormous <span class="hlt">IMS</span> datasets, and the procedure is time-consuming. We have developed software, called <span class="hlt">IMS</span> Convolution with regions of interest (ROI), to automatically extract meaningful signals from <span class="hlt">IMS</span> datasets. The processing is based on the detection of common peaks within the ordered area in the <span class="hlt">IMS</span> dataset. In this study, the <span class="hlt">IMS</span> dataset from a mouse eyeball section was acquired by a mass microscope that we recently developed, and the peaks extracted by manual and automatic procedures were compared. The manual procedure extracted 16 peaks with higher intensity in mass spectra averaged in whole measurement points. On the other hand, the automatic procedure using <span class="hlt">IMS</span> Convolution easily and equally extracted peaks without any effort. Moreover, the use of ROIs with <span class="hlt">IMS</span> Convolution enabled us to extract the peak on each ROI area, and all of the 16 ion images on mouse eyeball tissue were from phosphatidylcholine species. Therefore, we believe that <span class="hlt">IMS</span> Convolution with ROIs could automatically extract the meaningful peaks from large-volume <span class="hlt">IMS</span> datasets for inexperienced users as well as for researchers who have performed the analysis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009luba.book..424P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009luba.book..424P"><span>Abdichtungen <span class="hlt">im</span> Verbund mit Fliesen und Platten</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Platts, Thomas</p> <p></p> <p>Abdichtungen <span class="hlt">im</span> Verbund mit Fliesen und Platten, <span class="hlt">im</span> Folgenden auch als Verbundabdichtungen oder mit Kurzzeichen als AIV bezeichnet, haben sich in der Baupraxis insbesondere in Innenräumen wegen des vereinfachten konstruktiven Aufbaus gegenüber Bahnenabdichtungen nach DIN 18195-5 [14.1] in der Mehrzahl der Ausführungen durchgesetzt und bewährt. Sie können <span class="hlt">im</span> Innen- und Außenbereich angeordnet werden und sind dadurch gekennzeichnet, dass die Nutzschicht in Boden- und Wandbereichen <span class="hlt">im</span> Dünnbettverfahren unmittelbar auf die Abdichtung aufgebracht wird. Aufwändige Zwischenschichten oder Einbauteile wie armierter Putz, Telleranker etc. entfallen (Bild 14.1) und es lassen sich geringere Aufbauhöhen realisieren.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li class="active"><span>2</span></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_2 --> <div id="page_3" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active"><span>3</span></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="41"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026854','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026854"><span>The pinhole interface for <span class="hlt">IMS</span>/MS</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Spangler, Glenn E.</p> <p>1995-01-01</p> <p>An important supplementary technique for ion mobility spectrometry (<span class="hlt">IMS</span>) is mass spectrometry (MS). A mass spectrometer coupled to an ion mobility spectrometer (<span class="hlt">IMS</span>/MS) can provide significant information on the composition of the ions contributing to an ion mobility peak. On the other hand, the interpretation of <span class="hlt">IMS</span>/MS results requires knowledge of processes which can occur at the pinhole interface. When the ion composition is a mixture of ion clusters, the observed cluster distribution may not be an accurate representation of the ion clusters in the <span class="hlt">IMS</span>. Depending on the buffer gas, lower clusters can form by equilibrating with reduced concentrations in the continuum regime of the expansion and larger clusters can form by collisional stabilization in the cooled jet stream. Besides water, nitrogen molecules can also add to the ion clusters. Even though nitrogen is non-polar, this addition is made possible by an ion-induced dipole interaction between the ion and molecule.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=MAC&pg=2&id=EJ899114','ERIC'); return false;" href="https://eric.ed.gov/?q=MAC&pg=2&id=EJ899114"><span><span class="hlt">I'm</span> a Map, <span class="hlt">I'm</span> a Green Tree</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Anderson, Daniel</p> <p>2010-01-01</p> <p><span class="hlt">I'm</span> talking about the ways we represent ourselves and our world. I've put some thoughts on the topic together here--a gathering that enacts new media creating and takes up conceptual layers like metaphors, models, and composing. The primary sources are videos from the Get a Mac campaign, aka <span class="hlt">I'm</span> a Mac; <span class="hlt">I'm</span> a PC ads. Posthuman concepts blending…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25692213','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25692213"><span><span class="hlt">IMS</span>-MS and <span class="hlt">IMS-IMS</span> investigation of the structure and stability of dimethylamine-sulfuric acid nanoclusters.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ouyang, Hui; He, Siqin; Larriba-Andaluz, Carlos; Hogan, Christopher J</p> <p>2015-03-12</p> <p>Recent studies of new particle formation events in the atmosphere suggest that nanoclusters (i.e, the species formed during the early stages of particle growth which are composed of 10(1)-10(3) molecules) may consist of amines and sulfuric acid. The physicochemical properties of sub-10 nm amine-sulfuric acid clusters are hence of interest. In this work, we measure the density, thermostability, and extent of water uptake of <8.5 nm effective diameter dimethylamine-sulfuric (DMAS) nanoclusters in the gas phase, produced via positive electrospray ionization. Specifically, we employ three systems to investigate DMAS properties: ion mobility spectrometry (<span class="hlt">IMS</span>, with a parallel-plate differential mobility analyzer) is coupled with mass spectrometry to measure masses and collision cross sections for <100 kDa positively charged nanoclusters, two differential mobility analyzers in series (<span class="hlt">IMS-IMS</span>) are used to examine thermostability, and finally a differential mobility analyzer coupled to an atmospheric pressure drift tube ion mobility spectrometer (also <span class="hlt">IMS-IMS</span>) is used for water uptake measurements. <span class="hlt">IMS</span>-MS measurements reveal that dry DMAS nanoclusters have densities of ∼1567 kg/m(3) near 300 K, independent of the ratio of dimethylamine to sulfuric acid originally present in the electrospray solution. <span class="hlt">IMS-IMS</span> thermostability studies reveal that partial pressures of DMAS nanoclusters are dependent upon the electrospray solution concentration ratio, R = [H2SO4]/[(CH3)2NH]. Extrapolating measurements, we estimate that dry DMAS nanoclusters have surface vapor pressures of order 10(-4) Pa near 300 K, with the surface vapor pressure increasing with increasing values of R through most of the probed concentration range. This suggests that nanocluster surface vapor pressures are substantially enhanced by capillarity effects (the Kelvin effect). Meanwhile, <span class="hlt">IMS-IMS</span> water uptake measurements show clearly that DMAS nanoclusters uptake water at relative humidities beyond 10% near 300</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25559875','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25559875"><span>Transversal modulation ion mobility spectrometry (<span class="hlt">IMS</span>) coupled with mass spectrometry (MS): exploring the <span class="hlt">IMS-IMS</span>-MS possibilities of the instrument.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vidal-de-Miguel, G; Macía, M; Barrios, C; Cuevas, J</p> <p>2015-02-03</p> <p>A prototype is introduced based on the transversal modulation ion mobility spectrometry (TMIMS) technique, which provides a continuous output of mobility-selected ions, greatly easing the synchronization between different analyzing stages. In the new architecture, two stages of filtration are used to drastically reduce the background produced by one stage alone. Two-stages TMIMS was coupled with two different atmospheric pressure interface mass spectrometers (MS). The new system enables <span class="hlt">IMS-IMS</span>-MS analysis and other modes of operation: <span class="hlt">IMS</span> prefiltration, <span class="hlt">IMS-IMS</span>, and full transmission mode. It provides a resolving power R > 60 in <span class="hlt">IMS</span> mode, and R > 40 in each stage of <span class="hlt">IMS-IMS</span> mode. 2-Propanol vapors were introduced in one of the stages to enhance the mobility variations, and their effect was studied on a set of tetraalkylammonium ions. We found that concentrations as low as 1% (in partial pressure) produce mobility variations as high as 20%, which suggest that <span class="hlt">IMS-IMS</span> separation using dried N2 (in one stage) and a dopant (in the other stage), could be a very powerful way to enhance the separation capacity of the <span class="hlt">IMS-IMS</span> prefiltration approach.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.S31A2696S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.S31A2696S"><span><span class="hlt">IMS</span> Seismic and Infrasound Stations Instrumental Challenges</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Starovoit, Y. O.; Dricker, I. G.; Marty, J.</p> <p>2016-12-01</p> <p>The <span class="hlt">IMS</span> seismic network is a set of monitoring facilities including 50 primary stations and 120 auxiliary stations. Besides the difference in the mode of data transmission to the IDC, technical specifications for seismographic equipment to be installed at both types of stations are essentially the same. The <span class="hlt">IMS</span> infrasound network comprises 60 facilities with the requirement of continuous data transmission to IDC. The objective of this presentation is to report instrumental challenges associated with both seismic and infrasound technologies. In context of specifications for <span class="hlt">IMS</span> seismic stations it was stressed that verification seismology is concerned with searching of reliable methods of signal detections at high frequencies. In the meantime MS/mb screening criteria between earthquakes and explosions relies on reliable detection of surface waves. The <span class="hlt">IMS</span> seismic requirements for instrumental noise and operational range of data logger are defined as certain dB level below minimum background within the required frequency band from 0.02 to 16Hz. The type of sensors response is requested to be flat either in velocity or acceleration. The compliance with <span class="hlt">IMS</span> specifications may thus introduce a challenging task when low-noise conditions have been recorded at the site. It means that as a station noise PSD approaches the NLNM it requires a high sensitive sensor to be connected to a quiet digitizer which may cause a quick system clip and waste of the available dynamic range. The experience has shown that hybrid frequency response of seismic sensors where combination of flat to velocity and flat to acceleration portions of the sensor frequency response may provide an optimal solution for utilization of the dynamic range and low digitizer noise floor. Vast efforts are also being undertaken and results achieved in the infrasound technology to standardize and optimize the response of the Wind-Noise Reduction System within the <span class="hlt">IMS</span> infrasound passband from 0.02-4Hz and to deploy</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=stories+AND+Mexico&pg=3&id=ED571713','ERIC'); return false;" href="https://eric.ed.gov/?q=stories+AND+Mexico&pg=3&id=ED571713"><span>(<span class="hlt">Im</span>)migrant Voices: An Ethnographic Inquiry into Contemporary (<span class="hlt">Im</span>)migrant Issues Faced by (<span class="hlt">Im</span>)migrant University Students</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cantu, Elizabeth A.</p> <p>2016-01-01</p> <p>This dissertation examines contemporary issues that 18 (<span class="hlt">im</span>)migrant university students faced during a time of highly militarized U.S.-Mexico border relations while living in Arizona during the time of this dissertation research. Utilizing critical race theory and public sphere theory as theoretical frameworks, the project addresses several related…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=immigrants&pg=4&id=ED571713','ERIC'); return false;" href="http://eric.ed.gov/?q=immigrants&pg=4&id=ED571713"><span>(<span class="hlt">Im</span>)migrant Voices: An Ethnographic Inquiry into Contemporary (<span class="hlt">Im</span>)migrant Issues Faced by (<span class="hlt">Im</span>)migrant University Students</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cantu, Elizabeth A.</p> <p>2016-01-01</p> <p>This dissertation examines contemporary issues that 18 (<span class="hlt">im</span>)migrant university students faced during a time of highly militarized U.S.-Mexico border relations while living in Arizona during the time of this dissertation research. Utilizing critical race theory and public sphere theory as theoretical frameworks, the project addresses several related…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=owl&pg=2&id=EJ836693','ERIC'); return false;" href="https://eric.ed.gov/?q=owl&pg=2&id=EJ836693"><span>A Learning Design Ontology Based on the <span class="hlt">IMS</span> Specification</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Amorim, Ricardo R.; Lama, Manuel; Sanchez, Eduardo; Riera, Adolfo; Vila, Xose A.</p> <p>2006-01-01</p> <p>In this paper, we present an ontology to represent the semantics of the <span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span> LD) specification, a meta-language used to describe the main elements of the learning design process. The motivation of this work relies on the expressiveness limitations found on the current XML-Schema implementation of the <span class="hlt">IMS</span> LD conceptual model. To…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=owl&pg=2&id=EJ836693','ERIC'); return false;" href="http://eric.ed.gov/?q=owl&pg=2&id=EJ836693"><span>A Learning Design Ontology Based on the <span class="hlt">IMS</span> Specification</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Amorim, Ricardo R.; Lama, Manuel; Sanchez, Eduardo; Riera, Adolfo; Vila, Xose A.</p> <p>2006-01-01</p> <p>In this paper, we present an ontology to represent the semantics of the <span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span> LD) specification, a meta-language used to describe the main elements of the learning design process. The motivation of this work relies on the expressiveness limitations found on the current XML-Schema implementation of the <span class="hlt">IMS</span> LD conceptual model. To…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://kidshealth.org/en/teens/flu-pregnant.html','NIH-MEDLINEPLUS'); return false;" href="http://kidshealth.org/en/teens/flu-pregnant.html"><span><span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot?</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>... Surgery? A Week of Healthy Breakfasts Shyness <span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot? KidsHealth > For Teens > <span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot? A A A I just found out that <span class="hlt">I'm</span> 6 weeks pregnant. Do I need to get ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23043344','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23043344"><span>Multi-level stressor analysis from the DNA/biochemical level to community levels in an urban stream and integrative health response (<span class="hlt">IHR</span>) assessments.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lee, Jae Hoon; Kim, Joon Ha; Oh, Hee-Mock; An, Kwang-Guk</p> <p>2013-01-01</p> <p>The objectives of this study were to identify multi-level stressors at the DNA/biochemical level to the community level in fish in an urban stream and to develop an integrative health response (<span class="hlt">IHR</span>) model for ecological health diagnosis. A pristine control site (S (c) ) and an impacted site (S (i) ) were selected from among seven pre-screened sites studied over seven years. Various chemical analyses indicated that nutrient enrichment (Nitrogen, Phosphorus) and organic pollution were significantly greater (t > 8.783, p < 0.01) at the S (i) site compared to the S (c) site. Single-cell gel electrophoresis (comet assays) of DNA-level impairment indicated significantly (t = 5.678, p < 0.01) greater tail intensity, expressed as % tail-DNA, at the S (i) site and genotoxic responses were detected in the downstream reach. Ethoxyresorufin-O-deethylase (EROD) assays, as a physiological bioindicator, were 2.8-fold higher (p < 0.05, NK-test after ANOVA) at the S (i) site. Tissue analysis using a necropsy-based health assessment index (NHAI) showed distinct internal organ disorders in three tissues, i.e., liver, kidney, and gill, at the S (i) site. Population-level analysis using the sentinel species Zacco platypus showed that the regression coefficient (b) was 3.012 for the S (i) site and 2.915 for the S (c) site, indicating population skewness in the downstream reach. Community-level health was impaired at the S (i) site based on an index of biological integrity (IBI), and physical habitat modifications were identified by a qualitative habitat evaluation index (QHEI). Overall, the model values for the integrative health response (<span class="hlt">IHR</span>), developed using the star plot approach, were 3.22 (80.5%) at the S (c) site and 0.74 (18.5%) at the S (i) site, indicating that, overall, ecological health impairments were evident in the urban reach. Our study was based on multi-level approaches using biological organization and the results suggest that there is a pivotal point of linkage</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1815367R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1815367R"><span>THOR Ion Mass Spectrometer instrument - <span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Retinò, Alessandro; Kucharek, Harald; Saito, Yoshifumi; Fraenz, Markus; Verdeil, Christophe; Leblanc, Frederic; Techer, Jean-Denis; Jeandet, Alexis; Macri, John; Gaidos, John; Granoff, Mark; Yokota, Shoichiro; Fontaine, Dominique; Berthomier, Matthieu; Delcourt, Dominique; Kistler, Lynn; Galvin, Antoniette; Kasahara, Satoshi; Kronberg, Elena</p> <p>2016-04-01</p> <p>Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. Specifically, THOR will study how turbulent fluctuations at kinetic scales heat and accelerate particles in different turbulent environments within the near-Earth space. To achieve this goal, THOR payload is being designed to measure electromagnetic fields and particle distribution functions with unprecedented resolution and accuracy. Here we present the Ion Mass Spectrometer (<span class="hlt">IMS</span>) instrument that will measure the full three-dimensional distribution functions of near-Earth main ion species (H+, He+, He++ and O+) at high time resolution (~ 150 ms for H+ , ~ 300 ms for He++) with energy resolution down to ~ 10% in the range 10 eV/q to 30 keV/q and angular resolution ~ 10°. Such high time resolution is achieved by mounting multiple sensors around the spacecraft body, in similar fashion to the MMS/FPI instrument. Each sensor combines a top-hat electrostatic analyzer with deflectors at the entrance together with a time-of-flight section to perform mass selection. <span class="hlt">IMS</span> electronics includes a fast sweeping high voltage board that is required to make measurements at high cadence. Ion detection includes Micro Channel Plates (MCP) combined with Application-Specific Integrated Circuits (ASICs) for charge amplification, discrimination and time-to-digital conversion (TDC). <span class="hlt">IMS</span> is being designed to address many of THOR science requirements, in particular ion heating and acceleration by turbulent fluctuations in foreshock, shock and magnetosheath regions. The <span class="hlt">IMS</span> instrument is being designed and will be built by an international consortium of scientific institutes with main hardware contributions from France, USA, Japan and Germany.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1010347','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1010347"><span>Toward an Intelligent Ion Mobility Spectrometer (<span class="hlt">IMS</span>)</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Timothy R. McJunkin; Jill R. Scott; Carla J. Miller</p> <p>2003-07-01</p> <p>The ultimate goal is to design and build a very smart ion mobility spectrometer (<span class="hlt">IMS</span>) that can operate autonomously. To accomplish this, software capable of interpreting spectra so that it can be used in control loops for data interpretation as well as adjusting instrument parameters is being developed. Fuzzy logic and fuzzy numbers are used in this <span class="hlt">IMS</span> spectra classification scheme. Fuzzy logic provides a straight forward method for developing a classification/detection system, whenever rules for classifying the spectra can be described linguistically. Instead of using 'max' and 'min' values, the product of the truth values is used to determine class membership. Using the product allows rule-bases that utilize the AND function to allow each condition to discount truth value in determining membership, while rule-bases with an OR function are allowed to accumulate membership. Fuzzy numbers allow encapsulation of the uncertainties due to ion mobility peak widths as well as measured instrumental parameters, such as pressure and temperature. Associating a peak with a value of uncertainty, in addition to making adjustments to the mobility calculation based on variations in measured parameters, enables unexpected shifts to be more reliably detected and accounted for; thereby, reducing the opportunity for 'false negative' results. The measure of uncertainty is anticipated to serve the additional purpose of diagnosing the operational conditions of the <span class="hlt">IMS</span> instrument.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21143830','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21143830"><span>Laboratory capacity building for the International Health Regulations (<span class="hlt">IHR</span>[2005]) in resource-poor countries: the experience of the African Field Epidemiology Network (AFENET).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Masanza, Monica Musenero; Nqobile, Ndlovu; Mukanga, David; Gitta, Sheba Nakacubo</p> <p>2010-12-03</p> <p>Laboratory is one of the core capacities that countries must develop for the implementation of the International Health Regulations (<span class="hlt">IHR</span>[2005]) since laboratory services play a major role in all the key processes of detection, assessment, response, notification, and monitoring of events. While developed countries easily adapt their well-organized routine laboratory services, resource-limited countries need considerable capacity building as many gaps still exist. In this paper, we discuss some of the efforts made by the African Field Epidemiology Network (AFENET) in supporting laboratory capacity development in the Africa region. The efforts range from promoting graduate level training programs to building advanced technical, managerial and leadership skills to in-service short course training for peripheral laboratory staff. A number of specific projects focus on external quality assurance, basic laboratory information systems, strengthening laboratory management towards accreditation, equipment calibration, harmonization of training materials, networking and provision of pre-packaged laboratory kits to support outbreak investigation. Available evidence indicates a positive effect of these efforts on laboratory capacity in the region. However, many opportunities exist, especially to support the roll-out of these projects as well as attending to some additional critical areas such as biosafety and biosecuity. We conclude that AFENET's approach of strengthening national and sub-national systems provide a model that could be adopted in resource-limited settings such as sub-Saharan Africa.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/790859','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/790859"><span>Evaluation of Arizona's enhanced <span class="hlt">I/M</span> program</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Wenzel, Tom</p> <p>1999-04-21</p> <p>MOBILE5 slightly overpredicts initial reductions in CO and HC, and dramatically overpredicts initial reductions in NOx. About one-third of the vehicles that fail initial <span class="hlt">I/M</span> testing do not complete the <span class="hlt">I/M</span> program. Only a small portion of these receive a waiver. Initial <span class="hlt">I/M</span> repair effectiveness as measured by remote sensing is only half of that as measured by <span class="hlt">IM</span>240. Possible causes are sensitivity to operating mode, and how long after repair emissions are measured. 37% of the vehicles that initially fail and eventually pass in 1995 fail again in 1997. Half of these fail for the same combination of pollutants in both years. Vehicles that never pass the <span class="hlt">Im</span>240 are still being driven in the <span class="hlt">I/M</span> area; these vehicles are from all model years.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011dui..book..143P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011dui..book..143P"><span>Definition von Datenarten zur konsistenten Kommunikation <span class="hlt">im</span> Unternehmen</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Piro, Andrea; Gebauer, Marcus</p> <p></p> <p>Probleme in der Informationsqualität (IQ) treten in den unterschiedlichsten Bereichen eines Unternehmens auf und werden durch die unterschiedlichsten Bereiche verursacht. Daher ist es um so wichtiger, diese Probleme klar und eindeutig kommunizieren zu können. Insbesondere wenn Kollegen fachübergreifend IQ-Probleme beheben wollen, kann dies schwierig sein. Erst wenn klar ist, worüber geredet wird, und häufig sind dies Datenfelder und <span class="hlt">ihr</span> Inhalt, kann das Problem eindeutig beschrieben und gelöst werden.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008dain.book..143P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008dain.book..143P"><span>Definition von Datenarten zur konsistenten Kommunikation <span class="hlt">im</span> Unternehmen</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Piro, Andrea; Gebauer, Marcus</p> <p></p> <p>Probleme in der Informationsqualität (IQ) treten in den unterschiedlichsten Bereichen eines Unternehmens auf und werden durch die unterschiedlichsten Bereiche verursacht. Daher ist es um so wichtiger, diese Probleme klar und eindeutig kommunizieren zu können. Insbesondere wenn Kollegen fachübergreifend IQProbleme beheben wollen, kann dies schwierig sein. Erst wenn klar ist, worüber geredet wird, und häufig sind dies Datenfelder und <span class="hlt">ihr</span> Inhalt, kann das Problem eindeutig beschrieben und gelöst werden.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1994dkdj.book.....K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1994dkdj.book.....K"><span>Die Kometen der Jahre 1531 bis 1539 und <span class="hlt">ihre</span> Bedeutung für die spätere Entwicklung der Kometenforschung.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kokott, W.</p> <p></p> <p>Contents: 1. Historisches Umfeld und spätere Entwicklungen. 2. Kometen als Objekte quantitativer Beobachtung <span class="hlt">im</span> geschlossenen Universum der Epoche. 3. Verlauf der Kometenerscheinungen der Jahre 1531 bis 1539. 4. Die Bedeutung der Kometen der Jahre 1531 bis 1539 für die Entwicklung der Astronomie bis Tycho Brahe und für die Kometentheorie späterer Jahrhunderte. 5. Neuere Literatur und Spezialprobleme.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED108629.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED108629.pdf"><span>OPSN: The <span class="hlt">IMS</span> COMSYS 1 and 2 Data Preprocessing System.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Yu, John</p> <p></p> <p>The Instructional Management System (<span class="hlt">IMS</span>) developed by the Southwest Regional Laboratory (SWRL) processes student and teacher-generated data through the use of an optical scanner that produces a magnetic tape (Scan Tape) for input to <span class="hlt">IMS</span>. A series of computer routines, OPSN, preprocesses the Scan Tape and prepares the data for transmission to the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://kidshealth.org/en/teens/flu-pregnant.html','NIH-MEDLINEPLUS'); return false;" href="https://kidshealth.org/en/teens/flu-pregnant.html"><span><span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot?</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>... Shyness <span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot? KidsHealth > For Teens > <span class="hlt">I'm</span> Pregnant. Should I Get a Flu Shot? Print A A A I just found ... weeks pregnant. Do I need to get the flu vaccine or will it affect my pregnancy? – Eliza* ...</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active"><span>3</span></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_3 --> <div id="page_4" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active"><span>4</span></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="61"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=routine+AND+definition&pg=6&id=ED108629','ERIC'); return false;" href="https://eric.ed.gov/?q=routine+AND+definition&pg=6&id=ED108629"><span>OPSN: The <span class="hlt">IMS</span> COMSYS 1 and 2 Data Preprocessing System.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Yu, John</p> <p></p> <p>The Instructional Management System (<span class="hlt">IMS</span>) developed by the Southwest Regional Laboratory (SWRL) processes student and teacher-generated data through the use of an optical scanner that produces a magnetic tape (Scan Tape) for input to <span class="hlt">IMS</span>. A series of computer routines, OPSN, preprocesses the Scan Tape and prepares the data for transmission to the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED059096.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED059096.pdf"><span>Formative Evaluation of the Individualized Mathematics System (<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Frary, Robert B.</p> <p></p> <p>An evaluation of the first year of operation of the elementary part of the Individualized Mathematics System (<span class="hlt">IMS</span>) is reported in this document. The opening section describes the <span class="hlt">IMS</span> course, where re-usable workpages guide students to work individually, often using manipulative materials, to meet carefully defined objectives at nine levels. The…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026852','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026852"><span><span class="hlt">IMS</span> R and D program at Canada customs</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Pilon, Pierre; Mungham, Tony; Ng, Lay-Keow; Lawrence, Andre</p> <p>1995-01-01</p> <p>Over the last few years, Revenue Canada, in collaboration with Barringer Instruments Limited, has been involved in the development of a field-usable ion mobility spectrometer (<span class="hlt">IMS</span>) for the detection of drugs of abuse. This work has culminated in the manufacturing and commercialization by Barringer of the Ionscan 350 instruments, now in use by various law enforcement agencies worldwide. Although <span class="hlt">IMS</span> exhibits a very strong and distinctive response toward some nitrogen containing drugs, e.g., cocaine, like all separation techniques it has inherent limitations, namely moderate resolution and low chemical signal to noise ratio which may affect the reliability of <span class="hlt">IMS</span>-based drug detectors. A program is in place at the Laboratory and Scientific Services Directorate (LSSD) to investigate the applicability of various digital signal processing (DSP) techniques to <span class="hlt">IMS</span> output signals. The application of neural network techniques to overlapping <span class="hlt">IMS</span> peaks is presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998SPIE.3575..375H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998SPIE.3575..375H"><span>GC-<span class="hlt">IMS</span>: a technology for many applications</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Haley, Lawrence V.; Romeskie, Julian M.</p> <p>1998-12-01</p> <p>Fast GC (gas chromatography) - <span class="hlt">IMS</span> (ion mobility spectrometry) as a core technology is sufficiently flexible with respect to a broad range of chemical detection capabilities. The application of this dual technology can provide unique solutions in many operational environments. GC-<span class="hlt">IMS</span> is the next evolutionary step in the advancement of <span class="hlt">IMS</span> technology. Using the advantages of <span class="hlt">IMS</span> (i.e., small, high sensitivity, rugged, operates at atmospheric pressure, etc.) And the chemical selection capability of GC, this detector configuration can be customized to detect and identify explosives, ICAO markers, and narcotics. This paper will present a technical discussion on GC-<span class="hlt">IMS</span> and describe several commercial off the shelf (COTS) systems with potential application in many operating environments. Instruments include the Orion for explosives detection, Ariel for narcotics detection, Sirius for both explosives and narcotics detection, and NorthStar for handheld narcotics detection.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19920024179','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19920024179"><span>Isothermal aging of <span class="hlt">IM</span>7/8320 and <span class="hlt">IM</span>7/5260</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Martin, Roderick H.; Siochi, Emilie J.; Gates, Thomas S.</p> <p>1992-01-01</p> <p>Isothermal aging was conducted on two composite systems being considered as possible candidates for the next generation supersonic transport. The composite systems were <span class="hlt">IM</span>7/5260, a carbon/thermoset, and <span class="hlt">IM</span>7/8320, a carbon/amorphous thermoplastic. The materials were isothermally aged for a total of 5000 hours at 125 C and 175 C. These temperatures are approximately equivalent to the upper skin temperatures of an aircraft flying at Mach 2.0 and Mach 2.4, respectively. The variations of the following properties were determined as a function of aging time: weight loss, moduli, glass transition temperature, microcracking, and modulus and strength of a +/- 45 laminate. The difficulties and accuracy of strain measurements are also discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026867','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026867"><span>A digital boxcar integrator for <span class="hlt">IMS</span> spectra</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Cohen, Martin J.; Stimac, Robert M.; Wernlund, Roger F.; Parker, Donald C.</p> <p>1995-01-01</p> <p>When trying to detect or quantify a signal at or near the limit of detectability, it is invariably embeded in the noise. This statement is true for nearly all detectors of any physical phenomena and the limit of detectability, hopefully, occurs at very low signal-to-noise levels. This is particularly true of <span class="hlt">IMS</span> (Ion Mobility Spectrometers) spectra due to the low vapor pressure of several chemical compounds of great interest and the small currents associated with the ionic detection process. Gated Integrators and Boxcar Integrators or Averagers are designed to recover fast, repetitive analog signals. In a typical application, a time 'Gate' or 'Window' is generated, characterized by a set delay from a trigger or gate pulse and a certain width. A Gated Integrator amplifies and integrates the signal that is present during the time the gate is open, ignoring noise and interference that may be present at other times. Boxcar Integration refers to the practice of averaging the output of the Gated Integrator over many sweeps of the detector. Since any signal present during the gate will add linearly, while noise will add in a 'random walk' fashion as the square root of the number of sweeps, averaging N sweeps will improve the 'Signal-to-Noise Ratio' by a factor of the square root of N.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25419999','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25419999"><span>Thin layer chromatography-ion mobility spectrometry (TLC-<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ilbeigi, Vahideh; Tabrizchi, Mahmoud</p> <p>2015-01-06</p> <p>Ion mobility spectrometry (<span class="hlt">IMS</span>) is a fast and sensitive analytical method which operates at the atmospheric pressure. To enhance the capability of <span class="hlt">IMS</span> for the analysis of mixtures, it is often used with preseparation techniques, such as GC or HPLC. Here, we report for the first time the coupling of the thin-layer chromatography and <span class="hlt">IMS</span>. A variety of coupling schemes were tried that included direct electrospray from the TLC strip tip, indirect electrospray from a needle connected to the TLC strip, introducing the moving solvent into the injection port, and, the simplest way, offline introduction of scratched or cut pieces of strips into the <span class="hlt">IMS</span> injection port. In this study a special solvent tank was designed and the TLC strip was mounted horizontally where the solvent would flow down. A very small funnel right below the TLC tip collected the solvent and transferred it to a needle via a capillary tubing. Using the TLC-ESI-<span class="hlt">IMS</span> technique, acceptable separations were achieved for two component mixtures of morphine-papaverine and acridine-papaverine. A special injection port was designed to host the pieces cut off the TLC. The method was successfully used to identify each spot on the TLC by <span class="hlt">IMS</span> in a few seconds.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?direntryid=314570&subject=homeland%20security%20research&view=desc&sortby=pubdateyear&showcriteria=1&count=25&searchall='analytical%20methods'%20or%20'analytical%20method'%20or%20'method%20development'%20or%20'methods%20development'%20or%20'standardized%20analytical%20methods'%20or%20'sam'%20or%20%22selected%20analytical%20methods'&','PESTICIDES'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?direntryid=314570&subject=homeland%20security%20research&view=desc&sortby=pubdateyear&showcriteria=1&count=25&searchall='analytical%20methods'%20or%20'analytical%20method'%20or%20'method%20development'%20or%20'methods%20development'%20or%20'standardized%20analytical%20methods'%20or%20'sam'%20or%20%22selected%20analytical%20methods'&"><span>Development of a human-specific B. thetaiotaomicron <span class="hlt">IMS</span> ...</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>Immunomagnetic separation/adenosine triphosphate (<span class="hlt">IMS</span>/ATP) assays utilize paramagnetic beads and target-specific antibodies to isolate target organisms. Following isolation, adenosine tri-phosphate (ATP) is extracted from the target population and quantified. An inversely-coupled (Inv-<span class="hlt">IMS</span>/ATP)assay for detection of Bacteroides thetaiotaomicron was developed and applied for rapid detection of human-associated fecal contamination in surface waters in Baja California. Specificity of the assay was tested against challenge solutions of varying concentrations of dog, gull, horse and chicken feces, and a field validation survey of coastal and WWTP effluent water quality in Rosarito and Enseneda, Baja California was conducted. Inv <span class="hlt">IMS</span>/ATP measurements made shown to be specific and sensitive to human fecal contamination. At test concentrations of less than 1000 MPN ENT/100 mL, sensitivity and specificity of the assay both exceeded 80%. Moreover, the Inv-<span class="hlt">IMS</span>/ATP assay yielded measurements of viable B. thetaiotaomicron that were comparable to the HF183 human marker in complex surface waters impacted with both wastewater and runoff, and the Inv-<span class="hlt">IMS</span>/ATP assay was able to effectively differentiate between surface waters impacted with adequately and inadequately treated wastewater. The Inv-<span class="hlt">IMS</span>/ATP assays shows promise for rapid evaluation of recreational water quality in areas where access to more expensive methods is limited and in areas where water quality in unpredicta</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFM.S51C2692M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFM.S51C2692M"><span>Overview of <span class="hlt">IMS</span> infrasound station and engineering projects</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Marty, J.; Doury, B.; Kramer, A.; Martysevich, P.</p> <p>2015-12-01</p> <p>The Provisional Technical Secretariat (PTS) of the Comprehensive Nuclear-Test-Ban Treaty (CTBTO) has a continuous interest in enhancing its capability in acoustic source detection, localization and characterization. The infrasound component of the International Monitoring System (<span class="hlt">IMS</span>) constitutes the only worldwide ground-based infrasound network. It consists of sixty stations, among which forty-eight are already certified and continuously transmit data to the International Data Centre (IDC) in Vienna, Austria. Each infrasound station is composed of an array of infrasound sensors capable of measuring micro-pressure changes produced at ground level by infrasonic waves. The characteristics of infrasonic waves are computed in near real-time by IDC automatic detection software and are used as an input to IDC source categorization and localization algorithms. The PTS is continuously working towards the completion and sustainment of the <span class="hlt">IMS</span> infrasound network. The objective of this presentation is to review the main activities performed in the <span class="hlt">IMS</span> infrasound network over the last five years. This includes construction, installation, certification, major upgrade and revalidation activities. Major technology development projects to improve the reliability and robustness of <span class="hlt">IMS</span> infrasound stations as well as their compliance with <span class="hlt">IMS</span> Operational Manual requirements will also be presented. This includes advances in array geometry, wind noise reduction, system calibration, meteorological data as well as power and communication infrastructures. Finally the impact of all these changes on the overall detection capability of the <span class="hlt">IMS</span> infrasound network will be highlighted.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol2/pdf/CFR-2011-title40-vol2-sec51-352.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol2/pdf/CFR-2011-title40-vol2-sec51-352.pdf"><span>40 CFR 51.352 - Basic <span class="hlt">I/M</span> performance standard.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-07-01</p> <p>... 40 Protection of Environment 2 2011-07-01 2011-07-01 false Basic <span class="hlt">I/M</span> performance standard. 51.352... Requirements § 51.352 Basic <span class="hlt">I/M</span> performance standard. (a) Basic <span class="hlt">I/M</span> programs shall be designed and implemented... following model <span class="hlt">I/M</span> program inputs and local characteristics, such as vehicle mix and local fuel...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol2/pdf/CFR-2010-title40-vol2-sec51-352.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol2/pdf/CFR-2010-title40-vol2-sec51-352.pdf"><span>40 CFR 51.352 - Basic <span class="hlt">I/M</span> performance standard.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-07-01</p> <p>... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Basic <span class="hlt">I/M</span> performance standard. 51.352... Requirements § 51.352 Basic <span class="hlt">I/M</span> performance standard. (a) Basic <span class="hlt">I/M</span> programs shall be designed and implemented... following model <span class="hlt">I/M</span> program inputs and local characteristics, such as vehicle mix and local fuel...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009smlp.book..139D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009smlp.book..139D"><span>Grundlegende Steuerungsverfahren <span class="hlt">im</span> heterogenen Logistiknetz mit Kanban</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Dickmann, Eva; Dickmann, Philipp; Lödding, Hermann; Möller, Niklas; Rücker, Thomas; Schneider, Herfried M.; Zäh, Michael F.</p> <p></p> <p>In vielen Unternehmen werden heterogene (verschiedene) Steuerungen in einem abgestimmten Konzept kombiniert. Je nach Anwendungsfall und Rahmenbedingungen werden Kombinationen allgemein bekannter Steuerungen oder Steuerungsvarianten gemischt eingesetzt, um eine optimale Steuerung für unterschiedliche Fälle zu erreichen. Hierbei stehen neben den bekannten und weit verbreiteten Methoden, wie Material Requirements Planning (MRP) oder Kanban, auch weniger bekannte oder neue Methoden zur Auswahl, wie die Produktionssteuerung mit dezentraler, bestandsorientierter Fertigungsregelung (DBF). Kanban ist ein simples und effizientes Steuerungskonzept, das in der klassischen Form für spezifische einfache Anwendungsfälle umsetzbar ist. Hochentwickelte Steuerungsalgorithmen können helfen, komplexe Abläufe optimal abzubilden. Mit einer grundlegenden Vereinfachung der Abläufe kann allerdings in vielen Fällen ein wesentlich stärkerer und umfassender Verbesserungseffekt erzielt werden. Die wesentliche Fragestellung sollte folglich lauten: Warum ist der Ablauf nicht mit einer einfachen Steuerung wie Kanban abzubilden? Um die Vorteile des Konzepts auch in untypischen Bereichen anwenden zu können, sind jedoch verschiedene Varianten oder Kanban-ähnliche Steuerungsmethoden entstanden. Darüber hinaus sind in der Praxis hybride Steuerungen <span class="hlt">im</span> Einsatz, welche so kombiniert werden, dass die Zusammensetzung anspruchsvolle Eigenschaftsbilder noch exakt abbildet. In der Praxis basieren die Steuerungsentscheidungen nur zu einem kleinen Teil auf den eigentlichen Steuerungsalgorithmen, wie sie uns das MRP-System zur Verfügung stellt. Moderne Steuerungswelten" schließen alle relevanten Informationsquellen in eine heterogene Entscheidungsmatrix mit ein. Letztlich zählt nicht, ob die Entscheidung auf den Informationen aus dem MRP-System oder auf Softfacts basierend getroffen wurde, sondern nur, ob die Entscheidung erfolgreich war.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JAVSO..43..259Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JAVSO..43..259Z"><span><span class="hlt">IM</span> Normae: A Second T Pyx? (Abstract)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Patterson, J.; Monard, B.; Warhurst, P.; Myers, G.</p> <p>2015-12-01</p> <p>(Abstract only) T Pyx is the Galaxy's most famous recurrent nova, erupting to magnitude 6 about every 20 years. For nova hunters and variable-star observers generally, it should be quite easy to discover stars with similar properties. There are probably half a million CVs out to the distance of T Pyx, and most have an underlying structure similar to that of T Pyx: low-mass secondary, fairly massive white dwarf, short orbital period. But of these half million stars, there is no second T Pyx. The star is unique in another way: its orbital period is increasing on a timescale of 300,000 years. Like the proverbial bat out of hell. A 2002 nova eruption nominated a second star for this elite club: <span class="hlt">IM</span> Nor, a short-orbital-period (2.5 hours) star which previously erupted in 1920. We began a program of time-series photometry to track the shallow eclipses—to test for orbital period change, the other signature of T Pyx resemblance. By 2015 we found this effect: Porb increases on a timescale of 2 million years. Thus, the two stars appear to be blowing themselves apart on a timescale of roughly a million years. This could explain why the stars are so rare: because they are rapidly self-immolating. And that could happen because the classical-nova outburst overwhelms the low-mass secondaries that live in short-period CVs—leading to unstable mass transfer which quickly evaporates the secondary. This implies that all short-Porb classical novae should be "recurrent" (erupting on a timescale of decades). Greater attention to CP Pup (1942), RW UMi (1956), GQ Mus (1983), and V Per (1887) is definitely warranted.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20000096494&hterms=chromatography&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dchromatography','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20000096494&hterms=chromatography&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dchromatography"><span>Evaluation of Gas Chromatography/Mini-<span class="hlt">IMS</span> to Detect VOCs</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Limero, Thomas; Reese, Eric; Peters, Randy; James, John T.; Billica, Roger (Technical Monitor)</p> <p>1999-01-01</p> <p>The Toxicology Laboratory at Johnson Space Center (JSC) has pioneered the use of gas chromatography-ion mobility spectrometry (GC/<span class="hlt">IMS</span>) for measuring target volatile organic compounds (VOCs) aboard spacecraft. Graseby Dynamics, under contract to NASA/Wyle, has built several volatile organic analyzers (VOA) based on GC/<span class="hlt">IMS</span>. Foremost among these have been the volatile organic analyzer-risk mitigation unit and the two flight VOA units for International Space Station (ISS). The development and evaluation of these instruments has been chronicled through presentations at the International Conference on Ion Mobility Spectrometry over the past three years. As the flight VOA from Graseby is prepared for operation on ISS at JSC, it is time to begin evaluations of technologies for the next generation VOA, Although the desired instrument characteristics for the next generation unit are the same as the current unit, the requirements are much more stringent. As NASA looks toward future missions beyond Earth environs, a premium will be placed upon small, light, reliable, autonomous hardware. It is with these visions in mind that the JSC Toxicology Laboratory began a search for the next generation VOA. One technology that is a candidate for the next generation VOA is GC/<span class="hlt">IMS</span>. The recent miniaturization of <span class="hlt">IMS</span> technology permits it to compete with other, inherently small, technologies such as chip-sized sensor arrays. This paper will discuss the lessons learned from the VOA experience and how that has shaped the design of a potential second generation VOA based upon GC/<span class="hlt">IMS</span> technology. Data will be presented from preliminary evaluations of GC technology and the mini-<span class="hlt">IMS</span> when exposed to VOCs likely to be detected aboard spacecraft. Results from the evaluation of an integrated GC/mini-<span class="hlt">IMS</span> system will be shown if available.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/889413','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/889413"><span>Ion mobility spectrometer / mass spectrometer (<span class="hlt">IMS</span>-MS).</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Hunka Deborah Elaine; Austin, Daniel E.</p> <p>2005-07-01</p> <p>The use of Ion Mobility Spectrometry (<span class="hlt">IMS</span>) in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on <span class="hlt">IMS</span>-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-<span class="hlt">IMS</span> sensors (1700), ordnance detection (2500), and Fourier Transform <span class="hlt">IMS</span> technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400). Combining Ion Mobility Spectrometry (<span class="hlt">IMS</span>) with Mass Spectrometry (MS) is described. The <span class="hlt">IMS</span>-MS combination overcomes several limitations present in simple <span class="hlt">IMS</span> systems. Ion mobility alone is insufficient to identify an unknown chemical agent. Collision cross section, upon which mobility is based, is not sufficiently unique or predictable a priori to be able to make a confident peak assignment unless the compounds present are already identified. Molecular mass, on the other hand, is much more readily interpreted and related to compounds. For a given compound, the molecular mass can be determined using a pocket calculator (or in one's head) while a reasonable value of the cross-section might require hours of computation time. Thus a mass spectrum provides chemical specificity and identity not accessible in the mobility spectrum alone. In addition, several advanced mass spectrometric methods, such as tandem MS, have been extensively developed for the purpose of molecular identification. With an appropriate mass spectrometer connected to an ion mobility spectrometer, these advanced identification methods become available, providing greater characterization capability.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1126945','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1126945"><span>Ion Mobility Spectrometer / Mass Spectrometer (<span class="hlt">IMS</span>-MS).</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Hunka, Deborah E; Austin, Daniel</p> <p>2005-10-01</p> <p>The use of Ion Mobility Spectrometry (<span class="hlt">IMS</span>)in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on <span class="hlt">IMS</span>-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-<span class="hlt">IMS</span> sensors (1700), ordnance detection (2500), and Fourier Transform <span class="hlt">IMS</span> technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400).Combining Ion Mobility Spectrometry (<span class="hlt">IMS</span>) with Mass Spectrometry (MS)The <span class="hlt">IMS</span>-MS combination overcomes several limitations present in simple <span class="hlt">IMS</span> systems. Ion mobility alone is insufficient to identify an unknown chemical agent. Collision cross section, upon which mobility is based, is not sufficiently unique or predictable a priori to be able to make a confident peak assignment unless the compounds present are already identified. Molecular mass, on the other hand, is much more readily interpreted and related to compounds. For a given compound, the molecular mass can be determined using a pocket calculator (or in one's head) while a reasonable value of the cross-section might require hours of computation time. Thus a mass spectrum provides chemical specificity and identity not accessible in the mobility spectrum alone. In addition, several advanced mass spectrometric methods, such as tandem MS, have been extensively developed for the purpose of molecular identification. With an appropriate mass spectrometer connected to an ion mobility spectrometer, these advanced identification methods become available, providing greater characterization capability.3 AcronymsIMSion mobility spectrometryMAAMaterial Access AreaMSmass spectrometryoaTOForthogonal acceleration time</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24156877','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24156877"><span>Are <span class="hlt">IM</span> injections <span class="hlt">IM</span> in obese and overweight females? A study in injection technique.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Palma, Sara; Strohfus, Pamela</p> <p>2013-11-01</p> <p>If given incorrectly, intramuscular injections may result in poor absorption of drug, reduced drug effectiveness, or irritation to surrounding tissues. In this study, <span class="hlt">IM</span> injection techniques were observed and documented for needle length, injection site, needle insertion, and stretching or bunching of the skin during injection in a population of adult females. The patients' weights and BMIs were recorded to determine the amount of subcutaneous fat at the injection site. In 22 patients of varied weights, 90% of injections were given within current Advisory Committee on Immunization Practice (ACIP) guidelines in normal and underweight patients, and 17% were given within ACIP guidelines in overweight and obese patients. The study concluded that the needle length used is often too short in overweight and obese individuals. © 2013.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19760008130','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19760008130"><span><span class="hlt">IMS</span>/Satellite Situation Center report. Special <span class="hlt">IMS</span> periods for 1976</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1975-01-01</p> <p>Special International Magnetospheric Study (<span class="hlt">IMS</span>) Satellite Periods selected at times when two or more satellites are expected to be in interesting regions of the magnetosphere simultaneously are described. Data are presented to aid in defining a program of magnetospheric observations which emphasizes coordinated measurements of satellites, rockets, balloons, aircraft, and ground-based stations. The position is given of currently operating high altitude spacecraft in the Geocentric Solar Ecliptic, Geocentric Solar Magnetospheric, and Solar Magnetic coordinate systems to determine their passage through the bow shock, the magnetopause, the cusp, or the neutral sheet region. Information on the synchronous and low altitude spacecraft and experiments are included in tabular form along with a tabular summary of all the rocket, balloon, and aircraft campaigns in 1976.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026859','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026859"><span>Direct analysis of organic priority pollutants by <span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Giam, C. S.; Reed, G. E.; Holliday, T. L.; Chang, L.; Rhodes, B. J.</p> <p>1995-01-01</p> <p>Many routine methods for monitoring of trace amounts of atmospheric organic pollutants consist of several steps. Typical steps are: (1) collection of the air sample; (2) trapping of organics from the sample; (3) extraction of the trapped organics; and (4) identification of the organics in the extract by GC (gas chromatography), HPLC (High Performance Liquid Chromatography), or MS (Mass Spectrometry). These methods are often cumbersome and time consuming. A simple and fast method for monitoring atmospheric organics using an <span class="hlt">IMS</span> (Ion Mobility Spectrometer) is proposed. This method has a short sampling time and does not require extraction of the organics since the sample is placed directly in the <span class="hlt">IMS</span>. The purpose of this study was to determine the responses in the <span class="hlt">IMS</span> to organic 'priority pollutants'. Priority pollutants including representative polycyclic aromatic hydrocarbons (PAHs), phthalates, phenols, chlorinated pesticides, and polychlorinated biphenyls (PCB's) were analyzed in both the positive and negative detection mode at ambient atmospheric pressure. Detection mode and amount detected are presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19720012322','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19720012322"><span>Information management system study results. Volume 1: <span class="hlt">IMS</span> study results</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1971-01-01</p> <p>The information management system (<span class="hlt">IMS</span>) special emphasis task was performed as an adjunct to the modular space station study, with the objective of providing extended depth of analysis and design in selected key areas of the information management system. Specific objectives included: (1) in-depth studies of <span class="hlt">IMS</span> requirements and design approaches; (2) design and fabricate breadboard hardware for demonstration and verification of design concepts; (3) provide a technological base to identify potential design problems and influence long range planning (4) develop hardware and techniques to permit long duration, low cost, manned space operations; (5) support SR&T areas where techniques or equipment are considered inadequate; and (6) permit an overall understanding of the <span class="hlt">IMS</span> as an integrated component of the space station.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active"><span>4</span></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_4 --> <div id="page_5" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active"><span>5</span></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="81"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19820055778&hterms=review+international+studies&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dreview%2Binternational%2Bstudies','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19820055778&hterms=review+international+studies&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dreview%2Binternational%2Bstudies"><span>Current status of <span class="hlt">IMS</span> plasma wave research. [International Magnetospheric Study</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Anderson, R. R.</p> <p>1982-01-01</p> <p>The present investigation is concerned with a review of the status of magnetospheric plasma wave science as a result of the International Magnetospheric Study (<span class="hlt">IMS</span>). The presence of an international effort has supported the development and completion of the numerous magnetospheric science spacecraft launched during the <span class="hlt">IMS</span>, including GEOS, ISEE, and EXOS B. Ground-based VLF observations are considered along with coordinated ground-based and satellite observations. During the <span class="hlt">IMS</span>, plasma wave research using satellite data has covered a wide range of subjects. Attention is given to magnetospheric electrostatic emissions, magnetospheric electromagnetic plasma waves, continuum radiation, auroral kilometric radiation, auroral zone plasma waves, plasma waves in the magnetosheath and near the mangetopause, and plasma waves at the bow shock.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/419518','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/419518"><span>Robust sliding mode continuous control of an <span class="hlt">IM</span> drive</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Jezernik, K.; Hren, A.; Drevensek, D.</p> <p>1995-12-31</p> <p>A control approach for robust trajectory tracking of <span class="hlt">IM</span> servodrive based on the variable structure systems (VSS) is described. A new discrete-time control algorithm has been developed by combining VSS and Lyapunov design. It possesses all the good properties of the sliding mode and avoids the unnecessary discontinuity of the control input, thus eliminating chattering which has been considering as serious obstacles for applications of VSS. A unified control approach for current, torque and motion control based on the discrete-time sliding mode for application in indirect vector control of an <span class="hlt">IM</span> drive is developed. The sliding mode approach can be applied to the control of an <span class="hlt">Im</span> drive due to the replacement of the hysteresis controller with widely used PWM technique. All the theoretical issues are verified by experiment. The experimental system consists of a transputer and a microcontroller, thus allowing parallel processing.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28399894','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28399894"><span>Preoperative imatinib mesylate (<span class="hlt">IM</span>) for huge gastrointestinal stromal tumors (GIST).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tang, Sumin; Yin, Yuan; Shen, Chaoyong; Chen, Jiaju; Yin, Xiaonan; Zhang, Bo; Yao, Yuqin; Yang, Jinliang; Chen, Zhixin</p> <p>2017-04-11</p> <p>Preoperative imatinib mesylate (<span class="hlt">IM</span>) treatment has not yet been standardized. Here, we aim to further explore such therapy on patients with gastrointestinal stromal tumors (GIST) retrospectively. Patients experiencing preoperative <span class="hlt">IM</span> were identified from January 2009 to February 2015. A total of 28 GIST patients were identified. The patients received preoperative <span class="hlt">IM</span> treatment for a median length of 13.5 months, ranging from 5 to 37 months. PR and SD were observed in 24 (85.7%) and 4 (15.3%) patients, respectively. The tumor shrinkage occurred predominantly within 6 to 12 months, and slight tumor shrinkage could be observed after 12 months in certain patients. Nineteen patients (67.9%) received surgery, and R0 resection was acquired in 18 (94.7%) patients. The initial mean maximum diameter was 10.5 (5.2 to 19.0) cm and decreased to 5.9 (2.7 to 19.0) cm after preoperative treatment with a median length of 12 (ranging from 5 to 36) months (P < 0.001) in patients receiving operations. Three in 7 cases of rectum GIST underwent abdominoperineal resection, and four others adopted sphincter-sparing resection. Partial gastrectomy was performed in four patients. <span class="hlt">IM</span> prior to surgery can effectively prevent tumor rupture and facilitate surgery with low surgical morbidity for GIST patients. Tumor shrinkage following <span class="hlt">IM</span> occurred predominantly within 6 to 12 months, and slight tumor shrinkage could be observed after 12 months in certain patients. In selected patients, prolonged exposure to <span class="hlt">IM</span> is seemingly advisable under close radiological surveillance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28365709','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28365709"><span>Therapie des metastasierten kastrationsresistenten Prostatakarzinoms mit Abirateronacetat <span class="hlt">im</span> klinischen Alltag.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wolff, Johannes Maria</p> <p>2017-01-01</p> <p>Abirateronacetat, das in Kombination mit Prednison/Prednisolon verabreicht wird, spielt eine wichtige Rolle in der Therapie des metastasierten kastrationsresistenten Prostatakarzinoms. <span class="hlt">Im</span> Folgenden wurden besondere Aspekte der Therapie <span class="hlt">im</span> klinischen Alltag zusammengestellt. Sie betreffen unter anderem die Dosierung - auch vor dem Hintergrund der Markteinführung einer neuen Formulierung von Abirateronacetat. Hinzu kommt die Verträglichkeit, vor allem in Bezug auf kardiovaskuläre und Kortikoid-bedingte Nebenwirkungen. Des Weiteren werden Kriterien genannt, nach denen die Therapie nicht zu früh umgestellt werden sollte. © 2017 S. Karger GmbH, Freiburg.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3718353','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3718353"><span><span class="hlt">Im</span>Pact Test-Retest Reliability: Reliably Unreliable?</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Resch, Jacob; Driscoll, Aoife; McCaffrey, Noel; Brown, Cathleen; Ferrara, Michael S.; Macciocchi, Stephen; Baumgartner, Ted; Walpert, Kimberly</p> <p>2013-01-01</p> <p>Context: Computerized neuropsychological testing is commonly used in the assessment and management of sport-related concussion. Even though computerized testing is widespread, psychometric evidence for test-retest reliability is somewhat limited. Additional evidence for test-retest reliability is needed to optimize clinical decision making after concussion. Objective: To document test-retest reliability for a commercially available computerized neuropsychological test battery (<span class="hlt">Im</span>PACT) using 2 different clinically relevant time intervals. Design: Cross-sectional study. Setting: Two research laboratories. Patients or Other Participants: Group 1 (n = 46) consisted of 25 men and 21 women (age = 22.4 ± 1.89 years). Group 2 (n = 45) consisted of 17 men and 28 women (age = 20.9 ± 1.72 years). Intervention(s): Both groups completed <span class="hlt">Im</span>PACT forms 1, 2, and 3, which were delivered sequentially either at 1-week intervals (group 1) or at baseline, day 45, and day 50 (group 2). Group 2 also completed the Green Word Memory Test (WMT) as a measure of effort. Main Outcome Measures: Intraclass correlation coefficients (ICCs) were calculated for the composite scores of <span class="hlt">Im</span>PACT between time points. Repeated-measures analysis of variance was used to evaluate changes in <span class="hlt">Im</span>PACT and WMT results over time. Results: The ICC values for group 1 ranged from 0.26 to 0.88 for the 4 <span class="hlt">Im</span>PACT composite scores. The ICC values for group 2 ranged from 0.37 to 0.76. In group 1, <span class="hlt">Im</span>PACT classified 37.0% and 46.0% of healthy participants as impaired at time points 2 and 3, respectively. In group 2, <span class="hlt">Im</span>PACT classified 22.2% and 28.9% of healthy participants as impaired at time points 2 and 3, respectively. Conclusions: We found variable test-retest reliability for <span class="hlt">Im</span>PACT metrics. Visual motor speed and reaction time demonstrated greater reliability than verbal and visual memory. Our current data support a multifaceted approach to concussion assessment using clinical examinations, symptom reports, cognitive</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009IEITI..92..937B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009IEITI..92..937B"><span>A Trust Ranking Method to Prevent <span class="hlt">IM</span> Spam</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bi, Jun</p> <p></p> <p>The problem of <span class="hlt">IM</span> (Instant Messaging) SPAM, also known as SPIM, has become a challenge in recent years. The current anti-SPAM methods are not quite suitable for SPIM because of the differences in system infrastructures and characteristics between <span class="hlt">IM</span> and email service. In order to effectively eliminate SPIM, we propose a trust ranking method in this paper. The mechanism to build up reputation network, global reputation and local trust ranking algorithms, reputation management, and SPIM filtering methods are presented. The experiments under five treat modes and algorithms enhancement are also introduced. The experiment shows that the proposed method is resilient to deal with SPIM attacks under several threat models.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19830035059&hterms=periods+attention&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dperiods%2Battention','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19830035059&hterms=periods+attention&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dperiods%2Battention"><span>Data from ISEE-3 for the <span class="hlt">IMS</span> period</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Von Rosenvinge, T. T.</p> <p>1982-01-01</p> <p>The International Sun-Earth Explorer (ISEE) Project represents a joint effort between the European Space Agency and NASA. The primary objective of the project is the study of the outer magnetosphere. A review is presented concerning the data available from ISEE-3 up to the end of the International Magnetospheric Study (<span class="hlt">IMS</span>) period (December 31, 1979), taking into account the approaches used to obtain the data. Attention is given to the ISEE-3 as an upstream monitor, ISEE-3 an an observer of the magnetosphere, aspects of ISEE-3 data availability, questions regarding the data link, and the definitive orbit position of ISEE-3 throughout the <span class="hlt">IMS</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007ams..book..219S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007ams..book..219S"><span>Hinderniserkennung und -verfolgung mit einer PMD-kamera <span class="hlt">im</span> automobil</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger</p> <p></p> <p>Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden <span class="hlt">im</span> Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse <span class="hlt">im</span> Fahrbereich des Automobils.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015CQGra..32v4021B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015CQGra..32v4021B"><span>VLBI for Gravity Probe B: the guide star, <span class="hlt">IM</span> Pegasi</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bartel, N.; Bietenholz, M. F.; Lebach, D. E.; Ransom, R. R.; Ratner, M. I.; Shapiro, I. I.</p> <p>2015-11-01</p> <p>We review the radio very long baseline interferometry (VLBI) observations of the guide star, <span class="hlt">IM</span> Peg, and three compact extragalactic reference sources, made in support of the NASA/Stanford gyroscope relativity mission, Gravity Probe B (GP-B). The main goal of the observations was the determination of the proper motion of <span class="hlt">IM</span> Peg relative to the distant Universe. VLBI observations made between 1997 and 2005 yield a proper motion of <span class="hlt">IM</span> Peg of -20.83 ± 0.09 mas yr-1 in α and -27.27 ± 0.09 mas yr-1 in δ in a celestial reference frame of extragalactic radio galaxies and quasars virtually identical to the International Celestial Reference Frame 2 (ICRF2). They also yield a parallax for <span class="hlt">IM</span> Peg of 10.37 ± 0.07 mas, corresponding to a distance of 96.4 ± 0.7 pc. The uncertainties are standard errors with statistical and estimated systematic contributions added in quadrature. These results met the pre-launch requirements of the GP-B mission to not discernibly degrade the estimates of the geodetic and frame-dragging effects.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=cone&pg=6&id=EJ886287','ERIC'); return false;" href="https://eric.ed.gov/?q=cone&pg=6&id=EJ886287"><span>The Education of Children in <span class="hlt">Im</span>/Migrant Families</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Arzubiaga, Angela E.; Nogueron, Silvia C.; Sullivan, Amanda L.</p> <p>2009-01-01</p> <p>The numbers of <span class="hlt">im</span>/migrant children in schools have increased throughout the world. The principal receiving areas are North America, Western Europe, the Persian Gulf, Asia and the Pacific, and the Southern Cone of South America. In the United States, one out of every four children younger than the age of 8 lives in a family where at least one…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1813072W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1813072W"><span>Static corrections for enhanced signal detection at <span class="hlt">IMS</span> seismic arrays</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wilkins, Neil; Wookey, James; Selby, Neil</p> <p>2016-04-01</p> <p>Seismic monitoring forms an important part of the International Monitoring System (<span class="hlt">IMS</span>) for verifying the Comprehensive nuclear Test Ban Treaty (CTBT). Analysis of seismic data can be used to discriminate between nuclear explosions and the tens of thousands of natural earthquakes of similar magnitude that occur every year. This is known as "forensic seismology", and techniques include measuring the P-to-S wave amplitude ratio, the body-to-surface wave magnitude ratio (mb/Ms), and source depth. Measurement of these seismic discriminants requires very high signal-to-noise ratio (SNR) data, and this has led to the development and deployment of seismic arrays as part of the <span class="hlt">IMS</span>. Array processing methodologies such as stacking can be used, but optimum SNR improvement needs an accurate estimate of the arrival time of the particular seismic phase. To enhance the imaging capability of <span class="hlt">IMS</span> arrays, we aim to develop site-specific static corrections to the arrival time as a function of frequency, slowness and backazimuth. Here, we present initial results for the <span class="hlt">IMS</span> TORD array in Niger. Vespagrams are calculated for various events using the F-statistic to clearly identify seismic phases and measure their arrival times. Observed arrival times are compared with those predicted by 1D and 3D velocity models, and residuals are calculated for a range of backazimuths and slownesses. Finally, we demonstrate the improvement in signal fidelity provided by these corrections.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED108595.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED108595.pdf"><span>Criteria Underlying the Formation of Alternative <span class="hlt">IMS</span> Configurations.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dave, Ashok</p> <p></p> <p>To assist the formation of <span class="hlt">IMS</span> (Instructional Management System) configurations, three categories of characteristics are developed and explained. Categories 1 and 2 emphasize automation, and the necessity of forming workable configurations to carry out instructional management for Southwest Regional Laboratory developed instructional and/or…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AAN...567....1W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AAN...567....1W"><span><span class="hlt">IM</span> Nor monitoring requested for HST COS observations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Waagen, Elizabeth O.</p> <p>2017-02-01</p> <p>Dr. Ed Sion (Villanova University) and colleagues have requested AAVSO observers' assistance in monitoring the symbiotic-type recurrent nova <span class="hlt">IM</span> Nor in support of observations with the Hubble Space Telescope Cosmic Origins Spectrograph scheduled for 2017 February 13 - 17 UT. These observations are part of a study on short orbital period recurrent novae as Supernovae Type Ia progenitors. It is essential to know 24 hours prior to the HST COS observations that <span class="hlt">IM</span> Nor is not in outburst, in order to protect the instrumentation. Also, photometry is needed throughout the HST window to insure knowledge of the brightness of the system. Observers are asked to monitor <span class="hlt">IM</span> Nor with nightly snapshot images (V preferred) from now through February 20, and to report their observations promptly. It will be especially important to know the brightness of <span class="hlt">IM</span> Nor each night through February 17 UT. Finder charts with sequence may be created using the AAVSO Variable Star Plotter (https://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1096247.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1096247.pdf"><span>Vo<span class="hlt">IM</span>-Mediated Cooperative Tasks for English Language Learners</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Chinnery, George M.</p> <p>2008-01-01</p> <p>The use of telephones--even mobile phones--in language learning is not unique (see Chinnery 2006). The literature is also The literature is also replete with imaginative ideas on how to apply Internet chat software like instant messengers (<span class="hlt">IM</span>) to language learning. A more recent technological development of use to educators is Internet telephony,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ922262.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ922262.pdf"><span>The (<span class="hlt">Im</span>)possibility of the Project: Radford Address</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Green, Bill</p> <p>2010-01-01</p> <p>In this address, the author engages both with the possibility "and" the impossibility of the educational project--and suggests something of what it means to say this. His presentation is specifically addressed to the theme of the (<span class="hlt">im</span>)possibility of the educational project. He draws from philosophy, literature, psychoanalysis and history,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA533348','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA533348"><span>Synchronization of <span class="hlt">IM</span> and HC: The Navy Perspective</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2010-07-01</p> <p>Confidential letter to Admiral R.L.J. Long, Vice Chief of Naval Operations dated 27 February 1979. [2] CNO Memo Ser : 987/239915 dated 22 August 1979...Oriskany (1966) <span class="hlt">IM</span> can save lives and resources. Bien -Hoa Air Base, Vietnam (1965) Ammunition train explosion, Roseville, CA. (1973) Bomb explosion</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=gulf+AND+states&pg=7&id=EJ886287','ERIC'); return false;" href="http://eric.ed.gov/?q=gulf+AND+states&pg=7&id=EJ886287"><span>The Education of Children in <span class="hlt">Im</span>/Migrant Families</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Arzubiaga, Angela E.; Nogueron, Silvia C.; Sullivan, Amanda L.</p> <p>2009-01-01</p> <p>The numbers of <span class="hlt">im</span>/migrant children in schools have increased throughout the world. The principal receiving areas are North America, Western Europe, the Persian Gulf, Asia and the Pacific, and the Southern Cone of South America. In the United States, one out of every four children younger than the age of 8 lives in a family where at least one…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006okop.book.....N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006okop.book.....N"><span>Ökophysik: Plaudereien über das Leben auf dem Land, <span class="hlt">im</span> Wasser und in der Luft</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Nachtigall, W.</p> <p></p> <p>Prof. em. Dr. rer. nat. Werner Nachtigall, geb. 1934, war als Zoophysiologe und Biophysiker Leiter des Zoologischen Instituts der Universität des Saarlandes in Saarbrücken. In Forschung und Ausbildung hat er sich insbesondere mit Aspekten der Technischen Biologie und Bionik befasst und mit seinen Forschergruppen viele Basisdaten insbesondere zur Ökologie, Physiologie und Physik des Fliegens und Schwimmens aber auch zur Stabilität beispielsweise der Gräser erarbeitet. Lebewesen überraschen immer wieder durch <span class="hlt">ihre</span> "Biodiversität", <span class="hlt">ihre</span> hochspezifischen Ausgestaltungen und Anpassungen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010hale.book...59T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010hale.book...59T"><span>Regelungen <span class="hlt">im</span> Verkehr mit Lebensmitteln und Bedarfsgegenständen in Deutschland</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Thomas, Gundula; Freund, Astrid; Gründig, Friedrich</p> <p></p> <p><span class="hlt">Im</span> Zuge der Globalisierung von Produktion und Handel ändert sich auch der Charakter der Vorschriften <span class="hlt">im</span> Lebensmittelrecht. Zunehmend treten internationale Rechtsbestimmungen, Abkommen, Standards und andere Normen an die Stelle nationaler Regelungen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=integrated+AND+systems&pg=7&id=EJ1112654','ERIC'); return false;" href="http://eric.ed.gov/?q=integrated+AND+systems&pg=7&id=EJ1112654"><span>Flexible Authoring and Delivery of Online Courses Using <span class="hlt">IMS</span> Learning Design</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hermans, Henry; Janssen, José; Koper, Rob</p> <p>2016-01-01</p> <p>Since the publication of the <span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span> LD) specification in 2003, many initiatives have been undertaken to build authoring tools that are simple enough to be used by non-technical instructors and teachers. <span class="hlt">IMS</span> LD's technical complexity is believed to be a major burden for the adoption of the specification. We have developed a new…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active"><span>5</span></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_5 --> <div id="page_6" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="101"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=enough&id=EJ1112654','ERIC'); return false;" href="https://eric.ed.gov/?q=enough&id=EJ1112654"><span>Flexible Authoring and Delivery of Online Courses Using <span class="hlt">IMS</span> Learning Design</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hermans, Henry; Janssen, José; Koper, Rob</p> <p>2016-01-01</p> <p>Since the publication of the <span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span> LD) specification in 2003, many initiatives have been undertaken to build authoring tools that are simple enough to be used by non-technical instructors and teachers. <span class="hlt">IMS</span> LD's technical complexity is believed to be a major burden for the adoption of the specification. We have developed a new…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=virtual+AND+Library&pg=5&id=EJ867004','ERIC'); return false;" href="http://eric.ed.gov/?q=virtual+AND+Library&pg=5&id=EJ867004"><span>Choosing the Right Free <span class="hlt">IM</span> Providers and Clients for Your Library</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Izenstark, Amanda K.</p> <p>2009-01-01</p> <p>With virtual library services increasing, public services librarians may find themselves with questions such as: What instant messaging services (<span class="hlt">IM</span>) are available? Which <span class="hlt">IM</span> service would best suit my patrons' needs? Which <span class="hlt">IM</span> service best suits my library's technology profile? This column describes the features and functionality of major instant…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=%22reference+services%22+AND+evaluation&pg=3&id=EJ867004','ERIC'); return false;" href="https://eric.ed.gov/?q=%22reference+services%22+AND+evaluation&pg=3&id=EJ867004"><span>Choosing the Right Free <span class="hlt">IM</span> Providers and Clients for Your Library</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Izenstark, Amanda K.</p> <p>2009-01-01</p> <p>With virtual library services increasing, public services librarians may find themselves with questions such as: What instant messaging services (<span class="hlt">IM</span>) are available? Which <span class="hlt">IM</span> service would best suit my patrons' needs? Which <span class="hlt">IM</span> service best suits my library's technology profile? This column describes the features and functionality of major instant…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22030064','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22030064"><span>Usability test of the <span class="hlt">Im</span>PRO, computer-based procedure system</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Jung, Y.; Lee, J.</p> <p>2006-07-01</p> <p><span class="hlt">Im</span>PRO is a computer based procedure in both flowchart and success logic tree. It is evaluated on the basis of computer based procedure guidelines. It satisfies most requirements such as presentations and functionalities. Besides, SGTR has been performed with <span class="hlt">Im</span>PRO to evaluate reading comprehension and situation awareness. <span class="hlt">Im</span>PRO is a software engine which can interpret procedure script language, so that <span class="hlt">Im</span>PRO is reliable by nature and verified with formal method. One bug, however, had hidden one year after release, but it was fixed. Finally backup paper procedures can be prepared on the same format as VDU in case of <span class="hlt">Im</span>PRO failure. (authors)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25952141','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25952141"><span><span class="hlt">IM</span>30 triggers membrane fusion in cyanobacteria and chloroplasts.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hennig, Raoul; Heidrich, Jennifer; Saur, Michael; Schmüser, Lars; Roeters, Steven J; Hellmann, Nadja; Woutersen, Sander; Bonn, Mischa; Weidner, Tobias; Markl, Jürgen; Schneider, Dirk</p> <p>2015-05-08</p> <p>The thylakoid membrane of chloroplasts and cyanobacteria is a unique internal membrane system harbouring the complexes of the photosynthetic electron transfer chain. Despite their apparent importance, little is known about the biogenesis and maintenance of thylakoid membranes. Although membrane fusion events are essential for the formation of thylakoid membranes, proteins involved in membrane fusion have yet to be identified in photosynthetic cells or organelles. Here we show that <span class="hlt">IM</span>30, a conserved chloroplast and cyanobacterial protein of approximately 30 kDa binds as an oligomeric ring in a well-defined geometry specifically to membranes containing anionic lipids. Triggered by Mg(2+), membrane binding causes destabilization and eventually results in membrane fusion. We propose that <span class="hlt">IM</span>30 establishes contacts between internal membrane sites and promotes fusion to enable regulated exchange of proteins and/or lipids in cyanobacteria and chloroplasts.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/785123','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/785123"><span>QUARTERLY TECHNICAL REPORT FOR IN-MINE (<span class="hlt">IM</span>) SYSTEM</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zvi H. Meiksin</p> <p>2001-07-01</p> <p>A circuit that had been earlier lab-tested to eliminate multi-antenna interference in the In-mine (<span class="hlt">IM</span>) system was fabricated, implemented and tested successfully in a system setting. An adaptive, tracking comb-filter for the through-the-earth (TTE) communications system was designed and implemented. This resulted in noticeable noise reduction. Studies for multi-channel transmission have begun.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009ssw..book..175P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009ssw..book..175P"><span>Expertise bewerben und finden <span class="hlt">im</span> Social Semantic Web</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Polleres, Axel; Mochol, Malgorzata</p> <p></p> <p><span class="hlt">Im</span> vorliegenden Beitrag diskutieren wir Rahmenbedingungen zur Kombination, Wiederverwendung und Erweiterung bestehender RDFVokabulare <span class="hlt">im</span> Social Semantic Web. Hierbei konzentrieren wir uns auf das Anwendungsszenario des Auffindens und Bewerbens von Experten <span class="hlt">im</span> Web oder Intranet. Wir präsentieren, wie RDF-Vokabulare einerseits und de facto Standardformate andererseits, die von täglich verwendeten Applikationen benutzt werden (z. B. vCard, iCal oder Dublin Core), kombiniert werden können, um konkrete Anwendungsfälle der Expertensuche und zum Management von Expertise zu lösen. Unser Fokus liegt darauf aufzuzeigen, dass für praktische Anwendungsszenarien nicht notwendigerweise neue Ontologien entwickelt werden müssen, sondern der Schlüssel vielmehr in der Integration von bestehenden, weit verbreiteten und sich ergänzenden Formaten zu einem kohärenten Netzwerk von Ontologien liegt. Dieser Ansatz garantiert sowohl direkte Anwendbarkeit von als auch niedrige Einstiegsbarrieren in Semantic Web-Technologien sowie einfache Integrierbarkeit in bestehende Applikationen. Die <span class="hlt">im</span> Web verfügbaren und verwendeten RDFFormate decken zwar einen großen Bereich der Aspekte zur Beschreibung von Personen und Expertisen ab, zeigen aber auch signifikante Überlappungen. Bisher gibt es wenig systematische Ansätze, um diese Vokabulare zu verbinden, sei es in Form von allgemeingültigen Praktiken, die definieren, wann welches Format zu benutzen ist, oder in Form von Regeln, die Überlappungen zwischen einzelnen Formaten formalisieren. Der vorliegende Artikel analysiert, wie bestehende Formate zur Beschreibung von Personen, Organisationen und deren Expertise kombiniert und, wo nötig, erweitert werden können. Darüber hinaus diskutieren wir Regelsprachen zur Beschreibung von Formatüberlappungen sowie deren praktische Verwendbarkeit zur Erstellung eines Ontologie-Netzwerks zur Beschreibung von Experten.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA471966','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA471966"><span>Information Management (<span class="hlt">IM</span>) Strategic Plan. Version 2.0</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1999-10-01</p> <p>commercial standards facilitate outsourcing of activities where appropriate. People routinely telecommute , saving office space and reducing impacts on... people and embodies the principles of a “learning organization”. The <span class="hlt">IM</span> community, working in partnership with its customers, has redesigned how it does...wide perspective to realize our shared vision for the future. We must become a learning organization, work as a team, and empower people to achieve</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008AGUFM.S13E..06L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008AGUFM.S13E..06L"><span>Assessing the detection capability of the global <span class="hlt">IMS</span> infrasound network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Le Pichon, A.; Vergoz, J.; Brachet, N.; Ceranna, L.; Green, D.; Evers, L.</p> <p>2008-12-01</p> <p>A global scale analysis based on available detection lists for all operating <span class="hlt">IMS</span> infrasound stations confirms that the primary factor controlling signal detectability is the seasonal variability of the stratospheric wind circulation. At most arrays, near %80 of the detections in the 0.2 to 2 Hz bandpass are associated with propagation downwind of the dominant wind direction. The seasonal transition in the bearings and number of detections between easterly and westerly directions is presented. The observed detection capability of the <span class="hlt">IMS</span> network is compared to the predicted one using near-real time atmospheric updates and station- dependent wind noise models. The influence of individual model parameters on the network performance is systematically assessed. At frequencies of interest for detecting atmospheric explosions (0.2 to 2 Hz), the simulations predict that explosions equivalent to ~500 t of TNT would be detected by at least two stations of the full <span class="hlt">IMS</span> network at any time of the year. Comprehensive ground-truth databases provide a statistical approach for evaluating the potential of infrasound monitoring. Accidental explosions are analysed and used here as benchmark for validating the calculated threshold maps. Such studies would help to optimize the siting of infrasound arrays with respect to both the number and configuration in order to monitor infrasonic sources of interest. They are an important step to enable a successful monitoring regime for atmospheric or surface events to act as an effective verification tool in any future enforcement of the CTBT.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/877054','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/877054"><span><span class="hlt">Im</span>SET: Impact of Sector Energy Technologies</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Roop, Joseph M.; Scott, Michael J.; Schultz, Robert W.</p> <p>2005-07-19</p> <p>This version of the Impact of Sector Energy Technologies (<span class="hlt">Im</span>SET) model represents the ''next generation'' of the previously developed Visual Basic model (<span class="hlt">Im</span>BUILD 2.0) that was developed in 2003 to estimate the macroeconomic impacts of energy-efficient technology in buildings. More specifically, a special-purpose version of the 1997 benchmark national Input-Output (I-O) model was designed specifically to estimate the national employment and income effects of the deployment of Office of Energy Efficiency and Renewable Energy (EERE) -developed energy-saving technologies. In comparison with the previous versions of the model, this version allows for more complete and automated analysis of the essential features of energy efficiency investments in buildings, industry, transportation, and the electric power sectors. This version also incorporates improvements in the treatment of operations and maintenance costs, and improves the treatment of financing of investment options. <span class="hlt">Im</span>SET is also easier to use than extant macroeconomic simulation models and incorporates information developed by each of the EERE offices as part of the requirements of the Government Performance and Results Act.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/127824','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/127824"><span>'Immobile' (<span class="hlt">im</span>), a recessive lethal mutation of Xenopus laevis tadpoles.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Droin, A; Beauchemin, M L</p> <p>1975-10-01</p> <p>'Immobile' (<span class="hlt">im</span>) is a recessive lethal mutation discovered in the F3 of a Xenopus (Xenopus laevis laevis) originating from a mesodermal nucleus of a neurula transplanted into an enucleated egg. The <span class="hlt">im</span> embryos do not contract after mechanical stimulation nor do they present any spontaneous contraction from the neurula stage onwards. Development proceeds normally during the first days after which deformation of the lower jaw and tail are observed. The <span class="hlt">im</span> tadpoles die when normal controls are at the feeding stage. Nevous and muscular tissues are histologically normal in the mutant tadpoles; at advanced stages, however, an irregularity in the path of the myofibrils is observed which is especially conspicuous in the electron microscope. Cholinesterases and ATPase are present in the mutant muscles. Parabiosis and chimerae experiments have shown that parabionts and grafts behave according to their own genotype. Cultures of presumptive axial systems with or without ectoderm lead to the conclusion that, first of all, the abnormality is situated in the mesodermal cells and secondly that the first muscular contractions in normal Xenopus laevis are of myogenic origin. The banding pattern of the myofibrils is normal as was shown by obtaining contractions of glycerol extracted in myoblasts with ATP. It seems therefore that in this mutation, the abnormality is situated in the membraneous system of the muscular cell, sarcoplasmic reticulum and/or tubular system as is probably the case in the mdg mutation of the mouse.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/276397','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/276397"><span>Challenges of developing a GC/<span class="hlt">IMS</span> based personal chemical hazard detector</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Arnold, N.S.; Dworzanski, J.P.; Meuzelaar, H.L.C.; McClennen, W.H.</p> <p>1995-12-31</p> <p>Hand-portable gas chromatography/ion mobility spectrometry (GC/<span class="hlt">IMS</span>) techniques have been identified as a promising area of development for field and process related analytical problems. Recent development of extremely small (15 inch) personal <span class="hlt">IMS</span> detection devices offer new prospects for creating a miniaturized GC/<span class="hlt">IMS</span> unit. This paper provides a feasibility examination of personal GC/<span class="hlt">IMS</span> based on the automated vapor sampling-transfer line gas chromatography (AVS-TLGC) approach previously utilized in developing hand-portable GC/<span class="hlt">IMS</span> instrumentation. Special focus is placed upon developing low power strategies for implementing this approach. The means for achieving low power operation for extended personal use has focused on pulsed, on-demand operation of the sampling systems, low (ambient) temperature GC operation, reduced GC flow rates and pressure drops and modification of the internal <span class="hlt">IMS</span> system flows. Development efforts to date have utilized an existing prototype miniature <span class="hlt">IMS</span> device, the GI-MINI from Graseby Ionics coupled with modified Enviroprobe AVS-TLGC equipment developed by FemtoScan. Effect of parameters such as GC column position, temperature and carrier gas flow as well as <span class="hlt">IMS</span> purge flows are examined for their effects upon sensitivity and resolution in breadboard GC/<span class="hlt">IMS</span> test instrument. An evaluation of the remaining engineering hurdles limiting the development of personal GC/<span class="hlt">IMS</span> are also presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25348600','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25348600"><span>Trace concentrations of imazethapyr (<span class="hlt">IM</span>) affect floral organs development and reproduction in Arabidopsis thaliana: <span class="hlt">IM</span>-induced inhibition of key genes regulating anther and pollen biosynthesis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Qian, Haifeng; Li, Yali; Sun, Chongchong; Lavoie, Michel; Xie, Jun; Bai, Xiaocui; Fu, Zhengwei</p> <p>2015-01-01</p> <p>Understanding how herbicides affect plant reproduction and growth is critical to develop herbicide toxicity model and refine herbicide risk assessment. Although our knowledge of herbicides toxicity mechanisms at the physiological and molecular level in plant vegetative phase has increased substantially in the last decades, few studies have addressed the herbicide toxicity problematic on plant reproduction. Here, we determined the long-term (4-8 weeks) effect of a chiral herbicide, imazethapyr (<span class="hlt">IM</span>), which has been increasingly used in plant crops, on floral organ development and reproduction in the model plant Arabidopsis thaliana. More specifically, we followed the effect of two <span class="hlt">IM</span> enantiomers (R- and S-<span class="hlt">IM</span>) on floral organ structure, seed production, pollen viability and the transcription of key genes involved in anther and pollen development. The results showed that <span class="hlt">IM</span> strongly inhibited the transcripts of genes regulating A. thaliana tapetum development (DYT1: DYSFUNCTIONAL TAPETUM 1), tapetal differentiation and function (TDF1: TAPETAL DEVELOPMENT AND FUNCTION1), and pollen wall formation and developments (AMS: ABORTED MICROSPORES, MYB103: MYB DOMAIN PROTEIN 103, MS1: MALE STERILITY 1, MS2: MALE STERILITY 2). Since DYT1 positively regulates 33 genes involved in cell-wall modification (such as, TDF1, AMS, MYB103, MS1, MS2) that can catalyze the breakdown of polysaccharides to facilitate anther dehiscence, the consistent decrease in the transcription of these genes after <span class="hlt">IM</span> exposure should hamper anther opening as observed under scanning electron microscopy. The toxicity of <span class="hlt">IM</span> on anther opening further lead to a decrease in pollen production and pollen viability. Furthermore, long-term <span class="hlt">IM</span> exposure increased the number of apurinic/apyrimidinic sites (AP sites) in the DNA of A. thaliana and also altered the DNA of A. thaliana offspring grown in <span class="hlt">IM</span>-free soils. Toxicity of <span class="hlt">IM</span> on floral organs development and reproduction was generally higher in the presence of the R-<span class="hlt">IM</span></p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.V34A..02P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.V34A..02P"><span>CAMECA <span class="hlt">IMS</span> 1300-HR3: The New Generation Ion Microprobe</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Peres, P.; Choi, S. Y.; Renaud, L.; Saliot, P.; Larson, D. J.</p> <p>2016-12-01</p> <p>The success of secondary ion mass spectrometry (SIMS) in Geo- and Cosmo-chemistry relies on its performance in terms of: 1) very high sensitivity (mandatory for high precision measurements or to achieve low detection limits); 2) a broad mass range of elemental and isotopic species, from low mass (H) to high mass (U and above); 3) in-situ analysis of any solid flat polished surface; and 4) high spatial resolution from tens of microns down to sub-micron scale. The <span class="hlt">IMS</span> 1300-HR3 (High Reproducibility, High spatial Resolution, High mass Resolution) is the latest generation of CAMECA's large geometry magnetic sector SIMS (or ion microprobe), successor to the internationally recognized <span class="hlt">IMS</span> 1280-HR. The 1300-HR3delivers unmatched analytical performance for a wide range of applications (stable isotopes, geochronology, trace elements, nuclear safeguards and environmental studies…) due to: • High brightness RF-plasma oxygen ion source with enhanced beam density and current stability, dramatically improving spatial resolution, data reproducibility, and throughput • Automated sample loading system with motorized sample height (Z) adjustment, significantly increasing analysis precision, ease-of-use, and productivity • UV-light microscope for enhanced optical image resolution, together with dedicated software for easy sample navigation (developed by University of Wisconsin, USA) • Low noise 1012Ω resistor Faraday cup preamplifier boards for measuring low signal intensities In addition, improvements in electronics and software have been integrated into the new instrument. In order to meet a growing demand from geochronologists, CAMECA also introduces the KLEORA, which is a fully optimized ion microprobe for advanced mineral dating derived from the <span class="hlt">IMS</span> 1300-HR3. Instrumental developments as well as data obtained for stable isotope and U-Pb dating applications will be presented in detail.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010AGUFMSM11C1781S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010AGUFMSM11C1781S"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa and Ganymede</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sittler, E. C.; Cooper, J. F.; Hartle, R. E.; Paterson, W. R.; Lipatov, A. S.; Paschalidis, N. P.; Coplan, M. A.; Cassidy, T. A.</p> <p>2010-12-01</p> <p>NASA and ESA are planning the joint Europa Jupiter System Mission (EJSM) to the Jupiter system with specific emphases on Europa and Ganymede from these respective space agencies. The Japanese Space Agency is also planning an orbiter mission to explore Jupiter’s magnetosphere and the Galilean satellites. For NASA’s Jupiter Europa Orbiter (JEO) we are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) with two main goals which can also be applied to the other Galilean moons, 1) measure the plasma interaction between Europa and Jupiter’s magnetosphere and 2) infer the 4π surface composition to trace elemental and significant isotopic levels. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa’s sub-surface ocean, while the second gives information about transfer of material between the Galilean moons, and between the moon surfaces and subsurface layers putatively including oceans. The measurement of the interactions for all the Galilean moons can be used to trace the in situ ion measurements of pickup ions back to either Europa’s or Ganymede’s surface from the respectively orbiting spacecraft. The <span class="hlt">IMS</span> instrument, being developed under NASA’s Astrobiology Instrument Development Program (ASTID), would maximally achieve plasma measurement requirements for JEO and EJSM while moving forward our knowledge of Jupiter system composition and source processes to far higher levels than previously envisaged. The ASTID-supported <span class="hlt">IMS</span>, applicable to the NASA spacecraft, is designed to operate in a high radiation environment with minor and trace ion detection capability. The latter goal is achieved by measuring pickup ions at spacecraft altitudes and using a 3D hybrid model of the interaction in order to construct 3D global model of the electric and magnetic fields around these bodies. The pickup ion trajectories can then be traced back down to the surface. In the case of Europa we also show that Europa’s ionosphere is</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PhuZ...37...86T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PhuZ...37...86T"><span>Was leistet ein Sportler? Kraft, Leistung und Energie <span class="hlt">im</span> Muskel</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Thaller, Sigrid; Mathelitsch, Leopold</p> <p>2006-01-01</p> <p>Der Leistungsbegriff ist <span class="hlt">im</span> Sport weiter gefasst als in der Physik. In beiden Fällen liegt der Fokus jedoch auf einer pro Zeiteinheit erfolgten Energieumsetzung. Allerdings gibt die rein physikalische Leistung nicht immer Auskunft über den Energieumsatz der Muskeln. Die Muskelkraft hängt von der Kontraktionsgeschwindigkeit des Muskels ab. Ein Muskel verhält sich also anders als eine Feder. Für den Hochleistungssport müssen die Energieumsätze der Muskeln durch spezielle Trainings- und Nahrungsprogramme optimiert werden.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014JPhCS.491a1001K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014JPhCS.491a1001K"><span>PREFACE: 3rd International Meeting on Silicene (<span class="hlt">IMS</span>-3)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kara, Abdelkader; Enriquez, Hanna; Lemaire, Jean Louis; Oughaddou, Hamid</p> <p>2014-03-01</p> <p>Silicene, the new supernova material Silicon is formed in a large amount during supernova nucleo-synthesis and it is the 8th most common chemical element in the universe. Today modern electronics make large use of bulk silicon, which has consequently an extremely large impact on the world industry and economy. The need for more powerful, faster and less energy-consuming integrated circuits requires in the future the use of nanotechnologies. The ultimate step concerning silicon is silicene (the 2D silicon-based analogue of graphene). This material is of paramount importance as it requires the use of the same technologies and production lines as silicon. Even if theoreticians had predicted its possible existence, it is only in 2010 that a team of pioneers from CINAM-France, ISMO-France and UCF-USA has presented for the first time the experimental evidence of the formation of silicene. Since then research is exploding (like a supernova!) both on the experimental and theoretical sides, with the main aim of replacing bulk silicon with this potentially revolutionary material. However, before any possible industrial use, it has first to be prepared or synthesized in various stripe and sheet shapes on insulating surfaces on which its physical and chemical properties have to be analyzed in detail. A second step is its chemical functionalization through various dopants to achieve different tasks, expected or not yet imagined. Chemists and physicists, experimentalists and theoreticians are involved in this thrilling work. A wide array of techniques, from the subtle chemistry reaction networks, to all those of experimental surface science (from synchrotron radiation to scanning tunneling microscopy) as well as those of theoretical chemistry (from {\\it ab initio} to density functional theory calculations) are involved. Big progress has been made since 2010 and the success of this third International Meeting on Silicene (<span class="hlt">IMS</span>-3) is demonstrated by the present proceedings</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3365540','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3365540"><span>Microwave Assisted Synthesis of Py-<span class="hlt">Im</span> Polyamides</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2012-01-01</p> <p>Microwave synthesis was utilized to rapidly build Py-<span class="hlt">Im</span> polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and Glucocorticoid Response Elements was synthesized in 56% yield after 20 linear steps and HPLC purification. It was confirmed by Mosher amide derivatization of the polyamide that a chiral α-amino acid does not racemize after several additional coupling steps. PMID:22578091</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=learning+AND+ger&pg=2&id=EJ847882','ERIC'); return false;" href="http://eric.ed.gov/?q=learning+AND+ger&pg=2&id=EJ847882"><span>Building Adaptive Game-Based Learning Resources: The Integration of <span class="hlt">IMS</span> Learning Design and</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Burgos, Daniel; Moreno-Ger, Pablo; Sierra, Jose Luis; Fernandez-Manjon, Baltasar; Specht, Marcus; Koper, Rob</p> <p>2008-01-01</p> <p><span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span>-LD) is a specification to create units of learning (UoLs), which express a certain pedagogical model or strategy (e.g., adaptive learning with games). However, the authoring process of a UoL remains difficult because of the lack of high-level authoring tools for <span class="hlt">IMS</span>-LD, even more so when the focus is on specific topics,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=Munoz+Moreno%2c+Jose+Luis&id=EJ847882','ERIC'); return false;" href="https://eric.ed.gov/?q=Munoz+Moreno%2c+Jose+Luis&id=EJ847882"><span>Building Adaptive Game-Based Learning Resources: The Integration of <span class="hlt">IMS</span> Learning Design and</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Burgos, Daniel; Moreno-Ger, Pablo; Sierra, Jose Luis; Fernandez-Manjon, Baltasar; Specht, Marcus; Koper, Rob</p> <p>2008-01-01</p> <p><span class="hlt">IMS</span> Learning Design (<span class="hlt">IMS</span>-LD) is a specification to create units of learning (UoLs), which express a certain pedagogical model or strategy (e.g., adaptive learning with games). However, the authoring process of a UoL remains difficult because of the lack of high-level authoring tools for <span class="hlt">IMS</span>-LD, even more so when the focus is on specific topics,…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_6 --> <div id="page_7" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="121"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20170005767','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20170005767"><span>Flight Crew Survey Responses from the Interval Management (<span class="hlt">IM</span>) Avionics Phase 2 Flight Test</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Baxley, Brian T.; Swieringa, Kurt A.; Wilson, Sara R.; Roper, Roy D.; Hubbs, Clay E.; Goess, Paul A.; Shay, Richard F.</p> <p>2017-01-01</p> <p>The Interval Management (<span class="hlt">IM</span>) Avionics Phase 2 flight test used three aircraft over a nineteen day period to operationally evaluate a prototype <span class="hlt">IM</span> avionics. Quantitative data were collected on aircraft state data and <span class="hlt">IM</span> spacing algorithm performance, and qualitative data were collected through end-of-scenario and end-of-day flight crew surveys. The majority of the <span class="hlt">IM</span> operations met the performance goals established for spacing accuracy at the Achieve-by Point and the Planned Termination Point, however there were operations that did not meet goals for a variety of reasons. While the positive spacing accuracy results demonstrate the prototype <span class="hlt">IM</span> avionics can contribute to the overall air traffic goal, critical issues were also identified that need to be addressed to enhance <span class="hlt">IM</span> performance. The first category was those issues that impacted the conduct and results of the flight test, but are not part of the <span class="hlt">IM</span> concept or procedures. These included the design of arrival and approach procedures was not ideal to support speed as the primary control mechanism, the ground-side of the Air Traffic Management Technology Demonstration (ATD-1) integrated concept of operations was not part of the flight test, and the high workload to manually enter the information required to conduct an <span class="hlt">IM</span> operation. The second category was issues associated with the <span class="hlt">IM</span> spacing algorithm or flight crew procedures. These issues include the high frequency of <span class="hlt">IM</span> speed changes and reversals (accelerations), a mismatch between the deceleration rate used by the spacing algorithm and the actual aircraft performance, and some spacing error calculations were sensitive to normal operational variations in aircraft airspeed or altitude which triggered additional <span class="hlt">IM</span> speed changes. Once the issues in these two categories are addressed, the future <span class="hlt">IM</span> avionics should have considerable promise supporting the goals of improving system throughput and aircraft efficiency.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17106771','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17106771"><span><span class="hlt">IMS</span> method performance analyses for Giardia in water under differing conditions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hsu, Bing-Mu; Huang, Chihpin</p> <p>2007-08-01</p> <p>Immunomagnetic separation (<span class="hlt">IMS</span>) has been specified as a standard method for the measurement of Giardia under USEPA Method 1623. In this study, <span class="hlt">IMS</span> was evaluated on the basis of recovery efficiencies for Giardia cysts under various <span class="hlt">IMS</span> operation conditions. Significant change in recovery was observed by altering the debris ratio of water samples. Notably, cyst recovery efficiencies utilizing <span class="hlt">IMS</span> dropped with increased turbidity, and results for varying dosages of magnetic beads and cysts indicate that 1 / 100 immunomagnetic beads is sufficient to conjugate large numbers of cysts. Changing vessel volume and replacing the sample buffer had no significant effect on cyst recovery efficiencies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4140651','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4140651"><span>Complexation of Amino Compounds by 18C6 Improves Selectivity by <span class="hlt">IMS-IMS</span>-MS: Application to Petroleum Characterization</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Li, Zhiyu; Valentine, Stephen J.; Clemmer, David E.</p> <p>2013-01-01</p> <p>Complexation of a series of related amino compounds by 18-crown-6 ether (18C6) is studied as a means of improving the resolution of mixtures by combinations of ion mobility spectrometry (<span class="hlt">IMS</span>) and mass spectrometry (MS) techniques. Mixtures of the isomeric amines n-octylamine (NOA), dibutylamine (DBA), and diisopropylethylamine (DIPEA) were electrosprayed to produce gaseous [M + H]+ ions. These species have overlapping mobilities and are not resolved by <span class="hlt">IMS</span>. Addition of 18C6 yields [M + 18C6 + H]+ ion complexes that are resolved by <span class="hlt">IMS</span>. In subsequent experiments, [M + 18C6 + H]+ ion complexes are separated according to their mobilities and specific species are selected and exposed to collisional activation. This analysis yields dissociation voltages that are inversely correlated with the number of separate substitutions on the nitrogen atom of the amino compounds; dissociation voltages of ~40, ~90, and ~150 V are obtained for the tri-, di-, and mono-substituted amino compounds DIPEA, DBA, and NOA, respectively. For these complexes, an inverse correlation is also observed with respect to the gas-phase basicities (GB) of the amino compounds (964, 935, and 895 kJ mol−1, respectively). Studies of 18C6 complexes with a series of n-alkylamines (CnH2n+3N where n=3 to 18, respectively) show that dissociation voltages increase systematically (from ~140 to ~190 V) under the conditions employed. The sensitivity to collision energy provides an additional means of distinguishing between classes of compounds. The approach is extended as a means of separating nitrogen-containing compounds from petroleum. PMID:21472516</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100033350','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100033350"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa and Ganymede</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Sittler, E.; Cooper, J.; Hartle, R.; Lipatov, A.; Mahaffy, P.; Paterson, W.; Paschalidis, N.; Coplan, M.; Cassidy, T.</p> <p>2010-01-01</p> <p>NASA and ESA are planning the joint Europa Jupiter System Mission (EJSM) to the Jupiter system with specific emphasis to Europa and Ganymede, respectively. The Japanese Space Agency is also planning an orbiter mission to explore Jupiter's magnetosphere and the Galilean satellites. For NASA's Jupiter Europa Orbiter (JEO) we are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) with two main goals which can also be applied to the other Galilean moons, 1) measure the plasma interaction between Europa and Jupiter's magnetosphere and 2) infer the 4n surface composition to trace elemental [1] and significant isotopic levels. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa's sub-surface ocean, while the second gives information about transfer of material between the Galilean moons, and between the moon surfaces and subsurface layers putatively including oceans. The measurement of the interactions for all the Galilean moons can be used to trace the in situ ion measurements of pickup ions back to either Europa's or Ganymede's surface from the respectively orbiting spacecraft. The <span class="hlt">IMS</span> instrument, being developed under NASA's Astrobiology Instrument Development Program, would maximally achieve plasma measurement requirements for JEO and EJSM while moving forward our knowledge of Jupiter system composition and source processes to far higher levels than previously envisaged.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26934004','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26934004"><span>Utility of the <span class="hlt">Im</span>PACT test with deaf adolescents.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Reesman, Jennifer; Pineda, Jill; Carver, Jenny; Brice, Patrick J; Zabel, T Andrew; Schatz, Philip</p> <p>2016-02-01</p> <p>The goals of the study included empirical examination of the utility of the Immediate and Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) test with adolescents who are deaf or hard-of-hearing and to investigate patterns of performance at baseline that may arise in the assessment of this population. Baseline assessment of student-athletes has been conducted on a widespread scale with focus on performance of typically developing student-athletes and some clinical groups, though to date no studies have examined adolescents who are deaf or hard-of-hearing. Retrospective and de-identified <span class="hlt">Im</span>PACT baseline test used with deaf and hard-of-hearing high-school student-athletes (N = 143; 66% male, mean age = 16.11) was examined. Review indicated significant differences in some composite scores between the deaf and hard-of-hearing group and hearing normative comparisons. A possible marker of task misunderstanding was identified to occur more frequently within the deaf and hard-of-hearing sample (13% in deaf sample vs. .31% in hearing sample). Results may provide support for the consideration and use of additional measures to ensure comprehension of task demands when considering this tool for use with deaf and hard-of-hearing adolescents.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFM.S52B..08M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFM.S52B..08M"><span>Completing and sustaining <span class="hlt">IMS</span> network for the CTBT Verification Regime</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Meral Ozel, N.</p> <p>2015-12-01</p> <p>The CTBT International Monitoring System is to be comprised of 337 facilities located all over the world for the purpose of detecting and locating nuclear test explosions. Major challenges remain, namely the completion of the network where most of the remaining stations have either environmental, logistical and/or political issues to surmont (89% of the stations have already been built) and the sustainment of a reliable and state-of the-art network covering 4 technologies - seismic, infrasound , hydroacoustic and radionuclide. To have a credible and trustworthy verification system ready for entry into force of the Treaty, the CTBTO is protecting and enhancing its investment of its global network of stations and is providing effective data to the International Data Centre (IDC) and Member States. Regarding the protection of the CTBTO's investment and enhanced sustainment of <span class="hlt">IMS</span> station operations, the <span class="hlt">IMS</span> Division is enhancing the capabilities of the monitoring system by applying advances in instrumentation and introducing new software applications that are fit for purpose. Some examples are the development of noble gas laboratory systems to process and analyse subsoil samples, development of a mobile noble gas system for onsite inspection purposes, optimization of Beta Gamma detectors for Xenon detection, assessing and improving the efficiency of wind noise reduction systems for infrasound stations, development and testing of infrasound stations with a self-calibrating capability, and research into the use of modular designs for the hydroacoustic network.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19990017744&hterms=Theology&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DTheology','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19990017744&hterms=Theology&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3DTheology"><span><span class="hlt">IM</span>7/LARC(tm) MPEI-1 Polymide Composites</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Hou, T. H.; Cano, R. J.; Jensen, B. J.</p> <p>1998-01-01</p> <p>LARC(Trademark) MPEI-1 (Langley Research Center(Trademark) modified phenylethynyl imide-1) phenylethynyl containing aromatic polymide, is based on the reaction of biphenyl dianhydride (BPDA), 3,4'-oxydianiline (3,4'-ODA), 1,3-bis(3-aminophenoxy)benzene (APB), 2,4,6-triaminopyrimidine (TAP) and 4-phenylethynyl phthalic anhydride (PEPA), presumably resulting in a mixture of linear, branched and star shaped phenylethynyl containing imides which was evaluated as a matrix for high-performance composites. The poly(amid acid) solution of MPEI-1 in N-methypyrrolidinone was synthesized at 35% and 42% solids. Unidirectional prepreg was fabricated from these solutions and Hercules <span class="hlt">IM</span>7 carbon fiber utilizing NASA- Langley's multipurpose prepreg machine. The temperature-dependent volatile depletion rates, thermal crystallization behavior and resin theology were characterized. Based on this information, a composite molding cycle was developed which yielded well consolidated, void-free laminates. Composite mechanical properties such as short beam shear strength, longitudinal and transverse flexural strength and flexural modulus, longitudinal tensile strength and notched and unnotched compression strengths were measured at room temperature (RT) and elevated temperatures. These mechanical properties are compared with those of <span class="hlt">IM</span>7/LARC(Trademark) PETI-5 composites.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PApGe.171..377G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PApGe.171..377G"><span>The Applicability of Incoherent Array Processing to <span class="hlt">IMS</span> Seismic Arrays</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gibbons, Steven J.</p> <p>2014-03-01</p> <p>The seismic arrays of the International Monitoring System (<span class="hlt">IMS</span>) for the Comprehensive Nuclear-Test-Ban Treaty (CTBT) are highly diverse in size and configuration, with apertures ranging from under 1 km to over 60 km. Large and medium aperture arrays with large inter-site spacings complicate the detection and estimation of high-frequency phases lacking coherence between sensors. Pipeline detection algorithms often miss such phases, since they only consider frequencies low enough to allow coherent array processing, and phases that are detected are often attributed qualitatively incorrect backazimuth and slowness estimates. This can result in missed events, due to either a lack of contributing phases or by corruption of event hypotheses by spurious detections. It has been demonstrated previously that continuous spectral estimation can both detect and estimate phases on the largest aperture arrays, with arrivals identified as local maxima on beams of transformed spectrograms. The estimation procedure in effect measures group velocity rather than phase velocity, as is the case for classical f-k analysis, and the ability to estimate slowness vectors requires sufficiently large inter-sensor distances to resolve time-delays between pulses with a period of the order 4-5 s. Spectrogram beampacking works well on five <span class="hlt">IMS</span> arrays with apertures over 20 km (NOA, AKASG, YKA, WRA, and KURK) without additional post-processing. Seven arrays with 10-20 km aperture (MJAR, ESDC, ILAR, KSRS, CMAR, ASAR, and EKA) can provide robust parameter estimates subject to a smoothing of the resulting slowness grids, most effectively achieved by convolving the measured slowness grids with the array response function for a 4 or 5 s period signal. Even for medium aperture arrays which can provide high-quality coherent slowness estimates, a complementary spectrogram beampacking procedure could act as a quality control by providing non-aliased estimates when the coherent slowness grids display</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28176592','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28176592"><span><span class="hlt">I'm</span> just a girl who can't say no... or yes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bates, Jane</p> <p>2017-02-08</p> <p>'<span class="hlt">I'm</span> just a girl who can't say no,' sang Ado Annie in the musical Oklahoma. Well, <span class="hlt">I'm</span> just a girl who can't say yes or no, I discovered, when taking part in a health questionnaire. 'These are yes or no answers,' said the person grilling me, pointedly.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2013-title40-vol2/pdf/CFR-2013-title40-vol2-sec51-352.pdf','CFR2013'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2013-title40-vol2/pdf/CFR-2013-title40-vol2-sec51-352.pdf"><span>40 CFR 51.352 - Basic <span class="hlt">I/M</span> performance standard.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2013&page.go=Go">Code of Federal Regulations, 2013 CFR</a></p> <p></p> <p>2013-07-01</p> <p>... areas with existing <span class="hlt">I/M</span> programs, 1983. For areas newly subject, 1994. (3) Test frequency. Annual... implemented <span class="hlt">I/M</span> programs shall include NOX controls from the start. (c) On-board diagnostics (OBD). For those... of malfunctions or system deterioration identified by or affecting OBD systems as specified in §...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=ieee+AND+power&pg=2&id=EJ936367','ERIC'); return false;" href="http://eric.ed.gov/?q=ieee+AND+power&pg=2&id=EJ936367"><span>Computer-Aided Teaching Using MATLAB/Simulink for Enhancing an <span class="hlt">IM</span> Course With Laboratory Tests</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bentounsi, A.; Djeghloud, H.; Benalla, H.; Birem, T.; Amiar, H.</p> <p>2011-01-01</p> <p>This paper describes an automatic procedure using MATLAB software to plot the circle diagram for two induction motors (<span class="hlt">IMs</span>), with wound and squirrel-cage rotors, from no-load and blocked-rotor tests. The advantage of this approach is that it avoids the need for a direct load test in predetermining the <span class="hlt">IM</span> characteristics under reduced power.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol2/pdf/CFR-2012-title40-vol2-sec51-352.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol2/pdf/CFR-2012-title40-vol2-sec51-352.pdf"><span>40 CFR 51.352 - Basic <span class="hlt">I/M</span> performance standard.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-07-01</p> <p>... following model <span class="hlt">I/M</span> program inputs and local characteristics, such as vehicle mix and local fuel controls... both in operation and for SIP approval. (1) Network type. Centralized testing. (2) Start date. For areas with existing <span class="hlt">I/M</span> programs, 1983. For areas newly subject, 1994. (3) Test frequency....</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=ieee+AND+paper&pg=6&id=EJ993154','ERIC'); return false;" href="http://eric.ed.gov/?q=ieee+AND+paper&pg=6&id=EJ993154"><span>The Conceptual Structure of <span class="hlt">IMS</span> Learning Design Does Not Impede Its Use for Authoring</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Derntl, M.; Neumann, S.; Griffiths, D.; Oberhuemer, P.</p> <p>2012-01-01</p> <p><span class="hlt">IMS</span> Learning Design (LD) is the only available interoperability specification in the area of technology enhanced learning that allows the definition and orchestration of complex activity flows and resource environments in a multirole setting. <span class="hlt">IMS</span> LD has been available since 2003, and yet it has not been widely adopted either by practitioners or by…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/959942','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/959942"><span>Crystal Structure of the 25 kDa Subunit of Human Cleavage Factor <span class="hlt">I{m</span>}</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Coseno,M.; Martin, G.; Berger, C.; Gilmartin, G.; Keller, W.; Doublie, S.</p> <p>2008-01-01</p> <p>Cleavage factor <span class="hlt">Im</span> is an essential component of the pre-messenger RNA 3'-end processing machinery in higher eukaryotes, participating in both the polyadenylation and cleavage steps. Cleavage factor <span class="hlt">Im</span> is an oligomer composed of a small 25 kDa subunit (CF <span class="hlt">Im</span>25) and a variable larger subunit of either 59, 68 or 72 kDa. The small subunit also interacts with RNA, poly(A) polymerase, and the nuclear poly(A)-binding protein. These protein-protein interactions are thought to be facilitated by the Nudix domain of CF <span class="hlt">Im</span>25, a hydrolase motif with a characteristic {alpha}/{beta}/{alpha} fold and a conserved catalytic sequence or Nudix box. We present here the crystal structures of human CF <span class="hlt">Im</span>25 in its free and diadenosine tetraphosphate (Ap4A) bound forms at 1.85 and 1.80 Angstroms, respectively. CF <span class="hlt">Im</span>25 crystallizes as a dimer and presents the classical Nudix fold. Results from crystallographic and biochemical experiments suggest that CF <span class="hlt">Im</span>25 makes use of its Nudix fold to bind but not hydrolyze ATP and Ap4A. The complex and apo protein structures provide insight into the active oligomeric state of CF <span class="hlt">Im</span> and suggest a possible role of nucleotide binding in either the polyadenylation and/or cleavage steps of pre-messenger RNA 3'-end processing.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=software+AND+definition&pg=3&id=EJ993154','ERIC'); return false;" href="https://eric.ed.gov/?q=software+AND+definition&pg=3&id=EJ993154"><span>The Conceptual Structure of <span class="hlt">IMS</span> Learning Design Does Not Impede Its Use for Authoring</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Derntl, M.; Neumann, S.; Griffiths, D.; Oberhuemer, P.</p> <p>2012-01-01</p> <p><span class="hlt">IMS</span> Learning Design (LD) is the only available interoperability specification in the area of technology enhanced learning that allows the definition and orchestration of complex activity flows and resource environments in a multirole setting. <span class="hlt">IMS</span> LD has been available since 2003, and yet it has not been widely adopted either by practitioners or by…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=Matlab&pg=4&id=EJ936367','ERIC'); return false;" href="https://eric.ed.gov/?q=Matlab&pg=4&id=EJ936367"><span>Computer-Aided Teaching Using MATLAB/Simulink for Enhancing an <span class="hlt">IM</span> Course With Laboratory Tests</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bentounsi, A.; Djeghloud, H.; Benalla, H.; Birem, T.; Amiar, H.</p> <p>2011-01-01</p> <p>This paper describes an automatic procedure using MATLAB software to plot the circle diagram for two induction motors (<span class="hlt">IMs</span>), with wound and squirrel-cage rotors, from no-load and blocked-rotor tests. The advantage of this approach is that it avoids the need for a direct load test in predetermining the <span class="hlt">IM</span> characteristics under reduced power.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=High+AND+Impact+AND+Presentations+AND+Skills&pg=3&id=EJ620177','ERIC'); return false;" href="http://eric.ed.gov/?q=High+AND+Impact+AND+Presentations+AND+Skills&pg=3&id=EJ620177"><span>Having an <span class="hlt">IM</span>-PACT: A Model for Improving Instructional Presentations.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Small, Ruth</p> <p>2000-01-01</p> <p>Explains <span class="hlt">IM</span>-PACT (Instructional Model-Purpose, Audience, Content, Technique), a framework for systematic lesson design in an information literacy context. Includes an example of <span class="hlt">IM</span>-PACT's application to a high school-level information skills lesson plan, collaboratively designed by the teacher-librarian and English teacher. (LRW)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..12.8364B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..12.8364B"><span>Use of the <span class="hlt">IMS</span> infrasound network for global atmospheric studies</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Blanc, Elisabeth; Le Pichon, Alexis; Ceranna, Lars; Farges, Thomas</p> <p>2010-05-01</p> <p>The development of the Infrasound International Monitoring System (<span class="hlt">IMS</span>), used for the verification of the Comprehensive Test Ban Treaty, represents a powerful tool to measure permanently, at a global scale and over large periods of time, the disturbances of the atmosphere. The network is mostly sensitive to infrasound in the range 0.02 to 5 Hz, but it also measures gravity waves at lower frequencies and tidal waves. Measurements with the <span class="hlt">IMS</span> infrasound network provide both the state of the atmospheric wave guide and of the atmospheric waves which can be used to study the dynamics of the atmosphere. The first way is to study the variability of infrasound from quasi continuous sources such as ocean swells or volcanoes in relation with changes in large scale atmospheric structures. Since infrasound propagate in the stratosphere and mesosphere, atmospheric parameters which affect the infrasound propagation can be investigated from ground measurements of infrasound. Azimuth changes of infrasound from volcanis eruption were used to retrieve mesospheric zonal winds. The amplitude fluctuations of infrasound from ocean swells represent planetary waves which modulate the atmospheric wave guide. Fluctuations are much larger in Northern hemispheres than in Southern hemisphere, because the amplitude of planetary waves is larger in Northern hemisphere where continental areas are more important. Infrasound monitoring also revealed anomalies at a seasonal scale in Antarctica or at the scale of several days in Arctic regionsin relation with Sudden Stratospheric Warming. The second way is the direct observation of large scale gravity waves. These waves, mainly produced in the troposphere, propagate upwards and break in the stratosphere producing a chaotic forcing of the stratosphere. This is at the origin of a slow and large scale motion in which air masses are driven upward and poleward from the tropical lower stratosphere. In polar regions, they are pushed downward producing</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010prod.book..117N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010prod.book..117N"><span>Berechnung verkehrlicher Substitutionseffekte <span class="hlt">im</span> Personenverkehr bei Online-Shopping</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Nerlich, Mark R.; Schiffner, Felix; Vogt, Walter; Rauh, Jürgen; Breidenbach, Petra</p> <p></p> <p>Für Güter des täglichen, mittelfristigen und langfristigen Bedarfs sowie für das Beispiel Baumarktartikel wird das Potenzial für Personenverkehrsaufwand von Einkaufsaktivtäten quantitativ abgeschätzt. Die entwickelten Algorithmen behandeln die einkaufsvorbereitende Information und den eigentlichen Einkauf, d.h. den Erwerb eines Gutes, separat. Informationsaktivitäten haben insbesondere bei höherwertigen Gütern einen hohen Stellenwert und damit auch verkehrliche Relevanz. Wie Berechnungen zeigen, spart Online-Shopping Informations- und Einkaufsverkehrsaufwand <span class="hlt">im</span> Pkw-Verkehr ein. Die notwendigen Eingangsdaten wie differenzierte Informations- und Einkaufshäufigkeiten sowie verkehrliche Parameter zu Verkehrsmittelwahl, Entfernungen und Wegekopplungen wurden aus eigenen Erhebungen gewonnen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1022198','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1022198"><span>Software enhancements to the IVSEM model of the CTBTO <span class="hlt">IMS</span>.</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Damico, Joseph P.</p> <p>2011-03-01</p> <p>Sandia National Laboratories (SNL) developed the Integrated Verification System Evaluation Model (IVSEM) to estimate the performance of the International Monitoring System (<span class="hlt">IMS</span>) operated by the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). IVSEM was developed in several phases between 1995 and 2000. The model was developed in FORTRAN with an IDL-based user interface and was compiled for Windows and UNIX operating systems. Continuing interest in this analysis capability, coupled with numerous advances in desktop computer hardware and software since IVSEM was written, enabled significant improvements to IVSEM run-time performance and data analysis capabilities. These improvements were implemented externally without modifying the FORTRAN executables, which had been previously verified. This paper describes the parallelization approach developed to significantly reduce IVSEM run-times and the new test setup and analysis tools developed to facilitate better IVSEM operation.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_7 --> <div id="page_8" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="141"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JHEP...08..071I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JHEP...08..071I"><span>ODE/<span class="hlt">IM</span> correspondence and the Argyres-Douglas theory</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ito, Katsushi; Shu, Hongfei</p> <p>2017-08-01</p> <p>We study the quantum spectral curve of the Argyres-Douglas theories in the Nekrasov-Sahashvili limit of the Omega-background. Using the ODE/<span class="hlt">IM</span> correspondence we investigate the quantum integrable model corresponding to the quantum spectral curve. We show that the models for the A 2 N -type theories are non-unitary coset models ( A 1)1 × ( A 1) L /( A 1) L+1 at the fractional level L=2/2N+1-2 , which appear in the study of the 4d/2d correspondence of N = 2 superconformal field theories. Based on the WKB analysis, we clarify the relation between the Y-functions and the quantum periods and study the exact Bohr-Sommerfeld quantization condition for the quantum periods. We also discuss the quantum spectral curves for the D and E type theories.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23104048','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23104048"><span>Sorrell v. <span class="hlt">IMS</span> Health: issues and opportunities for informaticians.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Petersen, Carolyn; Demuro, Paul; Goodman, Kenneth W; Kaplan, Bonnie</p> <p>2013-01-01</p> <p>In 2011, the US Supreme Court decided Sorrell v. <span class="hlt">IMS</span> Health, Inc., a case that addressed the mining of large aggregated databases and the sale of prescriber data for marketing prescription drugs. The court struck down a Vermont law that required data mining companies to obtain permission from individual providers before selling prescription records that included identifiable physician prescription information to pharmaceutical companies for drug marketing. The decision was based on constitutional free speech protections rather than data sharing considerations. Sorrell illustrates challenges at the intersection of biomedical informatics, public health, constitutional liberties, and ethics. As states, courts, regulatory agencies, and federal bodies respond to Sorrell, informaticians' expertise can contribute to more informed, ethical, and appropriate policies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3555336','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3555336"><span>Sorrell v. <span class="hlt">IMS</span> Health: issues and opportunities for informaticians</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Petersen, Carolyn; DeMuro, Paul; Goodman, Kenneth W; Kaplan, Bonnie</p> <p>2013-01-01</p> <p>In 2011, the US Supreme Court decided Sorrell v. <span class="hlt">IMS</span> Health, Inc., a case that addressed the mining of large aggregated databases and the sale of prescriber data for marketing prescription drugs. The court struck down a Vermont law that required data mining companies to obtain permission from individual providers before selling prescription records that included identifiable physician prescription information to pharmaceutical companies for drug marketing. The decision was based on constitutional free speech protections rather than data sharing considerations. Sorrell illustrates challenges at the intersection of biomedical informatics, public health, constitutional liberties, and ethics. As states, courts, regulatory agencies, and federal bodies respond to Sorrell, informaticians’ expertise can contribute to more informed, ethical, and appropriate policies. PMID:23104048</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22342151','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22342151"><span>Absolute properties of the eclipsing binary star <span class="hlt">IM</span> Persei</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Lacy, Claud H. Sandberg; Torres, Guillermo; Fekel, Francis C.; Muterspaugh, Matthew W.; Southworth, John E-mail: gtorres@cfa.harvard.edu E-mail: matthew1@coe.tsuniv.edu</p> <p>2015-01-01</p> <p><span class="hlt">IM</span> Per is a detached A7 eccentric eclipsing binary star. We have obtained extensive measurements of the light curve (28,225 differential magnitude observations) and radial velocity curve (81 spectroscopic observations) which allow us to fit orbits and determine the absolute properties of the components very accurately: masses of 1.7831 ± 0.0094 and 1.7741 ± 0.0097 solar masses, and radii of 2.409 ± 0.018 and 2.366 ± 0.017 solar radii. The orbital period is 2.25422694(15) days and the eccentricity is 0.0473(26). A faint third component was detected in the analysis of the light curves, and also directly observed in the spectra. The observed rate of apsidal motion is consistent with theory (U = 151.4 ± 8.4 year). We determine a distance to the system of 566 ± 46 pc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..14.9062L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..14.9062L"><span>Observed and predicted performance of the global <span class="hlt">IMS</span> infrasound network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Le Pichon, A.; Ceranna, L.; Landes, M.</p> <p>2012-04-01</p> <p>The International Monitoring System (<span class="hlt">IMS</span>) infrasound network is being deployed to monitor compliance with the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Global-scale analyses of data recorded by this network indicate that the detection capability exhibits strong spatio-temporal variations. Previous studies estimated radiated acoustic source energy from remote infrasound observations using empirical yield-scaling relations, which account for the along-path stratospheric winds. Although the empirical wind correction reduces the variance in the explosive energy versus pressure relationship, large error remains in the yield estimates. Numerical modeling techniques are now widely employed to investigate the role of different factors describing atmospheric infrasound sources and propagation. Here we develop a theoretical attenuation relation from a large set of numerical simulations using the Parabolic Equation method. This relation accounts for the effects of the source frequency; geometrical spreading and dissipation; and realistic atmospheric specifications on the pressure wave attenuation. Compared with previous studies, the derived attenuation relation incorporates a more realistic physical description of infrasound propagation. By incorporating real ambient noise information at the receivers, we obtain the minimum detectable source amplitude in the frequency band of interest for detecting explosions. Empirical relations between the source spectrum and explosion yield are used to infer detection thresholds in tons of TNT equivalent. In the context of future verification of the CTBT, the obtained attenuation relation provides a more realistic picture of the spatio-temporal variability of the <span class="hlt">IMS</span> network performance. The attenuation relation could also be used in the design and maintenance of an arbitrary infrasound monitoring network.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2001PhuZ...32..106S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2001PhuZ...32..106S"><span>Das Isotopenthermometer <span class="hlt">im</span> ewigen Eis: Mechanismen globaler Klimaschwankungen</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Stauffer, Bernhard</p> <p></p> <p>Die Analysen von zwei Bohrkernen <span class="hlt">im</span> grönländischen Eis haben unser Wissen über Klimaschwankungen und deren mögliche Ursachen stark erweitert. Die 18 O-Messreihe zeigt, dass der Übergang von der letzten Eiszeit zur Nacheiszeit in drastischen Sprüngen erfolgte und dass es auch während der Eiszeit schnelle, drastische Klimaänderungen, so genannte Dansgaard-Oeschger -Ereignisse gab. Basierend auf der heute gültigen Beziehung zwischen mittlerer Jahrestemperatur und 18 O-Wert nahm man an, dass der Temperaturanstieg zwischen Eiszeitmaximum und Nacheiszeit rund 12°C und zu Beginn eines Dansgaard-Oeschge-Ereignisses rund 8°C betrugen. Neue Kalibrationsmethoden haben gezeigt, dass die Temperatursprünge praktisch doppelt so groß waren, wie die mit der Dansgaard-Beziehung ermittelten. Erstaunlich sind vor allem die schnellen Temperaturanstiege. Ein Temperaturanstieg von mehr als 10°C e folgte oft in wenigen Jahrzehnten. Die Methanmessreihe ergab, dass die Dansgaard-Oeschger -Ereignisse kein auf Grönland beschränktes Phänomen sind. Es sind Klimaschwankungen von globaler Bedeutung. Die zeitliche Synchronisation von Messreihen auf Grönland und der Antarktis mithilfe von Methanvariationen ergab, dass einer abrupten Erwärmung in Grönland oft eine Erwärmung in der Antarktis vorausging. Von zwei Kernbohrungen <span class="hlt">im</span> Rahmen des European Project for Ice Coring in Antarctica erwartet man vor allem neue Erkenntnisse über Klimawechselwirkungen zwischen den beiden Hemisphären und über die Ursachen der Variationen von Treibhausgaskonzentrationen parallel zu globalen Klimaschwankungen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24942204','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24942204"><span>Sequence-specific DNA alkylation by tandem Py-<span class="hlt">Im</span> polyamide conjugates.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Taylor, Rhys Dylan; Kawamoto, Yusuke; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi</p> <p>2014-09-01</p> <p>Tandem N-methylpyrrole-N-methylimidazole (Py-<span class="hlt">Im</span>) polyamides with good sequence-specific DNA-alkylating activities have been designed and synthesized. Three alkylating tandem Py-<span class="hlt">Im</span> polyamides with different linkers, which each contained the same moiety for the recognition of a 10 bp DNA sequence, were evaluated for their reactivity and selectivity by DNA alkylation, using high-resolution denaturing gel electrophoresis. All three conjugates displayed high reactivities for the target sequence. In particular, polyamide 1, which contained a β-alanine linker, displayed the most-selective sequence-specific alkylation towards the target 10 bp DNA sequence. The tandem Py-<span class="hlt">Im</span> polyamide conjugates displayed greater sequence-specific DNA alkylation than conventional hairpin Py-<span class="hlt">Im</span> polyamide conjugates (4 and 5). For further research, the design of tandem Py-<span class="hlt">Im</span> polyamide conjugates could play an important role in targeting specific gene sequences.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2013-09-16/pdf/2013-22390.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2013-09-16/pdf/2013-22390.pdf"><span>78 FR 56939 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2013-09-16</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on August 16, 2013, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. (``<span class="hlt">IMS</span> Global'') has filed written notifications...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2013-04-15/pdf/2013-08682.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2013-04-15/pdf/2013-08682.pdf"><span>78 FR 22297 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2013-04-15</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on March 19, 2013, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. (``<span class="hlt">IMS</span> Global'') has filed written notifications...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2012-11-06/pdf/2012-27106.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2012-11-06/pdf/2012-27106.pdf"><span>77 FR 66635 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; <span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2012-11-06</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on October 9, 2012, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. (``<span class="hlt">IMS</span> Global'') has filed written notifications...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004PhuZ...35..234G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004PhuZ...35..234G"><span>Falten und fliegen: Papierflieger und <span class="hlt">ihre</span> Physik</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gruber, Werner</p> <p>2004-09-01</p> <p>Mit Papierfliegern können wichtige Eigenschaften der Aerodynamik anschaulich vermittelt werden: ein Blatt Papier, ein paar Faltungen und schon kann man experimentieren. Allerdings sind beim Trimmen des Fliegers einige Punkte zu beachten. Besonders wichtig ist die Y-Stellung der Flügel, die ihm Flugstabilität verleiht. Ist der Flieger fertig, dann gilt es, die dem Modell am besten angepasste Wurftechnik herauszufinden. Dazu variiert man Wurfgeschwindigkeit und Abwurfwinkel. Den Boden kann ein Papierflieger auf vier prinzipiell verschiedenen Flugkurven erreichen: Optimal ist die Gerade, dann fliegt er am weitesten.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19770025251','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19770025251"><span><span class="hlt">IMS</span>/Satellite Situation Center report. Daily summary for <span class="hlt">IMS</span> high-altitude satellites, days 182-365 1977</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1977-01-01</p> <p>The orbital positions of a number of high-altitude satellites, capable of making magnetospheric measurements in the second half of 1977, are described. The following satellites are considered: Vela 5A, Vela 5B, Vela 6A, Vela 6B, Solrad 11A, Solrad 11B, Hawkeye 1, Prognoz 5, Explorer 47, Explorer 50, and ISEE-A/-B. The orbit elements used for generating the satellite ephemeris are shown. Complete presentations of the positions of these satellites for the second half of 1977 are given, as well as the <span class="hlt">IMS</span>/SSC special periods. Detailed plots illustrating these periods are provided. Time-ordered tables of magnetopause crossings, bow shock crossings, neutral sheet passes, midlatitude magnetotail passes, high-latitude magnetotail passes, and Hawkeye 1 northern cusp passes are presented. Bar charts covering the second half of 1977 are given which identify thirteen special periods (Nos. 10-22) based upon certain conjunctions of the high-altitude satellites.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2012-09-05/pdf/2012-21781.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2012-09-05/pdf/2012-21781.pdf"><span>77 FR 54611 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2012-09-05</p> <p>... Cooperative Research and Production Act of 1993--<span class="hlt">IMS</span> Global Learning Consortium, Inc. Notice is hereby given... Act of 1993, 15 U.S.C. 4301 et seq. (``the Act''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed... research project. Membership in this group research project remains open, and <span class="hlt">IMS</span> Global...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4701377','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4701377"><span>Platoon Interactions and Real-World Traffic Simulation and Validation Based on the LWR-<span class="hlt">IM</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ng, Kok Mun; Reaz, Mamun Bin Ibne</p> <p>2016-01-01</p> <p>Platoon based traffic flow models form the underlying theoretical framework in traffic simulation tools. They are essentially important in facilitating efficient performance calculation and evaluation in urban traffic networks. For this purpose, a new platoon-based macroscopic model called the LWR-<span class="hlt">IM</span> has been developed in [1]. Preliminary analytical validation conducted previously has proven the feasibility of the model. In this paper, the LWR-<span class="hlt">IM</span> is further enhanced with algorithms that describe platoon interactions in urban arterials. The LWR-<span class="hlt">IM</span> and the proposed platoon interaction algorithms are implemented in the real-world class I and class II urban arterials. Another purpose of the work is to perform quantitative validation to investigate the validity and ability of the LWR-<span class="hlt">IM</span> and its underlying algorithms to describe platoon interactions and simulate performance indices that closely resemble the real traffic situations. The quantitative validation of the LWR-<span class="hlt">IM</span> is achieved by performing a two-sampled t-test on queues simulated by the LWR-<span class="hlt">IM</span> and real queues observed at these real-world locations. The results reveal insignificant differences of simulated queues with real queues where the p-values produced concluded that the null hypothesis cannot be rejected. Thus, the quantitative validation further proved the validity of the LWR-<span class="hlt">IM</span> and the embedded platoon interactions algorithm for the intended purpose. PMID:26731745</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26731745','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26731745"><span>Platoon Interactions and Real-World Traffic Simulation and Validation Based on the LWR-<span class="hlt">IM</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ng, Kok Mun; Reaz, Mamun Bin Ibne</p> <p>2016-01-01</p> <p>Platoon based traffic flow models form the underlying theoretical framework in traffic simulation tools. They are essentially important in facilitating efficient performance calculation and evaluation in urban traffic networks. For this purpose, a new platoon-based macroscopic model called the LWR-<span class="hlt">IM</span> has been developed in [1]. Preliminary analytical validation conducted previously has proven the feasibility of the model. In this paper, the LWR-<span class="hlt">IM</span> is further enhanced with algorithms that describe platoon interactions in urban arterials. The LWR-<span class="hlt">IM</span> and the proposed platoon interaction algorithms are implemented in the real-world class I and class II urban arterials. Another purpose of the work is to perform quantitative validation to investigate the validity and ability of the LWR-<span class="hlt">IM</span> and its underlying algorithms to describe platoon interactions and simulate performance indices that closely resemble the real traffic situations. The quantitative validation of the LWR-<span class="hlt">IM</span> is achieved by performing a two-sampled t-test on queues simulated by the LWR-<span class="hlt">IM</span> and real queues observed at these real-world locations. The results reveal insignificant differences of simulated queues with real queues where the p-values produced concluded that the null hypothesis cannot be rejected. Thus, the quantitative validation further proved the validity of the LWR-<span class="hlt">IM</span> and the embedded platoon interactions algorithm for the intended purpose.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..1210773B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..1210773B"><span>Monitoring the Earth's Atmosphere with the Global <span class="hlt">IMS</span> Infrasound Network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Brachet, Nicolas; Brown, David; Mialle, Pierrick; Le Bras, Ronan; Coyne, John; Given, Jeffrey</p> <p>2010-05-01</p> <p>, they represent valuable data for other civil applications like monitoring of natural hazards (volcanic activity, storm tracking) and climate change. Non-noise detections are used in network processing at the IDC along with seismic and hydroacoustic technologies. The arrival phases detected on the three waveform technologies may be combined and used for locating events in an automatically generated bulletin of events. This automatic event bulletin is routinely reviewed by analysts during the interactive review process. However, the fusion of infrasound data with the other waveform technologies has only recently (in early 2010) become part of the IDC operational system, after a software development and testing period that began in 2004. The build-up of the <span class="hlt">IMS</span> infrasound network, the recent developments of the IDC infrasound software, and the progress accomplished during the last decade in the domain of real-time atmospheric modelling have allowed better understanding of infrasound signals and identification of a growing data set of ground-truth sources. These infragenic sources originate from natural or man-made sources. Some of the detected signals are emitted by local or regional phenomena recorded by a single <span class="hlt">IMS</span> infrasound station: man-made cultural activity, wind farms, aircraft, artillery exercises, ocean surf, thunderstorms, rumbling volcanoes, iceberg calving, aurora, avalanches. Other signals may be recorded by several <span class="hlt">IMS</span> infrasound stations at larger distances: ocean swell, sonic booms, and mountain associated waves. Only a small fraction of events meet the event definition criteria considering the Treaty verification mission of the Organization. Candidate event types for the IDC Reviewed Event Bulletin include atmospheric or surface explosions, meteor explosions, rocket launches, signals from large earthquakes and explosive volcanic eruptions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21182773','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21182773"><span>CDDO-<span class="hlt">Im</span> protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Reisman, Scott A.; Buckley, David B.; Tanaka, Yuji; Klaassen, Curtis D.</p> <p>2009-04-01</p> <p>CDDO-<span class="hlt">Im</span> is a synthetic triterpenoid recently shown to induce cytoprotective genes through the Nrf2-Keap1 pathway, an important mechanism for the induction of cytoprotective genes in response to oxidative stress. Upon oxidative or electrophilic insult, the transcription factor Nrf2 translocates to the nucleus, heterodimerizes with small Maf proteins, and binds to antioxidant response elements (AREs) in the upstream promoter regions of various cytoprotective genes. To further elucidate the hepatoprotective effects of CDDO-<span class="hlt">Im</span>, wild-type and Nrf2-null mice were pretreated with CDDO-<span class="hlt">Im</span> (1 mg/kg, i.p.) or vehicle (DMSO), and then administered acetaminophen (500 mg/kg, i.p.). Pretreatment of wild-type mice with CDDO-<span class="hlt">Im</span> reduced liver injury caused by acetaminophen. In contrast, hepatoprotection by CDDO-<span class="hlt">Im</span> was not observed in Nrf2-null mice. CDDO-<span class="hlt">Im</span> increased Nrf2 protein expression and Nrf2-ARE binding in wild-type, but not Nrf2-null mice. Furthermore, CDDO-<span class="hlt">Im</span> increased the mRNA expression of the Nrf2 target genes NAD(P)H: quinone oxidoreductase-1 (Nqo1); glutamate-cysteine ligase, catalytic subunit (Gclc); and heme-oxygenase-1 (Ho-1), in both a dose- and time-dependent manner. Conversely, CDDO-<span class="hlt">Im</span> did not induce Nqo1, Gclc, and Ho-1 mRNA expression in Nrf2-null mice. Collectively, the present study shows that CDDO-<span class="hlt">Im</span> pretreatment induces Nrf2-dependent cytoprotective genes and protects the liver from acetaminophen-induced hepatic injury.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27619644','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27619644"><span>A two-stage extraction procedure for insensitive munition (<span class="hlt">IM</span>) explosive compounds in soils.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Felt, Deborah; Gurtowski, Luke; Nestler, Catherine C; Johnson, Jared; Larson, Steven</p> <p>2016-12-01</p> <p>The Department of Defense (DoD) is developing a new category of insensitive munitions (<span class="hlt">IMs</span>) that are more resistant to detonation or promulgation from external stimuli than traditional munition formulations. The new explosive constituent compounds are 2,4-dinitroanisole (DNAN), nitroguanidine (NQ), and nitrotriazolone (NTO). The production and use of <span class="hlt">IM</span> formulations may result in interaction of <span class="hlt">IM</span> component compounds with soil. The chemical properties of these <span class="hlt">IM</span> compounds present unique challenges for extraction from environmental matrices such as soil. A two-stage extraction procedure was developed and tested using several soil types amended with known concentrations of <span class="hlt">IM</span> compounds. This procedure incorporates both an acidified phase and an organic phase to account for the chemical properties of the <span class="hlt">IM</span> compounds. The method detection limits (MDLs) for all <span class="hlt">IM</span> compounds in all soil types were <5 mg/kg and met non-regulatory risk-based Regional Screening Level (RSL) criteria for soil proposed by the U.S. Army Public Health Center. At defined environmentally relevant concentrations, the average recovery of each <span class="hlt">IM</span> compound in each soil type was consistent and greater than 85%. The two-stage extraction method decreased the influence of soil composition on <span class="hlt">IM</span> compound recovery. UV analysis of NTO established an isosbestic point based on varied pH at a detection wavelength of 341 nm. The two-stage soil extraction method is equally effective for traditional munition compounds, a potentially important point when examining soils exposed to both traditional and insensitive munitions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/976405','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/976405"><span>Large meteoroid detection using the global <span class="hlt">IMS</span> infrasound system</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>ReVelle, D. O.</p> <p>2002-01-01</p> <p>Numerous signals will be routinely detected using the 60 array, global <span class="hlt">IMS</span> (International Monitoring System) infrasound network. Infrasonic signals are sub-audible quasi longitudinal, atmospheric waves in the frequency band from about 10 Hz to -5 minutes in period (limited by human acoustic audibility in the high frequency limit and by the wave-guide acoustic cut-off frequency and the Brunt Vaisalla frequency in the low frequency limit) These small amplitude waves are a natural subset of the well-known atmospheric acoustic-gravity wave regime which has been identified from the linearized equations of geophysical fluid mechanics in the flat earth approximation, neglecting the earth's rotation, etc. For the <span class="hlt">IMS</span> network the instrumental pressure sensor response was chosen to range from -4 to 0.02 Hz. These are ground-based arrays of typically 4 to 9 sensors with separations of about 1-2 km between the array elements. Examples of naturally occurring impulsive sources of infrasound include volcanic eruptions, earthquakes, bolides (large meteor-fireballs entering the atmospheric at very high speeds up to -300 times faster than ground-level sound waves), microbaroms (the 'voice of the sea' due to the interaction of atmospheric storms and surface ocean waves) and the supersonic motion of the auroral electrojet at about 100 km altitude (auroral infrasonic waves), etc. In this paper we will briefly summarize our current state of knowledge of infrasound signals from bolides. This summary will include the generation of the signals at the complex, quasi-cylindrical line source, to the refraction and diffraction of the propagating waves by the middle atmospheric and tropospheric temperature and wind systems and finally, the detection of the signals and their interpretation by inferring the source properties, Le., source altitude, blast radius (see below) and the source energy, etc. In addition, we will use infrasound from energetic bolides to estimate the expected steady state</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25752029','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25752029"><span>[<span class="hlt">IM</span>/FM phase delay time measurement method of laser for TDLAS].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhang, Chao; Ma, Wei-Guang</p> <p>2014-11-01</p> <p>The present paper presents an method of using fiber Michelson interferometer to measure the Intensity-frequency (<span class="hlt">IM</span>/FM) phase delay change of the laser, it could realize the phase delay time measurement, while modulating the laser. Experimental results show that the laser output signal intensity-frequency (<span class="hlt">IM</span>/FM) phase delay of the laser has some differences from the theoretical value. The proposed method can be used to compensate for real-time signal strength-frequency (<span class="hlt">IM</span>/FM) phase delay effect on the gas concentration measurement results.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_8 --> <div id="page_9" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="161"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5333519','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5333519"><span>Membrane chaperoning by members of the PspA/<span class="hlt">IM</span>30 protein family</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Thurotte, Adrien; Brüser, Thomas; Mascher, Thorsten; Schneider, Dirk</p> <p>2017-01-01</p> <p>ABSTRACT PspA, <span class="hlt">IM</span>30 (Vipp1) and LiaH, which all belong to the PspA/<span class="hlt">IM</span>30 protein family, form high molecular weight oligomeric structures. For all proteins membrane binding and protection of the membrane structure and integrity has been shown or postulated. Here we discuss the possible membrane chaperoning activity of PspA, <span class="hlt">IM</span>30 and LiaH and propose that larger oligomeric structures bind to stressed membrane regions, followed by oligomer disassembly and membrane stabilization by protein monomers or smaller/different oligomeric scaffolds.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25812924','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25812924"><span>Subretinal Visual Implant Alpha <span class="hlt">IMS</span>--Clinical trial interim report.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stingl, Katarina; Bartz-Schmidt, Karl Ulrich; Besch, Dorothea; Chee, Caroline K; Cottriall, Charles L; Gekeler, Florian; Groppe, Markus; Jackson, Timothy L; MacLaren, Robert E; Koitschev, Assen; Kusnyerik, Akos; Neffendorf, James; Nemeth, Janos; Naeem, Mohamed Adheem Naser; Peters, Tobias; Ramsden, James D; Sachs, Helmut; Simpson, Andrew; Singh, Mandeep S; Wilhelm, Barbara; Wong, David; Zrenner, Eberhart</p> <p>2015-06-01</p> <p>A subretinal visual implant (Alpha <span class="hlt">IMS</span>, Retina Implant AG, Reutlingen, Germany) was implanted in 29 blind participants with outer retinal degeneration in an international multicenter clinical trial. Primary efficacy endpoints of the study protocol were a significant improvement of activities of daily living and mobility to be assessed by activities of daily living tasks, recognition tasks, mobility, or a combination thereof. Secondary efficacy endpoints were a significant improvement of visual acuity/light perception and/or object recognition (clinicaltrials.gov, NCT01024803). During up to 12 months observation time twenty-one participants (72%) reached the primary endpoints, of which thirteen participants (45%) reported restoration of visual function which they use in daily life. Additionally, detection, localization, and identification of objects were significantly better with the implant power switched on in the first 3 months. Twenty-five participants (86%) reached the secondary endpoints. Measurable grating acuity was up to 3.3 cycles per degree, visual acuities using standardized Landolt C-rings were 20/2000, 20/2000, 20/606 and 20/546. Maximal correct motion perception ranged from 3 to 35 degrees per second. These results show that subretinal implants can restore very-low-vision or low vision in blind (light perception or less) patients with end-stage hereditary retinal degenerations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=146384','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=146384"><span>IMGT, the international <span class="hlt">Im</span>MunoGeneTics database.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Giudicelli, V; Chaume, D; Bodmer, J; Müller, W; Busin, C; Marsh, S; Bontrop, R; Marc, L; Malik, A; Lefranc, M P</p> <p>1997-01-01</p> <p>IMGT, the international <span class="hlt">Im</span>MunoGeneTics database, is an integrated database specializing in immunoglobulins, T-cell receptors (TcR) and major histocompatibility complex (MHC) of all vertebrate species, initiated and co-ordinated by Marie-Paule Lefranc, CNRS, Montpellier II University, Montpellier, France (lefranc@ligm.crbm.cnrs-mop.fr). IMGT includes two databases: LIGM-DB (for immunoglobulins and TcR) and MHC/HLA-DB. IMGT comprises expertly annotated sequences and alignment tables. LIGM-DB contains more than 19 000 immunoglobulin and TcR sequences from 78 species. MHC/HLA-DB contains class I and class II human leukocyte antigen alignment tables. An IMGT tool, DNAPLOT, developed for immunoglobulins, TcR and MHC sequence alignments, is also available. IMGT works in close collaboration with the EMBL database. IMGT goals are to establish a common data access to all immunogenetics data, including sequences, oligonucleotide primers, gene maps and other genetic data of immunoglobulins, TcR and MHC molecules, and to provide a graphical user-friendly data access. IMGT will have important implications in medical research (repertoire in autoimmune diseases, AIDS, leukemias, lymphomas), therapeutical approaches (antibody engineering), genome diversity and genome evolution studies. IMGT can be accessed at http://imgt.cnusc.fr:8104 and http://www.ebi.ac.uk/IMGT PMID:9016537</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19770038491&hterms=review+international+studies&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dreview%2Binternational%2Bstudies','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19770038491&hterms=review+international+studies&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dreview%2Binternational%2Bstudies"><span>The <span class="hlt">IMS</span> Satellite Situation Center. [International Magnetospheric Study</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Sugiura, M.; Vette, J. I.</p> <p>1977-01-01</p> <p>Following a brief historical review of the SSC (Satellite Situation Center), created by the U.S. for the <span class="hlt">IMS</span> (International Magnetospheric Study), its main functions are discussed. The services of the SSC include the accurate orbit determination of the satellites, 12-18 months in advance and the coordination of simultaneous observations by a multispacecraft system, which are essential for the optimization of the scientific gains from experiments conducted with limited resources. For 1976 SSC generated plots of the satellites Vela 5B, Vela 6A, Vela 6B, Hawkeye 1, Imp H (7), Imp J (8) by computing certain projections of the solar ecliptic, solar magnetospheric, and solar magnetic coordinate systems. The SSC system was automated by the addition of a computer system capable of interactive graphics. The SSC can also provide the ground-based campaigns with a graphical or tabular information about the position low-altitude satellites in any coordinate system. The possible participation of the SSC in future Electrodynamics Explorer mission, Space Shuttle programs is also being explored.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/378791','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/378791"><span>Evaluation of infrasonic detection capability for the CTBT/<span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Armstrong, W.T.; Whitaker, R.W.; Olson, J.V.</p> <p>1996-09-01</p> <p>Evaluation of infrasonic detection capability for the International Monitoring System of the Comprehensive Test Ban Treaty (<span class="hlt">IMS</span>/CTBT) is made with respect to signal analysis and global coverage. Signal analysis is anecdotally reviewed with respect to composite power, correlation and F-statistic detection algorithms. In the absence of adaptive pre-filtering, either cross-correlation or F-statistic detection is required. As an unbounded quantity, the F-statistic offers potentially greater sensitivity to signals of interest. With PURE state pre-filtering, power detection begins to become competitive with correlation and F-statistic detection. Additional application of simple post-filters of minimum duration and maximum bearing deviation results in unique positive detection of an identified impulsive infrasonic signal. Global coverage estimates are performed as a useful deterministic evaluation of networks, offering an easily interpreted network performance, which compliments previous probabilistic network evaluations. In particular, adequate coverage (2 sites), uniform coverage, and redundant coverage (3 to 4 sites) provide figures of merit in evaluating detection, location and vulnerability, respectively. Coverage estimates of the I60 network have been performed which indicate generally adequate coverage for the majority of the globe. Modest increase of station gain (increase of number of elements from 4 to 7) results in significant increase in coverage for mean signal values. Ineffective sites and vulnerability sites are identified which suggest further refinement of the network is possible.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12951376','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12951376"><span>The <span class="hlt">IMS</span> Act 1992: need for more amendments and publicity.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tiwari, Satish Kamtaprasad; Chaturvedi, Pushpa</p> <p>2003-08-01</p> <p>The <span class="hlt">IMS</span> act was passed after a lot of thinking, discussions over pros and cons of childhood feeding practices and recommendations of WHA. We are not only legally bound by it, but it is also our moral responsibility to see that the act works. Already 9-10 years have passed but the results are not that encouraging. Most of our colleagues are unaware of the provisions and importance of this act. Making the law effective is very time consuming, costly, unaffordable and avoidable affair. We should not harp on multiplicity of legal opinions & loopholes to allow breaking the law in spirit if not in letter. We feel that most of our laws are paper tigers without any teeth, gathering dust by remaining present only in law books or journals. If we don't act now then there is every possibility that this act may also become one of the historical legal documents. Hence it is time for all of us to become an activist or counselor for BF. We should create awareness and public opinion about protection, promotion and support for BF. Be vigilant, form community watch group and report violations to the authorities. So that our country can become a proud nation of healthy, intelligent and emotionally stable children in the 21st century.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23106218','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23106218"><span>Synthesis of cyclic Py-<span class="hlt">Im</span> polyamide libraries.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Benjamin C; Montgomery, David C; Puckett, James W; Dervan, Peter B</p> <p>2013-01-04</p> <p>Cyclic Py-<span class="hlt">Im</span> polyamides containing two GABA turn units exhibit enhanced DNA binding affinity, but extensive studies of their biological properties have been hindered due to synthetic inaccessibility. A facile modular approach toward cyclic polyamides has been developed via microwave-assisted solid-phase synthesis of hairpin amino acid oligomer intermediates followed by macrocyclization. A focused library of cyclic polyamides 1-7 targeted to the androgen response element (ARE) and the estrogen response element (ERE) were synthesized in 12-17% overall yield. The Fmoc protection strategy also allows for selective modifications on the GABA turn units that have been shown to improve cellular uptake properties. The DNA binding affinities of a library of cyclic polyamides were measured by DNA thermal denaturation assays and compared to the corresponding hairpin polyamides. Fluorescein-labeled cyclic polyamides have been synthesized and imaged via confocal microscopy in A549 and T47D cell lines. The IC(50) values of compounds 1-7 and 9-11 were determined, revealing remarkably varying levels of cytotoxicity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25711379','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25711379"><span>Dynamic hydrogen bonding and DNA flexibility in minor groove binders: molecular dynamics simulation of the polyamide f-<span class="hlt">ImPyIm</span> bound to the Mlu1 (MCB) sequence 5'-ACGCGT-3' in 2:1 motif.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bruce, Chrystal D; Ferrara, Maddi M; Manka, Julie L; Davis, Zachary S; Register, Janna</p> <p>2015-05-01</p> <p>Molecular dynamics simulations of the DNA 10-mer 5'-CCACGCGTGG-3' alone and complexed with the formamido-imidazole-pyrrole-imidazole (f-<span class="hlt">ImPyIm</span>) polyamide minor groove binder in a 2:1 fashion were conducted for 50 ns using the pbsc0 parameters within the AMBER 12 software package. The change in DNA structure upon binding of f-<span class="hlt">ImPyIm</span> was evaluated via minor groove width and depth, base pair parameters of Slide, Twist, Roll, Stretch, Stagger, Opening, Propeller, and x-displacement, dihedral angle distributions of ζ, ε, α, and γ determined using the Curves+ software program, and hydrogen bond formation. The dynamic hydrogen bonding between the f-<span class="hlt">ImPyIm</span> and its cognate DNA sequence was compared to the static image used to predict sequence recognition by polyamide minor groove binders. Many of the predicted hydrogen bonds were present in less than 50% of the simulation; however, persistent hydrogen bonds between G5/15 and the formamido group of f-<span class="hlt">ImPyIm</span> were observed. It was determined that the DNA is wider in the Complex than without the polyamide binder; however, there is flexibility in this particular sequence, even in the presence of the f-<span class="hlt">ImPyIm</span> as evidenced by the range of minor groove widths the DNA exhibits and the dynamics of the hydrogen bonding that binds the two f-<span class="hlt">ImPyIm</span> ions to the minor groove. The Complex consisting of the DNA and the 2 f-<span class="hlt">ImPyIm</span> binders shows slight fraying of the 5' end of the 10-mer at the end of the simulation, but the portion of the oligomer responsible for recognition and binding is stable throughout the simulation. Several structural changes in the Complex indicate that minor groove binders may have a more active role in inhibiting transcription than just preventing binding of important transcription factors.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060016374&hterms=current+events&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D80%26Ntt%3Dcurrent%2Bevents','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060016374&hterms=current+events&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D80%26Ntt%3Dcurrent%2Bevents"><span>Analyzing Electric Field Morphology Through Data-Model Comparisons of the GEM <span class="hlt">IM/S</span> Assessment Challenge Events</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Liemohn, Michael W.; Ridley, Aaron J.; Kozyra, Janet U.; Gallagher, Dennis L.; Thomsen, Michelle F.; Henderson, Michael G.; Denton, Michael H.; Brandt, Pontus C.; Goldstein, Jerry</p> <p>2006-01-01</p> <p>The storm-time inner magnetospheric electric field morphology and dynamics are assessed by comparing numerical modeling results of the plasmasphere and ring current with many in situ and remote sensing data sets. Two magnetic storms are analyzed, April 22,2001 and October 21-23,2001, which are the events selected for the Geospace Environment Modeling (GEM) Inner Magnetosphere/Storms (<span class="hlt">IM/S</span>) Assessment Challenge (IMSAC). The IMSAC seeks to quantify the accuracy of inner magnetospheric models as well as synthesize our understanding of this region. For each storm, the ring current-atmosphere interaction model (RAM) and the dynamic global core plasma model (DGCPM) were run together with various settings for the large-scale convection electric field and the nightside ionospheric conductance. DGCPM plasmaspheric parameters were compared with IMAGE-EUV plasmapause extractions and LANL-MPA plume locations and velocities. RAM parameters were compared with Dst*, LANL-MPA fluxes and moments, IMAGE-MENA images, and IMAGE-HENA images. Both qualitative and quantitative comparisons were made to determine the electric field morphology that allows the model results to best fit the plasma data at various times during these events. The simulations with self-consistent electric fields were, in general, better than those with prescribed field choices. This indicates that the time-dependent modulation of the inner magnetospheric electric fields by the nightside ionosphere is quite significant for accurate determination of these fields (and their effects). It was determined that a shielded Volland-Stern field description driven by the 3-hour Kp index yields accurate results much of the time, but can be quite inconsistent. The modified Mcllwain field description clearly lagged in overall accuracy compared to the other fields, but matched some data sets (like Dst*) quite well. The rankings between the simulations varied depending on the storm and the individual data sets, indicating that</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060016374&hterms=morphology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dmorphology','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060016374&hterms=morphology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dmorphology"><span>Analyzing Electric Field Morphology Through Data-Model Comparisons of the GEM <span class="hlt">IM/S</span> Assessment Challenge Events</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Liemohn, Michael W.; Ridley, Aaron J.; Kozyra, Janet U.; Gallagher, Dennis L.; Thomsen, Michelle F.; Henderson, Michael G.; Denton, Michael H.; Brandt, Pontus C.; Goldstein, Jerry</p> <p>2006-01-01</p> <p>The storm-time inner magnetospheric electric field morphology and dynamics are assessed by comparing numerical modeling results of the plasmasphere and ring current with many in situ and remote sensing data sets. Two magnetic storms are analyzed, April 22,2001 and October 21-23,2001, which are the events selected for the Geospace Environment Modeling (GEM) Inner Magnetosphere/Storms (<span class="hlt">IM/S</span>) Assessment Challenge (IMSAC). The IMSAC seeks to quantify the accuracy of inner magnetospheric models as well as synthesize our understanding of this region. For each storm, the ring current-atmosphere interaction model (RAM) and the dynamic global core plasma model (DGCPM) were run together with various settings for the large-scale convection electric field and the nightside ionospheric conductance. DGCPM plasmaspheric parameters were compared with IMAGE-EUV plasmapause extractions and LANL-MPA plume locations and velocities. RAM parameters were compared with Dst*, LANL-MPA fluxes and moments, IMAGE-MENA images, and IMAGE-HENA images. Both qualitative and quantitative comparisons were made to determine the electric field morphology that allows the model results to best fit the plasma data at various times during these events. The simulations with self-consistent electric fields were, in general, better than those with prescribed field choices. This indicates that the time-dependent modulation of the inner magnetospheric electric fields by the nightside ionosphere is quite significant for accurate determination of these fields (and their effects). It was determined that a shielded Volland-Stern field description driven by the 3-hour Kp index yields accurate results much of the time, but can be quite inconsistent. The modified Mcllwain field description clearly lagged in overall accuracy compared to the other fields, but matched some data sets (like Dst*) quite well. The rankings between the simulations varied depending on the storm and the individual data sets, indicating that</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27836697','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27836697"><span>The <span class="hlt">IM</span>30/Vipp1 C-terminus associates with the lipid bilayer and modulates membrane fusion.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hennig, Raoul; West, Ana; Debus, Martina; Saur, Michael; Markl, Jürgen; Sachs, Jonathan N; Schneider, Dirk</p> <p>2017-02-01</p> <p><span class="hlt">IM</span>30/Vipp1 proteins are crucial for thylakoid membrane biogenesis in chloroplasts and cyanobacteria. A characteristic C-terminal extension distinguishes these proteins from the homologous bacterial PspA proteins, and this extension has been discussed to be key for the <span class="hlt">IM</span>30/Vipp1 activity. Here we report that the extension of the Synechocystis <span class="hlt">IM</span>30 protein is indispensable, and argue that both, the N-terminal PspA-domain as well as the C-terminal extension are needed in order for the <span class="hlt">IM</span>30 protein to conduct its in vivo function. In vitro, we show that the PspA-domain of <span class="hlt">IM</span>30 is vital for stability/folding and oligomer formation of <span class="hlt">IM</span>30 as well as for <span class="hlt">IM</span>30-triggered membrane fusion. In contrast, the <span class="hlt">IM</span>30 C-terminal domain is involved in and necessary to stabilize defined contacts to negatively charged membrane surfaces, and to modulate the <span class="hlt">IM</span>30-induced membrane fusion activity. Although the two <span class="hlt">IM</span>30 protein domains have distinct functional roles, only together they enable <span class="hlt">IM</span>30 to work properly.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013pkk..book..213F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013pkk..book..213F"><span>“&ldots;how the right technique emerged at the right time” Zur Geschichte der fotografischen Methode <span class="hlt">im</span> Kalten Krieg</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Fengler, Silke</p> <p></p> <p>Die Frühgeschichte der fotografischen Methode, die als Nachweisinstrument kernphysikalischer und kosmischer Strahlung in den 1950er Jahren zur Blüte kam, hat das Interesse vieler Wissenschaftshistoriker gefunden. Peter Galison hat gezeigt, wie fragil das Experimentalsystem lange Zeit war, das sich um die Methode bildete, und wie prekär die mit <span class="hlt">ihr</span> aufgezeichneten Ergebnisse.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997SPIE.2910...93H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997SPIE.2910...93H"><span>Global R&D through the Intelligent Manufacturing Systems (<span class="hlt">IMS</span>) program</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Huray, Paul G.</p> <p>1997-01-01</p> <p>The industry-led, international intelligent manufacturing systems (<span class="hlt">IMS</span>) program provides a special vehicle for joint research and development between government, industry and academia in the United States, Canada, Japan, Australia, and Europe. Since its beginning in 1989, the <span class="hlt">IMS</span> program has progressed through a feasibility phase which demonstrated that international legal barriers, trade issues, and intellectual property problems could be overcome. The program is constructed to provide higher quality design, customized products, shorter delivery cycles and lower costs. Interactions between partner companies have led to new business opportunities for mutual profit and some claim to have learned strategic information about their international competitors. The <span class="hlt">IMS</span> program is growing through the participation of hundreds of corporate and university partners who share responsibilities in specific projects and jointly reap benefits for their manufacturing products and processes. The logic for choosing or not choosing the <span class="hlt">IMS</span> mechanisms will be discussed and R and D projects will be identified.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=62645&keyword=positive+AND+education&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89913774&CFTOKEN=82624618','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=62645&keyword=positive+AND+education&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89913774&CFTOKEN=82624618"><span>CRYPTOSPORIDIUM OOCYST RECOVERY IN WATER BY EPA METHOD 1623: EVALUATION OF A MODIFIED <span class="hlt">IMS</span> DISSOCIATION</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>EPA Methods 1622 and 1623 are the benchmarks for detection of Cryptosporidium spp. oocysts in water. These methods consist of filtration, elution, purification by immunomagnetic separation (<span class="hlt">IMS</span>), and microscopic analysis after staining with a fluorescein isothiocyanate conjugate...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22362169','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22362169"><span>A facile synthesis of cubic (<span class="hlt">Im</span>3m) alumina films on glass with potential catalytic activity.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mitra, Anuradha; Jana, Debrina; De, Goutam</p> <p>2012-04-04</p> <p>Thermally stable phase pure mesoporous cubic (<span class="hlt">Im</span>3m) alumina films were synthesized on glass substrates under ambient conditions. These cubic alumina films incorporated with Au NPs exhibited excellent catalytic property.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009mmos.book....1D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009mmos.book....1D"><span>A Base Solution for Exposing <span class="hlt">IMS</span> Telecommunication Services to Web 2.0 Enabled Applications</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Deinert, Florian; Murarasu, Alin; Bachmann, Andreas; Magedanz, Thomas</p> <p></p> <p>The convergence of telecommunication and Web 2.0 services is leading to new opportunities for the telecommunications market. Companies are looking for ways to include their services in Web 2.0 applications. Predictions suggest that future telecommunication networks will be based on the IP Multimedia Subsystem (<span class="hlt">IMS</span>), an all IP telecommunication core network. This paper describes an approach to combining Web 2.0 enabled applications, namely widgets, with telecommunication features using <span class="hlt">IMS</span>. Widgets are small applications based on Web technologies that run on the client device. A new abstraction layer with interfaces for the different telecommunication features will be introduced. In addition a widget engine that makes these telecommunication interfaces available to its widgets will be presented. This will allow the rapid development of <span class="hlt">IMS</span> applications for external developers and the combination of other Web 2.0 services with <span class="hlt">IMS</span> features.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26616427','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26616427"><span>EM∩<span class="hlt">IM</span>: software for relating ion mobility mass spectrometry and electron microscopy data.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Degiacomi, Matteo T; Benesch, Justin L P</p> <p>2016-01-07</p> <p>We present EM∩<span class="hlt">IM</span>, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩<span class="hlt">IM</span> thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25623757','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25623757"><span>A blue luminescent MOF as a rapid turn-off/turn-on detector for H2O, O2 and CH2Cl2, MeCN: ∞³[Ce(<span class="hlt">Im</span>)3<span class="hlt">ImH]·Im</span>H.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Meyer, L V; Schönfeld, F; Zurawski, A; Mai, M; Feldmann, C; Müller-Buschbaum, K</p> <p>2015-03-07</p> <p>The blue emitting luminescent MOF ∞³[Ce(<span class="hlt">Im</span>)3<span class="hlt">ImH]·Im</span>H forms a 3D-framework with Kagomé net topology. The framework exhibits an intense blue luminescence which can be retained upon activation of the MOF with the formula ∞³[Ce(<span class="hlt">Im</span>)3<span class="hlt">Im</span>H]. The luminescence is metal-based due to parity-allowed 5d-4f-transitions. Time-dependent investigations of the interaction with liquid and gas analytes show that the MOF – by utilising 5d-4f-transitions of Ce(3+) – can be used as a high-speed "turn-off" detector for water and oxygen in dry air. Other protic or polar solvents, like methanol, acetone or pyridine, which also show a "turn-off"-effect can be distinguished from water-detection either on a time scale (ranging up to 250,000 : 1) or a shift of the chromaticity, the latter being pronounced for MeOH. The fast time-dependent decrease of the luminescence intensity for water arises from an extremely fast hydrolysis and is irreversible. Polar aprotic molecules like dichloromethane and acetonitrile can also result in a "turn-on"-effect of the luminescence intensity due to their behaviour as additional sensitizers for Ce(3+)-emission. We conclude that the cerium-MOF can be utilised in gas and liquid sensing applications as a detector material for water and oxygen in dry air. The luminescence is intense with good quantum yield between 55% (as-synthesised) and 36% (activated). This implies that only milligram amounts of the material are needed to detect the analyte species and is especially useful, as the MOF can be directly used as-synthesised for water detection in applications for which an irreversible signal change is desired, e.g. preventing a signal change upon unwanted re-drying.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25977065','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25977065"><span>Determination of volatile compounds by GC-<span class="hlt">IMS</span> to assign the quality of virgin olive oil.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Garrido-Delgado, Rocío; Dobao-Prieto, María del Mar; Arce, Lourdes; Valcárcel, Miguel</p> <p>2015-11-15</p> <p>The characterisation of different olive oil categories (extra virgin, virgin and lampante) using Ion Mobility Spectrometry (<span class="hlt">IMS</span>) was improved by replacing the multicapillary column (MCC) with a capillary column (CC). The data obtained with MCC-<span class="hlt">IMS</span> and CC-<span class="hlt">IMS</span> were evaluated, studying both the global and the specific information obtained after the analysis of the volatile fraction of olive oils. A better differentiation of the oil categories was obtained employing CC vs MCC, since the classification percentage obtained with the CC-<span class="hlt">IMS</span> was 92% as opposed to 87% obtained with MCC-<span class="hlt">IMS</span>; although in productivity analytical terms, MCC offer a faster analysis than GC. The specific information obtained was also used to build a database, with a view to facilitating the characterization of specific attributes of olive oils. A total of 26 volatile metabolites (aldehydes, ketones, alcohols and esters) were identified. Finally, as revealed by an ANOVA test, some volatiles differed markedly in content among the different categories of oil. The data obtained confirms the potential of <span class="hlt">IMS</span> as a reliable analytical screening technique, which can be used to assign the correct category to an olive oil sample.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=179612','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=179612"><span>The Helicobacter pylori genome is modified at CATG by the product of hpy<span class="hlt">IM</span>.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Xu, Q; Peek, R M; Miller, G G; Blaser, M J</p> <p>1997-01-01</p> <p>To understand mechanisms of DNA methylation in Helicobacter pylori, a human pathogen associated with peptic ulcer disease and gastric adenocarcinoma, we cloned a putative DNA methyltransferase gene, hpy<span class="hlt">IM</span>. This gene contains a 990-bp open reading frame encoding a 329-amino-acid protein, M.HpyI. Sequence analysis revealed that M.HpyI was closely related to CATG-recognizing adenine DNA methyltransferases, including M.NlaIII in N. lactamica. hpy<span class="hlt">IM</span> was present in all H. pylori strains tested. DNA from wild-type H. pylori strains was resistant to digestion by SphI and NlaIII, which recognize DNA at sites containing CATG, whereas their isogenic hpy<span class="hlt">IM</span> mutants were susceptible, indicating lack of modification. Overexpression of hpy<span class="hlt">IM</span> in Escherichia coli rendered DNA from these cells resistant to NlaIII digestion, confirming the role of hpy<span class="hlt">IM</span> in modifying CATG sites. We conclude that hpy<span class="hlt">IM</span> encodes a DNA methyltransferase, M.HpyI, that is well conserved among diverse H. pylori strains and that modifies H. pylori genomes at CATG sites. PMID:9352933</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_9 --> <div id="page_10" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="181"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24620419','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24620419"><span>A critical analysis of Sorrell v. <span class="hlt">IMS</span> Health, Inc.: Pandora's box at best.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bibet-Kalinyak, Isabelle</p> <p>2012-01-01</p> <p>Sorrell v. <span class="hlt">IMS</span> Health, Inc. ("<span class="hlt">IMS</span> Health"), a remarkable health care case with resounding First Amendment and economic repercussions, features the clashing interests of the State of Vermont and aggressive free market players from the pharmaceutical and data mining industries in a constitutional battle over Free Speech. In 2007, Vermont enacted Act 80, The Confidentiality of Prescription Information Act, prohibiting the sale, disclosure, and use of pharmacy records. Together with two other data miners and PhRMA, an association of brand-name drug manufacturers, <span class="hlt">IMS</span> Health successfully challenged the constitutionality of Act 80 on First Amendment grounds. This article examines the legal arguments of <span class="hlt">IMS</span> Health and Act 80 and analyzes why <span class="hlt">IMS</span> Health stands out for potentially challenging the traditional doctrine of commercial speech and the resulting legal implications. After reviewing the Supreme Court's reasoning, the article concludes that, although the Supreme Court reached the appropriate outcome, it did so by unjustifiably departing from the established legal doctrine of commercial speech and the American tradition of consumer protection. At best, <span class="hlt">IMS</span> Health's reasoning opens a legal Pandora's Box potentially leading to an onset of new commercial speech challenges; at worst, it manufactured a Trojan Horse aimed at eroding the traditional regulatory safeguards that maintain a balance between the needs of consumers and corporations alike.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21940641','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21940641"><span><span class="hlt">Im</span>OSM: intermittent evolution and robustness of phylogenetic methods.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Thi Nguyen, Minh Anh; Gesell, Tanja; von Haeseler, Arndt</p> <p>2012-02-01</p> <p>Among the criteria to evaluate the performance of a phylogenetic method, robustness to model violation is of particular practical importance as complete a priori knowledge of evolutionary processes is typically unavailable. For studies of robustness in phylogenetic inference, a utility to add well-defined model violations to the simulated data would be helpful. We therefore introduce <span class="hlt">Im</span>OSM, a tool to imbed intermittent evolution as model violation into an alignment. Intermittent evolution refers to extra substitutions occurring randomly on branches of a tree, thus changing alignment site patterns. This means that the extra substitutions are placed on the tree after the typical process of sequence evolution is completed. We then study the robustness of widely used phylogenetic methods: maximum likelihood (ML), maximum parsimony (MP), and a distance-based method (BIONJ) to various scenarios of model violation. Violation of rates across sites (RaS) heterogeneity and simultaneous violation of RaS and the transition/transversion ratio on two nonadjacent external branches hinder all the methods recovery of the true topology for a four-taxon tree. For an eight-taxon balanced tree, the violations cause each of the three methods to infer a different topology. Both ML and MP fail, whereas BIONJ, which calculates the distances based on the ML estimated parameters, reconstructs the true tree. Finally, we report that a test of model homogeneity and goodness of fit tests have enough power to detect such model violations. The outcome of the tests can help to actually gain confidence in the inferred trees. Therefore, we recommend using these tests in practical phylogenetic analyses.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16207311','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16207311"><span>Pharmacokinetics of azithromycin after i.v. and <span class="hlt">i.m</span>. administration to sheep.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cárceles, C M; Font, A; Escudero, E; Espuny, A; Marín, P; Fernández-Varón, E</p> <p>2005-10-01</p> <p>The pharmacokinetics (PK) of azithromycin after i.v. and <span class="hlt">i.m</span>. injection at a single dosage of 20 mg/kg bodyweight was studied in sheep. Blood samples were collected from the jugular vein until 120 h after dosing for both routes. Plasma concentrations of azithromycin were determined by bioassay. The plasma concentration-time data of azithromycin best fitted a three-compartment model after i.v. administration and a two-compartment model with first-order absorption after <span class="hlt">i.m</span>. administration. The elimination half-life (t(1/2lambdaz)) was 47.70 +/- 7.49 h after i.v. administration and 61.29 +/- 13.86 h after <span class="hlt">i.m</span>. administration. Clearance value after i.v. dosing was 0.52 +/- 0.08 L/kg.h. After <span class="hlt">i.m</span>. administration a peak azithromycin concentration (C(max)) of 1.26 +/- 0.19 mg/L was achieved at 1.24 +/- 0.31 h (t(max)). Area under the curve (AUC) were 38.85 +/- 5.83 mg.h/L and 36.03 +/- 1.52 mg.h/L after i.v. and <span class="hlt">i.m</span>. administration respectively. Bioavailability obtained after <span class="hlt">i.m</span>. administration was 94.08 +/- 11.56%. The high tolerability of this <span class="hlt">i.m</span>. preparation and the favourable PK behaviour such as the long half-life and high bioavailability make azithromycin likely to be effective in sheep.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26872610','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26872610"><span>2016 <span class="hlt">IMS</span> Recommendations on women's midlife health and menopause hormone therapy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Baber, R J; Panay, N; Fenton, A</p> <p>2016-04-01</p> <p>The International Menopause Society (<span class="hlt">IMS</span>) has produced these new 2016 recommendations on women's midlife health and menopause hormone therapy (MHT) to help guide health-care professionals in optimizing their management of women in the menopause transition and beyond. The term MHT has been used to cover therapies including estrogens, progestogens and combined regimens. For the first time, the 2016 <span class="hlt">IMS</span> recommendations now include grades of recommendations, levels of evidence and 'good practice points', in addition to section-specific references. Where possible, the recommendations are based on and linked to the evidence that supports them, unless good-quality evidence is absent. Particular attention has been paid to published evidence from 2013 onwards, the last time the <span class="hlt">IMS</span> recommendations were updated. Databases have been extensively searched for relevant publications using key terms specific to each specialist area within menopause physiology and medicine. Information has also been drawn from international consensus statements published by bodies such as the <span class="hlt">IMS</span>, the European Menopause and Andropause Society and the North American Menopause Society. The recommendations have been produced by experts derived mainly from the <span class="hlt">IMS</span>, with the assistance of key collaborators where deemed advantageous. In preparing these international recommendations, experts have taken into account geographical variations in medical care, prevalence of diseases, and country-specific attitudes of the public, medical community and health authorities towards menopause management. The variation in availability and licensing of MHT and other products has also been considered.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026865','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026865"><span>Data collection in <span class="hlt">IMS</span>: It's not as easy as it looks</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Davis, Dennis M.; Maswadeh, Waleed; Shoff, Donald B.; Harden, Charles S.; Snyder, A. Peter</p> <p>1995-01-01</p> <p>Data collection in Ion Mobility Spectrometry (<span class="hlt">IMS</span>) is not as easy an endeavor as it appears. Despite the advent of high speed personal computers and fast analog-to-digital converters (ADC's), care must be taken to ensure that reliable data are obtained in a timely fashion. This is especially true in hyphenated techniques, e.g. GC-<span class="hlt">IMS</span>, where the amount of data increases dramatically when gas chromatography-ion mobility spectrometry (GC-<span class="hlt">IMS</span>) data is being collected. Using the Graseby GC-<span class="hlt">IMS</span>, with a gate repetition rate of 33 Hz, it is theoretically possible to collect 33 spectra per second. This collection rate is not realistically obtained due to a number of factors. Among these factors are inaccuracy of the timing signal from the <span class="hlt">IMS</span>, the necessity to store the data, disk input/output limitations, disk operating system limitations, and program overhead. Taking these factors into account, we have achieved a data collection rate of 20 spectra per second. This paper will describe these problems, demonstrate the practical effects these problems present, and present methods for minimizing these effects.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19904990','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19904990"><span>Petroleum crude oil characterization by <span class="hlt">IMS</span>-MS and FTICR MS.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernandez-Lima, Francisco A; Becker, Christopher; McKenna, Amy M; Rodgers, Ryan P; Marshall, Alan G; Russell, David H</p> <p>2009-12-15</p> <p>Here, complementary ion mobility/mass spectrometry (<span class="hlt">IM</span>/MS) and ultrahigh-resolution Fourier transform ion cyclotron resonance (FTICR) MS analyses of light, medium, and heavy petroleum crude oils yielded distributions of the heteroatom-containing hydrocarbons, as well as multiple conformational classes. The <span class="hlt">IM</span>/MS technique provides unique fingerprints for fast identification of signature conformational/compositional patterns, whereas FTICR MS analysis provides comprehensive heteroatom class distributions. <span class="hlt">IM</span>/MS and FTICR MS results reveal an increase in compositional complexity in proceeding from light to medium to heavy crude oils. Inspection of the mobility results shows a high structural diversity for the C(n)H(h)XY (XY = N(1), S(1), N(1), O(1), NS, SO(1-2), NO(1-2), etc.) series, as well as a shift from planar to more compact three-dimensional structures with increasing mass.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3377982','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3377982"><span>Monitoring the inflammatory response to infection through the integration of MALDI <span class="hlt">IMS</span> and MRI</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Attia, Ahmed S.; Schroeder, Kaitlin A.; Seeley, Erin H.; Wilson, Kevin J.; Hammer, Neal D.; Colvin, Daniel C.; Manier, M. Lisa; Nicklay, Joshua J.; Rose, Kristie L.; Gore, John C.; Caprioli, Richard M.; Skaar, Eric P.</p> <p>2012-01-01</p> <p>SUMMARY Systemic bacterial infection is characterized by a robust whole organism inflammatory response. Analysis of the immune response to infection involves technologies that typically focus on single organ systems and lack spatial information. Additionally, the analysis of individual inflammatory proteins requires antibodies specific to the protein of interest, limiting the panel of proteins that can be analyzed. Herein we describe the application of matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI <span class="hlt">IMS</span>) to mice systemically infected with Staphylococcus aureus to identify inflammatory protein masses that respond to infection throughout an entire infected animal. Integrating the resolution afforded by magnetic resonance imaging (MRI) with the sensitivity of MALDI <span class="hlt">IMS</span> provides three-dimensional spatially resolved information regarding the distribution of innate immune proteins during systemic infection, allowing comparisons to in vivo structural information and soft tissue contrast via MRI. Thus, integrating MALDI <span class="hlt">IMS</span> with MRI provides a systems biology approach to study inflammation during infection. PMID:22704626</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19880009668','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19880009668"><span>Suggested severe local storm operational scenario for GOES <span class="hlt">I-M</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Shenk, William E.; Mosher, Fredrick</p> <p>1987-01-01</p> <p>The GOES <span class="hlt">I-M</span> satellite system is expected to provide continuous high resolution estimates of temperature and moisture profiles, winds from cloud motions, surface temperature, cloud properties, and precipitation for severe local storm and tropical cyclone events. The suggested operational schedule for the GOES <span class="hlt">I-M</span> satellite emphasizes the observation frequencies, spatial coverage, spectral bands, etc. for the GOES <span class="hlt">I-M</span> imager and sounder instruments that are expected to optimize the determination of the relevant meteorological parameters. During severe local storm events, the imager would be programmed to perform high frequency imaging (less than or= 3.5 min) for determining winds from cloud motions and for monitoring severe convection. In addition, the sounder would provide temperature and moisture profiles every hour over a 3000 X 3000 km domain during the antecedent stage or over a 1000 X 1000 km area every 10 minutes during the mature storm stage.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..1614482B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..1614482B"><span>An <span class="hlt">IMS</span> Station life cycle from a sustainment point of view</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Brely, Natalie; Gautier, Jean-Pierre; Foster, Daniel</p> <p>2014-05-01</p> <p>The International Monitoring System (<span class="hlt">IMS</span>) is to consist of 321 monitoring facilities, composed of four different technologies with a variety of designs and equipment types, deployed in a range of environments around the globe. The International Monitoring System is conceived to operate in perpetuity through maintenance, replacement and recapitalization of <span class="hlt">IMS</span> facilities' infrastructure and equipment when the end of service life is reached [CTBT/PTS/INF.1163]. Life Cycle techniques and modellization are being used by the PTS to plan and forecast life cycle sustainment requirements of <span class="hlt">IMS</span> facilities. Through historical data analysis, Engineering inputs and Feedback from experienced Station Operators, the PTS currently works towards increasing the level of confidence on these forecasts and sustainment requirements planning. Continued validation, feedback and improvement of source data from scientific community and experienced users is sought and essential in order to ensure limited effect on data availability and optimal costs (human and financial).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060051759&hterms=pcp&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dpcp','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060051759&hterms=pcp&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dpcp"><span>Miniature GC-Minicell Ion Mobility Spectrometer (<span class="hlt">IMS</span>) for In Situ Measurements in Astrobiology Planetary Missions</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Holland, Paul M.; Takeuchi, Norishige</p> <p>2006-01-01</p> <p>Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or ionger mission life for stationary landers/laboratories. The miniCometary Ice and Dust Experiment (miniCIDEX), which combined Gas Chromatography (GC) with helium Ion Mobility Spectrometry (<span class="hlt">IMS</span>), was capable of providing the wide range of analytical information required for Astrobiology missions. The <span class="hlt">IMS</span> used here was based on the PCP model 111 <span class="hlt">IMS</span>. A similar system, the Titan Ice and Dust Experiment (TIDE), was proposed as part of the Titan Orbiter Aerorover Mission (TOAM). Newer GC systems employing Micro Electro- Mechanical System (MEMS) based technology have greatly reduced both the size and resource requirements for space GCs. These smaller GCs, as well as the continuing miniaturization of Astrobiology analytical instruments in general, has highlighted the need for smaller, dry helium <span class="hlt">IMS</span> systems. We describe here the development of a miniature, MEMS GC-<span class="hlt">IMS</span> system (MEMS GC developed by Thorleaf Research Inc.), employing the MiniCell Ion Mobility Spectrometer (<span class="hlt">IMS</span>), from Ion Applications Inc., developed through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA s Small Business Innovative Research (SBIR) Program.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26750519','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26750519"><span>Nanomaterial size distribution analysis via liquid nebulization coupled with ion mobility spectrometry (LN-<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jeon, Seongho; Oberreit, Derek R; Van Schooneveld, Gary; Hogan, Christopher J</p> <p>2016-02-21</p> <p>We apply liquid nebulization (LN) in series with ion mobility spectrometry (<span class="hlt">IMS</span>, using a differential mobility analyzer coupled to a condensation particle counter) to measure the size distribution functions (the number concentration per unit log diameter) of gold nanospheres in the 5-30 nm range, 70 nm × 11.7 nm gold nanorods, and albumin proteins originally in aqueous suspensions. In prior studies, <span class="hlt">IMS</span> measurements have only been carried out for colloidal nanoparticles in this size range using electrosprays for aerosolization, as traditional nebulizers produce supermicrometer droplets which leave residue particles from non-volatile species. Residue particles mask the size distribution of the particles of interest. Uniquely, the LN employed in this study uses both online dilution (with dilution factors of up to 10(4)) with ultra-high purity water and a ball-impactor to remove droplets larger than 500 nm in diameter. This combination enables hydrosol-to-aerosol conversion preserving the size and morphology of particles, and also enables higher non-volatile residue tolerance than electrospray based aerosolization. Through LN-<span class="hlt">IMS</span> measurements we show that the size distribution functions of narrowly distributed but similarly sized particles can be distinguished from one another, which is not possible with Nanoparticle Tracking Analysis in the sub-30 nm size range. Through comparison to electron microscopy measurements, we find that the size distribution functions inferred via LN-<span class="hlt">IMS</span> measurements correspond to the particle sizes coated by surfactants, i.e. as they persist in colloidal suspensions. Finally, we show that the gas phase particle concentrations inferred from <span class="hlt">IMS</span> size distribution functions are functions of only of the liquid phase particle concentration, and are independent of particle size, shape, and chemical composition. Therefore LN-<span class="hlt">IMS</span> enables characterization of the size, yield, and polydispersity of sub-30 nm particles.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060051759&hterms=astrobiology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dastrobiology','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060051759&hterms=astrobiology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dastrobiology"><span>Miniature GC-Minicell Ion Mobility Spectrometer (<span class="hlt">IMS</span>) for In Situ Measurements in Astrobiology Planetary Missions</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Holland, Paul M.; Takeuchi, Norishige</p> <p>2006-01-01</p> <p>Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or ionger mission life for stationary landers/laboratories. The miniCometary Ice and Dust Experiment (miniCIDEX), which combined Gas Chromatography (GC) with helium Ion Mobility Spectrometry (<span class="hlt">IMS</span>), was capable of providing the wide range of analytical information required for Astrobiology missions. The <span class="hlt">IMS</span> used here was based on the PCP model 111 <span class="hlt">IMS</span>. A similar system, the Titan Ice and Dust Experiment (TIDE), was proposed as part of the Titan Orbiter Aerorover Mission (TOAM). Newer GC systems employing Micro Electro- Mechanical System (MEMS) based technology have greatly reduced both the size and resource requirements for space GCs. These smaller GCs, as well as the continuing miniaturization of Astrobiology analytical instruments in general, has highlighted the need for smaller, dry helium <span class="hlt">IMS</span> systems. We describe here the development of a miniature, MEMS GC-<span class="hlt">IMS</span> system (MEMS GC developed by Thorleaf Research Inc.), employing the MiniCell Ion Mobility Spectrometer (<span class="hlt">IMS</span>), from Ion Applications Inc., developed through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA s Small Business Innovative Research (SBIR) Program.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2664073','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2664073"><span>Toxicity and Intraocular Properties of a Novel Long-Acting Anti-Proliferative and Anti-Angiogenic Compound <span class="hlt">IMS</span>2186</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Falkenstein, Iryna A.; Cheng, Lingyun; Wong-Staal, Flossie; Tammewar, Ajay M.; Barron, Erin C.; Silva, Gabriel A.; Li, Qi-Xiang; Yu, Dehua; Hysell, Michelle; Liu, Guohong; Ke, Ning; Macdonald, James E.; Freeman, William R.</p> <p>2009-01-01</p> <p>Purpose To investigate the intraocular properties and toxicity of <span class="hlt">IMS</span>2186, a small molecule developed as an anti-choroidal neovascularization (anti-CNV) drug. Materials and Methods Cellular toxicity and mechanism of action was tested on cell lines in vitro. Intraocular studies used rabbits for drug dissolution as well as toxicity and rats for the treatment study as well as the toxicity confirmation study. Rabbits' eyes were injected with 2.5 mg of <span class="hlt">IMS</span>2186 and observed for 36 weeks. Laser-induced CNV in rats was treated with <span class="hlt">IMS</span>2186, Kenalog, or phosphate-buffered saline (pBS). Fluorescein angiography (FA) and immunohistochemical processing of the globes was performed. Results The anti-proliferative IC50 of <span class="hlt">IMS</span>2186 for human fibroblast cells was 1.0–3.0 μM and 0.3–3.0 μM for human cancer cells; the IC50 of <span class="hlt">IMS</span>2186 to inhibit endothelial tube formation was 0.1–0.3 μM. The IC50 of <span class="hlt">IMS</span>2186 for inhibiting the production of pro-inflammatory cytokines was 0.3–1 μM. The IC50 of <span class="hlt">IMS</span>2186 for inhibiting macrophage migration was 1 μM. These biological properties were not species specific. <span class="hlt">IMS</span>2186 can be formulated as a suspension for long-lasting release and when delivered intraocularly, no intraocular toxicity was observed by slit lamp exam, fundus exam, intraocular pressure measurements, or by electroretinography. FA showed a reduction in the leakage in eyes treated with <span class="hlt">IMS</span>2186 and triamcinolone acetonide; DAPI staining also showed significantly less cellularity in <span class="hlt">IMS</span>2186-treated lesions as compared to PBS (p = 0.0025). Conclusion <span class="hlt">IMS</span>2186 may be a safe intraocular therapeutic agent for intraocular proliferation and angiogenesis. PMID:18600493</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026864','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026864"><span>Application of Ion Mobility Spectrometry (<span class="hlt">IMS</span>) in forensic chemistry and toxicology with focus on biological matrices</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Bernhard, Werner; Keller, Thomas; Regenscheit, Priska</p> <p>1995-01-01</p> <p>The <span class="hlt">IMS</span> (Ion Mobility Spectroscopy) instrument 'Ionscan' takes advantage of the fact that trace quantities of illicit drugs are adsorbed on dust particles on clothes, in cars and on other items of evidence. The dust particles are collected on a membrane filter by a special attachment on a vacuum cleaner. The sample is then directly inserted into the spectrometer and can be analyzed immediately. We show casework applications of a forensic chemistry and toxicology laboratory. One new application of <span class="hlt">IMS</span> in forensic chemistry is the detection of psilocybin in dried mushrooms without any further sample preparation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26074605','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26074605"><span>Power-efficient method for <span class="hlt">IM</span>-DD optical transmission of multiple OFDM signals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Effenberger, Frank; Liu, Xiang</p> <p>2015-05-18</p> <p>We propose a power-efficient method for transmitting multiple frequency-division multiplexed (FDM) orthogonal frequency-division multiplexing (OFDM) signals in intensity-modulation direct-detection (<span class="hlt">IM</span>-DD) optical systems. This method is based on quadratic soft clipping in combination with odd-only channel mapping. We show, both analytically and experimentally, that the proposed approach is capable of improving the power efficiency by about 3 dB as compared to conventional FDM OFDM signals under practical bias conditions, making it a viable solution in applications such as optical fiber-wireless integrated systems where both <span class="hlt">IM</span>-DD optical transmission and OFDM signaling are important.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010cps..book...33F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010cps..book...33F"><span>Innovation <span class="hlt">im</span> Mittelstand am Beispiel Der Senkung Von Mobilitätskosten Durch Schwarmintelligenz"</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Fischer, Hieronymus</p> <p></p> <p>Die zunehmende Vernetzung von Einzelsystemen <span class="hlt">im</span> Fahrzeug wird durch den Einsatz weiterer Kommunikationsverbindungen (CAR2X-Kommunikation) zu einer hierarchischen Struktur führen, die den Austausch von Informationen zwischen einer Vielzahl von verteilten heterogenen Subsystemen auf mobilen und stationären Plattformen ermöglicht. Die primären Ziele einer solchen Vernetzung von Cyber-Physical Systems sind die Bereitstellung neuer Dienste <span class="hlt">im</span> Fahrzeug, die Erhöhung der Verkehrssicherheit sowie die effektive Steuerung der weiter wachsenden Verkehrsströme.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/977770','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/977770"><span>Datamart use for complex data retrieval in an Arc<span class="hlt">IMS</span> application</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Scherma, S.; Bolivar, Stephen L.</p> <p>2004-01-01</p> <p>This paper describes the use of datamarts and data warehousing concepts to expedite retrieval and display of complex attribute data from multi-million record databases. Los Alamos National Laboratory has developed an Internet application (SMART) using Arc<span class="hlt">IMS</span> that relies on datamarts to quickly retrieve attribute data, associated with, but not contained within GIS layers. The volume of data and the complex relationships within the transactional database made data display within Arc<span class="hlt">IMS</span> impractical without the use of datamarts. The technical issues and solutions involved in the development are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28891096','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28891096"><span>N-Phosphine Oxide-Substituted Imidazolylidenes (Pox<span class="hlt">Ims</span>): Multifunctional Multipurpose Carbenes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hazra, Sunit; Hoshimoto, Yoichi; Ogoshi, Sensuke</p> <p>2017-09-10</p> <p>This article discusses the concept of N-heterocyclic carbenes (NHCs) equipped with more than one functional moiety, which allows using these NHCs for multiple purposes. A pioneering example for such NHCs is N-phosphine oxide-substituted imidazolylidenes (Pox<span class="hlt">Ims</span>), and their synthesis and strategic use are highlighted. The utility of Pox<span class="hlt">Ims</span> by far exceeds the conventional use as multidentate ligands for metal complexes on account of the synergetic functions of the carbene and the N-phosphine oxide group(s). © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-10-13/pdf/2011-26426.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-10-13/pdf/2011-26426.pdf"><span>76 FR 63659 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; <span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-10-13</p> <p>... National Cooperative Research and Production Act of 1993; <span class="hlt">IMS</span> Global Learning Consortium, Inc. Notice is... and Production Act of 1993, 15 U.S.C. 4301 et seq. (``the Act''), INS Global Learning Consortium, Inc... remains open, and <span class="hlt">IMS</span> Global Learning Consortium, Inc. intends to file additional written...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-04-05/pdf/2011-7936.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-04-05/pdf/2011-7936.pdf"><span>76 FR 18797 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-04-05</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on March 3, 2011, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the Attorney... research project remains open, and <span class="hlt">IMS</span> Global Learning Consortium, Inc. intends to file additional...</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_10 --> <div id="page_11" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="201"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2013-06-21/pdf/2013-14777.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2013-06-21/pdf/2013-14777.pdf"><span>78 FR 37571 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2013-06-21</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on May 30, 2013, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. (``<span class="hlt">IMS</span> Global'') has ] filed written notifications simultaneously...., New York, NY; and LearningMate Solutions, Inc., New York, NY, have been added as parties to...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-12-21/pdf/2011-32699.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-12-21/pdf/2011-32699.pdf"><span>76 FR 79217 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-12-21</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on November 28, 2011, pursuant to section 6... Act''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the... research project. Membership in this group research project remains open, and <span class="hlt">IMS</span> Global...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-06-13/pdf/2011-14514.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-06-13/pdf/2011-14514.pdf"><span>76 FR 34252 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; <span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-06-13</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on May 9, 2011, pursuant to Section 6(a) of...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the Attorney... remains open, and <span class="hlt">IMS</span> Global Learning Consortium, Inc. intends to file additional written...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-08-18/pdf/2010-20220.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-08-18/pdf/2010-20220.pdf"><span>75 FR 51114 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-08-18</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on July 13, 2010, pursuant to Section 6(a...''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the Attorney.... Membership in this group research project remains open, and <span class="hlt">IMS</span> Global Learning Consortium, Inc. intends...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2012-03-02/pdf/2012-5185.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2012-03-02/pdf/2012-5185.pdf"><span>77 FR 12881 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2012-03-02</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on February 6, 2012, pursuant to Section 6... Act''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the... research project. Membership in this group research project remains open, and <span class="hlt">IMS</span> Global...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol4/pdf/CFR-2011-title40-vol4-sec52-2348.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol4/pdf/CFR-2011-title40-vol4-sec52-2348.pdf"><span>40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-07-01</p> <p>... 40 Protection of Environment 4 2011-07-01 2011-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (<span class="hlt">I/M</span>) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol4/pdf/CFR-2010-title40-vol4-sec52-2348.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol4/pdf/CFR-2010-title40-vol4-sec52-2348.pdf"><span>40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-07-01</p> <p>... 40 Protection of Environment 4 2010-07-01 2010-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (<span class="hlt">I/M</span>) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5113207','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5113207"><span>Evolution of tRNAPhe:<span class="hlt">im</span>G2 methyltransferases involved in the biosynthesis of wyosine derivatives in Archaea</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Urbonavičius, Jaunius; Rutkienė, Rasa; Lopato, Anželika; Tauraitė, Daiva; Stankevičiūtė, Jonita; Aučynaitė, Agota; Kaliniene, Laura; van Tilbeurgh, Herman; Meškys, Rolandas</p> <p>2016-01-01</p> <p>Tricyclic wyosine derivatives are found at position 37 of eukaryotic and archaeal tRNAPhe. In Archaea, the intermediate <span class="hlt">im</span>G-14 is targeted by three different enzymes that catalyze the formation of yW-86, <span class="hlt">im</span>G, and <span class="hlt">im</span>G2. We have suggested previously that a peculiar methyltransferase (aTrm5a/Taw22) likely catalyzes two distinct reactions: N1-methylation of guanosine to yield m1G; and C7-methylation of <span class="hlt">im</span>G-14 to yield <span class="hlt">im</span>G2. Here we show that the recombinant aTrm5a/Taw22-like enzymes from both Pyrococcus abyssi and Nanoarchaeum equitans indeed possess such dual specificity. We also show that substitutions of individual conservative amino acids of P. abyssi Taw22 (P260N, E173A, and R174A) have a differential effect on the formation of m1G/<span class="hlt">im</span>G2, while replacement of R134, F165, E213, and P262 with alanine abolishes the formation of both derivatives of G37. We further demonstrate that aTrm5a-type enzyme SSO2439 from Sulfolobus solfataricus, which has no N1-methyltransferase activity, exhibits C7-methyltransferase activity, thereby producing <span class="hlt">im</span>G2 from <span class="hlt">im</span>G-14. We thus suggest renaming such aTrm5a methyltransferases as Taw21 to distinguish between monofunctional and bifunctional aTrm5a enzymes. PMID:27852927</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15061610','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15061610"><span>Development of the <span class="hlt">IM</span>147: an alternative inspection/maintenance mass-emission transient test to address vehicle preconditioning concerns.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Joy, Richard W; Heirigs, Philip L; Torgerson, Garrett D; St Denis, Michael; Austin, Thomas C; Gordon, Jay; Tefft, Bob; Lindner, Jim</p> <p>2004-03-01</p> <p>A series of studies was performed to develop an alternative to the U.S. Environmental Protection Agency's gold standard <span class="hlt">IM</span>240 mass-based emission test. The new <span class="hlt">IM</span>147 test was based on the second phase of the <span class="hlt">IM</span>240 that consists of 147 sec of transient vehicle operation. Paired <span class="hlt">IM</span>240/<span class="hlt">IM</span>147 tests were conducted on vehicles ranging from 1981 to 1996 to determine <span class="hlt">IM</span>147 cutpoints and excess emissions were identified. Additionally, an optimized test procedure was developed that combined possible triplicate <span class="hlt">IM</span>147s with improved drive trace quality control, fast-pass, and retest methods. The optimized procedure was found to provide improved vehicle preconditioning with a relatively minor decrease in excess emissions identification. Resulting identification rates ranged from 96 to 100% for hydrocarbons (HC), 93-100% for CO, and 93-100% for NOx, depending on cutpoint selection, while false failures caused by lack of vehicle preconditioning were reduced to essentially zero. Significant vehicle throughput improvements were achieved through the development of software algorithms involving modal fast-pass and retest procedures. Modal drive trace variation limits also were developed to improve test accuracy. The combination of the algorithms reduced average <span class="hlt">IM</span>147 test times by nearly 60%.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=graphical+AND+user+AND+interface&pg=5&id=EJ836701','ERIC'); return false;" href="http://eric.ed.gov/?q=graphical+AND+user+AND+interface&pg=5&id=EJ836701"><span>Usability of a Runtime Environment for the Use of <span class="hlt">IMS</span> Learning Design in Mixed Mode Higher Education</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Klebl, Michael</p> <p>2006-01-01</p> <p>Starting from the first public draft of <span class="hlt">IMS</span> Learning Design in November 2002, a research project at the Catholic University Eichstaett-Ingolstadt in Germany was dedicated to the conceptual examination and empirical review of <span class="hlt">IMS</span> Learning Design Level A. A prototypical runtime environment called "lab005" was developed. It was built based…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23953458','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23953458"><span>Determination of chlorophenols in water by headspace solid phase microextraction ion mobility spectrometry (HS-SPME-<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Holopainen, Sanna; Luukkonen, Ville; Nousiainen, Marjaana; Sillanpää, Mika</p> <p>2013-09-30</p> <p>Chlorophenols (CPs) as persistent toxic compounds are of worldwide environmental concern. Usage of chlorinated phenols, especially pentachlorophenol (PCP), has been restricted or widely banned in many countries due to their possible adverse health effects even at low concentrations. Ion mobility spectrometry (<span class="hlt">IMS</span>) has received increasing interest in environmental applications due to its unique characteristics, such as portability and speed of analysis. A range of sample introduction methods combined with <span class="hlt">IMS</span> enable analysis from different environmental matrices. This study utilised headspace solid phase microextraction <span class="hlt">IMS</span> (HS-SPME-<span class="hlt">IMS</span>) in the determination of CPs from water samples. The extraction conditions were examined and the method was applied to real water samples. The developed method is suitable to detect CPs at milligram per liter level in water. Based on the results, SPME-<span class="hlt">IMS</span> setup is feasible as an early warning system for water monitoring of pollutants present in drinking or surface water in case of environmental accidents or leakages.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Messenger&pg=5&id=ED528739','ERIC'); return false;" href="http://eric.ed.gov/?q=Messenger&pg=5&id=ED528739"><span>W8...b4 <span class="hlt">IM</span>, how did u rite??! Digital Writing in the Composition Classroom</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Partridge, Bryan</p> <p>2011-01-01</p> <p>From word processing computers, to mobile telephones, to the advent of the Internet, and finally to online communication venues like Instant Messenger (<span class="hlt">IM</span>), the past four decades have brought an increasing prevalence of technology into our culture that is altering the English language. While decried by parents and lamented by teachers, these…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=Particle+AND+meaning&pg=3&id=ED549334','ERIC'); return false;" href="https://eric.ed.gov/?q=Particle+AND+meaning&pg=3&id=ED549334"><span>The Role of Ki '<span class="hlt">Im</span> in Orchestrating Contrastive Focus in Biblical Hebrew</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Park, Grace Jeongyeon</p> <p>2011-01-01</p> <p>The so-called compound use of ki '<span class="hlt">im</span> has been interpreted mainly either with exceptive ("except" or "unless") or adversative meaning ("but" or "rather"), although it has sometimes also been interpreted in other ways such as "only" or "surely". These various meanings have been applied…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.ars.usda.gov/research/publications/publication/?seqNo115=279761','TEKTRAN'); return false;" href="http://www.ars.usda.gov/research/publications/publication/?seqNo115=279761"><span><span class="hlt">im</span>DEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel</span></a></p> <p><a target="_blank" href="https://www.ars.usda.gov/research/publications/find-a-publication/">USDA-ARS?s Scientific Manuscript database</a></p> <p></p> <p></p> <p>Interactive modules for data exploration and visualization (<span class="hlt">im</span>DEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data sets with a user-friendly interface. Individual modules were designed to provide toolsets to enable interactive ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28971826','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28971826"><span>The implementation of the Plan Esperanza and response to the <span class="hlt">im</span>PACT Review.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vidaurre, Tatiana; Santos, Carlos; Gómez, Henry; Sarria, Gustavo; Amorin, Edgar; López, Marga; Regalado, Roxana; Manrique, Javier; Tarco, Duniska; Ayestas, Carlos; Calderón, Mónica; Mas, Luis; Neciosup, Silvia; Salazar, Miriam; Chávez, Juan Carlos; Ubillus, Milward; Limache, Abel; Ubillus, José Carlos; Navarro, Jeannie; Sarwal, Kavita; Sutcliffe, Simon; Gutiérrez-Aguado, Alfonso; Silva, Marianela; Mena, Amalia; Guillén, María Eugenia; Castañeda, Carlos; Abugattas, Julio</p> <p>2017-10-01</p> <p>Following the implementation of the National Cancer Prevention and Control Results-based Budget Programme (PpR Cancer-024) in 2011, the Peruvian Government approved the Plan Esperanza-a population-based national cancer control plan-in 2012. Legislation that ensured full government-supported funding for people who were otherwise unable to access or afford care and treatment accompanied the Plan. In 2013, the Ministry of Health requested an integrated mission of the Programme of Action for Cancer Therapy (<span class="hlt">im</span>PACT) report to strengthen cancer control in Peru. The <span class="hlt">im</span>PACT Review, which was executed in 2014, assessed Peru's achievements in cancer control, and areas for improvement, including cancer control planning, further development of population-based cancer registration, increased prevention, early diagnosis, treatment and palliative care, and the engagement and participation of civil society in the health-care system. This Series paper gives a brief history of the development of the Plan Esperanza, describes the innovative funding model that supports it, and summarises how funds are disseminated on the basis of disease, geography, and demographics. An overview of the <span class="hlt">im</span>PACT Review, and the government's response in the context of the Plan Esperanza, is provided. The development and execution of the Plan Esperanza and the execution of and response to the <span class="hlt">im</span>PACT Review demonstrates the Peruvian Government's commitment to fighting cancer across the country, including in remote and urban areas. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=web+AND+service&id=EJ1053110','ERIC'); return false;" href="https://eric.ed.gov/?q=web+AND+service&id=EJ1053110"><span>A Service Oriented Web Application for Learner Knowledge Representation, Management and Sharing Conforming to <span class="hlt">IMS</span> LIP</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lazarinis, Fotis</p> <p>2014-01-01</p> <p>iLM is a Web based application for representation, management and sharing of <span class="hlt">IMS</span> LIP conformant user profiles. The tool is developed using a service oriented architecture with emphasis on the easy data sharing. Data elicitation from user profiles is based on the utilization of XQuery scripts and sharing with other applications is achieved through…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=evolution+AND+eye&pg=2&id=ED528739','ERIC'); return false;" href="https://eric.ed.gov/?q=evolution+AND+eye&pg=2&id=ED528739"><span>W8...b4 <span class="hlt">IM</span>, how did u rite??! Digital Writing in the Composition Classroom</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Partridge, Bryan</p> <p>2011-01-01</p> <p>From word processing computers, to mobile telephones, to the advent of the Internet, and finally to online communication venues like Instant Messenger (<span class="hlt">IM</span>), the past four decades have brought an increasing prevalence of technology into our culture that is altering the English language. While decried by parents and lamented by teachers, these…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=jacobson&pg=2&id=ED532952','ERIC'); return false;" href="https://eric.ed.gov/?q=jacobson&pg=2&id=ED532952"><span>No More "<span class="hlt">I'm</span> Done!": Fostering Independent Writers in the Primary Grades</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Jacobson, Jennifer</p> <p>2010-01-01</p> <p>Yes! Primary students can grow into being independent writers! Disregarding the false notion that writing instruction in the primary grades needs to be mostly teacher directed, Jennifer Jacobson shows teachers how to develop a primary writing workshop that helps nurture independent, engaged writers. "No More <span class="hlt">I'm</span> Done!" demonstrates how to create a…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=soa&id=EJ1007598','ERIC'); return false;" href="http://eric.ed.gov/?q=soa&id=EJ1007598"><span>Investigating Perfect Timesharing: The Relationship between <span class="hlt">IM</span>-Compatible Tasks and Dual-Task Performance</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Halvorson, Kimberly M.; Ebner, Herschel; Hazeltine, Eliot</p> <p>2013-01-01</p> <p>Why are dual-task costs reduced with ideomotor (<span class="hlt">IM</span>) compatible tasks (Greenwald & Shulman, 1973; Lien, Proctor & Allen, 2002)? In the present experiments, we first examine three different measures of single-task performance (pure single-task blocks, mixed blocks, and long stimulus onset asynchrony [SOA] trials in dual-task blocks) and two…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=action+AND+potential&pg=7&id=EJ1088357','ERIC'); return false;" href="https://eric.ed.gov/?q=action+AND+potential&pg=7&id=EJ1088357"><span>"<span class="hlt">I'm</span> Sorry + Naming the Offense": A Format for Apologizing</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cirillo, Letizia; Colón de Carvajal, Isabel; Ticca, Anna Claudia</p> <p>2016-01-01</p> <p>The present article focuses on "<span class="hlt">I'm</span> sorry + naming the offense"-formatted apologies occurring in phone calls in English. Apologies of this kind "emerge" and are oriented to as relevant actions when addressing an apologizable that is not the main business in ongoing talk. The sequential analysis of apologies and responses to…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_11 --> <div id="page_12" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="221"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=chemistry+AND+principle+AND+practice&pg=7&id=EJ740459','ERIC'); return false;" href="https://eric.ed.gov/?q=chemistry+AND+principle+AND+practice&pg=7&id=EJ740459"><span>"Chemie <span class="hlt">im</span> Kontext": A Symbiotic Implementation of a Context-Based Teaching and Learning Approach</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Parchmann, Ilka; Grasel, Cornelia; Baer, Anja; Nentwig, Peter; Demuth, Reinhard; Ralle, Bernd</p> <p>2006-01-01</p> <p>"Chemie <span class="hlt">im</span> Kontext" (ChiK) is a project that aims at the improvement of chemistry teaching at secondary school in Germany. Based on a framework that was derived from theories and empirical data on the teaching and learning of science, science education researchers and teachers work together on learning communities to transform this…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=making+AND+study+AND+materials&pg=4&id=EJ1026047','ERIC'); return false;" href="https://eric.ed.gov/?q=making+AND+study+AND+materials&pg=4&id=EJ1026047"><span>The (<span class="hlt">Im</span>)Materiality of Literacy: The Significance of Subjectivity to New Literacies Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Burnett, Cathy; Merchant, Guy; Pahl, Kate; Rowsell, Jennifer</p> <p>2014-01-01</p> <p>This article deconstructs the online and offline experience to show its complexities and idiosyncratic nature. It proposes a theoretical framework designed to conceptualise aspects of meaning-making across on- and offline contexts. In arguing for the "(<span class="hlt">im</span>)materiality" of literacy, it makes four propositions which highlight the complex…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=allen&pg=5&id=EJ1007598','ERIC'); return false;" href="https://eric.ed.gov/?q=allen&pg=5&id=EJ1007598"><span>Investigating Perfect Timesharing: The Relationship between <span class="hlt">IM</span>-Compatible Tasks and Dual-Task Performance</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Halvorson, Kimberly M.; Ebner, Herschel; Hazeltine, Eliot</p> <p>2013-01-01</p> <p>Why are dual-task costs reduced with ideomotor (<span class="hlt">IM</span>) compatible tasks (Greenwald & Shulman, 1973; Lien, Proctor & Allen, 2002)? In the present experiments, we first examine three different measures of single-task performance (pure single-task blocks, mixed blocks, and long stimulus onset asynchrony [SOA] trials in dual-task blocks) and two…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=%22life+cycle%22+AND+paper&pg=3&id=EJ918741','ERIC'); return false;" href="https://eric.ed.gov/?q=%22life+cycle%22+AND+paper&pg=3&id=EJ918741"><span>Generic Service Integration in Adaptive Learning Experiences Using <span class="hlt">IMS</span> Learning Design</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>de-la-Fuente-Valentin, Luis; Pardo, Abelardo; Kloos, Carlos Delgado</p> <p>2011-01-01</p> <p><span class="hlt">IMS</span> Learning Design is a specification to capture the orchestration taking place in a learning scenario. This paper presents an extension called Generic Service Integration. This paradigm allows a bidirectional communication between the course engine in charge of the orchestration and conventional Web 2.0 tools. This communication allows the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=solidarity&pg=5&id=EJ1088357','ERIC'); return false;" href="http://eric.ed.gov/?q=solidarity&pg=5&id=EJ1088357"><span>"<span class="hlt">I'm</span> Sorry + Naming the Offense": A Format for Apologizing</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cirillo, Letizia; Colón de Carvajal, Isabel; Ticca, Anna Claudia</p> <p>2016-01-01</p> <p>The present article focuses on "<span class="hlt">I'm</span> sorry + naming the offense"-formatted apologies occurring in phone calls in English. Apologies of this kind "emerge" and are oriented to as relevant actions when addressing an apologizable that is not the main business in ongoing talk. The sequential analysis of apologies and responses to…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Baroque&id=EJ1026047','ERIC'); return false;" href="http://eric.ed.gov/?q=Baroque&id=EJ1026047"><span>The (<span class="hlt">Im</span>)Materiality of Literacy: The Significance of Subjectivity to New Literacies Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Burnett, Cathy; Merchant, Guy; Pahl, Kate; Rowsell, Jennifer</p> <p>2014-01-01</p> <p>This article deconstructs the online and offline experience to show its complexities and idiosyncratic nature. It proposes a theoretical framework designed to conceptualise aspects of meaning-making across on- and offline contexts. In arguing for the "(<span class="hlt">im</span>)materiality" of literacy, it makes four propositions which highlight the complex…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19760052768&hterms=Aries&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3DAries','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19760052768&hterms=Aries&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3DAries"><span>The Aries Program with emphasis on the International Magnetospherics Studies /<span class="hlt">IMS</span>/-Porcupine Project</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Honecker, H. J.</p> <p>1976-01-01</p> <p>This paper will discuss the present state of the development of the Aries Sounding Rocket System with particular emphasis on the configuration and subsystems required to support the <span class="hlt">IMS</span> Program. A brief history of the development program will be presented. The results of the first five flights, three successes and two failures, will be presented and the observed performance compared to theoretical performance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=role+AND+distribution&pg=2&id=EJ860434','ERIC'); return false;" href="http://eric.ed.gov/?q=role+AND+distribution&pg=2&id=EJ860434"><span>InstanceCollage: A Tool for the Particularization of Collaborative <span class="hlt">IMS</span>-LD Scripts</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Villasclaras-Fernandez, Eloy D.; Hernandez-Gonzalo, Julio A.; Hernandez-Leo, Davinia; Asensio-Perez, Juan I.; Dimitriadis, Yannis; Martinez-Mones, Alejandra</p> <p>2009-01-01</p> <p>Current research work in e-learning and more specifically in the field of CSCL (Computer Supported Collaborative Learning) deals with design of collaborative activities, according to computer-interpretable specifications, such as <span class="hlt">IMS</span> Learning Design, and their posterior enactment using LMSs (Learning Management Systems). A script that describes…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=eloy+AND+fernandez&id=EJ860434','ERIC'); return false;" href="https://eric.ed.gov/?q=eloy+AND+fernandez&id=EJ860434"><span>InstanceCollage: A Tool for the Particularization of Collaborative <span class="hlt">IMS</span>-LD Scripts</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Villasclaras-Fernandez, Eloy D.; Hernandez-Gonzalo, Julio A.; Hernandez-Leo, Davinia; Asensio-Perez, Juan I.; Dimitriadis, Yannis; Martinez-Mones, Alejandra</p> <p>2009-01-01</p> <p>Current research work in e-learning and more specifically in the field of CSCL (Computer Supported Collaborative Learning) deals with design of collaborative activities, according to computer-interpretable specifications, such as <span class="hlt">IMS</span> Learning Design, and their posterior enactment using LMSs (Learning Management Systems). A script that describes…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19760052768&hterms=Porcupines&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DPorcupines','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19760052768&hterms=Porcupines&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DPorcupines"><span>The Aries Program with emphasis on the International Magnetospherics Studies /<span class="hlt">IMS</span>/-Porcupine Project</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Honecker, H. J.</p> <p>1976-01-01</p> <p>This paper will discuss the present state of the development of the Aries Sounding Rocket System with particular emphasis on the configuration and subsystems required to support the <span class="hlt">IMS</span> Program. A brief history of the development program will be presented. The results of the first five flights, three successes and two failures, will be presented and the observed performance compared to theoretical performance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=user+AND+profile&id=EJ1053110','ERIC'); return false;" href="http://eric.ed.gov/?q=user+AND+profile&id=EJ1053110"><span>A Service Oriented Web Application for Learner Knowledge Representation, Management and Sharing Conforming to <span class="hlt">IMS</span> LIP</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lazarinis, Fotis</p> <p>2014-01-01</p> <p>iLM is a Web based application for representation, management and sharing of <span class="hlt">IMS</span> LIP conformant user profiles. The tool is developed using a service oriented architecture with emphasis on the easy data sharing. Data elicitation from user profiles is based on the utilization of XQuery scripts and sharing with other applications is achieved through…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=%22expert+system%22&pg=4&id=EJ836702','ERIC'); return false;" href="https://eric.ed.gov/?q=%22expert+system%22&pg=4&id=EJ836702"><span>Knowledge Base for Automatic Generation of Online <span class="hlt">IMS</span> LD Compliant Course Structures</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Pacurar, Ecaterina Giacomini; Trigano, Philippe; Alupoaie, Sorin</p> <p>2006-01-01</p> <p>Our article presents a pedagogical scenarios-based web application that allows the automatic generation and development of pedagogical websites. These pedagogical scenarios are represented in the <span class="hlt">IMS</span> Learning Design standard. Our application is a web portal helping teachers to dynamically generate web course structures, to edit pedagogical content…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=fault&pg=4&id=EJ1088396','ERIC'); return false;" href="http://eric.ed.gov/?q=fault&pg=4&id=EJ1088396"><span><span class="hlt">I'm</span> Sorry "About That": Apologies, Indexicals, and (Unnamed) Offenses</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Margutti, Piera; Traverso, Véronique; Pugliese, Rosa</p> <p>2016-01-01</p> <p>We investigate an apology format, "<span class="hlt">I'm</span> sorry about it/that," where indexical terms (pronouns) refer to the offense rather than naming it. We identified two subsets in our collection of indexical apologies. In one, indexicals are subsequent either to the offense formulation or to an apology-relevant event; in the second, indexicals are…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110016110','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110016110"><span>Out-Life Characteristics of <span class="hlt">IM</span>7/977-3 Composites</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Miller, Sandi G.; Sutter, James K.; Hou, Tan-Hung; Scheiman, Daniel A.; Martin, Richard E.; Maryanski, Michael; Schlea, Michelle; Gardner, John M.; Schiferl, Zack R.</p> <p>2010-01-01</p> <p>The capability to manufacture large structures leads to weight savings and reduced risk relative to joining smaller components. However, manufacture of increasingly large composite components is pushing the out-time limits of epoxy/ carbon fiber prepreg. <span class="hlt">IM</span>7/977-3 is an autoclave processable prepreg material, commonly used in aerospace structures. The out-time limit is reported as 30 days by the manufacturer. The purpose of this work was to evaluate the material processability and composite properties of 977-3 resin and <span class="hlt">IM</span>7/977-3 prepreg that had been aged at room temperature for up to 60 days. The effects of room temperature aging on the thermal and visco-elastic properties of the materials were investigated. Neat resin was evaluated by differential scanning calorimetry to characterize thermal properties and change in activation energy of cure. Neat resin was also evaluated by rheometry to characterize its processability in composite fabrication. <span class="hlt">IM</span>7/977-3 prepreg was evaluated by dynamic mechanical analysis to characterize the curing behavior. Prepreg tack was also evaluated over 60 days. The overall test results suggested that <span class="hlt">IM</span>7/977-3 was a robust material that offered quality laminates throughout this aging process when processed by autoclave.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=scientist&pg=4&id=EJ991267','ERIC'); return false;" href="http://eric.ed.gov/?q=scientist&pg=4&id=EJ991267"><span><span class="hlt">I'm</span> a Scientist, Get Me out of Here! (Australia)</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Teaching Science, 2012</p> <p>2012-01-01</p> <p>The May event of <span class="hlt">I'm</span> a Scientist, Get Me Out of Here! harnessed fifteen scientists in three general zones, engaging almost 800 students from twenty two schools across the country, generating 624 answered questions, 406 comments and fifty three live-chat sessions. (Contains 4 photos.)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=get&pg=7&id=EJ991267','ERIC'); return false;" href="https://eric.ed.gov/?q=get&pg=7&id=EJ991267"><span><span class="hlt">I'm</span> a Scientist, Get Me out of Here! (Australia)</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Teaching Science, 2012</p> <p>2012-01-01</p> <p>The May event of <span class="hlt">I'm</span> a Scientist, Get Me Out of Here! harnessed fifteen scientists in three general zones, engaging almost 800 students from twenty two schools across the country, generating 624 answered questions, 406 comments and fifty three live-chat sessions. (Contains 4 photos.)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=engine&pg=7&id=EJ918741','ERIC'); return false;" href="http://eric.ed.gov/?q=engine&pg=7&id=EJ918741"><span>Generic Service Integration in Adaptive Learning Experiences Using <span class="hlt">IMS</span> Learning Design</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>de-la-Fuente-Valentin, Luis; Pardo, Abelardo; Kloos, Carlos Delgado</p> <p>2011-01-01</p> <p><span class="hlt">IMS</span> Learning Design is a specification to capture the orchestration taking place in a learning scenario. This paper presents an extension called Generic Service Integration. This paradigm allows a bidirectional communication between the course engine in charge of the orchestration and conventional Web 2.0 tools. This communication allows the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=chemie&id=EJ740459','ERIC'); return false;" href="http://eric.ed.gov/?q=chemie&id=EJ740459"><span>"Chemie <span class="hlt">im</span> Kontext": A Symbiotic Implementation of a Context-Based Teaching and Learning Approach</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Parchmann, Ilka; Grasel, Cornelia; Baer, Anja; Nentwig, Peter; Demuth, Reinhard; Ralle, Bernd</p> <p>2006-01-01</p> <p>"Chemie <span class="hlt">im</span> Kontext" (ChiK) is a project that aims at the improvement of chemistry teaching at secondary school in Germany. Based on a framework that was derived from theories and empirical data on the teaching and learning of science, science education researchers and teachers work together on learning communities to transform this…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=jess+AND+expert+AND+system&id=EJ836702','ERIC'); return false;" href="http://eric.ed.gov/?q=jess+AND+expert+AND+system&id=EJ836702"><span>Knowledge Base for Automatic Generation of Online <span class="hlt">IMS</span> LD Compliant Course Structures</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Pacurar, Ecaterina Giacomini; Trigano, Philippe; Alupoaie, Sorin</p> <p>2006-01-01</p> <p>Our article presents a pedagogical scenarios-based web application that allows the automatic generation and development of pedagogical websites. These pedagogical scenarios are represented in the <span class="hlt">IMS</span> Learning Design standard. Our application is a web portal helping teachers to dynamically generate web course structures, to edit pedagogical content…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Independence+AND+Day&pg=5&id=ED532952','ERIC'); return false;" href="http://eric.ed.gov/?q=Independence+AND+Day&pg=5&id=ED532952"><span>No More "<span class="hlt">I'm</span> Done!": Fostering Independent Writers in the Primary Grades</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Jacobson, Jennifer</p> <p>2010-01-01</p> <p>Yes! Primary students can grow into being independent writers! Disregarding the false notion that writing instruction in the primary grades needs to be mostly teacher directed, Jennifer Jacobson shows teachers how to develop a primary writing workshop that helps nurture independent, engaged writers. "No More <span class="hlt">I'm</span> Done!" demonstrates how to create a…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_12 --> <div id="page_13" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="241"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Neuroscience+AND+right&pg=7&id=ED415031','ERIC'); return false;" href="http://eric.ed.gov/?q=Neuroscience+AND+right&pg=7&id=ED415031"><span><span class="hlt">I'm</span> "Only" Bleeding: Education as the Practice of Violence against Children. Counterpoints Volume 10.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Block, Alan A.</p> <p></p> <p>This book explores the construction of the idea of the child as a product of adult needs and school as a place where children may be confined until they are considered socially useful. Drawing parallels with folk singer Bob Dylan's song, "It's All Right, Ma, <span class="hlt">I'm</span> Only Bleeding," the book argues that the United States' educational system practices a…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..1411204M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..1411204M"><span>Engineering and development projects for the sustainment and enhancement of the <span class="hlt">IMS</span> infrasound network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Marty, J.; Martysevich, P.; Kramer, A.; Haralabus, G.</p> <p>2012-04-01</p> <p>The Provisional Technical Secretariat (PTS) of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) has a continuous interest in enhancing its capability in infrasound source localization and characterization. This capability is based on the processing of data recorded by the infrasound network of the International Monitoring System (<span class="hlt">IMS</span>). This infrasound network consists of sixty stations, among which forty-five are already certified and continuously transmit data to the International Data Center (IDC) in Vienna, Austria. Each infrasound station is composed of an array of infrasound sensors capable of measuring micro-pressure changes produced at ground level by infrasonic waves. It is the responsibility of the Engineering and Development Section of the <span class="hlt">IMS</span> Division to ensure the highest quality for <span class="hlt">IMS</span> infrasound data. This includes the design of robust and reliable infrasound stations, the use of accurate and calibrated infrasound measuring chains, the installation of efficient wind noise reduction systems and the implementation of quality-control tools. The purpose of this paper is to present ongoing PTS infrasound engineering and development projects related to the testing and validation of wind noise reduction system models, the implementation of infrasound data QC tools, the definition of guidelines for the design of <span class="hlt">IMS</span> power supply systems and the development of a portable infrasound calibrator and of field kits for site survey and certification.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002PhDT.......175W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002PhDT.......175W"><span>Amplituden der Kernphasen <span class="hlt">im</span> Bereich der Kaustik B und Untersuchung der Struktur der Übergangszone zum inneren Erdkern mit spektralen Amplituden der diffraktierten Phase PKP(BC)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wolf, Michael D. C.</p> <p>2002-04-01</p> <p>ücksichtigt zu werden, da die kumulierte Amplituden-Entfernungskurve anhand der Lage des Maximums auf der Entfernungsachse ausgewertet wird. Folglich wird darauf verzichtet, ein alternatives Q-Modell zu entwickeln. Hinsichtlich der Lage des Kaustikmaximums lassen sich die untersuchten Erdmodelle in zwei Kategorien einteilen. Eine Gruppe besteht aus den Modellen IASP91 und 1066B, deren Maxima bei 144.6 ° und 144.7 ° liegen. Zur zweiten Gruppe von Modellen zählen AK135, PREM und SP6 mit den Maxima bei 145.1 ° und 145.2 ° (SP6). Die gemessene Amplitudenkurve hat <span class="hlt">ihr</span> Maximum bei 145 °. Alle Entfernungsangaben beziehen sich auf eine Herdtiefe von 200 km. Die Kaustikentfernung für einen Oberflächenherd ist jeweils um 0.454 ° gröer als die angegeben Werte. Damit liegen die Maxima der Modelle AK135 und PREM nur 0.1 ° neben dem der gemessenen kumulierten Amplitudenkurve. Daher wird auf die Erstellung eines eigenen Modells verzichtet, da dieses eine unwesentlich verbesserte Amplitudenkurve aufweisen würde. Das Ergebnis der Untersuchung ist die Erstellung einer gemessenen kumulierten Amplituden-Entfernungskurve für die Kaustik B. Die Kurve legt die Position der Kaustik B für kurzperiodische Daten auf ± 0.15 ° fest und bestimmt damit, welche Erdmodelle für die Beschreibung der Amplituden <span class="hlt">im</span> Entfernungsbereich der Kaustik B besonders geeignet sind. Die Erdmodelle AK135 und PREM, ergänzt durch ein einheitliches Q-Modell, geben den Verlauf der Amplituden am besten wieder. Da die Amplitudenkurven beider Modelle nahe beieinander liegen, sind sie als gleichwertig zu bezeichnen. <span class="hlt">Im</span> zweiten Teil der Arbeit wird die Struktur der Übergangszone in den inneren Erdkern anhand des spektralen Abklingens der Phase PKP(BC)diff am Punkt C der Laufzeitkurve untersucht. Der physikalische Proze der Beugung ist für die starke Abnahme der Amplituden dieser Phase verantwortlich. Die Diffraktion beeinflut das Abklingverhalten verschiedener Frequenzanteile des seismischen Signals auf</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28296294','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28296294"><span>Electrocardiogram-gated coronary CT angiography dose estimates using <span class="hlt">Im</span>PACT.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kobayashi, Masanao; Asada, Yasuki; Matsubara, Kosuke; Suzuki, Shouichi; Koshida, Kichiro; Matsunaga, Yuta; Haba, Tomonobu; Kawaguchi, Ai; Toyama, Hiroshi; Kato, Ryoichi</p> <p>2016-07-01</p> <p>The primary study objective was to assess radiation doses using a modified form of the Imaging Performance Assessment of Computed Tomography (CT) scanner (<span class="hlt">Im</span>PACT) patient dosimetry for cardiac applications on an Aquilion ONE ViSION Edition scanner, including the Ca score, target computed tomography angiography (CTA), prospective CTA, continuous CTA/cardiac function analysis (CFA), and CTA/CFA modulation. Accordingly, we clarified the CT dose index (CTDI) to determine the relationship between heart rate (HR) and X-ray exposure. As a secondary objective, we compared radiation doses using modified <span class="hlt">Im</span>PACT, a whole-body dosimetry phantom study, and the k-factor method to verify the validity of the dose results obtained with modified <span class="hlt">Im</span>PACT. The effective dose determined for the reference person (4.66 mSv at 60 beats per minute (bpm) and 33.43 mSv at 90 bpm) were approximately 10% less than those determined for the phantom study (5.28 mSv and 36.68 mSv). The effective doses according to the k-factor (0.014 mSv·mGy-1·cm-1; 2.57 mSv and 17.10 mSv) were significantly lower than those obtained with the other two methods. In the present study, we have shown that <span class="hlt">Im</span>PACT, when modified for cardiac applications, can assess both absorbed and effective doses. The results of our dose comparison indicate that modified <span class="hlt">Im</span>PACT dose assessment is a promising and practical method for evaluating coronary CTA. PACS number(s): 87.57.Q-, 87.59.Dj, 87.57.uq. © 2016 The Authors.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27455500','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27455500"><span>Electrocardiogram-gated coronary CT angiography dose estimates using <span class="hlt">Im</span>PACT.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kobayashi, Masanao; Asada, Yasuki; Matsubara, Kosuke; Suzuki, Shouichi; Koshida, Kichiro; Matsunaga, Yuta; Haba, Tomonobu; Kawaguchi, Ai; Toyama, Hiroshi; Kato, Ryouichi</p> <p>2016-07-08</p> <p>The primary study objective was to assess radiation doses using a modified form of the Imaging Performance Assessment of Computed Tomography (CT) scanner (<span class="hlt">Im</span>PACT) patient dosimetry for cardiac applications on an Aquilion ONE ViSION Edition scanner, including the Ca score, target computed tomography angiography (CTA), prospective CTA, continuous CTA/cardiac function analysis (CFA), and CTA/CFA modulation. Accordingly, we clarified the CT dose index (CTDI) to determine the relationship between heart rate (HR) and X-ray exposure. As a secondary objective, we compared radiation doses using modified <span class="hlt">Im</span>PACT, a whole-body dosimetry phantom study, and the k-factor method to verify the validity of the dose results obtained with modified <span class="hlt">Im</span>PACT. The effective dose determined for the reference person (4.66 mSv at 60 beats per minute (bpm) and 33.43 mSv at 90bpm) were approximately 10% less than those determined for the phantom study (5.28 mSv and 36.68 mSv). The effective doses according to the k-factor (0.014 mSv•mGy-1•cm-1; 2.57 mSv and 17.10 mSv) were significantly lower than those obtained with the other two methods. In the present study, we have shown that <span class="hlt">Im</span>PACT, when modified for cardiac applications, can assess both absorbed and effective doses. The results of our dose comparison indicate that modified <span class="hlt">Im</span>PACT dose assessment is a promising and practical method for evaluating coronary CTA.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..18.5544G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..18.5544G"><span>Detection capability of the <span class="hlt">IMS</span> seismic network based on ambient seismic noise measurements</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gaebler, Peter J.; Ceranna, Lars</p> <p>2016-04-01</p> <p>All nuclear explosions - on the Earth's surface, underground, underwater or in the atmosphere - are banned by the Comprehensive Nuclear-Test-Ban Treaty (CTBT). As part of this treaty, a verification regime was put into place to detect, locate and characterize nuclear explosion testings at any time, by anyone and everywhere on the Earth. The International Monitoring System (<span class="hlt">IMS</span>) plays a key role in the verification regime of the CTBT. Out of the different monitoring techniques used in the <span class="hlt">IMS</span>, the seismic waveform approach is the most effective technology for monitoring nuclear underground testing and to identify and characterize potential nuclear events. This study introduces a method of seismic threshold monitoring to assess an upper magnitude limit of a potential seismic event in a certain given geographical region. The method is based on ambient seismic background noise measurements at the individual <span class="hlt">IMS</span> seismic stations as well as on global distance correction terms for body wave magnitudes, which are calculated using the seismic reflectivity method. From our investigations we conclude that a global detection threshold of around mb 4.0 can be achieved using only stations from the primary seismic network, a clear latitudinal dependence for the detection threshold can be observed between northern and southern hemisphere. Including the seismic stations being part of the auxiliary seismic <span class="hlt">IMS</span> network results in a slight improvement of global detection capability. However, including wave arrivals from distances greater than 120 degrees, mainly PKP-wave arrivals, leads to a significant improvement in average global detection capability. In special this leads to an improvement of the detection threshold on the southern hemisphere. We further investigate the dependence of the detection capability on spatial (latitude and longitude) and temporal (time) parameters, as well as on parameters such as source type and percentage of operational <span class="hlt">IMS</span> stations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/974911','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/974911"><span>An LC-<span class="hlt">IMS</span>-MS Platform Providing Increased Dynamic Range for High-Throughput Proteomic Studies</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Baker, Erin Shammel; Livesay, Eric A.; Orton, Daniel J.; Moore, Ronald J.; Danielson, William F.; Prior, David C.; Ibrahim, Yehia M.; Lamarche, Brian L.; Mayampurath, Anoop M.; Schepmoes, Athena A.; Hopkins, Derek F.; Tang, Keqi; Smith, Richard D.; Belov, Mikhail E.</p> <p>2010-02-05</p> <p>A high-throughput approach and platform using 15 minute reversed-phase capillary liquid chromatography (RPLC) separations in conjunction with ion mobility spectrometry-mass spectrometry (<span class="hlt">IMS</span>-MS) measurements was evaluated for the rapid analysis of complex proteomics samples. To test the separation quality of the short LC gradient, a sample was prepared by spiking twenty reference peptides at varying concentrations from 1 ng/mL to 10 µg/mL into a tryptic digest of mouse blood plasma and analyzed with both a LC-Linear Ion Trap Fourier Transform (FT) MS and LC-<span class="hlt">IMS</span>-TOF MS. The LC-FT MS detected thirteen out of the twenty spiked peptides that had concentrations ≥100 ng/mL. In contrast, the drift time selected mass spectra from the LC-<span class="hlt">IMS</span>-TOF MS analyses yielded identifications for nineteen of the twenty peptides with all spiking level present. The greater dynamic range of the LC-<span class="hlt">IMS</span>-TOF MS system could be attributed to two factors. First, the LC-<span class="hlt">IMS</span>-TOF MS system enabled drift time separation of the low concentration spiked peptides from the high concentration mouse peptide matrix components, reducing signal interference and background, and allowing species to be resolved that would otherwise be obscured by other components. Second, the automatic gain control (AGC) in the linear ion trap of the hybrid FT MS instrument limits the number of ions that are accumulated to reduce space charge effects, but in turn limits the achievable dynamic range compared to the TOF detector.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110008222','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110008222"><span>Automation of PCXMC and <span class="hlt">Im</span>PACT for NASA Astronaut Medical Imaging Dose and Risk Tracking</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Bahadori, Amir; Picco, Charles; Flores-McLaughlin, John; Shavers, Mark; Semones, Edward</p> <p>2011-01-01</p> <p>To automate astronaut organ and effective dose calculations from occupational X-ray and computed tomography (CT) examinations incorporating PCXMC and <span class="hlt">Im</span>PACT tools and to estimate the associated lifetime cancer risk per the National Council on Radiation Protection & Measurements (NCRP) using MATLAB(R). Methods: NASA follows guidance from the NCRP on its operational radiation safety program for astronauts. NCRP Report 142 recommends that astronauts be informed of the cancer risks from reported exposures to ionizing radiation from medical imaging. MATLAB(R) code was written to retrieve exam parameters for medical imaging procedures from a NASA database, calculate associated dose and risk, and return results to the database, using the Microsoft .NET Framework. This code interfaces with the PCXMC executable and emulates the <span class="hlt">Im</span>PACT Excel spreadsheet to calculate organ doses from X-rays and CTs, respectively, eliminating the need to utilize the PCXMC graphical user interface (except for a few special cases) and the <span class="hlt">Im</span>PACT spreadsheet. Results: Using MATLAB(R) code to interface with PCXMC and replicate <span class="hlt">Im</span>PACT dose calculation allowed for rapid evaluation of multiple medical imaging exams. The user inputs the exam parameter data into the database and runs the code. Based on the imaging modality and input parameters, the organ doses are calculated. Output files are created for record, and organ doses, effective dose, and cancer risks associated with each exam are written to the database. Annual and post-flight exposure reports, which are used by the flight surgeon to brief the astronaut, are generated from the database. Conclusions: Automating PCXMC and <span class="hlt">Im</span>PACT for evaluation of NASA astronaut medical imaging radiation procedures allowed for a traceable and rapid method for tracking projected cancer risks associated with over 12,000 exposures. This code will be used to evaluate future medical radiation exposures, and can easily be modified to accommodate changes to the risk</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012ApJS..201....5R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012ApJS..201....5R"><span>VLBI for Gravity Probe B. V. Proper Motion and Parallax of the Guide Star, <span class="hlt">IM</span> Pegasi</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ratner, M. I.; Bartel, N.; Bietenholz, M. F.; Lebach, D. E.; Lestrade, J.-F.; Ransom, R. R.; Shapiro, I. I.</p> <p>2012-07-01</p> <p>We present the principal astrometric results of the very long baseline interferometry (VLBI) program undertaken in support of the Gravity Probe B (GP-B) relativity mission. VLBI observations of the GP-B guide star, the RS CVn binary <span class="hlt">IM</span> Pegasi (HR 8703), yielded positions at 35 epochs between 1997 and 2005. We discuss the statistical assumptions behind these results and our methods for estimating the systematic errors. We find the proper motion of <span class="hlt">IM</span> Peg in an extragalactic reference frame closely related to the International Celestial Reference Frame 2 (ICRF2) to be -20.83 ± 0.03 ± 0.09 mas yr-1 in right ascension and -27.27 ± 0.03 ± 0.09 mas yr-1 in declination. For each component, the first uncertainty is the statistical standard error and the second is the total standard error (SE) including plausible systematic errors. We also obtain a parallax of 10.37 ± 0.07 mas (distance: 96.4 ± 0.7 pc), for which there is no evidence of any significant contribution of systematic error. Our parameter estimates for the ~25 day period orbital motion of the stellar radio emission have SEs corresponding to ~0.10 mas on the sky in each coordinate. The total SE of our estimate of <span class="hlt">IM</span> Peg's proper motion is ~30% smaller than the accuracy goal set by the GP-B project before launch: 0.14 mas yr-1 for each coordinate of <span class="hlt">IM</span> Peg's proper motion. Our results ensure that the uncertainty in <span class="hlt">IM</span> Peg's proper motion makes only a very small contribution to the uncertainty of the GP-B relativity tests.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22047729','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22047729"><span>VLBI FOR GRAVITY PROBE B. V. PROPER MOTION AND PARALLAX OF THE GUIDE STAR, <span class="hlt">IM</span> PEGASI</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ratner, M. I.; Lebach, D. E.; Shapiro, I. I.; Bartel, N.; Bietenholz, M. F.; Ransom, R. R.; Lestrade, J.-F.</p> <p>2012-07-01</p> <p>We present the principal astrometric results of the very long baseline interferometry (VLBI) program undertaken in support of the Gravity Probe B (GP-B) relativity mission. VLBI observations of the GP-B guide star, the RS CVn binary <span class="hlt">IM</span> Pegasi (HR 8703), yielded positions at 35 epochs between 1997 and 2005. We discuss the statistical assumptions behind these results and our methods for estimating the systematic errors. We find the proper motion of <span class="hlt">IM</span> Peg in an extragalactic reference frame closely related to the International Celestial Reference Frame 2 (ICRF2) to be -20.83 {+-} 0.03 {+-} 0.09 mas yr{sup -1} in right ascension and -27.27 {+-} 0.03 {+-} 0.09 mas yr{sup -1} in declination. For each component, the first uncertainty is the statistical standard error and the second is the total standard error (SE) including plausible systematic errors. We also obtain a parallax of 10.37 {+-} 0.07 mas (distance: 96.4 {+-} 0.7 pc), for which there is no evidence of any significant contribution of systematic error. Our parameter estimates for the {approx}25 day period orbital motion of the stellar radio emission have SEs corresponding to {approx}0.10 mas on the sky in each coordinate. The total SE of our estimate of <span class="hlt">IM</span> Peg's proper motion is {approx}30% smaller than the accuracy goal set by the GP-B project before launch: 0.14 mas yr{sup -1} for each coordinate of <span class="hlt">IM</span> Peg's proper motion. Our results ensure that the uncertainty in <span class="hlt">IM</span> Peg's proper motion makes only a very small contribution to the uncertainty of the GP-B relativity tests.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24151810','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24151810"><span>Invalid performance and the <span class="hlt">Im</span>PACT in national collegiate athletic association division I football players.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Szabo, Ashley J; Alosco, Michael L; Fedor, Andrew; Gunstad, John</p> <p>2013-01-01</p> <p>Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) is a computerized cognitive test battery commonly used for concussion evaluation. An important aspect of these procedures is baseline testing, but researchers have suggested that many users do not use validity indices to ensure adequate effort during testing. No one has examined the prevalence of invalid performance for college football players. To examine the prevalence of invalid scores on <span class="hlt">Im</span>PACT testing. Cross-sectional study. National Collegiate Athletic Association Division I university. A total of 159 athletes (age = 20.3 ± 1.41 years; range = 17.8-23.7 years) from a Division I collegiate football team participated. An informational intervention regarding the importance of concussion testing to promote safety was administered before testing for the most recent season. We examined preseason <span class="hlt">Im</span>PACT testing data across a 3-year period (total assessments = 269). Based on invalid and sandbagging indices denoted by the <span class="hlt">Im</span>PACT manual, protocols were examined to indicate how many invalid indices each athlete had. A total of 27.9% (n = 75) of assessments were suggestive of invalid scores, with 4.1% (n = 11) suggesting invalid responding only, 17.5% (n = 47) indicating "sandbagging" only, and 6.3% (n = 17) showing both invalid and sandbagging responding. The informational intervention did not reduce the prevalence of invalid responding. These findings highlight the need for further information about the <span class="hlt">Im</span>PACT validity indices and whether they truly reflect poor effort. Future work is needed to identify practices to reliably target and reduce invalid responding.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110022428','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110022428"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa, Ganymede, and the Jovian Systems</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Sittler, E.; Cooper, J.; Hartle, R.; Paterson ,W.; Christian, E.; Mahaffy, P.; Paschalidis, N.; Lipatov, A.; Sarantos, M.; Coplan, M.; Cassidy, T.; Wurz, P.</p> <p>2011-01-01</p> <p>NASA and ESA are now planning a reduced version of the joint Europa Jupiter System Mission (EJSM), potentially including a radically descoped Jupiter Europa Orbiter (JEO) but still with magnetometer and plasma instruments. Similar field and plasma instrumentation would also reside on ESA's Jupiter Ganymede Orbiter (JGO), which conceivably could carry out multiple flybys of Europa before entering orbit at Ganymede. We are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) designed to measure both major and minor ion species within the high radiation environment of Jupiter s magnetosphere and the icy Galilean moons. The <span class="hlt">IMS</span> covers the energy range from 10 eV to 30 keV, wide field-ofview (FOV) capability and 10-60 sec time resolution for major ions. This instrument has two main goals: 1) measure the plasma interaction between Europa and Jupiter s magnetosphere and 2) infer the global surface composition to trace elemental and significant isotopic levels; these goals are also applicable for in-situ measurements at Ganymede and Callisto, and remotely everywhere via the iogenic plasma for Io. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa's sub-surface ocean, while the second goal gives information about transfer of material between the Galilean moons, e.g. mainly from Io to the other moons, and further allows detection of oceanic materials emergent to the moon surfaces from subsurface layers putatively including salt water oceans. Outgassed exospheric materials are probed by the <span class="hlt">IMS</span> by measuring pickup ions accelerated up to spacecraft altitudes of approximately 100-200 km in electric fields extending through the local magnetospheric environment and moon exosphere to the surface. Our 3D hybrid kinetic model of the moon-magnetosphere interaction is used to construct a global model of electric and magnetic fields for tracing of pickup ion trajectories back to the sources at approximate surface resolution of 100 km. We</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110015200','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110015200"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa, Ganymede, and the Jovian System</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Sittler, E. C., Jr.; Cooper, J. F.; Hartle, R. E.; Paterson, W. R.; Christian, E. R.; Lipatov, A. S.; Mahaffy, P R.; Paschalidis, N.; Sarantos, M.; Coplan, M. A.; Cassidy, T. A.; Wurz, P.</p> <p>2011-01-01</p> <p>NASA and ESA are now planning a reduced version of the joint Europa Jupiter System Mission (EJSM), potentially including a radically descoped Jupiter Europa Orbiter (JEO) but still with magnetometer and plasma instruments. Similar field and plasma instrumentation would also reside on ESA's Jupiter Ganymede Orbiter (JGO), which conceivably could carry out multiple flybys of Europa before entering orbit at Ganymede. We are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) designed to measure both major and minor ion species within the high radiation environment of Jupiter's magnetosphere and the icy Galilean moons. The <span class="hlt">IMS</span> covers the energy range from 10 eV to 30 keY, wide field-of-view (FOV) capability and 10-60 sec time resolution for major ions. This instrument has two main goals: 1) measure the plasma interaction between Europa and Jupiter's magnetosphere and 2) infer the global surface composition to trace elemental and significant isotopic levels; these goals are also applicable for in-situ measurements at Ganymede and Callisto, and remotely everywhere via the iogenic plasma for 10. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa's sub-surface ocean, while the second goal gives information about transfer of material between the Galilean moons, e.g. mainly from 10 to the other moons, and further allows detection of oceanic materials emergent to the moon surfaces from subsurface layers putatively including salt water oceans. Outgassed exospheric materials are probed by the <span class="hlt">IMS</span> by measuring pickup ions accelerated up to spacecraft altitudes of approximately 100-200 km in electric fields extending through the local magnetospheric environment and moon exosphere to the surface. Our 3D hybrid kinetic model of the moon-magnetosphere interaction is used to construct a global model of electric and magnetic fields for tracing of pickup ion trajectories back to the sources at approximate surface resolution of 100 km. We</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27525174','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27525174"><span>UTILIZATION OF <span class="hlt">Im</span>PACT TESTING TO MEASURE INJURY RISK IN ALPINE SKI AND SNOWBOARD ATHLETES.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Faltus, John; Huntimer, Brittney; Kernozek, Thomas; Cole, John</p> <p>2016-08-01</p> <p>While studies that have examined the prevalence of musculoskeletal injuries in alpine skiing and snowboarding exist, there has been no discussion of how neurocognitive deficits may influence such injuries. Recent authors have identified a possible link between Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) testing results and the prevalence of musculoskeletal injury in athletic populations. However, no study has specifically examined this in the alpine skiing and snowboard athletes who sustain injury and those that do not. The purpose was to review injury data and <span class="hlt">Im</span>PACT test results within the local ski/snowboard population to determine if there was a difference in components of <span class="hlt">Im</span>PACT test scores between injured and non-injured athletes. It was hypothesized that differences would exist in component scores on <span class="hlt">Im</span>PACT testing between injured and non-injured athletes. Retrospective cohort study. Injury records and baseline <span class="hlt">Im</span>PACT testing scores for 93 athletes aged 14-17 participating in a local ski and snowboard club during the 2009-2012 seasons were gathered retrospectively. Injuries documented for the lower and upper extremity included ligament sprains, muscle strains, contusions, dislocation/subluxation, fractures and concussions. Athletes who sustained any of these listed injuries were categorized within the injured athlete group. Each component of <span class="hlt">Im</span>PACT test scores was compared between gender and for injury status within skiing and snowboarding disciplines using a series of two-way analysis of variance tests. There was no difference between non-injured and injured females as well as non-injured and injured males in reaction time and visual motor speed (VMS), however there was an interaction between gender and injury status on composite reaction time and visual motor speed, or VMS. The composite reaction time for females was 4.7% faster with injury while males without injury had a composite reaction time that was slower by 5.8%. Females had</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4970840','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4970840"><span>UTILIZATION OF <span class="hlt">Im</span>PACT TESTING TO MEASURE INJURY RISK IN ALPINE SKI AND SNOWBOARD ATHLETES</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Huntimer, Brittney; Kernozek, Thomas; Cole, John</p> <p>2016-01-01</p> <p>ABSTRACT Background While studies that have examined the prevalence of musculoskeletal injuries in alpine skiing and snowboarding exist, there has been no discussion of how neurocognitive deficits may influence such injuries. Recent authors have identified a possible link between Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) testing results and the prevalence of musculoskeletal injury in athletic populations. However, no study has specifically examined this in the alpine skiing and snowboard athletes who sustain injury and those that do not. Hypothesis/Purpose The purpose was to review injury data and <span class="hlt">Im</span>PACT test results within the local ski/snowboard population to determine if there was a difference in components of <span class="hlt">Im</span>PACT test scores between injured and non-injured athletes. It was hypothesized that differences would exist in component scores on <span class="hlt">Im</span>PACT testing between injured and non-injured athletes. Study design Retrospective cohort study Methods Injury records and baseline <span class="hlt">Im</span>PACT testing scores for 93 athletes aged 14-17 participating in a local ski and snowboard club during the 2009-2012 seasons were gathered retrospectively. Injuries documented for the lower and upper extremity included ligament sprains, muscle strains, contusions, dislocation/subluxation, fractures and concussions. Athletes who sustained any of these listed injuries were categorized within the injured athlete group. Each component of <span class="hlt">Im</span>PACT test scores was compared between gender and for injury status within skiing and snowboarding disciplines using a series of two-way analysis of variance tests. Results There was no difference between non-injured and injured females as well as non-injured and injured males in reaction time and visual motor speed (VMS), however there was an interaction between gender and injury status on composite reaction time and visual motor speed, or VMS. The composite reaction time for females was 4.7% faster with injury while males without injury</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27039710','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27039710"><span>Cd(ii)-MOF-<span class="hlt">IM</span>: post-synthesis functionalization of a Cd(ii)-MOF as a triphase transfer catalyst.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wang, Jian-Cheng; Ma, Jian-Ping; Liu, Qi-Kui; Hu, Yu-Hong; Dong, Yu-Bin</p> <p>2016-05-19</p> <p>A robust and porous Cd(ii)-MOF based on a bent imidazole-bridged ligand was synthesized and post-synthetically functionalized with linear alkyl chains to afford imidazolium salt (<span class="hlt">IM</span>)-type triphase transfer catalysts for organic transformations. The imidazolium salt decorated Cd(ii)-MOF-<span class="hlt">IM</span> exhibits typical solid phase transfer catalytic behavior for the azidation and thiolation of bromoalkane between aqueous/organic phases. Moreover, they can be easily recovered and reused under the PTC conditions. Cd(ii)-MOF-<span class="hlt">IM</span> herein created a versatile family of solid phase transfer catalysts for promoting a broad scope of reactions carried out in a biphasic mixture of two immiscible solvents.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1108127','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1108127"><span>LC-<span class="hlt">IMS</span>-MS Feature Finder. Detecting Multidimensional Liquid Chromatography, Ion Mobility, and Mass Spectrometry Features in Complex Datasets</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Crowell, Kevin L.; Slysz, Gordon W.; Baker, Erin Shammel; Lamarche, Brian L.; Monroe, Matthew E.; Ibrahim, Yehia M.; Payne, Samuel H.; Anderson, Gordon A.; Smith, Richard D.</p> <p>2013-09-05</p> <p>We introduce a command line software application LC-<span class="hlt">IMS</span>-MS Feature Finder that searches for molecular ion signatures in multidimensional liquid chromatography-ion mobility spectrometry-mass spectrometry (LC-<span class="hlt">IMS</span>-MS) data by clustering deisotoped peaks with similar monoisotopic mass, charge state, LC elution time, and ion mobility drift time values. The software application includes an algorithm for detecting and quantifying co-eluting chemical species, including species that exist in multiple conformations that may have been separated in the <span class="hlt">IMS</span> dimension.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27497965','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27497965"><span>Contaminant screening of wastewater with HPLC-<span class="hlt">IM</span>-qTOF-MS and LC+LC-<span class="hlt">IM</span>-qTOF-MS using a CCS database.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stephan, Susanne; Hippler, Joerg; Köhler, Timo; Deeb, Ahmad A; Schmidt, Torsten C; Schmitz, Oliver J</p> <p>2016-09-01</p> <p>Non-target analysis has become an important tool in the field of water analysis since a broad variety of pollutants from different sources are released to the water cycle. For identification of compounds in such complex samples, liquid chromatography coupled to high resolution mass spectrometry are often used. The introduction of ion mobility spectrometry provides an additional separation dimension and allows determining collision cross sections (CCS) of the analytes as a further physicochemical constant supporting the identification. A CCS database with more than 500 standard substances including drug-like compounds and pesticides was used for CCS data base search in this work. A non-target analysis of a wastewater sample was initially performed with high performance liquid chromatography (HPLC) coupled to an ion mobility-quadrupole-time of flight mass spectrometer (<span class="hlt">IM</span>-qTOF-MS). A database search including exact mass (±5 ppm) and CCS (±1 %) delivered 22 different compounds. Furthermore, the same sample was analyzed with a two-dimensional LC method, called LC+LC, developed in our group for the coupling to <span class="hlt">IM</span>-qTOF-MS. This four dimensional separation platform revealed 53 different compounds, identified over exact mass and CCS, in the examined wastewater sample. It is demonstrated that the CCS database can also help to distinguish between isobaric structures exemplified for cyclophosphamide and ifosfamide. Graphical Abstract Scheme of sample analysis and database screening.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1060124','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1060124"><span>Evaluation of SDS depletion using an affinity spin column and <span class="hlt">IMS</span>-MS detection</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Hengel, Shawna M.; Floyd, Erica A.; Baker, Erin Shammel; Zhao, Rui; Wu, Si; Pasa-Tolic, Ljiljana</p> <p>2012-11-01</p> <p>While the use of detergents is necessary for a variety of protein isolation preparation protocols, often prior to mass spectral (MS) analysis, they are not compatible with MS analysis due to ion suppression and adduct formation. This manuscript describes optimization of detergent removal, using commercially available SDS depletion spin columns containing an affinity resin, providing for both increased protein recovery and thorough SDS removal. Ion mobility spectrometry coupled with mass spectrometry (<span class="hlt">IMS</span>-MS) allowed for a concurrent analysis of both analyte and detergent. In the case of both proteins and peptides, higher detergent concentrations than previously reported provided an increase of sample recovery; however there was a limit as SDS was detected by <span class="hlt">IMS</span>-MS at higher levels of SDS indicating incomplete detergent depletion. The results also suggest optimal conditions for SDS removal are dependent on the sample concentration. Overall, this study provides a useful guide for proteomic studies where SDS is required for efficient sample preparation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/6623243','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/6623243"><span>Hot plasma and energetic particles in the earth's outer magnetosphere: new understandings during the <span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Baker, D.N.; Fritz, T.A.</p> <p>1984-01-01</p> <p>In this paper we review the major accomplishments made during the <span class="hlt">IMS</span> period in clarifying magnetospheric particle variations in the region from roughly geostationary orbit altitudes into the deep magnetotail. We divide our review into three topic areas: (1) acceleration processes; (2) transport processes; and (3) loss processes. Many of the changes in hot plasmas and energetic particle populations are often found to be related intimately to geomagnetic storm and magnetospheric substorm effects and, therefore, substantial emphasis is given to these aspects of particle variations in this review. The <span class="hlt">IMS</span> data, taken as a body, allow a reasonably unified view as one traces magnetospheric particles from their acceleration source through the plasma sheet and outer trapping regions and, finally, to their loss via ionospheric precipitation and ring current formation processes. It is this underlying, unifying theme which is pursued here. 52 references, 19 figures.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_13 --> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EPJST.226.2955X','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EPJST.226.2955X"><span>Ion source for <span class="hlt">IMS</span> based on wire-to-plate corona discharge</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Xia, Qing; Zhang, Yu; Ouyang, Jiting</p> <p>2017-08-01</p> <p>In this paper, an ion source based on wire-to-plate corona is developed for Ion Mobility Spectrometer (<span class="hlt">IMS</span>). The characteristics of the corona discharge and the ion current detected on Faraday plate are investigated under different electrode spacing and voltage. The effect of voltage polarity is also studied. The features of this new designed ion source are compared with that of point-to-plate corona. The results show that the present <span class="hlt">IMS</span> prototype machine can provide a much larger value of ion current connected by Faraday plate than the point-to-plate corona and/or the traditional 63Ni source. The corona configuration can also act as a good electromagnetic shielding to defense the electromagnetic emission from the corona discharge.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4804111','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4804111"><span>Two-year Test–Retest Reliability of <span class="hlt">Im</span>PACT in High School Athletes</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Tsushima, William T.; Siu, Andrea M.; Pearce, Annina M.; Zhang, Guangxiang; Oshiro, Ross S.</p> <p>2016-01-01</p> <p>This research evaluated the 2-year test–retest reliability of the Immediate Postconcussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) neuropsychological battery, and clarified the need for biennial updated baseline testing of high school athletes. This study compared the baseline test scores of 212 non-concussed athletes that were obtained in Grade 9 and again 2 years later when they were in Grade 11. Regression-based methods indicated that 4 of the 5 <span class="hlt">Im</span>PACT scores were stable over 2 years, as they fell within the 80% and 95% confidence intervals (CIs). The results suggested that updating baseline testing for high school athletes after 2 years is not necessary. Further research into the consistency of computerized neuropsychological tests over 2 years with high school athletes is recommended. PMID:26572159</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004ZAGeo..28...73K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004ZAGeo..28...73K"><span>Das Programm Oder 2006. Hochwasserschutz in Polen <span class="hlt">im</span> Zuge der EU-Osterweiterung</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kühne, Olaf</p> <p></p> <p>Hochwasser ist ein natürliches Ereignis: Seit jeher sind die Menschen mit Hochwasser und seinen Auswirkungen konfrontiert. Das Ausmaß von Hochwasser reicht dabei von Straßenüberschwemmungen bis zur Überflutung ganzer Landesteile. Auch <span class="hlt">im</span> Oderflußsystem waren und sind Überschwemmungen keine Seltenheit, in den letzten 200 Jahren ereigneten sie sich in den Jahren 1813, 1838, 1854, 1870, 1903, 1958, 1965, 1970, 1972, 1977, 1981, 1985 und 1997. Das Hochwasser von 1997 war jedoch das schwerste <span class="hlt">im</span> genannten Zeitraum. Als Reaktion auf das Hochwasser von 1997 wurde in der betroffenen Region das Programm 〝Oder 2006`` entwickelt. Mit seiner Hilfe sollen die Auswirkungen künftiger Hochwasserereignisse abgeschwächt werden.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25506826','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25506826"><span><span class="hlt">IM</span>-TORNADO: a tool for comparison of 16S reads from paired-end libraries.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jeraldo, Patricio; Kalari, Krishna; Chen, Xianfeng; Bhavsar, Jaysheel; Mangalam, Ashutosh; White, Bryan; Nelson, Heidi; Kocher, Jean-Pierre; Chia, Nicholas</p> <p>2014-01-01</p> <p>16S rDNA hypervariable tag sequencing has become the de facto method for accessing microbial diversity. Illumina paired-end sequencing, which produces two separate reads for each DNA fragment, has become the platform of choice for this application. However, when the two reads do not overlap, existing computational pipelines analyze data from read separately and underutilize the information contained in the paired-end reads. We created a workflow known as Illinois Mayo Taxon Organization from RNA Dataset Operations (<span class="hlt">IM</span>-TORNADO) for processing non-overlapping reads while retaining maximal information content. Using synthetic mock datasets, we show that the use of both reads produced answers with greater correlation to those from full length 16S rDNA when looking at taxonomy, phylogeny, and beta-diversity. <span class="hlt">IM</span>-TORNADO is freely available at http://sourceforge.net/projects/imtornado and produces BIOM format output for cross compatibility with other pipelines such as QIIME, mothur, and phyloseq.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/9670484','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/9670484"><span>Detection of designer drugs in human hair by ion mobility spectrometry (<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Keller, T; Miki, A; Regenscheit, P; Dirnhofer, R; Schneider, A; Tsuchihashi, H</p> <p>1998-06-08</p> <p>Since its inception in the early 1970s under the name plasma chromatography, ion mobility spectrometry (<span class="hlt">IMS</span>) has undergone great changes. It is now utilized more and more in forensic science laboratories where it is used to detect explosives and environmental pollutants [1-4] as well as its use in detecting drugs of abuse [5-8]. Although <span class="hlt">IMS</span> is known for nearly 30 years now [9], relatively few cases of the application of ion mobility spectrometry to the analysis of human hair have been reported [10-12]. The authors report a new and quick method to rapidly screen and determine MDMA ('ecstasy', 'Adam') and MDEA ('Eve') in human hair. The proposed method using trihexylamine as internal standard resulted in a rapid procedure useful in screening human hair specimens for designer drugs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/697206','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/697206"><span>[Acute poisoning by <span class="hlt">I.M</span>. iron. Report of a fatal case (author's transl)].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Menéndez, M; Galbe, M; Antuńa, M J; Del Campo, M A; Rodríguez-Vigil, E</p> <p>1978-04-01</p> <p>The case of a five months-old child who received 44 mg/Kg of Fe-sorbitol <span class="hlt">I.M</span>. by mistake is reported. That dose is about ten times the usual standard dosage. After an initial vague symptomatology, followed by transitory improvement, she developed a serious metabolic acidosis, renal and hepatic failure and generalized convulsions. The clinical picture could not be controlled by general supportive treatment, desferroxamine administration and exanguino-transfusion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA405215','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA405215"><span>USACE IT/<span class="hlt">IM</span> Migration Strategy. Decision Briefing Board of Directors</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1998-02-05</p> <p>for public release, distribution unlimited Supplementary Notes Abstract Subject Terms Report Classification unclassified Classification of this...page unclassified Classification of Abstract unclassified Limitation of Abstract UU Number of Pages 25 2/5/98 2 Agenda l Mission l IT/<span class="hlt">IM</span> Strategic...n Redundancy to District level n All Corps of Engineers has access to CEAP Cost n 56 kbps = 900K (Annual) Tech n T-3 ATM to 7 CONUS Division HQ n 2 T</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA456396','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA456396"><span>JFACC Information Management (<span class="hlt">IM</span>) Capability - 2010. Functional Decomposition of Operational Activities - Version 1.0</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2004-12-01</p> <p>The JFACC Information Management (<span class="hlt">IM</span>) Functional Decomposition of Operational Activities provides the hierarchy of activities for the Joint Force Air...within a theater or geographic region and outlines the conceptual baseline . The Functional Decomposition has five major sections; Provide Information ... Management /Net-centricity Governance (1.1 series), Manage Information/Net-centric Data Accessibility (1.2 series), Manage Net-centric Data (1.3 series</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11382026','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11382026"><span>[Analysis on effect of inspection and maintenance (<span class="hlt">I/M</span>) program for vehicle emission reduction].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhang, H; Fu, L; Hao, J; Zhou, Z; Wang, X</p> <p>2001-01-01</p> <p>An Inspection and maintenance(I/M) programme aims to ensure that motor vehicle emission control systems are functioning properly throughout the two stage idle test. Based on three factors including data from inspection, standard for inspection and failure rate, the effectiveness of the current <span class="hlt">I/M</span> program was studied through the cumulative distributions. The disadvantages of the cutpoints, institution settings, management, and supervision was also analyzed. The fundamental law of emission limits was proposed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19830035060&hterms=IMP&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DIMP','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19830035060&hterms=IMP&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DIMP"><span>Availability of IMP-7 and IMP-8 data for the <span class="hlt">IMS</span> period</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>King, J. H.</p> <p>1982-01-01</p> <p>The relation of IMP-7 and IMP-8 data to the International Magnetospheric Study is discussed. Relevant spacecraft and experiment characteristics, and the nature and accessibility of data from each experiment, are identified. Finally the potential value of IMP data in <span class="hlt">IMS</span> studies is illustrated with a few citations from the IMP Bibliography and with figures from a recent multiple-data-set magnetotail plasma sheet study.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..12.8491W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..12.8491W"><span>Assessment of the readiness of noble gas equipment for field operation in the <span class="hlt">IMS</span> network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wernsperger, Bernd; Auer, Matthias; Gohla, Herbert; Khrustalev, Kirill</p> <p>2010-05-01</p> <p>The radionuclide component of the International Monitoring System (<span class="hlt">IMS</span>) consists of 80 radionuclide stations, of which 40 are equipped with noble-gas monitoring capability. Prior to the set-up of the <span class="hlt">IMS</span> network, noble gas monitoring was only performed by a few institutions using manual, laboratory based systems. The deployment of noble gas systems in a world-wide network of monitoring stations required development of a new generation of equipment, which is reliable, suited for automated field operation at a detection sensitivity lower than previously achieved in laboratory based systems. New types of equipment have been developed and undergone extensive testing during the last 10 years under the framework of the ongoing International Noble Gas Experiment (INGE). During Phase III of INGE, three different types of noble gas systems are deployed into the <span class="hlt">IMS</span> for testing. With altogether 17 systems in the field between 2004 to 2008 experience of more than 37 operational years has been accumulated. Operational parameters of the noble gas systems have improved during the entire Phase III from the first systems towards the latest state-of the art system generations. To ensure minimum down time any operational problems are addressed within the support system inside the PTS. Within this support system the operational performance is continuously monitored and particular problems are identified. The solution of operational problems is the joint objective of the PTS, the station operators and the system suppliers. Equipment reliability, operational procedures, maintenance and sparing plans are continuously reviewed and improved. The operational status of the <span class="hlt">IMS</span> noble gas network during the Phase III exercise as well as the support strategy is presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013MNRAS.434.1604Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013MNRAS.434.1604Z"><span><span class="hlt">IM</span>3SHAPE: a maximum likelihood galaxy shear measurement code for cosmic gravitational lensing</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zuntz, Joe; Kacprzak, Tomasz; Voigt, Lisa; Hirsch, Michael; Rowe, Barnaby; Bridle, Sarah</p> <p>2013-09-01</p> <p>We present and describe <span class="hlt">IM</span>3SHAPE, a new publicly available galaxy shape measurement code for weak gravitational lensing shear. <span class="hlt">IM</span>3SHAPE performs a maximum likelihood fit of a bulge-plus-disc galaxy model to noisy images, incorporating an applied point spread function. We detail challenges faced and choices made in its design and implementation, and then discuss various limitations that affect this and other maximum likelihood methods. We assess the bias arising from fitting an incorrect galaxy model using simple noise-free images and find that it should not be a concern for current cosmic shear surveys. We test <span class="hlt">IM</span>3SHAPE on the Gravitational Lensing Accuracy Testing 2008 (GREAT08) challenge image simulations, and meet the requirements for upcoming cosmic shear surveys in the case that the simulations are encompassed by the fitted model, using a simple correction for image noise bias. For the fiducial branch of GREAT08 we obtain a negligible additive shear bias and sub-two per cent level multiplicative bias, which is suitable for analysis of current surveys. We fall short of the sub-per cent level requirement for upcoming surveys, which we attribute to a combination of noise bias and the mismatch between our galaxy model and the model used in the GREAT08 simulations. We meet the requirements for current surveys across all branches of GREAT08, except those with small or high noise galaxies, which we would cut from our analysis. Using the GREAT08 metric we we obtain a score of Q = 717 for the usable branches, relative to the goal of Q = 1000 for future experiments. The code is freely available from https://bitbucket.org/joezuntz/<span class="hlt">im</span>3shape</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27919505','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27919505"><span>Persian adaptation of a questionnaire of environmental risk factors in multiple sclerosis (Env<span class="hlt">IMS</span>-Q).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sahraian, Mohammad Ali; Naghshineh, Hoda; Shati, Mohsen; Jahromi, Soodeh Razeghi; Rezaei, Niloofar</p> <p>2016-11-01</p> <p>It seems that gene-environment interaction play most important role in Multiple Sclerosis development. Increasing the incidence and prevalence of MS during the recent decades in the low prevalence area such as Iran is explained better by environment factors. Environmental Risk Factors in Multiple Sclerosis (the 'Env<span class="hlt">IMS</span>-Q') is a 6-page self-administered questionnaire for case control studies. the objectives of study are validation and adaptation of the Env<span class="hlt">IMS</span>-Q' then development of a Persian version for case control studies in Persian population. This questionnaire translated literally and in culturally relevant form, then content validation process was done by three groups' experts. According to giving rating to each item, each section and the whole instrument, we calculated their content validation indexes and also added some new questions and a new section to Env<span class="hlt">IMS</span>-Q. Finally, we analyzed repeatability of the answers within a 4 weeks interval. Relevancy and clarity indexes of all items were more than 80%. Scale relevancy index equaled 99% and scale clarity index equaled 97%. Repeatability of most items was acceptable. the use of standardized validated questionnaires will assist the researchers to perform local studies on the role of environmental factors on the basis of reliable data. Copyright © 2016 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28704718','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28704718"><span>Calibration and validation of a MCC/<span class="hlt">IMS</span> prototype for exhaled propofol online measurement.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Maurer, Felix; Walter, Larissa; Geiger, Martin; Baumbach, Jörg Ingo; Sessler, Daniel I; Volk, Thomas; Kreuer, Sascha</p> <p>2017-10-25</p> <p>Propofol is a commonly used intravenous general anesthetic. Multi-capillary column (MCC) coupled Ion-mobility spectrometry (<span class="hlt">IMS</span>) can be used to quantify exhaled propofol, and thus estimate plasma drug concentration. Here, we present results of the calibration and analytical validation of a MCC/<span class="hlt">IMS</span> pre-market prototype for propofol quantification in exhaled air. Calibration with a reference gas generator yielded an R(2)≥0.99 with a linear array for the calibration curve from 0 to 20 ppbv. The limit of quantification was 0.3 ppbv and the limit of detection was 0.1 ppbv. The device is able to distinguish concentration differences >0.5 ppbv for the concentration range between 2 and 4 ppbv and >0.9 ppbv for the range between 28 and 30 ppbv. The imprecision at 20 ppbv is 11.3% whereas it is 3.5% at a concentration of 40 ppbv. The carry-over duration is 3min. The MCC/<span class="hlt">IMS</span> we tested provided online quantification of gaseous propofol over the clinically relevant range at measurement frequencies of one measurement each minute. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..1615243H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..1615243H"><span>Evaluation of Preproduction Hardware Components for <span class="hlt">IMS</span> Station Upgrades to Reduce Manufacturers Development Time</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hart, Darren; Pearce, Nathan; Starovoit, Yuri; Guralp, Cansun</p> <p>2014-05-01</p> <p>Since the Comprehensive Nuclear-Test-Ban Treaty was opened for signature in 1996, nearly 80% of the network has been certified as operational, and those stations are sending data to the International Data Centre (IDC) in Vienna. Several International Monitoring System (<span class="hlt">IMS</span>) monitoring facilities have been in operation for close to 15 years, and several certified stations are facing equipment obsolescence issues. The search for engineering solutions to replace obsolete hardware components is guided by two primary goals: 1) be compliant with <span class="hlt">IMS</span> minimum technical requirements and 2) be able to be integrated with the existing system. To reduce the development and verification time necessary to address obsolescence in equipment, the PTS has requested the preproduction testing of the recently revised Guralp CMG-DM24AM digitizer. Performing preproduction testing has helped in identifying issues, which Guralp Systems has resolved. In our poster, we will review the reasons for the digitizer updates, present results of the preproduction testing of the Guralp digitizer, and comment on the value this process has provided to the <span class="hlt">IMS</span> operation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.C41F..03H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.C41F..03H"><span>The Interactive Multi-sensor Snow and Ice Mapping System (<span class="hlt">IMS</span>) over the Last Two Decades.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Helfrich, S.; Key, J.; Clemente-Colón, P.; Robinson, D. A.; Estilow, T.; Kongoli, C.; Hall, D. K.</p> <p>2016-12-01</p> <p>The National Oceanic and Atmospheric Administration's National Environmental Satellite Data, and Information Service (NOAA/NESDIS) has been producing gridded snow and ice products from the <span class="hlt">IMS</span> since 1997. The product has underwent revision in the production environments versions three times, added and removed data sources, and had multiple staff and analysis processes since its inception. The first version was available only in a 24km estimate and was relient on geostationary and Special Sensor Microwave/Imager (SSM/I) imagery and products. The second version expanded the data sources to include higher resolution imagery and advanced satellites for the time. The most recent version has also expanded the product variables to include 4km snow depth, estimated ice thickness, ice concentration, and ranges for each of the additional variables. The <span class="hlt">IMS</span> Version 3 has also altered the production methodologies towards semi-automation. These changes over time are being made to meet user requirements for improved snow and ice characterization but are also carefully considering the impact changes have on the integrity of the any satellite-derived snow and ice records that apply the <span class="hlt">IMS</span> output. This presentation will discuss the alterations in the product over time and discuss the impacts this had on the product generation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3337085','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3337085"><span>Delineating Diseases by <span class="hlt">IMS</span>-MS Profiling of Serum N-linked Glycans</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Isailovic, Dragan; Plasencia, Manolo D.; Gaye, Maissa M.; Stokes, Sarah T.; Kurulugama, Ruwan. T.; Pungpapong, Vitara; Zhang, Min; Kyselova, Zuzana; Goldman, Radoslav; Mechref, Yehia; Novotny, Milos V.; Clemmer, David E.</p> <p>2012-01-01</p> <p>Altered branching and aberrant expression of N-linked glycans is known to be associated with disease states such as cancer. However, the complexity of determining such variations hinders the development of specific glycomic approaches for assessing disease states. Here, we examine a combination of ion mobility spectrometry (<span class="hlt">IMS</span>) and mass spectrometry (MS) measurements, with principal component analysis (PCA) for characterizing serum N-linked glycans from 81 individuals: 28 with cirrhosis of the liver; 25 with liver cancer; and 28 apparently healthy. Supervised PCA of combined ion-mobility profiles for several, to as many as ten different mass-to-charge ratios for glycan ions, improves the delineation of diseased states. This extends an earlier study [J.Proteome Res. 2008, 7, 1109-1117] of isomers associated with a single glycan (S1H5N4) in which PCA analysis of the <span class="hlt">IMS</span> profiles appeared to differentiate the liver cancer group from the other samples. Although performed on a limited number of test subjects, the combination of <span class="hlt">IMS</span>-MS for different combinations of ions and multivariate PCA analysis shows promise for characterizing disease states. PMID:22148953</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/81261','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/81261"><span>Correlation of <span class="hlt">I/M</span>240 and FTP emissions for Alternative Motor Fuels Act test vehicles</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Kelly, K.J.</p> <p>1994-10-01</p> <p>The National Remewable Energy Laboratory (NREL) is managing a series of light duty vehicle chasis dynamometer chasis tests on alternative fuel vehicles for the US Department of Energy (DOE). This testing program is part of a larger demonstration of alternative fuel vehicles that was mandated by the Alternative Motor Fuels Act of 1988 (AMFA). In Phase I of the AMFA emissions test program (AMFA I) 18 vehicles were tested by three laboratories. All the vehicles tested were 1991 model year. In Phase II of the program (AMFA II), the number of vehicles was increased to nearly 300, including M85 Dodge Spirits, E85 Chevrolet Luminas, and compressed natural gas Dodge passenger vans. Phase II testing includes a Federal Test Procedure (FTP) test, followed by two of the EPA`s Inspection/Maintenance (<span class="hlt">I/M</span>240) tests. It is concluded that the <span class="hlt">I/M</span>240 test is not an appropriate comparison to the FTP. Further the <span class="hlt">I/M</span> 240 test is not as reliable as the FTP in estimating the `real world` emissions of these relatively low emission vehicles. 7 refs., 10 figs., 8 tabs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24123401','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24123401"><span>A two-factor theory for concussion assessment using <span class="hlt">Im</span>PACT: memory and speed.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schatz, Philip; Maerlender, Arthur</p> <p>2013-12-01</p> <p>We present the initial validation of a two-factor structure of Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) using <span class="hlt">Im</span>PACT composite scores and document the reliability and validity of this factor structure. Factor analyses were conducted for baseline (N = 21,537) and post-concussion (N = 560) data, yielding "Memory" (Verbal and Visual) and "Speed" (Visual Motor Speed and Reaction Time) Factors; inclusion of Total Symptom Scores resulted in a third discrete factor. Speed and Memory z-scores were calculated, and test-retest reliability (using intra-class correlation coefficients) at 1 month (0.88/0.81), 1 year (0.85/0.75), and 2 years (0.76/0.74) were higher than published data using Composite scores. Speed and Memory scores yielded 89% sensitivity and 70% specificity, which was higher than composites (80%/62%) and comparable with subscales (91%/69%). This emergent two-factor structure has improved test-retest reliability with no loss of sensitivity/specificity and may improve understanding and interpretability of <span class="hlt">Im</span>PACT test results.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63880&keyword=Moon&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63880&keyword=Moon&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>EVALUATION OF CRYPTOSPORIDIUM OOCYST RECOVERY IN WATER BY EPA METHOD 1623 WITH A MODIFIED <span class="hlt">IMS</span> DISSOCIATION PROCEDURE.</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>EPA Methods 1622 and 1623 are the benchmarks for detection of Cryptosporidium spp. oocysts in water. 5-7 These methods consist of filtration, elution, purification by immunomagnetic separation (<span class="hlt">IMS</span>), and microscopic analysis after staining with a fluorescein isothiocyanate conju...</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_14 --> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.epa.gov/state-and-local-transportation/vehicle-emission-inspection-and-maintenance-im-provision-fixing','PESTICIDES'); return false;" href="https://www.epa.gov/state-and-local-transportation/vehicle-emission-inspection-and-maintenance-im-provision-fixing"><span>Vehicle Emission Inspection and Maintenance (<span class="hlt">I/M</span>) Provision in the Fixing America’s Surface Transportation (FAST) Act</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>This document is a memorandum regarding Vehicle Emission Inspection and Maintenance (<span class="hlt">I/M</span>) Provision in Fixing America's Surface Transportation (FAST) Act, which provides long-term funding certainty for surface transportation infrastructure planning</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-06-21/pdf/2010-14859.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-06-21/pdf/2010-14859.pdf"><span>75 FR 35088 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-06-21</p> <p>... Global Learning Consortium, Inc. Correction The document appearing on June 4, 2010, 75 FR 31816, should read as follows: The title INS Global Consortium, Inc. should read as <span class="hlt">IMS</span> Global Learning...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63880&keyword=moon&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=91083944&CFTOKEN=66683410','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63880&keyword=moon&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=91083944&CFTOKEN=66683410"><span>EVALUATION OF CRYPTOSPORIDIUM OOCYST RECOVERY IN WATER BY EPA METHOD 1623 WITH A MODIFIED <span class="hlt">IMS</span> DISSOCIATION PROCEDURE.</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>EPA Methods 1622 and 1623 are the benchmarks for detection of Cryptosporidium spp. oocysts in water. 5-7 These methods consist of filtration, elution, purification by immunomagnetic separation (<span class="hlt">IMS</span>), and microscopic analysis after staining with a fluorescein isothiocyanate conju...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=75195&keyword=restore+AND+river+AND+streams&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=90600261&CFTOKEN=69857982','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=75195&keyword=restore+AND+river+AND+streams&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=90600261&CFTOKEN=69857982"><span>EVALUATION OF AN ALTERNATIVE <span class="hlt">IMS</span> DISSOCIATION PROCEDURE FOR USE WITH METHOD 1622: DETECTION OF CRYPTOSPORIDIUM IN WATER</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>U.S. EPA Method 1623 is used to detect and quantify Cruptosporidum spp. oocysts in ater. The protocol consists of filtration, immunomagnetic separation (<span class="hlt">IMS</span>), staining with a fluorescent antibody, and microscopic analysis. Microscopic analysis includes detection by fluorescent ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=75195&keyword=parasite+AND+plants&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=75195&keyword=parasite+AND+plants&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>EVALUATION OF AN ALTERNATIVE <span class="hlt">IMS</span> DISSOCIATION PROCEDURE FOR USE WITH METHOD 1622: DETECTION OF CRYPTOSPORIDIUM IN WATER</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>U.S. EPA Method 1623 is used to detect and quantify Cruptosporidum spp. oocysts in ater. The protocol consists of filtration, immunomagnetic separation (<span class="hlt">IMS</span>), staining with a fluorescent antibody, and microscopic analysis. Microscopic analysis includes detection by fluorescent ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23364185','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23364185"><span>Use of ion-mobility mass spectrometry (<span class="hlt">IMS</span>-MS) to map polyoxometalate Keplerate clusters and their supramolecular assemblies.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Robbins, Philip J; Surman, Andrew J; Thiel, Johannes; Long, De-Liang; Cronin, Leroy</p> <p>2013-03-07</p> <p>We present the high-resolution (HRES-MS) and ion-mobility (<span class="hlt">IMS</span>-MS) mass spectrometry studies of icosahedral nanoscale polyoxometalate-based {L(30)}{(Mo)Mo(5)} Keplerate clusters, and demonstrate the use of <span class="hlt">IMS</span>-MS to resolve and map intact nanoclusters, and its potential for the discovery of new structures, in this case the first gas phase observation of 'proto-clustering' of higher order Keplerate supramolecular aggregates.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AMT.....9.3245K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AMT.....9.3245K"><span>Ion mobility spectrometry-mass spectrometry (<span class="hlt">IMS</span>-MS) for on- and offline analysis of atmospheric gas and aerosol species</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krechmer, Jordan E.; Groessl, Michael; Zhang, Xuan; Junninen, Heikki; Massoli, Paola; Lambe, Andrew T.; Kimmel, Joel R.; Cubison, Michael J.; Graf, Stephan; Lin, Ying-Hsuan; Budisulistiorini, Sri H.; Zhang, Haofei; Surratt, Jason D.; Knochenmuss, Richard; Jayne, John T.; Worsnop, Douglas R.; Jimenez, Jose-Luis; Canagaratna, Manjula R.</p> <p>2016-07-01</p> <p>Measurement techniques that provide molecular-level information are needed to elucidate the multiphase processes that produce secondary organic aerosol (SOA) species in the atmosphere. Here we demonstrate the application of ion mobility spectrometry-mass spectrometry (<span class="hlt">IMS</span>-MS) to the simultaneous characterization of the elemental composition and molecular structures of organic species in the gas and particulate phases. Molecular ions of gas-phase organic species are measured online with <span class="hlt">IMS</span>-MS after ionization with a custom-built nitrate chemical ionization (CI) source. This CI-<span class="hlt">IMS</span>-MS technique is used to obtain time-resolved measurements (5 min) of highly oxidized organic molecules during the 2013 Southern Oxidant and Aerosol Study (SOAS) ambient field campaign in the forested SE US. The ambient <span class="hlt">IMS</span>-MS signals are consistent with laboratory <span class="hlt">IMS</span>-MS spectra obtained from single-component carboxylic acids and multicomponent mixtures of isoprene and monoterpene oxidation products. Mass-mobility correlations in the 2-D <span class="hlt">IMS</span>-MS space provide a means of identifying ions with similar molecular structures within complex mass spectra and are used to separate and identify monoterpene oxidation products in the ambient data that are produced from different chemical pathways. Water-soluble organic carbon (WSOC) constituents of fine aerosol particles that are not resolvable with standard analytical separation methods, such as liquid chromatography (LC), are shown to be separable with <span class="hlt">IMS</span>-MS coupled to an electrospray ionization (ESI) source. The capability to use ion mobility to differentiate between isomers is demonstrated for organosulfates derived from the reactive uptake of isomers of isoprene epoxydiols (IEPOX) onto wet acidic sulfate aerosol. Controlled fragmentation of precursor ions by collisionally induced dissociation (CID) in the transfer region between the <span class="hlt">IMS</span> and the MS is used to validate MS peak assignments, elucidate structures of oligomers, and confirm the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/962848','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/962848"><span><span class="hlt">Im</span>SET 3.1: Impact of Sector Energy Technologies Model Description and User's Guide</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Scott, Michael J.; Livingston, Olga V.; Balducci, Patrick J.; Roop, Joseph M.; Schultz, Robert W.</p> <p>2009-05-22</p> <p>This 3.1 version of the Impact of Sector Energy Technologies (<span class="hlt">Im</span>SET) model represents the next generation of the previously-built <span class="hlt">Im</span>SET model (<span class="hlt">Im</span>SET 2.0) that was developed in 2005 to estimate the macroeconomic impacts of energy-efficient technology in buildings. In particular, a special-purpose version of the Benchmark National Input-Output (I-O) model was designed specifically to estimate the national employment and income effects of the deployment of Office of Energy Efficiency and Renewable Energy (EERE)–developed energy-saving technologies. In comparison with the previous versions of the model, this version features the use of the U.S. Bureau of Economic Analysis 2002 national input-output table and the central processing code has been moved from the FORTRAN legacy operating environment to a modern C++ code. <span class="hlt">Im</span>SET is also easier to use than extant macroeconomic simulation models and incorporates information developed by each of the EERE offices as part of the requirements of the Government Performance and Results Act. While it does not include the ability to model certain dynamic features of markets for labor and other factors of production featured in the more complex models, for most purposes these excluded features are not critical. The analysis is credible as long as the assumption is made that relative prices in the economy would not be substantially affected by energy efficiency investments. In most cases, the expected scale of these investments is small enough that neither labor markets nor production cost relationships should seriously affect national prices as the investments are made. The exact timing of impacts on gross product, employment, and national wage income from energy efficiency investments is not well-enough understood that much special insight can be gained from the additional dynamic sophistication of a macroeconomic simulation model. Thus, we believe that this version of <span class="hlt">Im</span>SET is a cost-effective solution to estimating the economic</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009PhDT.......101W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009PhDT.......101W"><span>Developing integrated TOF-SIMS/MALDI <span class="hlt">IMS</span> system in studying biological systems</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wu, Ligang</p> <p></p> <p>Using imaging mass spectrometry (<span class="hlt">IMS</span>) techniques (including TOF-SIMS and MALDI <span class="hlt">IMS</span>) to study biological systems is a relatively new concept and quickly gained popularity in recent years. Imaging mass spectrometry is a discovery technology that utilizes a focused ion beam or laser beam to desorb ions from sample surface. By detecting the desorbed ions, the chemical distributions and biological changes of a sample surface can be analyzed. These techniques offer a new analytical imaging approach to investigate biological processes at the cellular and tissue level. In this research, a novel integrated TOF-SIMS/MALDI <span class="hlt">IMS</span> system as well as <span class="hlt">IMS</span> based biological-sample-preparation techniques and data-reduction methods are developed. We then demonstrate the power of these techniques in studying different biological systems, including monosaccharides isomers, human breast cancer cell lines, mouse embryo tissues and mouse kidney sections. Using TOF-SIMS and statistical analysis methods, seven monosaccharide isomers are fully differentiated by analyzing their characteristic spectral pattern. In addition, a deep understanding of the fragmentation pathway of these isomers under ion bombardment is gained. In an application of TOF-SIMS to the differentiation of three human breast cancer cell lines, MCF-7, T47D, and MDA-MB-231, we show that principal component analysis (PCA) data reduction of TOF-SIMS spectra can differentiate cellular compartments (cytosol, nuclear and particulate) within the cell types, as well as homogenates from among the three cell lines. In a tissue-specific application, we extend the analytical capabilities of TOF-SIMS and PCA by imaging and differentiating Formalin-fixed paraffin-embedded (FFPE) mouse embryo tissues. We demonstrate reproducible differentiation of six tissue types based on the remaining small molecules after paraffin-embedding and the fragments of the cellular proteins. In a unique study of fresh frozen mouse kidney tissues, both TOF</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..12.9200D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..12.9200D"><span>A study of volcanic eruption characteristics using infrasound data recorded on the global <span class="hlt">IMS</span> network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Dabrowa, Amy; Green, David; Phillips, Jeremy; Rust, Alison</p> <p>2010-05-01</p> <p>Explosive volcanic eruptions have the capability to generate sound waves with infrasonic frequencies (<20Hz). As such waves can propagate over distances of thousands of kilometres within the atmosphere, they present an opportunity to remotely monitor volcanic eruptions and potentially constrain eruptive characteristics. Though most volcanoes in sensitive areas of the world are monitored individually, many volcanoes in remote locations are not monitored directly but can still pose a threat, especially to aviation. The growing International Monitoring System (<span class="hlt">IMS</span>) network of infrasound stations provides an opportunity to monitor these remote volcanoes. Currently comprising of 43 arrays, the network is designed to achieve global coverage for surface explosions equivalent to a few hundred tonnes of chemical explosive. In recent years work has been published on the detection of specific volcanic eruptions at <span class="hlt">IMS</span> stations, primarily at regional ranges (< 1000 km from volcano to receiver). In contrast, work presented here looks to create a catalogue of volcanic eruptions that have been detected at <span class="hlt">IMS</span> stations, with the aim of assessing the capability of the <span class="hlt">IMS</span> network for use in global volcano monitoring. At this time 40 eruptive events at 19 volcanoes have been investigated from the period 2004 - 2009; however the work is on-going and it is planned to extend this catalogue. In total we document 61 individual detections that have been made on the <span class="hlt">IMS</span> network. These range from Strombolian activity at Mount Erebus (Antarctica) recorded at a range of 25 km distance, to the Plinian eruption of Manam Volcano (Papua New Guinea) recorded at ranges of over 10,000 km distance. The observed signal frequencies for different eruptions range from less than 0.01 Hz to greater than 5 Hz, and in general, lower frequencies are generated by the larger eruptions. We provide examples of analyses for eruptions recorded at multiple stations (e.g., Manam, October 2004; Kasatochi, August 2008</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24812853','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24812853"><span>[Development of an <span class="hlt">IMS</span>-qPCR method for detection of Cryptosporidium parvum in water].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gao, Shan-Shan; Wu, Shao-Qiang; Luo, Jing; Wang, Cheng-Min; Zhang, Min; Zhao, Bao-Hua; He, Hong-Xuan</p> <p>2013-06-01</p> <p>To develop a detection method for Cryptosporidium parvum oocysts from water samples, which combined immunomagnetic separation (<span class="hlt">IMS</span>) with Taqman real-time PCR (qPCR). Conditions of separation and enrichment of <span class="hlt">IMS</span> method by using specific streptavidin magnetic beads coated with monoclonal antibodies Cp23 directed against C. parvum oocysts were optimized. Special primers of PCR and Taqman probes were designed referring to the 18S rDNA gene of C. parvum (GenBank Accession No. AB513881.1). The conserved genes were amplified from genomic DNA of C.parvum, and then cloned into Peasy-T1 vector. Tenfold dilutions of positive plasmids (10(4)-10(8) copy/microl) were used to construct a standard curves by Taqman qPCR. The specificity of the assay was determined using genomic DNA of C. baileyi, Toxoplasma gondii, C. canis and Escherichia coli. The sensitivity of this assay was evaluated by analyzing 10-fold serially dilutions of plasmids ranging from 10(0) to 10(8) copy/microl. Both <span class="hlt">IMS</span>-qPCR assay and indirect immunofluorescent-antibody assay (IFA) were applied to detect 50 water samples collected from the dairy cattle farms in Hebei. The optimal incubation concentration and time of antibody Cp23 were 20 ng/ml and 30 min, respectively, and the catching time was 30 min, the recovery rate was more than 95%. PCR product was 272 bp, and identified by restriction enzyme digestion and nucleotide sequencing. There was a good linear relationship between the standard plasmids and Ct value (correlation r2 = 0.996 1) of the Taqman qPCR. No cross-reactivity was observed with C. baileyi, T. gondii, C. canis and E. coli. The sensitivity of C. parvum-specific assay was 10 copy/microl. Compared with IFA as golden standard method, the specificity and sensitivity of <span class="hlt">IMS</span>-qPCR for 50 water samples was 100%(18/18) and 93.8% (30/32), respectively. The <span class="hlt">IMS</span>-qPCR assay can be used to specifically detect C. parvum oocysts in water samples.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2793296','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2793296"><span>Mammalian pre-mRNA 3′ End Processing Factor CF <span class="hlt">Im</span>68 Functions in mRNA Export</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ruepp, Marc-David; Aringhieri, Chiara; Vivarelli, Silvia; Cardinale, Stefano; Paro, Simona; Schümperli, Daniel</p> <p>2009-01-01</p> <p>Export of mRNA from the nucleus is linked to proper processing and packaging into ribonucleoprotein complexes. Although several observations indicate a coupling between mRNA 3′ end formation and export, it is not known how these two processes are mechanistically connected. Here, we show that a subunit of the mammalian pre-mRNA 3′ end processing complex, CF <span class="hlt">Im</span>68, stimulates mRNA export. CF <span class="hlt">Im</span>68 shuttles between the nucleus and the cytoplasm in a transcription-dependent manner and interacts with the mRNA export receptor NXF1/TAP. Consistent with the idea that CF <span class="hlt">Im</span>68 may act as a novel adaptor for NXF1/TAP, we show that CF <span class="hlt">Im</span>68 promotes the export of a reporter mRNA as well as of endogenous mRNAs, whereas silencing by RNAi results in the accumulation of mRNAs in the nucleus. Moreover, CF <span class="hlt">Im</span>68 associates with 80S ribosomes but not polysomes, suggesting that it is part of the mRNP that is remodeled in the cytoplasm during the initial stages of translation. These results reveal a novel function for the pre-mRNA 3′ end processing factor CF <span class="hlt">Im</span>68 in mRNA export. PMID:19864460</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27607035','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27607035"><span>Gerbstoffe aus Potentilla officinalis wirken entzündungshemmend <span class="hlt">im</span> UV-Erythem-Test und bei Anwendung auf atopischer Haut.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hoffmann, Julia; Wölfle, Ute; Schempp, Christoph M; Casetti, Federica</p> <p>2016-09-01</p> <p>Das Rhizom von Potentilla officinalis (PO) ist reich an Gerbstoffen und wird traditionell zur äußerlichen Behandlung von Entzündungen der Haut und der Schleimhäute verwendet. Ziel der vorliegenden Arbeit war die Bestätigung der antiinflammatorischen Eigenschaften von PO mittels eines UV-Erythem-Tests und einer klinischen Anwendungsstudie bei atopischer Haut. Die antiinflammatorische Wirkung eines PO-Extrakts (standardisiert auf 2 % Trockensubstanz) wurde in einer prospektiven, randomisierten, placebokontrollierten Doppelblindstudie mit 40 gesunden Erwachsenen <span class="hlt">im</span> UV-Erythem-Test <span class="hlt">im</span> Vergleich zu 1 % Hydrocortisonacetat untersucht. <span class="hlt">Im</span> Rahmen einer prospektiven nicht kontrollierten Studie wurde die Wirkung und Verträglichkeit der 2 % PO-Creme an zwölf Erwachsenen und zwölf Kindern mit atopischer Haut nach Anwendung über zwei Wochen in einem definierten Testareal anhand eines Teil-SCORAD untersucht. Zusätzlich wurde die Beeinflussung der Hautrötung <span class="hlt">im</span> Testareal photometrisch gemessen. <span class="hlt">Im</span> UV-Erythem-Test zeigte die PO-Creme eine signifikante Reduktion des Erythemindex <span class="hlt">im</span> Vergleich zum Vehikel. Die antiinflammatorische Wirkung des Verums entsprach der der 1 % Hydrocortisonacetat-Creme. Die klinische Studie bei Atopikern zeigte eine signifikante Abnahme des Teil-SCORAD und des Erythems <span class="hlt">im</span> Testareal. Es wurden keine Unverträglichkeitsreaktionen beobachtet. PO als 2%ige Zubereitung besitzt entzündungshemmende Eigenschaften und ist wirksam und gut verträglich auf atopischer Haut. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/958635','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/958635"><span>Solvation of Ucl (6)**2- Anionic Complex By Mebu (3) N+, Bume (2) <span class="hlt">Im</span>+, And Bumeim+ Cations</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Bosse, E.; Auwer, C.Den; Berthon, C.; Guilbaud, P.; Grigoriev, M.S.; Nikitenko, S.; Naour, C.Le; Cannes, C.; Moisy, P.</p> <p>2009-05-11</p> <p>The complexes [MeBu{sub 3}N]{sub 2}[UCl{sub 6}] and [BuMe{sub 2}<span class="hlt">Im</span>]{sub 2}[UCl{sub 6}] were characterized in the solid state and in solution of [MeBu{sub 3}N][Tf{sub 2}N], [BuMe{sub 2}<span class="hlt">Im</span>][Tf{sub 2}N], and [BuMe<span class="hlt">Im</span>][Tf{sub 2}N] room-temperature ionic liquids using single-crystal XRD, EXAFS, electrochemistry, UV-visible absorption spectroscopy, and NMR. In the solid state and in solution, the existence of hydrogen bonding between the UCl{sub 6}{sup 2-} complex and the ionic liquid cations was revealed by these techniques. The MeBu{sub 3}N{sup +} cation interacts with UCl{sub 6}{sup 2-} via the protons on the {alpha}-carbon atoms of nitrogen. The protons of the imidazolium ring account for the interaction between the BuMe{sub 2}<span class="hlt">Im</span>{sup +} cation and the UCl{sub 6}{sup 2-} anion. For the BuMe<span class="hlt">Im</span>{sup +} cation the major interaction was confirmed between the most acidic proton on C(2) and the chlorides of UCl{sub 6}{sup 2-}. The experimental results also show that the intensity of the interaction between the UCl{sub 6}{sup 2-} anion and the cation varies with the ionic liquid cation in the following order: MeBu{sub 3}N{sup +} {approx} BuMe{sub 2}<span class="hlt">Im</span>{sup +} << BuMe<span class="hlt">Im</span>{sup +}.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002AGUFM.S71A1057E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002AGUFM.S71A1057E"><span>Low Noise Results From <span class="hlt">IMS</span> Site Surveys: A Preliminary New High-Frequency Low Noise Model</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ebeling, C.; Astiz, L.; Starovoit, Y.; Tavener, N.; Perez, G.; Given, H. K.; Barrientos, S.; Yamamoto, M.; Hfaiedh, M.; Stewart, R.; Estabrook, C.</p> <p>2002-12-01</p> <p>Since the establishment of the Provisional Technical Secretariat (PTS) of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) Organization, a vigorous seismic site survey program has been carried out to identify locations as necessary for International Monitoring System (<span class="hlt">IMS</span>) primary and auxiliary seismic stations listed in Annex 1 to the Protocol to the CTBT. The <span class="hlt">IMS</span> Seismic Section maintains for this purpose a small pool of seismic equipment comprised of Guralp CMG-3T and CMG-3ESP and Streckeisen STS-2 broadband seismometers, and Reftek and Guralp acquisition systems. Seismic site surveys are carried out by conducting continuous measurements of ground motion at temporary installations for approximately five to seven days. Seismometer installation methods, which depend on instrument type and on local conditions, range from placement within small cement-floored subsurface vaults to near-surface burial. Data are sampled at 40 Hz. Seismic noise levels are evaluated through the analysis of power spectral density distributions. Eleven 10.5-minute-long representative de-trended and mean-removed segments each of daytime and night-time data are chosen randomly, but reviewed to avoid event contamination. Fast Fourier Transforms are calculated for the five windows in each of these segments generated using a 50% overlap for Hanning-tapered sections ~200 s long. Instrument responses are removed. To date, 20 site surveys for primary and auxiliary stations have been carried out by the <span class="hlt">IMS</span>. The sites surveyed represent a variety of physical and geological environments on most continents. The lowest high frequency (>1.4 Hz) noise levels at five sites with igneous or metamorphic geologies were as much as 6 dB below the USGS New Low Noise Model (NLNM) developed by Peterson (1993). These sites were in Oman (local geology consisting of Ordovician metasediments), Egypt (Precambrian granite), Niger (early Proterozoic tonalite and granodiorite), Saudi Arabia (Precambian metasediments), and</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22261989','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22261989"><span>Alkaline earth imidazolate coordination polymers by solvent free melt synthesis as potential host lattices for rare earth photoluminescence: (x)(∞)[AE(<span class="hlt">Im</span>)2(<span class="hlt">Im</span>H)(2-3)], Mg, Ca, Sr, Ba, x = 1-2.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zurawski, Alexander; Rybak, J-Christoph; Meyer, Larissa V; Matthes, Philipp R; Stepanenko, Vladimir; Dannenbauer, Nicole; Würthner, Frank; Müller-Buschbaum, Klaus</p> <p>2012-04-14</p> <p>The series of alkaline earth elements magnesium, calcium, strontium and barium yields single crystalline imidazolate coordination polymers by reactions of the metals with a melt of 1H-imidazole: (1)(∞)[Mg(<span class="hlt">Im</span>)(2)(<span class="hlt">Im</span>H)(3)] (1), (2)(∞)[AE(<span class="hlt">Im</span>)(2)(<span class="hlt">Im</span>H)(2)], AE = Ca (2), Sr (3), and (1)(∞)[Ba(<span class="hlt">Im</span>)(2)(<span class="hlt">Im</span>H)(2)] (4). No additional solvents were used for the reactions. Co-doping experiments by addition of the rare earth elements cerium, europium and terbium were carried out. They indicate (2)(∞)[Sr(<span class="hlt">Im</span>)(2)(<span class="hlt">Im</span>H)(2)] as a possible host lattice for cerium(III) photoluminescence showing a blue emission and thus a novel blue emitting hybrid material phosphor 3:Ce(3+). Co-doping with europium and terbium is also possible but resulted in formation of (3)(∞)[Sr(<span class="hlt">Im</span>)(2)]:Ln, Ln = Eu and Tb (5), with both exhibiting green emission of either Eu(2+) or Tb(3+). The other alkaline earth elements do not show acceptance of the rare earth ions investigated and a different structural chemistry. For magnesium and barium one-dimensional strand structures are observed whereas calcium and strontium give two-dimensional network structures. Combined with an increase of the ionic radii of AE(2+) the coordinative demand is also increasing from Mg(2+) to Ba(2+), reflected by four different crystal structures for the four elements Mg, Ca, Sr, Ba in 1-4. Different linkages of the imidazolate ligands result in a change from complete σ-N coordination in 1 to additional η(5)-π coordination in 4. The success of co-doping with different lanthanide ions is based on a match in the chemical behaviour and cationic radii. The use of strontium for host lattices with imidazole is a rare example in coordination chemistry of co-doping with small amounts of luminescence centers and successfully reduces the amount of high price rare earth elements in hybrid materials while maintaining the properties. All compounds are examples of pure N-coordinated coordination polymers of the alkaline earth metals and were</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010bukm.book...79H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010bukm.book...79H"><span>Praktikerporträts</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Herber, Kamilla; Kramer, Regine; Voigt, Bernd</p> <p></p> <p>Wie vielfältig die beruflichen Möglichkeiten von MINT-Absolventen sind, zeigen die nachfolgenden Praktikerporträts. Aus sämtlichen Branchen und in den verschiedensten Positionen berichten die Praktiker über <span class="hlt">ihr</span> Studium, die unterschiedlichsten Karrierewege und <span class="hlt">ihre</span> Erfahrungen <span class="hlt">im</span> Berufsleben.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4442642','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4442642"><span>MALDI FTICR <span class="hlt">IMS</span> of intact proteins: Using mass accuracy to link protein images with proteomics data</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Spraggins, Jeffrey M.; Rizzo, David G.; Moore, Jessica L.; Rose, Kristie L.; Hammer, Neal D.; Skaar, Eric P.; Caprioli, Richard M.</p> <p>2015-01-01</p> <p>MALDI imaging mass spectrometry is a highly sensitive and selective tool used to visualize biomolecules in tissue. However, identification of detected proteins remains a difficult task. Indirect identifications strategies have been limited by insufficient mass accuracy to confidently link ion images to proteomics data. Here we demonstrate the capabilities of MALDI FTICR MS for imaging intact proteins. MALDI FTICR <span class="hlt">IMS</span> provides an unprecedented combination of mass resolving power (∼75,000 at m/z 5,000) and accuracy (<5 ppm) for proteins up to ∼12 kDa enabling identification based on correlation with LC-MS/MS proteomics data. Analysis of rat brain tissue was performed as a proof-of-concept highlighting the capabilities of this approach by imaging and identifying a number of proteins including N-terminally acetylated Thymosin β4 (m/z 4,963.502, 0.6 ppm) and ATP Synthase subunit ε (m/z 5,636.074, −2.3 ppm). MALDI FTICR <span class="hlt">IMS</span> was also used to differentiate a series of oxidation products of S100A8 (m/z 10,164.03, −2.1 ppm), a subunit of the heterodimer calprotectin, in kidney tissue from mice infected with Staphylococcus aureus. S100A8 – M37O/C42O3 (m/z 10228.00, −2.6 ppm) was found to co-localize with bactierial microcolonies at the center of infectious foci. The ability of MALDI FTICR <span class="hlt">IMS</span> to distinguish S100A8 modifications is critical to understanding calprotectin’s roll in nutritional immunity. PMID:25904064</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JASMS..26..974S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JASMS..26..974S"><span>MALDI FTICR <span class="hlt">IMS</span> of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Spraggins, Jeffrey M.; Rizzo, David G.; Moore, Jessica L.; Rose, Kristie L.; Hammer, Neal D.; Skaar, Eric P.; Caprioli, Richard M.</p> <p>2015-06-01</p> <p>MALDI imaging mass spectrometry is a highly sensitive and selective tool used to visualize biomolecules in tissue. However, identification of detected proteins remains a difficult task. Indirect identification strategies have been limited by insufficient mass accuracy to confidently link ion images to proteomics data. Here, we demonstrate the capabilities of MALDI FTICR MS for imaging intact proteins. MALDI FTICR <span class="hlt">IMS</span> provides an unprecedented combination of mass resolving power (~75,000 at m/z 5000) and accuracy (<5ppm) for proteins up to ~12kDa, enabling identification based on correlation with LC-MS/MS proteomics data. Analysis of rat brain tissue was performed as a proof-of-concept highlighting the capabilities of this approach by imaging and identifying a number of proteins including N-terminally acetylated thymosin β4 ( m/z 4,963.502, 0.6ppm) and ATP synthase subunit ɛ ( m/z 5,636.074, -2.3ppm). MALDI FTICR <span class="hlt">IMS</span> was also used to differentiate a series of oxidation products of S100A8 ( m/z 10,164.03, -2.1ppm), a subunit of the heterodimer calprotectin, in kidney tissue from mice infected with Staphylococcus aureus. S100A8 - M37O/C42O3 ( m/z 10228.00, -2.6ppm) was found to co-localize with bacterial microcolonies at the center of infectious foci. The ability of MALDI FTICR <span class="hlt">IMS</span> to distinguish S100A8 modifications is critical to understanding calprotectin's roll in nutritional immunity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4128893','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4128893"><span>Drivers of Costs Associated with Reperfusion Therapy in Acute Stroke: The <span class="hlt">IMS</span> III Trial</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Simpson, Kit N.; Simpson, Annie N.; Mauldin, Patrick D.; Hill, Michael D; Yeatts, Sharon D.; Spilker, Judith A.; Foster, Lydia D.; Khatri, Pooja; Martin, Renee; Jauch, Edward C.; Kleindorfer, Dawn; Palesch, Yuko Y.; Broderick, Joseph P.</p> <p>2014-01-01</p> <p>Background and Purpose The <span class="hlt">IMS</span> III study tested the effect of IV t-PA alone as compared to IV t-PA followed by endovascular therapy and collected cost data to assess the economic implications of the two therapies. This report describes the factors affecting the costs of the initial hospitalization for acute stroke subjects from the US. Methods Prospective cost analysis of US subjects treated with IV t-PA alone or IV t-PA followed by endovascular therapy in the <span class="hlt">IMS</span> III trial. Results compared to expected Medicare payments. Results The adjusted cost of a stroke admission in the study was $35,130 for subjects treated with endovascular therapy following IV t-PA treatment and $25,630 for subjects treated with IV t-PA alone (p<0.0001). Significant factors related to costs included treatment group, baseline NIH Stroke Scale, time from stroke onset to IV t-PA, age, stroke location, and comorbid diabetes. The mean cost for subjects who had routine use of general anesthesia as part of endovascular therapy was $46,444 as compared to $30,350 for those who did not have general anesthesia. The costs of embolectomy for <span class="hlt">IMS</span> III subjects and patients from the NIS cohort exceeded the Medicare DRG payment in more than 75% of patients. Conclusion Minimizing the time to start of IV t-PA and decreasing the use of routine general anesthesia, may improve the cost-effectiveness of medical and endovascular therapy for acute stroke. PMID:24876261</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_15 --> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26072759','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26072759"><span>Mitigation of timing offset effect in <span class="hlt">IM</span>/DD based OFDMA-PON uplink multiple access.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jung, Sun-Young; Jung, Sang-Min; Park, Hyoung-Joon; Han, Sang-Kook</p> <p>2015-06-01</p> <p>In orthogonal frequency division multiple access based passive optical network (OFDMA-PON) uplink, synchronization between optical network units (ONUs) is very important to maintain orthogonality. The synchronization among uplink signals is considered as one of the main challenges in OFDMA-PON due to optical path difference. In this paper, the performance degradation according to timing offset between ONUs is experimentally analyzed. And we propose and demonstrate timing offset effect reduction in asynchronous multiple access by using CP extension and filter bank based multicarrier (FBMC) system in intensity modulation/direct detection (<span class="hlt">IM</span>/DD) based OFDMA-PON uplink transmission.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1996BAAA...40Q..46O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1996BAAA...40Q..46O"><span>Fotometría de <span class="hlt">im</span>ágenes CCD insuficientemente muestreadas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ostrov, P. G.</p> <p></p> <p>Se enfrenta el problema de la fotometría de <span class="hlt">im</span>ágenes CCD con una escala inadecuada (fwhm menor o igual que el tamaño de un pixel) y psf fuertemente variable con la posición. Se analiza, en particular, la aplicabilidad de una táctica propuesta por Massey, consistente en eliminar las vecinas débiles (utilizando una psf rudimentaria) para luego efectuar una fotometría de apertura sobre las estrellas brillantes. Se determina, mediante experimentos numéricos, la precisión alcanzada mediante esta técnica.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026846','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026846"><span>The effects of CO2 on the negative reactant ions of <span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Spangler, Glenn E.</p> <p>1995-01-01</p> <p>In the presence of CO2, the negative reactant ions of ion mobility spectrometry (<span class="hlt">IMS</span>) are ion clusters of CO4(-) and CO3(-). Methyl salicylate is ionized by the CO4(-)(H2O(n))(N2(m)) reactant ions, but not by the CO3(-)(H2O(n))(N2(m)) reactant ions. While the CO4(-) ions are formed by direct association, the CO3(-) ions require additional energy to be formed. The additional energy is provided by either excited neutral gas molecules in a metastable state or UV (ultraviolet) radiation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19770003173','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19770003173"><span>Daily summary for <span class="hlt">IMS</span> high-altitude satellites, days 1-181 1977</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1976-01-01</p> <p>A description of the orbital positions is provided for a number of high altitude satellites capable of making magnetospheric measurements in the first half of 1977 as part of the International Magnetospheric Study (<span class="hlt">IMS</span>). Six artificial satellites -- Vela 5B, IMP-H, IMP-J, Solrad 11A, Solrad 11B, and Hawkeye 1 -- have been chosen along with the moon. The daily position summary of the satellites includes data tables which provide the crossing times of the bow shock and magnetopause, as well as the entry and exit times from the cusp, the high latitude tail, the midlatitude tail, and the neutral sheet region.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19760008136','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19760008136"><span><span class="hlt">IMS</span>/Satellite Situation Center report. Predicted orbit plots for Vela 5B, 1976</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1975-01-01</p> <p>Predicted orbit plots for the Vela 5B satellite are presented for the time period January-December 1976. This satellite has been identified as an important possible contributor to the International Magnetospheric Study (<span class="hlt">IMS</span>) project. The predicted orbit plots are shown in three projections. The time period covered by each set of projections is 4 days 16 hours, corresponding approximately to the period of Vela 5B. The three coordinate systems used are the Geocentric Solar Ecliptic system (GSE), the Geocentric Solar Magnetospheric system (GSM), and the Solar Magnetic system (SM).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA221790','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA221790"><span>Fatigue Behavior of P/M 7091 and <span class="hlt">I/M</span> 7475 Aluminum Alloys</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1989-10-01</p> <p>properties, fatigue behavior , microstruc - ture, and fractograph. TENSILE PROPERTIES Tensile test results of P/M 7091-T7E69 and l/M 7475-T7351...REPORT NO. NADC-89090-60 •1! <-.< (_ FATIGUE BEHAVIOR OF P/M 7091 AND l/M 7475 ALUMINUM ALLOYS A PA -221 79® ( Eun U. Lee . Air Vehicle and... Behavior of P/M 7091 and <span class="hlt">I/M</span> 7475 Aluminum Alloys 12. PERSONAL AUTHOR(S) Eun U. Lee 13a. TYPE OF REPORT Phase 13b. TIME COVERED FROM TO 14. DATE</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JASMS..26.1092Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JASMS..26.1092Z"><span>Glycopeptide Site Heterogeneity and Structural Diversity Determined by Combined Lectin Affinity Chromatography/<span class="hlt">IMS</span>/CID/MS Techniques</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zhu, Feifei; Trinidad, Jonathan C.; Clemmer, David E.</p> <p>2015-07-01</p> <p>Glycopeptides from a tryptic digest of chicken ovomucoid were enriched using a simplified lectin affinity chromatography (LAC) platform, and characterized by high-resolution mass spectrometry (MS) as well as ion mobility spectrometry (<span class="hlt">IMS</span>)-MS. The LAC platform effectively enriched the glycoproteome, from which a total of 117 glycopeptides containing 27 glycan forms were identified for this protein. <span class="hlt">IMS</span>-MS analysis revealed a high degree of glycopeptide site heterogeneity. Comparison of the <span class="hlt">IMS</span> distributions of the glycopeptides from different charge states reveals that higher charge states allow more structures to be resolved. Presumably the repulsive interactions between charged sites lead to more open configurations, which are more readily separated compared with the more compact, lower charge state forms of the same groups of species. Combining <span class="hlt">IMS</span> with collision induced dissociation (CID) made it possible to determine the presence of isomeric glycans and to reconstruct their <span class="hlt">IMS</span> profiles. This study illustrates a workflow involving hybrid techniques for determining glycopeptide site heterogeneity and evaluating structural diversity of glycans and glycopeptides.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009mmos.book..280B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009mmos.book..280B"><span>An <span class="hlt">IMS</span>-Based Middleware Solution for Energy-Efficient and Cost-Effective Mobile Multimedia Services</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bellavista, Paolo; Corradi, Antonio; Foschini, Luca</p> <p></p> <p>Mobile multimedia services have recently become of extreme industrial relevance due to the advances in both wireless client devices and multimedia communications. That has motivated important standardization efforts, such as the IP Multimedia Subsystem (<span class="hlt">IMS</span>) to support session control, mobility, and interoperability in all-IP next generation networks. Notwithstanding the central role of <span class="hlt">IMS</span> in novel mobile multimedia, the potential of <span class="hlt">IMS</span>-based service composition for the development of new classes of ready-to-use, energy-efficient, and cost-effective services is still widely unexplored. The paper proposes an original solution for the dynamic and standard-compliant redirection of incoming voice calls towards WiFi-equipped smart phones. The primary design guideline is to reduce energy consumption and service costs for the final user by automatically switching from the 3G to the WiFi infrastructure whenever possible. The proposal is fully compliant with the <span class="hlt">IMS</span> standard and exploits the recently released <span class="hlt">IMS</span> presence service to update device location and current communication opportunities. The reported experimental results point out that our solution, in a simple way and with full compliance with state-of-the-art industrially-accepted standards, can significantly increase battery lifetime without negative effects on call initiation delay.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012JMoSt1019..183Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012JMoSt1019..183Z"><span>Synthesis, characterization, DNA-binding and cytotoxic properties of Ru(II) complexes: [Ru(Me<span class="hlt">Im</span>)4L]2+ (Me<span class="hlt">Im</span> = 1-methylimidazole, L = phen, ip and pip)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zeng, Leli; Xiao, Yue; Liu, Jing; Tan, Lifeng</p> <p>2012-07-01</p> <p>Three new ruthenium(II) complexes, [Ru(Me<span class="hlt">Im</span>)4phen]2+ (1), [Ru(Me<span class="hlt">Im</span>)4ip]2+ (2) and [Ru(Me<span class="hlt">Im</span>)4pip]2+ (3), have been synthesized and characterized. The binding properties of the three complexes towards calf-thymus DNA were investigated by different spectrophotometric methods and viscosity measurements. In addition, the cytotoxicity of these complexes has been evaluated by MTT method and Giemsa staining experiment. The main results reveal that the plane area and hydrophobicity of intercalative ligands have a significant effect on the DNA-binding behaviors and the IC50 value of complex 2 against MCF-7 cells is close to that of cis-Pt(NH3)2Cl2.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AIPC.1864b0170C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AIPC.1864b0170C"><span>Frequent statistics of link-layer bit stream data based on AC-<span class="hlt">IM</span> algorithm</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cao, Chenghong; Lei, Yingke; Xu, Yiming</p> <p>2017-08-01</p> <p>At present, there are many relevant researches on data processing using classical pattern matching and its improved algorithm, but few researches on statistical data of link-layer bit stream. This paper adopts a frequent statistical method of link-layer bit stream data based on AC-<span class="hlt">IM</span> algorithm for classical multi-pattern matching algorithms such as AC algorithm has high computational complexity, low efficiency and it cannot be applied to binary bit stream data. The method's maximum jump distance of the mode tree is length of the shortest mode string plus 3 in case of no missing? In this paper, theoretical analysis is made on the principle of algorithm construction firstly, and then the experimental results show that the algorithm can adapt to the binary bit stream data environment and extract the frequent sequence more accurately, the effect is obvious. Meanwhile, comparing with the classical AC algorithm and other improved algorithms, AC-<span class="hlt">IM</span> algorithm has a greater maximum jump distance and less time-consuming.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP31D1177G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP31D1177G"><span>Creating High-Resolution Maps of Leaf Water Isotopes Using <span class="hlt">IM</span>-CRDS and IRMS Techniques</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gerlein-Safdi, C.; Sinkler, C. J.; Caylor, K. K.</p> <p>2014-12-01</p> <p>Since the development of isotope ratio infrared spectroscopy (IRIS), the applications of water isotope analysis have been increasing. Here, we present a new protocol to create high-resolution maps of leaf water isotopes 18O and 2H. We use the Picarro induction module (<span class="hlt">IM</span>-CRDS) combined with an isotope analyzer (L2130-i) to sample up to 25 locations in one half of each leaf. Each sampling location corresponds to four samples (6 mm outside diameter punched-holes) punched next to each other. In the induction module, an induction coil heats a metal holder containing the leaf sample. The sample will release water vapor that is then sent to the isotope analyzer. The <span class="hlt">IM</span>-CRDS allows us to significantly reduce the sample size and therefore increase the sample density, compared to the traditional cryogenic extraction method. Using spatial analysis tools, we create high-resolution spatial maps of each isotope as well as d-excess maps. The water in the second half of the leaf is extracted by cryogenic extraction and analyzed using both IRIS and isotope ratio mass spectroscopy. The isotopic composition of the extracted water is compared to the average composition calculated from the maps and used for calibration. We present applications of this protocol to the analysis of the spatio-temporal evolution of foliar uptake in Colocasia esculenta under laboratory conditions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21164894','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21164894"><span><span class="hlt">Im</span>FCS: a software for imaging FCS data analysis and visualization.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sankaran, Jagadish; Shi, Xianke; Ho, Liang Yoong; Stelzer, Ernst H K; Wohland, Thorsten</p> <p>2010-12-06</p> <p>The multiplexing of fluorescence correlation spectroscopy (FCS), especially in imaging FCS using fast, sensitive array detectors, requires the handling of large amounts of data. One can easily collect in excess of 100,000 FCS curves a day, too many to be treated manually. Therefore, <span class="hlt">Im</span>FCS, an open-source software which relies on standard image files was developed and provides a wide range of options for the calculation of spatial and temporal auto- and cross-correlations, as well as differences in Cross-Correlation Functions (ΔCCF). <span class="hlt">Im</span>FCS permits fitting of standard models to correlation functions and provides optimized histograms of fitted parameters. Applications include the measurement of diffusion and flow with Imaging Total Internal Reflection FCS (ITIR-FCS) and Single Plane Illumination Microscopy FCS (SPIM-FCS) in biologically relevant samples. As a compromise between ITIR-FCS and SPIM-FCS, we extend the applications to Imaging Variable Angle-FCS (IVA-FCS) where sub-critical oblique illumination provides sample sectioning close to the cover slide.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008SPIE.6919E..0TA','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008SPIE.6919E..0TA"><span><span class="hlt">Im</span>TK: an open source multi-center information management toolkit</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Alaoui, Adil; Ingeholm, Mary Lou; Padh, Shilpa; Dorobantu, Mihai; Desai, Mihir; Cleary, Kevin; Mun, Seong K.</p> <p>2008-03-01</p> <p>The Information Management Toolkit (<span class="hlt">Im</span>TK) Consortium is an open source initiative to develop robust, freely available tools related to the information management needs of basic, clinical, and translational research. An open source framework and agile programming methodology can enable distributed software development while an open architecture will encourage interoperability across different environments. The ISIS Center has conceptualized a prototype data sharing network that simulates a multi-center environment based on a federated data access model. This model includes the development of software tools to enable efficient exchange, sharing, management, and analysis of multimedia medical information such as clinical information, images, and bioinformatics data from multiple data sources. The envisioned <span class="hlt">Im</span>TK data environment will include an open architecture and data model implementation that complies with existing standards such as Digital Imaging and Communications (DICOM), Health Level 7 (HL7), and the technical framework and workflow defined by the Integrating the Healthcare Enterprise (IHE) Information Technology Infrastructure initiative, mainly the Cross Enterprise Document Sharing (XDS) specifications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017heut.book..683D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017heut.book..683D"><span>Ganzheitliche Digitalisierungsansätze <span class="hlt">im</span> Stadtwerk: Von der Strategie bis zur Umsetzung</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Dudenhausen, Roman; Hahn, Heike</p> <p></p> <p>Digitalisierung muss <span class="hlt">im</span> Stadtwerk dazu führen, Kundenerwartungen, die heutzutage schon vielfach durch digitales Know-how und Erfahrungen geprägt sind, in einzigartiger Weise zu entsprechen - in Form digitaler Kundenkontaktpunkte, automatisierter Prozesse oder plattformbasierter Geschäftsmodelle. Eine große Rolle spielen dabei unternehmensweit nutzbare Informationen, die eine 360-Grad-Sicht auf den Kunden ermöglichen. Nur in dieser Kombination werden sich nachhaltig Wettbewerbsvorteile generieren lassen. Manch ein Kunde wird die Lust, einen Prozess zu Ende zu gehen, schon vor dem Abschluss verlieren, wenn er nicht unmittelbar und ohne die digitale Welt zu verlassen zum Ziel kommt. Eine nur "halb digitale Kundenerfahrung" wird weder zu Neugeschäft noch zur positiven emotionalen Bindung zwischen Kunden und Stadtwerk führen. Nicht zu unterschätzen sind zudem Erwartungen hinsichtlich zukünftiger Geschäftsmodelle, aus denen sich disruptive Bedrohungen für die herkömmlichen Strom- und Gasangebote ergeben werden. Erste innovative Ansätze finden sich bereits <span class="hlt">im</span> Markt, die erahnen lassen, dass zurzeit viel diskutierte Technologien wie die Blockchain nicht mehr nur hypothetischer Natur sind. Die Auseinandersetzung mit der Digitalisierung erfolgt dabei sinnvollerweise in einem unternehmensweit abgestimmten Rahmen, der eine zielgerichtete und ganzheitliche Vorgehensweise ermöglicht.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19990031806&hterms=Search+Extraterrestrial+Intelligence&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DSearch%2BExtraterrestrial%2BIntelligence','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19990031806&hterms=Search+Extraterrestrial+Intelligence&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DSearch%2BExtraterrestrial%2BIntelligence"><span>A Helium GC/<span class="hlt">IMS</span> for the Analysis of Extraterrestrial Volatiles in Exobiology Flight Experiments</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Carle, Glenn C.; Humphry, Donald E.; Shao, Maxine; Takeuchi, Nori</p> <p>1995-01-01</p> <p>For exobiology experiments on board spacecraft or space probes, a wide range of chemical species often must be detected and identified. The limited amount of power and space available for flight instruments severely limits the number of instruments that can be flown on any given mission. It is important then, that these experiments utilize instrumentation with universal response, so that all species of interest can be analyzed. Instrumentation to fulfill the analytical requirements of exobiology experiments has been developed utilizing Gas Chromatography - Ion Mobility Spectrometry. The Gas Chromatograph (GC) combines columns developed specifically for the complex mixtures anticipated with highly sensitive Metastable Ionization Detectors (a type of Helium Ionization Detector). To satisfy the limitations placed on resources, the Ion Mobility Spectrometer (<span class="hlt">IMS</span>) uses the same ultra high purity helium as the GC. This GC-MS provides the analytical capability to fulfill a wide range of exobiology flight experiment applications and has been included on a proposed Discovery Mission and proposals for both Lander and Orbiter of the European Space Agency's Rosetta Comet Mission. A data base of helium <span class="hlt">IMS</span> spectra is now being built for these future applications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011dui..book..321T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011dui..book..321T"><span>Ein Entscheidungsmodell zur Weitergabe persönlicher Daten <span class="hlt">im</span> Internet</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Treiblmaier, Horst</p> <p></p> <p>In den vergangenen zwei Jahrzehnten wandelte sich das Internet von einer Spielwiese für technikbegeisterte Computerspezialisten zu einem vielseitig einsetzbaren weltweiten Netzwerk für Privatpersonen und Unternehmen. Maßgeblichen Anteil daran besaß die rasante Entwicklung des World Wide Web (WWW), das, durch die Möglichkeit multimediale Inhalte zu vermitteln, für einen großen Teil der Bevölkerung industrialisierter Länder zu einem wesentlichen Bestandteil des täglichen Lebens wurde. Dass diese Entwicklung noch lange nicht abgeschlossen ist, zeigt die derzeitige Diskussion zum Thema Web 2.0 bzw. 3.0. Waren es in den letzten Jahren die hohen Umsatzzuwächse <span class="hlt">im</span> E-Commerce und multimedial gestaltete Webseiten in Kombination mit aufwändigen Applikationen, die für ständig steigende Nutzerzahlen <span class="hlt">im</span> World Wide Web sorgten, so wird dieser Innovationsschub nunmehr durch eine Vielzahl von Anwendungen fortgesetzt, die sich durch die zunehmende Vernetzung der Nutzer untereinander auszeichnen.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4266640','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4266640"><span><span class="hlt">IM</span>-TORNADO: A Tool for Comparison of 16S Reads from Paired-End Libraries</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jeraldo, Patricio; Kalari, Krishna; Chen, Xianfeng; Bhavsar, Jaysheel; Mangalam, Ashutosh; White, Bryan; Nelson, Heidi; Kocher, Jean-Pierre; Chia, Nicholas</p> <p>2014-01-01</p> <p>Motivation 16S rDNA hypervariable tag sequencing has become the de facto method for accessing microbial diversity. Illumina paired-end sequencing, which produces two separate reads for each DNA fragment, has become the platform of choice for this application. However, when the two reads do not overlap, existing computational pipelines analyze data from read separately and underutilize the information contained in the paired-end reads. Results We created a workflow known as Illinois Mayo Taxon Organization from RNA Dataset Operations (<span class="hlt">IM</span>-TORNADO) for processing non-overlapping reads while retaining maximal information content. Using synthetic mock datasets, we show that the use of both reads produced answers with greater correlation to those from full length 16S rDNA when looking at taxonomy, phylogeny, and beta-diversity. Availability and Implementation <span class="hlt">IM</span>-TORNADO is freely available at http://sourceforge.net/projects/imtornado and produces BIOM format output for cross compatibility with other pipelines such as QIIME, mothur, and phyloseq. PMID:25506826</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JGRA..121.8317R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JGRA..121.8317R"><span>Survey of pickup ion signatures in the vicinity of Titan using CAPS/<span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Regoli, L. H.; Coates, A. J.; Thomsen, M. F.; Jones, G. H.; Roussos, E.; Waite, J. H.; Krupp, N.; Cox, G.</p> <p>2016-09-01</p> <p>Pickup ion detection at Titan is challenging because ion cyclotron waves are rarely detected in the vicinity of the moon. In this work, signatures left by freshly produced pickup heavy ions (m/q ˜ 16 to m/q ˜ 28) as detected in the plasma data by the Cassini Plasma Spectrometer/Ion Mass Spectrometer (CAPS/<span class="hlt">IMS</span>) instrument on board Cassini are analyzed. In order to discern whether these correspond to ions of exospheric origin, one of the flybys during which the reported signatures were observed is investigated in detail. For this purpose, ion composition data from time-of-flight measurements and test particle simulations to constrain the ions' origin are used. After being validated, the detection method is applied to all the flybys for which the CAPS/<span class="hlt">IMS</span> instrument gathered valid data, constraining the region around the moon where the signatures are observed. The results reveal an escape region located in the anti-Saturn direction as expected from the nominal corotation electric field direction. These findings provide new constraints for the area of freshly produced pickup ion escape, giving an approximate escape rate of 3.3-2+3×1023 ions· s-1.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1995imsp.work...57K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1995imsp.work...57K"><span>The mini-CIDEX GC/<span class="hlt">IMS</span>: Analysis of cometary ice and dust</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kojiro, Daniel R.; Carle, Glenn C.; Humphry, Donald E.; Shao, Maxine; Takeuchi, Nori</p> <p>1995-04-01</p> <p>Comets are recognized as among the most scientifically important objects in the solar system. They are presumed relics of the early primitive material in the solar nebula and are believed to have provided a general enrichment of volatiles to the inner solar system. The Cometary Coma Chemical Composition (C4) Mission, a proposed Discovery-Class Mission, will analyze materials released into the coma, providing information leading to the understanding of the chemical composition and make-up of the cometary nucleus. As one of two scientific instruments in the C4 spacecraft, an advanced and streamlined version of the Cometary Ice and Dust Experiment (CIDEX), a mini-CIDEX, will employ an X-Ray Fluorescence (XRF) spectrometer to determine bulk elemental composition of cometary dust grains and a Gas Chromatograph/Ion Mobility Spectrometer (GC/<span class="hlt">IMS</span>) for determination of the molecular composition of dust and ices following stepwise pyrolysis and combustion. A description of the mini-CIDEX <span class="hlt">IMS</span> will be provided as well as data from analyses conducted using the mini-CIDEX breadboard instrument.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28950182','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28950182"><span><span class="hlt">IM</span>-UFF: Extending the universal force field for interactive molecular modeling.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jaillet, Léonard; Artemova, Svetlana; Redon, Stephane</p> <p>2017-09-05</p> <p>The universal force field (UFF) is a broadly applicable classical force field that contains parameters for almost every atom type of the periodic table. This force field is non-reactive, i.e. the topology of the system under study is considered as fixed and no creation or breaking of covalent bonds is possible. This paper introduces interactive modeling-UFF (<span class="hlt">IM</span>-UFF), an extension of UFF that combines the possibility to significantly modify molecular structures (as with reactive force fields) with a broad diversity of supported systems thanks to the universality of UFF. Such an extension lets the user easily build and edit molecular systems interactively while being guided by physics based inter-atomic forces. This approach introduces weighted atom types and weighted bonds, used to update topologies and atom parameterizations at every time step of a simulation. <span class="hlt">IM</span>-UFF has been evaluated on a large set of benchmarks and is proposed as a self-contained implementation integrated in a new module for the SAMSON software platform for computational nanoscience available at http://www.samson-connect.net. Copyright © 2017 Elsevier Inc. All rights reserved.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_16 --> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ExA....42..387H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ExA....42..387H"><span>AQUAdex<span class="hlt">IM</span>: highly efficient in-memory indexing and querying of astronomy time series images</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hong, Zhi; Yu, Ce; Wang, Jie; Xiao, Jian; Cui, Chenzhou; Sun, Jizhou</p> <p>2016-12-01</p> <p>Astronomy has always been, and will continue to be, a data-based science, and astronomers nowadays are faced with increasingly massive datasets, one key problem of which is to efficiently retrieve the desired cup of data from the ocean. AQUAdex<span class="hlt">IM</span>, an innovative spatial indexing and querying method, performs highly efficient on-the-fly queries under users' request to search for Time Series Images from existing observation data on the server side and only return the desired FITS images to users, so users no longer need to download entire datasets to their local machines, which will only become more and more impractical as the data size keeps increasing. Moreover, AQUAdex<span class="hlt">IM</span> manages to keep a very low storage space overhead and its specially designed in-memory index structure enables it to search for Time Series Images of a given area of the sky 10 times faster than using Redis, a state-of-the-art in-memory database.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23443804','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23443804"><span>Activity of a Py-<span class="hlt">Im</span> polyamide targeted to the estrogen response element.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nickols, Nicholas G; Szablowski, Jerzy O; Hargrove, Amanda E; Li, Benjamin C; Raskatov, Jevgenij A; Dervan, Peter B</p> <p>2013-05-01</p> <p>Pyrrole-imidazole (Py-<span class="hlt">Im</span>) polyamides are a class of programmable DNA minor groove binders capable of modulating the activity of DNA-binding proteins and affecting changes in gene expression. Estrogen receptor alpha (ERα) is a ligand-activated hormone receptor that binds as a homodimer to estrogen response elements (ERE) and is a driving oncogene in a majority of breast cancers. We tested a selection of structurally similar Py-<span class="hlt">Im</span> polyamides with differing DNA sequence specificity for activity against 17β-estadiol (E2)-induced transcription and cytotoxicity in ERα positive, E2-stimulated T47DKBluc cells, which express luciferase under ERα control. The most active polyamide targeted the sequence 5'-WGGWCW-3' (W = A or T), which is the canonical ERE half site. Whole transcriptome analysis using RNA-Seq revealed that treatment of E2-stimulated breast cancer cells with this polyamide reduced the effects of E2 on the majority of those most strongly affected by E2 but had much less effect on the majority of E2-induced transcripts. In vivo, this polyamide circulated at detectable levels following subcutaneous injection and reduced levels of ER-driven luciferase expression in xenografted tumors in mice after subcutaneous compound administration without significant host toxicity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19950026849','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19950026849"><span>The mini-CIDEX GC/<span class="hlt">IMS</span>: Analysis of cometary ice and dust</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Carle, Glenn C.; Humphry, Donald E.; Shao, Maxine; Takeuchi, Nori</p> <p>1995-01-01</p> <p>Comets are recognized as among the most scientifically important objects in the solar system. They are presumed relics of the early primitive material in the solar nebula and are believed to have provided a general enrichment of volatiles to the inner solar system. The Cometary Coma Chemical Composition (C4) Mission, a proposed Discovery-Class Mission, will analyze materials released into the coma, providing information leading to the understanding of the chemical composition and make-up of the cometary nucleus. As one of two scientific instruments in the C4 spacecraft, an advanced and streamlined version of the Cometary Ice and Dust Experiment (CIDEX), a mini-CIDEX, will employ an X-Ray Fluorescence (XRF) spectrometer to determine bulk elemental composition of cometary dust grains and a Gas Chromatograph/Ion Mobility Spectrometer (GC/<span class="hlt">IMS</span>) for determination of the molecular composition of dust and ices following stepwise pyrolysis and combustion. A description of the mini-CIDEX <span class="hlt">IMS</span> will be provided as well as data from analyses conducted using the mini-CIDEX breadboard instrument.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20150000592','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20150000592"><span>The Development of Cockpit Display and Alerting Concepts for Interval Management (<span class="hlt">IM</span>) in a Near-Term Environment</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Baxley, Brian T.; Shay, Richard F.; Swieringa, Kurt A.</p> <p>2014-01-01</p> <p>The National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC) Interval Management (<span class="hlt">IM</span>) research team has conducted a wide spectrum of work in the recent past, ranging from development and testing of the concept, procedures, and algorithm. This document focuses on the research and evaluation of the <span class="hlt">IM</span> pilot interfaces, cockpit displays, indications, and alerting concepts for conducting <span class="hlt">IM</span> spacing operations. The research team incorporated knowledge of human factors research, industry standards for cockpit design, and cockpit design philosophies to develop innovative displays for conducting these spacing operations. The research team also conducted a series of human-in-the-loop (HITL) experiments with commercial pilots and air traffic controllers, in as realistic a high-density arrival operation environment as could be simulated, to evaluate the spacing guidance display features and interface requirements needed to conduct spacing operations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22497124','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22497124"><span>[Rapid detection of residual cyclohexanone in disposable medical devices by ultraviolet photoionization ion mobility spectrometry (UV-<span class="hlt">IMS</span>)].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Hu; Han, Hai-yan; Niu, Wen-qi; Wang, Hong-mei; Huang, Chao-qun; Jiang, Hai-he; Chu, Yan-nan</p> <p>2012-01-01</p> <p>In the manufacture of disposable PVC medical devices, cyclohexanone is frequently used as an adhesive reagent, which can be released into the tube airspace or stored solution and thus may cause some adverse effects on patients in therapy. In this paper, an ultraviolet photoionization ion mobility spectrometry (UV-<span class="hlt">IMS</span>) technique has been developed to detect cyclohexanone through monitoring the gas composition within a package of infusion sets. The concentrations of cyclohexanone were prepared by means of exponential dilution method, and the experiments show that the UV-<span class="hlt">IMS</span> has a limit of detection at 15 ppb and its measurable linear dynamics range is over three orders of magnitude. The concentrations of cyclohexanone in three brands of infusion sets packages were determined to be 16.78, 17.59 and 46.69 ppm respectively. The UV-<span class="hlt">IMS</span> is proposed as a tool for the quality control of medical devices to monitor illegal uses of chemical solvents like cyclohexanone.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JASMS..28.1192C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JASMS..28.1192C"><span>Online Hydrogen-Deuterium Exchange Traveling Wave Ion Mobility Mass Spectrometry (HDX-<span class="hlt">IM</span>-MS): a Systematic Evaluation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cryar, Adam; Groves, Kate; Quaglia, Milena</p> <p>2017-06-01</p> <p>Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is an important tool for measuring and monitoring protein structure. A bottom-up approach to HDX-MS provides peptide level deuterium uptake values and a more refined localization of deuterium incorporation compared with global HDX-MS measurements. The degree of localization provided by HDX-MS is proportional to the number of peptides that can be identified and monitored across an exchange experiment. Ion mobility spectrometry (<span class="hlt">IMS</span>) has been shown to improve MS-based peptide analysis of biological samples through increased separation capacity. The integration of <span class="hlt">IMS</span> within HDX-MS workflows has been commercialized but presently its adoption has not been widespread. The potential benefits of <span class="hlt">IMS</span>, therefore, have not yet been fully explored. We herein describe a comprehensive evaluation of traveling wave ion mobility integrated within an online-HDX-MS system and present the first reported example of UDMSE acquisition for HDX analysis. Instrument settings required for optimal peptide identifications are described and the effects of detector saturation due to peak compression are discussed. A model system is utilized to confirm the comparability of HDX-<span class="hlt">IM</span>-MS and HDX-MS uptake values prior to an evaluation of the benefits of <span class="hlt">IMS</span> at increasing sample complexity. Interestingly, MS and <span class="hlt">IM</span>-MS acquisitions were found to identify distinct populations of peptides that were unique to the respective methods, a property that can be utilized to increase the spatial resolution of HDX-MS experiments by >60%. [Figure not available: see fulltext.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3296617','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3296617"><span>Evaluation of the Indian Migration Study Physical Activity Questionnaire (<span class="hlt">IMS</span>-PAQ): a cross-sectional study</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2012-01-01</p> <p>Background Socio-cultural differences for country-specific activities are rarely addressed in physical activity questionnaires. We examined the reliability and validity of the Indian Migration Study Physical Activity Questionnaire (<span class="hlt">IMS</span>-PAQ) in urban and rural groups in India. Methods A sub-sample of <span class="hlt">IMS</span> participants (n = 479) was used to examine short term (≤1 month [n = 158]) and long term (> 1 month [n = 321]) <span class="hlt">IMS</span>-PAQ reliability for levels of total, sedentary, light and moderate/vigorous activity (MVPA) intensity using intraclass correlation (ICC) and kappa coefficients (k). Criterion validity (n = 157) was examined by comparing the <span class="hlt">IMS</span>-PAQ to a uniaxial accelerometer (ACC) worn ≥4 days, via Spearman's rank correlations (ρ) and k, using Bland-Altman plots to check for systematic bias. Construct validity (n = 7,000) was established using linear regression, comparing <span class="hlt">IMS</span>-PAQ against theoretical constructs associated with physical activity (PA): BMI [kg/m2], percent body fat and pulse rate. Results <span class="hlt">IMS</span>-PAQ reliability ranged from ICC 0.42-0.88 and k = 0.37-0.61 (≤1 month) and ICC 0.26 to 0.62; kappa 0.17 to 0.45 (> 1 month). Criterion validity was ρ = 0.18-0.48; k = 0.08-0.34. Light activity was underestimated and MVPA consistently and substantially overestimated for the <span class="hlt">IMS</span>-PAQ vs. the accelerometer. Criterion validity was moderate for total activity and MVPA. Reliability and validity were comparable for urban and rural participants but lower in women than men. Increasing time spent in total activity or MVPA, and decreasing time in sedentary activity were associated with decreasing BMI, percent body fat and pulse rate, thereby demonstrating construct validity. Conclusion <span class="hlt">IMS</span>-PAQ reliability and validity is similar to comparable self-reported instruments. It is an appropriate tool for ranking PA of individuals in India. Some refinements may be required for sedentary populations and women in India. PMID:22321669</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.ars.usda.gov/research/publications/publication/?seqNo115=334316','TEKTRAN'); return false;" href="http://www.ars.usda.gov/research/publications/publication/?seqNo115=334316"><span>Characterization of developmental immature fiber (<span class="hlt">im</span>) mutant and Texas Marker-1 (TM-1) cotton fibers by Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) spectroscopy</span></a></p> <p><a target="_blank" href="https://www.ars.usda.gov/research/publications/find-a-publication/">USDA-ARS?s Scientific Manuscript database</a></p> <p></p> <p></p> <p>The immature fiber (<span class="hlt">im</span>) mutant is one type of cotton fiber mutants with unique characteristics of non-fluffy cotton bolls. Compared to its near-isogenic wild type Texas Marker-1 (TM-1), <span class="hlt">im</span> fiber has thin secondary cell wall and is less mature. In this work, we applied the previously proposed princip...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28106475','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28106475"><span>Characterization of Developmental Immature Fiber ( <span class="hlt">im</span>) Mutant and Texas Marker-1 (TM-1) Cotton Fibers Using Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Liu, Yongliang; Kim, Hee-Jin</p> <p>2017-01-01</p> <p>The immature fiber ( <span class="hlt">im</span>) mutant is one type of cotton fiber mutant with unique characteristics of non-fluffy cotton bolls. Compared to its near-isogenic wild type Texas Marker-1 (TM-1), <span class="hlt">im</span> fiber has a thin secondary cell wall and is less mature. In this work, we applied the previously proposed principal component analysis (PCA) and simple algorithms to analyze the attenuated total reflection Fourier transform infrared (ATR FT-IR) spectra of developmental <span class="hlt">im</span> and TM-1 fibers. The results from these approaches could not effectively and consistently indicate the inherent difference between TM-1 and <span class="hlt">im</span> fibers at the same developmental stage. The difference between TM-1 and corresponding <span class="hlt">im</span> fibers was detected when comparing the normalized intensity variations of the 730 cm(-1) bands. The 730 cm(-1) band intensities in developmental <span class="hlt">im</span> fibers are temporally lower than those in developmental TM-1 fibers although they became similar when the TM-1 and <span class="hlt">im</span> fibers are fully mature. The observation might imply the likelihood of temporal reduction of amorphous regions in developmental <span class="hlt">im</span> fibers rather than in developmental TM-1 fibers.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3951381','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3951381"><span>Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (<span class="hlt">IM</span>), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Enama, Mary E.; Ledgerwood, Julie E.; Novik, Laura; Nason, Martha C.; Gordon, Ingelise J.; Holman, LaSonji; Bailer, Robert T.; Roederer, Mario; Koup, Richard A.; Mascola, John R.; Nabel, Gary J.; Graham, Barney S.</p> <p>2014-01-01</p> <p>Background Phase 1 evaluation of the VRC HIV DNA and rAd5 vaccines delivered intramuscularly (<span class="hlt">IM</span>) supported proceeding to a Phase 2 b efficacy study. Here we report comparison of the <span class="hlt">IM</span>, subcutaneous (SC) and intradermal (ID) routes of administration. Methods Sixty subjects were randomized to 6 schedules to evaluate the <span class="hlt">IM</span>, SC or ID route for prime injections. Three schedules included DNA primes (Wks 0,4,8) and 3 schedules included rAd5 prime (Wk0); all included rAd5 <span class="hlt">IM</span> boost (Wk24). DNA vaccine dosage was 4 mg <span class="hlt">IM</span> or SC, but 0.4 mg ID, while all rAd5 vaccinations were 1010 PU. All injections were administered by needle and syringe. Results Overall, 27/30 subjects completed 3 DNA primes; 30/30 subjects completed rAd5 primes. Mild local pruritus (itchiness), superficial skin lesions and injection site nodules were associated with ID and SC, but not <span class="hlt">IM</span> injections. All routes induced T-cell and antibody immune responses after rAd5 boosting. Overall, >95% had Env antibody and >80% had Env T-cell responses. Conclusions The pattern of local reactogenicity following ID and SC injections differed from <span class="hlt">IM</span> injections but all routes were well-tolerated. There was no evidence of an immunogenicity advantage following SC or ID delivery, supporting <span class="hlt">IM</span> delivery as the preferred route of administration. Trial Registration Clinicaltrials.gov NCT00321061 PMID:24621858</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title5-vol2/pdf/CFR-2010-title5-vol2-sec894-507.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title5-vol2/pdf/CFR-2010-title5-vol2-sec894-507.pdf"><span>5 CFR 894.507 - After <span class="hlt">I'm</span> enrolled, may I change from one dental or vision plan or plan option to another?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-01-01</p> <p>... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false After <span class="hlt">I'm</span> enrolled, may I change from one... OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Enrollment and Changing Enrollment § 894.507 After <span class="hlt">I'm</span> enrolled, may I...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2014-title5-vol2/pdf/CFR-2014-title5-vol2-sec894-507.pdf','CFR2014'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2014-title5-vol2/pdf/CFR-2014-title5-vol2-sec894-507.pdf"><span>5 CFR 894.507 - After <span class="hlt">I'm</span> enrolled, may I change from one dental or vision plan or plan option to another?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2014&page.go=Go">Code of Federal Regulations, 2014 CFR</a></p> <p></p> <p>2014-01-01</p> <p>... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false After <span class="hlt">I'm</span> enrolled, may I change from one... OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Enrollment and Changing Enrollment § 894.507 After <span class="hlt">I'm</span> enrolled, may I...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title5-vol2/pdf/CFR-2011-title5-vol2-sec894-507.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title5-vol2/pdf/CFR-2011-title5-vol2-sec894-507.pdf"><span>5 CFR 894.507 - After <span class="hlt">I'm</span> enrolled, may I change from one dental or vision plan or plan option to another?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-01-01</p> <p>... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false After <span class="hlt">I'm</span> enrolled, may I change from one... OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Enrollment and Changing Enrollment § 894.507 After <span class="hlt">I'm</span> enrolled, may I...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22890806','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22890806"><span>Molecular markers associated with the immature fiber (<span class="hlt">im</span>) gene affecting the degree of fiber cell wall thickening in cotton (Gossypium hirsutum L.).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kim, Hee Jin; Moon, Hong S; Delhom, Christopher D; Zeng, Linghe; Fang, David D</p> <p>2013-01-01</p> <p>Cotton fiber fineness and maturity measured indirectly as micronaire (MIC) are important properties of determining fiber grades in the textile market. To understand the genetic control and molecular mechanisms of fiber fineness and maturity, we studied two near isogenic lines, Gossypium hirsutum, Texas Marker-1 wild type (TM-1) and immature fiber (<span class="hlt">im</span>) mutant showing a significant difference in MIC values. The fibers from <span class="hlt">im</span> mutant plants were finer and less mature with lower MIC values than those from the recurrent parent, TM-1. A comprehensive fiber property analysis of TM-1 and <span class="hlt">im</span> mutant showed that the lower MIC of fibers in <span class="hlt">im</span> mutant was due to the lower degree of fiber cell wall thickening as compared to the TM-1 fibers. Using an F(2) population comprising 366 progenies derived from a cross between TM-1 and <span class="hlt">im</span> mutant, we confirmed that the immature fiber phenotype present in a mutant plant was controlled by one single recessive gene <span class="hlt">im</span>. Furthermore, we identified 13 simple sequence repeat markers that were closely linked to the <span class="hlt">im</span> gene located on chromosome 3. Molecular markers associated with the <span class="hlt">im</span> gene will lay the foundation to further investigate genetic information required for improving cotton fiber fineness and maturity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title49-vol2/pdf/CFR-2010-title49-vol2-sec174-63.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title49-vol2/pdf/CFR-2010-title49-vol2-sec174-63.pdf"><span>49 CFR 174.63 - Portable tanks, <span class="hlt">IM</span> portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-10-01</p> <p>... 49 Transportation 2 2010-10-01 2010-10-01 false Portable tanks, <span class="hlt">IM</span> portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, <span class="hlt">IM</span> portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1019911','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1019911"><span>Luminescent Copper(I) Halide Butterfly Dimers Coordinated to [Au(CH3<span class="hlt">im</span>CH2py)2]BF4 and [Au(CH3<span class="hlt">im</span>CH2quin)2]BF4</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Catalano, V.; Moore, A; Shearer, J; Kim, J</p> <p>2009-01-01</p> <p>The coordination chemistry of copper(I) halides to the homoleptic, N-heterocyclic carbene Au(I) complexes [Au(CH{sub 3}<span class="hlt">im</span>CH{sub 2}quin){sub 2}]BF{sub 4} and [Au(CH{sub 3}<span class="hlt">im</span>CH{sub 2}py){sub 2}]BF{sub 4} was explored. The reaction of CuX (X = Cl, Br, I) with either [Au(CH{sub 3}<span class="hlt">im</span>CH{sub 2}quin){sub 2}]BF{sub 4} or [Au(CH{sub 3}<span class="hlt">im</span>CH{sub 2}py){sub 2}]BF{sub 4} produces trimetallic complexes containing Cu{sub 2}X{sub 2}-butterfly copper clusters coordinated to the two imine moieties. The triangular arrangement of the metals places the gold(I) center in close proximity ({approx}2.5-2.6 {angstrom}) to the centroid of the Cu-Cu vector. The Cu-Cu separations vary as a function of bridging halide with the shortest Cu-Cu separations of {approx}2.5 {angstrom} found in the iodo-complexes and the longest separations of 2.9 {angstrom} found in the bridging chloride complexes. In all six complexes the Au-Cu separations range from {approx}2.8 to 3.0 {angstrom}. In the absence of halides, the dimetallic complex [AuCu(CH{sub 3}<span class="hlt">im</span>CH{sub 2}py){sub 2}(NCCH{sub 3}){sub 2}](BF{sub 4}){sub 2}, containing a long Au-Cu distance of {approx}4.72 {angstrom} is formed. Additionally, as the byproduct of the reaction of CuBr with [Au(CH{sub 3}<span class="hlt">im</span>CH{sub 2}quin){sub 2}]BF{sub 4} the deep-red, dimetallic compound, AuCuBr{sub 2}(CH{sub 3}<span class="hlt">im</span>CH{sub 2}quin){sub 2}, was isolated in very low yield. All of these complexes were studied by NMR spectroscopy, mass spectrometry, and the copper containing species were additionally characterized by X-ray crystallography. In solution the copper centers dissociate from the gold complexes, but as shown by XANES and EXAFS spectroscopy, at low temperature the Cu-Cu linkage is broken, and the individual copper(I) halides reposition themselves to opposite sides of the gold complex while remaining coordinated to one imine moiety. In the solid state all of the complexes are photoluminescent, though the nature of the excited state was not determined.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NuPhB.916..414I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NuPhB.916..414I"><span>ODE/<span class="hlt">IM</span> correspondence for modified B2(1) affine Toda field equation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ito, Katsushi; Shu, Hongfei</p> <p>2017-03-01</p> <p>We study the massive ODE/<span class="hlt">IM</span> correspondence for modified B2(1) affine Toda field equation. Based on the ψ-system for the solutions of the associated linear problem, we obtain the Bethe ansatz equations. We also discuss the T-Q relations, the T-system and the Y-system, which are shown to be related to those of the A3 /Z2 integrable system. We consider the case that the solution of the linear problem has a monodromy around the origin, which imposes nontrivial boundary conditions for the T-/Y-system. The high-temperature limit of the T- and Y-system and their monodromy dependence are studied numerically.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19900064163&hterms=balsiger&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Dbalsiger','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19900064163&hterms=balsiger&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Dbalsiger"><span>Cometary ion flow variations at Comet P/Halley as observed by the Giotto <span class="hlt">IMS</span> experiment</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kettmann, G.; Ip, W.-H.; Balsiger, H.; Meier, A.; Goldstein, B. E.</p> <p>1990-01-01</p> <p>The moments of the cometary-ion distributions are determined through a three-dimensional analysis of the Giotto <span class="hlt">IMS</span> high-intensity spectrometer (HIS) data. The spectrometer is described, with emphasis on its angle analyzer and mass analyzer. The method of data analysis is outlined, with ion-flow vectors and temperatures being addressed. The results of the water group ion-flow profile are presented, and it is noted that, after crossing the cometopause region, the ions become gradually colder. At cometocentric distances larger than 130,000 km, the cometary-ion temperature is found to be in the area of 100 eV or higher, and derivations of the flow parameters are uncertain. The ion temperature and the flow speed become lower by about 50 eV after crossing the magnetic pile-up boundary. It is concluded that the observed velocity and temperature profiles can be explained on the basis of charge exchange processes.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008IJMPB..22.1461K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008IJMPB..22.1461K"><span>a Study of 954-2A/<span class="hlt">IM</span>7 Composite Laminates Containing a Central Hole</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kim, Hyungwon</p> <p></p> <p>Predicting microcracking properties of the composite laminates in nonuniform stress conditions was the subject in this paper. The uniform stress field meant the stresses were independent of the width direction. The material was the 954-2A/<span class="hlt">IM</span>7 laminates containing a central hole. Microcracks initiated at the edge of the hole and propagated into the laminate. Because the tensile stress concentration decreased with distance, the microcracks were arrested before the edge of the laminate. Because carbon fiber composites were opaque, a x-ray method was used to detect the length of the propagating microcracks. The microcracking at the near edge of the hole could be reasonably predicted by considering the local laminate stresses and the microcracking toughness measured in unnotched laminates. However, the data away from the hole did not agree with the predictions. The local microcrack density was always much higher than that predicted by the local laminate stress.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015SPIE.9658E..05C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015SPIE.9658E..05C"><span>Investigation of local registration performance of <span class="hlt">IMS</span> Nanofabrication's Multi-Beam Mask Writer</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chalom, Daniel; Klikovits, Jan; Geist, David; Hudek, Peter; Eder-Kapl, Stefan; Daneshpanah, Mehdi; Laske, Frank; Eyring, Stefan; Roeth, Klaus-Dieter</p> <p>2015-07-01</p> <p>Reticles for manufacturing upcoming 10nm and 7nm Logic devices will become very complex, no matter whether 193nm water immersion lithography will continue as main stream production path or EUV lithography will be able to take over volume production of critical layers for the 7nm node. The economic manufacturing of future masks for 193i, EUV and imprint lithography with further increasing complexity drives the need for multi-beam mask writing as this technology can overcome the influence of complexity on write time of today's common variable shape beam writers. Local registration of the multi-beam array is a critical component which greatly differs from variable shape beam systems. In this paper we would like to present the local registration performance of the <span class="hlt">IMS</span> Multi-Beam Mask Writer system and the metrology tools that enable the characterization optimization.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_17 --> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22317138','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22317138"><span>Prevention of MSD within OHSMS/<span class="hlt">IMS</span>: a systematic review of risk assessment strategies.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yazdani, Amin; Wells, Richard</p> <p>2012-01-01</p> <p>The purpose of this systematic review was to identify and summarize the research evidence on prevention of Musculoskeletal Disorders (MSD) within Occupational Health and Safety Management Systems (OHSMS) and Integrated Management Systems (<span class="hlt">IMS</span>). Databases in business, management, engineering and health and safety were systematically searched and relevant publications were synthesized. The number of papers that could address the research questions was small. However, the review revealed that many of the techniques to address MSD hazards require substantial background knowledge and training. This may limit employees' involvement in the technical aspects of the risk assessment process. Also these techniques did not usually fit into techniques used by companies to address other risk factors within their management systems. This could result in MSD prevention becoming a separate issue that cannot be managed with company-wide tools. In addition, this review also suggested that there is a research gap concerning the MSD prevention within companies' management systems.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100015640','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100015640"><span>Hypervelocity Impact Testing of <span class="hlt">IM</span>7/977-3 with Micro-Sized Particles</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Smith, J. G.; Jegley, D. C.; Siochi, E. J.; Wells, B. K.</p> <p>2010-01-01</p> <p>Ground-based hypervelocity imapct testing was conducted on <span class="hlt">IM</span>7/977-3 quasi-isotropic flat panels at normal incidence using micron-sized particles (i.e. less than or equal to 100 microns) of soda lime glass and olivine. Testing was performed at room temperature (RT) and 175 C with results from the 175 C test compared to those obtained at RT. Between 10 and 30 particles with velocities ranging from 5 to 13 km/s impacted each panel surface for each test temperature. Panels were ultrasonically scanned prior to and after impact testing to assess internal damage. Post-impact analysis included microscopic examination of the surface, determination of particle speed and location, and photomicroscopy for microcrack assessment. Internal damage was observed by ultrasonic inspection on panels impacted at 175 C, whereas damage for the RT impacted panels was confined to surface divets/craters as determined by microscopic analysis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://pubs.er.usgs.gov/publication/70030478','USGSPUBS'); return false;" href="http://pubs.er.usgs.gov/publication/70030478"><span>Useful ion yields for Cameca <span class="hlt">IMS</span> 3f and 6f SIMS: Limits on quantitative analysis</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Hervig, R.L.; Mazdab, F.K.; Williams, Pat; Guan, Y.; Huss, G.R.; Leshin, L.A.</p> <p>2006-01-01</p> <p>The useful yields (ions detected/atom sputtered) of major and trace elements in NIST 610 glass were measured by secondary ion mass spectrometry (SIMS) using Cameca <span class="hlt">IMS</span> 3f and 6f instruments. Useful yields of positive ions at maximum transmission range from 10-4 to 0.2 and are negatively correlated with ionization potential. We quantified the decrease in useful yields when applying energy filtering or high mass resolution techniques to remove molecular interferences. The useful yields of selected negative ions (O, S, Au) in magnetite and pyrite were also determined. These data allow the analyst to determine if a particular analysis (trace element contents or isotopic ratio) can be achieved, given the amount of sample available and the conditions of the analysis. ?? 2005 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20833225','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20833225"><span>Alpha-conotoxin <span class="hlt">Im</span>I disrupts central control of swimming in the medicinal leech.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wagenaar, Daniel A; Gonzalez, Ruben; Ries, David C; Kristan, William B; French, Kathleen A</p> <p>2010-11-26</p> <p>Medicinal leeches (Hirudo spp.) swim using a metachronal, front-to-back undulation. The behavior is generated by central pattern generators (CPGs) distributed along the animal's midbody ganglia and is coordinated by both central and peripheral mechanisms. Here we report that a component of the venom of Conus imperialis, α-conotoxin <span class="hlt">Im</span>I, known to block nicotinic acetyl-choline receptors in other species, disrupts swimming. Leeches injected with the toxin swam in circles with exaggerated dorsoventral bends and reduced forward velocity. Fictive swimming in isolated nerve cords was even more strongly disrupted, indicating that the toxin targets the CPGs and central coordination, while peripheral coordination partially rescues the behavior in intact animals. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060015661&hterms=Business+mission&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3DBusiness%2Bmission','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060015661&hterms=Business+mission&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3DBusiness%2Bmission"><span>Miniature GC: Minicell ion mobility spectrometer (<span class="hlt">IMS</span>) for astrobiology planetary missions</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Holland, Paul M.; Stimac, Robert M.; Kaye, William J.; Takeuchi, Norishige</p> <p>2006-01-01</p> <p>Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or longer mission life for stationary landers/laboratories. We describe here the development of a miniature GC - Minicell Ion Mobility Spectrometer (<span class="hlt">IMS</span>) under development through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA's Small Business Innovative Research (SBIR) Program.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19880034206&hterms=transition+period&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dtransition%2Bperiod','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19880034206&hterms=transition+period&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dtransition%2Bperiod"><span>A flare event of the long-period RS Canum Venaticorum system <span class="hlt">IM</span> Pegasi</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Buzasi, Derek L.; Ramsey, Lawrence W.; Huenemoerder, David P.</p> <p>1987-01-01</p> <p>The characteristics of a flare event detected on the long-period RS CVn system <span class="hlt">IM</span> Pegasi are reported. The low-resolution spectrum show enhancements of up to a factor of five in some emission lines. All of the ultraviolet emission lines normally visible are enhanced significantly more than the normal 30 rotational modulation. Emission fluxes of both the quiescent and flare event are used to construct models of the density and temperature variation with height. These models reveal a downward shift of the transition region during the flare. Scaled models of the quiet and flaring solar outer atmosphere are used to estimate the filling factor of the flare event at about 30 percent of the stellar surface. The pattern of line enhancements in the flare is the same as a previous event in Lambda Andromeda observed previously.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22815358','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22815358"><span><span class="hlt">im</span>DEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Grapov, Dmitry; Newman, John W</p> <p>2012-09-01</p> <p>Interactive modules for Data Exploration and Visualization (<span class="hlt">im</span>DEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data through a user-friendly interface. Individual modules enables interactive and dynamic analyses of large data by interfacing R's multivariate statistics and highly customizable visualizations with the spreadsheet environment, aiding robust inferences and generating information-rich data visualizations. This tool provides access to multiple comparisons with false discovery correction, hierarchical clustering, principal and independent component analyses, partial least squares regression and discriminant analysis, through an intuitive interface for creating high-quality two- and a three-dimensional visualizations including scatter plot matrices, distribution plots, dendrograms, heat maps, biplots, trellis biplots and correlation networks. Freely available for download at http://sourceforge.net/projects/imdev/. Implemented in R and VBA and supported by Microsoft Excel (2003, 2007 and 2010).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20060015661&hterms=astrobiology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dastrobiology','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20060015661&hterms=astrobiology&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dastrobiology"><span>Miniature GC: Minicell ion mobility spectrometer (<span class="hlt">IMS</span>) for astrobiology planetary missions</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Holland, Paul M.; Stimac, Robert M.; Kaye, William J.; Takeuchi, Norishige</p> <p>2006-01-01</p> <p>Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or longer mission life for stationary landers/laboratories. We describe here the development of a miniature GC - Minicell Ion Mobility Spectrometer (<span class="hlt">IMS</span>) under development through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA's Small Business Innovative Research (SBIR) Program.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3515714','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3515714"><span>Mannose7 Glycan Isomer Characterization by <span class="hlt">IMS</span>-MS/MS Analysis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Zhu, Feifei; Lee, Sunyoung; Valentine, Stephen J.; Reilly, James P.; Clemmer, David E.</p> <p>2012-01-01</p> <p>The isomers of the Man7GlcNAc2 glycan obtained from bovine ribonuclease B have been characterized by ion mobility spectrometry-tandem mass spectrometry (<span class="hlt">IMS</span>-MS/MS). In these experiments, [Man7+2Na]2+ precursors having different mobilities are selected by ion mobility spectrometry and analyzed by MS/MS techniques in an ion trap. The fragmentation spectra obtained for various precursor ions are specific, suggesting the isolation or enrichment of different glycan isomers. One fragment ion with a mass-to-charge ratio (m/z) of 903.8 is found to correspond to the loss of an internal mannose residue of a specific isomer. Extracted fragment ion drift time distributions (XFIDTDs) yield distinctive precursor ion drift time profiles indicating the existence of four separate isomers as proposed previously. PMID:23055077</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA131845','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA131845"><span>GSE for Balloon-Borne <span class="hlt">I.M.S</span>.: Decommutator and D/A Units,</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1982-10-01</p> <p>UNLSSFEhEEEEE8-09 F968-hh I FG /6 EhhhLINhmm 11111 I1111115~ 111WERE~ AFGL-TR-83-0095 GSE FOR BALLOON-BORNE <span class="hlt">I.M.S</span>.: S DECOMMUTATOR AND D/A UNITS Raimundas Sukys ...R. Sukys J.S. Rochefort F19628-81-C-0162 9. PCRFO mr,,C OmG&Nkz&TIO NAb4E AND ADDR.S 0. P33IA. (L.1 E NT. V’,-o3= l. TASK No rtheaste rn Unive rs... Sukys , Steven Goldberq, Contrl,- Cir-cjits for Pocket Pa.l ac Neutra ization EprriiTlent and C’ther -, .ics , Scientific Report 1o. trw n Frtract E1 62</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.6851Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.6851Y"><span>Sound pressure level variations across the Pacific based on <span class="hlt">IMS</span> data</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yamada, Tomoaki; Haralabus, Georgios; Zampolli, Mario; Heaney, Kevin</p> <p>2017-04-01</p> <p>Low frequency hydro-acoustic waves can be detected at great distances due to low attenuation of acoustic energy in the SOund Fixing And Ranging (SOFAR) channel. These waves contain both acoustic source and propagation medium information which is difficult to separate at the receiving end. This study examines sound pressure level variations across the pacific using 100 underwater controlled sources near a landward slope zone in Japan to minimize source uncertainty. The data were acquired at water-column hydrophones of the hydroacoustic station HA03 at Chile that is part of the International Monitoring System (<span class="hlt">IMS</span>) of the Comprehensive Nuclear Test Ban Treaty. Acoustics waves were detected over 15,000 km across the Pacific and initial analysis indicates a maximum difference of the pressure level is 17 dB re. micro Pa.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA612378','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA612378"><span><span class="hlt">IHR</span> (2005) Compliance: Laboratory Capacities and Biological Risks</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2014-08-01</p> <p>compile guidance for infection prevention and control measures.11 This guidance includes transmission -based precautions for diseases such as...for Disease Control and Prevention (CDC); protocols published by laboratory credentialing organizations; and protocols published by professional...International Development and the US Centers for Disease Control and Prevention ) who participated in the Maputo consensus process also developed detailed</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA079524','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA079524"><span>Diorganostyrylzinndiorganophosphine und <span class="hlt">Ihre</span> Tricarbonylnickelkomplexe (Diorganostyryltin Phosphines and its Tricarbonylnickel Complexes).</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1979-12-03</p> <p>Umkristallisieren aus Pentan/Benzol/Toluol gereinigt werden konnen; IVb zeigt bereits ab 0°C Polym erisationserschei- nungen. Vb und VIb werden als heligelbe...einem Rar.ger Engeneering M6ssbauer Spectrometer benutzt wurde. in C 6 D 6c) die Ha lbwertsbreiten wurden als glei~h vorausgesetzt , um dos Si gnal als</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED286357.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED286357.pdf"><span><span class="hlt">Ihr</span> Ticket fur Munchen (Your Ticket to Munich).</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Singer, Debbie</p> <p></p> <p>Texts accompanied by photographs and drawings introduce students to four means of public transportation and to major tourist attractions in Munich, German Federal Republic. Vocabulary is glossed in the margin, and texts are followed by questions and exercises. Some suggestions for additional activities are given in English. An appendix includes…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011AGUFM.A31A0049L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011AGUFM.A31A0049L"><span>Incorporating numerical modelling into estimates of the detection capability of the <span class="hlt">IMS</span> infrasound network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Le Pichon, A.; Ceranna, L.</p> <p>2011-12-01</p> <p>To monitor compliance with the Comprehensive Nuclear-Test-Ban Treaty (CTBT), a dedicated International Monitoring System (<span class="hlt">IMS</span>) is being deployed. Recent global scale observations recorded by this network confirm that its detection capability is highly variable in space and time. Previous studies estimated the radiated source energy from remote observations using empirical yield-scaling relations which account for the along-path stratospheric winds. Although the empirical wind correction reduces the variance in the explosive energy versus pressure relationship, strong variability remains in the yield estimate. Today, numerical modelling techniques provide a basis to better understand the role of different factors describing the source and the atmosphere that influence propagation predictions. In this study, the effects of the source frequency and the stratospheric wind speed are simulated. In order to characterize fine-scale atmospheric structures which are excluded from the current atmospheric specifications, model predictions are further enhanced by the addition of perturbation terms. Thus, a theoretical attenuation relation is developed from massive numerical simulations using the Parabolic Equation method. Compared with previous studies, our approach provides a more realistic physical description of infrasound propagation. We obtain a new relation combining a near-field and far-field term which account for the effects of both geometrical spreading and dissipation on the pressure wave attenuation. By incorporating real ambient infrasound noise at the receivers which significantly limits the ability to detect and identify signals of interest, the minimum detectable source amplitude can be derived in a broad frequency range. Empirical relations between the source spectrum and the yield of explosions are used to infer detection thresholds in tons of TNT equivalent. In the context of the future verification of the CTBT, the obtained attenuation relation quantifies</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFM.S23B2504C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFM.S23B2504C"><span>On the fingerprint of ssw events in infrasound recordings at <span class="hlt">IMS</span> stations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ceranna, L.; Le Pichon, A.; Pilger, C.; Ross, O.</p> <p>2013-12-01</p> <p>It has been recently shown that sudden stratospheric warming (ssw) events have an impact on the detection of coherent infrasonic waves at dedicated arrays (e.g., Evers & Siegmund, 2009). During ssw events the polar vortex of prevailing stratospheric westerly winds in a winter hemisphere abruptly slows down or even reverses its direction along with an increase of stratospheric temperatures up to several tens of °C. Since infrasound arrays are mostly recording signals ducted in stratospheric wave-guides, such antennas are sensitive to changes in effective sound speed profiles - temperature plus wind speed in direction of propagation. Considering continuous infrasonic waves emitted by ocean swell (microbaroms), volcanoes or even anthropogenic sources as flares, a gap or a change in the back-azimuth of these detected signals can be observed at arrays. For the compliances with the verification of the Comprehensive Nuclear-Test-Ban Treaty a global network of 60 infrasound stations is under construction as a part of the International Monitoring System (<span class="hlt">IMS</span>); whereas 45 have already been installed. Analysis of waveform data recorded at these stations has demonstrated the capability of infrasound as a supplementary tool for remote sensing of the atmosphere. In our study we compare the re-analysis, using PMCC, of more than five years of continuous data at all available sites (see Matoza et al., 2013) with atmospheric descriptions provided by the EMCWF. We present a synoptic view of the fingerprint of ssw events in detection of coherent signals at <span class="hlt">IMS</span> infrasound stations both on northern and southern hemisphere, covering the full latitude range from Antarctica to Greenland.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013EGUGA..15.9628C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013EGUGA..15.9628C"><span>On the fingerprint of ssw events in infrasound recordings at <span class="hlt">IMS</span> stations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ceranna, Lars; Pilger, Christoph; Ross, Ole; Le Pichon, Alexis</p> <p>2013-04-01</p> <p>It has been recently shown that sudden stratospheric warming (ssw) events have an impact on the detection of coherent infrasonic waves at dedicated arrays (e.g., Evers & Siegmund, 2009). During ssw events the polar vortex of prevailing stratospheric westerly winds in a winter hemisphere abruptly slows down or even reverses its direction along with an increase of stratospheric temperatures up to several tens of °C. Since infrasound arrays are mostly recording signals ducted in stratospheric wave-guides, such antennas are sensitive to changes in effective sound speed profiles - temperature plus wind speed in direction of propagation. Considering continuous infrasonic waves emitted by ocean swell (microbaroms), volcanoes or even anthropogenic sources as flares, a gap or a change in the back-azimuth of these detected signals can be observed at arrays. For the compliances with the verification of the Comprehensive Nuclear-Test-Ban Treaty a global network of 60 infrasound stations is under construction as a part of the International Monitoring System (<span class="hlt">IMS</span>); whereas 45 have already been installed. Analysis of waveform data recorded at these stations has demonstrated the capability of infrasound as a supplementary tool for remote sensing of the atmosphere. In our study we compare the re-analysis, using PMCC, of more than five years of continuous data at all available sites (see Matoza et al., 2013) with atmospheric descriptions provided by the EMCWF. We present a synoptic view of the fingerprint of ssw events in detection of coherent signals at <span class="hlt">IMS</span> infrasound stations both on northern and southern hemisphere, covering the full latitude range from Antarctica to Greenland.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFM.A13C0199C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFM.A13C0199C"><span>Advancing <span class="hlt">IM</span>-CW Lidar Modulation Techniques for ASCENDS CO2 Column Measurements from Space</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Campbell, J. F.; Lin, B.; Nehrir, A. R.; Harrison, F. W.; Chen, S.; Obland, M. D.</p> <p>2013-12-01</p> <p>Global atmospheric carbon dioxide (CO2) measurements through the Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) decadal survey recommended space mission are critical for improving our understanding of CO2 sources and sinks. <span class="hlt">IM</span>-CW (Intensity Modulated Continuous Wave) lidar techniques are investigated as a means of facilitating CO2 measurements from space to meet the ASCENDS science requirements. In previous laboratory and flight experiments we have successfully used linear swept frequency modulation to discriminate surface lidar returns from intermediate aerosol and cloud contamination. Furthermore, high accuracy and precision ranging to the surface as well as to the top of intermediate clouds, which is a requirement for the inversion of the CO2 column mixing ratio from the instrument optical depth measurements, has been demonstrated with the linear swept frequency modulation technique. We are concurrently investigating advanced techniques to help improve the auto-correlation properties of the transmitted waveform implemented through physical hardware to make cloud rejection more robust in special restricted scenarios. Several different modulation techniques are compared including orthogonal linear swept, orthogonal non-linear swept, time shifted PN, sine wave modulated PN, and sine wave pulsed PN. Different PN code techniques are presented that are appropriate for different types of lidar hardware, including our current ASCENDS <span class="hlt">IM</span>-CW concept space hardware. These techniques have excellent auto-correlation properties without sidelobes while possessing a finite bandwidth (by way of a new cyclic digital filter), which will reduce bias error in the presence of multiple scatterers. Our analyses show that the studied modulation techniques can increase the accuracy of CO2 column measurements from space.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20160006610','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20160006610"><span>Regional and Global Atmospheric CO2 Measurements Using 1.57 Micron <span class="hlt">IM</span>-CW Lidar</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Lin, Bing; Obland, Michael; Nehrir, Amin; Browell, Edward; Harrison, F. Wallace; Dobler, Jeremy; Campbell, Joel; Kooi, Susan; Meadows, Byron; Fan, Tai-Fang; <a style="text-decoration: none; " href="javascript:void(0); " onClick="displayelement('author_20160006610'); toggleEditAbsImage('author_20160006610_show'); toggleEditAbsImage('author_20160006610_hide'); "> <img style="display:inline; width:12px; height:12px; " src="images/arrow-up.gif" width="12" height="12" border="0" alt="hide" id="author_20160006610_show"> <img style="width:12px; height:12px; display:none; " src="images/arrow-down.gif" width="12" height="12" border="0" alt="hide" id="author_20160006610_hide"></p> <p>2015-01-01</p> <p>Atmospheric CO2 is a critical forcing for the Earth's climate, and knowledge of its distribution and variations influences predictions of the Earth's future climate. Accurate observations of atmospheric CO2 are also crucial to improving our understanding of CO2 sources, sinks and transports. To meet these science needs, NASA is developing technologies for the Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) space mission, which is aimed at global CO2 observations. Meanwhile an airborne investigation of atmospheric CO2 distributions as part of the NASA Suborbital Atmospheric Carbon and Transport â€" America (ACT-America) mission will be conducted with lidar and in situ instrumentation over the central and eastern United States during all four seasons and under a wide range of meteorological conditions. In preparing for the ASCENDS mission, NASA Langley Research Center and Exelis Inc./Harris Corp. have jointly developed and demonstrated the capability of atmospheric CO2 column measurements with an intensity-modulated continuous-wave (<span class="hlt">IM</span>-CW) lidar. Since 2005, a total of 14 flight campaigns have been conducted. A measurement precision of approx.0.3 ppmv for a 10-s average over desert and vegetated surfaces has been achieved, and the lidar CO2 measurements also agree well with in-situ observations. Significant atmospheric CO2 variations on various spatiotemporal scales have been observed during these campaigns. For example, around 10-ppm CO2 changes were found within free troposphere in a region of about 200A-300 sq km over Iowa during a summer 2014 flight. Results from recent flight campaigns are presented in this paper. The ability to achieve the science objectives of the ASCENDS mission with an <span class="hlt">IM</span>-CW lidar is also discussed in this paper, along with the plans for the ACT-America aircraft investigation that begins in the winter of 2016.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012JGRD..117.5121L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012JGRD..117.5121L"><span>Incorporating numerical modeling into estimates of the detection capability of the <span class="hlt">IMS</span> infrasound network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Le Pichon, A.; Ceranna, L.; Vergoz, J.</p> <p>2012-03-01</p> <p>To monitor compliance with the Comprehensive Nuclear-Test ban Treaty (CTBT), a dedicated International Monitoring System (<span class="hlt">IMS</span>) is being deployed. Recent global scale observations recorded by this network confirm that its detection capability is highly variable in space and time. Previous studies estimated the radiated source energy from remote observations using empirical yield-scaling relations which account for the along-path stratospheric winds. Although the empirical wind correction reduces the variance in the explosive energy versus pressure relationship, strong variability remains in the yield estimate. Today, numerical modeling techniques provide a basis to better understand the role of different factors describing the source and the atmosphere that influence propagation predictions. In this study, the effects of the source frequency and the stratospheric wind speed are simulated. In order to characterize fine-scale atmospheric structures which are excluded from the current atmospheric specifications, model predictions are further enhanced by the addition of perturbation terms. A theoretical attenuation relation is thus developed from massive numerical simulations using the Parabolic Equation method. Compared with previous studies, our approach provides a more realistic physical description of long-range infrasound propagation. We obtain a new relation combining a near-field and a far-field term, which account for the effects of both geometrical spreading and absorption. In the context of the future verification of the CTBT, the derived attenuation relation quantifies the spatial and temporal variability of the <span class="hlt">IMS</span> infrasound network performance in higher resolution, and will be helpful for the design and prioritizing maintenance of any arbitrary infrasound monitoring network.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_18 --> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27264676','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27264676"><span>Solubility of alkali metal halides in the ionic liquid [C4C1<span class="hlt">im</span>][OTf].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kuzmina, O; Bordes, E; Schmauck, J; Hunt, P A; Hallett, J P; Welton, T</p> <p>2016-06-28</p> <p>The solubilities of the metal halides LiF, LiCl, LiBr, LiI, NaF, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbCl, CsCl, CsI, were measured at temperatures ranging from 298.15 to 378.15 K in the ionic liquid 1-butyl-3-methylimidazolium trifluoromethanesulfonate ([C4C1<span class="hlt">im</span>][OTf]). Li(+), Na(+) and K(+) salts with anions matching the ionic liquid have also been investigated to determine how well these cations dissolve in [C4C1<span class="hlt">im</span>][OTf]. This study compares the influence of metal cation and halide anion on the solubility of salts within this ionic liquid. The highest solubility found was for iodide salts, and the lowest solubility for the three fluoride salts. There is no outstanding difference in the solubility of salts with matching anions in comparison to halide salts. The experimental data were correlated employing several phase equilibria models, including ideal mixtures, van't Hoff, the λh (Buchowski) equation, the modified Apelblat equation, and the non-random two-liquid model (NRTL). It was found that the van't Hoff model gave the best correlation results. On the basis of the experimental data the thermodynamic dissolution parameters (ΔH, ΔS, and ΔG) were determined for the studied systems together with computed gas phase metathesis parameters. Dissolution depends on the energy difference between enthalpies of fusion and dissolution of the solute salt. This demonstrates that overcoming the lattice energy of the solid matrix is the key to the solubility of inorganic salts in ionic liquids.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24473178','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24473178"><span>Collaterals at angiography and outcomes in the Interventional Management of Stroke (<span class="hlt">IMS</span>) III trial.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Liebeskind, David S; Tomsick, Thomas A; Foster, Lydia D; Yeatts, Sharon D; Carrozzella, Janice; Demchuk, Andrew M; Jovin, Tudor G; Khatri, Pooja; von Kummer, Ruediger; Sugg, Rebecca M; Zaidat, Osama O; Hussain, Syed I; Goyal, Mayank; Menon, Bijoy K; Al Ali, Firas; Yan, Bernard; Palesch, Yuko Y; Broderick, Joseph P</p> <p>2014-03-01</p> <p>Endovascular strategies provide unique opportunity to correlate angiographic measures of collateral circulation at the time of endovascular therapy. We conducted systematic analyses of collaterals at conventional angiography on recanalization, reperfusion, and clinical outcomes in the endovascular treatment arm of the Interventional Management of Stroke (<span class="hlt">IMS</span>) III trial. Prospective evaluation of angiographic collaterals was conducted via central review of subjects treated with endovascular therapy in <span class="hlt">IMS</span> III (n=331). Collateral grade before endovascular therapy was assessed with the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology scale, blinded to all other data. Statistical analyses investigated the association between collaterals with baseline clinical variables, angiographic measures of recanalization, reperfusion and clinical outcomes. Adequate views of collateral circulation to the ischemic territory were available in 276 of 331 (83%) subjects. Collateral grade was strongly related to both recanalization of the occluded arterial segment (P=0.0016) and downstream reperfusion (P<0.0001). Multivariable analyses confirmed that robust angiographic collateral grade was a significant predictor of good clinical outcome (modified Rankin Scale score≤2) at 90 days (P=0.0353), adjusted for age, history of diabetes mellitus, National Institutes of Health Stroke Scale strata, and Alberta Stroke Program Early CT Score. The relationship between collateral flow and clinical outcome may depend on the degree of reperfusion. More robust collateral grade was associated with better recanalization, reperfusion, and subsequent better clinical outcomes. These data, from the largest endovascular trial to date, suggest that collaterals are an important consideration in future trial design. http://www.clinicaltrials.gov. Unique identifier: NCT00359424.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..1912328H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..1912328H"><span>Re-establishment of the <span class="hlt">IMS</span> Hydroacoustic Station HA04, Crozet Islands, France.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Haralabus, Georgios; Stanley, Jerry; Zampolli, Mario; Grenard, Patrick; Nielsen, Peter; Le Bras, Ronan; Brown, David; Bittner, Paulina; Wang, Haijun; Gore, Jane; Amir, Menachem; Bereza, Slava</p> <p>2017-04-01</p> <p>The incorporation of the hydroacoustic station HA04, Crozet Islands, France, into the International Monitoring System (<span class="hlt">IMS</span>) of the Comprehensive Nuclear-Test-Ban Treaty Organisation (CTBTO) is a 17 year saga that had a happy ending on 29 December 2016. On that day, following a major engineering and logistical undertaking, the station was successfully installed. While still in its initial testing phase, HA04 sends continuously quality data at the International Data Centre (IDC), pending official certification and promotion to mainstream operational status. Similarly to most other cabled hydroacoustic stations in the <span class="hlt">IMS</span>, HA04 is comprised of two triplets of moored hydrophones deployed on both sides of Possession Island (Crozet Islands) sending uninterrupted data to a shore facility via submarine fiber optic cables. The designed frequency pass-band is 1 - 100 Hz. Data are relayed to Vienna via a shore based satellite link in real time. According to CTBTO's standard requirements, the design life of HA04 is at least 20 years, maintenance-free for the underwater system. An outline of the main phases of this project, highlights from the installation operations and examples of received hydroacoustic signals associated with recent underwater seismic activity in the Indian Ocean as well as vocalizations from marine mammals acquired by the new HA04 are presented here. HA04 is scheduled to be fully integrated into the operational platform of IDC in the next six months, which will enable registered researchers to access archived monitoring data and processing software, or via the National Data Centres (NDCs).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16718336','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16718336"><span>Influence of gamma irradiation on hydrophobic room-temperature ionic liquids [BuMe<span class="hlt">Im</span>]PF6 and [BuMe<span class="hlt">Im</span>](CF3SO2)2N.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Berthon, L; Nikitenko, S I; Bisel, I; Berthon, C; Faucon, M; Saucerotte, B; Zorz, N; Moisy, Ph</p> <p>2006-06-07</p> <p>Stability of neat hydrophobic Room-Temperature Ionic Liquids (RTIL) [BuMe<span class="hlt">Im</span>]X, where [BuMe<span class="hlt">Im</span>]+ is 1-butyl-3-methylimidazolium and X- is PF6-, and (CF3SO2)2N-, was studied under gamma radiolysis (137Cs) in an argon atmosphere and in air. It was found that the density, surface tension, and refraction index of RTILs are unchanged even by an absorbed dose of approximately 600 kGy. Studied RTILs exhibit considerable darkening when subjected to gamma irradiation. The light absorbance of ionic liquids increases linearly with the irradiation dose. Water has no influence on radiolytic darkening. A comparative study of [BuMe<span class="hlt">Im</span>]X and [Bu4N][Tf2N] leads to the conclusion that the formation of colored products is related to gamma radiolysis of the [BuMe<span class="hlt">Im</span>]+ cation. The radiolytic darkening kinetics of RTILs is influenced by the anions as follows: Cl- < (CF3SO2)2N- < PF6-. Electrospray ionization mass spectrometry and NMR analysis reveal the presence of nonvolatile radiolysis products at concentrations below 1 mol% for an absorbed dose exceeding 1200 kGy. Initial step of BuMe<span class="hlt">Im</span>+ cation radiolysis is the loss of the Bu* group, the H* atom from the 2 position on the imidazolium ring, and the H* atom from the butyl chain. Radiolysis of ionic liquid anions yields F* and CF3* from PF6- and [Tf2N]-, respectively. Recombinations of these primary products of radiolysis lead to various polymeric and acidic species.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=child%27s+AND+language&pg=4&id=EJ1037712','ERIC'); return false;" href="https://eric.ed.gov/?q=child%27s+AND+language&pg=4&id=EJ1037712"><span>Initial Efficacy of Project <span class="hlt">Im</span>PACT: A Parent-Mediated Social Communication Intervention for Young Children with ASD</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ingersoll, Brooke; Wainer, Allison</p> <p>2013-01-01</p> <p>Project <span class="hlt">Im</span>PACT is a parent-mediated social communication intervention for young children with ASD that was developed in community settings to encourage dissemination. A single-subject, multiple-baseline design was conducted across 8 preschoolers with ASD and their mothers to examine the efficacy of the model for improving parent intervention…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-10-29/pdf/2010-27370.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-10-29/pdf/2010-27370.pdf"><span>75 FR 66791 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-10-29</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on September 30, 2010, pursuant to Section... Act''), <span class="hlt">IMS</span> Global Learning Consortium, Inc. has filed written notifications simultaneously with the... KOREA; eChalk, New York, NY; Miami-Dade College--Virtual College, Miami, FL; National Labor...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MNRAS.468L.108H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MNRAS.468L.108H"><span>First evidence of external disc photoevaporation in a low mass star forming region: the case of <span class="hlt">IM</span> Lup</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Haworth, Thomas J.; Facchini, Stefano; Clarke, Cathie J.; Cleeves, L. Ilsedore</p> <p>2017-06-01</p> <p>We model the radiatively driven flow from <span class="hlt">IM</span> Lup - a large protoplanetary disc expected to be irradiated by only a weak external radiation field (at least 104 times lower than the ultraviolet field irradiating the Orion Nebula Cluster proplyds). We find that material at large radii (>400 au) in this disc is sufficiently weakly gravitationally bound that significant mass-loss can be induced. Given the estimated values of the disc mass and accretion rate, the viscous time-scale is long (˜10 Myr) so the main evolutionary behaviour for the first Myr of the disc's lifetime is truncation of the disc by photoevaporation, with only modest changes effected by viscosity. We also produce approximate synthetic observations of our models, finding substantial emission from the flow that can explain the CO halo observed about <span class="hlt">IM</span> Lup out to ≥1000 au. Solutions that are consistent with the extent of the observed CO emission generally imply that <span class="hlt">IM</span> Lup is still in the process of having its disc outer radius truncated. We conclude that <span class="hlt">IM</span> Lup is subject to substantial external photoevaporation, which raises the more general possibility that external irradiation of the largest discs can be of significant importance even in low mass star forming regions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-01-26/pdf/C1-2011-78.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-01-26/pdf/C1-2011-78.pdf"><span>76 FR 4723 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-01-26</p> <p>... Global Learning Consortium, Inc. Correction In notice document 2011-78 appearing on page 1460 the issue... Global Learning Consortium, Inc.'' should read ``<span class="hlt">IMS</span> Global Learning Consortium, Inc.''. 3. On the same page, in the third column, in the 15th and 16th lines, ``INS Global Learning Consortium,...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-03-24/pdf/2010-6268.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-03-24/pdf/2010-6268.pdf"><span>75 FR 14191 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-03-24</p> <p>... Global Learning Consortium, Inc. Notice is hereby given that, on February 16, 2010, pursuant to section 6... Act''), <span class="hlt">IMS</span> Global Learning Consortium Inc. has filed written notifications simultaneously with the..., CA have been added as parties to this venture. Also, LearnGauge, LLC, Okemos, MI; Inigral, Inc.,...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title5-vol2/pdf/CFR-2012-title5-vol2-sec894-304.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title5-vol2/pdf/CFR-2012-title5-vol2-sec894-304.pdf"><span>5 CFR 894.304 - Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-01-01</p> <p>... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation? 894.304 Section 894.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2014-title5-vol2/pdf/CFR-2014-title5-vol2-sec894-304.pdf','CFR2014'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2014-title5-vol2/pdf/CFR-2014-title5-vol2-sec894-304.pdf"><span>5 CFR 894.304 - Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2014&page.go=Go">Code of Federal Regulations, 2014 CFR</a></p> <p></p> <p>2014-01-01</p> <p>... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation? 894.304 Section 894.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title5-vol2/pdf/CFR-2011-title5-vol2-sec894-304.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title5-vol2/pdf/CFR-2011-title5-vol2-sec894-304.pdf"><span>5 CFR 894.304 - Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-01-01</p> <p>... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation? 894.304 Section 894.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2013-title5-vol2/pdf/CFR-2013-title5-vol2-sec894-304.pdf','CFR2013'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2013-title5-vol2/pdf/CFR-2013-title5-vol2-sec894-304.pdf"><span>5 CFR 894.304 - Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2013&page.go=Go">Code of Federal Regulations, 2013 CFR</a></p> <p></p> <p>2013-01-01</p> <p>... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation? 894.304 Section 894.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=single+AND+parents+AND+child+AND+development&id=EJ1037712','ERIC'); return false;" href="http://eric.ed.gov/?q=single+AND+parents+AND+child+AND+development&id=EJ1037712"><span>Initial Efficacy of Project <span class="hlt">Im</span>PACT: A Parent-Mediated Social Communication Intervention for Young Children with ASD</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ingersoll, Brooke; Wainer, Allison</p> <p>2013-01-01</p> <p>Project <span class="hlt">Im</span>PACT is a parent-mediated social communication intervention for young children with ASD that was developed in community settings to encourage dissemination. A single-subject, multiple-baseline design was conducted across 8 preschoolers with ASD and their mothers to examine the efficacy of the model for improving parent intervention…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2012-06-08/pdf/2012-13974.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2012-06-08/pdf/2012-13974.pdf"><span>77 FR 34069 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-<span class="hlt">IMS</span> Global...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2012-06-08</p> <p>... Antitrust Division Notice Pursuant to the National Cooperative Research and Production Act of 1993--<span class="hlt">IMS</span> Global Learning Consortium, Inc. Notice is hereby given that, on May 2, 2012, pursuant to Section 6(a) of the National Cooperative Research and Production Act of 1993, 15 U.S.C. 4301 et seq. (``the Act...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title5-vol2/pdf/CFR-2010-title5-vol2-sec894-304.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title5-vol2/pdf/CFR-2010-title5-vol2-sec894-304.pdf"><span>5 CFR 894.304 - Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation?</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-01-01</p> <p>... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Am I eligible to enroll if <span class="hlt">I'm</span> retired or receiving workers' compensation? 894.304 Section 894.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2014-title40-vol5/pdf/CFR-2014-title40-vol5-sec52-2348.pdf','CFR2014'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2014-title40-vol5/pdf/CFR-2014-title40-vol5-sec52-2348.pdf"><span>40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2014&page.go=Go">Code of Federal Regulations, 2014 CFR</a></p> <p></p> <p>2014-07-01</p> <p>... Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2013-title40-vol5/pdf/CFR-2013-title40-vol5-sec52-2348.pdf','CFR2013'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2013-title40-vol5/pdf/CFR-2013-title40-vol5-sec52-2348.pdf"><span>40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2013&page.go=Go">Code of Federal Regulations, 2013 CFR</a></p> <p></p> <p>2013-07-01</p> <p>... Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol5/pdf/CFR-2012-title40-vol5-sec52-2348.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol5/pdf/CFR-2012-title40-vol5-sec52-2348.pdf"><span>40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-07-01</p> <p>... Act Motor Vehicle Inspection and Maintenance (<span class="hlt">I/M</span>) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA569546','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA569546"><span>Enhancing the Contribution of the T-Stations of the <span class="hlt">IMS</span> Hydroacoustic Network to IDC Processing and Tsunami Warning</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2010-09-01</p> <p>the <span class="hlt">IMS</span> because of their potential ( deGroot -Hedlin, 2001) to detect water-borne signals from in-water explosions (H-phases) and crustal events (T...also gratefully acknowledged. REFERENCES deGroot -Hedlin, C. and Orcutt, J. (Eds) (2001). Monitoring the Comprehensive Nuclear-Test-Ban Treaty</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_19 --> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25870148','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25870148"><span>Influence of Language of Administration on <span class="hlt">Im</span>PACT Performance by Bilingual Spanish-English College Students.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lehman Blake, Margaret; Ott, Summer; Villanyi, Elizabeth; Kazhuro, Katia; Schatz, Philip</p> <p>2015-06-01</p> <p>Previous research has suggested that there are performance differences on the Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) battery related to language of administration, such that scores are higher with the English than the Spanish version of the battery. This study extended those findings in a within-subjects design, evaluating neurocognitive performance of 58 bilingual English-Spanish-speaking individuals who completed <span class="hlt">Im</span>PACT in both languages. Results revealed a significant multivariate effect of language of test administration, p < .01; partial η(2) = 0.23, with significantly better English language performance on Verbal Memory and Visual Motor Speed composite scores, but not Visual Memory, Reaction Time, or Total Symptom score. Results are discussed in relation to potential linguistic biases of the <span class="hlt">Im</span>PACT and functional language dominance that may contribute to the lower scores. These results extend previous findings and suggest a need for separate normative data for Spanish-speaking individuals completing the <span class="hlt">Im</span>PACT battery if baseline data are not present.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63973&keyword=dissociation&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89721137&CFTOKEN=39868979','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=63973&keyword=dissociation&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89721137&CFTOKEN=39868979"><span>EVALUATION OF CRYPTOSPORIDIUM OOCYST RECOVERY IN WATER BY EPA METHOD 1623 WITH A MODIFIED <span class="hlt">IMS</span> DISSOCIATION PROCEDURE</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>U.S.EPA Methods 1622 and 1623 are used for the detection of waterborne Cryptosporium. These methods consist of filtration, elution, purificaiton by immunomagnetic separation (<span class="hlt">IMS</span>), and microscopic analysis for oocysts stained by a fluorescent monoclonal antibody and counter stai...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..1913671H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..1913671H"><span>Using the <span class="hlt">IMS</span> infrasound network for the identification of mountain-associated waves and gravity waves hotspots</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hupe, Patrick; Ceranna, Lars; Pilger, Christoph; Le Pichon, Alexis</p> <p>2017-04-01</p> <p>The infrasound network of the International Monitoring System (<span class="hlt">IMS</span>) has been established for monitoring the atmosphere to detect violations of the Comprehensive nuclear-Test-Ban Treaty (CTBT). The <span class="hlt">IMS</span> comprises 49 certified infrasound stations which are globally distributed. Each station provides data for up to 16 years. Due to the uniform distribution of the stations, the <span class="hlt">IMS</span> infrasound network can be used to derive global information on atmospheric dynamics' features. This study focuses on mountain-associated waves (MAWs), i.e. acoustic waves in the frequency range between approximately 0.01 Hz and 0.05 Hz. MAWs can be detected in infrasound data by applying the Progressive Multi-Channel Correlation (PMCC) algorithm. As a result of triangulation, global hotspots of MAWs can be identified. Previous studies on gravity waves indicate that global hotspots of gravity waves are similar to those found for MAWs by using the PMCC algorithm. The objective of our study is an enhanced understanding of the excitation sources and of possible interactions between MAWs and gravity waves. Therefore, spatial and temporal correlation analyses will be performed. As a preceding step, we will present (seasonal) hotspots of MAWs as well as hotspots of gravity waves derived by the <span class="hlt">IMS</span> infrasound network.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23625285','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23625285"><span>Use of <span class="hlt">Im</span>PACT to diagnose minimal hepatic encephalopathy: an accurate, practical, user-friendly internet-based neuropsychological test battery.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tsushima, Matthew; Tsushima, William; Tsushima, Vincent; Lim, Nelson; Madrigal, Erika; Jackson, Christian; Mendler, Michel Henry</p> <p>2013-09-01</p> <p>An effective, user-friendly neurocognitive test to diagnose minimal hepatic encephalopathy (MHE) is needed. Immediate Post-concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) is a brief, validated, Web-based, neuropsychological test battery resulting in four composite scores [Verbal Memory (VrbM), Visual Memory, Visual Motor Speed (VMS), Reaction Time (RT)]. We compared <span class="hlt">Im</span>PACT to traditional paper-and-pencil tests in patients at risk for MHE versus controls. Ninety cirrhotic patients with no history of overt hepatic encephalopathy were compared with 131 controls on standard psychometric tests (SPT) [Trail Making Test-A, Trail Making Test-B, Digit Symbol Test], 4 <span class="hlt">Im</span>PACT composite scores, and the Sickness Impact Profile (SIP). MHE+ was defined by a score 2 SD below the normative mean on at least one of the SPT. <span class="hlt">Im</span>PACT (<span class="hlt">Im</span>P+) scores of patients were defined as 2 SD from the control mean. Cirrhotic patients scored more poorly than controls on 3/4 of <span class="hlt">Im</span>PACT scores: VrbM (78.88 vs. 71.37, p<0.001), VMS (26.47 vs. 22.68, p<0.001) and RT (0.89 vs. 1.00, p<0.01), as well as on all 3 SPT. Of the 90 cirrhotics, 16 (18%) were MHE+, who performed more poorly (p<0.001) than patients without MHE on VrbM (58.13 vs. 74.19), VMS (16.77 vs. 23.95) and RT (1.24 vs. 0.95). Of the 90 cirrhotics, 25 (27.8%) were <span class="hlt">Im</span>P+. MHE+ and <span class="hlt">Im</span>P+ patients had increased SIP scores versus controls (p<0.001). Compared to paper-and-pencil testing, <span class="hlt">Im</span>PACT provides a brief, user-friendly, neuropsychological evaluation of MHE. <span class="hlt">Im</span>PACT could become a new standard for MHE diagnosis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28561095','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28561095"><span>Metal carbonate complexes formed through the capture of ambient O2 and CO2 by elemental metals in 1-methylimidazole: molecular Cu(CO3)(Me<span class="hlt">Im</span>)3 and polymeric M(CO3)(Me<span class="hlt">Im</span>)2·2H2O (M = Co, Zn).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vaid, Thomas P; Kelley, Steven P; Rogers, Robin D</p> <p>2017-07-18</p> <p>When immersed in 1-methylimidazole, the metals copper, zinc, and cobalt will react with ambient dioxygen and carbon dioxide to yield the blue-green molecular complex Cu(CO3)(Me<span class="hlt">Im</span>)3 and the pair of isostructural polymeric complexes Zn(CO3)(Me<span class="hlt">Im</span>)2·2H2O and Co(CO3)(Me<span class="hlt">Im</span>)2·2H2O, respectively.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.S31A2714G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.S31A2714G"><span>The Global Detection Capability of the <span class="hlt">IMS</span> Seismic Network in 2013 Inferred from Ambient Seismic Noise Measurements</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gaebler, P. J.; Ceranna, L.</p> <p>2016-12-01</p> <p>All nuclear explosions - on the Earth's surface, underground, underwater or in the atmosphere - are banned by the Comprehensive Nuclear-Test-Ban Treaty (CTBT). As part of this treaty, a verification regime was put into place to detect, locate and characterize nuclear explosion testings at any time, by anyone and everywhere on the Earth. The International Monitoring System (<span class="hlt">IMS</span>) plays a key role in the verification regime of the CTBT. Out of the different monitoring techniques used in the <span class="hlt">IMS</span>, the seismic waveform approach is the most effective technology for monitoring nuclear underground testing and to identify and characterize potential nuclear events. This study introduces a method of seismic threshold monitoring to assess an upper magnitude limit of a potential seismic event in a certain given geographical region. The method is based on ambient seismic background noise measurements at the individual <span class="hlt">IMS</span> seismic stations as well as on global distance correction terms for body wave magnitudes, which are calculated using the seismic reflectivity method. From our investigations we conclude that a global detection threshold of around mb 4.0 can be achieved using only stations from the primary seismic network, a clear latitudinal dependence for the detection thresholdcan be observed between northern and southern hemisphere. Including the seismic stations being part of the auxiliary seismic <span class="hlt">IMS</span> network results in a slight improvement of global detection capability. However, including wave arrivals from distances greater than 120 degrees, mainly PKP-wave arrivals, leads to a significant improvement in average global detection capability. In special this leads to an improvement of the detection threshold on the southern hemisphere. We further investigate the dependence of the detection capability on spatial (latitude and longitude) and temporal (time) parameters, as well as on parameters such as source type and percentage of operational <span class="hlt">IMS</span> stations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002PhDT........67J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002PhDT........67J"><span>Vergleich von rekombinanten Vaccinia- und DNA-Vektoren zur Tumorimmuntherapie <span class="hlt">im</span> C57BL/6-Mausmodell</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Johnen, Heiko</p> <p>2002-10-01</p> <p>In der vorliegenden Arbeit wurden Tumorimpfstoffe auf der Basis des Plasmid-Vektors pCI, modified vaccinia virus Ankara (MVA) und MVA-infizierten dendritischen Zellen entwickelt und durch Sequenzierung, Western blotting und durchflußzytometrische Analyse überprüft. Die in vivo Wirksamkeit der Vakzinen wurde in verschiedenen Tumormodellen in C57BL/6 Mäusen verglichen. Die auf dem eukaryotischen Expressionsvektor pCI basierende DNA-Vakzinierung induzierte einen sehr wirksamen, antigenspezifischen und langfristigen Schutz vor Muzin, CEA oder beta-Galactosidase exprimierenden Tumoren. Eine MVA-Vakzinierung bietet in den in dieser Arbeit durchgeführten Tumormodellen keinen signifikanten Schutz vor Muzin oder beta-Galactosidase exprimierenden Tumoren. Sowohl humane, als auch murine in vitro generierte dendritische Zellen lassen sich mit MVA – <span class="hlt">im</span> Vergleich zu anderen viralen Vektoren – sehr gut infizieren. Die Expressionsrate der eingefügten Gene ist aber gering <span class="hlt">im</span> Vergleich zur Expression in permissiven Wirtszellen des Virus (embryonale Hühnerfibroblasten). Es konnte gezeigt werden, daß eine MVA-Infektion dendritischer Zellen ähnliche Auswirkungen auf den Reifezustand humaner und muriner dendritischer Zellen hat, wie eine Infektion mit replikationskompetenten Vakzinia-Stämmen, und außerdem die Hochregulation von CD40 während der terminalen Reifung von murinen dendritischen Zellen inhibiert wird. Die während der langfristigen in vitro Kultur auf CEF-Zellen entstandenen Deletionen <span class="hlt">im</span> MVA Genom führten zu einer starken Attenuierung und dem Verlust einiger Gene, die immunmodulatorische Proteine kodieren, jedoch nicht zu einer Verminderung des zytopathischen Effekts in dendritischen Zellen. Die geringe Expressionsrate und die beobachtete Inhibition der Expression kostimulatorischer Moleküle auf dendritischen Zellen kann für eine wenig effektive Induktion einer Immunantwort in MVA vakzinierten Tieren durch cross priming oder die direkte Infektion</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24837075','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24837075"><span>Biosynthesis of wyosine derivatives in tRNA(Phe) of Archaea: role of a remarkable bifunctional tRNA(Phe):m1G/<span class="hlt">im</span>G2 methyltransferase.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Urbonavičius, Jaunius; Meškys, Rolandas; Grosjean, Henri</p> <p>2014-06-01</p> <p>The presence of tricyclic wyosine derivatives 3'-adjacent to anticodon is a hallmark of tRNA(Phe) in eukaryotes and archaea. In yeast, formation of wybutosine (yW) results from five enzymes acting in a strict sequential order. In archaea, the intermediate compound <span class="hlt">im</span>G-14 (4-demethylwyosine) is a target of three different enzymes, leading to the formation of distinct wyosine derivatives (yW-86, <span class="hlt">im</span>G, and <span class="hlt">im</span>G2). We focus here on a peculiar methyltransferase (aTrm5a) that catalyzes two distinct reactions: N(1)-methylation of guanosine and C(7)-methylation of <span class="hlt">im</span>G-14, whose function is to allow the production of isowyosine (<span class="hlt">im</span>G2), an intermediate of the 7-methylwyosine (mimG) biosynthetic pathway. Based on the formation of mesomeric forms of <span class="hlt">im</span>G-14, a rationale for such dual enzymatic activities is proposed. This bifunctional tRNA:m(1)G/<span class="hlt">im</span>G2 methyltransferase, acting on two chemically distinct guanosine derivatives located at the same position of tRNA(Phe), is unique to certain archaea and has no homologs in eukaryotes. This enzyme here referred to as Taw22, probably played an important role in the emergence of the multistep biosynthetic pathway of wyosine derivatives in archaea and eukaryotes.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27693914','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27693914"><span>Specific interaction of <span class="hlt">IM</span>30/Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Heidrich, Jennifer; Thurotte, Adrien; Schneider, Dirk</p> <p>2017-04-01</p> <p>The photosynthetic light reaction takes place within the thylakoid membrane system in cyanobacteria and chloroplasts. Besides its global importance, the biogenesis, maintenance and dynamics of this membrane system are still a mystery. In the last two decades, strong evidence supported the idea that these processes involve <span class="hlt">IM</span>30, the inner membrane-associated protein of 30kDa, a protein also known as the vesicle-inducing protein in plastids 1 (Vipp1). Even though we just only begin to understand the precise physiological function of this protein, it is clear that interaction of <span class="hlt">IM</span>30 with membranes is crucial for biogenesis of thylakoid membranes. Here we summarize and discuss forces guiding <span class="hlt">IM</span>30-membrane interactions, as the membrane properties as well as the oligomeric state of <span class="hlt">IM</span>30 appear to affect proper interaction of <span class="hlt">IM</span>30 with membrane surfaces. Interaction of <span class="hlt">IM</span>30 with membranes results in an altered membrane structure and can finally trigger fusion of adjacent membranes, when Mg(2+) is present. Based on recent results, we finally present a model summarizing individual steps involved in <span class="hlt">IM</span>30-mediated membrane fusion. This article is part of a Special Issue entitled: Lipid order/lipid defects and lipid-control of protein activity edited by Dirk Schneider. Copyright © 2016 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100021350','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100021350"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa and the Other Galilean Moons</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Sittler, Edward; Cooper, John; Hartle, Richard; Lipatov, Alexander; Mahaffy, Paul; Paterson, William; Pachalidis, Nick; Coplan, Mike; Cassidy, Tim</p> <p>2010-01-01</p> <p>NASA and ESA are planning the joint Europa Jupiter System Mission (EJSM) to the Jupiter system with specific emphasis to Europa and Ganymede, respectively. The Japanese Space Agency is also planning an orbiter mission to explore Jupiter's magnetosphere and the Galilean satellites. For NASA's Jupiter Europa Orbiter (JEO) we are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) with two main goals which can also be applied to the other Galilean moons, 1) measure the plasma interaction between Europa and Jupiter's magnetosphere and 2) infer the 4 pi surface composition to trace elemental and significant isotopic levels. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa's sub-surface ocean, while the second gives information about transfer of material between the Galilean moons, and between the moon surfaces and subsurface layers putatively including oceans. The measurement of the interactions for all the Galilean moons can be used to trace the in situ ion measurements of pickup ions back to either Europa's or Ganymede's surface from the respectively orbiting spacecraft. The <span class="hlt">IMS</span> instrument, being developed under NASA's Astrobiology Instrument Development Program, would maximally achieve plasma measurement requirements for JEO and EJSM while moving forward our knowledge of Jupiter system composition and source processes to far higher levels than previously envisaged. The composition of the global surfaces of Europa and Ganymede can be inferred from the measurement of ejected neutrals and pick-up ions using at minimum an in situ payload including MAG and <span class="hlt">IMS</span> also fully capable of meeting Level 1 mission requirements for ocean detection and survey. Elemental and isotopic analysis of potentially extruded oceanic materials at the moon surfaces would further support the ocean objectives. These measurements should be made from a polar orbiting spacecraft about Europa or Ganymede at height 100 km. The ejecta produced by</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..12.7451S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..12.7451S"><span>Plasma <span class="hlt">IMS</span> Composition Measurements for Europa and the Other Galilean Moons</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sittler, Edward; Cooper, John; Hartle, Richard; Lipatov, Alexander; Mahaffy, Paul; Paterson, William; Pachalidis, Nick; Coplan, Mike; Cassidy, Tim</p> <p>2010-05-01</p> <p>NASA and ESA are planning the joint Europa Jupiter System Mission (EJSM) to the Jupiter system with specific emphasis to Europa and Ganymede, respectively. The Japanese Space Agency is also planning an orbiter mission to explore Jupiter's magnetosphere and the Galilean satellites. For NASA's Jupiter Europa Orbiter (JEO) we are developing the 3D Ion Mass Spectrometer (<span class="hlt">IMS</span>) with two main goals which can also be applied to the other Galilean moons, 1) measure the plasma interaction between Europa and Jupiter's magnetosphere and 2) infer the 4? surface composition to trace elemental [1] and significant isotopic levels. The first goal supports the magnetometer (MAG) measurements, primarily directed at detection of Europa's sub-surface ocean, while the second gives information about transfer of material between the Galilean moons, and between the moon surfaces and subsurface layers putatively including oceans. The measurement of the interactions for all the Galilean moons can be used to trace the in situ ion measurements of pickup ions back to either Europa's or Ganymede's surface from the respectively orbiting spacecraft. The <span class="hlt">IMS</span> instrument, being developed under NASA's Astrobiology Instrument Development Program, would maximally achieve plasma measurement requirements for JEO and EJSM while moving forward our knowledge of Jupiter system composition and source processes to far higher levels than previously envisaged. The composition of the global surfaces of Europa and Ganymede can be inferred from the measurement of ejected neutrals and pick-up ions using at minimum an in situ payload including MAG and <span class="hlt">IMS</span> also fully capable of meeting Level 1 mission requirements for ocean detection and survey. Elemental and isotopic analysis of potentially extruded oceanic materials at the moon surfaces would further support the ocean objectives. These measurements should be made from a polar orbiting spacecraft about Europa or Ganymede at height ~ 100 km. The ejecta produced by</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JSeis.tmp...56A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JSeis.tmp...56A"><span>Study of seismicity in the NW Himalaya and adjoining regions using <span class="hlt">IMS</span> network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ali, Sherif M.; Shanker, D.</p> <p>2016-08-01</p> <p>The Reviewed Event Bulletin (REB) of the International Data Center (IDC) has been used in order to investigate the seismicity of the Northwest Himalaya and its neighboring region for the time period June 1999 to March 2015 within the geographical coordinates 25-40° N latitude and 65-85° E longitude. We have used a very precisely located earthquake dataset recorded by the International Monitoring System (<span class="hlt">IMS</span>) Network containing 7,583 events with body wave magnitudes from 2.5 to 6.3. The study area has been subdivided into six regions based on the Flinn-Engdahl (F-E) seismic and geographical regionalization scheme, which was used as the region classifications of the International Data Center catalog. The examined region includes NW India, Pakistan, Nepal, Xizang, Kashmir, and Hindukush. For each region, Magnitudes of completeness (Mc) and Gutenberg-Richter (GR) recurrence parameters (a and b values) have been estimated. The Gutenberg-Richter analysis is preceded by an overview of the seismotectonics of the study area. The obtained Mc values vary from 3.5 to 3.9. The lower value of Mc was found mainly in Xizang region whereas the higher Mc threshold is evident in Pakistan region. However, the b values vary from 1.19 to 1.48. The lowest b value is recorded in Xizang region, which is mostly related to the Main Karakoram Thrust (MKT) fault, whereas the highest b values are recorded in NW India and Kashmir regions, which are mostly related to the Main Frontal Thrust (MFT) fault. The REB for the selected period has been compared to the most renowned bulletin of global seismicity, namely that issued by the National Earthquake Information Center (NEIC) of the United States Geological Survey (USGS). A study of 4,821 events recorded by USGS in the study region indicates that about 36 % of seismic events were missed and the catalog is considered as complete for events with magnitudes ≥4.0. However, both a and b values are obviously higher than those of <span class="hlt">IMS</span> catalog. The a</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JSeis..21..317A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JSeis..21..317A"><span>Study of seismicity in the NW Himalaya and adjoining regions using <span class="hlt">IMS</span> network</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ali, Sherif M.; Shanker, D.</p> <p>2017-03-01</p> <p>The Reviewed Event Bulletin (REB) of the International Data Center (IDC) has been used in order to investigate the seismicity of the Northwest Himalaya and its neighboring region for the time period June 1999 to March 2015 within the geographical coordinates 25-40° N latitude and 65-85° E longitude. We have used a very precisely located earthquake dataset recorded by the International Monitoring System (<span class="hlt">IMS</span>) Network containing 7,583 events with body wave magnitudes from 2.5 to 6.3. The study area has been subdivided into six regions based on the Flinn-Engdahl (F-E) seismic and geographical regionalization scheme, which was used as the region classifications of the International Data Center catalog. The examined region includes NW India, Pakistan, Nepal, Xizang, Kashmir, and Hindukush. For each region, Magnitudes of completeness (Mc) and Gutenberg-Richter (GR) recurrence parameters ( a and b values) have been estimated. The Gutenberg-Richter analysis is preceded by an overview of the seismotectonics of the study area. The obtained Mc values vary from 3.5 to 3.9. The lower value of Mc was found mainly in Xizang region whereas the higher Mc threshold is evident in Pakistan region. However, the b values vary from 1.19 to 1.48. The lowest b value is recorded in Xizang region, which is mostly related to the Main Karakoram Thrust (MKT) fault, whereas the highest b values are recorded in NW India and Kashmir regions, which are mostly related to the Main Frontal Thrust (MFT) fault. The REB for the selected period has been compared to the most renowned bulletin of global seismicity, namely that issued by the National Earthquake Information Center (NEIC) of the United States Geological Survey (USGS). A study of 4,821 events recorded by USGS in the study region indicates that about 36 % of seismic events were missed and the catalog is considered as complete for events with magnitudes ≥4.0. However, both a and b values are obviously higher than those of <span class="hlt">IMS</span> catalog. The a</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27273458','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27273458"><span>The importance of polarizability: comparison of models of carbon disulphide in the ionic liquids [C1C1<span class="hlt">im</span>][NTf2] and [C4C1<span class="hlt">im</span>][NTf2].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lynden-Bell, Ruth M; Quitevis, Edward L</p> <p>2016-06-28</p> <p>The local environment of CS2 and in solution in two ionic liquids ([C1C1<span class="hlt">im</span>][NTf2] and [C4C1<span class="hlt">im</span>][NTf2]) are investigated by atomistic simulation and compared with that in neat CS2. The intermolecular vibrational densities of states of CS2 are calculated and compared with experimental OHD-RIKES spectra. The fair agreement of the results from solutions but poor agreement of the results from neat CS2 suggest that while collective effects are unimportant in solutions, they have a major effect on the OHD-RIKES spectrum of neat CS2. Comparing polarizable and unpolarizable models for CS2 emphasizes the importance of polarizability in determining local structure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18826215','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18826215"><span>Magnetic spongelike behavior of 3D ferrimagnetic {[Mn(II)(<span class="hlt">im</span>H)]2[Nb(IV)(CN)8]}n with Tc = 62 K.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pinkowicz, Dawid; Podgajny, Robert; Bałanda, Maria; Makarewicz, Magdalena; Gaweł, Bartłomiej; Łasocha, Wiesław; Sieklucka, Barbara</p> <p>2008-11-03</p> <p>Fully reversible room temperature dehydration of 3D {Mn(II)2(<span class="hlt">im</span>H)2(H2O)4[Nb(IV)(CN)8] x 4 H2O}n (1; <span class="hlt">im</span>H = imidazole) of Tc = 25 K results in the formation of 3D ferrimagnet {[Mn(II)(<span class="hlt">im</span>H)]2[Nb(IV)(CN)8]}n (2), with Tc = 62 K, the highest ever known for octacyanometalate-based compounds. The dramatic magnetostructural modifications in 2 provide the first example of magnetic spongelike behavior in an octacyanometallate-based assembly.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JASMS.tmp...53O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JASMS.tmp...53O"><span>The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-<span class="hlt">IMS</span>)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>O'Rourke, Matthew B.; Raymond, Benjamin B. A.; Padula, Matthew P.</p> <p>2017-03-01</p> <p>Matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-<span class="hlt">IMS</span>) is a technique that has seen a sharp rise in both use and development. Despite this rapid adoption, there have been few thorough investigations into the actual physical mechanisms that underlie the acquisition of <span class="hlt">IMS</span> images. We therefore set out to characterize the effect of <span class="hlt">IMS</span> laser ablation patterns on the surface of a sample. We also concluded that the governing factors that control spatial resolution have not been correctly defined and therefore propose a new definition of resolution.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014JPS...265...36M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014JPS...265...36M"><span>The Na[FSA]-[C2C1<span class="hlt">im</span>][FSA] (C2C1<span class="hlt">im</span>+:1-ethyl-3-methylimidazolium and FSA-:bis(fluorosulfonyl)amide) ionic liquid electrolytes for sodium secondary batteries</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Matsumoto, Kazuhiko; Hosokawa, Takafumi; Nohira, Toshiyuki; Hagiwara, Rika; Fukunaga, Atsushi; Numata, Koma; Itani, Eiko; Sakai, Shoichiro; Nitta, Koji; Inazawa, Shinji</p> <p>2014-11-01</p> <p>Physical and electrochemical properties of the Na[FSA]-[C2C1<span class="hlt">im</span>][FSA] (C2C1<span class="hlt">im</span>+:1-ethyl-3-methylimidazolium and FSA-:bis(fluorosulfonyl)amide) ionic liquids have been investigated in view of their application as electrolytes for sodium secondary batteries operating in a wide temperature range. The Na[FSA]-[C2C1<span class="hlt">im</span>][FSA] ionic liquids in the range of 0.0 ≤ x(Na[FSA]) ≤ 0.5 are in the liquid state at room temperature, where x(Na[FSA]) is the mole fraction of Na[FSA]. In the case of x(Na[FSA]) = 0.3, the ionic conductivity, viscosity, and electrochemical window at 298 K are 5.4 mS cm-1, 78 mPa s, and 5.1 V, respectively. Sodium metal deposition/dissolution test in the ionic liquid at x(Na[FSA]) = 0.3 resulted in average cycle efficiencies of 69% and 96% at 298 K and 363 K, respectively, at a current density of 1.0 mA cm-2.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20000109957&hterms=dinosaur&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Ddinosaur','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20000109957&hterms=dinosaur&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Ddinosaur"><span>The Hummingbird GC-<span class="hlt">IMS</span>: In Situ Analysis of a Cometary Nucleus</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Carle, Glenn C.; Cohen, Martin J.; Wernlund, Roger F.; Stimac, Robert M.; Takeuchi, Norishige; DeVincenzi, Donald L. (Technical Monitor)</p> <p>2000-01-01</p> <p>Comets are of enormous scientific interest for many reasons. They are primitive bodies that date back to the earliest stages of solar system formation and, because of their small size and because they have been stored in the outer reaches of the solar system, their pristine nature has been preserved better than for any other class of body. They are extremely rich in highly volatile elements, many in the form of ices, and are richer in organic matter than any other known solar system body. It is strongly suspected that in addition to their content of primordial solar nebular material, they also incorporate unprocessed matter from the interstellar medium. Impacts by comets occur onto all the planets and satellites, often with major consequences (e.g., the dinosaur extinction event at the KIT boundary), or sometimes just providing a spectacular cosmic event (e.g., the collision of comet Shoemaker-Levy 9 with Jupiter). A mission to analyze a cometary nucleus must be capable of detecting and identifying over 30 molecular species among several different chemical groups. The Hummingbird Mission will rendezvous with, orbit, characterize, and make multiple descents to the nucleus of a comet. Hummingbird will employ a Gas Chromatograph - Ion Mobility Spectrometer (GC-<span class="hlt">IMS</span>) as part-of a suite of sophisticated instruments for a comprehensive in situ elemental, molecular, and isotopic analysis of the comet.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016SPIE10029E..1LW','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016SPIE10029E..1LW"><span>Performance analysis of passive optical network systems based on the <span class="hlt">IM</span>/DD OFDM modulation technique</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wchir, Besma; Ben Abdallah, Abderrazek; Mhatli, Sofien; Jarajreh, Mutsam; Yang, Sigang; Attia, Rabah</p> <p>2016-11-01</p> <p>Motivated by the robust immunity to interference as well as the higher spectrum efficiency, Orthogonal Frequency Division Multiplexing (OFDM) has been widely considered as one of the strongest contenders for high-speed Next- Generation Passive Optical Networks (NG-PONs), which satisfies the huge surge in demand for high-speed broadband services. In the other hand, OFDM systems suffer from a high Peak-to-Average Power Ratio (PAPR) at the transmitted signal resulting in signal degradation. The simplest method to deal with the PAPR problem consists in applying deliberate clipping to the transmitted signal which significantly reduces the requirement of the received optical power. In this paper, an analytical evaluation for the performance of an <span class="hlt">IM</span>/DD optical OFDM system is shown, this is while accounting for clipping distortion and quantification noise caused by the limited bit resolution of DAC converter. Moreover, the paper demonstrates that applying digital signal restoration at the system receiver enables further improvements in the system performances in terms of enhanced effective Signal-to-Noise Ratio (SNR) and reduced optical power that is required to achieve specified Bit-Error-Rate (BER).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011JASMS..22.1602B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011JASMS..22.1602B"><span>Biologically-Inspired Peptide Reagents for Enhancing <span class="hlt">IMS</span>-MS Analysis of Carbohydrates</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bohrer, Brian C.; Clemmer, David E.</p> <p>2011-09-01</p> <p>The binding properties of a peptidoglycan recognition protein are translated via combinatorial chemistry into short peptides. Non-adjacent histidine, tyrosine, and arginine residues in the protein's binding cleft that associate specifically with the glycan moiety of a peptidoglycan substrate are incorporated into linear sequences creating a library of 27 candidate tripeptide reagents (three possible residues permutated across three positions). Upon electrospraying the peptide library and carbohydrate mixtures, some noncovalent complexes are observed. The binding efficiencies of the peptides vary according to their amino acid composition as well as the disaccharide linkage and carbohydrate ring-type. In addition to providing a charge-carrier for the carbohydrate, peptide reagents can also be used to differentiate carbohydrate isomers by ion mobility spectrometry. The utility of these peptide reagents as a means of enhancing ion mobility analysis of carbohydrates is illustrated by examining four glucose-containing disaccharide isomers, including a pair that is not resolved by ion mobility alone. The specificity and stoichiometry of the peptide-carbohydrate complexes are also investigated. Trihistidine demonstrates both suitable binding efficiency and successful resolution of disaccharides isomers, suggesting it may be a useful reagent in <span class="hlt">IMS</span> analyses of carbohydrates.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_20 --> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014NatCh...6...65B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014NatCh...6...65B"><span>Discrimination of epimeric glycans and glycopeptides using <span class="hlt">IM</span>-MS and its potential for carbohydrate sequencing</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Both, P.; Green, A. P.; Gray, C. J.; Šardzík, R.; Voglmeir, J.; Fontana, C.; Austeri, M.; Rejzek, M.; Richardson, D.; Field, R. A.; Widmalm, G.; Flitsch, S. L.; Eyers, C. E.</p> <p>2014-01-01</p> <p>Mass spectrometry is the primary analytical technique used to characterize the complex oligosaccharides that decorate cell surfaces. Monosaccharide building blocks are often simple epimers, which when combined produce diastereomeric glycoconjugates indistinguishable by mass spectrometry. Structure elucidation frequently relies on assumptions that biosynthetic pathways are highly conserved. Here, we show that biosynthetic enzymes can display unexpected promiscuity, with human glycosyltransferase pp-α-GanT2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgalactosamine, leading to the synthesis of epimeric glycopeptides in vitro. Ion-mobility mass spectrometry (<span class="hlt">IM</span>-MS) was used to separate these structures and, significantly, enabled characterization of the attached glycan based on the drift times of the monosaccharide product ions generated following collision-induced dissociation. Finally, ion-mobility mass spectrometry following fragmentation was used to determine the nature of both the reducing and non-reducing glycans of a series of epimeric disaccharides and the branched pentasaccharide Man3 glycan, demonstrating that this technique may prove useful for the sequencing of complex oligosaccharides.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/10183040','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/10183040"><span>Proposed <span class="hlt">IMS</span> infrastructure improvement project, Seward, Alaska. Final environmental impact statement</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Not Available</p> <p>1994-09-01</p> <p>This Environmental Impact Statement (EIS) examines a proposal for improvements at the existing University of Alaska, Fairbanks, Institute of Marine Science (<span class="hlt">IMS</span>), Seward Marine Center. The Exxon Valdez Oil Spill (EVOS) Trustee Council is proposing to improve the existing research infrastructure to enhance the EVOS Trustee Council`s capabilities to study and rehabilitate marine mammals, marine birds, and the ecosystem injured by the Exxon Valdez oil spill. The analysis in this document focuses on the effects associated with construction and operation of the proposed project and its proposed alternatives. The EIS gives a detailed description of all major elements of the proposed project and its alternatives; identifies resources of major concern that were raised during the scoping process; describes the environmental background conditions of those resources; defines and analyzes the potential effects of the proposed project and its alternatives on these conditions; and identifies mitigating measures that are part of the project design as well as those proposed to minimize or reduce the adverse effects. Included in the EIS are written and oral comments received during the public comment period.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3426848','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3426848"><span><span class="hlt">im</span>DEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Grapov, Dmitry; Newman, John W.</p> <p>2012-01-01</p> <p>Summary: Interactive modules for Data Exploration and Visualization (<span class="hlt">im</span>DEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data through a user-friendly interface. Individual modules enables interactive and dynamic analyses of large data by interfacing R's multivariate statistics and highly customizable visualizations with the spreadsheet environment, aiding robust inferences and generating information-rich data visualizations. This tool provides access to multiple comparisons with false discovery correction, hierarchical clustering, principal and independent component analyses, partial least squares regression and discriminant analysis, through an intuitive interface for creating high-quality two- and a three-dimensional visualizations including scatter plot matrices, distribution plots, dendrograms, heat maps, biplots, trellis biplots and correlation networks. Availability and implementation: Freely available for download at http://sourceforge.net/projects/imdev/. Implemented in R and VBA and supported by Microsoft Excel (2003, 2007 and 2010). Contact: John.Newman@ars.usda.gov Supplementary Information: Installation instructions, tutorials and users manual are available at http://sourceforge.net/projects/imdev/. PMID:22815358</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20000109957&hterms=pcp&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dpcp','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20000109957&hterms=pcp&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dpcp"><span>The Hummingbird GC-<span class="hlt">IMS</span>: In Situ Analysis of a Cometary Nucleus</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Carle, Glenn C.; Cohen, Martin J.; Wernlund, Roger F.; Stimac, Robert M.; Takeuchi, Norishige; DeVincenzi, Donald L. (Technical Monitor)</p> <p>2000-01-01</p> <p>Comets are of enormous scientific interest for many reasons. They are primitive bodies that date back to the earliest stages of solar system formation and, because of their small size and because they have been stored in the outer reaches of the solar system, their pristine nature has been preserved better than for any other class of body. They are extremely rich in highly volatile elements, many in the form of ices, and are richer in organic matter than any other known solar system body. It is strongly suspected that in addition to their content of primordial solar nebular material, they also incorporate unprocessed matter from the interstellar medium. Impacts by comets occur onto all the planets and satellites, often with major consequences (e.g., the dinosaur extinction event at the KIT boundary), or sometimes just providing a spectacular cosmic event (e.g., the collision of comet Shoemaker-Levy 9 with Jupiter). A mission to analyze a cometary nucleus must be capable of detecting and identifying over 30 molecular species among several different chemical groups. The Hummingbird Mission will rendezvous with, orbit, characterize, and make multiple descents to the nucleus of a comet. Hummingbird will employ a Gas Chromatograph - Ion Mobility Spectrometer (GC-<span class="hlt">IMS</span>) as part-of a suite of sophisticated instruments for a comprehensive in situ elemental, molecular, and isotopic analysis of the comet.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/5613415','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/5613415"><span>Mechanical characterization of <span class="hlt">IM</span>7/8551-7 carbon/epoxy under biaxial stress: (Final report)</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Colvin, G.E. Jr.; Swanson, S.R.</p> <p>1987-11-13</p> <p>This is the final report on an investigation to evaluate the mechanical response of Hercules <span class="hlt">IM</span>7/8551-7 carbon/epoxy, which is a high strength, high elongation fiber and a high toughness resin system used in a prepreg form. The material characterization involved testing both laminate and lamina forms under a wide range of biaxial stress states. Tubular specimens were employed that have been designed to eliminate undesirable end effects, permitting uniform stress states to be achieved. Quasi-isotropic (90/+-45/0)/sub ns/laminates and (90)/sub 16T/ lamina specimens were loaded under combinations of internal pressure, axial load, and torsion. Both stiffness and strength data were obtained under these multiaxial stress conditions. The measured laminate stiffnesses correlated well using classical laminated plate theory, and that laminate failure occurred in the two separate modes of matrix cracking and fiber failure. Like the previously examined carbon/epoxy systems, laminate failure could be predicted by using a fiber failure criterion to identify the critical plies and critical load levels. It was found that either maximum fiber stress or fiber direction strain could be used as a failure criterion on a ply level. 16 refs., 10 figs., 3 tabs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19900064172&hterms=cyanide&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dcyanide','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19900064172&hterms=cyanide&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dcyanide"><span>Giotto <span class="hlt">IMS</span> measurements of the production rate of hydrogen cyanide in the coma of Comet Halley</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Ip, W.-H.; Balsiger, H.; Geiss, J.; Goldstein, B. E.; Kettmann, G.</p> <p>1990-01-01</p> <p>The ion composition measurements in the ionosphere of Comet Halley by the ion mass spectrometer (<span class="hlt">IMS</span>) experiment on the Giotto spacecraft are used to estimate the relative abundance of HCN. From a comparison of the normalized number density of ions with mass-to-charge (M/q) ratio of 28 AMU/e with steady-state photochemical models, it can be determined that the production rate of HCN directly from the central nucleus is Q(HCN) is less than about 0.0002 Q(H2O) at the time of Giotto encounter. The related photochemical- model calculations also indicate that Q(NH3)/Q(H2O) at the time of Giotto encounter. The related photo-chemical model calculations also indicate that Q(HN3)/Q(H2O) equals about 0.005, in agreement with recent determination from ground-based observations. The estimated value of Q(HCN) is lower than the relative abundance of Q(HCN)/Q(H2O) of about 0.001, as derived from radio observations of the 88.6 GHz emission of the J = 1 - 0 transition of HCN. The difference may be the result of time variations of the coma composition and dynamics, as well as other model-dependent effects.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/237733','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/237733"><span>High strain rate mechanical properties of <span class="hlt">IM</span>7/8551-7 graphite epoxy composite</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Powers, B.M.; Vinson, J.R.; Hall, I.W.</p> <p>1995-12-31</p> <p>Polymer matrix composites offer excellent mechanical properties such as high specific strength and stiffness which make them attractive for many naval, aerospace and automotive structural components. Although they are candidate materials for many applications where high strain rate loading is probable, little is known of the material responses to shock loading for most composite materials. Because mechanical properties vary significantly with strain rate, the use of static properties in the analysis and design of structures which undergo dynamic loadings can on one hand lead to a very conservative overweight design, or on the other hand can lead to designs which fail prematurely and unexpectedly. The use of dynamic material properties will ensure the design of composite structures which are weight efficient and structurally sound when they are subjected to dynamic loads. In this study, a Split Hopkinson Pressure Bar is used to obtain compressive mechanical properties of a unidirectional <span class="hlt">IM</span>7/8551-7 graphite epoxy composite. For each of the three principal directions, the yield stress, yield strain, ultimate stress, ultimate strain, modulus of elasticity, elastic strain energy function and the total strain energy to failure are presented for strain rates varying from 49 sec{sup {minus}1} to 1430 sec{sup {minus}1}. The data from 72 tests are statistically analyzed, represented by equations, and discussed in some detail.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25378316','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25378316"><span>IMGT®, the international <span class="hlt">Im</span>MunoGeneTics information system® 25 years on.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lefranc, Marie-Paule; Giudicelli, Véronique; Duroux, Patrice; Jabado-Michaloud, Joumana; Folch, Géraldine; Aouinti, Safa; Carillon, Emilie; Duvergey, Hugo; Houles, Amélie; Paysan-Lafosse, Typhaine; Hadi-Saljoqi, Saida; Sasorith, Souphatta; Lefranc, Gérard; Kossida, Sofia</p> <p>2015-01-01</p> <p>IMGT(®), the international <span class="hlt">Im</span>MunoGeneTics information system(®)(http://www.imgt.org) is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT(®) marked the advent of immunoinformatics, which emerged at the interface between immunogenetics and bioinformatics. IMGT(®) is specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH) and proteins of the IgSF and MhSF superfamilies. IMGT(®) is built on the IMGT-ONTOLOGY axioms and concepts, which bridged the gap between genes, sequences and 3D structures. The concepts include the IMGT(®) standardized keywords (identification), IMGT(®) standardized labels (description), IMGT(®) standardized nomenclature (classification), IMGT unique numbering and IMGT Colliers de Perles (numerotation). IMGT(®) comprises 7 databases, 17 online tools and 15,000 pages of web resources, and provides a high-quality and integrated system for analysis of the genomic and expressed IG and TR repertoire of the adaptive immune responses, including NGS high-throughput data. Tools and databases are used in basic, veterinary and medical research, in clinical applications (mutation analysis in leukemia and lymphoma) and in antibody engineering and humanization. The IMGT/mAb-DB interface was developed for therapeutic antibodies and fusion proteins for immunological applications (FPIA). IMGT(®) is freely available at http://www.imgt.org.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011AAS...21733915S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011AAS...21733915S"><span>Radial Distribution of Molecules and Ions in the Protoplanetary Disk Around <span class="hlt">IM</span> Lup</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Svoboda, Brian E.; Oberg, K. I.</p> <p>2011-01-01</p> <p>We present spatially and spectroscopically resolved Submillimeter Array (SMA) observations of 12CO J=2-1, 13CO J=2-1, DCO+ J=3-2, N2H+ J=3-2, and H2CO J=4(14)-3(13) line emission from the <span class="hlt">IM</span> Lup protoplanetary disk. We use Monte Carlo radiative transfer calculations to compare the SMA visibilities with tapered disk models, and use the results to constrain the outer radii of the emission regions. N2H+ and H2CO are proposed to trace dust grains at temperatures below 20 K, and DCO+ is proposed to trace gas temperatures below 40 K. The inferred outer radii for N2H+ and H2CO are both 600 AU, and 300-600 AU for DCO+. These values are consistent with thermally decoupled gas and dust in the outer disk. This work is supported in part by the NSF REU and DOD ASSURE programs under NSF grant no. 0754568 and by the Smithsonian Institution.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015ApJ...810..112O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015ApJ...810..112O"><span>Double DCO+ Rings Reveal CO Ice Desorption in the Outer Disk Around <span class="hlt">IM</span> Lup</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Öberg, Karin I.; Furuya, Kenji; Loomis, Ryan; Aikawa, Yuri; Andrews, Sean M.; Qi, Chunhua; van Dishoeck, Ewine F.; Wilner, David J.</p> <p>2015-09-01</p> <p>In a protoplanetary disk, a combination of thermal and non-thermal desorption processes regulate where volatiles are liberated from icy grain mantles into the gas phase. Non-thermal desorption should result in volatile-enriched gas in disk-regions where complete freeze-out is otherwise expected. We present Atacama Large Millimeter/Submillimeter Array observations of the disk around the young star <span class="hlt">IM</span> Lup in 1.4 mm continuum, C18O 2-1, H13CO+ 3-2 and DCO+ 3-2 emission at ˜0.″5 resolution. The images of these dust and gas tracers are clearly resolved. The DCO+ line exhibits a striking pair of concentric rings of emission that peak at radii of ˜0.″6 and 2″ (˜90 and 300 AU, respectively). Based on disk chemistry model comparison, the inner DCO+ ring is associated with the balance of CO freeze-out and thermal desorption due to a radial decrease in disk temperature. The outer DCO+ ring is explained by non-thermal desorption of CO ice in the low-column-density outer disk, repopulating the disk midplane with cold CO gas. The CO gas then reacts with abundant H2D+ to form the observed DCO+ outer ring. These observations demonstrate that spatially resolved DCO+ emission can be used to trace otherwise hidden cold gas reservoirs in the outmost disk regions, opening a new window onto their chemistry and kinematics.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11308369','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11308369"><span>Synthesis of structured lipids by transesterification of trilinolein catalyzed by Lipozyme <span class="hlt">IM</span>60.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sellappan, S; Akoh, C C</p> <p>2001-04-01</p> <p>Structured lipids (SL) containing caprylic, stearic, and linoleic acids were synthesized by enzymatic transesterification using Lipozyme <span class="hlt">IM</span>60. Pure trilinolein and free fatty acids were used as substrates. Incorporation of stearic acid was higher than that of caprylic acid in all parameters. Highest incorporations of both acids were achieved at 32 h, mole ratio of 1:4:4 (trilinolein/caprylic/stearic acids), water content of 1% (wt %), temperature of 55 degrees C, and 10% (wt %) enzyme load. The maximal incorporations of caprylic and stearic acids were 23.73 and 62.46 mol %, respectively. Reaction time, water content, and enzyme load had major influences on the reaction, whereas substrate mole ratio and temperature showed less influence. Lipozyme showed good stability over six reuses. Differential scanning calorimetric analysis of SL gave a melting profile with a very low melting peak of 0-3.3 degrees C and a solid fat content of 25.21% at 0 degrees C. The melting profile and solid fat content of SL were compared with those of fats extracted from commercially available solid and liquid margarine products. The data suggest that enzymatically produced SL could be used in liquid margarine products.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11555179','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11555179"><span>Disposition of oxytetracycline in pigs after <span class="hlt">i.m</span>. administration of two long-acting formulations.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>El Korchi, G; Prats, C; Arboix, M; Pérez, B</p> <p>2001-08-01</p> <p>Two commercially available long-acting oxytetracycline (OTC) formulations were administered by the intramuscular (<span class="hlt">i.m</span>.) route to six healthy pigs at the recommended dose of 30 mg/kg. After 2 h the mean maximum concentration (C(max)) reached values of 8.1 +/- 2.2 and 15.4 +/- 11.1 microg/mL, respectively. These concentrations remained higher than 0.5 microg/mL for more than 5 days after drug administration. The area under the concentration time curve (AUC09 days) of each formulation was 255 +/- 76.5 and 399.2 +/- 123 microg. h/mL, respectively, and the mean residence time (MRT) was around 3 days for both formulations. No significant differences were observed between the pharmacokinetic parameters of the two formulations, showing the bioequivalence of the two formulations studied according to the criteria established by the Food and Drug Administration (FDA) and the Committee for Veterinary Medicinal Products (CVMP).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23546148','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23546148"><span>Analytical formulation of directly modulated OOFDM signals transmitted over an <span class="hlt">IM</span>/DD dispersive link.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sánchez, C; Ortega, B; Wei, J L; Tang, J; Capmany, J</p> <p>2013-03-25</p> <p>We provide an analytical study on the propagation effects of a directly modulated OOFDM signal through a dispersive fiber and subsequent photo-detection. The analysis includes the effects of the laser operation point and the interplay between chromatic dispersion and laser chirp. The final expression allows to understand the physics behind the transmission of a multi-carrier signal in the presence of residual frequency modulation and the description of the induced intermodulation distortion gives us a detailed insight into the diferent intermodulation products which impair the recovered signal at the receiver-end side. Numerical comparisons between transmission simulations results and those provided by evaluating the expression obtained are carried out for different laser operation points. Results obtained by changing the fiber length, laser parameters and using single mode fiber with negative and positive dispersion are calculated in order to demonstrate the validity and versatility of the theory provided in this paper. Therefore, a novel analytical formulation is presented as a versatile tool for the description and study of <span class="hlt">IM</span>/DD OOFDM systems with variable design parameters.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006IJSEd..28.1041P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006IJSEd..28.1041P"><span>``Chemie <span class="hlt">im</span> Kontext'': A symbiotic implementation of a context-based teaching and learning approach</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Parchmann, Ilka; Gräsel, Cornelia; Baer, Anja; Nentwig, Peter; Demuth, Reinhard; Ralle, Bernd</p> <p>2006-07-01</p> <p>“Chemie <span class="hlt">im</span> Kontext” (ChiK) is a project that aims at the improvement of chemistry teaching at secondary school in Germany. Based on a framework that was derived from theories and empirical data on the teaching and learning of science, science education researchers and teachers work together on learning communities to transform this framework into teaching and learning practice. Funded by the German Federal Ministry of Education and the participating federal states, such learning communities have developed and tried units for almost all topics for upper and lower secondary education. The accompanying research studies show different effects on students’ motivation: The ChiK units point out the relevance of chemistry, but the student-oriented learning approach can also lead to a feeling of getting lost in the context. One reason might be seen in the result that teachers have put more emphasis on the realization of a good context than on the second important principle of ChiK—the development of basic concepts. However, data also showed that the learning communities have indeed inspired and supported the teachers to change their teaching towards a more context-based and student-oriented teaching. The continuing work will now especially focus on the improvement of facilitating the students with a better guideline, and on the development and assessment of different science competencies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28527668','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28527668"><span>Imaging mass spectrometry (<span class="hlt">IMS</span>) of cortical lipids from preclinical to severe stages of Alzheimer's disease.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gónzalez de San Román, E; Manuel, I; Giralt, M T; Ferrer, I; Rodríguez-Puertas, R</p> <p>2017-09-01</p> <p>Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting millions of patients worldwide. Previous studies have demonstrated alterations in the lipid composition of lipid extracts from plasma and brain samples of AD patients. However, there is no consensus regarding the qualitative and quantitative changes of lipids in brains from AD patients. In addition, the recent developments in imaging mass spectrometry methods are leading to a new stage in the in situ analysis of lipid species in brain tissue slices from human postmortem samples. The present study uses the matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-<span class="hlt">IMS</span>), permitting the direct anatomical analysis of lipids in postmortem brain sections from AD patients, which are compared with the intensity of the lipid signal in samples from matched subjects with no neurological diseases. The frontal cortex samples from AD patients were classified in three groups based on Braak's histochemical criteria, ranging from non-cognitively impaired patients to those severely affected. The main results indicate a depletion of different sulfatide lipid species from the earliest stages of the disease in both white and gray matter areas of the frontal cortex. Therefore, the decrease in sulfatides in cortical areas could be considered as a marker of the disease, but may also indicate neurochemical modifications related to the pathogenesis of the disease. This article is part of a Special Issue entitled: Membrane Lipid Therapy: Drugs Targeting Biomembranes edited by Pablo V. Escribá. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..1710304S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..1710304S"><span>Evaluating the CLimate and Air Quality <span class="hlt">Im</span>Pacts of Short-livEd Pollutants (ECLIPSE)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Stohl, Andreas</p> <p>2015-04-01</p> <p>The ECLIPSE (Evaluating the CLimate and Air Quality <span class="hlt">Im</span>Pacts of Short-livEd Pollutants) EU project studied the influence of short-lived climate forcers (SLCFs, e.g., aerosols, methane, ozone) on past, current and future climate and has finished in March 2015. ECLIPSE has created a consistent emission data set for short- and long-lived climate forcers for the recent past and future scenarios. This inventory also includes new source categories (e.g., gas flaring emissions) and is already in use by many groups worldwide. A small ensemble of models was used to quantify radiative forcing of SLCFs by region and sector. Existing and new metrics for quantifying climate impacts were studied and Global Temperature Change Potential on a 20-year time horizon (GTP20) was selected to rank potential emission mitigation measures. The 20 most effective measures with a non-negative impact on air quality were then used to define a mitigation scenario. For the first time, a small ensemble of coupled climate models performed transient model simulations of the control and the mitigation scenario, to quantify the impact of the SLCF mitigation measures on global and regional temperature and precipitation. This presentation will summarize the main findings of ECLIPSE and extract the policy-relevant recommendations from the project. Findings will also be discussed in the light of a detailed evaluation of the models against measurements in Europe, the Arctic and Asia.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17368898','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17368898"><span>Synthesis and evaluation of novel benzimidazole derivative [Bz-<span class="hlt">Im</span>] and its radio/biological studies.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tiwari, Anjani K; Mishra, Anil K; Bajpai, Aruna; Mishra, Pushpa; Singh, Sweta; Sinha, Deepa; Singh, V K</p> <p>2007-05-15</p> <p>Two different benzimidazole analogues act as multimodal agent, first one as novel non-peptidic CCK-B receptor antagonist and similarly as potent anti-fungal agent, designated as [Bz-<span class="hlt">Im</span>]. These compounds were synthesized and characterized by spectroscopic techniques such as FT-IR, NMR, EI-MS and also evaluated for specific radiopharmaceuticals. Preliminary radiolabeling results with (99m)Tc and biological evaluation studies showed promising results for further evaluation in vivo. The efficiency of labeling was more than 97% and complex was stable for about 12h at 30 degrees C in the presence of serum. Both ligands showed binding to most of the organs, known to express CCK receptors in biodistribution studies. Cholecystokinin (CCK(1) andCCK(2)) receptor binding affinities of these analogues are, IC(50), 0.942+/-0.107 for compound C and 0.665+/-0.211 for compound D in rat pancreatic acini. The anti-fungal activity has shown inhibitory activity against Aspergillus flavus and Aspergillus niger. These studies have provided a new template for further development of non-peptidic ligands for diagnostic and therapeutic purposes of diseases related with CCK receptors as well as anti-microbes.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002PhDT.......250M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002PhDT.......250M"><span>Mercaptursäure und Nukleosidaddukt <span class="hlt">im</span> Harn als Biomarker in 1-Hydroxymethylpyren-exponierten Ratten</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ma, Lan</p> <p>2002-01-01</p> <p>1-Methylpyren (MP) ist hepatokanzerogen in neugeborenen männlichen Mäusen. Durch Hydroxylierung an der benzylischen Stelle und anschließende Sulfonierung wird MP zu DNA-reaktivem 1-Sulfooxymethylpyren (SMP) aktiviert. In der Ratte führt die Exposition des benzylischen Alkohols, 1-Hydroxymethylpyren (HMP), zur DNA-Adduktbildung in verschiedenen Geweben. Eventuelle Konsequenz der Toxifizierung ist die Ausscheidung entsprechender Mercaptursäure und Nukleosidaddukt <span class="hlt">im</span> Harn, welche aufgrund ihrer Herkunft als Biomarker eignen könnten. In dieser Arbeit wird die Ausscheidung der Mercaptursäure und des N2-Desoxyguanosinadduktes in HMP-exponierten Ratten untersucht. Nach der Applikation von HMP bzw. MP wurden weniger als 1 % der Dosis als MPMA über Urin und Faeces ausgeschieden (0 - 48 h). Die Ausscheidung erfolgt hauptsächlich in den ersten 24 h nach der Applikation. MPdG konnte weder in Urin noch in Faeces der HMP-behandelten Tieren identifiziert werden. Nach direkter SMP-Applikation wurde MPdG nur in sehr geringe Menge (weniger als 0,9 ppm in 12 h) <span class="hlt">im</span> Urin gefunden. Aufgrund der geringen Menge eignet sich MPdG nicht als Biomarker. MPMA dagegen, lässt sich analytisch gut erfassen. Es sollte daher untersucht werden, ob MPMA die Toxifizierung des HMP wiederspiegelt. Die Voraussetzung dafür ist die Kenntnisse über das Metabolismusmuster von HMP. Es wurde daher umfassende Untersuchungen zum Metabolismus des HMP durchgeführt. Die Ergebnisse zeigten, dass mehr als 80 % der Metaboiten in ihrer oxidierten Form (PCS, deren Glucuronsäure-Konjugate sowie phenolische Sulfatester der PCS) ausgeschieden wurden. Demnach spielt die Oxidation des HMP zu PCS eine sehr wichtige Rolle bei der Detoxifizierung und Ausscheidung von HMP. Ferne konnte nachgewiesen werden, dass die Enzyme Alkohol- und Aldehyd-Dehydrogenase an der Oxidation von HMP beteiligt waren. Die Inhibitoren Disulfiram und Ethanol der o. g. Enzyme wurde daher zur Modulation der Detoxifizierung in vivo eingesetzt</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014NatSR...4E6187P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014NatSR...4E6187P"><span>The primary transcriptome of the marine diazotroph Trichodesmium erythraeum <span class="hlt">IMS</span>101</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Pfreundt, Ulrike; Kopf, Matthias; Belkin, Natalia; Berman-Frank, Ilana; Hess, Wolfgang R.</p> <p>2014-08-01</p> <p>Blooms of the dinitrogen-fixing marine cyanobacterium Trichodesmium considerably contribute to new nitrogen inputs into tropical oceans. Intriguingly, only 60% of the Trichodesmium erythraeum <span class="hlt">IMS</span>101 genome sequence codes for protein, compared with ~85% in other sequenced cyanobacterial genomes. The extensive non-coding genome fraction suggests space for an unusually high number of unidentified, potentially regulatory non-protein-coding RNAs (ncRNAs). To identify the transcribed fraction of the genome, here we present a genome-wide map of transcriptional start sites (TSS) at single nucleotide resolution, revealing the activity of 6,080 promoters. We demonstrate that T. erythraeum has the highest number of actively splicing group II introns and the highest percentage of TSS yielding ncRNAs of any bacterium examined to date. We identified a highly transcribed retroelement that serves as template repeat for the targeted mutation of at least 12 different genes by mutagenic homing. Our findings explain the non-coding portion of the T. erythraeum genome by the transcription of an unusually high number of non-coding transcripts in addition to the known high incidence of transposable elements. We conclude that riboregulation and RNA maturation-dependent processes constitute a major part of the Trichodesmium regulatory apparatus.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20010020091','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20010020091"><span>Automated Fiber Placement of PEEK/<span class="hlt">IM</span>7 Composites with Film Interleaf Layers</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Hulcher, A. Bruce; Banks, William I., III; Pipes, R. Byron; Tiwari, Surendra N.; Cano, Roberto J.; Johnston, Norman J.; Clinton, R. G., Jr. (Technical Monitor)</p> <p>2001-01-01</p> <p>The incorporation of thin discrete layers of resin between plies (interleafing) has been shown to improve fatigue and impact properties of structural composite materials. Furthermore, interleafing could be used to increase the barrier properties of composites used as structural materials for cryogenic propellant storage. In this work, robotic heated-head tape placement of PEEK/<span class="hlt">IM</span>7 composites containing a PEEK polymer film interleaf was investigated. These experiments were carried out at the NASA Langley Research Center automated fiber placement facility. Using the robotic equipment, an optimal fabrication process was developed for the composite without the interleaf. Preliminary interleaf processing trials indicated that a two-stage process was necessary; the film had to be tacked to the partially-placed laminate then fully melted in a separate operation. Screening experiments determined the relative influence of the various robotic process variables on the peel strength of the film-composite interface. Optimization studies were performed in which peel specimens were fabricated at various compaction loads and roller temperatures at each of three film melt processing rates. The resulting data were fitted with quadratic response surfaces. Additional specimens were fabricated at placement parameters predicted by the response surface models to yield high peel strength in an attempt to gage the accuracy of the predicted response and assess the repeatability of the process. The overall results indicate that quality PEEK/lM7 laminates having film interleaves can be successfully and repeatability fabricated by heated head automated fiber placement.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_21 --> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19960014851','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19960014851"><span>Physical aging effects on the compressive linear viscoelastic creep of <span class="hlt">IM</span>7/K3B composite</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Veazie, David R.; Gates, Thomas S.</p> <p>1995-01-01</p> <p>An experimental study was undertaken to establish the viscoelastic behavior of 1M7/K3B composite in compression at elevated temperature. Creep compliance, strain recovery and the effects of physical aging on the time dependent response was measured for uniaxial loading at several isothermal conditions below the glass transition temperature (T(g)). The <span class="hlt">IM</span>7/K3B composite is a graphite reinforced thermoplastic polyimide with a T(g) of approximately 240 C. In a composite, the two matrix dominated compliance terms associated with time dependent behavior occur in the transverse and shear directions. Linear viscoelasticity was used to characterize the creep/recovery behavior and superposition techniques were used to establish the physical aging related material constants. Creep strain was converted to compliance and measured as a function of test time and aging time. Results included creep compliance master curves, physical aging shift factors and shift rates. The description of the unique experimental techniques required for compressive testing is also given.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015MNRAS.449...25C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015MNRAS.449...25C"><span>The slow decline of the Galactic recurrent novae T Pyxidis, <span class="hlt">IM</span> Normae, and CI Aquilae</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Caleo, Andrea; Shore, Steven N.</p> <p>2015-05-01</p> <p>A distinguishing trait of the three known Galactic recurrent novae with the shortest orbital periods, T Pyx, <span class="hlt">IM</span> Nor, and CI Aql, is that their optical decline time-scales are significantly longer than those of the other recurrent systems. On the other hand, some estimates of the mass of the ejecta, the velocity of the ejecta, and the duration of the soft X-rays emission of these systems are of the order of those of the other recurrent systems and the fast classical novae. We put forth a tentative explanation of this phenomenon. We propose that in these systems part of the material transferred from the companion during the first few days of the eruption remains within the Roche lobe of the white dwarf, preventing the radiation from ionizing the ejecta of the system and increasing the optical decline time-scale. We explain why this phenomenon is more likely in systems with a high mass transfer rate and a short orbital period. Finally, we present a schematic model that shows that the material transferred from the companion is sufficient to absorb the radiation from the white dwarf in these systems, ultimately supporting this scenario as quantitatively realistic.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4674838','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4674838"><span>Indirectly Estimating International Net Migration Flows by Age and Gender: The Community Demographic Model International Migration (CDM-<span class="hlt">IM</span>) Dataset</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Nawrotzki, Raphael J.; Jiang, Leiwen</p> <p>2015-01-01</p> <p>Although data for the total number of international migrant flows is now available, no global dataset concerning demographic characteristics, such as the age and gender composition of migrant flows exists. This paper reports on the methods used to generate the CDM-<span class="hlt">IM</span> dataset of age and gender specific profiles of bilateral net (not gross) migrant flows. We employ raw data from the United Nations Global Migration Database and estimate net migrant flows by age and gender between two time points around the year 2000, accounting for various demographic processes (fertility, mortality). The dataset contains information on 3,713 net migrant flows. Validation analyses against existing data sets and the historical, geopolitical context demonstrate that the CDM-<span class="hlt">IM</span> dataset is of reasonably high quality. PMID:26692590</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24787881','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24787881"><span>A full-duplex lightwave transmission system with an innovative VCSEL-based PM-to-<span class="hlt">IM</span> converter.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lin, Chun-Yu; Lu, Hai-Han; Chang, Ching-Hung; Li, Chung-Yi; Jhang, Tai-Wei; Ruan, Sheng-Siang; Wu, Kuan-Hung</p> <p>2014-04-21</p> <p>A full-duplex lightwave transmission system employing innovative VCSEL-based PM-to-<span class="hlt">IM</span> converters to deliver intensity-modulated CATV/phase-modulated RoF/intensity-remodulated RoF signals over two 40-km SMFs links is proposed and demonstrated. To be the first one of employing VCSEL-based PM-to-<span class="hlt">IM</span> converters in full-duplex lightwave transmission systems, the downstream light is successfully intensity-remodulated with RoF signal for up-link transmission. Good performances of CNR/CSO/CTB are achieved for downstream CATV signal transmission, and low BER values are obtained for both downstream and upstream RoF signals transmissions. Our proposed systems present brilliant performances in delivering hybrid CATV and RoF signals. Such a full-duplex lightwave transmission system would be very attractive for fiber trunk applications to provide broadband integrated services.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA130041','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA130041"><span>Mechanisms of Corrosion Fatigue in High Strength <span class="hlt">I/M</span> (Ingot Metallurgy) and P/M (Powder Metallurgy) Aluminum Alloys.</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1983-02-01</p> <p>second year effort was devoted to the study of 7075 -T651 (I/Il) alloy, and X7091-T7E69 and X7091-T7E70 (P/M) alloys. The kinetics of fatigue crack...Qualification and Microstructural Characterization 6 3.2 Kinetics of Fatigue Crack Growth 7 3.2.1 7075 -T651 (<span class="hlt">I/M</span>) Aluminum Alloy 8 3.2.2 X7091-T7E69...and X7091-T7E70 (P/M) Aluminum Alloys 10 3.2.3 Comparison between <span class="hlt">I/M</span> and P/M Alloys and Discussions 12 3.3 Fractographic Analysis 14 3.3.1 7075 -T651</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25360539','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25360539"><span>Quantitative detection of benzene in toluene- and xylene-rich atmospheres using high-kinetic-energy ion mobility spectrometry (<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Langejuergen, Jens; Allers, Maria; Oermann, Jens; Kirk, Ansgar; Zimmermann, Stefan</p> <p>2014-12-02</p> <p>One major drawback of ion mobility spectrometry (<span class="hlt">IMS</span>) is the dependence of the response to a certain analyte on the concentration of water or the presence of other compounds in the sample gas. Especially for low proton affine analytes, e.g., benzene, which often exists in mixtures with other volatile organic compounds, such as toluene and xylene (BTX), a time-consuming preseparation is necessary. In this work, we investigate BTX mixtures using a compact <span class="hlt">IMS</span> operated at decreased pressure (20 mbar) and high kinetic ion energies (HiKE-<span class="hlt">IMS</span>). The reduced electric field in both the reaction tube and the drift tube can be independently increased up to 120 Td. Under these conditions, the water cluster distribution of reactant ions is shifted toward smaller clusters independent of the water content in the sample gas. Thus, benzene can be ionized via proton transfer from H3O(+) reactant ions. Also, a formation of benzene ions via charge transfer from NO(+) is possible. Furthermore, the time for interaction between ions and neutrals of different analytes is limited to such an extent that a simultaneous quantification of benzene, toluene, and xylene is possible from low ppbv up to several ppmv concentrations. The mobility resolution of the presented HiKE-<span class="hlt">IMS</span> varies from R = 65 at high field (90 Td) to R = 73 at lower field (40 Td) in the drift tube, which is sufficient to separate the analyzed compounds. The detection limit for benzene is 29 ppbv (2 s of averaging) with 3700 ppmv water, 12.4 ppmv toluene, and 9 ppmv xylene present in the sample gas. Furthermore, a less-moisture-dependent benzene measurement with a detection limit of 32 ppbv with ca. 21 000 ppmv (90% relative humidity (RH) at 20 °C) water present in the sample gas is possible evaluating the signal from benzene ions formed via charge transfer.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25059528','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25059528"><span>Bact<span class="hlt">Im</span>AS: a platform for processing and analysis of bacterial time-lapse microscopy movies.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mekterović, Igor; Mekterović, Darko; Maglica, Zeljka</p> <p>2014-07-25</p> <p>The software available to date for analyzing image sequences from time-lapse microscopy works only for certain bacteria and under limited conditions. These programs, mostly MATLAB-based, fail for microbes with irregular shape, indistinct cell division sites, or that grow in closely packed microcolonies. Unfortunately, many organisms of interest have these characteristics, and analyzing their image sequences has been limited to time consuming manual processing. Here we describe Bact<span class="hlt">Im</span>AS - a modular, multi-platform, open-source, Java-based software delivered both as a standalone program and as a plugin for Icy. The software is designed for extracting and visualizing quantitative data from bacterial time-lapse movies. Bact<span class="hlt">Im</span>AS uses a semi-automated approach where the user defines initial cells, identifies cell division events, and, if necessary, manually corrects cell segmentation with the help of user-friendly GUI and incorporated ImageJ application. The program segments and tracks cells using a newly-developed algorithm designed for movies with difficult-to-segment cells that exhibit small frame-to-frame differences. Measurements are extracted from images in a configurable, automated fashion and an SQLite database is used to store, retrieve, and exchange all acquired data. Finally, the Bact<span class="hlt">Im</span>AS can generate configurable lineage tree visualizations and export data as CSV files. We tested Bact<span class="hlt">Im</span>AS on time-lapse movies of Mycobacterium smegmatis and achieved at least 10-fold reduction of processing time compared to manual analysis. We illustrate the power of the visualization tool by showing heterogeneity of both icl expression and cell growth atop of a lineage tree. The presented software simplifies quantitative analysis of time-lapse movies overall and is currently the only available software for the analysis of mycobacteria-like cells. It will be of interest to the community of both end-users and developers of time-lapse microscopy software.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015GMDD....8.6267G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015GMDD....8.6267G"><span>Singular vector based targeted observations of chemical constituents: description and first application of the EURAD-<span class="hlt">IM</span>-SVA</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Goris, N.; Elbern, H.</p> <p>2015-08-01</p> <p>Measurements of the large dimensional chemical state of the atmosphere provide only sparse snapshots of the state of the system due to their typically insufficient temporal and spatial density. In order to optimize the measurement configurations despite those limitations, the present work describes the identification of sensitive states of the chemical system as optimal target areas for adaptive observations. For this purpose, the technique of singular vector analysis (SVA), which has been proved effective for targeted observations in numerical weather predication, is implemented into the chemical transport model EURAD-<span class="hlt">IM</span> (EURopean Air pollution and Dispersion - Inverse Model) yielding the EURAD-<span class="hlt">IM</span>-SVA. Besides initial values, emissions are investigated as critical simulation controlling targeting variables. For both variants, singular vectors are applied to determine the optimal placement for observations and moreover to quantify which chemical compounds have to be observed with preference. Based on measurements of the airship based ZEPTER-2 campaign, the EURAD-<span class="hlt">IM</span>-SVA has been evaluated by conducting a comprehensive set of model runs involving different initial states and simulation lengths. Since the considered cases are restricted in terms of considered chemical compounds and selected areas, they allow for a retracing of the results and a confirmation of their correctness. Our analysis shows that the optimal placement for observations of chemical species is not entirely determined by mere transport and mixing processes. Rather, a combination of initial chemical concentrations, chemical conversions, and meteorological processes determine the influence of chemical compounds and regions. We furthermore demonstrate that the optimal placement of observations of emission strengths is highly dependent on the location of emission sources and that the benefit of including emissions as target variables outperforms the value of initial value optimisation with growing</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19031872','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19031872"><span>A critical review of the effectiveness of <span class="hlt">I/M</span> programs for monitoring PM emissions from heavy duty vehicles.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Van Houtte, Jeroen; Niemeier, Deb</p> <p>2008-11-01</p> <p>Heavy-duty vehicles (HDV) are estimated to contribute up to 36% of particulate matter (PM) emissions in urban areas. In response, many agencies have established HDV inspection and maintenance (<span class="hlt">I/M</span>) programs designed to target and repair vehicles with excess emissions. In this review, we conduct an international comparison of legislative context and HDV <span class="hlt">I/M</span> program characteristics across Europe, North America, and Australia. The results of this analysis show that HDV-I/M programs vary greatly in terms of the ways in which testing is organized, for example, roadside versus periodic testing, whether the fleet is self-tested, and how nonfleet and age exemptions are handled. We also show how the <span class="hlt">I/M</span> test criteria have changed little in the last 15 years while regulations for new heavy-duty diesel engine emissions have become increasingly stringent. In the U.S., HDV engine PM emissions limits were reduced by a factor of 26 between 1997 and 2007. Most <span class="hlt">I/M</span> programs have continued to test according to EPA (and often with state legislative confirmation) guidance procedures having cut-points established in 1992. An analysis of data from Washington State show that only a minority of post-1997 vehicles actually exceeds the detection levels of the free-acceleration smoke-opacity test procedures, with the result that malfunctions of these vehicles may not actually be detected. From our review, it is clear that even with the potential adoption of new technologies and a more systematic and efficient framework for HDV-I/M, more research must be conducted in the efficacies of periodic versus roadside testing (and location selection), the use of evaluation methods like fail rates and opacity distributions, and finally, in development of better methods for identifying excess emissions with sensors and duty cycles.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20030001109&hterms=cemetery&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dcemetery','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20030001109&hterms=cemetery&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dcemetery"><span>Analytical/Operational Requirements for the In Situ Chemical Analysis of Cometary and Planetary Environments Using GC-<span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Takeuchi, Norishige; DeVincenizi, D. (Technical Monitor)</p> <p>2002-01-01</p> <p>Exobiology flight experiments require highly sensitive instrumentation for the in situ analysis of the volatile chemical species that occur in the atmospheres and surfaces of various bodies within the solar system. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The minimal resources available onboard for such missions mandate that the instruments provide maximum analytical capabilities with minimal requirements of volume, weight and consumables. The miniCIDEX instrument was developed for the chemical analysis of a cemetery environment. It combined a Gas Chromatograph (GC) with a helium based Ion Mobility Spectrometer (<span class="hlt">IMS</span>) to fulfill the analytical requirements of a cemetery exobiology mission: universal response; ppb sensitivity; low mass, volume and consumable MiniCIDEX is now a candidate for the chemical analysis instrument of a Titan Aero-rover Mission. The complexity of the analyses will be similar to the comet application with a heavier emphasis on organic molecules. Because the Titan Aero-Rover will be a balloon powered rover, much more attention is placed on the total mass of the instrument package. The GC will likely be a Micro-Electro-Mechanical-System (MEMS) design, smaller than the initial miniCIDEX GC by a factor of ten (with a similar reduction in consumable use). Similar miniaturization of the helium-based <span class="hlt">IMS</span> will be necessary while maintaining the analytical capabilities. The two mission applications, the analytical requirements, and the evolution of the <span class="hlt">IMS</span> design to accommodate these requirements will be presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21212239','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21212239"><span><span class="hlt">IM</span>-16: A new microporous germanosilicate with a novel framework topology containing d4r and mtw composite building units</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Lorgouilloux, Yannick; Dodin, Mathias; Paillaud, Jean-Louis Caullet, Philippe; Michelin, Laure; Josien, Ludovic; Ersen, Ovidiu; Bats, Nicolas</p> <p>2009-03-15</p> <p>The synthesis and the structure of <span class="hlt">IM</span>-16 a new germanosilicate with a novel zeolitic topology prepared hydrothermally with the ionic liquid 3-ethyl-1-methyl-3H-imidazol-1-ium as the organic structure-directing agent are reported. The structure of calcined and partially rehydrated <span class="hlt">IM</span>-16 of chemical formula |(H{sub 2}O){sub 0.16}|[Si{sub 3.47}Ge{sub 2.53}O{sub 12}] was solved from powder XRD data in space group Cmcm with a=15.0861(2) A, b=17.7719(3) A, c=19.9764(3) A, V=5355.84(12) A{sup 3} (Z=16). This new zeolite framework type contains 10-MRs channels and may be described from the d4r and mtw composite building units. - Graphical abstract: The synthesis and the structure of <span class="hlt">IM</span>-16 a new germanosilicate with a novel zeolitic topology prepared hydrothermally with the ionic liquid 3-ethyl-1-methyl-3H-imidazol-1-ium as the organic structure-directing agent are reported. This new zeolite framework type contains 10-MRs channels and may be described from the d4r and mtw composite building units.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24389704','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24389704"><span>Neurocognitive performance and symptom profiles of Spanish-speaking Hispanic athletes on the <span class="hlt">Im</span>PACT test.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ott, Summer; Schatz, Philip; Solomon, Gary; Ryan, Joseph J</p> <p>2014-03-01</p> <p>This study documented baseline neurocognitive performance of 23,815 athletes on the Immediate Post-Concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) test. Specifically, 9,733 Hispanic, Spanish-speaking athletes who completed the <span class="hlt">Im</span>PACT test in English and 2,087 Hispanic, Spanish-speaking athletes who completed the test in Spanish were compared with 11,955 English-speaking athletes who completed the test in English. Athletes were assigned to age groups (13-15, 16-18). Results revealed a significant effect of language group (p < .001; partial η(2) = 0.06) and age (p < .001; partial η(2) = 0.01) on test performance. Younger athletes performed more poorly than older athletes, and Spanish-speaking athletes completing the test in Spanish scored more poorly than Spanish-speaking and English-speaking athletes completing the test in English, on all Composite scores and Total Symptom scores. Spanish-speaking athletes completing the test in English also performed more poorly than English-speaking athletes completing the test in English on three Composite scores. These differences in performance and reported symptoms highlight the need for caution in interpreting <span class="hlt">Im</span>PACT test data for Hispanic Americans.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110016052','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110016052"><span>Study of Out-Time on the Processing and Properties of <span class="hlt">IM</span>7/977-3 Composites</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Miller, Sandi G.; Sutter, James K.; Scheiman, Daniel A.; Maryanski, Michael; Schlea, Michelle</p> <p>2010-01-01</p> <p>The capability to manufacture large structures leads to weight savings and reduced risk relative to joining smaller components. However, manufacture of increasingly large composite components is pushing the out-life limits of epoxy/ carbon fiber prepreg. <span class="hlt">IM</span>7/977-3 is an autoclave processable prepreg material, commonly used in aerospace structures. The out-life limit is reported as 30 days by the manufacturer. The purpose of this work was to evaluate the material processability and composite properties of 977-3 resin and <span class="hlt">IM</span>7/977-3 prepreg that had been aged at room temperature for up to 60 days. The neat resin was evaluated by differential scanning calorimetry, DSC, to characterize cure behavior of the aged material, as well as any change in activation energy. The rise in the modulus of the uncured prepreg was monitored throughout the 60 days by dynamic mechanical analysis, DMA. Composite panels made of the fresh and aged prepreg material were also characterized by DMA. The overall test results suggested that <span class="hlt">IM</span>7/977-3 was a robust material that offered quality laminates throughout this aging process when processed by autoclave.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/458659','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/458659"><span>PM-10 exhaust samples collected during <span class="hlt">IM</span>-240 dyanamometer tests of in-service vehicles in Nevada</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Sagebiel, J.C.; Zielinska, B.; Walsh, P.A.; Chow, J.C.; Cadle, S.H.; Mulawa, P.A.; Knapp, K.T.; Zweidinger, R.B.; Snow, R.</p> <p>1997-01-01</p> <p>Twenty-three vehicles that were recruited by remote sensing and roadside inspection and maintenance (<span class="hlt">I/M</span>) checks during the 1994 Clark and Washoe Remote Sensing Study (CAWRSS) were tested on the <span class="hlt">IM</span>240 cycle using a transportable dynamometer. Six of these vehicles emitted visible smoke. Total gas-phase hydrocarbon (HC), carbon monoxide (CO), and nitrogen oxides (NO{sub x}) exhaust concentrations were continuously measured in the diluted exhaust stream from the constant volume sampler (CVS) during <span class="hlt">IM</span>240 testing. Two isokinetic PM-10 samples were collected simultaneously using cyclones and filter holders connected to a dilution tube. Teflon filters were collected for total mass and then extracted for chloride, nitrate, and sulfate ions. Quartz filters were analyzed by the thermal/optical reflectance method for organic and elemental carbon. The quartz filters and backup vapor traps were then extracted and analyzed by GC/MS for 28 separate polynuclear aromatic hydrocarbons. Mass emission rates of PM-10 per vehicle ranged from 5.6 to over 1300 mg/mi, with most of the mass attributable to carbon. Except for one vehicle with high sulfate emissions, the ion emissions were relatively low. Total PAH emissions were in the range of 10-200 mg/mi. 10 refs., 8 figs., 5 tabs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20030001109&hterms=micro+gc&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dmicro%2Bgc','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20030001109&hterms=micro+gc&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dmicro%2Bgc"><span>Analytical/Operational Requirements for the In Situ Chemical Analysis of Cometary and Planetary Environments Using GC-<span class="hlt">IMS</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Takeuchi, Norishige; DeVincenizi, D. (Technical Monitor)</p> <p>2002-01-01</p> <p>Exobiology flight experiments require highly sensitive instrumentation for the in situ analysis of the volatile chemical species that occur in the atmospheres and surfaces of various bodies within the solar system. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The minimal resources available onboard for such missions mandate that the instruments provide maximum analytical capabilities with minimal requirements of volume, weight and consumables. The miniCIDEX instrument was developed for the chemical analysis of a cemetery environment. It combined a Gas Chromatograph (GC) with a helium based Ion Mobility Spectrometer (<span class="hlt">IMS</span>) to fulfill the analytical requirements of a cemetery exobiology mission: universal response; ppb sensitivity; low mass, volume and consumable MiniCIDEX is now a candidate for the chemical analysis instrument of a Titan Aero-rover Mission. The complexity of the analyses will be similar to the comet application with a heavier emphasis on organic molecules. Because the Titan Aero-Rover will be a balloon powered rover, much more attention is placed on the total mass of the instrument package. The GC will likely be a Micro-Electro-Mechanical-System (MEMS) design, smaller than the initial miniCIDEX GC by a factor of ten (with a similar reduction in consumable use). Similar miniaturization of the helium-based <span class="hlt">IMS</span> will be necessary while maintaining the analytical capabilities. The two mission applications, the analytical requirements, and the evolution of the <span class="hlt">IMS</span> design to accommodate these requirements will be presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4586386','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4586386"><span>Enhancing Biological Analyses with Three Dimensional Field Asymmetric Ion Mobility, Low Field Drift Tube Ion Mobility and Mass Spectrometry (μFAIMS/<span class="hlt">IMS</span>-MS) Separations</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Zhang, Xing; Ibrahim, Yehia M.; Chen, Tsung-Chi; Kyle, Jennifer E.; Norheim, Randolph V.; Monroe, Matthew E.; Smith, Richard D.; Baker, Erin S.</p> <p>2015-01-01</p> <p>Multidimensional high throughput separations are ideal for analyzing distinct ion characteristics simultaneously in one analysis. We report on the first evaluation of a platform coupling a high speed field asymmetric ion mobility spectrometry microchip (μFAIMS) with drift tube ion mobility and mass spectrometry (<span class="hlt">IMS</span>-MS). The μFAIMS/<span class="hlt">IMS</span>-MS platform was used to analyze biological samples and simultaneously acquire multidimensional FAIMS compensation fields, <span class="hlt">IMS</span> drift times, and accurate ion masses for the detected features. These separations thereby increased the overall measurement separation power, resulting in greater information content and more complete characterization of the complex samples. The separation conditions were optimized for sensitivity and resolving power by the selection of gas compositions and pressures in the FAIMS and <span class="hlt">IMS</span> separation stages. The resulting performance provided three dimensional separations, benefitting both broad complex mixture studies and targeted analyses by improving isomeric separations and allowing detection of species obscured by interfering peaks. PMID:26140287</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=314570&keyword=dog&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=314570&keyword=dog&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>Development of a human-specific B. thetaiotaomicron <span class="hlt">IMS</span>/ATP assay for measuring viable human contamination in surface waters in Baja California, Mexico</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Immunomagnetic separation/adenosine triphosphate (<span class="hlt">IMS</span>/ATP) assays utilize paramagnetic beads and target-specific antibodies to isolate target organisms. Following isolation, adenosine tri-phosphate (ATP) is extracted from the target population and quantified. An inversely-couple...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013pkk..book..243N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013pkk..book..243N"><span>Die Pugwash Conferences on Science and World Affairs Ein Beispiel für erfolgreiche „Track-II-Diplomacy“ der Naturwissenschaftler <span class="hlt">im</span> Kalten Krieg</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Neuneck, Götz</p> <p></p> <p>"Kein Zeitalter der Geschichte ist stärker von den Naturwissenschaften durchdrungen und abhängiger von ihnen als das 20. Jahrhundert" schreibt Eric Hobsbawn <span class="hlt">im</span> Kapitel "Zauberer und Lehrlinge: Die Naturwissenschaften" seines Buches "Zeitalter der Extreme".</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=314570&keyword=dog+OR+cat+AND+genetics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=91056668&CFTOKEN=87029021','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=314570&keyword=dog+OR+cat+AND+genetics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=91056668&CFTOKEN=87029021"><span>Development of a human-specific B. thetaiotaomicron <span class="hlt">IMS</span>/ATP assay for measuring viable human contamination in surface waters in Baja California, Mexico</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Immunomagnetic separation/adenosine triphosphate (<span class="hlt">IMS</span>/ATP) assays utilize paramagnetic beads and target-specific antibodies to isolate target organisms. Following isolation, adenosine tri-phosphate (ATP) is extracted from the target population and quantified. An inversely-couple...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1212243','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1212243"><span>Enhancing Biological Analyses with Three Dimensional Field Asymmetric Ion Mobility, Low Field Drift Time Ion Mobility and Mass Spectrometry (µFAIMS/<span class="hlt">IMS</span>-MS) Separations</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhang, Xing; Ibrahim, Yehia M.; Chen, Tsung-Chi; Kyle, Jennifer E.; Norheim, Randolph V.; Monroe, Matthew E.; Smith, Richard D.; Baker, Erin Shammel</p> <p>2015-06-30</p> <p>We report the first evaluation of a platform coupling a high speed field asymmetric ion mobility spectrometry microchip (µFAIMS) with drift tube ion mobility and mass spectrometry (<span class="hlt">IMS</span>-MS). The µFAIMS/<span class="hlt">IMS</span>-MS platform was used to analyze biological samples and simultaneously acquire multidimensional information of detected features from the measured FAIMS compensation fields and <span class="hlt">IMS</span> drift times, while also obtaining accurate ion masses. These separations thereby increase the overall separation power, resulting increased information content, and provide more complete characterization of more complex samples. The separation conditions were optimized for sensitivity and resolving power by the selection of gas compositions and pressures in the FAIMS and <span class="hlt">IMS</span> separation stages. The resulting performance provided three dimensional separations, benefitting both broad complex mixture studies and targeted analyses by e.g. improving isomeric separations and allowing detection of species obscured by “chemical noise” and other interfering peaks.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28300492','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28300492"><span>Recent <span class="hlt">im</span>/migration to Canada linked to unmet health needs among sex workers in Vancouver, Canada: Findings of a longitudinal study.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sou, Julie; Goldenberg, Shira M; Duff, Putu; Nguyen, Paul; Shoveller, Jean; Shannon, Kate</p> <p>2017-03-16</p> <p>Despite universal health care in Canada, sex workers (SWs) and <span class="hlt">im</span>/migrants experience suboptimal health care access. In this analysis, we examined the correlates of unmet health needs among SWs in Metro Vancouver over time. Data from a longitudinal cohort of women SWs (An Evaluation of Sex Workers Health Access [AESHA]) were used. Of 742 SWs, 25.5% reported unmet health needs at least once over the 4-year study period. In multivariable logistic regression using generalized estimating equations, recent <span class="hlt">im</span>/migration had the strongest impact on unmet health needs; long-term <span class="hlt">im</span>/migration, policing, and trauma were also important determinants. Legal and social supports to promote <span class="hlt">im</span>/migrant SWs' access to health care are recommended.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28123528','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28123528"><span>Effects of anti-CD44 monoclonal antibody <span class="hlt">IM</span>7 carried with chitosan polylactic acid-coated nano-particles on the treatment of ovarian cancer.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yang, Yizhuo; Zhao, Xinghui; Li, Xiuli; Yan, Zhifeng; Liu, Zhongyu; Li, Yali</p> <p>2017-01-01</p> <p>Failure in early diagnosis and ineffective treatment are the major causes of ovarian cancer mortality. Hyaluronan and its receptor, cluster of differentiation (CD)44, have been considered to be valid targets for treating cancer. The anti-CD44 monoclonal antibody <span class="hlt">IM</span>7 is effective in treating ovarian cancer; however, its toxicity should not be ignored. The present study has developed a new drug carrier system composed of chitosan nano-particles coated with polylactic acid (PLA) to improve the treatment efficacy and reduce toxicity. An ionic crosslinking method and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride/N-hydroxysuccinimide were used to prepare the <span class="hlt">IM</span>7 antibody, which was loaded with chitosan nano-particles. The surfaces of the nano-particles were coated with PLA to generate PLA-chitosan-<span class="hlt">IM</span>7. Subsequently, transmission electron microscopy (TEM) was used to observe the size and zeta potential of the nano-particles. In addition, a spectrophotometer was used to calculate the loading rate and release rate of the nano-particles in acidic and neutral environments. MTT assay was used to evaluate the anti-proliferative effect of PLA-chitosan-<span class="hlt">IM</span>7 on the human ovarian cancer cell line HO-8910PM. In addition, an in vivo imaging system was used to further investigate the effect of PLA-chitosan-<span class="hlt">IM</span>7 on the treatment of mice with ovarian cancer. A total of 35 days subsequent to PLA-chitosan-<span class="hlt">IM</span>7 treatment, all animals were sacrificed by CO2, and the tumors were removed and weighted. The PLA-chitosan-<span class="hlt">IM</span>7 nano-particles were successfully prepared, since TEM revealed that their size was 300-400 nm and their zeta potential was +25 mV. According to the spectrophotometry results, the loading rate was 52%, and PLA-chitosan-<span class="hlt">IM</span>7 exhibited good resistance to acids. MTT assay demonstrated that PLA-chitosan-<span class="hlt">IM</span>7 could suppress the proliferation of HO-8910PM cells in vitro. The in vivo imaging system revealed that PLA-chitosan-<span class="hlt">IM</span>7 was effective in controlling the development</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5245159','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5245159"><span>Effects of anti-CD44 monoclonal antibody <span class="hlt">IM</span>7 carried with chitosan polylactic acid-coated nano-particles on the treatment of ovarian cancer</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Yang, Yizhuo; Zhao, Xinghui; Li, Xiuli; Yan, Zhifeng; Liu, Zhongyu; Li, Yali</p> <p>2017-01-01</p> <p>Failure in early diagnosis and ineffective treatment are the major causes of ovarian cancer mortality. Hyaluronan and its receptor, cluster of differentiation (CD)44, have been considered to be valid targets for treating cancer. The anti-CD44 monoclonal antibody <span class="hlt">IM</span>7 is effective in treating ovarian cancer; however, its toxicity should not be ignored. The present study has developed a new drug carrier system composed of chitosan nano-particles coated with polylactic acid (PLA) to improve the treatment efficacy and reduce toxicity. An ionic crosslinking method and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride/N-hydroxysuccinimide were used to prepare the <span class="hlt">IM</span>7 antibody, which was loaded with chitosan nano-particles. The surfaces of the nano-particles were coated with PLA to generate PLA-chitosan-<span class="hlt">IM</span>7. Subsequently, transmission electron microscopy (TEM) was used to observe the size and zeta potential of the nano-particles. In addition, a spectrophotometer was used to calculate the loading rate and release rate of the nano-particles in acidic and neutral environments. MTT assay was used to evaluate the anti-proliferative effect of PLA-chitosan-<span class="hlt">IM</span>7 on the human ovarian cancer cell line HO-8910PM. In addition, an in vivo imaging system was used to further investigate the effect of PLA-chitosan-<span class="hlt">IM</span>7 on the treatment of mice with ovarian cancer. A total of 35 days subsequent to PLA-chitosan-<span class="hlt">IM</span>7 treatment, all animals were sacrificed by CO2, and the tumors were removed and weighted. The PLA-chitosan-<span class="hlt">IM</span>7 nano-particles were successfully prepared, since TEM revealed that their size was 300–400 nm and their zeta potential was +25 mV. According to the spectrophotometry results, the loading rate was 52%, and PLA-chitosan-<span class="hlt">IM</span>7 exhibited good resistance to acids. MTT assay demonstrated that PLA-chitosan-<span class="hlt">IM</span>7 could suppress the proliferation of HO-8910PM cells in vitro. The in vivo imaging system revealed that PLA-chitosan-<span class="hlt">IM</span>7 was effective in controlling the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..18.1862M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..18.1862M"><span>Using <span class="hlt">IMS</span> hydrophone data for detecting submarine volcanic activity: Insights from Monowai, 26°S Kermadec Arc</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Metz, Dirk; Watts, Anthony B.; Grevemeyer, Ingo; Rodgers, Mel; Paulatto, Michele</p> <p>2016-04-01</p> <p>Only little is known on active volcanism in the ocean. As eruptions are attenuated by seawater and fallout does not regularly reach the sea surface, eruption rates and mechanisms are poorly understood. Estimations on the number of active volcanoes across the modern seas range from hundreds to thousands, but only very few active sites are known. Monowai is a submarine volcanic centre in the northern Kermadec Arc, Southwest Pacific Ocean. During May 2011, it erupted over a period of five days, with explosive activity directly linked to the generation of seismoacoustic tertiary waves ('T-phases'), recorded at three broadband seismic stations in the region. We show, using windowed cross-correlation and time-difference-of-arrival techniques, that T-phases associated with this eruption are detected as far as Ascension Island, South Atlantic Ocean, where two bottom-moored hydrophone arrays are operated as part of the International Monitoring System (<span class="hlt">IMS</span>) of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO). We observe a high incidence of T-phase arrivals during the time of the eruption, with the angle of arrival stabilizing at the geodesic azimuth between the <span class="hlt">IMS</span> arrays and Monowai. T-phases from the volcanic centre must therefore have propagated through the Sound Fixing And Ranging (SOFAR) channel in the South Pacific and South Atlantic Oceans and over a total geodesic range of approximately 15,800 km, one of the longest source-receiver distances of any naturally occurring underwater signal ever observed. Our findings, which are consistent with observations at regional broadband stations and two dimensional, long-range, parabolic equation modelling, highlight the exceptional capabilities of the hydroacoustic waveform component of the <span class="hlt">IMS</span> for remotely detecting episodes of submarine volcanic activity. Using Monowai and the hydrophone arrays at Ascension Island as a natural laboratory, we investigate the long-term eruptive record of a submarine volcano from</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4946914','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4946914"><span>Organization into Higher Ordered Ring Structures Counteracts Membrane Binding of <span class="hlt">IM</span>30, a Protein Associated with Inner Membranes in Chloroplasts and Cyanobacteria*</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Heidrich, Jennifer; Wulf, Verena; Hennig, Raoul; Saur, Michael; Markl, Jürgen; Sönnichsen, Carsten; Schneider, Dirk</p> <p>2016-01-01</p> <p>The <span class="hlt">IM</span>30 (inner membrane-associated protein of 30 kDa), also known as the Vipp1 (vesicle-inducing protein in plastids 1), has a crucial role in thylakoid membrane biogenesis and maintenance. Recent results suggest that the protein binds peripherally to membranes containing negatively charged lipids. However, although <span class="hlt">IM</span>30 monomers interact and assemble into large oligomeric ring complexes with different numbers of monomers, it is still an open question whether ring formation is crucial for membrane interaction. Here we show that binding of <span class="hlt">IM</span>30 rings to negatively charged phosphatidylglycerol membrane surfaces results in a higher ordered membrane state, both in the head group and in the inner core region of the lipid bilayer. Furthermore, by using gold nanorods covered with phosphatidylglycerol layers and single particle spectroscopy, we show that not only <span class="hlt">IM</span>30 rings but also lower oligomeric <span class="hlt">IM</span>30 structures interact with membranes, although with higher affinity. Thus, ring formation is not crucial for, and even counteracts, membrane interaction of <span class="hlt">IM</span>30. PMID:27226585</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27226585','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27226585"><span>Organization into Higher Ordered Ring Structures Counteracts Membrane Binding of <span class="hlt">IM</span>30, a Protein Associated with Inner Membranes in Chloroplasts and Cyanobacteria.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Heidrich, Jennifer; Wulf, Verena; Hennig, Raoul; Saur, Michael; Markl, Jürgen; Sönnichsen, Carsten; Schneider, Dirk</p> <p>2016-07-15</p> <p>The <span class="hlt">IM</span>30 (inner membrane-associated protein of 30 kDa), also known as the Vipp1 (vesicle-inducing protein in plastids 1), has a crucial role in thylakoid membrane biogenesis and maintenance. Recent results suggest that the protein binds peripherally to membranes containing negatively charged lipids. However, although <span class="hlt">IM</span>30 monomers interact and assemble into large oligomeric ring complexes with different numbers of monomers, it is still an open question whether ring formation is crucial for membrane interaction. Here we show that binding of <span class="hlt">IM</span>30 rings to negatively charged phosphatidylglycerol membrane surfaces results in a higher ordered membrane state, both in the head group and in the inner core region of the lipid bilayer. Furthermore, by using gold nanorods covered with phosphatidylglycerol layers and single particle spectroscopy, we show that not only <span class="hlt">IM</span>30 rings but also lower oligomeric <span class="hlt">IM</span>30 structures interact with membranes, although with higher affinity. Thus, ring formation is not crucial for, and even counteracts, membrane interaction of <span class="hlt">IM</span>30. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26920773','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26920773"><span><span class="hlt">im</span>FASP: An integrated approach combining in-situ filter-aided sample pretreatment with microwave-assisted protein digestion for fast and efficient proteome sample preparation.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhao, Qun; Fang, Fei; Wu, Ci; Wu, Qi; Liang, Yu; Liang, Zhen; Zhang, Lihua; Zhang, Yukui</p> <p>2016-03-17</p> <p>An integrated sample preparation method, termed "<span class="hlt">im</span>FASP", which combined in-situ filter-aided sample pretreatment and microwave-assisted trypsin digestion, was developed for preparation of microgram and even nanogram amounts of complex protein samples with high efficiency in 1 h. For <span class="hlt">im</span>FASP method, proteins dissolved in 8 M urea were loaded onto a filter device with molecular weight cut off (MWCO) as 10 kDa, followed by in-situ protein preconcentration, denaturation, reduction, alkylation, and microwave-assisted tryptic digestion. Compared with traditional in-solution sample preparation method, <span class="hlt">im</span>FASP method generated more protein and peptide identifications (IDs) from preparation of 45 μg Escherichia coli protein sample due to the higher efficiency, and the sample preparation throughput was significantly improved by 14 times (1 h vs. 15 h). More importantly, when the starting amounts of E. coli cell lysate decreased to nanogram level (50-500 ng), the protein and peptide identified by <span class="hlt">im</span>FASP method were improved at least 30% and 44%, compared with traditional in-solution preparation method, suggesting dramatically higher peptide recovery of <span class="hlt">im</span>FASP method for trace amounts of complex proteome samples. All these results demonstrate that the <span class="hlt">im</span>FASP method developed here is of high potential for high efficient and high throughput preparation of trace amounts of complex proteome samples.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017SPIE10080E..08C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017SPIE10080E..08C"><span>SERS-based inverse molecular sentinel (<span class="hlt">iMS</span>) nanoprobes for multiplexed detection of microRNA cancer biomarkers in biological samples</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Crawford, Bridget M.; Wang, Hsin-Neng; Fales, Andrew M.; Bowie, Michelle L.; Seewaldt, Victoria L.; Vo-Dinh, Tuan</p> <p>2017-02-01</p> <p>The development of sensitive and selective biosensing techniques is of great interest for clinical diagnostics. Here, we describe the development and application of a surface enhanced Raman scattering (SERS) sensing technology, referred to as "inverse Molecular Sentinel (<span class="hlt">iMS</span>)" nanoprobes, for the detection of nucleic acid biomarkers in biological samples. This <span class="hlt">iMS</span> nanoprobe involves the use of plasmonic-active nanostars as the sensing platform for a homogenous assay for multiplexed detection of nucleic acid biomarkers, including DNA, RNA and microRNA (miRNA). The "OFF-to-ON" signal switch is based on a non-enzymatic strand-displacement process and the conformational change of stem-loop (hairpin) oligonucleotide probes upon target binding. Here, we demonstrate the development of <span class="hlt">iMS</span> nanoprobes for the detection of DNA sequences as well as a modified design of the nanoprobe for the detection of short (22-nt) microRNA sequences. The application of <span class="hlt">iMS</span> nanoprobes to detect miRNAs in real biological samples was performed with total small RNA extracted from breast cancer cell lines. The multiplex capability of the <span class="hlt">iMS</span> technique was demonstrated using a mixture of the two differently labeled nanoprobes to detect miR-21 and miR-34a miRNA biomarkers for breast cancer. The results of this study demonstrate the feasibility of applying the <span class="hlt">iMS</span> technique for multiplexed detection of nucleic acid biomarkers, including short miRNAs molecules.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApJ...832..110C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApJ...832..110C"><span>The Coupled Physical Structure of Gas and Dust in the <span class="hlt">IM</span> Lup Protoplanetary Disk</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cleeves, L. Ilsedore; Öberg, Karin I.; Wilner, David J.; Huang, Jane; Loomis, Ryan A.; Andrews, Sean M.; Czekala, Ian</p> <p>2016-12-01</p> <p>The spatial distribution of gas and solids in protoplanetary disks determines the composition and formation efficiency of planetary systems. A number of disks show starkly different distributions for the gas and small grains compared to millimeter-centimeter-sized dust. We present new Atacama Large Millimeter/Submillimeter Array observations of the dust continuum, CO, 13CO, and C18O in the <span class="hlt">IM</span> Lup protoplanetary disk, one of the first systems where this dust-gas dichotomy was clearly seen. The 12CO is detected out to a radius of 970 au, while the millimeter continuum emission is truncated at just 313 au. Based upon these data, we have built a comprehensive physical and chemical model for the disk structure, which takes into account the complex, coupled nature of the gas and dust and the interplay between the local and external environment. We constrain the distributions of gas and dust, the gas temperatures, the CO abundances, the CO optical depths, and the incident external radiation field. We find that the reduction/removal of dust from the outer disk exposes this region to higher stellar and external radiation and decreases the rate of freeze-out, allowing CO to remain in the gas out to large radial distances. We estimate a gas-phase CO abundance of 5% of the interstellar medium value and a low external radiation field (G 0 ≲ 4). The latter is consistent with that expected from the local stellar population. We additionally find tentative evidence for ring-like continuum substructure, suggestions of isotope-selective photodissociation, and a diffuse gas halo.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3909201','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3909201"><span>Energetic Frustrations in Protein Folding at Residue Resolution: A Homologous Simulation Study of <span class="hlt">Im</span>9 Proteins</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Sun, Yunxiang; Ming, Dengming</p> <p>2014-01-01</p> <p>Energetic frustration is becoming an important topic for understanding the mechanisms of protein folding, which is a long-standing big biological problem usually investigated by the free energy landscape theory. Despite the significant advances in probing the effects of folding frustrations on the overall features of protein folding pathways and folding intermediates, detailed characterizations of folding frustrations at an atomic or residue level are still lacking. In addition, how and to what extent folding frustrations interact with protein topology in determining folding mechanisms remains unclear. In this paper, we tried to understand energetic frustrations in the context of protein topology structures or native-contact networks by comparing the energetic frustrations of five homologous <span class="hlt">Im</span>9 alpha-helix proteins that share very similar topology structures but have a single hydrophilic-to-hydrophobic mutual mutation. The folding simulations were performed using a coarse-grained Gō-like model, while non-native hydrophobic interactions were introduced as energetic frustrations using a Lennard-Jones potential function. Energetic frustrations were then examined at residue level based on φ-value analyses of the transition state ensemble structures and mapped back to native-contact networks. Our calculations show that energetic frustrations have highly heterogeneous influences on the folding of the four helices of the examined structures depending on the local environment of the frustration centers. Also, the closer the introduced frustration is to the center of the native-contact network, the larger the changes in the protein folding. Our findings add a new dimension to the understanding of protein folding the topology determination in that energetic frustrations works closely with native-contact networks to affect the protein folding. PMID:24498176</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22573828','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22573828"><span>Pharmacokinetics of human chorionic gonadotropin after <span class="hlt">i.m</span>. administration in goats (Capra hircus).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Saleh, M; Shahin, M; Wuttke, W; Gauly, M; Holtz, W</p> <p>2012-07-01</p> <p>The present investigation addresses the pharmacokinetics of human chorionic gonadotropin (hCG), intramuscularly (<span class="hlt">i.m</span>.) administered to goats. Nine pluriparous does of the Boer goat breed, 2-6 years of age and weighing 45-60 kg, were administered 500 IU hCG (2 ml Chorulon) deep into the thigh musculature 18 h after superovulatory FSH treatment. Blood samples were drawn from the jugular vein at 2  h intervals for the first 24h, at 6 h intervals until 42 h, and at 12 h intervals until 114 h after administration. After centrifugation, plasma hCG concentrations were determined by electrochemiluminescence immunoassay. Pharmacokinetical parameters were as follows: lag time, 0.4 (s.e.m. 0.1) h; absorption rate constant, 0.34 (s.e.m. 0.002) h; absorption half-life, 2.7 (s.e.m. 0.5) h; elimination rate constant, 0.02 (s.e.m. 0.002) h; biological half-life, 39.4 (s.e.m. 5.1) h; and apparent volume of distribution, 16.9 (s.e.m. 4.3) l. The plasma hCG profile was characterized by an absorption phase of 11.6 (s.e.m. 1.8) h and an elimination phase of 70.0 (s.e.m. 9.8) h, with considerable individual variation in bioavailability and pharmacokinetical parameters. Biological half-life was negatively correlated (P<0.05) with peak concentration (r=-0.76), absorption rate constant (r=-0.78), and elimination rate constant (r=-0.87). The results indicate that after rapid absorption, hCG remains in the circulation for an extended period. This has to be taken into account when assessing the stimulatory response to hCG treatment on an ovarian level.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22525457','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22525457"><span>DOUBLE DCO{sup +} RINGS REVEAL CO ICE DESORPTION IN THE OUTER DISK AROUND <span class="hlt">IM</span> LUP</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Öberg, Karin I.; Loomis, Ryan; Andrews, Sean M.; Qi, Chunhua; Wilner, David J.; Furuya, Kenji; Dishoeck, Ewine F. van; Aikawa, Yuri</p> <p>2015-09-10</p> <p>In a protoplanetary disk, a combination of thermal and non-thermal desorption processes regulate where volatiles are liberated from icy grain mantles into the gas phase. Non-thermal desorption should result in volatile-enriched gas in disk-regions where complete freeze-out is otherwise expected. We present Atacama Large Millimeter/Submillimeter Array observations of the disk around the young star <span class="hlt">IM</span> Lup in 1.4 mm continuum, C{sup 18}O 2–1, H{sup 13}CO{sup +} 3–2 and DCO{sup +} 3–2 emission at ∼0.″5 resolution. The images of these dust and gas tracers are clearly resolved. The DCO{sup +} line exhibits a striking pair of concentric rings of emission that peak at radii of ∼0.″6 and 2″ (∼90 and 300 AU, respectively). Based on disk chemistry model comparison, the inner DCO{sup +} ring is associated with the balance of CO freeze-out and thermal desorption due to a radial decrease in disk temperature. The outer DCO{sup +} ring is explained by non-thermal desorption of CO ice in the low-column-density outer disk, repopulating the disk midplane with cold CO gas. The CO gas then reacts with abundant H{sub 2}D{sup +} to form the observed DCO{sup +} outer ring. These observations demonstrate that spatially resolved DCO{sup +} emission can be used to trace otherwise hidden cold gas reservoirs in the outmost disk regions, opening a new window onto their chemistry and kinematics.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010AdRS....8..151R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010AdRS....8..151R"><span>Ansätze zur Ordnungsreduktion von nichtlinearen Oszillatormodellen zur Anwendung <span class="hlt">im</span> Schaltungsentwurf</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Reit, M.; Bremer, J.-K.; Mathis, W.; Stoop, R.</p> <p>2010-10-01</p> <p><span class="hlt">Im</span> Rahmen dieser Arbeit wird ein Konzept zur Ordnungsreduktion von höherdimensionalen nichtlinearen Oszillatormodellen vorgestellt. Hierbei werden zwei wesentliche Ziele verfolgt. Zum einen wird eine höherdimensionale Modellierung der Oszillatorschaltung verwendet. Hierdurch lassen sich die Einflüsse parasitärer Effekte sowie struktureller Erweiterungen auf das dynamische Verhalten des Systems berücksichtigen. Zum anderen wird durch eine anschließende Ordnungsreduktion über die Methode der Zentrumsmannigfaltigkeit eine zweidimensionale Systembeschreibung erzeugt, deren wesentliche Dynamik derjenigen des höherdimensionalen Systems entspricht. Durch diese, in der Ordnung reduzierte, nichtlineare und parameterabhängige Systembeschreibung wird die Anwendbarkeit nichtlinearer Analysemethoden ermöglicht bzw. vereinfacht. Mit der Anwendung der Andronov-Hopf-Bifurkationsanalyse auf das reduzierte System lässt sich eine Stabilitätsuntersuchung durchführen sowie die Amplitude und Frequenz aller Zustandsgrößen approximieren. Das vorgestellte Konzept wird anhand des Beispielsystems eines LC-Tank-VCOs durchgeführt. In this paper, an order reduction technique for higher-dimensional nonlinear oscillator models, based on a center manifold approach, is presented. By modeling the oscillator circuit in the higher-dimensional state space, influences of parasitic elements and of structural extensions of the oscillator architecture on the dynamical system behavior can be examined. Using the proposed order reduction technique, a generalized second order model will be derived, which includes selected design parameters of the higher order model. By using an Andronov-Hopf bifurcation analysis, the reduced system can be studied with respect to stability as well as the amplitude and frequency of the individual state variables. The concept is applied to the design of LC-tank VCOs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20040085965','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20040085965"><span>Thermal Effects on the Compressive Behavior of <span class="hlt">IM</span>7/PET15 Laminates</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Walker, Sandra Polesky</p> <p>2003-01-01</p> <p>The effect of changing operating temperature on the compressive response of <span class="hlt">IM</span>7/PETI5 composite laminates is investigated within this paper. The three temperatures evaluated for this study were 129 C, 21 C, and 177 C, a spectrum from cryogenic to an elevated operating temperature. Laminate compressive strength property testing was conducted using the Wyoming Combined Load Compression fixture to generate strength data at the three operating temperatures of interest for several lay-ups. A three-dimensional finite element analysis model of a [90/0]8s composite laminate subject to compressive loading is developed. The model is used to study the key attributes of the laminate that significantly influence the state of stress in the laminate. Both the resin rich layer located between lamina and the thermal residual stresses present in the laminate due to curing are included in the analysis model. For the laminate modeled, the effect of modeling temperature dependent material properties was determined to be insignificant for the operating temperatures studied. Simply using the material properties measured at the operating temperature of interest was sufficient for predicting stresses accurately in a linear analysis for the current problem. The three-dimensional analysis results revealed that the application of an applied compressive axial load in the 0-degree direction decreased the interlaminar stresses present in the laminate initially due to curing. Therefore, failure was concluded not be attributable to the interlaminar stresses in the composite laminate being studied when a compressive load is applied. The magnitude of the measured laminate compressive strength change with a change in temperature is concluded to be dominated by the change in the lamina compressive axial strength with a change in temperature.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3909717','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3909717"><span>ASPECTS score to select patients for endovascular treatment: the <span class="hlt">IMS</span>-III trial</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Hill, MD; Demchuk, AM; Goyal, M; Jovin, TG; Foster, LD; Tomsick, TA; von Kummer, R; Yeatts, SD; Palesch, YY; Broderick, JP</p> <p>2014-01-01</p> <p>Background and Purpose The <span class="hlt">IMS</span>-III trial randomized acute ischemic stroke patients to IV tPA plus endovascular therapy versus IV tPA therapy alone within 3 hours from symptom onset. A pre-defined secondary hypothesis was that subjects with significant early ischemic change on the baseline scan would not respond to endovascular therapy. Methods The primary outcome was 90-day mRS 0–2. The baseline and follow-up CT scan images were reviewed centrally, blinded to any clinical information. We assessed whether the baseline ASPECTS score predicted outcome, and interacted with study treatment. We analyzed subgroups defined by time from onset to IV tPA initiation and baseline occlusion status at a pre-specified alpha = 0.01. Results Baseline demographic and clinical characteristics of 656 randomized patients were similar between subjects with a baseline ASPECTS score 8–10 (58% of the study sample) vs 0–7. Subjects with ASPECTS 8–10 were almost twice as likely [RR 1.8 CI99 1.4–2.4] to achieve a favorable outcome. There was insufficient evidence of a treatment-by-ASPECTS interaction. In those treated with onset to IV tPA under 120 minutes, in CTA-proven ICA or MCA occlusion, and in both, results were similar. The probability of achieving recanalization (AOL 2–3) of the primary arterial occlusive lesion [RR 1.3 CI99 1.0–1.8] or achieving TICI 2b/3 reperfusion [RR 2.0 CI99 1.2–3.2] was higher among subjects with higher ASPECTS scores. Conclusions ASPECTS is a strong predictor of outcome and a predictor of reperfusion. ASPECTS did not identify a sub-population of subjects that particularly benefitted from endovascular therapy immediately after routine IV tPA. PMID:24335227</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28335090','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28335090"><span>In ovo vaccination using Eimeria profilin and Clostridium perfringens NetB proteins in Montanide <span class="hlt">IMS</span> adjuvant increases protective immunity against experimentally-induced necrotic enteritis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lillehoj, Hyun Soon; Jang, Seung Ik; Panebra, Alfredo; Lillehoj, Erik Peter; Dupuis, Laurent; Ben Arous, Juliette; Lee, Seung Kyoo; Oh, Sung Taek</p> <p>2017-10-01</p> <p>The effects of vaccinating 18-day-old chicken embryos with the combination of recombinant Eimeria profilin plus Clostridium perfringens (C. perfringens) NetB proteins mixed in the Montanide <span class="hlt">IMS</span> adjuvant on the chicken immune response to necrotic enteritis (NE) were investigated using an Eimeria maxima (E. maxima)/C. perfringens co-infection NE disease model that we previously developed. Eighteen-day-old broiler embryos were injected with 100 μL of phosphate-buffered saline, profilin, profilin plus necrotic enteritis B-like (NetB), profilin plus NetB/Montanide adjuvant (<span class="hlt">IMS</span> 106), and profilin plus Net-B/Montanide adjuvant (<span class="hlt">IMS</span> 101). After post-hatch birds were challenged with our NE experimental disease model, body weights, intestinal lesions, serum antibody levels to NetB, and proinflammatory cytokine and chemokine mRNA levels in intestinal intraepithelial lymphocytes were measured. Chickens in ovo vaccinated with recombinant profilin plus NetB proteins/<span class="hlt">IMS</span>106 and recombinant profilin plus NetB proteins/<span class="hlt">IMS</span>101 showed significantly increased body weight gains and reduced gut damages compared with the profilin-only group, respectively. Greater antibody response to NetB toxin were observed in the profilin plus NetB/<span class="hlt">IMS</span> 106, and profilin plus NetB/<span class="hlt">IMS</span> 101 groups compared with the other three vaccine/adjuvant groups. Finally, diminished levels of transcripts encoding for proinflammatory cytokines such as lipopolysaccharide-induced tumor necrosis factor-α factor, tumor necrosis factor superfamily 15, and interleukin-8 were observed in the intestinal lymphocytes of chickens in ovo injected with profilin plus NetB toxin in combination with <span class="hlt">IMS</span> 106, and profilin plus NetB toxin in combination with <span class="hlt">IMS</span> 101 compared with profilin protein alone bird. These results suggest that the Montanide <span class="hlt">IMS</span> adjuvants potentiate host immunity to experimentally-induced avian NE when administered in ovo in conjunction with the profilin and NetB proteins, and may reduce disease pathology by</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21700391','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21700391"><span>Montanide <span class="hlt">IMS</span> 1313 N VG PR nanoparticle adjuvant enhances antigen-specific immune responses to profilin following mucosal vaccination against Eimeria acervulina.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jang, Seung I; Lillehoj, Hyun S; Lee, Sung Hyen; Lee, Kyung Woo; Lillehoj, Erik P; Bertrand, François; Dupuis, Laurent; Deville, Sébastien</p> <p>2011-12-15</p> <p>This study investigated protection against Eimeria acervulina (E. acervulina) following vaccination of chickens with an Eimeria recombinant profilin in conjunction with different adjuvants, or by changing the route of administration of the adjuvants. Day-old broilers were immunized twice with profilin emulsified in Montanide <span class="hlt">IMS</span> 1313 N VG PR adjuvant (oral, nasal, or ocular routes), Montanide ISA 71 VG adjuvant (subcutaneous route), or Freund's adjuvant (subcutaneous route) and orally challenged with virulent E. acervulina parasites. Birds orally immunized with profilin plus <span class="hlt">IMS</span> 1313 N VG PR, or subcutaneously immunized with profilin plus ISA 71 VG, had increased body weight gains compared with animals nasally or ocularly immunized with profilin plus <span class="hlt">IMS</span> 1313 N VG PR, or subcutaneously immunized with profilin plus Freund's adjuvant. All adjuvant formulations, except for <span class="hlt">IMS</span> 1313 N VG PR given by the nasal or ocular routes, decreased fecal parasite excretion and/or reduced intestinal lesions, compared with non-vaccinated and infected controls. Compared with animals vaccinated with profilin plus Freund's adjuvant, chickens immunized with profilin plus <span class="hlt">IMS</span> 1313 N VG PR or ISA 71 VG showed higher post-infection intestinal levels of profilin-reactive IgY and secretary IgA antibodies. Finally, immunization with profilin in combination with ISA 71 VG was consistently better than profilin plus <span class="hlt">IMS</span> 1313 N VG PR or Freund's adjuvant for increasing the percentages of CD4(+), CD8(+), BU1(+), TCR1(+), and TCR2(+) intestinal lymphocytes. These results indicate that experimental immunization of chickens with the recombinant profilin subunit vaccine in conjunction with <span class="hlt">IMS</span> 1313 or ISA 71 VG adjuvants increases protective mucosal immunity against E. acervulina infection. Published by Elsevier B.V.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.1721H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.1721H"><span>Re-establishment of the <span class="hlt">IMS</span> Hydroacoustic Station HA03, Robinson Crusoe Island, Chile</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Haralabus, Georgios; Stanley, Jerry; Zampolli, Mario; Pautet, Lucie</p> <p>2015-04-01</p> <p>Water column hydrophone stations of the Comprehensive Nuclear-Test-Ban Treaty Organisation (CTBTO) International Monitoring System (<span class="hlt">IMS</span>) comprise typically two triplets of moored hydrophones deployed on both sides of an island. Triplet distances vary approximately between 50 - 200 km from the island, with each triplet connected to the receiving shore equipment by fibre-optic submarine data cables. Once deployed, the systems relay underwater acoustic waveforms in the band 1 - 100 Hz in real time to Vienna via a shore based satellite link. The design life of hydroacoustic (HA) stations is at least 20 years, without need for any maintenance of the underwater system (UWS). The re-establishment of hydrophone station HA03 at Robinson Crusoe Island (670 km West of the Chilean mainland) is presented here. The station was destroyed in February 2010 by a Tsunami induced by an 8.8 magnitude earthquake. After a major engineering and logistical undertaking HA03 is now back in operation since April 2014. The main phases of the project are presented: (i) the installation of a shore facility for the reception of the hydrophone data from the UWS, which also relays the data back to the CTBTO International Data Center (IDC) in Vienna via a real-time satellite connection, (ii) the manufacturing and testing of the system to meet the stringent requirements of the Nuclear-Test-Ban Treaty, and (iii) the installation of the UWS with a state-of-the-art cable ship. Examples of data acquired by HA03 are also presented. These include hydroacoustic signals from the 1 April 2014 magnitude 8.2 earthquake in Northern Chile, bursting underwater bubbles from a submarine volcano near the Mariana Islands (15,000 Km away from the station), and vocalizations from the numerous marine mammals which transit in the vicinity of HA03. The use of CTBTO data for scientific purposes is possible via the virtual Data Exploitation Centre (vDEC), which is a platform that enables registered researchers to access</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.6684J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.6684J"><span>Could the <span class="hlt">IMS</span> Infrasound Stations Support a Global Network of Small Aperture Seismic Arrays?</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>J, Gibbons, Steven; Kværna, Tormod; Mykkeltveit, Svein</p> <p>2015-04-01</p> <p>The infrasound stations of the International Monitoring System are arrays consisting of up to 15 sites and with apertures of up to 3 km. The arrays are distributed remarkably uniformly over the globe and provide excellent coverage of South America, Africa, and Antarctica. This is to say that there are many infrasound arrays in regions many thousands of kilometers from the closest seismic array. Several infrasound arrays are in the immediate vicinity of existing 3-component seismic stations and these provide us with examples of how typical seismic signals look at these locations. We can make idealized estimates of the predicted performance of seismic arrays, consisting of seismometers at each site of the infrasound arrays, by duplicating the signals from the 3-C stations at all sites of the array. However, the true performance of seismic arrays at these sites will depend both upon Signal-to-Noise Ratios of seismic signals and the coherence of both signal and noise between sensors. These properties can only be determined experimentally. Recording seismic data of sufficient quality at many of these arrays may require borehole deployments since the microbarometers in the infrasound arrays are often situated in vaults placed in soft sediments. The geometries of all the current <span class="hlt">IMS</span> infrasound arrays are examined and compared and we demonstrate that, from a purely geometrical perspective, essentially all the array configurations would provide seismic arrays with acceptable slowness resolution for both regional and teleseismic phase arrivals. Seismic arrays co-located with the infrasound arrays in many regions would likely enhance significantly the seismic monitoring capability in parts of the world where only 3-component stations are currently available. Co-locating seismic and infrasound sensors would facilitate the development of seismic arrays that share the infrastructure of the infrasound arrays, reducing the development and operational costs. Hosting countries might</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016MNRAS.456.3972S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016MNRAS.456.3972S"><span>Stable and unstable accretion in the classical T Tauri stars <span class="hlt">IM</span> Lup and RU Lup as observed by MOST</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Siwak, Michal; Ogloza, Waldemar; Rucinski, Slavek M.; Moffat, Anthony F. J.; Matthews, Jaymie M.; Cameron, Chris; Guenther, David B.; Kuschnig, Rainer; Rowe, Jason F.; Sasselov, Dimitar; Weiss, Werner W.</p> <p>2016-03-01</p> <p>Results of the time variability monitoring of the two classical T Tauri stars, RU Lup and <span class="hlt">IM</span> Lup, are presented. Three photometric data sets were utilized: (1) simultaneous (same field) MOST satellite observations over four weeks in each of the years 2012 and 2013, (2) multicolour observations at the South African Astronomical Observatory in April-May of 2013, (3) archival V-filter All Sky Automated Survey (ASAS) data for nine seasons, 2001-2009. They were augmented by an analysis of high-resolution, public-domain VLT-UT2 Ultraviolet Visual Echelle Spectrograph spectra from the years 2000 to 2012. From the MOST observations, we infer that irregular light variations of RU Lup are caused by stochastic variability of hotspots induced by unstable accretion. In contrast, the MOST light curves of <span class="hlt">IM</span> Lup are fairly regular and modulated with a period of about 7.19-7.58 d, which is in accord with ASAS observations showing a well-defined 7.247 ± 0.026 d periodicity. We propose that this is the rotational period of <span class="hlt">IM</span> Lup and is due to the changing visibility of two antipodal hotspots created near the stellar magnetic poles during the stable process of accretion. Re-analysis of RU Lup high-resolution spectra with the broadening function approach reveals signs of a large polar coldspot, which is fairly stable over 13 years. As the star rotates, the spot-induced depression of intensity in the broadening function profiles changes cyclically with period 3.710 58 d, which was previously found by the spectral cross-correlation method.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4128892','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4128892"><span>Evaluation of Interval Times from Onset to Reperfusion in Patients Undergoing Endovascular Therapy in the <span class="hlt">IMS</span> III Trial</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Goyal, Mayank; Almekhlafi, Mohammed A; Fan, Liqiong; Menon, Bijoy K; Demchuk, Andrew M; Yeatts, Sharon D; Hill, Michael D; Tomsick, Thomas; Khatri, Pooja; Zaidat, Osama O; Jauch, Edward C; Eesa, Muneer; Jovin, Tudor G; Broderick, Joseph P</p> <p>2014-01-01</p> <p>Background Meaningful delays occurred in the <span class="hlt">IMS</span> III trial. Analysis of the workflow will identify factors contributing to the in-hospital delays. Methods and Results In the endovascular arm of the <span class="hlt">IMS</span> III trial, these time intervals were calculated: stroke onset to ED arrival; ED to CT; CT to IV tPA start; IV tPA start to randomization; randomization to groin puncture; groin puncture to thrombus identification; thrombus identification to start of endovascular therapy; start of endovascular therapy to reperfusion. The effects of enrollment time, CTA use, inter-hospital transfers, and intubation on workflow were evaluated. Delays notably occurred in the time intervals from IV tPA initiation to groin puncture (median 84 minutes) and start of endovascular therapy to reperfusion (median 85 minutes). The CT to groin puncture time was significantly shorter during working hours than after. Times from ED to reperfusion and groin puncture to reperfusion decreased over the trial period. Patients with CTA had shorter ED to reperfusion and onset to reperfusion times. Transfer of patients resulted in a longer onset to reperfusion time compared to those treated in the same center. Age, sex, NIHSS, and intubation did not impact delays. Conclusions Important delays were identified prior to reperfusion in the <span class="hlt">IMS</span> III trial. Delays decreased as the trial progressed. Use of CTA and endovascular treatment in the same center were associated with time savings. These data may help in optimizing workflow in current and future endovascular trials. Clinical Trial Registration Information http://clinicaltrials.gov. Identifier: NCT00359424. PMID:24815501</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA275058','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA275058"><span>Initial Wave-Type Identification with Neural Networks and its Contribution to Automated Processing in <span class="hlt">IMS</span> Version 3.0</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1993-12-10</p> <p>0Z *~-- - - - a-I~~~ EnI*!- CS~t~ N ____N _ ___ CU 0 CSCC 00 0690co N N N NCD .7 L 0 <span class="hlt">IM</span>’ Ivo zo c so 0 0o 9L0 -d i 0 C- 0 In01 ______ 0 0__ _ ItI 0 0 c...Kuzmin, Extensions of the northern Europe regional array network - New small-aperture arrays in Apatity, Russia, and on the Arctic island of Spitsbergen...TASC, Inc. ATTN: Dr. R. Comer 55 Walkers Brook Drive Reading, MA 01867 I6 m NON-US RECIPIENTS Blacknest Seismological Center I ATTN: Dr. P. Marshall UK</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016MS%26E..132a2005K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016MS%26E..132a2005K"><span>Angular Velocity's Neural Network Observer of the Electric Drive of TVR - <span class="hlt">IM</span> Type Implemented in Software Environment LabVIEW</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kozlova, L.; Bolovin, E.; Payuk, L.</p> <p>2016-06-01</p> <p>One of the common ways to manage a smooth starting and stopping of asynchronous motors are soft-start system. For this provision is necessary to use a closed speed asynchronous electric drive of tiristor voltage regulator - induction motor (TVR-<span class="hlt">IM</span>) type. Using real sensors significantly increases the cost of installation and also introduces a number of inconveniences in the operation of the actuator. Observer has clear advantages that are created on artificial neural network. Creating a neural network observer in program graphic programming LabVIEW will allow to evaluate the speed of rotation of the asynchronous electric.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22567951','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22567951"><span>[Pages from the history of the Department of Forensic Medicine, <span class="hlt">I.M</span>. Sechenov First Moscow State Medical University].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Leonova, E N; Romanenko, G Kh; Sidorovich, Iu V</p> <p>2012-01-01</p> <p>The history of the Department of Forensic Medicine of <span class="hlt">I.M</span>. Sechenov First Moscow State Medical University is highlighted based on the results of the studies of the relevant literature data and archival materials. The authors lay special emphasis on the organization of the teaching process and research at different stages of the development of the Department, scientific and forensic medical activities of its leading specialists, materials obtained in the course of research, and the contribution to the development of forensic medicine made by outstanding scientists.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014TCD.....8.6235M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014TCD.....8.6235M"><span>Brief Communication: 2014 velocity and flux for five major Greenland outlet glaciers using <span class="hlt">Im</span>GRAFT and Landsat-8</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Messerli, A.; Karlsson, N. B.; Grinsted, A.</p> <p>2014-12-01</p> <p>This study presents average velocity fields, mass flux estimates and central flowline profiles for five major Greenland outlet glaciers; Jakobshavn Isbræ, Nioghalvfjerdsbræ, Kangerdlugssuaq, Helheim and Petermann glaciers, spanning the period (August) 2013-(September) 2014. The results are produced by the feature tracking toolbox, <span class="hlt">Im</span>GRAFT using Landsat-8, panchromatic data. The resulting velocity fields agree with the findings of existing studies. Furthermore, our results show an unprecedented speed of over 50 m day-1 at Jakobshavn Isbræ as it continues to retreat. All the processed data will be freely available for download at http://imgraft.glaciology.net.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010obta.book..105G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010obta.book..105G"><span>The Semi-opened Infrastructure Model (Sop<span class="hlt">IM</span>): A Frame to Set Up an Organizational Learning Process</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Grundstein, Michel</p> <p></p> <p>In this paper, we introduce the "Semi-opened Infrastructure Model (Sop<span class="hlt">IM</span>)" implemented to deploy Artificial Intelligence and Knowledge-based Systems within a large industrial company. This model illustrates what could be two of the operating elements of the Model for General Knowledge Management within the Enterprise (MGKME) that are essential to set up the organizational learning process that leads people to appropriate and use concepts, methods and tools of an innovative technology: the "Ad hoc Infrastructures" element, and the "Organizational Learning Processes" element.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20806296','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20806296"><span>Mechanical properties of dense zeolitic imidazolate frameworks (ZIFs): a high-pressure X-ray diffraction, nanoindentation and computational study of the zinc framework Zn(<span class="hlt">Im</span>)2, and its lithium-boron analogue, LiB(<span class="hlt">Im</span>)4.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bennett, Thomas D; Tan, Jin-Chong; Moggach, Stephen A; Galvelis, Raimondas; Mellot-Draznieks, Caroline; Reisner, Barbara A; Thirumurugan, A; Allan, David R; Cheetham, Anthony K</p> <p>2010-09-17</p> <p>The dense, anhydrous zeolitic imidazolate frameworks (ZIFs), Zn(<span class="hlt">Im</span>)(2) (1) and LiB(<span class="hlt">Im</span>)(4) (2), adopt the same zni topology and differ only in terms of the inorganic species present in their structures. Their mechanical properties (specifically the Young's and bulk moduli, along with the hardness) have been elucidated by using high pressure, synchrotron X-ray diffraction, density functional calculations and nanoindentation studies. Under hydrostatic pressure, framework 2 undergoes a phase transition at 1.69 GPa, which is somewhat higher than the transition previously reported in 1. The Young's modulus (E) and hardness (H) of 1 (E≈8.5, H≈1 GPa) is substantially higher than that of 2 (E≈3, H≈0.1 GPa), whilst its bulk modulus is relatively lower (≈14 GPa cf. ≈16.6 GPa). The heavier, zinc-containing material was also found to be significantly harder than its light analogue. The differential behaviour of the two materials is discussed in terms of the smaller pore volume of 2 and the greater flexibility of the LiN(4) tetrathedron compared with the ZnN(4) and BN(4) units.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26526316','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26526316"><span>Predictive validity of a frailty measure (GFI) and a case complexity measure (<span class="hlt">IM</span>-E-SA) on healthcare costs in an elderly population.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Peters, Lilian L; Burgerhof, Johannes G M; Boter, Han; Wild, Beate; Buskens, Erik; Slaets, Joris P J</p> <p>2015-11-01</p> <p>Measures of frailty (Groningen Frailty Indicator, GFI) and case complexity (INTERMED for the Elderly, <span class="hlt">IM</span>-E-SA) may assist healthcare professionals to allocate healthcare resources. Both instruments have been evaluated with good psychometric properties. Limited evidence has been published about their predictive validity. Thus, our aim is to evaluate the predictive validity of both instruments on healthcare costs. Multivariate linear regression models were developed to estimate associations between the predictors frailty (GFI) and/or case complexity (<span class="hlt">IM</span>-E-SA) and the healthcare costs (in € log transformed) in the following year. All models were adjusted for demographics and the presence of morbidity. In the multivariate regression analyses the continuous scores of the GFI and <span class="hlt">IM</span>-E-SA remained significant predictors for total healthcare costs. Adjusted βs for GFI and <span class="hlt">IM</span>-E-SA were respectively 0.14 (95% CI 0.10-0.18) and 0.06 (95% CI 0.04-0.07). The corresponding explained variance (R(2)) for both models was 0.40. Frailty remained a significant predictor of long-term care costs (adjusted β 0.13 [95% CI 0.09-0.16]), while case complexity was a significant predictor of curative care costs (adjusted β 0.03 [95% CI 0.02-0.05]). The GFI and <span class="hlt">IM</span>-E-SA both accurately predict total healthcare costs in the following year. Copyright © 2015 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=179372','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=179372"><span>Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (<span class="hlt">IM</span>-2) from Streptomyces sp. strain FRI-5.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Waki, M; Nihira, T; Yamada, Y</p> <p>1997-01-01</p> <p><span class="hlt">IM</span>-2 is a butyrolactone autoregulator that controls production of blue pigment and nucleoside antibiotics in Streptomyces sp. strain FRI-5. An <span class="hlt">IM</span>-2-specific receptor gene, farA, was cloned from strain FRI-5, and nucleotide sequencing revealed that the farA gene consists of 666 bp encoding a 221-amino-acid protein of 24.3 kDa with an NH2-terminal amino acid sequence identical to that of purified native receptor. Another gene, farX, encoding a homolog of AfsA of Streptomyces griseus, was present upstream of farA. The monocistronic nature of the farA transcript was shown by Northern blot hybridization, and the transcript level increased upon addition of <span class="hlt">IM</span>-2. Recombinant FarA expressed in and purified from E. coli showed clear ligand specificity toward <span class="hlt">IM</span>-2, with a dissociation constant (Kd) for [3H]<span class="hlt">IM</span>-2-C5 of 18.2 nM. FarA showed high overall homology to BarA (virginiae butanolide receptor from S. virginiae) and ArpA (A-factor receptor from S. griseus). Sequence alignment of the three receptor proteins revealed that the NH2-terminal region containing a helix-turn-helix DNA binding motif was highly conserved. The DNA binding motif is common in procaryotic repressors of the TetR family, suggesting that all the Streptomyces autoregulator receptors may act as transcriptional repressors. PMID:9260956</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28417171','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28417171"><span>Resolution-optimized headspace gas chromatography-ion mobility spectrometry (HS-GC-<span class="hlt">IMS</span>) for non-targeted olive oil profiling.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gerhardt, Natalie; Birkenmeier, Markus; Sanders, Daniel; Rohn, Sascha; Weller, Philipp</p> <p>2017-06-01</p> <p>A prototype gas chromatography-ion mobility spectrometry (GC-<span class="hlt">IMS</span>) system, hyphenating temperature-ramped headspace GC to a modified drift time <span class="hlt">IMS</span> cell, was evaluated and compared to a conventional, isothermal capillary column (CC)-<span class="hlt">IMS</span> system on the example of the geographical differentiation of extra virgin olive oils (EVOO) from Spain and Italy. It allows orthogonal, 2D separation of complex samples and individual detection of compounds in robust and compact benchtop systems. The information from the high-resolution 3D fingerprints of volatile organic compound (VOC) fractions of EVOO samples were extracted by specifically developed chemometric MATLAB® routines to differentiate between the different olive oil provenances. A combination of unsupervised principal component analysis (PCA) with two supervised procedures, linear discriminant analysis (LDA) and k-nearest neighbors (kNN), was applied to the experimental data. The results showed very good discrimination between oils of different geographical origins, featuring 98 and 92% overall correct classification rate for PCA-LDA and kNN classifier, respectively. Furthermore, the results showed that the higher resolved 3D fingerprints obtained from the GC-<span class="hlt">IMS</span> system provide superior resolving power for non-targeted profiling of VOC fractions from highly complex samples such as olive oil. Graphical abstract Principle of the determination of geographic origins of olive oils by chemometric analysis of three-dimensional HS-GC-<span class="hlt">IMS</span> fingerprints.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3012502','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3012502"><span>Perturbing the folding energy landscape of the bacterial immunity protein <span class="hlt">Im</span>7 by site-specific N-linked glycosylation</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chen, Mark M.; Bartlett, Alice I.; Nerenberg, Paul S.; Friel, Claire T.; Hackenberger, Christian P. R.; Stultz, Collin M.; Radford, Sheena E.; Imperiali, Barbara</p> <p>2010-01-01</p> <p>N-linked glycosylation modulates protein folding and stability through a variety of mechanisms. As such there is considerable interest in the development of general rules to predict the structural consequences of site-specific glycosylation and to understand how these effects can be exploited in the design and development of modified proteins with advantageous properties. In this study, expressed protein ligation is used to create site-specifically glycosylated variants of the bacterial immunity protein <span class="hlt">Im</span>7 modified with the chitobiose disaccharide (GlcNAc-GlcNAc). Glycans were introduced at seven solvent exposed sites within the <span class="hlt">Im</span>7 sequence and the kinetic and thermodynamic consequences of N-linked glycosylation analyzed. The values for glycan incorporation were found to range from +5.2 to -3.8 kJ·mol-1. In several cases, glycosylation influences folding by modulating the local conformational preferences of the glycosylated sequence. These locally mediated effects are most prominent in the center of α-helices where glycosylation negatively effects folding and in compact turn motifs between segments of ordered secondary structure where glycosylation promotes folding and enhances the overall stability of the native protein. The studies also provide insight into why glycosylation is commonly identified at the transition between different types of secondary structure and when glycosylation may be used to elaborate protein structure to protect disordered sequences from proteolysis or immune system recognition. PMID:21148421</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20050192417','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20050192417"><span>Determination of Interlaminar Toughness of <span class="hlt">IM</span>7/977-2 Composites at Temperature Extremes and Different Thicknesses</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Johnson, W. S.; Pavlick, M. M.; Oliver, M. S.</p> <p>2005-01-01</p> <p>Composite materials are being used in the aerospace industry as a means of reducing vehicle weight. In particular, polymer matrix composites (PMC) are good candidates due to their high strength-to-weight and high stiffness-to-weight ratios. Future reusable space launch vehicles and space exploration structures will need advanced light weight composites in order to minimize vehicle weight while demonstrating robustness and durability, guaranteeing high factors of safety. In particular, the implementation of composite cryogenic propellant fuel tanks (cryotanks) for future reusable launch vehicles (RLVs) could greatly reduce the vehicle's weight versus identically sized cryotanks constructed of metallic materials. One candidate composite material for future cryotank designs is <span class="hlt">IM</span>7/977-2, which is a graphite/epoxy system. A successful candidate must demonstrate reasonable structural properties over a wide range of temperatures. Since the matrix material is normally the weak link in the composite, tests that emphasize matrix-dominated behavior need to be conducted. Therefore, the objective of this work is to determine the mode I interlaminar fracture toughness of "unidirectional" 8-ply and 16-ply <span class="hlt">IM</span>7/977-2 through experimental testing. Tests were performed at -196 degrees Celsius (-320 degrees Fahrenheit), 22 degrees Celsius (72 degrees Fahrenheit), 93 degrees Celsius (200 degrees Fahrenheit) and 160 degrees C (320 degrees Fahrenheit). Low temperature testing was completed while the specimen was submerged in a liquid nitrogen bath. High temperature testing was completed in a temperature-controlled oven.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1341744-spe-ims-ms-automated-platform-sub-sixty-second-surveillance-endogenous-metabolites-xenobiotics-biofluids','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1341744-spe-ims-ms-automated-platform-sub-sixty-second-surveillance-endogenous-metabolites-xenobiotics-biofluids"><span>SPE-<span class="hlt">IMS</span>-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Zhang, Xing; Romm, Michelle; Zheng, Xueyun; ...</p> <p>2016-12-29</p> <p>Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensitivity, efficient separation, broad dynamic range, and application to an expansive chemical space. Here in this article, we present a novel platform for small molecule analyses that addresses these requirements by combining solid-phase extraction with ion mobility spectrometry and mass spectrometry (SPE-<span class="hlt">IMS</span>-MS). This platform is capable of performing both targeted and global measurements of endogenous metabolites and xenobiotics in human biofluids with highmore » reproducibility (CV ≤ 3%), sensitivity (LODs in the pM range in biofluids) and throughput (10-s sample-to-sample duty cycle). We report application of this platform to the analysis of human urine from patients with and without type 1 diabetes, where we observed statistically significant variations in the concentration of disaccharides and previously unreported chemical isomers. Lastly, this SPE-<span class="hlt">IMS</span>-MS platform overcomes many of the current challenges of large-scale metabolomic and exposomic analyses and offers a viable option for population and patient cohort screening in an effort to gain insights into disease processes and human environmental chemical exposure.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1341744','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1341744"><span>SPE-<span class="hlt">IMS</span>-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhang, Xing; Romm, Michelle; Zheng, Xueyun; Zink, Erika M.; Kim, Young-Mo; Burnum-Johnson, Kristin E.; Orton, Daniel J.; Apffel, Alex; Ibrahim, Yehia M.; Monroe, Matthew E.; Moore, Ronald J.; Smith, Jordan N.; Ma, Jian; Renslow, Ryan S.; Thomas, Dennis G.; Blackwell, Anne E.; Swinford, Glenn; Sausen, John; Kurulugama, Ruwan T.; Eno, Nathan; Darland, Ed; Stafford, George; Fjeldsted, John; Metz, Thomas O.; Teeguarden, Justin G.; Smith, Richard D.; Baker, Erin S.</p> <p>2016-12-29</p> <p>Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensitivity, efficient separation, broad dynamic range, and application to an expansive chemical space. Here in this article, we present a novel platform for small molecule analyses that addresses these requirements by combining solid-phase extraction with ion mobility spectrometry and mass spectrometry (SPE-<span class="hlt">IMS</span>-MS). This platform is capable of performing both targeted and global measurements of endogenous metabolites and xenobiotics in human biofluids with high reproducibility (CV ≤ 3%), sensitivity (LODs in the pM range in biofluids) and throughput (10-s sample-to-sample duty cycle). We report application of this platform to the analysis of human urine from patients with and without type 1 diabetes, where we observed statistically significant variations in the concentration of disaccharides and previously unreported chemical isomers. Lastly, this SPE-<span class="hlt">IMS</span>-MS platform overcomes many of the current challenges of large-scale metabolomic and exposomic analyses and offers a viable option for population and patient cohort screening in an effort to gain insights into disease processes and human environmental chemical exposure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1149220','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1149220"><span>Insulin-induced myosin light-chain phosphorylation during receptor capping in <span class="hlt">IM</span>-9 human B-lymphoblasts.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Majercik, M H; Bourguignon, L Y</p> <p>1988-01-01</p> <p>We have examined further the interaction between insulin surface receptors and the cytoskeleton of <span class="hlt">IM</span>-9 human lymphoblasts. Using immunocytochemical techniques, we determined that actin, myosin, calmodulin and myosin light-chain kinase (MLCK) are all accumulated directly underneath insulin-receptor caps. In addition, we have now established that the concentration of intracellular Ca2+ (as measured by fura-2 fluorescence) increases just before insulin-induced receptor capping. Most importantly, we found that the binding of insulin to its receptor induces phosphorylation of myosin light chain in vivo. Furthermore, a number of drugs known to abolish the activation properties of calmodulin, such as trifluoperazine (TFP) or W-7, strongly inhibit insulin-receptor capping and myosin light-chain phosphorylation. These data imply that an actomyosin cytoskeletal contraction, regulated by Ca2+/calmodulin and MLCK, is involved in insulin-receptor capping. Biochemical analysis in vitro has revealed that <span class="hlt">IM</span>-9 insulin receptors are physically associated with actin and myosin; and most interestingly, the binding of insulin-receptor/cytoskeletal complex significantly enhances the phosphorylation of the 20 kDa myosin light chain. This insulin-induced phosphorylation is inhibited by calmodulin antagonists (e.g. TFP and W-7), suggesting that the phosphorylation is catalysed by MLCK. Together, these results strongly suggest that MLCK-mediated myosin light-chain phosphorylation plays an important role in regulating the membrane-associated actomyosin contraction required for the collection of insulin receptors into caps. Images Fig. 2. Fig. 4. PMID:3048249</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014JMEP...23..685O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014JMEP...23..685O"><span>Second- and Third-Order Elastic Constants of Filaments of HexTow® <span class="hlt">IM</span>7 Carbon Fiber</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Oliveira, L.; Hitchcock, D.; Behlow, H.; Podila, R.; Skove, M. J.; Serkiz, S. M.; Rao, A. M.</p> <p>2014-03-01</p> <p>Single filaments of HexTow® <span class="hlt">IM</span>7-12K carbon fiber were subjected to tensile measurements on a device which applies a known stress σ, and measures the resulting strain ɛ, and the change in resistivity Δρ. Young's modulus E, the resistivity ρ, the piezoresistivity Δρ/ρɛ, and the nonlinearity in the stress-strain relation δ, were determined to be 264.1 ± 16.0 GPa, 1.5 ± 0.1 × 10-3 Ω cm, 1.3 ± 0.1, and -4.96 ± 0.23, respectively. The values obtained for Young's modulus and the resistivity of the fiber are in reasonable agreement with the values reported by the manufacturer. To the best of our knowledge, this is the first report of a measurement of a third-order elastic constant of a single filament of HexTow® <span class="hlt">IM</span>7-12K. Given the high elastic strains attainable in these fibers and the negative value of δ, the usual calculation of E from a linear fit to the stress-strain data leads to an incorrect higher value of E. According to the accepted thermodynamic definition of the elastic constants, one must use the initial slope of the stress-strain curve to evaluate E. We also observed that the glue used to secure the fiber has an influence on the apparent modulus of the fiber.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4910106','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4910106"><span>Identification of structurally closely related monosaccharide and disaccharide isomers by PMP labeling in conjunction with <span class="hlt">IM</span>-MS/MS</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Yang, Hongmei; Shi, Lei; Zhuang, Xiaoyu; Su, Rui; Wan, Debin; Song, Fengrui; Li, Jinying; Liu, Shuying</p> <p>2016-01-01</p> <p>It remains particularly difficult for gaining unambiguous information on anomer, linkage, and position isomers of oligosaccharides using conventional mass spectrometry (MS) methods. In our laboratory, an ion mobility (<span class="hlt">IM</span>) shift strategy was employed to improve confidence in the identification of structurally closely related disaccharide and monosaccharide isomers using IMMS. Higher separation between structural isomers was achieved using 1-phenyl-3-methyl-5-pyrazolone (PMP) derivatization in comparison with phenylhydrazine (PHN) derivatization. Furthermore, the combination of pre-<span class="hlt">IM</span> fragmentation of PMP derivatives provided sufficient resolution to separate the isomers not resolved in the IMMS. To chart the structural variation observed in IMMS, the collision cross sections (CCSs) for the corresponding ions were measured. We analyzed nine disaccharide and three monosaccharide isomers that differ in composition, linkages, or configuration. Our data show that coexisting carbohydrate isomers can be identified by the PMP labeling technique in conjunction with ion-mobility separation and tandem mass spectrometry. The practical application of this rapid and effective method that requires only small amounts of sample is demonstrated by the successful analysis of water-soluble ginseng extract. This demonstrated the potential of this method to measure a variety of heterogeneous sample mixtures, which may have an important impact on the field of glycomics. PMID:27306514</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JEMat.tmp..712W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JEMat.tmp..712W"><span>Electronic Structure of <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) by First-Principles Calculation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wang, Jin-song; Liu, Hong-xia; Deng, Shuping; Li, De-cong; Shen, Lan-xian; Cheng, Feng; Deng, Shu-kang</p> <p>2016-10-01</p> <p>Sn-based clathrates possess excellent thermoelectric properties ascribed to their higher Seebeck coefficient and lower thermal conductivity. Guest atoms significantly modulate the thermoelectric properties of Sn-based calculates because of their diverse atomic radius and interactions with framework atoms. Thus, we explored the electronic structure of <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) by first-principles calculation. Results revealed significant differences between Yb8Ga16Sn30 and M8Ga16Sn30 (M = Ba, Sr,). In particular, the Yb-filled compound substitution possesses lowest formation energy and the off-center distance of the Yb atom is the largest compared with the other structures. <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) is an indirect band gap semiconductor, and the enhanced hybridization effect between the guest and framework atoms' orbits exists because the Yb f orbit results in a decrease in band gap. Ba- and Sr-filled clathrates have similar valence bands but slightly different conduction bands; however, Yb8Ga16Sn30 possess the spiculate density of states near the Fermi level that reveals excellent thermoelectric properties.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26007606','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26007606"><span>ESI-<span class="hlt">IMS</span>-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Young, Lydia M; Saunders, Janet C; Mahood, Rachel A; Revill, Charlotte H; Foster, Richard J; Ashcroft, Alison E; Radford, Sheena E</p> <p>2016-02-15</p> <p>Electrospray ionisation-ion mobility spectrometry-mass spectrometry (ESI-<span class="hlt">IMS</span>-MS) is a powerful method for the study of conformational changes in protein complexes, including oligomeric species populated during protein self-aggregation into amyloid fibrils. Information on the mass, stability, cross-sectional area and ligand binding capability of each transiently populated intermediate, present in the heterogeneous mixture of assembling species, can be determined individually in a single experiment in real-time. Determining the structural characterisation of oligomeric species and alterations in self-assembly pathways observed in the presence of small molecule inhibitors is of great importance, given the urgent demand for effective therapeutics. Recent studies have demonstrated the capability of ESI-<span class="hlt">IMS</span>-MS to identify small molecule modulators of amyloid assembly and to determine the mechanism by which they interact (positive, negative, non-specific binding, or colloidal) in a high-throughput format. Here, we demonstrate these advances using self-assembly of Aβ40 as an example, and reveal two new inhibitors of Aβ40 fibrillation. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016OptFT..29...90C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016OptFT..29...90C"><span>Demonstration of 2.97-Gb/s video signal transmissions in DML-based <span class="hlt">IM</span>-DDO-OFDM systems</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chen, Ming; He, Jing; Deng, Rui; Chen, Qinghui; Zhang, Jinlong; Chen, Lin</p> <p>2016-05-01</p> <p>To further investigate the feasibility of the digital signal processing (DSP) algorithms (e.g., symbol timing synchronization, channel estimation and equalization, and sampling clock frequency offset (SCFO) estimation and compensation) for real-time optical orthogonal frequency-division multiplexing (OFDM) system, 2.97-Gb/s real-time high-definition video signal parallel transmission is experimentally demonstrated in OFDM-based short-reach intensity-modulated direct-detection (<span class="hlt">IM</span>-DD) systems. The experimental results show that, in the presence of ∼12 ppm SCFO between transmitter and receiver, the adaptively modulated OFDM signal transmission over 20 km standard single-mode fiber with an error bit rate less than 1 × 10-9 can be achieved by using only DSP-based small SCFO estimation and compensation method without utilizing forward error correction technique. To the best of our knowledge, for the first time, we successfully demonstrate that the video signal at a bit rate in excess of 1-Gb/s transmission in a simple real-valued inverse fast Fourier transform and fast Fourier transform based <span class="hlt">IM</span>-DD optical OFDM system employing a directly modulated laser.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JEMat..46.2880W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JEMat..46.2880W"><span>Electronic Structure of <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) by First-Principles Calculation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wang, Jin-song; Liu, Hong-xia; Deng, Shuping; Li, De-cong; Shen, Lan-xian; Cheng, Feng; Deng, Shu-kang</p> <p>2017-05-01</p> <p>Sn-based clathrates possess excellent thermoelectric properties ascribed to their higher Seebeck coefficient and lower thermal conductivity. Guest atoms significantly modulate the thermoelectric properties of Sn-based calculates because of their diverse atomic radius and interactions with framework atoms. Thus, we explored the electronic structure of <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) by first-principles calculation. Results revealed significant differences between Yb8Ga16Sn30 and M8Ga16Sn30 (M = Ba, Sr,). In particular, the Yb-filled compound substitution possesses lowest formation energy and the off-center distance of the Yb atom is the largest compared with the other structures. <span class="hlt">I-M</span>8Ga16Sn30 (M = Ba, Sr, Yb) is an indirect band gap semiconductor, and the enhanced hybridization effect between the guest and framework atoms' orbits exists because the Yb f orbit results in a decrease in band gap. Ba- and Sr-filled clathrates have similar valence bands but slightly different conduction bands; however, Yb8Ga16Sn30 possess the spiculate density of states near the Fermi level that reveals excellent thermoelectric properties.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/14610961','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/14610961"><span>Trace explosive detection in aqueous samples by solid-phase extraction ion mobility spectrometry (SPE-<span class="hlt">IMS</span>).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Buxton, Tricia L; Harrington, Peter de B</p> <p>2003-02-01</p> <p>Law enforcement agencies use ion mobility spectrometers for the detection of explosives, drugs of abuse, and chemical warfare agents. Ion mobility spectrometry (<span class="hlt">IMS</span>) has the advantages of short analysis times, detections in the parts per billion concentrations, and high sensitivity. On-site environmental analysis of explosives or explosive residues in water is possible with ion mobility spectrometers. Unfortunately, the direct analysis of low levels of explosives in water is difficult. Extraction provides a method for pre-concentrating the analytes and removing interferents. Coupling solid-phase extraction (SPE) with <span class="hlt">IMS</span> is useful for the identification of trace amounts of explosives in water. Commercially available SPE disks were used. After extraction, the sample disk is inserted into the ion mobility spectrometer, where the analytes are thermally desorbed from the disk. Concentrations as low as one part per trillion were detected with a Barringer Ionscan 350. An external computer and acquisition software (LabVIEW, National Instruments) were used to collect data. SIMPLISMA (SIMPLe-to-use-Interactive Self-modeling Mixture Analysis) was applied to the data to resolve features that vary with respect to time.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1341744','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1341744"><span>SPE-<span class="hlt">IMS</span>-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhang, Xing; Romm, Michelle; Zheng, Xueyun; Zink, Erika M.; Kim, Young-Mo; Burnum-Johnson, Kristin E.; Orton, Daniel J.; Apffel, Alex; Ibrahim, Yehia M.; Monroe, Matthew E.; Moore, Ronald J.; Smith, Jordan N.; Ma, Jian; Renslow, Ryan S.; Thomas, Dennis G.; Blackwell, Anne E.; Swinford, Glenn; Sausen, John; Kurulugama, Ruwan T.; Eno, Nathan; Darland, Ed; Stafford, George; Fjeldsted, John; Metz, Thomas O.; Teeguarden, Justin G.; Smith, Richard D.; Baker, Erin S.</p> <p>2016-12-29</p> <p>Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensitivity, efficient separation, broad dynamic range, and application to an expansive chemical space. Here in this article, we present a novel platform for small molecule analyses that addresses these requirements by combining solid-phase extraction with ion mobility spectrometry and mass spectrometry (SPE-<span class="hlt">IMS</span>-MS). This platform is capable of performing both targeted and global measurements of endogenous metabolites and xenobiotics in human biofluids with high reproducibility (CV ≤ 3%), sensitivity (LODs in the pM range in biofluids) and throughput (10-s sample-to-sample duty cycle). We report application of this platform to the analysis of human urine from patients with and without type 1 diabetes, where we observed statistically significant variations in the concentration of disaccharides and previously unreported chemical isomers. Lastly, this SPE-<span class="hlt">IMS</span>-MS platform overcomes many of the current challenges of large-scale metabolomic and exposomic analyses and offers a viable option for population and patient cohort screening in an effort to gain insights into disease processes and human environmental chemical exposure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19960023558','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19960023558"><span>Processing and Properties of Fiber Reinforced Polymeric Matrix Composites. Part 2; Processing Robustness of <span class="hlt">IM</span>7/PETI Polyimide Composites</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Hou, Tan-Hung</p> <p>1996-01-01</p> <p>The processability of a phenylethynyl terminated imide (PETI) resin matrix composite was investigated. Unidirectional prepregs were made by coating an N-methylpyrrolidone solution of the amide acid oligomer onto unsized <span class="hlt">IM</span>7. Two batches of prepregs were used: one was made by NASA in-house, and the other was from an industrial source. The composite processing robustness was investigated with respect to the effect of B-staging conditions, the prepreg shelf life, and the optimal processing window. Rheological measurements indicated that PETI's processability was only slightly affected over a wide range of B-staging temperatures (from 250 C to 300 C). The open hole compression (OHC) strength values were statistically indistinguishable among specimens consolidated using various B-staging conditions. Prepreg rheology and OHC strengths were also found not to be affected by prolonged (i.e., up to 60 days) ambient storage. An optimal processing window was established using response surface methodology. It was found that <span class="hlt">IM</span>7/PETI composite is more sensitive to the consolidation temperature than to the consolidation pressure. A good consolidation was achievable at 371 C/100 Psi, which yielded an OHC strength of 62 Ksi at room temperature. However, processability declined dramatically at temperatures below 350 C.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25526592','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25526592"><span>Rapid and accurate detection of urinary pathogens by mobile <span class="hlt">IMS</span>-based electronic nose: a proof-of-principle study.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Roine, Antti; Saviauk, Taavi; Kumpulainen, Pekka; Karjalainen, Markus; Tuokko, Antti; Aittoniemi, Janne; Vuento, Risto; Lekkala, Jukka; Lehtimäki, Terho; Tammela, Teuvo L; Oksala, Niku K J</p> <p>2014-01-01</p> <p>Urinary tract infection (UTI) is a common disease with significant morbidity and economic burden, accounting for a significant part of the workload in clinical microbiology laboratories. Current clinical chemisty point-of-care diagnostics rely on imperfect dipstick analysis which only provides indirect and insensitive evidence of urinary bacterial pathogens. An electronic nose (eNose) is a handheld device mimicking mammalian olfaction that potentially offers affordable and rapid analysis of samples without preparation at athmospheric pressure. In this study we demonstrate the applicability of ion mobility spectrometry (<span class="hlt">IMS</span>) -based eNose to discriminate the most common UTI pathogens from gaseous headspace of culture plates rapidly and without sample preparation. We gathered a total of 101 culture samples containing four most common UTI bacteries: E. coli, S. saprophyticus, E. faecalis, Klebsiella spp and sterile culture plates. The samples were analyzed using ChemPro 100i device, consisting of <span class="hlt">IMS</span> cell and six semiconductor sensors. Data analysis was conducted by linear discriminant analysis (LDA) and logistic regression (LR). The results were validated by leave-one-out and 5-fold cross validation analysis. In discrimination of sterile and bacterial samples sensitivity of 95% and specificity of 97% were achieved. The bacterial species were identified with sensitivity of 95% and specificity of 96% using eNose as compared to urine bacterial cultures. These findings strongly demonstrate the ability of our eNose to discriminate bacterial cultures and provides a proof of principle to use this method in urinanalysis of UTI.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..14.1366G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..14.1366G"><span>The Applicability of Incoherent Array Processing to <span class="hlt">IMS</span> Seismic Array Stations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gibbons, S. J.</p> <p>2012-04-01</p> <p> nuclear tests but, due to signal incoherence, failed to contribute to the automatic event detections. It is demonstrated that the smoothed incoherent slowness estimates for the MJAR Pn phases for both tests indicate unambiguously the correct type of phase and a backazimuth estimate within 5 degrees of the great-circle backazimuth. The detection part of the algorithm is applicable to all <span class="hlt">IMS</span> arrays, and spectrogram-based processing may offer a reduction in the false alarm rate for high frequency signals. Significantly, the local maxima of the scalar functions derived from the transformed spectrogram beams provide good estimates of the signal onset time. High frequency energy is of greater significance for lower event magnitudes and in, for example, the cavity decoupling detection evasion scenario. There is a need to characterize propagation paths with low attenuation of high frequency energy and situations in which parameter estimation on array stations fails.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22592813','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22592813"><span>Direct infusion electrospray ionization-ion mobility high resolution mass spectrometry (DIESI-<span class="hlt">IM</span>-HRMS) for rapid characterization of potential bioprocess streams.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Munisamy, Sharon M; Chambliss, C Kevin; Becker, Christopher</p> <p>2012-07-01</p> <p>Direct infusion electrospray ionization - ion mobility - high resolution mass spectrometry (DIESI-<span class="hlt">IM</span>-HRMS) has been utilized as a rapid technique for the characterization of total molecular composition in "whole-sample" biomass hydrolysates and extracts. <span class="hlt">IM</span>-HRMS data reveal a broad molecular weight distribution of sample components (up to 1100 m/z) and provide trendline isolation of feedstock components from those introduced "in process." Chemical formulas were obtained from HRMS exact mass measurements (with typical mass error less than 5 ppm) and were consistent with structural carbohydrates and other lignocellulosic degradation products. Analyte assignments are supported via <span class="hlt">IM</span>-MS collision-cross-section measurements and trendline analysis (e.g., all carbohydrate oligomers identified in a corn stover hydrolysate were found to fall within 6% of an average trendline). These data represent the first report of collision cross sections for several negatively charged carbohydrates and other acidic species occurring natively in biomass hydrolysates.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27603100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27603100"><span>Reproducible Synthesis and High Porosity of mer-Zn(<span class="hlt">Im</span>)2 (ZIF-10): Exploitation of an Apparent Double-Eight Ring Template.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ramirez, Joseph R; Yang, Haiyang; Kane, Christopher M; Ley, Amanda N; Holman, K Travis</p> <p>2016-09-21</p> <p>Reproducible synthesis of the elusive merlinoite (mer) topology of zinc imidazolate (mer-Zn(<span class="hlt">Im</span>)2, or ZIF-10) has been achieved by employing a simple macrocyclic solute-MeMeCH2-as a kinetic template. The corresponding phase-pure material, mer-MeMeCH2@Zn16(<span class="hlt">Im</span>)32, is confirmed to be porous and exhibits one of the highest experimental surface areas (1893 m(2)/g, BET) yet reported for any ZIF. The X-ray single crystal structure of mer-MeMeCH2@Zn16(<span class="hlt">Im</span>)32·xsolvent reveals the role of the macrocyle as an 8-fold hydrogen bond acceptor in templating the requisite double-eight rings (d8r) of the mer framework.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28141835','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28141835"><span>Structural Determinants of Health among <span class="hlt">Im</span>/Migrants in the Indoor Sex Industry: Experiences of Workers and Managers/Owners in Metropolitan Vancouver.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Goldenberg, Shira M; Krüsi, Andrea; Zhang, Emma; Chettiar, Jill; Shannon, Kate</p> <p>2017-01-01</p> <p>Globally, <span class="hlt">im</span>/migrant women are overrepresented in the sex industry and experience disproportionate health inequities. Despite evidence that the health impacts of migration may vary according to the timing and stage of migration (e.g., early arrival vs. long-term migration), limited evidence exists regarding social and structural determinants of health across different stages of migration, especially among <span class="hlt">im</span>/migrants engaged in sex work. Our aim was to describe and analyze the evolving social and structural determinants of health and safety across the arrival and settlement process for <span class="hlt">im</span>/migrants in the indoor sex industry. We analyzed qualitative interviews conducted with 44 <span class="hlt">im</span>/migrant sex workers and managers/owners working in indoor sex establishments (e.g., massage parlours, micro-brothels) in Metropolitan Vancouver, Canada in 2011; quantitative data from AESHA, a larger community-based cohort, were used to describe socio-demographic and social and structural characteristics of <span class="hlt">im</span>/migrant sex workers. Based on quantitative data among 198 <span class="hlt">im</span>/migrant workers in AESHA, 78.3% were Chinese-born, the median duration in Canada was 6 years, and most (86.4%) serviced clients in formal indoor establishments. Qualitative narratives revealed diverse pathways into sex work upon arrival to Canada, including language barriers to conventional labour markets and the higher pay and relative flexibility of sex work. Once engaged in sex work, fear associated with police raids (e.g., immigration concerns, sex work disclosure) and language barriers to sexual negotiation and health, social and legal supports posed pervasive challenges to health, safety and human rights during long-term settlement in Canada. Findings highlight the critical influences of criminalization, language barriers, and stigma and discrimination related to sex work and <span class="hlt">im</span>/migrant status in shaping occupational health and safety for <span class="hlt">im</span>/migrants engaged in sex work. Interventions and policy reforms that emphasize</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5283672','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5283672"><span>Structural Determinants of Health among <span class="hlt">Im</span>/Migrants in the Indoor Sex Industry: Experiences of Workers and Managers/Owners in Metropolitan Vancouver</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Krüsi, Andrea; Zhang, Emma; Chettiar, Jill; Shannon, Kate</p> <p>2017-01-01</p> <p>Background Globally, <span class="hlt">im</span>/migrant women are overrepresented in the sex industry and experience disproportionate health inequities. Despite evidence that the health impacts of migration may vary according to the timing and stage of migration (e.g., early arrival vs. long-term migration), limited evidence exists regarding social and structural determinants of health across different stages of migration, especially among <span class="hlt">im</span>/migrants engaged in sex work. Our aim was to describe and analyze the evolving social and structural determinants of health and safety across the arrival and settlement process for <span class="hlt">im</span>/migrants in the indoor sex industry. Methods We analyzed qualitative interviews conducted with 44 <span class="hlt">im</span>/migrant sex workers and managers/owners working in indoor sex establishments (e.g., massage parlours, micro-brothels) in Metropolitan Vancouver, Canada in 2011; quantitative data from AESHA, a larger community-based cohort, were used to describe socio-demographic and social and structural characteristics of <span class="hlt">im</span>/migrant sex workers. Results Based on quantitative data among 198 <span class="hlt">im</span>/migrant workers in AESHA, 78.3% were Chinese-born, the median duration in Canada was 6 years, and most (86.4%) serviced clients in formal indoor establishments. Qualitative narratives revealed diverse pathways into sex work upon arrival to Canada, including language barriers to conventional labour markets and the higher pay and relative flexibility of sex work. Once engaged in sex work, fear associated with police raids (e.g., immigration concerns, sex work disclosure) and language barriers to sexual negotiation and health, social and legal supports posed pervasive challenges to health, safety and human rights during long-term settlement in Canada. Conclusions Findings highlight the critical influences of criminalization, language barriers, and stigma and discrimination related to sex work and <span class="hlt">im</span>/migrant status in shaping occupational health and safety for <span class="hlt">im</span>/migrants engaged in sex work</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26926438','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26926438"><span>Proteomic MALDI-TOF/TOF-<span class="hlt">IMS</span> examination of peptide expression in the formalin fixed brainstem and changes in sudden infant death syndrome infants.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hunt, Nicholas J; Phillips, Leo; Waters, Karen A; Machaalani, Rita</p> <p>2016-04-14</p> <p>Matrix assisted laser desorption/ionisation imaging mass spectrometry (MALDI-<span class="hlt">IMS</span>) has not previously been utilised to examine sudden infant death syndrome (SIDS). This study aimed to optimise MALDI <span class="hlt">IMS</span> for use on archived formalin-fixed-paraffin-embedded human infant medulla tissue (n=6, controls; n=6, SIDS) to evaluate differences between multiple nuclei of the medulla by using high resolution <span class="hlt">IMS</span>. Profiles were compared between SIDS and age/sex matched controls. LC-MALDI identified 55 proteins based on 321 peptides across all samples; 286 peaks were found using <span class="hlt">IMS</span>, corresponding to these 55 proteins that were directly compared between controls and SIDS. Control samples were used to identify common peptides for neuronal/non-neuronal structures allowing identification of medullary regions. In SIDS, abnormal expression patterns of 41 peptides (p≤0.05) corresponding to 9 proteins were observed; these changes were confirmed with immunohistochemistry. The protein abnormalities varied amongst nuclei, with the majority of variations in the raphe nuclei, hypoglossal and pyramids. The abnormal proteins are not related to a previously identified neurological disease pathway but consist of developmental neuronal/glial/axonal growth, cell metabolism, cyto-architecture and apoptosis components. This suggests that SIDS infants have abnormal neurological development in the raphe nuclei, hypoglossal and pyramids of the brainstem, which may contribute to the pathogenesis of SIDS. This study is the first to perform an imaging mass spectrometry investigation in the human brainstem and also within sudden infant death syndrome (SIDS). LC MALDI and MALDI <span class="hlt">IMS</span> identified 55 proteins based on 285 peptides in both control and SIDS tissue; with abnormal expression patterns present for 41/285 and 9/55 proteins in SIDS using <span class="hlt">IMS</span>. The abnormal proteins are critical for neurological development; with the impairment supporting the hypothesis that SIDS may be due to delayed neurological</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.S11C2462K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.S11C2462K"><span>Is there evidence for an acoustic signal at <span class="hlt">IMS</span> infrasound stations from the North Korean event of 12 May 2010?</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Koch, K.; Pilger, C.</p> <p>2016-12-01</p> <p>Over the last two years more and more evidence has been presented that a small seismic event had occurred in North Korea on 12 May 2010. Most recent work has concluded that the event shows earthquake-like features when applying event identification methods based on regional phase amplitude ratios. These findings are in contrast to previous hypotheses and identification studies which claimed that low-yield nuclear testing had been carried out. Some of these studies were based solely on radionuclide and noble gas detections found at International Monitoring System (<span class="hlt">IMS</span>) stations as well as at national facilities. Turning to another technology, it has been shown in several studies that underground nuclear tests carried out at the Punggye-ri test site in North Korea have produced infrasound signatures at the closest <span class="hlt">IMS</span> stations I45RU and I30JP and at national infrasound stations in South Korea. In particular this holds for the tests carried out in 2009, 2013 and 2016. For the 2013 test infrasound arrivals have been included in the Reviewed Event Bulletin (REB) issued by the International Data Center of CTBTO. Based on this experience an effort was undertaken to analyze infrasound data from these <span class="hlt">IMS</span> stations and to search for signals that may be associated to the 12 May 2010 event. While it is not expected to obtain such a signal for an earthquake source at depth, as would not be expected as well for a buried explosion source of rather small magnitude, the analysis of I45RU and I30JP data suggests a very weak arrival as obtained from frequency-wavenumber analysis showing parameters similar to those obtained for the announced tests. If the features found are indeed not artifacts then one could speculate that (1) the event of concern may not be an earthquake, even though it exhibits seismic signal characteristics causing it to be classified as an earthquake, or (2) the detections may be related to incidental blasting activity in nearby quarries. Propagation modeling of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012A%26A...544A.131M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012A%26A...544A.131M"><span>Direct imaging of extra-solar planets in star forming regions. Lessons learned from a false positive around <span class="hlt">IM</span> Lupi</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mawet, D.; Absil, O.; Montagnier, G.; Riaud, P.; Surdej, J.; Ducourant, C.; Augereau, J.-C.; Röttinger, S.; Girard, J.; Krist, J.; Stapelfeldt, K.</p> <p>2012-08-01</p> <p>Context. Most exoplanet imagers consist of ground-based adaptive optics coronagraphic cameras which are currently limited in contrast, sensitivity and astrometric precision, but advantageously observe in the near-infrared window (1-5 μm). Because of these practical limitations, our current observational aim at detecting and characterizing planets puts heavy constraints on target selection, observing strategies, data reduction, and follow-up. Most surveys so far have thus targeted young systems (1-100 Myr) to catch the putative remnant thermal radiation of giant planets, which peaks in the near-infrared. They also favor systems in the solar neighborhood (d < 80 pc), which eases angular resolution requirements but also ensures a good knowledge of the distance and proper motion, which are critical to secure the planet status, and enable subsequent characterization. Aims: Because of their youth, it is very tempting to target the nearby star forming regions, which are typically twice as far as the bulk of objects usually combed for planets by direct imaging. Probing these interesting reservoirs sets additional constraints that we review in this paper by presenting the planet search that we initiated in 2008 around the disk-bearing T Tauri star <span class="hlt">IM</span> Lup, which is part of the Lupus star forming region (140-190 pc). Methods: We show and discuss why age determination, the choice of evolutionary model for both the central star and the planet, precise knowledge of the host star proper motion, relative or absolute (between different instruments) astrometric accuracy (including plate scale calibration), and patience are the key ingredients for exoplanet searches around more distant young stars. Results: Unfortunately, most of the time, precision and perseverance are not paying off: we discovered a candidate companion around <span class="hlt">IM</span> Lup in 2008, which we report here to be an unbound background object. We nevertheless review in details the lessons learned from our endeavor, and</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28454588','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28454588"><span>A case matched study examining the reliability of using <span class="hlt">Im</span>PACT to assess effects of multiple concussions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Barker, Trevor; Russo, Stephen A; Barker, Gaytri; Rice, Mark A; Jeffrey, Mary G; Broderick, Gordon; Craddock, Travis J A</p> <p>2017-04-28</p> <p>Approximately 3.8 million sport and recreational concussions occur per year, creating a need for accurate diagnosis and management of concussions. Researchers and clinicians are exploring the potential dose-response cumulative effects of concussive injuries using computerized neuropsychological exams, however, results have been mixed and/or contradictory. This study starts with a large adolescent population and applies strict inclusion criteria to examine how previous mild traumatic brain injuries affect symptom reports and neurocognitive performance on the Immediate Post-concussion Assessment and Cognitive Testing (<span class="hlt">Im</span>PACT) computerized tool. After applying exclusion criteria and case matching, 204 male and 99 female participants remained. These participants were grouped according to sex and the number of previous self-reported concussions and examined for overall differences on symptoms reported and scores obtained on the <span class="hlt">Im</span>PACT neurocognitive battery composites. In an effort to further reduce confounding factors due to the varying group sizes, participants were then case matched on age, sex, and body mass index and analyzed for differences on symptoms reported and scores obtained on the <span class="hlt">Im</span>PACT neurocognitive battery composites. Case matched analysis demonstrated males with concussions experience significantly higher rates of dizziness (p = .027, η(2) = .035), fogginess (p = .038, η(2) = .032), memory problems (p = .003, η(2) = .055), and concentration problems (p = .009, η(2) = .046) than males with no reported previous concussions. No significant effects were found for females, although females reporting two concussions demonstrated a slight trend for experiencing higher numbers of symptoms than females reporting no previous concussions. The results suggest that male adolescent athletes reporting multiple concussions have lingering concussive symptoms well after the last concussive event; however, these symptoms were found to</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EPJP..130...88N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EPJP..130...88N"><span>A comparative study between a high-gain interconnected observer and an adaptive observer applied to <span class="hlt">IM</span>-based WECS</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Naifar, Omar; Boukettaya, Ghada; Oualha, Abdelmajid; Ouali, Abderrazak</p> <p>2015-05-01</p> <p>This paper is devoted to the investigation of the potentialities of induction motor sensorless strategies in speed control applications. A comparison study is carried out between two observation approaches dedicated to speed control strategies of induction machine (<span class="hlt">IM</span>)-based wind energy conversion systems (WECS) under parametric variations, such as: i) the adaptive observer approach, which is based on the speed adaptation law and ii) the interconnected observer, that offers robustness and stability of the system with reduced CPU time. The comparison study is achieved considering four performance criteria: stability, robustness with respect to the variations of the machine inductances, robustness with respect to the variations of the machine resistances, feasibility of the torque estimation. It has been found that the introduced interconnected observer exhibits a higher performance than the traditional adaptive one, with respect to the above-cited comparison criteria.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25934125','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25934125"><span>Ultrasound intensification suppresses the need of methanol excess during the biodiesel production with Lipozyme TL-<span class="hlt">IM</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Subhedar, Preeti B; Botelho, Claudia; Ribeiro, Artur; Castro, Rita; Pereira, Maria Alcina; Gogate, Parag R; Cavaco-Paulo, Artur</p> <p>2015-11-01</p> <p>The synthesis of biodiesel from sunflower oil and methanol based on transesterification using the immobilized lipase from Thermomyces lanuginosus (Lipozyme TL-<span class="hlt">IM</span>) has been investigated under silent conditions and under an ultrasound field. Ultrasound assisted process led to reduced processing time and requirement of lower enzyme dosage. We found for the first time that oil to methanol ratio of 1:3 was favored for the ultrasound assisted enzymatic process which is lower than that observed for the case of conventional stirring based approach (ratio of 1.4). Our results indicate that intensification provided by ultrasound suppresses the need of the excess of the methanol reactant during the enzymatic biodiesel production. Ultrasound assisted enzymatic biodiesel production is therefore a faster and a cleaner processes.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000BAAA...44...49G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000BAAA...44...49G"><span>Errores fotométricos debido al uso del filtro anular de mediana en <span class="hlt">im</span>ágenes CCD</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gil-Hutton, R.; Cañada, M.; Noel, N.</p> <p></p> <p>El filtro anular de mediana tiene la importante propiedad de tener una escala claramente definida, lo que permite remover de una imagen CCD todos los objetos con tamaños menores a esta escala, independientemente de su morfología particular, y reemplazarlos por el correspondiente ``background" local. Este filtro es de gran utilidad para remover gradientes de fondo, ``fringing" y halos de objetos extendidos mediante el simple procedimiento de restar a la imagen original una imagen filtrada, repitiendo el proceso las veces que sea necesario. En este trabajo se presentan resultados sobre los errores que introduce este filtro en la fotometría de objetos con diferente relación S/N y su aplicación a <span class="hlt">im</span>ágenes con gradientes de fondo y ``fringing".</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016OptCo.380..154G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016OptCo.380..154G"><span>Design and performance investigation of LDPC-coded upstream transmission systems in <span class="hlt">IM</span>/DD OFDM-PONs</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gong, Xiaoxue; Guo, Lei; Wu, Jingjing; Ning, Zhaolong</p> <p>2016-12-01</p> <p>In Intensity-Modulation Direct-Detection (<span class="hlt">IM</span>/DD) Orthogonal Frequency Division Multiplexing Passive Optical Networks (OFDM-PONs), aside from Subcarrier-to-Subcarrier Intermixing Interferences (SSII) induced by square-law detection, the same laser frequency for data sending from Optical Network Units (ONUs) results in ONU-to-ONU Beating Interferences (OOBI) at the receiver. To mitigate those interferences, we design a Low-Density Parity Check (LDPC)-coded and spectrum-efficient upstream transmission system. A theoretical channel model is also derived, in order to analyze the detrimental factors influencing system performances. Simulation results demonstrate that the receiver sensitivity is improved 3.4 dB and 2.5 dB under QPSK and 8QAM, respectively, after 100 km Standard Single-Mode Fiber (SSMF) transmission. Furthermore, the spectrum efficiency can be improved by about 50%.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27410115','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27410115"><span>OFDM and PAM comparison using a high baudrate low resolution <span class="hlt">IM</span>/DD interface for 400G Ethernet access.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>André, Nuno Sequeira; Louchet, Hadrien; Filsinger, Volker; Hansen, Erik; Richter, André</p> <p>2016-05-30</p> <p>We compare OFDM and PAM for 400G Ethernet based on a 3-bit high baudrate <span class="hlt">IM</span>/DD interface at 1550nm. We demonstrate 27Gb/s and 32Gb/s transmission over 10km SSMF using OFDM and PAM respectively. We show that capacity can be improved through adaptation/equalization to achieve 42Gb/s and 64Gb/s for OFDM and PAM respectively. Experimental results are used to create realistic simulations to extrapolate the performance of both modulation formats under varied conditions. For the considered interface we found that PAM has the best performance, OFDM is impaired by quantization noise. When the resolution limitation is relaxed, OFDM shows better performance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/5380076','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/5380076"><span><span class="hlt">IM</span>-GEO: Impact of R and D on cost of geothermal power: Documentation of Model Version 2. 09</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Petty, S.; Entingh, D.; Livesay, B.J.</p> <p>1988-02-01</p> <p><span class="hlt">IM</span>-GEO is an analysis used to estimate the impact of technology improvements on the relative cost of hydrothermal power. The analysis is available in a tutorial program for use on personal computers. It is designed for use by R and D program managers to evaluate R and D options. Only the potential impact of technologies is considered with all economic factors being held constant. This analysis has one unique feature. The economic impact of reducing risk by improving reservoir characterization is included using a strategy currently employed by financial institutions. This report describes the basis of the calculations, documents the code, and describes the operational procedures. Application of the code to study potential cost reductions due to R and D success will be done by R and D managers to evaluate and direct their own programs.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <center> <div class="footer-extlink text-muted"><small>Some links on this page may take you to non-federal websites. 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