48 CFR 237.104 - Personal services contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... procedures do not apply to contracts awarded to business entities other than individuals. Selections made... intelligence component or counter-intelligence organization of DoD; or (iii) Directly support the mission of... travel between home or place of business and official duty station. (iii) Coordinate with the civilian...

75 FR 6685 - Section 8 Housing Assistance Payments Program-Contract Rent Annual Adjustment Factors, Fiscal...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... contract rent is reduced by comparability): The Table 1 Contract Rent AAF is used for a unit occupied by a... rent to owner will not be reduced below the contract rent on the effective date of the HAP contract. III. When to Use Reduced Contract Rent AAFs (From Contract Rent AAF Table 2) In accordance with...

48 CFR 209.104-1 - General standards.

Code of Federal Regulations, 2011 CFR

2011-10-01

... International Contracting, OUSD(AT&L)DPAP(CPIC)), 3060 Defense Pentagon, Washington, DC 20301-3060. (ii....104-1 General standards. (e) For cost-reimbursement or incentive type contracts, or contracts which...; (iii) Risk of misallocations and mischarges are minimized; and (iv) Contract allocations and charges...

24 CFR 246.8 - Materials to be submitted to HUD in support of preemption request.

Code of Federal Regulations, 2011 CFR

2011-04-01

... separate breakdown of rent loss due to tenant turnover for the past 2 years. (6) A certified statement... by the following: (i) Tax rates or appraisals, (ii) Utility rates, (iii) Contracts for employees or... appraisals, (ii) Utility rates, (iii) Contracts for employees or services, (iv) Insurance. If there are none...

[Prognostic value of chosen parameters of mechanical and bioelectrical uterine activity in prediction of threatening preterm labour].

PubMed

Zietek, Jerzy; Sikora, Jerzy; Horoba, Krzysztof; Matonia, Adam; Jezewski, Janusz; Magnucki, Jacek; Kobielska, Lucyna

2009-03-01

To record and analyse bioelectrical activity of the uterine muscle in the course of physiological pregnancy, labour and threatening premature labour; to define which parameters from the analysis of both electrohysterogram and mechanical activity signal allow us to predict threatening premature labour. Material comprised 62 pregnant women: Group I--27 patients in their first physiological pregnancy, Group II--21 patients in their first pregnancy with symptoms of threatening premature labour, and Group III--14 patients in the first labour period. The on-line analysis of the mechanical (TOCO) and electrical (EHG) contraction activity relied on determination of quantitative parameters of detected uterine contractions. The obtained statistical results demonstrated a possibility to differentiate between Group I and II through the amplitude and contraction area for EHG signal, and only the contraction amplitude for TOCO signal. Additionally, significant differentiating parameters for electrohysterogram are: contraction power and its median frequency. Analyzing Group I and III, significant differences were noted for contraction amplitude and area obtained both from EHG and TOCO signals. Similarly, the contraction power (from EHG) enables us to assign the contractions either to records from Group I or to labour type. There was no significant difference noted between Group II and III. Identification of pregnant women at risk of premature labour should lead to their inclusion in rigorous perinatal surveillance. This requires novel, more sensitive methods that are able to detect early symptoms of the uterine contraction activity increase. Electrohysterography provides complete information on principles of bioelectrical uterine activity. Quantitative parameters of EHG analysis enable the detection of records (contractions) with the symptoms of premature uterine contraction activity.

12 CFR Appendix A to Subpart A of... - Minimum Capital Components for Interest Rate and Foreign Exchange Rate Contracts

Code of Federal Regulations, 2010 CFR

2010-01-01

... sheet interest rate and foreign exchange rate contracts: a. Interest Rate Contracts i. Single currency... Contracts i. Cross-currency interest rate swaps. ii. Forward foreign exchange rate contracts. iii. Currency... exposure is zero. Mark-to-market values are measured in United States dollars, regardless of the currency...

KSC SBIR/STTR 2004 Program Year Report

NASA Technical Reports Server (NTRS)

2005-01-01

The Kennedy Space Center Level III SBIR/STTR management staff is under the Technology Transfer Office within the Spaceport Engineering and Technology Directorate. The SBIR and STTR programs provide an opportunity for small high technology companies and research institutions to participate in Government-sponsored research and development (R&D) programs in key technology areas. The SBIR program was established by Congress in 1982 to provide increased opportunities for small businesses to participate in R&D programs, increase employment, and improve U.S. competitiveness. The program's specific objectives are to stimulate U.S. technological innovation, use small businesses to meet Federal research and development needs, increase private sector commercialization of innovations, and foster and encourage participation by socially disadvantaged businesses. Legislation enacted in December 2000 reauthorized the program and strengthened emphasis on pursuing commercial applications of SBIR projects. An SBIR Phase I contract is the opportunity to establish the feasibility and technical merit of a proposed innovation. Selected competitively, the Phase I contract lasts for 6 months and is funded up to $70,000. SBIR Phase II contracts continue the most promising Phase I projects based on scientific! technical merit, expected value to NASA, company capability, and commercial potential. Phase II contracts are usually for a period of 24 months and may not exceed $600,000. NASA usually selects approximately 40 percent of Phase I projects to continue to the Phase II level. Phase III is the process of furthering the development of a product to make it commercially available. The STTR program awards contracts to small business concerns for cooperative R&D with a nonprofit research institution. Research institutions include nonprofit research organizations, Federal laboratories, or universities. The goal of the program established by Congress is to facilitate the transfer of technology developed by a research institution through the entrepreneurship of a small business. The STIR program is smaller in funding than the SBIR program. While the proposal is submitted by the small business concern, at least 30 percent of the funding and work must originate with the research institution. STTR Phase I projects receive up to $100K for a one-year effort, and a Phase II contract receives up to $600K for two years.

48 CFR 215.408 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY....215-11, Price Reduction for Defective Cost or Pricing Data—Modifications; (ii) FAR 52.215-12, Subcontractor Cost or Pricing Data; or (iii) FAR 52.215-13, Subcontractor Cost or Pricing Data—Modifications. (2...

17 CFR 48.7 - Requirements for registration.

Code of Federal Regulations, 2014 CFR

2014-04-01

... to detect trading and market abuses and to reconstruct all transactions within a reasonable period of... contract market; (ii) Contracts must be cleared; (iii) Contracts must not be prohibited from being traded... regulation of the foreign board of trade, the clearing organization, and the type of contracts to be made...

17 CFR 48.7 - Requirements for registration.

Code of Federal Regulations, 2013 CFR

2013-04-01

... to detect trading and market abuses and to reconstruct all transactions within a reasonable period of... contract market; (ii) Contracts must be cleared; (iii) Contracts must not be prohibited from being traded... regulation of the foreign board of trade, the clearing organization, and the type of contracts to be made...

17 CFR 48.7 - Requirements for registration.

Code of Federal Regulations, 2012 CFR

2012-04-01

... to detect trading and market abuses and to reconstruct all transactions within a reasonable period of... contract market; (ii) Contracts must be cleared; (iii) Contracts must not be prohibited from being traded... regulation of the foreign board of trade, the clearing organization, and the type of contracts to be made...

24 CFR 1710.16 - Regulatory exemption-determination required.

Code of Federal Regulations, 2011 CFR

2011-04-01

...) Specifies the developer's and purchaser's responsibilities for providing and maintaining roads, water and... in which the roads, water and sewer facilities and promised amenities will be completed; (iii... spouse makes a personal on-the-lot inspection of the lot to be purchased before signing a contract. (4...

IVHS Countermeasures For Rear-End Collisions, Task 1 Volume Iii: 1991 Nass Cds Case Analysis, Interim Report

DOT National Transportation Integrated Search

1994-02-01

THE ATTACHED REPORT IS FROM THE NHTSA SPONSORED PROGRAM, "IVHS COUNTERMEASURES FOR REAR-END COLLISIONS," CONTRACT #DTNH22-93-C-07326. THE PROGRAM'S PRIMARY OBJECTIVE IS TO DEVELOP PRACTICAL PERFORMANCE GUIDELINES OR SPECIFICATIONS FOR REAR-END COLLIS...

History of the Voluntary Intermodal Sealift Agreement

DTIC Science & Technology

2002-06-01

reflect executed Voluntary Enrollment Contracts (VEC) for VISA Stages I, II, and III to include basic activation procedures; DOD annual minimums for...provisions; and on-the-shelf basic agreements (such as VISA Intermodal Contingency Contracts (VICC) for Stages I, II, and III). The anticipated...insufficient Program incentives are revised annually, but the basic tenets remain in place. Activation, capacity required to commit and carrier risk clauses

Changes of Serum Calcium Concentration, Frequency of Ruminal Contraction and Feed Intake Soon after Parturition of Dairy Cows Fed Difructose Anhydride III.

PubMed

Wynn, S; Teramura, M; Sato, T; Hanada, M

2015-01-01

Requirements to control the large decrease in serum calcium (Ca) due to parturition and to increase the feed intake soon after parturition have been well accepted in dairy cows. This study was aimed to investigate the feed intake affected by serum Ca concentration with difructose anhydride (DFA) III supplement in dairy cows soon after parturition. Fourteen transition Holstein cows were divided into DFA and control (CONT) groups within 1 to 5 parity variations in each group. Measurement schedule for an individual cow was from 14 d before parturition to 7 d following parturition. The cows in DFA group were supplied 0.2 kg/head/d of DFA III feed containing 40 g of pure DFA III while the cows in CONT group received no DFA III. Other feeding procedures were the same for all cows in both groups. At parturition (d 0), serum Ca concentration sharply declined in both groups (p<0.05). Time interval for recovery from decreased serum Ca to its normal range (>9.0 mg/dL) tended to be faster in DFA group (12 h) than in the CONT group (48 h), but the differences were not significant. Active ruminal contraction was observed in DFA group at following parturition of d 1 (p<0.05), d 3 (p<0.05), and d 5 (p<0.01). Dry matter (DM) intake did not differ between the groups. However, positive correlations were observed between serum Ca concentration and ruminal contraction (p<0.001), and between ruminal contraction and DM intake (p<0.001) during following parturition. According to multiple regression analysis (R(2) = 0.824, p<0.001), the DM intake was positively affected by serum Ca concentration and ruminal contraction. These results suggest that feed intake soon after parturition in dairy cows can be increased by improvement of serum Ca concentration and active ruminal contraction, but DFA III supplementation in this study did not improve the lower serum Ca concentration due to parturition.

Changes of Serum Calcium Concentration, Frequency of Ruminal Contraction and Feed Intake Soon after Parturition of Dairy Cows Fed Difructose Anhydride III

PubMed Central

Wynn, S.; Teramura, M.; Sato, T.; Hanada, M.

2015-01-01

Requirements to control the large decrease in serum calcium (Ca) due to parturition and to increase the feed intake soon after parturition have been well accepted in dairy cows. This study was aimed to investigate the feed intake affected by serum Ca concentration with difructose anhydride (DFA) III supplement in dairy cows soon after parturition. Fourteen transition Holstein cows were divided into DFA and control (CONT) groups within 1 to 5 parity variations in each group. Measurement schedule for an individual cow was from 14 d before parturition to 7 d following parturition. The cows in DFA group were supplied 0.2 kg/head/d of DFA III feed containing 40 g of pure DFA III while the cows in CONT group received no DFA III. Other feeding procedures were the same for all cows in both groups. At parturition (d 0), serum Ca concentration sharply declined in both groups (p<0.05). Time interval for recovery from decreased serum Ca to its normal range (>9.0 mg/dL) tended to be faster in DFA group (12 h) than in the CONT group (48 h), but the differences were not significant. Active ruminal contraction was observed in DFA group at following parturition of d 1 (p<0.05), d 3 (p<0.05), and d 5 (p<0.01). Dry matter (DM) intake did not differ between the groups. However, positive correlations were observed between serum Ca concentration and ruminal contraction (p<0.001), and between ruminal contraction and DM intake (p<0.001) during following parturition. According to multiple regression analysis (R2 = 0.824, p<0.001), the DM intake was positively affected by serum Ca concentration and ruminal contraction. These results suggest that feed intake soon after parturition in dairy cows can be increased by improvement of serum Ca concentration and active ruminal contraction, but DFA III supplementation in this study did not improve the lower serum Ca concentration due to parturition. PMID:25557676

7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...

7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...

7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...

40 CFR 725.205 - Persons who may report under this subpart.

Code of Federal Regulations, 2014 CFR

2014-07-01

... which a commercial entity contracts directly with a university or researcher; or (ii) Situations in... commercial funding for the purpose of developing a commercial application; or (iii) The researcher or university has sought or is seeking a patent to protect a commercial application which the research is...

40 CFR 725.205 - Persons who may report under this subpart.

Code of Federal Regulations, 2012 CFR

2012-07-01

... which a commercial entity contracts directly with a university or researcher; or (ii) Situations in... commercial funding for the purpose of developing a commercial application; or (iii) The researcher or university has sought or is seeking a patent to protect a commercial application which the research is...

40 CFR 725.205 - Persons who may report under this subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... which a commercial entity contracts directly with a university or researcher; or (ii) Situations in... commercial funding for the purpose of developing a commercial application; or (iii) The researcher or university has sought or is seeking a patent to protect a commercial application which the research is...

Joint Air-to-Surface Standoff Missile (JASSM)

DTIC Science & Technology

2013-12-01

LRIP Decision/Contract Award JAN 2001 JAN 2001 JAN 2002 DEC 2001 Lot II Contract Award JAN 2002 JAN 2002 JAN 2003 NOV 2002 RAA /B-52 SEP 2002 SEP 2002...SEP 2003 SEP 2003 Milestone III OCT 2003 OCT 2003 JUL 2004 APR 2004 RAA /F-16 DEC 2003 DEC 2003 DEC 2004 DEC 2004 IOC/F/A-18 E/F JUN 2009 N/A N/A N/A...Engineering and Manufacturing Development PDRR - Program Definition and Risk Reduction RAA - Required Assets Available JASSM-ER Milestones SAR Baseline Prod

76 FR 14421 - Section 8 Housing Assistance Payments Program-Contract Rent Annual Adjustment Factors (AAFs...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-16

... contract rent is reduced by comparability): The Table 1 Contract Rent AAF is used for a unit occupied by a... be reduced below the contract rent on the effective date of the HAP contract. III. When To Use Reduced AAFs (From AAF Table 2) In accordance with Section 8(c)(2)(A) of the United States Housing Act of...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

Financial constraints in capacity planning: a national utility regulatory model (NUREG). Volume III of III: software description. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1981-10-29

This volume is the software description for the National Utility Regulatory Model (NUREG). This is the third of three volumes provided by ICF under contract number DEAC-01-79EI-10579. These three volumes are: a manual describing the NUREG methodology; a users guide; and a description of the software. This manual describes the software which has been developed for NUREG. This includes a listing of the source modules. All computer code has been written in FORTRAN.

48 CFR 19.708 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract clauses. 19.708 Section 19.708 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC.... (iii) The contract action will not be reported in the Federal Procurement Data System pursuant to 4.606...

Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries

PubMed Central

Prieto-Lloret, Jesus; Snetkov, Vladimir A.; Shaifta, Yasin; Docio, Inmaculada; Connolly, Michelle J.; MacKay, Charles E.; Knock, Greg A.

2018-01-01

Application of H2S (“sulfide”) elicits a complex contraction in rat pulmonary arteries (PAs) comprising a small transient contraction (phase 1; Ph1) followed by relaxation and then a second, larger, and more sustained contraction (phase 2; Ph2). We investigated the mechanisms causing this response using isometric myography in rat second-order PAs, with Na2S as a sulfide donor. Both phases of contraction to 1,000 μM Na2S were attenuated by the pan-PKC inhibitor Gö6983 (3 μM) and by 50 μM ryanodine; the Ca2+ channel blocker nifedipine (1 μM) was without effect. Ph2 was attenuated by the mitochondrial complex III blocker myxothiazol (1 μM), the NADPH oxidase (NOX) blocker VAS2870 (10 μM), and the antioxidant TEMPOL (3 mM) but was unaffected by the complex I blocker rotenone (1 μM). The bath sulfide concentration, measured using an amperometric sensor, decreased rapidly following Na2S application, and the peak of Ph2 occurred when this had fallen to ~50 μM. Sulfide caused a transient increase in NAD(P)H autofluorescence, the offset of which coincided with development of the Ph2 contraction. Sulfide also caused a brief mitochondrial hyperpolarization (assessed using tetramethylrhodamine ethyl ester), followed immediately by depolarization and then a second more prolonged hyperpolarization, the onset of which was temporally correlated with the Ph2 contraction. Sulfide application to cultured PA smooth muscle cells increased reactive oxygen species (ROS) production (recorded using L012); this was absent when the mitochondrial flavoprotein sulfide-quinone oxoreductase (SQR) was knocked down using small interfering RNA. We propose that the Ph2 contraction is largely caused by SQR-mediated sulfide metabolism, which, by donating electrons to ubiquinone, increases electron production by complex III and thereby ROS production. PMID:29351439

Effect of amoxicillin/clavulanate on gastrointestinal motility in children.

PubMed

Gomez, Roberto; Fernandez, Sergio; Aspirot, Ann; Punati, Jaya; Skaggs, Beth; Mousa, Hayat; Di Lorenzo, Carlo

2012-06-01

The aim of the present study was to evaluate the effect of amoxicillin/clavulanate (A/C) on gastrointestinal motility. Twenty consecutive pediatric patients referred for antroduodenal manometry received 20 mg/kg of A/C into the small bowel lumen. In 10 patients (group A), A/C was given 1 hour after and in 10 (group B), 1 hour before ingestion of a meal. Characteristics of the migrating motor complex, including presence, frequency, amplitude, and propagation of duodenal phase III and phase I duration and phase II motility index (MI), were evaluated 30 minutes before and after A/C administration. There were no statistically significant differences in age and sex between the 2 groups. Manometry studies were considered normal in 8 patients in each group. In group A, 2 patients developed duodenal phase III after receiving A/C, and no significant difference was found in the MI before and after the drug administration. In group B, 9 patients developed duodenal phase III (P <0.05 vs group A). All phase III occurred within a few minutes from the medication administration. Most duodenal phase III contractions were preceded by an antral component during fasting but never after the medication was administered in either of the 2 groups (P<0.001 vs fasting). In group B, the duration of duodenal phase I was shorter after drug administration (P<0.05). There was no significant difference in duodenal phase II MI before and after A/C administration for the 2 study groups. In children, administration of A/C directly into the small bowel before a meal induces phase III-type contractions in the duodenum, with characteristics similar to those present in the fasting state. These data suggest the possible use of A/C as a prokinetic agent. Further studies are needed to clarify its specific mechanism of action and the group of patients most likely to benefit from its use.

48 CFR 204.7003 - Basic PII number.

Code of Federal Regulations, 2011 CFR

2011-10-01

... procurement instrument is issued or awarded. (3) Position 9. Indicate the type of instrument by entering one...) Invitations for bids—B (iii) Contracts of all types except indefinite delivery contracts, sales contracts, and...—N (xv) Do not use—O (xvi) Purchase order—automated (assign V when numbering capacity of P is...

26 CFR 1.752-1 - Treatment of partnership liabilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., obligations under a short sale, and obligations under derivative financial instruments such as options, forward contracts, futures contracts, and swaps. (iii) Other liabilities. For obligations that are not § 1...

7 CFR 1465.25 - Contract violations and termination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... prevented compliance with the contract. If the participant claims hardship, that claim must be well... is in the public interest. (iii) In carrying out NRCS' role in this section, NRCS may consult with...

25 CFR 535.1 - Amendments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS POST-APPROVAL PROCEDURES... management contract for the operation of a class II or class III gaming activity. (b) A tribe shall submit an... information required under § 537.1(b)(1) of this chapter for class II gaming contracts or § 537.1(b)(1)(i) of...

48 CFR 52.212-4 - Contract Terms and Conditions-Commercial Items.

Code of Federal Regulations, 2010 CFR

2010-10-01

... issue a demand for payment to the Contractor upon finding a debt is due under the contract. (iii) Final... days; (B) The Contractor fails to liquidate a debt previously demanded by the Contracting Officer within the timeline specified in the demand for payment unless the amounts were not repaid because the...

48 CFR 15.407-1 - Defective certified cost or pricing data.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracting officer shall immediately bring the matter to the attention of the prospective contractor, whether... bring the character of the data to the attention of the contracting officer; (iii) The contract was... change order). (5) An offset shall be allowed only in an amount supported by the facts and if the...

Quantitative option analysis for implementation and management of landfills.

PubMed

Kerestecioğlu, Merih

2016-09-01

The selection of the most feasible strategy for implementation of landfills is a challenging step. Potential implementation options of landfills cover a wide range, from conventional construction contracts to the concessions. Montenegro, seeking to improve the efficiency of the public services while maintaining affordability, was considering privatisation as a way to reduce public spending on service provision. In this study, to determine the most feasible model for construction and operation of a regional landfill, a quantitative risk analysis was implemented with four steps: (i) development of a global risk matrix; (ii) assignment of qualitative probabilities of occurrences and magnitude of impacts; (iii) determination of the risks to be mitigated, monitored, controlled or ignored; (iv) reduction of the main risk elements; and (v) incorporation of quantitative estimates of probability of occurrence and expected impact for each risk element in the reduced risk matrix. The evaluated scenarios were: (i) construction and operation of the regional landfill by the public sector; (ii) construction and operation of the landfill by private sector and transfer of the ownership to the public sector after a pre-defined period; and (iii) operation of the landfill by the private sector, without ownership. The quantitative risk assessment concluded that introduction of a public private partnership is not the most feasible option, unlike the common belief in several public institutions in developing countries. A management contract for the first years of operation was advised to be implemented, after which, a long term operating contract may follow. © The Author(s) 2016.

DCAA Audits: Widespread Problems with Audit Quality Require Significant Reform

DTIC Science & Technology

2009-09-01

is included in appendix III. DOD contract management continues to be a high- risk area for the government.17 With hundreds of billions of taxpayer...Defense Contract Management : DOD’s Lack of Adherence to Key Contracting Principles on Iraq Oil Contract Put Government Interests at Risk , GAO-07-839...in the Federal Government68 require federal agency managers to identify and assess relevant risks the agency faces from external and internal

48 CFR 233.215 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

48 CFR 233.215 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

48 CFR 233.215 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

48 CFR 233.215 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

48 CFR 233.215 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

A dihydropyridine receptor alpha1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor.

PubMed

Cui, Yanfang; Tae, Han-Shen; Norris, Nicole C; Karunasekara, Yamuna; Pouliquin, Pierre; Board, Philip G; Dulhunty, Angela F; Casarotto, Marco G

2009-03-01

The II-III loop of the dihydropyridine receptor (DHPR) alpha(1s) subunit is a modulator of the ryanodine receptor (RyR1) Ca(2+) release channel in vitro and is essential for skeletal muscle contraction in vivo. Despite its importance, the structure of this loop has not been reported. We have investigated its structure using a suite of NMR techniques which revealed that the DHPR II-III loop is an intrinsically unstructured protein (IUP) and as such belongs to a burgeoning structural class of functionally important proteins. The loop does not possess a stable tertiary fold: it is highly flexible, with a strong N-terminal helix followed by nascent helical/turn elements and unstructured segments. Its residual structure is loosely globular with the N and C termini in close proximity. The unstructured nature of the II-III loop may allow it to easily modify its interaction with RyR1 following a surface action potential and thus initiate rapid Ca(2+) release and contraction. The in vitro binding partner for the II-III was investigated. The II-III loop interacts with the second of three structurally distinct SPRY domains in RyR1, whose function is unknown. This interaction occurs through two preformed N-terminal alpha-helical regions and a C-terminal hydrophobic element. The A peptide corresponding to the helical N-terminal region is a common probe of RyR function and binds to the same SPRY domain as the full II-III loop. Thus the second SPRY domain is an in vitro binding site for the II-III loop. The possible in vivo role of this region is discussed.

77 FR 22340 - Section 8 Housing Assistance Payments Program-Annual Adjustment Factors, Fiscal Year 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... of comparability. In all other cases (i.e., unless the contract rent is reduced by comparability... level will be the new rent to owner. The new rent to owner will not be reduced below the contract rent on the effective date of the HAP contract. III. When To Use Reduced AAFs (From AAF Table 2) In...

75 FR 39301 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-08

...,000 contracts. Payments would be made at the stated rate for each tier for those contracts that fall... increasing the per contract rate on the Tier II and Tier III levels. The Exchange still continues to afford the members [sic] organizations who transact volume in Tier I a benefit as well. Amending the...

77 FR 49049 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-15

... for Non-ISE Market Maker \\6\\ orders, (iii) $0.30 per contract for Firm Proprietary/Broker-Dealer and... in the Select Symbols from $0.29 per contract to $0.32 per contract, (ii) Non-ISE Market Maker orders... not they are meeting the Exchange's stated criteria. \\6\\ A Non-ISE Market Maker, or Far Away Market...

78 FR 24265 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... transaction fees and provides rebates to market participants that add or remove liquidity from the Exchange...: (i) $0.32 per contract for Market Maker \\4\\ and Market Maker Plus \\5\\ orders, (ii) $0.36 per contract for Non-ISE Market Maker \\6\\ orders, (iii) $0.33 per contract for Firm Proprietary/Broker-Dealer and...

Research Methods to Develop Measures of Effectiveness of the United States Coast Guard’s Vessel Inspection and Boarding Program. Decision Support for Utilizing Measures of Effectiveness - Volume III

DTIC Science & Technology

1995-05-01

Eubank S.E. Albuquerque, NM 87123 Christopher Rodriguez Kevin Downer U.S. Coast Guard Research and Development Center 1082 Shennecossett Road Groton...standard, specifica )e n. ’OVVELOPj4 Commanding Officer United States Coast Guard Research & Development Center 1082 Shennecossett Road SGroton, CT...Work Unit No. (TRAIS) U.S. Coast Guard Sandia National Laboratories Research and Development Center 11. Contract or Grant No. 1515 Eubank SE 1082

Age 60 study, part III : consolidated database experiments final report.

DOT National Transportation Integrated Search

1994-10-01

This document is one of four products completed as a part of the Age 60 Rule research contract monitored by Pam Della Rocco, Civil Aerospace Medical Institute, Contracting Officer's Technical Representative. This work was performed. This report was a...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

Lower energy and pulse stacking. A safer alternative for skin tightening using fractional CO2 laser.

PubMed

Motta, Marcos Matias; Stelini, Rafael Fantelli; Calderoni, Davi Reis; Gilioli, Rovilson; Kharmandayan, Paulo

2016-01-01

To evaluate the effect of different energies and stacking in skin shrinkage. Three decreasing settings of a fractional CO2 laser were applied to the abdomen of Twenty five Wistar rats divided into three groups. Group I (n=5) was histologically evaluated for microthermal zones dimensions. Groups II and III (n=10 each) were macroscopic evaluated with freeware ImageJ for area contraction immediately and after 30 and 60 days. No statistical significance was found within microthermal zone histological dimensions (Group I) in all settings studied. (Ablation depth: 76.90 to 97.18µm; Coagulation depth: 186.01 to 219.84 µm). In Group II, macroscopic evaluation showed that all settings cause significant immediate skin contraction. The highest setting cause significant more intense tightening effect initially, contracting skin area from 258.65 to 179.09 mm2. The same pattern was observed in Group III. At 30 and 60 days, the lowest setting significantly sustained contraction. Lower fractional CO2 laser energies associated to pulse stacking could cause consistent and long lasting tissue contraction in rats.

12 CFR 1010.109 - Title to the property and land use.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., language in the disclosure narrative under “Method of Sale”: “If you fail to make your payments required by the contract, you may lose your lot and all monies paid.” (iii) If, at the time of a credit sale, the developer gives the buyer a deed to the lot, what type of security must the buyer give the seller? (iv) If...

12 CFR 1010.109 - Title to the property and land use.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., language in the disclosure narrative under “Method of Sale”: “If you fail to make your payments required by the contract, you may lose your lot and all monies paid.” (iii) If, at the time of a credit sale, the developer gives the buyer a deed to the lot, what type of security must the buyer give the seller? (iv) If...

12 CFR 1010.109 - Title to the property and land use.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., language in the disclosure narrative under “Method of Sale”: “If you fail to make your payments required by the contract, you may lose your lot and all monies paid.” (iii) If, at the time of a credit sale, the developer gives the buyer a deed to the lot, what type of security must the buyer give the seller? (iv) If...

30MM GAU-8/A Plastic Frangible Projectile

DTIC Science & Technology

1977-03-01

20. ABSTRACT fContlnuo on rmvert» tld» 11 nacaaaary and Idontlly by block numbmr) ■feA 30mm target practice (TP) projectile, designed to break...contract to solve these problems. As a result, the Air Force has decided to delay further development of this projectile design concept...Section Title I INTRODUCTION II TECHNICAL DISCUSSION Design Parameters Final Projectile Design Design Evolution Acceptance Testing III

Datacomputer and SIP Operations

DTIC Science & Technology

1979-03-30

developed in 1977 under ARPA Contract No. N0001 i4-76-C-0991 , as an application package which would utilize the Datacomputer [ Dorin & Sattley] for...Datacomputer Cambridge, Massachusetts, [ DORIN & EASTLAKE] R. H. Darin and Donald E. Eastlake, III; "Use of the Datacomputer in the Vela Seismological... DORIN & SATTLEY] Dorin , R.H. and Sattl^y, J.Z. Databases: Final Technical Report, Report No. CCAr.77-10, Computer America, 575

7 CFR 766.110 - Conservation Contract.

Code of Federal Regulations, 2010 CFR

2010-01-01

... floodplains; (iii) Areas of high water quality or scenic value; (iv) Historic or cultural properties listed in..., or 50 years. (e) Conservation management plan. The Agency, through the recommendations of the Conservation Contract review team, is responsible for approving the conservation management plan. (f...

7 CFR 766.110 - Conservation Contract.

Code of Federal Regulations, 2011 CFR

2011-01-01

... floodplains; (iii) Areas of high water quality or scenic value; (iv) Historic or cultural properties listed in..., or 50 years. (e) Conservation management plan. The Agency, through the recommendations of the Conservation Contract review team, is responsible for approving the conservation management plan. (f...

48 CFR 3.1103 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Contractor Employees Performing Acquisition Functions 3.1103 Procedures. (a) By use of the contract clause at... employees perform acquisition functions closely associated with inherently Government functions to— (1) Have... information accessed through performance of a Government contract for personal gain; and (iii) Obtain a signed...

48 CFR 3.1103 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Contractor Employees Performing Acquisition Functions 3.1103 Procedures. (a) By use of the contract clause at... employees perform acquisition functions closely associated with inherently Government functions to— (1) Have... information accessed through performance of a Government contract for personal gain; and (iii) Obtain a signed...

48 CFR 3.1103 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Contractor Employees Performing Acquisition Functions 3.1103 Procedures. (a) By use of the contract clause at... employees perform acquisition functions closely associated with inherently Government functions to— (1) Have... information accessed through performance of a Government contract for personal gain; and (iii) Obtain a signed...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT.... Government under surplus sales contracts; (iii) Designated by the Department of Defense as ineligible...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... surplus sales contracts; (iii) Designated by the Department of Defense as ineligible, debarred, or...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT.... Government under surplus sales contracts; (iii) Designated by the Department of Defense as ineligible...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... surplus sales contracts; (iii) Designated by the Department of Defense as ineligible, debarred, or...

15 CFR Supplement No. 2 to Part 742 - Anti-Terrorism Controls: North Korea, Syria and Sudan Contract Sanctity Dates and Related Policies

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Robots capable of employing feedback information in real time processing to generate or modify programs...-uses in Syria will be considered on a case-by case basis. (A) Contract sanctity date for such robots... Supplement. (B) Contract sanctity date for all other such robots: August 28, 1991. (iii) Sudan. Applications...

15 CFR Supplement No. 2 to Part 742 - Anti-Terrorism Controls: North Korea, Syria and Sudan Contract Sanctity Dates and Related Policies

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Robots capable of employing feedback information in real time processing to generate or modify programs...-uses in Syria will be considered on a case-by case basis. (A) Contract sanctity date for such robots... Supplement. (B) Contract sanctity date for all other such robots: August 28, 1991. (iii) Sudan. Applications...

15 CFR Supplement No. 2 to Part 742 - Anti-Terrorism Controls: North Korea, Syria and Sudan Contract Sanctity Dates and Related Policies

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Robots capable of employing feedback information in real time processing to generate or modify programs...-uses in Syria will be considered on a case-by case basis. (A) Contract sanctity date for such robots... Supplement. (B) Contract sanctity date for all other such robots: August 28, 1991. (iii) Sudan. Applications...

15 CFR Supplement No. 2 to Part 742 - Anti-Terrorism Controls: North Korea, Syria and Sudan Contract Sanctity Dates and Related Policies

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Robots capable of employing feedback information in real time processing to generate or modify programs...-uses in Syria will be considered on a case-by case basis. (A) Contract sanctity date for such robots... Supplement. (B) Contract sanctity date for all other such robots: August 28, 1991. (iii) Sudan. Applications...

Stirling convertor performance mapping test results

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Peterson, Allen A.; White, Maurice A.; Faultersack, Franklyn; Redinger, Darin L.; Petersen, Stephen L.

2002-01-01

The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. Recent TDC performance data are provided in this paper, together with predictions from Stirling simulation models. .

48 CFR 246.407 - Nonconforming supplies or services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance... the material, or perform the service, at no cost to the Government; and (iii) May accept consideration... design control activity is the approval authority for acceptance of any nonconforming aviation or ship...

Brownfield Action III - Modular use of hydrogeology instruction in the virtual classroom

NASA Astrophysics Data System (ADS)

Bower, P.; Liddicoat, J.

2009-04-01

Brownfield Action III (BA III) is a network-based, interactive, digital space and simulation developed by Barnard College and the Columbia Center for New Media Teaching and Learning in which students explore and solve problems in environmental forensics. BA III is a proven inquiry-based approach to teaching and learning that, since its inception in 1999, has been recognized as an exemplary curriculum. Indeed, in 2002 it was selected as a national model curriculum by SENCER (Science Education for New Civic Engagements and Responsibilities). BA III provides instruction in environmental site assessments and in the remediation of former industrial sites (brownfields) for secondary and higher education students. The initial full-semester, three hours of weekly laboratory instruction that complements lectures in BA II has been revised for modular use in Hydrology, Environmental Science, and Environmental Ethics undergraduate and graduate courses in the United States. The remediation of brownfields is important because they have potential as recreational, residential, and commercial real estate sites. As part of determining the value of such a site, an environmental site assessment (ESA) is required to determine the nature and extent of any contamination. To reach that objective, BA III contains a narrative that is embedded and to be discovered in simulation; it is a story of groundwater contamination complete with underground contaminant plumes in a fictitious town with buildings, roads, wells, water tower, homes, and businesses as well as a municipal government with relevant historical documents. Student companies work collaboratively in teams of two, sign a contract with a development corporation to conduct a Phase One ESA, receive a realistic budget, and compete with other teams to fulfill the contract while maximizing profit. To reach a valid conclusion in the form of a professional-level ESA and 3-D maps of the physical site, teams construct a detailed narrative from diverse forms of information, including socio-historical and a scientific dataset comprised of over 2,000,000 data points. BA III forces students to act on their perceptions of the interlocking realms of knowledge, theory and practical experience, providing an opportunity for them to gain valuable practice at tackling the complexity and ambiguity of a large-scale, interdisciplinary investigation of groundwater contamination and environmental forensics.

48 CFR 232.503-15 - Application of Government title terms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...

48 CFR 232.503-15 - Application of Government title terms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...

48 CFR 232.503-15 - Application of Government title terms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...

48 CFR 232.503-15 - Application of Government title terms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... place in the prior month; and (iii) The summary report includes as a minimum, the total number and...

48 CFR 232.503-15 - Application of Government title terms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... place in the prior month; and (iii) The summary report includes as a minimum, the total number and...

A Description of the Ship Combat System Simulation

DTIC Science & Technology

1984-09-01

developed by NWC, NOSC, NSWC, and CACI, Inc. SCSS is supported by naval and industrial laboratories throughout the country. The users of the...34’. 1lhutlon/ *A i ~n o 1. * Ruido i/iI NSWC TR 84-182 CONTENTS Page INTRODUCTION................................ .. . . .. . .. .. .. ... 1 SIMULATION...Isuch as a contract), Navy or private industry , can obtain the mulation by becoming a member of this Users’ Group. Additional information garding the

41 CFR 105-50.101 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Purpose. 105-50.101 Section 105-50.101 Public Contracts and Property Management Federal Property Management Regulations System... provisions of Title III of the Intergovernmental Cooperation Act of 1968 (82 Stat. 1102, 42 U.S.C. 4221-4225...

77 FR 50121 - Office of Direct Service and Contracting Tribes National Indian Health Outreach and Education...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-20

... Contracting Tribes National Indian Health Outreach and Education Program Funding Opportunity Announcement Type... Education (NIHOE-III) program funding opportunity that includes outreach and education activities on the... Health Care and Education Reconciliation Act of 2010, Public Law 111- 152, collectively known as the...

A Laboratory Study Investigating the Feasibility of Applying Calcite-Type Coatings to Segregated Ballast Tanks

DTIC Science & Technology

1981-08-01

A LABORATORY STUDY INVESTIGATIING THE FEASIBILITY OF APPLYING CALCITE -TYPE COATINGS TO SEGREGATED BALLAST TANKS AUGUST, 1981 Prepared by: Ocean City...Laboratory Study Investigating The Feasibility of Applying Calcite -Type Coatings to Segregated Ballast Tanks 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Executive Summary List of Figures I. Conclusions II. Introduction III. Background-The Development and Use of Calcite -Type Coatings IV. Experimental

Evaluation of DCS III Transmission Alternatives, Phase II, Task 1.

DTIC Science & Technology

1981-08-31

Agency Defense Communications Engineering Center Reston, Virginia 22090 Contract No. DCA 100-79-C--0044 ,D ii 2 01982 ONG SPACI IAE K ROONOO IIACH...Transmission Media Alternatives Task 2. Development of Evolving DCS Transmission System Al ternatives Task 3. Identification of Technology and Regulatory...For existing tree growth, add 15 m. For smaller vegetation, add 3 m. 11. Determine the antenna tower heights to insure line-of-sight clearance above the

78 FR 67188 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... production method. 1206.259(c)(1)(ii) and (c)(2)(iii). Submit arm's-length and non- AUDIT PROCESS (See Note...-length AUDIT PROCESS (See Note). transportation contracts, production agreements, operating agreements...-length AUDIT PROCESS (See Note). power plant contracts, production and operating agreements and related...

48 CFR 13.302-2 - Unpriced purchase orders.

Code of Federal Regulations, 2010 CFR

2010-10-01

... may be used only when— (1) It is impractical to obtain pricing in advance of issuance of the purchase... readily be established; or (iii) Supplies or services for which prices are known to be competitive, but... office shall follow up on each order to ensure timely pricing. The contracting officer or the contracting...

26 CFR 1.408(q)-1 - Deemed IRAs in qualified employer plans.

Code of Federal Regulations, 2011 CFR

2011-04-01

... governing instrument creating the trust must satisfy the requirements of section 408(a) (1), (2), (3), (4... accounts of any of the deemed IRAs is invested in life insurance contracts, regardless of whether the separate account for the qualified employer plan invests in life insurance contracts. (iii) Separate...

26 CFR 1.408(q)-1 - Deemed IRAs in qualified employer plans.

Code of Federal Regulations, 2010 CFR

2010-04-01

... governing instrument creating the trust must satisfy the requirements of section 408(a) (1), (2), (3), (4... accounts of any of the deemed IRAs is invested in life insurance contracts, regardless of whether the separate account for the qualified employer plan invests in life insurance contracts. (iii) Separate...

Isometric and dynamic strength and neuromuscular attributes as predictors of vertical jump performance in 11- to 13-year-old male athletes.

PubMed

McKinlay, Brandon John; Wallace, Phillip J; Dotan, Raffy; Long, Devon; Tokuno, Craig; Gabriel, David A; Falk, Bareket

2017-09-01

In explosive contractions, neural activation is a major factor in determining the rate of torque development, while the latter is an important determinant of jump performance. However, the contribution of neuromuscular activation and rate of torque development to jump performance in children and youth is unclear. The purpose of this study was to examine the relationships between the rate of neuromuscular activation, peak torque, rate of torque development, and jump performance in young male athletes. Forty-one 12.5 ± 0.5-year-old male soccer players completed explosive, unilateral isometric and dynamic (240°/s) knee extensions (Biodex System III), as well as countermovement-, squat-, and drop-jumps. Peak torque (pT), peak rate of torque development (pRTD), and rate of vastus lateralis activation (Q 30 ) during the isometric and dynamic contractions were examined in relation to attained jump heights. Isometric pT and pRTD were strongly correlated (r = 0.71) but not related to jump performance. Dynamic pT and pRTD, normalized to body mass, were significantly related to jump height in all 3 jumps (r = 0.38-0.66, p < 0.05). Dynamic normalized, but not absolute pRTD, was significantly related to Q 30 (r = 0.35, p < 0.05). In young soccer players, neuromuscular activation and rate of torque development in dynamic contractions are related to jump performance, while isometric contractions are not. These findings have implications in the choice of training and assessment methods for young athletes.

Human Rehabilitation Techniques. Contract Papers. Volume III, Part B.

ERIC Educational Resources Information Center

Ross, E. C.; And Others

Volume III, Section B of a six-volume final report (which covers the findings of a research project on policy and technology related to rehabilitation of disabled individuals) presents four papers which examine important rehabilitation-oriented issues. In the first paper, "Transportation Problems of Persons with Disabilities--The Federal Response"…

Advanced flight hardware for organic separations

NASA Astrophysics Data System (ADS)

Deuser, Mark S.; Vellinger, John C.; Weber, John T.

1997-01-01

Aqueous Two-Phase Partitioning (ATPP) is a unique separation technique which allows purification and classification of biological materials. SHOT has employed the ATPP process in separation equipment developed for both space and ground applications. Initial equipment development and research focused on the ORganic SEParation (ORSEP) space flight experiments that were performed on suborbital rockets and the shuttle. ADvanced SEParations (ADSEP) technology was developed as the next generation of ORSEP equipment through a NASA Small Business Innovation Research (SBIR) contract. Under the SBIR contract, a marketing study was conducted, indicating a growing commercial market exists among biotechnology firms for ADSEP equipment and associated flight research and development services. SHOT is preparing to begin manufacturing and marketing laboratory versions of the ADSEP hardware for the ground-based market. In addition, through a self-financed SBIR Phase III effort, SHOT fabricated and integrated the ADSEP flight hardware for a commercially-driven flight experiment as the initial step in marketing space processing services. The ADSEP ground-based and microgravity research is expected to play a vital role in developing important new biomedical and pharmaceutical products.

77 FR 65034 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-24

... that trade against Priority Customer orders in the Select Symbols, SPY, Non-Select Penny Pilot Symbols...,\\8\\ Firm Proprietary/Broker-Dealer and Professional Customer \\9\\ orders; (ii) $0.20 per contract for Non-ISE Market Maker \\10\\ orders; and (iii) $0.00 per contract for Priority Customer \\11\\ orders. For...

26 CFR 1.148-1 - Definitions and elections.

Code of Federal Regulations, 2010 CFR

2010-04-01

...). Annuity contract means annuity contract as defined in section 72. Available amount means available amount as defined in § 1.148-6(d)(3)(iii). Bona fide debt service fund means a fund, which may include... defined in section 1273(a)(1)) or premium on an obligation— (i) An amount that does not exceed 2 percent...

48 CFR 234.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... accordance with 234.201(1)(iii) and (iv)— (1) Use the provision at 252.234-7001, Notice of Earned Value... solicitation; and (2) Use the clause at 252.234-7002, Earned Value Management System, instead of the clause at... ACQUISITION Earned Value Management System 234.203 Solicitation provisions and contract clause. For cost or...

75 FR 67258 - Position Reports for Physical Commodity Swaps

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... Cattle. CME Milk Class III. Comex (``CMX'') Copper Grade 1. CMX Gold. CMX Silver. ICE Futures US (``ICUS... Oats. CME Butter. CME Cheese. CME Dry Whey. CME Hardwood Pulp. CME Lean Hogs. CME Non Fat Dry Milk. CME... contract--The ICE WTI Average Price Option is indirectly linked to a 20.2 listed futures contract because...

SERC 2014 2018 Technical Plan: 2016 Update

DTIC Science & Technology

2016-02-18

Contract Number: HQ0034-13-D-0004 February 18, 2016 SERC 2014-2018 Technical Plan Update SERC 2014-2018 Technical Plan: 2016 Update...UNCLASSIFIED / APPROVED FOR PUBLIC RELEASE Contract Number: HQ0034-13-D-0004 February 18, 2016 SERC 2014-2018 Technical Plan Update ii...18, 2016 SERC 2014-2018 Technical Plan Update iii TABLE OF CONTENTS Table of Contents

17 CFR Appendix A to Part 151 - Spot-Month Position Limits

Code of Federal Regulations, 2014 CFR

2014-04-01

... Contract Referencedcontract spot- month limit Agricultural Referenced Contracts ICE Futures U.S. Cocoa 1,000 ICE Futures U.S. Coffee C 500 Chicago Board of Trade Corn 600 ICE Futures U.S. Cotton No. 2 300 ICE Futures U.S. FCOJ-A 300 Chicago Mercantile Exchange Class III Milk 1,500 Chicago Mercantile...

77 FR 31680 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... Plus; (iii) Non-ISE Market Maker; \\5\\ (iv) Firm Proprietary; (v) Customer (Professional);\\6\\ (vi) Priority Customer,\\7\\ 100 or more contracts; and (vii) Priority Customer, less than 100 contracts. \\3... Market Makers'' collectively. See ISE Rule 100(a)(25). \\5\\ A Non-ISE Market Maker, or Far Away Market...

14 CFR 91.23 - Truth-in-leasing clause requirement in leases and conditional sales contracts.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aircraft Registration Branch, Attn: Technical Section, P.O. Box 25724, Oklahoma City, OK 73125; (2) A copy... the airport of departure; (ii) The departure time; and (iii) The registration number of the aircraft... contract of conditional sale involving a U.S.-registered large civil aircraft and entered into after...

14 CFR 91.23 - Truth-in-leasing clause requirement in leases and conditional sales contracts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aircraft Registration Branch, Attn: Technical Section, P.O. Box 25724, Oklahoma City, OK 73125; (2) A copy... the airport of departure; (ii) The departure time; and (iii) The registration number of the aircraft... contract of conditional sale involving a U.S.-registered large civil aircraft and entered into after...

14 CFR 91.23 - Truth-in-leasing clause requirement in leases and conditional sales contracts.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aircraft Registration Branch, Attn: Technical Section, P.O. Box 25724, Oklahoma City, OK 73125; (2) A copy... the airport of departure; (ii) The departure time; and (iii) The registration number of the aircraft... contract of conditional sale involving a U.S.-registered large civil aircraft and entered into after...

14 CFR 91.23 - Truth-in-leasing clause requirement in leases and conditional sales contracts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aircraft Registration Branch, Attn: Technical Section, P.O. Box 25724, Oklahoma City, OK 73125; (2) A copy... the airport of departure; (ii) The departure time; and (iii) The registration number of the aircraft... contract of conditional sale involving a U.S.-registered large civil aircraft and entered into after...

77 FR 49035 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-15

...; and (iii) establish a fee of $0.10 per contract for NYSE Amex Options Market Maker executions of SPY... than SPY would continue to pay the existing transaction charges, as provided in the Fee Schedule. 2... for SPY options are currently $0.25 per contract, which, when coupled with the proposed $0.10 per...

Major Current Issues Impacting Government Contracting and Acquisition

DTIC Science & Technology

1984-12-01

22 E . THE OUTLOOK FOR ACQUISITION-----------24 III. COMPETITION IN ACQUISITION--------------30 A. INTRODUCTION--------------------30 B... E . THE EFFECT OF COMPETITION ADVOCACY - - - 50 F. THE COMPETITION IN CONTRACTING ACT OF 1984 ----------------- 53 a. THE FUTURE OF COMPETITION ...plus a reasonable return. Between these two types of market structure, pure competition and monopoly, there exist two other fo, rrs of marketing

Development and Validation of Methods for Applying Pharmacokinetic Data in Risk Assessment. Volume 3. Tetrachloroethylene

DTIC Science & Technology

1990-12-01

Armstrong Aerospace Medical Research Laboratory, Wright Paterson Air Force Base, and Drs. Melvin Andersen and Michael Cargas , formerly with the Harry G...based on the arterial blood concentration surrogate were more III-1-10 similar to those de ’!ved in the traditional manner than were the estimates based on...pharmacokinetic modeling. Prepared by Office of Risk Analysis, Oak Ridge National L-ioratory, Oak Pidge, Tenn.zsee. Prepared under Contract No. DE -ACO5-84

Advanced flight hardware for organic separations using aqueous two-phase partitioning

NASA Astrophysics Data System (ADS)

Deuser, Mark S.; Vellinger, John C.; Weber, John T.

1996-03-01

Separation of cells and cell components is the limiting factor in many biomedical research and pharmaceutical development processes. Aqueous Two-Phase Partitioning (ATPP) is a unique separation technique which allows purification and classification of biological materials. SHOT has employed the ATPP process in separation equipment developed for both space and ground applications. Initial equipment development and research focused on the ORganic SEParation (ORSEP) space flight experiments that were performed on suborbital rockets and the shuttle. ADvanced SEParations (ADSEP) technology was developed as the next generation of ORSEP equipment through a NASA Small Business Innovation Research (SBIR) contract. Under the SBIR contract, a marketing study was conducted, indicating a growing commercial market exists among biotechnology firms for ADSEP equipment and associated flight research and development services. SHOT is preparing to begin manufacturing and marketing laboratory versions of the ADSEP hardware for the ground-based market. In addition, through a self-financed SBIR Phase III effort, SHOT is fabricating and integrating the ADSEP flight hardware for a commercially-driven SPACEHAB 04 experiment that will be the initial step in marketing space separations services. The ADSEP ground-based and microgravity research is expected to play a vital role in developing important new biomedical and pharmaceutical products.

78 FR 30322 - Section 8 Housing Assistance Payments Program-Annual Adjustment Factors, Fiscal Year 2013

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... level will be the new rent to owner. The new rent to owner will not be reduced below the contract rent on the effective date of the HAP contract. III. When to Use Reduced AAFs (From AAF Table 2) In... AAF is reduced by 0.01: For all tenancies assisted in the Section 8 Project-Based Certificate program...

Operation Arctic Heat Case and Exercise for Advanced Contingency Contracting

DTIC Science & Technology

2012-04-30

hOme early fOr repa1rs ~r belno ttilll’lmcd by lii tugi:IOM, !hereby ~no a kw ~raptts In dli! t>aNy ttfaiF. A ~~an C- 130 Svj)et ~Iii::$ m lllt! iry ...and procedures for return of all rental items; (ii) Det ermine which contract s require forma l termination for convenience actions and init iate

Developing a Free-Piston Stirling Convertor for advanced radioisotope space power systems

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Augenblick, John E.; White, Maurice A.; Peterson, Allen A.; Redinger, Darin L.; Petersen, Stephen L.

2002-01-01

The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. This paper provides a description of the Flight Prototype (FP) Stirling convertor design as compared to the previous TDC design. The initial flight prototype units are already undergoing performance tuning at STC. The new design will be hermetically scaled and will provide a weight reduction from approximately 4.8 kg to approximately 3.9 kg. .

Taking the pulse of strategic outsourcing relationships.

PubMed

Getz, Kenneth A; Lamberti, Mary Jo; Kaitin, Kenneth I

2014-10-01

Articles in peer-reviewed journals and the trade press presuppose that strategic outsourcing relationships have been formed to replace preexisting collaborative approaches with contract research organizations. They do not consider that large, fragmented pharmaceutical and biotechnology companies may be supporting competing and conflicting relationship models simultaneously. A recent Tufts Center for the Study of Drug Development study quantifies actual strategic outsourcing practices among drug development companies and sheds new light on why these relationships may be failing. Tufts Center for the Study of Drug Development conducted an in-depth assessment of 43 Phase II and III clinical studies completed since 2012 to examine the outsourcing relationships used by 9 major pharmaceutical and biotechnology companies to support key functional areas. Descriptive statistics were assessed and t tests were performed to characterize outsourcing practices by function and to determine differences in study performance between transactional and strategic outsourcing relationships. The results indicate that sponsor companies are using a variety of outsourcing relationship models to support their studies, mixing and matching the use of internal staff, and using traditional transactional and strategic outsourcing relationships simultaneously. Specifically, despite the fact that each sponsor company had entered into several strategic outsourcing relationships, in no instance did a single contract research organization manage all functional areas supporting an individual Phase II or III study. In addition, sponsor companies vary the types of outsourcing relationship models that they use on a study-by-study basis. The inability of pharmaceutical and biotechnology companies to consistently embrace and coordinate sourcing strategies is creating internal friction and inefficiency. As a result, the expected impact of strategic outsourcing relationships on drug development performance, quality, and cost remains elusive. Copyright © 2014. Published by Elsevier Inc.

[Positive inotropic and lusitropic effect of RP 62719, a new class III antiarrhythmia agent].

PubMed

Beregi, J P; Escande, D; Coudray, N; Chemla, D; Mestre, M; Péry, N; Lecarpentier, Y

1994-02-01

Antiarrhythmic drugs, especially the Class I family, exert a negative inotropic effect on the myocardium which is particularly undesirable in patients with depressed left ventricular function. Therefore, research has been directed to the development of new, more specific molecules of the Class III family. The authors studies the mechanical effects of RP 62719 on guinea pig left ventricular papillary muscle. This new molecule is a pure Class III antiarrhythmic, known to lengthen the duration of the cardiac action potential by selectively blocking the potassium current iK1 (inward rectifier K+ current). The mechanical parameters were determined during the phases of contraction and relaxation under isotonic and isometric conditions. At 0.2 and 2 microM concentrations, RP 62719 improved cardiac contraction under both isotonic and isometric conditions with an increase of about 30% of Vmax (p < 0.001), the maximum unloaded shortening velocity delta 1 (p < 0.001), the peak isometric active force normalized per cross-sectional area [AF/S (p < 0.001)]. At these two concentrations, a positive lusitropic effect (improved relaxation) was demonstrated by an increase in negative peak of derivative per mm2-dF/s and maximum lengthening velocity VR max (p < 0.01). At higher concentrations (20 microM), the inotropic and lusitropic effects were less marked with a bell-shaped form of the dose-effect curve. This study indicates that RP 62719 has moderate but significant positive inotropic and lusitropic effects. These actions could provide significant therapeutic advantages especially in patients cardiac failure.

Redefining the functional roles of the gastrointestinal migrating motor complex and motilin in small bacterial overgrowth and hunger signaling.

PubMed

Deloose, Eveline; Tack, Jan

2016-02-15

During the fasting state the upper gastrointestinal tract exhibits a specific periodic migrating contraction pattern that is known as the migrating motor complex (MMC). Three different phases can be distinguished during the MMC. Phase III of the MMC is the most active of the three and can start either in the stomach or small intestine. Historically this pattern was designated to be the housekeeper of the gut since disturbances in the pattern were associated with small intestinal bacterial overgrowth; however, its role in the involvement of hunger sensations was already hinted in the beginning of the 20th century by both Cannon (Cannon W, Washburn A. Am J Physiol 29: 441-454, 1912) and Carlson (Carlson A. The Control of Hunger in Health and Disease. Chicago, IL: Univ. of Chicago Press, 1916). The discovery of motilin in 1973 shed more light on the control mechanisms of the MMC. Motilin plasma levels fluctuate together with the phases of the MMC and induce phase III contractions with a gastric onset. Recent research suggests that these motilin-induced phase III contractions signal hunger in healthy subjects and that this system is disturbed in morbidly obese patients. This minireview describes the functions of the MMC in the gut and its regulatory role in controlling hunger sensations. Copyright © 2016 the American Physiological Society.

[Contraction (retraction) of blood clots in patients with ischemic stroke].

PubMed

Peshkova, A D; Saikhunov, M V; Demin, T V; Lozhkin, A P; Panasyuk, M V; Litvinov, R I; Khasanova, D R

2016-01-01

To study a possible pathogenetic role of the blood clot contraction and its disturbances in the acute stage of ischemic stroke (IS). Using a new instrumental technique to study the dynamics of clot contraction in vitro, the authors have determined quantitative parameters of clot contraction (the extent and rate of contraction, duration of the lag-period) in the blood of 85 patients with acute IS. The contractile activity of blood clots was substantially reduced compared to the blood of healthy subjects. Correlations between hemostatic and contractile parameters suggest that the reduced clot contraction in stroke is due to the lower platelet count and impaired platelet functionality, higher levels of fibrinogen and antithrombin III as well as higher hematocrit and hemoglobin contents, leukocytosis, and changes in the biochemical blood composition. The results show that the reduced ability of clots may be a novel pathogenic mechanism that aggravates the course and outcomes of IS.

SEAS (Surveillance Environmental Acoustic Support Program) Support

DTIC Science & Technology

1984-02-29

ASEPS software - Provide support for AMES - Support for OUTPOST CREOLE, BIG DIPPER and MFA , First, a summary of the tasks as delineated in the contract...addition, the contractor will provide an engineer/scientist to support the BIG DIPPER data processing activities at NOSC. Task 3: SEAS Inventory - The...SI to provide support to SEAS for the OUTPOST -’ CREOLE III exercise which followed immediately after the BIG DIPPER .. exercise. OUTPOST CREOLE III

Phase 2 Site Investigations Report. Volume 3 of 3: Appendices

DTIC Science & Technology

1994-09-01

Phase II Site Investigations Ee Report Cn Volume III of III Appendices Fort Devens Sudbury Training Annex, Massachusetts September 1994 Contract No...laboratory quality control (QC) samples collected during field investigations at the Sudbury Training Annex of Fort Devens , Massachusetts. The QC...returned to its original condition. E & E performed this procedure for each monitoring well tested during the 1993 slug testing activities at Fort Devens

A Non-Dimensional Analysis of Cardiovascular Response to Cold Stress. Part I. Identification of the Physical Parameters that Govern the Thermoregulatory Function of the Cardiovascular System.

DTIC Science & Technology

1983-09-01

together with an increased ventricular distensibility , tend to raise the end - 66 - diastolic volume. Again, however, :he inadequace emptying tends to... Distensibility (Sympathetic Increase, Para- sympathetic Decrease); (xi) Atrial contraction (end diastolic volume), (enhanced by sympathetic stimulation...Relationships For Striated Skeletal Muscle; Part III, Mechanics and Energetics of Muscular Contraction," Virginia Polytechnic Institute and State

48 CFR 15.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2010 CFR

2010-10-01

... are: I Price Analysis, II Quantitative Techniques for Contract Pricing, III Cost Analysis, IV Advanced... estimates. (vi) Comparison of proposed prices with prices obtained through market research for the same or...

48 CFR 15.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2011 CFR

2011-10-01

... are: I Price Analysis, II Quantitative Techniques for Contract Pricing, III Cost Analysis, IV Advanced... estimates. (vi) Comparison of proposed prices with prices obtained through market research for the same or...

48 CFR 15.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2012 CFR

2012-10-01

... are: I Price Analysis, II Quantitative Techniques for Contract Pricing, III Cost Analysis, IV Advanced... estimates. (vi) Comparison of proposed prices with prices obtained through market research for the same or...

26 CFR 1.860G-2 - Other rules.

Code of Federal Regulations, 2010 CFR

2010-04-01

... certificate or other interest unless the investment trust structure was created to avoid the prohibited... interest and the cap contract as discrete property rights. (iii) The separate existence of the REMIC trust...

7 CFR 1773.39 - Utility plant and accumulated depreciation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... all services contracted for were in fact rendered; (iii) Reviewed time cards and pay rates for several... differences in the workpapers; and (3) Commented, in the management letter, on any discrepancies. (d...

48 CFR 15.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2014 CFR

2014-10-01

... are: I Price Analysis, II Quantitative Techniques for Contract Pricing, III Cost Analysis, IV Advanced... obtained through market research for the same or similar items. (vii) Analysis of data other than certified...

48 CFR 15.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2013 CFR

2013-10-01

... are: I Price Analysis, II Quantitative Techniques for Contract Pricing, III Cost Analysis, IV Advanced... obtained through market research for the same or similar items. (vii) Analysis of data other than certified...

Comparison of the efficiency of rat papillary muscles during afterloaded isotonic contractions and contractions with sinusoidal length changes.

PubMed

Mellors, L J; Gibbs, C L; Barclay, C J

2001-05-01

The results of previous studies suggest that the maximum mechanical efficiency of rat papillary muscles is lower during a contraction protocol involving sinusoidal length changes than during one involving afterloaded isotonic contractions. The aim of this study was to compare directly the efficiency of isolated rat papillary muscle preparations in isotonic and sinusoidal contraction protocols. Experiments were performed in vitro (27 degrees C) using left ventricular papillary muscles from adult rats. Each preparation performed three contraction protocols: (i) low-frequency afterloaded isotonic contractions (10 twitches at 0.2 Hz), (ii) sinusoidal length change contractions with phasic stimulation (40 twitches at 2 Hz) and (iii) high-frequency afterloaded isotonic contractions (40 twitches at 2 Hz). The first two protocols resembled those used in previous studies and the third combined the characteristics of the first two. The parameters for each protocol were adjusted to those that gave maximum efficiency. For the afterloaded isotonic protocols, the afterload was set to 0.3 of the maximum developed force. The sinusoidal length change protocol incorporated a cycle amplitude of +/-5% resting length and a stimulus phase of -10 degrees. Measurements of force output, muscle length change and muscle temperature change were used to calculate the work and heat produced during and after each protocol. Net mechanical efficiency was defined as the proportion of the energy (enthalpy) liberated by the muscle that appeared as work. The efficiency in the low-frequency, isotonic contraction protocol was 21.1+/-1.4% (mean +/- s.e.m., N=6) and that in the sinusoidal protocol was 13.2+/-0.7%, consistent with previous results. This difference was not due to the higher frequency or greater number of twitches because efficiency in the high-frequency, isotonic protocol was 21.5+/-1.0%. Although these results apparently confirm that efficiency is protocol-dependent, additional experiments designed to measure work output unambiguously indicated that the method used to calculate work output in isotonic contractions overestimated actual work output. When net work output, which excludes work done by parallel elastic elements, rather than total work output was used to determine efficiency in afterloaded isotonic contractions, efficiency was similar to that for sinusoidal contractions. The maximum net mechanical efficiency of rat papillary muscles performing afterloaded isotonic or sinusoidal length change contractions was between 10 and 15%.

How Can We Best Achieve Contracting Unity of Effort in the CENTCOM Area of Responsibility?

DTIC Science & Technology

2013-11-20

Major Torres’ military decorations include the Bronze Star Medal, the Army Meritorious Medal with oak leaf (OLC), the Army Commendation Medal...1990–May 1991). Major Ross’ military decorations include the Bronze Star Medal, the Army Meritorious Medal with two oak leaf (OLC), the Army...Berteau, D. J., Maddox, D. M., Oliver , D. R., Jr., Salomon, L. E., & Singley, G. T., III. (2007). Urgent reform required: Army expeditionary contracting

The LOGCAP III to LOGCAP IV Transition in Northern Afghanistan. Contract Services Phase-in and Phase-out on a Grand Scale

DTIC Science & Technology

2011-02-01

Contracting • Engineering and Technology • Logistics • Acquisition Management • Program Management For more information , visit http://clc.dau.mil ...for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data...sources, gathering and maintaining the data needed, and completing and reviewing the collection of information . Send comments regarding this burden

Compliance program data management system for The Idaho National Engineering Laboratory/Environmental Protection Agency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hertzler, C.L.; Poloski, J.P.; Bates, R.A.

1988-01-01

The Compliance Program Data Management System (DMS) developed at the Idaho National Engineering Laboratory (INEL) validates and maintains the integrity of data collected to support the Consent Order and Compliance Agreement (COCA) between the INEL and the Environmental Protection Agency (EPA). The system uses dBase III Plus programs and dBase III Plus in an interactive mode to enter, store, validate, manage, and retrieve analytical information provided on EPA Contract Laboratory Program (CLP) forms and CLP forms modified to accommodate 40 CFR 264 Appendix IX constituent analyses. Data analysis and presentation is performed utilizing SAS, a statistical analysis software program. Archivingmore » of data and results is performed at appropriate stages of data management. The DMS is useful for sampling and analysis programs where adherence to EPA CLP protocol, along with maintenance and retrieval of waste site investigation sampling results is desired or requested. 3 refs.« less

The Utilization of the Microflora Indigenous to and Present in Oil-Bearing Formations to Selectively Plug the More Porous Zones Thereby Increasing Oil Recovery During Waterflooding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Lewis R.; Byrnes, Martin J.; Stephens, James O.

This project was designed to demonstrate that a microbially enhanced oil recovery process (MEOR), developed in part under DOE Contract No. DE-AC22-90BC14665, will increase oil recovery from fluvial dominated deltaic oil reservoirs. The process involves stimulating the in-situ indigenous microbial population in the reservoir to grow in the more permeable zones, thus diverting flow to other areas of the reservoir, thereby increasing the effectiveness of the waterflood. This five and a half year project is divided into three phases, Phase I, Planning and Analysis (9 months), Phase II, Implementation (45 months), and Phase III, Technology Transfer (12 months). Phase Imore » was completed and reported in the first annual report. This fifth annual report covers the completion of Phase II and the first six months of Phase III.« less

48 CFR 252.228-7003 - Capture and detention.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with the United States in a common military effort; or (iii) Known to have been taken prisoner, hostage... detention shall not be considered as time spent in contract performance, and the Government shall not be...

48 CFR 252.228-7003 - Capture and detention.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with the United States in a common military effort; or (iii) Known to have been taken prisoner, hostage... detention shall not be considered as time spent in contract performance, and the Government shall not be...

48 CFR 252.228-7003 - Capture and detention.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with the United States in a common military effort; or (iii) Known to have been taken prisoner, hostage... detention shall not be considered as time spent in contract performance, and the Government shall not be...

48 CFR 252.228-7003 - Capture and detention.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with the United States in a common military effort; or (iii) Known to have been taken prisoner, hostage... detention shall not be considered as time spent in contract performance, and the Government shall not be...

48 CFR 252.228-7003 - Capture and detention.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with the United States in a common military effort; or (iii) Known to have been taken prisoner, hostage... detention shall not be considered as time spent in contract performance, and the Government shall not be...

48 CFR 32.101 - Authority.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.101 Authority. The basic authority... Procurement Act (10 U.S.C. 2307), and Title III of the Defense Production Act of 1950 (50 U.S.C. App. 2091...

48 CFR 32.101 - Authority.

Code of Federal Regulations, 2011 CFR

2011-10-01

... REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.101 Authority. The basic authority... Procurement Act (10 U.S.C. 2307), and Title III of the Defense Production Act of 1950 (50 U.S.C. App. 2091...

23 CFR 636.204 - What items may be included in a phase-one solicitation?

Code of Federal Regulations, 2013 CFR

2013-04-01

... ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.204... perform (including key personnel); and (iii) Past performance of the members of the offeror's team...

23 CFR 636.204 - What items may be included in a phase-one solicitation?

Code of Federal Regulations, 2012 CFR

2012-04-01

... ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.204... perform (including key personnel); and (iii) Past performance of the members of the offeror's team...

23 CFR 636.204 - What items may be included in a phase-one solicitation?

Code of Federal Regulations, 2010 CFR

2010-04-01

... ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.204... perform (including key personnel); and (iii) Past performance of the members of the offeror's team...

23 CFR 636.204 - What items may be included in a phase-one solicitation?

Code of Federal Regulations, 2014 CFR

2014-04-01

... ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.204... perform (including key personnel); and (iii) Past performance of the members of the offeror's team...

23 CFR 636.204 - What items may be included in a phase-one solicitation?

Code of Federal Regulations, 2011 CFR

2011-04-01

... ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.204... perform (including key personnel); and (iii) Past performance of the members of the offeror's team...

26 CFR 1.860G-2 - Other rules.

Code of Federal Regulations, 2013 CFR

2013-04-01

... investment trust structure was created to avoid the prohibited transaction rules of section 860F(a). (7) Test... interest and the cap contract as discrete property rights. (iii) The separate existence of the REMIC trust...

26 CFR 1.860G-2 - Other rules.

Code of Federal Regulations, 2011 CFR

2011-04-01

... investment trust structure was created to avoid the prohibited transaction rules of section 860F(a). (7) Test... interest and the cap contract as discrete property rights. (iii) The separate existence of the REMIC trust...

26 CFR 1.860G-2 - Other rules.

Code of Federal Regulations, 2012 CFR

2012-04-01

... investment trust structure was created to avoid the prohibited transaction rules of section 860F(a). (7) Test... interest and the cap contract as discrete property rights. (iii) The separate existence of the REMIC trust...

Fatigue-related firing of muscle nociceptors reduces voluntary activation of ipsilateral but not contralateral lower limb muscles.

PubMed

Kennedy, David S; Fitzpatrick, Siobhan C; Gandevia, Simon C; Taylor, Janet L

2015-02-15

During fatiguing upper limb exercise, maintained firing of group III/IV muscle afferents can limit voluntary drive to muscles within the same limb. It is not known if this effect occurs in the lower limb. We investigated the effects of group III/IV muscle afferent firing from fatigued ipsilateral and contralateral extensor muscles and ipsilateral flexor muscles of the knee on voluntary activation of the knee extensors. In three experiments, we examined voluntary activation of the knee extensors by measuring changes in superimposed twitches evoked by femoral nerve stimulation. Subjects attended on 2 days for each experiment. On one day a sphygmomanometer cuff occluded blood flow of the fatigued muscles to maintain firing of group III/IV muscle afferents. After a 2-min extensor contraction (experiment 1; n = 9), mean voluntary activation was lower with than without maintained ischemia (47 ± 19% vs. 87 ± 8%, respectively; P < 0.001). After a 2-min knee flexor maximal voluntary contraction (MVC) (experiment 2; n = 8), mean voluntary activation was also lower with than without ischemia (59 ± 21% vs. 79 ± 9%; P < 0.01). After the contralateral (left) MVC (experiment 3; n = 8), mean voluntary activation of the right leg was similar with or without ischemia (92 ± 6% vs. 93 ± 4%; P = 0.65). After fatiguing exercise, activity in group III/IV muscle afferents reduces voluntary activation of the fatigued muscle and nonfatigued antagonist muscles in the same leg. However, group III/IV muscle afferents from the fatigued left leg had no effect on the unfatigued right leg. This suggests that any "crossover" of central fatigue in the lower limbs is not mediated by group III/IV muscle afferents. Copyright © 2015 the American Physiological Society.

A series of Ln-p-chlorobenzoic acid–terpyridine complexes: lanthanide contraction effects, supramolecular interactions and luminescent behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carter, Korey P.; Pope, Simon J. A.; Cahill, Christopher L.

Fifteen new lanthanide p-chlorobenzoic acid complexes, [PrL3(terpy)(H2O)]2 (1), [LnL3(terpy)(H2O)]2 (Ln = Nd (2), Sm (3), and Eu (4)), and [LnL3(terpy)(H2O)] (Ln = Sm (3'), Eu (4'), Gd (5), Tb (6), Dy (7), Ho (8), Er (9), Tm (10), Yb (11), Lu (12), and Y (13); HL: p-chlorobenzoic acid; terpy: 2,2':6',2''-terpyridine), have been synthesized hydrothermally at varying temperatures and structurally characterized by single crystal and powder X-ray diffraction. The series is comprised of binuclear molecular units (Pr–Eu) that give way to mononuclear molecular complexes (Sm–Y) as the lanthanide contraction takes effect. All fifteen complexes feature a tridentate terpyridine ligand, p-chlorobenzoic acidmore » ligands exhibiting multiple binding modes, bidentate, bridging bidentate, and monodentate, and a bound water molecule. Binuclear complexes 1–4 are stitched together via intermolecular interactions: aromatic–aromatic interactions for 1, halogen•••halogen interactions for 2–4, to form 1D chains. Mononuclear complexes 3', 4', and 5–13 utilize supramolecular hydrogen and halogen bonding to form 2D sheets. Visible and near-IR solid state luminescence studies were performed on complexes 2, 3, 3', 4, 4', 6, 7 and 11 and the characteristic visible luminescence of Sm(III), Eu(III), Tb(III), and Dy(III) was exhibited. The near-IR spectra of the Nd(III) and Yb(III) complexes exhibit weak characteristic luminescence, showing that terpy can act as a sensitizing chromophore in these systems.« less

Burn wound healing property of Cocos nucifera: An appraisal

PubMed Central

Srivastava, Pallavi; Durgaprasad, S.

2008-01-01

Objectives: The study was undertaken to evaluate the burn wound healing property of oil of Cocos nucifera and to compare the effect of the combination of oil of Cocos nucifera and silver sulphadiazine with silver sulphadiazine alone. Materials and Methods: Partial thickness burn wounds were inflicted upon four groups of six rats each. Group I was assigned as control, Group II received the standard silver sulphadiazine. Group III was given pure oil of Cocos nucifera , and Group IV received the combination of the oil and the standard. The parameters observed were epithelialization period and percentage of wound contraction. Results: It was noted that there was significant improvement in burn wound contraction in the group treated with the combination of Cocos nucifera and silver sulphadiazine. The period of epithelialization also decreased significantly in groups III and IV. Conclusion: It is concluded that oil of Cocos nucifera is an effective burn wound healing agent. PMID:20040946

Effects of aluminum hinged shoes on the structure of contracted feet in Thoroughbred yearlings.

PubMed

Tanaka, Kousuke; Hiraga, Atsushi; Takahashi, Toshiyuki; Kuwano, Atsutoshi; Morrison, Scott Edward

2015-01-01

We applied aluminum hinged shoes (AHSs) to the club foot-associated contracted feet of 11 Thoroughbred yearlings to examine the effects of the shoes on the shape of the hoof and third phalanx (P III). After 3 months of AHS use, the size of the affected hooves increased significantly, reaching the approximate size of the healthy contralateral hooves with respect to the maximum lateral width of the foot, the mean ratio of the bearing border width to the coronary band width, and the mean ratio of the solar surface width to the articular surface width. These results suggest that the AHSs corrected the contracted feet in these yearling horses.

34 CFR 5.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., and retrievable in electronic format; (ii) Records maintained for the Department by a private entity under a records management contract with the Federal Government; and (iii) Documentary materials... documents preserved only for convenience of reference; stocks of publications; and personal records created...

34 CFR 5.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., and retrievable in electronic format; (ii) Records maintained for the Department by a private entity under a records management contract with the Federal Government; and (iii) Documentary materials... documents preserved only for convenience of reference; stocks of publications; and personal records created...

34 CFR 5.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., and retrievable in electronic format; (ii) Records maintained for the Department by a private entity under a records management contract with the Federal Government; and (iii) Documentary materials... documents preserved only for convenience of reference; stocks of publications; and personal records created...

7 CFR 760.403 - Eligible owners and contract growers.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., the applicant must have had legal ownership of the eligible livestock on the day the livestock died... eligible livestock on the day the livestock died; and (iii) A risk of loss in the animal. (b) A producer...

The challenge of contracting for technological information.

PubMed

Zeckhauser, R

1996-11-12

Contracting to provide technological information (TI) is a significant challenge. TI is an unusual commodity in five ways. (i) TI is difficult to count and value; conventional indicators, such as patients and citations, hardly indicate value. TI is often sold at different prices to different parties. (ii) To value TI, it may be necessary to "give away the secret." This danger, despite nondisclosure agreements, inhibits efforts to market TI. (iii) To prove its value, TI is often bundled into complete products, such as a computer chip or pharmaceutical product. Efficient exchange, by contrast, would involve merely the raw information. (iv) Sellers' superior knowledge about TI's value make buyers wary of overpaying. (v) Inefficient contracts are often designed to secure rents from TI. For example, licensing agreements charge more than marginal cost. These contracting difficulties affect the way TI is produced, encouraging self-reliance. This should be an advantage to large firms. However, small research and development firms spend more per employee than large firms, and nonprofit universities are major producers. Networks of organizational relationships, particularly between universities and industry, are critical in transmitting TI. Implicit barter-money for guidance-is common. Property rights for TI are hard to establish. Patents, quite suitable for better mousetraps, are inadequate for an era when we design better mice. Much TI is not patented, and what is patented sets fuzzy demarcations. New organizational forms are a promising approach to contracting difficulties for TI. Webs of relationships, formal and informal, involving universities, start-up firms, corporate giants, and venture capitalists play a major role in facilitating the production and spread of TI.

The challenge of contracting for technological information

PubMed Central

Zeckhauser, Richard

1996-01-01

Contracting to provide technological information (TI) is a significant challenge. TI is an unusual commodity in five ways. (i) TI is difficult to count and value; conventional indicators, such as patents and citations, hardly indicate value. TI is often sold at different prices to different parties. (ii) To value TI, it may be necessary to “give away the secret.” This danger, despite nondisclosure agreements, inhibits efforts to market TI. (iii) To prove its value, TI is often bundled into complete products, such as a computer chip or pharmaceutical product. Efficient exchange, by contrast, would involve merely the raw information. (iv) Sellers’ superior knowledge about TI’s value make buyers wary of overpaying. (v) Inefficient contracts are often designed to secure rents from TI. For example, licensing agreements charge more than marginal cost. These contracting difficulties affect the way TI is produced, encouraging self-reliance. This should be an advantage to large firms. However, small research and development firms spend more per employee than large firms, and nonprofit universities are major producers. Networks of organizational relationships, particularly between universities and industry, are critical in transmitting TI. Implicit barter—money for guidance—is common. Property rights for TI are hard to establish. Patents, quite suitable for better mousetraps, are inadequate for an era when we design better mice. Much TI is not patented, and what is patented sets fuzzy demarcations. New organizational forms are a promising approach to contracting difficulties for TI. Webs of relationships, formal and informal, involving universities, start-up firms, corporate giants, and venture capitalists play a major role in facilitating the production and spread of TI. PMID:8917488

Surgery-first: a new approach to orthognathic surgery

PubMed Central

DE NUCCIO, F.; DE NUCCIO, F.; D’EMIDIO, M.M.; PELO, S.

2016-01-01

SUMMARY This case study describes the treatment of a 20-year-old white woman with a skeletal Class III and dental Class III malocclusion followed by a retrognathic and contracted maxilla, light mandibular crowding and a median line deviation of 5 mm. The treatment was based on the Surgery-First approach, involving LeFort I maxillary advancement surgery, and it was followed by orthodontic treatment. During the 6-month treatment period, excellent aesthetic results and good functional occlusion were achieved. PMID:28280538

Dynamic aspects of the contractile system in Physarum plasmodium. III. Cyclic contraction-relaxation of the plasmodial fragment in accordance with the generation-degeneration of cytoplasmic actomyosin fibrils

PubMed Central

1987-01-01

Plasmodial fragments of Physarum polycephalum, excised from anterior regions of a thin-spread plasmodium, contracted-relaxed cyclicly with a period of 3-5 min. The area of the fragments decreased approximately 10% during contraction. In most cases, there was little endoplasmic streaming which indicates that contractions were synchronized throughout the fragment. By both polarized light and fluorescence microscopy, the organization and distribution of the cytoplasmic actomyosin fibrils in the fragments changed in synchrony with the contraction cycle. The fibrils formed during the contraction phase, and finally became a highly organized framework consisting of a three- dimensional network of numerous fibrils with many converging points (the nodes). During relaxation, the fibrils degenerated and disappeared almost completely, though some very weak fibrils remained near the nodes and the periphery. The results obtained by fluorometry of the fragments, stained with rhodamine-phalloidin, suggested that the G-F transformation of actin is not the main underlying process of the fibrillar formation. PMID:3611192

Electrically evoked local muscle contractions cause an increase in hippocampal BDNF.

PubMed

Maekawa, Takahiro; Ogasawara, Riki; Tsutaki, Arata; Lee, Kihyuk; Nakada, Satoshi; Nakazato, Koichi; Ishii, Naokata

2018-05-01

High-intensity exercise has recently been shown to cause an increase in brain-derived neurotropic factor (BDNF) in the hippocampus. Some studies have suggested that myokines secreted from contracting skeletal muscle, such as irisin (one of the truncated form of fibronectin type III domain-containing protein 5 (FNDC5)), play important roles in this process. Thus, we hypothesized that locally evoked muscle contractions may cause an increase of BDNF in the hippocampus through some afferent mechanisms. Under anesthesia, Sprague-Dawley rats were fixed on a custom-made dynamometer and their triceps surae muscles were made to maximally contract via delivery of electric stimulations of the sciatic nerve (100 Hz with 1-ms pulse and 3-s duration). Following 50 repeated maximal isometric contractions, the protein expressions of BDNF and activation of its receptor in the hippocampus significantly increased compared with the sham-operated control rats. However, the expression of both BDNF and FNDC5 within stimulated muscles did not significantly increase, nor did their serum concentrations change. These results indicate that local muscular contractions under unconsciousness can induce BDNF expression in the hippocampus. This effect may be mediated by peripheral reception of muscle contraction, but not by systemic factors.

48 CFR 230.201-5 - Waiver.

Code of Federal Regulations, 2010 CFR

2010-10-01

... be fair and reasonable without the application of the Cost Accounting Standards; and (iii) There are... DEFENSE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements... Acquisition Policy, Office of the Under Secretary of Defense (Acquisition, Technology, and Logistics)— (1) May...

29 CFR 34.33 - Methods of Administration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... training plans, contracts, assurances, and other similar agreements; (iii) Procedures for ensuring that... OF THE JOB TRAINING PARTNERSHIP ACT OF 1982, AS AMENDED (JTPA) Governor's Responsibilities To... training to ensure that members of the recipients' staffs who have been assigned responsibilities pursuant...

24 CFR Appendix II to Subpart B of... - Homebuyers Ownership Opportunity Agreement (Turnkey III)

Code of Federal Regulations, 2012 CFR

2012-04-01

... Authority's own staff and resources, existing community resources, a private agency under contract with the... shall be free to act without the HBA action required by this Agreement. 2 There may be cases, such as...

24 CFR Appendix II to Subpart B of... - Homebuyers Ownership Opportunity Agreement (Turnkey III)

Code of Federal Regulations, 2013 CFR

2013-04-01

... Authority's own staff and resources, existing community resources, a private agency under contract with the... shall be free to act without the HBA action required by this Agreement. 2 There may be cases, such as...

24 CFR Appendix II to Subpart B of... - Homebuyers Ownership Opportunity Agreement (Turnkey III)

Code of Federal Regulations, 2014 CFR

2014-04-01

... Authority's own staff and resources, existing community resources, a private agency under contract with the... shall be free to act without the HBA action required by this Agreement. 2 There may be cases, such as...

48 CFR 1352.216-71 - Level of effort (cost-plus-fixed-fee, term contract).

Code of Federal Regulations, 2010 CFR

2010-10-01

... Optionperiod II Optionperiod III xxxxxxxxxx xxxx xxxx xxxx xxxx xxxxxxxxxx xxxx xxxx xxxx xxxx Total Direct Labor xxxx xxxx xxxx xxxx (c) The hours specified above are provided as estimates only. If the actual...

Contracting out to improve the use of clinical health services and health outcomes in low- and middle-income countries.

PubMed

Odendaal, Willem A; Ward, Kim; Uneke, Jesse; Uro-Chukwu, Henry; Chitama, Dereck; Balakrishna, Yusentha; Kredo, Tamara

2018-04-03

Contracting out of governmental health services is a financing strategy that governs the way in which public sector funds are used to have services delivered by non-governmental health service providers (NGPs). It represents a contract between the government and an NGP, detailing the mechanisms and conditions by which the latter should provide health care on behalf of the government. Contracting out is intended to improve the delivery and use of healthcare services. This Review updates a Cochrane Review first published in 2009. To assess effects of contracting out governmental clinical health services to non-governmental service provider/s, on (i) utilisation of clinical health services; (ii) improvement in population health outcomes; (iii) improvement in equity of utilisation of these services; (iv) costs and cost-effectiveness of delivering the services; and (v) improvement in health systems performance. We searched CENTRAL, MEDLINE, Embase, NHS Economic Evaluation Database, EconLit, ProQuest, and Global Health on 07 April 2017, along with two trials registers - ClinicalTrials.gov and the International Clinical Trials Registry Platform - on 17 November 2017. Individually randomised and cluster-randomised trials, controlled before-after studies, interrupted time series, and repeated measures studies, comparing government-delivered clinical health services versus those contracted out to NGPs, or comparing different models of non-governmental-delivered clinical health services. Two authors independently screened all records, extracted data from the included studies and assessed the risk of bias. We calculated the net effect for all outcomes. A positive value favours the intervention whilst a negative value favours the control. Effect estimates are presented with 95% confidence intervals. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the certainty of the evidence and we prepared a Summary of Findings table. We included two studies, a cluster-randomised trial conducted in Cambodia, and a controlled before-after study conducted in Guatemala. Both studies reported that contracting out over 12 months probably makes little or no difference in (i) immunisation uptake of children 12 to 24 months old (moderate-certainty evidence), (ii) the number of women who had more than two antenatal care visits (moderate-certainty evidence), and (iii) female use of contraceptives (moderate-certainty evidence).The Cambodia trial reported that contracting out may make little or no difference in the mortality over 12 months of children younger than one year of age (net effect = -4.3%, intervention effect P = 0.36, clustered standard error (SE) = 3.0%; low-certainty evidence), nor to the incidence of childhood diarrhoea (net effect = -16.2%, intervention effect P = 0.07, clustered SE = 19.0%; low-certainty evidence). The Cambodia study found that contracting out probably reduces individual out-of-pocket spending over 12 months on curative care (net effect = $ -19.25 (2003 USD), intervention effect P = 0.01, clustered SE = $ 5.12; moderate-certainty evidence). The included studies did not report equity in the use of clinical health services and in adverse effects. This update confirms the findings of the original review. Contracting out probably reduces individual out-of-pocket spending on curative care (moderate-certainty evidence), but probably makes little or no difference in other health utilisation or service delivery outcomes (moderate- to low-certainty evidence). Therefore, contracting out programmes may be no better or worse than government-provided services, although additional rigorously designed studies may change this result. The literature provides many examples of contracting out programmes, which implies that this is a feasible response when governments fail to provide good clinical health care. Future contracting out programmes should be framed within a rigorous study design to allow valid and reliable measures of their effects. Such studies should include qualitative research that assesses the views of programme implementers and beneficiaries, and records implementation mechanisms. This approach may reveal enablers for, and barriers to, successful implementation of such programmes.

75 FR 63207 - Notice of Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-14

... INFORMATION: I. Abstract This information collection helps to ensure that engineering changes to contracts are... which are used for proposal preparation. NASA encourages the use of computer technology for preparing proposals and submission. III. Data Title: Modifications Related to Engineering Change Proposals. OMB Number...

75 FR 77006 - Notice of Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

... INFORMATION: I. Abstract This information collection helps to ensure that engineering changes to contracts are... proposal preparation. NASA encourages the use of computer technology for preparing proposals and submission. III. Data Title: Modifications Related to Engineering Change Proposals. OMB Number: 2700-0054. Type of...

Tracking state deployments of commercial vehicle information systems and networks : 1998 Washington State report

DOT National Transportation Integrated Search

1999-12-01

Volume III of the Logical Architecture contract deliverable documents the Data Dictionary. This formatted version of the Teamwork model data dictionary is mechanically produced from the Teamwork CDIF (Case Data Interchange Format) output file. It is ...

77 FR 75200 - New International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... person identified in the FOR FURTHER INFORMATION CONTACT section by telephone for advice on filing alternatives. FOR FURTHER INFORMATION CONTACT: Stephen L. Sharfman, General Counsel, at 202-789-6820. SUPPLEMENTARY INFORMATION: Table of Contents I. Introduction II. Contents of Filing III. Commission Action IV...

77 FR 75452 - New International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-20

... person identified in the FOR FURTHER INFORMATION CONTACT section by telephone for advice on filing alternatives. FOR FURTHER INFORMATION CONTACT: Stephen L. Sharfman, General Counsel, at 202-789-6820. SUPPLEMENTARY INFORMATION: Table of Contents I. Introduction II. Contents of Filing III. Commission Action IV...

48 CFR 1352.209-71 - Limitation of future contracting.

Code of Federal Regulations, 2010 CFR

2010-10-01

... towards solution of broadly defined problems. This may encompass research, evaluating technical feasibility, proof of design and test, or engineering of programs not yet approved for acquisition or operation. (iii) “Proprietary Information” means all information designated as proprietary in accordance...

48 CFR 1352.209-71 - Limitation of future contracting.

Code of Federal Regulations, 2011 CFR

2011-10-01

... towards solution of broadly defined problems. This may encompass research, evaluating technical feasibility, proof of design and test, or engineering of programs not yet approved for acquisition or operation. (iii) “Proprietary Information” means all information designated as proprietary in accordance...

48 CFR 52.215-11 - Price Reduction for Defective Certified Cost or Pricing Data-Modifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... affirmative action to bring the character of the data to the attention of the Contracting Officer. (iii) The... price reduction, the Contractor shall be liable to and shall pay the United States at the time such...

48 CFR 52.215-11 - Price Reduction for Defective Certified Cost or Pricing Data-Modifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... affirmative action to bring the character of the data to the attention of the Contracting Officer. (iii) The... price reduction, the Contractor shall be liable to and shall pay the United States at the time such...

48 CFR 52.215-11 - Price Reduction for Defective Certified Cost or Pricing Data-Modifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... affirmative action to bring the character of the data to the attention of the Contracting Officer. (iii) The... price reduction, the Contractor shall be liable to and shall pay the United States at the time such...

14 CFR 119.36 - Additional certificate application requirements for commercial operators.

Code of Federal Regulations, 2010 CFR

2010-01-01

... existing and anticipated income producing contracts and estimated revenue per mile or hour of operation by... debt (explain); (iii) Additional working capital (explain); (iv) Operating losses other than... (explain); (iv) Working capital reduction (explain); (v) Operations (profits) (explain); (vi) Depreciation...

48 CFR 230.201-5 - Waiver.

Code of Federal Regulations, 2011 CFR

2011-10-01

... DEFENSE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements... be fair and reasonable without the application of the Cost Accounting Standards; and (iii) There are... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Waiver. 230.201-5 Section...

AIDS: just the facts from specialists at Johns Hopkins.

PubMed

Finkbeiner, A

1985-12-01

This article, based on information from specialists at Johns Hopkins, poses and then answers 3 broad questions about the acquired immunodeficiency syndrome (AIDS). 1st, it is asked, "What is AIDS and how serious is it?" It is noted that AIDS is only 1 of several forms taken by infection with the human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). The earliest form of infection is believed to occur within a few weeks of exposure to the virus, and some patients develop an acute syndrome that resembles infectious mononucleosis. These symptoms disappear after 4-6 weeks, by which time the patient has developed antibodies to the virus. About 2-4%/year of asymptomatic carriers go on to develop AIDS-related complex (ARC), and 15-30% of ARC patients develop AIDS within 5 years. The 2nd question posed is, "How do you catch AIDS?" To cause infection, the virus must go directly into the blood, although the virus alone may not be enough to cause sickness. Previous viral infections such as hepatitis B, herpes, cytomegalovirus, and intestinal parasites have been suggested as co-factors of AIDS. Promiscuity increases the chances of contracting AIDS. Observations of the families of AIDS patients and health care personnel who work with AIDS patients suggest that AIDS cannot be caught by casual contact. Finally, it is asked, "What is being done about AIDS?" 4 strategies are outlined: 1) as a result of donor screening for antibodies to HTLV-III/LAV, AIDS has been completely removed from the blood banks; 2) virologists are attempting to understand the virus so that it can be attacked, and understanding has been advanced by the theory that HTLV-III might be what is called a "slow virus;" 3) education about AIDS is changing the sexual practices that transmit AIDS; and 4) epidemiologists are carefully following those who are at risk, have been exposed, or are already sick.

Effect of lanthanide contraction on the mixed polyamine systems Ln/Sb/Se/(en+dien) and Ln/Sb/Se/(en+trien): Syntheses and characterizations of lanthanide complexes with a tetraelenidoantimonate ligand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao Jing; Liang Jingjing; Pan Yingli

Mixed polyamine systems Ln/Sb/Se/(en+dien) and Ln/Sb/Se/(en+trien) (Ln=lanthanide, en=ethylenediamine, dien=diethylenetriamine, trien=triethylenetetramine) were investigated under solvothermal conditions, and novel mixed-coordinated lanthanide(III) complexes [Ln(en){sub 2}(dien)({eta}{sup 2}-SbSe{sub 4})] (Ln=Ce(1a), Nd(1b)), [Ln(en){sub 2}(dien)(SbSe{sub 4})] (Ln=Sm(2a), Gd(2b), Dy(2c)), [Ln(en)(trien)({mu}-{eta}{sup 1},{eta}{sup 2}-SbSe{sub 4})]{sub {infinity}} (Ln=Ce(3a), Nd(3b)) and [Sm(en)(trien)({eta}{sup 2}-SbSe{sub 4})] (4a) were prepared. Two structural types of lanthanide selenidoantimonates were obtained across the lanthanide series in both en+dien and en+trien systems. The tetrahedral anion [SbSe{sub 4}]{sup 3-} acts as a monodentate ligand mono-SbSe{sub 4}, a bidentate chelating ligand {eta}{sup 2}-SbSe{sub 4} or a tridentate bridging ligand {mu}-{eta}{sup 1},{eta}{sup 2}-SbSe{sub 4} to the lanthanide(III) center depending on themore » Ln{sup 3+} ions and the mixed ethylene polyamines, indicating the effect of lanthanide contraction on the structures of the lanthanide(III) selenidoantimonates. The lanthanide selenidoantimonates exhibit semiconducting properties with E{sub g} between 2.08 and 2.51 eV. - Graphical Abstract: Two structural types of lanthanide(III) selenidoantimonates are formed in both en-dien and en-trien mixed polyamines across lanthanide series, indicating the lanthanide contraction effect on the structures of the lanthanide(III) selenidoantimonates. Highlights: > Two structural types of lanthanide selenidoantimonates are prepared across the lanthanide series in both Ln/Sb/Se/(en+dien) and Ln/Sb/Se/(en+trien) systems. > The [SbSe{sub 4}]{sup 3-} anion acts as a mono-SbSe{sub 4}, a {eta}{sup 2}-SbSe{sub 4} or a {mu}-{eta}{sup 1},{eta}{sup 2}-SbSe{sub 4} ligand to the Ln{sup 3+} ions. > The soft base ligand [SbSe{sub 4}]{sup 3-} can be controlled to coordinate to the Ln{sup 3+} ions with en+dien and en+trien as co-ligands.« less

48 CFR 42.803 - Disallowing costs after incurrence.

Code of Federal Regulations, 2010 CFR

2010-10-01

... officers receive vouchers directly from the contractor and, with or without auditor assistance, approve or... agency. (b) Auditor receipt of vouchers. (1) When authorized by agency regulations, the contract auditor... payment those vouchers found acceptable, and (iii) suspend payment of questionable costs. The auditor...

24 CFR 266.630 - Partial payment of claims.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Contract... other resources available to the project are sufficient to restore the financial viability of the project; (iii) The project is or can (at reasonable cost) be made structurally sound; (iv) The management...

48 CFR 42.803 - Disallowing costs after incurrence.

Code of Federal Regulations, 2011 CFR

2011-10-01

... officers receive vouchers directly from the contractor and, with or without auditor assistance, approve or... agency. (b) Auditor receipt of vouchers. (1) When authorized by agency regulations, the contract auditor... payment those vouchers found acceptable, and (iii) suspend payment of questionable costs. The auditor...

77 FR 26175 - Section 42 Qualified Contract Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-03

... fees, operating deficit contributions, and legal, syndication, and accounting costs all are examples of... adjusted investor equity in the building, plus (III) other capital contributions not reflected in these... contributions, not including amounts described in (a) and (b); minus (d) cash distributions from (or available...

7 CFR 1410.33 - Contract modifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... production practices that have a site specific application that would: (i) Meet human needs for food and fiber; (ii) Enhance the environment and the natural resource base; (iii) Use nonrenewable resources... returning some or all of the land into production using sustainable grazing or crop production methods...

7 CFR 1410.33 - Contract modifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... production practices that have a site specific application that would: (i) Meet human needs for food and fiber; (ii) Enhance the environment and the natural resource base; (iii) Use nonrenewable resources... returning some or all of the land into production using sustainable grazing or crop production methods...

7 CFR 1410.33 - Contract modifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... production practices that have a site specific application that would: (i) Meet human needs for food and fiber; (ii) Enhance the environment and the natural resource base; (iii) Use nonrenewable resources... returning some or all of the land into production using sustainable grazing or crop production methods...

7 CFR 1410.33 - Contract modifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... production practices that have a site specific application that would: (i) Meet human needs for food and fiber; (ii) Enhance the environment and the natural resource base; (iii) Use nonrenewable resources... returning some or all of the land into production using sustainable grazing or crop production methods...

Bit Synchronization with Cross Spectrum Synchronization Loop. Attachment III.

DTIC Science & Technology

1981-10-01

AO-AII 1 ICMCR AAE~C BIT SYNCHRONIZATION WITH CROSS SPECTRUM SYNCHRONIZATION LOOP .A_ ETC(U) O’ASFE CT A1 R A MA A 6. A C LINDSEY, C M CHIE NOOOI𔃾...BUR[AU OF STANOARDS 196.- A I~I -I I I Yinwoa on. IAoalt [ S0Box0 2793D, Pasadena Calif 91105 82 03 09098 I7- ATTACHMENT III BIT SYNCHRONIZATION WITH...CROSS SPECTRUM SYNCHRONIZATION LOOP I ’I PREPARED FOR NAVAL RESEARCH LABORATORY WASHINGTON, D.C. 20375 .Jr TECHNICAL MONITOR: MR. MORT FRANK I CONTRACT

75 FR 53127 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-45; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... urban consumers, except for Davis-Bacon Act, Service Contract Act, and trade agreements thresholds. The... Chambers. Cost or Pricing Data. III American Recovery 2009-008 Davis. and Reinvestment Act of 2009 (the Recovery Act)-- Buy American Requirements for Construction Materials. SUPPLEMENTARY INFORMATION: Summaries...

50 CFR 3.3 - Discrimination by contractors and permittees prohibited.

Code of Federal Regulations, 2013 CFR

2013-10-01

... permittees prohibited. 3.3 Section 3.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.3 Discrimination by contractors and permittees prohibited. The provisions of part III of Executive...

50 CFR 3.3 - Discrimination by contractors and permittees prohibited.

Code of Federal Regulations, 2014 CFR

2014-10-01

... permittees prohibited. 3.3 Section 3.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.3 Discrimination by contractors and permittees prohibited. The provisions of part III of Executive...

50 CFR 3.3 - Discrimination by contractors and permittees prohibited.

Code of Federal Regulations, 2012 CFR

2012-10-01

... permittees prohibited. 3.3 Section 3.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.3 Discrimination by contractors and permittees prohibited. The provisions of part III of Executive...

50 CFR 3.3 - Discrimination by contractors and permittees prohibited.

Code of Federal Regulations, 2010 CFR

2010-10-01

... permittees prohibited. 3.3 Section 3.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.3 Discrimination by contractors and permittees prohibited. The provisions of part III of Executive...

50 CFR 3.3 - Discrimination by contractors and permittees prohibited.

Code of Federal Regulations, 2011 CFR

2011-10-01

... permittees prohibited. 3.3 Section 3.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.3 Discrimination by contractors and permittees prohibited. The provisions of part III of Executive...

25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

Code of Federal Regulations, 2010 CFR

2010-04-01

... of the tribe to assert sovereign immunity as a defense in an action brought against the tribe; or (iii) Includes an express waiver of the right of the tribe to assert sovereign immunity as a defense in...

25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

Code of Federal Regulations, 2013 CFR

2013-04-01

... of the tribe to assert sovereign immunity as a defense in an action brought against the tribe; or (iii) Includes an express waiver of the right of the tribe to assert sovereign immunity as a defense in...

25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

Code of Federal Regulations, 2011 CFR

2011-04-01

... of the tribe to assert sovereign immunity as a defense in an action brought against the tribe; or (iii) Includes an express waiver of the right of the tribe to assert sovereign immunity as a defense in...

Role of PTEN in the Tumor Microenvironment

DTIC Science & Technology

2009-06-01

OS, Boers M, Molthoff CF, van Diest PJ. (2008). Hexokinase III, cyclin A and galectin - 3 are overexpressed in malignant follicular thyroid nodules...2009 2. REPORT TYPE Annual 3 . DATES COVERED (From - To) 4. TITLE AND SUBTITLE Role of PTEN in the Tumor Microenvironment 5a. CONTRACT NUMBER...

48 CFR 1652.244-70 - Subcontracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... price analysis; (5) The subcontractor's current, complete, and accurate cost or pricing data and a Certificate of Current Cost or Pricing Data must be submitted to the Contracting officer if required by law... controlling establishment of initial or revised prices; (iii) An explanation of the reason cost or pricing...

13 CFR 125.2 - Prime contracting assistance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... participation unlikely; (ii) Seeks to package or consolidate discrete construction projects; or (iii) Meets the... participation unlikely, or if a proposed procurement for construction seeks to package or consolidate discrete... discrete projects. (5) In conjunction with their duties to promote the set-aside of procurements for small...

13 CFR 125.2 - Prime contracting assistance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... participation unlikely; (ii) Seeks to package or consolidate discrete construction projects; or (iii) Meets the... participation unlikely, or if a proposed procurement for construction seeks to package or consolidate discrete... discrete projects. (5) In conjunction with their duties to promote the set-aside of procurements for small...

13 CFR 125.2 - Prime contracting assistance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... participation unlikely; (ii) Seeks to package or consolidate discrete construction projects; or (iii) Meets the... participation unlikely, or if a proposed procurement for construction seeks to package or consolidate discrete... discrete projects. (5) In conjunction with their duties to promote the set-aside of procurements for small...

Electronic Properties of III-V Semiconductor Interfaces.

DTIC Science & Technology

1980-11-30

ONG . REPORT NUMBER S.B CONTRACT 0R GRANT NUMSERa) S. PERFORMING ORGANIZATION NAMIE AND ADDRESS 10. PROGRAM EL.EMIENT. PROJECT. TASK AREA G WORK UNIT...Fred Nedoluha, Dave Collins, Larry Mainers, Derek Lile, and Carl Zeisse. And several of the samples studied were supplied by industrial colleagues

26 CFR 1.56(g)-0 - Table of Contents.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Treatment of death benefits. (vi) Other rules. (A) Term life insurance contracts without net surrender... for adjusted current earnings. (5) General rule for applying Internal Revenue Code provisions in...) Property subject to new ACRS. (i) In general. (ii) Rules for computing the depreciation deduction. (iii...

48 CFR 32.503-6 - Suspension or reduction of payments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... shall— (i) Act fairly and reasonably; (ii) Base decisions on substantial evidence; and (iii) Document... the contract. This includes the requirement to maintain an efficient and reliable accounting system... associated with the unacceptable portion of the contractor's accounting system shall be suspended) until the...

48 CFR 252.223-7002 - Safety precautions for ammunition and explosives.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ammunition and explosives. 252.223-7002 Section 252.223-7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT...) Ammunition; (iii) Rockets; (iv) Missiles; (v) Warheads; (vi) Devices; and (vii) Components of (i) through (vi...

48 CFR 252.223-7002 - Safety precautions for ammunition and explosives.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ammunition and explosives. 252.223-7002 Section 252.223-7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT...) Ammunition; (iii) Rockets; (iv) Missiles; (v) Warheads; (vi) Devices; and (vii) Components of (i) through (vi...

48 CFR 252.223-7002 - Safety precautions for ammunition and explosives.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ammunition and explosives. 252.223-7002 Section 252.223-7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT...) Ammunition; (iii) Rockets; (iv) Missiles; (v) Warheads; (vi) Devices; and (vii) Components of (i) through (vi...

12 CFR 956.6 - Use of hedging instruments.

Code of Federal Regulations, 2011 CFR

2011-01-01

...; (iii) A description of early termination pricing and methodology, with the methodology reflecting a... International Swaps and Derivatives Association, Inc. language relative to early termination pricing and... obtained prior to the transfer of an agreement or contract by a counterparty. [66 FR 8321, Jan. 30, 2001] ...

48 CFR 27.409 - Solicitation provisions and contract clauses

Code of Federal Regulations, 2011 CFR

2011-10-01

... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

48 CFR 27.409 - Solicitation provisions and contract clauses

Code of Federal Regulations, 2014 CFR

2014-10-01

... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

48 CFR 27.409 - Solicitation provisions and contract clauses

Code of Federal Regulations, 2012 CFR

2012-10-01

... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

48 CFR 27.409 - Solicitation provisions and contract clauses

Code of Federal Regulations, 2013 CFR

2013-10-01

... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

Evidence to Support Peer Tutoring Programs at the Undergraduate Level

ERIC Educational Resources Information Center

Colver, Mitchell; Fry, Trevor

2016-01-01

The present study examined undergraduate peer tutoring in three phases. Phase I qualitatively surveyed students' perceptions about the effectiveness of tutoring. Phase II examined the usefulness of promoting regular use of services through a tutoring contract. Phase III utilized an archival, quasi-experimental approach to estimate the effect of…

13 CFR 108.50 - Definition of terms.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., management, contract, or otherwise, are under the Control of one group or Person. Two or more NMVC companies... that the non-rated debt instrument is equivalent in risk to the issuer's investment grade debt... NMVC Company; (ii) A Control Person, employee or agent of a Partnership NMVC Company; (iii) A managing...

13 CFR 108.50 - Definition of terms.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., management, contract, or otherwise, are under the Control of one group or Person. Two or more NMVC companies... that the non-rated debt instrument is equivalent in risk to the issuer's investment grade debt... NMVC Company; (ii) A Control Person, employee or agent of a Partnership NMVC Company; (iii) A managing...

13 CFR 108.50 - Definition of terms.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., management, contract, or otherwise, are under the Control of one group or Person. Two or more NMVC companies... that the non-rated debt instrument is equivalent in risk to the issuer's investment grade debt... NMVC Company; (ii) A Control Person, employee or agent of a Partnership NMVC Company; (iii) A managing...

13 CFR 108.50 - Definition of terms.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., management, contract, or otherwise, are under the Control of one group or Person. Two or more NMVC companies... that the non-rated debt instrument is equivalent in risk to the issuer's investment grade debt... NMVC Company; (ii) A Control Person, employee or agent of a Partnership NMVC Company; (iii) A managing...

48 CFR 242.705-2 - Auditor determination procedure.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Auditor determination... Indirect Cost Rates 242.705-2 Auditor determination procedure. (b) Procedures. (2)(iii) When agreement cannot be reached with the contractor, the auditor will issue a DCAA Form 1, Notice of Contract Costs...

48 CFR 12.102 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... item in FAR 2.101, if the contract or task order— (i) Is entered into on or before November 24, 2013; (ii) Has a value of $29.5 million or less; (iii) Meets the definition of performance-based acquisition at FAR 2.101; (iv) Uses a quality assurance surveillance plan; (v) Includes performance incentives...

48 CFR 9.406-2 - Causes for debarment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... laws, or receiving stolen property; (4) Intentionally affixing a label bearing a “Made in America... terms of one or more contracts; or (B) A history of failure to perform, or of unsatisfactory performance... drug-free workplace (see 23.504). (iii) Intentionally affixing a label bearing a “Made in America...

17 CFR 200.735-11 - Statement of employment and financial interests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Regulation Concerning... the Ethics in Government Act of 1978, Pub. L. 95-521. Members and such employees need not also file... Fellowship Programs. (iii) All employees engaged in any aspect of Government contracting or procurement...

46 CFR 174.355 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Dry Cargo Ships § 174.355 Definitions. New ship means a... absence of a contract, the construction work of which is begun on or after August 1, 1992; or (iii) Which...

34 CFR 403.190 - What are the requirements for receiving a subgrant or contract?

Code of Federal Regulations, 2010 CFR

2010-07-01

... assessed and the planned use of funds to meet those needs; (iii) How access to programs of good quality will be provided to students who are economically disadvantaged (including foster children), students with disabilities, and students of limited English proficiency through affirmative outreach and...

48 CFR 2152.244-70 - Subcontracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... cost or pricing data and Certificate of Current Cost or Pricing Data, if required by other contract... consideration controlling establishment of initial or revised prices; (iii) The reason cost or pricing data were... subcontractor's cost or pricing data in determining the price objective and in negotiating the final price; (v...

22 CFR 201.24 - Progress and advance payments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... are payments to a supplier prior to, and in anticipation of, performance under a procurement contract. They are not based on actual performance or actual costs incurred. (b) Progress payments—(1) Conditions... predelivery costs that may have a material impact on a suppliers's working capital; (iii) The total FAS...

48 CFR 242.705-2 - Auditor determination procedure.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Auditor determination... Indirect Cost Rates 242.705-2 Auditor determination procedure. (b) Procedures. (2)(iii) When agreement cannot be reached with the contractor, the auditor will issue a DCAA Form 1, Notice of Contract Costs...

76 FR 722 - Governance Requirements for Derivatives Clearing Organizations, Designated Contract Markets, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-06

... regulations to implement core principles concerning governance fitness standards and the composition of...(c) of the CEA to include new DCO Core Principle O (Governance Fitness Standards), P (Conflicts of... owners and participants; (ii) appropriate fitness standards for directors, members, and others; (iii...

26 CFR 521.101 - Introductory.

Code of Federal Regulations, 2010 CFR

2010-04-01

... DENMARK General Income Tax Taxation of Nonresident Aliens Who Are Residents of Denmark and of Danish... representative; and in the case of Denmark, the Chief of the Taxation Department of the Ministry of Finance... III (1) An enterprise of one of the contracting States shall not be subject to taxation in the other...

48 CFR 252.225-7013 - Duty-free entry.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the Buy American Act-Free Trade Agreements-Balance of Payments Program clause of this contract; or (iii) Canadian end product as defined in Alternate I of the Buy American Act-Free Trade Agreements... product have the meanings given in the Trade Agreements clause, the Buy American Act and Balance of...

48 CFR 252.227-7015 - Technical data-Commercial items.

Code of Federal Regulations, 2013 CFR

2013-10-01

... support contractor means a contractor under a contract, the primary purpose of which is to furnish...) Form, fit, and function data means technical data that describes the required overall physical... another party; (ii) Are form, fit, and function data; (iii) Are a correction or change to technical data...

48 CFR 252.227-7015 - Technical data-Commercial items.

Code of Federal Regulations, 2012 CFR

2012-10-01

... support contractor means a contractor under a contract, the primary purpose of which is to furnish...) Form, fit, and function data means technical data that describes the required overall physical... another party; (ii) Are form, fit, and function data; (iii) Are a correction or change to technical data...

48 CFR 252.227-7015 - Technical data-Commercial items.

Code of Federal Regulations, 2011 CFR

2011-10-01

... support contractor means a contractor under a contract, the primary purpose of which is to furnish...) Form, fit, and function data means technical data that describes the required overall physical... another party; (ii) Are form, fit, and function data; (iii) Are a correction or change to technical data...

48 CFR 252.227-7015 - Technical data-Commercial items.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) under a contract, the primary purpose of which is to furnish independent and impartial advice or... Government-Furnished Information Marked with Restrictive Legends. (3) Form, fit, and function data means..., fit, and function data; (iii) Are a correction or change to technical data furnished to the Contractor...

Effects of Persistent Atrial Fibrillation-Induced Electrical Remodeling on Atrial Electro-Mechanics - Insights from a 3D Model of the Human Atria.

PubMed

Adeniran, Ismail; MacIver, David H; Garratt, Clifford J; Ye, Jianqiao; Hancox, Jules C; Zhang, Henggui

2015-01-01

Atrial stunning, a loss of atrial mechanical contraction, can occur following a successful cardioversion. It is hypothesized that persistent atrial fibrillation-induced electrical remodeling (AFER) on atrial electrophysiology may be responsible for such impaired atrial mechanics. This simulation study aimed to investigate the effects of AFER on atrial electro-mechanics. A 3D electromechanical model of the human atria was developed to investigate the effects of AFER on atrial electro-mechanics. Simulations were carried out in 3 conditions for 4 states: (i) the control condition, representing the normal tissue (state 1) and the tissue 2-3 months after cardioversion (state 2) when the atrial tissue recovers its electrophysiological properties after completion of reverse electrophysiological remodelling; (ii) AFER-SR condition for AF-remodeled tissue with normal sinus rhythm (SR) (state 3); and (iii) AFER-AF condition for AF-remodeled tissue with re-entrant excitation waves (state 4). Our results indicate that at the cellular level, AFER (states 3 & 4) abbreviated action potentials and reduced the Ca2+ content in the sarcoplasmic reticulum, resulting in a reduced amplitude of the intracellular Ca2+ transient leading to decreased cell active force and cell shortening as compared to the control condition (states 1 & 2). Consequently at the whole organ level, atrial contraction in AFER-SR condition (state 3) was dramatically reduced. In the AFER-AF condition (state 4) atrial contraction was almost abolished. This study provides novel insights into understanding atrial electro-mechanics illustrating that AFER impairs atrial contraction due to reduced intracellular Ca2+ transients.

Diffusive Shock Acceleration and Reconnection Acceleration Processes

NASA Astrophysics Data System (ADS)

Zank, G. P.; Hunana, P.; Mostafavi, P.; Le Roux, J. A.; Li, Gang; Webb, G. M.; Khabarova, O.; Cummings, A.; Stone, E.; Decker, R.

2015-12-01

Shock waves, as shown by simulations and observations, can generate high levels of downstream vortical turbulence, including magnetic islands. We consider a combination of diffusive shock acceleration (DSA) and downstream magnetic-island-reconnection-related processes as an energization mechanism for charged particles. Observations of electron and ion distributions downstream of interplanetary shocks and the heliospheric termination shock (HTS) are frequently inconsistent with the predictions of classical DSA. We utilize a recently developed transport theory for charged particles propagating diffusively in a turbulent region filled with contracting and reconnecting plasmoids and small-scale current sheets. Particle energization associated with the anti-reconnection electric field, a consequence of magnetic island merging, and magnetic island contraction, are considered. For the former only, we find that (i) the spectrum is a hard power law in particle speed, and (ii) the downstream solution is constant. For downstream plasmoid contraction only, (i) the accelerated spectrum is a hard power law in particle speed; (ii) the particle intensity for a given energy peaks downstream of the shock, and the distance to the peak location increases with increasing particle energy, and (iii) the particle intensity amplification for a particular particle energy, f(x,c/{c}0)/f(0,c/{c}0), is not 1, as predicted by DSA, but increases with increasing particle energy. The general solution combines both the reconnection-induced electric field and plasmoid contraction. The observed energetic particle intensity profile observed by Voyager 2 downstream of the HTS appears to support a particle acceleration mechanism that combines both DSA and magnetic-island-reconnection-related processes.

Strengthening district health service management and delivery through internal contracting: lessons from pilot projects in Cambodia.

PubMed

Khim, Keovathanak; Annear, Peter Leslie

2013-11-01

Following a decade of piloting different models of contracting, in mid-2009 the Cambodian Ministry of Health began to test a form of 'internal contracting' for health care delivery in selected health districts (including hospitals and health centers) contracted by the provincial health department as Special Operating Agencies (SOAs) and provided with greater management autonomy. This study assesses the internal contracting approach as a means for improving the management of district health services and strengthening service delivery. While the study may contribute to the emerging field now known as performance-based financing, the lessons deal more broadly with the impact of management reform and increased autonomy in contrast to traditional public sector line-management and budgeting. Carried out during 2011, the study was based on: (i) a review of the literature and of operational documents; (ii) primary data from semi-structured key informant interviews with 20 health officials in two provinces involved in four SOA pilot districts; and (iii) routine data from the 2011 SOA performance monitoring report. Five prerequisites were identified for effective contract management and improved service delivery: a clear understanding of roles and responsibilities by the contracting parties; implementation of clear rules and procedures; effective management of performance; effective monitoring of the contract; and adequate and timely provision of resources. Both the level and allocation of incentives and management bottlenecks at various levels continue to impede implementation. We conclude that, in contracted arrangements like these, the clear separation of contracting functions (purchasing, commissioning, monitoring and regulating), management autonomy where responsibilities are genuinely devolved and accepted, and the provision of resources adequate to meet contract demands are necessary conditions for success. Copyright © 2013 Elsevier Ltd. All rights reserved.

Reputation and Competition in a Hidden Action Model

PubMed Central

Fedele, Alessandro; Tedeschi, Piero

2014-01-01

The economics models of reputation and quality in markets can be classified in three categories. (i) Pure hidden action, where only one type of seller is present who can provide goods of different quality. (ii) Pure hidden information, where sellers of different types have no control over product quality. (iii) Mixed frameworks, which include both hidden action and hidden information. In this paper we develop a pure hidden action model of reputation and Bertrand competition, where consumers and firms interact repeatedly in a market with free entry. The price of the good produced by the firms is contractible, whilst the quality is noncontractible, hence it is promised by the firms when a contract is signed. Consumers infer future quality from all available information, i.e., both from what they know about past quality and from current prices. According to early contributions, competition should make reputation unable to induce the production of high-quality goods. We provide a simple solution to this problem by showing that high quality levels are sustained as an outcome of a stationary symmetric equilibrium. PMID:25329387

INFINITY construction contract signed

NASA Image and Video Library

2010-04-06

Key state and community leaders celebrated April 6 with the signing of a construction contract for the state-of-the-art INFINITY Science Center planned near John C. Stennis Space Center in south Mississippi. Gulfport Mayor George Schloegel (l to r), chair of non-profit INFINITY Science Center Inc., was joined for the signing ceremony at the Hancock Bank in Gulfport by Virginia Wagner, sister of late Hancock Bank President Leo Seal Jr.; and Roy Anderson III, president and CEO of Roy Anderson Corp. Seal was the first chair of INFINITY Science Center Inc., which has led in development of the project. Roy Anderson Corp. plans to begin construction on the 72,000-square-foot, $28 million science and education center in May. The Mississippi Department of Transportation (MDOT) also is set to begin construction of a $2 million access road to the new center. The April 6 ceremony was attended by numerous officials, including former Stennis Space Center Directors Jerry Hlass and Roy Estess; Mississippi Senate President Pro Tempore Billy Hewes, R-Gulfport; Mississippi Rep. Diane Peranich, D-Pass Christian; and MDOT Southern District Commissioner Wayne Brown.

INFINITY construction contract signed

NASA Technical Reports Server (NTRS)

2010-01-01

Key state and community leaders celebrated April 6 with the signing of a construction contract for the state-of-the-art INFINITY Science Center planned near John C. Stennis Space Center in south Mississippi. Gulfport Mayor George Schloegel (l to r), chair of non-profit INFINITY Science Center Inc., was joined for the signing ceremony at the Hancock Bank in Gulfport by Virginia Wagner, sister of late Hancock Bank President Leo Seal Jr.; and Roy Anderson III, president and CEO of Roy Anderson Corp. Seal was the first chair of INFINITY Science Center Inc., which has led in development of the project. Roy Anderson Corp. plans to begin construction on the 72,000-square-foot, $28 million science and education center in May. The Mississippi Department of Transportation (MDOT) also is set to begin construction of a $2 million access road to the new center. The April 6 ceremony was attended by numerous officials, including former Stennis Space Center Directors Jerry Hlass and Roy Estess; Mississippi Senate President Pro Tempore Billy Hewes, R-Gulfport; Mississippi Rep. Diane Peranich, D-Pass Christian; and MDOT Southern District Commissioner Wayne Brown.

Reputation and competition in a hidden action model.

PubMed

Fedele, Alessandro; Tedeschi, Piero

2014-01-01

The economics models of reputation and quality in markets can be classified in three categories. (i) Pure hidden action, where only one type of seller is present who can provide goods of different quality. (ii) Pure hidden information, where sellers of different types have no control over product quality. (iii) Mixed frameworks, which include both hidden action and hidden information. In this paper we develop a pure hidden action model of reputation and Bertrand competition, where consumers and firms interact repeatedly in a market with free entry. The price of the good produced by the firms is contractible, whilst the quality is noncontractible, hence it is promised by the firms when a contract is signed. Consumers infer future quality from all available information, i.e., both from what they know about past quality and from current prices. According to early contributions, competition should make reputation unable to induce the production of high-quality goods. We provide a simple solution to this problem by showing that high quality levels are sustained as an outcome of a stationary symmetric equilibrium.

Contractility in type III cochlear fibrocytes is dependent on non-muscle myosin II and intercellular gap junctional coupling.

PubMed

Kelly, John J; Forge, Andrew; Jagger, Daniel J

2012-08-01

The cochlear spiral ligament is a connective tissue that plays diverse roles in normal hearing. Spiral ligament fibrocytes are classified into functional sub-types that are proposed to carry out specialized roles in fluid homeostasis, the mediation of inflammatory responses to trauma, and the fine tuning of cochlear mechanics. We derived a secondary sub-culture from guinea pig spiral ligament, in which the cells expressed protein markers of type III or "tension" fibrocytes, including non-muscle myosin II (nmII), α-smooth muscle actin (αsma), vimentin, connexin43 (cx43), and aquaporin-1. The cells formed extensive stress fibers containing αsma, which were also associated intimately with nmII expression, and the cells displayed the mechanically contractile phenotype predicted by earlier modeling studies. cx43 immunofluorescence was evident within intercellular plaques, and the cells were coupled via dye-permeable gap junctions. Coupling was blocked by meclofenamic acid (MFA), an inhibitor of cx43-containing channels. The contraction of collagen lattice gels mediated by the cells could be prevented reversibly by blebbistatin, an inhibitor of nmII function. MFA also reduced the gel contraction, suggesting that intercellular coupling modulates contractility. The results demonstrate that these cells can impart nmII-dependent contractile force on a collagenous substrate, and support the hypothesis that type III fibrocytes regulate tension in the spiral ligament-basilar membrane complex, thereby determining auditory sensitivity.

Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding

PubMed Central

De Andrade, Paula B. M.; Neff, Laurence A.; Strosova, Miriam K.; Arsenijevic, Denis; Patthey-Vuadens, Ophélie; Scapozza, Leonardo; Montani, Jean-Pierre; Ruegg, Urs T.; Dulloo, Abdul G.; Dorchies, Olivier M.

2015-01-01

Weight regain after caloric restriction results in accelerated fat storage in adipose tissue. This catch-up fat phenomenon is postulated to result partly from suppressed skeletal muscle thermogenesis, but the underlying mechanisms are elusive. We investigated whether the reduced rate of skeletal muscle contraction-relaxation cycle that occurs after caloric restriction persists during weight recovery and could contribute to catch-up fat. Using a rat model of semistarvation-refeeding, in which fat recovery is driven by suppressed thermogenesis, we show that contraction and relaxation of leg muscles are slower after both semistarvation and refeeding. These effects are associated with (i) higher expression of muscle deiodinase type 3 (DIO3), which inactivates tri-iodothyronine (T3), and lower expression of T3-activating enzyme, deiodinase type 2 (DIO2), (ii) slower net formation of T3 from its T4 precursor in muscles, and (iii) accumulation of slow fibers at the expense of fast fibers. These semistarvation-induced changes persisted during recovery and correlated with impaired expression of transcription factors involved in slow-twitch muscle development. We conclude that diminished muscle thermogenesis following caloric restriction results from reduced muscle T3 levels, alteration in muscle-specific transcription factors, and fast-to-slow fiber shift causing slower contractility. These energy-sparing effects persist during weight recovery and contribute to catch-up fat. PMID:26441673

Functional morphology and evolution of specialized mouthparts of Cephenniini (Insecta, Coleoptera, Staphylinidae, Scydmaeninae).

PubMed

Jałoszyński, Paweł; Beutel, Rolf G

2012-11-01

We present the results of a morphological study of the labium and labial (premental) discs in Cephenniini, ant-like stone beetles feeding on oribatid mites. The discs are composed of a cuticular plate connected by a circumferential ring with the hypopharyngeal suspensorium. The discs have likely developed from the premental cuticle and from internal sclerotizations of the labium. The shape of the external plate can be changed from flat to concave and vice versa by contractions and relaxations of the labial muscles. Contractions result in a flat or only slightly concave shape whereas during relaxation the discs become strongly concave and adhere tightly to the captured mite. Once this is achieved, detaining of the prey is energy-free. Based on known hypotheses concerning the evolution of Oribatida and Staphylinidae, we exclude the possibility of a co-evolution of "proto-Cephenniini" with yet unarmored "proto-Oribatida", and suggest three alternative scenarios: i) the predators co-evolved with a particular early lineage of Oribatida that has acquired the hard armor relatively recently; ii) ancestors of Cephenniini gradually shifted from feeding on other types of prey towards fully armored Oribatida; or iii) the labial discs have originally developed for functions not related to feeding. Copyright © 2012 Elsevier Ltd. All rights reserved.

48 CFR 235.070-1 - Indemnification under research and development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... research and development contracts. 235.070-1 Section 235.070-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.070-1 Indemnification under research and development contracts. (a...

14 CFR Sec. 1-3 - General description of system of accounts and reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... reports. (a) This system of accounts and reports is designed to permit limited contraction or expansion to... comparability as between air carriers. In its administration three air carrier groups, designated Group I, Group II, and Group III, respectively (see section 04), are established by the BTS. This grouping will be...

76 FR 76318 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-07

... Defense Business Transformation Agency Contracting Office. PART 204--ADMINISTRATIVE MATTERS 204.402...) * * * (iii) For special notices for small business events, follow the procedures at PGI 205.207(d)(ii). PART... Economy Act order. PART 219--SMALL BUSINESS PROGRAMS 0 22. Section 219.202-1 is added to read as follows...

76 FR 42143 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-18

...\\ strategies; and (iii) firm facilitation transactions.\\8\\ The Subsidy applies to contracts that are executed... qualifying member organizations that participate in that transaction. \\5\\ A dividend strategy is defined as transactions done to achieve a dividend arbitrage involving the purchase, sale and exercise of in-the-money...

38 CFR 36.4362 - Rights and restrictions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... parking areas or facilities. (ii) Any contract or lease, including franchises and licenses, to which a declarant is a party. (iii) The requirements of paragraphs (a)(2)(i) and (ii) of this section do not apply... restrictions are acceptable: (i) A requirement that leases have a minimum initial term of up to 1 year; or (ii...

22 CFR 213.20 - Administrative offset of non-employee debts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Administrative offset of non-employee debts... Administrative Offset § 213.20 Administrative offset of non-employee debts. This subpart provides for USAID's... procedures for contractual offsets accommodated by the Contracts Disputes Act); or (iii) In the case of non...

29 CFR 2550.404c-1 - ERISA section 404(c) plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... investment company described in section 3(a) of the Investment Company Act of 1940, or a series investment... similar institution; (iii) A pooled separate account or a fixed rate investment contract of an insurance... the Securities Act of 1933 or the Investment Company Act of 1940), financial statements and reports...

12 CFR 7.4009 - Applicability of state law to national bank operations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... operations. (a) Authority of national banks. A national bank may exercise all powers authorized to it under... laws that obstruct, impair, or condition a national bank's ability to fully exercise its powers to... they only incidentally affect the exercise of national bank powers: (i) Contracts; (ii) Torts; (iii...

7 CFR 1450.214 - Annual payments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... biofuels as defined by 40 CFR 80.1401; (ii) By 10 percent if the eligible crop is delivered to a biomass conversion facility for conversion to advanced biofuels; (iii) By 25 percent if the eligible crop is..., or advanced biofuels; (2) If the producer violates a term of the contract; or (3) In other...

7 CFR 1450.214 - Annual payments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... biofuels as defined by 40 CFR 80.1401; (ii) By 10 percent if the eligible crop is delivered to a biomass conversion facility for conversion to advanced biofuels; (iii) By 25 percent if the eligible crop is..., or advanced biofuels; (2) If the producer violates a term of the contract; or (3) In other...

7 CFR 1450.214 - Annual payments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... biofuels as defined by 40 CFR 80.1401; (ii) By 10 percent if the eligible crop is delivered to a biomass conversion facility for conversion to advanced biofuels; (iii) By 25 percent if the eligible crop is..., or advanced biofuels; (2) If the producer violates a term of the contract; or (3) In other...

7 CFR 1450.214 - Annual payments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... biofuels as defined by 40 CFR 80.1401; (ii) By 10 percent if the eligible crop is delivered to a biomass conversion facility for conversion to advanced biofuels; (iii) By 25 percent if the eligible crop is..., or advanced biofuels; (2) If the producer violates a term of the contract; or (3) In other...

40 CFR 1039.730 - What ABT reports must I send to EPA?

Code of Federal Regulations, 2011 CFR

2011-07-01

... additional information: (1) Show that your net balance of emission credits from all your participating engine... the buyer and any brokers. (ii) A copy of any contracts related to the trade. (iii) The engine families that generated emission credits for the trade, including the number of emission credits from each...

40 CFR 1054.730 - What ABT reports must I send to EPA?

Code of Federal Regulations, 2011 CFR

2011-07-01

... the following additional information: (1) Show that your net balance of emission credits from all your... of the buyer and any brokers. (ii) A copy of any contracts related to the trade. (iii) The families that generated emission credits for the trade, including the number of emission credits from each...

40 CFR 1054.730 - What ABT reports must I send to EPA?

Code of Federal Regulations, 2010 CFR

2010-07-01

... the following additional information: (1) Show that your net balance of emission credits from all your... of the buyer and any brokers. (ii) A copy of any contracts related to the trade. (iii) The families that generated emission credits for the trade, including the number of emission credits from each...

40 CFR 1045.730 - What ABT reports must I send to EPA?

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Show that your net balance of emission credits from all your participating families in each averaging... brokers. (ii) A copy of any contracts related to the trade. (iii) The families that generated emission credits for the trade, including the number of emission credits from each family. (2) As the buyer, you...

7 CFR Appendix A to Subpart C of... - Model Form of Loan Contract for Electric Distribution Borrowers

Code of Federal Regulations, 2010 CFR

2010-01-01

... business makes such qualification necessary; (iii) has all requisite corporate and legal power to own and... transactions contemplated thereby have been duly authorized by all necessary corporate action and shall not... corporate documents and proceedings of the Borrower necessary for duly authorizing the execution, delivery...

13 CFR 121.1204 - What are the procedures for requesting and granting waivers?

Code of Federal Regulations, 2010 CFR

2010-01-01

... history; (iii) A determination by the contracting officer that there are no known small business... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are the procedures for requesting and granting waivers? 121.1204 Section 121.1204 Business Credit and Assistance SMALL BUSINESS...

48 CFR 42.707 - Cost-sharing rates and limitations on indirect cost rates.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor— (i) Is a new or recently reorganized company, and there is no past or recent record of incurred... volume of sales without a commensurate decline in indirect expenses; or (iii) Seeks to enhance its... those that may reasonably be expected to occur during contract performance, thereby causing a cost...

13 CFR 126.803 - How will SBA process a HUBZone status protest?

Code of Federal Regulations, 2014 CFR

2014-01-01

... appeal by the AA/GC&BD, or designee, pursuant to § 126.805. If SBA upholds the protest, SBA will... against it. If the AA/GCBD subsequently overturns the initial determination or dismissal, the contracting... suspended until an appellate decision is rendered. (iii) If the AA/GCBD affirms the initial determination...

13 CFR 126.803 - How will SBA process a HUBZone status protest?

Code of Federal Regulations, 2013 CFR

2013-01-01

... appeal by the AA/GC&BD, or designee, pursuant to § 126.805. If SBA upholds the protest, SBA will... against it. If the AA/GCBD subsequently overturns the initial determination or dismissal, the contracting... suspended until an appellate decision is rendered. (iii) If the AA/GCBD affirms the initial determination...

13 CFR 126.803 - How will SBA process a HUBZone status protest?

Code of Federal Regulations, 2012 CFR

2012-01-01

... appeal by the AA/GC&BD, or designee, pursuant to § 126.805. If SBA upholds the protest, SBA will... against it. If the AA/GCBD subsequently overturns the initial determination or dismissal, the contracting... suspended until an appellate decision is rendered. (iii) If the AA/GCBD affirms the initial determination...

24 CFR 115.204 - Criteria for adequacy of law.

Code of Federal Regulations, 2010 CFR

2010-04-01

... the agency's decision-making authority to be contracted out or delegated to a non-governmental authority. For the purposes of this paragraph, “decision-making authority” includes but is not limited to...; (4) Any action specified in § 115.204(a)(2)(iii) or (b)(1); and (5) Any decision-making regarding...

12 CFR 324.37 - Collateralized transactions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... institution may assign a zero percent risk weight to an exposure to an OTC derivative contract that is marked... exposure to a sovereign that qualifies for a zero percent risk weight under § 324.32. (iii) An FDIC-supervised institution may assign a zero percent risk weight to the collateralized portion of an exposure...

12 CFR 217.37 - Collateralized transactions.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... Notwithstanding paragraph (b)(2)(i) of this section: (i) A Board-regulated institution may assign a zero percent... the extent that the contract is collateralized by an exposure to a sovereign that qualifies for a zero percent risk weight under § 217.32. (iii) A Board-regulated institution may assign a zero percent risk...

13 CFR 127.303 - How will SBA select and identify approved certifiers?

Code of Federal Regulations, 2010 CFR

2010-01-01

... WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Certification of EDWOSB or WOSB Status... 51 percent owned and controlled by one or more women who are United States citizens; and (iii) In the... more women who are United States citizens and economically disadvantaged. (3) It will not decline to...

32 CFR 3.9 - Follow-on production contracts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... proposed quantity and target prices for the follow-on production units as part of that competition. (3... used; (ii) How the production quantities and target prices were evaluated in the competition; (iii) The... condition set forth in law that requires non-Federal parties to the OT agreement to provide at least one...

48 CFR 22.1003-6 - Repair distinguished from remanufacturing of equipment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... overhauled are restored to original life expectancy, or nearly so. (vii) Such work is performed in a facility... replaced. (iii) The item or equipment is rebuilt or reassembled. (iv) The contract work results in the furnishing of a substantially modified item in a usable and serviceable condition. (v) The work is performed...

Third Expert Consultation on RAMP (RAMP III) (Helsinki, Finland, September 13, 15 and 20, 1986). Final Report.

ERIC Educational Resources Information Center

United Nations Educational, Scientific and Cultural Organization, Paris (France). General Information Programme.

Organized for the United Nations Educational, Scientific, and Cultural Organization (Unesco) by contract with the International Council on Archives (ICA), this meeting concerning the Records and Archives Management Programme (RAMP) was attended by 14 experts invited from Unesco member countries. Following a brief introduction, summaries are…

48 CFR 335.071 - Special determinations and findings affecting research and development contracting.

Code of Federal Regulations, 2010 CFR

2010-10-01

... findings affecting research and development contracting. 335.071 Section 335.071 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 335.071 Special determinations and findings affecting research and development contracting. OPDIV...

Fatigue-related firing of distal muscle nociceptors reduces voluntary activation of proximal muscles of the same limb.

PubMed

Kennedy, David S; McNeil, Chris J; Gandevia, Simon C; Taylor, Janet L

2014-02-15

With fatiguing exercise, firing of group III/IV muscle afferents reduces voluntary activation and force of the exercised muscles. These afferents can also act across agonist/antagonist pairs, reducing voluntary activation and force in nonfatigued muscles. We hypothesized that maintained firing of group III/IV muscle afferents after a fatiguing adductor pollicis (AP) contraction would decrease voluntary activation and force of AP and ipsilateral elbow flexors. In two experiments (n = 10) we examined voluntary activation of AP and elbow flexors by measuring changes in superimposed twitches evoked by ulnar nerve stimulation and transcranial magnetic stimulation of the motor cortex, respectively. Inflation of a sphygmomanometer cuff after a 2-min AP maximal voluntary contraction (MVC) blocked circulation of the hand for 2 min and maintained firing of group III/IV muscle afferents. After a 2-min AP MVC, maximal AP voluntary activation was lower with than without ischemia (56.2 ± 17.7% vs. 76.3 ± 14.6%; mean ± SD; P < 0.05) as was force (40.3 ± 12.8% vs. 57.1 ± 13.8% peak MVC; P < 0.05). Likewise, after a 2-min AP MVC, elbow flexion voluntary activation was lower with than without ischemia (88.3 ± 7.5% vs. 93.6 ± 3.9%; P < 0.05) as was torque (80.2 ± 4.6% vs. 86.6 ± 1.0% peak MVC; P < 0.05). Pain during ischemia was reported as Moderate to Very Strong. Postfatigue firing of group III/IV muscle afferents from the hand decreased voluntary drive and force of AP. Moreover, this effect decreased voluntary drive and torque of proximal unfatigued muscles, the elbow flexors. Fatigue-sensitive group III/IV muscle nociceptors act to limit voluntary drive not only to fatigued muscles but also to unfatigued muscles within the same limb.

Effects of chemically induced contraction of a coordination polyhedron on the dynamical magnetism of bis(phthalocyaninato)disprosium, a single-4f-ionic single-molecule magnet with a Kramers ground state.

PubMed

Ishikawa, Naoto; Mizuno, Yoshifumi; Takamatsu, Satoshi; Ishikawa, Tadahiko; Koshihara, Shin-ya

2008-11-17

Chemically induced longitudinal contraction of the square-antiprism coordination polyhedron of a peripherically substituted bis(phthalocyaninato)dysprosiumate(III), a dysprosium-based single-4f-ionic single-molecule magnet having a J z = +/- (13)/ 2 Kramers doublet ground state, resulted in drastic changes in dynamical magnetism including a doubling of the energy barrier, a 2-order-of-magnitude decrease of the spin reversal rate, a significant rise of the blocking temperature, and the first observation of the emergence of a large remanent magnetization.

Spray forming -- Aluminum: Third annual report (Phase 2). Technical progress -- Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kozarek, R.L.

1998-04-20

Commercial production of aluminum sheet and plate by spray atomization and deposition is a potentially attractive manufacturing alternative to conventional ingot metallurgy/hot-milling and to continuous casting processes because of reduced energy requirements and reduced cost. To realize the full potential of the technology, the Aluminum Company of America (Alcoa), under contract by the US Department of Energy, is investigating currently available state-of-the-art atomization devices to develop nozzle design concepts whose spray characteristics are tailored for continuous sheet production. This third technical progress report will summarize research and development work conducted during the period 1997 October through 1998 March. Included aremore » the latest optimization work on the Alcoa III nozzle, results of spray forming runs with 6111 aluminum alloy and preliminary rolling trials of 6111 deposits.« less

The Discriminant Analysis Flare Forecasting System (DAFFS)

NASA Astrophysics Data System (ADS)

Leka, K. D.; Barnes, Graham; Wagner, Eric; Hill, Frank; Marble, Andrew R.

2016-05-01

The Discriminant Analysis Flare Forecasting System (DAFFS) has been developed under NOAA/Small Business Innovative Research funds to quantitatively improve upon the NOAA/SWPC flare prediction. In the Phase-I of this project, it was demonstrated that DAFFS could indeed improve by the requested 25% most of the standard flare prediction data products from NOAA/SWPC. In the Phase-II of this project, a prototype has been developed and is presently running autonomously at NWRA.DAFFS uses near-real-time data from NOAA/GOES, SDO/HMI, and the NSO/GONG network to issue both region- and full-disk forecasts of solar flares, based on multi-variable non-parametric Discriminant Analysis. Presently, DAFFS provides forecasts which match those provided by NOAA/SWPC in terms of thresholds and validity periods (including 1-, 2-, and 3- day forecasts), although issued twice daily. Of particular note regarding DAFFS capabilities are the redundant system design, automatically-generated validation statistics and the large range of customizable options available. As part of this poster, a description of the data used, algorithm, performance and customizable options will be presented, as well as a demonstration of the DAFFS prototype.DAFFS development at NWRA is supported by NOAA/SBIR contracts WC-133R-13-CN-0079 and WC-133R-14-CN-0103, with additional support from NASA contract NNH12CG10C, plus acknowledgment to the SDO/HMI and NSO/GONG facilities and NOAA/SWPC personnel for data products, support, and feedback. DAFFS is presently ready for Phase-III development.

23 CFR Appendix C to Subpart B of... - Additional Required Contract Provisions, Appalachian Development Highway System and Local Access...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Additional Required Contract Provisions, Appalachian Development Highway System and Local Access Roads Contracts Other Than Construction Contracts C Appendix C to..., Appalachian Development Highway System and Local Access Roads Contracts Other Than Construction Contracts...

Wound healing activity of Sida cordifolia Linn. in rats.

PubMed

Pawar, Rajesh S; Chaurasiya, Pradeep K; Rajak, Harish; Singour, Pradeep K; Toppo, Fedelic Ashish; Jain, Ankit

2013-01-01

The present study provides a scientific evaluation for the wound healing potential of ethanolic (EtOH) extract of Sida cordifolia Linn. (SCL) plant. Excision, incision and burn wounds were inflicted upon three groups of six rats each. Group I was assigned as control (ointment base). Group II was treated with 10% EtOH extract ointment. Group III was treated with standard silver sulfadiazine (0.01%) cream. The parameters observed were percentage of wound contraction, epithelialization period, hydroxyproline content, tensile strength including histopathological studies. It was noted that the effect produced by the ethanolic extract of SCL ointment showed significant (P < 0.01) healing in all wound models when compared with the control group. All parameters such as wound contraction, epithelialization period, hydroxyproline content, tensile strength and histopathological studies showed significant (P < 0.01) changes when compared with the control. The ethanolic extract ointment of SCL effectively stimulates wound contraction; increases tensile strength of excision, incision and burn wounds.

Prime Contract Awards Over $25,000 by Major System, Contractor and State, Fiscal Year 1987. Part 2. BSP-SMZ.

DTIC Science & Technology

1987-01-01

I - II t. AI OV444V4 W 4 V V 0)4 -4 44 -4 4 0 W 1 . 0W4 _4 m C.) 00IL OIL 00 1,0U 00 0r z I I ~~ I 4 ~ - I ...r- (4 𔃻 =4 V ) 4 I - 4 U) 6’’ 0 4 011 00.0 CL ... ( O 0.)O O( 4 O’ 0 Oil 0~0 )4 - 0 slO) w . ) - ’J1 4*£) CJ.’ ’ 4’C~’ Ax~ I ~0- WO- zI 0 1 00 C COO... I In11 I (D C,~~ f 0- I I II I I I oil III III IIIN lot III t5 I

48 CFR 46.308 - Cost-reimbursement research and development contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research and development contracts. 46.308 Section 46.308 Federal Acquisition Regulations System FEDERAL... research and development contracts. The contracting officer shall insert the clause at 52.246-8, Inspection of Research and Development—Cost-Reimbursement, in solicitations and contracts for research and...

48 CFR 46.309 - Research and development contracts (short form).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Research and development contracts (short form). 46.309 Section 46.309 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.309 Research and development contracts...

48 CFR 46.308 - Cost-reimbursement research and development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... research and development contracts. 46.308 Section 46.308 Federal Acquisition Regulations System FEDERAL... research and development contracts. The contracting officer shall insert the clause at 52.246-8, Inspection of Research and Development—Cost-Reimbursement, in solicitations and contracts for research and...

24 CFR 246.8 - Materials to be submitted to HUD in support of preemption request.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Commissioner, audited by an independent public accountant and covering the most recently ended accounting year... by the following: (i) Tax rates or appraisals, (ii) Utility rates, (iii) Contracts for employees or... experienced by the project which have been approved and can be documented as follows: (i) Tax rates or...

The Center for In-Service Education. Final Evaluation Report. Volume II. Part 1.

ERIC Educational Resources Information Center

Tennessee State Dept. of Education, Nashville.

This is an overview of the extensive in-service education inventory conducted as an integral portion of the planning contract for Models for In-Service Education supported by the Tennessee State Department of Education under Title III, Elementary and Secondary Education Act. The narrative descriptions are free of extensive statistical references…

17 CFR 240.14d-9 - Recommendation or solicitation by the subject company and others.

Code of Federal Regulations, 2010 CFR

2010-04-01

... information and/or advice regarding such tender offer to their customers or clients on the unsolicited request of such customers or clients or solely pursuant to a contract or a relationship providing for advice to the customer or client to whom the information and/or advice is given. (iii) Any person specified...

Theranostics Targeting Metastatic Breast Cancer

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-15-1-0389 TITLE: Theranostics Targeting Metastatic Breast Cancer PRINCIPAL INVESTIGATOR: Kevin Burgess CONTRACTING...ADDRESS. 1. REPORT DATE October 2017 2. REPORT TYPE Annual 3. DATES COVERED 4. TITLE AND SUBTITLE Theranostics Targeting Metastatic Breast Cancer 5a...safe and effective interventions; (ii) elimination of mortality associated with metastatic breast cancer ; and, (iii) distinguishing aggressive breast

76 FR 61279 - Defense Federal Acquisition Regulation Supplement; Defense Cargo Riding Gang Member (DFARS Case...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

... transportation services. The final rule also makes an administrative change to a cross-reference. DATES....S.-flag vessels under DoD contracts for transportation services documented under chapter 121, title... cross-reference to 252.211-7006 at 212.301(f)(iv)(D) to reflect the correct title of the clause. III...

Bibliography of In-House and Contract Reports. Supplement 9.

DTIC Science & Technology

1981-02-01

11;il CasCil roads andl ril roads would significantlN rcduLcc tlic ~anIual labor IMnOls d III V, i 1111111 d il.1 . graphic data bascs. ile effort...GUIDE FOR CLIMA TE (Rpt. No. 5 in the ETL Series on Guides for Army Terrain Analysts) September 1980 Keywords: Climatic Analysis, Factor Mapping

26 CFR 1.6049-2 - Interest and original issue discount subject to reporting in calendar years before 1983.

Code of Federal Regulations, 2013 CFR

2013-04-01

... life insurance or endowment contracts does not constitute interest for purposes of this section. (5... obligations. (2) Any payment by: (i) A foreign corporation, (ii) A nonresident alien individual, or (iii) A partnership composed in whole or in part of nonresident aliens, if such corporation, individual, or...

26 CFR 1.6049-2 - Interest and original issue discount subject to reporting in calendar years before 1983.

Code of Federal Regulations, 2011 CFR

2011-04-01

... life insurance or endowment contracts does not constitute interest for purposes of this section. (5... obligations. (2) Any payment by: (i) A foreign corporation, (ii) A nonresident alien individual, or (iii) A partnership composed in whole or in part of nonresident aliens, if such corporation, individual, or...

26 CFR 1.6049-2 - Interest and original issue discount subject to reporting in calendar years before 1983.

Code of Federal Regulations, 2012 CFR

2012-04-01

... life insurance or endowment contracts does not constitute interest for purposes of this section. (5... obligations. (2) Any payment by: (i) A foreign corporation, (ii) A nonresident alien individual, or (iii) A partnership composed in whole or in part of nonresident aliens, if such corporation, individual, or...

26 CFR 1.6049-2 - Interest and original issue discount subject to reporting in calendar years before 1983.

Code of Federal Regulations, 2014 CFR

2014-04-01

... life insurance or endowment contracts does not constitute interest for purposes of this section. (5... obligations. (2) Any payment by: (i) A foreign corporation, (ii) A nonresident alien individual, or (iii) A partnership composed in whole or in part of nonresident aliens, if such corporation, individual, or...

77 FR 36611 - Core Principles and Other Requirements for Designated Contract Markets

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-19

.... 38.154--Regulatory Services Provided by a Third Party vi. Sec. 38.155--Compliance Staff and Resources... vi. Sec. 38.256--Trade Reconstruction vii. Sec. 38.257--Regulatory Service Provider viii. Sec. 38.258... Integrity iii. Sec. 38.603--Protection of Customer Funds iv. Sec. 38.604--Financial Surveillance v. Sec. 38...

78 FR 56762 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-13

... contracts for Market Makers \\3\\ registered on the Exchange. \\3\\ Market Makers may be registered as a Lead Market Maker or as a Registered Market Maker. See Exchange Rule 600(b). Market Makers registered on the...) Registered Market Maker (``RMM''); (ii) Lead Market Maker (``LMM''); (iii) Directed Order Lead Market Maker...

26 CFR 1.197-1T - Certain elections for intangible property (temporary).

Code of Federal Regulations, 2011 CFR

2011-04-01

... retroactive election under paragraph (c)(6) of this section, identification of such persons and certification...) Identification of the property affected by the binding contract election, the name and TIN of the person from... purposes of re-applying the rule of this paragraph (c)(1)(ii) to any other taxpayer. (iii) On former...

17 CFR 240.14d-9 - Recommendation or solicitation by the subject company and others.

Code of Federal Regulations, 2012 CFR

2012-04-01

... information and/or advice regarding such tender offer to their customers or clients on the unsolicited request of such customers or clients or solely pursuant to a contract or a relationship providing for advice to the customer or client to whom the information and/or advice is given. (iii) Any person specified...

17 CFR 240.14d-9 - Recommendation or solicitation by the subject company and others.

Code of Federal Regulations, 2013 CFR

2013-04-01

... information and/or advice regarding such tender offer to their customers or clients on the unsolicited request of such customers or clients or solely pursuant to a contract or a relationship providing for advice to the customer or client to whom the information and/or advice is given. (iii) Any person specified...

The proximal gastric corpus is the most responsive site of motilin-induced contractions in the stomach of the Asian house shrew.

PubMed

Dudani, Amrita; Aizawa, Sayaka; Zhi, Gong; Tanaka, Toru; Jogahara, Takamichi; Sakata, Ichiro; Sakai, Takafumi

2016-07-01

The migrating motor complex (MMC) is responsible for emptying the stomach during the interdigestive period, in preparation for the next meal. It is known that gastric phase III of MMC starts from the proximal stomach and propagates the contraction downwards. We hypothesized that a certain region of the stomach must be more responsive to motilin than others, and that motilin-induced strong gastric contractions propagate from that site. Stomachs of the Suncus or Asian house shrew, a small insectivorous mammal, were dissected and the fundus, proximal corpus, distal corpus, and antrum were examined to study the effect of motilin using an organ bath experiment. Motilin-induced contractions differed in different parts of the stomach. Only the proximal corpus induced gastric contraction even at motilin 10(-10) M, and strong contraction was induced by motilin 10(-9) M in all parts of the stomach. The GPR38 mRNA expression was also higher in the proximal corpus than in the other sections, and the lowest expression was observed in the antrum. GPR38 mRNA expression varied with low expression in the mucosal layer and high expression in the muscle layer. Additionally, motilin-induced contractions in each dissected part of the stomach were inhibited by tetrodotoxin and atropine pretreatment. These results suggest that motilin reactivity is not consistent throughout the stomach, and an area of the proximal corpus including the cardia is the most sensitive to motilin.

Effects of Persistent Atrial Fibrillation-Induced Electrical Remodeling on Atrial Electro-Mechanics – Insights from a 3D Model of the Human Atria

PubMed Central

Adeniran, Ismail; MacIver, David H.; Garratt, Clifford J.; Ye, Jianqiao; Hancox, Jules C.; Zhang, Henggui

2015-01-01

Aims Atrial stunning, a loss of atrial mechanical contraction, can occur following a successful cardioversion. It is hypothesized that persistent atrial fibrillation-induced electrical remodeling (AFER) on atrial electrophysiology may be responsible for such impaired atrial mechanics. This simulation study aimed to investigate the effects of AFER on atrial electro-mechanics. Methods and Results A 3D electromechanical model of the human atria was developed to investigate the effects of AFER on atrial electro-mechanics. Simulations were carried out in 3 conditions for 4 states: (i) the control condition, representing the normal tissue (state 1) and the tissue 2–3 months after cardioversion (state 2) when the atrial tissue recovers its electrophysiological properties after completion of reverse electrophysiological remodelling; (ii) AFER-SR condition for AF-remodeled tissue with normal sinus rhythm (SR) (state 3); and (iii) AFER-AF condition for AF-remodeled tissue with re-entrant excitation waves (state 4). Our results indicate that at the cellular level, AFER (states 3 & 4) abbreviated action potentials and reduced the Ca2+ content in the sarcoplasmic reticulum, resulting in a reduced amplitude of the intracellular Ca2+ transient leading to decreased cell active force and cell shortening as compared to the control condition (states 1 & 2). Consequently at the whole organ level, atrial contraction in AFER-SR condition (state 3) was dramatically reduced. In the AFER-AF condition (state 4) atrial contraction was almost abolished. Conclusions This study provides novel insights into understanding atrial electro-mechanics illustrating that AFER impairs atrial contraction due to reduced intracellular Ca2+ transients. PMID:26606047

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 2035.70 Contract clauses. (a) The contracting officer shall insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

Analysis of Morphological Characteristics and Origins of Idiopathic Premature Ventricular Contractions Under a 12-Lead Electrocardiogram in Children with Structurally Normal Hearts.

PubMed

Jiang, Jianbin; He, Yuee; Qiu, Huixian; Zhang, Yuanhai; Chu, Maoping; Li, Yuechun; Chen, Qi

2017-10-21

Up to 40% of healthy children have premature ventricular complexes or contractions (PVCs) detected with 24-hour Holter monitoring. We aimed to investigate the morphological characteristics and origins of idiopathic PVCs under a 12-lead electrocardiogram in children with structurally normal hearts. All asymptomatic monomorphic PVC patients with structurally normal hearts under 18 years of age were included in this retrospective study. Characteristics of PVCs in lead V 1 under a 12-lead electrocardiogram were classified as left bundle branch block (PVC-LBBB) or right bundle branch block (PVC-RBBB). According to limb leads, PVC-LBBB or PVC-RBBB was divided into: PVCs-LBBB type I; PVCs-LBBB type II; PVCs-RBBB type I; PVCs-RBBB type II; and PVCs-RBBB type III. Out of 178 PVC patients, 94 cases of PVCs-LBBB (PVCs-LBBB type I = 60; PVCs-LBBB type II = 34) and 84 cases of PVCs-RBBB (PVCs-RBBB type I = 3; PVCs-RBBB type II = 55; PVCs-RBBB type III = 26) were identified. The frequency of PVCs-LBBB type I increased with age and the frequency of PVCs-RBBB type II and III decreased with age. Among the children monitor tested, from 1 years old to 18 years old, PVCs originating from the left or right ventricular outflow tract gradually increased with age, while PVCs originating from the branch sources decreased with age.

Multiple Loops of the Dihydropyridine Receptor Pore Subunit Are Required for Full-Scale Excitation-Contraction Coupling in Skeletal Muscle

PubMed Central

Carbonneau, Leah; Bhattacharya, Dipankar; Sheridan, David C.; Coronado, Roberto

2005-01-01

Understanding which cytosolic domains of the dihydropyridine receptor participate in excitation-contraction (EC) coupling is critical to validate current structural models. Here we quantified the contribution to skeletal-type EC coupling of the α1S (CaV1.1) II-III loop when alone or in combination with the rest of the cytosolic domains of α1S. Chimeras consisting of α1C (CaV1.2) with α1S substitutions at each of the interrepeat loops (I-II, II-III, and III-IV loops) and N- and C-terminal domains were evaluated in dysgenic (α1S-null) myotubes for phenotypic expression of skeletal-type EC coupling. Myotubes were voltage-clamped, and Ca2+ transients were measured by confocal line-scan imaging of fluo-4 fluorescence. In agreement with previous results, the α1C/α1S II-III loop chimera, but none of the other single-loop chimeras, recovered a sigmoidal fluorescence-voltage curve indicative of skeletal-type EC coupling. To quantify Ca2+ transients in the absence of inward Ca2+ current, but without changing the external solution, a mutation, E736K, was introduced into the P-loop of repeat II of α1C. The Ca2+ transients expressed by the α1C(E736K)/α1S II-III loop chimera were ∼70% smaller than those expressed by the Ca2+-conducting α1C/α1S II-III variant. The low skeletal-type EC coupling expressed by the α1C/α1S II-III loop chimera was confirmed in the Ca2+-conducting α1C/α1S II-III loop variant using Cd2+ (10−4 M) as the Ca2+ current blocker. In contrast to the behavior of the II-III loop chimera, Ca2+ transients expressed by an α1C/α1S chimera carrying all tested skeletal α1S domains (all α1S interrepeat loops, N- and C-terminus) were similar in shape and amplitude to wild-type α1S, and did not change in the presence of the E736K mutation or in the presence of 10−4 M Cd2+. Controls indicated that similar dihydropyridine receptor charge movements were expressed by the non-Ca2+ permeant α1S(E1014K) variant, the α1C(E736K)/α1S II-III loop chimera, and the α1C(E736K)/α1S chimera carrying all tested α1S domains. The data indicate that the functional recovery produced by the α1S II-III loop is incomplete and that multiple cytosolic domains of α1S are necessary for a quantitative recovery of the EC-coupling phenotype of skeletal myotubes. Thus, despite the importance of the II-III loop there may be other critical determinants in α1S that influence the efficiency of EC coupling. PMID:15849247

Tobacco industry influence on the definition of tobacco related disorders by the American Psychiatric Association.

PubMed

Neuman, M D; Bitton, A; Glantz, S A

2005-10-01

The Diagnostic and statistical manual of mental disorders, third edition (DSM-III), published by the American Psychiatric Association (APA) in 1980, included the first official definitions by the APA of tobacco dependence and tobacco withdrawal. Tobacco industry efforts to influence the DSM-III were investigated. Searches of previously secret tobacco industry documents, primarily the University of California San Francisco Legacy Tobacco Documents Library and British American Tobacco collections. Additional information was collected through discussions with editors of DSM-III, and library and general internet searches. The tobacco companies regarded the inclusion of tobacco dependence as a diagnosis in DSM-III as an adverse event. It worked to influence the content of the DSM-III and its impact following publication. These efforts included public statements and private lobbying of DSM-III editors and high ranking APA officers by prominent US psychiatrists with undisclosed ties to the tobacco industry. Following publication of DSM-III, tobacco companies contracted with two US professors of psychiatry to organise a conference and publish a monograph detailing controversies surrounding DSM-III. The tobacco industry and its allies lobbied to narrow the definition of tobacco dependence in serial revisions of DSM-III. Following publication of DSM-III, the industry took steps to try to mitigate its impact. These actions mirror industry tactics to influence medical research and policy in various contexts worldwide. Such tactics slow the spread of a professional and public understanding of smoking and health that otherwise would reduce smoking, smoking induced disease, and tobacco company profits.

Tobacco industry influence on the definition of tobacco related disorders by the American Psychiatric Association

PubMed Central

Neuman, M; Bitton, A; Glantz, S

2005-01-01

Objective: The Diagnostic and statistical manual of mental disorders, third edition (DSM-III), published by the American Psychiatric Association (APA) in 1980, included the first official definitions by the APA of tobacco dependence and tobacco withdrawal. Tobacco industry efforts to influence the DSM-III were investigated. Method: Searches of previously secret tobacco industry documents, primarily the University of California San Francisco Legacy Tobacco Documents Library and British American Tobacco collections. Additional information was collected through discussions with editors of DSM-III, and library and general internet searches. Results: The tobacco companies regarded the inclusion of tobacco dependence as a diagnosis in DSM-III as an adverse event. It worked to influence the content of the DSM-III and its impact following publication. These efforts included public statements and private lobbying of DSM-III editors and high ranking APA officers by prominent US psychiatrists with undisclosed ties to the tobacco industry. Following publication of DSM-III, tobacco companies contracted with two US professors of psychiatry to organise a conference and publish a monograph detailing controversies surrounding DSM-III. Conclusions: The tobacco industry and its allies lobbied to narrow the definition of tobacco dependence in serial revisions of DSM-III. Following publication of DSM-III, the industry took steps to try to mitigate its impact. These actions mirror industry tactics to influence medical research and policy in various contexts worldwide. Such tactics slow the spread of a professional and public understanding of smoking and health that otherwise would reduce smoking, smoking induced disease, and tobacco company profits. PMID:16183984

48 CFR 34.005-5 - Full-scale development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Full-scale development... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 34.005-5 Full-scale development contracts. Whenever practicable, the full-scale development contracts should provide for the contractors to...

48 CFR 34.005-5 - Full-scale development contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Full-scale development... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 34.005-5 Full-scale development contracts. Whenever practicable, the full-scale development contracts should provide for the contractors to...

24 CFR 983.203 - HAP contract information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HAP contract information. 983.203... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Housing Assistance Payments Contract § 983.203 HAP contract information. The HAP contract must specify: (a) The total number of contract units by number of bedrooms; (b...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... all solicitations and contracts for research and development. For further information, see DOT's Implementation Guidance for Executive Office of the President, Office of Science and Technology Policy, “Federal... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause...

Study of Manpower Requirements by Occupation for Alternative Technologies in the Energy-Related Industries, 1970-1990. Volumes I, IIA, and III.

ERIC Educational Resources Information Center

Gutmanis, Ivars; And Others

The report presents the methodology used by the National Planning Association (NPA), under contract to the Federal Energy Administration (FEA), to estimate direct labor usage coefficients in some sixty different occupational categories involved in construction, operation, and maintenance of energy facilities. Volume 1 presents direct labor usage…

A Contract to Encourage Full Utilization of Educational Talent. Final Report 1968-1969.

ERIC Educational Resources Information Center

New Mexico Council for the Development of Educational Talent, Las Vegas.

Goals of the New Mexico Educational Talent Project--funded under Title III of the Elementary and Secondary Education Act--are (1) to identify qualified secondary school students at the 11th grade or earlier and assist them in completing their high school education, (2) to encourage an increasing number of high school students to select a teaching…

29 CFR 5.15 - Limitations, variations, tolerances, and exemptions under the Contract Work Hours and Safety...

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (iii) The time in question does not involve productive work or performance of the apprentice's or... receives gross wages of not less than $300 per week regardless of the total number of hours worked in any workweek, and (B) Within any workweek the total wages which an employee receives are not less than the...

77 FR 43470 - Defense Federal Acquisition Regulation Supplement: Contracting With the Canadian Commercial...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-24

... pricing data. This DFARS rule reiterates at 225.870-4(c)(2), and in paragraph (b)(iii) of both the new... data other than certified cost or pricing data. DATES: Effective date: July 24, 2012. FOR FURTHER... Corporation and its subcontractors to submit certified cost or pricing data (see DFARS 215.403-1(c)(4)(C...

Study of CCD Eyepiece on T-4 Theodolite.

DTIC Science & Technology

1982-11-01

11. REVIEW OF TWO-COLOR REFRACTOMETRY OBJECTIVES .....................3 III, ACHIEVEMENTS IN TWO- COLOR REFRACTOMETRY DURING THIS CONTRA...indirectly influence the questions of star catalogs. The initial efforts under this contract were addressed toward Two- Color Refractometry . This is a...in the astroposition procedure. Future efforts on other projects will consist of the return to the Two-Color Refractometry to provide a parallel

78 FR 26369 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-06

... placement of securities; and engaging under contract with a third party in asset management, servicing, and collection of assets, pursuant to sections 225.28(b)(1), (b)(2)(vi), and (b)(7)(iii), respectively. Board of... novo, or to acquire or control voting securities or assets of a company, including the companies listed...

Neuro-Immune Mechanisms in Response to Venezuelan Equine Encephalitis Virus Infection

DTIC Science & Technology

2000-01-01

iii ABSTRACT NEURO-IMMUNE MECHANISMS IN RESPONSE TO VENEZUELAN EQUINE ENCEPHALITIS VIRUS INFECTION Major Bruce A. Schoneboom directed by Franziska B...Grieder, DVM, Ph.D., Assistant Professor of Microbiology and Immunology, Molecular and Cellular Biology, and Neuroscience Venezuelan equine ...3. DATES COVERED - 4. TITLE AND SUBTITLE NEURO-IMMUNE MECHANISMS IN RESPONSE TO VENEZUELAN EQUINE ENCEPHALITIS VIRUS INFECTION 5a. CONTRACT

Cardiovascular effects of equinatoxin III from the sea anemone Actinia equina (L.).

PubMed

Suput, D; Frangez, R; Bunc, M

2001-09-01

Equinatoxin III is the most hemolytic, and the least lethal of the three basic proteins isolated from the sea anemone Actinia equina (L.). Its LD50 in mice is 83 microg/kg. Preliminary results on Wistar rats have suggested cardiorespiratory arrest as a putative cause of death, but the mechanism of its action has not yet been studied. So far only equinatoxin II has been investigated more thoroughly. As equinatoxin II is less lythic, but more toxic, than equinatoxin III (its LD50 in mice=35 microg/kg), it may be assumed that haemolysis with a consequent rise in plasma potassium level is not the major factor in the lethality of equinatoxins. To assess the relative contribution of hyperkalemia in the lethality of the toxin in rat, the effects of equinatoxin III were compared to the effects of hyperkalemia caused by the injection of KCl giving the same final concentration of K+ in the plasma as that observed after an i.v. injection of 3LD50 of equinatoxin III. As coronary vasoconstriction may be an important mechanism of the cardiotoxic action of equinatoxins, the effect of EqT III on isolated porcine coronary arteries was studied by measurements of smooth muscle tension in the presence of 1-100 nM equinatoxin III. The results revealed that animals survive the elevated K+ plasma concentration caused by an i.v. application of KCl. This suggests that equinatoxin III induced haemolysis is not the major mechanism of equinatoxin III lethality. However, equinatoxin III increases the potassium induced contractions of coronary smooth muscle for 289+/-29%, suggesting that coronary vasoconstriction may be an important factor in the cardiotoxic effects of equinatoxin III.

24 CFR 983.202 - Purpose of HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Purpose of HAP contract. 983.202... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Housing Assistance Payments Contract § 983.202 Purpose of HAP contract. (a) Requirement. The PHA must enter into a HAP contract with the owner. The HAP contract must be...

Advanced, High Power, Next Scale, Wave Energy Conversion Device

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mekhiche, Mike; Dufera, Hiz; Montagna, Deb

2012-10-29

The project conducted under DOE contract DE‐EE0002649 is defined as the Advanced, High Power, Next Scale, Wave Energy Converter. The overall project is split into a seven‐stage, gated development program. The work conducted under the DOE contract is OPT Stage Gate III work and a portion of Stage Gate IV work of the seven stage product development process. The project effort includes Full Concept Design & Prototype Assembly Testing building on our existing PowerBuoy technology to deliver a device with much increased power delivery. Scaling‐up from 150kW to 500kW power generating capacity required changes in the PowerBuoy design that addressedmore » cost reduction and mass manufacturing by implementing a Design for Manufacturing (DFM) approach. The design changes also focused on reducing PowerBuoy Installation, Operation and Maintenance (IO&M) costs which are essential to reducing the overall cost of energy. In this design, changes to the core PowerBuoy technology were implemented to increase capability and reduce both CAPEX and OPEX costs. OPT conceptually envisaged moving from a floating structure to a seabed structure. The design change from a floating structure to seabed structure would provide the implementation of stroke‐ unlimited Power Take‐Off (PTO) which has a potential to provide significant power delivery improvement and transform the wave energy industry if proven feasible.« less

SparseMaps—A systematic infrastructure for reduced-scaling electronic structure methods. III. Linear-scaling multireference domain-based pair natural orbital N-electron valence perturbation theory

NASA Astrophysics Data System (ADS)

Guo, Yang; Sivalingam, Kantharuban; Valeev, Edward F.; Neese, Frank

2016-03-01

Multi-reference (MR) electronic structure methods, such as MR configuration interaction or MR perturbation theory, can provide reliable energies and properties for many molecular phenomena like bond breaking, excited states, transition states or magnetic properties of transition metal complexes and clusters. However, owing to their inherent complexity, most MR methods are still too computationally expensive for large systems. Therefore the development of more computationally attractive MR approaches is necessary to enable routine application for large-scale chemical systems. Among the state-of-the-art MR methods, second-order N-electron valence state perturbation theory (NEVPT2) is an efficient, size-consistent, and intruder-state-free method. However, there are still two important bottlenecks in practical applications of NEVPT2 to large systems: (a) the high computational cost of NEVPT2 for large molecules, even with moderate active spaces and (b) the prohibitive cost for treating large active spaces. In this work, we address problem (a) by developing a linear scaling "partially contracted" NEVPT2 method. This development uses the idea of domain-based local pair natural orbitals (DLPNOs) to form a highly efficient algorithm. As shown previously in the framework of single-reference methods, the DLPNO concept leads to an enormous reduction in computational effort while at the same time providing high accuracy (approaching 99.9% of the correlation energy), robustness, and black-box character. In the DLPNO approach, the virtual space is spanned by pair natural orbitals that are expanded in terms of projected atomic orbitals in large orbital domains, while the inactive space is spanned by localized orbitals. The active orbitals are left untouched. Our implementation features a highly efficient "electron pair prescreening" that skips the negligible inactive pairs. The surviving pairs are treated using the partially contracted NEVPT2 formalism. A detailed comparison between the partial and strong contraction schemes is made, with conclusions that discourage the strong contraction scheme as a basis for local correlation methods due to its non-invariance with respect to rotations in the inactive and external subspaces. A minimal set of conservatively chosen truncation thresholds controls the accuracy of the method. With the default thresholds, about 99.9% of the canonical partially contracted NEVPT2 correlation energy is recovered while the crossover of the computational cost with the already very efficient canonical method occurs reasonably early; in linear chain type compounds at a chain length of around 80 atoms. Calculations are reported for systems with more than 300 atoms and 5400 basis functions.

Quality Metrics of Digitally Derived Imagery and Their Relation to Interpreter Performance. III. Subjective Scaling of Hard-Copy Digital Imagery.

DTIC Science & Technology

1982-02-01

OST R9UT lope ST A TeMlet r@ (of th bto.cI enteped, in e- r ’O .11 ja.Ig~pr.tt tr. t j ’) 90 SUPALEt4EPTANY NOTES It9 E Y WORDS (Conltrue ort te-PIPSO...hi extrattion performanice and .31ca’ vatw foic r di ~ t al j i ii ’-1! flitlt ldimen.iona1 scaling Can he ust-d with lim Ltd utLil ity. iii stLwdvi...Distritbut ’o, ’--’:; ited, MATTHEk J . KIUR Chief. Technioal Inforiation Division Contract F49620-80 C-0057 Life Sciences Directorate U S Air Force

Competitive antagonists discriminate between NK2 tachykinin receptor subtypes.

PubMed

Maggi, C A; Patacchini, R; Giuliani, S; Rovero, P; Dion, S; Regoli, D; Giachetti, A; Meli, A

1990-07-01

1. We have compared the ability of various tachykinins and selective tachykinin receptor agonists to induce contraction of the endothelium-denuded rabbit pulmonary artery (RPA) and hamster trachea (HT) and have estimated the affinity of some newly developed NK2 selective antagonists in the same tissues. 2. In confirmation of previous findings, experiments with the agonists indicated that NK2 receptors are the main if not the sole mediators of the response to tachykinins in both RPA and HT. No evidence for significant degradation of neurokinin A (NKA) was found in either tissue when experiments were repeated in the presence of a mixture of peptidase inhibitors (thiorphan, captopril and bestatin, 1 microM each). 3. The peptide antagonists tested were: Peptide I = [Tyr5, D-Trp6,8,9, Arg10]-NKA(4-10); Peptide II = [Tyr5, D-Trp6,8,9, Arg10]-NKA(3-10); Peptide III = Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2. The three peptides produced a concentration-dependent rightward shift of the concentration-response curve to NKA in both RPA and HT with no significant depression of the maximal response attainable. The slopes of the Schild plots were not significantly different from unity, indicating a competitive antagonism. Peptides I and II were about 100 times more potent in the RPA than in the HT, while Peptide III was about 100 times more potent in the HT than RPA. 4. The pA2 values obtained in these two tissues with the three antagonists were not significantly different when tested in the absence or presence of peptidase inhibitors, or when a selective NK2 receptor agonist, [beta Ala8]-NKA(4-10) was used instead of NKA. Similar pA2 values were obtained after 15 or 90min of incubation with the antagonists. Peptides I, II and III had no inhibitory effect on contractions produced by noradrenaline in the RPA or by carbachol in the HT. 5. Peptides I, II and III showed weak or no antagonistic activity toward the vasodilatator effect of substance P in the dog carotid artery (NK, receptor-mediated) or toward the contractile effect of neurokinin B in the rat portal vein (NK3 receptor-mediated). 6. These results provide pharmacological evidence for heterogeneity of NK2 receptors in the RPA and HT. The NK2 receptors present in these tissues are not discriminated by natural tachykinins or selective agonists, but are recognized with very different affinity by NK2 receptor antagonists.

48 CFR 35.006 - Contracting methods and contract type.

Code of Federal Regulations, 2011 CFR

2011-10-01

... indicated a high degree of probability that development is feasible and (2) the Government has determined... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.006 Contracting methods and..., performance objectives, and specifications for the work can be defined will largely determine the type of...

24 CFR 200.52 - Construction contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Construction contract. 200.52 Section 200.52 Housing and Urban Development Regulations Relating to Housing and Urban Development... Construction contract. The form of contract between the mortgagor and builder shall be as prescribed by the...

24 CFR 200.52 - Construction contract.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Construction contract. 200.52 Section 200.52 Housing and Urban Development Regulations Relating to Housing and Urban Development... Construction contract. The form of contract between the mortgagor and builder shall be as prescribed by the...

24 CFR 200.52 - Construction contract.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Construction contract. 200.52 Section 200.52 Housing and Urban Development Regulations Relating to Housing and Urban Development... Construction contract. The form of contract between the mortgagor and builder shall be as prescribed by the...

24 CFR 200.52 - Construction contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Construction contract. 200.52 Section 200.52 Housing and Urban Development Regulations Relating to Housing and Urban Development... Construction contract. The form of contract between the mortgagor and builder shall be as prescribed by the...

Lanthanide coordination polymers: Synthesis, diverse structure and luminescence properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Xue-Qin, E-mail: songxq@mail.lzjtu.cn; Lei, Yao-Kun; Wang, Xiao-Run

2014-10-15

The new semirigid exo-bidentate ligand incorporating furfurysalicylamide terminal groups, namely, 1,4-bis([(2′-furfurylaminoformyl)phenoxyl]methyl)-2,5-bismethylbenzene (L) was synthesized and used as building blocks for constructing lanthanide coordination polymers with luminescent properties. The series of lanthanide nitrate complexes have been characterized by elemental analysis, IR spectroscopy, and X-ray diffraction analysis. The semirigid ligand L, as a bridging ligand, reacts with lanthanide nitrates forming three distinct structure types: chiral noninterpenetrated two-dimensional (2D) honeycomblike (6,3) (hcb, Schläfli symbol 6{sup 3}, vertex symbol 6 6 6) topological network as type I, 1D zigzag chain as type II and 1D trapezoid ladder-like chain as type III. The structural diversitiesmore » indicate that lanthanide contraction effect played significant roles in the structural self-assembled process. The luminescent properties of Eu{sup III}, Tb{sup III} and Dy{sup III} complexes are discussed in detail. Due to the good match between the lowest triplet state of the ligand and the resonant energy level of the lanthanide ion, the lanthanide ions in Eu{sup III}, Tb{sup III} and Dy{sup III} complexes can be efficiently sensitized by the ligand. - Graphical abstract: We present herein six lanthanide coordination polymers of a new semirigid exo-bidentate ligand which not only display diverse structures but also possess strong luminescence properties. - Highlights: • We present lanthanide coordination polymers of a new semirigid exo-bidentate ligand. • The lanthanide coordination polymers exhibit diverse structures. • The luminescent properties of Tb{sup III}, Eu{sup III} and Dy{sup III} complexes are discussed in detail.« less

Recruitment of single human low-threshold motor units with increasing loads at different muscle lengths.

PubMed

McNulty, P A; Cresswell, A G

2004-06-01

We investigated the recruitment behaviour of low threshold motor units in flexor digitorum superficialis by altering two biomechanical constraints: the load against which the muscle worked and the initial muscle length. The load was increased using isotonic (low load), loaded dynamic (intermediate load) and isometric (high load) contractions in two studies. The initial muscle position reflected resting muscle length in series A, and a longer length with digit III fully extended in series B. Intramuscular EMG was recorded from 48 single motor units in 10 experiments on five healthy subjects, 21 units in series A and 27 in series B, while subjects performed ramp up, hold and ramp down contractions. Increasing the load on the muscle decreased the force, displacement and firing rate of single motor units at recruitment at shorter muscle lengths (P<0.001, dependent t-test). At longer muscle lengths this recruitment pattern was observed between loaded dynamic and isotonic contractions, but not between isometric and loaded dynamic contractions. Thus, the recruitment properties of single motor units in human flexor digitorum superficialis are sensitive to changes in both imposed external loads and the initial length of the muscle.

Wound healing activity of Sida cordifolia Linn. in rats

PubMed Central

Pawar, Rajesh S.; Chaurasiya, Pradeep K.; Rajak, Harish; Singour, Pradeep K.; Toppo, Fedelic Ashish; Jain, Ankit

2013-01-01

Introduction: The present study provides a scientific evaluation for the wound healing potential of ethanolic (EtOH) extract of Sida cordifolia Linn. (SCL) plant. Materials and Methods: Excision, incision and burn wounds were inflicted upon three groups of six rats each. Group I was assigned as control (ointment base). Group II was treated with 10% EtOH extract ointment. Group III was treated with standard silver sulfadiazine (0.01%) cream. The parameters observed were percentage of wound contraction, epithelialization period, hydroxyproline content, tensile strength including histopathological studies. Result: It was noted that the effect produced by the ethanolic extract of SCL ointment showed significant (P < 0.01) healing in all wound models when compared with the control group. All parameters such as wound contraction, epithelialization period, hydroxyproline content, tensile strength and histopathological studies showed significant (P < 0.01) changes when compared with the control. Conclusion: The ethanolic extract ointment of SCL effectively stimulates wound contraction; increases tensile strength of excision, incision and burn wounds. PMID:24130382

24 CFR 206.133 - Termination of insurance contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Termination of insurance contract. 206.133 Section 206.133 Housing and Urban Development Regulations Relating to Housing and Urban... Contract § 206.133 Termination of insurance contract. (a) Payment of the mortgage. The contract of...

Treatments for achalasia in 2017: how to choose among them.

PubMed

Kahrilas, Peter J; Pandolfino, John E

2017-07-01

To review recent advances in achalasia diagnostics and therapeutics. The cardinal feature of achalasia, impaired lower esophageal sphincter (LES) relaxation, can occur in association with varied patterns of esophageal contractility. The Chicago Classification distinguishes among these as follows: without contractility (type I), with panesophageal pressurization (type II), with premature (spastic) distal esophageal contractions (type III), or even with preserved peristalsis [esophagogastric junction (EGJ) outlet obstruction]. Physiological testing also reveals achalasia-like syndromes that also benefit from achalasia therapies. Coincident with this has been the development of peroral endoscopic myotomy (POEM), an endoscopic technique for performing an esophageal myotomy. Hence, the option now exists to either selectively ablate the LES (pneumatic dilation, laparoscopic Heller myotomy, or POEM) or to ablate the sphincter and create a myotomy along some or the entire adjacent smooth muscle esophagus (POEM). Each achalasia syndrome has unique treatment considerations; type II achalasia responds well to all therapies, whereas type III responds best to POEM. Emerging data support the concept that optimal management of achalasia is phenotype-specific, guided by high-resolution manometry, and, in some instance, functional luminal imaging probe studies. This opinion article reviews the varied characteristic and treatment considerations of achalasia syndromes as currently understood.

Speciation and Attenuation of Arsenic and Selenium at Coal Combustion By-Product Management Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Ladwig; B. Hensel; D. Wallschlager

2005-10-18

Following completion of contracting activities, sites were identified for the field leachate characterization study. Sampling and Analyses Plans (SAPs) and Site Access Agreements (SAAs) were developed for each site. A total of ten sites were sampled during this reporting period. Among the trace constituents, boron, silicon, and strontium were present in highest concentrations, with median values above 1 mg/L (1,000 {micro}g/L). Work on the first of three sites for the detailed arsenic and selenium adsorption studies began in 2002, prior to completion of the final DOE award. Kd values ranged from 100 to 12,000 L/kg for arsenic (V), 15 tomore » 160 L.kg for As(III), and 5 to 25 L/kg for Se(VI).« less

48 CFR 46.307 - Fixed-price research and development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.307 Fixed-price research and development... Development—Fixed-Price, in solicitations and contracts for research and development when (1) the primary... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Fixed-price research and...

7 CFR Appendix A to Subpart C of... - Model Form of Loan Contract for Electric Distribution Borrowers

Code of Federal Regulations, 2012 CFR

2012-01-01

... financial ratios: (i) TIER of 1.25; (ii) Operating TIER of 1.1; (iii) DSC of 1.25; and Operating DSC of 1.1... Coverage Ratios Requirements. Section 5.5. Depreciation Rates. Section 5.6. Property Maintenance. Section 5.7. Financial Books. Section 5.8. Rights of Inspection. Section 5.9. Area Coverage. Section 5.10...

7 CFR Appendix A to Subpart C of... - Model Form of Loan Contract for Electric Distribution Borrowers

Code of Federal Regulations, 2013 CFR

2013-01-01

... financial ratios: (i) TIER of 1.25; (ii) Operating TIER of 1.1; (iii) DSC of 1.25; and Operating DSC of 1.1... Coverage Ratios Requirements. Section 5.5. Depreciation Rates. Section 5.6. Property Maintenance. Section 5.7. Financial Books. Section 5.8. Rights of Inspection. Section 5.9. Area Coverage. Section 5.10...

7 CFR Appendix A to Subpart C of... - Model Form of Loan Contract for Electric Distribution Borrowers

Code of Federal Regulations, 2011 CFR

2011-01-01

... financial ratios: (i) TIER of 1.25; (ii) Operating TIER of 1.1; (iii) DSC of 1.25; and Operating DSC of 1.1... Coverage Ratios Requirements. Section 5.5. Depreciation Rates. Section 5.6. Property Maintenance. Section 5.7. Financial Books. Section 5.8. Rights of Inspection. Section 5.9. Area Coverage. Section 5.10...

7 CFR Appendix A to Subpart C of... - Model Form of Loan Contract for Electric Distribution Borrowers

Code of Federal Regulations, 2014 CFR

2014-01-01

... financial ratios: (i) TIER of 1.25; (ii) Operating TIER of 1.1; (iii) DSC of 1.25; and Operating DSC of 1.1... Coverage Ratios Requirements. Section 5.5. Depreciation Rates. Section 5.6. Property Maintenance. Section 5.7. Financial Books. Section 5.8. Rights of Inspection. Section 5.9. Area Coverage. Section 5.10...

Examination of Psychological Type and Preferred Negotiation Tactics and Strategies of Contract Negotiators

DTIC Science & Technology

1992-09-01

Auxiliary Process .................. 23 iii Page The Myers-Briggs Type Indicator ....................... 24 The Relationship of Personality Type and...negotiation tactics and/or strategies. Major Charan Johnstone (1986) studied the relationship of psychological type as measured by the Myers-Briggs Type...1986:118). Determining psychological type for both government and industry negotiators, and the relationship to negotiation tactics and strategies may

Affordable Emerging Computer Hardware for Neuromorphic Computing Applications

DTIC Science & Technology

2011-09-01

DATES COVERED (From - To) 4 . TITLE AND SUBTITLE AFFORDABLE EMERGING COMPUTER HARDWARE FOR NEUROMORPHIC COMPUTING APPLICATIONS 5a. CONTRACT NUMBER...speedup over software [3, 4 ]. 3 Table 1 shows a comparison of the computing performance, communication performance, power consumption...time is probably 5 frames per second, corresponding to 5 saccades. III. RESULTS AND DISCUSSION The use of IBM Cell-BE technology (Sony PlayStation

Effective Leadership: Perceptions of Newcomers and Old Timers in the Navy

DTIC Science & Technology

1974-10-01

and subordinate performance and satisfaction as the dependent variable criteria. Korman divides his results according to the source of the criteria...generalization. Several theorists have postulated that leaders and sub- ordinates should have shared expectations if performance and satisfaction ...Technical Report • PERFORMING ORG. REPORT NUMBER 7. AUTHORr«; Stanley M. Nealey George C. Thornton, III I. CONTRACT OR GRANT NUMBERC«) N00014-73

Teaching resources. The Sherlock Holmes lab: investigations in neurophysiology.

PubMed

Adler, Elizabeth M; Schwartz, Paul J

2006-05-09

This Teaching Resource describes a research project that can be used in an advanced undergraduate course in neurobiology that covers basic electrophysiology and synaptic transmission. A thought experiment is provided that can be used to assess student understanding of (i) the scientific method, (ii) the process whereby nerve stimulation leads to muscle contraction, and (iii) the use of pharmacological agents to analyze a physiological system.

Peripheral apelin-13 administration inhibits gastrointestinal motor functions in rats: The role of cholecystokinin through CCK1 receptor-mediated pathway.

PubMed

Bülbül, Mehmet; Sinen, Osman; Birsen, İlknur; Nimet İzgüt-Uysal, V

2017-06-01

Apelin is the endogenous ligand of the G protein-coupled receptor APJ. The APJ receptor is widely expressed in gastrointestinal (GI) tissues including stomach and small intestine. Apelin administration was shown to induce the release of cholecystokinin (CCK) which is a well-known alimentary hormone with its inhibitory actions on GI motor functions through CCK 1 receptors on vagal afferent fibers. We investigated whether; (i) peripherally injected apelin-13 alters GI motor functions, (ii) apelin-induced changes are mediated by APJ receptor or CCK 1 receptor and (iii) vagal afferents are involved in inhibitory effects of apelin. Solid gastric emptying (GE) and colon transit (CT) were measured, whereas duodenal phase III-like contractions were recorded in rats administered with apelin-13 (300μg/kg, ip). CCK 1 receptor antagonist lorglumide (10mg/kg, ip) or APJ receptor antagonist F13A (300μg/kg, ip) was administered 30min prior to the apelin-13 injections. Vagal afferent denervation was achieved by systemic administration of vanilloid receptor agonist capsaicin (125mg/kg, sc). Apelin-13 administration significantly (p<0.01) increased the CCK level in portal venous plasma samples. Compared with vehicle-treated rats, apelin-13 significantly delayed both GE (p<0.001) and CT (p<0.01). Pretreatment of lorglumide or F13A completely abolished the apelin-13-induced inhibitory effects on GE and CT, moreover, apelin-13 was found ineffective in rats underwent afferent denervation. F13A administration alone significantly accelerated the basal CT. Apelin-13 noticeably disturbed the duodenal fasting motor pattern by impairing phase III-like contractions while increasing the amplitudes of phase II contractions which were prevented by pretreatment of lorglumide and capsaicin. Compared with vehicle-treated rats, lorglumide and capsaicin significantly (p<0.05) reduced the apelin-13-induced increases in phase II motility index. Peripherally administered apelin-13 inhibits GI motor functions through CCK-dependent pathway which appears to be mediated by CCK 1 receptors on vagal afferents. Peripheral apelin might contribute to the motility changes occurred in postprandial period. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Comparison of anorectal pressure after procedure for prolapse and hemorrhoids versus Doppler-guided hemorrhoidal artery ligation for grade III hemorrhoids].

PubMed

Dong, Xiao-ni; Tang, Ying-chun

2013-12-01

To compare the long-term anorectal manometry of patients with grade III hemorrhoids treated by procedure for prolapse and hemorrhoids (PPH) or Doppler-guided hemorrhoidal artery ligation (DGHAL). A total of 114 patients with grade III hemorrhoids in our department in 2010 were prospectively enrolled, and divided into PPH group (63 cases) and DGHAL group (51 cases) according to patient preference. Patients received anorectal pressure examination 2, 6, 12, 18 months after operation, including rectal resting pressure, anal resting pressure, maximal anal contractive pressure and length of high-pressure band. Anorectal manometries between two procedure groups were compared. In every time point of follow-up, as compared to PPH group, DGHAL group presented higher anal resting pressure[postoperative 2 months: (56.2±2.6) mmHg vs. (43.2±3.1) mmHg, postoperative 6 months: (55.2±2.1) mmHg vs. (45.1±2.5) mmHg, postoperative 12 months: (53.2±3.0) mmHg vs. (40.2±3.2) mmHg, postoperative 18 months: (55.3±2.6) mmHg vs. (43.2±2.5) mmHg, all P<0.01], and longer length of high-pressure band [postoperative 2 months: (3.45±0.14) cm vs. (2.95±0.22) cm, postoperative 6 months: (3.46±0.12) cm vs. (2.94±0.26) cm, postoperative 12 months: (3.45±0.12) cm vs. (3.01±0.21) cm, postoperative 18 months: (3.56±0.12) cm vs. (3.02±0.23) cm, all P<0.01]. While no significant differences of maximal anal contractive pressure and rectal resting pressure were found between the two groups. Both PPH and DGHAL are safe procedures and have similar efficacy in the treatment of grade III hemorrhoids, while DGHALpossesses better efficacy in the time of anal function recovery and the maintenance of anal function.

Renewable Energy Contract Development Best Practices

EPA Pesticide Factsheets

The Toolbox for Renewable Energy Project Development's Renewable Energy Contract Development Best Practices page provides an overview of the Request for Proposal (RFP) process as well as resources, such as contract templates.

The Functional Lumen Imaging Probe Detects Esophageal Contractility Not Observed With Manometry in Patients With Achalasia.

PubMed

Carlson, Dustin A; Lin, Zhiyue; Kahrilas, Peter J; Sternbach, Joel; Donnan, Erica N; Friesen, Laurel; Listernick, Zoe; Mogni, Benjamin; Pandolfino, John E

2015-12-01

The functional lumen imaging probe (FLIP) could improve the characterization of achalasia subtypes by detecting nonocclusive esophageal contractions not observed with standard manometry. We aimed to evaluate esophageal contractions during volumetric distention in patients with achalasia using FLIP topography. Fifty-one treatment-naive patients with achalasia, defined and subclassified by high-resolution esophageal pressure topography, and 10 asymptomatic individuals (controls) were evaluated with the FLIP during endoscopy. During stepwise distension, simultaneous intrabag pressures and 16 channels of cross-sectional areas were measured; data were exported to software that generated FLIP topography plots. Esophageal contractility was identified by noting periods of reduced luminal diameter. Esophageal contractions were characterized further by propagation direction, repetitiveness, and based on whether they were occluding or nonoccluding. Esophageal contractility was detected in all 10 controls: 8 of 10 had repetitive antegrade contractions and 9 of 10 had occluding contractions. Contractility was detected in 27% (4 of 15) of patients with type I achalasia and in 65% (18 of 26, including 9 with occluding contractions) of patients with type II achalasia. Contractility was detected in all 10 patients with type III achalasia; 8 of these patients had a pattern of contractility that was not observed in controls (repetitive retrograde contractions). Esophageal contractility not observed with manometry can be detected in patients with achalasia using FLIP topography. The presence and patterns of contractility detected with FLIP topography may represent variations in pathophysiology, such as mechanisms of panesophageal pressurization in patients with type II achalasia. These findings could have implications for additional subclassification to supplement prediction of the achalasia disease course. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

The Functional Lumen Imaging Probe Detects Esophageal Contractility not Observed with Manometry in Patients with Achalasia

PubMed Central

Carlson, Dustin A.; Lin, Zhiyue; Kahrilas, Peter J.; Sternbach, Joel; Donnan, Erica N.; Friesen, Laurel; Listernick, Zoe; Mogni, Benjamin; Pandolfino, John E.

2015-01-01

Background & Aims The functional lumen imaging probe (FLIP) could improve characterization of achalasia subtypes by detecting non-occlusive esophageal contractions not observed with standard manometry. We aimed to evaluate for esophageal contractions during volumetric distention in patients with achalasia using FLIP topography. Methods Fifty one treatment-naïve patients with achalasia, defined and sub-classified by high-resolution esophageal pressure topography, and 10 asymptomatic individuals (controls) were evaluated with the FLIP during endoscopy. During stepwise distension, simultaneous intra-bag pressures and 16 channels of cross-sectional areas were measured; data were exported to software that generated FLIP topography plots. Esophageal contractility was identified by noting periods of reduced luminal diameter. Esophageal contractions were further characterized by propagation direction, repetitiveness, and based on whether they were occluding or non-occluding. Results Esophageal contractility was detected in all 10 controls: 8/10 had repetitive, antegrade, contractions and 9/10 had occluding contractions. Contractility was detected in 27% (4/15) of patients with type I achalasia and 65% (18/26, including 9 with occluding contractions) of patients with type II achalasia. Contractility was detected in all 10 patients with type III achalasia; 8 of these patients had a pattern of contractility not observed in controls (repetitive, retrograde contractions). Conclusions Esophageal contractility not observed with manometry can be detected in patients with achalasia using FLIP topography. The presence and patterns of contractility detected with FLIP topography may represent variations in pathophysiology, such as mechanisms of pan-esophageal pressurization in patients with type II achalasia. These findings could have implications for additional sub-classification to supplement prediction of the achalasia disease course. PMID:26278501

Activation-dependent descending reflex evacuation motority of anal canal in rat model.

PubMed

Radomirov, Radomir; Negrev, Negrin; Itzev, Dimitar Evlogiev; Stavreva, Galya

2010-12-01

The evacuative motor responses of the anal canal and recto-anal reflexes during defecation were studied in an isolated rat recto-anal model preparation using (i) partitioned organ bath, (ii) electrical stimulation, (iii) balloon distension and (iv) morphological techniques. Electrical field stimulation applied to the anal canal or to the distal part of the rectum elicited tetrodotoxin (10(-7) M)-sensitive frequency-dependent local or descending contractions of the anal canal and the local responses were bigger in amplitude (14.9 ± 1.35 mN) than the descending contractions (5.3 ± 0.7 mN at frequency of 5 Hz, p < 0.05). The balloon-induced distension of the distal rectum evoked descending responses of the anal canal consisting of a short contraction (1.50 ± 0.18 mN) followed by deep relaxation (3.12 ± 0.34 mN). In the presence of atropine (3 x 10(-7) M) the electrically-elicited (5 Hz) local or descending contractions of the anal canal were suppressed and a relaxation revealed. The initial contraction component of the distension-induced response was decreased while the relaxation was not changed. During atropine treatment, spantide (10(-7) M) lowered even more the contractile component of the anal canal response. NG-nitro-L-arginine (5 x 10(-4) M) enhanced the contraction, prevented the atropine-dependent relaxation of the electrically-elicited response and inhibited the distension-induced relaxation. L-Arginine (5 x 10(-4) M) suppressed the contraction and extended the relaxation. ChAT-, substance P- and NADPH-diaphorase-positive perikarya and nerve fibers were observed in myenteric ganglia of the anal canal. The results suggest activation-dependent descending reflex motority of the anal canal involving electrical stimulation-displayed cholinergic and tachykininergic and distension manifested nitrergic neuro-muscular communications.

Joint Implications for Contracted Logistics

DTIC Science & Technology

2007-03-30

authority with the host nation country and policy on using UCMJ for contracted personnel. As tailored theater policies are developed and contracting...responsibility, this paper recommends better joint training, leader development and joint enablers for contracting operations. JOINT...U.S. Joint Forces Command (JFCOM) are analyzing Congressional and DOD policy to develop procedures and force structure to support contractor

48 CFR 11.503 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., Liquidated Damages—Supplies, Services, or Research and Development, in fixed-price solicitations and contracts for supplies, services, or research and development when the contracting officer determines that...—Construction, in solicitations and contracts for construction, other than cost-plus-fixed-fee, when the...

Endothelin induces two types of contractions of rat uterus: phasic contractions by way of voltage-dependent calcium channels and developing contractions through a second type of calcium channels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kozuka, M.; Ito, T.; Hirose, S.

1989-02-28

Effects of endothelin on nonvascular smooth muscle have been examined using rat uterine horns and two modes of endothelin action have been revealed. Endothelin (0.3 nM) caused rhythmic contractions of isolated uterus in the presence of extracellular calcium. The rhythmic contractions were completely inhibited by calcium channel antagonists. These characteristics of endothelin-induced contractions were very similar to those induced by oxytocin. Binding assays using /sup 125/I-endothelin showed that endothelin and the calcium channel blockers did not compete for the binding sites. However, endothelin was unique in that it caused, in addition to rhythmic contractions, a slowly developing monophasic contraction thatmore » was insensitive to calcium channel blockers. This developing contraction became dominant at higher concentrations of endothelin and was also calcium dependent.« less

Enhanced chemical weapon warning via sensor fusion

NASA Astrophysics Data System (ADS)

Flaherty, Michael; Pritchett, Daniel; Cothren, Brian; Schwaiger, James

2011-05-01

Torch Technologies Inc., is actively involved in chemical sensor networking and data fusion via multi-year efforts with Dugway Proving Ground (DPG) and the Defense Threat Reduction Agency (DTRA). The objective of these efforts is to develop innovative concepts and advanced algorithms that enhance our national Chemical Warfare (CW) test and warning capabilities via the fusion of traditional and non-traditional CW sensor data. Under Phase I, II, and III Small Business Innovative Research (SBIR) contracts with DPG, Torch developed the Advanced Chemical Release Evaluation System (ACRES) software to support non real-time CW sensor data fusion. Under Phase I and II SBIRs with DTRA in conjunction with the Edgewood Chemical Biological Center (ECBC), Torch is using the DPG ACRES CW sensor data fuser as a framework from which to develop the Cloud state Estimation in a Networked Sensor Environment (CENSE) data fusion system. Torch is currently developing CENSE to implement and test innovative real-time sensor network based data fusion concepts using CW and non-CW ancillary sensor data to improve CW warning and detection in tactical scenarios.

Formation, expansion, and interconversion of metallarings in a sulfur-bridged Au(I) Co(III) coordination system.

PubMed

Oji, Katsuya; Igashira-Kamiyama, Asako; Yoshinari, Nobuto; Konno, Takumi

2014-02-10

A novel Au(I) Co(III) coordination system that is derived from the newly prepared [Co(D-nmp)2 ](-) (1(-) ; D-nmp=N-methyl-D-penicillaminate) and a gold(I) precursor Au(I) is reported. Complex 1(-) acts as a sulfur-donating metallaligand and reacts with the gold(I) precursor to give [Au2 Co2 (D-nmp)4 ] (2), which has an eight-membered Au(I) 2 Co(III) 2 metallaring. Treatment of 2 with [Au2 (dppe)2 ](2+) (dppe=1,2-bis(diphenylphosphino)ethane) leads to the formation of [Au4 Co2 (dppe)2 (D-nmp)4 ](2+) (3(2+) ), which consists of an 18-membered Au(I) 4 Co(III) 2 metallaring that accommodates a tetrahedral anion (BF4 (-) , ClO4 (-) , ReO4 (-) ). In solution, the metallaring structure of 3(2+) is readily interconvertible with the nine-membered Au(I) 2 Co(III) metallaring structure of [Au2 Co(dppe)(D-nmp)2 ](+) (4(+) ); this process depends on external factors, such as solvent, concentration, and nature of the counteranion. These results reveal the lability of the AuS and AuP bonds, which is essential for metallaring expansion and contraction. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

High speed electrostatic photomultiplier tube for the 1.06 micrometer wavelength. Cup and slat dynode chain combined with flat cathode and coax output produces 0.25 nsec rise time

NASA Technical Reports Server (NTRS)

Sparks, S. D.

1973-01-01

The Varian cup and slat dynode chain was modified to have a flat cathode. These modifications were incorporated in an all-electrostatic photomultiplier tube having a rise time of 0.25 n sec. The tube delivered under the contract had a flat S-20 opaque cathode with a useful diameter of 5 mm. The design of the tube is such that a III to V cathode support is mounted in place of the existing cathode substrate. This cathode support is designed to accept a transferred III to V cathode and maintain the cathode surface in the same position as the S-20 photocathode.

A profile of PMS salaried GP contracts and their impact on recruitment.

PubMed

Williams, J; Petchey, R; Gosden, T; Leese, B; Sibbald, B

2001-06-01

Personal medical services (PMS) pilot sites aim to use salaried GP schemes to improve GP recruitment and retention and enhance the quality of service provision, particularly in underserved areas. Our objectives were to (i) compare the work incentives of salaried compared with standard GP contracts; (ii) assess recruitment success to salaried posts; and (iii) describe the types of GPs attracted to these new posts. All first wave PMS pilot sites with salaried GP posts known to be 'live' in October 1998 were included in the analysis of employment contracts and job descriptions. Information on recruitment was obtained by a questionnaire survey of PMS sites that were intending to recruit a salaried GP. The mean full-time equivalent salary was 43,674 pounds sterling with additional benefits in terms of sick leave, maternity leave and paid expenses. Eighty-nine percent of posts were eligible for the NHS pension scheme. Posts were mainly full time (40.8 hours per week). GPs were responsible for providing services equivalent in scope to general medical services. One-fifth of contracts freed GPs from out-of-hours responsibility and most freed them from practice management. Forty-three of the pilot sites actively recruited to fill 63 salaried posts, which involved a total of 51 recruitment 'rounds', with some pilots advertising more than once. There were 291 applications. The median number of applicants per post was three and the median time to recruitment was 6 weeks. Eighty-five percent of sites were satisfied with the quality of their applicants and 64% with the quantity. Eighty-five percent of applicants previously had been working in general practice, most in locum or salaried posts. Applicants tended to be young and male. Sixty posts were filled. Salaried contracts offer positive incentives to recruitment in terms of reduced hours of work and freedom from administrative responsibility. Recruitment success was similar to that achieved by inner city practices generally. This modest achievement might be enhanced by the addition of professional development schemes and increased flexible/part-time working.

Positive inotropic effects of RP 62719, a new pure class III antiarrhythmic agent, on guinea pig myocardium.

PubMed

Beregi, J P; Escande, D; Coudray, N; Mery, P; Mestre, M; Chemla, D; Lecarpentier, Y

1992-12-01

The mechanical effects of RP 62719 [(-)1-[-2-(3,4-dihydro-2H-1- benzopyran-4-yl)ethyl]-4-(3,4-dimethoxyphenyl)-piperidine] were tested in vitro on guinea pig left ventricular papillary muscle. RP 62719 is a novel pure class III antiarrhythmic agent known to prolong the cardiac action potential duration by selectively blocking the inward rectifying K+ current. Mechanical parameters were determined from contraction and relaxation phases under isotonic and isometric conditions. At a concentration of 0.02 microM, RP 62719 did not produce significant effects on inotropy or lusitropy. At 0.2 and 2 microM, the drug improved contraction under both heavy and low loading conditions, as evidenced by a 30% increase in maximum unloaded shortening velocity (Vmax, P < .001), peak amplitude of shortening (delta L, P < .001), peak isometric active force normalized per cross-sectional area (AF/s, P < .001) and positive peak of the force derivative per mm2 (+dF/s, P < .001). At the same concentrations, positive lusitropic effects were evidenced by an increase in maximum lengthening velocity (maxVr) and negative peak of force derivative per mm2 (-dF/s, P < .001). At a higher concentration (20 microM), effects of RP 62719 on inotropy and lusitropy were less marked, thus accounting for the bell-shaped form of the dose-response curve. An increase in the extracellular Ca++ concentration from 2.5 to 3.75 mM improved inotropy to a similar extent (+30-50%) as did 2 microM RP 62719. However, lusitropy and mechanical coupling between contraction and relaxation were not modified in the same proportion under RP 62719 and under 3.75 mM Ca++.(ABSTRACT TRUNCATED AT 250 WORDS)

Myoelectric manifestations of jaw elevator muscle fatigue and recovery in healthy and TMD subjects.

PubMed

Castroflorio, T; Falla, D; Tartaglia, G M; Sforza, C; Deregibus, A

2012-09-01

The effects of muscle pain and fatigue on the control of jaw elevator muscles are not well known. Furthermore, the myoelectric manifestations of fatigue and recovery from fatigue in the masticatory muscles are not reported in literature. The main aims of this study were (i) to evaluate the possible use of surface electromyography (sEMG) as an objective measure of fatigue of the jaw elevator muscles, (ii) to compare the myoelectric manifestations of fatigue in the temporalis anterior and masseter muscles bilaterally, (iii) to assess recovery of the investigated muscles after an endurance test and (iv) to compare fatigue and recovery of the jaw elevator muscles in healthy subjects and patients with muscle-related temporomandibular disorders (TMD). The study was performed on twenty healthy volunteers and eighteen patients with muscle-related TMD. An intra-oral compressive-force sensor was used to measure the voluntary contraction forces close to the intercuspal position and to provide visual feedback of submaximal forces to the subject. Surface EMG signals were recorded with linear electrode arrays during isometric contractions at 20%, 40%, 60% and 80% of the maximum voluntary contraction force, during an endurance test and during the recovery phase. The results showed that (i) the slope of the mean power spectral frequency (MNF) and the initial average rectified value (ARV) could be used to monitor fatigue of the jaw elevators, (ii) the temporalis anterior and masseter muscle show the same myoelectric manifestations of fatigue and recovery and (iii) the initial values of MNF and ARV were lower in patients with muscle-related TMD. The assessment of myoelectric manifestations of fatigue in the masticatory muscles may assist in the clinical assessment of TMDs. © 2012 Blackwell Publishing Ltd.

Star Pattern Recognition and Spacecraft Attitude Determination.

DTIC Science & Technology

1978-10-01

Mr. Lawrence D. Ziems, Computer Programuer Prepared For: ,ti U.S. Army Engineer Topographic Laboratories Fort Belvoir, Virginia 22060 Contract No...CONTENTS PORIVAD i SIMARY iii 1.0 Introduction and System Overviev 1 2.0 Reference Frames Geometry and Kinematics 9 3.0 Star Pattern Recognition/Attitude...Laboratories (USAETL). The authors appreciate the capable guidance of Mr. L. A. Gambino, Director of the Computer Science Laboratory (USAETL), who served as

Department of Defense Finance and Accounting Service FY 1996/1997 Biennial Budget Estimates, February 1995.

DTIC Science & Technology

1995-02-01

Descriptive Summary 2 FIP Resources and Indefinite Delivery - Quantity Contracts 3 Central Design Activity Summary 4 Accesion For NTIS CRA&IDTIC TAB...interface with financial systems should be integrated into the standard architecture of the Military Departments iii to ensure maximum cost...provided to support and maintain the DFAS enterprise local area network initiative to establish a standardized architecture for office automation and

Matthew Jones House: Recommendations for Treatment

DTIC Science & Technology

2016-04-01

strongly recommend that a structural engineer be contracted to provide in depth analysis and monitoring. The decay of the historic timber top plates...of the structure . This report summarizes the research and findings by the NCPTT. It also includes an engineer’s report and other supplemental in...NEEDED. DO NOT RETURN IT TO THE ORIGINATOR. ERDC/CERL CR-16-1 iii Foreword After identifying a variety of structural issues with the Matthew Jones

77 FR 26810 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... Amend Schedule 502 of the ICC Rules To Update the Contract Reference Obligation ISINs Associated With... ICC. ICC filed the proposal pursuant to Section 19(b)(3)(A)(iii) of the Act,\\3\\ and Rule 19b-4(f)(3... publishing this notice to solicit comments on the rule change from interested parties. \\1\\ 15 U.S.C. 78s(b)(1...

Career Planning: Individual and Organizational Perspectives.

DTIC Science & Technology

1981-07-01

1978; Louis, 1980a). The substantial impact of the transition period and the increasingly prevalent occurrence of major worklife changes involving...Individual and Organization~al "P CO/f RED Perspectivesi /Tcnia_ 00WE 7. AUHOR~s III CONTRACT OR GRANT NUMSCR(s) James K.Arima (Ed.) 9. PERFORMING ...participants and their superb contributions. Many thanks are due to Karen Brown for typing the manuscript and performing the many chores incidental to its

Blast Injury: Translating Research Into Operational Medicine (Preprint)

DTIC Science & Technology

2008-05-20

i Blast Injury: Translating Research into Operational Medicine Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for...SUBTITLE Blast Injury: Translating Research Into Operational Medicine 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...Z39-18 iii Blast Injury: Translating Research into Operational Medicine Preprint BI-QP-JHS-CH10 Borden Institute This chapter was originally

Incorporation of Indigenous Forces in Major Theater War: Advantages, Risks and Considerations

DTIC Science & Technology

2004-05-03

USAWC STRATEGY RESEARCH PROJECT INCORPORATION OF INDIGENOUS FORCES IN MAJOR THEATER WAR: ADVANTAGES , RISKS AND CONSIDERATIONS by Ms. Priscilla... Advantages , Risks and Considerations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Priscilla Sellers 5d. PROJECT NUMBER...Std Z39-18 ii iii ABSTRACT AUTHOR: Priscilla Sellers TITLE: Incorporation of Indigenous Forces in Major Theater War: Advantages , Risks and

48 CFR 716.406 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clauses. 716.406 Section 716.406 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost Reimbursement Contracts 716.406 Contract clauses. The...

48 CFR 716.406 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 716.406 Section 716.406 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost Reimbursement Contracts 716.406 Contract clauses. The...

24 CFR 965.308 - Energy performance contracts.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Energy performance contracts. 965... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Energy Audits and Energy Conservation Measures § 965.308 Energy performance contracts. (a) Method of procurement. Energy performance contracting...

24 CFR 965.308 - Energy performance contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Energy performance contracts. 965... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Energy Audits and Energy Conservation Measures § 965.308 Energy performance contracts. (a) Method of procurement. Energy performance contracting...

24 CFR 965.308 - Energy performance contracts.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Energy performance contracts. 965... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Energy Audits and Energy Conservation Measures § 965.308 Energy performance contracts. (a) Method of procurement. Energy performance contracting...

24 CFR 965.308 - Energy performance contracts.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Energy performance contracts. 965... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Energy Audits and Energy Conservation Measures § 965.308 Energy performance contracts. (a) Method of procurement. Energy performance contracting...

24 CFR 965.308 - Energy performance contracts.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Energy performance contracts. 965... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Energy Audits and Energy Conservation Measures § 965.308 Energy performance contracts. (a) Method of procurement. Energy performance contracting...

Contracting out of health services in developing countries.

PubMed

McPake, B; Banda, E E

1994-03-01

Contracting out is emerging as a common policy issue in a number of developing countries. The theoretical case for contracting out suggests many advantages in combining public finance with private provision. However, practical difficulties such as those of ensuring that competition takes place between potential contractors, that competition leads to efficiency and that contracts and the process of contracting are effectively managed, suggest that such advantages may not always be realized. Most countries are likely only to contemplate restricted contracting of small-scale non-clinical services in the short term. Prerequisites of more extensive models appear to be the development of information systems and human resources to that end. Some urban areas of larger countries may have the existing preconditions for more successful large-scale contracting.

A New Slow Releasing, H2S Generating Compound, GYY4137 Relaxes Spontaneous and Oxytocin-Stimulated Contractions of Human and Rat Pregnant Myometrium

PubMed Central

Robinson, Hayley; Wray, Susan

2012-01-01

Better tocolytics are required to help prevent preterm labour. The gaseotransmitter Hydrogen sulphide (H2S) has been shown to reduce myometrial contractility and thus is of potential interest. However previous studies used NaHS, which is toxic and releases H2S as a non-physiological bolus and thus alternative H2S donors are sought. GYY4137 has been developed to slowly release H2S and hence better reflect endogenous physiological release. We have examined its effects on spontaneous and oxytocin-stimulated contractility and compared them to NaHS, in human and rat myometrium, throughout gestation. The effects on contractility in response to GYY4137 (1 nM–1 mM) and NaHS (1 mM) were examined on myometrial strips from, biopsies of women undergoing elective caesarean section or hysterectomy, and from non-pregnant, 14, 18, 22 day (term) gestation or labouring rats. In pregnant rat and human myometrium dose-dependent and significant decreases in spontaneous contractions were seen with increasing concentrations of GYY4137, which also reduced underlying Ca transients. GYY4137 and NaHS significantly reduced oxytocin-stimulated and high-K depolarised contractions as well as spontaneous activity. Their inhibitory effects increased as gestation advanced, but were abruptly reversed in labour. Glibenclamide, an inhibitor of ATP-sensitive potassium (KATP) channels, abolished the inhibitory effect of GYY4137. These data suggest (i) H2S contributes to uterine quiescence from mid-gestation until labor, (ii) that H2S affects L-type calcium channels and KATP channels reducing Ca entry and thereby myometrial contractions, (iii) add to the evidence that H2S plays a physiological role in relaxing myometrium, and thus (iv) H2S is an attractive target for therapeutic manipulation of human myometrial contractility. PMID:23029460

Characterization of the solid low level mixed waste inventory for the solid waste thermal treatment activity - III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Place, B.G., Westinghouse Hanford

1996-09-24

The existing thermally treatable, radioactive mixed waste inventory is characterized to support implementation of the commercial, 1214 thermal treatment contract. The existing thermally treatable waste inventory has been identified using a decision matrix developed by Josephson et al. (1996). Similar to earlier waste characterization reports (Place 1993 and 1994), hazardous materials, radionuclides, physical properties, and waste container data are statistically analyzed. In addition, the waste inventory data is analyzed to correlate waste constituent data that are important to the implementation of the commercial thermal treatment contract for obtaining permits and for process design. The specific waste parameters, which were analyzed,more » include the following: ``dose equivalent`` curie content, polychlorinated biphenyl (PCB) content, identification of containers with PA-related mobile radionuclides (14C, 12 79Se, 99Tc, and U isotopes), tritium content, debris and non-debris content, container free liquid content, fissile isotope content, identification of dangerous waste codes, asbestos containers, high mercury containers, beryllium dust containers, lead containers, overall waste quantities, analysis of container types, and an estimate of the waste compositional split based on the thermal treatment contractor`s proposed process. A qualitative description of the thermally treatable mixed waste inventory is also provided.« less

48 CFR 216.403-1 - Fixed-price incentive (firm target) contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (firm target) contracts. 216.403-1 Section 216.403-1 Federal Acquisition Regulations System DEFENSE... CONTRACTS Incentive Contracts 216.403-1 Fixed-price incentive (firm target) contracts. (b) Application. (1... target) contracts, especially for acquisitions moving from development to production. (2) The contracting...

48 CFR 1335.006 - Contracting methods and contract type.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1335.006 Contracting methods and... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contracting methods and... research services under the contract might involve the use of human subjects. The provision is mandatory...

The preoperative manometric pattern predicts the outcome of surgical treatment for esophageal achalasia.

PubMed

Salvador, Renato; Costantini, Mario; Zaninotto, Giovanni; Morbin, Tiziana; Rizzetto, Christian; Zanatta, Lisa; Ceolin, Martina; Finotti, Elena; Nicoletti, Loredana; Da Dalt, Gianfranco; Cavallin, Francesco; Ancona, Ermanno

2010-11-01

A new manometric classification of esophageal achalasia has recently been proposed that also suggests a correlation with the final outcome of treatment. The aim of this study was to investigate this hypothesis in a large group of achalasia patients undergoing laparoscopic Heller-Dor myotomy. We evaluated 246 consecutive achalasia patients who underwent surgery as their first treatment from 2001 to 2009. Patients with sigmoid-shaped esophagus were excluded. Symptoms were scored and barium swallow X-ray, endoscopy, and esophageal manometry were performed before and again at 6 months after surgery. Patients were divided into three groups: (I) no distal esophageal pressurization (contraction wave amplitude <30 mmHg); (II) rapidly propagating compartmentalized pressurization (panesophageal pressurization >30 mmHg); and (III) rapidly propagating pressurization attributable to spastic contractions. Treatment failure was defined as a postoperative symptom score greater than the 10th percentile of the preoperative score (i.e., >7). Type III achalasia coincided with a longer overall lower esophageal sphincter (LES) length, a lower symptom score, and a smaller esophageal diameter. Treatment failure rates differed significantly in the three groups: I = 14.6% (14/96), II = 4.7% (6/127), and III = 30.4% (7/23; p = 0.0007). At univariate analysis, the manometric pattern, a low LES resting pressure, and a high chest pain score were the only factors predicting treatment failure. At multivariate analysis, the manometric pattern and a LES resting pressure <30 mmHg predicted a negative outcome. This is the first study by a surgical group to assess the outcome of surgery in 3 manometric achalasia subtypes: patients with panesophageal pressurization have the best outcome after laparoscopic Heller-Dor myotomy.

The psychological contracts of National Health Service nurses.

PubMed

Purvis, Lynne J; Cropley, Mark

2003-03-01

Following the psychological contract model of the employee-employer exchange relationship is offered as a means of understanding the expectations of a UK sample of 223 National Health Service (NHS) nurses in association with their leaving intentions. A pilot study involving 21 NHS nurses, using the repertory grid technique was conducted to elicit contract expectations. Twenty-nine categories of expectation were identified through content analysis. The study proper, employed a survey developed on the basis of results from the pilot study to identify contract profiles among 223 nurses from three London/South-east NHS hospitals, using the Q-sort method. Type of contract held (relational/transactional), satisfaction (job and organization), and leaving intentions were also examined. Q-analysis yielded four contract profiles among the nurses sampled: 'self-development and achievement'; 'belonging and development'; 'competence and collegiality' and 'autonomy and development'. Correlation analysis demonstrated that leaving intentions were associated with a need for personal autonomy and development, and the violation of expectations for being appreciated, valued, recognized and rewarded for effort, loyalty, hard-work and achievement, negative endorsement of a relational contract, positive endorsement of a transactional contract, and job and organizational dissatisfaction. Findings illustrate the diagnostic utility of the term psychological contract for understanding the expectations of NHS nurses. The potential significance of these findings for managing nurse retention is highlighted.

24 CFR 982.455 - Automatic termination of HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Automatic termination of HAP contract. 982.455 Section 982.455 Housing and Urban Development Regulations Relating to Housing and Urban... Payments Contract and Owner Responsibility § 982.455 Automatic termination of HAP contract. The HAP...

Evaluation of contract time estimation and contracting procedures for louisiana department of transportation and development construction projects : final report : volume I.

DOT National Transportation Integrated Search

1995-09-11

The purpose of the research was to provide the Louisiana Department of Transportation and Development (LaDOTD) with a systematic approach to the determination of contract time and to explore innovative contracting procedures that may prove beneficial...

24 CFR 983.205 - Term of HAP contract.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Term of HAP contract. 983.205 Section 983.205 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Housing Assistance Payments Contract § 983.205 Term of HAP...

24 CFR 983.205 - Term of HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Term of HAP contract. 983.205 Section 983.205 Housing and Urban Development Regulations Relating to Housing and Urban Development... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Housing Assistance Payments Contract § 983.205 Term of HAP...

48 CFR 16.103 - Negotiating contract type.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Selecting Contract Types 16.103 Negotiating contract... basic profit motive of business enterprise, shall be used when the risk involved is minimal or can be...) Contracts on a firm fixed-price basis other than those for major systems or research and development, and (3...

48 CFR 1515.606-70 - Contracting methods.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contracting methods. 1515... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 1515.606-70 Contracting methods. The Department of Housing and Urban Development-Independent Agencies Appropriation Act...

48 CFR 1515.606-70 - Contracting methods.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Contracting methods. 1515... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 1515.606-70 Contracting methods. The Department of Housing and Urban Development-Independent Agencies Appropriation Act...

48 CFR 1515.606-70 - Contracting methods.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contracting methods. 1515... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 1515.606-70 Contracting methods. The Department of Housing and Urban Development-Independent Agencies Appropriation Act...

48 CFR 1515.606-70 - Contracting methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contracting methods. 1515... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 1515.606-70 Contracting methods. The Department of Housing and Urban Development-Independent Agencies Appropriation Act...

48 CFR 1515.606-70 - Contracting methods.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Contracting methods. 1515... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 1515.606-70 Contracting methods. The Department of Housing and Urban Development-Independent Agencies Appropriation Act...

Synthesis and X-ray Crystallography of [Mg(H2O)6][AnO2(C2H5COO)3]2 (An = U, Np, or Pu).

PubMed

Serezhkin, Viktor N; Grigoriev, Mikhail S; Abdulmyanov, Aleksey R; Fedoseev, Aleksandr M; Savchenkov, Anton V; Serezhkina, Larisa B

2016-08-01

Synthesis and X-ray crystallography of single crystals of [Mg(H2O)6][AnO2(C2H5COO)3]2, where An = U (I), Np (II), or Pu (III), are reported. Compounds I-III are isostructural and crystallize in the trigonal crystal system. The structures of I-III are built of hydrated magnesium cations [Mg(H2O)6](2+) and mononuclear [AnO2(C2H5COO)3](-) complexes, which belong to the AB(01)3 crystallochemical group of uranyl complexes (A = AnO2(2+), B(01) = C2H5COO(-)). Peculiarities of intermolecular interactions in the structures of [Mg(H2O)6][UO2(L)3]2 complexes depending on the carboxylate ion L (acetate, propionate, or n-butyrate) are investigated using the method of molecular Voronoi-Dirichlet polyhedra. Actinide contraction in the series of U(VI)-Np(VI)-Pu(VI) in compounds I-III is reflected in a decrease in the mean An═O bond lengths and in the volume and sphericity degree of Voronoi-Dirichlet polyhedra of An atoms.

Radiative Feedback from Primordial Protostars and Final Mass of the First Stars

NASA Technical Reports Server (NTRS)

Hosokawa, Takashi; Omukai, Kazuyuki; Yoshida, Naoki; Yorke, Harold W.

2012-01-01

In this contribution, we review our efforts toward understanding the typical mass-scale of primordial stars. Our direct numerical simulations show that, in both of Population III.1 and III.2 cases, strong UV stellar radiative feedback terminatesmass accretion onto a protostar.AnHII region formed around the protostar very dynamically expands throughout the gas accreting envelope, which cuts off the gas supply to a circumstellar disk. The disk is exposed to the stellar UV radiation and loses its mass by photoevaporation. The derived final masses are 43 Stellar Mass and 17 Stellar Mass in our fiducial Population III.1 and III.2 cases. Much more massive stars should form in other exceptional conditions. In atomic-cooling halos where H2 molecules are dissociated, for instance, a protostar grows via very rapid mass accretion with the rates M* approx. 0.1 - 1 Stellar Mass/yr. Our newstellar evolution calculations show that the protostar significantly inflates and never contracts to reach the ZAMS stage in this case. Such the "supergiant protostars" have very low UV luminosity, which results in weak radiative feedback against the accretion flow. In the early universe, supermassive stars formed through this process might provide massive seeds of supermassive black holes.

Changing interdigestive migrating motor complex in rats under acute liver injury.

PubMed

Liu, Mei; Zheng, Su-Jun; Xu, Weihong; Zhang, Jianying; Chen, Yu; Duan, Zhongping

2014-01-01

Gastrointestinal motility disorder is a major clinical manifestation of acute liver injury, and interdigestive migrating motor complex (MMC) is an important indicator. We investigated the changes and characteristics of MMC in rats with acute liver injury. Acute liver injury was created by d-galactosamine, and we recorded the interdigestive MMC using a multichannel physiological recorder and compared the indexes of interdigestive MMC. Compared with normal controls, antral MMC Phase I duration was significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury. The duodenal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury. The jejunal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury compared with normal controls. Compared with the normal controls, rats with acute liver injury had a significantly prolonged interdigestive MMC cycle, related mainly to longer MMC Phases I and IV, shortened MMC Phase III, and MMC Phase II characterized by increased migrating clustered contractions, which were probably major contributors to the gastrointestinal motility disorders.

24 CFR 983.206 - HAP contract amendments (to add or substitute contract units).

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HAP contract amendments (to add or... Contract § 983.206 HAP contract amendments (to add or substitute contract units). (a) Amendment to substitute contract units. At the discretion of the PHA and subject to all PBV requirements, the HAP contract...

Research and Development of Silicon Carbide (SiC) Junction Recovery Diodes for Picosecond Range, High Power Opening Switches

NASA Astrophysics Data System (ADS)

Grekhov, Igor V.

2002-07-01

This report results from a contract tasking Ioffe Institute as follows: The purpose of the proposed project is to develop, fabricate, test, and characterize silicon carbide power semiconductor opening switches operating in the picosecond range of switch time. Special SiC diode structures will be fabricated and investigated, including Junction Recovery Diodes (JRD). The operation of such diodes is founded on the superfast recovery of the junction's blocking ability after switching the device from forward to reverse bias conditions. Our estimations show that the parameters of JRD devices can be substantially improved in case of SiC devices, compared to both Si and GaAs capabilities. We expect i) to increase the speed of switch operation, the specific commutated power, and the operation frequency repetition; ii) to reduce the weight and size of pulse devices; and iii) to achieve better reliability of the devices due to the unique thermal conductivity and radiation hardness of SiC.

Inducible error-prone repair in B. subtilis. Final report, September 1, 1979-June 30, 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yasbin, R. E.

1981-06-01

The research performed under this contract has been concentrated on the relationship between inducible DNA repair systems, mutagenesis and the competent state in the gram positive bacterium Bacillus subtilis. The following results have been obtained from this research: (1) competent Bacillus subtilis cells have been developed into a sensitive tester system for carcinogens; (2) competent B. subtilis cells have an efficient excision-repair system, however, this system will not function on bacteriophage DNA taken into the cell via the process of transfection; (3) DNA polymerase III is essential in the mechanism of the process of W-reactivation; (4) B. subtilis strains curedmore » of their defective prophages have been isolated and are now being developed for gene cloning systems; (5) protoplasts of B. subtilis have been shown capable of acquiring DNA repair enzymes (i.e., enzyme therapy); and (6) a plasmid was characterized which enhanced inducible error-prone repair in a gram positive organism.« less

Isometric parameters in the monitoring of maximal strength, power, and hypertrophic resistance-training.

PubMed

Peltonen, Heikki; Walker, Simon; Lähitie, Anuliisa; Häkkinen, Keijo; Avela, Janne

2018-02-01

This study monitored strength-training adaptations via isometric parameters throughout 2 × 10 weeks of hypertrophic (HYP I-II) or 10 weeks maximum strength (MS) followed by 10 weeks power (P) training with untrained controls. Trainees performed bilateral isometric leg press tests analyzed for peak force (maximal voluntary contraction (MVC)) and rate of force development (RFD) every 3.5 weeks. These parameters were compared with dynamic performance, voluntary and electrically induced isometric contractions, muscle activity, and cross-sectional area (CSA) in the laboratory before and after 10 and 20 weeks. RFD increased similarly during the first 7 weeks (HYP I, 44% ± 53%; MS, 48% ± 55%, P < 0.05), but RFD continued to increase up to 65% ± 61% from baseline (P < 0.01) only during P. These increases were concomitant with enhanced dynamic performances of 1-repetition maximum (1RM) (HYP I, 8% ± 6%; MS, 11% ± 6%, P < 0.001), and explosive repetitions during P (11% ± 15%, P < 0.05). Time to reach peak RFD differed (P < 0.001) between HYP (mean 42 ± 20 ms) and MS-P (mean 31 ± 12 ms) groups because of training. The changes in MVC correlated with the changes in CSA during weeks 1-20 (HYP I-II, r = 0.664; MS-P, r = 0.595, P ≤ 0.05), as well as changes in 1RM (r = 0.724, P < 0.05) during weeks 11-20 (HYP II). Muscle activity increased during MS and P only. Both MVC and RFD improvements reflected combinations of central and peripheral adaptations. RFD parameters may be effective tools to evaluate adaptations, particularly during maximal strength/power training, while MVC cannot distinguish between strength or muscle mass changes. Monitoring RFD provided important information regarding plateaus in RFD improvement, which were observed in dynamic explosive performances after HYP II compared with P.

48 CFR 731.773 - Independent research and development costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Independent research and development costs. 731.773 Section 731.773 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit...

48 CFR 731.773 - Independent research and development costs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Independent research and development costs. 731.773 Section 731.773 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit...

48 CFR 716.303 - Cost-sharing contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Cost-sharing contracts. 716.303 Section 716.303 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost Reimbursement Contracts 716.303 Cost-sharing...

48 CFR 716.303 - Cost-sharing contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Cost-sharing contracts. 716.303 Section 716.303 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost Reimbursement Contracts 716.303 Cost-sharing...

Validation Test Report for WAVEWATCH III

DTIC Science & Technology

2012-11-30

scales relevant to operation of a zodiac , to larger length-scales, relevant to activities on the largest ships, such as ship-to-ship transfer of...average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data...display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

Role of PTEN in the Tumor Microenvironment

DTIC Science & Technology

2008-06-01

van Diest PJ. (2008). Hexokinase III, cyclin A and galectin - 3 are overexpressed in malignant follicular thyroid nodules. Clin Endocrinol (Oxf) 2...Annual 3 . DATES COVERED (From - To) 15 May 2007 – 14 May 2008 4. TITLE AND SUBTITLE Role of PTEN in the Tumor Microenvironment 5a. CONTRACT NUMBER...1998) that impacts several signaling pathways, including phosphoinositide 3 -kinase (PI3K), and Ras-MAPK-Erk1/2 signaling pathways. Pten inactivation

Feasibility of a Modified Chloramine Process for the Production of UDMH and MMH

DTIC Science & Technology

1978-08-31

that phase is provided in this report . Amine Fuels Production Feasibility Demonstration, MCR -75-466, Final Report and Addendurn I - Data Book, Martin ...Final Report , Martin Marietta Corporation, Denver (February 1976) Contract F04701-74-C-0039. Amine Fuels Production Feasibility Demonstration, MCF-75...466, CDRL A305, Volume I, Final Report ; Volume II Economic Analyses; and Volume III, Data Book; Martin Marietta Corporation, Denver (October 1976

Extensions and Adjuncts to the BRL-COMGEOM Program

DTIC Science & Technology

1974-08-01

m MAGIC Code, GIFT Code, Computer Simulation, Target Description, Geometric Modeling Techniques, Vulnerability Analysis 20...Arbitrary Quadric Surf ace.. 0Oo „<>. 7 III. BRITL: A GEOMETRY PREPROCESSOR PROGRAM FOR INPUT TO THE GIFT SYSTEM „ 0 18 A. Introduction <, „. ° 18 B...the BRL- GIFT code. The tasks completed under this contract and described in the report are: Ao The addition to the list of available body types

Analysis of return on investment for Naval air station fallon energy project Alternatives

DTIC Science & Technology

2017-06-01

Second Reader: Daniel Nussbaum THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704–0188 Public reporting...Standard Form 298 (Rev. 2–89) Prescribed by ANSI Std. 239–18 ii THIS PAGE INTENTIONALLY LEFT BLANK iii Approved for public release...be awarded in its current form as an Energy Savings Performance Contract (ESPC). This analysis can support the decision- making process for similar

Regional discrimination studies: Phase III. Scientific report No. 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonner, J.; Herrin, E.; Sorrells, G.G.

1997-03-01

This report consists of three parts. Part 1, `Construction of Regional Ground Truth Data Bases Using Seismic And Infrasound Data` is by Gordon Sorrells, Eugene Herrin, and Jessie Bonner with contributions from Jack Swanson, Sarah Deering and Angela Maddox. Part 2, `Seismic And Infrasound Data Observations At TXAR` is by Jessie Bonner, Sarah Deering, Tao Liu, Jack Swanson and Ileana Tibuleac. Part 3, consists of the Acknowledgments called for by the contract.

Military Intelligence Fusion for Complex Operations: A New Paradigm

DTIC Science & Technology

2012-01-01

TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) RAND Corporation,National Defense Research Institute,1776 Main...Street, P.O. Box 2138,Santa Monica,CA,90407-2138 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10...Community under Contract W74V8H-06-C-0002. iii Preface This occasional paper examines how military intelligence organizations and, more broadly, the

Generation of Recombinant Human AChE OP-Scavengers with Extended Circulatory Longevity

DTIC Science & Technology

2006-11-01

PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Avigdor Shafferman Ph.D. 5d. PROJECT NUMBER 5e. TASK NUMBER E-Mail: avigdor...glycans of rHuAChE, and in particular the distal termini of these glycan 8 projections , constitute a major factor in determining the circulatory...experiments funded by sources other than the USAMRMC contract, since they may have a major impact on the present project . Section III focuses on the

Advanced Microwave Ferrite Research (AMFeR): Phase Three

DTIC Science & Technology

2008-07-31

lApril 1, 2006 thru June 30, 2008 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Advanced Microwave Ferrite Research (AMFeR): Phase Three 5b. GRANT NUMBER...Advance Microwave Ferrite Research (AMFeR), Phase III project. The purpose of this research endeavor is to devise ferrite materials for microwave, self...biased circulator applications. The central task of the project is to fabricate ferrites that have a high magnetic saturation, high coercivity and low

Domestic Trends in the United States, China, and Iran. Implications for U.S. Navy Strategic Planning

DTIC Science & Technology

2008-01-01

ABUSE TERRORISM AND HOMELAND SECURITY TRANSPORTATION AND INFRASTRUCTURE WORKFORCE AND WORKPLACE The RAND Corporation is a nonprofit research...Marine Corps, the defense agencies, and the defense Intelligence Community under Contract W74V8H-06-C-0002. iii Preface This book examines the future... Intelligence Community. For more information on RAND’s International Security and Defense Policy Center, contact the Director, James Dobbins. He can be

A Case Study of an Aeronautical Systems Division System Program Office.

DTIC Science & Technology

1982-09-01

11111 -’.-- m 1 1.25 111111.4 1 1.6_ MICROCOPY RESOLUTION TEST CHART NATIONAL BUREAU OF STANDARDS-1963-A If. t 1’ I I( N 2> - .~.. * .~ .~-I ~ k~’ ~K ~r...office....assesses.................. 8 Section 11 The Standard Aircraft Sensor UnitProgram........ 32 Section III Terms and Defnition ...contracts with industry, (b) test programs with both industry and other DOD organizations, (c) aircraft production or modification programs with both

Energy service contracts in regional engineering center for small and medium businesses

NASA Astrophysics Data System (ADS)

Gil'manshin, I. R.; Kashapov, N. F.

2014-12-01

The analysis of the energy service contracts development in Russia is given in the article. The role of the Complex learning centres in the field of energy efficiency in the promotion of energy service contracts is described. The reasons of constraining the development of energy service contracts are described.

Motilin-induced gastric contractions signal hunger in man.

PubMed

Tack, J; Deloose, E; Ang, D; Scarpellini, E; Vanuytsel, T; Van Oudenhove, L; Depoortere, I

2016-02-01

Hunger is controlled by the brain, which receives input from signals of the GI tract (GIT). During fasting, GIT displays a cyclical motor pattern, the migrating motor complex (MMC), regulated by motilin. To study the relationship between hunger and MMC phases (I-III), focusing on spontaneous and pharmacologically induced phase III and the correlation with plasma motilin and ghrelin levels. The role of phase III was also studied in the return of hunger after a meal in healthy individuals and in patients with loss of appetite. In fasting healthy volunteers, mean hunger ratings during a gastric (62.5±7.5) but not a duodenal (40.4±5.4) phase III were higher (p<0.0005) than during phase I (27.4±4.7) and phase II (37±4.5). The motilin agonist erythromycin, but not the cholinesterase inhibitor neostigmine, induced a premature gastric phase III, which coincided with an increase in hunger scores from 29.2±7 to 61.7±8. The somatostatin analogue octreotide induced a premature intestinal phase III without a rise in hunger scores. Hunger ratings significantly correlated (β=0.05; p=0.01) with motilin plasma levels, and this relationship was lost after erythromycin administration. Motilin, but not ghrelin administration, induced a premature gastric phase III and a rise in hunger scores. In contrast to octreotide, postprandial administration of erythromycin induced a premature gastric phase III accompanied by an early rise in hunger ratings. In patients with unexplained loss of appetite, gastric phase III was absent and hunger ratings were lower. Motilin-induced gastric phase III is a hunger signal from GIT in man. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 235.072 - Additional contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracts for research and development. (d) Use the clause at 252.235-7011, Final Scientific or Technical Report, in solicitations and contracts for research and development. (e) Use the clause at 252.235-7004...

48 CFR 731.370 - Predetermined fixed rates for indirect costs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts... determining the indirect costs applicable under contracts with educational institutions. ...

48 CFR 731.370 - Predetermined fixed rates for indirect costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts... determining the indirect costs applicable under contracts with educational institutions. ...

Guidelines for cost control and analysis of cost-type research and development contracts

NASA Technical Reports Server (NTRS)

Sibbers, C. W.

1981-01-01

The cost information which should be obtained from a contractor(s) on a major, cost type research and development contract(s), and the analyses and effective use of these data are discussed. Specific type(s) of information which should be required, methods for analyzing such information, and methods for effectively using the results of such analyses to enhance NASA contract and project management are included. The material presented is based primarily on the principal methods which have been effectively used in the management of major cost type research and development contracts.

48 CFR 728.309 - Contract clause for worker's compensation insurance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 728.309 Contract clause... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clause for worker... resulting in contracts which require worker's compensation insurance, USAID has contracted with an insurance...

48 CFR 728.309 - Contract clause for worker's compensation insurance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 728.309 Contract clause... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause for worker... resulting in contracts which require worker's compensation insurance, USAID has contracted with an insurance...

24 CFR 891.560 - HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HAP contract. 891.560 Section 891... Assistance § 891.560 HAP contract. (a) HAP contract. The housing assistance payments contract sets forth.... (b) HAP contract execution. (1) Upon satisfactory completion of the project, the Borrower and HUD...

31 CFR 537.410 - Contracts and subcontracts regarding economic development of resources in Burma.

Code of Federal Regulations, 2011 CFR

2011-07-01

... economic development of resources in Burma. 537.410 Section 537.410 Money and Finance: Treasury Regulations... BURMESE SANCTIONS REGULATIONS Interpretations § 537.410 Contracts and subcontracts regarding economic... supervision and guarantee of another person's performance of a contract that includes the economic development...

Partial transformation from fast to slow muscle fibers induced by deafferentation of capsaicin-sensitive muscle afferents.

PubMed

Brunetti, O; Barazzoni, A M; Della Torre, G; Clavenzani, P; Pettorossi, V E; Bortolami, R

1997-11-01

Mechanical and histochemical characteristics of the lateral gastrocnemius (LG) muscle of the rat were examined 21 days after capsaicin injection into the LG muscle. The capsaicin caused a decrease in generation rate of twitch and tetanic tension and an increase in fatigue resistance of LG muscle. The histochemical muscle fiber profile evaluated by myosin adenosine triphosphatase and reduced nicotinamide adenine dinucleotide tetrazolium reductase methods showed an increase of type I and IIC fibers and a decrease of the type IIB in whole muscle, and a decrease of the IIA, IIX fibers in the red part accompanied by their increase in the white part. Therefore the capsaicin treatment, which selectively eliminated fibers belonging to the III and IV groups of muscle afferents, induced muscle fiber transformation from fast contracting fatiguing fibers to slowly contracting nonfatiguing ones.

Identifying Psychological Contract Breaches to Guide Improvements in Faculty Recruitment, Retention, and Development

PubMed Central

Desselle, Shane P.; Draugalis, JoLaine R.; Spies, Alan R.; Davis, Tamra S.; Bolino, Mark

2012-01-01

Objective. To identify pharmacy faculty members’ perceptions of psychological contract breaches that can be used to guide improvements in faculty recruitment, retention, and development. Methods. A list of psychological contract breaches was developed using a Delphi procedure involving a panel of experts assembled through purposive sampling. The Delphi consisted of 4 rounds, the first of which elicited examples of psychological contract breaches in an open-ended format. The ensuing 3 rounds consisting of a survey and anonymous feedback on aggregated group responses. Results. Usable responses were obtained from 11 of 12 faculty members who completed the Delphi procedure. The final list of psychological contract breaches included 27 items, after modifications based on participant feedback in subsequent rounds. Conclusion. The psychological contract breach items generated in this study provide guidance for colleges and schools of pharmacy regarding important aspects of faculty recruitment, retention, and development. PMID:22919084

Identifying psychological contract breaches to guide improvements in faculty recruitment, retention, and development.

PubMed

Peirce, Gretchen L; Desselle, Shane P; Draugalis, JoLaine R; Spies, Alan R; Davis, Tamra S; Bolino, Mark

2012-08-10

To identify pharmacy faculty members' perceptions of psychological contract breaches that can be used to guide improvements in faculty recruitment, retention, and development. A list of psychological contract breaches was developed using a Delphi procedure involving a panel of experts assembled through purposive sampling. The Delphi consisted of 4 rounds, the first of which elicited examples of psychological contract breaches in an open-ended format. The ensuing 3 rounds consisting of a survey and anonymous feedback on aggregated group responses. Usable responses were obtained from 11 of 12 faculty members who completed the Delphi procedure. The final list of psychological contract breaches included 27 items, after modifications based on participant feedback in subsequent rounds. The psychological contract breach items generated in this study provide guidance for colleges and schools of pharmacy regarding important aspects of faculty recruitment, retention, and development.

48 CFR 39.107 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.107 Contract clause. The contracting officer..., in solicitations and contracts for information technology which require security of information technology, and/or are for the design, development, or operation of a system of records using commercial...

48 CFR 39.107 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.107 Contract clause. The contracting officer..., in solicitations and contracts for information technology which require security of information technology, and/or are for the design, development, or operation of a system of records using commercial...

48 CFR 39.107 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.107 Contract clause. The contracting officer..., in solicitations and contracts for information technology which require security of information technology, and/or are for the design, development, or operation of a system of records using commercial...

48 CFR 39.107 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.107 Contract clause. The contracting officer..., in solicitations and contracts for information technology which require security of information technology, and/or are for the design, development, or operation of a system of records using commercial...

48 CFR 747.507 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 747.507 Section 747.507 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 747.507 Contract clauses. Contracting...

48 CFR 1828.370 - Fixed-price contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Fixed-price contract... ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 1828.370 Fixed-price contract... Risk, in all negotiated fixed-price contracts for the development, production, modification...

48 CFR 9.504 - Contracting officer responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., contracting officers shall analyze planned acquisitions in order to— (1) Identify and evaluate potential..., or mitigate significant potential conflicts before contract award. (b) Contracting officers should... potential conflicts and in developing any necessary solicitation provisions and contract clauses (see 9.506...

48 CFR 732.111 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 732.111 Section 732.111 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING General 732.111 Contract clauses. (a) [Reserved] (b) USAID may...

48 CFR 732.111 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clauses. 732.111 Section 732.111 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING General 732.111 Contract clauses. (a) [Reserved] (b) USAID may...

48 CFR 2432.906 - Contract financing payments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract financing payments. 2432.906 Section 2432.906 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Prompt Payment 2432.906 Contract financing...

Veterans Affairs Contracting: Improved Oversight Needed for Certain Contractual Arrangements

DTIC Science & Technology

2015-07-01

Federally Funded Research and Development Center HCA Head of Contracting Activity IAA interagency agreement IDIQ indefinite-delivery indefinite...contracts reside in six different VA organizations. Each of these organizations has an individual designated as Head of Contracting Activity ( HCA ), who...properly trained, stating that HCAs shall develop and implement guidance ensuring only qualified individuals with appropriate training are assigned to

Formation of the U.S. Air Force Aviator Post Traumatic Stress Disorder Study Group

DTIC Science & Technology

2016-11-15

to endorse PTSD during all four subsequent evaluations. Notably, they found that lingering symptoms of PTSD occurred frequently for both groups of...AFRL-SA-WP-TR-2016-0017 Formation of the U.S. Air Force Aviator Post-Traumatic Stress Disorder Study Group Joe D. Wood, III...Aviator Post-Traumatic Stress Disorder Study Group 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Joe D

Method of Analysis for Determining and Correcting Mirror Deformation due to Gravity

DTIC Science & Technology

2014-01-01

obtainable. 1.3 Description of As-Built Beam Compressor Assembly The as-built beam compressor assembly consists of primary and secondary Zerodur ® mirrors held...Method of analysis for determining and correcting mirror deformation due to gravity James H. Clark, III F. Ernesto, Penado Downloaded From: http...00-00-2014 4. TITLE AND SUBTITLE Method of analysis for determining and correcting mirror deformation due to gravity 5a. CONTRACT NUMBER 5b. GRANT

Distributed Memory Breadth-First Search Revisited: Enabling Bottom-Up Search

DTIC Science & Technology

2013-01-03

Jun. 1972. [2] W. McLendon III, B. Hendrickson, S . J. Plimpton , and L. Rauchwerger, “Finding strongly connected components in distributed graphs,” J...Breadth-First Search Revisited: Enabling Bottom-Up Search 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT...NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of California at Berkeley,Electrical

Final Environmental Impact Statement. Second KC-135R Air Refueling Squadron, Malmstrom Air Force Base, Montana

DTIC Science & Technology

1989-07-01

commercial center in the area. Those two counties are Cascade and Lewis & Clark. Population and Demographics. The ROI for this element includes areas...commercial trade, finance, III-2 II transportation, and service sectors of the area ( originating primarily in Great Falls) serve north-central Montana and...Malmstrom AFB through contracts with local and regional distributors that are filled through the Defense Fuels Supply Center I (DFSC). The fuel is

American Burn Association Practice Guidelines: Burn Shock Resuscitation

DTIC Science & Technology

2008-02-01

Ann Surg 1979;189: 546–52. 39. Jelenko C III, Williams JB, Wheeler ML, et al. Studies in shock and resuscitation, I: use of a hypertonic, albumin...SUMMARY ARTICLE American Burn Association Practice Guidelines Burn Shock Resuscitation Tam N. Pham, MD,* Leopoldo C . Cancio, MD,† Nicole S. Gibran...practice guidelines burn shock resuscitation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Pham T. N., Cancio L. C

Efficacy and Mode of Action of Immune Response Modifying Compounds against Alphaviruses and Flaviviruses

DTIC Science & Technology

1987-12-01

previously noted the exquisite sensitivity of this marker to any changes in the peritoneal compartment (1,42). The experiments also confirmed that these...immunomodulators. (iii) Antiviral activity of cells other than those investigated may be primary in antiviral resistance. For example, liver Kupffer MO may be the...characterzation of Kuoffer cells (KC). During the contract year we 14 have finalized our isolation procedure for Kupffer cells (see experimental methods) and

A taxonomy and results from a comprehensive review of 28 maternal health voucher programmes.

PubMed

Bellows, Ben W; Conlon, Claudia M; Higgs, Elizabeth S; Townsend, John W; Nahed, Matta G; Cavanaugh, Karen; Grainger, Corinne G; Okal, Jerry; Gorter, Anna C

2013-12-01

It is increasingly clear that Millennium Development Goal 4 and 5 will not be achieved in many low- and middle-income countries with the weakest gains among the poor. Recognizing that there are large inequalities in reproductive health outcomes, the post-2015 agenda on universal health coverage will likely generate strategies that target resources where maternal and newborn deaths are the highest. In 2012, the United States Agency for International Development convened an Evidence Summit to review the knowledge and gaps on the utilization of financial incentives to enhance the quality and uptake of maternal healthcare. The goal was to provide donors and governments of the low- and middle-income countries with evidence-informed recommendations on practice, policy, and strategies regarding the use of financial incentives, including vouchers, to enhance the demand and supply of maternal health services. The findings in this paper are intended to guide governments interested in maternal health voucher programmes with recommendations for sustainable implementation and impact. The Evidence Summit undertook a systematic review of five financing strategies. This paper presents the methods and findings for vouchers, building on a taxonomy to catalogue knowledge about voucher programme design and functionality. More than 120 characteristics under five major categories were identified: programme principles (objectives and financing); governance and management; benefits package and beneficiary targeting; providers (contracting and service pricing); and implementation arrangements (marketing, claims processing, and monitoring and evaluation). Among the 28 identified maternal health voucher programmes, common characteristics included: a stated objective to increase the use of services among the means-tested poor; contracted-out programme management; contracting either exclusively private facilities or a mix of public and private providers; prioritizing community-based distribution of vouchers; and tracking individual claims for performance purposes. Maternal voucher programmes differed on whether contracted providers were given training on clinical or administrative issues; whether some form of service verification was undertaken at facility or community-level; and the relative size of programme management costs in the overall programme budget. Evidence suggests voucher programmes can serve populations with national-level impact. Reaching scale depends on whether the voucher programme can: (i) keep management costs low, (ii) induce a large demand-side response among the bottom two quintiles, and (iii) achieve a quality of care that translates a greater number of facility-based deliveries into a reduction in maternal morbidity and mortality.

A Taxonomy and Results from a Comprehensive Review of 28 Maternal Health Voucher Programmes

PubMed Central

Conlon, Claudia M.; Higgs, Elizabeth S.; Townsend, John W.; Nahed, Matta G.; Cavanaugh, Karen; Grainger, Corinne G.; Okal, Jerry; Gorter, Anna C.

2013-01-01

It is increasingly clear that Millennium Development Goal 4 and 5 will not be achieved in many low- and middle-income countries with the weakest gains among the poor. Recognizing that there are large inequalities in reproductive health outcomes, the post-2015 agenda on universal health coverage will likely generate strategies that target resources where maternal and newborn deaths are the highest. In 2012, the United States Agency for International Development convened an Evidence Summit to review the knowledge and gaps on the utilization of financial incentives to enhance the quality and uptake of maternal healthcare. The goal was to provide donors and governments of the low- and middle-income countries with evidence-informed recommendations on practice, policy, and strategies regarding the use of financial incentives, including vouchers, to enhance the demand and supply of maternal health services. The findings in this paper are intended to guide governments interested in maternal health voucher programmes with recommendations for sustainable implementation and impact. The Evidence Summit undertook a systematic review of five financing strategies. This paper presents the methods and findings for vouchers, building on a taxonomy to catalogue knowledge about voucher programme design and functionality. More than 120 characteristics under five major categories were identified: programme principles (objectives and financing); governance and management; benefits package and beneficiary targeting; providers (contracting and service pricing); and implementation arrangements (marketing, claims processing, and monitoring and evaluation). Among the 28 identified maternal health voucher programmes, common characteristics included: a stated objective to increase the use of services among the means-tested poor; contracted-out programme management; contracting either exclusively private facilities or a mix of public and private providers; prioritizing community-based distribution of vouchers; and tracking individual claims for performance purposes. Maternal voucher programmes differed on whether contracted providers were given training on clinical or administrative issues; whether some form of service verification was undertaken at facility or community-level; and the relative size of programme management costs in the overall programme budget. Evidence suggests voucher programmes can serve populations with national-level impact. Reaching scale depends on whether the voucher programme can: (i) keep management costs low, (ii) induce a large demand-side response among the bottom two quintiles, and (iii) achieve a quality of care that translates a greater number of facility-based deliveries into a reduction in maternal morbidity and mortality.

48 CFR 917.7301-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 917.7301-1 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Program Research and Development Announcements 917.7301-1... in entering into arrangements for research, development, and related projects in specified areas of...

Sustaining Financial Support through Workforce Development Grants and Contracts

ERIC Educational Resources Information Center

Brumbach, Mary A.

2005-01-01

Workforce development grants and contracts are important methods for sustaining financial support for community colleges. This chapter details decision factors, college issues, possible pitfalls, and methods for procuring and handling government contracts and grants for workforce training.

48 CFR 35.006 - Contracting methods and contract type.

Code of Federal Regulations, 2010 CFR

2010-10-01

... short-duration fixed-price contract may be useful for developing system design concepts, resolving... contracts as designs become more firmly established, risks are reduced, and production tooling, equipment...

20 CFR Appendix A to Part 401 - Employee Standards of Conduct

Code of Federal Regulations, 2011 CFR

2011-04-01

... arrangements for the design, development, or operation of any system of records without making reasonable... provisions: (1) Contracts for design, or development of systems and equipment. The contracting officer shall not enter into any contract for the design or development of a system of records, or for equipment to...

20 CFR Appendix A to Part 401 - Employee Standards of Conduct

Code of Federal Regulations, 2010 CFR

2010-04-01

... arrangements for the design, development, or operation of any system of records without making reasonable... provisions: (1) Contracts for design, or development of systems and equipment. The contracting officer shall not enter into any contract for the design or development of a system of records, or for equipment to...

24 CFR 203.257 - Creation of the contract.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Creation of the contract. 203.257 Section 203.257 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 203.257 Creation of the contract. The mortgage shall be an insured mortgage from the date of the...

24 CFR 203.257 - Creation of the contract.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Creation of the contract. 203.257 Section 203.257 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 203.257 Creation of the contract. The mortgage shall be an insured mortgage from the date of the...

24 CFR 203.257 - Creation of the contract.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Creation of the contract. 203.257 Section 203.257 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 203.257 Creation of the contract. The mortgage shall be an insured mortgage from the date of the...

24 CFR 203.257 - Creation of the contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Creation of the contract. 203.257 Section 203.257 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 203.257 Creation of the contract. The mortgage shall be an insured mortgage from the date of the...

24 CFR 203.257 - Creation of the contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Creation of the contract. 203.257 Section 203.257 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 203.257 Creation of the contract. The mortgage shall be an insured mortgage from the date of the...

48 CFR 250.104-3-70 - Indemnification under contracts involving both research and development and other work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts involving both research and development and other work. 250.104-3-70 Section 250.104-3-70 Federal... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 250.104-3-70 Indemnification under contracts involving both research and development and other work. When...

48 CFR 2446.502-70 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 2446.502-70 Section 2446.502-70 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONTRACT MANAGEMENT QUALITY ASSURANCE Acceptance 2446.502-70 Contract clause. The Contracting...

48 CFR 43.205 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer or other professional services, and no supplies are to be furnished, the contracting officer shall...-engineer or other professional services, the contracting officer shall use the clause with its Alternate... Accounting, in solicitations and contracts for supply and research and development contracts of significant...

48 CFR 43.205 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-engineer or other professional services, and no supplies are to be furnished, the contracting officer shall...-engineer or other professional services, the contracting officer shall use the clause with its Alternate... Accounting, in solicitations and contracts for supply and research and development contracts of significant...

48 CFR 43.205 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer or other professional services, and no supplies are to be furnished, the contracting officer shall...-engineer or other professional services, the contracting officer shall use the clause with its Alternate... Accounting, in solicitations and contracts for supply and research and development contracts of significant...

48 CFR 43.205 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer or other professional services, and no supplies are to be furnished, the contracting officer shall...-engineer or other professional services, the contracting officer shall use the clause with its Alternate... Accounting, in solicitations and contracts for supply and research and development contracts of significant...

48 CFR 43.205 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer or other professional services, and no supplies are to be furnished, the contracting officer shall...-engineer or other professional services, the contracting officer shall use the clause with its Alternate... Accounting, in solicitations and contracts for supply and research and development contracts of significant...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 742.1170-4 - Progress reporting requirements and contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirements and contract clause. 742.1170-4 Section 742.1170-4 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Production, Surveillance, and Reporting 742.1170-4 Progress reporting requirements and contract clause. (a) When the requiring...

48 CFR 1535.007-70 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract clauses. 1535.007-70 Section 1535.007-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1535.007-70 Contract clauses. The following...

48 CFR 1535.007-70 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contract clauses. 1535.007-70 Section 1535.007-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1535.007-70 Contract clauses. The following...

48 CFR 1535.007-70 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Contract clauses. 1535.007-70 Section 1535.007-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1535.007-70 Contract clauses. The following...

48 CFR 1535.007-70 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Contract clauses. 1535.007-70 Section 1535.007-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1535.007-70 Contract clauses. The following...

48 CFR 2432.114 - Unusual contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Unusual contract financing... DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 2432.114 Unusual contract financing. The Senior Procurement Executive is the agency head for the purpose of...

24 CFR 242.52 - Construction contracts.

Code of Federal Regulations, 2013 CFR

2013-04-01

...; a construction management contract with a guaranteed maximum price, the final costs of which are... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Construction contracts. 242.52... MORTGAGE INSURANCE FOR HOSPITALS Construction § 242.52 Construction contracts. (a) Awarding of contract. A...

24 CFR 206.131 - Contract rights and obligations for mortgages on individual dwelling units in a condominium.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Contract rights and obligations for... MORTGAGE INSURANCE Contract Rights and Obligations Condominiums § 206.131 Contract rights and obligations...] Termination of Insurance Contract ...

48 CFR 2432.703-3 - Contracts crossing fiscal years.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contracts crossing fiscal years. 2432.703-3 Section 2432.703-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Contract Funding 2432.703-3...

48 CFR 301.603-70 - Delegation of Contracting Officer responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Delegation of Contracting... HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 301.603-70 Delegation of Contracting Officer responsibilities. (a) Contracting Officers may re...