Background Poor adherence to medication is one of the limitations in the treatment of cardiovascular diseases, thereby increasing the risk of premature death, hospital admissions, and related costs. There is a need for simple and easy-to-implement interventions that are based on patients’ perspectives, beliefs, and perceptions of their illness and medication. Objective The objective is to test the effectivity of this intervention to improve medication adherence in patients with established cardiovascular disease, that is, in secondary prevention. Methods In this study the effect of a personalized visualization of cardiovascular risk levels through a website aiming at supporting self management in combination with a group consultation and communication intervention by a nurse on adherence to treatment in 600 patients with manifest cardiovascular diseases will be assessed. The health belief model was chosen as main theoretical model for the intervention. Results Primary outcome is adherence to treatment calculated by refill data. Secondary outcomes include the Beliefs about Medication Questionnaire and the Modified Morisky Scale. Patients are followed for one year. Results are expected by 2015. Conclusions This study assesses adherence to treatment in a high-risk cardiovascular population by applying an intervention that addresses patients’ capacity and practical barriers as well as patients’ beliefs and perceptions of their illness and medication. ClinicalTrial ClinicalTrials.gov NCT01449695; https://clinicaltrials.gov/ct2/show/NCT01449695 (Archived by WebCite at http://www.webcitation.org/6kCzkIKH3) PMID:27624877
Dimitriou, Christopher J; McKinley, Gareth H
Guided by a series of discriminating rheometric tests, we develop a new constitutive model that can quantitatively predict the key rheological features of waxy crude oils. We first develop a series of model crude oils, which are characterized by a complex thixotropic and yielding behavior that strongly depends on the shear history of the sample. We then outline the development of an appropriate preparation protocol for carrying out rheological measurements, to ensure consistent and reproducible initial conditions. We use RheoPIV measurements of the local kinematics within the fluid under imposed deformations in order to validate the selection of a particular protocol. Velocimetric measurements are also used to document the presence of material instabilities within the model crude oil under conditions of imposed steady shearing. These instabilities are a result of the underlying non-monotonic steady flow curve of the material. Three distinct deformation histories are then used to probe the material's constitutive response. These deformations are steady shear, transient response to startup of steady shear with different aging times, and large amplitude oscillatory shear (LAOS). The material response to these three different flows is used to motivate the development of an appropriate constitutive model. This model (termed the IKH model) is based on a framework adopted from plasticity theory and implements an additive strain decomposition into characteristic reversible (elastic) and irreversible (plastic) contributions, coupled with the physical processes of isotropic and kinematic hardening. Comparisons of experimental to simulated response for all three flows show good quantitative agreement, validating the chosen approach for developing constitutive models for this class of materials. PMID:25008187
Prilipko, V A; Shevchenko, K K
Metoiu danogo doslidzhennia stala ekspertna otsinka realizatsiI zakhysnykh zakhodiv, spriamovanykh na obmezhennia op rominennia naselennia zony sposterezhennia atomnoI elektrostantsiI, na vypadok nadzvychaynoI sytuatsiI, z urakhu vanniam zakonodavchykh ta normatyvnykh dokumentiv.Metody. V protsesi doslidzhennia bulo zastosovano opytuvannia z vykorystanniam metodu ekspertnykh otsinok. Sformovano chotyry grupy fakhivtsiv, iaki nesut' vidpovidal'nist' za stan radiatsiynogo zakhystu riznykh grup nase lennia zony sposterezhennia Rivnens'koI atomnoI elektrostantsiI. Vymogamy vidboru buly: dosvid roboty za fa khom ne mensh nizh 10 rokiv, vidpovidnyy profil' ta posada. Dlia otrymannia pervynnykh empirychnykh danykh bulo zastosovano proste uporiadkuvannia znachen', Ikh parne chy poslidovne porivniannia.Rezul'taty. Za otsinkamy ekspertiv, zakhody opovishchennia, zabezpechenist' preparatamy stabil'nogo yodu, zabezpe chennia zasobiv kolektyvnogo (zakhysni sporudy, ukryttia) i indyvidual'nogo zakhystu (odiag, marlevi pov’iazky, respiratory, protyvogazy), material'no tekhnichnogo osnashchennia na vypadok nadzvychaynoI sytuatsiI na Rivnens'kiy atomniy elektrostantsiI suttievo vidrizniaiut'sia u sil's'kogo ta mis'kogo naselennia zony spostere zhennia. Grupoiu ryzyku, na vypadok nadzvychaynoI sytuatsiI, mozhut' staty uchni zagal'noosvitnikh shkil sil's'kykh te rytoriy zony sposterezhennia cherez nedoskonalist' systemy opovishchennia i vidsutnist' neobkhidnykh ob’iektiv ukryt tia. Ne isnuie odnostaynosti sered ekspertiv shchodo otsinok radiatsiynogo zakhystu riznykh grup naselennia zony spos terezhennia, zokrema zabezpechenosti zasobamy indyvidual'nogo i kolektyvnogo zakhystu, gotovnosti do zakhysnykh diy na vypadok nadzvychaynoI sytuatsiI.Vysnovky. Stan radiatsiynogo zakhystu naselennia zony sposterezhennia RAES, zokrema systema organizatsiynykh, tekhnichnykh, medyko biologichnykh, finansovo ekonomichnykh zakhodiv, shchodo zapobigannia ta reaguvannia na nadzvy chayni sytuatsi
Stepanova, Ye I; Kolpakov, Ye; Zyhalo, V M; Lytvynets, O M; Kondrashova, V H; Vdovenko, V Yu; Skvarska, O O; Leonovych, O S
asotsiyovani z naiavnistiu u genotypi aleliu 4a, oznak endo telial'noI dysfunktsiI ta rivnem inkorporovanogo 137Cs.Vysnovky. Bil'sh vyrazni zminy endoteliyzalezhnoI reaktsiI sudyn na okliuziiu ta virogidne znyzhennia rivnia nitry tu v syrovattsi krovi u nosiIv aleliu 4a, osoblyvo u ditey, iaki prozhyvaiut' u nespryiatlyvykh ekologichnykh umovakh, nadaie pidstavy vidnesty Ikh do grupy ryzyku z rozvytku endotelial'noI dysfunktsiI, a porushennia funktsiI legeniv rozgliadaty iak odyn z II proiaviv.
Tugjamba, Navchaa; Sereeter, Erdenetuul; Gonchigjav, Sarantuya
Developing the ecosystem based adaptation strategies to maintain water security in critical water catchments in Mongolia would be very significant. It will be base by reducing the vulnerability. "Ecosystem Based adaptation" is quite a new term in Mongolia and the ecosystem approach is a strategy for the integrated management of land, water and living resources that promotes conservation and sustainable use in an equitable way. To strengthen equitable economic development, food security, climate resilience and protection of the environment, the implementation of sustainable river basin management in critical water catchments is challenging in Mongolia. The Ulz river basin is considered one of the critical water catchments due to the temperature has increased by in average 1.30Ñ over the period 1976 to 2011. It is more intense than the global warming rate (0.740C/100 years) and a bit higher than the warming rate over whole Mongolia as well. From long-term observations and measurements it is clear that Ulz River has low water in a period of 1970-1980 and since the end of 1980s and middle of 1990s there were dominated years of the flood. However, under the influence of the global warming, climate changes of Mongolia and continuation of drought years with low water since the end of 1990s until today river water was sharply fallen and dried up. For the last ten years rivers are dried up and annual mean run-off is less by 3-5 times from long term mean value. The Ulz is the transboundary river basin and taking its origin from Ikh and Baga Burd springs on territory of Norovlin soum of Khentii province that flows through Khentii and Dornod provinces to the northeast, crossing the state border it flows in Baruun Tari located in Tari Lake concavity in Russia. Based on the integrative baseline study on the 'The Ulz River Basin Environmental and Socioeconomic condition', ecosystem based river basin management was planned. 'Water demand Calculator 3' (WDC) software was used to
khukhuudei, Ulambadrakh; otgonbayar, Orolzodmaa
- K-Ar age for Mesozoic volcanic rocks from Eastern Mongolia and Ikh Khyangan dated in range from 160 to 110Ma (Shuvalov, 1987; Makhbadar et al., 1995; Zhou et al., 2006; Bat-Ulzii, 2014). 2. Rift controlling fault - Delgerekh, Modon Ovoo and Matad faults to north-east direction are interpreted and presented in EMP (Khasin, 1973; Tikhonov, 1974; Byamba, 2009). 3. Basin and Range topography - we are interpreting that Nukhet davaa mountain range, Tamsag basin, Matad uplift or range and Choibalsan basin were developed in that time. Hills with 40-150 m height at a present day are interpreted that they developed from the Late Cretaceous period. In post- rift or Late Cretaceous period, lakes disappeared and whole area of Eastern Mongolia became a dry land, dominating by exogenic process. Denudation planation surface at EMP are kept in high and low level. High or old planation surface is proposed by age of the Miocene - Lower Pliocene and low or young planation surface - Late Pliocene. Just a current topography of EMP is formed in Late Neogene - Lower Quaternary period as a peneplain.
Borodavko, P. S.
cane sedges and horsetails dominant. The benthic fauna is poor, and only single pecimens of molluscs and amphipods are met. The ichtyofauna is represented by Oreoleuciscus Pewzowi. Previous and modern investigations of these lakes, their morphologies and deposits, allow to specify periods of extension of the lakes and palaeogeographical conditions. Two clear extension periods can be determined in the Mongolian Great Lakes Basin, corresponding to Mid-and Late Pleistocene transgressions. During the Mid-Pleistocene transgression the current Lakes Har-Us Nur, Dorgon Nur, Hara Nur, Airag Nur and Hyargas were integrated to a united lake, with a maximal level at 1265 m. and total water area about 23 158 km2 . The maximal thickness of Mid-Pleistocene lake deposits is 70 m. Late Pleistocene lake sediments are investigated in sections near Dzabhan River and Hyargas Nuur shorelines. They consist of laminated sand, clay and gravel with cryogenic structures at the base and upper part of sections. The mean thickness of Late Pleistocene lake deposits is 20-35 m. The main characteristics of Late Pleistocene lake features are represented by a very bright "lake relief" — obvious steps of shorelines, gravel bands, bars and spits. The specific structure of Late Pleistocene lake cross-sections allows to separate two transgressions within this period. In the first half of the Holocene a minor regression of several meters occurred. Elements of the modern time aeolian relief were still inundated on the north shore of Lake Har-Us Nur. Researches funded by RFBR (Grant 08-05-00037-a) References 1. Geomorfologiya Mongol'skoi Narodnoi Respubliki (Geomorphology of the Mongolian People Republic). M.: Nauka, pp. 135-148. 2. Ozera MNR i ikh mineral'nye resursy (Lakes of MPR and their mineral resources), 1991. Moscow, Nauka, 136 p. 3. Sevastyanov, D.V., Shuvalov, V.F. and Neustrueva, I. Yu. (Eds.), 1994. Limnologiya i paleolimnologiya Mongolii (Limnology and Palaeolimnology of Mongolia). St