Ischaemia-modified albumin: a marker of bacterial infection in hospitalized patients with cirrhosis.

PubMed

Giannone, Ferdinando A; Domenicali, Marco; Baldassarre, Maurizio; Bartoletti, Michele; Naldi, Marina; Laggetta, Maristella; Bertucci, Carlo; Colecchia, Antonio; Viale, Pierluigi; Bernardi, Mauro; Caraceni, Paolo

2015-11-01

Patients with cirrhosis present structural changes of human serum albumin (HSA) affecting non-oncotic functions. Ischaemia-modified albumin (IMA), which reflects the capacity to bind cobalt, has been associated to patient mortality during acute-on-chronic liver failure. This study aimed to assess whether circulating IMA is elevated in advanced cirrhosis and its relationship with severity of cirrhosis and specific complications. A total of 127 cirrhotic patients hospitalized for an acute complication of the disease and 44 healthy controls were enrolled. Plasma IMA and IMA to albumin ratio (IMAr) were measured with a cobalt-binding assay. HSA isoforms carrying post-transcriptional molecular changes were assessed with HPLC-ESI-MS. The effect of endotoxemia on IMA was evaluated in rats with CCl4 -cirrhosis. IMA/IMAr is significantly higher in cirrhotic patients than in controls, but no correlations were found with prognostic scores. IMA did not correlate with the altered HSA isoforms. Ascites, renal impairment and hepatic encephalopathy did not influence IMA/IMAr levels. In contrast, IMA/IMAr is significantly higher in infected than non-infected patients. ROC curves showed that IMA/IMAr had similar discriminating performances for bacterial infection as C-reactive protein (CRP). Moreover, CRP and IMA were independently associated with bacterial infection. Consistently, endotoxin injection significantly increased IMA in cirrhotic, but not in healthy rats. IMA is elevated in patients with advanced cirrhosis. The IMA level does not correlate with disease severity scores, but it is specifically associated to bacterial infection, showing a discriminating performance similar to CRP. Further investigations to assess IMA as a novel diagnostic test for bacterial infection are advocated. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

ARCUS Internet Media Archive (IMA): A Resource for Outreach and Education

NASA Astrophysics Data System (ADS)

Polly, Z.; Warnick, W. K.; Polly, J.

2008-12-01

The ARCUS Internet Media Archive (IMA) is a collection of photos, graphics, videos, and presentations about the Arctic that are shared through the Internet. It provides the arctic research community and the public at large with a centralized location where images and video pertaining to polar research can be browsed and retrieved for a variety of uses. The IMA currently contains almost 6,500 publicly accessible photos, including 4,000 photos from the National Science Foundation funded Teachers and Researchers Exploring and Collaborating (TREC, now PolarTREC) program, an educational research experience in which K-12 teachers participate in arctic research as a pathway to improving science education. The IMA also includes 450 video files, 270 audio files, nearly 100 graphics and logos, 28 presentations, and approximately 10,000 additional resources that are being prepared for public access. The contents of this archive are organized by file type, contributor's name, event, or by organization, with each photo or file accompanied by information on content, contributor source, and usage requirements. All the files are key-worded and all information, including file name and description, is completely searchable. ARCUS plans to continue to improve and expand the IMA with a particular focus on providing graphics depicting key arctic research results and findings as well as edited video archives of relevant scientific community meetings. To submit files or for more information and to view the ARCUS Internet Media Archive, please go to: http://media.arcus.org or email photo@arcus.org.

A Role for Caenorhabditis elegans Importin IMA-2 in Germ Line and Embryonic Mitosis

PubMed Central

Geles, Kenneth G.; Johnson, Jeffrey J.; Jong, Sena; Adam, Stephen A.

2002-01-01

The importin α family of nuclear-cytoplasmic transport factors mediates the nuclear localization of proteins containing classical nuclear localization signals. Metazoan animals express multiple importin α proteins, suggesting their possible roles in cell differentiation and development. Adult Caenorhabditis elegans hermaphrodites express three importin α proteins, IMA-1, IMA-2, and IMA-3, each with a distinct expression and localization pattern. IMA-2 was expressed exclusively in germ line cells from the early embryonic through adult stages. The protein has a dynamic pattern of localization dependent on the stage of the cell cycle. In interphase germ cells and embryonic cells, IMA-2 is cytoplasmic and nuclear envelope associated, whereas in developing oocytes, the protein is cytoplasmic and intranuclear. During mitosis in germ line cells and embryos, IMA-2 surrounded the condensed chromosomes but was not directly associated with the mitotic spindle. The timing of IMA-2 nuclear localization suggested that the protein surrounded the chromosomes after fenestration of the nuclear envelope in prometaphase. Depletion of IMA-2 by RNA-mediated gene interference (RNAi) resulted in embryonic lethality and a terminal aneuploid phenotype. ima-2(RNAi) embryos have severe defects in nuclear envelope formation, accumulating nucleoporins and lamin in the cytoplasm. We conclude that IMA-2 is required for proper chromosome dynamics in germ line and early embryonic mitosis and is involved in nuclear envelope assembly at the conclusion of mitosis. PMID:12221121

A study of compositional verification based IMA integration method

NASA Astrophysics Data System (ADS)

Huang, Hui; Zhang, Guoquan; Xu, Wanmeng

2018-03-01

The rapid development of avionics systems is driving the application of integrated modular avionics (IMA) systems. But meanwhile it is improving avionics system integration, complexity of system test. Then we need simplify the method of IMA system test. The IMA system supports a module platform that runs multiple applications, and shares processing resources. Compared with federated avionics system, IMA system is difficult to isolate failure. Therefore, IMA system verification will face the critical problem is how to test shared resources of multiple application. For a simple avionics system, traditional test methods are easily realizing to test a whole system. But for a complex system, it is hard completed to totally test a huge and integrated avionics system. Then this paper provides using compositional-verification theory in IMA system test, so that reducing processes of test and improving efficiency, consequently economizing costs of IMA system integration.

Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae

PubMed Central

Deng, Xu; Petitjean, Marjorie; Teste, Marie-Ange; Kooli, Wafa; Tranier, Samuel; François, Jean Marie; Parrou, Jean-Luc

2014-01-01

The yeast Saccharomyces cerevisiae IMA multigene family encodes four isomaltases sharing high sequence identity from 65% to 99%. Here, we explore their functional diversity, with exhaustive in-vitro characterization of their enzymological and biochemical properties. The four isoenzymes exhibited a preference for the α-(1,6) disaccharides isomaltose and palatinose, with Michaëlis–Menten kinetics and inhibition at high substrates concentration. They were also able to hydrolyze trisaccharides bearing an α-(1,6) linkage, but also α-(1,2), α-(1,3) and α-(1,5) disaccharides including sucrose, highlighting their substrate ambiguity. While Ima1p and Ima2p presented almost identical characteristics, our results nevertheless showed many singularities within this protein family. In particular, Ima3p presented lower activities and thermostability than Ima2p despite only three different amino acids between the sequences of these two isoforms. The Ima3p_R279Q variant recovered activity levels of Ima2p, while the Leu-to-Pro substitution at position 240 significantly increased the stability of Ima3p and supported the role of prolines in thermostability. The most distant protein, Ima5p, presented the lowest optimal temperature and was also extremely sensitive to temperature. Isomaltose hydrolysis by Ima5p challenged previous conclusions about the requirement of specific amino acids for determining the specificity for α-(1,6) substrates. We finally found a mixed inhibition by maltose for Ima5p while, contrary to a previous work, Ima1p inhibition by maltose was competitive at very low isomaltose concentrations and uncompetitive as the substrate concentration increased. Altogether, this work illustrates that a gene family encoding proteins with strong sequence similarities can lead to enzyme with notable differences in biochemical and enzymological properties. PMID:24649402

Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae.

PubMed

Deng, Xu; Petitjean, Marjorie; Teste, Marie-Ange; Kooli, Wafa; Tranier, Samuel; François, Jean Marie; Parrou, Jean-Luc

2014-01-01

The yeast Saccharomyces cerevisiae IMA multigene family encodes four isomaltases sharing high sequence identity from 65% to 99%. Here, we explore their functional diversity, with exhaustive in-vitro characterization of their enzymological and biochemical properties. The four isoenzymes exhibited a preference for the α-(1,6) disaccharides isomaltose and palatinose, with Michaëlis-Menten kinetics and inhibition at high substrates concentration. They were also able to hydrolyze trisaccharides bearing an α-(1,6) linkage, but also α-(1,2), α-(1,3) and α-(1,5) disaccharides including sucrose, highlighting their substrate ambiguity. While Ima1p and Ima2p presented almost identical characteristics, our results nevertheless showed many singularities within this protein family. In particular, Ima3p presented lower activities and thermostability than Ima2p despite only three different amino acids between the sequences of these two isoforms. The Ima3p_R279Q variant recovered activity levels of Ima2p, while the Leu-to-Pro substitution at position 240 significantly increased the stability of Ima3p and supported the role of prolines in thermostability. The most distant protein, Ima5p, presented the lowest optimal temperature and was also extremely sensitive to temperature. Isomaltose hydrolysis by Ima5p challenged previous conclusions about the requirement of specific amino acids for determining the specificity for α-(1,6) substrates. We finally found a mixed inhibition by maltose for Ima5p while, contrary to a previous work, Ima1p inhibition by maltose was competitive at very low isomaltose concentrations and uncompetitive as the substrate concentration increased. Altogether, this work illustrates that a gene family encoding proteins with strong sequence similarities can lead to enzyme with notable differences in biochemical and enzymological properties.

15 years of monitoring occupational exposure to respirable dust and quartz within the European industrial minerals sector.

PubMed

Zilaout, Hicham; Vlaanderen, Jelle; Houba, Remko; Kromhout, Hans

2017-07-01

In 2000, a prospective Dust Monitoring Program (DMP) was started in which measurements of worker's exposure to respirable dust and quartz are collected in member companies from the European Industrial Minerals Association (IMA-Europe). After 15 years, the resulting IMA-DMP database allows a detailed overview of exposure levels of respirable dust and quartz over time within this industrial sector. Our aim is to describe the IMA-DMP and the current state of the corresponding database which due to continuation of the IMA-DMP is still growing. The future use of the database will also be highlighted including its utility for the industrial minerals producing sector. Exposure data are being obtained following a common protocol including a standardized sampling strategy, standardized sampling and analytical methods and a data management system. Following strict quality control procedures, exposure data are consequently added to a central database. The data comprises personal exposure measurements including auxiliary information on work and other conditions during sampling. Currently, the IMA-DMP database consists of almost 28,000 personal measurements which have been performed from 2000 until 2015 representing 29 half-yearly sampling campaigns. The exposure data have been collected from 160 different worksites owned by 35 industrial mineral companies and comes from 23 European countries and approximately 5000 workers. The IMA-DMP database provides the European minerals sector with reliable data regarding worker personal exposures to respirable dust and quartz. The database can be used as a powerful tool to address outstanding scientific issues on long-term exposure trends and exposure variability, and importantly, as a surveillance tool to evaluate exposure control measures. The database will be valuable for future epidemiological studies on respiratory health effects and will allow for estimation of quantitative exposure response relationships. Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.

A potent combination of the novel PI3K inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal

PubMed Central

Floris, Giuseppe; Wozniak, Agnieszka; Sciot, Raf; Li, Haifu; Friedman, Lori; Van Looy, Thomas; Wellens, Jasmien; Vermaelen, Peter; Deroose, Christophe M.; Fletcher, Jonathan A.; Debiec-Rychter, Maria; Schöffski, Patrick

2015-01-01

Introduction Oncogenic signaling in gastrointestinal stromal tumors (GIST) is sustained via PI3K/AKT pathway. We used a panel of six GIST xenograft models to assess efficacy of GDC-0941 as single agent or in combination with imatinib (IMA). Experimental design Nude mice (n=136) were grafted bilaterally with human GIST carrying divers KIT mutations. Mice were orally dosed over four weeks, grouped as follows: A) control; B) GDC-0941; C) IMA and D) GDC+IMA treatments. Xenografts re-growth after treatment discontinuation was assessed in group C and D for additional four weeks. Tumor response was assessed by volume measurements, micro-PET imaging, histopathology and immunoblotting. Moreover genomic alterations in PTEN/PI3K/AKT pathway were evaluated. Results In all models, GDC-0941 caused tumor growth stabilization, inhibiting tumor cells proliferation but did not induce apoptosis. Under GDC+IMA, profound tumor regression, superior to either treatment alone, was observed. This effect was associated with the best histologic response, a nearly complete proliferation arrest and increased apoptosis. Tumor re-growth assays confirmed superior activity of GDC+IMA over IMA; in three out of six models tumor volume remained reduced and stable even after treatment discontinuation. A positive correlation between response to GDC+IMA and PTEN loss, both on gene and protein levels, was found. Conclusion GDC+IMA has significant antitumor efficacy in GIST xenografts, inducing more substantial tumor regression, apoptosis and durable effects than IMA. Notably, after treatment withdrawal, tumor regression was sustained in tumors exposed to GDC+IMA, which was not observed under IMA. Assessment of PTEN status may represent a useful predictive biomarker for patient selection. PMID:23231951

On TTEthernet for Integrated Fault-Tolerant Spacecraft Networks

NASA Technical Reports Server (NTRS)

Loveless, Andrew

2015-01-01

There has recently been a push for adopting integrated modular avionics (IMA) principles in designing spacecraft architectures. This consolidation of multiple vehicle functions to shared computing platforms can significantly reduce spacecraft cost, weight, and de- sign complexity. Ethernet technology is attractive for inclusion in more integrated avionic systems due to its high speed, flexibility, and the availability of inexpensive commercial off-the-shelf (COTS) components. Furthermore, Ethernet can be augmented with a variety of quality of service (QoS) enhancements that enable its use for transmitting critical data. TTEthernet introduces a decentralized clock synchronization paradigm enabling the use of time-triggered Ethernet messaging appropriate for hard real-time applications. TTEthernet can also provide two forms of event-driven communication, therefore accommodating the full spectrum of traffic criticality levels required in IMA architectures. This paper explores the application of TTEthernet technology to future IMA spacecraft architectures as part of the Avionics and Software (A&S) project chartered by NASA's Advanced Exploration Systems (AES) program.

[Establishment and testing practice of an integrative medical pathway for clinical management of acute myocardial infarction].

PubMed

Wang, Lei; Zhang, Min-zhou; Zhang, Jun

2011-01-01

To establish an integrative medical approach (IMA) for clinical management of acute myocardial infarction (AMI), and to test its efficacy. IMA was preliminarily established according to the guidelines and based on the Chinese medical therapy of benefiting vital qi and promoting blood circulation. And adopting non-synchronous queue design, AMI patients were assigned to the IMA group (71 cases) and the non-IMA group (70 cases), they were managed following or didn't follow the established IMA respectively. The total hospitalization time (THT), the ICU indwelling time (ICUD) and the total medical expenditure (TME) of patients were compared between groups. Moreover, for patients received primary PCI, the time for door-to-balloon (DTB) was compared in addition. Comparisons between groups showed that THT in the IMA group was shorter than that in the non-IMA group (9.80 +/- 5.62 days vs. 12.01 +/- 7. 35 days , P < 0.05); but the difference of TME between groups was insignificant. For those received PCT, the DTB in the IMA group was shorter than that in the non-IMA group in terms of DTB time (82.56 +/- 17.36 min vs. 119.19 +/- 30.88 min, P < 0.01), THT (9.69 +/- 5.59 vs. 13.34 +/- 7.49 days, P < 0.01) and TME. Practicing IMA for AMI, which was established based on Chinese medical therapy of benefiting vital qi and promoting blood circulation, could shorten the hospitalization time of patients, reduce the DTB time and TME in patients receiving primary PCI; fully displays its significance in hospital administration and quality control on AMI.

Association of ideomotor apraxia with lesion site, etiology, neglect, and functional independence in patients with first ever stroke.

PubMed

Civelek, Gul Mete; Atalay, Ayce; Turhan, Nur

2015-04-01

Ideomotor apraxia (IMA) is characterized by the inability to correctly imitate hand gestures and voluntarily pantomime tool use. The relationship between IMA and characteristics of stroke has not been totally elucidated. This study aimed to find out associations between presence of IMA and stroke etiology, site of the lesions, neglect, and temporal and functional parameters of stroke in patients with first ever stroke. Thirty-nine patients with first ever stroke were included. Patients with severe cognitive deficits were excluded. Assessment tools included Ideomotor Apraxia Test, Functional Independence Measure (FIM), Brunnstrom recovery stages, Mini Mental Test (MMT), and star cancellation test. Etiology (hemorrhagic or ischemic) and site of stroke was assessed through brain imaging methods. Location and size of ischemic lesion was determined by using the Oxfordshire Community Stroke Project system. IMA was identified in 35.9% of the patients. Patients with IMA had significantly lower FIM scores both on admission and discharge (P = 0.001, P = 0.001). Presence of IMA was significantly associated with the presence of neglect (P = 0.004), total anterior circulation ischemia (TACI) (P < 0.001), and lower MMT scores (P < 0.001). Lesion site, patient age, time since onset, and stroke etiology had no impact on the presence of IMA. IMA was in concordance with poor cognitive and functional state and was not limited to left hemisphere lesions. The study revealed strong associations between IMA, neglect, and TACI. Every patient with stroke should be evaluated for the presence of IMA on admission to rehabilitation unit.

Vagal Intramuscular Arrays: The Specialized Mechanoreceptor Arbors That Innervate the Smooth Muscle Layers of the Stomach Examined in the Rat

PubMed Central

Powley, Terry L.; Hudson, Cherie N.; McAdams, Jennifer L.; Baronowsky, Elizabeth A.; Phillips, Robert J.

2016-01-01

The fundamental roles that the stomach plays in ingestion and digestion notwithstanding, little morphological information is available on vagal intramuscular arrays (IMAs), the afferents that innervate gastric smooth muscle. To characterize IMAs better, rats were given injections of dextran biotin in the nodose ganglia, and, after tracer transport, stomach whole mounts were collected. Specimens were processed for avidin–biotin permanent labeling, and subsets of the whole mounts were immunohistochemically processed for c-Kit or stained with cuprolinic blue. IMAs (n = 184) were digitized for morphometry and mapping. Throughout the gastric muscle wall, IMAs possessed common phenotypic features. Each IMA was generated by a parent neurite arborizing extensively, forming an array of multiple (mean = 212) branches averaging 193 μm in length. These branches paralleled, and coursed in apposition with, bundles of muscle fibers and interstitial cells of Cajal. Individual arrays averaged 4.3 mm in length and innervated volumes of muscle sheet, presumptive receptive fields, averaging 0.1 mm3. Evaluated by region and by muscle sheet, IMAs displayed architectural adaptations to the different loci. A subset (32%) of circular muscle IMAs issued specialized polymorphic collaterals to myenteric ganglia, and a subset (41%) of antral longitudinal muscle IMAs formed specialized net endings associated with the serosal boundary. IMAs were concentrated in regional patterns that correlated with the unique biomechanical adaptations of the stomach, specifically proximal stomach reservoir functions and antral emptying operations. Overall, the structural adaptations and distributions of the IMAs were consonant with the hypothesized stretch receptor roles of the afferents. PMID:26355387

A meta-analysis of the association of serum ischaemia-modified albumin levels with human hypothyroidism and hyperthyroidism.

PubMed

Reddy, Varikasuvu Seshadri; Bukke, Suman; Mahato, Khageshwar; Kumar, Vinod; Reddy, Netala Vasudeva; Munikumar, Manne; Vodelu, Bramahanapally

2017-02-28

Serum levels of ischaemia-modified albumin (IMA) have been studied as a novel and simple measure of oxidative stress (OXS) in different thyroid pathologies. However, results of available studies in the literature were not consistent. This meta-analysis was attempted to quantify the overall effect size for serum IMA levels in human hypothyroidism (HT) and hyperthyroidism (HYT) and to study its associations with the thyroid profile. Databases of PubMed/Medline, EMBASE, Google Scholar, Web of Science and Science Direct were searched for articles. Data on serum IMA levels in HT, HYT patients and euthyroid controls were extracted to compute standardized mean differences (SMD) by the random-effects model. The associations between IMA and thyroid profile were computed by the meta-analysis of correlation coefficients. IMA levels in HT patients (SMD=1.12; Z=2.76; P=0.006) and HYT patients (SMD=1.64; Z=2.57; P=0.01) were significantly higher than in euthyroid controls and the thyroid treatment showed a favourble effect on serum IMA levels. There were strong and significant correlations between IMA and hormonal status in HT and HYT groups. This meta-analysis showing increased IMA level in both HT and HYT patients and its association with thyroid profile suggests that serum IMA could be used as a simple measure of increased OXS in thyroid dysfunction. © 2017 The Author(s).

Wide sternal retraction may impede internal mammary artery graft flow and reduce myocardial function during off-pump coronary artery bypass grafting: presentation of two cases

PubMed Central

Espinoza, Andreas; Bergsland, Jacob; Lundblad, Runar; Fosse, Erik

2012-01-01

The internal mammary artery (IMA) is routinely used for grafting of the left anterior descending coronary artery (LAD), providing good flow to the anterior left ventricle (LV) wall. Impeded IMA-to-LAD flow may result in myocardial ischaemia and haemodynamic deterioration. From a study population, we describe two incidents where myocardial ischaemia was observed during off-pump coronary artery bypass surgery (CABG), with a confirmed reduction in the IMA-to-LAD flow in one patient. In patient no. 1, normal IMA flow was assessed by transit-time flow measurement after a complete IMA-to-LAD anastomosis. The anterior LV wall thickening was monitored continuously by epicardial ultrasonic transducers. Normal wall thickening was confirmed after IMA grafting. During a wide sternal opening for circumflex grafting the anterior wall motion displayed an ischaemic pattern, with reduced systolic and increased post-systolic wall thickening. IMA flow was reduced simultaneously. When easing the sternal opening, IMA flow normalized, as did the motion pattern in the anterior LV wall. In patient no. 2, similar changes in wall thickening occurred during a wide sternal opening after IMA-to-LAD grafting. When easing the retractor, the wall thickening normalized. It is important for the surgeon to be aware of this possible cause of myocardial ischaemia, with a risk of subsequent haemodynamic deterioration. This may not only be of great importance during off-pump CABG, but can also be significant for successful weaning from the cardiopulmonary bypass machine. PMID:22499803

Percutaneous protective coil occlusion of the proximal inferior mesenteric artery before N-butyl cyanoacrylate embolization of type II endoleaks after endovascular repair of abdominal aortic aneurysms.

PubMed

Chao, Christine P; Paz-Fumagalli, Ricardo; Walser, Eric M; McKinney, J Mark; Stockland, Andrew H; Falkensammer, Jürgen; Hakaim, Albert G; Oldenburg, W Andrew

2006-11-01

Bowel ischemia can complicate treatment of type II endoleak with liquid or semiliquid agents such as n-butyl cyanoacrylate (NBCA) if nontarget embolization of the inferior mesenteric artery (IMA) occurs. The current report describes four cases of type II endoleak in which the IMA was the main outflow vessel and was prophylactically occluded with embolization coils before NBCA injection into the endoleak nidus. The purpose was to prevent unintentional embolization of the NBCA into IMA branches. If feasible, protective IMA coil occlusion should be considered in type II endoleaks with IMA outflow in cases of NBCA embolization.

Experimenting Maintenance of Flight Software in an Integrated Modular Avionics for Space

NASA Astrophysics Data System (ADS)

Hardy, Johan; Laroche, Thomas; Creten, Philippe; Parisis, Paul; Hiller, Martin

2014-08-01

This paper presents an experiment of Flight Software partitioning in an Integrated Modular Avionics for Space (IMA-SP) system. This experiment also tackles the maintenance aspects of IMA-SP systems. The presented case study is PROBA-2 Flight Software. The paper addresses and discusses the following subjects: On-Board Software Maintenance in IMA- SP, boot strategy for Time and Space Partitioning, considerations about the ground segment related to On-Board Software Maintenance in IMA-SP, and architectural impacts of Time and Space Partitioning for PROBA software's. Finally, this paper presents the results and the achievements of the study and it appeals at further perspectives for IMA-SP and Time and Space Partitioning.

The Role of Ischemia Modified Albumin as a Biomarker in Patients with Chronic Liver Disease.

PubMed

Kumar, Prashanth Ashok; Subramanian, Kavitha

2016-03-01

Chronic Liver Disease (CLD) is characterised by gradual destruction of liver tissue over time. Ischemia Modified Albumin (IMA) is an upcoming biomarker shown to be elevated in conditions associated with ischemia and oxidative stress. Albumin levels are greatly reduced in patients with CLD and studying its alterations will provide essential information regarding the molecular changes occurring to it. The study aims to estimate IMA and IMA/Albumin ratio in patients with CLD and to correlate it with parameters assessing liver function and the Model for End Stage Liver Disease (MELD) score. The study consisted of 43 CLD patients as test subjects and 28 apparently healthy individuals as controls. Multiple parameters assessing liver function like albumin, bilirubin, aspartate transaminase (AST), alanine transaminase (ALT), Gamma Glutamyl Transpeptidase (GGT), alkaline phosphatase (ALP), Prothrombin Time (PT) INR and creatinine were estimated and the MELD score calculated. Serum IMA expressed as Absorbance Units (ABSU) was estimated using the Albumin Cobalt Binding test (ABT). Student's t-test and correlation coefficient was used for statistical analysis. Serum IMA was significantly higher in CLD patients (0.5320 ± 0.1677) as compared to the control group (0.3203 ± 0.1257) with a p-value of <0.0001. The IMA/Albumin ratio was also significantly higher (0.2035 ± 0.0970) in patients with CLD compared to control group (0.0714 ± 0.0283) with a p-value of <0.0001. IMA has a negative correlation with albumin. The IMA/Albumin ratio shows positive correlation with MELD score, bilirubin and ALP. There was no correlation with ALT, AST, GGT and PT INR. Decreased serum albumin correlates with increase in IMA in CLD could indicate a qualitative change and not merely a quantitative reduction of albumin. IMA can serve as a biomarker to assess the disease severity and prognosis of CLD patients.

Physiological response and productivity of safflower lines under water deficit and rehydration.

PubMed

Bortolheiro, Fernanda P A P; Silva, Marcelo A

2017-01-01

Water deficit is one of the major stresses affecting plant growth and productivity worldwide. Plants induce various morphological, physiological, biochemical and molecular changes to adapt to the changing environment. Safflower (Carthamus tinctorius L.), a potential oil producer, is highly adaptable to various environmental conditions, such as lack of rainfall and temperatures. The objective of this work was to study the physiological and production characteristics of six safflower lines in response to water deficit followed by rehydration. The experiment was conducted in a protected environment and consisted of 30 days of water deficit followed by 18 days of rehydration. A differential response in terms of photosynthetic pigments, electrolyte leakage, water potential, relative water content, grain yield, oil content, oil yield and water use efficiency was observed in the six lines under water stress. Lines IMA 04, IMA 10, IMA 14 showed physiological characteristics of drought tolerance, with IMA 14 and IMA 16 being the most productive after water deficit. IMA 02 and IMA 21 lines displayed intermediate characteristics of drought tolerance. It was concluded that the lines responded differently to water deficit stress, showing considerable genetic variation and influence to the environment.

[Copeptin and ischemia modified albumin in early diagnosis and prognosis of myocardial damage in acute organic phosphorus pesticide poisoning].

PubMed

Li, Jing; Zhang, Jianjun; Li, Na; Li, Jia; Liu, Juan; Liu, Qian

2015-03-01

To assess the value of combined detection of copeptin and ischemia modified albumin (IMA) in early diagnosis and prognostic evaluation of myocardial damage in patients with acute organic phosphorus pesticide poisoning (AOPP). A total of 126 AOPP patients were examined for blood copepin and IMA levels and myocardial injury markers within 1 h after admission. Copeptin and IMA levels significantly increased in patients with AOPP compared with those in the control subjects. Copeptin and IMA levels were significantly higher in severe AOPP cases than in mild to moderate cases (P<0.05). Logistic regression analysis showed that increased copeptin and IMA levels and severe complications of AOPP were associated with an increased risk of cardiovascular events. Early detection of copeptin and IMA levels has important clinical value in early diagnosis and prognostic evaluation of myocardial damage in patients with AOPP, and their levels are positively correlated with the severity of the condition.

A Cognitive Model of How Interactive Multimedia Authoring Facilitates Conceptual Understanding of Object-Oriented Programming in Novices

ERIC Educational Resources Information Center

Yuen, Timothy; Liu, Min

2011-01-01

This paper presents a cognitive model of how interactive multimedia authoring (IMA) affect novices' cognition in object-oriented programming. This model was generated through an empirical study of first year computer science students at the university level being engaged in interactive multimedia authoring of a role-playing game. Clinical…

Proximal Intermetatarsal Divergence in Distal Chevron Osteotomy for Hallux Valgus: An Overlooked Finding.

PubMed

Akpinar, Evren; Buyuk, Abdul Fettah; Cetinkaya, Engin; Gursu, Sarper; Ucpunar, Hanifi; Albayrak, Akif

2016-01-01

The goal of distal chevron osteotomy for hallux valgus is to restore proper first-toe joint alignment by performing lateral translation of the distal first metatarsal fragment (the metatarsal head). We hypothesized that in some patients this procedure might also result in involuntary medial translation of the proximal first metatarsal fragment, which we called proximal intermetatarsal divergence. The aim of the present study was to compare the pre- and postoperative radiographs of patients with hallux valgus to determine whether we could identify proximal intermetatarsal divergence. We retrospectively compared the pre- and postoperative radiographs of 29 feet in 28 patients treated with distal chevron osteotomy. Two different methods were used to measure the intermetatarsal angles: the anatomic intermetatarsal angle (aIMA) and the mechanical intermetatarsal angle (mIMA). The maximum intermetatarsal distance (MID) was also measured. We defined proximal intermetatarsal divergence as a postoperative increase in the aIMA or MID, coupled with a decrease in the mIMA. For data analysis, we divided the patients into low-angle (mild deformity) and high-angle (severe deformity) groups, according to their preoperative mIMA. The mean ± standard deviation patient age was 41 ± 14 years. In the low-angle group, the mean mIMA decreased (from 10.91° to 7.00°), the mean aIMA increased (from 11.80° to 13.55°), and the mean MID increased (from 17.97 mm to 20.60 mm; p = .001, for all). In the high-angle group, the mean mIMA decreased (from 14.30° to 6.90°; p = .001), the mean aIMA decreased (from 14.77° to 13.54°; p = .06), and the mean MID decreased (from 20.74 mm to 20.37 mm; p = .64). The results of our study suggest that proximal intermetatarsal divergence might occur after distal chevron osteotomy for hallux valgus, primarily in patients with a low preoperative mIMA. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Role of ischemia-modified albumin in the evaluation of oxidative stress in intrahepatic cholestasis of pregnancy.

PubMed

Tayyar, A T; Kozalı, S; Yıldırım, G Y; Karakus, R; Yuksel, I T; Erel, O; Neselioglu, S; Eroglu, M

2018-05-08

To investigate the ischemia-modified albumin (IMA) level, and the IMA/albumin ratio (IMAR) in healthy pregnant women, and pregnant women with intrahepatic cholestasis of pregnancy (ICP). This cross-sectional study included 53 women with ICP and 52 healthy pregnant women. Their serum IMA and albumin levels were analyzed, and the women were followed up to delivery. No significant intergroup differences were identified in maternal age, body mass index, and gestational age at the time that the blood samples were taken. The gestational age at delivery and the serum albumin level was significantly lower (p = 0.002 and p < 0.0001, respectively) in the ICP group than in the healthy pregnant women. Although no differences in IMA levels were shown between the groups, IMA/albumin levels were higher in the ICP group than in the healthy pregnant women (p = 0.004). Serum IMA levels did not differ between pregnant women with ICP and healthy pregnant women, while the IMAR was significantly higher in the ICP group versus the healthy pregnant women.

Ischemia-modified albumin levels in cerebrovascular accidents.

PubMed

Gunduz, Abdulkadir; Turedi, Suleyman; Mentese, Ahmet; Altunayoglu, Vildan; Turan, Ibrahim; Karahan, Suleyman Caner; Topbas, Murat; Aydin, Murat; Eraydin, Ismet; Akcan, Buket

2008-10-01

Previous studies have demonstrated that ischemia-modified albumin (IMA) is a useful marker for the diagnosis of ischemic events. It was also recently demonstrated that IMA levels increase in the acute phase of cerebrovascular diseases. Yet the data regarding IMA levels in various types of cerebrovascular events are insufficient. The aim of this study was to evaluate IMA levels in various types of cerebrovascular events such as ischemic stroke, subarachnoid hemorrhage (SAH), and intracranial hemorrhage. This case-controlled study consisted of 106 consecutive patients, 43 with brain infarction (BI), 11 with brain hemorrhage (ICH), 52 with SAH, and a 43-member control group. We investigated whether there was a statistical correlation between these 3 groups and the control group. The relations among the 3 groups were also examined. Comparisons among groups were done with analysis of variance. Mean serum IMA levels were 0.280 +/- 0.045 absorbance units (ABSU) for BI patients, 0.259 +/- 0.053 ABSU for ICH patients, 0.243 +/- 0.061 ABSU for SAH patients, and 0.172 +/- 0.045 ABSU for the control group.There was a statistically significant difference between the mean IMA levels of BI, ICH, and SAH patients and the mean control patient IMA levels (P b .0001). Ischemia-modified albumin levels are high in cerebrovascular diseases. Ischemia-modified albumin measurement can also be used to distinguish SAH from BI during the acute phase of cerebrovascular event in the emergency department.

Serum ischemia modified albumin is a possible new marker of oxidative stress in phenylketonuria.

PubMed

Keshavarzi, Fatemeh; Rastegar, Mohsen; Vessal, Mahmood; Rafiei Dehbidi, Gholamreza; Khorsand, Marjan; Ganjkarimi, Amir Hossein; Takhshid, Mohammad Ali

2018-06-01

The role of oxidative stress in the pathogenesis of phenylketonuria (PKU)-associated disorders has been implicated. Ischemia modified albumin (IMA) is a modified form of serum albumin, which is produced under the conditions of oxidative stress. The aim of this study was to measure the serum level of IMA in the PKU patients and to investigate its ability in predicting the status of oxidative stress in these patients. Fifty treated-PKU patients and fifty age- and sex-matched healthy subjects were included in the study. The blood samples were obtained and the serum level of phenylalanine (Phe) was measured using reverse phase HPLC method. The levels of IMA, malondialdehyde (MDA), gamma-glutamyl transferase (GGT) activity, and uric acid (UA) were determined using colorimetric methods. The levels of serum Phe, IMA, and MDA were significantly higher (p < 0.001) and the level of UA (p < 0.05) was lower in the PKU patients compared to control group. Serum IMA level was positively correlated with MDA (r = 0.585, p < 0.001) and UA (r = 0.6, p < 0.001). An inverse relationship was observed between the serum level of IMA and Phe (r = - 0.410, p < 0. 01). Results of the present study suggest that serum IMA level could be used as a novel marker for the evaluation of oxidative stress in the PKU patients.

Point-Connecting Measurements of the Hallux Valgus Deformity: A New Measurement and Its Clinical Application

PubMed Central

Seo, Jeong-Ho; Boedijono, Dimas

2016-01-01

Purpose The aim of this study was to investigate new point-connecting measurements for the hallux valgus angle (HVA) and the first intermetatarsal angle (IMA), which can reflect the degree of subluxation of the first metatarsophalangeal joint (MTPJ). Also, this study attempted to compare the validity of midline measurements and the new point-connecting measurements for the determination of HVA and IMA values. Materials and Methods Sixty feet of hallux valgus patients who underwent surgery between 2007 and 2011 were classified in terms of the severity of HVA, congruency of the first MTPJ, and type of chevron metatarsal osteotomy. On weight-bearing dorsal-plantar radiographs, HVA and IMA values were measured and compared preoperatively and postoperatively using both the conventional and new methods. Results Compared with midline measurements, point-connecting measurements showed higher inter- and intra-observer reliability for preoperative HVA/IMA and similar or higher inter- and intra-observer reliability for postoperative HVA/IMA. Patients who underwent distal chevron metatarsal osteotomy (DCMO) had higher intraclass correlation coefficient for inter- and intra-observer reliability for pre- and post-operative HVA and IMA measured by the point-connecting method compared with the midline method. All differences in the preoperative HVAs and IMAs determined by both the midline method and point-connecting methods were significant between the deviated group and subluxated groups (p=0.001). Conclusion The point-connecting method for measuring HVA and IMA in the subluxated first MTPJ may better reflect the severity of a HV deformity with higher reliability than the midline method, and is more useful in patients with DCMO than in patients with proximal chevron metatarsal osteotomy. PMID:26996576

CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides.

PubMed

Sergent, Thérèse; Dupont, Isabelle; Jassogne, Coralie; Ribonnet, Laurence; van der Heiden, Edwige; Scippo, Marie-Louise; Muller, Marc; McAlister, Dan; Pussemier, Luc; Larondelle, Yvan; Schneider, Yves-Jacques

2009-02-10

Imazalil (IMA) is a widely used imidazole-antifungal pesticide and, therefore, a food contaminant. This compound is also used as a drug (enilconazole). As intestine is the first site of exposure to ingested drugs and pollutants, we have investigated the effects of IMA, at realistic intestinal concentrations, on xenobiotic-metabolizing enzymes and efflux pumps by using Caco-2 cells, as a validated in vitro model of the human intestinal absorptive epithelium. For comparison, other conazole fungicides, i.e. ketoconazole, propiconazole and tebuconazole, were also studied. IMA induced cytochrome P450 (CYP) 1A1 activity to the same extent as benzo(a)pyrene (B(a)P) or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), in a dose- and time-dependent manner. Cell-free aryl hydrocarbon receptor (AhR) binding assay and reporter gene assay suggested that IMA is not an AhR-ligand, implying that IMA-mediated induction should involve an AhR-independent pathway. Moreover, IMA strongly inhibited the CYP3A4 activity in 1,25-vitamin D(3)-induced Caco-2 cells. The other fungicides had weak or nil effects on CYP activities. Study of the apical efflux pump activities revealed that ketoconazole inhibited both P-glycoprotein (Pgp) and multidrug resistance-associated protein 2 (MRP-2) or breast cancer resistance protein (BCRP), whereas IMA and other fungicides did not. Our results imply that coingestion of IMA-contaminated food and CYP3A4- or CYP1A1-metabolizable drugs or chemicals could lead to drug bioavailability modulation or toxicological interactions, with possible adverse effects for human health.

Software-Defined Avionics and Mission Systems in Future Vertical Lift Aircraft

DTIC Science & Technology

2015-03-01

military rotorcraft in the service of the United States Joint services have yet to benefit significantly from this technology. At long last, that may...Despite the demonstrated success of IMA systems in commercial airliners such as the Airbus A380 and the Boeing 787, military rotorcraft in the...8 4. Integrated Modular Avionics (IMA) – Generation One ..................9 5. Military IMA

Occupational Conversion Index: Enlisted/Officer/Civilian

DTIC Science & Technology

1993-09-01

14A/B OMA Integrated Weapons Technician AT 7975 APQ-126 FLR IMA Technician AT 7976 C-8!85 ASCU IMA Tecnnician AT 7978 APM-446 Radar System Test...Operator/Maintainer AT 6705 CASS Test Station Inter Main, Calibratiort/Adv Maint Technician AT 7923 ASCU & Tactical Computer SSE IMA Technician...GENERAL ARMY 93F Field Artillery Meteorological Crewmember NAVY AG Aerographer’s Mate AG 7412 Analyst-Forecaster MARINE CORPS 0847 a Artillery

The binding interaction of imazapyr with cucurbit[n]uril (n = 6-8): Combined experimental and molecular modeling study

NASA Astrophysics Data System (ADS)

Mokhtar, Maali Saad; Suliman, FakhrEldin O.; Elbashir, Abdalla A.

2018-04-01

The inclusion complexes of imazapyr (IMA) with cucurbit[n]uril, CB[n] (n = 6-8), have been investigated. Fluorescence spectroscopy, MALDI-TOF, and 1HNMR were used to investigate and characterize the inclusion complexation of IMA and CB[n] in solutions. Whereas the solid state complexes have been characterized by Fourier transform infrared spectroscopy (FTIR), and powder X-ray diffraction (PXRD). IMA was found to form 1:1 complexes with CB[n] with association constants ranging from 5.80 × 102-2.65 × 103. The guest molecule IMA was found to encapsulate into the larger cavities of CB[7] and CB[8], whereas with CB[6] the molecule remains outside the cavity. Molecular dynamic (MD) simulations were used to follow the inclusion process at an atomistic level to study the mechanism and stability of inclusion. The results obtained showed that inclusion complexes of IMA with both CB[7] and CB[8] are highly stable in aqueous media, but the CB[6] smaller cavity size prohibited the formation of an inclusion complex with IMA. The results clearly show that in addition to hydrophobic effects the presence of hydrogen bonding has added greatly to the stability of these complexes.

The relationship between ischaemia-modified albumin and good coronary collateral circulation.

PubMed

Gök, Murat; Kundi, Harun; Kızıltunç, Emrullah; Topcuoglu, Canan; Ornek, Ender

2018-01-01

It is important to determine the grade of the coronary collateral circulation (CCC) in patients with stable coronary artery disease. In this study, we aimed to investigate the relationship between the ischaemia-modified albumin (IMA) level and good CCC. A total of 95 patients with coronary angiography and at least one epicardial coronary artery obstruction were included in the study. The Rentrop classification was used with CCC grading, where 0 and 1 were defined as poor collateral, and 2 and 3 were defined as good collateral. The IMA level of the patients was measured using an enzyme-linked immunosorbent assay (ELISA). The receiver-operating characteristic curve was used to show the sensitivity and specificity of IMA levels and the optimal cut-off value for predicting good CCC. The multiple logistic regression analysis revealed that the IMA level in the good CCC group was higher (p < 0.045). Conversely, the high-sensitivity C-reactive protein level was lower in the good CCC group (p < 0.023). We found an IMA cut-off value (4.7 ng/mL) that indicated good CCC level, and this shows good CCC with 70.2% sensitivity and 60.3% specificity. The IMA level could serve as a simple and useful predictor of well-developed CCC.

Ischemia modified albumin increase indicating cardiac damage after experimental subarachnoid hemorrhage

PubMed Central

2014-01-01

Background Cardiac complications are often developed after subarachnoid hemorrhage (SAH) and may cause sudden death of the patient. There are reports in the literature addressing ischemia modified albumin (IMA) as an early and useful marker in the diagnosis of ischemic heart events. The aim of this study is to evaluate serum IMA by using the albumin cobalt binding (ACB) test in the first, second, and seventh days of experimental SAH in rats. Twenty-eight Wistar albino rats were divided into four groups each consisting of seven animals. These were classified as control group, 1st, 2nd and 7th day SAH groups. SAH was done by transclival basilar artery puncture. Blood samples were collected under anesthesia from the left ventricles of the heart using the cardiac puncture method for IMA measurement. Histopathological examinations were performed on the heart and lung tissues. Albumin with by colorimetric, creatine kinase (CK), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) were determined on an automatic analyser using the enzymatic method. IMA using by ACB test was detected with spectrophotometer. Results Serum IMA (p = 0.044) in seventh day of SAH were higher compared to the control group. Total injury scores of heart and lung tissue, also myocytolysis at day 7 were significantly higher than control group (p = 0.001, p = 0.001, p = 0.001), day 1 (p = 0.001, p = 0.001, p = 0.001) and day 2 (p = 0.001, p = 0.007, p = 0.001). A positive correlation between IMA - myocytolysis (r = 0.48, p = 0.008), and between IMA – heart tissue total injury score (r = 0.41, p = 0.029) was found. Conclusion The results revealed that increased serum IMA may be related to myocardial stress after SAH. PMID:24564759

A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.

PubMed

Floris, Giuseppe; Wozniak, Agnieszka; Sciot, Raf; Li, Haifu; Friedman, Lori; Van Looy, Thomas; Wellens, Jasmien; Vermaelen, Peter; Deroose, Christophe M; Fletcher, Jonathan A; Debiec-Rychter, Maria; Schöffski, Patrick

2013-02-01

Oncogenic signaling in gastrointestinal stromal tumors (GIST) is sustained via PI3K/AKT pathway. We used a panel of six GIST xenograft models to assess efficacy of GDC-0941 as single agent or in combination with imatinib (IMA). Nude mice (n = 136) were grafted bilaterally with human GIST carrying diverse KIT mutations. Mice were orally dosed over four weeks, grouped as follows: (A) control; (B) GDC-0941; (C) imatinib, and (D) GDC+IMA treatments. Xenografts regrowth after treatment discontinuation was assessed in groups C and D for an additional four weeks. Tumor response was assessed by volume measurements, micro-PET imaging, histopathology, and immunoblotting. Moreover, genomic alterations in PTEN/PI3K/AKT pathway were evaluated. In all models, GDC-0941 caused tumor growth stabilization, inhibiting tumor cell proliferation, but did not induce apoptosis. Under GDC+IMA, profound tumor regression, superior to either treatment alone, was observed. This effect was associated with the best histologic response, a nearly complete proliferation arrest and increased apoptosis. Tumor regrowth assays confirmed superior activity of GDC+IMA over imatinib; in three of six models, tumor volume remained reduced and stable even after treatment discontinuation. A positive correlation between response to GDC+IMA and PTEN loss, both on gene and protein levels, was found. GDC+IMA has significant antitumor efficacy in GIST xenografts, inducing more substantial tumor regression, apoptosis, and durable effects than imatinib. Notably, after treatment withdrawal, tumor regression was sustained in tumors exposed to GDC+IMA, which was not observed under imatinib. Assessment of PTEN status may represent a useful predictive biomarker for patient selection.

Evaluation of MIh Scoring System in Diagnosis of Obstructive Sleep Apnea Syndrome.

PubMed

Xu, Qinxing; Du, Junwei; Ling, Xiaobo; Lu, Yangfei

2017-10-02

BACKGROUND The objective of the present study was to investigate whether the analysis of magnesium (Mg), high-sensitivity C-reactive protein (hsCRP), and ischemia-modified albumin (IMA) concentrations can be used as a non-invasive and convenient method for diagnosing obstructive sleep apnea syndrome (OSAS). MATERIAL AND METHODS After polysomnography, venous blood was collected from 33 patients with OSAS and 30 control individuals. Serum levels of Mg, hsCRP, and IMA were investigated. The relationship between these factors and apnea-hypopnea index (AHI) was analyzed using the Pearson correlation coefficient. The role of the factors was determined using a receiver operating characteristic (ROC) curve and multivariate logistic regression analysis. RESULTS The levels of hsCRP and IMA were significantly higher in patients with OSAS than in control subjects, while the levels of Mg were lower (P<0.05 for all). A significant correlation was noted between serum IMA (r=0.614; P<0.001) and hsCRP (r=0.453; P<0.001) levels and the AHI. The ROC showed that serum Mg (AUC=0.74(0.62-0.85)), hsCRP (AUC=0.77(0.65-0.87)), and IMA (AUC=0.78(0.66-0.87)) levels could be used as markers to diagnose OSAS. Moreover, our new model, MIh, which is obtained by multivariate analysis, yielded an AUC value of 0.93 (0.83-0.98). Continuous positive airway pressure (CPAP) treatment reversed the changes in the serum levels of Mg, hsCRP, and IMA. CONCLUSIONS Patients with OSAS show reduced serum Mg levels and elevated serum hsCRP and IMA levels. These observed alterations can be reversed by CPAP treatment. A novel model, named MIh, may be a promising tool for OSAS diagnosis.

Correlation Between Presence of imaA (HP0289) and Inflammation in H. pylori Infected Patients through Analysis of Bacterial DNA

NASA Astrophysics Data System (ADS)

Gupta, A.; Jain, S.

2012-12-01

The bacterium Helicobacter pylori inhabits the stomachs of nearly half of the world's human population, yet only a small fraction (20%) of those people are harmfully affected by the organism. Inflammation caused by the species often results in stomach ulcers or even cancer in these infected patients. Previous studies indicate that the uncharacterized H. pylori gene imaA (HP0289) may be responsible for suppressing this inflammation. Correlation between the intactness of the gene and inflammation levels in patients was determined through analysis of 105 DNA samples from H. pylori infected patients. Traditional PCR and gel electrophoresis techniques were used in the experimentation process. Primers including AC235, 5'imaARev, 3'imaAFor2446, 3'imaARevClinical, ureA637For, ureA637Rev, interFor1, interRev1, interFor2, and interRev2 were used to identify deletions in HP0289 in each DNA sample. The results from this analysis could allow for eventual remediation of the adverse effects of H. pylori.

A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice.

PubMed

Tamura, Kei; Inoue, Kaoru; Takahashi, Miwa; Matsuo, Saori; Kodama, Yukio; Yoshida, Midori

2016-01-01

To clarify the major pathway of liver tumor development induced by imazalil (IMA), an imidazole fungicide, male constitutive androstane receptor (CAR)-knockout (CARKO) and wild-type (WT) mice were treated with IMA at 500 ppm in the diet up to 27 weeks after initiation by diethylnitrosamine. After 27 weeks of treatment, neither altered foci nor adenomas were significantly increased in CARKO mice, whereas both eosinophilic altered foci and adenomas were increased in WT mice. After 4 or 13 weeks of IMA treatment, liver hypertrophy was observed at the tumor-inducible dose without differences among genotypes or durations. Analysis of hepatic drug metabolite enzymes, performed after administration of multiple doses during a 1-week period, indicated that pregnane X receptor might be involved in liver hypertrophy because IMA markedly elevated Cyp3a11 and Cyp2b10 expression levels in a dose-dependent manner in both genotypes. Our results demonstrated that the CAR pathway was the main mechanism of liver tumor development induced by IMA. The carcinogenic pathway was different from that of liver hypertrophy.

Multi-year residual activity of Arborjet's IMA-jet (imidacloprid 5% SL) against emerald ash borer [Agrilus planipennis Fairemaire (Coleoptera: Buprestidae)] in green ash (Fraxinus pennsylvanica Marsh) in Troy, MI.

Treesearch

Joseph J. Doccola; Peter M. Wild; Eric J. Bristol; Joseph Lojko; Xin Li

2007-01-01

In cooperative university studies, IMA-jet treated green ash were effectively protected for 2 years to date in Troy, MI against emerald ash borer (EAB). Trees were infested at the time of treatment, exhibiting epicormic sprouting and thinning canopies. Twenty trees were injected with IMA-jet alone or with a diluent to aid uptake and translocation within the vascular...

IMAS Pulse Tube Cooler Development and Testing

NASA Technical Reports Server (NTRS)

Ross, R.; Johnson, D.; Chan, C.; Nguyen, T.; Colbert, R.; Raab, J.

1998-01-01

An Integrated Multispectral Atmospheric Sounder (IMAS) cryocooler has been developed over the past two years for providing on the order of 0.5-watt cooling at 55K in a lightweight compact configuration.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, R.N.

One hundred and fifty patients with coronary artery disease (CAD), 14 (9.3%) of whom had coexisting peripheral vascular disease, underwent bilateral internal mammary arteriography to study the incidence and extent of atherosclerosis in these vessels. Significant atherosclerosis of the internal mammary arteries (IMAs) was present in three patients (2%), of whom one had coexisting peripheral vascular disease. Lesions in the IMAs were found either proximally, close to the origin or distally, around the terminal bifurcation. Six of the 14 patients with peripheral vascular disease (4% of total subjects) had significant atherosclerosis of the brachiocephalic arteries. Atherosclerotic involvement of the IMAmore » is very unusual and rarely interferes with the use of these vessels for coronary bypass. More common, however, is atherosclerosis of the subclavian arteries, a contraindication for IMA grafting if the lesion is proximal to the IMA origin.« less

[Application of Ischemia Modified Albumin for Acute Ischemic Heart Disease in Forensic Science].

PubMed

Wang, P; Zhu, Z L; Zhu, N; Yu, H; Yue, Q; Wang, X L; Feng, C M; Wang, C L; Zhang, G H

2017-10-01

To explore the application value and forensic significance of ischemia modified albumin （IMA） in pericardial fluid to diagnose sudden cardiac death. IMA level in pericardial fluid was detected in acute ischemic heart disease group （ n =36）, acute myocardial infarction group （ n =6）, cardiomyopathy group （ n =4） and control group （ n =15） by albumin cobalt binding method. The levels of IMA were compared among these groups. The best cut-off IMA value was estimated and the sensitivity and specificity of acute myocardial ischemia group was distinguished from control group by receiver operating characteristics （ROC） curve. The IMA level in acute ischemic heart disease group was significantly higher than that of control group （ P <0.05）. Compared with acute myocardial infarction group and cardiomyopathy group, the IMA level in acute ischemic heart disease group had no significant difference （ P >0.05）. The cut-off value for the identification of acute myocardial ischemia which obtained by ROC analysis was 40.65 U/mL. And the sensitivity and specificity for distinguishing acute ischemia cardiac disease was 60.0% and 80.5%, respectively. The IMA value in pericardial fluid can be a reference marker for the diagnosis of acute myocardial ischemia, which also can provide objective basis for the forensic identification of sudden cardiac death. Copyright© by the Editorial Department of Journal of Forensic Medicine

Preservation of the inferior mesenteric artery via laparoscopic sigmoid colectomy performed for diverticular disease: real benefit or technical challenge: a randomized controlled clinical trial.

PubMed

Masoni, Luigi; Mari, Francesco Saverio; Nigri, Giuseppe; Favi, Francesco; Gasparrini, Marcello; Dall'Oglio, Anna; Pindozzi, Fioralba; Pancaldi, Alessandra; Brescia, Antonio

2013-01-01

Defecatory disorders are very common complications after left hemicolectomy and anterior rectal resection. These disorders seem related primarily to colonic denervation after the resection. To evaluate the real benefits of inferior mesenteric artery (IMA) preservation via laparoscopic left hemicolectomy performed for diverticular disease in terms of reduced colonic denervation and improved postoperative intestinal functions, a randomized, single-blinded (patients) controlled clinical trial was conducted. From January 2004 to January 2010, patients with symptomatic diverticular disease and a surgical indication were enrolled in the study and randomly assigned to two treatment groups. The first group underwent laparoscopic left hemicolectomy, which preserved the IMA by sectioning the sigmoid arteries one by one near the colonic wall, In the second group, the IMA was sectioned immediately below the origin of left colic artery. Defecation disorders were assessed by anorectal manometry and by three questionnaires to evaluate constipation, incontinence, and quality of life 6 months after the intervention. A total of 107 patients were included in the study. The 54 patients with preserved IMA showed a statistically lower incidence of defecation disorders such as fragmented evacuations, alternating bowel function, constipation, and minor incontinence, as well as less lifestyle alteration than the 53 patients with the IMA sectioned just below the left colic artery. This study confirmed that preservation of the IMA should be recommended to reduce the incidence of defecatory disorders after left hemicolectomy for benign disease.

Program Solicitation for FY-1987 Defense Small Business Innovation Research Program (SBIR).

DTIC Science & Technology

1986-10-01

Which presents ballistic problems. A preferred design from a strictly performance point-of-view is the non -cased charge. However, this is not practical...the protection and onsuability of the combustible and the performance of the non -cased charge. It is required to develop a design which can accomplish...send data. Data bandwidths of 200 MHz are desirable. A97-91. TITLE: l11h Speed Non - olarizino Light Attenuator for Imaes DESCRIPTION. Design and

How Miniature/Microminiature (2M) Repair Capabilities Can Reduce the Impact of No Evidence of Failure (NEOF) Among Repairables on the Navy’s Operations and Maintenance Account

DTIC Science & Technology

1988-06-01

and PCBs. The pilot program involved screening, testing , and repairing of EMs/PCBs for both COMNAVSEASYSCOM and Commander, Naval Electronic Systems...were chosen from the Support and Test Equipment Engineering Program (STEEP) tests rformed by"IMA San Diego duringl987. A statistical analysis and a Level...were chosen from the Support and Test Equipment Engineering Program (STEEP) tests performed by SIMA San Diego during 1987. A statistical analysis and a

Mammography image quality and evidence based practice: Analysis of the demonstration of the inframammary angle in the digital setting.

PubMed

Spuur, Kelly; Webb, Jodi; Poulos, Ann; Nielsen, Sharon; Robinson, Wayne

2018-03-01

The aim of this study is to determine the clinical rates of the demonstration of the inframammary angle (IMA) on the mediolateral oblique (MLO) view of the breast on digital mammograms and to compare the outcomes with current accreditation standards for compliance. Relationships between the IMA, age, the posterior nipple line (PNL) and compressed breast thickness will be identified and the study outcomes validated using appropriate analyses of inter-reader and inter-rater reliability and variability. Differences in left versus right data were also investigated. A quantitative retrospective study of 2270 randomly selected paired digital mammograms performed by BreastScreen NSW was undertaken. Data was collected by direct measurement and visual analysis. Intra-class correlation analyses were used to evaluate inter- and intra-rater reliability. The IMA was demonstrated on 52.4% of individual and 42.6% of paired mammograms. A linear relationship was found between the posterior nipple line (PNL) and age (p-value <0.001). The PNL was predicted to increase by 0.48 mm for every one year increment in age. The odds of demonstrating the IMA reduced by 2% for every one year increase in age (p-value = 0.001); are 0.4% higher for every 1 mm increase in PNL (p-value = 0.001) and 1.6% lower for every 1 mm increase in compressed breast thickness, (p-value<0.001). There was high inter- and intra-rater reliability for the PNL while there was 100% agreement for the demonstration of the IMA. Analysis of the demonstration of the IMA indicates clinically achievable rates (42.6%) well below that required for compliance (50%-75%) to known worldwide accreditation standards for screening mammography. These standards should be aligned to the reported evidence base. Visualisation of the IMA is impacted negatively by increasing age and compressed breast thickness but positively by breast size (PNL). Copyright © 2018 Elsevier B.V. All rights reserved.

Early and late outcome of skeletonised bilateral internal mammary arteries anastomosed to the left coronary system.

PubMed

Bonacchi, M; Battaglia, F; Prifti, E; Leacche, M; Nathan, N S; Sani, G; Popoff, G

2005-02-01

To investigate in a retrospective study the technical aspects of using the in situ bilateral internal mammary arteries (IMAs), with the right IMA (RIMA) used for revascularisation of the circumflex system, and to evaluate early and late outcome. Between January 1997 and July 2003, 552 consecutive patients underwent grafting of the circumflex artery system with an in situ skeletonised RIMA routed through the transverse sinus (eventually retrocaval). Mean (SD) age was 63.8 (11) years. 331 (60%) patients underwent total arterial myocardial revascularisation. Mean follow up was 26 (9) months. The success rate of skeletonised RIMA grafting to the circumflex branch was 100%. There were 19 (3.4%) in-hospital deaths. Perioperative myocardial infarction occurred in 12 (2.2%) patients. In 155 patients undergoing postoperative angiography, two had an occluded RIMA and a string-like phenomenon was seen in three RIMA and one left IMA (LIMA). Three RIMA and three LIMA had stenotic lesions. The patency rates of RIMA and LIMA were 94% and 97.4%, respectively. Strong predictors of non-functional IMA grafts were a recipient coronary artery diameter of < 1.5 mm (p = 0.022), < 60% stenosis of the recipient coronary artery (p = 0.015), diffuse stenotic lesions of the recipient coronary artery (p = 0.018), and a small IMA calibre (p = 0.0001). Cumulative actuarial survival at three years was 96.4% and event-free cumulative survival was 93.8%. Use of the bilateral IMAs offers the possibility of constructing various configurations, making total arterial myocardial revascularisation possible with a minimum number of arterial conduits. Use of the skeletonised RIMA through the transverse sinus and eventually retrocavally can reach most branches of the circumflex system and is associated with an excellent patency rate. Patients who received bilateral IMA grafts for left coronary system revascularisation had improved early and late outcomes and decreased risk of death, reoperation, and angioplasty.

IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial.

PubMed

Rini, Brian I; Stenzl, Arnulf; Zdrojowy, Romauld; Kogan, Mikhail; Shkolnik, Mikhail; Oudard, Stephane; Weikert, Steffen; Bracarda, Sergio; Crabb, Simon J; Bedke, Jens; Ludwig, Joerg; Maurer, Dominik; Mendrzyk, Regina; Wagner, Claudia; Mahr, Andrea; Fritsche, Jens; Weinschenk, Toni; Walter, Steffen; Kirner, Alexandra; Singh-Jasuja, Harpreet; Reinhardt, Carsten; Eisen, Tim

2016-11-01

In a phase 2 study in patients with metastatic renal cell carcinoma, overall survival was associated with T-cell responses against IMA901, a vaccine consisting of ten tumour-associated peptides. In this phase 3 trial, we aimed to determine the clinical effect of adding IMA901 to sunitinib, the standard first-line treatment in metastatic renal cell carcinoma with postulated favourable immunomodulatory effects. The IMPRINT study is an open-label, randomised, controlled, phase 3 trial done at 124 clinical sites in 11 countries. HLA-A*02-positive patients (aged ≥18 years) with treatment-naive, histologically confirmed metastatic or locally advanced (or both) clear-cell renal cell carcinoma were randomly assigned (3:2) to receive sunitinib plus up to ten intradermal vaccinations of IMA901 (4·13 mg) and granulocyte macrophage colony-stimulating factor (75 μg), with one dose of cyclophosphamide (300 mg/m 2 ) 3 days before the first vaccination, or to receive sunitinib alone. Sunitinib (50 mg) was given orally once daily, with each cycle defined as 4 weeks on treatment followed by 2 weeks off treatment, until progression of disease as determined by the investigator, death, or withdrawal of consent. Block randomisation (block size five) was done centrally using an interactive web response system, stratified by prognostic risk, geographical region, and previous nephrectomy. Patients and investigators were not masked to treatment allocation. The primary endpoint was overall survival from randomisation until death of any cause as determined by the investigator, analysed by intention to treat. This study is registered with ClinicalTrials.gov, number NCT01265901. Between Dec 22, 2010, and Dec 15, 2012, we screened 1171 patients, of whom 339 were randomly assigned to receive sunitinib plus IMA901 (n=204) or sunitinib monotherapy (n=135). Patients had a median follow-up of 33·27 months (IQR 29·92-35·64). Median overall survival did not differ significantly between the groups (33·17 months [95% CI 27·81-41·36] in the sunitinib plus IMA901 group vs not reached [33·67-not reached] in the sunitinib monotherapy group; hazard ratio 1·34 [0·96-1·86]; p=0·087). 116 (57%) of 202 patients in the sunitinib plus IMA901 group and 62 (47%) of 132 in the sunitinib group had grade 3 or worse adverse events, the most common of which were hypertension, neutropenia, and anaemia in both groups, and mild-to-moderate transient injection-site reactions (eg, erythema, pruritus) were the most frequent IMA901-related side-effect in the sunitinib plus IMA901 group. Serious adverse events leading to death occurred in four (2%) patients (one respiratory failure and circulatory collapse [possibly related to sunitinib], one oesophageal varices haemorrhage [possibly related to sunitinib], one cardiac arrest [possibly related to sunitinib], and one myocardial infarction) and eight (6%) patients in the sunitinib group (one case each of renal failure, oesophageal varices haemorrhage, circulatory collapse, wound infection, ileus, cerebrovascular accident [possibly treatment related], and sepsis). IMA901 did not improve overall survival when added to sunitinib as first-line treatment in patients with metastatic renal cell carcinoma. The magnitude of immune responses needs to be improved before further development of IMA901 in this disease is indicated. Immatics Biotechnologies. Copyright © 2016 Elsevier Ltd. All rights reserved.

Capability of ischemia-modified albumin to predict serious cardiac outcomes in the short term among patients with potential acute coronary syndrome.

PubMed

Worster, Andrew; Devereaux, P J; Heels-Ansdell, Diane; Guyatt, Gordon H; Opie, John; Mookadam, Farouk; Hill, Stephen A

2005-06-21

Ischemia-modified albumin (IMA) has been suggested as a marker of cardiac ischemia. Little, however, is known about its capacity to predict short-term serious cardiac outcomes (death, myocardial infarction, congestive heart failure, serious arrhythmia, or refractory ischemic cardiac pain) in patients arriving at the emergency department with symptoms that may indicate cardiac ischemia. We screened 546 patients over a 4-week period, of whom 189 fulfilled our entry criteria by presenting to an emergency department with potential cardiac-ischemia symptoms within 6 hours after chest pain, seeing an emergency physician who chose to order a troponin I test, and having no serious cardiac outcome before the troponin result became available. We followed the study patients for 72 hours to determine if any experienced a serious cardiac outcome. We calculated the likelihood ratios (LRs) of IMA findings predicting serious cardiac outcomes that could not be diagnosed at presentation with current techniques. Of the 189 patients, 24 had a serious cardiac outcome within 72 hours after their arrival at the emergency department. The likelihood ratios for IMA measurement within 6 hours after chest pain predicting a serious cardiac outcome within the next 72 hours were 1.35 (95% confidence interval [CI] 0.315-5.79) for IMA < or = 80 U/mL and 0.98 (95% CI 0.86- 1.11) for IMA > 80 U/mL. These data suggest that in patients presenting with chest pain who have not yet experienced a serious cardiac event, IMA is a poor predictor of serious cardiac outcomes in the short term.

Ambient iron-mediated aeration (IMA) for water reuse.

PubMed

Deng, Yang; Englehardt, James D; Abdul-Aziz, Samer; Bataille, Tristan; Cueto, Josenrique; De Leon, Omar; Wright, Mary E; Gardinali, Piero; Narayanan, Aarthi; Polar, Jose; Tomoyuki, Shibata

2013-02-01

Global water shortages caused by rapidly expanding population, escalating water consumption, and dwindling water reserves have rendered water reuse a strategically significant approach to meet current and future water demand. This study is the first to our knowledge to evaluate the technical feasibility of iron-mediated aeration (IMA), an innovative, potentially economical, holistic, oxidizing co-precipitation process operating at room temperature, atmospheric pressure, and neutral pH, for water reuse. In the IMA process, dissolved oxygen (O₂) was continuously activated by zero-valent iron (Fe⁰) to produce reactive oxygen species (ROS) at ambient pH, temperature, and pressure. Concurrently, iron sludge was generated as a result of iron corrosion. Bench-scale tests were conducted to study the performance of IMA for treatment of secondary effluent, natural surface water, and simulated contaminated water. The following removal efficiencies were achieved: 82.2% glyoxylic acid, ~100% formaldehyde as an oxidation product of glyoxylic acid, 94% of Ca²⁺ and associated alkalinity, 44% of chemical oxygen demand (COD), 26% of electrical conductivity (EC), 98% of di-n-butyl phthalate (DBP), 80% of 17β-estradiol (E2), 45% of total nitrogen (TN), 96% of total phosphorus (TP), 99.8% of total Cr, >90% of total Ni, 99% of color, 3.2 log removal of total coliform, and 2.4 log removal of E. Coli. Removal was attributed principally to chemical oxidation, precipitation, co-precipitation, coagulation, adsorption, and air stripping concurrently occurring during the IMA treatment. Results suggest that IMA is a promising treatment technology for water reuse. Copyright © 2012 Elsevier Ltd. All rights reserved.

Effect of chronic regular exercise on serum ischemia-modified albumin levels and oxidative stress in type 2 diabetes mellitus.

PubMed

Kurban, Sevil; Mehmetoglu, Idris; Yerlikaya, Hümeyra F; Gönen, Sait; Erdem, Sami

2011-01-01

Objectives. Our aim was to determine the effect of chronic regular exercise on ischemia-modified albumin (IMA) levels and oxidative stress in type 2 diabetes mellitus (DM). Design and methods. Sixty patients with type 2 DM were randomly divided into two groups as exercise (17 M, 13 F) and non-exercise (12 M, 18 F) groups, each consisting of 30 patients. The exercise group underwent a 3-month aerobic regular exercise consisting of moderate-intensity power walking. The non-exercise subjects remained sedentary throughout the study period. Serum total antioxidant status (TAS), total oxidant status (TOS), and IMA levels of the groups were determined at baseline and 3 months later. Results. There was no significant change in TOS and IMA levels of exercise group but TAS levels were significantly increased (p < 0.05). Also, postexercise systolic (p < 0.001) and diastolic (p < 0.05) blood pressures of the exercise group were significantly lower than the baseline values. In addition, there was no significant change in TAS and TOS levels of the non-exercise group; however, IMA levels were significantly increased (p < 0.01). Conclusion. We have shown, for the first time, that exercise prevents increase in IMA levels in type 2 DM which might have resulted from increased levels of TAS and reduces the risk of ischemia in these patients. These findings show that chronic exercise is beneficial in the prevention of oxidative stress in patients with type 2 DM as documented by decreased IMA levels.

Total oxidant status, total antioxidant capacity and ischemia modified albumin levels in children with celiac disease.

PubMed

Sayar, Ersin; Özdem, Sebahat; Uzun, Gülbahar; İşlek, Ali; Yılmaz, Aygen; Artan, Reha

2015-01-01

In our study, we aimed to investigate ischemia modified albumin (IMA) as an oxidative stress marker, as well as other oxidant and antioxidant markers that have not been evaluated in children with celiac disease. A total of 37 pediatric patients who were diagnosed with celiac disease (CD) and 29 healthy children were enrolled in this prospective study. We evaluated the IMA, total oxidant status, total antioxidant capacity, sulfhydryl, and advanced oxidation protein products in all of the subjects. We also compared the levels at the time of the diagnosis, and following a gluten-free diet (GFD) in the children with CD. While the IMA and the other oxidant marker levels were significantly higher in the patient group compared to the control group, the antioxidant marker levels were found to be significantly lower in the patient group, compared to the control group. We also determined that the tissue transglutaminase IgA showed a highly positive correlation, and that the IMA showed a moderately positive correlation with the Marsh-Oberhuber histopathological stage. Additionally, the IMA and other oxidant marker levels were significantly lower, while the antioxidant marker levels were significantly higher after the GFD, compared to the pre-diet period. We detected that oxidative stress played a role in the pathogenesis of CD, and that this could be evaluated using oxidative stress markers, which would regress after the GFD. We also detected that IMA is a marker that shows a correlation with the histopathological stage, and may be used in the diagnosis.

Image microarrays (IMA): Digital pathology's missing tool

PubMed Central

Hipp, Jason; Cheng, Jerome; Pantanowitz, Liron; Hewitt, Stephen; Yagi, Yukako; Monaco, James; Madabhushi, Anant; Rodriguez-canales, Jaime; Hanson, Jeffrey; Roy-Chowdhuri, Sinchita; Filie, Armando C.; Feldman, Michael D.; Tomaszewski, John E.; Shih, Natalie NC.; Brodsky, Victor; Giaccone, Giuseppe; Emmert-Buck, Michael R.; Balis, Ulysses J.

2011-01-01

Introduction: The increasing availability of whole slide imaging (WSI) data sets (digital slides) from glass slides offers new opportunities for the development of computer-aided diagnostic (CAD) algorithms. With the all-digital pathology workflow that these data sets will enable in the near future, literally millions of digital slides will be generated and stored. Consequently, the field in general and pathologists, specifically, will need tools to help extract actionable information from this new and vast collective repository. Methods: To address this limitation, we designed and implemented a tool (dCORE) to enable the systematic capture of image tiles with constrained size and resolution that contain desired histopathologic features. Results: In this communication, we describe a user-friendly tool that will enable pathologists to mine digital slides archives to create image microarrays (IMAs). IMAs are to digital slides as tissue microarrays (TMAs) are to cell blocks. Thus, a single digital slide could be transformed into an array of hundreds to thousands of high quality digital images, with each containing key diagnostic morphologies and appropriate controls. Current manual digital image cut-and-paste methods that allow for the creation of a grid of images (such as an IMA) of matching resolutions are tedious. Conclusion: The ability to create IMAs representing hundreds to thousands of vetted morphologic features has numerous applications in education, proficiency testing, consensus case review, and research. Lastly, in a manner analogous to the way conventional TMA technology has significantly accelerated in situ studies of tissue specimens use of IMAs has similar potential to significantly accelerate CAD algorithm development. PMID:22200030

An efficient computational approach to model statistical correlations in photon counting x-ray detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faby, Sebastian; Maier, Joscha; Sawall, Stefan

2016-07-15

Purpose: To introduce and evaluate an increment matrix approach (IMA) describing the signal statistics of energy-selective photon counting detectors including spatial–spectral correlations between energy bins of neighboring detector pixels. The importance of the occurring correlations for image-based material decomposition is studied. Methods: An IMA describing the counter increase patterns in a photon counting detector is proposed. This IMA has the potential to decrease the number of required random numbers compared to Monte Carlo simulations by pursuing an approach based on convolutions. To validate and demonstrate the IMA, an approximate semirealistic detector model is provided, simulating a photon counting detector inmore » a simplified manner, e.g., by neglecting count rate-dependent effects. In this way, the spatial–spectral correlations on the detector level are obtained and fed into the IMA. The importance of these correlations in reconstructed energy bin images and the corresponding detector performance in image-based material decomposition is evaluated using a statistically optimal decomposition algorithm. Results: The results of IMA together with the semirealistic detector model were compared to other models and measurements using the spectral response and the energy bin sensitivity, finding a good agreement. Correlations between the different reconstructed energy bin images could be observed, and turned out to be of weak nature. These correlations were found to be not relevant in image-based material decomposition. An even simpler simulation procedure based on the energy bin sensitivity was tested instead and yielded similar results for the image-based material decomposition task, as long as the fact that one incident photon can increase multiple counters across neighboring detector pixels is taken into account. Conclusions: The IMA is computationally efficient as it required about 10{sup 2} random numbers per ray incident on a detector pixel instead of an estimated 10{sup 8} random numbers per ray as Monte Carlo approaches would need. The spatial–spectral correlations as described by IMA are not important for the studied image-based material decomposition task. Respecting the absolute photon counts and thus the multiple counter increases by a single x-ray photon, the same material decomposition performance could be obtained with a simpler detector description using the energy bin sensitivity.« less

Role of ischemic modified albumin in the early diagnosis of increased intracranial pressure and brain death.

PubMed

Kara, I; Pampal, H K; Yildirim, F; Dilekoz, E; Emmez, G; U, F P; Kocabiyik, M; Demirel, C B

Increased intracranial pressure following trauma and subsequent possible development of brain death are important factors for morbidity and mortality due to ischemic changes. We aimed to establish the role of ischemic modified albumin (IMA) in the early diagnosis of the process, starting with increased intracranial pressure and ending with brain death. Eighteen Wistar-Albino rats were divided into three groups; control (CG, n = 6), increased intracranial pressure (ICPG, n = 6), and brain death (BDG, n = 6). Intracranial pressure elevation and brain death were constituted with the inflation of a balloon of a Fogarty catheter in the epidural space. In all three groups, blood samples were drawn before the procedure, and at minutes 150 and 240 for IMA and malondialdehyde (MDA) analysis. Serum IMA levels at 150 and 240 minutes were higher in ICPG than in CG (p < 0.05). IMA levels were similar in ICPG and BDG. Serum MDA levels at 150 and 240 minutes increased in ICPG and BDG groups compared to CG (p < 0.05). MDA levels were similar in ICP and BD groups. IMA should be considered as a biochemical parameter in the process starting from increased intracranial pressure elevation and ending at brain death (Tab. 3, Fig. 5, Ref. 31).

K→(ππ)(I=2) decay amplitude from lattice QCD.

PubMed

Blum, T; Boyle, P A; Christ, N H; Garron, N; Goode, E; Izubuchi, T; Jung, C; Kelly, C; Lehner, C; Lightman, M; Liu, Q; Lytle, A T; Mawhinney, R D; Sachrajda, C T; Soni, A; Sturm, C

2012-04-06

We report on the first realistic ab initio calculation of a hadronic weak decay, that of the amplitude A(2) for a kaon to decay into two π mesons with isospin 2. We find ReA(2)=(1.436±0.063(stat)±0.258(syst))10(-8) GeV in good agreement with the experimental result and for the hitherto unknown imaginary part we find ImA(2)=-(6.83±0.51(stat)±1.30(syst))10(-13) GeV. Moreover combining our result for ImA(2) with experimental values of ReA(2), ReA(0), and ε'/ε, we obtain the following value for the unknown ratio ImA(0)/ReA(0) within the standard model: ImA(0)/ReA(0)=-1.63(19)(stat)(20(syst)×10(-4). One consequence of these results is that the contribution from ImA(2) to the direct CP violation parameter ε' (the so-called Electroweak Penguin contribution) is Re(ε'/ε)(EWP)=-(6.52±0.49(stat)±1.24(syst))×10(-4). We explain why this calculation of A(2) represents a major milestone for lattice QCD and discuss the exciting prospects for a full quantitative understanding of CP violation in kaon decays. © 2012 American Physical Society

K → ( π π ) I = 2 Decay Amplitude from Lattice QCD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blum, T.; Boyle, P. A.; Christ, N. H.

2012-04-04

We report on the first realistic ab initio calculation of a hadronic weak decay, that of the amplitude A 2 for a kaon to decay into two π mesons with isospin 2. We find ReA 2=(1.436±0.063 stat±0.258 syst)10 -8 GeV in good agreement with the experimental result and for the hitherto unknown imaginary part we find ImA 2=-(6.83±0.51 stat±1.30 syst)10 -13 GeV. Moreover combining our result for ImA 2 with experimental values of ReA 2, ReA0, and ϵ'/ϵ, we obtain the following value for the unknown ratio ImA 0/ReA 0 within the standard model: ImA 0/ReA 0=-1.63(19) stat(20) syst×10 -4.more » One consequence of these results is that the contribution from ImA 2 to the direct CP violation parameter ϵ' (the so-called Electroweak Penguin contribution) is Re(ϵ'/ϵ)EWP=-(6.52±0.49 stat±1.24 syst)×10 -4. We explain why this calculation of A 2 represents a major milestone for lattice QCD and discuss the exciting prospects for a full quantitative understanding of CP violation in kaon decays.« less

Characterization of a new multigene family encoding isomaltases in the yeast Saccharomyces cerevisiae, the IMA family.

PubMed

Teste, Marie-Ange; François, Jean Marie; Parrou, Jean-Luc

2010-08-27

It has been known for a long time that the yeast Saccharomyces cerevisiae can assimilate alpha-methylglucopyranoside and isomaltose. We here report the identification of 5 genes (YGR287c, YIL172c, YJL216c, YJL221c and YOL157c), which, similar to the SUCx, MALx, or HXTx multigene families, are located in the subtelomeric regions of different chromosomes. They share high nucleotide sequence identities between themselves (66-100%) and with the MALx2 genes (63-74%). Comparison of their amino acid sequences underlined a substitution of threonine by valine in region II, one of the four highly conserved regions of the alpha-glucosidase family. This change was previously shown to be sufficient to discriminate alpha-1,4- to alpha-1,6-glucosidase activity in YGR287c (Yamamoto, K., Nakayama, A., Yamamoto, Y., and Tabata, S. (2004) Eur. J. Biochem. 271, 3414-3420). We showed that each of these five genes encodes a protein with alpha-glucosidase activity on isomaltose, and we therefore renamed these genes IMA1 to IMA5 for IsoMAltase. Our results also illustrated that sequence polymorphisms among this family led to interesting variability of gene expression patterns and of catalytic efficiencies on different substrates, which altogether should account for the absence of functional redundancy for growth on isomaltose. Indeed, deletion studies revealed that IMA1/YGR287c encodes the major isomaltase and that growth on isomaltose required the presence of AGT1, which encodes an alpha-glucoside transporter. Expressions of IMA1 and IMA5/YJL216c were strongly induced by maltose, isomaltose, and alpha-methylglucopyranoside, in accordance with their regulation by the Malx3p-transcription system. The physiological relevance of this IMAx multigene family in S. cerevisiae is discussed.

Use of the iPhone for radiographic evaluation of hallux valgus.

PubMed

Ege, Tolga; Kose, Ozkan; Koca, Kenan; Demiralp, Bahtiyar; Basbozkurt, Mustafa

2013-02-01

The purpose of this study was to compare the measurements made using a smartphone accelerometer and computerized measurements as a reference in a series of 32 hallux valgus patients. Two observers used an iPhone to measure the hallux valgus angle (HVA), intermetatarsal angle (IMA), and distal metatarsal articular angle (of anteroposterior foot radiographs in 32 patients with symptomatic hallux valgus on a computer screen. Digital angular measurements on the computer were set as the reference standard for analysis and comparison. The difference between computerized measurements and all iPhone measurements, and the difference between the first and second iPhone measurements for each observer were calculated. Inter- and intraobserver reliability of the smartphone measurement method was also tested. The variability of all measurements was similar for the iPhone and the computer-assisted techniques. The concordance between iPhone and computer-assisted angular measurements was excellent for the HVA, IMA, and DMAA. The maximum mean difference between the two techniques was 1.25 ± 1.02° for HVA, 0.92 ± 0.92° for IMA, and 1.10 ± 0.82° for DMAA. The interobserver reliability was excellent for HVA, IMA, and DMAA. The maximum mean difference between observers was 1.31 ± 0.89° for HVA, 0.90 ± 0.92° for IMA, and 0.78 ± 0.87° for DMAA. The intraobserver reliability was excellent for HVA, IMA, and DMAA. We conclude that the Hallux Angles software for the iPhone can be used for measurement of hallux valgus angles in clinical practice and even for research purposes. It is an accurate and reproducible method.

NPS Government Purchase Card Program: An Analysis of Internal Controls

DTIC Science & Technology

2014-03-18

Management Division CH Cardholder COSO Committee of Sponsoring Organization of the Treadway Commission CNO Chief of Naval Operations DAU Defense...2). To minimize risks , the management and internal controls should have support from higher levels, expect integrity and ethical behavior from...Financial Executives International (FEI); The Institute of Management Accountants (IMA); and the Institute of Internal Auditors (IIA; COSO , n.d.-b

On the occurrence of false positives in tests of migration under an isolation with migration model

PubMed Central

Hey, Jody; Chung, Yujin; Sethuraman, Arun

2015-01-01

The population genetic study of divergence is often done using a Bayesian genealogy sampler, like those implemented in IMa2 and related programs, and these analyses frequently include a likelihood-ratio test of the null hypothesis of no migration between populations. Cruickshank and Hahn (2014, Molecular Ecology, 23, 3133–3157) recently reported a high rate of false positive test results with IMa2 for data simulated with small numbers of loci under models with no migration and recent splitting times. We confirm these findings and discover that they are caused by a failure of the assumptions underlying likelihood ratio tests that arises when using marginal likelihoods for a subset of model parameters. We also show that for small data sets, with little divergence between samples from two populations, an excellent fit can often be found by a model with a low migration rate and recent splitting time and a model with a high migration rate and a deep splitting time. PMID:26456794

Intermediate-dose cytarabine plus mitoxantrone versus standard-dose cytarabine plus daunorubicin for acute myeloid leukemia in elderly patients.

PubMed

Röllig, C; Kramer, M; Gabrecht, M; Hänel, M; Herbst, R; Kaiser, U; Schmitz, N; Kullmer, J; Fetscher, S; Link, H; Mantovani-Löffler, L; Krümpelmann, U; Neuhaus, T; Heits, F; Einsele, H; Ritter, B; Bornhäuser, M; Schetelig, J; Thiede, C; Mohr, B; Schaich, M; Platzbecker, U; Schäfer-Eckart, K; Krämer, A; Berdel, W E; Serve, H; Ehninger, G; Schuler, U S

2018-04-01

The combination of intermediate-dose cytarabine plus mitoxantrone (IMA) can induce high complete remission rates with acceptable toxicity in elderly patients with acute myeloid leukemia (AML). We present the final results of a randomized-controlled trial comparing IMA with the standard 7 + 3 induction regimen consisting of continuous infusion cytarabine plus daunorubicin (DA). Patients with newly diagnosed AML >60 years were randomized to receive either intermediate-dose cytarabine (1000 mg/m2 twice daily on days 1, 3, 5, 7) plus mitoxantrone (10 mg/m2 days 1-3) (IMA) or standard induction therapy with cytarabine (100 mg/m2 continuously days 1-7) plus daunorubicin (45 mg/m2 days 3-5) (DA). Patients in complete remission after DA received intermediate-dose cytarabine plus amsacrine as consolidation treatment, whereas patients after IMA were consolidated with standard-dose cytarabine plus mitoxantrone. Between February 2005 and October 2009, 485 patients were randomized; 241 for treatment arm DA and 244 for IMA; 76% of patients were >65 years. The complete response rate after DA was 39% [95% confidence interval (95% CI): 33-45] versus 55% (95% CI: 49-61) after IMA (odds ratio 1.89, P = 0.001). The 6-week early-death rate was 14% in both arms. Relapse-free survival curves were superimposable in the first year, but separated afterwards, resulting in 3-year relapse-free survival rates of 29% versus 14% in the DA versus IMA arms, respectively (P = 0.042). The median overall survival was 10 months in both arms (P = 0.513). The dose escalation of cytarabine in induction therapy lead to improved remission rates in the elderly AML patients. This did not translate into a survival advantage, most likely due to differences in consolidation treatment. Thus, effective consolidation strategies need to be further explored. In combination with an effective consolidation strategy, the use of intermediate-dose cytarabine in induction may improve curative treatment for elderly AML patients.

Quality DOTS management and empowering tuberculosis patients.

PubMed

Chugh, Satish

2009-03-01

Central Tuberculosis Division (CTD) has covered whole of India under DOTS. IMA is a proud partner of RNTCP which is managed by CTD. International Standards for Tuberculosis Care is expected from all healthcare providers. The basic principles of care is same worldwide. IMA GFATM RNTCP PPM is completing 2 years of its inception. Sensitisation programme and district training programmes has yielded DOTS/DMC centres in the target states. IMA is having 100% commitment for containing tuberculosis in India. There are International Standards for quality management in tuberculosis control, some of the Standards are elaborated in this write-up. In the Indian context, DOTS needs some innovations that is discussed in this article.

Automatic design of IMA systems

NASA Astrophysics Data System (ADS)

Salomon, U.; Reichel, R.

During the last years, the integrated modular avionics (IMA) design philosophy became widely established at aircraft manufacturers, giving rise to a series of new design challenges, most notably the allocation of avionics functions to the various IMA components and the placement of this equipment in the aircraft. This paper presents a modelling approach for avionics that allows automation of some steps of the design process by applying an optimisation algorithm which searches for system configurations that fulfil the safety requirements and have low costs. The algorithm was implemented as a quite sophisticated software prototype, therefore we will also present detailed results of its application to actual avionics systems.

Improving students’ mathematical critical thinking through rigorous teaching and learning model with informal argument

NASA Astrophysics Data System (ADS)

Hamid, H.

2018-01-01

The purpose of this study is to analyze an improvement of students’ mathematical critical thinking (CT) ability in Real Analysis course by using Rigorous Teaching and Learning (RTL) model with informal argument. In addition, this research also attempted to understand students’ CT on their initial mathematical ability (IMA). This study was conducted at a private university in academic year 2015/2016. The study employed the quasi-experimental method with pretest-posttest control group design. The participants of the study were 83 students in which 43 students were in the experimental group and 40 students were in the control group. The finding of the study showed that students in experimental group outperformed students in control group on mathematical CT ability based on their IMA (high, medium, low) in learning Real Analysis. In addition, based on medium IMA the improvement of mathematical CT ability of students who were exposed to RTL model with informal argument was greater than that of students who were exposed to CI (conventional instruction). There was also no effect of interaction between RTL model and CI model with both (high, medium, and low) IMA increased mathematical CT ability. Finally, based on (high, medium, and low) IMA there was a significant improvement in the achievement of all indicators of mathematical CT ability of students who were exposed to RTL model with informal argument than that of students who were exposed to CI.

Posture Recognition in Alzheimer's Disease

ERIC Educational Resources Information Center

Mozaz, Maria; Garaigordobil, Maite; Rothi, Leslie J. Gonzalez; Anderson, Jeffrey; Crucian, Gregory P.; Heilman, Kenneth M.

2006-01-01

Background: Apraxia is neurologically induced deficit in the ability perform purposeful skilled movements. One of the most common forms is ideomotor apraxia (IMA) where spatial and temporal production errors are most prevalent. IMA can be associated Alzheimer's disease (AD), even early in its course, but is often not identified possibly because…

Concomitant aortic valve and internal mammary artery injuries in blunt chest trauma: report of a case.

PubMed

Yeh, Chun-Chieh; Hsieh, Chi-Hsun; Wang, Yu-Chun; Chung, Ping-Kuei; Chen, Ray-Jade

2009-01-01

We report a case of concomitant injury to the aortic valve and internal mammary artery (IMA) from nonpenetrating chest trauma. To our knowledge, this is the first such case to be reported. Transcatheter arterial embolization (TAE) following diagnostic angiography offers an effective and minimally invasive treatment for traumatic IMA injuries. Because there might be an asymptomatic interval after traumatic aortic valve injuries, serial physical examinations and repeated echocardiography should be mandatory for patients with de novo heart failure after blunt chest trauma. Transesophageal echocardiography can provide a clearer image of cardiac injuries than transthoracic echocardiography, particularly if there is extensive anterior mediastinal hematoma resulting from IMA trauma.

Opening the pleura during internal mammary artery harvesting: advantages and disadvantages

PubMed Central

Ali, Idris M.; Lau, Peter; Kinley, C. Edwin; Sanalla, Abulkasim

1996-01-01

Objective To evaluate the findings of previous studies that opening of the pleura during internal mammary artery (IMA) dissection might be an important factor in increasing the operative morbidity. Design A randomized control trial. Setting A university hospital. Patients Two hundred and eighty consecutive patients with no significant pulmonary disease. Intervention Harvesting of the IMA with (130 patients) or without (150 patients) opening the pleura. Main Outcome Measures Comparison of the incidence of pleural effusion, cardiac tamponade, postoperative respiratory complications and the hospital stay. Results Pleural effusion occurred more often in the patients who had opening of the pleura (20% versus 5%); however, none of the patients required tapping. Postoperative bleeding with cardiac tamponade occurred in five patients in the closed pleura group. Six patients in the open pleura group had postoperative bleeding but without tamponade. The average postoperative hospital stay was 7 days for both groups. No significant differences were recorded in postoperative respiratory complications. Conclusions Opening of the pleura during IMA harvesting does not increase the operative morbidity. It may have other advantages and is recommended in most cases of IMA harvesting. PMID:8599790

Scheduling Independent Partitions in Integrated Modular Avionics Systems

PubMed Central

Du, Chenglie; Han, Pengcheng

2016-01-01

Recently the integrated modular avionics (IMA) architecture has been widely adopted by the avionics industry due to its strong partition mechanism. Although the IMA architecture can achieve effective cost reduction and reliability enhancement in the development of avionics systems, it results in a complex allocation and scheduling problem. All partitions in an IMA system should be integrated together according to a proper schedule such that their deadlines will be met even under the worst case situations. In order to help provide a proper scheduling table for all partitions in IMA systems, we study the schedulability of independent partitions on a multiprocessor platform in this paper. We firstly present an exact formulation to calculate the maximum scaling factor and determine whether all partitions are schedulable on a limited number of processors. Then with a Game Theory analogy, we design an approximation algorithm to solve the scheduling problem of partitions, by allowing each partition to optimize its own schedule according to the allocations of the others. Finally, simulation experiments are conducted to show the efficiency and reliability of the approach proposed in terms of time consumption and acceptance ratio. PMID:27942013

Coordination chemistry and insulin-enhancing behavior of vanadium complexes with maltol C6H6O3 structural isomers.

PubMed

Saatchi, Katayoun; Thompson, Katherine H; Patrick, Brian O; Pink, Maren; Yuen, Violet G; McNeill, John H; Orvig, Chris

2005-04-18

Syntheses of vanadium complexes using the naturally occurring ligands isomaltol (Hima) and allomaltol (Hama), as well as a newly synthesized, potentially tetradentate diaminodipyrone [H(2)(en(ama)(2)], are reported. Complete characterization of the resulting compounds [trans-VO(ima)(2)(H(2)O), VO(ama)(2), V(ima)(3), V(ama)(3) and VO(en(ama)(2))], including X-ray crystallography analyses for trans-VO(ima)(2)(H(2)O) and V(ima)(3), are presented herein. Potentiometric titrations (25 degrees C, I = 0.16 M NaCl) were used to measure stability constants in the V(IV)-Hima system; these data were compared to previous data collected on the V(IV)-L (L = Hma, Hama) systems. The in vivo efficacy of these compounds to lower the blood glucose levels of STZ-diabetic rats was tested; all but VO(en(ama)(2)) produced significant decreases in plasma glucose levels. The results were compared to those of the benchmark compound BMOV [VO(ma)(2), bis(maltolato)oxovanadium(IV)], a known insulin-enhancing agent.

C-reactive protein in relation to early atherosclerosis and periodontitis.

PubMed

Yakob, Maha; Meurman, Jukka H; Jogestrand, Tomas; Nowak, Jacek; Söder, Per-Östen; Söder, Birgitta

2012-02-01

Periodontitis may affect atherosclerosis via the chronic inflammation. We investigated high-sensitivity C-reactive protein (hsCRP) in relation to early vascular atherosclerotic changes in non-symptomatic subjects with and without long-term periodontitis. Carotid ultrasonography with calculation of common carotid artery intima-media area (cIMA) was performed, and hsCRP and atherosclerosis risk factors were analysed in randomly chosen 93 patients with periodontitis and 41 controls. The relationship between hsCRP, cIMA and atherosclerosis risk factors was evaluated with multiple logistic regression analysis. Women displayed lower hsCRP (p < 0.05) and higher serum HDL (p < 0.001) than men. In all patients with periodontitis, cIMA values were higher than in controls. Periodontitis appeared to be a major predictor for increased cIMA (odds ratio, 3.82; 95% confidence interval, 1.19-12.26). Neither of these factors was significantly associated with hsCRP which thus appeared not sensitive enough to be a marker for periodontitis or atherosclerosis. Hence, irrespective of low hsCRP levels, periodontitis appeared to increase the risk for atherosclerosis.

Scarf versus chevron osteotomy in hallux valgus: a randomized controlled trial in 96 patients.

PubMed

Deenik, A R; Pilot, P; Brandt, S E; van Mameren, H; Geesink, R G T; Draijer, W F

2007-05-01

The degree of correction of hallux valgus deformity using a distal chevron osteotomy is reported as limited. The scarf osteotomy is reported to correct large intermetatarsal angles (IMA). The purpose of this study was to evaluate if one technique gave greater correction of the IMA and hallux valgus angle (HVA) than the other. After informed consent, 96 feet in 83 patients were randomized into two treatment groups (49 scarf and 47 chevron osteotomies). The results were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) Hallux Valgus Scale and radiographic HVA and IMA measurements. At 27 (range 23-31) months followup both groups improved. The AOFAS score in the chevron group improved from 48 to 89 points and in the scarf group from 47 to 91 points. In the chevron group the HVA corrected from 30 to 17 degrees, and in the scarf group the HVA corrected from 29 to 18 degrees. In both groups, the IMA was corrected from 13 to 10 degrees. The differences were not statistically significant. Three patients in the chevron group developed a partial metatarsal head necrosis. In the scarf group, four patients developed grade 1 complex regional pain syndrome compared to one patient in the chevron group. No differences of statistical significance could be measured between the two groups with respect to the AOFAS score, HVA, and IMA. Although both groups showed good to excellent results, we favor the chevron osteotomy because the procedure is technically less demanding.

Cytokine profile in canine immune-mediated polyarthritis and osteoarthritis.

PubMed

Hegemann, N; Wondimu, A; Kohn, B; Brunnberg, L; Schmidt, M F G

2005-01-01

The purpose of this study was to determine the cytokine profile in 21 dogs with canine immune-mediated polyarthritis (IMA) and 15 dogs with osteoarthritis (OA) caused by cranial cruciate ligament rupture (CCLR). The mRNA expression of interleukin (IL)-1alpha, IL-1beta, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-18, interferon (IFN)-gamma, transforming growth factor (TGF)-beta, and tumour necrosis factor (TNF)-alpha were analysed in synovial fluid by semi-quantitative RT-PCR, while TNF-alpha protein was determined by L929 cytotoxicity assay. The frequency of lymphocytes was analysed using FACScan. Both disorders reveal a similar cytokine expression pattern, except for significant lower IL-1beta expression in OA. Th1 cytokines IL-2 and IFN-gamma were detected, while IL-4 was nearly absent in IMA and OA. Furthermore, the bioassay demonstrates a significantly higher production of TNF-alpha in synovial fluid of dogs with IMA, compared to dogs with OA (p < 0.05). The frequency of CD4+, CD8+ and MHC class II+ cells was relatively higher in synovial fluids compared to peripheral blood in IMA. These findings reveal that the difference between the cytokine pattern of canine IMA and OA seems to be rather quantitative than qualitative. Both joint disorders show predominance of pro-inflammatory cytokines and absence of TH2 cytokine expression, indicating the potential of IL-4 for a gene therapeutic approach.

Vagal Afferent Innervation of the Lower Esophageal Sphincter

PubMed Central

Powley, Terry L.; Baronowsky, Elizabeth A.; Gilbert, Jared M.; Hudson, Cherie N.; Martin, Felecia N.; Mason, Jacqueline K.; McAdams, Jennifer L.; Phillips, Robert J.

2013-01-01

To supply a fuller morphological characterization of the vagal afferents innervating the lower esophageal sphincter (LES), specifically to label vagal terminals in the tissues forming the LES in the gastroesophageal junction, the present experiment employed injections of dextran biotin into the nodose ganglia of rats. Four types of vagal afferents innervated the LES. Clasp and sling muscle fibers were directly and prominently innervated by intramuscular arrays (IMAs). Individual IMA terminals subtended about 16° of arc of the esophageal circumference, and, collectively, the terminal fields were distributed within the muscle ring to establish a 360° annulus of mechanoreceptors in the sphincter wall. 3D morphometry of the terminals established that, compared to sling muscle IMAs, clasp muscle IMAs had more extensive arbors and larger receptive fields. In addition, at the cardia, local myenteric ganglia between smooth muscle sheets and striated muscle bundles were innervated by intraganglionic laminar endings (IGLEs), in a pattern similar to the innervation of the myenteric plexus throughout the stomach and esophagus. Finally, as previously described, the principle bundle of sling muscle fibers that links LES sphincter tissue to the antropyloric region of the lesser curvature was innervated by exceptionally long IMAs as well as by unique web ending specializations at the distal attachment of the bundle. Overall, the specialized varieties of densely distributed vagal afferents innervating the LES underscore the conclusion that these sensory projections are critically involved in generating LES reflexes and may be promising targets for managing esophageal dysfunctions. PMID:23583280

Headquarters Task Group 8.5 Operation Plan 2-1-62 Operation Order 2-1-62, Effective ____1962 for Operation Dominic

DTIC Science & Technology

1962-03-22

1-62 Operation Order 2-1-62, Effective ____1962 for Operation Dominic 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...q TG-8.5, 15 Jan 62 co Camand Program Schedule, Eq JTF-8, 17 Jan 62 d. m, Mractor IMA to Wartagcr AID, f i l e referr82 HA-DA-DBA Qtcd l 8 Dec...Establishing the basic secur i ty program of TG 8.5. (c) Developing and dirreminating secur i ty measure8 for action by !CG 8.5 elements. (d) Providing c

Dysfunction of the Human Mirror Neuron System in Ideomotor Apraxia: Evidence from Mu Suppression.

PubMed

Frenkel-Toledo, Silvi; Liebermann, Dario G; Bentin, Shlomo; Soroker, Nachum

2016-06-01

Stroke patients with ideomotor apraxia (IMA) have difficulties controlling voluntary motor actions, as clearly seen when asked to imitate simple gestures performed by the examiner. Despite extensive research, the neurophysiological mechanisms underlying failure to imitate gestures in IMA remain controversial. The aim of the current study was to explore the relationship between imitation failure in IMA and mirror neuron system (MNS) functioning. Mirror neurons were found to play a crucial role in movement imitation and in imitation-based motor learning. Their recruitment during movement observation and execution is signaled in EEG recordings by suppression of the lower (8-10 Hz) mu range. We examined the modulation of EEG in this range in stroke patients with left (n = 21) and right (n = 15) hemisphere damage during observation of video clips showing different manual movements. IMA severity was assessed by the DeRenzi standardized diagnostic test. Results showed that failure to imitate observed manual movements correlated with diminished mu suppression in patients with damage to the right inferior parietal lobule and in patients with damage to the right inferior frontal gyrus pars opercularis-areas where major components of the human MNS are assumed to reside. Voxel-based lesion symptom mapping revealed a significant impact on imitation capacity for the left inferior and superior parietal lobules and the left post central gyrus. Both left and right hemisphere damages were associated with imitation failure typical of IMA, yet a clear demonstration of relationship to the MNS was obtained only in the right hemisphere damage group. Suppression of the 8-10 Hz range was stronger in central compared with occipital sites, pointing to a dominant implication of mu rather than alpha rhythms. However, the suppression correlated with De Renzi's apraxia test scores not only in central but also in occipital sites, suggesting a multifactorial mechanism for IMA, with a possible impact for deranged visual attention (alpha suppression) beyond the effect of MNS damage (mu suppression).

Reliability of Wearable Inertial Measurement Units to Measure Physical Activity in Team Handball.

PubMed

Luteberget, Live S; Holme, Benjamin R; Spencer, Matt

2018-04-01

To assess the reliability and sensitivity of commercially available inertial measurement units to measure physical activity in team handball. Twenty-two handball players were instrumented with 2 inertial measurement units (OptimEye S5; Catapult Sports, Melbourne, Australia) taped together. They participated in either a laboratory assessment (n = 10) consisting of 7 team handball-specific tasks or field assessment (n = 12) conducted in 12 training sessions. Variables, including PlayerLoad™ and inertial movement analysis (IMA) magnitude and counts, were extracted from the manufacturers' software. IMA counts were divided into intensity bands of low (1.5-2.5 m·s -1 ), medium (2.5-3.5 m·s -1 ), high (>3.5 m·s -1 ), medium/high (>2.5 m·s -1 ), and total (>1.5 m·s -1 ). Reliability between devices and sensitivity was established using coefficient of variation (CV) and smallest worthwhile difference (SWD). Laboratory assessment: IMA magnitude showed a good reliability (CV = 3.1%) in well-controlled tasks. CV increased (4.4-6.7%) in more-complex tasks. Field assessment: Total IMA counts (CV = 1.8% and SWD = 2.5%), PlayerLoad (CV = 0.9% and SWD = 2.1%), and their associated variables (CV = 0.4-1.7%) showed a good reliability, well below the SWD. However, the CV of IMA increased when categorized into intensity bands (2.9-5.6%). The reliability of IMA counts was good when data were displayed as total, high, or medium/high counts. A good reliability for PlayerLoad and associated variables was evident. The CV of the previously mentioned variables was well below the SWD, suggesting that OptimEye's inertial measurement unit and its software are sensitive for use in team handball.

Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family*

PubMed Central

Teste, Marie-Ange; François, Jean Marie; Parrou, Jean-Luc

2010-01-01

It has been known for a long time that the yeast Saccharomyces cerevisiae can assimilate α-methylglucopyranoside and isomaltose. We here report the identification of 5 genes (YGR287c, YIL172c, YJL216c, YJL221c and YOL157c), which, similar to the SUCx, MALx, or HXTx multigene families, are located in the subtelomeric regions of different chromosomes. They share high nucleotide sequence identities between themselves (66–100%) and with the MALx2 genes (63–74%). Comparison of their amino acid sequences underlined a substitution of threonine by valine in region II, one of the four highly conserved regions of the α-glucosidase family. This change was previously shown to be sufficient to discriminate α-1,4- to α-1,6-glucosidase activity in YGR287c (Yamamoto, K., Nakayama, A., Yamamoto, Y., and Tabata, S. (2004) Eur. J. Biochem. 271, 3414–3420). We showed that each of these five genes encodes a protein with α-glucosidase activity on isomaltose, and we therefore renamed these genes IMA1 to IMA5 for IsoMAltase. Our results also illustrated that sequence polymorphisms among this family led to interesting variability of gene expression patterns and of catalytic efficiencies on different substrates, which altogether should account for the absence of functional redundancy for growth on isomaltose. Indeed, deletion studies revealed that IMA1/YGR287c encodes the major isomaltase and that growth on isomaltose required the presence of AGT1, which encodes an α-glucoside transporter. Expressions of IMA1 and IMA5/YJL216c were strongly induced by maltose, isomaltose, and α-methylglucopyranoside, in accordance with their regulation by the Malx3p-transcription system. The physiological relevance of this IMAx multigene family in S. cerevisiae is discussed. PMID:20562106

Effect of Ventilation Support on Oxidative Stress and Ischemia-Modified Albumin in Neonates.

PubMed

Dursun, Arzu; Okumuş, Nurullah; Erol, Sara; Bayrak, Tülin; Zenciroğlu, Ayşegül

2016-01-01

Mechanical ventilation (MV) can induce oxidative stress, which plays a critical role in pulmonary injury in intubated neonates. Ischemia-modified albumin (IMA)-a variant of human serum albumin-is a novel biomarker of myocardial ischemia that occurs due to reactive oxygen species during ischemic insult. This study aimed to investigate IMA production due to oxidative stress induced during MV in neonates. This study included 17 neonates that were ventilated using synchronized intermittent mechanical ventilation (SIMV; SIMV group) and 20 neonates ventilated using continuous positive airway pressure (CPAP; CPAP group). Blood samples were collected from each neonate during ventilation support and following cessation of ventilation support. Total antioxidant capacity (TAC) and total oxidant status (TOS) were measured using the Erel method. IMA was measured via an enzyme-linked immunosorbent assay kit (Cusabio Biotech Co., Ltd., Wuhan, China). The oxidant stress index (OSI) was calculated as OSI = TOS/TAC. Statistical analysis was performed using SPSS v.18.0 (SPSS Inc., Chicago, IL) for Windows. Among the neonates included in the study, mean gestational age was 34.7 ± 3.8 weeks, mean birth weight was 2,553 ± 904 g, and 54% were premature. There were not any significant differences in mean gestational age or birth weight between the SIMV and CPAP groups. Among the neonates in both the groups, mean IMA, TOS, and OSI levels were significantly higher during ventilation support (102.2 ± 9.3 IU mL(-1), 15.5 ± 1.3 µmol H2O2 equivalent L(-1), and 0.85 ± 0.22 arbitrary units [ABU], respectively), as compared with following cessation of ventilation support (82.9 ± 11.9 IU mL(-1), 13.4 ± 1.3 µmol H2O2 equivalent L(-1), and 0.64 ± 0.14 ABU, respectively) (p = 0.001). Among all the neonates in the study, mean TAC was significantly lower during ventilation support than the postventilation support (1.82 ± 0.28 mmol 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid [Trolox] equivalent L(-1) vs. 2.16 ± 0.31 mmol Trolox equivalent L(-1)) (p = 0.001). There were no significant differences in mean TAC, OSI, or IMA levels between the SIMV and CPAP groups. The mean TOS level during ventilation support and the mean difference in TOS between during and postventilation support was significantly greater in the CPAP group than in the SIMV group. There were no significant relationships between the mean TOS, TAC, OSI, or IMA levels, and gestational age of the neonates. SIMV and CPAP activated the oxidative stress and increased the IMA level in neonates; therefore, measurement of IMA and oxidant markers may be useful in the follow-up of lung injury in neonates due to ventilation support. Additional prospective studies are needed to compare the effects of various ventilation methods on oxidative stress and the IMA level in neonates. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Evaluating Virtual Reality and Augmented Reality Training for Industrial Maintenance and Assembly Tasks

ERIC Educational Resources Information Center

Gavish, Nirit; Gutiérrez, Teresa; Webel, Sabine; Rodríguez, Jorge; Peveri, Matteo; Bockholt, Uli; Tecchia, Franco

2015-01-01

The current study evaluated the use of virtual reality (VR) and augmented reality (AR) platforms, developed within the scope of the SKILLS Integrated Project, for industrial maintenance and assembly (IMA) tasks training. VR and AR systems are now widely regarded as promising training platforms for complex and highly demanding IMA tasks. However,…

The internal mammary artery as a shunt in a noncyanotic infant with hemitruncus: surgical and anesthetic management.

PubMed

Mahan, Vicki L; Stevens, Randy M; Mesia, Cesar I; Schwartz, Roy E; Moulick, Achintya N

2016-08-01

The internal mammary artery (IMA) has been used as a systemic-to-pulmonary artery shunt in selected patients with congenital heart disease. Growth and development of hypoplastic pulmonary arteries have been described. We discuss the surgical and anesthetic management of an infant with an atretic-thrombosed right pulmonary artery originating from the ascending aorta in whom the IMA was used to create a systemic-to-pulmonary artery shunt after failure of a previous shunt and later successful pulmonary artery reconstruction. The IMA should be considered as an alternative conduit in patients requiring a systemic-to-pulmonary artery shunt for growth of pulmonary arteries. Copyright © 2016 Elsevier Inc. All rights reserved.

Heartland Engineers: A Century of Superior Service 1907-2007

DTIC Science & Technology

2009-01-01

NJ SUPERFUND SITE, REMEDIAL DESIGN 104. INDEPENDENCE AAF: OEW LMS ASR-NOFA 105. INDEPENDENCE SATELLITE POW CAMP: PA/INPR 106. INVES. & ASSESS IMA-AR...the development of nuclear weaponry, under the Formerly Used Sites Remedial Action Plan (FUSRAP) for the Department of Energy as well as Formerly Used...further assist in the cleanup of Cold War legacy wastes through the U.S. Depart- ment of Energy’s Formerly Utilized Sites Remedial Action Program

Perovskite classification: An Excel spreadsheet to determine and depict end-member proportions for the perovskite- and vapnikite-subgroups of the perovskite supergroup

NASA Astrophysics Data System (ADS)

Locock, Andrew J.; Mitchell, Roger H.

2018-04-01

Perovskite mineral oxides commonly exhibit extensive solid-solution, and are therefore classified on the basis of the proportions of their ideal end-members. A uniform sequence of calculation of the end-members is required if comparisons are to be made between different sets of analytical data. A Microsoft Excel spreadsheet has been programmed to assist with the classification and depiction of the minerals of the perovskite- and vapnikite-subgroups following the 2017 nomenclature of the perovskite supergroup recommended by the International Mineralogical Association (IMA). Compositional data for up to 36 elements are input into the spreadsheet as oxides in weight percent. For each analysis, the output includes the formula, the normalized proportions of 15 end-members, and the percentage of cations which cannot be assigned to those end-members. The data are automatically plotted onto the ternary and quaternary diagrams recommended by the IMA for depiction of perovskite compositions. Up to 200 analyses can be entered into the spreadsheet, which is accompanied by data calculated for 140 perovskite compositions compiled from the literature.

The Ima Hogg Therapeutic School Individualized Education, Behavioral Management in the Classroom and Psychotherapy for the Emotionally Disturbed and Behaviorally Disordered Child.

ERIC Educational Resources Information Center

Wood, Constance D.; And Others

Three papers discuss aspects of The Ima Hogg Therapeutic School for emotionally disturbed children. The first paper addresses the school's behavior development and management system, which rewards self management with freedom in physical activity and uses individualized target behaviors designed to increase the child's acceptable social…

Using Video-Based Instruction to Integrate Ethics into the Curriculum

ERIC Educational Resources Information Center

Sedaghat, Ali M.; Mintz, Steven M.; Wright, George M.

2011-01-01

This paper describes a video case discussion project based on the IMA's Statement of Ethical Professional Practice that was administered in a cost accounting class to assess the extent to which students were able to identify and discuss ethical issues raised by the facts of a case scenario. The case was developed by the IMA to advance the…

Time Triggered Protocol (TTP) for Integrated Modular Avionics

NASA Technical Reports Server (NTRS)

Motzet, Guenter; Gwaltney, David A.; Bauer, Guenther; Jakovljevic, Mirko; Gagea, Leonard

2006-01-01

Traditional avionics computing systems are federated, with each system provided on a number of dedicated hardware units. Federated applications are physically separated from one another and analysis of the systems is undertaken individually. Integrated Modular Avionics (IMA) takes these federated functions and integrates them on a common computing platform in a tightly deterministic distributed real-time network of computing modules in which the different applications can run. IMA supports different levels of criticality in the same computing resource and provides a platform for implementation of fault tolerance through hardware and application redundancy. Modular implementation has distinct benefits in design, testing and system maintainability. This paper covers the requirements for fault tolerant bus systems used to provide reliable communication between IMA computing modules. An overview of the Time Triggered Protocol (TTP) specification and implementation as a reliable solution for IMA systems is presented. Application examples in aircraft avionics and a development system for future space application are covered. The commercially available TTP controller can be also be implemented in an FPGA and the results from implementation studies are covered. Finally future direction for the application of TTP and related development activities are presented.

Role of PDGFs/PDGFRs signaling pathway in myocardial fibrosis of DOCA/salt hypertensive rats

PubMed Central

Fan, Bin; Ma, Likun; Li, Qian; Wang, Lin; Zhou, Junling; Wu, Jiawei

2014-01-01

This study aimed to investigate the role of PDGF/PDGFR signaling pathway in myocardial fibrosis of desoxycorticosterone (DOCA) induced salt-sensitive hypertensive rats and explore the influence of PDGF/PDGFR signaling pathway on fibroblasts and myofibroblasts in the heart. 60 male SD rats underwent right nephrectomy and bred with 1% sodium chloride and 0.1% potassium chloride for 4 weeks, and then randomly divided into 3 groups (CON group, DOCA group and DOCA+IMA group). Results showed that: 1) 14 and 28 days after intervention, the SBP in DOCA and DOCA+IMA group was significantly higher than that in CON group. At days 28, the severity of myocardial fibrosis and PVCA/VA ratio in DOCA group were significantly increased when compared with CON group. The severity of myocardial fibrosis and PVCA/VA ratio in DOCA+IMA group were markedly lower than those in DOCA group although they were higher than those in CON group. 2) At days 14, the mRNA expressions of PDGFRα and PDGFRβ in DOCA group were significantly higher than CON and DOCA+IMA group. At days 28, the mRNA expressions of PDGFRβ, FSP-1, α-SMA, procollagen I and procollagen III in DOCA group were significantly higher than those in CON group. In addition, in a specific group, the PDGFRβ mRNA expression was higher than the PDGFRα mRNA expression. In DOCA+IMA group, the mRNA expressions of PDGFRβ, FSP-1, α-SMA, procollagen I and procollagen III were markedly reduced when compared with DOCA group. 3) At 14 days, the protein expressions of PDGFRα and PDGFRβ in DOCA group were significantly higher than those in CON group. The PDGFRα protein expression in DOCA+IMA group was markedly lower than that in DOCA group. At days 28, the protein expressions of PDGFRα and PDGFRβ in DOCA group were significantly increased when compared with CON group. The protein expressions of PDGFRα and PDGFRβ in DOCA+IMA group were significantly lower than those in DOCA group. At day 28, the cardiac interstitium mainly contained vimentin positive fibroblasts, and α-SMA positive cells were less identified in CON group. In DOCA group, α-SMA positive fibroblasts (spindle-shaped) increased significantly, but the myofibroblasts reduced significantly in DOCA+IMA group when compared with DOCA group. 4) PDGFRα protein expression was observed in fibroblasts and myofibroblasts, but not in VSMCs. PDGFRβ protein expression was noted in not only fibroblasts and myofibroblasts but also VSMCs. Thus, During myocardial fibrosis of DOCA induced salt-sensitive hypertensive rats, PDGFRα acts at early stage, but PDGFRβ functions in the whole process. PDGFRα and PDGFRβ expressions increase in fibroblasts and myofibroblasts, suggesting that PDGF/PDGFR signaling pathway is involved in the myocardial fibrosis via stimulating fibroblasts to proliferate and transform into myofibroblasts. PMID:24427322

Validation materielle d'une architecture generique de reseaux avioniques basee sur une gestion modulaire de la redondance

NASA Astrophysics Data System (ADS)

Tremblay, Jose-Philippe

Les systemes avioniques ne cessent d'evoluer depuis l'apparition des technologies numeriques au tournant des annees 60. Apres le passage par plusieurs paradigmes de developpement, ces systemes suivent maintenant l'approche " Integrated Modular Avionics " (IMA) depuis le debut des annees 2000. Contrairement aux methodes anterieures, cette approche est basee sur une conception modulaire, un partage de ressources generiques entre plusieurs systemes et l'utilisation plus poussee de bus multiplexes. La plupart des concepts utilises par l'architecture IMA, bien que deja connus dans le domaine de l'informatique distribuee, constituent un changement marque par rapport aux modeles anterieurs dans le monde avionique. Ceux-ci viennent s'ajouter aux contraintes importantes de l'avionique classique telles que le determinisme, le temps reel, la certification et les cibles elevees de fiabilite. L'adoption de l'approche IMA a declenche une revision de plusieurs aspects de la conception, de la certification et de l'implementation d'un systeme IMA afin d'en tirer profit. Cette revision, ralentie par les contraintes avioniques, est toujours en cours, et offre encore l'opportunite de developpement de nouveaux outils, methodes et modeles a tous les niveaux du processus d'implementation d?un systeme IMA. Dans un contexte de proposition et de validation d'une nouvelle architecture IMA pour un reseau generique de capteurs a bord d?un avion, nous avons identifie quelques aspects des differentes approches traditionnelles pour la realisation de ce type d?architecture pouvant etre ameliores. Afin de remedier a certaines des differentes lacunes identifiees, nous avons propose une approche de validation basee sur une plateforme materielle reconfigurable ainsi qu'une nouvelle approche de gestion de la redondance pour l'atteinte des cibles de fiabilite. Contrairement aux outils statiques plus limites satisfaisant les besoins pour la conception d'une architecture federee, notre approche de validation est specifiquement developpee de maniere a faciliter la conception d'une architecture IMA. Dans le cadre de cette these, trois axes principaux de contributions originales se sont degages des travaux executes suivant les differents objectifs de recherche enonces precedemment. Le premier axe se situe au niveau de la proposition d'une architecture hierarchique de reseau de capteurs s'appuyant sur le modele de base de la norme IEEE 1451. Cette norme facilite l'integration de capteurs et actuateurs intelligents a tout systeme de commande par des interfaces normalisees et generiques.

A synergistic role of ischemia modified albumin and high-sensitivity troponin T in the early diagnosis of acute coronary syndrome

PubMed Central

Mehta, Mihir D.; Marwah, Simbita A.; Ghosh, S.; Shah, Hitesh N.; Trivedi, Amit P.; Haridas, N.

2015-01-01

Aim: The aim was to evaluate the role of high sensitivity troponin T and ischemia modified albumin (IMA) and in the early diagnosis of acute coronary syndrome (ACS). Materials and Methods: This was a cross-sectional study that comprised of 120 individuals of which 75 were cases and 45 healthy controls. On the basis of clinical history and 12-lead electrocardiogram, initial diagnosis of ACS was made in the cases. High sensitive cardiac troponin T (hs-cTnT) and IMA were measured in all the individuals. Results: Levels of IMA were significantly higher in patients of ACS as compared to those in control group (means: 101.83 [95% confidence interval (CI): 91.96–111.70] vs. 41.11 [95% CI: 38.55–43.67]). By taking the cut-off as >65.23 U/mL for IMA, which was obtained from receiver operating characteristic (ROC) curve, the sensitivity was 91.3%, specificity was 81.1%, positive predictive value (PPV) was 74.4%, and negative predictive value (NPV) was 93.9%. Positive likelihood ratio was 4.83 while negative likelihood ratio was 0.11, whereas the corresponding values in case of hs-cTnT were 95.6% (95% CI: 85.2–99.5), 61.3% (95% CI: 49.5–72.6), 59.7%, 95.8%, 2.47 and 0.07 by taking cut-off as >14 pg/mL. The area under the ROC curves (AUC) of IMA and hs-cTnT at 0–6 h were 0.932 (95% CI: 0.87–0.97, P < 0.001) and 0.797 (95% CI: 0.71–0.86, P < 0.001), respectively. The logistic model combining the two markers yielded sensitivity, specificity, PPV, and NPV of 95.7%, 81.1%, 88.6%, and 92.5% respectively. Conclusion: hs-cTnT and IMA may be useful tools for risk stratification of ACS and can be used together with better accuracy in the early diagnosis of ACS. PMID:26985418

Descriptive quantitative analysis of hallux abductovalgus transverse plane radiographic parameters.

PubMed

Meyr, Andrew J; Myers, Adam; Pontious, Jane

2014-01-01

Although the transverse plane radiographic parameters of the first intermetatarsal angle (IMA), hallux abductus angle (HAA), and the metatarsal-sesamoid position (MSP) form the basis of preoperative procedure selection and postoperative surgical evaluation of the hallux abductovalgus deformity, the so-called normal values of these measurements have not been well established. The objectives of the present study were to (1) evaluate the descriptive statistics of the first IMA, HAA, and MSP from a large patient population and (2) to determine an objective basis for defining "normal" versus "abnormal" measurements. Anteroposterior foot radiographs from 373 consecutive patients without a history of previous foot and ankle surgery and/or trauma were evaluated for the measurements of the first IMA, HAA, and MSP. The results revealed a mean measurement of 9.93°, 17.59°, and position 3.63 for the first IMA, HAA, and MSP, respectively. An advanced descriptive analysis demonstrated data characteristics of both parametric and nonparametric distributions. Furthermore, clear differentiations in deformity progression were appreciated when the variables were graphically depicted against each other. This could represent a quantitative basis for defining "normal" versus "abnormal" values. From the results of the present study, we have concluded that these radiographic parameters can be more conservatively reported and analyzed using nonparametric descriptive and comparative statistics within medical studies and that the combination of a first IMA, HAA, and MSP at or greater than approximately 10°, 18°, and position 4, respectively, appears to be an objective "tipping point" in terms of deformity progression and might represent an upper limit of acceptable in terms of surgical deformity correction. Copyright © 2014 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

The anterior visceral branches of the abdominal aorta and their relationship to the renal arteries.

PubMed

Pennington, Neil; Soames, Roger W

2005-12-01

Variations in the anatomy of the abdominal aorta and its branches are of interest as vessel geometry not only determines flow dynamics, but is also crucial in the pathogenesis of vascular disease. The relationship between the anterior visceral and renal arteries is important when undertaking diagnostic arteriography and endovascular interventions. To examine these relationships, the length of the abdominal aorta was determined and measurements taken of the position of origin of the celiac artery, superior mesenteric artery (SMA), inferior mesenteric artery (IMA) and renal arteries, as well as the three-dimensional projection of each vessel from the aorta. The mean level of bifurcation of the aorta was at the lower third of the body of L4, with the celiac artery, SMA, renal arteries and IMA arising at the level of the T12/L1 intervertebral disc, upper third of the body of L1, lower third of the body of L1 and lower third of the body of L3, respectively. The horizontal projection of the celiac artery, SMA and IMA was to the left of the midline; in the sagittal plane, the celiac artery and SMA projected anteriorly and the IMA posteriorly; in the coronal plane all vessels projected inferiorly, with the SMA to the right and the IMA to the left. The celiac artery, SMA and both renal arteries all arise from the proximal half of the abdominal aorta within 45 mm of each other, with the origins of the renal arteries being remarkably consistent. It is concluded that the celiac artery and SMA are both useful landmarks for determining the position of the renal arteries.

Development of intramammary delivery systems containing lasalocid for the treatment of bovine mastitis: impact of solubility improvement on safety, efficacy, and milk distribution in dairy cattle

PubMed Central

Wang, Wen; Song, Yunmei; Petrovski, Kiro; Eats, Patricia; Trott, Darren J; Wong, Hui San; Page, Stephen W; Perry, Jeanette; Garg, Sanjay

2015-01-01

Background Mastitis is a major disease of dairy cattle. Given the recent emergence of methicillin-resistant Staphylococcus aureus as a cause of bovine mastitis, new intramammary (IMA) treatments are urgently required. Lasalocid, a member of the polyether ionophore class of antimicrobial agents, has not been previously administered to cows by the IMA route and has favorable characteristics for development as a mastitis treatment. This study aimed to develop an IMA drug delivery system (IMDS) of lasalocid for the treatment of bovine mastitis. Methods Minimum inhibitory concentrations (MICs) were determined applying the procedures recommended by the Clinical and Laboratory Standards Institute. Solid dispersions (SDs) of lasalocid were prepared and characterized using differential scanning calorimetry and Fourier transform infrared spectroscopy. IMDSs containing lasalocid of micronized, nano-sized, or as SD form were tested for their IMA safety in cows. Therapeutic efficacy of lasalocid IMDSs was tested in a bovine model involving experimental IMA challenge with the mastitis pathogen Streptococcus uberis. Results Lasalocid demonstrated antimicrobial activity against the major Gram-positive mastitis pathogens including S. aureus (MIC range 0.5–8 μg/mL). The solubility test confirmed limited, ion-strength-dependent water solubility of lasalocid. A kinetic solubility study showed that SDs effectively enhanced water solubility of lasalocid (21–35-fold). Polyvinylpyrrolidone (PVP)-lasalocid SD caused minimum mammary irritation in treated cows and exhibited faster distribution in milk than either nano or microsized lasalocid. IMDSs with PVP-lasalocid SD provided effective treatment with a higher mastitis clinical and microbiological cure rate (66.7%) compared to cloxacillin (62.5%). Conclusion Lasalocid SD IMDS provided high cure rates and effectiveness in treating bovine mastitis with acceptable safety in treated cows. PMID:25653501

Development of intramammary delivery systems containing lasalocid for the treatment of bovine mastitis: impact of solubility improvement on safety, efficacy, and milk distribution in dairy cattle.

PubMed

Wang, Wen; Song, Yunmei; Petrovski, Kiro; Eats, Patricia; Trott, Darren J; Wong, Hui San; Page, Stephen W; Perry, Jeanette; Garg, Sanjay

2015-01-01

Mastitis is a major disease of dairy cattle. Given the recent emergence of methicillin-resistant Staphylococcus aureus as a cause of bovine mastitis, new intramammary (IMA) treatments are urgently required. Lasalocid, a member of the polyether ionophore class of antimicrobial agents, has not been previously administered to cows by the IMA route and has favorable characteristics for development as a mastitis treatment. This study aimed to develop an IMA drug delivery system (IMDS) of lasalocid for the treatment of bovine mastitis. Minimum inhibitory concentrations (MICs) were determined applying the procedures recommended by the Clinical and Laboratory Standards Institute. Solid dispersions (SDs) of lasalocid were prepared and characterized using differential scanning calorimetry and Fourier transform infrared spectroscopy. IMDSs containing lasalocid of micronized, nano-sized, or as SD form were tested for their IMA safety in cows. Therapeutic efficacy of lasalocid IMDSs was tested in a bovine model involving experimental IMA challenge with the mastitis pathogen Streptococcus uberis. Lasalocid demonstrated antimicrobial activity against the major Gram-positive mastitis pathogens including S. aureus (MIC range 0.5-8 μg/mL). The solubility test confirmed limited, ion-strength-dependent water solubility of lasalocid. A kinetic solubility study showed that SDs effectively enhanced water solubility of lasalocid (21-35-fold). Polyvinylpyrrolidone (PVP)-lasalocid SD caused minimum mammary irritation in treated cows and exhibited faster distribution in milk than either nano or microsized lasalocid. IMDSs with PVP-lasalocid SD provided effective treatment with a higher mastitis clinical and microbiological cure rate (66.7%) compared to cloxacillin (62.5%). Lasalocid SD IMDS provided high cure rates and effectiveness in treating bovine mastitis with acceptable safety in treated cows.

Serum ischemia modified albumin level and its relationship with the thiol/disulfide balance in placenta percreta patients.

PubMed

Uyanikoglu, Hacer; Sak, Muhammet Erdal; Tatli, Faik; Hilali, Nese Gul; Sak, Sibel; Incebiyik, Adnan; Barut, Mert Ulas; Erel, Ozcan; Gonel, Ataman

2018-06-08

The pathogenesis of placenta percreta (PP) is not very well known. This study was designed to analyse the oxidative stress (OS), the thiol/disulphide balance, and ischaemia-modified albumin (IMA) the women with PP. The study included 38 pregnant women with PP and 40 similarly aged healthy pregnant women in their third trimester of gestation. We measured the IMA, native and total thiols, and disulphide concentrations in the maternal sera of all of the participating women. The IMA levels were higher and the native and total thiols were lower in the PP group than in the control group. However, there was no statistical significance with respect to the thiol/disulphide balance between the two groups. The results of this study suggest that an increase in the ischaemia and OS and a decrease in the antioxidant status may contribute to the pathogenesis of PP. Impact statement What is already known on this subject? Placenta percreta (PP) is a serious complication of pregnancy. Although there are several studies investigating the pathophysiological mechanism of PP, whether the pathology results from a lack of decidua or from the over-invasiveness of trophoblasts remains controversial. The pathology of PP is poorly understood. What do the results of this study add? This prospective study has shown an increased ischaemia modified albumin (IMA) and a decreased antioxidant capacity in the patients with placenta percreta. The results from 38 women with PP suggest that the serum concentrations of IMA and the oxidative stress parameters may be able to predict PP in cases of uncertainty. What are the implications of these findings for clinical practice and/or further research? The implication of these findings shed light on understanding the pathogenesis of PP for further research.

Albumin as marker for susceptibility to metal ions in metal-on-metal hip prosthesis patients.

PubMed

Facchin, F; Catalani, S; Bianconi, E; Pasquale, D De; Stea, S; Toni, A; Canaider, S; Beraudi, A

2017-04-01

Metal-on-metal (MoM) hip prostheses are known to release chromium and cobalt (Co), which negatively affect the health status, leading to prosthesis explant. Albumin (ALB) is the main serum protein-binding divalent transition metals. Its binding capacity can be affected by gene mutations or modification of the protein N-terminal region, giving the ischaemia-modified albumin (IMA). This study evaluated ALB, at gene and protein level, as marker of individual susceptibility to Co in MoM patients, to understand whether it could be responsible for the different management of this ion. Co was measured in whole blood, serum and urine of 40 MoM patients. A mutational screening of ALB was performed to detect links between mutations and metal binding. Finally, serum concentration of total ALB and IMA were measured. Serum total ALB concentration was in the normal range for all patients. None of the subjects presented mutations in the investigated gene. Whole blood, serum and urine Co did not correlate with serum total ALB or IMA, although IMA was above the normal limit in most subjects. The individual susceptibility is very important for patients' health status. Despite the limited results of this study, we provide indications on possible future investigations on the toxicological response to Co.

Air sampling methods to evaluate microbial contamination in operating theatres: results of a comparative study in an orthopaedics department.

PubMed

Napoli, C; Tafuri, S; Montenegro, L; Cassano, M; Notarnicola, A; Lattarulo, S; Montagna, M T; Moretti, B

2012-02-01

To evaluate the level of microbial contamination of air in operating theatres using active [i.e. surface air system (SAS)] and passive [i.e. index of microbial air contamination (IMA) and nitrocellulose membranes positioned near the wound] sampling systems. Sampling was performed between January 2010 and January 2011 in the operating theatre of the orthopaedics department in a university hospital in Southern Italy. During surgery, the mean bacterial loads recorded were 2232.9 colony-forming units (cfu)/m(2)/h with the IMA method, 123.2 cfu/m(3) with the SAS method and 2768.2 cfu/m(2)/h with the nitrocellulose membranes. Correlation was found between the results of the three methods. Staphylococcus aureus was detected in 12 of 60 operations (20%) with the membranes, five (8.3%) operations with the SAS method, and three operations (5%) with the IMA method. Use of nitrocellulose membranes placed near a wound is a valid method for measuring the microbial contamination of air. This method was more sensitive than the IMA method and was not subject to any calibration bias, unlike active air monitoring systems. Copyright © 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Facility Energy Decision System (FEDS) Assessment Report for Fort Buchanan, Puerto Rico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chvala, William D.; Solana, Amy E.; Dixon, Douglas R.

2005-02-01

This report documents the findings of the Facility Energy Decision System (FEDS) assessment at Fort Buchanan, Puerto Rico, by a team of PNNL engineers under contract to the Installation Management Agency (IMA) Southeast Region Office (SERO). Funding support was also provided by the Department of Energy's Federal Energy Management Program. The purpose of the assessment was to determine how energy is consumed at Fort Buchanan, identify the most cost-effective energy retrofit measures, and calculate the potential energy and cost savings.

Assessment of DoD Wounded Warrior Matters: Selection and Training of Warrior Transition Unit and Wounded Warrior Battalion Leaders and Cadre

DTIC Science & Technology

2014-08-22

balancing cost, schedule, performance, and risk. Observation 1 DODIG-2014-100 │ 9 Warrior Transition Unit Cadre Training Program Facts Over the past 5...understaffed. The DC M&RA, and WWR must continually account for turnover, unplanned losses, and the cyclical nature of Reserve IMA manpower to balance ...provide boards with an update of military and civilian skills and qualifications which may not be included in a members Official Military Personnel

Study of Frequency Transfer via Optical Fiber in the Microwave Domain

DTIC Science & Technology

2009-11-01

DOMAIN M. Amemiya, M. Imae, Y. Fujii, T. Suzuyama, K. Watabe, T. Ikegami , and H. Tsuchida* National Metrology Institute of Japan (NMIJ...Yanagimachi, A. Takamizawa, K. Watabe, T. Ikegami , M. Imae, Y. Fujii, M. Amemiya, K. Nakagawa, K. Ueda, and H. Katori, 2009, “Measuring the frequency of a...Shimazaki, T. Ikegami and S. Ohshima, 2006, “Short term frequency stability tests of two cryogenic sapphire oscillators,” Japanese Journal of

Invasive mucinous adenocarcinoma with lepidic-predominant pattern coexisted with tuberculosis: a case report.

PubMed

Xu, Xinxin; Guo, Yinshi; Li, Qiuying; Yang, Ling; Kang, Jianqiang

2018-06-01

We observed a rare case of invasive mucinous adenocarcinoma (IMA) with a lepidic-predominant pattern accompanied by pulmonary tuberculosis. An 85-year-old man with repeated cough and sputum was admitted to Xinhua Hospital. T-SPOT test result was 212 pg/ml (reference value of negative is < 14 pg/ml), Mycobacterium tuberculosis culture was positive, and tuberculin skin test (PPD) was negative (skin induration < 5 mm). The patient was treated with several courses of antibiotics and anti-tuberculosis treatments. Repeated chest CT scans showed disease progression. Bronchoscopy yielded negative results. PET-CT scans showed negative results. A percutaneous lung biopsy revealed mucin-secreting cells lining the alveolar walls. IMA with a lepidic-predominant pattern was diagnosed after invasiveness was found after experimental treatments. Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present case of IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported yet.

Tuberculosis--a notifiable disease.

PubMed

Roy, Sukhendu; Rai, D R; Suresh, Gutta

2012-10-01

In a landmark development, the Ministry of Health and Family Welfare, Government of India, has taken important steps to establish the compulsory notification of tuberculosis in the country. A Government Order to this effect was issued on 7 May 2012. In addition to this IMA passed a resolution on TB notification in CWC on 22nd April 2012 at Mumbai: "In conformity with the requirements of ISTC, Indian Medical Association (IMA) desires that Notification of TB patient to the National Programme be made mandatory. IMA also recommends to the medical practitioner to follow the ISTC guidelines in diagnosis and management of TB care". Notification of TB will facilitate early diagnosis and treatment, prevention of MDR and XDR, reduce TB deaths, better quality diagnostic and treatment services for the TB patients. RNTCP will realistically estimateTB burden, plan resources and control measures to commensurate with the actual burden of disease.

20 CFR 632.255 - Program planning.

Code of Federal Regulations, 2011 CFR

2011-04-01

... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.255 Program planning. (a)(1) In developing the summer program, the Native American grantee shall coordinate the summer plan..., except that 45 days prior to the beginning of the summer program and 45 days after the summer program...

20 CFR 632.255 - Program planning.

Code of Federal Regulations, 2012 CFR

2012-04-01

... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.255 Program planning. (a)(1) In developing the summer program, the Native American grantee shall coordinate the summer plan..., except that 45 days prior to the beginning of the summer program and 45 days after the summer program...

The effect of L-thyroxine replacement therapy on ischemia-modified albümin and malondialdehyde levels in patients with overt and subclinical hypothyroidism.

PubMed

Erem, Cihangir; Suleyman, Akile Karacin; Civan, Nadim; Mentese, Ahmet; Nuhoglu, İrfan; Uzun, Aysegul; Coskun, Hulya; Deger, Orhan

2016-11-01

The main objective of this study was to evaluate the levels of ischemia-modified albumin (IMA) and malondialdehyde (MDA) in patients with subclinical (SHypo) and overt hypothyroidism (OHypo), and to assess the effects of levothyroxine (LT 4 ) therapy on the oxidative stress (OS) parameters. We also investigated the relationships among serum thyroid hormones, lipid parameters, and IMA and MDA in these patients. Thirty untreated patients with OHypo, 25 untreated patients with Shypo, and 30 age- and sex-matched healthy controls were prospectively included in the study. Biochemical and hormonal parameters including IMA and MDA were evaluated in all patients just before and one month after the maintenance of euthyroidism. Compared with the control subjects, the levels of MDA and triglycerides (TG) significantly increased in patients with SHypo (p < 0.001 and p < 0.05, respectively), whereas high density lipoprotein cholesterol (HDL-C) levels significantly decreased (p = 0.01). Patients with OHypo showed significantly high MDA, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and TG levels (p = 0.001, p < 0.01, p = 0.01, and p < 0.01, respectively), and significantly low HDL-C levels compared with the controls (p < 0.05). MDA levels and lipid profile were not significantly different in the patients with OHypo when compared with the patients with SHypo. Serum IMA levels did not significantly change in patients with OHypo and SHypo compared with the controls. In the pre-treatment period, MDA levels were inversely correlated with HDL-C levels in patients with OHypo (r: -0.471, p = 0.009). Plasma MDA and LDL-C levels significantly decreased and HDL-C levels significantly increased in the groups of OHypo and SHypo after LT 4 treatment. Serum IMA levels did not significantly change with the therapy in all patient groups. Increased MDA levels in both patient groups represent increased lipid peroxidation which might play an important role in the pathogenesis of the atherosclerosis seen in these patients. Increased OS in patients with SHypo and OHypo could be improved by LT 4 treatment. Also, MDA can be used as a reliable marker of OS and oxidative damage, while IMA is considered to be inappropriate.

Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahiout, Selma, E-mail: selma.mahiout@helsinki.fi

The aryl hydrocarbon receptor (AHR) mediates the toxicity of dioxins, but also plays important physiological roles. Selective AHR modulators, which elicit some effects imparted by this receptor without causing the marked toxicity of dioxins, are presently under intense scrutiny. Two novel such compounds are IMA-08401 (N-acetyl-N-phenyl-4-acetoxy-5-chloro-1, 2-dihydro-1-methyl-2-oxo-quinoline-3-carboxamide) and IMA-07101 (N-acetyl-N-(4-trifluoromethylphenyl)-4-acetoxy-1, 2-dihydro-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxamide). They represent, as diacetyl prodrugs, AHR-active metabolites of the drug compounds laquinimod and tasquinimod, respectively, which are intended for the treatment of autoimmune diseases and cancer. Here, we toxicologically assessed the novel compounds in Sprague-Dawley rats, after a single dose (8.75–92.5 mg/kg) and 5-day repeated dosing at the highestmore » doses achievable (IMA-08401: 100 mg/kg/day; and IMA-07101: 75 mg/kg/day). There were no overt clinical signs of toxicity, but body weight gain was marginally retarded, and the treatments induced minimal hepatic extramedullary haematopoiesis. Further, both the absolute and relative weights of the thymus were significantly decreased. Cyp1a1 gene expression was substantially increased in all tissues examined. The hepatic induction profile of other AHR battery genes was distinct from that caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The only marked alterations in serum clinical chemistry variables were a reduction in triglycerides and an increase in 3-hydroxybutyrate. Liver and kidney retinol and retinyl palmitate concentrations were affected largely in the same manner as reported for TCDD. In vitro, the novel compounds activated CYP1A1 effectively in H4IIE cells. Altogether, these novel compounds appear to act as potent activators of the AHR, but lack some major characteristic toxicities of dioxins. They therefore represent promising new selective AHR modulators. - Highlights: • IMA-08401 and IMA-07101 are novel, effective activators of the AHR. • In rats, they lacked the wasting syndrome and thyroid imbalance typical of TCDD. • They also affected the AHR-battery genes in a distinct manner. • Therefore, the compounds appear to represent promising new selective AHR modulators. • They may have potential as drug compound candidates and research tools.« less

Methode de conception dirigee par les modeles pour les systemes avioniques modulaires integres basee sur une approche de cosimulation

NASA Astrophysics Data System (ADS)

Bao, Lin

In the aerospace industry, with the development of avionic systems becomes more and more complex, the integrated modular avionics (IMA) architecture was proposed to replace its predecessor - the federated architecture, in order to reduce the weight, power consumption and the dimension of the avionics equipment. The research work presented in this thesis, which is considered as a part of the research project AVIO509, aims to propose to the aviation industry a set of time-effective and cost-effective solutions for the development and the functional validation of IMA systems. The proposed methodologies mainly focus on two design flows that are based on: 1) the concept of model-driven engineering design and 2) a cosimulation platform. In the first design flow, the modeling language AADL is used to describe the IMA architecture. The environment OCARINA, a code generator initially designed for POK, was modified so that it can generate avionic applications from an AADL model for the simulator SIMA (an IMA simulator compliant to the ARINC653 standards). In the second design flow, Simulink is used to simulate the external world of IMA module thanks to the availability of avionic library that can offer lots of avionics sensors and actuators, and as well as its effectiveness in creating the Simulink models. The cosimulation platform is composed of two simulators: Simulink for the simulation of peripherals and SIMA for the simulation of IMA module, the latter is considered as an ideal alternative for the super expensive commercial development environment. In order to have a good portability, a SIMA partition is reserved as the role of " adapter " to synchronize the communication between these two simulators via the TCP/IP protocol. When the avionics applications are ported to the implementation platform (such as PikeOS) after the simulation, there is only the " adapter " to be modified because the internal communication and the system configuration are the same. An avionics application was developed as a case study, in order to demonstrate the validation of the proposed design flows. The research presented in this paper is a continuation of project of the AVIO509 research team, and parallelly may be extended in the future work.

The change of plasma galectin-3 concentrations after traumatic brain injury.

PubMed

Shen, Yong-Feng; Yu, Wen-Hua; Dong, Xiao-Qiao; Du, Quan; Yang, Ding-Bo; Wu, Gang-Qun; Zhang, Zu-Yong; Wang, Hao; Jiang, Li

2016-05-01

Galectin-3 plays a significant role in microglia activation. Its increased circulating concentration has been associated with some inflammatory diseases. In-hospital major adverse events (IMAEs), including acute traumatic coagulopathy, progressive hemorrhagic injury and posttraumatic cerebral infarction, have high prevalence and are strong predictors of mortality after severe traumatic brain injury (STBI). The present study was designed to investigate the relationships between plasma galectin-3 concentrations and trauma severity, in-hospital mortality and IMAEs following STBI. Plasma galectin-3 concentrations of 100 STBI patients and 100 controls were determined. Diagnosis of progressive hemorrhagic injury and posttraumatic cerebral infarction was made on the follow-up computerized tomography scan. Acute traumatic coagulopathy was defined based on coagulation test. Plasma galectin-3 concentrations were significantly higher in patients as compared to controls and also associated highly with Glasgow Coma Scale scores and plasma C-reactive protein concentrations. Galectin-3 emerged as an independent predictor for in-hospital mortality and IMAEs. Areas under receiver operating characteristic curve of plasma galectin-3 concentrations were similar to those of Glasgow Coma Scale scores for prediction of in-hospital morality and IMAEs. Plasma galectin-3 concentrations have close relation to inflammation, trauma severity and clinical outcome, suggesting that galectin-3 should have the potential to be a good prognostic biomarker after STBI. Copyright © 2016 Elsevier B.V. All rights reserved.

Genito-Urinary Function and Quality of Life after Elective Totally Laparoscopic Sigmoidectomy after at Least One Episode of Complicated Diverticular Disease According to Two Different Vascular Approaches: the IMA Low Ligation or the IMA Preservation.

PubMed

Mari, Giulio; Crippa, Jacopo; Costanzi, Andrea; Mazzola, Michele; Magistro, Carmelo; Ferrari, Giovanni; Maggioni, Dario

2017-01-01

The arterial ligation during elective laparoscopic sigmoidectomy for diverticular disease can affect genito-urinary function injuring the superior hypogastric plexus, and can weaken the distal colonic stump arterial perfusion. Ligation of the inferior mesenteric artery distal to the left colic artery or the complete preservation of the inferior mesenteric artery can therefore be compared in terms of preservation of the descending sympathetic fibres running along the aorta to the rectum resulting in a different post operative genito urinary function. From January 2015 to March 2016, 66 patients underwent elective laparoscopic sigmoidectomy for diverticular disease among two enrolling hospitals. In one centre 35 patients underwent laparoscopic sigmoidectomy with the ligation of the inferior mesenteric artery distal to the left colic artery (low ligation). In the other centre 31 patient were operated on the same procedure with complete inferior mesenteric artery preservation (IMA preservation). There was no difference in terms of major complication occurred, first passage of stool and length of hospital stay between the two groups. Time of surgery was significantly shorter in LL group compared to IMA preserving group and intra operative blood loss was significantly lower in the LL group. There were no differences in the genito urinary function between the two group pre operatively, at 1 and 9 months post operatively. Genito urinary function did not significantly change across surgery in each groups. The low ligation and the IMA preserving vascular approach are safe end feasible techniques in elective laparoscopic sigmoidectomy for diverticular disease. They both prevent from genito-urinary post-operative disfunction and allow good post operative quality of life. The low ligation approach is related to shorter operative time and slower intra operative blood loss. Celsius.

20 CFR 632.262 - Termination date for the summer program.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Termination date for the summer program. 632... INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.262 Termination date for the summer program. Participants may not be enrolled in the summer...

20 CFR 632.262 - Termination date for the summer program.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Termination date for the summer program. 632... INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.262 Termination date for the summer program. Participants may not be enrolled in the summer...

20 CFR 632.262 - Termination date for the summer program.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Termination date for the summer program. 632... INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.262 Termination date for the summer program. Participants may not be enrolled in the summer...

Emergency Immigration Education Act Programs. Summer ESL Welcome Program for Students of Limited English Proficiency, Summer Bilingual Program, Projects Omega, Wise, and Bell. Summer 1994. OER Report.

ERIC Educational Resources Information Center

Roman, Elliott M.

The Emergency Immigration Education Act supported three distinct programs in New York City in the summer of 1994: (1) the Summer English as a Second Language (ESL) Welcome Program for Students of Limited English Proficiency; (2) the Summer Bilingual Program; and (3) Projects Omega, Wise, and Bell. The projects served 3,443 students in all. The…

5 CFR 792.216 - Are Federal employees with children who are enrolled in summer programs and part-time programs...

Code of Federal Regulations, 2012 CFR

2012-01-01

... are enrolled in summer programs and part-time programs eligible for the child care subsidy program... summer programs and part-time programs eligible for the child care subsidy program? Federal employees... enrolled in daytime summer programs and part-time programs such as before and after school programs are...

5 CFR 792.216 - Are Federal employees with children who are enrolled in summer programs and part-time programs...

Code of Federal Regulations, 2011 CFR

2011-01-01

... are enrolled in summer programs and part-time programs eligible for the child care subsidy program... summer programs and part-time programs eligible for the child care subsidy program? Federal employees... enrolled in daytime summer programs and part-time programs such as before and after school programs are...

5 CFR 792.216 - Are Federal employees with children who are enrolled in summer programs and part-time programs...

Code of Federal Regulations, 2010 CFR

2010-01-01

... are enrolled in summer programs and part-time programs eligible for the child care subsidy program... summer programs and part-time programs eligible for the child care subsidy program? Federal employees... enrolled in daytime summer programs and part-time programs such as before and after school programs are...

Summer Training and Education Program (STEP). What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2009

2009-01-01

Summer Training and Education Program (STEP) is a summer employment, academic remediation, and life skills program intended to lower school dropout rates by reducing summer learning loss and preventing teen parenthood. The program is integrated into the federal summer jobs program and is offered during six-to-eight-week sessions in two…

Interfacial oxygen migration and its effect on the magnetic anisotropy in Pt/Co/MgO/Pt films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Xi; Feng, Chun, E-mail: fengchun@ustb.edu.cn, E-mail: ghyu@mater.ustb.edu.cn; Liu, Yang

2014-02-03

This paper reports the interfacial oxygen migration effect and its induced magnetic anisotropy evolution in Pt/Co/MgO/Pt films. During depositing the MgO layer, oxygen atoms from the MgO combine with the neighboring Co atoms, leading to the formation of CoO at the Co/MgO interface. Meanwhile, the films show in-plane magnetic anisotropy (IMA). After annealing, most of the oxygen atoms in CoO migrate back to the MgO layer, resulting in obvious improvement of Co/MgO interface and the enhancement of effective Co-O orbital hybridization. These favor the evolution of magnetic anisotropy from IMA to perpendicular magnetic anisotropy (PMA). The oxygen migration effect ismore » achieved by the redox reaction at the Co/MgO interface. On the contrary, the transfer from IMA to PMA cannot be observed in Pt/Co/Pt films due to the lack of interfacial oxygen migration.« less

Equivalent correction in scarf and chevron osteotomy in moderate and severe hallux valgus: a randomized controlled trial.

PubMed

Deenik, Axel; van Mameren, Henk; de Visser, Enrico; de Waal Malefijt, Maarten; Draijer, Frits; de Bie, Rob

2008-12-01

Chevron osteotomy is a widely accepted osteotomy for correction of hallux valgus.(18) Algorithms were developed to overcome the limitations of distal osteotomies. Scarf osteotomy has become popular as a versatile procedure that should be able to correct most cases of acquired hallux valgus. The purpose of this study was to evaluate whether patients with moderate or severe hallux valgus have better correction with a scarf osteotomy as compared to chevron osteotomy. After informed consent, 136 feet in 115 patients were randomized to 66 scarf and 70 chevron osteotomies. Deformities of patients were classified as mild, moderate and severe according to IMA, and both groups were compared with independent t-tests. The results were measured using radiographic HVA, IMA and DMAA measurements. There were no statistical differences in HVA, IMA and DMAA between scarf and chevron osteotomy in mild to moderate hallux valgus. In severe hallux valgus, chevron osteotomy corrected HVA better than scarf osteotomy, although this group consisted of twelve patients only. Five patients in the chevron group and seven in the scarf group developed recurrent subluxation of the metatarsophalangeal joint. In patients with moderate and severe hallux valgus, the results of chevron osteotomy were at least as effective as a scarf osteotomy. Recurrent subluxation of the first metatatarsophalangeal joint was the main cause for insufficient correction. We favor the chevron osteotomy because it is less invasive, without sacrificing correction of HVA and IMA.

At-MINI ZINC FINGER2 and Sl-INHIBITOR OF MERISTEM ACTIVITY, a Conserved Missing Link in the Regulation of Floral Meristem Termination in Arabidopsis and Tomato.

PubMed

Bollier, Norbert; Sicard, Adrien; Leblond, Julie; Latrasse, David; Gonzalez, Nathalie; Gévaudant, Frédéric; Benhamed, Moussa; Raynaud, Cécile; Lenhard, Michael; Chevalier, Christian; Hernould, Michel; Delmas, Frédéric

2018-01-01

In angiosperms, the gynoecium is the last structure to develop within the flower due to the determinate fate of floral meristem (FM) stem cells. The maintenance of stem cell activity before its arrest at the stage called FM termination affects the number of carpels that develop. The necessary inhibition at this stage of WUSCHEL ( WUS ), which is responsible for stem cell maintenance, involves a two-step mechanism. Direct repression mediated by the MADS domain transcription factor AGAMOUS (AG), followed by indirect repression requiring the C2H2 zinc-finger protein KNUCKLES (KNU), allow for the complete termination of floral stem cell activity. Here, we show that Arabidopsis thaliana MINI ZINC FINGER2 (AtMIF2) and its homolog in tomato ( Solanum lycopersicum ), INHIBITOR OF MERISTEM ACTIVITY (SlIMA), participate in the FM termination process by functioning as adaptor proteins. AtMIF2 and SlIMA recruit AtKNU and SlKNU, respectively, to form a transcriptional repressor complex together with TOPLESS and HISTONE DEACETYLASE19. AtMIF2 and SlIMA bind to the WUS and SlWUS loci in the respective plants, leading to their repression. These results provide important insights into the molecular mechanisms governing (FM) termination and highlight the essential role of AtMIF2/SlIMA during this developmental step, which determines carpel number and therefore fruit size. © 2018 American Society of Plant Biologists. All rights reserved.

7 CFR 250.62 - Summer Food Service Program (SFSP).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Summer Food Service Program (SFSP). 250.62 Section 250... Program (NSLP) and Other Child Nutrition Programs § 250.62 Summer Food Service Program (SFSP). (a... meals to needy children primarily in the summer months, in their nonprofit food service programs...

7 CFR 250.62 - Summer Food Service Program (SFSP).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Summer Food Service Program (SFSP). 250.62 Section 250... Program (NSLP) and Other Child Nutrition Programs § 250.62 Summer Food Service Program (SFSP). (a... meals to needy children primarily in the summer months, in their nonprofit food service programs...

7 CFR 250.62 - Summer Food Service Program (SFSP).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Summer Food Service Program (SFSP). 250.62 Section 250... Program (NSLP) and Other Child Nutrition Programs § 250.62 Summer Food Service Program (SFSP). (a... meals to needy children primarily in the summer months, in their nonprofit food service programs...

Summer Splash. 1988 Wisconsin Summer Library Program Manual. Bulletin No. 8230.

ERIC Educational Resources Information Center

Lamb, Donald K.; And Others

A compilation of materials contributed by and developed with the cooperation of Wisconsin librarians and Ohio's 1987 summer reading program, this planning manual provides guidelines for planning and promoting summer programs for young people by librarians in the state of Wisconsin. The theme of the program, "Summer Splash," is intended…

Effective Summer Programming: What Educators and Policymakers Should Know

ERIC Educational Resources Information Center

McEachin, Andrew; Augustine, Catherine H.; McCombs, Jennifer

2018-01-01

The evidence suggests that many types of summer learning programs have the potential to reduce summer learning losses and perhaps create learning gains. However, implementing a summer program does not guarantee positive effects on students' learning. A key question then is: What factors make a summer learning program effective? This article, drawn…

Data Collecting using the MetalMapper in Dynamic Data Acquisition and Cued Modes TEMTADS Surveys at Redstone Arsenal, Huntsville, Alabama

DTIC Science & Technology

2017-06-20

inch mortars, large caliber projectiles (75-millimeter [mm] to 155-mm), and numerous types of bombs . With the exception of some areas north of RSA-312...scarring/craters are visible in RSA-073 in the Light Detection and Ranging data set. The MEC reportedly used in RSA-073 includes: AN-M76 bombs , PT1...incendiary mixture similar to Goop) filled; M47-type bombs , isobutyl methacrylate incendiary mix (IM-AE) and napalm filled; M69 bombs , IM-AE filled; 155

20 CFR 632.253 - Special operating provisions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.253... assistance from the summer program, and youth who remain in school but are likely to be confronted with... provided in the summer program at no cost, or at minimum cost, to the summer program; (d) Assure that...

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque, New Mexico Sponsored by: Air ...Summer Research Program Phillips Laboratory Sponsored by. Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico...UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8

Characteristics of effective summer learning programs in practice.

PubMed

Bell, Susanne R; Carrillo, Natalie

2007-01-01

The Center for Summer Learning examined various summer program models and found that there are nine characteristics that provide a framework for effective summer programs. In this chapter, the authors demonstrate how effective practices lead to positive results for young people. The nine characteristics of effective summer learning programs are (1) accelerating learning, (2) youth development, (3) proactive approach to summer learning, (4) leadership, (5) advanced planning, (6) staff development, (7) strategic partnerships, (8) evaluation and commitment to program improvement, and (9) sustainability and cost-effectiveness. These characteristics are divided into two sections. The first three characteristics address a program's approach to learning. Summer instructional techniques are most effective when academic learning is woven into enrichment activities and youth development. The second section covers program infrastructure to ensure the organization achieves and maintains quality programming. The nine characteristics complement each other to ensure a strong program that works to prevent summer learning loss and narrow the achievement gap. To demonstrate the variety of high-quality programs that include the nine characteristics, thirteen program profiles at the conclusion of the chapter each highlight one of the characteristics. These profiles show the various approaches that different summer programs have developed to accelerate academic achievement and promote positive development for young people in their communities.

Responsive polymer-based colloids for drug delivery and bioconversion

NASA Astrophysics Data System (ADS)

Kudina, Olena

Responsive polymer-based colloids (RPBC) are the colloidal structures containing responsive polymeric component which is able to adapt its physico-chemical properties to the environment by undergoing chemical and/or conformational changes. The goal of the dissertation is to develop and characterize several groups of RPBC with different morphological complexity and explore their potential in drug delivery and bioconversion. The role of RPBC morphology for these specific applications is discussed in details. Three groups of RPBC were fabricated: i. polymeric micelles; ii. mixed polymeric micelles; iii. hybrid polymer-inorganic particles. All fabricated RPBCs contain polymeric component in their structure. The dissertation investigates how the changes of the responsive polymeric component properties are reflected in morphologies of RPBC. The first group of RPBC, polymeric micelles, was formed by the self-assembly of amphiphilic invertible polymers (AIPs) synthesized in our group. AIPs self-assemble into invertible micellar assemblies (IMAs) in solvents of different polarity. In this work, IMAs ability to invert the structure as a response to the change in solvent polarity was demonstrated using 1H NMR spectroscopy and SANS. It was shown that the IMAs incorporate hydrophobic cargo either in the core or in the shell, depending on the chemical structure of cargo molecules. Following in vitro study demonstrates that loaded with drug (curcumin) IMAs are cytotoxic to osteosarcoma cells. Mixed polymeric micelles represent another, more complex, RPBC morphologies studied in the dissertation. Mixed micelles were fabricated from AIPs and amphiphilic oligomers synthesized from pyromellitic dianhydride, polyethylene glycol methyl ethers, and alkanols/cholesterol. The combination of selected AIP and oligomers based on cholesterol results in mixed micelles with an increased drug-loading capacity (from 10% w/w loaded curcumin in single component IMAs to 26%w/w in mixed micelles). Even more complex colloids are hybrid polymer-inorganic particles, the third RPBC group studied in dissertation. Material was designed as core--shell particles with superparamagnetic core engulfed by grafted polymer brushes. These particles were loaded with enzymes (cellulases), thus, are turned into enzymogels for cellulose bioconversion. The study demonstrates that such RPBCs can be used multiple times during hydrolysis and provide an about four-fold increase in glucose production in comparison to free enzymes.

Lunar plasma measurement by MAP-PACE onboard KAGUYA (SELENE)

NASA Astrophysics Data System (ADS)

Saito, Yoshifumi

Low energy charged particles around the Moon were vigorously observed by Moon orbiting satellites and plasma instrumentation placed on the lunar surface in 1960s and 1970s. Though there were some satellites that explored the Moon afterwards, most of them were dedicated to the global mapping of the lunar surface. KAGUYA(SELENE) is a Japanese lunar orbiter that studies the origin and evolution of the Moon by means of global mapping of element abundances, mineralogical composition, and surface geographical mapping from 100km altitude. KAGUYA was successfully launched on 14 September 2007 by HIIA launch vehicle from Tanegashima Space Center in Japan. KAGUYA was inserted into a circular lunar polar orbit of 100km altitude and started continuous observation in mid-December 2007. One of the fourteen science instruments MAP-PACE (MAgnetic field and Plasma experiment - Plasma energy Angle and Composition Experiment) was developed for the comprehensive three-dimensional plasma measurement around the Moon. MAP-PACE consists of 4 sensors: ESA (Electron Spectrum Analyzer)-S1, ESA-S2, IMA (Ion Mass Analyzer), and IEA (Ion Energy Analyzer). ESA-S1 and S2 measure the distribution function of low energy electrons below 15keV. IMA and IEA measure the distribution function of low energy ions below 28keV/q. IMA has an ability to discriminate the ion mass with high mass resolution. PACE sensors have been measuring solar wind, plasmas in the wake region of the Moon and plasmas in the Earth's magnetosphere. ESA sensors have discovered electron heating over magnetic anomalies on the lunar surface. ESA sensors have also observed electrons accelerated from the lunar surface in the wake region. PACE ion sensors have discovered new features of low energy ions around the Moon. IMA has discovered the existence of alkali ions that are originated from the lunar surface or lunar atmosphere and are picked up by the solar wind. IEA and IMA sensors discovered solar wind reflection by the Moon. PACE ion sensors also discovered that ions are rarefied over the magnetic anomaly on the lunar surface while electrons are heated. MAP-PACE has been revealing unexpectedly active plasma environment around the Moon.

Knowledge-Based Motion Control of AN Intelligent Mobile Autonomous System

NASA Astrophysics Data System (ADS)

Isik, Can

An Intelligent Mobile Autonomous System (IMAS), which is equipped with vision and low level sensors to cope with unknown obstacles, is modeled as a hierarchy of path planning and motion control. This dissertation concentrates on the lower level of this hierarchy (Pilot) with a knowledge-based controller. The basis of a theory of knowledge-based controllers is established, using the example of the Pilot level motion control of IMAS. In this context, the knowledge-based controller with a linguistic world concept is shown to be adequate for the minimum time control of an autonomous mobile robot motion. The Pilot level motion control of IMAS is approached in the framework of production systems. The three major components of the knowledge-based control that are included here are the hierarchies of the database, the rule base and the rule evaluator. The database, which is the representation of the state of the world, is organized as a semantic network, using a concept of minimal admissible vocabulary. The hierarchy of rule base is derived from the analytical formulation of minimum-time control of IMAS motion. The procedure introduced for rule derivation, which is called analytical model verbalization, utilizes the concept of causalities to describe the system behavior. A realistic analytical system model is developed and the minimum-time motion control in an obstacle strewn environment is decomposed to a hierarchy of motion planning and control. The conditions for the validity of the hierarchical problem decomposition are established, and the consistency of operation is maintained by detecting the long term conflicting decisions of the levels of the hierarchy. The imprecision in the world description is modeled using the theory of fuzzy sets. The method developed for the choice of the rule that prescribes the minimum-time motion control among the redundant set of applicable rules is explained and the usage of fuzzy set operators is justified. Also included in the dissertation are the description of the computer simulation of Pilot within the hierarchy of IMAS control and the simulated experiments that demonstrate the theoretical work.

Arterial territory-specific phosphorylated retinoblastoma protein species and CDK2 promote differences in the vascular smooth muscle cell response to mitogens

PubMed Central

Lange, Martin; Fujikawa, Tatsuya; Koulova, Anna; Kang, Sona; Griffin, Michael J; Lassaletta, Antonio D; Erat, Anna; Tobiasch, Edda; Bianchi, Cesario; Elmadhun, Nassrene; Sellke, Frank W; Usheva, Anny

2014-01-01

Despite recent advances in medical procedures, cardiovascular disease remains a clinical challenge and the leading cause of mortality in the western world. The condition causes progressive smooth muscle cell (SMC) dedifferentiation, proliferation, and migration that contribute to vascular restenosis. The incidence of disease of the internal mammary artery (IMA), however, is much lower than in nearly all other arteries. The etiology of this IMA disease resistance is not well understood. Here, using paired primary IMA and coronary artery SMCs, serum stimulation, siRNA knockdowns, and verifications in porcine vessels in vivo, we investigate the molecular mechanisms that could account for this increased disease resistance of internal mammary SMCs. We show that the residue-specific phosphorylation profile of the retinoblastoma tumor suppressor protein (Rb) appears to differ significantly between IMA and coronary artery SMCs in cultured human cells. We also report that the differential profile of Rb phosphorylation may follow as a consequence of differences in the content of cyclin-dependent kinase 2 (CDK2) and the CDK4 phosphorylation inhibitor p15. Finally, we present evidence that siRNA-mediated CDK2 knockdown alters the profile of Rb phosphorylation in coronary artery SMCs, as well as the proliferative response of these cells to mitogenic stimulation. The intrinsic functional and protein composition specificity of the SMCs population in the coronary artery may contribute to the increased prevalence of restenosis and atherosclerosis in the coronary arteries as compared with the internal mammary arteries. PMID:24240190

Kinetics and oxidative mechanism for H2O2-enhanced iron-mediated aeration (IMA) treatment of recalcitrant organic compounds in mature landfill leachate.

PubMed

Deng, Yang; Englehardt, James D

2009-09-30

A hydrogen peroxide (H(2)O(2))-enhanced iron (Fe(0))-mediated aeration (IMA) process has been recently demonstrated to effectively remove organic wastes from mature landfill leachate. In this paper, the kinetics and oxidative mechanisms of the enhanced IMA treatment were studied. Bench-scale full factorial tests were conducted in an orbital shaker reactor for treatment of a mature leachate with an initial chemical oxygen demand (COD) of 900-1200 mg/L. At the maximum aeration rate (8.3 mL air/min mL sample), process variables significantly influencing the rates of H(2)O(2) decay and COD removal were pH (3.0-8.0), initial H(2)O(2) doses (0.21-0.84 M), and Fe(0) surface area concentrations (0.06-0.30 m(2)/L). Empirical kinetic models were developed and verified for the degradation of H(2)O(2) and COD. High DO maintained by a high aeration rate slowed the H(2)O(2) self-decomposition, accelerated Fe(0) consumption, and enhanced the COD removal. In hydroxyl radical (OH*) scavenging tests, the rate of removal of glyoxylic acid (target compound) was not inhibited by the addition of para-chlorobenzoic acid (OH* scavenger) at pH 7.0-7.5, ruling out hydroxyl radical as the principal oxidant in neutral-weakly basic solution. These experimental results show that this enhanced IMA technology is a potential alternative for the treatment of high strength recalcitrant organic wastewaters.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiegelmann, T.; Solanki, S. K.; Barthol, P.

Magneto-static models may overcome some of the issues facing force-free magnetic field extrapolations. So far they have seen limited use and have faced problems when applied to quiet-Sun data. Here we present a first application to an active region. We use solar vector magnetic field measurements gathered by the IMaX polarimeter during the flight of the Sunrise balloon-borne solar observatory in 2013 June as boundary conditions for a magneto-static model of the higher solar atmosphere above an active region. The IMaX data are embedded in active region vector magnetograms observed with SDO /HMI. This work continues our magneto-static extrapolation approach,more » which was applied earlier to a quiet-Sun region observed with Sunrise I. In an active region the signal-to-noise-ratio in the measured Stokes parameters is considerably higher than in the quiet-Sun and consequently the IMaX measurements of the horizontal photospheric magnetic field allow us to specify the free parameters of the model in a special class of linear magneto-static equilibria. The high spatial resolution of IMaX (110–130 km, pixel size 40 km) enables us to model the non-force-free layer between the photosphere and the mid-chromosphere vertically by about 50 grid points. In our approach we can incorporate some aspects of the mixed beta layer of photosphere and chromosphere, e.g., taking a finite Lorentz force into account, which was not possible with lower-resolution photospheric measurements in the past. The linear model does not, however, permit us to model intrinsic nonlinear structures like strongly localized electric currents.« less

Decellularization of Human Internal Mammary Artery: Biomechanical Properties and Histopathological Evaluation.

PubMed

Kajbafzadeh, Abdol-Mohammad; Khorramirouz, Reza; Kameli, Seyede Maryam; Hashemi, Javad; Bagheri, Amin

2017-01-01

This study undertook to create small-diameter vascular grafts and assess their structure and mechanical properties to withstand arterial implantation. Twenty samples of intact human internal mammary arteries (IMAs) were collected and decellularized using detergent-based methods. To evaluate residual cellular and extracellular matrix (ECM) components, histological analysis was performed. Moreover, collagen typing and ECM structure were analyzed by Picrosirius red and Movat's pentachrome staining. Scanning electron microscopy was also applied to assess microarchitecture of both endothelial and adventitial surfaces of native and decellularized arterial samples. Furthermore, mechanical tests were performed to evaluate the rigidity and suture strength of the arteries. Human IMAs were completely decellularized in all three segments (proximal, middle, and distal). ECM proteins such as collagen and elastic fibers were efficiently preserved and no structural distortion in intima, media, and adventitial surfaces was observed. The parameters of the mechanical tests revealed no significant differences in the mechanical properties of decellularized arteries in comparison to native arteries with considerable strength, suture retention, and stress relaxation (Young's modulus [MPa] = 0.22 ± 0.023 [native] and 0.22 ± 0.015 [acellular]; and suture strength 0.56 ± 0.19 [native] vs. 0.56 ± 0.12 [acellular], respectively). Decellularized IMA represents a potential arterial scaffold as an alternative to autologous grafts for future arterial bypass surgeries. By this technique, microarchitecture and mechanical integrity of decellularized arteries were considerably similar to native arteries. The goal of this study was to introduce an efficient method for complete decellularization of human IMA and evaluate the ECM and biomechanical properties.

Emergency Immigration Education Act Programs: Summer E.S.L. Welcome Plus Program for Students of Limited English Proficiency (LEP), Summer Bilingual Program, and Project Omega. OREA Report.

ERIC Educational Resources Information Center

Duque, Diana L.

This report presents findings of the evaluation by the New York City public school system's Office of Research, Evaluation, and Assessment of three programs (Summer E.S.L. Welcome Plus, Summer Bilingual, and Project Omega) for immigrant students. The Summer E.S.L. (English as a Second Language) Welcome Plus program operated at 19 sites in New York…

Gifted Students' Perceptions of an Accelerated Summer Program and Social Support

ERIC Educational Resources Information Center

Lee, Seon-Young; Olszewski-Kubilius, Paula; Makel, Matthew C.; Putallaz, Martha

2015-01-01

Using survey responses from students who participated in the summer programs at two university-based gifted education institutions, this study examined changes in gifted students' perceptions of their learning environments, accelerated summer programs and regular schools, and social support in lives after participation in the summer programs. Our…

Extended plantar limb (modified) chevron osteotomy versus scarf osteotomy for hallux valgus correction: A randomised controlled trial.

PubMed

Mahadevan, Devendra; Lines, Stephen; Hepple, Stephen; Winson, Ian; Harries, William

2016-06-01

The purpose of this RCT was to compare the extended plantar limb (modified) chevron osteotomy with the scarf osteotomy in correcting hallux valgus deformity and improving functional scores and patient satisfaction. Patients were randomly assigned and kept blind to surgical allocation. Cases requiring additional procedures including the Akin osteotomy were excluded. Outcomes were measured at 1 year following surgery. 84 patients (109 feet) were analysed (60 modified chevron; 49 Scarf). The mean age was 50.7 years (75F: 9M). Post-operative intermetatarsal angle (IMA) was significantly lower in the modified chevron group (5.8° versus 6.9°, p=0.045). Hallux valgus angle and distal metatarsal articular angle were similar. The magnitude of IMA correction with the modified chevron was also significantly greater (9.1° versus 7.1°, p=0.007). Both osteotomies produced comparable MOxFQ scores and satisfaction ratings. The modified chevron was superior to the scarf osteotomy in correcting IMA in hallux valgus deformity. Copyright © 2015 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

Summer library reading programs.

PubMed

Fiore, Carole D

2007-01-01

Virtually all public libraries in the United States provide some type of summer library reading program during the traditional summer vacation period. Summer library reading programs provide opportunities for students of many ages and abilities to practice their reading skills and maintain skills that are developed during the school year. Fiore summarizes some of the research in the field and relates it to library programs and usage by students. Several traditional and innovative programs from U.S. and Canadian libraries are described. She concludes with a call for further research related to summer library reading programs.

Hunger Doesn't Take a Vacation: Summer Nutrition Status Report.

ERIC Educational Resources Information Center

Food Research and Action Center, Washington, DC.

This report describes the current status of the Summer Food Service Program (SFSP) and the National School Lunch Program (NSLP) (referred to in combination as the Summer Nutrition Programs), federal entitlement programs providing support for state and local efforts to offer low-income children nutritious summer meals and snacks during supervised…

Partitioning Strategy Using Static Analysis Techniques

NASA Astrophysics Data System (ADS)

Seo, Yongjin; Soo Kim, Hyeon

2016-08-01

Flight software is software used in satellites' on-board computers. It has requirements such as real time and reliability. The IMA architecture is used to satisfy these requirements. The IMA architecture has the concept of partitions and this affected the configuration of flight software. That is, situations occurred in which software that had been loaded on one system was divided into many partitions when being loaded. For new issues, existing studies use experience based partitioning methods. However, these methods have a problem that they cannot be reused. In this respect, this paper proposes a partitioning method that is reusable and consistent.

Thriller-Dillers & Chillers. Wisconsin Summer Library Program Manual, 1985. Bulletin No. 5212.

ERIC Educational Resources Information Center

Johnson, Debra Wilcox, Ed.

The Wisconsin Summer Library Program was developed to promote use of the library by children during the summer, to familiarize them with the resources of the public library, and to help them retain their reading skills over the summer. Different ways of interpreting the theme of the summer program for 1985 were suggested by librarians throughout…

The impact of serum adropin and ischemia modified albumin levels based on BMI in PCOS.

PubMed

Inal, Zeynep Ozturk; Erdem, Sami; Gederet, Yavuz; Duran, Cevdet; Kucukaydin, Zehra; Kurku, Huseyin; Sakarya, Derya Kilic

2018-02-21

The aim of this study was to evaluate the effects of polycystic ovary syndrome (PCOS) and body mass index (BMI) on serum adropin and ischemia modified albumin (IMA) levels. This prospective cross-sectional study was performed with a total of 120 women [group1; non-PCOS = 60 (BMI <25 = 30, BMI ≥25 = 30) and group 2; PCOS = 60 (BMI <25 = 30, BMI ≥25 = 30)]. Blood samples were collected between the third and fifth days of the women's menstrual cycles after a night of fasting. There were no differences between the groups in relation to age, basal follicle stimulating hormone, estradiol, thyroid stimulating hormone, prolactin, high-density lipoprotein cholesterol, total testosterone, dehydroepiandrosterone sulfate levels, systolic and diastolic blood pressures. A significant difference was found in basal luteinizing hormone, fasting glucose, insulin, homeostatic model assessment of insulin resistance, total cholesterol, low-density lipoprotein cholesterol, triglycerides, free testosterone levels, waist-to-hip ratios and the Ferriman-Gallwey scores between the PCOS and non-PCOS patients in the lean and overweight groups (p<0.05). The serum adropin levels in the lean PCOS group were lower than in the lean non-PCOS group (p<0.05) and were lower in the overweight PCOS group than in the overweight non-PCOS group (p<0.05). There was also a statistically significant difference in serum IMA levels in the PCOS group than in the non-PCOS group in both the lean and overweight groups (p<0.05). Although serum adropin levels were significantly decreased in the PCOS group, IMA levels increased. Further studies are needed to determine the effects of adropin and IMA in women with PCOS and to use a new marker to monitorize treatment outcomes.

Preoperative Planning and Intraoperative Technique for Accurate Translation of a Distal First Metatarsal Osteotomy.

PubMed

Wynes, Jacob; Lamm, Bradley M; Andrade, Bijan J; Malay, D Scot

2016-01-01

We used preoperative radiographic and intraoperative anatomic measurements to predict and achieve, respectively, the precise amount of capital fragment lateral translation required to restore anatomic balance to the first metatarsophalangeal joint. Correlation was used to relate the amount of capital fragment translation and operative reduction of the first intermetatarsal angle (IMA), hallux abductus angle (HAA), tibial sesamoid position (TSP), metatarsus adductus angle, and first metatarsal length. The mean capital fragment lateral translation was 5.54 ± 1.64 mm, and the mean radiographic reductions included a first IMA of 5.04° ± 2.85°, an HAA of 9.39° ± 8.38°, and a TSP of 1.38 ± 0.9. These changes were statistically (p < .001) and clinically (≥32.55%) significant. The mean reduction of the metatarsus adductus angle was 0.66° ± 4.44° and that for the first metatarsal length was 0.33 ± 7.27 mm, and neither of these were statistically (p = .5876 and 0.1247, respectively) or clinically (≤3.5%) significant. Pairwise correlations between the amount of lateral translation of the capital fragment and the first IMA, HAA, and TSP values were moderately positive and statistically significant (r = 0.4412, p = .0166; r = 0.5391, p = .0025; and r = 0.3729, p = .0463; respectively). In contrast, the correlation with metatarsus adductus and the first metatarsal shortening were weak and not statistically significant (r = 0.2296, p = .2308 and r = -0.2394, p = .2109, respectively). The results of our study indicate that predicted preoperative and executed intraoperative lateral translation of the capital fragment correlates with statistically and clinically significant reductions in the first IMA, HAA, and TSP. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Robotic Low Ligation of the Inferior Mesenteric Artery for Rectal Cancer Using the Firefly Technique.

PubMed

Bae, Sung Uk; Min, Byung Soh; Kim, Nam Kyu

2015-07-01

By integrating intraoperative near infrared fluorescence imaging into a robotic system, surgeons can identify the vascular anatomy in real-time with the technical advantages of robotics that is useful for meticulous lymphovascular dissection. Herein, we report our initial experience of robotic low ligation of the inferior mesenteric artery (IMA) with real-time identification of the vascular system for rectal cancer using the Firefly technique. The study group included 11 patients who underwent a robotic total mesorectal excision with preservation of the left colic artery for rectal cancer using the Firefly technique between July 2013 and December 2013. The procedures included five low anterior resections and six ultra-low anterior resections with loop ileostomy. The median total operation time was 327 min (226-490). The low ligation time was 10 min (6-20), and the time interval between indocyanine green injection and division of the sigmoid artery was 5 min (2-8). The estimated blood loss was 200 mL (100-500). The median time to soft diet was 4 days (4-5), and the median length of stay was 7 days (5-9). Three patients developed postoperative complications; one patients developed anal stricture, one developed ileus, and one developed non-complicated intraabdominal fluid collection. The median total number of lymph nodes harvested was 17 (9-29). Robotic low ligation of the IMA with real-time identification of the vascular system for rectal cancer using the Firefly technique is safe and feasible. This technique can allow for precise lymph node dissection along the IMA and facilitate the identification of the left colic branch of the IMA.

Operating theatre ventilation systems and microbial air contamination in total joint replacement surgery: results of the GISIO-ISChIA study.

PubMed

Agodi, A; Auxilia, F; Barchitta, M; Cristina, M L; D'Alessandro, D; Mura, I; Nobile, M; Pasquarella, C

2015-07-01

Recent studies have shown a higher rate of surgical site infections in hip prosthesis implantation using unidirectional airflow ventilation compared with turbulent ventilation. However, these studies did not measure the air microbial quality of operating theatres (OTs), and assumed it to be compliant with the recommended standards for this ventilation technique. To evaluate airborne microbial contamination in OTs during hip and knee replacement surgery, and compare the findings with values recommended for joint replacement surgery. Air samplings were performed in 28 OTs supplied with unidirectional, turbulent and mixed airflow ventilation. Samples were collected using passive sampling to determine the index of microbial air contamination (IMA). Active sampling was also performed in some of the OTs. The average number of people in the OT and the number of door openings during the sampling period were recorded. In total, 1228 elective prosthesis procedures (60.1% hip and 39.9% knee) were included in this study. Of passive samplings performed during surgical activity in unidirectional airflow ventilation OTs (U-OTs) and mixed airflow OTs (M-OTs), 58.9% and 87.6% had IMA values >2, respectively. Of samplings performed during surgical activity in turbulent airflow OTs (T-OTs) and in turbulent airflow OTs with the surgical team wearing Steri-Shield Turbo Helmets (TH-OTs), 8.6% and 60% had IMA values ≤ 2, respectively. Positive correlation was found between IMA values and the number of people in the OT and the number of door openings (P < 0.001). In addition, correlation was found between active and passive sampling (P < 0.001). These findings challenge the belief that unidirectional systems always provide acceptable airborne bacterial counts. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Differences between perivascular adipose tissue surrounding the heart and the internal mammary artery: possible role for the leptin-inflammation-fibrosis-hypoxia axis.

PubMed

Drosos, Ioannis; Chalikias, Georgios; Pavlaki, Maria; Kareli, Dimitra; Epitropou, Grigorios; Bougioukas, Georgios; Mikroulis, Dimitrios; Konstantinou, Fotios; Giatromanolaki, Alexandra; Ritis, Konstantinos; Münzel, Thomas; Tziakas, Dimitrios; Konstantinides, Stavros; Schäfer, Katrin

2016-11-01

The factors mediating the paracrine effects of perivascular adipose tissue (PVAT) in atherosclerosis are largely unknown. The adipokine leptin has been implicated in the increased cardiovascular risk in obesity and may locally promote neointima formation independently of circulating leptin levels. In patients with established coronary artery disease, we examined the expression of leptin as well as of its possible inducers in 'cardiac' PVAT surrounding the aortic root and coronary arteries (C-PVAT), and compared it to the PVAT surrounding the internal mammary artery (IMA-PVAT), a vessel resistant to atherosclerosis. Tissue specimens collected from male patients undergoing coronary artery bypass surgery were processed for real-time PCR, ELISA, in situ hybridization, and immunohistochemistry analysis. Leptin protein expression was elevated in C-PVAT compared to IMA-PVAT, independent of serum leptin levels. Compared to IMA-PVAT, C-PVAT exhibited more pronounced angiogenesis and inflammation, as indicated by significantly higher numbers of PECAM1-positive vessels and CD68-positive macrophages, and was characterized by a greater extent of fibrosis and hypoxia. Increased expression of hypoxia-inducible factor-1α and Fos-like antigen (FOSL)2, factors known to enhance leptin gene transcription, was observed in C-PVAT. As a proof of concept, exposure of human adipocytes to chemical hypoxia resulted in significantly increased FOSL2 and leptin mRNA levels. A higher degree of local tissue hypoxia and up-regulation of leptin expression in the perivascular adipose tissue, along with increased vascularization, inflammation, and fibrosis, may contribute to the increased atherosclerotic plaque burden in the coronary arteries compared to the IMA.

Comparative morphometric analysis of 5 interpositional arterial autograft options for adult living donor liver transplantation.

PubMed

Imakuma, E S; Bordini, A L; Millan, L S; Massarollo, P C B; Caldini, E T E G

2014-01-01

In living donor liver transplantation, the right-sided graft presents thin and short vessels, bringing forward a more difficult anastomosis. In these cases, an interpositional arterial autograft can be used to favor the performance of the arterial anastomosis, making the procedure easier and avoiding surgical complications. We compared the inferior mesenteric artery (IMA), the splenic artery (SA), the inferior epigastric artery (IEA), the descending branch of the lateral circumflex femoral artery (LCFA), and the proper hepatic artery (PHA) as options for interpositional autograft in living donor liver transplantation. Segments of at least 3 cm of all 5 arteries were harvested from 16 fresh adult cadavers from both genders through standardized dissection. The analyzed measures were proximal and distal diameter and length. The proximal diameter of the RHA and the distal diameter of the SA, IMA, IEA and the LCFA were compared to the distal diameter of the RHA. The proximal and distal diameters of the SA, IEA and LCFA were compared to study caliber gain of each artery. All arteries except the IMA showed statistical significant difference in relation to the RHA in terms of diameter. Regarding caliber gain, the arteries demonstrated statistical significant difference. All the harvested arteries except PHA were 3 cm in length. The IMA demonstrated the best compatibility with the RHA in terms of diameter and showed sufficient length to be employed as interpositional graft. The PHA, the SA, the IEA and the LCFA presented statistically significant different diameters when compared to the RHA. Among these vessels, only the PHA did not show sufficient mean length. Copyright © 2014 Elsevier Inc. All rights reserved.

Extrahepatic Blood Supply to Hepatocellular Carcinoma: Angiographic Demonstration and Transcatheter Arterial Chemoembolization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miyayama, Shiro; Matsui, Osamu; Taki, Keiichi

2006-02-15

Purpose. To evaluate the incidence of each extrahepatic collateral pathway to hepatocellular carcinoma (HCC) and to assess technical success rates and complications of transcatheter arterial chemoembolization (TACE) through each collateral. Methods. We retrospective evaluated extrahepatic collateral pathways to HCC on angiography in 386 procedures on 181 consecutive patients. One hundred and seventy patients had previously undergone TACE. TACE through extrahepatic collaterals using iodized oil and gelatin sponge particles was performed when a catheter was advanced into the tumor-feeding branch to avoid nontarget embolization. Results. A single collateral was revealed in 275 TACE procedures, two were revealed in 74, and threemore » or more were revealed in 34. Incidences of collateral source to HCC were 83% from the right inferior phrenic artery (IPA), 24% from the cystic artery, 13% from the omental artery, 12% from the right renal capsular artery (RCA) and left IPA, 8% from the right internal mammary artery (IMA) and right intercostal artery (ICA), and 7% from the right inferior adrenal artery (IAA). Technical success rates of TACE were 53% in the right ICA, 70% in the cystic artery, 74% in the omental artery, 93% in the left IPA, 96% in the right IPA, and 100% in the right RCA, right IMA, and right IAA. Complications included skin necrosis after TACE through the right IMA (n = 1), cholecystitis after TACE through the cystic artery (n = 1), and ulcer formation after TACE through the right gastric artery (n = 1), in addition to pleural effusion and basal atelectasis after TACE through the IPA and IMA. Conclusion. Our study suggests that TACE through extrahepatic collaterals is possible with high success rates, and is also relatively safe.« less

Coronary bypass graft patency in patients with diabetes in the Bypass Angioplasty Revascularization Investigation (BARI).

PubMed

Schwartz, Leonard; Kip, Kevin E; Frye, Robert L; Alderman, Edwin L; Schaff, Hartzell V; Detre, Katherine M

2002-11-19

Few studies have compared long-term status of bypass grafts between patients with and without diabetes, and uncertainty exists as to whether diabetes independently predicts poor clinical outcome after CABG. Among 1526 patients in BARI who underwent CABG as initial revascularization, 99 of 292 (34%) with treated diabetes mellitus (TDM) (those on insulin or oral hypoglycemic agents) and 469 of 1234 (38%) without TDM had follow-up angiography. Angiograms with the longest interval from initial surgery and before any percutaneous graft intervention (mean 3.9 years) were reviewed. An average of 3.0 grafts were placed at initial CABG for patients with TDM (n=297; internal mammary artery [IMA], 33%) and 2.9 grafts for patients without TDM (n=1347; IMA, 34%). Patients with TDM were more likely than those without to have small (<1.5 mm) grafted distal vessels (29% versus 22%) and vessels of poor quality (9% versus 6%). On follow-up angiography, 89% of IMA grafts were free of stenoses > or =50% among patients with TDM versus 85% among patients without TDM (P=0.23). For vein grafts, the corresponding percentages were 71% versus 75% (P=0.40). After statistical adjustment, TDM was unrelated to having a graft stenosis > or =50% (adjusted odds ratio, 0.87; 95% CI, 0.58 to 1.32). Despite diabetic patients' having smaller distal vessels and vessels judged to be of poorer quality, diabetes does not appear to adversely affect patency of IMA or vein grafts over an average of 4-year follow-up. Previously observed differences in survival between CABG-treated patients with and without diabetes may be largely a result of differential risk of mortality from noncardiac causes.

Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the TES gene in endothelial cell functions relevant to coronary artery disease.

PubMed

Archacki, Stephen R; Angheloiu, George; Moravec, Christine S; Liu, Hui; Topol, Eric J; Wang, Qing Kenneth

2012-03-15

Coronary artery disease (CAD) is the leading cause of death worldwide. It has been established that internal mammary arteries (IMA) are resistant to the development of atherosclerosis, whereas left anterior descending (LAD) coronary arteries are athero-prone. The contrasting properties of these two arteries provide an innovative strategy to identify the genes that play important roles in the development of atherosclerosis. We carried out microarray analysis to identify genes differentially expressed between IMA and LAD. Twenty-nine genes showed significant differences in their expression levels between IMA and LAD, which included the TES gene encoding Testin. The role of TES in the cardiovascular system is unknown. Here we show that TES is involved in endothelial cell (EC) functions relevant to atherosclerosis. Western blot analysis showed higher TES expression in IMA than in LAD. Reverse transcription polymerase chain reaction and western blot analyses showed that TES was consistently and markedly down-regulated by more than 6-fold at both mRNA and protein levels in patients with CAD compared with controls without CAD (P= 0.000049). The data suggest that reduced TES expression is associated with the development of CAD. Knockdown of TES expression by small-interfering RNA promoted oxidized-LDL-mediated monocyte adhesion to ECs, EC migration and the transendothelial migration of monocytes, while the over-expression of TES in ECs blunted these processes. These results demonstrate association between reduced TES expression and CAD, establish a novel role for TES in EC functions and raise the possibility that reduced TES expression increases susceptibility to the development of CAD.

Peterson's Summer Study Abroad: A Guide to Summer Academic and Language Programs. First Edition.

ERIC Educational Resources Information Center

Peterson's Guides, Inc., Princeton, NJ.

This guide provides descriptions of over 900 summer academic and language study-abroad programs in 80 countries that range from 1-week language study courses to full-summer university programs. An introductory section provides general information on study abroad programs and the use of the guide. The bulk of the guide consists of individual…

IMGui-A Desktop GUI Application for Isolation with Migration Analyses.

PubMed

Knoblauch, Jared; Sethuraman, Arun; Hey, Jody

2017-02-01

The Isolation with Migration (IM) programs (e.g., IMa2) have been utilized extensively by evolutionary biologists for model-based inference of demographic parameters including effective population sizes, migration rates, and divergence times. Here, we describe a graphical user interface for the latest IM program. IMGui provides a comprehensive set of tools for performing demographic analyses, tracking progress of runs, and visualizing results. Developed using node. js and the Electron framework, IMGui is an application that runs on any desktop operating system, and is available for download at https://github.com/jaredgk/IMgui-electron-packages. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Resettlement experiences and resilience in refugee youth in Perth, Western Australia.

PubMed

Earnest, Jaya; Mansi, Ruth; Bayati, Sara; Earnest, Joel Anthony; Thompson, Sandra C

2015-06-10

In Australia, the two major pathways of refugee entry are the United Nations High Commissioner for Refugees resettlement programme and irregular maritime arrivals (IMAs) seeking asylum. The Australian Government's policies towards IMAs since July 2013 are controversial, uncompromising and consistently harsh, with asylum seekers held in detention centres for prolonged periods. Refugees and asylum seekers have distinct and unique stressors that make resettlement difficult. This exploratory study examines resettlement experiences for refugee youth in Western Australia using the psychosocial conceptual framework and qualitative methods. Focus group discussions and key informant interviews were undertaken with verbatim transcripts analysed using thematic analysis to identify themes. Themes documented that language and its impact, and experience with education, health, and social activities, support structures provided to youth and supporting future aspirations as critical to successful resettlement. This exploratory study contributes to developing a broader understanding of the resettlement experiences of refugee youth, drawing on their current and past experiences, cultural differences and mechanisms for coping. Fluency in English language, especially spoken, was a facilitator of successful resettlement. Our results align with previous studies documenting that support programs are vital for successful resettlement. Although faced with immense difficulties refugee youth are resilient, want to succeed and have aspirations for the future. Strategies and recommendations suggested by refugee youth themselves could be used for developing interventions to assist successful resettlement.

NASA-ASEE Summer Faculty Fellowship Program at NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Prahl, Joseph M.; Keith, Theo G., Jr.; Montegani, Francis J.

1996-01-01

During the summer of 1996, a ten-week Summer Faculty Fellowship Program was conducted at the NASA Lewis Research Center (LeRC) in collaboration with Case Western Reserve University (CWRU), and the Ohio Aerospace Institute (OAI). This is the thirty-third summer of this program at Lewis. It was one of nine summer programs sponsored by NASA in 1996, at various field centers under the auspices of the American Society for Engineering Education (ASEE). The objectives of the program are: (1) to further the professional knowledge of qualified engineering and science educators, (2) to stimulate an exchange of ideas between participants and NASA, (3) to enrich and refresh the research activities of participants' institutions. (4) to contribute to the research objectives of LeRC. This report is intended to recapitulate the activities comprising the 1996 Lewis Summer Faculty Fellowship Program, to summarize evaluations by the participants, and to make recommendations regarding future programs.

The Study of Summer Reading Programs in Response to House Joint Resolution 423. Report of the Department of Education to the Governor and the General Assembly of Virginia. House Document No. 24.

ERIC Educational Resources Information Center

Virginia State Dept. of Education, Richmond.

A study investigated the feasibility of compulsory summer reading programs for students at risk in Virgina school divisions were surveyed concerning their summer school offerings. Remedial summer school enrollment statewide was analyzed. Structured interviews with staff responsible for administration of summer reading programs from 16 selected…

Start a Summer Arts Program.

ERIC Educational Resources Information Center

Pedersen, Kirie

1984-01-01

Tips on organizing a creative teaching experience for summer vacation time are offered. Program organization, student selection, course content, publicity, and funding are aspects to be considered when planning a summer arts program. (DF)

Endovascular Treatment of Totally Occluded Superior Mesenteric Artery by Retrograde Crossing via the Villemin Arcade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferro, Carlo; Rossi, Umberto G., E-mail: urossi76@hotmail.com; Seitun, Sara

2013-06-15

Chronic mesenteric ischemia (CMI) is a rare disorder that is commonly caused by progressive atherosclerotic stenosis or occlusion of one or more mesenteric arteries. Endovascular treatment for symptomatic CMI represents a viable option, especially in high-operative risk patients. We report a case of acute symptomatic CMI with chronic totally occlusion of the superior mesenteric artery (SMA) associated with significant stenosis of celiac trunk (CT) and inferior mesenteric artery (IMA) that underwent endovascular treatment of all the three mesenteric arteries: stenting of CT and IMA stenosis, and recanalization of the SMA occlusion by retrograde crossing via the Villemin arcade.

High tie versus low tie of the inferior mesenteric artery in colorectal cancer: A meta-analysis.

PubMed

Yang, Yafan; Wang, Guiying; He, Jingli; Zhang, Jianfeng; Xi, Jinchuan; Wang, Feifei

2018-04-01

Colorectal cancer surgery includes "high tie" and "low tie"of the inferior mesenteric artery(IMA). However, different ligation level is closely related to the blood supply of anastomosis, which may increase the leakage rate, and it is unclear which technique confers a lower anastomotic leakage rate(AL) and survival advantage. To compare the effectiveness and impact of inferior mesenteric artery (IMA) high ligation versus IMA low ligation on anastomotic leakage, lymph nodes yield rates and 5-year survival. A list of these studies, published in English from 1990 to 2017, was obtained independently by two reviewers from databases such as PubMed, Medline, ScienceDirect and Web of Science. Anastomotic leakage rate, the yield of lymph nodes and 5-year survival were compared using Review Manager 5.3. There was no significant difference in anastomotic leakage, number of lymph nodes retrieved and 5-year survival rate for both techniques. Neither the high tie nor the low tie strategy has an evidence in terms of anastomotic leakage rate, harvested lymph nodes, and the 5-year survival rate. Further RCT is needed. Copyright © 2018 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

An AFDX Network for Spacecraft Data Handling

NASA Astrophysics Data System (ADS)

Deredempt, Marie-Helene; Kollias, Vangelis; Sun, Zhili; Canamares, Ernest; Ricco, Philippe

2014-08-01

In aeronautical domain, ARINC-664 Part 7 specification (AFDX) [4] provides the enabling technology for interfacing equipment in Integrated Modular Avionics (IMA) architectures. The complementary part of AFDX for a complete interoperability - Time and Space Partitioning (ARINC 653) concepts [1]- was already studied as part of space domain ESA roadmap (i.e. IMA4Space project)Standardized IMA based architecture is already considered in aeronautical domain as more flexible, reliable and secure. Integration and validation become simple, using a common set of tools and data base and could be done by part on different means with the same definition (hardware and software test benches, flight control or alarm test benches, simulator and flight test installation).In some area, requirements in terms of data processing are quite similar in space domain and the concept could be applicable to take benefit of the technology itself and of the panel of hardware and software solutions and tools available on the market. The Mission project (Methodology and assessment for the applicability of ARINC-664 (AFDX) in Satellite/Spacecraft on-board communicatION networks), as an FP7 initiative for bringing terrestrial SME research into the space domain started to evaluate the applicability of the standard in space domain.

DNA Barcoding Reveals Cryptic Diversity within Commercially Exploited Indo-Malay Carangidae (Teleosteii: Perciformes)

PubMed Central

Mat Jaafar, Tun Nurul Aimi; Taylor, Martin I.; Mohd Nor, Siti Azizah; de Bruyn, Mark; Carvalho, Gary R.

2012-01-01

Background DNA barcodes, typically focusing on the cytochrome oxidase I gene (COI) in many animals, have been used widely as a species-identification tool. The ability of DNA barcoding to distinguish species from a range of taxa and to reveal cryptic species has been well documented. Despite the wealth of DNA barcode data for fish from many temperate regions, there are relatively few available from the Southeast Asian region. Here, we target the marine fish Family Carangidae, one of the most commercially-important families from the Indo-Malay Archipelago (IMA), to produce an initial reference DNA barcode library. Methodology/Principal Findings Here, a 652 bp region of COI was sequenced for 723 individuals from 36 putative species of Family Carangidae distributed within IMA waters. Within the newly-generated dataset, three described species exhibited conspecific divergences up to ten times greater (4.32–4.82%) than mean estimates (0.24–0.39%), indicating a discrepancy with assigned morphological taxonomic identification, and the existence of cryptic species. Variability of the mitochondrial DNA COI region was compared within and among species to evaluate the COI region's suitability for species identification. The trend in range of mean K2P distances observed was generally in accordance with expectations based on taxonomic hierarchy: 0% to 4.82% between individuals within species, 0% to 16.4% between species within genera, and 8.64% to 25.39% between genera within families. The average Kimura 2-parameter (K2P) distance between individuals, between species within genera, and between genera within family were 0.37%, 10.53% and 16.56%, respectively. All described species formed monophyletic clusters in the Neighbour-joining phylogenetic tree, although three species representing complexes of six potential cryptic species were detected in Indo-Malay Carangidae; Atule mate, Selar crumenophthalmus and Seriolina nigrofasciata. Conclusion/Significance This study confirms that COI is an effective tool for species identification of Carangidae from the IMA. There were moderate levels of cryptic diversity among putative species within the central IMA. However, to explain the hypothesis of species richness in the IMA, it is necessary to sample the whole family across their broad geographic range. Such insights are helpful not only to document mechanisms driving diversification and recruitment in Carangidae, but also to provide a scientific framework for management strategies and conservation of commercially-important fisheries resources. PMID:23209586

Undergraduate Summer Research Programs and Graduate School Outcomes: Don't Ignore Rejected Program Applicants

ERIC Educational Resources Information Center

Sibulkin, Amy E.; Butler, J. S.

2015-01-01

We tracked a sample of primarily Black psychology baccalaureates' advanced degree enrollments and completions and estimated the association of those outcomes with summer research experience by merging three data sets: (a) summer research program participants, (b) a comparison group of alumni, mostly without summer research, and (c) degree…

76 FR 59182 - Bureau of Educational and Cultural Affairs; Exchange Visitor Program; Summer Work Travel Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

... Visitor Program; Summer Work Travel Program Sponsor On-Site Reviews ACTION: Notice. SUMMARY: Pursuant to..., the Department announces its intent to conduct on- site reviews of sponsors in the Summer Work Travel... Work Travel Program provides foreign college and university students the opportunity to work and travel...

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults.

PubMed

Risacher, Shannon L; McDonald, Brenna C; Tallman, Eileen F; West, John D; Farlow, Martin R; Unverzagt, Fredrick W; Gao, Sujuan; Boustani, Malaz; Crane, Paul K; Petersen, Ronald C; Jack, Clifford R; Jagust, William J; Aisen, Paul S; Weiner, Michael W; Saykin, Andrew J

2016-06-01

The use of anticholinergic (AC) medication is linked to cognitive impairment and an increased risk of dementia. To our knowledge, this is the first study to investigate the association between AC medication use and neuroimaging biomarkers of brain metabolism and atrophy as a proxy for understanding the underlying biology of the clinical effects of AC medications. To assess the association between AC medication use and cognition, glucose metabolism, and brain atrophy in cognitively normal older adults from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Indiana Memory and Aging Study (IMAS). The ADNI and IMAS are longitudinal studies with cognitive, neuroimaging, and other data collected at regular intervals in clinical and academic research settings. For the participants in the ADNI, visits are repeated 3, 6, and 12 months after the baseline visit and then annually. For the participants in the IMAS, visits are repeated every 18 months after the baseline visit (402 cognitively normal older adults in the ADNI and 49 cognitively normal older adults in the IMAS were included in the present analysis). Participants were either taking (hereafter referred to as the AC+ participants [52 from the ADNI and 8 from the IMAS]) or not taking (hereafter referred to as the AC- participants [350 from the ADNI and 41 from the IMAS]) at least 1 medication with medium or high AC activity. Data analysis for this study was performed in November 2015. Cognitive scores, mean fludeoxyglucose F 18 standardized uptake value ratio (participants from the ADNI only), and brain atrophy measures from structural magnetic resonance imaging were compared between AC+ participants and AC- participants after adjusting for potential confounders. The total AC burden score was calculated and was related to target measures. The association of AC use and longitudinal clinical decline (mean [SD] follow-up period, 32.1 [24.7] months [range, 6-108 months]) was examined using Cox regression. The 52 AC+ participants (mean [SD] age, 73.3 [6.6] years) from the ADNI showed lower mean scores on Weschler Memory Scale-Revised Logical Memory Immediate Recall (raw mean scores: 13.27 for AC+ participants and 14.16 for AC- participants; P = .04) and the Trail Making Test Part B (raw mean scores: 97.85 seconds for AC+ participants and 82.61 seconds for AC- participants; P = .04) and a lower executive function composite score (raw mean scores: 0.58 for AC+ participants and 0.78 for AC- participants; P = .04) than the 350 AC- participants (mean [SD] age, 73.3 [5.8] years) from the ADNI. Reduced total cortical volume and temporal lobe cortical thickness and greater lateral ventricle and inferior lateral ventricle volumes were seen in the AC+ participants relative to the AC- participants. The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus, use of AC medication among older adults should likely be discouraged if alternative therapies are available.

Outer Space...Calling All Readers. 1991 Summer Reading Program Manual.

ERIC Educational Resources Information Center

North Carolina State Dept. of Cultural Resources, Raleigh. Div. of State Library.

This manual provides guidelines and materials for librarians planning a summer reading program for children in North Carolina on the theme of outer space. An evaluation form to be returned to the State Library of North Carolina at the end of the summer is included. The introduction includes discussions of summer reading materials and programs;…

Summer Training and Education Program (STEP): Report on the 1985 Summer Experience. Executive Summary.

ERIC Educational Resources Information Center

Branch, Alvia Y.

The Summer Training and Education Program (STEP) provides 14 and 15 year olds with a paid summer experience that combines work, remediation in reading and math, and life skills instruction. This national, federally funded program is a response to data which show that poor academic performance and teenage pregnancy are important contributors to…

Idea Bank: Summer Music Programs for Students.

ERIC Educational Resources Information Center

Anderson, Tom; And Others

1989-01-01

Describes the elements of high quality summer music programs for students. Points out considerations for selection of a summer music camp, including setting daily schedule, amount of performance and private lessons, cost, faculty, and program scope. (LS)

HBCU Summer Undergraduate Training Program in Prostate Cancer: A Partnership Between USU-CPDR and UDC

DTIC Science & Technology

2015-10-02

conferences. 3 BODY Task 1: Selection Process: USU-CPDR summer internship program announcements for 2015 were made at the UDC through...AD_________________ Award Number: W81XWH-14-2-0142 TITLE: HBCU Summer Undergraduate Training Program in Prostate Cancer: A Partnership Between...DATES COVERED (From - To) 30 Sep 2014 - 29 Sep 2015 4. TITLE AND SUBTITLE: HBCU Summer Undergraduate Training Program in Prostate Cancer: A Partnership

78 FR 13141 - 30-Day Notice of Proposed Information Collection: Exchange Visitor Program Participant Survey...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-26

...: Exchange Visitor Program Participant Survey--Summer Work Travel ACTION: Notice of request for public... of Information Collection: Exchange Visitor Program Participant Survey--Summer Work Travel Program... participants in the Summer Work Travel category. Estimated Number of Respondents: 109,000. Estimated Number of...

How I Spent My Summer Vacation: Amazing Opportunities for Teachers

ERIC Educational Resources Information Center

Curwood, Jen Scott

2008-01-01

From summer programs in archaeology or Russian to teaching abroad for a year or more, there are many opportunities available for teachers. This article describes unique programs in archeology, geology, astronomy, botany, and oceanography that are available as summer programs; master's programs in languages, administration, writing, and Teaching…

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 2, Phillips Laboratory

DTIC Science & Technology

1994-11-01

Research Extension Program Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base, Washington, D.C. and Arkansas Tech University...Summer Research Extension Program (SREP) Phillips

United States Air Force Summer Research Program -- 1993. Volume 8. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque. New Mexico Sponsored by...Best Available Copy UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8 PHILLIPS LABORATORY ...Alabama Box 870344 Tuscaloosa, AL 35487-0344 Final Report for: Graduate Student Research Program Phillips Laboratory , Hanscom AFB Sponsored by: Air

Community-Based Summer Learning Programs for School- Age Children: Research-to-Policy Resources

ERIC Educational Resources Information Center

Stephens, Samuel A.

2016-01-01

Summer learning experiences for school-age children can be provided in a variety of ways and settings, including summer school programs (often remedial), community-based programs (often a continuation of afterschool programs), and home-based programs (in which families are provided with information and resources to encourage reading, often run by…

Summer-Jobs-for-Youth Program Guide. How to Develop and Manage a Summer Youth Jobs Program. A Technical Assistance Guide.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This guide offers a practical approach for operating summer youth employment programs that involves cooperation among private businesses and local organizations. A timetable provides a month-by-month schedule. Seven sections discuss management responsibilities. Program Planning covers scope, goals, and coordination. Program Management addresses…

Making Summer Count: How Summer Programs Can Boost Children's Learning

ERIC Educational Resources Information Center

McCombs, Jennifer Sloan; Augustine, Catherine; Schwartz, Heather; Bodilly, Susan; McInnis, Brian; Lichter, Dahlia; Cross, Amanda Brown

2012-01-01

During summer vacation, many students lose knowledge and skills. By the end of summer, students perform, on average, one month behind where they left off in the spring. Participation in summer learning programs should mitigate learning loss and could even produce achievement gains. Indeed, educators and policymakers increasingly promote summer…

Perspective Transformation through College Summer Service Immersion Programs: Is Learning Enhanced by Sustained Engagement?

ERIC Educational Resources Information Center

Hudson, Tara D.; Serra, Susan; Shappell, Andrea Smith; Gray-Girton, Angela; Brandenberger, Jay

2017-01-01

Summer offers the opportunity for sustained community engagement through immersions in summer service-learning programs. A group of 16 colleges and universities that sponsor domestic and international summer service initiatives have formed a Summer Service Collaborative (SSC) to enhance preparation, immersion, and follow-up in light of the unique…

20 CFR 632.261 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.261 Reporting requirements. (a) Each Native American grantee shall submit an end of summer report which will include both... than 45 days after the end of the summer program. ...

20 CFR 632.261 - Reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.261 Reporting requirements. (a) Each Native American grantee shall submit an end of summer report which will include both... than 45 days after the end of the summer program. ...

20 CFR 632.261 - Reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.261 Reporting requirements. (a) Each Native American grantee shall submit an end of summer report which will include both... than 45 days after the end of the summer program. ...

Sizzling Summer Reading Programs for Young Adults: Second Edition

ERIC Educational Resources Information Center

Kan, Katharine L.

2006-01-01

Summer reading programs are a staple in libraries nationwide and provide a valuable service: keeping teens productive and occupied when they are no longer busy in school. Producing creative programs at the library can be challenging when faced with this easily distracted teen demographic; that's where "Sizzling Summer Reading Programs" steps in.…

Supporting Students through Participation in the Regional High School Summer School Program

ERIC Educational Resources Information Center

Zhao, Huafang; McGaughey, Trisha A.; Wade, Julie

2014-01-01

The Office of Shared Accountability (OSA) in Montgomery County (Maryland) Public Schools (MCPS) conducted a study of the MCPS Regional High School Summer School Program. Academic intervention programs (AIPs) in MCPS, including the Regional High School Summer School Program, aim to help students gain lost credits and earn credits needed for…

Acquisition of Autonomous Behaviors by Robotic Assistants

NASA Technical Reports Server (NTRS)

Peters, R. A., II; Sarkar, N.; Bodenheimer, R. E.; Brown, E.; Campbell, C.; Hambuchen, K.; Johnson, C.; Koku, A. B.; Nilas, P.; Peng, J.

2005-01-01

Our research achievements under the NASA-JSC grant contributed significantly in the following areas. Multi-agent based robot control architecture called the Intelligent Machine Architecture (IMA) : The Vanderbilt team received a Space Act Award for this research from NASA JSC in October 2004. Cognitive Control and the Self Agent : Cognitive control in human is the ability to consciously manipulate thoughts and behaviors using attention to deal with conflicting goals and demands. We have been updating the IMA Self Agent towards this goal. If opportunity arises, we would like to work with NASA to empower Robonaut to do cognitive control. Applications 1. SES for Robonaut, 2. Robonaut Fault Diagnostic System, 3. ISAC Behavior Generation and Learning, 4. Segway Research.

Education in Summer: 100 Years at UW-Madison.

ERIC Educational Resources Information Center

Wisconsin Univ., Madison.

College summer sessions, and specifically the summer program at the University of Wisconsin-Madison between 1885-1985 are discussed in two papers and a conference summary. In "History of Summer School at the University of Wisconsin," John W. Jenkins and Barry J. Teicher examine the emergence and nature of summer programs in the context of the…

Can a Strategic Pipeline Initiative Increase the Number of Women and Underrepresented Minorities in Orthopaedic Surgery?

PubMed

Mason, Bonnie S; Ross, William; Ortega, Gezzer; Chambers, Monique C; Parks, Michael L

2016-09-01

Women and minorities remain underrepresented in orthopaedic surgery. In an attempt to increase the diversity of those entering the physician workforce, Nth Dimensions implemented a targeted pipeline curriculum that includes the Orthopaedic Summer Internship Program. The program exposes medical students to the specialty of orthopaedic surgery and equips students to be competitive applicants to orthopaedic surgery residency programs. The effect of this program on women and underrepresented minority applicants to orthopaedic residencies is highlighted in this article. (1) For women we asked: is completing the Orthopaedic Summer Internship Program associated with higher odds of applying to orthopaedic surgery residency? (2) For underrepresented minorities, is completing the Orthopaedic Summer Internship Program associated with higher odds of applying to orthopaedic residency? Between 2005 and 2012, 118 students completed the Nth Dimensions/American Academy of Orthopaedic Surgeons Orthopaedic Summer Internship Program. The summer internship consisted of an 8-week clinical and research program between the first and second years of medical school and included a series of musculoskeletal lectures, hands-on, practical workshops, presentation of a completed research project, ongoing mentoring, professional development, and counselling through each participant's subsequent years of medical school. In correlation with available national application data, residency application data were obtained for those Orthopaedic Summer Internship Program participants who applied to the match between 2011 through 2014. For these 4 cohort years, we evaluated whether this program was associated with increased odds of applying to orthopaedic surgery residency compared with national controls. For the same four cohorts, we evaluated whether underrepresented minority students who completed the program had increased odds of applying to an orthopaedic surgery residency compared with national controls. Fifty Orthopaedic Summer Internship scholars applied for an orthopaedic residency position. For women, completion of the Orthopaedic Summer Internship was associated with increased odds of applying to orthopaedic surgery residency (after summer internship: nine of 17 [35%]; national controls: 800 of 78,316 [1%]; odds ratio [OR], 51.3; 95% confidence interval [CI], 21.1-122.0; p < 0.001). Similarly, for underrepresented minorities, Orthopaedic Summer Internship completion was also associated with increased odds of orthopaedic applications from 2011 to 2014 (after Orthopaedic Summer Internship: 15 of 48 [31%]; non-Orthopaedic Summer Internship applicants nationally: 782 of 25,676 [3%]; OR, 14.5 [7.3-27.5]; p < 0.001). Completion of the Nth Dimensions Orthopaedic Summer Internship Program has a positive impact on increasing the odds of each student participant applying to an orthopaedic surgery residency program. This program may be a key factor in contributing to the pipeline of women and underrepresented minorities into orthopaedic surgery. Level III, therapeutic study.

The Effects of the Elevate Math Summer Program on Math Achievement and Algebra Readiness. REL 2015-096

ERIC Educational Resources Information Center

Snipes, Jason; Huang, Chun-Wei; Jaquet, Karina; Finkelstein, Neal

2015-01-01

The Effects of the Elevate Math summer program on math achievement and algebra readiness: This randomized trial examined the effects of the Elevate Math summer program on math achievement and algebra readiness, as well as math interest and self-efficacy, among rising 8th grade students in California's Silicon Valley. The Elevate Math summer math…

Final Report of the Evaluation of the Summer Program for Mentally Retarded Young Adults--Occupational Training Centers. Summer 1970. ESEA Title I.

ERIC Educational Resources Information Center

Nalven, Fredric; Oliver, Adela

The 1970 Summer Program for Mentally Retarded Young Adults Occupational Training Centers program, funded under Title I of the 1965 Elementary Secondary Education Act, was designed to serve the summer educational, prevocational, and social needs of approximately 170 retarded adolescents and young adults. The general objectives of the project were…

Science Immersion

ERIC Educational Resources Information Center

Burgin, Stephen R.; Sadler, Troy D.

2013-01-01

This article describes summer programs that allow high school students to participate in an "authentic scientific research experience" (ASRE). These summer programs are specifically designed to embed students in working laboratories and research groups. Summer ASRE programs for secondary learners range in length from a couple of weeks to…

United States Air Force Summer Research Program -- 1992 High School Apprenticeship Program (HSAP) Reports. Volume 13. Phillips Laboratory

DTIC Science & Technology

1992-01-01

Research Program Phillips Laboratory I4oJ A*6Iv4 Sponsored by: Air Force Office of Scientific Research Kirtland Air ...UNITED STATES AIR FORCE SUMMER RESEARCH PROGki"A -- 1992 HIGH SCHOOL APPRENTICESHIP PROGRAM (HSAP) REPORTS VOLUME 13 (t PHILLIPS LABORATORY . RESEARCH ...Arlington High School Final Report for: Summer Research Program Geophysics Directorate Phillips Laboratory

USAF/SCEEE Graduate Student Summer Support Program (1982). Management and Technical Report.

DTIC Science & Technology

1982-10-01

AD-A130 767 USAF/SCEEE GRADUATE STUDENT SUMMER SUPPORT PROGRAM (1982) MANAGEMENT AND..(U) SOUTHEASTERN CENTER FORELECTRICAL ENGINEERING EDUCATION INC...SUMMER SUPPORT PROGRAM Conducted by Southeastern Center for Electrical Engineering Education under USAF Contract Number F49620-82-C-0035 MANAGEMENT ...UNITED STATES AIR FORCE GRADUATE STUDENT SL24MER SUPPORT PROGRAM 1982 PROGRAM MANAGEMENT AND TECHNICAL REPORT SOUTHEASTERN CENTER FOR ELECTRICAL

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 3. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Phillips Laboratory Kirtland Air Force Base NM 87117-6008 Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base...Zindel, D.: 1963, Z. Astrophys. 57, 82. 29-13 FINAL REPORT SUMMER FACULTY RESEARCH PROGRAM AT PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific

20 CFR 664.600 - Are Local Boards required to offer summer employment opportunities in the local youth program?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Are Local Boards required to offer summer... WORKFORCE INVESTMENT ACT Summer Employment Opportunities § 664.600 Are Local Boards required to offer summer employment opportunities in the local youth program? (a) Yes, Local Boards are required to offer summer youth...

20 CFR 664.600 - Are Local Boards required to offer summer employment opportunities in the local youth program?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Are Local Boards required to offer summer... INVESTMENT ACT Summer Employment Opportunities § 664.600 Are Local Boards required to offer summer employment opportunities in the local youth program? (a) Yes, Local Boards are required to offer summer youth employment...

20 CFR 664.600 - Are Local Boards required to offer summer employment opportunities in the local youth program?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Are Local Boards required to offer summer... WORKFORCE INVESTMENT ACT Summer Employment Opportunities § 664.600 Are Local Boards required to offer summer employment opportunities in the local youth program? (a) Yes, Local Boards are required to offer summer youth...

20 CFR 664.600 - Are Local Boards required to offer summer employment opportunities in the local youth program?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Are Local Boards required to offer summer... WORKFORCE INVESTMENT ACT Summer Employment Opportunities § 664.600 Are Local Boards required to offer summer employment opportunities in the local youth program? (a) Yes, Local Boards are required to offer summer youth...

Ready for Fall? Near-Term Effects of Voluntary Summer Learning Programs on Low-Income Students' Learning Opportunities and Outcomes. RAND Summer Learning Series

ERIC Educational Resources Information Center

McCombs, Jennifer Sloan; Pane, John F.; Augustine, Catherine H.; Schwartz, Heather L.; Martorell, Paco; Zakaras, Laura

2014-01-01

Prior research has determined that low-income students lose more ground over the summer than their higher-income peers. Prior research has also shown that some summer learning programs can stem this loss, but we do not know whether large, district-run, voluntary programs can improve students' outcomes. To fill this gap, The Wallace Foundation…

How consistent are top-down hydrocarbon emissions based on formaldehyde observations from GOME-2 and OMI?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stavrakou, T.; Muller, J. F.; Bauwens, M.

2015-10-26

The vertical columns of formaldehyde (HCHO) retrieved from two satellite instruments, the Global Ozone Monitoring Instrument-2 (GOME-2) on Metop-A and the Ozone Monitoring Instrument (OMI) on Aura, are used to constrain global emissions of HCHO precursors from open fires, vegetation and human activities in the year 2010. To this end, the emissions are varied and optimized using the ad-joint model technique in the IMAGESv2 global CTM (chem-ical transport model) on a monthly basis and at the model res-olution. Given the different local overpass times of GOME- 2 (09:30 LT) and OMI (13:30 LT), the simulated diurnal cy-cle of HCHO columnsmore » is investigated and evaluated against ground-based optical measurements at seven sites in Europe, China and Africa. The modeled diurnal cycle exhibits large variability, reflecting competition between photochemistry and emission variations, with noon or early afternoon max-ima at remote locations (oceans) and in regions dominated by anthropogenic emissions, late afternoon or evening max-ima over fire scenes, and midday minima in isoprene-rich re-gions. The agreement between simulated and ground-based columns is generally better in summer (with a clear after-noon maximum at mid-latitude sites) than in winter, and the annually averaged ratio of afternoon to morning columns is slightly higher in the model (1.126) than in the ground-based measurements (1.043).The anthropogenic VOC (volatile organic compound) sources are found to be weakly constrained by the inversions on the global scale, mainly owing to their generally minor contribution to the HCHO columns, except over strongly pol-luted regions, like China. The OMI-based inversion yields total flux estimates over China close to the bottom-up inven-tory (24.6 vs. 25.5 TgVOC yr -1 in the a priori) with, how-ever, pronounced increases in the northeast of China and re-ductions in the south. Lower fluxes are estimated based on GOME-2 HCHO columns (20.6 TgVOC yr -1), in particular over the northeast, likely reflecting mismatches between the observed and the modeled diurnal cycle in this region.« less

77 FR 31724 - Exchange Visitor Program-Summer Work Travel; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-30

... DEPARTMENT OF STATE 22 CFR Part 62 RIN 1400-AD14 [Public Notice 7902] Exchange Visitor Program--Summer Work Travel; Correction AGENCY: Department of State. ACTION: Interim final rule; correction SUMMARY: This document contains minor corrections to the Exchange Visitor Program--Summer Work Travel...

7 CFR 225.1 - General purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope. This part establishes the regulations under which the Secretary will administer a Summer Food Service... nonprofit food service programs for children during the summer months and at other approved times. The...

7 CFR 225.1 - General purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope. This part establishes the regulations under which the Secretary will administer a Summer Food Service... nonprofit food service programs for children during the summer months and at other approved times. The...

7 CFR 225.1 - General purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope. This part establishes the regulations under which the Secretary will administer a Summer Food Service... nonprofit food service programs for children during the summer months and at other approved times. The...

7 CFR 225.1 - General purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope. This part establishes the regulations under which the Secretary will administer a Summer Food Service... nonprofit food service programs for children during the summer months and at other approved times. The...

Observed changes in radiographic measurements of the first ray after frontal plane rotation of the first metatarsal in a cadaveric foot model.

PubMed

Dayton, Paul; Feilmeier, Mindi; Hirschi, Jordan; Kauwe, Merrell; Kauwe, John S K

2014-01-01

We observed the changes in the angular measurements commonly used in the evaluation of the first metatarsal and first metatarsophalangeal joint in cadaveric specimens before and after frontal plane rotation of the first metatarsal. Measurements of the first and second intermetatarsal angle (IMA), hallux abductus angle, proximal articular set angle, and tibial sesamoid position (TSP) were taken after varying degrees of varus and valgus rotation of the first metatarsal. Standard dorsoplantar radiographs were taken at 0°, 10°, 20°, and 30° of valgus rotation of the first metatarsal and repeated at 10°, 20°, and 30° varus rotation of the first metatarsal. The data were analyzed using a mixed linear model to compare the change in each angle measurement over the range of valgus and varus rotation. The change in the TSP was significant in both valgus and varus rotations (p = .0004 and p = .028, respectively), an increase in valgus rotation causing an increase in the TSP and an increase in varus rotation causing a decrease in TSP. The change in the IMA was significant compared with valgus rotation (p = .028), showing that as the valgus rotation increased, the IMA also increased. However, compared with the varus rotation, the correlation was not significant (p = .18). The proximal articular set angle and hallux abductus angle measurements, compared with metatarsal rotation, showed positive trends but were not statistically significant. From our results and a review of the published data, we have hypothesized that frontal plane rotation of the first metatarsal is an integral component of hallux abducto valgus pathologic features, specifically in relation to the TSP and IMA. Copyright © 2014 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Study of adverse events following immunisation with universal and newer vaccines in the Serampore IMA Child Clinic over a period of 7 years.

PubMed

Das, Pradip Kumar

2013-04-01

Immunisation is an important part of childcare practice. It is one of the most beneficial and cost effective measures for the prevention of diseases. From the previous retrospective studies, it was evident that smallpox has been completely eradicated throughout now-a-days with the wholehearted and sincere efforts of healthcare providers by applying efficient and safe vaccine against smallpox, same is true also to polio which is now close to worldwide eradication and measles and rubella are no longer endemic in certain parts of the world. Not only has that with the introduction of safer and more efficient newer vaccines, the incidence of most other vaccine preventable disease of childhood also reduced considerably. The aim of the present study is to estimate the incidence and clinical presentation of adverse events following immunisation with universal and newer vaccines for a period of seven years using prospective active surveillance. Children under the age of 7 years were taken for universal and newer scheduled vaccinations given in the Serampore IMA Child Clinic under the supervision of the clinicians maintaining strictly the guidelines of Expanded Programme of Immunisation (Government of India). This study of adverse events following immunisation in the Serampore IMA Child Clinic confirms that the adverse events such as fever (0.37%), pain and swelling at the site of injection (0.32%0, urticarial rash (0.02%), anaphylactic shock (0.003%) are negligible. There were only two reports of anaphylaxis following preschool and infant schedule vaccines, including measles, mumps and rubella (MMR), Haemophilus influenzae type B vaccines and typhoid vaccines in approximately 52,000 infants received over a period of 7 years starting from 1st April, 2005 to 31st March, 2012 and there were no deaths or longterm effects reported during the post follow-up period in the Serampore IMA Child Clinic.

22 CFR 62.32 - Summer work travel.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Summer work travel. 62.32 Section 62.32 Foreign... Provisions § 62.32 Summer work travel. (a) Introduction. These regulations govern program participation in summer work travel programs conducted by Department of State-designated sponsors pursuant to the...

22 CFR 62.32 - Summer work travel.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Summer work travel. 62.32 Section 62.32 Foreign... Provisions § 62.32 Summer work travel. (a) Introduction. These regulations govern program participation in summer work travel programs conducted by Department of State-designated sponsors pursuant to the...

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

PubMed Central

Risacher, Shannon L.; McDonald, Brenna C.; Tallman, Eileen F.; West, John D.; Farlow, Martin R.; Unverzagt, Fredrick W.; Gao, Sujuan; Boustani, Malaz; Crane, Paul K.; Petersen, Ronald C.; Jack, Clifford R.; Jagust, William J.; Aisen, Paul S.; Weiner, Michael W.; Saykin, Andrew J.

2016-01-01

IMPORTANCE The use of anticholinergic (AC) medication is linked to cognitive impairment and an increased risk of dementia. To our knowledge, this is the first study to investigate the association between AC medication use and neuroimaging biomarkers of brain metabolism and atrophy as a proxy for understanding the underlying biology of the clinical effects of AC medications. OBJECTIVE To assess the association between AC medication use and cognition, glucose metabolism, and brain atrophy in cognitively normal older adults from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Indiana Memory and Aging Study (IMAS). DESIGN, SETTING, AND PARTICIPANTS The ADNI and IMAS are longitudinal studies with cognitive, neuroimaging, and other data collected at regular intervals in clinical and academic research settings. For the participants in the ADNI, visits are repeated 3, 6, and 12 months after the baseline visit and then annually. For the participants in the IMAS, visits are repeated every 18 months after the baseline visit (402 cognitively normal older adults in the ADNI and 49 cognitively normal older adults in the IMAS were included in the present analysis). Participants were either taking (hereafter referred to as the AC+ participants [52 from the ADNI and 8 from the IMAS]) or not taking (hereafter referred to as the AC− participants [350 from the ADNI and 41 from the IMAS]) at least 1 medication with medium or high AC activity. Data analysis for this study was performed in November 2015. MAIN OUTCOMES AND MEASURES Cognitive scores, mean fludeoxyglucose F 18 standardized uptake value ratio (participants from the ADNI only), and brain atrophy measures from structural magnetic resonance imaging were compared between AC+ participants and AC− participants after adjusting for potential confounders. The total AC burden score was calculated and was related to target measures. The association of AC use and longitudinal clinical decline (mean [SD] follow-up period, 32.1 [24.7] months [range, 6–108 months]) was examined using Cox regression. RESULTS The 52 AC+ participants (mean [SD] age, 73.3 [6.6] years) from the ADNI showed lower mean scores on Weschler Memory Scale–Revised Logical Memory Immediate Recall (raw mean scores: 13.27 for AC+ participants and 14.16 for AC− participants; P = .04) and the Trail Making Test Part B (raw mean scores: 97.85 seconds for AC+ participants and 82.61 seconds for AC− participants; P = .04) and a lower executive function composite score (raw mean scores: 0.58 for AC+ participants and 0.78 for AC− participants; P = .04) than the 350 AC− participants (mean [SD] age, 73.3 [5.8] years) from the ADNI. Reduced total cortical volume and temporal lobe cortical thickness and greater lateral ventricle and inferior lateral ventricle volumes were seen in the AC+ participants relative to the AC− participants. CONCLUSIONS AND RELEVANCE The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus, use of AC medication among older adults should likely be discouraged if alternative therapies are available. PMID:27088965

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

DOE Office of Scientific and Technical Information (OSTI.GOV)

Risacher, Shannon L.; McDonald, Brenna C.; Tallman, Eileen F.

Importance of this Paper: The use of anticholinergic (AC) medication is linked to cognitive impairment and an increased risk of dementia. To our knowledge, this is the first study to investigate the association between AC medication use and neuroimaging biomarkers of brain metabolism and atrophy as a proxy for understanding the underlying biology of the clinical effects of AC medications. Objective: To assess the association between AC medication use and cognition, glucose metabolism, and brain atrophy in cognitively normal older adults from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Indiana Memory and Aging Study (IMAS). Design, Setting, and Participants:more » The ADNI and IMAS are longitudinal studies with cognitive, neuroimaging, and other data collected at regular intervals in clinical and academic research settings. For the participants in the ADNI, visits are repeated 3, 6, and 12 months after the baseline visit and then annually. For the participants in the IMAS, visits are repeated every 18 months after the baseline visit (402 cognitively normal older adults in the ADNI and 49 cognitively normal older adults in the IMAS were included in the present analysis). Participants were either taking (hereafter referred to as the AC + participants [52 from the ADNI and 8 from the IMAS]) or not taking (hereafter referred to as the AC - participants [350 from the ADNI and 41 from the IMAS]) at least 1 medication with medium or high AC activity. Data analysis for this study was performed in November 2015. Main Outcomes and Measures: Cognitive scores, mean fludeoxyglucose F 18 standardized uptake value ratio (participants from the ADNI only), and brain atrophy measures from structural magnetic resonance imaging were compared between AC + participants and AC - participants after adjusting for potential confounders. The total AC burden score was calculated and was related to target measures. The association of AC use and longitudinal clinical decline (mean [SD] follow-up period, 32.1 [24.7] months [range, 6-108 months]) was examined using Cox regression. Results: The 52 AC + participants (mean [SD] age, 73.3 [6.6] years) from the ADNI showed lower mean scores on Weschler Memory Scale–Revised Logical Memory Immediate Recall (raw mean scores: 13.27 for AC + participants and 14.16 for AC - participants; P = .04) and the Trail Making Test Part B (raw mean scores: 97.85 seconds for AC + participants and 82.61 seconds for AC - participants; P = .04) and a lower executive function composite score (raw mean scores: 0.58 for AC + participants and 0.78 for AC - participants; P = .04) than the 350 AC - participants (mean [SD] age, 73.3 [5.8] years) from the ADNI. Reduced total cortical volume and temporal lobe cortical thickness and greater lateral ventricle and inferior lateral ventricle volumes were seen in the AC + participants relative to the AC - participants. Conclusions and Relevance of this Paper: The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus and finally, use of AC medication among older adults should likely be discouraged if alternative therapies are available.« less

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

DOE PAGES

Risacher, Shannon L.; McDonald, Brenna C.; Tallman, Eileen F.; ...

2016-04-18

Importance of this Paper: The use of anticholinergic (AC) medication is linked to cognitive impairment and an increased risk of dementia. To our knowledge, this is the first study to investigate the association between AC medication use and neuroimaging biomarkers of brain metabolism and atrophy as a proxy for understanding the underlying biology of the clinical effects of AC medications. Objective: To assess the association between AC medication use and cognition, glucose metabolism, and brain atrophy in cognitively normal older adults from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Indiana Memory and Aging Study (IMAS). Design, Setting, and Participants:more » The ADNI and IMAS are longitudinal studies with cognitive, neuroimaging, and other data collected at regular intervals in clinical and academic research settings. For the participants in the ADNI, visits are repeated 3, 6, and 12 months after the baseline visit and then annually. For the participants in the IMAS, visits are repeated every 18 months after the baseline visit (402 cognitively normal older adults in the ADNI and 49 cognitively normal older adults in the IMAS were included in the present analysis). Participants were either taking (hereafter referred to as the AC + participants [52 from the ADNI and 8 from the IMAS]) or not taking (hereafter referred to as the AC - participants [350 from the ADNI and 41 from the IMAS]) at least 1 medication with medium or high AC activity. Data analysis for this study was performed in November 2015. Main Outcomes and Measures: Cognitive scores, mean fludeoxyglucose F 18 standardized uptake value ratio (participants from the ADNI only), and brain atrophy measures from structural magnetic resonance imaging were compared between AC + participants and AC - participants after adjusting for potential confounders. The total AC burden score was calculated and was related to target measures. The association of AC use and longitudinal clinical decline (mean [SD] follow-up period, 32.1 [24.7] months [range, 6-108 months]) was examined using Cox regression. Results: The 52 AC + participants (mean [SD] age, 73.3 [6.6] years) from the ADNI showed lower mean scores on Weschler Memory Scale–Revised Logical Memory Immediate Recall (raw mean scores: 13.27 for AC + participants and 14.16 for AC - participants; P = .04) and the Trail Making Test Part B (raw mean scores: 97.85 seconds for AC + participants and 82.61 seconds for AC - participants; P = .04) and a lower executive function composite score (raw mean scores: 0.58 for AC + participants and 0.78 for AC - participants; P = .04) than the 350 AC - participants (mean [SD] age, 73.3 [5.8] years) from the ADNI. Reduced total cortical volume and temporal lobe cortical thickness and greater lateral ventricle and inferior lateral ventricle volumes were seen in the AC + participants relative to the AC - participants. Conclusions and Relevance of this Paper: The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus and finally, use of AC medication among older adults should likely be discouraged if alternative therapies are available.« less

78 FR 12031 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

... number. Food and Nutrition Service Title: 7 CFR Part 225, Summer Food Service Program. OMB Control Number.... 1761, authorizes the Summer Food Service Program (SFSP). The SFSP provides assistance to States to initiate and maintain nonprofit food service programs for needy children during the summer months and at...

Upcoming Summer Programs for Students and Staff | Poster

Cancer.gov

By Robin Meckley, Contributing Writer This summer, the Scientific Library is hosting three programs for students and NCI at Frederick staff: the Summer Video Series, Mini Science Film & Discussion Series, and Eighth Annual Student Science Jeopardy Tournament. Complete information on the programs is available on the Scientific Library’s website.

Developmental Summer Bridge Programs. What Works Clearinghouse™ Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2015

2015-01-01

Developmental summer bridge programs are designed to reduce the need for developmental education in college by providing students with accelerated instruction in areas where additional knowledge and skills are needed to help them succeed in higher education. The WWC identified one study of developmental summer bridge programs that meets WWC…

Summer Bridge Programs. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2016

2016-01-01

"Summer bridge programs" are designed to ease the transition to college and support postsecondary success by providing students with the academic skills and social resources needed to succeed in a college environment. These programs occur in the summer "bridge" period between high school and college. Although the content of…

Study of the 1978 Summer STEP. The Summer "Bridge" Program at the Learning Skills Center, University of California, Davis.

ERIC Educational Resources Information Center

Suhr, Jeanne

The summer "bridge" part of the Special Transitional Enrichment Program (STEP) at the University of California (UC), Davis, was evaluated with attention to first-year academic performance and retention. STEP, part of the Educational Opportunity Program (EOP), is an orientation and academic program to help low-income and minority students…

USAF Summer Research Program - 1994 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Group at the Phillips Laboratory at Kirtland Air Force Base...for Summer Graduate Student Research Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base, DC...2390 S. York Street Denver, CO 80208-0177 Final Report for: Summer Faculty Research Program Phillips Laboratory Sponsored by: Air Force

The Complete Resource Guide for Summer Youth Programs. Program Ideas for Summer Youth Jobs Project Managers.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This guide consists of suggestions, ideas, and tips intended to stimulate development of cooperative summer youth employment programs in local communities. Addressed in the individual sections of the guide are the following topics: tips on where to start, suggestions on how to get started, hints on securing resources, program resources, use of…

Bridging the Gap: An Impact Study of Eight Developmental Summer Bridge Programs in Texas. NCPR Brief

ERIC Educational Resources Information Center

Barnett, Elisabeth A.; Bork, Rachel Hare; Mayer, Alexander K.; Pretlow, Joshua; Wathington, Heather D.; Weiss, Madeline Joy

2012-01-01

Across the country, a growing number of recent high school graduates are participating in summer bridge programs. These programs provide accelerated and focused learning opportunities in order to help students acquire the knowledge and skills needed for college success. The state of Texas has given particular attention to summer programs as a way…

Is an Early Start the Best Start?: Evaluating the Effectiveness of a Political Science Summer Bridge Program

ERIC Educational Resources Information Center

Woodall, Gina Serignese; Herrera, Richard; Thompson, Joshua R.; Ortega, Jorge Coss

2017-01-01

Summer bridge programs are supposed to connect a graduating high school senior's summer to their first semester in college, easing the transition away from home and into a university setting. Although research is plentiful on the programs, assessments regarding the overall effectiveness of such programs have been mixed (e.g., Cabrera, Miner, and…

The Impact of a Three-Week Summer Reading Program on Students' Oral Reading Fluency

ERIC Educational Resources Information Center

Juilfs, Kelly

2014-01-01

The impacts of a summer reading program on students' reading fluency were assessed. Fifteen students in grades first through seventh voluntarily attended a nine-day summer reading program. Participants who attended the program were a good representation of the other students in the school. The school was selected due to the high percentage of…

Evaluating Summer School Programs and the Effect on Student Achievement: The Correlation between Stanford-10 Standardized Test Scores and Two Different Summer Programs

ERIC Educational Resources Information Center

Koop, Brian J.

2010-01-01

School districts looking for ways to minimize summer learning loss have implemented a variety of programs to combat this problem. Since No Child Left Behind and the need for school districts to meet the goals of Adequate Yearly Progress, it is no longer enough to limit summer learning loss. Now school leaders find it necessary to use the summer…

Safe and Secure Virtualization: Answers for IMA next Generation and Beyond

NASA Astrophysics Data System (ADS)

Almeida, Jose; Vatrinet, Francis

2010-08-01

This paper presents some of the challenges the aerospace industry is facing for the future and explains why and how a safe and secured virtualization technology can help solving these challenges Efforts around the next generation of IMA have already started, like the European FP7 funded project SCARLETT or the IDEE5 project and many avionics players and working groupware focused on how the new technologies like SMP capabilities introduced in latest CPU architectures, can help increasing system performances in future avionics system. We present PikeOS, a separation micro-kernel, which applies the state-of-the-art techniques and widely recognized standards such as ARINC 653 and MILS in order to guarantee safety and security properties, and still improve overall performance.

Microballoon Occlusion Test to Predict Colonic Ischemia After Transcatheter Embolization of a Ruptured Aneurysm of the Middle Colic Artery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tajima, Tsuyoshi, E-mail: ttajima@med.kyushu-u.ac.jp; Yoshimitsu, Kengo; Inokuchi, Hiroyuki

2008-07-15

A 76-year-old woman presented with sudden massive melena, and superior mesenteric arteriography showed an aneurysm in the middle colic artery (MCA). Because she had a history of right hemicolectomy and ligation of the inferior mesenteric artery (IMA) during open abdominal aortic aneurysm repair, embolization of the MCA aneurysm was considered to pose a risk comparable to that of colonic ischemia. A microballoon occlusion test during occlusion of the MCA confirmed retrograde visualization of the IMA branches through the collateral arteries by way of the left internal iliac artery, and embolization was successfully performed using microcoils. No colonic ischemia or aneurysmmore » rupture occurred after embolization.« less

Environmental Impact Analysis Process. Deployment Area Selection and Land Withdrawal/Acquisition DEIS. Chapter IV. Part III. Environmental Consequences to the Study Regions and Operating Base Vicinities.

DTIC Science & Technology

1980-12-01

4.4.2-4 Distribution of the larger playa lakes in the Texas high plains. 4-793 4.4.2-5 Distribution of elk in the vicinity of Beryl, Utah, OB. 4-796 4.4.2... lIMA 28DAA SUITABILITY AREAS * 221 Ci~)HYDROLOGIC SUBUNITS 08 SUITABILITY AREAS (2 ARIONA In 22M 2211 212 / 3222-D Table 4.3.2.10-1. Summary of energy...is constructed 4-636 W F’ 130 --- *47 In- IGIA 744 711 soo LPL IS12 13 0 Um ?S ______________ 119 47 lIMA 14PROVO 13 UTN4 SEVE -. 4 t UT "SA 2111 06

Tsunami Summer! 2003 Young Adult Summer Library Program.

ERIC Educational Resources Information Center

Alabama Public Library Service, Montgomery.

This manual is designed to assist public libraries in Alabama with setting up "Tsunami Summer!," a summer program for young adults, i.e., students in grades 6 through 12. The manual contains the following sections: (1) Publicity and Promotion; (2) Working with Schools; (3) Involving the Students, including teen volunteers, teen advisory…

Effects of Summer Academic Programs in Middle School on High School Test Scores, Course-Taking, and College Major

ERIC Educational Resources Information Center

Li, Yan; Alfeld, Corinne; Kennedy, Rebecca Prince; Putallaz, Martha

2009-01-01

Through their participation in a seventh-grade talent search in 1996-1997, students qualified to attend a summer program at Duke University's Talent Identification Program (Duke TIP). of the North Carolina students in this group, some attended at least one summer program in middle school and others had qualified for but did not attend a summer…

Ingredients of a Successful Summer Learning Program: A Case Study of the Building Educated Leaders for Life (BELL) Accelerated Learning Summer Program

ERIC Educational Resources Information Center

Capizzano, Jeffrey; Bischoff, Kendra; Woodroffe, Nicola; Chaplin, Duncan

2007-01-01

Based on positive results from a previous evaluation of a summer learning intervention, the current report describes the specific elements of the successful program so it can be replicated, and investigates potential barriers to implementation and replication. The study estimated impacts of the program overall; the authors could not identify which…

New Opportunities: A Status Report on the Summer Food Service Program for Children.

ERIC Educational Resources Information Center

Food Research and Action Center, Washington, DC.

During the school year, the School Lunch Program provides one-third to one-half of the nutrients low-income children consume every day. However, the rate of participation by eligible children in the Summer Food Service Program is only 15.5 percent of the target population. Created by Congress in 1968, the Summer Food Service Program is designed to…

EVALUATION OF 1966 EOA SECONDARY SUMMER SCHOOL PROGRAM. RESEARCH REPORT.

ERIC Educational Resources Information Center

GODON, ROLF M.

PRESENTED IS AN EVALUATION OF A 6-WEEK SUMMER SCHOOL PROGRAM FOR 502 DISADVANTAGED STUDENTS ENTERING JUNIOR HIGH SCHOOLS IN THE FALL OF 1966. PROGRAM GOALS WERE TO RAISE ACHIEVEMENT LEVELS, REDUCE SUMMER LEARNING LOSSES, ENCOURAGE ASPIRATION AND MOTIVATION FOR LEARNING, AND PROVIDE ENRICHMENT. THESE OBJECTIVES WERE IMPLEMENTED BY INTENSIVE…

Hats Off to Kids! Wisconsin Summer Library Program Manual, 1984. Bulletin No. 4225.

ERIC Educational Resources Information Center

Kennelly, Patti, Ed.

This guide offers suggestions for in-library, community, and school program promotion and activities, including specific ideas for the 1984 theme, "Hats Off to Children." It is intended for libraries participating in the Wisconsin Summer Library Program, which promotes summer use of the library by children, familiarizes them with public…

76 FR 68808 - Exchange Visitor Program-Cap on Current Participant Levels and Moratorium on New Sponsor...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-07

... Levels and Moratorium on New Sponsor Applications for Summer Work Travel Program AGENCY: Department of State. ACTION: Notice Regarding the Summer Work Travel Program. SUMMARY: Effective January 1, 2012, the... moratorium on designation of new Summer Work Travel sponsor organizations. FOR FURTHER INFORMATION CONTACT...

Manual for a Summer Reading Program.

ERIC Educational Resources Information Center

Medina, Sue O.

This manual provides suggestions for materials and projects to carry out a summer reading program for children based on a monster theme. The planning process outlined may be used as a "how-to" guide for developing summer reading programs on other themes as well. In addition to general guidelines, the manual provides information on the following…

Communities Can Work Together to Strengthen Summer Learning for Youth

ERIC Educational Resources Information Center

Willse, Katie

2015-01-01

High-quality summer learning programs in a given city are often only able to address a fraction of the need. Lack of access to program data and absence of stakeholder coordination compounds the problem. Working together to systematically increase program quality and provide more high-quality summer learning opportunities where families need them…

Read Hard, Play Later: Putting Summer Reading into Action.

ERIC Educational Resources Information Center

Wemett, Lisa C.; Bolan, Kimberly

1998-01-01

Provides an overview of "Read on the Wild Side," a summer reading program for young adults established by the Webster (New York) Public Library, and "Read Hard, Play Later," a young adult summer reading program of the Pioneer Library System (New York). Highlights include reading logs, T-shirts, publicity, program evaluation,…

Summer Education Program for Neurologically and Physically Handicapped Children. Summer 1975. Evaluation Report.

ERIC Educational Resources Information Center

Ellis, Ronald S.

Evaluated was the Summer Education Program for Neurologically and Physically Handicapped Children, designed to improve the performance of 145 children (6-16 years old) in the following areas--gross motor skills, swimming, fine motor skills, socialization with nonhandicapped peers, and independent daily living skills. The program included the…

Summer of Seasons Workshop Program for Emerging Educators in Earth System Science

NASA Technical Reports Server (NTRS)

Chaudhury, S. Raj

2002-01-01

Norfolk State University BEST Lab successfully hosted three Summer of Seasons programs from 1998-2001. The Summer of Seasons program combined activities during the summer with additional seminars and workshops to provide broad outreach in the number of students and teachers who participated. Lessons learned from the each of the first two years of this project were incorporated into the design of the final year's activities. The "Summer of Seasons" workshop program provided emerging educators with the familiarity and knowledge to utilize in the classroom curriculum materials developed through NASA sponsorship on Earth System Science. A special emphasis was placed on the use of advanced technologies to dispel the commonly held misconceptions regarding seasonal, climactic and global change phenomena.

Summer programming in rural communities: unique challenges.

PubMed

Phillips, Ruthellen; Harper, Stacey; Gamble, Susan

2007-01-01

During the past several decades, child poverty rates have been higher in rural than in urban areas, and now 2.5 million children live in deep poverty in rural America. Studies indicate that poor children are most affected by the typical "summer slide." Summer programming has the ability to address the issues of academic loss, nutritional loss, and the lack of safe and constructive enrichment activities. However, poor rural communities face three major challenges in implementing summer programming: community resources, human capital, and accessibility. The success of Energy Express, a statewide award-winning six-week summer reading and nutrition program in West Virginia, documents strategies for overcoming the challenges faced by poor, rural communities in providing summer programs. Energy Express (1) uses community collaboration to augment resources and develop community ownership, (2) builds human capital and reverses the acknowledged brain drain by engaging college students and community volunteers in meaningful service, and (3) increases accessibility through creative transportation strategies. West Virginia University Extension Service, the outreach arm of the land-grant institution, partners with AmeriCorps, a national service program, and various state and local agencies and organizations to implement a program that produces robust results.

The Summer Feeding Program: How to Feed the Children and Stop Program Abuses. Report to the Committee on Education and Labor, House of Representatives, by the Comptroller General of the United States.

ERIC Educational Resources Information Center

Comptroller General of the U.S., Washington, DC.

The summer food service program for children, authorized by the National School Lunch Act is one of several childfeeding programs which the Congress authorized to safeguard the health and well-being of the nation's children. Serious abuses, criminal as well as administrative, have occurred in the summer feeding program. Most have involved private…

Phun Physics 4 Phemales: Physics Camp for High School Girls

NASA Astrophysics Data System (ADS)

Kwon, Chuhee; Gu, Jiyeong; Henriquez, Laura

2014-03-01

The department of Physics and Astronomy with the department of Science Education at California State University, Long Beach hosted summer program of ``Phun Physics 4 Phemales (PP4P)'' during summer 2012 and summer 2013 with the support from APS public outreach program. PP4P summer camp was hosted along with a two-week summer science camp, Young Scientists Camp, which has been institutionalized for the last 14 years since 1999. More than 2,500 3rd -8th grade students and 250 teachers have participated in the program. PP4P program provided the tools and support that female high school students need to pursue careers in physics and/or science, technology, engineering and math (STEM) field. This girls-only camp created connections among the girls and built confidence. In addition PP4P program introduced students to key principles in physics by a hands-on lab environment and demonstrated the real-world social impact of physics. In summer 2012, high school girls worked on physics experimental project on electronics and in summer 2013 they worked on the mechanics. I would share our experience in this program and the impact on the female high school students. This work was supported by 2012 Public Outreach and Informing the Public Grants from American Physical Society.

Summer Program Aims to Improve Literacy Skills of Black Male Teens

ERIC Educational Resources Information Center

West, Cassandra

2012-01-01

In this article, the author talks about a summer program at the African American Adolescent Male Summer Literacy Institute which aims to improve literacy skills of black male teens. The African American Adolescent Male Summer Literacy Institute is now in its fourth year at the University of Illinois-Chicago (UIC). Alfred Tatum, director of the…

Summer Boost: Challenges and Opportunities in Summer Programs for Rising Kindergarten Students

ERIC Educational Resources Information Center

Condliffe, Barbara; Foster, Anna; Jacob, Robin

2017-01-01

There is a growing belief that access to academic opportunities during the summer can help close the achievement gap between low-income students and their higher-income peers. But while significant research is emerging on summer programs for school-age children, information on the preschool period is limited. The Expanding Children's Early…

PVAMU/XULA/BCM Summer Prostate Cancer Research Program

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-15-1-0677 TITLE: PVAMU/XULA/BCM Summer Prostate Cancer Research Program PRINCIPAL INVESTIGATOR: Nancy L. Weigel...Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for Public Release; Distribution Unlimited...PVAMU/XULA/BCM Summer Prostate Cancer Research Program 5b. GRANT NUMBER W81XWH-15-1-0677 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Nancy L. Weigel

Effectiveness of Geosciences Exploration Summer Program (GeoX) for Increasing Awareness and Knowledge of Geosciences

ERIC Educational Resources Information Center

Houser, Chris; Garcia, Sonia; Torres, Janet

2015-01-01

Summer research experiences are an increasingly popular means of increasing awareness of, and developing interest in, the geosciences and other science, technology, engineering, and math programs. We describe and report the preliminary results of a 1-wk Geosciences Exploration Summer Program in the College of Geosciences at Texas A&M…

An Assessment of Teacher Education Students' Perceptions and Satisfaction of Their Learning Experiences in a Summer Pilot Program

ERIC Educational Resources Information Center

Hicks, Terence; Lewis, Leontye; Munn, Geraldine; Jordon, Earlyn; Charles, Kelly

2010-01-01

This study assessed teacher education students' perceptions and satisfaction of their learning experiences concerning an accelerated summer pilot program. In addition, the study provided information on the impact and teaching effectiveness of the accelerated teacher education summer pilot program on participating students. Results from this study…

Summer Food Service Program. Nourishing News. Volume 3, Issue 8

ERIC Educational Resources Information Center

Idaho State Department of Education, 2009

2009-01-01

The primary goal of the Summer Food Service Program (SFSP) is to provide nutritious meals to children in low-income areas when school is not in session. This issue of "Nourishing News" focuses on SFSPs. The articles contained in this issue are: (1) Is Your Summer Food Program Financially Fit? (Jean Zaske); (2) Keeping the…

The Baltimore City Schools Middle School STEM Summer Program with VEX Robotics

ERIC Educational Resources Information Center

Mac Iver, Martha Abele; Mac Iver, Douglas J.

2015-01-01

In 2011 Baltimore City Schools submitted a successful proposal for an Investing in Innovations (i3) grant to offer a three year (2012-2014) summer program designed to expose rising sixth through eighth grade students to VEX robotics. The i3-funded Middle School Science, Technology, Engineering and Mathematics (STEM) Summer Learning Program was…

A High School Intensive Summer Mandarin Course: Program Model and Learner Outcomes

ERIC Educational Resources Information Center

Xu, Xiaoqiu; Padilla, Amado M.; Silva, Duarte; Masuda, Norman

2012-01-01

This article describes a STARTALK intensive summer high school Mandarin language and culture program that was conducted for three summers. Participants across the three years included 40 Mandarin Level II and 53 Mandarin Level III high school students. Quantitative and qualitative data are presented to show the effectiveness of the program.…

The Program and Treatment Effect of Summer Jobs on Girls' Post-Schooling Incomes.

PubMed

Alam, Moudud; Carling, Kenneth; Nääs, Ola

2015-06-01

Public programs offering summer jobs to smooth the transition from school to work is commonplace. However, the empirical support for summer jobs is limited. This article exploits the availability of registered individual information and random allocation to summer jobs to provide empirical evidence on this issue. To identify the effect of summer job programs on the post-schooling incomes of the intended participants. Also to identify the effect of sophomore girls' high school work experience on their post-schooling incomes. In this article, 1,447 sophomore girls from 1997 to 2003 are followed 5-12 years after graduation. They all applied to Falun municipality's (Sweden) summer job program, and about 25% of them were randomly allotted a job. The random allocation to a summer job is used to identify the causal effect of sophomore girls' high school income on their post-schooling incomes. All the 1,447 sophomore girls who applied to Falun municipality's summer job program during 1997-2003. Annual post-schooling income is used as an outcome measure. The work experience of girls in high school is also measured in terms of total income while in high school. The program led to a substantially larger accumulation of income during high school as well as 19% higher post-schooling incomes. The high school income led to a post-schooling income elasticity of 0.37 which is, however, potentially heterogeneous with regard to academic ability. Both the program effect and the causal effect of high school income on post-schooling incomes were substantial and statistically significant. © The Author(s) 2015.

Formal Darwinism, the individual-as-maximizing-agent analogy and bet-hedging

PubMed Central

Grafen, A.

1999-01-01

The central argument of The origin of species was that mechanical processes (inheritance of features and the differential reproduction they cause) can give rise to the appearance of design. The 'mechanical processes' are now mathematically represented by the dynamic systems of population genetics, and the appearance of design by optimization and game theory in which the individual plays the part of the maximizing agent. Establishing a precise individual-as-maximizing-agent (IMA) analogy for a population-genetics system justifies optimization approaches, and so provides a modern formal representation of the core of Darwinism. It is a hitherto unnoticed implication of recent population-genetics models that, contrary to a decades-long consensus, an IMA analogy can be found in models with stochastic environments (subject to a convexity assumption), in which individuals maximize expected reproductive value. The key is that the total reproductive value of a species must be considered as constant, so therefore reproductive value should always be calculated in relative terms. This result removes a major obstacle from the theoretical challenge to find a unifying framework which establishes the IMA analogy for all of Darwinian biology, including as special cases inclusive fitness, evolutionarily stable strategies, evolutionary life-history theory, age-structured models and sex ratio theory. This would provide a formal, mathematical justification of fruitful and widespread but 'intentional' terms in evolutionary biology, such as 'selfish', 'altruism' and 'conflict'.

Prospective multicentre study in intensive care units in five cities from the Kingdom of Saudi Arabia: Impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on rates of central line-associated bloodstream infection.

PubMed

Al-Abdely, Hail M; Alshehri, Areej Dhafer; Rosenthal, Victor Daniel; Mohammed, Yassir Khidir; Banjar, Weam; Orellano, Pablo Wenceslao; Assiri, Abdullah Mufareh; Kader, Nahla Moustafa Abedel; Enizy, Hessa Abdullah Al; Mohammed, Diaa Abdullah; Al-Awadi, Duaa Khalil; Cabato, Analen Fabros; Wasbourne, Maria; Saliya, Randa; Aromin, Rosita Gasmin; Ubalde, Evangelina Balon; Diab, Hanan Hanafy; Alkamaly, Modhi Abdullah; Alanazi, Nawal Mohammed; Hassan Assiry, Ibtesam Yahia; Molano, Apsia Musa; Flores Baldonado, Celia; Al-Azhary, Mohamed; Al Atawi, Sharifa; Molano, Apsia Musa; Al Adwani, Fatima Mohammad; Casuyon Pahilanga, Arlu Marie; Nakhla, Raslan; Al Adwani, Fatma Mohammad; Nair, Deepa Sasithran; Sindayen, Grace; Malificio, Annalyn Amor; Helali, Najla Jameel; Al Dossari, Haya Barjas; Kelany, Ashraf; Algethami, Abdulmajid Ghowaizi; Yanne, Leigh; Tan, Avigail; Babu, Sheema; Abduljabbar, Shatha Mohammad; Bukhari, Syed Zahid; Basri, Roaa Hasan; Mushtaq, Jeyashri Jaji; Rushdi, Hala; Turkistani, Abdullah Abdulaziz; Gonzales Celiz, Jerlie Mae; Al Raey, Mohammed Abdullah; Al-Zaydani Asiri, Ibrahim Am; Aldarani, Saeed Ali; Laungayan Cortez, Elizabeth; Demaisip, Nadia Lynette; Aziz, Misbah Rehman; Omer Abdul Aziz, Ali; Al Manea, Batool; Samy, Eslam; Al-Dalaton, Mervat; Alaliany, Mohammed Jkedeb

2017-01-01

To analyse the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and INICC Surveillance Online System (ISOS) on central line-associated bloodstream infection (CLABSI) rates in five intensive care units (ICUs) from October 2013 to September 2015. Prospective, before-after surveillance study of 3769 patients hospitalised in four adult ICUs and one paediatric ICU in five hospitals in five cities. During baseline, we performed outcome and process surveillance of CLABSI applying CDC/NHSN definitions. During intervention, we implemented IMA and ISOS, which included: (1) a bundle of infection prevention practice interventions; (2) education; (3) outcome surveillance; (4) process surveillance; (5) feedback on CLABSI rates and consequences; and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed. During baseline, 4468 central line (CL) days and 31 CLABSIs were recorded, accounting for 6.9 CLABSIs per 1000 CL-days. During intervention, 12,027 CL-days and 37 CLABSIs were recorded, accounting for 3.1 CLABSIs per 1000 CL-days. The CLABSI rate was reduced by 56% (incidence-density rate, 0.44; 95% confidence interval, 0.28-0.72; P = 0.001). Implementing IMA through ISOS was associated with a significant reduction in the CLABSI rate in the ICUs of Saudi Arabia.

Medical ozone therapy reduces oxidative stress and testicular damage in an experimental model of testicular torsion in rats.

PubMed

Tusat, Mustafa; Mentese, Ahmet; Demir, Selim; Alver, Ahmet; Imamoglu, Mustafa

2017-01-01

Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate the effect of ozone therapy on testicular damage due to I/R injury in an experimental torsion model. 24 male Sprague-Dawley rats were divided into 3 groups; sham-operated, torsion/detorsion (T/D), and T/D+ozone. Ozone (1mg/kg) was injected intraperi-toneally 120 minutes before detorsion and for the following 24h. Blood and tissue samples were collected at the end of 24h. Johnsen score, ischemia modified albumin (IMA), total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) levels were determined. Levels of IMA, TOS, OSI, and histopathological scores increased in the serum/tissue of the rats in the experimental T/D group. Serum IMA, TOS, and OSI levels and tissue histo-pathological scores were lower in the rats treated with ozone compared with the T/D group. Our study results suggest that ozone therapy may exhibit beneficial effects on both biochemical and histopathological findings. Clinical trials are now necessary to confirm this. Copyright® by the International Brazilian Journal of Urology.

Elimination of sucrose transport and hydrolysis in Saccharomyces cerevisiae: a platform strain for engineering sucrose metabolism

PubMed Central

Marques, Wesley Leoricy; Mans, Robert; Marella, Eko Roy; Cordeiro, Rosa Lorizolla; van den Broek, Marcel; Daran, Jean-Marc G.; Pronk, Jack T.; Gombert, Andreas K.; van Maris, Antonius J.A.

2017-01-01

Abstract Many relevant options to improve efficacy and kinetics of sucrose metabolism in Saccharomyces cerevisiae and, thereby, the economics of sucrose-based processes remain to be investigated. An essential first step is to identify all native sucrose-hydrolysing enzymes and sucrose transporters in this yeast, including those that can be activated by suppressor mutations in sucrose-negative strains. A strain in which all known sucrose-transporter genes (MAL11, MAL21, MAL31, MPH2, MPH3) were deleted did not grow on sucrose after 2 months of incubation. In contrast, a strain with deletions in genes encoding sucrose-hydrolysing enzymes (SUC2, MAL12, MAL22, MAL32) still grew on sucrose. Its specific growth rate increased from 0.08 to 0.25 h−1 after sequential batch cultivation. This increase was accompanied by a 3-fold increase of in vitro sucrose-hydrolysis and isomaltase activities, as well as by a 3- to 5-fold upregulation of the isomaltase-encoding genes IMA1 and IMA5. One-step Cas9-mediated deletion of all isomaltase-encoding genes (IMA1-5) completely abolished sucrose hydrolysis. Even after 2 months of incubation, the resulting strain did not grow on sucrose. This sucrose-negative strain can be used as a platform to test metabolic engineering strategies and for fundamental studies into sucrose hydrolysis or transport. PMID:28087672

Supplemental Summer Literacy Instruction: Implications for Preventing Summer Reading Loss

ERIC Educational Resources Information Center

McDaniel, Sara C.; McLeod, Ragan; Carter, Coddy L.; Robinson, Cecil

2017-01-01

Summer reading loss is a prevalent problem that occurs primarily for students who are not exposed to or encouraged to read at home or in summer programs when school is out. This problem prevails among early readers from low-income backgrounds. This study provided 31 six and seven-year-old children with a structured guided reading program through…

Preventing Summer Learning Loss: Results of a Summer Literacy Program for Students from Low-SES Homes

ERIC Educational Resources Information Center

Bowers, Lisa M.; Schwarz, Ilsa

2018-01-01

Among the academic challenges faced by students from low-socioeconomic status (SES) homes is the loss of academic skills during the summer months. A total of 22 elementary students from low-SES homes participated in a summer program designed to improve oral and written narrative skills. We gathered oral and written narrative samples at the…

20 CFR 632.260 - Worksite standards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.260 Worksite standards... rules and regulations governig the summer program. (2) Such written agreements may be memoranda of...

20 CFR 632.260 - Worksite standards.

Code of Federal Regulations, 2011 CFR

2011-04-01

... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.260 Worksite standards... rules and regulations governig the summer program. (2) Such written agreements may be memoranda of...

20 CFR 632.260 - Worksite standards.

Code of Federal Regulations, 2012 CFR

2012-04-01

... EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.260 Worksite standards... rules and regulations governig the summer program. (2) Such written agreements may be memoranda of...

Summer outdoor programs: their participants and their effects

Treesearch

Rachel Kaplan

1977-01-01

In a study of the benefits of various summer programs, especially those involving wilderness experiences, the use of pretests for all the groups made possible evaluation of the degree of self-selection as well. Similar tests 6 months later showed the influences of the summer programs themselves. The results suggest that even a relatively short encounter with the out-of...

Determining the Impact of a Summer Bridge Program on Academic Success for First-Year College Students

ERIC Educational Resources Information Center

Medina, Mary Christine

2016-01-01

The purpose of this study was to determine the impact of a summer bridge program geared toward first-year students at a large public university located in the Southeastern United States. The research question guiding this study was, "Does participation in a summer bridge program increase academic success for first-year college students?"…

North Carolina's Summer School Program for High-Risk Students: A Two-Year Follow-Up of Student Achievement.

ERIC Educational Resources Information Center

Ward, Martha Szegda

The long-term effectiveness of the North Carolina Basic Education Summer School Program (BEP) was examined. North Carolina has instituted a testing and summer remediation program for academically at-risk students at grades 3, 6, and 8. The BEP sample was obtained by a stratified random sampling of schools in North Carolina. Results were…

A Summative Evaluation of a Middle School Summer Math Program

ERIC Educational Resources Information Center

Nelson, Brian W.

2014-01-01

By some estimates, students lose an average of 2.6 months of learning during summer break, roughly one quarter of the time spent in school. To combat this problem, the school under study implemented a summer math program that was thematically linked to the Boston Red Sox baseball team. Hundreds of students have participated in the program, but the…

Musculoskeletal and neurological complications following coronary artery bypass graft surgery: A comparison between saphenous vein and internal mammary artery grafting.

PubMed

El-Ansary, Doa; Adams, Roger; Ghandi, Ajay

2000-01-01

The internal (thoracic) mammary artery (IMA) is currently the vessel of choice for coronary artery bypass grafting (CABG), due to its long term patency. The purpose of this study was to compare the incidence and nature of musculoskeletal and neurological complications following saphenous vein grafting (SVG) and internal mammary artery grafting (IMAG). Ninety-seven patients were screened by a physiotherapist for musculoskeletal and neurological complications three to six weeks following cardiac surgery. The incidence of new musculoskeletal and neurological complications was significantly higher in patients following IMAG (78.5 per cent) than SVG (45 per cent) (p < 0.001, chi2(1) = 17.04). A significant association between musculoskeletal complications affecting the anterior chest and harvesting of the IMA was also demonstrated.

Unusual arterial pattern of the gastrointestinal tract: inferior mesenteric artery arising from the iliac artery and corkscrew external iliac.

PubMed

Nassar, Lara; Atweh, Lamya Ann; Jurjus, Abdo; Al Kutoubi, Aghiad

2012-07-01

Anatomical variations of the digestive system arteries are important due to their clinical significance. However, anomalies in the inferior mesenteric artery (IMA) are the least common compared with the celiac trunk and superior mesenteric artery. This report describes the case of a 67-year-old man with an extremely rare variant in which the IMA arises from the left common iliac artery, and the ipsilateral external iliac artery has a corkscrew pattern. These findings were depicted during computed tomography angiography of the abdomen and pelvis. This case is the first report of such a variation associated with a left external iliac artery turning into a double loop before forming the femoral artery. The embryological and clinical significance of such an anomaly are discussed.

Social and Economic Change in Southern Africa. Fulbright-Hays Summer Seminars Abroad Program, Summer 1991. [Curriculum Projects and Papers.

ERIC Educational Resources Information Center

Institute of International Education, New York, NY.

This document presents curriculum projects and papers written by U.S. teachers who traveled to countries in Southern Africa in the summer of 1991 as part of the Fulbright-Hays Summer Seminars Abroad Program. The included projects and papers are: "Through a Glass Darkly: The Enigmatic Educational System of Botswana" (Alan C. Howard);…

Parker Migrant Summer Story. A Report from Parker Summer School Migrant Program: Kindergarten Through Grade Six.

ERIC Educational Resources Information Center

Pollard, Merel E., Comp.

Before the beginning of the summer school, a workshop was held for the teachers and aides to present ways to: (1) make migrant and American Indian children more aware of their heritage and (2) help them become more familiar with career possibilities. Objectives of the summer program were: (1) career exploration; (2) cultural enrichment (i.e., art,…

What Is a Summer Job Worth? The Impact of Summer Youth Employment on Academic Outcomes

ERIC Educational Resources Information Center

Leos-Urbel, Jacob

2014-01-01

This paper estimates the impact of New York City's Summer Youth Employment Program (SYEP) on school attendance and other educational outcomes in the following school year for a large sample of low-income high school students. The program provides summer jobs and training to youth aged 14 to 21, and due to high demand allocates slots through a…

Scarf versus chevron osteotomy for the correction of 1-2 intermetatarsal angle in hallux valgus: a systematic review and meta-analysis.

PubMed

Smith, Simon E; Landorf, Karl B; Butterworth, Paul A; Menz, Hylton B

2012-01-01

The chevron and scarf osteotomies are commonly used for the surgical management of hallux valgus (HV). However, there is debate as to whether one osteotomy provides more 1-2 intermetatarsal (1-2 IMA) correction than the other. The objective of this systematic review and meta-analysis was to compare the effectiveness of 3 types of first metatarsal osteotomy for reducing the 1-2 IMA in HV correction: the chevron osteotomy, the long plantar arm (modified) chevron osteotomy, and the scarf osteotomy. A systematic search for eligible studies was performed of the following databases: Medline, Embase (Ovid), CINAHL (EBSCO Host), and The Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Clinical Trials. Only English-language studies previous to May 2010 were included in the review. Additional hand and electronic content searches of relevant foot and orthopaedic journals were performed. Criteria for inclusion in this analysis included systematic reviews of randomized controlled trials, prospective and retrospective cohort studies, and case-control studies, as well as case-series studies involving the chevron, scarf, or long plantar arm chevron osteotomy of >20 participants with a minimum of 80% follow-up. Quality of evidence of the included studies was assessed with the Grading of Recommendations Assessment, Development and Evaluation system. All pooled analyses were based on a fixed effects model. There was a total of 1351 participants who underwent either a chevron (n = 1028), scarf (n = 300), or long plantar arm chevron osteotomy (n = 23). Only one study for the long plantar arm chevron group fitted the eligibility criteria for this review; however, it was not amenable to meta-analysis. The chevron osteotomy was associated with a mean reduction of 1-2 IMA from preoperative to postoperative of 5.33° (95% confidence interval, 5.12 to 5.54, p < .001), and the scarf osteotomy was associated with a mean reduction of 6.21° (95% confidence interval, 5.70 to 6.72, p < .001). There was a statistically significant 0.88° increase in the correction of the 1-2 IMA in favor of the scarf osteotomy compared with the chevron osteotomy. The studies included in this review were of very low- to low-quality evidence. Our findings indicate that the scarf osteotomy provides greater correction of the 1-2 IMA when used for HV correction. However, only a weak recommendation in favor of the scarf osteotomy can be made based on the low quality of evidence of the studies included in this analysis. Copyright © 2012 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

[Application of three-dimensional printing technology to design individual angle section on Chevron of hallux valgus osteotomy].

PubMed

Zhang, Yu-Hang; Bi, Da-Wei; Chen, Yi-Min; Zu, Gang; Ma, Hai-Tao

2018-03-25

To explore clinical application of three-dimensional printing technology to design individual angle section on Chevron of hallux valgus osteotomy. From May 2013 to May 2016, 47 patients(66 feet) with mild to moderate hallux valgus treated by Chevron osteotomy according to different preoperative design were divided into computer osteotomy group(group A) and traditional osteotomy group(group B). In group A, there were 25 patients (33 feet), including 4 males(5 feet) and 21 females(28 feet) with an average age of (47.88±6.08) years old, average weight IMA was (13.58±1.15) degree, AOFAS score was 59.00±5.86, and treated individual 3D printing technology to design operation scheme. While in group B, there were 22 patients (33 feet), including 3 males (3 feet) and 19 females (28 feet) with an average age of (48.16±6.16) years old, average weight IMA was(13.51±1.14) degree, AOFAS score was 60.67±5.85, and treated with osteotomy according to surgical experience. Operation time, blood loss, hospital stays, VAS score at 1 week after operation, wound healing and improvement of postoperative weight-bearing intermetatarsal angle(IMA) were compared between two groups, AOFAS score system was used to evaluate ankle function after surgery. There was no significant difference in following-up between group A 12.41±2.32 and group B 11.73±2.76. There was 1 patient in group B were excluded. Others perform good wounds healing on the first stage after operation. There were no significant differences in operation time, blood loss, hospital stays and VAS score at 1 week after operation( P <0.05); IMA in group A was (5.21±0.88)°, (6.42±0.85)° in group B, and had significant differences between two groups ( t =5.68, P <0.05). There was obvious meaning in AOFAS score between group A 88.15±5.19 and group B 82.90±5.01( t =4.14, P <0.05). Fourteen feet in group A obtained excellent results and 19 feet good, while 5 feet in group B obtained excellent results and 27 feet good. Compared with traditional osteotomy group, three-dimensional printing technology to design individual angle section on Chevron of hallux valgus osteotomy could better correct IMA, improve postoperative foot function, and it is a kind of individualized and digital method to design operation. Copyright© 2018 by the China Journal of Orthopaedics and Traumatology Press.

Antimicrobial treatment of clinical mastitis in the eastern United States: The influence of dairy farmers' mastitis management and treatment behavior and attitudes.

PubMed

Kayitsinga, J; Schewe, R L; Contreras, G A; Erskine, R J

2017-02-01

To assess both the behaviors and social variables related to antimicrobial therapy for clinical mastitis, we sent a survey to 1,700 dairy farms in Michigan, Pennsylvania, and Florida in January and February 2013. The survey included questions related to 7 major areas: sociodemographic and farm characteristics, milking proficiency, milking systems, cow environment, infected cow monitoring and treatment, farm labor, and attitudes toward mastitis and related antimicrobial use. The overall response rate was 41% (21% in Florida, 39% in Michigan, and 45% in Pennsylvania). Herd size ranged from 9 to 5,800 cows. Only a small proportion of herds frequently or always cultured milk samples for bacteriology from cows with a high somatic cell count (17%), cows with clinical mastitis (18%), or bulk tank milk (13%). Likewise, only 56% of herds frequently or always maintained records of all treated cows and 49% reviewed records before administering mastitis treatments. Multivariate analysis determined that use of treatment records was associated with increased likelihood of frequent use for both intramammary (IMA) and systemic (SYA) administration of antimicrobial drugs for therapy of clinical mastitis. As would be expected, use of natural (organic) therapies was associated with decreased use of IMA, as was the respondent being a member of an Amish community. Lower levels of education and the use of bacterins to control Staphylococcus aureus mastitis were also associated with decreased IMA, whereas increased use of IMA at dry off and the belief that "bad luck" plays a role in mastitis problems were associated with increased IMA. Use of an internal teat sealant, the respondent being the sole proprietor, being from Michigan, use of conductivity to measure subclinical mastitis, the respondent placing increasing importance on decreasing antibiotic residues in cull cows, and having financial incentives for employees linked to somatic cell count were associated with increased use of SYA for the treatment of clinical mastitis. Use of sand or mattresses for bedding were associated with decreased SYA. These findings highlight the need to improve the acceptance of practices that are consistent with prudent antimicrobial use for the treatment of clinical mastitis on dairy farms. Additionally, the willingness of dairy farmers to administer antimicrobial drugs for the treatment of clinical mastitis is associated with other mastitis-related practices and attitudes. The Authors. Published by the Federation of Animal Science Societies and Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

Tabulations of Responses from the 2000 Survey of Reserve Component Personnel: Volume 2. Military Plans, Military Training,and Military Unit

DTIC Science & Technology

2002-08-01

19.5 17.3 19.5 27.0 17.7 19.8 21.5 26.0 (18.8,20.2) (16.0,18.7) (18.3,20.8) (25.2,28.9) (16.0,19.5) (18.4,21.2) (19.9,23.1) (24.2,27.9) 7 - 10 years...than 1 full year 1 - 4 years 5 - 6 years 7 - 10 years Reserve Program Ever Deployed Deployed Never Deployed TPU AGR/TAR/AR Military Tech IMA Reserve...precision and/or unweighted denominator size between 30 and 59. 7 - 10 years 11 - 14 years 15 - 19 years 20 - 25 years DoD None or less than 1 full year

20 CFR 632.256 - Submission of applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

20 CFR 632.256 - Submission of applications.

Code of Federal Regulations, 2012 CFR

2012-04-01

... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

All Children Deserve Uninterrupted Learning!

ERIC Educational Resources Information Center

Brown, Fred

2015-01-01

Teachers often start a new school year working extremely hard to reteach last year's content, particularly for their lower income students. According to "Making Summer Count," a report commissioned by The Wallace Foundation and written by researchers at Rand, rigorous studies of voluntary summer programs, mandatory summer programs, and…

20 CFR 632.256 - Submission of applications.

Code of Federal Regulations, 2011 CFR

2011-04-01

... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

Integrated Modular Avionics for Spacecraft: Earth Observation Use Case Demonstrator

NASA Astrophysics Data System (ADS)

Deredempt, Marie-Helene; Rossignol, Alain; Hyounet, Philippe

2013-08-01

Integrated Modular Avionics (IMA) for Space, as European Space Agency initiative, aimed to make applicable to space domain the time and space partitioning concepts and particularly the ARINC 653 standard [1][2]. Expected benefits of such an approach are development flexibility, capability to provide differential V&V for different criticality level functionalities and to integrate late or In-Orbit delivery. This development flexibility could improve software subcontracting, industrial organization and software reuse. Time and space partitioning technique facilitates integration of software functions as black boxes and integration of decentralized function such as star tracker in On Board Computer to save mass and power by limiting electronics resources. In aeronautical domain, Integrated Modular Avionics architecture is based on a network of LRU (Line Replaceable Unit) interconnected by AFDX (Avionic Full DupleX). Time and Space partitioning concept is applicable to LRU and provides independent partitions which inter communicate using ARINC 653 communication ports. Using End System (LRU component) intercommunication between LRU is managed in the same way than intercommunication between partitions in LRU. In such architecture an application developed using only communication port can be integrated in an LRU or another one without impacting the global architecture. In space domain, a redundant On Board Computer controls (ground monitoring TM) and manages the platform (ground command TC) in terms of power, solar array deployment, attitude, orbit, thermal, maintenance, failure detection and recovery isolation. In addition, Payload units and platform units such as RIU, PCDU, AOCS units (Star tracker, Reaction wheels) are considered in this architecture. Interfaces are mainly realized through MIL-STD-1553B busses and SpaceWire and this could be considered as the main constraint for IMA implementation in space domain. During the first phase of IMA SP project, ARINC653 impact was analyzed. Requirements and architecture for space domain were defined [3][4] and System Executive platforms (based on Xtratum, Pike OS, and AIR) were developed with RTEMS as Guest OS. This paper focuses on the demonstrator developed by Astrium as part of IMA SP project. This demonstrator has the objective to confirm operational software partitioning feasibility above Xtratum System Executive Platform with acceptable CPU overhead.

Prediabetes is associated with microalbuminuria, reduced kidney function and chronic kidney disease in the general population: The KORA (Cooperative Health Research in the Augsburg Region) F4-Study.

PubMed

Markus, M R P; Ittermann, T; Baumeister, S E; Huth, C; Thorand, B; Herder, C; Roden, M; Siewert-Markus, U; Rathmann, W; Koenig, W; Dörr, M; Völzke, H; Schipf, S; Meisinger, C

2018-03-01

We investigated the associations of serum fasting (FG) and 2-h postload (2HG) glucose from an oral glucose tolerance test (OGTT), glycated hemoglobin (HbA1c), fasting insulin and the homeostasis model assessment-insulin resistance index (HOMA-IR) with urinary albumin-to-creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR). We performed cross-sectional analyses of 2713 subjects (1429 women; 52.7%) without known type 2 diabetes, aged 31-82 years, from the KORA (Cooperative Health Research in the Augsburg Region) F4-Study. FG, 2HG, HbA1c, fasting insulin, HOMA-IR and glucose tolerance categories were analyzed for association with ACR and eGFR in multivariable adjusted linear and median regression models, and with isolated microalbuminuria (i-MA), isolated reduced kidney function (i-RKF) and chronic kidney disease (CKD, defined as MA and/or RKF) in multivariable adjusted logistic regression models. Among the 2713 study participants, 28% revealed prediabetes (isolated impaired fasting glucose [i-IFG], isolated glucose tolerance [i-IGT] or both by American Diabetes Association definition), 4.2% had unknown type 2 diabetes, 6.5% had i-MA, 3.1% i-RKF and 10.9% CKD. In multivariable adjusted analysis, all continuous variables (FG, 2HG, HbA1c, fasting insulin and HOMA-IR) were associated with i-MA, i-RKF and CKD. The odds ratios (ORs) for i-MA and CKD were 1.54 (95% confidence interval: 1.02-2.33) and 1.58 (1.10-2.25) for individuals with i-IFG. Moreover, the OR for i-RKF was 2.57 (1.31-5.06) for individuals with IFG + IGT. Our findings suggest that prediabetes might have harmful effects on the kidney. Copyright © 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

HBCU Summer Undergraduate Training Program in Prostate Cancer: A Partnership Between USU-CPDR and UDC

DTIC Science & Technology

2016-10-01

Award Number: W81XWH-14-2-0142 TITLE: HBCU Summer Undergraduate Training Program in Prostate Cancer : A Partnership Between USU-CPDR and UDC... Cancer : A Partnership Between USU-CPDR and UDC 5a. CONTRACT NUMBER: 5b. GRANT NUMBER: W81XWH-14-2-0142 5c. PROGRAM ELEMENT NUMBER: 6. AUTHOR(S...second year of the award (2016), 4 meritorious students were selected under HBCU Summer Undergraduate Training Program in Prostate Cancer by USU-CPDR

Summer Research Apprentice Program report. [Summer Research Apprentice Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curington, B.

1982-01-01

The Summer Research Apprentice Program is designed to provide students with their first look at college life while preparing them for possible careers in mathematics, science and engineering. The 23 students, enrolled as college freshmen for 8 hours of college credit, took courses in Trigonometry, College Algebra and introduction to Research (4 students were enrolled in Calculus 1 instead of Trigonometry and College Albebra). During this third year of operation, refinements were made in both the administration of the program and in the method of implementation.

1998 Winds of Change Guide to Summer Internships, Co-op and Minority School Programs.

ERIC Educational Resources Information Center

Winds of Change, 1998

1998-01-01

Lists internships, work experience, cooperative education, and university research programs for American-Indian and minority college students, as well as summer programs for middle school and high school students. Lists 28 programs alphabetically; entries contain a short program description, prerequisites, deadlines and requirements for…

AACJC International/Intercultural Consortium Summer Study Programs Overseas, 1979.

ERIC Educational Resources Information Center

Jacobsen, Becky

Responses are presented to a questionnaire on overseas summer programs that was sent in January 1979 to members of the American Association of Community and Junior Colleges (AACJC) International/Intercultural Consortium (IIC). Program descriptions are listed alphabetically by world region and country. Program information includes: name of program,…

75 FR 3197 - Summer Food Service Program; 2010 Reimbursement Rates

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-20

..., reimbursement has been based solely on a ``meals times rates'' calculation, without comparison to actual or... public of the annual adjustments to the reimbursement rates for meals served in the Summer Food Service... to the reimbursement rates for meals served in the Summer Food Service Program (SFSP). As required...

The 1982 NASA/ASEE summer faculty fellowship research program

NASA Technical Reports Server (NTRS)

1982-01-01

Aht NASA/ASEE Summer Faculty Fellowship Research Program conducted at the Marshall Space Flight Center by the University of Alabama at Huntsville, Ala. during the summer of 1982 is described. Abstracts of the Final Reports submitted by the Fellows detailing the results of their research are also presented.

An Interactive Analytical Chemistry Summer Camp for Middle School Girls

ERIC Educational Resources Information Center

Robbins, Mary E.; Schoenfisch, Mark H.

2005-01-01

A summer outreach program, which was implemented for the first time in the summer of 2004, that provided middle school girls with an opportunity to conduct college-level analytical chemistry experiments under the guidance of female graduate students is explained. The program proved beneficial to participants at each level.

Finding the Resources for Summer Learning Programs

ERIC Educational Resources Information Center

Sundius, M. Jane

2007-01-01

Research on summer learning losses has unambiguous implications for America: all children need learning opportunities in the summer. But how and when policymakers, educators, and youth service providers will fashion appropriate programming are far less clear. At the root of this problem is the need to vastly increase, stabilize, and coordinate…

Summer Learning Programs Yield Key Lessons for Districts and Policymakers

ERIC Educational Resources Information Center

Augustine, Catherine H.; McCombs, Jennifer Sloan

2015-01-01

The Wallace Foundation is funding a multiyear demonstration project to determine whether voluntary, district summer learning programs can stem summer learning loss for low-income students. Six districts--Boston, Cincinnati, Dallas, Duval County (Florida), Pittsburgh, and Rochester, New York--were selected for the demonstration project and…

20 CFR 628.710 - Period of program operation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... TITLE II OF THE JOB TRAINING PARTNERSHIP ACT The Summer Youth Employment and Training Program § 628.710... be conducted during the school vacation period occurring duri the summer months. (b) An SDA operating... vacation period(s) treated as the period(s) equivalent to a school summer vacation. ...

Attitudes of Ohio Vocational Agriculture Teachers toward Summer Programs.

ERIC Educational Resources Information Center

Short, Gary E.; Miller, Larry E.

Because many experiences needed by vocational agriculture students typically occur during the summer, the contracts of Ohio vocational agriculture teachers have been longer than the typical 9-month academic school year. A study examined the attitudes of vocational agriculture instructors throughout Ohio toward summer programs so that policymakers…

1995 Summer Opportunities for American Indian Students.

ERIC Educational Resources Information Center

ORBIS Associates, Washington, DC.

This document contains information on summer academic programs offered to American Indian and Alaska Native junior high and high school students. Included are mathematics and science summer programs offered to high school students by the American Indian Science and Engineering Society at universities in Oklahoma, New Mexico, Wisconsin, Iowa,…

The EMERGE Summer Program: Supporting Incoming Freshmen's Success in Mathematics Developmental Coursework

ERIC Educational Resources Information Center

Bird, Katherine; Oppland-Cordell, Sarah; Hibdon, Joseph

2016-01-01

This paper describes the development, results, and future directions of the mathematics component of the EMERGE Summer Program at Northeastern Illinois University. Initiated summer 2014, EMERGE offered English and mathematics sessions for incoming freshmen. The mathematics session aimed to strengthen participants' mathematical foundations,…

Dr. John H. Hopps Jr. Defense Research Scholars Program

DTIC Science & Technology

2014-12-16

Summer 2011) Post -Graduation Plans • Employed as a mechanical engineer at Allegion. • Applying to graduate programs in industrial design and mechanical...Summer 2010) • Multi-Layer Mirror Design for Ultra-Soft X-Rays, Ecole Polytechnique (Summer 2011) Post -Graduation Plans • Post Baccalaureate Research...the year off to work while others planned on strengthening their applications by broadening their research skills in post baccalaureate programs

Freshman Student Perceptions of Academic Programs and Academic Advising. Report No. One. Freshman Appraisal of Pre-Registration Information and Summer Orientation. Freshman Study. Report No. Two.

ERIC Educational Resources Information Center

Zink, Mary S.

An effort was made to determine freshmen student perceptions of academic advisory programs, pre-registration material, and summer orientation. To ascertain these perceptions a questionnaire was sent to all freshmen on the Orono Campus of the University of Maine. Approximately half of the students found the summer orientation program to be helpful,…

Ready for Fall? Near-Term Effects of Voluntary Summer Learning Programs on Low-Income Students' Learning Opportunities and Outcomes. Technical Appendixes

ERIC Educational Resources Information Center

McCombs, Jennifer Sloan; Pane, John F.; Augustine, Catherine H.; Schwartz, Heather L.; Martorell, Paco; Zakaras, Laura

2014-01-01

Prior research has determined that low-income students lose more ground over the summer than their higher-income peers. Prior research has also shown that some summer learning programs can stem this loss, but we do not know whether large, district-run, voluntary programs can improve students' outcomes. To fill this gap, The Wallace Foundation…

Impact of the Extended Learning Opportunities Summer Adventures in Learning (ELO SAIL) Program on Student Academic Performance: Part 1, Results from Fall 2012 to Fall 2015

ERIC Educational Resources Information Center

Cooper-Martin, Elizabeth; Wolanin, Natalie; Jang, Seong; Modarresi, Shahpar; Zhao, Huafang

2016-01-01

Extended Learning Opportunities Summer Adventures in Learning (ELO SAIL) is a Montgomery County Public Schools summer program for students in all Title I elementary schools; it targets students who will be in kindergarten-Grade 2 in the fall following the program. This report analyzed demographic characteristics of attendees and the impact of the…

Building Better Bridges into STEM: A Synthesis of 25 Years of Literature on STEM Summer Bridge Programs

PubMed Central

Ashley, Michael; Cooper, Katelyn M.; Cala, Jacqueline M.; Brownell, Sara E.

2017-01-01

Summer bridge programs are designed to help transition students into the college learning environment. Increasingly, bridge programs are being developed in science, technology, engineering, and mathematics (STEM) disciplines because of the rigorous content and lower student persistence in college STEM compared with other disciplines. However, to our knowledge, a comprehensive review of STEM summer bridge programs does not exist. To provide a resource for bridge program developers, we conducted a systematic review of the literature on STEM summer bridge programs. We identified 46 published reports on 30 unique STEM bridge programs that have been published over the past 25 years. In this review, we report the goals of each bridge program and whether the program was successful in meeting these goals. We identify 14 distinct bridge program goals that can be organized into three categories: academic success goals, psychosocial goals, and department-level goals. Building on the findings of published bridge reports, we present a set of recommendations for STEM bridge programs in hopes of developing better bridges into college. PMID:29146667

Studying Turbulence Using Numerical Simulation Databases, 8. Proceedings of the 2000 Summer Program

NASA Technical Reports Server (NTRS)

2000-01-01

The eighth Summer Program of the Center for Turbulence Research took place in the four-week period, July 2 to July 27, 2000. This was the largest CTR Summer Program to date, involving forty participants from the U. S. and nine other countries. Twenty-five Stanford and NASA-Ames staff members facilitated and contributed to most of the Summer projects. Several new topical groups were formed, which reflects a broadening of CTR's interests from conventional studies of turbulence to the use of turbulence analysis tools in applications such as optimization, nanofluidics, biology, astrophysical and geophysical flows. CTR's main role continues to be in providing a forum for the study of turbulence and other multi-scale phenomena for engineering analysis. The impact of the summer program in facilitating intellectual exchange among leading researchers in turbulence and closely related flow physics fields is clearly reflected in the proceedings.

Evaluation of a Summer Bridge: Critical Component of the Leadership 2.0 Program.

PubMed

Pritchard, Tracy J; Perazzo, Joseph D; Holt, Julie A; Fishback, Benjamin P; McLaughlin, Michaela; Bankston, Karen D; Glazer, Greer

2016-04-01

Summer bridges facilitate the transition from high school to college. Although many schools employ summer bridges, few have published outcomes. This article's purpose is to share preconceptions of college by underrepresented and disadvantaged nursing students and describe important elements and long-term impact of a summer bridge, a component of the Leadership 2.0 program. A longitudinal study design was used to collect baseline, short-term, and long-term post-summer bridge data. Methods included pre- and postsurveys, interviews, and focus groups. After bridge completion, students felt more prepared for the nursing program. Students ranked socialization components as most important. The summer bridge had lasting impact through the first year, where grade point average and retention of underrepresented and disadvantaged bridge students was comparable to the majority first-year students. The summer bridge was effective in preparing nursing students for the first year of college. Through holistic evaluation, unique aspects of socialization critical to student success were uncovered. Copyright 2016, SLACK Incorporated.

Scaling of anomalous Hall effect in Ta/CoFeB/MgAl2O4/Ta multilayers

NASA Astrophysics Data System (ADS)

Wu, Yong; Zhang, Qimeng; Meng, Kangkang; Chen, Jikun; Xu, Xiaoguang; Miao, Jun; Jiang, Yong

2017-06-01

The anomalous Hall effect (AHE) is studied in Ta/CoFeB/MgAl2O4/Ta multilayers with different thicknesses of MgAl2O4 (t), which causes in-plane magnetic anisotropy (IMA) for t = 1.0 nm and perpendicular magnetic anisotropy (PMA) for t ≥ 1.2 nm. Conventional scaling was demonstrated to be not inadequate in our case. The origin of the AHE in Ta/CoFeB/MgAl2O4/Ta multilayers is mainly an extrinsic mechanism. The contribution of skew scattering (SS) is unneglectable, and both the SS and side jump are enhanced when the magnetic anisotropy changes from IMA to PMA, indicating that the oxidation at the interface of CoFeB/MgAl2O4 has a dominant influence on the AHE.

[The retrocapital osteotomy ("chevron") for correction of splayfoot with hallux valgus].

PubMed

Gabel, Michael

2008-12-01

Surgical treatment of hallux valgus deformity with a distal osteotomy of the first metatarsal to address an increased intermetatarsal angle (IMA) I-II. This procedure is combined with a soft-tissue procedure at the first metatarsophalangeal joint: realignment of the first ray, lateral displacement of the first metatarsal head above the sesamoids, rebalancing of the soft tissues at the metatarsophalangeal joint. Pain and soft-tissue inflammation at the bunion, impaired function of the metatarsophalangeal joint, and lateral deviation of the hallux. IMA I-II 10 degrees. Symptomatic osteoarthritis of the first metatarsophalangeal joint, assessed clinically or radiographically. Acute inflammation of the forefoot, osteoporosis of the first metatarsal. Vascular disturbance. Cosmetic indication only. Relative: hypermobility of the first ray, valgus malalignment of the hindfoot, previous retrocapital osteotomy. Lateral soft-tissue release. Resection of the medial pseudoexostosis. V-shaped osteotomy of the distal metatarsal I. Exostosectomy. Lateral displacement of the first metatarsal head. Screw fixation. Realignment of the metatarsophalangeal joint by tightening of the medial soft tissues. Postoperative shoe with full weight bearing. Active exercises of the foot and hallux. Physiotherapy. Prophylaxis of deep vein thrombosis depending on the degree of mobility. Radiographic control after 6 weeks. Bandage or orthosis to maintain toe alignment. IMA I-II was reduced from 13.6 degrees preoperatively to 6.6 degrees postoperatively. HVA decreased from 29.8 degrees to 8.2 degrees postoperatively.

Prospective multicentre study in intensive care units in five cities from the Kingdom of Saudi Arabia: Impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on rates of central line-associated bloodstream infection

PubMed Central

Al-Abdely, Hail M; Alshehri, Areej Dhafer; Rosenthal, Victor Daniel; Mohammed, Yassir Khidir; Banjar, Weam; Orellano, Pablo Wenceslao; Assiri, Abdullah Mufareh; Kader, Nahla Moustafa Abedel; Enizy, Hessa Abdullah Al; Mohammed, Diaa Abdullah; Al-Awadi, Duaa Khalil; Cabato, Analen Fabros; Wasbourne, Maria; Saliya, Randa; Aromin, Rosita Gasmin; Ubalde, Evangelina Balon; Diab, Hanan Hanafy; Alkamaly, Modhi Abdullah; Alanazi, Nawal Mohammed; Hassan Assiry, Ibtesam Yahia; Molano, Apsia Musa; Flores Baldonado, Celia; Al-Azhary, Mohamed; Al Atawi, Sharifa; Molano, Apsia Musa; Al Adwani, Fatima Mohammad; Casuyon Pahilanga, Arlu Marie; Nakhla, Raslan; Al Adwani, Fatma Mohammad; Nair, Deepa Sasithran; Sindayen, Grace; Malificio, Annalyn Amor; Helali, Najla Jameel; Al Dossari, Haya Barjas; Kelany, Ashraf; Algethami, Abdulmajid Ghowaizi; Yanne, Leigh; Tan, Avigail; Babu, Sheema; Abduljabbar, Shatha Mohammad; Bukhari, Syed Zahid; Basri, Roaa Hasan; Mushtaq, Jeyashri Jaji; Rushdi, Hala; Turkistani, Abdullah Abdulaziz; Gonzales Celiz, Jerlie Mae; Al Raey, Mohammed Abdullah; Al-Zaydani Asiri, Ibrahim AM; Aldarani, Saeed Ali; Laungayan Cortez, Elizabeth; Demaisip, Nadia Lynette; Aziz, Misbah Rehman; Omer Abdul Aziz, Ali; Al Manea, Batool; Samy, Eslam; Al-Dalaton, Mervat; Alaliany, Mohammed Jkedeb

2016-01-01

Objective: To analyse the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and INICC Surveillance Online System (ISOS) on central line-associated bloodstream infection (CLABSI) rates in five intensive care units (ICUs) from October 2013 to September 2015. Design: Prospective, before-after surveillance study of 3769 patients hospitalised in four adult ICUs and one paediatric ICU in five hospitals in five cities. During baseline, we performed outcome and process surveillance of CLABSI applying CDC/NHSN definitions. During intervention, we implemented IMA and ISOS, which included: (1) a bundle of infection prevention practice interventions; (2) education; (3) outcome surveillance; (4) process surveillance; (5) feedback on CLABSI rates and consequences; and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed. Results: During baseline, 4468 central line (CL) days and 31 CLABSIs were recorded, accounting for 6.9 CLABSIs per 1000 CL-days. During intervention, 12,027 CL-days and 37 CLABSIs were recorded, accounting for 3.1 CLABSIs per 1000 CL-days. The CLABSI rate was reduced by 56% (incidence-density rate, 0.44; 95% confidence interval, 0.28–0.72; P = 0.001). Conclusions: Implementing IMA through ISOS was associated with a significant reduction in the CLABSI rate in the ICUs of Saudi Arabia. PMID:28989500

Impact of the International Nosocomial Infection Control Consortium (INICC)'s multidimensional approach on rates of ventilator-associated pneumonia in intensive care units in 22 hospitals of 14 cities of the Kingdom of Saudi Arabia.

PubMed

Al-Abdely, Hail M; Khidir Mohammed, Yassir; Rosenthal, Victor D; Orellano, Pablo W; ALazhary, Mohamed; Kaid, Eman; Al-Attas, Anan; Hawsawi, Ghadeer; Kelany, Ashraf; Hussein, Bedoor; Esam, Bayan; Altowerqi, Rami; Alkamaly, Modhi A; Tawfic, Nader A; Cruzpero, Elinita; Al Rashidi, Raya M; Thomas, Reny; Molano, Apsia M; Al Enazy, Hessa A; Al Adwani, Fatima M; Casuyon Pahilanga, Arlu M; Alatawi, Sharifa; Nakhla, Raslan; Al Adwani, Fatma M; Gasmin Aromin, Rosita; Balon Ubalde, Evangelina; Hanafy Diab, Hanan; Kader, Nahla A; Hassan Assiry, Ibtesam Y; Sawan, Fahad A; Ammari, Hassan E; Mashiakhy, Alhasan M; Santiago, Elaine B; Chua, Christian M S; Dalis, Imee M; Arishi, Haider M; Lozada, Ruthelma; Al-Zaydani Asiri, Ibrahim A M; Ahmed, Hala; Jarie, Al; Al-Qathani, Ali S M; Al-Alkami, Halima Y; AlDalaton, Mervat; Alih, Siti J B; Alaliany, Mohammed J; Helali, Najla J; Sindayen, Grace; Malificio, Annalyn A; Al Dossari, Haya B; Algethami, Abdulmajid G; Mohamed, Dia; Yanne, Leigh; Tan, Avigail; Babu, Sheema; Abduljabbar, Shatha M; Rushdi, Hala; Fernandez, Janice; Hussain, Waleed M; Rajavel, Renuga D; Bukhari, Syed Z; Turkistani, Abdullah A; Mushtaq, Jeyashri J; Albeladi, Eida; Aboushoushah, Sally; Qushmaq, Nahed; Shyrine, Leide; Philipose, Jomol; Raees, Mohamed; AbdulKhalik, Nawal S; Madco, Marjory; Abdulghany, Mohd; Manao, Athena; Acostan, Catherine; Safwat, Rania; Halwani, Muhammad; Abdul Aal, Nahla A H; Thomas, Anumol; Abdulatif, Shaymaa M; Ariola, Nelia C; Mutwalli, Aisha H; Ariola, Nelia; Bohlega, Eatedal; Simon, Saly; Damlig, Estelita; Elsherbini, Sherin G; Krishne, Ilama T; Abraham, Sheela; Ali Karrar, Mohammed A; Gosn, Nisreen A; Al Hindi, Abdulaziz A; Jaha, Rasha N; AlQahtani, Saeda M; Abdul Aziz, Ali O; Demaisip, Nadia L; Laungayan Cortez, Elizabeth; Cabato, Analen F; Gonzales Celiz, Jerlie M; Al Raey, Mohammed A; Al Darani, Saeed A; Aziz, Misbah R; Manea, Batool A; Samy, Eslam; Briones, Solita; Krishnan, Radhika; Raees, Saman S M; Tabassum, Kehkashan; Ghalilah, Khalid M; Alradady, Mohamed; Al Qatri, Abdulrahim; Chaouali, Mafaten; Elsisi, Magdy; Aldossary, Hajer A; Al-Suliman, Shehab; Al Talib, Amina A; Albaghly, Nadira; Haqlre Mia, Mohammad E; Al-Gethamy, Manal M; Alamri, Dhafer M; Al-Saadi, Adnan S; Ayugat, Evelyn P; Al Hazazi, Nawaf A; Al Hussain, Modi I; Caminade, Yvonne; Santos, Ann J; Abdulwahab, Mohamed H; Al-Garni, Bushra T A

2018-06-23

To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and use of INICC Surveillance Online System (ISOS) on ventilator-associated pneumonia (VAP) rates in Saudi Arabia from September 2013 to February 2017. A multicenter, prospective, before-after surveillance study on 14,961 patients in 37 intensive care units (ICUs) of 22 hospitals. During baseline, we performed outcome surveillance of VAP applying the definitions of the CDC/NHSN. During intervention, we implemented the IMA and the ISOS, which included: (1) a bundle of infection prevention practice interventions, (2) education, (3) outcome surveillance, (4) process surveillance, (5) feedback on VAP rates and consequences and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed using generalized linear mixed models to estimate the effect of intervention. The baseline rate of 7.84 VAPs per 1000 mechanical-ventilator (MV)-days-with 20,927 MV-days and 164 VAPs-, was reduced to 4.74 VAPs per 1000 MV-days-with 118,929 MV-days and 771 VAPs-, accounting for a 39% rate reduction (IDR 0.61; 95% CI 0.5-0.7; P 0.001). Implementing the IMA was associated with significant reductions in VAP rates in ICUs of Saudi Arabia. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Vagal sensory innervation of the gastric sling muscle and antral wall: implications for gastro-esophageal reflux disease?

PubMed

Powley, T L; Gilbert, J M; Baronowsky, E A; Billingsley, C N; Martin, F N; Phillips, R J

2012-10-01

The gastric sling muscle has not been investigated for possible sensory innervation, in spite of the key roles the structure plays in lower esophageal sphincter (LES) function and gastric physiology. Thus, the present experiment used tracing techniques to label vagal afferents and survey their projections in the lesser curvature. Sprague-Dawley rats received injections of dextran biotin into the nodose ganglia. Fourteen days postinjection, animals were euthanized and their stomachs were processed to visualize the vagal afferent innervation. In different cases, neurons, muscle cells, or interstitial cells of Cajal (ICC) were counterstained. The sling muscle is innervated throughout its length by vagal afferent intramuscular arrays (IMAs) associated with ICC. In addition, the distal antral attachment site of the sling muscle is innervated by a novel vagal afferent terminal specialization, an antral web ending. The muscle wall of the distal antrum is also innervated by conventional IMAs and intraganglionic laminar endings, the two types of mechanoreceptors found throughout stomach smooth muscle. The innervation of sling muscle by IMAs, putative stretch receptors, suggests that sling sensory feedback may generate vago-vagal or other reflexes with vagal afferent limbs. The restricted distribution of afferent web endings near the antral attachments of sling fibers suggests the possibility of specialized mechanoreceptor functions linking antral and pyloric activity to the operation of the LES. Dysfunctional sling afferents could generate LES motor disturbances, or normative compensatory sensory feedback from the muscle could compromise therapies targeting only effectors. © 2012 Blackwell Publishing Ltd.

Designing a Summer Transition Program for Incoming and Current College Students on the Autism Spectrum: A Participatory Approach.

PubMed

Hotez, Emily; Shane-Simpson, Christina; Obeid, Rita; DeNigris, Danielle; Siller, Michael; Costikas, Corinna; Pickens, Jonathan; Massa, Anthony; Giannola, Michael; D'Onofrio, Joanne; Gillespie-Lynch, Kristen

2018-01-01

Students with Autism Spectrum Disorder (ASD) face unique challenges transitioning from high school to college and receive insufficient support to help them navigate this transition. Through a participatory collaboration with incoming and current autistic college students, we developed, implemented, and evaluated two intensive week-long summer programs to help autistic students transition into and succeed in college. This process included: (1) developing an initial summer transition program curriculum guided by recommendations from autistic college students in our ongoing mentorship program, (2) conducting an initial feasibility assessment of the curriculum [Summer Transition Program 1 (STP1)], (3) revising our initial curriculum, guided by feedback from autistic students, to develop a curriculum manual, and (4) pilot-testing the manualized curriculum through a quasi-experimental pre-test/post-test assessment of a second summer program [Summer Transition Program 2 (STP2)]. In STP2, two autistic college students assumed a leadership role and acted as "mentors" and ten incoming and current autistic college students participated in the program as "mentees." Results from the STP2 pilot-test suggested benefits of participatory transition programming for fostering self-advocacy and social skills among mentees. Autistic and non-autistic mentors (but not mentees) described practicing advanced forms of self-advocacy, specifically leadership, through their mentorship roles. Autistic and non-autistic mentors also described shared (e.g., empathy) and unique (an intuitive understanding of autism vs. an intuitive understanding of social interaction) skills that they contributed to the program. This research provides preliminary support for the feasibility and utility of a participatory approach in which autistic college students are integral to the development and implementation of programming to help less experienced autistic students develop the self-advocacy skills they will need to succeed in college.

Designing a Summer Transition Program for Incoming and Current College Students on the Autism Spectrum: A Participatory Approach

PubMed Central

Hotez, Emily; Shane-Simpson, Christina; Obeid, Rita; DeNigris, Danielle; Siller, Michael; Costikas, Corinna; Pickens, Jonathan; Massa, Anthony; Giannola, Michael; D'Onofrio, Joanne; Gillespie-Lynch, Kristen

2018-01-01

Students with Autism Spectrum Disorder (ASD) face unique challenges transitioning from high school to college and receive insufficient support to help them navigate this transition. Through a participatory collaboration with incoming and current autistic college students, we developed, implemented, and evaluated two intensive week-long summer programs to help autistic students transition into and succeed in college. This process included: (1) developing an initial summer transition program curriculum guided by recommendations from autistic college students in our ongoing mentorship program, (2) conducting an initial feasibility assessment of the curriculum [Summer Transition Program 1 (STP1)], (3) revising our initial curriculum, guided by feedback from autistic students, to develop a curriculum manual, and (4) pilot-testing the manualized curriculum through a quasi-experimental pre-test/post-test assessment of a second summer program [Summer Transition Program 2 (STP2)]. In STP2, two autistic college students assumed a leadership role and acted as “mentors” and ten incoming and current autistic college students participated in the program as “mentees.” Results from the STP2 pilot-test suggested benefits of participatory transition programming for fostering self-advocacy and social skills among mentees. Autistic and non-autistic mentors (but not mentees) described practicing advanced forms of self-advocacy, specifically leadership, through their mentorship roles. Autistic and non-autistic mentors also described shared (e.g., empathy) and unique (an intuitive understanding of autism vs. an intuitive understanding of social interaction) skills that they contributed to the program. This research provides preliminary support for the feasibility and utility of a participatory approach in which autistic college students are integral to the development and implementation of programming to help less experienced autistic students develop the self-advocacy skills they will need to succeed in college. PMID:29487547

NASA Ambassadors: A Speaker Outreach Program

NASA Technical Reports Server (NTRS)

McDonald, Malcolm W.

1998-01-01

The work done on this project this summer has been geared toward setting up the necessary infrastructure and planning to support the operation of an effective speaker outreach program. The program has been given the name, NASA AMBASSADORS. Also, individuals who become participants in the program will be known as "NASA AMBASSADORS". This summer project has been conducted by the joint efforts of this author and those of Professor George Lebo who will be issuing a separate report. The description in this report will indicate that the NASA AMBASSADOR program operates largely on the contributions of volunteers, with the assistance of persons at the Marshall Space Flight Center (MSFC). The volunteers include participants in the various summer programs hosted by MSFC as well as members of the NASA Alumni League. The MSFC summer participation programs include: the Summer Faculty Fellowship Program for college and university professors, the Science Teacher Enrichment Program for middle- and high-school teachers, and the NASA ACADEMY program for college and university students. The NASA Alumni League members are retired NASA employees, scientists, and engineers. The MSFC offices which will have roles in the operation of the NASA AMBASSADORS include the Educational Programs Office and the Public Affairs Office. It is possible that still other MSFC offices may become integrated into the operation of the program. The remainder of this report will establish the operational procedures which will be necessary to sustain the NASA AMBASSADOR speaker outreach program.

Summer Upward Bound, Terre Haute, Indiana. Secondary Program in Compensatory Education, 4.

ERIC Educational Resources Information Center

American Institutes for Research in the Behavioral Sciences, Palo Alto, CA.

Upward Bound was a precollege program geared for high school students with potential who had been handicapped by economic, cultural, and educational deprivation. It involved a full-time summer program and follow-up programs (counseling, cultural activities, and physical education) during the academic year. Students stayed in the program for three…

A Quantitative Analysis of an Arts Program

ERIC Educational Resources Information Center

Gallagher, Faustina

2013-01-01

This study assessed the relationship of an Arts Summer Learning Program (Arts Program) to student academic performance and college readiness. A North Texas school district collaborated with a research-based Arts Program in 2010, and a new approach was implemented in the summer school program for low-performing students who had failed courses in…

The Los Alamos Space Weather Summer School: Career and Research Benefits to Students and Mentors

NASA Astrophysics Data System (ADS)

Cowee, M.

2014-12-01

This last summer we held the 4th Los Alamos Space Weather Summer School. This 8-week long program is designed for mid-career graduate students in related fields to come to LANL, receive lectures on space physics and space environment topics, and carry out a research project under the mentorship of LANL staff members. On average we have accepted ~10 students per year to the program, with a strong applicant pool to choose from. This type of summer school program is relatively unique in the space physics community—there are several other summer schools but they are of shorter duration and do not include the mentor-research project aspect which builds a strong one-on-one connection between the summer student and his/her LANL mentor(s). From the LANL perspective, this program was intended to have several benefits including building collaborations between LANL staff and universities and recruitment of potential postdocs. From the student perspective, this program is not only an educational opportunity but a strong networking opportunity and a chance to enhance their professional skills and publication record. Students are permitted to work on projects directly related to their thesis or on projects in areas that are completely new to them. At the end of the summer school, the students also develop their presentation skills by preparing and giving 20 min presentations on their research projects to the research group. Over the past four years the summer school has increased in popularity, and the feedback from the student participants has been very positive. Alumni of the program have continued collaborations with their mentors, resulting in publications and conference presentations, and one postdoc hire to date.

The Los Alamos Space Weather Summer School: Career and Research Benefits to Students and Mentors

NASA Astrophysics Data System (ADS)

Cowee, M.

2015-12-01

This last summer we held the 5th Los Alamos Space Weather Summer School. This 8-week long program is designed for mid-career graduate students in related fields to come to LANL, receive lectures on space physics and space environment topics, and carry out a research project under the mentorship of LANL staff members. We accept typically 6-8 students to the program, with a strong applicant pool to choose from. This type of summer school program is relatively unique in the space physics community—there are several other summer schools but they are of shorter duration and do not include the mentor-research project aspect which builds a strong one-on-one connection between the summer student and his/her LANL mentor(s). From the LANL perspective, this program was intended to have several benefits including building collaborations between LANL staff and universities and recruitment of potential postdocs. From the student perspective, this program is not only an educational opportunity but a strong networking opportunity and a chance to enhance their professional skills and publication record. Students are permitted to work on projects directly related to their thesis or on projects in areas that are completely new to them. At the end of the summer school, the students also develop their presentation skills by preparing and giving AGU-style presentations on their research projects to the research group. Over the past five years the summer school has increased in popularity, and the feedback from the student participants has been very positive. Alumni of the program have continued collaborations with their mentors, resulting in publications and conference presentations, and one postdoc hire to date.

A 10-Year Review of the Food Science Summer Scholars Program: A Model for Research Training and for Recruiting Undergraduate Students into Graduate Programs and Careers in Food Science

ERIC Educational Resources Information Center

Roberts, Angela J.; Robbins, Janette; McLandsborough, Lynne; Wiedmann, Martin

2010-01-01

A pressing problem facing regulatory agencies, academia, and the food industry is a shortage of qualified food science graduates, particularly those with advanced degrees (that is, M.S. or Ph.D.). In 2000, the Cornell Institute of Food Science established the annual Food Science Summer Scholars Program as an experiential summer research program…

Super Summer Safari Manual: 1989 Summer Library Program. Bulletin No. 9240.

ERIC Educational Resources Information Center

Roeber, Jane A., Ed.

Based on the theme, "Super Summer Safari: Make Books Your Big Game," this manual describes library activities intended to stimulate family explorations of local and regional natural environments, of urban parks, and of agricultural settings. The manual is divided into 6 sections: (1) "Planning and Promoting Programs"; (2)…

United States Air Force Summer Research Program -- 1993. Volume 13. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Kirtland Air Force Base, Albuquerque, NM August 1993 14-1 My Summer Apprenticeship At Kirtland Air Force Base, Phillips Laboratory Andrea Garcia...AFOSR Summer Research Program Phillips Laboratory Sponsored By: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, NM... Phillips Laboratory Sponsored by: Air

76 FR 5328 - Summer Food Service Program; 2011 Reimbursement Rates

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

.... Since January 1, 2008, reimbursement has been based solely on a ``meals times rates'' calculation... public of the annual adjustments to the reimbursement rates for meals served in the Summer Food Service... reimbursement rates for meals served in the Summer Food Service Program (SFSP). In accordance with sections 12(f...

After School Centers Project. Final Reports. Winter 1968-1969; Summer 1969.

ERIC Educational Resources Information Center

Harvard Univ., Cambridge, MA. Graduate School of Education.

Two final reports, winter 1968-1969 and summer 1969, respectively describe the sixth and seventh sessions of the Cambridge School Department's After School Center Program and involving six elementary schools. Both the winter and the summer programs were designed to give disadvantaged children remedial instruction in reading and mathematics along…

Summer Training and Education Program (STEP): Report on the 1987 Experience.

ERIC Educational Resources Information Center

Sipe, Cynthia L.; And Others

The Summer Training and Education Program (STEP) was developed in 1984 as a strategy for reducing the number of young people who leave school without the skills and motivation necessary for productive employment. The STEP intervention involves collaboration between the public schools and the federal Summer Youth Employment and Training Program…

"Learning City" Summer Migrant Program.

ERIC Educational Resources Information Center

Presson, Johnny E.; Baker, Wilbur L.

"Learning City" is the theme of a summer education project that provides a unique teaching atmosphere for migrant children. For 2 summers, 130 students have participated in this program that sustains and enforces reading and math skills, as well as helps develop self-concept. Industries in Learning City are the various branches of study: reading…

Dietary intake of children participating in the USDA Summer Food Service Program

USDA-ARS?s Scientific Manuscript database

The USDA summer food service program (SFSP) provides free lunches during the summer. This study examined the foods selected and consumed by participating children. Three hundred and two children were observed in 14 schools during a 4-week period in June, 2011; 50% were male; 75% were in elementary s...

Teacher Preparation: A High Intensity Integrated Social Studies Summer Program in a Clinical Setting.

ERIC Educational Resources Information Center

Van Cleaf, David W.; And Others

This paper describes and evaluates a summer program in teacher education--Summer Adventure in Learning (SAIL). The project's major objective was to help preservice teachers design educational materials which would improve the reading accuracy and comprehension of their students. Primary objectives of project SAIL were to provide field-based…

Summer HILT Experience: ESL and SSL for Elementary School.

ERIC Educational Resources Information Center

Garcia, Marilyn; Grady, Karen

A high intensity language training (HILT) summer program in English as a second language and Spanish as a second language offered to second through eighth grade students in the North Monterey County Unified School District (California) during the summers of 1982 and 1983 is described. The program funding, design, admission, development, and…

The Impact of a Summer Reading Intervention on Academic Achievemement

ERIC Educational Resources Information Center

Walsh, Jonathan T.

2017-01-01

With so many students attending summer programs, it is remarkable that there is little research available aiming to investigate achievement differences in participants versus non-participants. This study examined the place of a summer program within a school district budget and curriculum. The study was designed to better understand the…

Children's Activity Levels and Lesson Context during Summer Swim Instruction

ERIC Educational Resources Information Center

Schwamberger, Benjamin; Wahl-Alexander, Zachary

2016-01-01

Summer swim programs provide a unique opportunity to engage children in PA as well as an important lifesaving skill. Offering summer swim programs is critical, especially for minority populations who tend to have higher rates of drowning, specifically in youth populations. The purpose of this study was to determine the lesson context and…

Summer Youth Program in Rail and Intermodal Transportation.

DOT National Transportation Integrated Search

2016-02-22

For the past five years, Michigan Technological University has been running a Summer Youth Program (SYP) in Rail and Intermodal Transportation. The program has seen continuous growth along with a diverse group of students, grades 9-11. The structure ...

NASA Ames Summer High School Apprenticeship Research Program

NASA Technical Reports Server (NTRS)

Powell, P.

1985-01-01

The Summer High School Apprenticeship Research Program (SHARP) is described. This program is designed to provide engineering experience for gifted female and minority high school students. The students from this work study program which features trips, lectures, written reports, and job experience describe their individual work with their mentors.

Mix It Up! Six Ways To Rethink Tired Summer Reading Programs.

ERIC Educational Resources Information Center

Barstow, Barbara; Markey, Penny

1997-01-01

Presents six ideas to improve public libraries' summer reading programs. Highlights include creating Web sites; marketing directly to parents rather than to schools through direct mail and collaborative promotion; statewide cooperative programs; the use of teen volunteers; scratch-off game cards; and off-site programs. (LRW)

METRO Achievement Program: Summer 1988. External Evaluation Report.

ERIC Educational Resources Information Center

Thompson, Denise R.

This document comprises an evaluation of the 1988 METRO Achievement Program, a summer educational program to help develop the academic potential of primarily Black and Hispanic girls entering the seventh and eighth grades in Chicago. The 5-week program included the following components: (1) mathematics, science, and communication skills classes;…

College Summer Programs for High School Students: Outreach, Recruitment, Enrichment.

ERIC Educational Resources Information Center

Nusbaum, Kenneth E.

1998-01-01

Describes an Auburn University (Alabama) summer program that brings high school students into the veterinary medicine and molecular biology programs, focusing on recruitment and selection of students, aspects of faculty participation, parent involvement, orientation, laboratory work, and student grouping and mentoring. Results of the program to…

Building Quality in Summer Learning Programs: Approaches and Recommendations

ERIC Educational Resources Information Center

McLaughlin, Brenda; Pitcock, Sarah

2009-01-01

This report identifies the different settings in which summer programs for disadvantaged youth most commonly take place--schools, parks and recreation departments, community--and faith-based organizations, and child-care programs-- and examines the limitations and opportunities presented by each in building better programming. It reviews broadly…

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 5A. Wright Laboratory

DTIC Science & Technology

1992-12-01

1992 6-~1 SOME RESULTS IN MACIIINE- LEARNING Mike Breen Assistant Professor Department of Mathematics Tennessee Technological Universitv Abstract The...Research Laboratory; Wilford Hall Medical Center 12 High School Apprenticeship Program Reports: Armstrong Laboratory 13 High School Apprenticeship ...Program Reports: Phillips Laboratory 14 High School Apprenticeship Program Reports: Rome Laboratory 15 High School Apprenticeship Program Reports

Summer Opportunities.

ERIC Educational Resources Information Center

Winds of Change, 2002

2002-01-01

This directory describes 24 summer internships and cooperative education programs for college students, especially in the science, engineering, and technology fields. A few programs are specifically for American Indians, minority groups, or college-bound high school students. Program entries include a brief description, skills and background…

Summer of Innovation Kick Off

NASA Image and Video Library

2010-06-09

Erin Gilbert, Director of Professional Development from the National Summer Learning Associations, motivates teachers and middle school students during the kick off of NASA's Summer of Innovation program at the Jet Propulsion Laboratory in Pasadena, Calif., Thursday, June 10, 2010. Through the program, NASA will engage thousands of middle school students and teachers in stimulating math and science-based education programs with the goal of increasing the number of future scientists, mathematicians, and engineers. Photo Credit: (NASA/Bill Ingalls)

The National Astronomy Consortium Summer Student Research Program at NRAO-Socorro: Year 2 structure

NASA Astrophysics Data System (ADS)

Mills, Elisabeth A.; Sheth, Kartik; Giles, Faye; Perez, Laura M.; Arancibia, Demian; Burke-Spolaor, Sarah

2016-01-01

I will present a summary of the program structure used for the second year of hosting a summer student research cohort of the National Astronomy Consortium (NAC) at the National Radio Astronomy Observatory in Socorro, NM. The NAC is a program partnering physics and astronomy departments in majority and minority-serving institutions across the country. The primary aim of this program is to support traditionally underrepresented students interested in pursuing a career in STEM through a 9-10 week summer astronomy research project and a year of additional mentoring after they return to their home institution. I will describe the research, professional development, and inclusivity goals of the program, and show how these were used to create a weekly syllabus for the summer. I will also highlight several unique aspects of this program, including the recruitment of remote mentors for students to better balance the gender and racial diversity of available role models for the students, as well as the hosting of a contemporaneous series of visiting diversity speakers. Finally, I will discuss structures for continuing to engage, interact with, and mentor students in the academic year following the summer program. A goal of this work going forward is to be able to make instructional and organizational materials from this program available to other sites interested in joining the NAC or hosting similar programs at their own institution.

20 CFR 632.250 - General.

Code of Federal Regulations, 2012 CFR

2012-04-01

... AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.250 General. This subpart contains the policies, rules, and regulations of the Department in implementing and administering a Summer...

20 CFR 632.250 - General.

Code of Federal Regulations, 2010 CFR

2010-04-01

... AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.250 General. This subpart contains the policies, rules, and regulations of the Department in implementing and administering a Summer...

20 CFR 632.250 - General.

Code of Federal Regulations, 2011 CFR

2011-04-01

... AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.250 General. This subpart contains the policies, rules, and regulations of the Department in implementing and administering a Summer...

Effectiveness of Structured Teacher Adaptations to an Evidence-Based Summer Literacy Program

ERIC Educational Resources Information Center

Kim, James S.; Burkhauser, Mary A.; Quinn, David M.; Guryan, Jonathan; Kingston, Helen Chen; Aleman, Kirsten

2017-01-01

The authors conducted a cluster-randomized trial to examine the effectiveness of structured teacher adaptations to the implementation of an evidence-based summer literacy program that provided students with (a) books matched to their reading level and interests and (b) teacher scaffolding for summer reading in the form of end-of-year comprehension…

76 FR 72996 - 60-Day Notice of Proposed Information Collection: Form DS-7007, Summer Work Travel Job Placement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-28

.... SUMMARY: The Department of State is seeking Office of Management and Budget (OMB) approval for the... the Paperwork Reduction Act of 1995. Title of Information Collection: Exchange Visitor Program--Summer...: Entities designated by the Department of State as Exchange Visitor Program sponsors in the Summer Work...

Summer Bookaneers: Sign on with Captain Book. 1990 Florida Summer Library Program.

ERIC Educational Resources Information Center

Fiore, Carole D., Comp.; Fine, Jana R., Comp.

Designed for use by children's librarians in organizing and conducting a summer reading program for children 5 through 12 years of age, this "log book" contains suggestions for activities related to a seafaring theme together with lists of selected materials relevant to the particular activities. Samples of a press release and several…

The Effects of Experiential, Service-Learning Summer Learning Programs on Youth Outcomes

ERIC Educational Resources Information Center

Greenman, Adam

2014-01-01

This study examines whether summer programming that relies on the delivery of a hands-on, experiential service learning curriculum to deliver content is able to reduce or eliminate summer learning loss in middle school students. Using Alexander, Entwisle, and Olson's (2001) faucet theory as a theoretical framework and a qualitative case study…

75 FR 10843 - Special Summer Postal Rate Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

..., Pricing Strategy, as the official available to provide prompt responses to requests for clarification from... special volume pricing incentive for certain Standard Mail this summer. This document announces... Standard Mail Volume Incentive Pricing Program (Standard Mail Incentive Program) similar to the one...

The State of the Summer: a Review of Child Summer Weight Gain and Efforts to Prevent It.

PubMed

Tanskey, Lindsay A; Goldberg, Jeanne; Chui, Kenneth; Must, Aviva; Sacheck, Jennifer

2018-06-01

Accumulating evidence shows that children in the USA gain weight more rapidly during the summer, when school is not in session. This narrative review spanning 2007 to 2017 summarizes efforts to characterize the problem, identify key determinants, and intervene to prevent excess summer weight gain. Summer weight gain remains a concern for elementary-age youth. Few studies have examined its determinants, but unfavorable summertime shifts in diet, physical activity, sedentary time, screen media use, and sleep have been reported. Increased structure is thought to protect against summer weight gain. Interventions to support physical activity and nutrition during the summer show promise, though large-scale impact on weight outcomes remains to be seen. Supporting health behaviors during the summer remains a priority for obesity prevention researchers, practitioners, and policymakers. Strategies to expand access to structured programs and reach beyond such programs to improve behaviors at home are of particular importance.

Attributions, Influences and Outcomes for Underrepresented and Disadvantaged Participants of a Medical Sciences Enrichment Pipeline Program

ERIC Educational Resources Information Center

Pinckney, Charlyene Carol

2014-01-01

The current study was undertaken to examine the effectiveness of the Rowan University-School of Osteopathic Medicine - Summer Pre-Medical Research and Education Program (Summer PREP), a postsecondary medical sciences enrichment pipeline program for under-represented and disadvantaged students. Thirty-four former program participants were surveyed…

Once upon a Tale. 1995 Florida Library Youth Program.

ERIC Educational Resources Information Center

Abramoff, Carolann Palm, Comp.; And Others

The Florida Library Youth Program is an extension of the Florida Summer Library Program. Many libraries have wanted to provide programs for school-age children at times other than the traditional summer vacation, and this guide responds to their needs. The theme, "Once Upon a Tale," focuses on folklore, stories, and storytelling. The…

Proceedings from the Communication Across the Curriculum Strand. NCA 2001 Summer Conference: Engaging 21st Century Communication Students.

ERIC Educational Resources Information Center

Dannels, Deanna; Jackson, Nancy; Robertson, Terry; Sheckles, Ted; Tomlinson, Stephanie

This Proceedings from the Communication across the Curriculum (CXC) strand of the National Communication Association's 2001 Summer Conference first highlights and describes five of the most common types of programs across the nation: Speaking Intensive Programs, Combined Speaking and Writing Programs, Discipline-Specific Programs, Faculty…

A Robustness Testing Campaign for IMA-SP Partitioning Kernels

NASA Astrophysics Data System (ADS)

Grixti, Stephen; Lopez Trecastro, Jorge; Sammut, Nicholas; Zammit-Mangion, David

2015-09-01

With time and space partitioned architectures becoming increasingly appealing to the European space sector, the dependability of partitioning kernel technology is a key factor to its applicability in European Space Agency projects. This paper explores the potential of the data type fault model, which injects faults through the Application Program Interface, in partitioning kernel robustness testing. This fault injection methodology has been tailored to investigate its relevance in uncovering vulnerabilities within partitioning kernels and potentially contributing towards fault removal campaigns within this domain. This is demonstrated through a robustness testing case study of the XtratuM partitioning kernel for SPARC LEON3 processors. The robustness campaign exposed a number of vulnerabilities in XtratuM, exhibiting the potential benefits of using such a methodology for the robustness assessment of partitioning kernels.

Subcaptial oblique fifth metatarsal osteotomy versus distal chevron osteotomy for correction of bunionette deformity: a cadaveric study.

PubMed

Cooper, Minton Truitt; Coughlin, Michael J

2012-10-01

The aim of this study was to compare a distal subcapital oblique fifth metatarsal with a distal chevron osteotomy for correction of bunionette deformity. Twenty cadaveric feet were randomly assigned to undergo either a subcapital oblique or chevron osteotomy of the distal fifth metatarsal. Radiographic measurements, including 4-5 intermetatarsal angle (IMA), fifth metatarsophalangeal angle (5-MPA) and foot width, were compared between the 2 groups. Foot width and 5-MPA was significantly decreased in both groups with no difference between the groups. The 4-5 IMA was not significantly altered in either group. Decrease in foot width and 5-MPA was similarly achieved with either distal chevron or subcapital oblique osteotomy of the fifth metatarsal in normal cadaveric specimens. No significant difference was found between the 2 techniques in any of the radiographic parameters measured.

20 CFR 628.700 - Scope and purpose.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROGRAMS UNDER TITLE II OF THE JOB TRAINING PARTNERSHIP ACT The Summer Youth Employment and Training Program § 628.700 Scope and purpose. This subpart contains the regulations for the Summer Youth Employment and Training Program (SYETP...

The ASSURE Summer REU Program: Introducing research to first-generation and underserved undergraduates through space sciences and engineering projects

NASA Astrophysics Data System (ADS)

Barron, Darcy; Peticolas, Laura; Multiverse Team at UC Berkeley's Space Sciences Lab

2018-01-01

The Advancing Space Science through Undergraduate Research Experience (ASSURE) summer REU program is an NSF-funded REU site at the Space Sciences Lab at UC Berkeley that first started in summer 2014. The program recruits students from all STEM majors, targeting underserved students including community college students and first-generation college students. The students have little or no research experience and a wide variety of academic backgrounds, but have a shared passion for space sciences and astronomy. We will describe our program's structure and the components we have found successful in preparing and supporting both the students and their research advisors for their summer research projects. This includes an intensive first week of introductory lectures and tutorials at the start of the program, preparing students for working in an academic research environment. The program also employs a multi-tiered mentoring system, with layers of support for the undergraduate student cohort, as well as graduate student and postdoctoral research advisors.

Collaborative Aerospace Research and Fellowship Program at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Heyward, Ann O.; Kankam, Mark D.

2004-01-01

During the summer of 2004, a 10-week activity for university faculty entitled the NASA-OAI Collaborative Aerospace Research and Fellowship Program (CFP) was conducted at the NASA Glenn Research Center in collaboration with the Ohio Aerospace Institute (OAI). This is a companion program to the highly successful NASA Faculty Fellowship Program and its predecessor, the NASA-ASEE Summer Faculty Fellowship Program that operated for 38 years at Glenn. The objectives of CFP parallel those of its companion, viz., (1) to further the professional knowledge of qualified engineering and science faculty,(2) to stimulate an exchange of ideas between teaching participants and employees of NASA, (3) to enrich and refresh the research and teaching activities of participants institutions, and (4) to contribute to the research objectives of Glenn. However, CFP, unlike the NASA program, permits faculty to be in residence for more than two summers and does not limit participation to United States citizens. Selected fellows spend 10 weeks at Glenn working on research problems in collaboration with NASA colleagues and participating in related activities of the NASA-ASEE program. This year's program began officially on June 1, 2004 and continued through August 7, 2004. Several fellows had program dates that differed from the official dates because university schedules vary and because some of the summer research projects warranted a time extension beyond the 10 weeks for satisfactory completion of the work. The stipend paid to the fellows was $1200 per week and a relocation allowance of $1000 was paid to those living outside a 50-mile radius of the Center. In post-program surveys from this and previous years, the faculty cited numerous instances where participation in the program has led to new courses, new research projects, new laboratory experiments, and grants from NASA to continue the work initiated during the summer. Many of the fellows mentioned amplifying material, both in undergraduate and graduate courses, on the basis of the summer s experience at Glenn. A number of 2004 fellows indicated that proposals to NASA will grow out of their summer research projects. In addition, some journal articles and NASA publications will result from this past summer s activities. Fellows from past summers continue to send reprints of articles that resulted from work initiated at Glenn. This report is intended primarily to summarize the research activities comprising the 2004 CFP Program at Glenn. Particular research studies include: 1) Development of an Imaging-Based, Computational Fluid Dynamics Tool to Assess Fluid Mechanics in Experimental Models that Simulate Blood Vessels; 2) Analysis of Nanomaterials Produced from Precursors; and 3) LEO Propagation Analysis Tool.

A geometric analysis of hallux valgus: correlation with clinical assessment of severity

PubMed Central

Piqué-Vidal, Carlos; Vila, Joan

2009-01-01

Background Application of plane geometry to the study of bunion deformity may represent an interesting and novel approach in the research field of hallux valgus. For the purpose of contributing to development of a different perspective in the assessment of hallux valgus, this study was conducted with three objectives: a) to determine the position on the intersection point of the perpendicular bisectors of the longitudinal axes of the first metatarsal and proximal phalanx (IP), b) to correlate the location of this point with hallux valgus deformity according to angular measurements and according to visual assessment of the severity carried out by three independent observers, and c) to assess whether this IP correlated with the radius of the first metatarsophalangeal arc circumference. Methods Measurements evaluated were intermetatarsal angle (IMA), hallux valgus angle (HVA), and proximal phalangeal articular angle (PPAA). The Autocad® program computed the location of the IP inside or outside of the foot. Three independent observers rated the severity of hallux valgus in photographs using a 100-mm visual analogue scale (VAS). Results Measurements of all angles except PPAA showed significantly lower values when the IP was located out of the foot more distantly and vice versa, significantly higher values for severe deformities in which the IP was found inside the foot (p < 0.001). The IP correlated significantly with VAS scores and with the length of the radius of the circle that included the first metatarsophalangeal arc circumference (p < 0.001) Conclusion The IP is a useful indicator of hallux valgus deformity because correlated significantly with IMA and HVA measurements, VAS scores obtained by visual inspection of the degree of deformity, and location of the center of the first metatarsophalangeal arc circumference. PMID:19442286

Summer Training and Education Program (STEP): The Experience of Hispanic Participants in the Summer of 1985.

ERIC Educational Resources Information Center

Sipe, Cynthia L.

The performance of Hispanic participants in the Summer Training and Education Program (STEP) was examined in detail because findings about short-term outcomes for the first year of STEP operation were more promising for Hispanics than for members of other ethnic groups. In addition, Hispanic performance was examined because of the relatively poor…

Supporting the Summer Reading of Urban Youth: An Evaluation of the Baltimore SummerREADS Program

ERIC Educational Resources Information Center

Stein, Marc L.

2017-01-01

This article presents an evaluation of the first 2 years of a research-based summer learning program that provided self-selected and developmentally appropriate books to students in low-income and low-resource elementary schools by a local philanthropic organization in a large urban district. The evaluation found evidence of a positive effect of…

Active Summers Matter: Evaluation of a Community-Based Summertime Program Targeting Obesogenic Behaviors of Low-Income, Ethnic Minority Girls

ERIC Educational Resources Information Center

Bohnert, Amy M.; Ward, Amanda K.; Burdette, Kimberly A.; Silton, Rebecca L.; Dugas, Lara R.

2014-01-01

Low-income minority females are disproportionately affected by obesity. The relevance of summer months to weight gain is often overlooked. Some evidence suggests that summer programming, such as day camps, may offer increased opportunities for structured physical activities resulting in less weight gain. This study examined the effectiveness of…

Replicating the Moderating Role of Income Status on Summer School Effects across Subject Areas: A Meta-Analysis

ERIC Educational Resources Information Center

Quinn, David M.; Lynch, Kathleen; Kim, James S.

2014-01-01

The finding that academic summer programs are effective for low income students has been replicated across meta-analytic reviews. However, these reviews have yielded contradictory evidence about whether summer programs are more effective for lower- or higher-income students. This discrepancy may be due to income-based differences in the summer…

Portland Schools Foundation Ninth Grade Counts: Student Data Report--Outcomes and Participation for Summer 2009 and Participation for Summer 2010

ERIC Educational Resources Information Center

Northwest Evaluation Association, 2011

2011-01-01

The Portland Schools Foundation's (PSF) Ninth Grade Counts initiative is a network of more than twenty independent summer transition programs targeting Academic Priority (or "at-risk") students. These programs share a common focus on providing academic support, enrichment, and career/college exposure for students who show early warning…

20 CFR 628.700 - Scope and purpose.

Code of Federal Regulations, 2011 CFR

2011-04-01

... THE JOB TRAINING PARTNERSHIP ACT The Summer Youth Employment and Training Program § 628.700 Scope and purpose. This subpart contains the regulations for the Summer Youth Employment and Training Program (SYETP...

20 CFR 628.700 - Scope and purpose.

Code of Federal Regulations, 2012 CFR

2012-04-01

... THE JOB TRAINING PARTNERSHIP ACT The Summer Youth Employment and Training Program § 628.700 Scope and purpose. This subpart contains the regulations for the Summer Youth Employment and Training Program (SYETP...

Summer Learning That Sticks

ERIC Educational Resources Information Center

Browne, Daniel

2017-01-01

A new RAND Corporation study shows that voluntary summer programs can benefit children from low-income families, particularly those with high attendance. Programs studied in five school districts had several elements in common: a mix of academics and enrichment activities, certified teachers, small class sizes, full-day programming provided five…

1994 Winds of Change Guide to Summer Co-ops, Internships and Minority School Programs.

ERIC Educational Resources Information Center

Winds of Change, 1994

1994-01-01

Profiles 40 companies, agencies, and colleges that offer summer internships and cooperative education programs for American Indian high school, college, and graduate students. Includes program descriptions, prerequisites, deadline and requirements for application, and name and address of contact persons. (LP)

Book Banquet. A Summer Reading Program Manual.

ERIC Educational Resources Information Center

Ward, Caroline; Levine, Joyce

This manual for the 1993 New York State summer reading program, "Book Banquet," ties books and reading together with the theme of eating. The manual offers program ideas, activities, and materials. The following chapters are included: (1) "Appetizers" (planning, publicity, and promotion); (2) "Setting the Table"…

Summer Research Program (1992). Graduate Student Research Program (GSRP) Reports. Volume 8. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Research Program Starfire Optical Range, Phillips Laboratory /LITE Kirtland Air Force Base, Albuquerque, NM 87117 Sponsored by: Air ... Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico September, 1992 18-1 PROGRESS...Report for: Summer Research Program Phillips Laboratory Sponsored by: Air

Rhythm and Books: Feel the Beat! 1996 Florida Library Youth Program.

ERIC Educational Resources Information Center

Rupert, Libby, Comp.; And Others

The Florida Library Youth Program is an extension of the Florida Summer Library Program and has emerged in response to a need to provide programs for school-age children at times other than the traditional summer vacation. The theme, "Rhythm and Books--Feel the Beat!," focuses on music and rhythms that abound around children in the…

Think Warm Thoughts: Plan Ahead for Summertime Information Literacy Programs! The College Connection

ERIC Educational Resources Information Center

Kasowitz-Scheer, Abby

2009-01-01

It's winter! While it is frosty outside, one can at least think warm thoughts by starting now to plan ahead for summer information literacy programs. This article is designed to provide some ideas for planning next summer's reading, sleuthing, and research programs. It features a variety of programs organized by academic librarians this past…

Collaboration, Pedagogy, and Media: Short-Term Summer Programs Emphasize Project Based and Social Emotional Learning

ERIC Educational Resources Information Center

Bowden, William R.

2015-01-01

Summer programs that experiment with combining media literacy and social-emotional learning can potentially affect students' academic performance. Based on a six-week program, working with rising eighth grade students in a low-income school district, this program allowed students to work on media projects while trying to develop stronger…

Reading Roundup: Rope a Good Book. Louisiana Summer Reading Program, 1995 Manual.

ERIC Educational Resources Information Center

White, Dorothy, J., Ed.

A manual for the Louisiana Summer Reading Program is presented in 14 sections with a western theme and illustrations. An evaluation form, a 1995 calendar, and a list of audiovisual materials with addresses and prices are also provided. Section 1 discusses promotion, publicity, and programs; and includes sample news releases; program ideas, and…

Breaking down Barriers: A Bridge Program Helps First-Year Biology Students Connect with Faculty

ERIC Educational Resources Information Center

Cooper, Katelyn M.; Ashley, Michael; Brownell, Sara E.

2018-01-01

Summer bridge programs often aim to build social connections for first-year students to ease their transition into college, yet few studies have reported on bridge programs successfully leading to these outcomes. We backward designed a summer bridge program for incoming biology majors to increase the comfort and connections among students and…

Impacts of a Summer Bridge Program in Engineering on Student Retention and Graduation

ERIC Educational Resources Information Center

Cançado, Luciana; Reisel, John R.; Walker, Cindy M.

2018-01-01

A summer bridge program was developed in an engineering program to advance the preparation of incoming freshmen students, particularly with respect to their math course placement. The program was intended to raise the initial math course placement of students who otherwise would begin their engineering studies in courses below Calculus I. One…

Vagal Sensory Innervation of the Gastric Sling Muscle and Antral Wall: Implications for GERD?

PubMed Central

Powley, Terry L.; Gilbert, Jared M.; Baronowsky, Elizabeth A.; Billingsley, Cherie N.; Martin, Felecia N.; Phillips, Robert J.

2012-01-01

Background The gastric sling muscle has not been investigated for possible sensory innervation, in spite of the key roles the structure plays in lower esophageal sphincter (LES) function and gastric physiology. Thus, the present experiment used tracing techniques to label vagal afferents and survey their projections in the lesser curvature. Methods Sprague Dawley rats received injections of dextran biotin into the nodose ganglia. Fourteen days post-injection, animals were euthanized and their stomachs were processed to visualize the vagal afferent innervation. In different cases, neurons, muscle cells, or interstitial cells of Cajal were counterstained. Key Results The sling muscle is innervated throughout its length by vagal afferent intramuscular arrays (IMAs) associated with interstitial cells of Cajal. In addition, the distal antral attachment site of the sling muscle is innervated by a novel vagal afferent terminal specialization, an antral web ending. The muscle wall of the distal antrum is also innervated by conventional IMAs and intraganglionic laminar endings (IGLEs), the two types of mechanoreceptors found throughout stomach smooth muscle. Conclusions & Inferences The innervation of sling muscle by IMAs, putative stretch receptors, suggests that sling sensory feedback may generate vago-vagal or other reflexes with vagal afferent limbs. The restricted distribution of afferent web endings near the antral attachments of sling fibers suggests the possibility of specialized mechanoreceptor functions linking antral and pyloric activity to the operation of the LES. Dysfunctional sling afferents could generate LES motor disturbances, or normative compensatory sensory feedback from the muscle could compromise therapies targeting only effectors. PMID:22925069

The Los Alamos Space Weather Summer School: Career and Research Benefits to Students and Mentors

NASA Astrophysics Data System (ADS)

Cowee, M.; Woodroffe, J. R.

2017-12-01

In 2016 we held the 6th Los Alamos Space Weather Summer School. This 8-week long program is designed for mid-career graduate students in related fields to come to LANL, receive lectures on space physics and space environment topics, and carry out a research project under the mentorship of LANL staff members. We accept typically 6-8 students via competitive admissions to the program, with a strong applicant pool to choose from. This type of summer school program is relatively unique in the space physics community—there are several other summer schools but they are of shorter duration and do not include the mentor-research project aspect which builds a strong one-on-one connection between the summer student and his/her LANL mentor(s). From the LANL perspective, this program was intended to have several benefits including building collaborations between LANL staff and universities and recruitment of potential postdocs. From the student perspective, this program is not only an educational opportunity but a strong networking opportunity and a chance to enhance their professional skills and publication record. Students are permitted to work on projects directly related to their thesis or on projects in areas that are completely new to them. At the end of the summer school, the students also develop their presentation skills by preparing and giving AGU-style presentations on their research projects to the research group. Over the past five years the summer school has increased in popularity, and the feedback from the student participants has been very positive. Alumni of the program have continued collaborations with their mentors, resulting in publications and conference presentations, and three postdoc hires to date.

Hydromania II: Journey of the Oncorhynchus. Summer Science Camp Curriculum 1994.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moura, Joan; Swerin, Rod

The Hydromania II curriculum was written for the third in a series of summer science camp experiences targeting students in grades 4--6 who generally have difficulty accessing supplementary academic programs. The summer science camp in Portland is a collaborative effort between Bonneville Power Administration (BPA), the US Department of Energy (DOE), and the Portland Parks and Recreation Community Schools Program along with various other cooperating businesses and organizations. The curriculum has also been incorporated into other summer programs and has been used by teachers to supplement classroom activities. Camps are designed to make available, affordable learning experiences that are funmore » and motivating to students for the study of science and math. Inner-city, under-represented minorities, rural, and low-income families are particularly encouraged to enroll their children in the program.« less

First Outcomes from the National Summer Learning Study. Brief

ERIC Educational Resources Information Center

McCombs, Jennifer Sloan; Pane, John F.; Augustine, Catherine H.; Schwartz, Heather L.; Martorell, Paco; Zakaras, Laura

2014-01-01

Many students lose knowledge and skills over the long summer break, and research suggests that low-income students fall further behind over the summer than their higher-income peers. Voluntary summer learning programs may provide an opportunity to stem summer learning loss and give struggling students additional learning opportunities. The Wallace…

The Summer Food Service Program and the Ongoing Hunger Crisis in Mississippi.

PubMed

Cobern, Jade A; Shell, Kathryn J; Henderson, Everett R; Beech, Bettina M; Batlivala, Sarosh P

2015-10-01

Food insecurity is simply defined as uncertain access to adequate food. Nearly 50 million Americans, 16 million of whom are children, are food insecure. Mississippi has 21% food insecure citizens, and has the most food insecure county in the nation. Our state's school system's National Breakfast and Lunch Programs help combat food insecurity, but a gap still exists. This gap widens during the summer. In this paper, we describe the Mississippi Summer Food Service Program. While the program has had success in our state, it still faces challenges. Organized action by physicians in Mississippi and the Mississippi State Medical Association could significantly increase participation in these programs that are vital to our state.

An Evaluation of the Cost Effectiveness of Alternative Compensatory Reading Programs, Volume IV: Cost Analysis of Summer Programs. Final Report.

ERIC Educational Resources Information Center

Al-Salam, Nabeel; Flynn, Donald L.

This report describes the results of a study of the cost and cost effectiveness of 27 summer reading programs, carried through as part of a large-scale evaluation of compensatory reading programs. Three other reports describe cost and cost-effectiveness studies of programs during the regular school year. On an instructional-hour basis, the total…

Effects of Different Maturation Systems on Bovine Oocyte Quality, Plasma Membrane Phospholipid Composition and Resistance to Vitrification and Warming.

PubMed

Sprícigo, José F W; Diógenes, Mateus N; Leme, Ligiane O; Guimarães, Ana L; Muterlle, Carolle V; Silva, Bianca Damiani Marques; Solà-Oriol, David; Pivato, Ivo; Silva, Luciano Paulino; Dode, Margot A N

2015-01-01

The objective of this study was to evaluate the effects of different maturation systems on oocyte resistance after vitrification and on the phospholipid profile of the oocyte plasma membrane (PM). Four different maturation systems were tested: 1) in vitro maturation using immature oocytes aspirated from slaughterhouse ovaries (CONT; n = 136); 2) in vitro maturation using immature oocytes obtained by ovum pick-up (OPU) from unstimulated heifers (IMA; n = 433); 3) in vitro maturation using immature oocytes obtained by OPU from stimulated heifers (FSH; n = 444); and 4) in vivo maturation using oocytes obtained from heifers stimulated 24 hours prior by an injection of GnRH (MII; n = 658). A sample of matured oocytes from each fresh group was analyzed by matrix associated laser desorption-ionization (MALDI-TOF) to determine their PM composition. Then, half of the matured oocytes from each group were vitrified/warmed (CONT VIT, IMA VIT, FSH VIT and MII VIT), while the other half were used as fresh controls. Afterwards, the eight groups underwent IVF and IVC, and blastocyst development was assessed at D2, D7 and D8. A chi-square test was used to compare embryo development between the groups. Corresponding phospholipid ion intensity was expressed in arbitrary units, and following principal components analyses (PCA) the data were distributed on a 3D graph. Oocytes obtained from superstimulated animals showed a greater rate of developmental (P<0.05) at D7 (MII = 62.4±17.5% and FSH = 58.8±16.1%) compared to those obtained from unstimulated animals (CONT = 37.9±8.5% and IMA = 50.6±14.4%). However, the maturation system did not affect the resistance of oocytes to vitrification because the blastocyst rate at D7 was similar (P>0.05) for all groups (CONT VIT = 2.8±3.5%, IMA VIT = 2.9±4.0%, FSH VIT = 4.3±7.2% and MII VIT = 3.6±7.2%). MALDI-TOF revealed that oocytes from all maturation groups had similar phospholipid contents, except for 760.6 ([PC (34:1) + H]+), which was more highly expressed in MII compared to FSH (P<0.05). The results suggest that although maturation systems improve embryonic development, they do not change the PM composition nor the resistance of bovine oocytes to vitrification.

Effects of Different Maturation Systems on Bovine Oocyte Quality, Plasma Membrane Phospholipid Composition and Resistance to Vitrification and Warming

PubMed Central

Sprícigo, José F. W.; Diógenes, Mateus N.; Leme, Ligiane O.; Guimarães, Ana L.; Muterlle, Carolle V.; Silva, Bianca Damiani Marques; Solà-Oriol, David; Pivato, Ivo; Silva, Luciano Paulino; Dode, Margot A. N.

2015-01-01

The objective of this study was to evaluate the effects of different maturation systems on oocyte resistance after vitrification and on the phospholipid profile of the oocyte plasma membrane (PM). Four different maturation systems were tested: 1) in vitro maturation using immature oocytes aspirated from slaughterhouse ovaries (CONT; n = 136); 2) in vitro maturation using immature oocytes obtained by ovum pick-up (OPU) from unstimulated heifers (IMA; n = 433); 3) in vitro maturation using immature oocytes obtained by OPU from stimulated heifers (FSH; n = 444); and 4) in vivo maturation using oocytes obtained from heifers stimulated 24 hours prior by an injection of GnRH (MII; n = 658). A sample of matured oocytes from each fresh group was analyzed by matrix associated laser desorption-ionization (MALDI-TOF) to determine their PM composition. Then, half of the matured oocytes from each group were vitrified/warmed (CONT VIT, IMA VIT, FSH VIT and MII VIT), while the other half were used as fresh controls. Afterwards, the eight groups underwent IVF and IVC, and blastocyst development was assessed at D2, D7 and D8. A chi-square test was used to compare embryo development between the groups. Corresponding phospholipid ion intensity was expressed in arbitrary units, and following principal components analyses (PCA) the data were distributed on a 3D graph. Oocytes obtained from superstimulated animals showed a greater rate of developmental (P<0.05) at D7 (MII = 62.4±17.5% and FSH = 58.8±16.1%) compared to those obtained from unstimulated animals (CONT = 37.9±8.5% and IMA = 50.6±14.4%). However, the maturation system did not affect the resistance of oocytes to vitrification because the blastocyst rate at D7 was similar (P>0.05) for all groups (CONT VIT = 2.8±3.5%, IMA VIT = 2.9±4.0%, FSH VIT = 4.3±7.2% and MII VIT = 3.6±7.2%). MALDI-TOF revealed that oocytes from all maturation groups had similar phospholipid contents, except for 760.6 ([PC (34:1) + H]+), which was more highly expressed in MII compared to FSH (P<0.05). The results suggest that although maturation systems improve embryonic development, they do not change the PM composition nor the resistance of bovine oocytes to vitrification. PMID:26107169

Summer Institute for Career Exploration (ICE), 1988. OREA Report.

ERIC Educational Resources Information Center

Berney, Tomi D.; Rosenberg, Jan

In its fourth year, the English-as-a-Second-Language (ESL) component of the Summer Institute for Career Exploration (ICE) program was funded by the federal government's Emergency Immigrant Education Assistance program. Program goals were to help recent immigrants develop English language skills, introduce students to high school requirements and…

Assessing the Impact of a Summer Internship Program for Teachers and Counselors.

ERIC Educational Resources Information Center

Russell, Jill F.; Reiser, Mary Lynn

1999-01-01

Discusses an evaluation of a summer internship program for Omaha, Nebraska, educators that stressed scientific/technical work experience. Results suggest that internship programs can provide a growth experience for teachers and can positively influence students' knowledge, skills, and readiness for the world of work. (MLH)

Summer Sports: A Recreationally Based Program for Building Peer Relations.

ERIC Educational Resources Information Center

Pelham, Jr., William E.; Gnagy, Elizabeth M.

1998-01-01

Describes the Summer Treatment Program (STP), a comprehensive sports training and treatment program for students with Attention Deficit/Hyperactivity Disorder. STP incorporates social-skills training, academic instruction, parent training, and medication evaluation. STP has been shown to be highly successful and its principles can be transferred…

Title I, Part B, Institutionalized Facilities Program, Summer 1982. Annual Evaluation Report.

ERIC Educational Resources Information Center

New York City Board of Education, Brooklyn, NY. Office of Educational Evaluation.

This 1982 summer Title I, Part B, Institutionalized Facilities Program provided supplementary career instruction to 188 students residing in facilities for neglected and delinquent children and youth. This report briefly describes the program, providing information on methodology, physical setting, equipment, and supplies; population and class…

College Bound Program; Summer 1975.

ERIC Educational Resources Information Center

Woloshin, Gerald W.

The principal objectives of the College Bound Summer Program, funded under the Elementary Secondary Education Act Title I, were to improve student's reading and mathematics, increase their ability to do college work, and make the students' transition from junior high to high school easier. Program participants were selected on the basis of either…

Intensive English Programs Newsletter, 1994-1996.

ERIC Educational Resources Information Center

Mcdonald, Andrew, Ed.; Mcdonald, Gina, Ed.

1996-01-01

This document consists of the six issues of this newsletter published during the two-year period summer 1994 to summer 1996. Intended for teachers of intensive English-as-a-Second-Language programs (IEPs), the issue contains the following articles: "The Inviolable Core of Intensive English Programs" (Fredricka L. Stoller); "Report from Baltimore:…

Norco College's Summer Advantage Program: Leading Change to Increase College Readiness

ERIC Educational Resources Information Center

Ring, April

2016-01-01

Norco College, in Riverside County, California, developed the Summer Advantage program in 2012. This program is designed to reduce the number of students placed into precollegiate-level courses and increase first-year retention through participation in academic workshops, intrusive advisement, and college orientation. After four years, the Summer…

Programs at Prices You Can Afford.

ERIC Educational Resources Information Center

Boylan, Patricia

1982-01-01

Describes a set of special programs for adolescents which have been sponsored by the Smithtown, New York, Public Library. The 12 programs outlined (one for each month of the year) include a summer jobs seminar, a swap shop, a music festival, a game tournament, and a summer sailing presentation. (JL)

Project SAIL: A Summer Program Brings History Alive for Students.

ERIC Educational Resources Information Center

Hollingsworth, Patricia

2001-01-01

This project describes Project SAIL (Schools for Active Interdisciplinary Learning), a federally funded project providing in-depth staff development during a 3-week summer program for teachers, parents, and their gifted/talented economically disadvantaged students. The program theme, "Searching for Patterns in History," has been used with students…

Teen Summer Reading Program, 1999. Read around the World.

ERIC Educational Resources Information Center

Virginia State Library, Richmond.

This guide for the 1999 Virginia teen summer reading program for public libraries, "Read around the World," includes the following chapters: (1) "Reading and Teens," including serving the underserved, tips for teens, and a recipe for choosing a book to read for fun; (2) "Programming and Teens," including "The Why…

HBCU Summer Undergraduate Training Program in Prostate Cancer Research

DTIC Science & Technology

2011-08-01

in Prostate Cancer Research INTRODUCTION: The goal of this award was to provide prostate cancer (CaP) research summer internships to the...Selection Process: USU/CPDR summer internship program announcements for 2008, 2009 and 2010 were made by Dr. Deepak Kumar (Partnering PI) at the...Department of Anatomy, Physiology and Genetics and Department of Microbiology and Immunology actively participated in training of UDC students under the

Effective and Promising Summer Learning Programs and Approaches for Economically-Disadvantaged Children and Youth: A White Paper for the Wallace Foundation

ERIC Educational Resources Information Center

Terzian, Mary; Moore, Kristin Anderson; Hamilton, Kathleen

2009-01-01

This White Paper summarizes findings from an extensive literature review that was conducted to identify the most promising models and approaches for meeting the needs of low-income children, youth, and families during the summer months. Special attention is paid to summer learning programs that serve diverse, urban low-income children and youth.…

The Effects of a Summer Reading Program Using Simultaneous Multisensory Instruction of Language Arts on Reading Proficiency

ERIC Educational Resources Information Center

Magpuri-Lavell, Theresa; Paige, David; Williams, Rosemary; Akins, Kristia; Cameron, Molly

2014-01-01

The present study examined the impact of the Simultaneous Multisensory Institute for Language Arts (SMILA) approach on the reading proficiency of 39 students between the ages of 7-11 participating in a summer reading program. The summer reading clinic draws students from the surrounding community which is located in a large urban district in the…

Hunger Doesn't Take a Vacation: A Status Report on the Summer Food Service Program for Children. Third Edition.

ERIC Educational Resources Information Center

Food Research and Action Center, Washington, DC.

This report provides an evaluation of the efforts each state and the District of Columbia are making to provide nutritious summer meals to children of low-income families. The evolution of the Summer Food Service Program for Children (SFSP), created by Congress in 1968 to provide funds for eligible sponsoring organizations to serve meals to…

Summer Course Promotes Polymer Chemistry for Small Colleges.

ERIC Educational Resources Information Center

Stinson, Stephen

1989-01-01

Describes a three-week summer program teaching selected chemistry faculty how to incorporate polymer chemistry into chemistry courses. In addition to lectures, the program conducted many experiments and provided a trip to industry laboratories. (YP)

MCTP Summer Research Internship Program. Research Presentation Day: Experience Mathematics and Science in the Real World

NASA Technical Reports Server (NTRS)

1996-01-01

This paper presents the summaries of the MCTP Summer Research Internship Program. Technological areas discussed include: Mathematical curriculum development for real world problems; Rain effects on air-water gas exchange; multi-ring impact basins on mars; developing an interactive multimedia educational cd-rom on remote sensing; a pilot of an activity for for the globe program; fossils in maryland; developing children's programming for the american horticultural society at river farm; children's learning, educational programs of the national park service; a study of climate and student satisfaction in two summer programs for disadvantaged students interested in careers in mathematics and science; the maryland governor's academy, integrating technology into the classroom; stream sampling with the maryland biological stream survey (MBSS); the imaging system inspection software technology, the preparation and detection of nominal and faulted steel ingots; event-based science, the development of real-world science units; correlation between anxiety and past experiences; environmental education through summer nature camp; enhancing learning opportunities at the Salisbury zoo; plant growth experiment, a module for the middle school classroom; the effects of proxisome proliferators in Japanese medaka embryos; development of a chapter on birth control and contraceptive methodologies as part of an interactive computer-based education module on hiv and aids; excretion of gentamicin in toadfish and goldfish; the renaissance summer program; and Are field trips important to the regional math science center?

NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program, 1985. [Space Stations and Their Environments

NASA Technical Reports Server (NTRS)

Chilton, R. G. (Editor); Williams, C. E. (Editor)

1986-01-01

The 1985 NASA/ASEE Summer Faculty Fellowship Research Program was conducted by Texas A&M University and the Johnson Space Center. The ten week program was operated under the auspices of the American Society for Engineering Education (ASEE). The faculty fellows spent the time at JSC engaged in research projects commensurate with their interests and background and worked in collaboration with NASA/JSC colleagues. This document is a compilation of the final reports of their research during the summer of 1985.

A model summer program for handicapped college students

NASA Technical Reports Server (NTRS)

Nissen, Anne B.

1989-01-01

During the summer of 1988, the Goddard Space Flight Center was the site of a new NASA project called A Model Summer Program for Handicapped College Students that was directed by Gallaudet University. The project's aim was to identify eight severely physically disabled college students (four from Gallaudet University and four from local historically black colleges and universities (HBCU's)) majoring in technical fields and to assign them technical projects related to aerospace which they would complete under the guidance of mentors who were full time employees of Goddard. A description of the program is presented.

United States Air Force Summer Research Program -- 1993. Volume 16. Arnold Engineering Development Center. Frank J. Seiler Research Laboratory. Wilford Hall Medical Center

DTIC Science & Technology

1993-12-01

A I 7f t UNITED STATE AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 16 ARNOLD ENGINEERING DEVELOPMENT CENTER...FRANK J. SELLER RESEARCH LABORATORY WILFORD HALL MEDICAL CENTER RESEARCH & DEVELOPMENT LABORATORIES 5800 Uplander Way Culver City, CA 90230-6608...National Rd. Vol-Page No: 15-44 Dist Tecumseh High School 8.4 New Carlisle, OH 45344-0000 Barber, Jason Laboratory: AL/CF 1000 10th St. Vol-Page No

Development and evaluation of a learner-centered educational summer camp program on soft skills for baccalaureate nursing students.

PubMed

Lau, Ying; Wang, Wenru

2014-01-01

The objectives were to develop a learner-centered educational camp program for nursing students and to evaluate 4 areas of soft skills, communication ability, clinical interaction, interpersonal relationships, and social problem solving, before and after the program. The results showed that the summer camp program was effective in improving nursing students' soft skills.

A Bridge to a Smart Start: A Case Study of Northampton Community College's Summer Bridge Program

ERIC Educational Resources Information Center

Sparrow, Michael J.

2017-01-01

This study sought to understand how and why Northampton Community College's Summer Bridge program--The Smart Start program--is highly successful at helping "at-risk" students transition to college-level work. For ten years, the Smart Start program has helped more than 150 incoming students acclimate to college, persist, and graduate…

"I Actually Contributed to Their Research": The Influence of an Abbreviated Summer Apprenticeship Program in Science and Engineering for Diverse High-School Learners

ERIC Educational Resources Information Center

Burgin, Stephen R.; McConnell, William J.; Flowers, Alonzo M., III

2015-01-01

This study describes an investigation of a research apprenticeship program that we developed for diverse high-school students often underrepresented in similar programs and in science, technology, engineering, and math (STEM) professions. Through the apprenticeship program, students spent 2 weeks in the summer engaged in biofuels-related research…

Getting Ready for College: An Implementation and Early Impacts Study of Eight Texas Developmental Summer Bridge Programs. NCPR Brief

ERIC Educational Resources Information Center

Wathington, Heather D.; Barnett, Elisabeth A.; Weissman, Evan; Teres, Jedediah; Pretlow, Joshua; Nakanishi, Aki

2011-01-01

In 2009, the National Center for Postsecondary Research (NCPR) launched an evaluation of eight developmental summer bridge programs in Texas to assess whether these programs reduce the need for developmental coursework and improve student outcomes in college. The evaluation uses an experimental design to measure the effects of these programs on…

Vacation Study Abroad, 1994/95. The Complete Guide to Summer and Short-Term Study.

ERIC Educational Resources Information Center

Steen, Sara J., Ed.

This book describes over 2,100 academic programs sponsored by U.S. and foreign universities, language schools, and a wide variety of other organizations for summer and short-term study abroad programs. Entries are based on a 1993 survey. While most programs listed are available to undergraduates, many programs are also open to precollege students,…

Evaluation of the Nursing Program at Caldwell Community College and Technical Institute--Summer, 1983.

ERIC Educational Resources Information Center

Pipes, V. David

In summer 1983, an evaluation of the nursing program at Caldwell Community College and Technical Institute was conducted to determine whether program objectives were being met, to measure program success, and to identify areas needing improvement. Surveys were sent to 19 early (pre-1978) and 47 recent Licensed Practical Nurse (LPN) graduates; 17…

A New Model for a Multi-Disciplinary Engineering Summer Research Program for High School Seniors: Program Overview, Effectiveness, and Outcomes

ERIC Educational Resources Information Center

Kittur, H.; Shaw, L.; Herrera, W.

2017-01-01

The High School Summer Research Program (HSSRP) is a rigorous eight-week research experience that challenges high school students to a novel scientific question in an engineering laboratory at the Henry Samueli School of Engineering and Applied Science (HSSEAS) at the University of California, Los Angeles (UCLA). The program collates highly…

Georgetown University and Hampton University Prostate Cancer Undergraduate Fellowship Program

DTIC Science & Technology

2014-09-01

HU-GU Fellow Summer 2013 HU Class of 2015 Kimiko Krieger HU-GU Fellow Summer 2013 HU Class of 2014 Nathan Wilson HU-GU Fellow Summer 2013 HU Class...Tiffany Lumpkin HU-GU Fellow Summer 2010 Class of 2012; Johns Hopkins MS Biotechnology 2013 Zerin Scales HU-GU Fellow Summer 2010 Class of 2013

The I Have a Dream/Coro Summer Work Partnership Project: Pilot Training Program. Initial Assessment.

ERIC Educational Resources Information Center

White, Emily; And Others

In the summer of 1991, 24 students, members of an I Have a Dream (IHAD) program, took part in a pilot program to introduce them to the work force through internships augmented by a training program. The Coro Foundation was contacted by IHAD to run the training program, which was adapted to the needs of disadvantaged students entering 10th grade.…

The Impact of a Campus-Based 4-H Summer Conference Program on Youth Thriving

ERIC Educational Resources Information Center

Arnold, Mary E.; Davis, Jamie M.; Lundeberg, Roberta

2017-01-01

In 2014 the Oregon 4-H program adopted a new program model to describe and evaluate the impact of 4-H on youths. The model is based on promoting thriving in young people, with an emphasis on high program quality. This article discusses the impact on thriving in 378 youth participants of the 4-H Summer Conference (4-HSC) program. The results of the…

The 2013 Summer Undergraduate Research Internship Program at the Pisgah Astronomical Research Institute

NASA Astrophysics Data System (ADS)

Castelaz, Michael W.; Cline, J. D.; Whitworth, C.; Clavier, D.; Barker, T.

2014-01-01

Pisgah Astronomical Research Institute (PARI) offers summer undergraduate research internships. PARI has received support for the internships from the EMC Corporation, private donations, private foundations, and through a collaboration with the Pisgah Astronomical Research and Education Center of the University of North Carolina - Asheville. The internship program began in 2001 with 4 students. This year 10 funded students participated. Mentors for the interns include PARI’s Directors of Science, Education, and Information Technology and visiting faculty who are members of the PARI Research Faculty Affiliate program. Students work with mentors on radio and optical astronomy research, electrical engineering for robotic control of instruments, software development for instrument control and and science education by developing curricula and multimedia and teaching high school students in summer programs at PARI. At the end of the summer interns write a paper about their research which is published in the PARI Summer Student Proceedings. Students are encouraged to present their research at AAS Meetings. We will present a summary of specific research conducted by the students with their mentors.

Protecting Human Health in a Changing Environment: 2018 Summer Enrichment Program

EPA Pesticide Factsheets

The U.S. Environmental Protection Agency (EPA) in Research Triangle Park, NC is offering a free 1-week Summer Enrichment Program to educate students about how the Agency protects human health and the environment.

Perceptions of the Value of Extended Service in Horticulture.

ERIC Educational Resources Information Center

Watkins, Larae; Miller, Larry E.

1983-01-01

This study suggests the need for several improvements in the summer vocational horticulture education programs. Knowledge of the summer program, its aims, and the teacher's responsibilities appears to be lacking in the groups studied. (SSH)

Enhancing the Transition to Kindergarten: A Randomized Trial to Test the Efficacy of the “Stars” Summer Kindergarten Orientation Program

PubMed Central

Berlin, Lisa J.; Dunning, Rebecca D.; Dodge, Kenneth A.

2010-01-01

This randomized trial tested the efficacy of an intensive, four-week summer program designed to enhance low-income children's transition to kindergarten (n's = 60 program children, 40 controls). Administered in four public schools, the program focused on social competence, pre-literacy and pre-numeracy skills, school routines, and parental involvement. Hierarchical linear modeling indicated that the program significantly improved teachers’ ratings of (a) the transition to the social aspect of kindergarten for girls (but not boys); and (b) the transition to kindergarten routines for the subgroup of children who had the same teacher for kindergarten as for the summer program. Findings are discussed in terms of practices and policies for supporting children's transition to school. PMID:21969767

Downscaling Surface Temperature Image with TsHARP

USDA-ARS?s Scientific Manuscript database

Daily evapotranspiration (ET) maps would significantly improve assessing crop water requirements, especially in the Texas High Plains (THP) where the supply of irrigation water is limited. Evapotranspireation maps derived from satellite data with daily coverage such as MODIS (Moderate Resolution Ima...

2010 Summer Transportation Institute

DOT National Transportation Integrated Search

2012-09-01

The Summer Transportation Institute (STI) hosted by the Western Transportation Institute at Montana : State University serves to attract high school students to participate in an innovative summer : educational program in transportation. The STI aims...

2010 Summer Transportation Institute

DOT National Transportation Integrated Search

2010-09-01

The Summer Transportation Institute (STI) hosted by the Western Transportation Institute at Montana : State University serves to attract high school students to participate in an innovative summer : educational program in transportation. The STI aims...

A RESOURCE GUIDE FOR THIRD GRADE SUMMER SCHOOL ACCELERATION CLASSES. THE AMERICAN INDIAN--A STUDY OF LIFE IN A PRIMITIVE CULTURE.

ERIC Educational Resources Information Center

TRAINOR, LOIS M.; AND OTHERS

THE SUMMER PROGRAM IS PART OF A PROGRAM IN WHICH SECOND-GRADE GIFTED STUDENTS ARE GIVEN INSTRUCTION IN BASIC THIRD-GRADE SKILLS IN LANGUAGE AND ARITHMETIC DURING THE SPRING SEMESTER. THE SUMMER SESSION PROVIDES FOR IMPROVEMENT IN THESE SKILLS ON AN INDIVIDUAL BASIS AND FOR ENRICHMENT IN SOCIAL STUDIES. THE UNIT ON THE AMERICAN INDIAN DESCRIBED IS…

What Works for Summer Learning Programs for Low-Income Children and Youth: Preliminary Lessons from Experimental Evaluations of Social Interventions. Fact Sheet. Publication #2009-41

ERIC Educational Resources Information Center

Terzian, Mary; Moore, Kristin A.

2009-01-01

Children and youth who reside in economically disadvantaged households and in low-resource, urban neighborhoods are more likely to lose ground in math and reading over the summer than their higher-income peers. Although summer learning programs are a promising strategy for narrowing this achievement gap, surveys indicate that only 25 to 36 percent…

Quality of Subjective Experience in a Summer Science Program for Academically Talented Adolescents.

ERIC Educational Resources Information Center

Tuss, Paul

This study utilized the flow theory of intrinsic motivation to evaluate the subjective experience of 78 academically talented high school sophomores participating in an 8-day summer research apprenticeship program in materials and nuclear science. The program involved morning lectures on such topics as physics of electromagnetic radiation, energy…

MADD About Good Books.

ERIC Educational Resources Information Center

Parker, Marilyn K.

The MADD (music, art, dance, and drama) About Good Books program is a summer Arts Impact program for students in grades 3-6 offered by the Columbus, Ohio Public Schools. Conducted by two literature teachers, the 1975 summer program got under way as the children set the stage by constructing a large tree, for reading and chatting under, and…

Measuring the Success of a Summer Reading Program: A Five-Year Study

ERIC Educational Resources Information Center

Liljequist, Laura; Stone, Staci

2009-01-01

Students were surveyed about a first-year summer reading program (SRP) at Murray State University, a regional, comprehensive university, for five consecutive years. Data are presented on how well the program met five stated goals: (a) providing a common academic experience for incoming first-year students, (b) introducing students to intellectual…

1984 Summer Scholars Participants. A Follow Up.

ERIC Educational Resources Information Center

Mares, Kenneth R.; And Others

A followup study was conducted to assess the impact of two 1984 Summer Scholars Programs at the University of Missouri, Kansas City, School of Medicine, which sponsors a combined bachelor's degree and doctor of medicine (M.D.) program. The university, in cooperation with area hospitals, implemented a 4-week program to identify and motivate…

Getting Ready for College: An Implementation and Early Impacts Study of Eight Texas Developmental Summer Bridge Programs

ERIC Educational Resources Information Center

Wathington, Heather D.; Barnett, Elisabeth A.; Weissman, Evan; Teres, Jedediah; Pretlow, Joshua; Nakanishi, Aki

2011-01-01

In 2007, the Texas Higher Education Coordinating Board (THECB) funded 22 colleges to establish developmental summer bridge programs. Aimed at providing an alternative to traditional developmental education, these programs involve intensive remedial instruction in math, reading, and/or writing and college preparation content for students entering…

A Program Evaluation of a Summer Research Training Institute for American Indian and Alaska Native Health Professionals

ERIC Educational Resources Information Center

Zaback, Tosha; Becker, Thomas M.; Dignan, Mark B.; Lambert, William E.

2010-01-01

In this article, the authors describe a unique summer program to train American Indian/Alaska Native (AI/AN) health professionals in a variety of health research-related skills, including epidemiology, data management, statistical analysis, program evaluation, cost-benefit analysis, community-based participatory research, grant writing, and…

An Evaluation of Parent Aide Programs.

ERIC Educational Resources Information Center

Andrews, Mary P.; Swanson, Jane F.

A descriptive-comparative study was designed to document the service delivery functions and impacts of three different parent-aide programs ongoing in Michigan. The study took place over the period of summer 1978 to summer 1979. The programs involved in the study were the Genesee County Department of Social Services' Volunteer Services Parent-Aide…

Summer Bilingual Program, 1988. OREA Report.

ERIC Educational Resources Information Center

Berney, Tomi D.; Rosenberg, Jan

The 1988 Summer Bilingual Program served 1,171 ninth- through twelfth-graders with limited English proficiency (LEP) at 10 New York City sites. Designed especially for the substantial number of LEP students who were overage for their grade, the program offered 14 English as a Second Language (ESL) and 17 bilingual content area classes in science,…

Make Waves: Read! 1998 Summer Library Program Manual. Bulletin No. 98107.

ERIC Educational Resources Information Center

Roeber, Jane A., Ed.

This manual is designed to help individual libraries in Wisconsin plan and implement their summer library programs. The manual is divided into six sections. Section 1 covers planning and promoting programs, and includes reproducible promotional materials, sample letters to parents, and sample media materials. Section 2 provides decorating and…

77 FR 31339 - Board of Visitors, United States Military Academy (USMA)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

... DEPARTMENT OF DEFENSE Department of the Army Board of Visitors, United States Military Academy... States Military Academy Board of Visitors. 2. Date: Thursday, June 14, 2012. 3. Time: 12:00 p.m.-2:30 p.m... and Military Programs, to include Summer Training; the Academic Program, Summer Term Academic Program...

An Alternative School Teacher Education Program. Teacher Education Forum; Volume 3, Number 7.

ERIC Educational Resources Information Center

Barr, Robert D.

The Alternative School Teacher Education Program, cooperatively developed by participating public schools and Indiana University, is a field-based masters degree program designed for completion in one calendar year. Students spend two summers on campus pursuing graduate course work. During the academic year between these summers, students earn…

Building Better Bridges into STEM: A Synthesis of 25 Years of Literature on STEM Summer Bridge Programs

ERIC Educational Resources Information Center

Ashley, Michael; Cooper, Katelyn M.; Cala, Jacqueline M.; Brownell, Sara E.

2017-01-01

Summer bridge programs are designed to help transition students into the college learning environment. Increasingly, bridge programs are being developed in science, technology, engineering, and mathematics (STEM) disciplines because of the rigorous content and lower student persistence in college STEM compared with other disciplines. However, to…

"Far Horizons" -- Near-space Exploration At The Adler Planetarium

NASA Astrophysics Data System (ADS)

Hammergren, Mark; Gyuk, G.; Friedman, R. B.

2011-01-01

Over the past four years, the Adler Planetarium has developed a diverse suite of educational activities involving hands-on scientific exploration via our "Far Horizons" high-altitude ballooning program. These efforts largely have been focused on increasing excitement and motivation for learning outside of school time, and include middle school summer camps, a high school summer program (the Astro-Science Workshop), school-year internships for high school students, summer internships for undergraduates, a NSF-funded graduate fellowship, and an active public volunteer program. In 2010, our programs were dedicated to the memory of renowned Chicago adventurer and explorer Steve Fossett. In 2011, in continued tribute to Steve Fossett, we further expand our out-of-school time programs with a summer workshop designed to enable high school teachers to form and advise student high-altitude ballooning clubs. This model program will be developed as one element of our ongoing partnership with the Air Force Academy High School in Chicago. This material is based in part upon work supported by the National Science Foundation under Grant No. 0525995.

Successes and Challenges in the SAGE (Summer of Applied Geophysical Experience) REU Program

NASA Astrophysics Data System (ADS)

Braile, L. W.; Baldridge, W. S.; Pellerin, L.; Ferguson, J. F.; Bedrosian, P.; Biehler, S.; Jiracek, G. R.; Snelson, C. M.; Kelley, S.; McPhee, D.

2014-12-01

The SAGE program was initiated in 1983 to provide an applied geophysics research and education experience for students. Since 1983, 820 students have completed the SAGE summer program. Beginning in 1992, with funding from the NSF, SAGE has included an REU (Research Experience for Undergraduates) experience for selected undergraduate students from U.S. colleges and universities. Since 1992, 380 undergraduate REU students have completed the SAGE program. The four week, intensive, summer program is based in Santa Fe, New Mexico, and involves students in learning geophysical theory and applications; collection of geophysical field data in the northern Rio Grande Rift area; data processing, modeling and interpretation; and presentation (oral and written) of results of each student's research results. Students (undergraduates, graduates and professionals) and faculty are together on a school campus for the summer program. Successful strategies (developed over the years) of the program include teamwork experience, mentoring of REUs (by faculty and more senior students), cultural interchange due to students from many campuses across the U.S. and international graduate students, including industry visitors who work with the students and provide networking, a capstone experience of the summer program that includes all students making a "professional-meeting" style presentation of their research and submitting a written report, a follow-up workshop for the REU students to enhance and broaden their experience, and providing professional development for the REUs through oral or poster presentations and attendance at a professional meeting. Program challenges include obtaining funding from multiple sources; significant time investment in program management, reporting, and maintaining contact with our many funding sources and industry affiliates; and, despite significant efforts, limited success in recruiting racial and ethnic minority students to the program.

NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program 1992

NASA Technical Reports Server (NTRS)

Spencer, John H. (Compiler)

1992-01-01

Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives of the program are (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participants' institutions; and (4) to contribute to the research objectives of the NASA center.

Booktalking: Avoiding Summer Drift

ERIC Educational Resources Information Center

Whittingham, Jeff; Rickman, Wendy A.

2015-01-01

Summer drift, otherwise known as loss of reading comprehension skills or reading achievement, has been a well-known and well-documented phenomenon of public education for decades. Studies from the late twentieth century to the present have demonstrated a slowdown in summer drift attributed to specific summer reading programs addressing motivation…

2010 Montana Summer Transportation Institute.

DOT National Transportation Integrated Search

2010-09-01

The Summer Transportation Institute (STI) hosted by the Western Transportation Institute at Montana : State University serves to attract high school students to participate in an innovative summer : educational program in transportation. The STI aims...

A Summer Doorway to Science Careers.

ERIC Educational Resources Information Center

Michalek, Arthur M.; And Others

1986-01-01

Provides an overview of the Roswell Park Memorial Institute Summer Science Program for high ability students with strong scientific and mathematical backgrounds. Discusses the participants perceptions of the benefits of this program and reports data related to participants' college majors. (ML)

A 1966 SUMMER PROGRAM FOR CHILDREN WITH PHYSICAL, MULTIPLE AND MENTAL HANDICAPS, JUNE 22, 1966 - AUGUST 17, 1966. PROGRAM EVALUATION.

ERIC Educational Resources Information Center

Milwaukee Public Schools, WI.

THIS SUMMER PROGRAM FOR HANDICAPPED CHILDREN WAS DESIGNED TO MEET THE SPECIAL NEEDS OF THESE CHILDREN FOR SOCIALIZATION AND BETTER USE OF LEISURE TIME AND TO PROVIDE DATA WHICH WOULD ENABLE THE DIVISION OF MUNICIPAL RECREATION AND ADULT EDUCATION OF THE MILWAUKEE PUBLIC SCHOOLS TO PLAN FUTURE PROGRAMS. BOTH THE MENTALLY HANDICAPPED CHILDREN'S…

Program Evaluation of Growin' to Win: A Latchkey and Summer Program for At-Risk Youth.

ERIC Educational Resources Information Center

James, William H.; And Others

This document presents an evaluation of the effectiveness of the Growin' to Win Project, an after-school and summer program targeted at elementary and middle school aged youth at high risk of substance abuse and gang involvement. Growin' to Win is an expansion of a model latchkey program piloted at two Tacoma (Washington) schools in 1990. The…

2011 Montana Summer Transportation Institute.

DOT National Transportation Integrated Search

2011-09-01

The Summer Transportation Institute (STI) hosted by the Western Transportation Institute at Montana State University serves to attract high school students to participate in an innovative summer educational program in transportation. The STI aims to ...

Center for Computing Research Summer Research Proceedings 2015.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, Andrew Michael; Parks, Michael L.

2015-12-18

The Center for Computing Research (CCR) at Sandia National Laboratories organizes a summer student program each summer, in coordination with the Computer Science Research Institute (CSRI) and Cyber Engineering Research Institute (CERI).

Finding Funds to Move Summer Learning Forward

ERIC Educational Resources Information Center

Seidel, Bob

2015-01-01

Summer learning loss creates a permanent drag on the US education system. With the generous support of the Charles Stewart Mott Foundation, the National Summer Learning Association (NSLA) developed "Moving Summer Learning Forward: A Strategic Roadmap for Funding in Tough Times" to provide out-of-school time programs, school districts,…

The 1993 NASA-ODU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

NASA Technical Reports Server (NTRS)

Tiwari, Surendra N. (Compiler); Young, Deborah B. (Compiler)

1993-01-01

Since 1964, the National Aeronautics and Space Administration has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives are: to further the professional knowledge of qualified engineering and science faculty members; to stimulate and exchange ideas between participants and NASA; to enrich and refresh the research and teaching activities of participants' institutions; and to contribute to the research objectives of the NASA center.

1994 NASA-HU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

NASA Technical Reports Server (NTRS)

Spencer, John H. (Compiler); Young, Deborah B. (Compiler)

1994-01-01

Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4) To contribute to the research objectives of the NASA center.

Camp NERF: methods of a theory-based nutrition education recreation and fitness program aimed at preventing unhealthy weight gain in underserved elementary children during summer months.

PubMed

Hopkins, Laura C; Fristad, Mary; Goodway, Jacqueline D; Eneli, Ihuoma; Holloman, Chris; Kennel, Julie A; Melnyk, Bernadette; Gunther, Carolyn

2016-10-26

The number of obese children in the US remains high, which is problematic due to the mental, physical, and academic effects of obesity on child health. Data indicate that school-age children, particularly underserved children, experience unhealthy gains in BMI at a rate nearly twice as fast during the summer months. Few efforts have been directed at implementing evidence-based programming to prevent excess weight gain during the summer recess. Camp NERF is an 8-week, multi-component (nutrition, physical activity, and mental health), theory-based program for underserved school-age children in grades Kindergarten - 5th coupled with the USDA Summer Food Service Program. Twelve eligible elementary school sites will be randomized to one of the three programming groups: 1) Active Control (non-nutrition, physical activity, or mental health); 2) Standard Care (nutrition and physical activity); or 3) Enhanced Care (nutrition, physical activity, and mental health) programming. Anthropometric, behavioral, and psychosocial data will be collected from child-caregiver dyads pre- and post-intervention. Site-specific characteristics and process evaluation measures will also be collected. This is the first, evidence-based intervention to address the issue of weight gain during the summer months among underserved, school-aged children. Results from this study will provide researchers, practitioners, and public health professionals with insight on evidence-based programming to aid in childhood obesity prevention during this particular window of risk. NCT02908230/09-19-2016.

The Summer Undergraduate Research Internship Program at the Pisgah Astronomical Research Institute

NASA Astrophysics Data System (ADS)

Cline, J. Donald; Castelaz, M.; Whitworth, C.; Clavier, D.; Owen, L.; Barker, T.

2012-01-01

Pisgah Astronomical Research Institute (PARI) offers summer undergraduate research internships. PARI has received support for the internships from the NC Space Grant Consortium, NSF awards for public science education, private donations, private foundations, and through a collaboration with the Pisgah Astronomical Research and Education Center of the University of North Carolina - Asheville. The internship program began in 2001 with 4 students. This year 7 funded students participated in 2011. Mentors for the interns include PARI's Science, Education, and Information Technology Directors and visiting faculty who are members of the PARI Research Affiliate Faculty program. Students work with mentors on radio and optical astronomy research, electrical engineering for robotic control of instruments, software development for instrument control and software for citizen science projects, and science education by developing curricula and multimedia and teaching high school students in summer programs at PARI. At the end of the summer interns write a paper about their research which is published in the PARI Summer Student Proceedings. Several of the students have presented their results at AAS Meetings. We will present a summary of specific research conducted by the students with their mentors, the logistics for hosting the PARI undergraduate internship program, and plans for growth based on the impact of an NSF supported renovation to the Research Building on the PARI campus.

The Summer Undergraduate Research Internship Program at the Pisgah Astronomical Research Institute

NASA Astrophysics Data System (ADS)

Castelaz, Michael W.; Cline, J.; Whitworth, C.; Clavier, D.

2011-01-01

Pisgah Astronomical Research Institute (PARI) offers summer undergraduate research internships. PARI has received support for the internships from the NC Space Grant Consortium, NSF awards for public science education, private donations, private foundations, and through a collaboration with the Pisgah Astronomical Research and Education Center of the University of North Carolina - Asheville. The internship program began in 2001 with 4 students. This year 9 funded students participated in 2010. Mentors for the interns include PARI's Directors of Science, Education, and Information Technology and visiting faculty who are members of the PARI Research Affiliate Faculty program. Students work with mentors on radio and optical astronomy research, electrical engineering for robotic control of instruments, software development for instrument control and applets for citizen science projects, and science education by developing curricula and multimedia and teaching high school students in summer programs at PARI. At the end of the summer interns write a paper about their research which is published in the PARI Summer Student Proceedings. Several of the students have presented their results at AAS Meetings. We will present a summary of specific research conducted by the students with their mentors, the logistics for hosting the PARI undergraduate internship program, and plans for growth based on the impact of an NSF supported renovation to the Research Building on the PARI campus.

The Effects of the Elevate Math Summer Program on Math Achievement and Algebra Readiness

ERIC Educational Resources Information Center

Snipes, Jason; Huang, Chun-Wei; Jaquet, Karina; Finkelstein, Neal

2016-01-01

To raise math success rates in middle school, many schools and districts have implemented summer math programs designed to improve student preparation for algebra content in grade 8. However, little is known about the effectiveness of these programs. While students who participate typically experience learning gains, there is little rigorous…

The Impact of Oakland Freedom School's Summer Youth Program on the Psychosocial Development of African American Youth

ERIC Educational Resources Information Center

Bethea, Sharon L.

2012-01-01

The present investigation considers the program outcomes of one community youth project, Leadership Excellence Inc., Oakland Freedom Schools. Oakland Freedom Schools are culturally relevant 6-week summer Language Arts enrichment programs for primarily inner-city African American youth aged 5 to 14 years. In this study, 79 African American youth…

State Plan for Summer Food Service Program--1978. School Food Service.

ERIC Educational Resources Information Center

Kansas State Dept. of Education, Topeka.

This plan presents required state and federal information for the administration and procedures for the 1978 Summer Food Service Program in Kansas. In 1977, the program increased its availability to low income children through a 41 percent increase of the sponsors and a 54 percent increase of sites where the children were served breakfast, lunch,…

Tackling the Law and Raising the Issues: Summer Program Prepares Students.

ERIC Educational Resources Information Center

Bowannie, Mary

2003-01-01

An intensive 8-week summer program in New Mexico prepares American Indian and Alaska Native students to succeed in law school, focusing on law research, analysis, and writing. Two program graduates who went on to complete law school discuss the complexities of federal Indian law and the Native lawyers' responsibility to their communities--an…

Impact of Online Summer Mathematics Bridge Program on Placement Scores and Pass Rates

ERIC Educational Resources Information Center

Frost, Jodi L.; Dreher, J. P.

2017-01-01

An online four-week summer mathematics bridge program was implemented at a Midwest university with historically low pass rates in College Algebra and Remedial Mathematics. Students who completed the four week program significantly increased their mathematics placement exam scores. These students also had a higher pass rate in their initial college…

Getting Ready for College: An Implementation and Early Impacts Study of Eight Texas Developmental Summer Bridge Programs. Executive Summary

ERIC Educational Resources Information Center

Wathington, Heather D.; Barnett, Elisabeth A.; Weissman, Evan; Teres, Jedediah; Pretlow, Joshua; Nakanishi, Aki

2011-01-01

In 2007, the Texas Higher Education Coordinating Board (THECB) funded 22 colleges to establish developmental summer bridge programs. Aimed at providing an alternative to traditional developmental education, these programs involve intensive remedial instruction in math, reading, and/or writing and college preparation content for students entering…

Teaching Students to Write across a Border: A Writing Curriculum for Inner-City College Access Programs

ERIC Educational Resources Information Center

Dobbs, Jennifer Kwon

2012-01-01

This article explores the development of the Summer Tools, Information, Motivation, and Education (SummerTIME) Writing Program, the only program of its kind in Los Angeles that conducts self-assessment. The author describes the geographical and political boundaries separating inner-city Los Angeles high school graduates from higher education,…

A Controlled Evaluation of Behavioral Treatment with Children with ADHD Attending a Summer Treatment Program

ERIC Educational Resources Information Center

Coles, Erika K.; Pelham, William E.; Gnagy, Elizabeth M.; Burrows-MacLean, Lisa; Fabiano, Gregory A; Chacko, Anil; Wymbs, Brian T.; Tresco, Katy E.; Walker, Kathryn S.; Robb, Jessica A.

2005-01-01

Individual treatment response to behavior modification was examined in the context of a summer treatment program. Four children ages 11 to 12 and diagnosed with attention-deficit/hyperactivity disorder were examined in a BABAB design in which a comprehensive behavioral program was utilized and withdrawn across an 8-week period. Dependent measures…

Seeking Summer Support: What Application Essays Reveal about Applicants to a Mentorship Program for Talented Teens

ERIC Educational Resources Information Center

Savino, Jennifer Ann

2012-01-01

Summer programs help many talented, motivated students further develop their talents, realize their interests, and actualize their goals. Extensive data are available that reveal the benefits of these programs on students' achievement, efficacy, and adjustment; however, little data exist that reveal--in students' own words--the…

Course Selections and Career Plans of Black Participants in a Summer Intervention Program for Minority Students.

ERIC Educational Resources Information Center

Watts, Velma Gibson; And Others

1989-01-01

Data were gathered from participants in a summer program at the Bowman Gray School of Medicine of Wake Forest University. This program was designed for academically talented minority students to promote their awareness of medicine as a potential career and to strengthen their science and mathematics backgrounds. (Author/MLW)

Summer Bilingual Program, 1989. OREA Report.

ERIC Educational Resources Information Center

Berney, Tomi D.; Simon, Monique S.

The 1989 Summer Bilingual Program, funded for its third year by tax levy, served 2,365 limited-English-proficient high school students at 14 sites in Manhattan, the Bronx, Brooklyn, and Queens. Designed for the substantial number of students who are over-age for their grade, the program offered the English-as-a-Second-Language (ESL) and bilingual…

THE DROPOUTS DID COME BACK, A SPECIAL SUMMER GUIDANCE SCHOOL PROGRAM.

ERIC Educational Resources Information Center

HICKMAN, RALPH D.

A SPECIAL SUMMER SCHOOL PROGRAM FOR 60 SELECTED HIGH SCHOOL DROPOUTS WAS CONDUCTED BY A COUNTY SCHOOLS OFFICE. A MAJOR PURPOSE WAS TO PREPARE THESE DROPOUTS, ATTITUDINALLY AND EDUCATIONALLY, TO REENTER A REGULAR SCHOOL PROGRAM. THE THREE COUNSELORS WERE ASSIGNED 20 STUDENTS EACH. THE STUDENTS WERE REQUIRED TO ATTEND DAILY CLASSES IN MATHEMATICS,…

Critical Components of a Summer Enrichment Program for Urban Low-Income Gifted Students

ERIC Educational Resources Information Center

Kaul, Corina R.; Johnsen, Susan K.; Witte, Mary M.; Saxon, Terrill F.

2015-01-01

Effective program models are needed for low-income youth. This article describes one successful summer enrichment program, University for Young People's Project Promise, and outlines three key components of a Partnership for Promoting Potential in Low-Income Gifted Students (Partnership Model), which is based on Lee, Olszewski-Kubilius, and…

Research and Teaching: Association of Summer Bridge Program Outcomes with STEM Retention of Targeted Demographic Groups

ERIC Educational Resources Information Center

Tomasko, David L.; Ridgway, Judith S.; Waller, Rocquel J.; Olesik, Susan V.

2016-01-01

Retention of students to science, technology, engineering, and mathematics (STEM) major has been studied for four cohorts participating in a summer bridge program supported by the National Science Foundation. Students participated in a 6-week program prior to their first term of enrollment at a research-intensive land grant university. Comparisons…

A Blended Summer School Experience for English Learners

ERIC Educational Resources Information Center

Koeppen, Olga Maritza

2016-01-01

This study analyzes Achieve3000, Lexia Core 5, and Imagine Learning software programs designed to increase student literacy levels in a six-week summer school program. The Brainology program was also used with 4th to 6th grade students to determine if there was an increase in growth mindset. Three elementary schools with the highest percentages of…

Summer Curriculum | Cancer Prevention Fellowship Program

Cancer.gov

All Cancer Prevention Fellows are required to attend the NCI Summer Curriculum in Cancer Prevention during their first full summer at NCI. The curriculum has two courses, which are also open to the general scientific community worldwide.

Risk of Interval Cancer in Fecal Immunochemical Test Screening Significantly Higher During the Summer Months: Results from the National Cancer Screening Program in Korea.

PubMed

Cha, Jae Myung; Suh, Mina; Kwak, Min Seob; Sung, Na Young; Choi, Kui Son; Park, Boyoung; Jun, Jae Kwan; Hwang, Sang-Hyun; Lee, Do-Hoon; Kim, Byung Chang; Lee, You Kyoung; Han, Dong Soo

2018-04-01

This study aimed to evaluate the impact of seasonal variations in climate on the performance of the fecal immunochemical test (FIT) in screening for colorectal cancer in the National Cancer Screening Program in Korea. Data were extracted from the National Cancer Screening Program databases for participants who underwent FIT between 2009 and 2010. We compared positivity rates, cancer detection rates, interval cancer rates, positive predictive value, sensitivity, and specificity for FIT during the spring, summer, fall, and winter seasons in Korea. In total, 4,788,104 FIT results were analyzed. FIT positivity rate was lowest during the summer months. In the summer, the positive predictive value of FIT was about 1.1 times (adjusted odds ratio (aOR) 1.08, 95% confidence interval (CI) 1.00-1.16) higher in the overall FIT group and about 1.3 times (aOR 1.29, 95% CI 1.10-1.50) higher in the quantitative FIT group, compared to those in the other seasons. Cancer detection rates, however, were similar regardless of season. Interval cancer risk was significantly higher in the summer for both the overall FIT group (aOR 1.16, 95% CI 1.07-1.27) and the quantitative FIT group (aOR 1.31, 95% CI 1.12-1.52). In addition, interval cancers in the rectum and distal colon were more frequently detected in the summer and autumn than in the winter. The positivity rate of FIT was lower in the summer, and the performance of the FIT screening program was influenced by seasonal variations in Korea. These results suggest that more efforts to reduce interval cancer during the summer are needed in population-based screening programs using FIT, particularly in countries with high ambient temperatures.

Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.

PubMed

Drilon, Alexander; Somwar, Romel; Mangatt, Biju P; Edgren, Henrik; Desmeules, Patrice; Ruusulehto, Anja; Smith, Roger S; Delasos, Lukas; Vojnic, Morana; Plodkowski, Andrew J; Sabari, Joshua; Ng, Kenneth; Montecalvo, Joseph; Chang, Jason; Tai, Huichun; Lockwood, William W; Martinez, Victor; Riely, Gregory J; Rudin, Charles M; Kris, Mark G; Arcila, Maria E; Matheny, Christopher; Benayed, Ryma; Rekhtman, Natasha; Ladanyi, Marc; Ganji, Gopinath

2018-06-01

NRG1 rearrangements are oncogenic drivers that are enriched in invasive mucinous adenocarcinomas (IMA) of the lung. The oncoprotein binds ERBB3-ERBB2 heterodimers and activates downstream signaling, supporting a therapeutic paradigm of ERBB3/ERBB2 inhibition. As proof of concept, a durable response was achieved with anti-ERBB3 mAb therapy (GSK2849330) in an exceptional responder with an NRG1 -rearranged IMA on a phase I trial (NCT01966445). In contrast, response was not achieved with anti-ERBB2 therapy (afatinib) in four patients with NRG1 -rearranged IMA (including the index patient post-GSK2849330). Although in vitro data supported the use of either ERBB3 or ERBB2 inhibition, these clinical results were consistent with more profound antitumor activity and downstream signaling inhibition with anti-ERBB3 versus anti-ERBB2 therapy in an NRG1 -rearranged patient-derived xenograft model. Analysis of 8,984 and 17,485 tumors in The Cancer Genome Atlas and MSK-IMPACT datasets, respectively, identified NRG1 rearrangements with novel fusion partners in multiple histologies, including breast, head and neck, renal, lung, ovarian, pancreatic, prostate, and uterine cancers. Significance: This series highlights the utility of ERBB3 inhibition as a novel treatment paradigm for NRG1 -rearranged cancers. In addition, it provides preliminary evidence that ERBB3 inhibition may be more optimal than ERBB2 inhibition. The identification of NRG1 rearrangements across various solid tumors supports a basket trial approach to drug development. Cancer Discov; 8(6); 686-95. ©2018 AACR. See related commentary by Wilson and Politi, p. 676 This article is highlighted in the In This Issue feature, p. 663 . ©2018 American Association for Cancer Research.

Chevron osteotomy with lateral release and adductor tenotomy for hallux valgus.

PubMed

Potenza, Vito; Caterini, Roberto; Farsetti, Pasquale; Forconi, Fabrizio; Savarese, Eugenio; Nicoletti, Simone; Ippolito, Ernesto

2009-06-01

Distal chevron osteotomy is a procedure widely performed for the surgical treatment of painful hallux valgus. The risks and benefits of a lateral capsular release and adductor tenotomy combined with chevron osteotomy are still debated. The aim of our study was to report the clinical and radiographic outcomes of this combined procedure in mild and moderate incongruent bunion deformities, with a hallux valgus angle (HVA) up to 40 degrees and an intermetatarsal angle (IMA) up to 20 degrees. Forty-two patients (52 feet) who consecutively underwent chevron osteotomy combined with lateral release and adductor tenotomy were reviewed 24-36 months after surgery. The mean age of the patients was 53.5 (range, 43 to 64) years. All the deformities were mild to moderate, with a mean preoperative value of 28 degrees in the HVA (range, 16 degrees to 40 degrees) and of 13 degrees in the IMA (range, 9 degrees to 20 degrees). At followup, the AOFAS hallux score improved from an average of 46 to an average of 88. The HVA and IMA had an average postoperative decrease respectively of 12 degrees and 6 degrees; lateral sesamoid displacement decreased by a mean of 15%. In no case did we observe infection or nonunion of the osteotomy. In one case, painless avascular necrosis of the first metatarsal head developed. Our short-term results show that distal chevron osteotomy combined with lateral release and adductor tenotomy is a feasible surgical option to address mild to moderate hallux valgus deformity, even with an IM angle between 15 and 20 degrees. Clinical and radiographic outcomes are generally good and patient satisfaction is generally high.

Role of intraoperative varus stress test for lateral soft tissue release during chevron bunion procedure.

PubMed

Kim, Hyong-Nyun; Suh, Dong-Hyun; Hwang, Pil-Sung; Yu, Sun-O; Park, Yong-Wook

2011-04-01

The purpose of this study was to evaluate the clinical results of distal chevron osteotomy performed in conjunction with selective lateral soft tissue release. The criterion for doing a lateral soft tissue release was assessed by determining the ease and completeness of passive hallux valgus correction at the time of surgery. Between August 2005 and November 2007, 48 feet in 43 patients classified as having mild to moderate hallux valgus were retrospectively studied. Distal chevron osteotomy without lateral soft tissue release was performed in 26 cases (Group 1) when passive correction of the hallux valgus deformity was possible. Distal chevron osteotomy with lateral soft tissue release was performed in 22 cases (Group 2) when passive correction was not possible. Average followup was 23 (range, 12 to 28) months. Clinical results were assessed using radiographic parameters [hallux valgus angle (HVA), first and second intermetatarsal angle (1,2 IMA)], AOFAS scale and patient's subjective satisfaction. For Group 1: the average correction of HVA was 12.8 degrees, the average correction of IMA was 4.7 degrees, and the AOFAS score improved an average of 29.2 points at the last followup. Thirteen patients were very satisfied and ten patients were satisfied with the results. No patient was dissatisfied. For Group 2: the average correction of HVA was 19.1 degrees, the average correction of IMA was 7 degrees and AOFAS score improved at an average of 31.8 points at the last followup. Twelve patients were very satisfied, seven patients were satisfied and one patient, who had stiffness of the first metatarsophalangeal joint, was dissatisfied with the result. Distal chevron osteotomy with selective lateral soft tissue release based on the ability to passively correct the hallux valgus deformity lead to safe and stable correction.

I-ImaS: intelligent imaging sensors

NASA Astrophysics Data System (ADS)

Griffiths, J.; Royle, G.; Esbrand, C.; Hall, G.; Turchetta, R.; Speller, R.

2010-08-01

Conventional x-radiography uniformly irradiates the relevant region of the patient. Across that region, however, there is likely to be significant variation in both the thickness and pathological composition of the tissues present, which means that the x-ray exposure conditions selected, and consequently the image quality achieved, are a compromise. The I-ImaS concept eliminates this compromise by intelligently scanning the patient to identify the important diagnostic features, which are then used to adaptively control the x-ray exposure conditions at each point in the patient. In this way optimal image quality is achieved throughout the region of interest whilst maintaining or reducing the dose. An I-ImaS system has been built under an EU Framework 6 project and has undergone pre-clinical testing. The system is based upon two rows of sensors controlled via an FPGA based DAQ board. Each row consists of a 160 mm × 1 mm linear array of ten scintillator coated 3T CMOS APS devices with 32 μm pixels and a readable array of 520 × 40 pixels. The first sensor row scans the patient using a fraction of the total radiation dose to produce a preview image, which is then interrogated to identify the optimal exposure conditions at each point in the image. A signal is then sent to control a beam filter mechanism to appropriately moderate x-ray beam intensity at the patient as the second row of sensors follows behind. Tests performed on breast tissue sections found that the contrast-to-noise ratio in over 70% of the images was increased by an average of 15% at an average dose reduction of 9%. The same technology is currently also being applied to baggage scanning for airport security.

Ischemia-modified albümin and malondialdehyde levels in patients with overt and subclinical hyperthyroidism: effects of treatment on oxidative stress.

PubMed

Erem, Cihangir; Suleyman, Akile Karacin; Civan, Nadim; Mentese, Ahmet; Nuhoglu, İrfan; Uzun, Aysegul; Ersoz, Halil Onder; Deger, Orhan

2015-01-01

The main purpose of this study was to evaluate the levels of ischemia-modified albumin (IMA) and malondialdehyde (MDA) in patients with OHyper and SHyper, to assess the effects of antithyroid drug (ATD) therapy on the oxidative stress (OS) parameters. Forty-five untreated patients with overt hyperthyroidism (OHyper), 20 untreated patients with subclinical hyperthyroidism (SHyper) and 30 age-and sex-matched healthy controls were prospectively included in the study. Biochemical and hormonal parameters were evaluated in all patients before and after treatment. Compared with the control subjects, the levels of MDA, glucose and TG were significantly increased in patients with SHyper (p<0.05), whereas LDL-C levels were significantly decreased (p<0.01). Patients with OHyper showed significantly elevated MDA and glucose levels (p<0.001) and significantly decreased LDL-C and HDL-C levels compared with the controls (p<0.01). In patients with Graves' disease, serum TSH levels were inversely correlated with plasma MDA levels (r: -0.42, p<0.05). Plasma MDA levels significantly decreased and levels of TC, LDL-C and HDL-C significantly increased in the groups of OHyper and SHyper after treatment. Serum IMA levels did not significantly change at baseline and with the therapy in all subjects. In conclusion, increased MDA levels in both patient groups represent increased lipid peroxidation which might play an important role in the pathogenesis of the atherosclerosis in these patients. Increased oxidative stress in patients with SHyper and OHyper could be improved by ATD therapy. Also, MDA can be used as a reliable marker of OS and oxidative damage, while IMA is considered to be inappropriate.

The Role of Integrated Modelling and Assessment for Decision-Making: Lessons from Water Allocation Issues in Australia

NASA Astrophysics Data System (ADS)

Jakeman, A. J.; Guillaume, J. H. A.; El Sawah, S.; Hamilton, S.

2014-12-01

Integrated modelling and assessment (IMA) is best regarded as a process that can support environmental decision-making when issues are strongly contested and uncertainties pervasive. To be most useful, the process must be multi-dimensional and phased. Principally, it must be tailored to the problem context to encompass diverse issues of concern, management settings and stakeholders. This in turn requires the integration of multiple processes and components of natural and human systems and their corresponding spatial and temporal scales. Modellers therefore need to be able to integrate multiple disciplines, methods, models, tools and data, and many sources and types of uncertainty. These dimensions are incorporated into iteration between the various phases of the IMA process, including scoping, problem framing and formulation, assessing options and communicating findings. Two case studies in Australia are employed to share the lessons of how integration can be achieved in these IMA phases using a mix of stakeholder participation processes and modelling tools. One case study aims to improve the relevance of modelling by incorporating stakeholder's views of irrigated viticulture and water management decision making. It used a novel methodology with the acronym ICTAM, consisting of Interviews to elicit mental models, Cognitive maps to represent and analyse individual and group mental models, Time-sequence diagrams to chronologically structure the decision making process, an All-encompassing conceptual model, and computational Models of stakeholder decision making. The second case uses a hydro-economic river network model to examine basin-wide impacts of water allocation cuts and adoption of farm innovations. The knowledge exchange approach used in each case was designed to integrate data and knowledge bearing in mind the contextual dimensions of the problem at hand, and the specific contributions that environmental modelling was thought to be able to make.

Conventional and novel body temperature measurement during rest and exercise induced hyperthermia.

PubMed

Towey, Colin; Easton, Chris; Simpson, Robert; Pedlar, Charles

2017-01-01

Despite technological advances in thermal sensory equipment, few core temperature (T CORE ) measurement techniques have met the established validity criteria in exercise science. Additionally, there is debate as to what method serves as the most practically viable, yet upholds the proposed measurement accuracy. This study assessed the accuracy of current and novel T CORE measurement techniques in comparison to rectal temperature (T REC ) as a reference standard. Fifteen well-trained subjects (11 male, 4 female) completed 60min of exercise at an intensity equating to the lactate threshold; measured via a discontinuous exercise test. T REC was significantly elevated from resting values (37.2±0.3°C) at the end of moderate intensity exercise (39.6±0.04°C; P=0.001). Intestinal telemetric pill (T PILL ) temperature and temporal artery temperature (T TEM ) did not differ significantly from T REC at rest or during exercise (P>0.05). However, aural canal temperature (T AUR ) and thermal imaging temperature (T IMA ) were both significantly lower than T REC (P<0.05). Bland Altman analysis revealed only T PILL was within acceptable limits of agreement (mean bias; 0.04°C), while T TEM , T AUR and T IMA demonstrated mean bias values outside of the acceptable range (>0.27°C). Against T REC , these results support the use of T PILL over all other techniques as a valid measure of T CORE at rest and during exercise induced hyperthermia. Novel findings illustrate that T IMA (when measured at the inner eye canthus) shows poor agreement to T REC during rest and exercise, which is similar to other 'surface' measures. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Tachycardia in breast reconstructive microsurgery: Affirmation of the IMA tachycardia syndrome.

PubMed

Sachanandani, N S; Kale, S S; Skolnick, G B; Barbour, J R; Myckatyn, T M

2015-06-01

The internal mammary vessels are frequently chosen as recipient vessels for breast free flap reconstruction. We have noticed that when using the internal mammary recipients that these patients have a propensity for tachycardia that was not previously observed. Our aim was to investigate the factors related to perioperative tachycardia in the microsurgical breast reconstruction population and to address whether use of the internal mammary system is a causative factor in tachycardia. A retrospective chart review was conducted to identify patients who underwent abdominal-based microvascular breast reconstruction at the Washington University School of Medicine between 2002 and 2012 to identify the presence of tachycardia. After application of exclusion criteria, 76 microvascular abdominal-based free flap reconstructions were identified. The internal mammary (IM) TRAM group (n = 24) and the thoracodorsal (TD) TRAM group (n = 52) were compared. A binomial logistic regression was performed with the presence of tachycardia as the dependent variable. There was a higher incidence of tachycardia in the IM TRAM group when compared to the TD TRAM group (p = 0.004). The variables predictive of tachycardia in our logistic regression model were IMA recipient (p = 0.04), need for transfusion (p = 0.03), and presence of fever (p = 0.01). Our study reaffirms that there are several factors that are predictive of tachycardia in the setting of microvascular breast reconstruction. The IMA syndrome should be a recognized cause of tachycardia as using these recipient vessels are shown to be predictive of postoperative tachycardia as shown in our study. Copyright © 2015 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

The use of Bjork's indications of growth for evaluation of extremes of skeletal morphology.

PubMed

Davidovitch, Moshe; Eleftheriadi, Iro; Kostaki, Anastasia; Shpack, Nir

2016-12-01

Morphological indicators within the cranium for prediction of mandibular growth patterns as reported by Bjork are: (1) inclination of the condylar head (ICH), (2) curvature of mandibular canal (CMC), (3) shape of the lower border of the mandible and specifically depth of the antegonial notch (AN), (4) inclination of the symphysis (ISY), (5) interincisal angle (IIA), (6) intermolar angle (IMA), and (7) lower anterior face height (LAFH). The purpose of this study was to examine the association of these indicators as they relate to extreme skeletal patterns observed in skeletally mature subjects. The pre-treatment lateral cephalometric radiographs of 395 post-growth subjects were randomly selected from the archives of a university orthodontic department. These were divided in three groups according to their MP-SN angle [normal: 28-36degrees (G1), hypodivergent: ≤26degrees (G2), hyperdivergent: ≥38degrees (G3)]. It was found that only LAFH was correlated to age across all groups. However, within G1, G2, and G3, and between genders, it was found that there were statistically significant differences for all indicators in relation to age, except IMA (P > 0.05). In addition, ISY and IMA had a predictive value lower than the chance level (0.5). Bjork's implant studies have contributed much to understanding facial-skeletal growth; however, this study suggests that their utilization as a tool in classifying extreme skeletal patterns requires careful evaluation of all the parameters involved. © The Author 2015. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Using No-Stakes Educational Testing to Mitigate Summer Learning Loss: A Pilot Study. Research Report. ETS RR-14-21

ERIC Educational Resources Information Center

Zaromb, Franklin; Adler, Rachel M.; Bruce, Kelly; Attali, Yigal; Rock, JoAnn

2014-01-01

This study investigates the benefits of no-stakes educational testing during students' summer vacation as a strategy to mitigate summer learning loss. Fifty-one students in Grades 3-8 from the Every Child Valued (ECV) and Lawrence Community Center (LCC) summer programs in Lawrenceville, NJ, took short, online assessments throughout the summer,…

EVALUATION AND FOLLOWUP STUDY OF A SUMMER SCIENCE AND MATHEMATICS PROGRAM FOR TALENTED SECONDARY SCHOOL STUDENTS.

ERIC Educational Resources Information Center

BASSETT, ROBERT D.; COOLEY, WILLIAM W.

THIS STUDY WAS TO EVALUATE A SUMMER PROGRAM IN SCIENCE AND MATHEMATICS FOR 60 PROMISING SCIENCE STUDENTS, AND TO DETERMINE THE EFFECTS OF SUCH A PROGRAM ON THE BEHAVIOR OF STUDENTS IN CLASSES DURING THE ENSUING YEAR AND ON THEIR FUTURE CAREER DECISIONS. THE FIRST 2 OF THE 10 WEEKS OF THIS PROGRAM THE STUDENTS WERE GIVEN ADVANCED INSTRUCTION BY…

Summer Internship Program for American Indian & Native Alaska College Students

ScienceCinema

None

2017-12-09

Argonne National Laboratory's Summer Internship Program for American Indian & Native Alaska College Students. Supported by the Office of Indian Energy and Economic Development (IEED) in partnership with the Council of Energy Resource Tribes (CERT) and the U.S. Department of Energy.

Summer Opportunities for Students.

ERIC Educational Resources Information Center

Winds of Change, 2003

2003-01-01

Eleven summer internships, work experience programs, research opportunities, and courses are described. Some offer stipends. Some are specifically for American Indian, minority, disadvantaged, or disabled students in high school or college. Most are in science or engineering related fields. Each entry contains a brief program description,…

Mississippi Magic: Summer Library Program, 1999.

ERIC Educational Resources Information Center

Hudspeth, Jean; Shurden, Lynn Fletcher

This manual for the 1999 Mississippi summer library program for preschool through elementary age children contains the following sections: (1) Introduction, including planning, promotional activities, sample radio spots and press releases, sample letters to parents, tips for including children with disabilities, a general bibliography, a…

The SUNY Summer Internship: The First Twenty Years.

ERIC Educational Resources Information Center

Mozlin, Rochelle; Suchoff, Irwin B.

1987-01-01

The State University of New York's innovative summer internship program bringing together 18 students between their third and fourth years to study functional vision care and vision therapy is described. Its history, program structure, recruitment and selection, and evaluation are highlighted. (MSE)

NURail Research Experience for Undergraduates (REU) Summer Program in Multimodal Freight Transportation Risk.

DOT National Transportation Integrated Search

2013-08-01

NURail hosted an REU Summer Program in Multimodal Freight Transportation Risk at the Rail Transportation and Engineering Center (RailTEC) in the Department of Civil and Environmental Engineering at the University of Illinois at Urbana-Champaign (UIUC...

Evaluation of a Summer Reading Program to Reduce Summer Setback

ERIC Educational Resources Information Center

Johnston, Jessica; Riley, Jessica; Ryan, Carey; Kelly-Vance, Lisa

2015-01-01

Summer setback, which is defined as a decline in academic achievement over the summer months, occurs in many academic areas but seems especially problematic in reading. We assessed students from a midwestern parochial school serving predominantly students from a low--socioeconomic status background for their reading achievement before they left…

Dusty D Ring

NASA Image and Video Library

2014-02-24

Saturn D ring is easy to overlook since it trapped between the brighter C ring and the planet itself. In this view from NASA Cassini spacecraft, all that can be seen of the D ring is the faint and narrow arc as it stretches from top right of the ima

A Formal Model of Partitioning for Integrated Modular Avionics

NASA Technical Reports Server (NTRS)

DiVito, Ben L.

1998-01-01

The aviation industry is gradually moving toward the use of integrated modular avionics (IMA) for civilian transport aircraft. An important concern for IMA is ensuring that applications are safely partitioned so they cannot interfere with one another. We have investigated the problem of ensuring safe partitioning and logical non-interference among separate applications running on a shared Avionics Computer Resource (ACR). This research was performed in the context of ongoing standardization efforts, in particular, the work of RTCA committee SC-182, and the recently completed ARINC 653 application executive (APEX) interface standard. We have developed a formal model of partitioning suitable for evaluating the design of an ACR. The model draws from the mathematical modeling techniques developed by the computer security community. This report presents a formulation of partitioning requirements expressed first using conventional mathematical notation, then formalized using the language of SRI'S Prototype Verification System (PVS). The approach is demonstrated on three candidate designs, each an abstraction of features found in real systems.

Long-Term Impact of the Enrichment Experiences in Engineering (E[superscript 3]) Summer Teacher Program

ERIC Educational Resources Information Center

Autenrieth, Robin L.; Lewis, Chance W.; Butler-Purry, Karen L.

2017-01-01

The Enrichment Experiences in Engineering (E[superscript 3] ) summer teacher program is hosted by the Dwight Look College of Engineering at Texas A&M University and is designed to provide engineering research experiences for Texas high school science and mathematics teachers. The mission of the E[superscript 3] program is to educate and excite…

Assessment of Factors Impacting Success for Incoming College Engineering Students in a Summer Bridge Program

ERIC Educational Resources Information Center

Reisel, John R.; Jablonski, Marissa; Hosseini, Hossein; Munson, Ethan

2012-01-01

A summer bridge program for incoming engineering and computer science freshmen has been used at the University of Wisconsin-Milwaukee from 2007 to 2010. The primary purpose of this program has been to improve the mathematics course placement for incoming students who initially place into a course below Calculus I on the math placement examination.…

The Learning Effects of an Ecology Enrichment Summer Program on Gifted Students from Mainstream and Diverse Cultural Backgrounds: A Preliminary Study

ERIC Educational Resources Information Center

Wang, Wen-Ling; Wu, Jiun-Wei; Lin, Yu-Chin

2006-01-01

Enrichment is one of the important educational models for gifted students. However, the research on gifted enrichment programs rarely leads to instructional interventions for culturally diverse students. The purposes of this study were: (a) to propose an ecology enrichment summer program for gifted students from mainstream and diverse cultural…

Middle/High School Students in the Research Laboratory: A Summer Internship Program Emphasizing the Interdisciplinary Nature of Biology

ERIC Educational Resources Information Center

McMiller, Tracee; Lee, Tameshia; Saroop, Ria; Green, Tyra; Johnson, Casonya M.

2006-01-01

We describe an eight-week summer Young Scientist in Training (YSIT) internship program involving middle and high school students. This program exposed students to current basic research in molecular genetics, while introducing or reinforcing principles of the scientific method and demonstrating the uses of mathematics and chemistry in biology. For…

USAF/SCEEE Summer Faculty Research Program (1979). Volume 2

DTIC Science & Technology

1979-12-01

Summer Faculty Research Program participants. The program designed to stimulate ’Ilk scientific and engineering interaction between university faculty...Prog., Dept. of Industrial Engineering Facility design and location theory University of Oklahoma and routing and distribution systems 202 W. Boyd...Theory & Assistant Professor of Management Adninistration, 1975 University of Akron S.ec aIty: Organization Design Akron, OH 44325 Assigned: AFBRMC

Poor Administration of the 1977 Summer Program for Economically Disadvantaged Youth in New York City.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Div. of Human Resources.

This report provides background and data from an investigation of New York City's summer youth employment program. It concludes that the program was poorly planned and poorly administered by both the Department of Labor and the city. Although some of the worksites visited were providing useful work experience to enrolled youths, over half of the…

The Role of the Campus Visit and Summer Orientation Program in the Modification of Student Expectations about College.

ERIC Educational Resources Information Center

Singer, Wren

2003-01-01

Studied the messages being conveyed to prospective students in campus visits and summer orientation sessions at the University of Wisconsin-Madison. Findings for 497 prospective students show that the visit and orientation program may be effective, but programs are trying to communicate too much. Findings also show the importance of the campus…

Unique programming: an examination of the benefits of a free choice program

Treesearch

Dorothy L. Schmalz; Deborah L. Kerstetter; Harry C. Zinn

2002-01-01

This study was an investigation of a free choice program and the benefits free choice yields on the developing characteristics of self-esteem and intrinsic motivation among adolescent girls. Both quantitative and qualitative data were collected at Brown Ledge Camp, an all girls summer camp outside of Burlington, Vermont, during the summer of 2000. Quantitative results...

Challenges in Serving Rural American Children through the Summer Food Service Program. Issue Brief No. 13

ERIC Educational Resources Information Center

Wauchope, Barbara; Stracuzzi, Nena

2010-01-01

Many families rely on U.S. Department of Agriculture (USDA)-funded school lunch and breakfast programs to make the family's food budget stretch, improving their food security throughout the school year. These programs feed about 31 million students annually. During the summer where schools are not in session, food security decreases. The USDA…

A Pilot Study of a Kindergarten Summer School Reading Program in High-Poverty Urban Schools

ERIC Educational Resources Information Center

Denton, Carolyn A.; Solari, Emily J.; Ciancio, Dennis J.; Hecht, Steven A.; Swank, Paul R.

2010-01-01

This pilot study examined an implementation of a kindergarten summer school reading program in 4 high-poverty urban schools. The program targeted both basic reading skills and oral language development. Students were randomly assigned to a treatment group (n = 25) or a typical practice comparison group (n = 28) within each school; however,…