Finland Becomes Eleventh ESO Member State

NASA Astrophysics Data System (ADS)

2004-07-01

Finland has become the eleventh member state of the European Southern Observatory (ESO) [1]. The formal accession procedure was carried through as planned and has now been completed. Following the signing of the corresponding Agreement earlier this year (ESO PR 02/04), acceptance by the Finnish Parliament and ratification by the Finnish President of the Agreement as well as the ESO Convention and the associated protocols in June [2] and the deposit of the instruments of accession today, Finland has now officially joined ESO. ESO warmly welcomes the new member country and its scientific community that is renowned for their expertise in many frontline areas. The related opportunities will contribute to strenghtening of pioneering research with the powerful facilities at ESO's observatories, to the benefit of Astronomy and Astrophysics as well as European science in general. ESO also looks forward to collaboration with the Finnish high-tech industry. For Finland, the membership in ESO is motivated by scientific and technological objectives as well as by the objective of improving the public understanding of science. The Finnish Government is committed to increasing the public research funding in order to improve the quality, impact and internationalisation of research. Membership in ESO offers unique facilities for astronomical research which would not otherwise be available for Finnish astronomers. Finland is also very interested in taking part in technological development projects in fields like ICT, optics and instrumentation. For young scientists and engineers, ESO is a challenging, international working and learning environment. Finland has already taken part in the educational programmes of ESO, and as a member this activity will be broadened and intensified. In Finland there are also several science journalists and a large community of amateur astronomers who will be very happy to take part in ESO's outreach activities.

Three Good Reasons for Celebrating at the ESO/ST-ECF Science Archive Facility

NASA Astrophysics Data System (ADS)

2000-12-01

10/99. Celebrating the 10th anniversary Due to a happy coincidence, the Archive passes two other milestones almost exactly at the time of its ten-year anniversary: the 10,000th request for data has just arrived, and active user number 2000 has just signed up to start using the Archive . Dataset number 10000 was requested by Danish astronomer Søren Larsen who works at the University of California (USA). He asked for images of galaxies taken with the Hubble Space Telescope and expressed great satisfaction with the material: "The extremely sharp images from Hubble have provided a quantum leap forward in our ability to study star clusters in external galaxies. We now know that some galaxies contain extremely bright young star clusters. These might constitute a "link" between open and globular clusters as we know them in the Milky Way galaxy in which we live. We are now trying to understand whether all these clusters really form in the same basic way." Active user number 2000 is Swiss astronomer Frédéric Pont , working at the Universidad de Chile: "We use observations from the ESO VLT Unit Telescopes to map the chemical and star-formation history of dwarf galaxies in the Local Group. The stars we are looking at are very faint and we simply need the large size and excellent quality of VLT to observe them in detail. With the new data, we can really move forward in this fundamental research field." ESO PR Photo 34/00 ESO PR Photo 34/00 [Preview - JPEG: 400 x 281 pix - 63k] [Normal - JPEG: 800 x 562 pix - 224k] [Full-Res - JPEG: 1024 x 714 pix - 336k] Caption : PR Photo 34/00 shows the frontpage of the new brochure that describes the ESO/ST-ECF Science Archive Facility (available in PDF version on the web). The collage shows the Hubble Space Telescope above the world's largest optical/infrared telescope, the Very Large Telescope (VLT). To celebrate this special occasion, a 4-page brochure has been prepared that describes the Archive and its various services. The brochure

Deep Sky Diving with the ESO New Technology Telescope

NASA Astrophysics Data System (ADS)

1998-01-01

Preparations for future cosmological observations with the VLT Within a few months, the first 8.2-meter Unit Telescope of the ESO Very Large Telescope (VLT) array will open its eye towards the sky above the Atacama desert. As documented by recent Press Photos from ESO, the construction work at the Paranal VLT Observatory is proceeding rapidly. Virtually all of the telescope components, including the giant Zerodur mirror (cf. ESO PR Photos 35a-l/97 ), are now on the mountain. While the integration of the telescope and its many optical, mechanical and electronic components continues, astronomers in the ESO member countries and at ESO are now busy defining the observing programmes that will be carried out with the new telescope, soon after it enters into operation. In this context, new and exciting observations have recently been obtained with the 3.5-m New Technology Telescope at the ESO La Silla Observatory, 600 km to the south of Paranal. How to record the faintest and most remote astronomical objects With its very large mirror surface (and correspondingly great light collecting power), as well as an unsurpassed optical quality, the VLT will be able to look exceedingly far out into the Universe, well beyond current horizons. The best technique to record the faintest possible light and thus the most remote celestial objects, is to combine large numbers of exposures of the same field with slightly different telescope pointing. This increases the total number of photons recorded and by imaging the stars and galaxies on different areas (pixels) of the detector, the signal-to-noise ratio and hence the visibility of the faintest objects is improved. The famous Hubble Deep Field Images were obtained in this way by combining over 300 single exposures and they show myriads of faint galaxies in the distant realms of the Universe. The NTT as test bench for the VLT ESO is in the fortunate situation of possessing a `prototype' model of the Very Large Telescope, the 3.5-m New

Dutch Minister of Science Visits ESO Facilities in Chile

NASA Astrophysics Data System (ADS)

2005-05-01

," expressed Mrs. Maria van der Hoeven during her visit. "An almost unique level of international cooperation is achieved at ESO, and everything is done by those who can do it best, irrespective of their country or institution. This spirit of excellence is an example for all Europe, notably for the new European Research Council." Catherine Cesarsky, ESO Director General, remarked that Dutch astronomers have been part of ESO from the beginning: "The Dutch astronomy community and industry play a major role in various aspects of the Very Large Telescope, and more particularly in its interferometric mode. With their long-based expertise in radio astronomy, Dutch astronomers greatly contribute in this field, and are now also playing a major role in the construction of ALMA. It is thus a particularly great pleasure to receive Her Excellency, Mrs. Maria van der Hoeven." ESO PR Photo 16d/05 ESO PR Photo 16d/05 Dutch Minister Maria van der Hoeven at Chajnantor - I [Preview - JPEG: 400 x 480 pix - 207k] [Normal - JPEG: 800 x 959 pix - 617k] ESO PR Photo 16e/05 ESO PR Photo 16e/05 Dutch Minister Maria van der Hoeven at Chajnantor - II [Preview - JPEG: 400 x 605 pix - 179k] [Normal - JPEG: 800 x 1210 pix - 522k] Caption: ESO PR Photo 16d/05: In front of the APEX antenna at Chajnantor. From left to right: Prof. Piet van der Kruit, Mrs. Maria van der Hoeven, Prof. Tim de Zeeuw, and Prof. Ewine van Dishoeck. ESO PR Photo 16e/05 shows the Delegation on the 5000m high Llano de Chajnantor plateau. From left to right: Dr. Leo Le Duc, Prof. Felix Mirabel, Prof. Tim de Zeeuw, Prof. Ewine van Dishoeck, Dr. Cornelius van Bochove, Mrs. Maria van der Hoeven, Mr. Hans van der Vlies, Dr. Joerg Eschwey, Mr. Hinkinus Nijenhuis, Prof. Piet van der Kruit, Mr. Hans van den Broek, and Mr. Eduardo Donoso. The delegation spent the night at the Observatory before heading further North in the Chilean Andes to San Pedro de Atacama and from there to the Operation Support Facility of the future ALMA Observatory. On

ESO imaging survey: infrared observations of CDF-S and HDF-S

NASA Astrophysics Data System (ADS)

Olsen, L. F.; Miralles, J.-M.; da Costa, L.; Benoist, C.; Vandame, B.; Rengelink, R.; Rité, C.; Scodeggio, M.; Slijkhuis, R.; Wicenec, A.; Zaggia, S.

2006-06-01

This paper presents infrared data obtained from observations carried out at the ESO 3.5 m New Technology Telescope (NTT) of the Hubble Deep Field South (HDF-S) and the Chandra Deep Field South (CDF-S). These data were taken as part of the ESO Imaging Survey (EIS) program, a public survey conducted by ESO to promote follow-up observations with the VLT. In the HDF-S field the infrared observations cover an area of ~53 square arcmin, encompassing the HST WFPC2 and STIS fields, in the JHKs passbands. The seeing measured in the final stacked images ranges from 0.79 arcsec to 1.22 arcsec and the median limiting magnitudes (AB system, 2'' aperture, 5σ detection limit) are J_AB˜23.0, H_AB˜22.8 and K_AB˜23.0 mag. Less complete data are also available in JKs for the adjacent HST NICMOS field. For CDF-S, the infrared observations cover a total area of ~100 square arcmin, reaching median limiting magnitudes (as defined above) of J_AB˜23.6 and K_AB˜22.7 mag. For one CDF-S field H band data are also available. This paper describes the observations and presents the results of new reductions carried out entirely through the un-supervised, high-throughput EIS Data Reduction System and its associated EIS/MVM C++-based image processing library developed, over the past 5 years, by the EIS project and now publicly available. The paper also presents source catalogs extracted from the final co-added images which are used to evaluate the scientific quality of the survey products, and hence the performance of the software. This is done comparing the results obtained in the present work with those obtained by other authors from independent data and/or reductions carried out with different software packages and techniques. The final science-grade catalogs together with the astrometrically and photometrically calibrated co-added images are available at CDS.

Production of Previews and Advanced Data Products for the ESO Science Archive

NASA Astrophysics Data System (ADS)

Rité, C.; Slijkhuis, R.; Rosati, P.; Delmotte, N.; Rino, B.; Chéreau, F.; Malapert, J.-C.

2008-08-01

We present a project being carried out by the Virtual Observatory Systems Department/Advanced Data Products group in order to populate the ESO Science Archive Facility with image previews and advanced data products. The main goal is to provide users of the ESO Science Archive Facility with the possibility of viewing pre-processed images associated with instruments like WFI, ISAAC and SOFI before actually retrieving the data for full processing. The image processing is done by using the ESO/MVM image reduction software developed at ESO, to produce astrometrically calibrated FITS images, ranging from simple previews of single archive images, to fully stacked mosaics. These data products can be accessed via the ESO Science Archive Query Form and also be viewed with the browser VirGO {http://archive.eso.org/cms/virgo}.

ESO's Hidden Treasures Brought to Light

NASA Astrophysics Data System (ADS)

2011-01-01

ESO's Hidden Treasures 2010 astrophotography competition attracted nearly 100 entries, and ESO is delighted to announce the winners. Hidden Treasures gave amateur astronomers the opportunity to search ESO's vast archives of astronomical data for a well-hidden cosmic gem. Astronomy enthusiast Igor Chekalin from Russia won the first prize in this difficult but rewarding challenge - the trip of a lifetime to ESO's Very Large Telescope at Paranal, Chile. The pictures of the Universe that can be seen in ESO's releases are impressive. However, many hours of skilful work are required to assemble the raw greyscale data captured by the telescopes into these colourful images, correcting them for distortions and unwanted signatures of the instrument, and enhancing them so as to bring out the details contained in the astronomical data. ESO has a team of professional image processors, but for the ESO's Hidden Treasures 2010 competition, the experts decided to give astronomy and photography enthusiasts the opportunity to show the world what they could do with the mammoth amount of data contained in ESO's archives. The enthusiasts who responded to the call submitted nearly 100 entries in total - far exceeding initial expectations, given the difficult nature of the challenge. "We were completely taken aback both by the quantity and the quality of the images that were submitted. This was not a challenge for the faint-hearted, requiring both an advanced knowledge of data processing and an artistic eye. We are thrilled to have discovered so many talented people," said Lars Lindberg Christensen, Head of ESO's education and Public Outreach Department. Digging through many terabytes of professional astronomical data, the entrants had to identify a series of greyscale images of a celestial object that would reveal the hidden beauty of our Universe. The chance of a great reward for the lucky winner was enough to spur on the competitors; the first prize being a trip to ESO's Very Large

ESO's VLT Helps ESA's Rosetta Spacecraft Prepare to Ride on a Cosmic Bullet

NASA Astrophysics Data System (ADS)

2002-02-01

New Images of Comet Wirtanen's Nucleus [1] Summary New images of Comet Wirtanen's 1-km 'dirty snowball' nucleus have been obtained with the ESO Very Large Telescope at Paranal (Chile). They show this object at a distance of approx. 435 million km from the Sun, about the same as when the Rosetta spacecraft of the European Space Agency (ESA) arrives in 2011. The new observations indicate that the comet has a very low degree of activity at this point in its orbit - almost no material is seen around the nucleus. This means that there will not be so much dust near the nucleus as to make the planned landing dramatically difficult. PR Photo 06a/02 : The Nucleus of Comet Wirtanen (composite photo). PR Photo 06b/02 : Comet Wirtanen's motion in the sky (animated). A distant target ESO PR Photo 06a/02 ESO PR Photo 06a/02 [Preview - JPEG: 400 x 445 pix - 120k] [Normal - JPEG: 800 x 890 pix - 1.1M] ESO PR Photo 06b/02 ESO PR Photo 06b/02 [Animated GIF: 400 x 420 pix - 312k] Caption : PR Photo 06a/02 shows a (false-colour) composite image of the nucleus of Comet Wirtanen (the point of light at the centre), recorded on December 9, 2001, with the FORS2 multi-mode instrument at the 8.2-m VLT YEPUN Unit Telescope. It is based on four exposures and since the telescope was set to track the motion of the comet in the sky, the images of stars in the field are seen as four consecutive trails. The measured brightness and the fact that the image of the comet's 'dirty snowball' nucleus is almost star-like indicates that it is surrounded by a very small amount of gas or dust. The diameter of the nucleus is about 1 km and the distance to the comet from the Earth was approx. 534 million km. In PR Photo 06b/02 , the four exposures have been combined to show the motion of the comet during the four exposures. Technical information about the photos is available below. Chase a fast-moving comet, land on it and 'ride' it while it speeds up towards the Sun: not the script of a science-fiction movie

Relations Between Chile and ESO

NASA Astrophysics Data System (ADS)

1994-06-01

As announced in an earlier Press Release (PR 08/94 of 6 May 1994), a high-ranking ESO delegation visited Santiago de Chile during the week of 24 - 28 May 1994 to discuss various important matters of mutual interest with the Chilean Government. It consisted of Dr. Peter Creola (President of ESO Council), Dr. Catherine Cesarsky (Vice-President of ESO Council), Dr. Henrik Grage (Former Vice-President of ESO Council) and Professor Riccardo Giacconi (ESO Director General), the latter accompanied by his advisers. THE SUPPLEMENTARY TREATY BETWEEN CHILE AND ESO Following a meeting with the ambassadors to Chile of the eight ESO member countries, the ESO delegation was received by the Chilean Minister of Foreign Affairs, Mr. Carlos Figueroa, and members of his staff. The ESO delegation was pleased to receive assurances that the present Chilean Government, like its predecessors, will continue to honour all contractual agreements, in particular the privileges and immunities of this Organisation, which were laid down in the Treaty between ESO and Chile that was signed by the parties in 1963 and ratified the following year. The discussions covered some aspects of the proposed Supplementary Treaty which has been under preparation during the past year. This included in particular the desire of the Chilean side to further increase the percentage of guaranteed time for Chilean astronomers at the future ESO Very Large Telescope (VLT) and also the rules governing the installation by ESO member countries of additional telescopes at the ESO observatories in Chile. ESO invited a Chilean delegation to visit the ESO Headquarters in Garching (Germany) later this year for the final adjustment of the text of the Supplementary Treaty, after which it should be possible to proceed rapidly with the signing and ratification by the Chilean Parliament and the ESO Council. THE SITUATION AROUND PARANAL The ESO delegation expressed its deep concern to the Chilean Government about the continuing legal

Sharpest Ever VLT Images at NAOS-CONICA "First Light"

NASA Astrophysics Data System (ADS)

2001-12-01

demonstration of the value of international collaboration. ESO and its partner institutes and companies in France and Germany have worked a long time towards this goal - with the first, extremely promising results, we shall soon be able to offer a new and fully tuned instrument to our wide research community." The NAOS adaptive optics corrector was built, under an ESO contract, by Office National d'Etudes et de Recherches Aérospatiales (ONERA) , Laboratoire d'Astrophysique de Grenoble (LAOG) and the DESPA and DASGAL laboratories of the Observatoire de Paris in France, in collaboration with ESO. The CONICA infra-red camera was built, under an ESO contract, by the Max-Planck-Institut für Astronomie (MPIA) (Heidelberg) and the Max-Planck Institut für Extraterrestrische Physik (MPE) (Garching) in Germany, in collaboration with ESO. The present event happens less than four weeks after "First Fringes" were achieved for the VLT Interferometer (VLTI) with two of the 8.2-m Unit Telescopes. No wonder that a spirit of great enthusiasm reigns at Paranal! Information for the media: ESO is producing a Video News Release ( ESO Video News Reel No. 13 ) with sequences from the NAOS-CONICA "First Light" event at Paranal, a computer animation illustrating the principle of adaptive optics in NAOS-CONICA, as well as the first astronomical images obtained. In addition to the usual distribution, this VNR will also be transmitted via satellite Friday 7 December 2001 from 09:00 to 09:15 CET (10:00 to 10:15 UT) on "Europe by Satellite" . These video images may be used free of charge by broadcasters. Satellite details, the script and the shotlist will be on-line from 6 December on the ESA TV Service Website http://television.esa.int. Also a pre-view Real Video Stream of the video news release will be available as of that date from this URL. Video Clip 07/01 : Various video scenes related to the NAOS-CONICA "First Light" Event ( ESO Video News Reel No. 13 ). PR Photo 33a/01 : NAOS-CONICA "First light

ESO and Chile: 10 Years of Productive Scientific Collaboration

NASA Astrophysics Data System (ADS)

2006-06-01

ESO and the Government of Chile launched today the book "10 Years Exploring the Universe", written by the beneficiaries of the ESO-Chile Joint Committee. This annual fund provides grants for individual Chilean scientists, research infrastructures, scientific congresses, workshops for science teachers and astronomy outreach programmes for the public. In a ceremony held in Santiago on 19 June 2006, the European Organisation for Astronomical Research in the Southern Hemisphere (ESO) and the Chilean Ministry of Foreign Affairs marked the 10th Anniversary of the Supplementary Agreement, which granted to Chilean astronomers up to 10 percent of the total observing time on ESO telescopes. This agreement also established an annual fund for the development of astronomy, managed by the so-called "ESO-Chile Joint Committee". ESO PR Photo 21/06 ESO PR Photo 21/06 Ten Years ESO-Chile Agreement Ceremony The celebration event was hosted by ESO Director General, Dr. Catherine Cesarsky, and the Director of Special Policy for the Chilean Ministry of Foreign Affairs, Ambassador Luis Winter. "ESO's commitment is, and always will be, to promote astronomy and scientific knowledge in the country hosting our observatories", said ESO Director General, Dr. Catherine Cesarsky. "We hope Chile and Europe will continue with great achievements in this fascinating joint adventure, the exploration of the universe." On behalf of the Government of Chile, Ambassador Luis Winter outlined the historical importance of the Supplementary Agreement, ratified by the Chilean Congress in 1996. "Such is the magnitude of ESO-Chile Joint Committee that, only in 2005, this annual fund represented 8 percent of all financing sources for Chilean astronomy, including those from Government and universities", Ambassador Winter said. The ESO Representative and Head of Science in Chile, Dr. Felix Mirabel, and the appointed Chilean astronomer for the ESO-Chile Joint Committee, Dr. Leonardo Bronfman, also took part in the

Czech Republic to Become Member of ESO

NASA Astrophysics Data System (ADS)

2006-12-01

Today, an agreement was signed in Prague between ESO and the Czech Republic, aiming to make the latter become a full member of ESO as of 1 January 2007. "The future membership of the Czech Republic in ESO opens for the Czech astronomers completely new opportunities and possibilities. It will foster this discipline on the highest quality level and open new opportunities for Czech industry to actively cooperate in research and development of high-tech instruments for astronomical research," said Miroslava Kopicová, Minister of Education, Youth and Sports of the Czech Republic. ESO PR Photo 52/06 ESO PR Photo 52/06 Signing Ceremony "We warmly welcome the Czech Republic as the thirteenth member of ESO," said Catherine Cesarsky, ESO's Director General. "The timing couldn't be better chosen: with the Very Large Telescope, Europe is now at the forefront of ground-based astronomy, and with the construction of ALMA and the final studies for the European Extremely Large Telescope, we will ensure that this will remain so for several decades. We look forward to working together with our Czech colleagues towards these successes." The signing event took place at the Czech Ministry of Education, Youth and Sports in Prague. Following ratification by the Czech Parliament, the Czech Republic with thus join the twelve present member states of ESO, the European Organisation for Astronomical Research in the Southern Hemisphere: Belgium, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. The Czech Republic is the first country from Central and Eastern Europe to join ESO. Astronomy in the Czech Republic has a very long tradition that dates from as far back as 3500 BC. Four centuries ago, Tycho Brahe and Johannes Kepler established themselves in Prague at the invitation of the emperor Rudolph II, laying the ground for the first golden age in astronomy. Later, eminent scientists such as Christian Doppler, Ernst Mach and

ESO

Science.gov Websites

2009 100 Hours of Astronomy The Eye 3D IMAX® 3D Film Hidden Universe Open House Day 2011 Open House and Jupiter - 1994 Comet Hale Bopp - 1994 Astronomy Communication Seminars Outreach Education Educational Material Science in School ESO Astronomy Camp 2017 ESO Astronomy Camp 2016 ESO Astronomy Camp 2015

The ESO Educational Office Reaches Out towards Europe's Teachers

NASA Astrophysics Data System (ADS)

2001-12-01

ESA/ESO Astronomy Exercises Provide a Taste of Real Astronomy [1] Summary The European Southern Observatory (ESO) has been involved in many Europe-wide educational projects during the past years, in particular within European Science Weeks sponsored by the European Commission (EC). In order to further enhance the significant educational potential inherent in the numerous scientific endeavours now carried out by Europe's astronomers with ESO front-line telescope facilities, it has been decided to set up an Educational Office within the ESO EPR Department. It will from now on work closely with astronomy-oriented teachers, in particular at the high-school level , providing support, inspiration and new materials. Much of this interaction will happen via the European Association for Astronomy Education (EAAE) In this context, and in collaboration with the European Space Agency (ESA) , the first instalments of the "ESA/ESO Astronomy Exercise Series" have just been published, on the web ( http://www.astroex.org ) and in print (6 booklets totalling 100 pages; provided free-of-charge to teachers on request). They allow 16-19 year old students to gain exciting hands-on experience in astronomy, making realistic calculations with data obtained from observations by some of the world's best telescopes, the NASA/ESA Hubble Space Telescope (HST) and ESO's Very Large Telescope (VLT) . PR Photo 36/01 : The "ESA/ESO Astronomy Exercise Series" . Educational projects at ESO The European Southern Observatory (ESO) , through its Education and Public Relations Department (EPR) , has long been involved in educational activities, in particular by means of Europe-wide projects during successive European Science Weeks , with support from the European Commission (EC) . A most visible outcome has been the creation of the trailblazing European Association for Astronomy Education (EAAE) - this was first discussed at an international meeting at the ESO Headquarters in November 1994 with the

ESO imaging survey: optical deep public survey

NASA Astrophysics Data System (ADS)

Mignano, A.; Miralles, J.-M.; da Costa, L.; Olsen, L. F.; Prandoni, I.; Arnouts, S.; Benoist, C.; Madejsky, R.; Slijkhuis, R.; Zaggia, S.

2007-02-01

This paper presents new five passbands (UBVRI) optical wide-field imaging data accumulated as part of the DEEP Public Survey (DPS) carried out as a public survey by the ESO Imaging Survey (EIS) project. Out of the 3 square degrees originally proposed, the survey covers 2.75 square degrees, in at least one band (normally R), and 1.00 square degrees in five passbands. The median seeing, as measured in the final stacked images, is 0.97 arcsec, ranging from 0.75 arcsec to 2.0 arcsec. The median limiting magnitudes (AB system, 2´´ aperture, 5σ detection limit) are UAB=25.65, BAB=25.54, VAB=25.18, RAB = 24.8 and IAB =24.12 mag, consistent with those proposed in the original survey design. The paper describes the observations and data reduction using the EIS Data Reduction System and its associated EIS/MVM library. The quality of the individual images were inspected, bad images discarded and the remaining used to produce final image stacks in each passband, from which sources have been extracted. Finally, the scientific quality of these final images and associated catalogs was assessed qualitatively by visual inspection and quantitatively by comparison of statistical measures derived from these data with those of other authors as well as model predictions, and from direct comparison with the results obtained from the reduction of the same dataset using an independent (hands-on) software system. Finally to illustrate one application of this survey, the results of a preliminary effort to identify sub-mJy radio sources are reported. To the limiting magnitude reached in the R and I passbands the success rate ranges from 66 to 81% (depending on the fields). These data are publicly available at CDS. Based on observations carried out at the European Southern Observatory, La Silla, Chile under program Nos. 164.O-0561, 169.A-0725, and 267.A-5729. Appendices A, B and C are only available in electronic form at http://www.aanda.org

ALMA On the Move - ESO Awards Important Contract for the ALMA Project

NASA Astrophysics Data System (ADS)

2005-12-01

Only two weeks after awarding its largest-ever contract for the procurement of antennas for the Atacama Large Millimeter Array project (ALMA), ESO has signed a contract with Scheuerle Fahrzeugfabrik GmbH, a world-leader in the design and production of custom-built heavy-duty transporters, for the provision of two antenna transporting vehicles. These vehicles are of crucial importance for ALMA. ESO PR Photo 41a/05 ESO PR Photo 41a/05 The ALMA Transporter (Artist's Impression) [Preview - JPEG: 400 x 756 pix - 234k] [Normal - JPEG: 800 x 1512 pix - 700k] [Full Res - JPEG: 1768 x 3265 pix - 2.3M] Caption: Each of the ALMA transporters will be 10 m wide, 4.5 m high and 16 m long. "The timely awarding of this contract is most important to ensure that science operations can commence as planned," said ESO Director General Catherine Cesarsky. "This contract thus marks a further step towards the realization of the ALMA project." "These vehicles will operate in a most unusual environment and must live up to very strict demands regarding performance, reliability and safety. Meeting these requirements is a challenge for us, and we are proud to have been selected by ESO for this task," commented Hans-Jörg Habernegg, President of Scheuerle GmbH. ESO PR Photo 41b/05 ESO PR Photo 41b/05 Signing the Contract [Preview - JPEG: 400 x 572 pix - 234k] [Normal - JPEG: 800 x 1143 pix - 700k] [HiRes - JPEG: 4368 x 3056 pix - 2.3M] Caption: (left to right) Mr Thomas Riek, Vice-President of Scheuerle GmbH, Dr Catherine Cesarsky, ESO Director General and Mr Hans-Jörg Habernegg, President of Scheuerle GmbH. When completed on the high-altitude Chajnantor site in Chile, ALMA is expected to comprise more than 60 antennas, which can be placed in different locations on the plateau but which work together as one giant telescope. Changing the relative positions of the antennas and thus also the configuration of the array allows for different observing modes, comparable to using a zoom lens, offering

Deepest Wide-Field Colour Image in the Southern Sky

NASA Astrophysics Data System (ADS)

2003-01-01

LA SILLA CAMERA OBSERVES CHANDRA DEEP FIELD SOUTH ESO PR Photo 02a/03 ESO PR Photo 02a/03 [Preview - JPEG: 400 x 437 pix - 95k] [Normal - JPEG: 800 x 873 pix - 904k] [HiRes - JPEG: 4000 x 4366 pix - 23.1M] Caption : PR Photo 02a/03 shows a three-colour composite image of the Chandra Deep Field South (CDF-S) , obtained with the Wide Field Imager (WFI) camera on the 2.2-m MPG/ESO telescope at the ESO La Silla Observatory (Chile). It was produced by the combination of about 450 images with a total exposure time of nearly 50 hours. The field measures 36 x 34 arcmin 2 ; North is up and East is left. Technical information is available below. The combined efforts of three European teams of astronomers, targeting the same sky field in the southern constellation Fornax (The Oven) have enabled them to construct a very deep, true-colour image - opening an exceptionally clear view towards the distant universe . The image ( PR Photo 02a/03 ) covers an area somewhat larger than the full moon. It displays more than 100,000 galaxies, several thousand stars and hundreds of quasars. It is based on images with a total exposure time of nearly 50 hours, collected under good observing conditions with the Wide Field Imager (WFI) on the MPG/ESO 2.2m telescope at the ESO La Silla Observatory (Chile) - many of them extracted from the ESO Science Data Archive . The position of this southern sky field was chosen by Riccardo Giacconi (Nobel Laureate in Physics 2002) at a time when he was Director General of ESO, together with Piero Rosati (ESO). It was selected as a sky region towards which the NASA Chandra X-ray satellite observatory , launched in July 1999, would be pointed while carrying out a very long exposure (lasting a total of 1 million seconds, or 278 hours) in order to detect the faintest possible X-ray sources. The field is now known as the Chandra Deep Field South (CDF-S) . The new WFI photo of CDF-S does not reach quite as deep as the available images of the "Hubble Deep Fields

Using ESO Reflex with Web Services

NASA Astrophysics Data System (ADS)

Järveläinen, P.; Savolainen, V.; Oittinen, T.; Maisala, S.; Ullgrén, M. Hook, R.

2008-08-01

ESO Reflex is a prototype graphical workflow system, based on Taverna, and primarily intended to be a flexible way of running ESO data reduction recipes along with other legacy applications and user-written tools. ESO Reflex can also readily use the Taverna Web Services features that are based on the Apache Axis SOAP implementation. Taverna is a general purpose Web Service client, and requires no programming to use such services. However, Taverna also has some restrictions: for example, no numerical types such integers. In addition the preferred binding style is document/literal wrapped, but most astronomical services publish the Axis default WSDL using RPC/encoded style. Despite these minor limitations we have created simple but very promising test VO workflow using the Sesame name resolver service at CDS Strasbourg, the Hubble SIAP server at the Multi-Mission Archive at Space Telescope (MAST) and the WESIX image cataloging and catalogue cross-referencing service at the University of Pittsburgh. ESO Reflex can also pass files and URIs via the PLASTIC protocol to visualisation tools and has its own viewer for VOTables. We picked these three Web Services to try to set up a realistic and useful ESO Reflex workflow. They also demonstrate ESO Reflex abilities to use many kind of Web Services because each of them requires a different interface. We describe each of these services in turn and comment on how it was used

VirGO: A Visual Browser for the ESO Science Archive Facility

NASA Astrophysics Data System (ADS)

Chéreau, F.

2008-08-01

VirGO is the next generation Visual Browser for the ESO Science Archive Facility developed by the Virtual Observatory (VO) Systems Department. It is a plug-in for the popular open source software Stellarium adding capabilities for browsing professional astronomical data. VirGO gives astronomers the possibility to easily discover and select data from millions of observations in a new visual and intuitive way. Its main feature is to perform real-time access and graphical display of a large number of observations by showing instrumental footprints and image previews, and to allow their selection and filtering for subsequent download from the ESO SAF web interface. It also allows the loading of external FITS files or VOTables, the superimposition of Digitized Sky Survey (DSS) background images, and the visualization of the sky in a `real life' mode as seen from the main ESO sites. All data interfaces are based on Virtual Observatory standards which allow access to images and spectra from external data centers, and interaction with the ESO SAF web interface or any other VO applications supporting the PLASTIC messaging system. The main website for VirGO is at http://archive.eso.org/cms/virgo.

REOSC Delivers the Best Astronomical Mirror in the World to ESO

NASA Astrophysics Data System (ADS)

1999-12-01

On December 14, 1999, REOSC , the Optical Department of the SAGEM Group , finished the polishing of the fourth 8.2-m main mirror for the Very Large Telescope (VLT) of the European Southern Observatory. The mirror was today delivered to ESO at a ceremony at the REOSC factory in Saint Pierre du Perray, just south of Paris. The precision of the form of the mirror that was achieved during the polishing process is 8.5 nanometer (1 nanometer = 1 millionth of a millimetre) over the optical surface. This exceptional value corresponds to an optical resolution (theoretical image sharpness) of 0.03 arcseconds in the visible spectrum. This corresponds to distinguishing two objects separated by only 15 cm at a distance of 1000 km and will allow to detect astronomical objects that are 10,000 million times fainter than what can be perceived with the unaided eye. This impressive measure of quality, achieved by the REOSC teams during much painstaking work, implies that this VLT mirror is the most accurate in the world. In fact, all four 8.2-m VLT main mirrors polished by REOSC are well within the very strict specifications set by ESO, but this is the best of them all. The celebration today is the successful highlight of a contract initiated more than ten years ago, during which REOSC has perfected new polishing and control techniques - innovations improved and developed in a unique workshop dedicated to these giant mirrors. These methods and means are directly applicable to the new generations of segmented mirrors that are now being developed for astronomy and space observations. They are, in this sense, at the foremost front of optical technology. REOSC, the Optical Department of the SAGEM Group , is specialised in the study and realisation of high-precision optics for astronomy, space, defence, science and industry. For earlier information about the work on the VLT mirrors, cf. ESO Press Release 15/95 (13 November 1995). The SAGEM Group is a French high-technology group. It

VirGO: A Visual Browser for the ESO Science Archive Facility

NASA Astrophysics Data System (ADS)

Chéreau, Fabien

2012-04-01

VirGO is the next generation Visual Browser for the ESO Science Archive Facility developed by the Virtual Observatory (VO) Systems Department. It is a plug-in for the popular open source software Stellarium adding capabilities for browsing professional astronomical data. VirGO gives astronomers the possibility to easily discover and select data from millions of observations in a new visual and intuitive way. Its main feature is to perform real-time access and graphical display of a large number of observations by showing instrumental footprints and image previews, and to allow their selection and filtering for subsequent download from the ESO SAF web interface. It also allows the loading of external FITS files or VOTables, the superimposition of Digitized Sky Survey (DSS) background images, and the visualization of the sky in a `real life' mode as seen from the main ESO sites. All data interfaces are based on Virtual Observatory standards which allow access to images and spectra from external data centers, and interaction with the ESO SAF web interface or any other VO applications supporting the PLASTIC messaging system.

ESO's Two Observatories Merge

NASA Astrophysics Data System (ADS)

2005-02-01

, a unique instrument capable of measuring stellar radial velocities with an unsurpassed accuracy better than 1 m/s, making it a very powerful tool for the discovery of extra-solar planets. In addition, astronomers have also access to the 2.2-m ESO/MPG telescope with its Wide Field Imager camera. A new control room, the RITZ (Remote Integrated Telescope Zentrum), allows operating all three ESO telescopes at La Silla from a single place. The La Silla Observatory is also the first world-class observatory to have been granted certification for the International Organization for Standardization (ISO) 9001 Quality Management System. Moreover, the infrastructure of La Silla is still used by many of the ESO member states for targeted projects such as the Swiss 1.2-m Euler telescope and the robotic telescope specialized in the follow-up of gamma-ray bursts detected by satellites, the Italian REM (Rapid Eye Mount). In addition, La Silla is in charge of the APEX (Atacama Pathfinder Experiment) 12-m sub-millimetre telescope which will soon start routine observations at Chajnantor, the site of the future Atacama Large Millimeter Array (ALMA). The APEX project is a collaboration between the Max Planck Society in Germany, Onsala Observatory in Sweden and ESO. ESO also operates Paranal, home of the Very Large Telescope (VLT) and the VLT Interferometer (VLTI). Antu, the first 8.2-m Unit Telescope of the VLT, saw First Light in May 1998, starting what has become a revolution in European astronomy. Since then, the three other Unit Telescopes - Kueyen, Melipal and Yepun - have been successfully put into operation with an impressive suite of the most advanced astronomical instruments. The interferometric mode of the VLT (VLTI) is also operational and fully integrated in the VLT data flow system. In the VLTI mode, one state-of-the-art instrument is already available and another will follow soon. With its remarkable resolution and unsurpassed surface area, the VLT is at the forefront of

Public surveys at ESO

NASA Astrophysics Data System (ADS)

Arnaboldi, Magda; Delmotte, Nausicaa; Hilker, Michael; Hussain, Gaitee; Mascetti, Laura; Micol, Alberto; Petr-Gotzens, Monika; Rejkuba, Marina; Retzlaff, Jörg; Mieske, Steffen; Szeifert, Thomas; Ivison, Rob; Leibundgut, Bruno; Romaniello, Martino

2016-07-01

ESO has a strong mandate to survey the Southern Sky. In this article, we describe the ESO telescopes and instruments that are currently used for ESO Public Surveys, and the future plans of the community with the new wide-field-spectroscopic instruments. We summarize the ESO policies governing the management of these projects on behalf of the community. The on-going ESO Public Surveys and their science goals, their status of completion, and the new projects selected during the second ESO VISTA call in 2015/2016 are discussed. We then present the impact of these projects in terms of current numbers of refereed publications and the scientific data products published through the ESO Science Archive Facility by the survey teams, including the independent access and scientific use of the published survey data products by the astronomical community.

VirGO: A Visual Browser for the ESO Science Archive Facility

NASA Astrophysics Data System (ADS)

Hatziminaoglou, Evanthia; Chéreau, Fabien

2009-03-01

VirGO is the next generation Visual Browser for the ESO Science Archive Facility (SAF) developed in the Virtual Observatory Project Office. VirGO enables astronomers to discover and select data easily from millions of observations in a visual and intuitive way. It allows real-time access and the graphical display of a large number of observations by showing instrumental footprints and image previews, as well as their selection and filtering for subsequent download from the ESO SAF web interface. It also permits the loading of external FITS files or VOTables, as well as the superposition of Digitized Sky Survey images to be used as background. All data interfaces are based on Virtual Observatory (VO) standards that allow access to images and spectra from external data centres, and interaction with the ESO SAF web interface or any other VO applications.

VLT Images the Horsehead Nebula

NASA Astrophysics Data System (ADS)

2002-01-01

Summary A new, high-resolution colour image of one of the most photographed celestial objects, the famous "Horsehead Nebula" (IC 434) in Orion, has been produced from data stored in the VLT Science Archive. The original CCD frames were obtained in February 2000 with the FORS2 multi-mode instrument at the 8.2-m VLT KUEYEN telescope on Paranal (Chile). The comparatively large field-of-view of the FORS2 camera is optimally suited to show this extended object and its immediate surroundings in impressive detail. PR Photo 02a/02 : View of the full field around the Horsehead Nebula. PR Photo 02b/02 : Enlargement of a smaller area around the Horse's "mouth" A spectacular object ESO PR Photo 02a/02 ESO PR Photo 02a/02 [Preview - JPEG: 400 x 485 pix - 63k] [Normal - JPEG: 800 x 970 pix - 896k] [Full-Res - JPEG: 1951 x 2366 pix - 4.7M] ESO PR Photo 02b/02 ESO PR Photo 02b/02 [Preview - JPEG: 400 x 501 pix - 91k] [Normal - JPEG: 800 x 1002 pix - 888k] [Full-Res - JPEG: 1139 x 1427 pix - 1.9M] Caption : PR Photo 02a/02 is a reproduction of a composite colour image of the Horsehead Nebula and its immediate surroundings. It is based on three exposures in the visual part of the spectrum with the FORS2 multi-mode instrument at the 8.2-m KUEYEN telescope at Paranal. PR Photo 02b/02 is an enlargement of a smaller area. Technical information about these photos is available below. PR Photo 02a/02 shows the famous "Horsehead Nebula" , which is situated in the Orion molecular cloud complex. Its official name is Barnard 33 and it is a dust protrusion in the southern region of the dense dust cloud Lynds 1630 , on the edge of the HII region IC 434 . The distance to the region is about 1400 light-years (430 pc). This beautiful colour image was produced from three images obtained with the multi-mode FORS2 instrument at the second VLT Unit Telescope ( KUEYEN ), some months after it had "First Light", cf. PR 17/99. The image files were extracted from the VLT Science Archive Facility and the

Tim de Zeeuw to Become the Next Director General of ESO

NASA Astrophysics Data System (ADS)

2007-01-01

The ESO Council has just appointed Tim de Zeeuw, 50, as the next Director General of ESO, effective as of 1 September 2007, when the current Director General, Catherine Cesarsky will complete her mandate. ESO PR Photo 02/07 ESO PR Photo 03/07 Professor Tim de Zeeuw "ESO is Europe's flagship organisation for ground-based astronomy," said, Richard Wade, President of the ESO Council. "The ESO Council is very pleased that Professor de Zeeuw has accepted the task as its next Director General. He has played a key role over the last few years in developing a strategic vision for ESO, and I have every confidence that he will now lead the organisation in the realisation of that exciting vision." Tim de Zeeuw has an excellent record, both as a highly respected scientist and as a leader of an internationally recognised science institute in the Netherlands. He is Scientific Director of the Leiden Observatory, a research institute in the College of Mathematics and Natural Sciences of Leiden University. Tim de Zeeuw also has considerable experience as regards science policy issues. Catherine Cesarsky, ESO's current Director General commented: "Over the recent years, ESO has developed considerably with more activities and new member states, and with its ambitious project portfolio, ESO is clearly facing an exciting future. I shall be delighted to pass the baton to Tim de Zeeuw, who as a recent Council member is very familiar with our Organisation." "It is a great honour and an exciting challenge to lead this world-class organisation in the years to come in support of one of the most dynamic areas of science today," said de Zeeuw. "I look forward to overseeing the continued upgrading of the Very Large Telescope with the second-generation instrumentation and the completion of the ALMA project, and in particular to help developing the future European Extremely Large Telescope." Tim de Zeeuw's main research interests embrace the formation, structure and dynamics of galaxies

Professor Tim de Zeeuw Takes Up Duty as New ESO Director General

NASA Astrophysics Data System (ADS)

2007-09-01

On 1 September, Tim de Zeeuw became the new ESO Director General, succeeding Catherine Cesarsky. In his first day in office, he kindly agreed to answer a few questions. ESO PR Photo 38/07 ESO PR Video 38/07 Watch the Video! How would you describe the current period for astronomy? Tim de Zeeuw: We are in an extremely exciting time for astronomy and I think this is understood worldwide and not just by astronomers. The technology is now available to look not only at the farthest objects in the Universe, where the light left a long time ago, allowing us to see how the Universe evolved and developed, but we can even detect signatures of planets around other stars, and that answers an age-old question which is a fundamental question in all of science, and really excites the general public. How do you see the role of ESO in this context? Tim de Zeeuw: ESO has a very important role in the context of European and worldwide astronomy because it is one of the leading organisations for ground-based astronomy. You may even say it is the pre-eminent organisation. Therefore, we have both an opportunity and a responsibility to lead the further developments in astronomy. Where do you see ESO developing in the coming years? Tim de Zeeuw: I see three main goals for ESO in the coming years. The first one is to get the best possible science out of the Very Large Telescope, the interferometer and the survey telescopes, all of them on Paranal. The second is to build ALMA, the new observatory at 5 000 metres in the high Andes. Together with our North American and East Asian partners, we need to deliver this on budget and on time, and prepare the European astronomers for leading the science. The third main goal is to design a world-leading Extremely Large Telescope (ELT), which may have a main mirror with a diameter larger than 40 metres and will enable wonderful science. And of course, we don't only want to design it, we also want to construct it. And what about La Silla? Tim de Zeeuw: La

United Kingdom to Join ESO on July 1, 2002

NASA Astrophysics Data System (ADS)

2001-12-01

united European face in astronomy through ESO". The President of the ESO Council, Dr. Arno Freytag , shares this opinion fully. "This is a most important step in the continuing process of European integration. The entry of the UK will of course be very useful to the scientists in that country, but I have no doubt that the benefits will be mutual. With its world-level astronomical and engineering expertise and with one of the most active research communities in Europe, the UK will bring significant intellectual, technical and financial resources to strengthen ESO. I have no doubt that the impressive research that is now being carried out by numerous astronomers with the ESO facilities has been our best advertisement and I am sure that this has had an important effect on the very welcome decision by the UK to join ESO." The UK will pay the usual annual contribution to ESO from the date of its entry. It has also been decided that as an important part of the special contribution to be made on entry, the UK will deliver the VISTA infrared survey telescope to ESO as an in-kind contribution. This wide-field telescope facility is now being constructed in the UK for a consortium of universities and it was decided already last year to place it at Paranal, cf. ESO PR 03/00. It will now become a fully integrated part of the ESO Paranal Observatory providing important survey observations in support of the VLT. Ian Halliday , Chief Executive of PPARC, is "delighted that the negotiations with ESO and subsequent Council meetings have passed this critical decision point. We now expect a straightforward parliamentary process to ratify the intergovernmental treaty. This decision will allow UK astronomers to have access to the world-class VLT telescopes at Paranal. Just as importantly UK Astronomy will have a sound basis for the future ALMA and OWL projects in a European context. This is a major increase in investment in, and capability for, UK Astronomy." Notes [1]: Both ESO and PPARC

Awesome Universe: an exhibition with images that showcase celestial objects as seen by ESO's observatories and associated activities

NASA Astrophysics Data System (ADS)

Marin-Farrona, A. M.

2015-05-01

In September 2013, an ESO exhibition was shown in Santander: ``Awesome Universe -- the Cosmos through the eyes of the European Southern Observatory". Around the exhibition, were proposed several activities: guide tours for children, younger and adults, workshops, film projections... In this way, the exhibition was visited by more than two thousand persons. We must keep in mind that Santander is a small city and its population does not usually take part in outreach activity. With this contribution, we want to teach the way in which it is possible to take advantage of science exhibitions. It made possible to show stunning images that showcase celestial objects as seen by ESO's observatories to the great majority of Santander population, and to awaken their interest in or enthusiasm for science.

Finland to Join ESO

NASA Astrophysics Data System (ADS)

2004-03-01

Finland will become the eleventh member state of the European Southern Observatory. In a ceremony at the ESO Headquarters in Garching on 9 February 2004, an Agreement to this effect was signed by the Finnish Minister of Education and Science, Ms. Tuula Haatainen and the ESO Director General, Dr. Catherine Cesarsky, in the presence of other high officials from Finland and the ESO member states.

Hubble:WFPC2 and ESO:2.2-m Composite Image of 30 Dor Runaway Star

NASA Image and Video Library

2017-12-08

NASA image release May 11, 2010 Hubble Catches Heavyweight Runaway Star Speeding from 30 Doradus Image: Hubble/WFPC2 and ESO/2.2-m Composite Image of 30 Dor Runaway Star A blue-hot star, 90 times more massive than our Sun, is hurtling across space fast enough to make a round trip from Earth to the Moon in merely two hours. Though the speed is not a record-breaker, it is unique to find a homeless star that has traveled so far from its nest. The only way the star could have been ejected from the star cluster where it was born is through a tussle with a rogue star that entered the binary system where the star lived, which ejected the star through a dynamical game of stellar pinball. This is strong circumstantial evidence for stars as massive as 150 times our Sun's mass living in the cluster. Only a very massive star would have the gravitational energy to eject something weighing 90 solar masses. The runaway star is on the outskirts of the 30 Doradus nebula, a raucous stellar breeding ground in the nearby Large Magellanic Cloud. The finding bolsters evidence that the most massive stars in the local universe reside in 30 Doradus, making it a unique laboratory for studying heavyweight stars. 30 Doradus, also called the Tarantula Nebula, is roughly 170,000 light-years from Earth. To learn more about this image go to: www.nasa.gov/mission_pages/hubble/science/runaway-star.html Credit: NASA, ESA, J. Walsh (ST-ECF), and ESO NASA Goddard Space Flight Center is home to the nation's largest organization of combined scientists, engineers and technologists that build spacecraft, instruments and new technology to study the Earth, the sun, our solar system, and the universe.

VizieR Online Data Catalog: KiDS-ESO-DR3 multi-band source catalog (de Jong+, 2017)

NASA Astrophysics Data System (ADS)

de Jong, J. T. A.; Verdoes Kleijn, G. A.; Erben, T.; Hildebrandt, H.; Kuijken, K.; Sikkema, G.; Brescia, M.; Bilicki, M.; Napolitano, N. R.; Amaro, V.; Begeman, K. G.; Boxhoorn, D. R.; Buddelmeijer, H.; Cavuoti, S.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; La Barbera, F.; Longo, G.; McFarland, J. P.; Nakajima, R.; Paolillo, M.; Puddu, E.; Radovich, M.; Rifatto, A.; Tortora, C; Valentijn, E. A.; Vellucci, C.; Vriend, W-J.; Amon, A.; Blake, C.; Choi, A.; Fenech, Conti I.; Herbonnet, R.; Heymans, C.; Hoekstra, H.; Klaes, D.; Merten, J.; Miller, L.; Schneider, P.; Viola, M.

2017-04-01

KiDS-ESO-DR3 contains a multi-band source catalogue encompassing all publicly released tiles, a total of 440 survey tiles including the coadded images, weight maps, masks and source lists of 292 survey tiles of KiDS-ESO-DR3, adding to the 148 tiles released previously (50 in KiDS-ESO-DR1 and 98 in KiDS-ESO-DR2). (1 data file).

UK Announces Intention to Join ESO

NASA Astrophysics Data System (ADS)

2000-11-01

Summary The Particle Physics and Astronomy Research Council (PPARC) , the UK's strategic science investment agency, today announced that the government of the United Kingdom is making funds available that provide a baseline for this country to join the European Southern Observatory (ESO) . The ESO Director General, Dr. Catherine Cesarsky , and the ESO Community warmly welcome this move towards fuller integration in European astronomy. "With the UK as a potential member country of ESO, our joint opportunities for front-line research and technology will grow significantly", she said. "This announcement is a clear sign of confidence in ESO's abilities, most recently demonstrated with the construction and operation of the unique Very Large Telescope (VLT) on Paranal. Together we will look forward with confidence towards new, exciting projects in ground-based astronomy." It was decided earlier this year to place the 4-m UK Visible and Infrared Survey Telescope (VISTA) at Paranal, cf. ESO Press Release 03/00. Following negotiations between ESO and PPARC, a detailed proposal for the associated UK/ESO Agreement with the various entry modalities will now be presented to the ESO Council for approval. Before this Agreement can enter into force, the ESO Convention and associated protocols must also be ratified by the UK Parliament. Research and key technologies According to the PPARC press release, increased funding for science, announced by the UK government today, will enable UK astronomers to prepare for the next generation of telescopes and expand their current telescope portfolio through membership of the European Southern Observatory (ESO). The uplift to its baseline budget will enable PPARC to enter into final negotiations for UK membership of the ESO. This will ensure that UK astronomers, together with their colleagues in the ESO member states, are actively involved in global scale preparations for the next generation of astronomy facilities. among these are ALMA

Spain to Join ESO

NASA Astrophysics Data System (ADS)

2006-03-01

On 13 February, at a ceremony in Madrid, an agreement was signed by the Spanish Minister of Education and Science, Mrs. María Jesús San Segundo, and the ESO Director General, Dr. Catherine Cesarsky, affirming their commitment to securing Spanish membership of ESO.

ESO takes the public on an astronomical journey "Around the World in 80 Telescopes"

NASA Astrophysics Data System (ADS)

2009-03-01

A live 24-hour free public video webcast, "Around the World in 80 Telescopes", will take place from 3 April 09:00 UT/GMT to 4 April 09:00 UT/GMT, chasing day and night around the globe to let viewers "visit" some of the most advanced astronomical telescopes on and off the planet. The webcast, organised by ESO for the International Year of Astronomy 2009 (IYA2009), is the first time that so many large observatories have been linked together for a public event. ESO PR Photo 13a/09 Map of Participating Observatories ESO PR Photo 13b/09 100 Hours of Astronomy logo Viewers will see new images of the cosmos, find out what observatories in their home countries or on the other side of the planet are discovering, send in questions and messages, and discover what astronomers are doing right now. Participating telescopes include those at observatories in Chile such as ESO's Very Large Telescope and La Silla, the Hawaii-based telescopes Gemini North and Keck, the Anglo-Australian Telescope, telescopes in the Canary Islands, the Southern African Large Telescope, space-based telescopes such as the NASA/ESA Hubble Space Telescope, ESA XMM-Newton and Integral, and many more. "Around the World in 80 Telescopes" will take viewers to every continent, including Antarctica! The webcast production will be hosted at ESO's headquarters near Munich, Germany, with live internet streaming by Ustream.tv. Anyone with a web browser supporting Adobe Flash will be able to follow the show, free of charge, from the website www.100hoursofastronomy.org and be a part of the project by sending messages and questions. The video player can be freely embedded on other websites. TV stations, web portals and science centres can also use the high quality feed. Representatives of the media who wish to report from the "front-line" and interview the team should get in touch. "Around the World in 80 Telescopes" is a major component of the 100 Hours of Astronomy (100HA), a Cornerstone project of the International

ESO unveils an amazing, interactive, 360-degree panoramic view of the entire night sky

NASA Astrophysics Data System (ADS)

2009-09-01

The first of three images of ESO's GigaGalaxy Zoom project - a new magnificent 800-million-pixel panorama of the entire sky as seen from ESO's observing sites in Chile - has just been released online. The project allows stargazers to explore and experience the Universe as it is seen with the unaided eye from the darkest and best viewing locations in the world. This 360-degree panoramic image, covering the entire celestial sphere, reveals the cosmic landscape that surrounds our tiny blue planet. This gorgeous starscape serves as the first of three extremely high-resolution images featured in the GigaGalaxy Zoom project, launched by ESO within the framework of the International Year of Astronomy 2009 (IYA2009). GigaGalaxy Zoom features a web tool that allows users to take a breathtaking dive into our Milky Way. With this tool users can learn more about many different and exciting objects in the image, such as multicoloured nebulae and exploding stars, just by clicking on them. In this way, the project seeks to link the sky we can all see with the deep, "hidden" cosmos that astronomers study on a daily basis. The wonderful quality of the images is a testament to the splendour of the night sky at ESO's sites in Chile, which are the most productive astronomical observatories in the world. The plane of our Milky Way Galaxy, which we see edge-on from our perspective on Earth, cuts a luminous swath across the image. The projection used in GigaGalaxy Zoom place the viewer in front of our Galaxy with the Galactic Plane running horizontally through the image - almost as if we were looking at the Milky Way from the outside. From this vantage point, the general components of our spiral galaxy come clearly into view, including its disc, marbled with both dark and glowing nebulae, which harbours bright, young stars, as well as the Galaxy's central bulge and its satellite galaxies. The painstaking production of this image came about as a collaboration between ESO, the renowned

ESO Receives Computerworld Honors Program 21st Century Achievement Award in Science Category

NASA Astrophysics Data System (ADS)

2005-06-01

In a ceremony held in Washington, D.C. (USA) on June 6, 2005, ESO, the European Organisation for Astronomical Research in the southern Hemisphere, received the coveted 21st Century Achievement Award from the Computerworld Honors Program for its visionary use of information technology in the Science category. Sybase, a main database server vendor and member of the Chairmen's Committee, nominated ESO's Data Flow System in recognition of its contributions to the global information technology revolution and its positive impact on society. The citations reads: "ESO has revolutionized the operations of ground-based astronomical observatories with a new end-to-end data flow system, designed to improve the transmission and management of astronomical observations and data over transcontinental distances." This year's awards, in 10 categories, were presented at a gala event at the National Building Museum, attended by over 250 guests, including leaders of the information technology industry, former award recipients, judges, scholars, and diplomats representing many of the 54 countries from which the 17-year-old program's laureates have come. "The Computerworld Honors Program 21st Century Achievement Awards are presented to companies from around the world whose visionary use of information technology promotes positive social, economic and educational change," said Bob Carrigan, president and CEO of Computerworld and chairman of the Chairmen's Committee of the Computerworld Honors Program. "The recipients of these awards are the true heroes of the information age and have been appropriately recognized by the leading IT industry chairmen as true revolutionaries in their fields." ESO PR Photo 18/05 ESO PR Photo 18/05 ESO Receives the Award in the Science Category [Preview - JPEG: 400 x 496 pix - 53k] [Normal - JPEG: 800 x 992 pix - 470k] [Full Res - JPEG: 1250 x 1550 pix - 1.1M] Caption: ESO PR Photo 18/05: Receiving the Computerworld 21st Century Achievement Award for Science

Report on the 2009 ESO Fellows Symposium

NASA Astrophysics Data System (ADS)

Emsellem, Eric; West, Michael; Leibundgut, Bruno

2009-09-01

The fourth ESO Fellows Symposium took place in Garching from 8-10 June 2009. This year's symposium brought together 28 ESO Fellows from Chile and Germany to meet their colleagues from across the ocean, discuss their research and provide feedback on ESO's Fellowship programme. This year's symposium also included training workshops to enhance the practical skills of ESO Fellows in today's competitive job market.

Detecting esophageal disease with second-generation capsule endoscopy: initial evaluation of the PillCam ESO 2.

PubMed

Gralnek, I M; Adler, S N; Yassin, K; Koslowsky, B; Metzger, Y; Eliakim, R

2008-04-01

Esophageal capsule endoscopy (ECE) provides an alternative, minimally invasive modality for evaluating the esophagus. This study evaluates the performance and test characteristics of a second-generation esophageal capsule endoscope, the PillCam ESO 2. Adults with known or suspected esophageal disease were included. Using the simplified ingestion procedure, each patient underwent capsule endoscopy with the PillCam ESO 2. Following ECE, esophagogastroduodenoscopy (EGD) was performed on the same day by an investigator who was blinded to the results of the ECE. In random order, capsule endoscopy videos were read and interpreted by the study investigator blinded to EGD results. 28 patients (19 men, 9 women; mean age 53.3 years) were included. In 82 % of the patients, at least 75 % of the Z line was visualized by the PillCam ESO 2. A per-lesion analysis demonstrated that the PillCam ESO 2 had definitive results in 30/43 lesions (69.8 %) and EGD in 29/43 (67.4 %), P value = 0.41. Compared with EGD for detecting suspected Barrett's esophagus and esophagitis, the PillCam ESO 2 had a sensitivity of 100 % and a specificity of 74 %, and a sensitivity of 80 % and a specificity of 87 %, respectively. The PillCam ESO 2 demonstrated 86 % agreement with EGD in describing the Z line (kappa statistic 0.68). The modified ingestion protocol provided excellent cleansing, with bubbles/saliva having no or only a minor effect on Z line images in 86 % of cases. The PillCam ESO 2 demonstrated excellent visualization of the Z line. Compared with standard EGD, the PillCam ESO 2 had good test characteristics with high rates of detection of suspected Barrett's esophagus and esophagitis. This study provides indirect validation of the simplified ingestion procedure. The PillCam ESO 2 acquires high quality esophageal images, performs safely, and should be able to replace the current PillCam ESO.

Blockbuster starring ESO Paranal opens tomorrow

NASA Astrophysics Data System (ADS)

2008-10-01

The 22nd James Bond adventure is due for release tomorrow, 31 October 2008, in the UK and a week later in the rest of the world. A key location in the movie is the Residencia, the hotel for astronomers and staff at ESO's Paranal Observatory. Blockbuster starring ESO Paranal opens tomorrow ESO PR Photo 38/08 The James Bond "Quantum of Solace" filmmakers Quantum of Solace is the latest film in one of most successful movie franchises -- that of renowned 007 Agent James Bond of the British Secret Service MI6. The agent "on Her Majesty's secret service" is once again played by Daniel Craig. Key scenes of the movie were filmed at Paranal, the home of ESO's Very Large Telescope, and the most advanced optical telescope in the world. Usually occupied by no more than 100 astronomers, engineers and technicians, Paranal welcomed the 300-strong film crew for several days of shooting at the end of March 2008. The crew travelled from their hotel base in Antofagasta for up to two hours each morning to reach the filming locations. "We are delighted to have a movie like this filmed at Paranal and it was extremely good to see how careful the crew were with the surroundings and how mindful they were of the fact that they were in an operating, working observatory", says Tim de Zeeuw, ESO Director General. "Paranal is a unique observatory in a unique setting and it is no real surprise that it plays a major part in a James Bond movie", he adds. The filmmakers were mostly interested in filming exterior scenes at the Paranal Residencia, the accommodation for staff operating the Very Large Telescope. In the movie, the Residencia is supposedly the "Perla de Las Dunas", a unique hotel in the desert. Cerro Paranal is a 2600 m high mountain in the Chilean Atacama Desert, perhaps the driest on Earth. The high altitude site and extreme dryness make excellent conditions for astronomical observations. To make it possible for people to live and work here, a hotel, or Residencia, was built at the

High Resolution HST Images of Pluto and Charon

NASA Astrophysics Data System (ADS)

1994-05-01

the physical properties of the two bodies, first of all their composition, surface structure and possible atmospheres. The analysis of data from a facility as complex as the Hubble Space Telescope is very demanding, and involves experts in many different fields: planetary astronomy, instrument technology, numerical image restoration, and spacecraft engineering. It is therefore not surprising that this investigation is expected to last a long time yet. However, while still in its preliminary stages, it already now appears to indicate the presence of areas of different reflectivity on the surface of Pluto. By a comparison of HST images obtained at two different wavelengths (i.e., in ultraviolet and visual light), the team members hope that it will become possible to construct rough maps of the planetary surface and perhaps also to answer the long-standing question of whether or not there is an atmosphere around Pluto. Notes: [1] This investigation is carried out at the Space Telescope European Coordinating Facility, which is located at the European Southern Observatory as part of a collaboration with the European Space Agency, and also involves other institutes in Europe and the U.S.A. The team of astronomers is headed by Rudolf Albrecht (ST-ECF), and includes Hans-Martin Adorf and Richard Hook (ST-ECF), Alessandra Gemmo and Olivier Hainaut (ESO), Cesare Barbieri and Gabriele Corrain (Osservatorio Astronomico di Padova, Italy), Chris Blades, Perry Greenfield and William Sparks (Space Telescope Science Institute, Baltimore, Maryland, U.S.A.) and David Tholen (Institute for Astronomy, University of Hawaii, U.S.A.). [2] The photo is available to the media from the ESO Information Service (address below) as ESO PR Photo 09/94-1 and from the Space Telescope Science Institute (Baltimore, USA) as STSci-PR94-17. Reproductions should be credited to NASA, ESA and ESO. Figure Caption Hubble Portrait of the "Double Planet" Pluto & Charon This is the clearest view yet of the distant

ESO Observations of New Moon of Jupiter

NASA Astrophysics Data System (ADS)

2000-08-01

" this object and "secure" its orbit. Recovery of S/1999 J 1 at La Silla Jupiter and its moons would again become visible in the early morning hours in late July with telescopes in the southern hemisphere. By a fortunate coincidence, observing time for observations of comets and asteroids had been allocated to Brett Gladman and his collaborators at two ESO telescopes in exactly this period. Just before sunrise on July 25, he used the Wide Field Imager (WFI) on the MPG/ESO 2.2-m telescope at La Silla to search for S/1999 J 1 . This camera has a comparatively large field-of-view, about 0.5 x 0.5 deg 2 , or about the size of the full moon. This was comfortably larger than the estimated uncertainty in the object's predicted position at the time of the observation. And indeed, S/1999 J 1 was spotted not too far from that location, weakly visible in the glare of the nearby waning moon. Detailed observations of S/1999 J 1 at Paranal Only three days later, in the early morning hours of July 28, the small object was again imaged, this time from the 8.2-m VLT ANTU telescope at Paranal. Brett Gladman and Hermann Boehnhardt , now knowing exactly where to look in the sky, used the FORS-1 multi-mode instrument to obtain exposures of S/1999 J 1 through several optical filters. The great light-collecting power of this telescope resulted in excellent images while S/1999 J 1 was moving across the sky, cf. PR Photos 19a-b/00 . These observations definitively confirmed the "recovery" of the object and also provided an accurate determination of its brightness and colour, cf. IAU Circular 7472 , published on August 3. From accurate positional measurements on these exposures and the earlier ones from La Silla, Gareth Williams of the Minor Planet Center was able to substantially improve the computation of the orbit of S/1999 J 1 around Jupiter. It was found ( IAU Circular 7469 ) to move in a somewhat elliptical orbit around Jupiter with a period of just over 2 years (768 days) and at a mean

Open House at the ESO Headquarters

NASA Astrophysics Data System (ADS)

Madsen, C.

2006-12-01

On 15 October, the ESO Headquarters opened its doors to the public as part of the All-Campus Open House organised in connection with the inauguration of the extension of the underground line U6 from Munich to the Garching campus. The day was blessed with clear skies and plenty of sunshine, and a large number of citizens took advantage of the opportunity to visit the campus. The estimated number of visitors at ESO was close to 3000 people, a record number. Another record was set by the number of ESO staff who, in anticipation of the high num-ber of guests, volunteered to spend their Sunday at work to explain what ESO is doing and why it is important.

Hubble and ESO's VLT provide unique 3D views of remote galaxies

NASA Astrophysics Data System (ADS)

2009-03-01

Astronomers have obtained exceptional 3D views of distant galaxies, seen when the Universe was half its current age, by combining the twin strengths of the NASA/ESA Hubble Space Telescope's acute eye, and the capacity of ESO's Very Large Telescope to probe the motions of gas in tiny objects. By looking at this unique "history book" of our Universe, at an epoch when the Sun and the Earth did not yet exist, scientists hope to solve the puzzle of how galaxies formed in the remote past. ESO PR Photo 10a/09 A 3D view of remote galaxies ESO PR Photo 10b/09 Measuring motions in 3 distant galaxies ESO PR Video 10a/09 Galaxies in collision For decades, distant galaxies that emitted their light six billion years ago were no more than small specks of light on the sky. With the launch of the Hubble Space Telescope in the early 1990s, astronomers were able to scrutinise the structure of distant galaxies in some detail for the first time. Under the superb skies of Paranal, the VLT's FLAMES/GIRAFFE spectrograph (ESO 13/02) -- which obtains simultaneous spectra from small areas of extended objects -- can now also resolve the motions of the gas in these distant galaxies (ESO 10/06). "This unique combination of Hubble and the VLT allows us to model distant galaxies almost as nicely as we can close ones," says François Hammer, who led the team. "In effect, FLAMES/GIRAFFE now allows us to measure the velocity of the gas at various locations in these objects. This means that we can see how the gas is moving, which provides us with a three-dimensional view of galaxies halfway across the Universe." The team has undertaken the Herculean task of reconstituting the history of about one hundred remote galaxies that have been observed with both Hubble and GIRAFFE on the VLT. The first results are coming in and have already provided useful insights for three galaxies. In one galaxy, GIRAFFE revealed a region full of ionised gas, that is, hot gas composed of atoms that have been stripped of

ESO Reflex: A Graphical Workflow Engine for Data Reduction

NASA Astrophysics Data System (ADS)

Hook, R.; Romaniello, M.; Péron, M.; Ballester, P.; Gabasch, A.; Izzo, C.; Ullgrén, M.; Maisala, S.; Oittinen, T.; Solin, O.; Savolainen, V.; Järveläinen, P.; Tyynelä, J.

2008-08-01

Sampo {http://www.eso.org/sampo} (Hook et al. 2005) is a project led by ESO and conducted by a software development team from Finland as an in-kind contribution to joining ESO. The goal is to assess the needs of the ESO community in the area of data reduction environments and to create pilot software products that illustrate critical steps along the road to a new system. Those prototypes will not only be used to validate concepts and understand requirements but will also be tools of immediate value for the community. Most of the raw data produced by ESO instruments can be reduced using CPL {http://www.eso.org/cpl} recipes: compiled C programs following an ESO standard and utilizing routines provided by the Common Pipeline Library. Currently reduction recipes are run in batch mode as part of the data flow system to generate the input to the ESO VLT/VLTI quality control process and are also made public for external users. Sampo has developed a prototype application called ESO Reflex {http://www.eso.org/sampo/reflex/} that integrates a graphical user interface and existing data reduction algorithms. ESO Reflex can invoke CPL-based recipes in a flexible way through a dedicated interface. ESO Reflex is based on the graphical workflow engine Taverna {http://taverna.sourceforge.net} that was originally developed by the UK eScience community, mostly for work in the life sciences. Workflows have been created so far for three VLT/VLTI instrument modes ( VIMOS/IFU {http://www.eso.org/instruments/vimos/}, FORS spectroscopy {http://www.eso.org/instruments/fors/} and AMBER {http://www.eso.org/instruments/amber/}), and the easy-to-use GUI allows the user to make changes to these or create workflows of their own. Python scripts and IDL procedures can be easily brought into workflows and a variety of visualisation and display options, including custom product inspection and validation steps, are available.

Signing of ESO-Poland Accession Agreement

NASA Astrophysics Data System (ADS)

2014-12-01

An agreement was signed by Professor Lena Kolarska-Bobińska, the Polish Minister of Science and Higher Education, and the ESO Director General Tim de Zeeuw in Warsaw on 28 October 2014 that will lead to the country joining ESO. The signing of the agreement followed its unanimous approval by the ESO Council during an extraordinary meeting on 8 October 2014. Poland will be welcomed as a new Member State, following subsequent ratification of the accession agreement by the Polish Parliament. Tim de Zeeuw’s speech at this ceremony is reproduced below.

President of Czech Republic visits ESO's Paranal Observatory

NASA Astrophysics Data System (ADS)

2011-04-01

On 6 April 2011, the ESO Paranal Observatory was honoured with a visit from the President of the Czech Republic, Václav Klaus, and his wife Livia Klausová, who also took the opportunity to admire Cerro Armazones, the future site of the planned E-ELT. The distinguished visitor was shown the technical installations at the observatory, and was present when the dome of one of the four 8.2-metre Unit Telescopes of ESO's Very Large Telescope opened for a night's observing at Cerro Paranal, the world's most advanced visible-light observatory. "I'm delighted to welcome President Klaus to the Paranal Observatory and to show him first-hand the world-leading astronomical facility that ESO has designed, has built, and operates for European astronomy," said ESO's Director General, Tim de Zeeuw. President Klaus replied, "I am very impressed by the remarkable technology that ESO has built here in the heart of the desert. Czech astronomers are already making good use of these facilities and we look forward to having Czech industry and its scientific community contribute to the future E-ELT." From the VLT platform, the President had the opportunity to admire Cerro Armazones as well as other spectacular views of Chile's Atacama Desert surrounding Paranal. Adjacent to Cerro Paranal, Armazones has been chosen as the site for the future E-ELT (see eso1018). ESO is seeking approval from its governing bodies by the end of 2011 for the go-ahead for the 1-billion euro E-ELT. Construction is expected to begin in 2012 and the start of operations is planned for early in the next decade. President Klaus was accompanied by the Minister of Foreign Affairs of the Czech Republic, Karel Schwarzenberg, the Czech Ambassador in Chile, Zdenek Kubánek, dignitaries of the government, and a Czech industrial delegation. The group was hosted at Paranal by the ESO Director General, Tim de Zeeuw, the ESO Representative in Chile, Massimo Tarenghi, the Director of Operations, Andreas Kaufer, and Jan Palous

ESO Reflex: a graphical workflow engine for data reduction

NASA Astrophysics Data System (ADS)

Hook, Richard; Ullgrén, Marko; Romaniello, Martino; Maisala, Sami; Oittinen, Tero; Solin, Otto; Savolainen, Ville; Järveläinen, Pekka; Tyynelä, Jani; Péron, Michèle; Ballester, Pascal; Gabasch, Armin; Izzo, Carlo

ESO Reflex is a prototype software tool that provides a novel approach to astronomical data reduction by integrating a modern graphical workflow system (Taverna) with existing legacy data reduction algorithms. Most of the raw data produced by instruments at the ESO Very Large Telescope (VLT) in Chile are reduced using recipes. These are compiled C applications following an ESO standard and utilising routines provided by the Common Pipeline Library (CPL). Currently these are run in batch mode as part of the data flow system to generate the input to the ESO/VLT quality control process and are also exported for use offline. ESO Reflex can invoke CPL-based recipes in a flexible way through a general purpose graphical interface. ESO Reflex is based on the Taverna system that was originally developed within the UK life-sciences community. Workflows have been created so far for three VLT/VLTI instruments, and the GUI allows the user to make changes to these or create workflows of their own. Python scripts or IDL procedures can be easily brought into workflows and a variety of visualisation and display options, including custom product inspection and validation steps, are available. Taverna is intended for use with web services and experiments using ESO Reflex to access Virtual Observatory web services have been successfully performed. ESO Reflex is the main product developed by Sampo, a project led by ESO and conducted by a software development team from Finland as an in-kind contribution to joining ESO. The goal was to look into the needs of the ESO community in the area of data reduction environments and to create pilot software products that illustrate critical steps along the road to a new system. Sampo concluded early in 2008. This contribution will describe ESO Reflex and show several examples of its use both locally and using Virtual Observatory remote web services. ESO Reflex is expected to be released to the community in early 2009.

First Images from VLT Science Verification Programme

NASA Astrophysics Data System (ADS)

1998-09-01

morning of September 1 when the telescope was returned to the Commissioning Team that has since continued its work. The FORS instrument is now being installed and the first images from this facility are expected shortly. Observational circumstances During the two-week SV period, a total of 154 hours were available for astronomical observations. Of these, 95 hours (62%) were used to collect scientific data, including calibrations, e.g. flat-fielding and photometric standard star observations. 15 hours (10%) were spent to solve minor technical problems, while another 44 hours (29%) were lost due to adverse meteorological conditions (clouds or wind exceeding 15 m/sec). The amount of telescope technical downtime is very small at this moment of the UT1 commissioning. This fact provides an impressive indication of high technical reliability that has been achieved and which will be further consolidated during the next months. The meteorological conditions that were encountered at Paranal during this period were unfortunately below average, when compared to data from the same calendar period in earlier years. There was an excess of bad seeing and fewer good seeing periods than normal; see, however, ESO PR Photo 35c/98 with 0.26 arcsec image quality. Nevertheless, the measured image quality on the acquired frames was often better than the seeing measured outside the enclosure by the Paranal seeing monitor. Part of this very positive effect is due to "active field stabilization" , now performed during all observations by rapid motion (10 - 70 times per second) of the 1.1-m secondary mirror of beryllium (M2) and compensating for the "twinkling" of stars. Science Verification data soon to be released A great amount of valuable data was collected during the SV programme. The available programme time was distributed as follows: Hubble Deep Field - South [HDF-S; NICMOS and STIS Fields] (37.1 hrs); Lensed QSOs (3.2 hrs); High-z Clusters (6.2 hrs); Host Galaxies of Gamma-Ray Bursters (2

ESO Demonstration Project with the NRAO 12-m Antenna

NASA Astrophysics Data System (ADS)

Heald, R.; Karban, R.

2000-03-01

During the months of September through November 1999, an ALMA joint demonstration project between the European Southern Observatory (ESO) and the National Radio Astronomy Observatory (NRAO) was carried out in Socorro/New Mexico. During this period, Robert Karban (ESO) and Ron Heald (NRAO) worked together on the ESO Demonstration Project. The project integrated ESO software and existing NRAO software (a prototype for the future ALMA control software) to control the motion of the Kitt Peak 12-m antenna. ESO software from the VLT provided the operator interface and coordinate transformation software, while Pat Wallace's TPOINT provided the pointing- model software.

ESO & NOT photometric monitoring of the Cloverleaf quasar

NASA Astrophysics Data System (ADS)

Ostensen, R.; Remy, M.; Lindblad, P. O.; Refsdal, S.; Stabell, R.; Surdej, J.; Barthel, P. D.; Emanuelsen, P. I.; Festin, L.; Gosset, E.; Hainaut, O.; Hakala, P.; Hjelm, M.; Hjorth, J.; Hutsemekers, D.; Jablonski, M.; Kaas, A. A.; Kristen, H.; Larsson, S.; Magain, P.; Pettersson, B.; Pospieszalska-Surdej, A.; Smette, A.; Teuber, J.; Thomsen, B.; van Drom, E.

1997-12-01

The Cloverleaf quasar, H1413+117, has been photometrically monitored at ESO (La Silla, Chile) and with the NOT (La Palma, Spain) during the period 1987--1994. All good quality CCD frames have been successfully analysed using two independent methods (i.e. an automatic image decomposition technique and an interactive CLEAN algorithm). The photometric results from the two methods are found to be very similar, and they show that the four lensed QSO images vary significantly in brightness (by up to 0.45 mag), nearly in parallel. The lightcurve of the $D$ component presents some slight departures from the general trend which are very likely caused by micro-lensing effects. Upper limits, at the 99% confidence level, of 150 days on the absolute value for the time delays between the photometric lightcurves of this quadruply imaged variable QSO, are derived. This is unfortunately too large to constrain the lens model but there is little doubt that a better sampling of the lightcurves should allow to accurately derive these time delays. Pending a direct detection of the lensing galaxy (position and redshift), this system thus constitutes another good candidate for a direct and independent determination of the Hubble parameter. Based on observations collected at the European Southern Observatory (La Silla, Chile) and with the Nordic Optical Telescope (La Palma, Spain). Table 1. Logbook for the ESO and NOT observations together with photometric results for the Cloverleaf quasar. This long table can be accessed on the WWW at the URL address: http://vela.astro.ulg.ac.be/grav_lens/glp_homepage.html}

Infrared Images of an Infant Solar System

NASA Astrophysics Data System (ADS)

2002-05-01

ESO Telescopes Detect a Strange-Looking Object Summary Using the ESO 3.5-m New Technology Telescope and the Very Large Telescope (VLT) , a team of astronomers [1] have discovered a dusty and opaque disk surrounding a young solar-type star in the outskirts of a dark cloud in the Milky Way. It was found by chance during an unrelated research programme and provides a striking portrait of what our Solar System must have looked like when it was in its early infancy. Because of its striking appearance, the astronomers have nicknamed it the "Flying Saucer" . The new object appears to be a perfect example of a very young star with a disk in which planets are forming or will soon form, and located far away from the usual perils of an active star-forming environment . Most other young stars, especially those that are born in dense regions, run a serious risk of having their natal dusty disks destroyed by the blazing radiation of their more massive and hotter siblings in these clusters. The star at the centre of the "Flying Saucer", seems destined to live a long and quiet life at the centre of a planetary system , very much like our own Sun. This contributes to making it a most interesting object for further studies with the VLT and other telescopes. The mass of the observed disk of gas and dust is at least twice that of the planet Jupiter and its radius measures about 45 billion km, or 5 times the size of the orbit of Neptune. PR Photo 12a/02 : The "Flying Saucer" object photographed with NTT/SOFI. PR Photo 12b/02 : VLT/ISAAC image of this object. PR Photo 12c/02 : Enlargement of VLT/ISAAC image . Circumstellar Disks and Planets Planets form in dust disks around young stars. This is a complex process of which not all stages are yet fully understood but it begins when small dust particles collide and stick to each other. For this reason, observations of such dust disks, in particular those that appear as extended structures (are "resolved"), are very important for our

Pricing Employee Stock Options (ESOs) with Random Lattice

NASA Astrophysics Data System (ADS)

Chendra, E.; Chin, L.; Sukmana, A.

2018-04-01

Employee Stock Options (ESOs) are stock options granted by companies to their employees. Unlike standard options that can be traded by typical institutional or individual investors, employees cannot sell or transfer their ESOs to other investors. The sale restrictions may induce the ESO’s holder to exercise them earlier. In much cited paper, Hull and White propose a binomial lattice in valuing ESOs which assumes that employees will exercise voluntarily their ESOs if the stock price reaches a horizontal psychological barrier. Due to nonlinearity errors, the numerical pricing results oscillate significantly so they may lead to large pricing errors. In this paper, we use the random lattice method to price the Hull-White ESOs model. This method can reduce the nonlinearity error by aligning a layer of nodes of the random lattice with a psychological barrier.

Some non-atlas work at ESO Sky Atlas Laboratory.

NASA Astrophysics Data System (ADS)

Madsen, C.

The ESO Sky Atlas Laboratory (SAL) was set up in 1972 with the aim of producing the ESO Quick Blue Survey and later the joint ESO/SERC Survey of the Southern Sky. With the establishment of a Scientific Group, it became apparent that ESO had additional photographic needs, the fullfilment of which was also entrusted to SAL. Thus, in the course of the years, the "Photographic Section" evolved as a subdivision of the Sky Atlas Laboratory.

ESO Welcomes Finland as Eleventh Member State

NASA Astrophysics Data System (ADS)

Cesarsky, C.

2004-09-01

In early July, Finland joined ESO as the eleventh member state, following the completion of the formal accession procedure. Before this event, however, Finland and ESO had been in contact for a long time. Under an agreement with Sweden, Finnish astronomers had for quite a while enjoyed access to the SEST at La Silla. Finland had also been a very active participant in ESO's educational activities since they began in 1993. It became clear, that science and technology, as well as education, were priority areas for the Finnish government.

Hundred metre virtual telescope captures unique detailed colour image

NASA Astrophysics Data System (ADS)

2009-02-01

A team of French astronomers has captured one of the sharpest colour images ever made. They observed the star T Leporis, which appears, on the sky, as small as a two-storey house on the Moon [1]. The image was taken with ESO's Very Large Telescope Interferometer (VLTI), emulating a virtual telescope about 100 metres across and reveals a spherical molecular shell around an aged star. ESO PR Photo 06a/09 The star T Leporis as seen with VLTI ESO PR Photo 06b/09 The star T Leporis to scale ESO PR Photo 06c/09 A virtual 100-metre telescope ESO PR Photo 06d/09 The orbit of Theta1 Orionis C ESO PR Video 06a/09 Zoom-in onto T Leporis "This is one of the first images made using near-infrared interferometry," says lead author Jean-Baptiste Le Bouquin. Interferometry is a technique that combines the light from several telescopes, resulting in a vision as sharp as that of a giant telescope with a diameter equal to the largest separation between the telescopes used. Achieving this requires the VLTI system components to be positioned to an accuracy of a fraction of a micrometre over about 100 metres and maintained so throughout the observations -- a formidable technical challenge. When doing interferometry, astronomers must often content themselves with fringes, the characteristic pattern of dark and bright lines produced when two beams of light combine, from which they can model the physical properties of the object studied. But, if an object is observed on several runs with different combinations and configurations of telescopes, it is possible to put these results together to reconstruct an image of the object. This is what has now been done with ESO's VLTI, using the 1.8-metre Auxiliary Telescopes. "We were able to construct an amazing image, and reveal the onion-like structure of the atmosphere of a giant star at a late stage of its life for the first time," says Antoine Mérand, member of the team. "Numerical models and indirect data have allowed us to imagine the

ESO imaging survey: optical follow-up of 12 selected XMM-Newton fields

NASA Astrophysics Data System (ADS)

Dietrich, J. P.; Miralles, J.-M.; Olsen, L. F.; da Costa, L.; Schwope, A.; Benoist, C.; Hambaryan, V.; Mignano, A.; Motch, C.; Rité, C.; Slijkhuis, R.; Tedds, J.; Vandame, B.; Watson, M. G.; Zaggia, S.

2006-04-01

This paper presents the data recently released for the XMM-Newton/WFI survey carried out as part of the ESO Imaging Survey (EIS) project. The aim of this survey is to provide optical imaging follow-up data in BVRI for identification of serendipitously detected X-ray sources in selected XMM-Newton fields. In this paper, fully calibrated individual and stacked images of 12 fields as well as science-grade catalogs for the 8 fields located at high-galactic latitude are presented. These products were created, calibrated and released using the infrastructure provided by the EIS Data Reduction system and its associated EIS/MVM image processing engine, both of which are briefly described here. The data covers an area of ~3 square degrees for each of the four passbands. The median seeing as measured in the final stacked images is 0.94 arcsec, ranging from 0.60 arcsec and 1.51 arcsec. The median limiting magnitudes (AB system, 2´´ aperture, 5σ detection limit) are 25.20, 24.92, 24.66, and 24.39 mag for B-, V-, R-, and I-band, respectively. When only the 8 high-galactic latitude fields are included these become 25.33, 25.05, 25.36, and 24.58 mag, in good agreement with the planned depth of the survey. Visual inspection of images and catalogs, comparison of statistics derived from the present data with those obtained by other authors and model predictions, as well as direct comparison of the results obtained from independent reductions of the same data, demonstrate the science-grade quality of the automatically produced final images and catalogs. These survey products, together with their logs, are available to the community for science exploitation in conjunction with their X-ray counterparts. Preliminary results from the X-ray/optical cross-correlation analysis show that about 61% of the detected X-ray point sources in deep XMM-Newton exposures have at least one optical counterpart within 2´´ radius down to R ≃ 25 mag, 50% of which are so faint as to require VLT

The Cosmic Christmas Ghost - Two Stunning Pictures of Young Stellar Clusters

NASA Astrophysics Data System (ADS)

2005-12-01

Just like Charles Dickens' Christmas Carol takes us on a journey into past, present and future in the time of only one Christmas Eve, two of ESO' s telescopes captured various stages in the life of a star in a single image. ESO PR Photo 42a/05 shows the area surrounding the stellar cluster NGC 2467, located in the southern constellation of Puppis (" The Stern" ). With an age of a few million years at most, it is a very active stellar nursery, where new stars are born continuously from large clouds of dust and gas. The image, looking like a colourful cosmic ghost or a gigantic celestial Mandrill [1] , contains the open clusters Haffner 18 (centre) and Haffner 19 (middle right: it is located inside the smaller pink region - the lower eye of the Mandrill), as well as vast areas of ionised gas. The bright star at the centre of the largest pink region on the bottom of the image is HD 64315, a massive young star that is helping shaping the structure of the whole nebular region. ESO PR Photo 42a/05 was taken with the Wide-Field Imager camera at the 2.2m MPG/ESO telescope located at La Silla, in Chile. Another image of the central part of this area is shown as ESO PR Photo 42b/05. It was obtained with the FORS2 instrument at ESO' s Very Large Telescope on Cerro Paranal, also in Chile. ESO PR Photo 42b/05 zooms in on the open stellar cluster Haffner 18, perfectly illustrating three different stages of this process of star formation: In the centre of the picture, Haffner 18, a group of mature stars that have already dispersed their birth nebulae, represents the completed product or immediate past of the star formation process. Located at the bottom left of this cluster, a very young star, just come into existence and, still surrounded by its birth cocoon of gas, provides insight into the very present of star birth. Finally, the dust clouds towards the right corner of the image are active stellar nurseries that will produce more new stars in the future. Haffner 18 contains

First Image and Spectrum of a Dark Matter Object

NASA Astrophysics Data System (ADS)

2001-12-01

galaxy, such as the Large Magellanic Cloud (LMC), then the gravitational field of the MACHO will bend the light from the distant star and focus it into our telescopes. The MACHO is acting as a gravitational lens, increasing the brightness of the background star for the short time it takes for the MACHO to pass by. Depending on the mass of the MACHO and its distance from Earth, this period of brightening can last days, weeks or months. The form and duration of the brightening caused by the MACHO - the microlensing "light curve" - can be predicted by theory and searched for as a clear signal of the presence of MACHO Dark Matter. MACHOs are described as "microlenses" since they are much smaller than other known cases of gravitational lensing, such as those observed around clusters of galaxies, cf. ESO PR 19/98. Observations of microlensing events have been done on many occasions with ESO telescope with intersting results, e.g., the recent detection of a corona of a distant star in the Milky Way ( ESO PR 17/01 ). The MACHO Project Astronomers from the Lawrence Livermore National Laboratory , the Center for Particle Astrophysics in the United States and the Australian National University joined forces to form the "MACHO Project" in 1991. This team [2] used a dedicated telescope at the Mount Stromlo Observatory in Australia to monitor the brightness of more than 10 million stars in the Large Magellanic Cloud (LMC) over a period of eight years. The team discovered their first gravitational lensing event in 1993 and have now published approximately twenty instances of microlenses in the direction of the Magellanic Clouds. These results demonstrate that there is a population of MACHO objects in and around the Milky Way galaxy that could comprise as much as 50% of the Milky Way total (baryonic/normal-matter) Dark Matter content. Hubble obtains the first direct image of a MACHO ESO PR Photo 35a/01 ESO PR Photo 35a/01 [Preview - JPEG: 400 x 387 pix - 36k] [Normal - JPEG: 800 x 774

Britain Approaches ESO about Installation of Major New Telescope at Paranal

NASA Astrophysics Data System (ADS)

2000-02-01

The Executive Board of the UK Visible and Infrared Survey Telescope (VISTA) project announced today [1] that it is aiming at the installation of a new and powerful astronomical telescope at the ESO Paranal Observatory (Chile). This 4-metre telescope is a specialised wide-angle facility equipped with powerful cameras and efficient detectors that will enable it to obtain deep images of large sky areas in short time. These survey observations will be made in several wavebands in the optical and, in particular, the near-infrared region of the electromagnetic spectrum. VISTA will become the largest and most effective telescope of its type when it enters into operation in 2004. It is a project of a consortium of 18 UK universities [2]. Construction is expected to start in spring 2000. Funding of the project was announced in May 1999, as one of the first allocations from the "Joint Infrastructure Fund (JIF)", an initiative of the UK Government's Department of Trade and Industry, the Wellcome Trust, and the Higher Education Funding Council for England. ESO's Director General, Dr. Catherine Cesarsky , is very pleased with this decision. She received a mandate from the ESO Council in December 1999 to negotiate a contract with the UK Particle Physics and Astronomy Research Council (PPARC) , acting on behalf of the VISTA Executive Board, for the installation of VISTA at Paranal and now looks forward to settle the associated legal and operational details with her British counterparts at good pace. "The installation of VISTA at Paranal will be of great benefit to all European astronomers", she says. "The placement of a survey telescope of this size next to ESO's VLT, the world's largest optical telescope, opens a plethora of exciting opportunities for joint research projects. Deep observations with VISTA, especially in infrared wavebands, will provide a most valuable, first census of large regions of space. This will most certainly lead to the discoveries of many new and

ESO Telescope Designer Raymond Wilson Wins Prestigious Kavli Award for Astrophysics

NASA Astrophysics Data System (ADS)

2010-06-01

Raymond Wilson, whose pioneering optics research at ESO made today's giant telescopes possible thanks to "active optics" technology, has been awarded the 2010 Kavli Prize in astrophysics. The founder and original leader of the Optics and Telescopes Group at ESO, Wilson shares the million-dollar prize with two American scientists, Jerry Nelson and Roger Angel. The biennial prize, presented by the Norwegian Academy of Science and Letters, the Kavli Foundation, and the Norwegian Ministry of Education and Research, was instituted in 2008 and is given to researchers who significantly advance knowledge in the fields of nanoscience, neuroscience, and astrophysics, acting as a complement to the Nobel Prize. The award is named for and funded by Fred Kavli, the Norwegian entrepreneur and phi­lanthropist who later founded the Kavlico Corpora­tion in the US - today one of the world's largest suppliers of sensors for aeronautic, automotive and industrial applications. Wilson, who joined ESO in 1972, strived to achieve optical perfection, developing the concept of active optics as a way to enhance the size of telescopic primary mirrors. It is the size of these mirrors that determines the ability of a telescope to gather light and study faint and distant objects. Before active optics, mirrors over six metres in diameter were impossible, being too heavy, costly, and likely to bend from gravity and temperature changes. The use of active optics, which preserves optimal image quality by continually adjusting the mirror's shape during observations, made lighter, thinner so-called "meniscus mirrors" possible. Wilson first led the implementation of active optics in the revolutionary New Technology Telescope at ESO's La Silla Observatory, and continued to develop and improve the technology until his retirement in 1993. Since then, active optics have become a standard part of modern astronomy, applied in every big telescope including ESO's Very Large Telescope (VLT), a telescope array

ESO Science Outreach Network in Poland during 2011-2013

NASA Astrophysics Data System (ADS)

Czart, Krzysztof

2014-12-01

ESON Poland works since 2010. One of the main tasks of the ESO Science Outreach Network (ESON) is translation of various materials at ESO website, as well as contacts with journalists. We support also science festivals, conferences, contests, exhibitions, astronomy camps and workshops and other educational and outreach activities. During 2011-2013 we supported events like ESO Astronomy Camp 2013, ESO Industry Days in Warsaw, Warsaw Science Festival, Torun Festival of Science and Art, international astronomy olympiad held in Poland and many others. Among big tasks there was also translation of over 60 ESOcast movies.

ESO telbib: Linking In and Reaching Out

NASA Astrophysics Data System (ADS)

Grothkopf, U.; Meakins, S.

2015-04-01

Measuring an observatory's research output is an integral part of its science operations. Like many other observatories, ESO tracks scholarly papers that use observational data from ESO facilities and uses state-of-the-art tools to create, maintain, and further develop the Telescope Bibliography database (telbib). While telbib started out as a stand-alone tool mostly used to compile lists of papers, it has by now developed into a multi-faceted, interlinked system. The core of the telbib database is links between scientific papers and observational data generated by the La Silla Paranal Observatory residing in the ESO archive. This functionality has also been deployed for ALMA data. In addition, telbib reaches out to several other systems, including ESO press releases, the NASA ADS Abstract Service, databases at the CDS Strasbourg, and impact scores at Altmetric.com. We illustrate these features to show how the interconnected telbib system enhances the content of the database as well as the user experience.

The ESA/ESO/NASA Photoshop FITS Liberator 3: Have your say on new features

NASA Astrophysics Data System (ADS)

Nielsen, L. H.; Christensen, L. L.; Hurt, R. L.; Nielsen, K.; Johansen, T.

2008-06-01

The popular, free ESA/ESO/NASA Photoshop FITS Liberator image processing software (a plugin for Adobe Photoshop) is about to get simpler, faster and more user-friendly! Here we would like to solicit inputs from the community of users.

Hubble Space Telescope Scattered-light Imaging and Modeling of the Edge-on Protoplanetary Disk ESO-Hα 569

NASA Astrophysics Data System (ADS)

Wolff, Schuyler G.; Perrin, Marshall D.; Stapelfeldt, Karl; Duchêne, Gaspard; Ménard, Francois; Padgett, Deborah; Pinte, Christophe; Pueyo, Laurent; Fischer, William J.

2017-12-01

We present new Hubble Space Telescope (HST) Advanced Camera for Surveys observations and detailed models for a recently discovered edge-on protoplanetary disk around ESO-Hα 569 (a low-mass T Tauri star in the Cha I star-forming region). Using radiative transfer models, we probe the distribution of the grains and overall shape of the disk (inclination, scale height, dust mass, flaring exponent, and surface/volume density exponent) by model fitting to multiwavelength (F606W and F814W) HST observations together with a literature-compiled spectral energy distribution. A new tool set was developed for finding optimal fits of MCFOST radiative transfer models using the MCMC code emcee to efficiently explore the high-dimensional parameter space. It is able to self-consistently and simultaneously fit a wide variety of observables in order to place constraints on the physical properties of a given disk, while also rigorously assessing the uncertainties in those derived properties. We confirm that ESO-Hα 569 is an optically thick nearly edge-on protoplanetary disk. The shape of the disk is well-described by a flared disk model with an exponentially tapered outer edge, consistent with models previously advocated on theoretical grounds and supported by millimeter interferometry. The scattered-light images and spectral energy distribution are best fit by an unusually high total disk mass (gas+dust assuming a ratio of 100:1) with a disk-to-star mass ratio of 0.16.

Obituary: ESO Astronomer, Alphonse Florsch (Zeekoegat 1962)

NASA Astrophysics Data System (ADS)

Swanepoel, Eric

2015-10-01

In June 1962 Alphonse Florsch, his wife Marguerite and their two sons Bruno (7) and Nicolas (5), came from France to work at the European Southern Observatory (ESO) at Zeekoegat (Florsch 2005-2006). This was during the time of site testing to find the best location for ESO.

ESO Council Decides to Continue VLT Project at Paranal

NASA Astrophysics Data System (ADS)

1994-08-01

The Council [1] of the European Southern Observatory has met in extraordinary session at the ESO Headquarters in Garching near Munich on August 8 and 9, 1994. The main agenda items were concerned with the recent developments around ESO's relations with the host state, the Republic of Chile, as well as the status of the organisation's main project, the 16-metre equivalent Very Large Telescope (VLT) which will become the world's largest optical telescope. Council had decided to hold this special meeting [2] because of various uncertainties that have arisen in connection with the implementation of the VLT Project at Cerro Paranal, approx. 130 kilometres south of Antofagasta, capital of the II Region in Chile. Following continued consultations at different levels within the ESO member states and after careful consideration of all aspects of the current situation - including various supportive actions by the Chilean Government as well as the incessive attacks against this international organisation from certain sides reported in the media in that country - Council took the important decision to continue the construction of the VLT Observatory at Paranal, while at the same time requesting the ESO Management to pursue the ongoing studies of alternative solutions. THE COUNCIL DECISIONS In particular, the ESO Council took note of recent positive developments which have occurred since the May 1994 round of discussions with the Chilean authorities in Santiago. The confirmation of ESO's immunities as an International Organization in Chile, contained in a number of important statements and documents, is considered a significant step by the Chilean Government to insure to ESO the unhindered erection and later operation of the VLT on Paranal. Under these circumstances and in order to maintain progress on the VLT project, the ESO Council authorized the ESO Management to continue the on-site work at Paranal. Council also took note of the desire expressed by the Chilean Government

Thirty-Seven Years of Service with ESO!

NASA Astrophysics Data System (ADS)

Breysacher, J.

2002-12-01

On December 1st, 2002, after thirty- seven years of service, first in Chile and then in Garching, Ms. Christa Euler will leave ESO to enjoy a welldeserved retirement. Among the current staff, she is probably the only person who started her career at ESO just four years after the Organization was founded.

ESO Helps Antofagasta Region after the Earthquake

NASA Astrophysics Data System (ADS)

2007-11-01

On November 14 at 12:41 local time, a major earthquake with magnitude 7.7 on the Richter scale affected the north of Chile. The epicentre was located 35 km from the city of Tocopilla and 170 km of Antofagasta. Two persons died and tens were injured, while buildings were damaged in several cities. In the Maria Elena-Tocopilla area, several thousand homes were destroyed or damaged. In an act of solidarity with the local community and its authorities, ESO immediately announced a donation of 30 millions Chilean pesos (around 40,000 euros) to Antofagasta's Regional Government to support reconstruction in the Region II. ESO and its staff have been shocked by the earthquake and its impact on local communities, especially on the people of Tocopilla. The ESO Representation in Chile formally contacted the regional authorities to explore with them possible ways to collaborate in this difficult moment. In addition, many of ESO staff are personally cooperating with the victims, under the coordination of Cruz Roja, the organisation currently in charge of implementing individual efforts.

The ESO Survey of Non-Publishing Programmes

NASA Astrophysics Data System (ADS)

Patat, F.; Boffin, H. M. J.; Bordelon, D.; Grothkopf, U.; Meakins, S.; Mieske, S.; Rejkuba, M.

2017-12-01

One of the classic ways to measure the success of a scientific facility is the publication return, which is defined as the refereed papers produced per unit of allocated resources (for example, telescope time or proposals). The recent studies by Sterzik et al. (2015, 2016) have shown that 30–50 % of the programmes allocated time at ESO do not produce a refereed publication. While this may be inherent to the scientific process, this finding prompted further investigation. For this purpose, ESO conducted a Survey of Non-Publishing Programmes (SNPP) within the activities of the Time Allocation Working Group, similar to the monitoring campaign that was recently implemented at ALMA (Stoehr et al., 2016). The SNPP targeted 1278 programmes scheduled between ESO Periods 78 and 90 (October 2006 to March 2013) that had not published a refereed paper as of April 2016. The poll was launched on 6 May 2016, remained open for four weeks, and returned 965 valid responses. This article summarises and discusses the results of this survey, the first of its kind at ESO.

A multimedia electronic patient record (ePR) system for image-assisted minimally invasive spinal surgery.

PubMed

Documet, Jorge; Le, Anh; Liu, Brent; Chiu, John; Huang, H K

2010-05-01

This paper presents the concept of bridging the gap between diagnostic images and image-assisted surgical treatment through the development of a one-stop multimedia electronic patient record (ePR) system that manages and distributes the real-time multimodality imaging and informatics data that assists the surgeon during all clinical phases of the operation from planning Intra-Op to post-care follow-up. We present the concept of this multimedia ePR for surgery by first focusing on image-assisted minimally invasive spinal surgery as a clinical application. Three clinical phases of minimally invasive spinal surgery workflow in Pre-Op, Intra-Op, and Post-Op are discussed. The ePR architecture was developed based on the three-phased workflow, which includes the Pre-Op, Intra-Op, and Post-Op modules and four components comprising of the input integration unit, fault-tolerant gateway server, fault-tolerant ePR server, and the visualization and display. A prototype was built and deployed to a minimally invasive spinal surgery clinical site with user training and support for daily use. A step-by-step approach was introduced to develop a multimedia ePR system for imaging-assisted minimally invasive spinal surgery that includes images, clinical forms, waveforms, and textual data for planning the surgery, two real-time imaging techniques (digital fluoroscopic, DF) and endoscope video images (Endo), and more than half a dozen live vital signs of the patient during surgery. Clinical implementation experiences and challenges were also discussed.

Vaccination with NY-ESO-1 overlapping peptides mixed with Picibanil OK-432 and montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

PubMed

Wada, Hisashi; Isobe, Midori; Kakimi, Kazuhiro; Mizote, Yu; Eikawa, Shingo; Sato, Eiichi; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Yamasaki, Makoto; Miyata, Hiroshi; Matsushita, Hirokazu; Udono, Heiichiro; Seto, Yasuyuki; Yamada, Kazuhiro; Nishikawa, Hiroyoshi; Pan, Linda; Venhaus, Ralph; Oka, Mikio; Doki, Yuichiro; Nakayama, Eiichi

2014-01-01

We conducted a clinical trial of an NY-ESO-1 cancer vaccine using 4 synthetic overlapping long peptides (OLP; peptides #1, 79-108; #2, 100-129; #3, 121-150; and #4, 142-173) that include a highly immunogenic region of the NY-ESO-1 molecule. Nine patients were immunized with 0.25 mg each of three 30-mer and a 32-mer long NY-ESO-1 OLP mixed with 0.2 KE Picibanil OK-432 and 1.25 mL Montanide ISA-51. The primary endpoints of this study were safety and NY-ESO-1 immune responses. Five to 18 injections of the NY-ESO-1 OLP vaccine were well tolerated. Vaccine-related adverse events observed were fever and injection site reaction (grade 1 and 2). Two patients showed stable disease after vaccination. An NY-ESO-1-specific humoral immune response was observed in all patients and an antibody against peptide #3 (121-150) was detected firstly and strongly after vaccination. NY-ESO-1 CD4 and CD8 T-cell responses were elicited in these patients and their epitopes were identified. Using a multifunctional cytokine assay, the number of single or double cytokine-producing cells was increased in NY-ESO-1-specific CD4 and CD8 T cells after vaccination. Multiple cytokine-producing cells were observed in PD-1 (-) and PD-1 (+) CD4 T cells. In conclusion, our study indicated that the NY-ESO-1 OLP vaccine mixed with Picibanil OK-432 and Montanide ISA-51 was well tolerated and elicited NY-ESO-1-specific humoral and CD4 and CD8 T-cell responses in immunized patients.

Overview of ESO Large Single Dish Study

NASA Astrophysics Data System (ADS)

Testi, Leonardo

2018-01-01

In this talk I will briefly summarize the motivation, methodology and outcome of the ESO Submm Single Dish Strategy WG. The WG was established by the ESO Director for Science and completed its work at the end of 2015. I will summarize the status of the report recommendations, which, among other things, led to the organization of the AtLAST workshop.

The VANDELS ESO spectroscopic survey

NASA Astrophysics Data System (ADS)

McLure, R. J.; Pentericci, L.; Cimatti, A.; Dunlop, J. S.; Elbaz, D.; Fontana, A.; Nandra, K.; Amorin, R.; Bolzonella, M.; Bongiorno, A.; Carnall, A. C.; Castellano, M.; Cirasuolo, M.; Cucciati, O.; Cullen, F.; De Barros, S.; Finkelstein, S. L.; Fontanot, F.; Franzetti, P.; Fumana, M.; Gargiulo, A.; Garilli, B.; Guaita, L.; Hartley, W. G.; Iovino, A.; Jarvis, M. J.; Juneau, S.; Karman, W.; Maccagni, D.; Marchi, F.; Mármol-Queraltó, E.; Pompei, E.; Pozzetti, L.; Scodeggio, M.; Sommariva, V.; Talia, M.; Almaini, O.; Balestra, I.; Bardelli, S.; Bell, E. F.; Bourne, N.; Bowler, R. A. A.; Brusa, M.; Buitrago, F.; Caputi, K. I.; Cassata, P.; Charlot, S.; Citro, A.; Cresci, G.; Cristiani, S.; Curtis-Lake, E.; Dickinson, M.; Fazio, G. G.; Ferguson, H. C.; Fiore, F.; Franco, M.; Fynbo, J. P. U.; Galametz, A.; Georgakakis, A.; Giavalisco, M.; Grazian, A.; Hathi, N. P.; Jung, I.; Kim, S.; Koekemoer, A. M.; Khusanova, Y.; Le Fèvre, O.; Lotz, J. M.; Mannucci, F.; Maltby, D. T.; Matsuoka, K.; McLeod, D. J.; Mendez-Hernandez, H.; Mendez-Abreu, J.; Mignoli, M.; Moresco, M.; Mortlock, A.; Nonino, M.; Pannella, M.; Papovich, C.; Popesso, P.; Rosario, D. P.; Salvato, M.; Santini, P.; Schaerer, D.; Schreiber, C.; Stark, D. P.; Tasca, L. A. M.; Thomas, R.; Treu, T.; Vanzella, E.; Wild, V.; Williams, C. C.; Zamorani, G.; Zucca, E.

2018-05-01

VANDELS is a uniquely-deep spectroscopic survey of high-redshift galaxies with the VIMOS spectrograph on ESO's Very Large Telescope (VLT). The survey has obtained ultra-deep optical (0.48 < λ < 1.0 μm) spectroscopy of ≃2100 galaxies within the redshift interval 1.0 ≤ z ≤ 7.0, over a total area of ≃ 0.2 deg2 centred on the CANDELS UDS and CDFS fields. Based on accurate photometric redshift pre-selection, 85% of the galaxies targeted by VANDELS were selected to be at z ≥ 3. Exploiting the red sensitivity of the refurbished VIMOS spectrograph, the fundamental aim of the survey is to provide the high signal-to-noise ratio spectra necessary to measure key physical properties such as stellar population ages, masses, metallicities and outflow velocities from detailed absorption-line studies. Using integration times calculated to produce an approximately constant signal-to-noise ratio (20 < tint < 80 hours), the VANDELS survey targeted: a) bright star-forming galaxies at 2.4 ≤ z ≤ 5.5, b) massive quiescent galaxies at 1.0 ≤ z ≤ 2.5, c) fainter star-forming galaxies at 3.0 ≤ z ≤ 7.0 and d) X-ray/Spitzer-selected active galactic nuclei and Herschel-detected galaxies. By targeting two extragalactic survey fields with superb multi-wavelength imaging data, VANDELS will produce a unique legacy data set for exploring the physics underpinning high-redshift galaxy evolution. In this paper we provide an overview of the VANDELS survey designed to support the science exploitation of the first ESO public data release, focusing on the scientific motivation, survey design and target selection.

ESO Director General to Become President of AUI

NASA Astrophysics Data System (ADS)

1998-11-01

The appointment of Professor Riccardo Giacconi , Director General of the European Southern Observatory (ESO) since January 1, 1993, to the Presidency of Associated Universities, Inc. ( AUI ) in the USA, has been jointly announced by Professor Paul C. Martin, Chair of AUI's Board of Trustees and Mr. Henrik Grage, President of the ESO Council. Professor Giacconi will assume this new position at the end of his term at ESO as of July 1, 1999. AUI is a not-for-profit science management corporation that operates the National Radio Astronomy Observatory ( NRAO) under a Cooperative Agreement with the National Science Foundation (NSF). Corporate headquarters are located in Washington, D.C. The President is its chief executive officer. Nine northeastern universities joined in founding AUI in 1946: Columbia University, Cornell University, Harvard University, The Johns Hopkins University, Massachusetts Institute of Technology, the University of Pennsylvania, Princeton University, the University of Rochester, and Yale University. Over the years, AUI has taken on a broad national character with a diversified Board of Trustees from universities and other institutions across the United States. ESO is an intergovernmental organization, at present with the following member countries: Belgium, Denmark, France, Germany, Italy, The Netherlands, Sweden and Switzerland. Portugal has an agreement with ESO aiming at full membership. ESO was founded in 1962 to establish and operate an astronomical observatory in the southern hemisphere and to promote and organize co-operation in astronomical research in Europe. While the ESO Headquarters are situated in Europe, the observing facilities are located in Chile (South America). The organization's main administrative and technical departments are located at the ESO Headquarters, in Garching near Munich, Germany. They include a number of highly specialized facilities, e.g. the optical, infrared, detector and instrumentation laboratories, all

A multimedia Electronic Patient Record (ePR) system for Image-Assisted Minimally Invasive Spinal Surgery

PubMed Central

Documet, Jorge; Le, Anh; Liu, Brent; Chiu, John; Huang, HK

2009-01-01

Purpose This paper presents the concept of bridging the gap between diagnostic images and image-assisted surgical treatment through the development of a one-stop multimedia electronic patient record (ePR) system that manages and distributes the real-time multimodality imaging and informatics data that assists the surgeon during all clinical phases of the operation from planning Intra-Op to post-care follow-up. We present the concept of this multimedia ePR for surgery by first focusing on Image-Assisted Minimally Invasive Spinal Surgery as a clinical application. Methods Three clinical Phases of Minimally Invasive Spinal Surgery workflow in Pre-Op, Intra-Op, and Post Op are discussed. The ePR architecture was developed based on the three-phased workflow, which includes the Pre-Op, Intra-Op, and Post-Op modules and four components comprising of the input integration unit, fault-tolerant gateway server, fault-tolerant ePR server, and the visualization and display. A prototype was built and deployed to a Minimally Invasive Spinal Surgery clinical site with user training and support for daily use. Summary A step-by step approach was introduced to develop a multi-media ePR system for Imaging-Assisted Minimally Invasive Spinal Surgery that includes images, clinical forms, waveforms, and textual data for planning the surgery, two real-time imaging techniques (digital fluoroscopic, DF) and endoscope video images (Endo), and more than half a dozen live vital signs of the patient during surgery. Clinical implementation experiences and challenges were also discussed. PMID:20033507

ESO Astronomers Detect a Galaxy at the Edge of the Universe

NASA Astrophysics Data System (ADS)

1995-09-01

Starlight from the Depths of Time Four European astronomers [1] have taken advantage of the superb imaging quality of the ESO 3.5-metre New Technology Telescope (NTT) at the La Silla observatory, to detect a galaxy at an extremely large distance. They conclude that its redshift [2] is z = 4.4; thus, this galaxy is by far the most remote ever detected. In fact, it has taken its light about 90 percent of the age of the Universe to reach us, and we now observe this early object as it appeared, only 1 - 2 billion years [3] after the Universe was created in the Big Bang. Still, the galaxy contains a considerable amount of elements that must have been produced in stars. This proves that stars were formed in normal galaxies, already before this very early epoch. Galaxies in the Very Early Universe Astronomical observations during the past decade indicate that the age of the Universe is probably somewhere between 13 and 17 billion years. It is expected that further studies at the limit of available telescopes during the next years will make it possible to determine this fundamental parameter more accurately. But whatever the actual age, one of the central questions which must answered in order to understand the evolution of the Universe is the time of formation of the first stars and galaxies; its determination is accordingly a prime goal of current cosmological observations. This early process was crucial for the distribution of matter now observed, but how long after the Big Bang did it actually happen? We do not know yet. In order to cast more light on this important question, we must look back to this very early epoch by detecting and measuring objects at the largest possible distances, i.e. at the highest redshifts. However, this is extremely difficult because of the faintness of such objects and so far, progress in this fundamental research field has been slow. An Enriched Hydrogen Cloud at z = 4.4 In 1994, the ESO team obtained a high-resolution, detailed spectrum

ESO science data product standard for 1D spectral products

NASA Astrophysics Data System (ADS)

Micol, Alberto; Arnaboldi, Magda; Delmotte, Nausicaa A. R.; Mascetti, Laura; Retzlaff, Joerg

2016-07-01

The ESO Phase 3 process allows the upload, validation, storage, and publication of reduced data through the ESO Science Archive Facility. Since its introduction, 2 million data products have been archived and published; 80% of them are one-dimensional extracted and calibrated spectra. Central to Phase3 is the ESO science data product standard that defines metadata and data format of any product. This contribution describes the ESO data standard for 1d-spectra, its adoption by the reduction pipelines of selected instrument modes for in-house generation of reduced spectra, the enhanced archive legacy value. Archive usage statistics are provided.

From PACS to Web-based ePR system with image distribution for enterprise-level filmless healthcare delivery.

PubMed

Huang, H K

2011-07-01

The concept of PACS (picture archiving and communication system) was initiated in 1982 during the SPIE medical imaging conference in New Port Beach, CA. Since then PACS has been matured to become an everyday clinical tool for image archiving, communication, display, and review. This paper follows the continuous development of PACS technology including Web-based PACS, PACS and ePR (electronic patient record), enterprise PACS to ePR with image distribution (ID). The concept of large-scale Web-based enterprise PACS and ePR with image distribution is presented along with its implementation, clinical deployment, and operation. The Hong Kong Hospital Authority's (HKHA) integration of its home-grown clinical management system (CMS) with PACS and ePR with image distribution is used as a case study. The current concept and design criteria of the HKHA enterprise integration of the CMS, PACS, and ePR-ID for filmless healthcare delivery are discussed, followed by its work-in-progress and current status.

The Potential of ESO for Asteroseismology

NASA Astrophysics Data System (ADS)

Aerts, Conny

2017-08-01

The research field of asteroseismology is currently undergoing its first revolution. We start with a brief history of how this field of stellar physics evolved from dream to reality, including ESO's role in it. Subsequently, we highlight how asteroseismology can serve various topics in astrophysics and focus on the current status. We discuss recent findings on the rotation and chemical mixing inside stars. Finally, we look at the perspectives of the second and third revolution in this area and highlight how ESO can play an optimal role in it.

New Image of Comet Halley in the Cold

NASA Astrophysics Data System (ADS)

2003-09-01

VLT Observes Famous Traveller at Record Distance Summary Seventeen years after the last passage of Comet Halley , the ESO Very Large Telescope at Paranal (Chile) has captured a unique image of this famous object as it cruises through the outer solar system. It is completely inactive in this cold environment. No other comet has ever been observed this far - 4200 million km from the Sun - or that faint - nearly 1000 million times fainter than what can be perceived with the unaided eye. This observation is a byproduct of a dedicated search [1] for small Trans-Neptunian Objects, a population of icy bodies of which more than 600 have been found during the past decade. PR Photo 27a/03 : VLT image (cleaned) of Comet Halley PR Photo 27b/03 : Sky field in which Comet Halley was observed PR Photo 27c/03 : Combined VLT image with star trails and Comet Halley The Halley image ESO PR Photo 27a/03 ESO PR Photo 27a/03 [Preview - JPEG: 546 x 400 pix - 207k] [Normal - JPEG: 1092 x 800 pix - 614k] [FullRes - JPEG: 1502 x 1100 pix - 1.1M] Caption : PR Photo 27a/03 shows the faint, star-like image of Comet Halley (centre), observed with the ESO Very Large Telescope (VLT) at the Paranal Observatory on March 6-8, 2003. 81 individual exposures from three of the four 8.2-m VLT telescopes with a total exposure time of about 9 hours were combined to show the magnitude 28.2 object. At this time, Comet Halley was about 4200 million km from the Sun (28.06 AU) and 4080 million km (27.26 AU) from the Earth. All images of stars and galaxies in the field were removed during the extensive image processing needed to produce this unique image. Due to the remaining, unavoidable "background noise", it is best to view the comet image from some distance. The field measures 60 x 40 arcsec 2 ; North is up and East is left. Remember Comet Halley - the famous "haired star" that has been observed with great regularity - about once every 76 years - during more than two millennia? Which was visited by an

Koha@ESO Reloaded

NASA Astrophysics Data System (ADS)

Meakins, S.; Grothkopf, U.

2015-04-01

What happened to the ESO library's plan to use the open source software Koha as their new library system? After an intensive migration process, we finally went online in June 2012. We want to share some of our experiences, point out advantages and disadvantages of an open source system and show some highlights of Koha, especially the flexibility the system offers.

Status of Women at ESO: a Pilot Study on ESO Staff Gender Distribution

NASA Astrophysics Data System (ADS)

Primas, F.

2007-06-01

Equal career opportunities require working conditions that make it possible to reconcile family needs and career development. This article describes the goals and main findings of a pilot investigation that has recently been ­carried out at ESO focusing on gender balance issues.

Shaping ESO2020+ Together: Feedback from the Community Poll

NASA Astrophysics Data System (ADS)

Primas, F.; Ivison, R.; Berger, J.-P.; Caselli, P.; De Gregorio-Monsalvo, I.; Alonso Herrero, A.; Knudsen, K. K.; Leibundgut, B.; Moitinho, A.; Saviane, I.; Spyromilio, J.; Testi, L.; Vennes, S.

2015-09-01

A thorough evaluation and prioritisation of the ESO science programme into the 2020+ timeframe took place under the auspices of a working group, comprising astronomers drawn from ESO’s advisory structure and from within ESO. This group reported to ESO’s Scientific Technical Committee, and to ESO Council, concluding the exercise with the publication of a report, “Science Priorities at ESO”. A community poll and a dedicated workshop, held in January 2015, formed part of the information gathering process. The community poll was designed to probe the demographics of the user community, its scientific interests, use of observing facilities and plans for use of future telescopes and instruments, its views on types of observing programmes and on the provision of data processing and archiving. A total of 1775 full responses to the poll were received and an analysis of the results is presented here. Foremost is the importance of regular observing programmes on all ESO observing facilities, in addition to Large Programmes and Public Surveys. There was also a strong community requirement for ESO to process and archive data obtained at ESO facilities. Other aspects, especially those related to future facilities, are more challenging to interpret because of biases related to the distribution of science expertise and favoured wavelength regime amongst the targeted audience. The results of the poll formed a fundamental component of the report and pro-vide useful data to guide the evolution of ESO’s science programme.

Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN.

PubMed

Wahlgren, Nils; Moreira, Tiago; Michel, Patrik; Steiner, Thorsten; Jansen, Olav; Cognard, Christophe; Mattle, Heinrich P; van Zwam, Wim; Holmin, Staffan; Tatlisumak, Turgut; Petersson, Jesper; Caso, Valeria; Hacke, Werner; Mazighi, Mikael; Arnold, Marcel; Fischer, Urs; Szikora, Istvan; Pierot, Laurent; Fiehler, Jens; Gralla, Jan; Fazekas, Franz; Lees, Kennedy R

2016-01-01

The original version of this consensus statement on mechanical thrombectomy was approved at the European Stroke Organisation (ESO)-Karolinska Stroke Update conference in Stockholm, 16-18 November 2014. The statement has later, during 2015, been updated with new clinical trials data in accordance with a decision made at the conference. Revisions have been made at a face-to-face meeting during the ESO Winter School in Berne in February, through email exchanges and the final version has then been approved by each society. The recommendations are identical to the original version with evidence level upgraded by 20 February 2015 and confirmed by 15 May 2015. The purpose of the ESO-Karolinska Stroke Update meetings is to provide updates on recent stroke therapy research and to discuss how the results may be implemented into clinical routine. Selected topics are discussed at consensus sessions, for which a consensus statement is prepared and discussed by the participants at the meeting. The statements are advisory to the ESO guidelines committee. This consensus statement includes recommendations on mechanical thrombectomy after acute stroke. The statement is supported by ESO, European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), and European Academy of Neurology (EAN). © 2016 World Stroke Organization.

Second Announcement - ESO/ST-ECF Workshop on NICMOS and the VLT: A New Era of High-Resolution Near-Infrared Imaging and Spectroscopy - May 26-27, 1998 - Hotel Baia di Nora, Pula, Sardinia, Italy

NASA Astrophysics Data System (ADS)

1998-03-01

ST-ECF and ESO are organising in collaboration with the NICMOS IDT and STScI a workshop on near infrared imaging from space and ground. The purpose of the workshop is to review what has been achieved with the Near Infrared and Multi Object Spectrograph (NICMOS) on board of HST, what can be achieved in the remaining lifetime of the instrument, and how NICMOS observations can be optimised taking into account the availability of IR imaging and spectroscopy on ESO's Very large Telescope (VLT) in the near future. The meeting will be held in May 1998, about one year after science observations started with NICMOS, and about half a year before the Infrared Spectrometer and Array Camera (ISAAC) starts to operate on the VLT. Currently, it is expected that NICMOS will operate until the end of 1998.

ESO Council Visits First VLT Unit Telescope Structure in Milan

NASA Astrophysics Data System (ADS)

1995-12-01

(UT4). Mirrors and Instruments As earlier announced, ESO officially received the first 8.2-metre VLT mirror from REOSC in Paris [3] on November 21. The polishing of the second mirror has already started and, based on the experience gained with the first, it is expected that this work will be accomplished in less time. The third blank is already at REOSC and the fourth will soon be ready at Schott Glaswerke in Mainz (Germany). Following extended studies, and as yet another move towards new technology within the VLT project, it has now been decided to make the 1.2-metre secondary VLT mirrors of beryllium, a very light, exotic metal. The contracting firm is Dornier of the DASA group (Germany). This saves much weight and allows these relatively large mirrors to be efficiently used in the `chopping and tilting' mode needed for observations in the infrared wavelength region as well as for the critical, image-sharpening adaptive optics system. Significant progress has also been achieved on the first astronomical instruments which will be installed at the VLT. The integration of the first two of these, ISAAC and CONICA which will be installed on UT1 in the course of 1997, has already started in the ESO laboratories at the Headquarters in Garching. Important advances have also taken place within the FORS (managed by a consortium of Landessternwarte Heidelberg, Universitaets-Sternwarte Goettingen and Institut fuer Astronomie und Astrophysik der Ludwig Maximilians Universitaet Muenchen) and FUEGOS (Paris Observatory, Meudon Observatory, Toulouse Observatory, Geneva Observatory and Bologna Observatory) projects. More details about these and other VLT instruments will be given in later communications. Notes: [1] The Council of ESO consists of two representatives from each of the eight member states. It is the highest legislative authority of the organisation and normally meets twice a year. This time, Council was invited to Milan by the Director of the Osservatorio di Brera (Milan

Another Look at an Enigmatic New World

NASA Astrophysics Data System (ADS)

2005-02-01

VLT NACO Performs Outstanding Observations of Titan's Atmosphere and Surface On January 14, 2005, the ESA Huygens probe arrived at Saturn's largest satellite, Titan. After a faultless descent through the dense atmosphere, it touched down on the icy surface of this strange world from where it continued to transmit precious data back to the Earth. Several of the world's large ground-based telescopes were also active during this exciting event, observing Titan before and near the Huygens encounter, within the framework of a dedicated campaign coordinated by the members of the Huygens Project Scientist Team. Indeed, large astronomical telescopes with state-of-the art adaptive optics systems allow scientists to image Titan's disc in quite some detail. Moreover, ground-based observations are not restricted to the limited period of the fly-by of Cassini and landing of Huygens. They hence complement ideally the data gathered by this NASA/ESA mission, further optimising the overall scientific return. A group of astronomers [1] observed Titan with ESO's Very Large Telescope (VLT) at the Paranal Observatory (Chile) during the nights from 14 to 16 January, by means of the adaptive optics NAOS/CONICA instrument mounted on the 8.2-m Yepun telescope [2]. The observations were carried out in several modes, resulting in a series of fine images and detailed spectra of this mysterious moon. They complement earlier VLT observations of Titan, cf. ESO Press Photos 08/04 and ESO Press Release 09/04. The highest contrast images ESO PR Photo 04a/05 ESO PR Photo 04a/05 Titan's surface (NACO/VLT) [Preview - JPEG: 400 x 712 pix - 64k] [Normal - JPEG: 800 x 1424 pix - 524k] ESO PR Photo 04b/05 ESO PR Photo 04b/05 Map of Titan's Surface (NACO/VLT) [Preview - JPEG: 400 x 651 pix - 41k] [Normal - JPEG: 800 x 1301 pix - 432k] Caption: ESO PR Photo 04a/05 shows Titan's trailing hemisphere [3] with the Huygens landing site marked as an "X". The left image was taken with NACO and a narrow-band filter

And Then There Were Three...!

NASA Astrophysics Data System (ADS)

2000-01-01

VLT MELIPAL Achieves Successful "First Light" in Record Time This was a night to remember at the ESO Paranal Observatory! For the first time, three 8.2-m VLT telescopes were observing in parallel, with a combined mirror surface of nearly 160 m 2. In the evening of January 26, the third 8.2-m Unit Telescope, MELIPAL ("The Southern Cross" in the Mapuche language), was pointed to the sky for the first time and successfully achieved "First Light". During this night, a number of astronomical exposures were made that served to evaluate provisionally the performance of the new telescope. The ESO staff expressed great satisfaction with MELIPAL and there were broad smiles all over the mountain. The first images ESO PR Photo 04a/00 ESO PR Photo 04a/00 [Preview - JPEG: 400 x 352 pix - 95k] [Normal - JPEG: 800 x 688 pix - 110k] Caption : ESO PR Photo 04a/00 shows the "very first light" image for MELIPAL . It is that of a relatively bright star, as recorded by the Guide Probe at about 21:50 hrs local time on January 26, 2000. It is a 0.1 sec exposure, obtained after preliminary adjustment of the optics during a few iterations with the computer controlled "active optics" system. The image quality is measured as 0.46 arcsec FWHM (Full-Width at Half Maximum). ESO PR Photo 04b/00 ESO PR Photo 04b/00 [Preview - JPEG: 400 x 429 pix - 39k] [Normal - JPEG: 885 x 949 pix - 766k] Caption : ESO PR Photo 04b/00 shows the central region of the Crab Nebula, the famous supernova remnant in the constellation Taurus (The Bull). It was obtained early in the night of "First Light" with the third 8.2-m VLT Unit Telescope, MELIPAL . It is a composite of several 30-sec exposures with the VLT Test Camera in three broad-band filters, B (here rendered as blue; most synchrotron emission), V (green) and R (red; mostly emission from hydrogen atoms). The Crab Pulsar is visible to the left; it is the lower of the two brightest stars near each other. The image quality is about 0.9 arcsec, and is completely

NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432: Rapid and Strong Induction of NY-ESO-1-specific Immune Responses by Poly-ICLC.

PubMed

Takeoka, Tomohira; Nagase, Hirotsugu; Kurose, Koji; Ohue, Yoshihiro; Yamasaki, Makoto; Takiguchi, Shuji; Sato, Eiichi; Isobe, Midori; Kanazawa, Takayuki; Matsumoto, Mitsunobu; Iwahori, Kota; Kawashima, Atsunari; Morimoto-Okazawa, Akiko; Nishikawa, Hiroyoshi; Oka, Mikio; Pan, Linda; Venhaus, Ralph; Nakayama, Eiichi; Mori, Masaki; Doki, Yuichiro; Wada, Hisashi

2017-03-23

We conducted a clinical trial of a cancer vaccine using NY-ESO-1 protein with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose (poly-ICLC) and/or OK-432 against solid tumors. A total of 15 patients were sequentially enrolled in 4 cohorts. Patients in cohort 1 received NY-ESO-1 protein; cohort 2a received NY-ESO-1 protein+OK-432; cohort 2b received NY-ESO-1 protein+poly-ICLC; cohort 3 received NY-ESO-1 protein+OK-432+poly-ICLC with Montanide ISA-51. The endpoints of this trial were safety, NY-ESO-1 immune responses, and clinical response. Vaccine-related adverse events observed were fever and injection-site reaction (grade 1). Two patients showed stable disease after vaccination. NY-ESO-1 antibodies were observed in 4 patients at the baseline (sero-positive) and augmented in all patients after vaccination. Eleven patients showed a conversion of negative antibody responses at baseline to positive after vaccination (seroconversion). The seroconversions were observed in all 11 sero-negative patients by the fourth immunization; in particular, it was observed by the second immunization in patients with poly-ICLC, and these induced antibody responses were stronger than those in patients immunized without poly-ICLC. The number of NY-ESO-1-specific interferon (IFN)γ-producing T cells was increased in patients immunized with poly-ICLC and/or OK-432, and furthermore, the increase of IFNγ-producing CD8 T cells in patients immunized with poly-ICLC was significantly higher than that in patients without poly-ICLC. Nonspecific activations of T-cell or antigen presenting cells were not observed. Our present study showed that poly-ICLC is a promising adjuvant for cancer vaccines.

Titanic Weather Forecasting

NASA Astrophysics Data System (ADS)

2004-04-01

New Detailed VLT Images of Saturn's Largest Moon Optimizing space missions Titan, the largest moon of Saturn was discovered by Dutch astronomer Christian Huygens in 1655 and certainly deserves its name. With a diameter of no less than 5,150 km, it is larger than Mercury and twice as large as Pluto. It is unique in having a hazy atmosphere of nitrogen, methane and oily hydrocarbons. Although it was explored in some detail by the NASA Voyager missions, many aspects of the atmosphere and surface still remain unknown. Thus, the existence of seasonal or diurnal phenomena, the presence of clouds, the surface composition and topography are still under debate. There have even been speculations that some kind of primitive life (now possibly extinct) may be found on Titan. Titan is the main target of the NASA/ESA Cassini/Huygens mission, launched in 1997 and scheduled to arrive at Saturn on July 1, 2004. The ESA Huygens probe is designed to enter the atmosphere of Titan, and to descend by parachute to the surface. Ground-based observations are essential to optimize the return of this space mission, because they will complement the information gained from space and add confidence to the interpretation of the data. Hence, the advent of the adaptive optics system NAOS-CONICA (NACO) [1] in combination with ESO's Very Large Telescope (VLT) at the Paranal Observatory in Chile now offers a unique opportunity to study the resolved disc of Titan with high sensitivity and increased spatial resolution. Adaptive Optics (AO) systems work by means of a computer-controlled deformable mirror that counteracts the image distortion induced by atmospheric turbulence. It is based on real-time optical corrections computed from image data obtained by a special camera at very high speed, many hundreds of times each second (see e.g. ESO Press Release 25/01 , ESO PR Photos 04a-c/02, ESO PR Photos 19a-c/02, ESO PR Photos 21a-c/02, ESO Press Release 17/02, and ESO Press Release 26/03 for earlier NACO

Three novel NY-ESO-1 epitopes bound to DRB1*0803, DQB1*0401 and DRB1*0901 recognized by CD4 T cells from CHP-NY-ESO-1-vaccinated patients.

PubMed

Mizote, Yu; Taniguchi, Taku; Tanaka, Kei; Isobe, Midori; Wada, Hisashi; Saika, Takashi; Kita, Shoichi; Koide, Yukari; Uenaka, Akiko; Nakayama, Eiichi

2010-07-19

Three novel NY-ESO-1 CD4 T cell epitopes were identified using PBMC obtained from patients who were vaccinated with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein (CHP-NY-ESO-1). The restriction molecules were determined by antibody blocking and using various EBV-B cells with different HLA alleles as APC to present peptides to CD4 T cells. The minimal epitope peptides were determined using various N- and C-termini truncated peptides deduced from 18-mer overlapping peptides originally identified for recognition. Those epitopes were DRB1*0901-restricted NY-ESO-1 87-100, DQB1*0401-restricted NY-ESO-1 95-107 and DRB1*0803-restricted NY-ESO-1 124-134. CD4 T cells used to determine those epitope peptides recognized EBV-B cells or DC that were treated with recombinant NY-ESO-1 protein or NY-ESO-1-expressing tumor cell lysate, suggesting that the epitope peptides are naturally processed. These CD4 T cells showed a cytokine profile with Th1 characteristics. Furthermore, NY-ESO-1 87-100 peptide/HLA-DRB1*0901 tetramer staining was observed. Multiple Th1-type CD4 T cell responses are beneficial for inducing effective anti-tumor responses after NY-ESO-1 protein vaccination. (c) 2010 Elsevier Ltd. All rights reserved.

The VANDELS ESO public spectroscopic survey

NASA Astrophysics Data System (ADS)

McLure, R. J.; Pentericci, L.; Cimatti, A.; Dunlop, J. S.; Elbaz, D.; Fontana, A.; Nandra, K.; Amorin, R.; Bolzonella, M.; Bongiorno, A.; Carnall, A. C.; Castellano, M.; Cirasuolo, M.; Cucciati, O.; Cullen, F.; De Barros, S.; Finkelstein, S. L.; Fontanot, F.; Franzetti, P.; Fumana, M.; Gargiulo, A.; Garilli, B.; Guaita, L.; Hartley, W. G.; Iovino, A.; Jarvis, M. J.; Juneau, S.; Karman, W.; Maccagni, D.; Marchi, F.; Mármol-Queraltó, E.; Pompei, E.; Pozzetti, L.; Scodeggio, M.; Sommariva, V.; Talia, M.; Almaini, O.; Balestra, I.; Bardelli, S.; Bell, E. F.; Bourne, N.; Bowler, R. A. A.; Brusa, M.; Buitrago, F.; Caputi, K. I.; Cassata, P.; Charlot, S.; Citro, A.; Cresci, G.; Cristiani, S.; Curtis-Lake, E.; Dickinson, M.; Fazio, G. G.; Ferguson, H. C.; Fiore, F.; Franco, M.; Fynbo, J. P. U.; Galametz, A.; Georgakakis, A.; Giavalisco, M.; Grazian, A.; Hathi, N. P.; Jung, I.; Kim, S.; Koekemoer, A. M.; Khusanova, Y.; Fèvre, O. Le; Lotz, J. M.; Mannucci, F.; Maltby, D. T.; Matsuoka, K.; McLeod, D. J.; Mendez-Hernandez, H.; Mendez-Abreu, J.; Mignoli, M.; Moresco, M.; Mortlock, A.; Nonino, M.; Pannella, M.; Papovich, C.; Popesso, P.; Rosario, D. P.; Salvato, M.; Santini, P.; Schaerer, D.; Schreiber, C.; Stark, D. P.; Tasca, L. A. M.; Thomas, R.; Treu, T.; Vanzella, E.; Wild, V.; Williams, C. C.; Zamorani, G.; Zucca, E.

2018-05-01

VANDELS is a uniquely-deep spectroscopic survey of high-redshift galaxies with the VIMOS spectrograph on ESO's Very Large Telescope (VLT). The survey has obtained ultra-deep optical (0.48 < λ < 1.0 μm) spectroscopy of ≃2100 galaxies within the redshift interval 1.0 ≤ z ≤ 7.0, over a total area of ≃ 0.2 deg2 centred on the CANDELS UDS and CDFS fields. Based on accurate photometric redshift pre-selection, 85% of the galaxies targeted by VANDELS were selected to be at z ≥ 3. Exploiting the red sensitivity of the refurbished VIMOS spectrograph, the fundamental aim of the survey is to provide the high signal-to-noise ratio spectra necessary to measure key physical properties such as stellar population ages, masses, metallicities and outflow velocities from detailed absorption-line studies. Using integration times calculated to produce an approximately constant signal-to-noise ratio (20 < tint < 80 hours), the VANDELS survey targeted: a) bright star-forming galaxies at 2.4 ≤ z ≤ 5.5, b) massive quiescent galaxies at 1.0 ≤ z ≤ 2.5, c) fainter star-forming galaxies at 3.0 ≤ z ≤ 7.0 and d) X-ray/Spitzer-selected active galactic nuclei and Herschel-detected galaxies. By targeting two extragalactic survey fields with superb multi-wavelength imaging data, VANDELS will produce a unique legacy data set for exploring the physics underpinning high-redshift galaxy evolution. In this paper we provide an overview of the VANDELS survey designed to support the science exploitation of the first ESO public data release, focusing on the scientific motivation, survey design and target selection.

Report on the ''ESO Python Boot Camp — Pilot Version''

NASA Astrophysics Data System (ADS)

Dias, B.; Milli, J.

2017-03-01

The Python programming language is becoming very popular within the astronomical community. Python is a high-level language with multiple applications including database management, handling FITS images and tables, statistical analysis, and more advanced topics. Python is a very powerful tool both for astronomical publications and for observatory operations. Since the best way to learn a new programming language is through practice, we therefore organised a two-day hands-on workshop to share expertise among ESO colleagues. We report here the outcome and feedback from this pilot event.

Sharper and Deeper Views with MACAO-VLTI

NASA Astrophysics Data System (ADS)

2003-05-01

"First Light" with Powerful Adaptive Optics System for the VLT Interferometer Summary On April 18, 2003, a team of engineers from ESO celebrated the successful accomplishment of "First Light" for the MACAO-VLTI Adaptive Optics facility on the Very Large Telescope (VLT) at the Paranal Observatory (Chile). This is the second Adaptive Optics (AO) system put into operation at this observatory, following the NACO facility ( ESO PR 25/01 ). The achievable image sharpness of a ground-based telescope is normally limited by the effect of atmospheric turbulence. However, with Adaptive Optics (AO) techniques, this major drawback can be overcome so that the telescope produces images that are as sharp as theoretically possible, i.e., as if they were taken from space. The acronym "MACAO" stands for "Multi Application Curvature Adaptive Optics" which refers to the particular way optical corrections are made which "eliminate" the blurring effect of atmospheric turbulence. The MACAO-VLTI facility was developed at ESO. It is a highly complex system of which four, one for each 8.2-m VLT Unit Telescope, will be installed below the telescopes (in the Coudé rooms). These systems correct the distortions of the light beams from the large telescopes (induced by the atmospheric turbulence) before they are directed towards the common focus at the VLT Interferometer (VLTI). The installation of the four MACAO-VLTI units of which the first one is now in place, will amount to nothing less than a revolution in VLT interferometry . An enormous gain in efficiency will result, because of the associated 100-fold gain in sensitivity of the VLTI. Put in simple words, with MACAO-VLTI it will become possible to observe celestial objects 100 times fainter than now . Soon the astronomers will be thus able to obtain interference fringes with the VLTI ( ESO PR 23/01 ) of a large number of objects hitherto out of reach with this powerful observing technique, e.g. external galaxies. The ensuing high

AO wavefront sensing detector developments at ESO

NASA Astrophysics Data System (ADS)

Downing, Mark; Kolb, Johann; Baade, Dietrich; Iwert, Olaf; Hubin, Norbert; Reyes, Javier; Feautrier, Philippe; Gach, Jean-Luc; Balard, Philippe; Guillaume, Christian; Stadler, Eric; Magnard, Yves

2010-07-01

The detector is a critical component of any Adaptive Optics WaveFront Sensing (AO WFS) system. The required combination of fast frame rate, high quantum efficiency, low noise, large number and size of pixels, and low image lag can often only be met by specialized custom developments. ESO's very active WFS detector development program is described. Key test results are presented for newly developed detectors: a) the e2v L3Vision CCD220 (the fastest/lowest noise AO detector to date) to be deployed soon on 2nd Generation VLT instruments, and b) the MPI-HLL pnCCD with its superb high "red" response. The development of still more advanced laser/natural guide-star WFS detectors is critical for the feasibility of ESO's EELT. The paper outlines: a) the multi-phased development plan that will ensure detectors are available on-time for EELT first-light AO systems, b) results of design studies performed by industry during 2007 including a comparison of the most promising technologies, c) results from CMOS technology demonstrators that were built and tested over the past two years to assess and validate various technologies at the pixel level, their fulfillment of critical requirements (especially read noise and speed), and scalability to full-size. The next step will be towards Scaled-Down Demonstrators (SDD) to retire architecture and process risks. The SDD will be large enough to be used for E-ELT first-light AO WFS systems. For full operability, 30-50 full-scale devices will be needed.

A phase I study of vaccination with NY-ESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

PubMed

Kakimi, Kazuhiro; Isobe, Midori; Uenaka, Akiko; Wada, Hisashi; Sato, Eiichi; Doki, Yuichiro; Nakajima, Jun; Seto, Yasuyuki; Yamatsuji, Tomoki; Naomoto, Yoshio; Shiraishi, Kenshiro; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Oka, Mikio; Pan, Linda; Hoffman, Eric W; Old, Lloyd J; Nakayama, Eiichi

2011-12-15

We conducted a phase I clinical trial of a cancer vaccine using a 20-mer NY-ESO-1f peptide (NY-ESO-1 91-110) that includes multiple epitopes recognized by antibodies, and CD4 and CD8 T cells. Ten patients were immunized with 600 μg of NY-ESO-1f peptide mixed with 0.2 KE Picibanil OK-432 and 1.25 ml Montanide ISA-51. Primary end points of the study were safety and immune response. Subcutaneous injection of the NY-ESO-1f peptide vaccine was well tolerated. Vaccine-related adverse events observed were fever (Grade 1), injection-site reaction (Grade 1 or 2) and induration (Grade 2). Vaccination with the NY-ESO-1f peptide resulted in an increase or induction of NY-ESO-1 antibody responses in nine of ten patients. The sera reacted with recombinant NY-ESO-1 whole protein as well as the NY-ESO-1f peptide. An increase in CD4 and CD8 T cell responses was observed in nine of ten patients. Vaccine-induced CD4 and CD8 T cells responded to NY-ESO-1 91-108 in all patients with various HLA types with a less frequent response to neighboring peptides. The findings indicate that the 20-mer NY-ESO-1f peptide includes multiple epitopes recognized by CD4 and CD8 T cells with distinct specificity. Of ten patients, two with lung cancer and one with esophageal cancer showed stable disease. Our study shows that the NY-ESO-1f peptide vaccine was well tolerated and elicited humoral, CD4 and CD8 T cell responses in immunized patients. Copyright © 2011 UICC.

Cosmic Spider is Good Mother

NASA Astrophysics Data System (ADS)

2006-04-01

Hanging above the Large Magellanic Cloud (LMC) - one of our closest galaxies - in what some describe as a frightening sight, the Tarantula nebula is worth looking at in detail. Also designated 30 Doradus or NGC 2070, the nebula owes its name to the arrangement of its brightest patches of nebulosity that somewhat resemble the legs of a spider. This name, of the biggest spiders on Earth, is also very fitting in view of the gigantic proportions of the celestial nebula - it measures nearly 1,000 light years across! ESO PR Photo 11/06 ESO PR Photo 13b/06 Tarantula's Central Cluster, R136 The Tarantula nebula is the largest emission nebula in the sky and also one of the largest known star-forming regions in all the Milky Way's neighbouring galaxies. Located about 170,000 light-years away, in the southern constellation Dorado (The Swordfish), it can be seen with the unaided eye. As shown in this image obtained with the FORS1 multi-mode instrument on ESO's Very Large Telescope, its structure is fascinatingly complex, with a large number of bright arcs and apparently dark areas in between. Inside the giant emission nebula lies a cluster of young, massive and hot stars, denoted R 136, whose intense radiation and strong winds make the nebula glow, shaping it into the form of a giant arachnid. The cluster is about 2 to 3 million years old, that is, almost from 'yesterday' in the 13.7 billion year history of the Universe. Several of the brighter members in the immediate surroundings of the dense cluster are among the most massive stars known, with masses well above 50 times the mass of our Sun. The cluster itself contains more than 200 massive stars. ESO PR Photo 11/06 ESO PR Photo 13c/06 The Stellar Cluster Hodge 301 In the upper right of the image, another cluster of bright, massive stars is seen. Known to astronomers as Hodge 301, it is about 20 million years old, or about 10 times older than R136. The more massive stars of Hodge 301 have therefore already exploded as

Blasting away a dwarf galaxy: the `tail' of ESO 324-G024

NASA Astrophysics Data System (ADS)

Johnson, Megan C.; Kamphuis, Peter; Koribalski, Bärbel S.; Wang, Jing; Oh, Se-Heon; Hill, Alex S.; O'Sullivan, Shane; Haan, Sebastian; Serra, Paolo

2015-08-01

We present Australia Telescope Compact Array radio data of the dwarf irregular galaxy ESO 324-G024 which is seen in projection against the giant, northern lobe of the radio galaxy Centaurus A (Cen A, NGC 5128). The distorted morphology and kinematics of ESO 324-G024, as observed in the 21 cm spectral line emission of neutral hydrogen, indicate disruptions by external forces. We investigate whether tidal interactions and/or ram pressure stripping are responsible for the formation of the H I tail stretching to the north-east of ESO 324-G024 with the latter being most probable. Furthermore, we closely analyse the sub-structure of Cen A's polarized radio lobes to ascertain whether ESO 324-G024 is located in front, within or behind the northern lobe. Our multiwavelength, multicomponent approach allows us to determine that ESO 324-G024 is most likely behind the northern radio lobe of Cen A. This result helps to constrain the orientation of the lobe, which is likely inclined to our line of sight by approximately 60° if NGC 5128 and ESO 324-G024 are at the same distance.

Fourth Light at Paranal!

NASA Astrophysics Data System (ADS)

2000-09-01

mirror system. At 21:44 hrs (01:44 UT), the Test Camera at the Cassegrain focus within the M1 mirror cell was opened for 30 seconds, with the planetary nebula Hen 2-428 in the field. The resulting "First Light" image was immediately read out and appeared on the computer screen at 21:45:53 hrs (01:45:53 UT). "Not bad! - "Very nice!" were the first, "business-as-usual"-like comments in the room. The zenith distance during this observation was 44° and the image quality was measured as 0.9 arcsec, exactly the same as that registered by the Seeing Monitoring Telescope outside the telescope building. There was some wind. ESO PR Photo 22a/00 ESO PR Photo 22a/00 [Preview - JPEG: 374 x 400 pix - 128k] [Normal - JPEG: 978 x 1046 pix - 728k] Caption : ESO PR Photo 22a/00 shows a colour composite of some of the first astronomical exposures obtained by YEPUN . The object is the planetary nebula Hen 2-428 that is located at a distance of 6,000-8,000 light-years and seen in a dense sky field, only 2° from the main plane of the Milky Way. As other planetary nebulae, it is caused by a dying star (the bluish object at the centre) that shreds its outer layers. The image is based on exposures through three optical filtres: B(lue) (10 min exposure, seeing 0.9 arcsec; here rendered as blue), V(isual) (5 min; 0.9 arcsec; green) and R(ed) (3 min; 0.9 arcsec; red). The field measures 88 x 78 arcsec 2 (1 pixel = 0.09 arcsec). North is to the lower right and East is to the lower left. The 5-day old Moon was about 90° away in the sky that was accordingly bright. The zenith angle was 44°. The ESO staff then proceeded to take a series of three photos with longer exposures through three different optical filtres. They have been combined to produce the image shown in ESO PR Photo 22a/00 . More astronomical images were obtained in sequence, first of the dwarf galaxy NGC 6822 in the Local Group (see PR Photo 22f/00 below) and then of the spiral galaxy NGC 7793 . All 8.2-m telescopes now in operation

News from the ESO Science Archive Facility

NASA Astrophysics Data System (ADS)

Dobrzycki, A.; Arnaboldi, M.; Bierwirth, T.; Boelter, M.; Da Rocha, C.; Delmotte, N.; Forchì, V.; Fourniol, N.; klein Gebbinck, M.; Lange, U.; Mascetti, L.; Micol, A.; Moins, C.; Munte, C.; Pluciennik, C.; Retzlaff, J.; Romaniello, M.; Rosse, N.; Sequeiros, I. V.; Vuong, M.-H.; Zampieri, S.

2015-09-01

ESO Science Archive Facility (SAF) - one of the world's biggest astronomical archives - combines two roles: operational (ingest, tallying, safekeeping and distribution to observers of raw data taken with ESO telescopes and processed data generated both internally and externally) and scientific (publication and delivery of all flavours of data to external users). This paper presents the “State of the SAF.” SAF, as a living entity, is constantly implementing new services and upgrading the existing ones. We present recent and future developments related to the Archive's Request Handler and metadata handling as well as performance and usage statistics and trends. We also discuss the current and future datasets on offer at SAF.

Operating a petabyte class archive at ESO

NASA Astrophysics Data System (ADS)

Suchar, Dieter; Lockhart, John S.; Burrows, Andrew

2008-07-01

The challenges of setting up and operating a Petabyte Class Archive will be described in terms of computer systems within a complex Data Centre environment. The computer systems, including the ESO Primary and Secondary Archive and the associated computational environments such as relational databases will be explained. This encompasses the entire system project cycle, including the technical specifications, procurement process, equipment installation and all further operational phases. The ESO Data Centre construction and the complexity of managing the environment will be presented. Many factors had to be considered during the construction phase, such as power consumption, targeted cooling and the accumulated load on the building structure to enable the smooth running of a Petabyte class Archive.

Europe's Astronomy Teachers Meet at ESO

NASA Astrophysics Data System (ADS)

1994-12-01

European Association for Astronomy Education Formed A joint EU/ESO Workshop (1) on the Teaching of Astronomy in Europe was held at the ESO Headquarters from November 25-30, 1994, under the auspices of the 1994 European Week for Scientific Culture. More than 100 teachers from secondary schools in 17 European countries participated together with representatives of national ministries and local authorities, as well as professional astronomers. This meeting was the first of its kind ever held and was very successful. As a most visible and immediate outcome, the participants agreed to form the "European Association for Astronomy Education (EAAE)", uniting astronomy educators all over Europe into one network. A provisional Executive Committee of the EAAE was elected which will work towards the organisation of a constitutional conference within the next year. The participants unanimously adopted a "Declaration on the Teaching of Astronomy in Europe", specifying the overall aims and initial actions needed to achieve them. Astronomy: Science, Technology and Culture At the beginning of the Workshop the participants listened to lectures by several specialists about some of the most active fields of astronomy. The scientific sessions included topics as diverse as minor bodies in the solar system, nucleosynthesis, interstellar chemistry and cosmology. Then followed overviews of various recent advances in astronomical technology, some of which are already having direct impact on highly specialized sectors of European industry. They included the advanced use of computers in astronomy, for instance within image processing and data archiving, as well as a demonstration of remote observing. Discussing the cultural aspects, Nigel Calder (UK) and Hubert Reeves (France) emphasized the important role of astronomy in modern society, in particular its continuing influence on our perceptions of mankind's unique location in time and space. Teaching of Astronomy in European Countries

Two VLT 8.2-m Unit Telescopes in Action

NASA Astrophysics Data System (ADS)

1999-04-01

Visitors at ANTU - Astronomical Images from KUEYEN The VLT Control Room at the Paranal Observatory is becoming a busy place indeed. From here, two specialist teams of ESO astronomers and engineers now operate two VLT 8.2-m Unit Telescopes in parallel, ANTU and KUEYEN (formerly UT1 and UT2, for more information about the naming and the pronunciation, see ESO Press Release 06/99 ). Regular science observations have just started with the first of these giant telescopes, while impressive astronomical images are being obtained with the second. The work is hard, but the mood in the control room is good. Insiders claim that there have even been occasions on which the groups have had a friendly "competition" about which telescope makes the "best" images! The ANTU-team has worked with the FORS multi-mode instrument , their colleagues at KUEYEN use the VLT Test Camera for the ongoing tests of this new telescope. While the first is a highly developed astronomical instrument with a large-field CCD imager (6.8 x 6.8 arcmin 2 in the normal mode; 3.4 x 3.4 arcmin 2 in the high-resolution mode), the other is a less complex CCD camera with a smaller field (1.5 x 1.5 arcmin 2 ), suited to verify the optical performance of the telescope. As these images demonstrate, the performance of the second VLT Unit Telescope is steadily improving and it may not be too long before its optical quality will approach that of the first. First KUEYEN photos of stars and galaxies We present here some of the first astronomical images, taken with the second telescope, KUEYEN, in late March and early April 1999. They reflect the current status of the optical, electronic and mechanical systems, still in the process of being tuned. As expected, the experience gained from ANTU last year has turned out to be invaluable and has allowed good progress during this extremely delicate process. ESO PR Photo 19a/99 ESO PR Photo 19a/99 [Preview - JPEG: 400 x 433 pix - 160k] [Normal - JPEG: 800 x 866 pix - 457k] [High

Little Brother Joins the Large Family

NASA Astrophysics Data System (ADS)

2006-12-01

On the night of 15 December 2006, the fourth and last-to-be-installed VLTI Auxiliary Telescope (AT4) obtained its 'First Light'. The first images demonstrate that AT4 will be able to deliver the excellent image quality already delivered by the first three ATs. It will soon join its siblings to perform routinely interferometric measurements. ESO PR Photo 51a/06 ESO PR Photo 51a/06 VLT Auxiliary Telescope The VLT is composed of four 8.2-m Unit Telescope (Antu, Kueyen, Melipal and Yepun). They have been progressively put into service together with a vast suite of the most advanced astronomical instruments and are operated every night in the year. Contrary to other large astronomical telescopes, the VLT was designed from the beginning with the use of interferometry as a major goal. The VLT Interferometer (VLTI) combines starlight captured by two or three 8.2- VLT Unit Telescopes, dramatically increasing the spatial resolution and showing fine details of a large variety of celestial objects. ESO PR Photo 51b/06 ESO PR Photo 51b/06 One AT Under the Sky However, most of the time the large telescopes are used for other research purposes. They are therefore only available for interferometric observations during a limited number of nights every year. Thus, in order to exploit the VLTI each night and to achieve the full potential of this unique setup, some other (smaller), dedicated telescopes were included into the overall VLT concept. These telescopes, known as the VLTI Auxiliary Telescopes (ATs), are mounted on tracks and can be placed at precisely defined "parking" observing positions on the observatory platform. From these positions, their light beams are fed into the same common focal point via a complex system of reflecting mirrors mounted in an underground system of tunnels. The Auxiliary Telescopes are real technological jewels. They are placed in ultra-compact enclosures, complete with all necessary electronics, an air conditioning system and cooling liquid for

Participant Perspectives on the ESO Astronomy Camp Programme

NASA Astrophysics Data System (ADS)

Olivotto, C.; Cenadelli, D.; Gamal, M.; Grossmann, D.; Teller, L. A. I.; Marta, A. S.; Matoni, C. L.; Taillard, A.

2015-09-01

This article describes the experience of attending the European Southern Observatory (ESO) Astronomy Camp from the perspective of its participants - students aged between 16 and 18 years old from around the world. The students shared a week together during the winter of 2014 in the Alpine village of Saint-Barthelemy, Italy. The camp was organised by ESO in collaboration with Sterrenlab and the Astronomical Observatory of the Autonomous Region of the Aosta Valley and offered a rich programme of astronomy and leisure activities. This article focuses on the concept of astronomy camps, and their role as a unique tool to complement formal classroom education, rather than on the astronomy activities and the scientific programme. Thus, it is not an academic review of the implemented methodologies, but rather a reflection on the overall experience. The article was brought together from collaborative accounts by some of the participants who were asked to reflect on the experience. The participants who contributed to this article represent the diversity of the ESO Astronomy Camp's alumni community.

The VLT Opening Symposium

NASA Astrophysics Data System (ADS)

1999-02-01

. The text below summarizes the individual projects. Comprehensive texts with all photos and diagrammes are available in nine separate web documents ( ESO PR Photos 08/99 to 16/99 ) that may be accessed via the links at the top of each section. The degree of detail and level of complexity of the texts depend on the subject and the available materials. 1. Dwarf Galaxies in the Local Group ESO PR Photo 10a/99 ESO PR Photo 10a/99 The Antlia Galaxy (FORS1 colour composite) . Access full text and PR Photos 10a-d/99 In addition to large spiral galaxies like the Milky Way Galaxy, the Andromeda Galaxy and Messier 33, the Local Group of Galaxies contains many dwarf galaxies. The VLT has observed two of these, Antlia and NGC 6822 . Antlia is a low-surface brightness, spheroidal dwarf galaxy that was only discovered in 1997. While it contains a large amount of atomic hydrogen at its centre, no young stars are found, and it appears that most of its stars are old. This is unlike other dwarf galaxies in the Milky Way neighbourhood, as star formation is expected to occur within dense hydrogen clouds. Further observations will be necessary to understand this unusual characteristics. The VLT also obtained images of an irregular dwarf galaxy in the Local Group, NGC 6822, as well as spectra of some of its stars. This galaxy is of the "irregular" type and is situated at a distance of about 2 million light-years. A comparison of the spectra of supergiant stars in NGC 6822 shows that many spectral lines are much weaker than in stars of similar type in the Milky Way, but of similar strength as in stars in the Small Magellanic Cloud. This confirms an earlier finding that NGC 6822 has chemical composition (a lower "metallicity") that is different from what is observed in our Galaxy. 2. The Double Stellar Cluster NGC 1850 in the LMC ESO PR Photo 15/99 ESO PR Photo 15/99 NGC 1850 (FORS1 colour composite) . Access full text and PR Photo 15/99 NGC 1850 is a double cluster in the Large Magellanic

MIDAS - ESO's new image processing system

NASA Astrophysics Data System (ADS)

Banse, K.; Crane, P.; Grosbol, P.; Middleburg, F.; Ounnas, C.; Ponz, D.; Waldthausen, H.

1983-03-01

The Munich Image Data Analysis System (MIDAS) is an image processing system whose heart is a pair of VAX 11/780 computers linked together via DECnet. One of these computers, VAX-A, is equipped with 3.5 Mbytes of memory, 1.2 Gbytes of disk storage, and two tape drives with 800/1600 bpi density. The other computer, VAX-B, has 4.0 Mbytes of memory, 688 Mbytes of disk storage, and one tape drive with 1600/6250 bpi density. MIDAS is a command-driven system geared toward the interactive user. The type and number of parameters in a command depends on the unique parameter invoked. MIDAS is a highly modular system that provides building blocks for the undertaking of more sophisticated applications. Presently, 175 commands are available. These include the modification of the color-lookup table interactively, to enhance various image features, and the interactive extraction of subimages.

The President and the Galaxy

NASA Astrophysics Data System (ADS)

2004-12-01

- JPEG: 640 x 427 pix - 240k] ESO PR Photo 35f/04 ESO PR Photo 35f/04 The Presidential Couple with Professor Maria Teresa Ruiz and the ESO Director General [Preview - JPEG: 500 x 400 pix - 224k] [Normal - JPEG: 1000 x 800 pix - 656k] [FullRes - JPEG: 1575 x 1260 pix - 1.0M] ESO PR Photo 35g/04 ESO PR Photo 35g/04 President Lagos with ESO Staff [Preview - JPEG: 500 x 400 pix - 192k] [Normal - JPEG: 1000 x 800 pix - 592k] [FullRes - JPEG: 1575 x 1200 pix - 1.1M] Captions: ESO PR Photo 35e/04 was obtained during President Lagos' meeting with ESO Staff at the Paranal Residencia. On ESO PR Photo 35f/04, President Lagos and Mrs. Luisa Duran de Lagos are seen at a quiet moment during the visit to the VLT Control Room, together with Prof. Maria Teresa Ruiz (far right), Head of the Astronomy Department at the Universidad de Chile, and the ESO Director General. ESO PR Photo 35g/04 shows President Lagos with some ESO staff members in the Paranal Residencia. VLT obtains a splendid photo of a unique galaxy, NGC 1097 ESO PR Photo 35d/04 ESO PR Photo 35d/04 Spiral Galaxy NGC 1097 (Melipal + VIMOS) [Preview - JPEG: 400 x 525 pix - 181k] [Normal - JPEG: 800 x 1049 pix - 757k] [FullRes - JPEG: 2296 x 3012 pix - 7.9M] Captions: ESO PR Photo 35d/04 is an almost-true colour composite based on three images made with the multi-mode VIMOS instrument on the 8.2-m Melipal (Unit Telescope 3) of ESO's Very Large Telescope. They were taken on the night of December 9-10, 2004, in the presence of the President of the Republic of Chile, Ricardo Lagos. Details are available in the Technical Note below. A unique and very beautiful image was obtained with the VIMOS instrument with President Lagos at the control desk. Located at a distance of about 45 million light-years in the southern constellation Fornax (the Furnace), NGC 1097 is a relatively bright, barred spiral galaxy of type SBb, seen face-on. At magnitude 9.5, and thus just 25 times fainter than the faintest object that can be seen with the

Deformable mirrors development program at ESO

NASA Astrophysics Data System (ADS)

Stroebele, Stefan; Vernet, Elise; Brinkmann, Martin; Jakob, Gerd; Lilley, Paul; Casali, Mark; Madec, Pierre-Yves; Kasper, Markus

2016-07-01

Over the last decade, adaptive optics has become essential in different fields of research including medicine and industrial applications. With this new need, the market of deformable mirrors has expanded a lot allowing new technologies and actuation principles to be developed. Several E-ELT instruments have identified the need for post focal deformable mirrors but with the increasing size of the telescopes the requirements on the deformable mirrors become more demanding. A simple scaling up of existing technologies from few hundred actuators to thousands of actuators will not be sufficient to satisfy the future needs of ESO. To bridge the gap between available deformable mirrors and the future needs for the E-ELT, ESO started a development program for deformable mirror technologies. The requirements and the path to get the deformable mirrors for post focal adaptive optics systems for the E-ELT is presented.

ESO and Fokker Space Sign Contract about VLTI Delay Line

NASA Astrophysics Data System (ADS)

1998-03-01

The European Southern Observatory is building the world's largest optical telescope, the Very Large Telescope (VLT) , at the ESO Paranal Observatory in Chile. The VLT consists of four 8.2-m unit telescopes and several smaller, moveable Auxiliary Telescopes. When coupled as the giant VLT Interferometer (VLTI) , they will together provide the sharpest images ever obtained by any optical telescope. It will in principle be able to see an astronaut on the surface of the Moon, 400,000 km away. The VLTI Delay Lines Fokker Space (Leiden, The Netherlands) has been awarded a contract for the delivery of the Delay Line of the VLTI. This is a mechanical-optical system that will compensate the optical path differences of the light beams from the individual telescopes. Such a system is necessary to ensure that the light from all telescopes arrive in the same phase at the focal point of the interferometer. Otherwise, the very sharp interferometric images cannot be obtained. ESO PR Photo 08/98 [JPEG, 102k] Schematic representation of the VLTI Delay Line, showing the retro-reflector on its moving base. For more details, please consult the technical explanation below. This highly accurate system will be developed in close co-operation with the Dutch institute TNO-TPD (Netherlands Organization for Applied Scientific Research - Institute of Applied Physics) . The most innovative feature of the Delay Line is the new control strategy, a two-stage control system, based on linear motor technology, combined with high accuracy piezo-electric control elements. This enables the system to position the so-called cat's eye reflector system with an accuracy of only a few nanometers (millionth of a millimetre (nm)) over a stroke length of 60 metres. Within radio astronomy, interferometric techniques have been applied by Dutch astronomers since many years. They will now be able to contribute with their extensive knowledge of such systems to the next generation of astronomical interferometric

Feeding the Monster

NASA Astrophysics Data System (ADS)

2005-10-01

Near-infrared images of the active galaxy NGC 1097, obtained with the NACO adaptive optics instrument on ESO's Very Large Telescope, disclose with unprecedented detail a complex central network of filamentary structure spiralling down to the centre of the galaxy. These observations provide astronomers with new insights on how super-massive black holes lurking inside galaxies get fed. "This is possibly the first time that a detailed view of the channelling process of matter, from the main part of the galaxy down to the very end in the nucleus is released," says Almudena Prieto (Max-Planck Institute, Heidelberg, Germany), lead author of the paper describing these results. Located at a distance of about 45 million light-years in the southern constellation Fornax (the Furnace), NGC 1097 is a relatively bright, barred spiral galaxy seen face-on. At magnitude 9.5, and thus just 25 times fainter than the faintest object that can be seen with the unaided eye, it appears in small telescopes as a bright, circular disc. NGC 1097 is a very moderate example of an Active Galactic Nucleus (AGN), whose emission is thought to arise from matter (gas and stars) falling into oblivion in a central black hole. However, NGC 1097 possesses a comparatively faint nucleus only, and the black hole in its centre must be on a very strict "diet": only a small amount of gas and stars is apparently being swallowed by the black hole at any given moment. Astronomers have been trying to understand for a long time how the matter is "gulped" down towards the black hole. Watching directly the feeding process requires very high spatial resolution at the centre of galaxies. This can be achieved by means of interferometry as was done with the VLTI MIDI instrument on the central parts of another AGN, NGC 1068 (see ESO PR 17/03), or with adaptive optics [1]. Thus, astronomers [2] obtained images of NGC 1097 with the adaptive optics NACO instrument attached to Yepun, the fourth Unit Telescope of ESO's VLT

AO WFS detector developments at ESO to prepare for the E-ELT

NASA Astrophysics Data System (ADS)

Downing, Mark; Casali, Mark; Finger, Gert; Lewis, Steffan; Marchetti, Enrico; Mehrgan, Leander; Ramsay, Suzanne; Reyes, Javier

2016-07-01

ESO has a very active on-going AO WFS detector development program to not only meet the needs of the current crop of instruments for the VLT, but also has been actively involved in gathering requirements, planning, and developing detectors and controllers/cameras for the instruments in design and being proposed for the E-ELT. This paper provides an overall summary of the AO WFS Detector requirements of the E-ELT instruments currently in design and telescope focal units. This is followed by a description of the many interesting detector, controller, and camera developments underway at ESO to meet these needs; a) the rationale behind and plan to upgrade the 240x240 pixels, 2000fps, "zero noise", L3Vision CCD220 sensor based AONGC camera; b) status of the LGSD/NGSD High QE, 3e- RoN, fast 700fps, 1760x1680 pixels, Visible CMOS Imager and camera development; c) status of and development plans for the Selex SAPHIRA NIR eAPD and controller. Most of the instruments and detector/camera developments are described in more detail in other papers at this conference.

Reaching New Heights in Astronomy - ESO Long Term Perspectives

NASA Astrophysics Data System (ADS)

de Zeeuw, T.

2016-12-01

A comprehensive description of ESO in the current global astronomical context, and its plans for the next decade and beyond, are presented. This survey covers all aspects of the Organisation, including the optical-infrared programme at the La Silla Paranal Observatory, the submillimetre facilities ALMA and APEX, the construction of the 39-metre European Extremely Large Telescope and the science operation of these facilities. An extension of the current optical/infrared/submillimetre facilities into multi-messenger astronomy has been made with the decision to host the southern Cherenkov Telescope Array at Paranal. The structure of the Organisation is presented and the further development of the staff is described within the scope of the long-range financial planning. The role of Chile is highlighted and expansion of the number of Member States beyond the current 15 is discussed. The strengths of the ESO model, together with challenges as well as possible new opportunities and initiatives, are examined and a strategy for the future of ESO is outlined.

VIMOS - a Cosmology Machine for the VLT

NASA Astrophysics Data System (ADS)

2002-03-01

" was achieved on February 26, 2002, and a first series of test observations has successfully demonstrated the huge potential of this amazing facility. Much work on VIMOS is still ahead during the coming months in order to put into full operation and fine-tune the most efficient "galaxy cruncher" in the world. VIMOS is the outcome of a fruitful collaboration between ESO and several research institutes in France and Italy, under the responsibility of the Laboratoire d'Astrophysique de Marseille (CNRS, France). The other partners in the "VIRMOS Consortium" are the Laboratoire d'Astrophysique de Toulouse, Observatoire Midi-Pyrénées, and Observatoire de Haute-Provence in France, and Istituto di Radioastronomia (Bologna), Istituto di Fisica Cosmica e Tecnologie Relative (Milano), Osservatorio Astronomico di Bologna, Osservatorio Astronomico di Brera (Milano) and Osservatorio Astronomico di Capodimonte (Naples) in Italy. PR Photo 09a/02 : VIMOS image of the Antennae Galaxies (centre). PR Photo 09b/02 : First VIMOS Multi-Object Spectrum (full field) PR Photo 09c/02 : The VIMOS instrument on VLT MELIPAL PR Photo 09d/02 : The VIMOS team at "First Light". PR Photo 09e/02 : "First Light" image of NGC 5364 PR Photo 09f/02 : Image of the Crab Nebula PR Photo 09g/02 : Image of spiral galaxy NGC 2613 PR Photo 09h/02 : Image of spiral galaxy Messier 100 PR Photo 09i/02 : Image of cluster of galaxies ACO 3341 PR Photo 09j/02 : Image of cluster of galaxies MS 1008.1-1224 PR Photo 09k/02 : Mask design for MOS exposure PR Photo 09l/02 : First VIMOS Multi-Object Spectrum (detail) PR Photo 09m/02 : Integrated Field Spectroscopy of central area of the "Antennae Galaxies" PR Photo 09n/02 : Integrated Field Spectroscopy of central area of the "Antennae Galaxies" (detail) Science with VIMOS ESO PR Photo 09a/02 ESO PR Photo 09a/02 [Preview - JPEG: 400 x 469 pix - 152k] [Normal - JPEG: 800 x 938 pix - 408k] ESO PR Photo 09b/02 ESO PR Photo 09b/02 [Preview - JPEG: 400 x 511 pix - 304k] [Normal

The big comet crash of 1994. Intensive observational campaign at ESO

NASA Astrophysics Data System (ADS)

1994-01-01

-based radio telescopes, as well as from several spacecraft, including Ulysses, now en route towards its first pass below the Sun. There may also be changes in the plasma torus that girdles Jupiter near the orbit of the volcanic moon Io, and some cometary dust particles may collect in Jupiter's faint ring. All in all, this spectacular event offers a unique opportunity to study Jupiter and its atmosphere. It may also provide a first ``look'' into its hitherto unobservable inner regions. Nobody knows for sure, how dramatic the effects of the impacts will actually be, but unless we are prepared to observe them, we may lose a great chance that is unlikely to come back in many years, if ever. WHICH PREPARATIONS HAVE BEEN MADE AT ESO ? In November of last year, a group of 25 cometary and planetary specialists from Europe and the U.S.A. met at ESO to discuss possible observations from the ESO La Silla observatory in connection with the cometary impacts at Jupiter. In a resulting report, they emphazised that ESO is in a particularly advantageous situation in this respect, because the excellent site of this observatory is located in the south and Jupiter will be 12 degrees south of the celestial equator at the time of the event and therefore well observable from here; the time available from observatories in the northern hemisphere will be much more restricted. Moreover, many different observing techniques are available at La Silla; this provides optimal conditions for effective coordination of the various programmes, in particular what concerns imaging and spectral observations in the infrared and submillimetre wavebands. A joint request for a coordinated observing programme was submitted by the group to the ESO Observing Programmes Committee. During its meeting at the end of November 1993, this committee reacted very positively and a substantial number of observing nights at the major telescopes at La Silla was granted at the time of the impacts in July 1994. The total amount of

If we build it, will they come? Curation and use of the ESO telescope bibliography

NASA Astrophysics Data System (ADS)

Grothkopf, Uta; Meakins, Silvia; Bordelon, Dominic

2015-12-01

The ESO Telescope Bibliography (telbib) is a database of refereed papers published by the ESO users community. It links data in the ESO Science Archive with the published literature, and vice versa. Developed and maintained by the ESO library, telbib also provides insights into the organization's research output and impact as measured through bibliometric studies. Curating telbib is a multi-step process that involves extensive tagging of the database records. Based on selected use cases, this talk will explain how the rich metadata provide parameters for reports and statistics in order to investigate the performance of ESO's facilities and to understand trends and developments in the publishing behaviour of the user community.

Development of [⁶⁴Cu]-DOTA-PR81 radioimmunoconjugate for MUC-1 positive PET imaging.

PubMed

Alirezapour, Behrouz; Rasaee, Mohammad Javad; Jalilian, Amir Reza; Rajabifar, Saeed; Mohammadnejad, Javad; Paknejad, Malihe; Maadi, Ehsan; Moradkhani, Sedigheh

2016-01-01

Breast cancer radioimmunoscintigraphy targeting MUC1 expression is a growing field of work in nuclear medicine research. PR81 is a monoclonal antibody that binds with high affinity to MUC1, which is over expressed on breast tumors. In this study, we report production, quality control and preclinical qualifications of a copper-64 labeled PR81 for PET imaging of breast cancer. PR81 was conjugated with DOTA-NHS-ester and purified by molecular filtration followed by chelate:mAb ratio determination by spectrophotometric method. DOTA-PR81 was labeled with (64)Cu followed by radiochemical purity, in vitro stability, in vitro internalization and immunoreactivity determination. The tissue biodistribution of the (64)Cu-DOTA-PR81 and (64)Cu-DOTA-hIgG was evaluated in BALB/c mice with breast carcinoma tumors using tissue counting and imaging. The radiochemical purity of radioimmunoconjugate was >95±1.9% (ITLC) (specific activity; 4.6 μCi/μg). The average number of chelators per antibody was 3.4±0.3:1. The (64)Cu-DOTA-PR81 showed immunoreactivity towards MUC1 antigen and MCF7 cell line with significant in vitro stability (>89% in PBS and 78±0.5% in human serum) over 48 h. Maximum internalized activity of radiolabeled PR81 in 4-8 h was 81.5%. The biodistribution and scintigraphy studies showed the accumulation of the complex at the site of tumors with high sensitivity and specificity compared to control probes. The results showed that (64)Cu-DOTA-PR81 may be considered as a potential PET tracer for diagnosis and follow-up of MUC1 expression in oncology. Copyright © 2015 Elsevier Inc. All rights reserved.

First Giant Mirror for the ESO VLT Ready at REOSC

NASA Astrophysics Data System (ADS)

1995-11-01

The REOSC Contract In 1989, the European Southern Observatory (ESO), the European Organisation for Astronomy, awarded to REOSC, a subsidiary of the SFIM Group and located in Saint Pierre du Perray (France), a comprehensive contract for the polishing of four 8.2-metre diameter mirrors for the unit telescopes of the ESO Very Large Telescope (VLT) project. These mirrors are the largest ever manufactured and polished. This contract comprises not only the polishing and high-precision optical testing of each giant mirror, but also the safe condition of transportation of the blanks which were manufactured by Schott Glaswerke in Mainz (Germany). In order to fulfill the contract, REOSC conceived, built and equipped a novel, high-tech workshop which would allow to polish and test the mirrors, each of which has a surface area of more than 50 square metres. First 8.2-Metre Mirror is Ready and within Specifications The REOSC polishing facility for giant mirrors was built in Saint Pierre du Perray, just south of Paris. It is equipped with two machines: one for grinding and the other for polishing the mirrors, and both with 150-actuator systems that support the thin and flexible mirrors. All equipment is computer controlled. State-of-the-art interferometers probe the accuracy of the mirror surface as the polishing proceeds; they are installed at the top level of the facility in a 30-metre high tower, at the centre of the mirror's radius of curvature. The success of the work at REOSC is now evident by the fact that careful measurements of the first mirror earlier this month have shown that the final optical surface is correct to within 0.00005 millimetres. For illustration, this corresponds to an accuracy of only 1 millimetre deviation over a surface with a diameter of 165 kilometres (equivalent to the entire Paris area)! ESO Receives the First VLT Mirror After having been carefully placed in a special transport box designed by REOSC, the first mirror blank, weighing 23.5 tons and

PESSTO: The Public ESO Spectroscopic Survey of Transient Objects

NASA Astrophysics Data System (ADS)

Smartt, S. J.; Valenti, S.; Fraser, M.; Inserra, C.; Young, D. R.; Sullivan, M.; Benetti, S.; Gal-Yam, A.; Knapic, C.; Molinaro, M.; Pastorello, A.; Smareglia, R.; Smith, K. W.; Taubenberger, S.; Yaron, O.

2013-12-01

PESSTO, which began in April 2012 as one of two ESO public spectroscopic surveys, uses the EFOSC2 and SOFI instruments on the New Technology Telescope during ten nights a month for nine months of the year. Transients for PESSTO follow-up are provided by dedicated large-field 1-2-metre telescope imaging surveys. In its first year PESSTO classified 263 optical transients, publicly released the reduced spectra within 12 hours of the end of the night and identified 33 supernovae (SNe) for dedicated follow-up campaigns. Nine papers have been published or submitted on the topics of supernova progenitors, the origins of type ia SNe, the uncertain nature of faint optical transients and superluminous supernovae, and a definitive public dataset on a most intriguing supernova, the infamous SN2009ip.

Feeling the Heat

NASA Astrophysics Data System (ADS)

2004-05-01

Successful "First Light" for the Mid-Infrared VISIR Instrument on the VLT Summary Close to midnight on April 30, 2004, intriguing thermal infrared images of dust and gas heated by invisible stars in a distant region of our Milky Way appeared on a computer screen in the control room of the ESO Very Large Telescope (VLT). These images mark the successful "First Light" of the VLT Imager and Spectrometer in the InfraRed (VISIR), the latest instrument to be installed on this powerful telescope facility at the ESO Paranal Observatory in Chile. The event was greeted with a mixture of delight, satisfaction and some relief by the team of astronomers and engineers from the consortium of French and Dutch Institutes and ESO who have worked on the development of VISIR for around 10 years [1]. Pierre-Olivier Lagage (CEA, France), the Principal Investigator, is content : "This is a wonderful day! A result of many years of dedication by a team of engineers and technicians, who can today be proud of their work. With VISIR, astronomers will have at their disposal a great instrument on a marvellous telescope. And the gain is enormous; 20 minutes of observing with VISIR is equivalent to a whole night of observing on a 3-4m class telescope." Dutch astronomer and co-PI Jan-Willem Pel (Groningen, The Netherlands) adds: "What's more, VISIR features a unique observing mode in the mid-infrared: spectroscopy at a very high spectral resolution. This will open up new possibilities such as the study of warm molecular hydrogen most likely to be an important component of our galaxy." PR Photo 16a/04: VISIR under the Cassegrain focus of the Melipal telescope PR Photo 16b/04: VISIR mounted behind the mirror of the Melipal telescope PR Photo 16c/04: Colour composite of the star forming region G333.6-0.2 PR Photo 16d/04: Colour composite of the Galactic Centre PR Photo 16e/04: The Ant Planetary Nebula at 12.8 μm PR Photo 16f/04: The starburst galaxy He2-10 at 11.3μm PR Photo 16g/04: High

VizieR Online Data Catalog: KiDS-ESO-DR2 multi-band source catalog (de Jong+, 2015)

NASA Astrophysics Data System (ADS)

de Jong, J. T. A.; Verdoes Kleijn, G. A.; Boxhoorn, D. R.; Buddelmeijer, H.; Capaccioli, M.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; Kuijken, K.; La Barbera, F.; McFarland, J. P.; Napolitano, N. R.; Radovich, M.; Sikkema, G.; Valentijn, E. A.; Begeman, K. G.; Brescia, M.; Cavuoti, S.; Choi, A.; Cordes, O.-M.; Covone, G.; Dall'Ora, M.; Hildebrandt, H.; Longo, G.; Nakajima, R.; Paolillo, M.; Puddu, E.; Rifatto, A.; Tortora, C.; van Uitert, E.; Buddendiek, A.; Harnois-Deraps, J.; Erben, T.; Eriksen, M. B.; Heymans, C.; Hoekstra, H.; Joachimi, B.; Kitching, T. D.; Klaes, D.; Koopmans, L. V. E.; Koehlinger, F.; Roy, N.; Sifon, C.; Schneider, P.; Sutherland, W. J.; Viola, M.; Vriend, W.-J.

2016-10-01

KiDS data releases consist of ~1 square degree tiles that have been successfully observed in all four survey filters (u,g,r,i). The second data release (KiDS-ESO-DR2) was available in February 2015 and contains imaging data, masks and single-band source lists for all tiles observed in all four filters for which observations were completed during the second year of regular operations (1 October 2012 to 31 September 2013), a total of 98 tiles. Apart from the data products mentioned above, KiDS-ESO-DR2 also provides a multi-band source catalogue based on the combined set of 148 tiles released in the first two data releases. A complete list of all tiles with data quality parameters can be found on the KiDS website: http://kids.strw.leidenuniv.nl/DR2/ (1 data file).

New Method for Data Treatment Developed at ESO

NASA Astrophysics Data System (ADS)

1996-08-01

How Future Astronomical Observations Will be Done The past four centuries have seen dramatic improvements in astronomical equipment, in terms of better and larger telescopes, more accurate and sensitive detectors and, not the least, by advanced space instruments with access to new spectral regions. However, until recently there has been little progress on another equally important front, that of quantifying the unavoidable influence of this equipment on the astronomical data they produce . For a long time, astronomers have desired to remove efficiently these `instrumental effects' from their data, in order to give them a clearer understanding of the objects in the Universe and their properties. But it is only now that this fundamental problem can finally be tackled efficiently, with the advent of digital imaging techniques and powerful computers. Two researchers at the ESO Headquarters, Michael R. Rosa of the Space Telescope European Co-ordinating Facility (ST/ECF [1]) and Pascal Ballester of the Data Management Division (DMD) are now developing a new approach to this age-old problem. These results are important for the future use of the ESO Very Large Telescope (VLT) , the Hubble Space Telescope (HST) and other large facilities as well [2]. The observational process Observations are crucial to the progress of all natural sciences, including astronomy. Nevertheless, the properties of the observed objects are rarely revealed directly. First, observational data are gathered at the telescopes with instruments such as cameras and spectrophotometers. Then these `raw' data are processed with advanced computer programmes to produce scientifically meaningful data which are finally scrutinized by the astronomers in order to learn more about the observed celestial objects. A basic problem in this chain is the influence of the telescopes and instruments on the data they produce. The `raw' observational data carries the marks, not only of the celestial objects that are

The Great Easter Egg Hunt: The Void's Incredible Richness

NASA Astrophysics Data System (ADS)

2006-04-01

An image made of about 300 million pixels is being released by ESO, based on more than 64 hours of observations with the Wide-Field Camera on the 2.2m telescope at La Silla (Chile). The image covers an 'empty' region of the sky five times the size of the full moon, opening an exceptionally clear view towards the most distant part of our universe. It reveals objects that are 100 million times fainter than what the unaided eye can see. Easter is in many countries a time of great excitement for children who are on the big hunt for chocolate eggs, hidden all about the places. Astronomers, however, do not need to wait this special day to get such an excitement: it is indeed daily that they look for faraway objects concealed in deep images of the sky. And as with chocolate eggs, deep sky objects, such as galaxies, quasars or gravitational lenses, come in the wildest variety of colours and shapes. ESO PR Photo 11/06 ESO PR Photo 14a/06 The Deep 3 'Empty' Field The image presented here is one of such very deep image of the sky. It is the combination of 714 frames for a total exposure time of 64.5 hours obtained through four different filters (B, V, R, and I)! It consists of four adjacent Wide-Field Camera pointings (each 33x34 arcmin), covering a total area larger than one square degree. Yet, if you were to look at this large portion of the firmament with the unaided eye, you would just see... nothing. The area, named Deep 3, was indeed chosen to be a random but empty, high galactic latitude field, positioned in such a way that it can be observed from the La Silla observatory all over the year. Together with two other regions, Deep 1 and Deep 2, Deep 3 is part of the Deep Public Survey (DPS), based on ideas submitted by the ESO community and covering a total sky area of 3 square degrees. Deep 1 and Deep 2 were selected because they overlapped with regions of other scientific interest. For instance, Deep 1 was chosen to complement the deep ATESP radio survey carried out

ESO Signs Largest-Ever European Industrial Contract For Ground-Based Astronomy Project ALMA

NASA Astrophysics Data System (ADS)

2005-12-01

coordinating consortiums in charge of complex, high-performance ground systems." ALMA is an international astronomy facility. It is a partnership between Europe, North America and Japan, in cooperation with the Republic of Chile. The European contribution is funded by ESO and Spain, with the construction and operations being managed by ESO. A matching contribution is being made by the USA and Canada, who will also provide 25 antennas. Japan will provide additional antennas, thus making this a truly worldwide endeavour. ALMA will be located on the 5,000m high Llano de Chajnantor site in the Atacama Desert of Northern Chile. ALMA will consist of a giant array of 12-m antennas separated by baselines of up to 18 km and is expected to start partial operation by 2010-2011. The excellent site, the most sensitive receivers developed so far, and the large number of antennas will allow ALMA to have a sensitivity that is many times better than any other comparable instrument. "ALMA will bring to sub-millimetre astronomy the aperture synthesis techniques of radio astronomy, enabling precision imaging to be done on sub-arcsecond angular scales, and will nicely complement the ESO VLT/VLTI observatory", said Dr. Hans Rykaczewski, the ALMA European Project Manager. Millimetre-wave astronomy is the study of the universe in the spectral region between what is traditionally considered radio waves and infrared radiation. In this realm, ALMA will study the evolution of galaxies, including very early stages, gather crucial data on the formation of stars, proto-planetary discs, and planets, and provide new insights on the familiar objects of our own solar system. A prototype antenna had already been built by Alcatel Alenia Space and European Industrial Engineering and thoroughly tested along with prototypes antennas from Vertex/LSI and Mitsubishi at the ALMA Antenna Test Facility located at the Very Large Array site in Socorro, New Mexico. For more information on the ALMA project, please go to http://www.eso.org/projects/alma/.

The AMBRE Project: Stellar parameterisation of the ESO:UVES archived spectra

NASA Astrophysics Data System (ADS)

Worley, C. C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Bijaoui, A.

2016-06-01

Context. The AMBRE Project is a collaboration between the European Southern Observatory (ESO) and the Observatoire de la Côte d'Azur (OCA) that has been established to determine the stellar atmospheric parameters for the archived spectra of four ESO spectrographs. Aims: The analysis of the UVES archived spectra for their stellar parameters was completed in the third phase of the AMBRE Project. From the complete ESO:UVES archive dataset that was received covering the period 2000 to 2010, 51 921 spectra for the six standard setups were analysed. These correspond to approximately 8014 distinct targets (that comprise stellar and non-stellar objects) by radial coordinate search. Methods: The AMBRE analysis pipeline integrates spectral normalisation, cleaning and radial velocity correction procedures in order that the UVES spectra can then be analysed automatically with the stellar parameterisation algorithm MATISSE to obtain the stellar atmospheric parameters. The synthetic grid against which the MATISSE analysis is carried out is currently constrained to parameters of FGKM stars only. Results: Stellar atmospheric parameters are reported for 12 403 of the 51 921 UVES archived spectra analysed in AMBRE:UVES. This equates to ~23.9% of the sample and ~3708 stars. Effective temperature, surface gravity, metallicity, and alpha element to iron ratio abundances are provided for 10 212 spectra (~19.7%), while effective temperature at least is provided for the remaining 2191 spectra. Radial velocities are reported for 36 881 (~71.0%) of the analysed archive spectra. While parameters were determined for 32 306 (62.2%) spectra these parameters were not considered reliable (and thus not reported to ESO) for reasons such as very low S/N, too poor radial velocity determination, spectral features too broad for analysis, and technical issues from the reduction. Similarly the parameters of a further 7212 spectra (13.9%) were also not reported to ESO based on quality criteria and error

The Challenges in Metadata Management: 20+ Years of ESO Data

NASA Astrophysics Data System (ADS)

Vera, I.; Da Rocha, C.; Dobrzycki, A.; Micol, A.; Vuong, M.

2015-09-01

The European Southern Observatory Science Archive Facility has been in operations for more than 20 years. It contains data produced by ESO telescopes as well as the metadata needed for characterizing and distributing those data. This metadata is used to build the different archive services provided by the Archive. Over these years, services have been added, modified or even decommissioned creating a cocktail of new, evolved and legacy data systems. The challenge for the Archive is to harmonize the differences of those data systems to provide the community with a homogeneous experience when using ESO data. In this paper, we present ESO experience in three particular challenging areas. First discussion is dedicated to the problem of metadata quality over the time, second discusses how to integrate obsolete data models on the current services and finally we will present the challenges of ever growing databases. We describe our experience dealing with those issues and the solutions adopted to mitigate them.

Island Universes with a Twist

NASA Astrophysics Data System (ADS)

2006-07-01

If life is like a box of chocolates - you never know what you will get - the Universe, with its immensely large variety of galaxies, must be a real candy store! ESO's Very Large Telescope has taken images of three different 'Island Universes' [1], each amazing in their own way, whose curious shapes testify of a troubled past, and for one, of a foreseeable doomed future. ESO PR Photo 27a/06 ESO PR Photo 27a/06 The Starburst Galaxy NGC 908 The first galaxy pictured is NGC 908, located 65 million light-years towards the constellation of Cetus (the Whale). This spiral galaxy, discovered in 1786 by William Herschel, is a so-called starburst galaxy, that is, a galaxy undergoing a phase where it spawns stars at a frantic rate. Clusters of young and massive stars can be seen in the spiral arms. Two supernovae, the explosions of massive stars, have been recorded in the near past: one in 1994 and another in May of this year. The galaxy, which is about 75 000 light-years long, also clearly presents uneven and thick spiral arms, the one on the left appearing to go upwards, forming a kind of ribbon. These properties indicate that NGC 908 most probably suffered a close encounter with another galaxy, even though none is visible at present. ESO PR Photo 27b/06 ESO PR Photo 27b/06 The Spectacular Spiral Galaxy ESO 269-G57 The second galaxy featured constitutes another wonderful sight yet of a more timid nature: it does not belong to the NGC catalogue [2], like so many of its more famous brethren. Its less well-known designation, ESO 269-G57, refers to the ESO/Uppsala Survey of the Southern Sky in the 1970's during which over 15,000 southern galaxies were found with the ESO Schmidt telescope and catalogued. Located about 155 million light-years away towards the southern constellation Centaurus (the Centaur), ESO 269-G57 is a spectacular spiral galaxy of symmetrical shape that belongs to a well-known cluster of galaxies seen in this direction. An inner 'ring', of several tightly

NASA and ESA astronauts visit ESO. Hubble repair team meets European astronomers in Garching.

NASA Astrophysics Data System (ADS)

1994-02-01

On Wednesday, February 16, 1994, seven NASA and ESA astronauts and their spouses will spend a day at the Headquarters of the European Southern Observatory. They are the members of the STS-61 crew that successfully repaired the Hubble Space Telescope during a Space Shuttle mission in December 1993. This will be the only stop in Germany during their current tour of various European countries. ESO houses the Space Telescope European Coordinating Facility (ST/ECF), a joint venture by the European Space Agency and ESO. This group of astronomers and computer specialists provide all services needed by European astronomers for observations with the Space Telescope. Currently, the European share is about 20 of the total time available at this telescope. During this visit, a Press Conference will be held on Wednesday, February 16, 11:45 - 12:30 at the ESO Headquarters Karl-Schwarzschild-Strasse 2 D-85748 Garching bei Munchen. Please note that participation in this Press Conference is by invitation only. Media representatives may obtain invitations from Mrs. E. Volk, ESO Information Service at this address (Tel.: +49-89-32006276; Fax.: +49-89-3202362), until Friday, February 11, 1994. After the Press Conference, between 12:30 - 14:00, a light refreshment will be served at the ESO Headquarters to all participants. >From 14:00 - 15:30, the astronauts will meet with students and teachers from the many scientific institutes in Garching in the course of an open presentation at the large lecture hall of the Physics Department of the Technical University. It is a 10 minute walk from ESO to the hall. Later the same day, the astronauts will be back at ESO for a private discussion of various space astronomy issues with their astronomer colleagues, many of whom are users of the Hubble Space Telescope, as well as ground-based telescopes at the ESO La Silla Observatory and elsewhere. The astronauts continue to Switzerland in the evening.

Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele

PubMed Central

Gnjatic, Sacha; Nagata, Yasuhiro; Jäger, Elke; Stockert, Elisabeth; Shankara, Srinivas; Roberts, Bruce L.; Mazzara, Gail P.; Lee, Sang Yull; Dunbar, P. Rod; Dupont, Bo; Cerundolo, Vincenzo; Ritter, Gerd; Chen, Yao-Tseng; Knuth, Alexander; Old, Lloyd J.

2000-01-01

NY-ESO-1 elicits frequent antibody responses in cancer patients, accompanied by strong CD8+ T cell responses against HLA-A2-restricted epitopes. To broaden the range of cancer patients who can be assessed for immunity to NY-ESO-1, a general method was devised to detect T cell reactivity independent of prior characterization of epitopes. A recombinant adenoviral vector encoding the full cDNA sequence of NY-ESO-1 was used to transduce CD8-depleted peripheral blood lymphocytes as antigen-presenting cells. These modified antigen-presenting cells were then used to restimulate memory effector cells against NY-ESO-1 from the peripheral blood of cancer patients. Specific CD8+ T cells thus sensitized were assayed on autologous B cell targets infected with a recombinant vaccinia virus encoding NY-ESO-1. Strong polyclonal responses were observed against NY-ESO-1 in antibody-positive patients, regardless of their HLA profile. Because the vectors do not cross-react immunologically, only responses to NY-ESO-1 were detected. The approach described here allows monitoring of CD8+ T cell responses to NY-ESO-1 in the context of various HLA alleles and has led to the definition of NY-ESO-1 peptides presented by HLA-Cw3 and HLA-Cw6 molecules. PMID:11005863

Nuclei of dwarf spheroidal galaxies KKs 3 and ESO 269-66 and their counterparts in our Galaxy

NASA Astrophysics Data System (ADS)

Sharina, M. E.; Shimansky, V. V.; Kniazev, A. Y.

2017-10-01

We present the analysis of medium-resolution spectra obtained at the Southern African Large Telescope for nuclear globular clusters (GCs) in two dwarf spheroidal galaxies (dSphs). The galaxies have similar star formation histories, but they are situated in completely different environments. ESO 269-66 is a close neighbour of the giant S0 NGC 5128. KKs 3 is one of the few truly isolated dSphs within 10 Mpc. We estimate the helium abundance Y = 0.3, age = 12.6 ± 1 Gyr, [Fe/H] = -1.5, -1.55 ± 0.2 dex, and abundances of C, N, Mg, Ca, Ti, and Cr for the nuclei of ESO 269-66 and KKs 3. Our surface photometry results using Hubble Space Telescope images yield the half-light radius of the cluster in KKs 3, rh = 4.8 ± 0.2 pc. We demonstrate the similarities of medium-resolution spectra, ages, chemical compositions, and structure for GCs in ESO 269-66 and KKs 3 and for several massive Galactic GCs with [Fe/H] ∼ -1.6 dex. All Galactic GCs posses Extended Blue Horizontal Branches and multiple stellar populations. Five of the selected Galactic objects are iron-complex GCs. Our results indicate that the sample GCs observed now in different environments had similar conditions of their formation ∼1 Gyr after the Big Bang.

IOT Overview: Wide-Field Imaging

NASA Astrophysics Data System (ADS)

Selman, F. J.

The Wide Field Imager (WFI) instrument at La Silla has been the workhorse of wide-field imaging instruments at ESO for several years. In this contribution I will summarize the issues relating to its productivity for the community both in terms of the quality and quantity of data that has come out of it. Although only surveys of limited scope have been completed using WFI, it is ESO's stepping-stone to the new generation of survey telescopes.

ESO 243-49 HLX-1: scaling of X-ray spectral properties and black hole mass determination

NASA Astrophysics Data System (ADS)

Titarchuk, Lev; Seifina, Elena

2016-11-01

We report the results of Swift/XRT observations (2008-2015) of a hyper-luminous X-ray source, ESO 243-49 HLX-1. We demonstrate a strong observational evidence that ESO 243-49 HLX-1 undergoes spectral transitions from the low/hard state to the high/soft state during these observations. The spectra of ESO 243-49 HLX-1 are well fitted by the so-called bulk motion Comptonization model for all spectral states. We have established the photon index (Γ) saturation level, Γsat = 3.0 ± 0.1, in the Γ versus mass accretion rate (Ṁ) correlation. This Γ-Ṁ correlation allows us to estimate black hole (BH) mass in ESO 243-49 HLX-1 to be MBH 7 × 104 M⊙ assuming the distance to ESO 243-49 of 95 Mpc. For the BH mass estimate we use the scaling method taking Galactic BHs XTE J1550-564, H 1743-322 and 4U 1630-472, and an extragalactic BH source, M101 ULX-1 as reference sources. The Γ versus Ṁ correlation revealed in ESO 243-49 HLX-1 is similar to those in a number of Galactic and extragalactic BHs and it clearly shows the correlation along with the strong Γ saturation at ≈3. This is a robust observational evidence for the presence of a BH in ESO 243-49 HLX-1. We also find that the seed (disk) photon temperatures are quite low, of order of 50-140 eV which are consistent with high BH mass in ESO 243-49 HLX-1.

ESO Public Surveys at VISTA: Lessons learned from Cycle 1 Surveys and the start of Cycle 2

NASA Astrophysics Data System (ADS)

Arnaboldi, M.; Delmotte, N.; Gadotti, D.; Hilker, M.; Hussain, G.; Mascetti, L.; Micol, A.; Petr-Gotzens, M.; Rejkuba, M.; Retzlaff, J.; Ivison, R.; Leibundgut, B.; Romaniello, M.

2017-06-01

The ESO Public Surveys on VISTA serve the science goals of the survey teams while increasing the legacy value of ESO programmes, thanks to their homogeneity and the breadth of their sky coverage in multiple bands. These projects address a variety of research areas: from the detection of planets via microlensing, to stars, the Milky Way and Local Group galaxies, to extragalactic astronomy, galaxy evolution, the high-redshift Universe and cosmology. In 2015, as the first generation of imaging surveys was nearing completion, a second call for Public Surveys was opened to define a coherent scientific programme for VISTA until the commissioning of the wide-field multi-fibre spectrograph, 4MOST, in 2020. This article presents the status of the Cycle 1 surveys as well as an overview of the seven new programmes in Cycle 2, including their science goals, coverage on the sky and observing strategies. We conclude with a forward look at the Cycle 2 data releases and the timelines for their release.

Directed evolution for improved secretion of cancer-testis antigen NY-ESO-1 from yeast.

PubMed

Piatesi, Andrea; Howland, Shanshan W; Rakestraw, James A; Renner, Christoph; Robson, Neil; Cebon, Jonathan; Maraskovsky, Eugene; Ritter, Gerd; Old, Lloyd; Wittrup, K Dane

2006-08-01

NY-ESO-1 is a highly immunogenic tumor antigen and a promising vaccine candidate in cancer immunotherapy. Access to purified protein both for vaccine formulations and for monitoring antigen-specific immune responses is vital to vaccine development. Currently available recombinant Escherichia coli-derived NY-ESO-1 is isolated from inclusion bodies as a complex protein mixture and efforts to improve the purity of this antigen are required, especially for later-stage clinical trials. Using yeast cell surface display and fluorescence activated cell sorting techniques, we have engineered an NY-ESO-1 variant (NY-ESO-L5; C(75)A C(76)A C(78)A L(153)H) with a 100x improved display level on yeast compared to the wild-type protein. This mutant can be effectively produced as an Aga2p-fusion and purified in soluble form directly from the yeast cell wall. In the process, we have identified the epitope recognized by anti-NY-ESO-1 mAb E978 (79-87, GARGPESRL). The availability of an alternative expression host for this important antigen will help avoid artifactual false positive tests of patient immune response due to reaction against expression-host-specific contaminants.

SINFONI Opens with Upbeat Chords

NASA Astrophysics Data System (ADS)

2004-08-01

Dutch Institutes and ESO who have worked on the development of SINFONI for nearly 7 years. The work on SINFONI at Paranal included successful commissioning in June 2004 of the Adaptive Optics Module built by ESO, during which exceptional test images were obtained of the main-belt asteroid (22) Kalliope and its moon. Moreover, the ability was demonstrated to correct the atmospheric turbulence by means of even very faint "guide" objects (magnitude 17.5), crucial for the observation of astronomical objects in many parts of the sky. SPIFFI - SPectrometer for Infrared Faint Field Imaging - was developed at the Max Planck Institute for Extraterrestrische Physik (MPE) in Garching (Germany), in a collaboration with the Nederlandse Onderzoekschool Voor Astronomie (NOVA) in Leiden and the Netherlands Foundation for Research in Astronomy (ASTRON), and ESO. PR Photo 24a/04: SINFONI Adaptive Optics Module at VLT Yepun (June 2004) PR Photo 24b/04: SINFONI at VLT Yepun, now fully assembled (July 2004) PR Photo 24c/04: "First Light" image from the SINFONI Adaptive Optics Module PR Photo 24d/04: AO-corrected Image of a 17.5-magnitude Star PR Photo 24e/04: SINFONI undergoing Balancing and Flexure Tests at VLT Yepun PR Photo 24f/04: SINFONI "First Light" Spectrum of HD 130163 PR Photo 24g/04: Members of the SINFONI Adaptive Optics Module Commissioning Team PR Photo 24h/04: Members of the SPIFFI Commissioning Team PR Photo 24i/04: The Principle of Integral Field Spectroscopy (IFS) PR Photo 24j/04: The Orbital Motion of Linus around (22) Kalliope PR Photo 24k/04: SINFONI Observations of the Galactic Centre Region PR Photo 24l/04: SINFONI Observations of the Circinus Galaxy PR Photo 24m/04: SINFONI Observations of the AGN Galaxy NGC 7469 PR Photo 24n/04: SINFONI Observations of NGC 6240 PR Photo 24o/04: SINFONI Observations of the Young Starforming Galaxies BX 404/405 PR Video Clip 07/04: The Orbital Motion of Linus around (22) Kalliope SINFONI: A powerful and complex instrument ESO PR Photo

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

PubMed Central

Reddy, Hemanth K.N.; Yoon, Chun Hong; Aquila, Andrew; Awel, Salah; Ayyer, Kartik; Barty, Anton; Berntsen, Peter; Bielecki, Johan; Bobkov, Sergey; Bucher, Maximilian; Carini, Gabriella A.; Carron, Sebastian; Chapman, Henry; Daurer, Benedikt; DeMirci, Hasan; Ekeberg, Tomas; Fromme, Petra; Hajdu, Janos; Hanke, Max Felix; Hart, Philip; Hogue, Brenda G.; Hosseinizadeh, Ahmad; Kim, Yoonhee; Kirian, Richard A.; Kurta, Ruslan P.; Larsson, Daniel S.D.; Duane Loh, N.; Maia, Filipe R.N.C.; Mancuso, Adrian P.; Mühlig, Kerstin; Munke, Anna; Nam, Daewoong; Nettelblad, Carl; Ourmazd, Abbas; Rose, Max; Schwander, Peter; Seibert, Marvin; Sellberg, Jonas A.; Song, Changyong; Spence, John C.H.; Svenda, Martin; Van der Schot, Gijs; Vartanyants, Ivan A.; Williams, Garth J.; Xavier, P. Lourdu

2017-01-01

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65–70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. The data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency. PMID:28654088

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source.

PubMed

Reddy, Hemanth K N; Yoon, Chun Hong; Aquila, Andrew; Awel, Salah; Ayyer, Kartik; Barty, Anton; Berntsen, Peter; Bielecki, Johan; Bobkov, Sergey; Bucher, Maximilian; Carini, Gabriella A; Carron, Sebastian; Chapman, Henry; Daurer, Benedikt; DeMirci, Hasan; Ekeberg, Tomas; Fromme, Petra; Hajdu, Janos; Hanke, Max Felix; Hart, Philip; Hogue, Brenda G; Hosseinizadeh, Ahmad; Kim, Yoonhee; Kirian, Richard A; Kurta, Ruslan P; Larsson, Daniel S D; Duane Loh, N; Maia, Filipe R N C; Mancuso, Adrian P; Mühlig, Kerstin; Munke, Anna; Nam, Daewoong; Nettelblad, Carl; Ourmazd, Abbas; Rose, Max; Schwander, Peter; Seibert, Marvin; Sellberg, Jonas A; Song, Changyong; Spence, John C H; Svenda, Martin; Van der Schot, Gijs; Vartanyants, Ivan A; Williams, Garth J; Xavier, P Lourdu

2017-06-27

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65-70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. The data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency.

The Atacama Large Millimeter Array (ALMA)

NASA Astrophysics Data System (ADS)

1999-06-01

The Atacama Large Millimeter Array (ALMA) is the new name [2] for a giant millimeter-wavelength telescope project. As described in the accompanying joint press release by ESO and the U.S. National Science Foundation , the present design and development phase is now a Europe-U.S. collaboration, and may soon include Japan. ALMA may become the largest ground-based astronomy project of the next decade after VLT/VLTI, and one of the major new facilities for world astronomy. ALMA will make it possible to study the origins of galaxies, stars and planets. As presently envisaged, ALMA will be comprised of up to 64 12-meter diameter antennas distributed over an area 10 km across. ESO PR Photo 24a/99 shows an artist's concept of a portion of the array in a compact configuration. ESO PR Video Clip 03/99 illustrates how all the antennas will move in unison to point to a single astronomical object and follow it as it traverses the sky. In this way the combined telescope will produce astronomical images of great sharpness and sensitivity [3]. An exceptional site For such observations to be possible the atmosphere above the telescope must be transparent at millimeter and submillimeter wavelengths. This requires a site that is high and dry, and a high plateau in the Atacama desert of Chile, probably the world's driest, is ideal - the next best thing to outer space for these observations. ESO PR Photo 24b/99 shows the location of the chosen site at Chajnantor, at 5000 meters altitude and 60 kilometers east of the village of San Pedro de Atacama, as seen from the Space Shuttle during a servicing mission of the Hubble Space Telescope. ESO PR Photo 24c/99 and ESO PR Photo 24d/99 show a satellite image of the immediate vicinity and the site marked on a map of northern Chile. ALMA will be the highest continuously operated observatory in the world. The stark nature of this extreme site is well illustrated by the panoramic view in ESO PR Photo 24e/99. High sensitivity and sharp images ALMA

A Portrait of One Hundred Thousand and One Galaxies

NASA Astrophysics Data System (ADS)

2002-08-01

Rich and Inspiring Experience with NGC 300 Images from the ESO Science Data Archive Summary A series of wide-field images centred on the nearby spiral galaxy NGC 300 , obtained with the Wide-Field Imager (WFI) on the MPG/ESO 2.2-m telescope at the La Silla Observatory , have been combined into a magnificent colour photo. These images have been used by different groups of astronomers for various kinds of scientific investigations, ranging from individual stars and nebulae in NGC 300, to distant galaxies and other objects in the background. This material provides an interesting demonstration of the multiple use of astronomical data, now facilitated by the establishment of extensively documented data archives, like the ESO Science Data Archive that now is growing rapidly and already contains over 15 Terabyte. Based on the concept of Astronomical Virtual Observatories (AVOs) , the use of archival data sets is on the rise and provides a large number of scientists with excellent opportunities for front-line investigations without having to wait for precious observing time. In addition to presenting a magnificent astronomical photo, the present account also illustrates this important new tool of the modern science of astronomy and astrophysics. PR Photo 18a/02 : WFI colour image of spiral galaxy NGC 300 (full field) . PR Photo 18b/02 : Cepheid stars in NGC 300 PR Photo 18c/02 : H-alpha image of NGC 300 PR Photo 18d/02 : Distant cluster of galaxies CL0053-37 in the NGC 300 field PR Photo 18e/02 : Dark matter distribution in CL0053-37 PR Photo 18f/02 : Distant, reddened cluster of galaxies in the NGC 300 field PR Photo 18g/02 : Distant galaxies, seen through the outskirts of NGC 300 PR Photo 18h/02 : "The View Beyond" ESO PR Photo 18a/02 ESO PR Photo 18a/02 [Preview - JPEG: 400 x 412 pix - 112k] [Normal - JPEG: 1200 x 1237 pix - 1.7M] [Hi-Res - JPEG: 4000 x 4123 pix - 20.3M] Caption : PR Photo 18a/02 is a reproduction of a colour-composite image of the nearby spiral galaxy

New Paranal Views

NASA Astrophysics Data System (ADS)

2001-01-01

Telescope (VST) as well as the location known as the "NTT Peak", now under consideration for the installation of the 4-m VISTA telescope. The last images are from to the second 8.2-m Unit Telescope, KUEYEN, that has been in full use by the astronomers with the UVES and FORS2 instruments since April 2000. ESO PR Photo 04a/01 ESO PR Photo 04a/01 [Preview - JPEG: 466 x 400 pix - 58k] [Normal - JPEG: 931 x 800 pix - 688k] [Hires - JPEG: 3000 x 2577 pix - 7.6M] Caption : PR Photo 04a/01 shows an afternoon view from the Paranal summit towards East, with the Base Camp and the new Residencia on the slope to the right, above the valley in the shadow of the mountain. ESO PR Photo 04b/01 ESO PR Photo 04b/01 [Preview - JPEG: 791 x 400 pix - 89k] [Normal - JPEG: 1582 x 800 pix - 1.1Mk] [Hires - JPEG: 3000 x 1517 pix - 3.6M] PR Photo 04b/01 shows the ramp leading to the main entrance to the partly subterranean Residencia , with the steel skeleton for the dome over the central area in place. ESO PR Photo 04c/01 ESO PR Photo 04c/01 [Preview - JPEG: 498 x 400 pix - 65k] [Normal - JPEG: 995 x 800 pix - 640k] [Hires - JPEG: 3000 x 2411 pix - 6.6M] PR Photo 04c/01 is an indoor view of the reception hall under the dome, looking towards the main entrance. ESO PR Photo 04d/01 ESO PR Photo 04d/01 [Preview - JPEG: 472 x 400 pix - 61k] [Normal - JPEG: 944 x 800 pix - 632k] [Hires - JPEG: 3000 x 2543 pix - 5.8M] PR Photo 04d/01 shows the ramps from the reception area towards the rooms. The VLT Interferometer The Delay Lines consitute a most important element of the VLT Interferometer , cf. PR Photos 26a-e/00. At this moment, two Delay Lines are operational on site. A third system will be integrated early this year. The VLTI Delay Line is located in an underground tunnel that is 168 metres long and 8 metres wide. This configuration has been designed to accommodate up to eight Delay Lines, including their transfer optics in an ideal environment: stable temperature, high degree of cleanliness, low

Induction of CD8 T-cell responses restricted to multiple HLA class I alleles in a cancer patient by immunization with a 20-mer NY-ESO-1f (NY-ESO-1 91-110) peptide.

PubMed

Eikawa, Shingo; Kakimi, Kazuhiro; Isobe, Midori; Kuzushima, Kiyotaka; Luescher, Immanuel; Ohue, Yoshihiro; Ikeuchi, Kazuhiro; Uenaka, Akiko; Nishikawa, Hiroyoshi; Udono, Heiichiro; Oka, Mikio; Nakayama, Eiichi

2013-01-15

Immunogenicity of a long 20-mer NY-ESO-1f peptide vaccine was evaluated in a lung cancer patient TK-f01, immunized with the peptide with Picibanil OK-432 and Montanide ISA-51. We showed that internalization of the peptide was necessary to present CD8 T-cell epitopes on APC, contrasting with the direct presentation of the short epitope. CD8 T-cell responses restricted to all five HLA class I alleles were induced in the patient after the peptide vaccination. Clonal analysis showed that B*35:01 and B*52:01-restricted CD8 T-cell responses were the two dominant responses. The minimal epitopes recognized by A*24:02, B*35:01, B*52:01 and C*12:02-restricted CD8 T-cell clones were defined and peptide/HLA tetramers were produced. NY-ESO-1 91-101 on A*24:02, NY-ESO-1 92-102 on B*35:01, NY-ESO-1 96-104 on B*52:01 and NY-ESO-1 96-104 on C*12:02 were new epitopes first defined in this study. Identification of the A*24:02 epitope is highly relevant for studying the Japanese population because of its high expression frequency (60%). High affinity CD8 T-cells recognizing tumor cells naturally expressing the epitopes and matched HLA were induced at a significant level. The findings suggest the usefulness of a long 20-mer NY-ESO-1f peptide harboring multiple CD8 T-cell epitopes as an NY-ESO-1 vaccine. Characterization of CD8 T-cell responses in immunomonitoring using peptide/HLA tetramers revealed that multiple CD8 T-cell responses comprised the dominant response. Copyright © 2012 UICC.

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

DOE PAGES

Reddy, Hemanth K. N.; Yoon, Chun Hong; Aquila, Andrew; ...

2017-06-27

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65–70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. As a result, themore » data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency.« less

CUBES: cassegrain U-band Brazil-ESO spectrograph

NASA Astrophysics Data System (ADS)

Barbuy, B.; Bawden Macanhan, V.; Bristow, P.; Castilho, B.; Dekker, H.; Delabre, B.; Diaz, M.; Gneiding, C.; Kerber, F.; Kuntschner, H.; La Mura, G.; Maciel, W.; Meléndez, J.; Pasquini, L.; Pereira, C. B.; Petitjean, P.; Reiss, R.; Siqueira-Mello, C.; Smiljanic, R.; Vernet, J.

2014-11-01

CUBES is a high-efficiency, medium-resolution ( R˜20,000) ground based UV (300-400 nm) spectrograph, to be installed in the cassegrain focus of one of ESO's VLT unit telescopes in 2017/18. The CUBES project is a joint venture between ESO and IAG/USP, and LNA/MCTI. CUBES will provide access to a wealth of new and relevant information for stellar as well as extragalactic sources. Main science cases include the study of beryllium and heavy elements in metal-poor stars, the direct determination of carbon, nitrogen and oxygen abundances by study of molecular bands in the UV range, as well as the study of active galactic nuclei and the quasar absorption lines. With a streamlined modern instrument design, high efficiency dispersing elements and UV-sensitive detectors, it will give a significant gain in sensitivity over existing ground based medium-high resolution spectrographs, enabling vastly increased sample sizes accessible to the astronomical community. We present here a brief overview of the project including the status, science cases and a discussion of the design options.

First-Ever Census of Variable Mira-Type Stars in Galaxy Outside the Local Group

NASA Astrophysics Data System (ADS)

2003-05-01

First-Ever Census of Variable Mira-Type Stars in Galaxy Outsidethe Local Group Summary An international team led by ESO astronomer Marina Rejkuba [1] has discovered more than 1000 luminous red variable stars in the nearby elliptical galaxy Centaurus A (NGC 5128) . Brightness changes and periods of these stars were measured accurately and reveal that they are mostly cool long-period variable stars of the so-called "Mira-type" . The observed variability is caused by stellar pulsation. This is the first time a detailed census of variable stars has been accomplished for a galaxy outside the Local Group of Galaxies (of which the Milky Way galaxy in which we live is a member). It also opens an entirely new window towards the detailed study of stellar content and evolution of giant elliptical galaxies . These massive objects are presumed to play a major role in the gravitational assembly of galaxy clusters in the Universe (especially during the early phases). This unprecedented research project is based on near-infrared observations obtained over more than three years with the ISAAC multi-mode instrument at the 8.2-m VLT ANTU telescope at the ESO Paranal Observatory . PR Photo 14a/03 : Colour image of the peculiar galaxy Centaurus A . PR Photo 14b/03 : Location of the fields in Centaurus A, now studied. PR Photo 14c/03 : "Field 1" in Centaurus A (visual light; FORS1). PR Photo 14d/03 : "Field 2" in Centaurus A (visual light; FORS1). PR Photo 14e/03 : "Field 1" in Centaurus A (near-infrared; ISAAC). PR Photo 14f/03 : "Field 2" in Centaurus A (near-infrared; ISAAC). PR Photo 14g/03 : Light variation of six variable stars in Centaurus A PR Photo 14h/03 : Light variation of stars in Centaurus A (Animated GIF) PR Photo 14i/03 : Light curves of four variable stars in Centaurus A. Mira-type variable stars Among the stars that are visible in the sky to the unaided eye, roughly one out of three hundred (0.3%) displays brightness variations and is referred to by astronomers as a

Comparison of (99m)Tc-labeled PR81 and its F(ab')₂ fragments as radioimmunoscintigraphy agents for breast cancer imaging.

PubMed

Salouti, Mojtaba; Babaei, Mohammad Hossein; Rajabi, Hossein; Foroutan, Haleh; Rasaee, Mohammad Javad; Rajabi, Ahmad Bitarafan; Mohammadnejad, Javad; Shafiee, Mohammad; Mazidi, Mohammad; Daha, Fariba Johari

2011-02-01

We digested anti-MUC1 monoclonal antibody PR81 to produce F(ab')₂ fragments. A comparison was performed between the two radiolabeled PR81 and F(ab')₂ fragments for breast tumor imaging in a mouse model. The optimum conditions for pepsin digestion of PR81 were investigated in terms of enzymes: antibody ratio, digestion time duration and preserved immunoreactivity of the produced fragments. The F(ab')₂ fragments were labeled with Technetium-99m using HYNIC as a chelator and tricine as a co-ligand. The immunoreactivity of the complexes was assessed by radioimmunoassay using MCF7 cells. Biodistribution and imaging studies were performed in female BALB/c mice with breast tumor xenograft at 4, 8 and 24 h post-administration. The PR81 was labeled with technetium-99m in the same way for comparison. The optimum time duration for PR81 digestion was found to be 28 h at an enzyme:antibody weight ratio of 1:20 that resulted in 95.2 ± 4.7% purity. The labeling of intact PR81 and its F(ab')₂ fragments were 87.6 ± 4.2 and 76.1 ± 3.3% after 1 h, respectively (p value <0.05). The percentage of immunoreactivity of F(ab')₂ fragments and intact PR81 were 75.4 ± 2.1% and 85.7 ± 2.9%, respectively (p value <0.05). The biodistribution and imaging studies demonstrated localization of the fragments at 4 h post-administration with high sensitivity and specificity. The results showed that F(ab')₂ fragment of PR81 is more suitable than intact PR81 for safer and more rapid detection of human breast cancer.

A 3000 TNOs Survey Project at ESO La Silla

NASA Astrophysics Data System (ADS)

Boehnhardt, H.; Hainaut, O.

We propose a wide-shallow TNO search to be done with the Wide Field Imager (WFI) instrument at the 2.2m MPG/ESO telescope in La Silla/Chile. The WFI is a half-deg camera equipped with an 8kx8k CCD (0.24 arcsec/pixel). The telescope can support excellent seeing quality down to 0.5arcsec FWHM. A TNO search pilot project was run with the 2.2m+WFI in 1999: images with just 1.6sdeg sky coverage and typically 24mag limiting brightness revealed 6 new TNOs when processed with our new automatic detection program MOVIE. The project is now continued on a somewhat larger scale in order to find more TNOs and to fine-tune the operational environment for a full automatic on-line detection, astrometry and photometry of the objects at the telescope. The future goal is to perform - with the 2.2m+WFI and in an international colaboration - an even larger TNO survey over a major part of the sky (typically 2000sdeg in and out of Ecliptic) down to 24mag. Follow-up astrometry and photometry of the expected more than 3000 discovered objects will secure their orbital and physical characterisation for synoptic dynamical and taxonomic studies of the Transneptunian population.

The Capodimonte Deep Field

NASA Astrophysics Data System (ADS)

2001-04-01

A Window towards the Distant Universe Summary The Osservatorio Astronomico Capodimonte Deep Field (OACDF) is a multi-colour imaging survey project that is opening a new window towards the distant universe. It is conducted with the ESO Wide Field Imager (WFI) , a 67-million pixel advanced camera attached to the MPG/ESO 2.2-m telescope at the La Silla Observatory (Chile). As a pilot project at the Osservatorio Astronomico di Capodimonte (OAC) [1], the OACDF aims at providing a large photometric database for deep extragalactic studies, with important by-products for galactic and planetary research. Moreover, it also serves to gather experience in the proper and efficient handling of very large data sets, preparing for the arrival of the VLT Survey Telescope (VST) with the 1 x 1 degree 2 OmegaCam facility. PR Photo 15a/01 : Colour composite of the OACDF2 field . PR Photo 15b/01 : Interacting galaxies in the OACDF2 field. PR Photo 15c/01 : Spiral galaxy and nebulous object in the OACDF2 field. PR Photo 15d/01 : A galaxy cluster in the OACDF2 field. PR Photo 15e/01 : Another galaxy cluster in the OACDF2 field. PR Photo 15f/01 : An elliptical galaxy in the OACDF2 field. The Capodimonte Deep Field ESO PR Photo 15a/01 ESO PR Photo 15a/01 [Preview - JPEG: 400 x 426 pix - 73k] [Normal - JPEG: 800 x 851 pix - 736k] [Hi-Res - JPEG: 3000 x 3190 pix - 7.3M] Caption : This three-colour image of about 1/4 of the Capodimonte Deep Field (OACDF) was obtained with the Wide-Field Imager (WFI) on the MPG/ESO 2.2-m telescope at the la Silla Observatory. It covers "OACDF Subfield no. 2 (OACDF2)" with an area of about 35 x 32 arcmin 2 (about the size of the full moon), and it is one of the "deepest" wide-field images ever obtained. Technical information about this photo is available below. With the comparatively few large telescopes available in the world, it is not possible to study the Universe to its outmost limits in all directions. Instead, astronomers try to obtain the most detailed

VLTI First Fringes with Two Auxiliary Telescopes at Paranal

NASA Astrophysics Data System (ADS)

2005-03-01

World's Largest Interferometer with Moving Optical Telescopes on Track Summary The Very Large Telescope Interferometer (VLTI) at Paranal Observatory has just seen another extension of its already impressive capabilities by combining interferometrically the light from two relocatable 1.8-m Auxiliary Telescopes. Following the installation of the first Auxiliary Telescope (AT) in January 2004 (see ESO PR 01/04), the second AT arrived at the VLT platform by the end of 2004. Shortly thereafter, during the night of February 2 to 3, 2005, the two high-tech telescopes teamed up and quickly succeeded in performing interferometric observations. This achievement heralds an era of new scientific discoveries. Both Auxiliary Telescopes will be offered from October 1, 2005 to the community of astronomers for routine observations, together with the MIDI instrument. By the end of 2006, Paranal will be home to four operational ATs that may be placed at 30 different positions and thus be combined in a very large number of ways ("baselines"). This will enable the VLTI to operate with enormous flexibility and, in particular, to obtain extremely detailed (sharp) images of celestial objects - ultimately with a resolution that corresponds to detecting an astronaut on the Moon. PR Photo 07a/05: Paranal Observing Platform with AT1 and AT2 PR Photo 07b/05: AT1 and AT2 with Open Domes PR Photo 07c/05: Evening at Paranal with AT1 and AT2 PR Photo 07d/05: AT1 and AT2 under the Southern Sky PR Photo 07e/05: First Fringes with AT1 and AT2 PR Video Clip 01/05: Two ATs at Paranal (Extract from ESO Newsreel 15) A Most Advanced Device ESO PR Video 01/05 ESO PR Video 01/05 Two Auxiliary Telescopes at Paranal [QuickTime: 160 x 120 pix - 37Mb - 4:30 min] [QuickTime: 320 x 240 pix - 64Mb - 4:30 min] ESO PR Photo 07a/05 ESO PR Photo 07a/05 [Preview - JPEG: 493 x400 pix - 44k] [Normal - JPEG: 985 x 800 pix - 727k] [HiRes - JPEG: 5000 x 4060 pix - 13.8M] Captions: ESO PR Video Clip 01/05 is an extract from

MHC class II/ESO tetramer-based generation of in vitro primed anti-tumor T-helper lines for adoptive cell therapy of cancer.

PubMed

Poli, Caroline; Raffin, Caroline; Dojcinovic, Danijel; Luescher, Immanuel; Ayyoub, Maha; Valmori, Danila

2013-02-01

Generation of tumor-antigen specific CD4(+) T-helper (T(H)) lines through in vitro priming is of interest for adoptive cell therapy of cancer, but the development of this approach has been limited by the lack of appropriate tools to identify and isolate low frequency tumor antigen-specific CD4(+) T cells. Here, we have used recently developed MHC class II/peptide tetramers incorporating an immunodominant peptide from NY-ESO-1 (ESO), a tumor antigen frequently expressed in different human solid and hematologic cancers, to implement an in vitro priming platform allowing the generation of ESO-specific T(H) lines. We isolated phenotypically defined CD4(+) T-cell subpopulations from circulating lymphocytes of DR52b(+) healthy donors by flow cytometry cell sorting and stimulated them in vitro with peptide ESO(119-143), autologous APC and IL-2. We assessed the frequency of ESO-specific cells in the cultures by staining with DR52b/ESO(119-143) tetramers (ESO-tetramers) and TCR repertoire of ESO-tetramer(+) cells by co-staining with TCR variable β chain (BV) specific antibodies. We isolated ESO-tetramer(+) cells by flow cytometry cell sorting and expanded them with PHA, APC and IL-2 to generate ESO-specific T(H) lines. We characterized the lines for antigen recognition, by stimulation with ESO peptide or recombinant protein, cytokine production, by intracellular staining using specific antibodies, and alloreactivity, by stimulation with allo-APC. Using this approach, we could consistently generate ESO-tetramer(+) T(H) lines from conventional CD4(+)CD25(-) naïve and central memory populations, but not from effector memory populations or CD4(+)CD25(+) Treg. In vitro primed T(H) lines recognized ESO with affinities comparable to ESO-tetramer(+) cells from patients immunized with an ESO vaccine and used a similar TCR repertoire. In this study, using MHC class II/ESO tetramers, we have implemented an in vitro priming platform allowing the generation of ESO

Cosmic Interactions

NASA Astrophysics Data System (ADS)

2008-01-01

An image based on data taken with ESO's Very Large Telescope reveals a triplet of galaxies intertwined in a cosmic dance. ESO PR Photo 02/08 ESO PR Photo 02/08 NGC 7173, 7174, and 7176 The three galaxies, catalogued as NGC 7173 (top), 7174 (bottom right) and 7176 (bottom left), are located 106 million light-years away towards the constellation of Piscis Austrinus (the 'Southern Fish'). NGC 7173 and 7176 are elliptical galaxies, while NGC 7174 is a spiral galaxy with quite disturbed dust lanes and a long, twisted tail. This seems to indicate that the two bottom galaxies - whose combined shape bears some resemblance to that of a sleeping baby - are currently interacting, with NGC 7176 providing fresh material to NGC 7174. Matter present in great quantity around the triplet's members also points to the fact that NGC 7176 and NGC 7173 have interacted in the past. Astronomers have suggested that the three galaxies will finally merge into a giant 'island universe', tens to hundreds of times as massive as our own Milky Way. ESO PR Photo 02/08 ESO PR Photo 02b/08 NGC 7173, 7174, and 7176 The triplet is part of a so-called 'Compact Group', as compiled by Canadian astronomer Paul Hickson in the early 1980s. The group, which is the 90th entry in the catalogue and is therefore known as HCG 90, actually contains four major members. One of them - NGC 7192 - lies above the trio, outside of this image, and is another peculiar spiral galaxy. Compact groups are small, relatively isolated, systems of typically four to ten galaxies in close proximity to one another. Another striking example is Robert's Quartet. Compact groups are excellent laboratories for the study of galaxy interactions and their effects, in particular the formation of stars. As the striking image reveals, there are many other galaxies in the field. Some are distant ones, while others seem to be part of the family. Studies made with other telescopes have indeed revealed that the HCG 90 group contains 16 members

The ESO Observing Programmes Committee

NASA Astrophysics Data System (ADS)

Westerlund, B. E.

1982-06-01

Since 1978 the ESO Observing Programmes Committee (OPC) has "the function to inspect and rank the proposals made for observing programmes at La Silla, and thereby to advise the Director General on the distribution of observing time". The members (one from each member country) and their alternates are nominated by the respective national committees for five-year terms (not immediately renewable). The terms are staggered so that each year one or two persons are replaced. The Chairman is appointed annually by the Council. He is invited to attend Council meetings and to report to its members.

Man-made Star Shines in the Southern Sky

NASA Astrophysics Data System (ADS)

2006-02-01

Scientists celebrate another major milestone at Cerro Paranal in Chile, home of ESO's Very Large Telescope array. Thanks to their dedicated efforts, they were able to create the first artificial star in the Southern Hemisphere, allowing astronomers to study the Universe in the finest detail. This artificial laser guide star makes it possible to apply adaptive optics systems, that counteract the blurring effect of the atmosphere, almost anywhere in the sky. ESO PR Photo 07a/06 ESO PR Photo 07a/06 First Light of the VLT Laser Guide Star On 28 January 2006, at 23:07 local time, a laser beam of several watts was launched from Yepun, the fourth 8.2m Unit Telescope of the Very Large Telescope, producing an artificial star, 90 km up in the atmosphere. Despite this star being about 20 times fainter than the faintest star that can be seen with the unaided eye, it is bright enough for the adaptive optics to measure and correct the atmosphere's blurring effect. The event was greeted with much enthusiasm and happiness by the people in the control room of one of the most advanced astronomical facilities in the world. It was the culmination of five years of collaborative work by a team of scientists and engineers from ESO and the Max Planck Institutes for Extraterrestrial Physics in Garching and for Astronomy in Heidelberg, Germany. After more than one month of integration on site with the invaluable support of the Paranal Observatory staff, the VLT Laser Guide Star Facility saw First Light and propagated into the sky a 50cm wide, vivid, beautifully yellow beam. ESO PR Photo 07b/06 ESO PR Photo 07b/06 An Artificial Star Above Paranal "This event tonight marks the beginning of the Laser Guide Star Adaptive Optics era for ESO's present and future telescopes", said Domenico Bonaccini Calia, Head of the Laser Guide Star group at ESO and LGSF Project Manager. Normally, the achievable image sharpness of a ground-based telescope is limited by the effect of atmospheric turbulence. This

Tips for the PR Chairman for Education Associations. PR Bookshelf No. 2.

ERIC Educational Resources Information Center

National Education Association, Washington, DC.

This booklet is intended to aid leaders of local education associations in developing a continuing public relations (PR) program aimed at establishing and maintaining a favorable public image for teachers. Although it offers useful guidelines for developing a PR program, the booklet does not contain lists of specific things to do. Instead, it…

Coherent Soft X-ray Diffraction Imaging of Coliphage PR772 at the Linac Coherent Light Source

DOE Data Explorer

Reddy, Hemanth, K.N.

2017-01-05

A dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source.

The ESO Scientific and Technical Committee.

NASA Astrophysics Data System (ADS)

Léna, P.

1982-03-01

Since 1978, the structure of ESO involves a Scientific and Technical Committee (STC) which advises the Council on scientific and technical matters. This committee meets twice a year, usually at Garehing; its members are nominated by the Council and their term is 4 years. The STC has 10 members, who are as evenly distributed as possible among member countries, although indeed mainly chosen for their scientific abilities. The chairman is invited to attend Council meetings and to report to the members.

Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1c259T cells in Synovial Sarcoma.

PubMed

D'Angelo, Sandra P; Melchiori, Luca; Merchant, Melinda S; Bernstein, Donna B; Glod, John; Kaplan, Rosandra N; Grupp, Stephan A; Tap, William D; Chagin, Karen; Binder, Gwendolyn K; Basu, Samik; Lowther, Daniel E; Wang, Ruoxi; Bath, Natalie; Tipping, Alex; Betts, Gareth; Ramachandran, Indu; Navenot, Jean-Marc; Zhang, Hua; Wells, Daniel K; Van Winkle, Erin; Kari, Gabor; Trivedi, Trupti; Holdich, Tom; Pandite, Lini N; Amado, Rafael; Mackall, Crystal L

2018-06-11

We evaluated safety and activity of autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T cell receptor (TCR) recognizing an HLA-A2-restricted NY-ESO-1/LAGE-1a-derived peptide, in patients with metastatic synovial sarcoma (NY-ESO-1c259T cells). Confirmed antitumor responses occurred in 50% of patients (6/12) and were characterized by tumor shrinkage over several months. Circulating NY-ESO-1c259T cells were present post-infusion in all patients and persisted for at least 6 months in all responders. Most infused NY-ESO-1c259T cells exhibited an effector memory phenotype following the ex vivo expansion, but the persisting pools comprised largely central memory and stem cell memory subsets, which remained polyfunctional and showed no evidence for T cell exhaustion despite persistent tumor burdens. Next generation sequencing of endogenous TCRs in CD8+ NY-ESO-1c259T cells revealed clonal diversity without contraction over time. These data suggest that regenerative pools of NY-ESO-1c259T cells produced a continuing supply of effector cells to mediate sustained, clinically meaningful antitumor effects. Copyright ©2018, American Association for Cancer Research.

Multicentric analysis of performance after major lung resections by using the European Society Objective Score (ESOS).

PubMed

Brunelli, Alessandro; Varela, Gonzalo; Van Schil, Paul; Salati, Michele; Novoa, Nuria; Hendriks, Jeroen M; Jimenez, Marcelo F; Lauwers, Patrick

2008-02-01

Outcome endpoints are still the most widely used indicators of performance. However, they need to be risk-adjusted in order to be reliable instruments of audit. Recently, the European Society Objective Score (ESOS) was developed from the online European Thoracic Surgery Database as an audit tool. In this study, we applied for the first time the ESOS.01 to assess the performance of three European thoracic surgery units during three successive years of activity. This study is a retrospective analysis performed on prospective databases. We analysed 695 patients submitted to pneumonectomy (117) or lobectomy (578) for lung neoplasm at three European dedicated thoracic surgery units (unit A 264 patients, unit B 262, unit C 169) from January 2004 through December 2006. Qualified thoracic surgeons performed all the operations. No patients in this series were in the original ESOS development set. ESOS.01 was used to estimate the risk of in-hospital mortality in all patients. Observed and predicted mortality rates were then compared within each unit by the z-test. Cumulative observed mortality rates in units A, B and C were 2.3% (six cases), 2.7% (seven cases) and 4.1% (seven cases), respectively. We were not able to find statistically significant differences between observed and ESOS-predicted mortality rates. The comparison of risk-adjusted mortality rates between units did not show significant differences (unit A 3.9%, unit B 3.3%, unit C 5.6%). The use of ESOS.01 revealed that the performances of all units were in line with the predicted ones during each period under analysis and did not differ between each other. The results of our study warrant future efforts to refine the ESOS model and to develop other risk-adjusted outcome indicators with the aim to establish European benchmarks of performance.

Black Hole in Search of a Home

NASA Astrophysics Data System (ADS)

2005-09-01

), having a redshift of 0.135, is more fuzzy and shows only hints of spiral arms. Although these particular objects are rather close to us and constitute therefore easy targets, their host would still be perfectly visible at much higher redshift, including at distances as large as the one of HE0450-2958 (z=0.285). The observations were done with the ACS camera on the HST. ESO PR Photo 28b/05 ESO PR Photo 28b/05 The Quasar without a Home: HE0450-2958 [Preview - JPEG: 400 x 760 pix - 53k] [Normal - JPEG: 800 x 1520 pix - 197k] [Full Res - JPEG: 1718 x 3265 pix - 1.5M] Caption of ESO PR Photo 28b/05: (Left) HST image of the z=0.285 quasar HE0450-2958. No obvious host galaxy centred on the quasar is seen. Only a strongly disturbed and star forming companion galaxy is seen near the top of the image. (Right) Same image shown after applying an efficient image sharpening method known as MCS-deconvolution. In contrast to the usual cases, as the ones shown in ESO PR Photo 28a/05, the quasar is not situated at the centre of an extended host galaxy, but on the edge of a compact structure, whose spectra (see ESO PR Photo 28c/05) show it to be composed of gas ionised by the quasar radiation. This gas may have been captured through a collision with the star-forming galaxy. The star indicated on the figure is a nearby galactic star seen by chance in the field of view. To overcome this problem, the astronomers devised a new and highly efficient strategy. Using ESO's VLT for spectroscopy and HST for imagery, they observed their quasars at the same time as a reference star. Simultaneous observation of a star allowed them to measure at best the shape of the quasar point source on spectra and images, and further to separate the quasar light from the other contribution, i.e. from the underlying galaxy itself. This very powerful image and spectra sharpening method ("MCS deconvolution") was applied to these data in order to detect the finest details of the host galaxy (see e.g. ESO PR 19

ESDIS Standards Office (ESO): Requirements, Standards and Practices

NASA Technical Reports Server (NTRS)

Mitchell, Andrew E.; Mcinerney, Mark Allen; Enloe, Yonsok K.; Conover, Helen T.; Doyle, Allan

2016-01-01

The ESDIS Standards Office assists the ESDIS Project in formulating standards policy for NASA Earth Science Data Systems (ESDS), coordinates standards activities within ESDIS, and provides technical expertise and assistance with standards related tasks within the NASA Earth Science Data System Working Groups (ESDSWG). This poster summarizes information found on the earthdata.nasa.gov site that describes the ESO.

First Light with a 67-Million-Pixel WFI Camera

NASA Astrophysics Data System (ADS)

1999-01-01

tests with the WFI in order to arrive at the optimum adjustment of the camera at the telescope. We show here two of these that illustrate the great potential of this new facility. Spiral Galaxy NGC 253 ESO PR Photo 02a/99 ESO PR Photo 02a/99 [Preview - JPEG: 800x850 pix - 205k] [High-Res - JPEG: 4000 x 4252 pix - 3.0Mb] ESO PR Photo 02b/99 ESO PR Photo 02b/99 [Preview - JPEG: 800x870 pix - 353k] [High-Res - JPEG: 2200 x 2393 pix - 2.0Mb] Caption to PR Photos 02a/99 and 02b/99 : These photos show a sky field around the Spiral Galaxy NGC 253 (Type Sc) seen nearly edge-on. It is located in the southern constellation Sculptor at a distance of about 8 million light-years. The image is the sum of five 5-min exposures through a blue (B-band) optical filtre. They were slightly offset with respect to each other so that the small gaps between the eight CCD's of the mosaic are no longer visible. This image also shows the faint trails of 2 artificial satellites. In PR Photo 02a/99 , the full WFI field-of-view is reproduced, while the sub-field in PR Photo 02b/99 contains some fainter and smaller background galaxies. Many of the quite numerous and small, slightly fuzzy objects are undoubtedly globular clusters of NGC 253. Technical information: The image processing consisted of de-biassing, flat-fielding, and removal (by interpolation) of some bad columns. The full-width-half-maximum (FWHM) of stellar images is about 1.0 arcsec. PR Photo 02a/99 was rebinned (2x2) to 4kx4k size and sampling 0.48 arcsec/pixel. PR Photo 02b/99 is a subimage of the former, but at the full original sampling of 0.24 arcsec/pixel. It covers about 2kx2k, or about 1/16 of the full field. North is up and East is left. The observations were made on December 17, 1998. The Waning Moon ESO PR Photo 02c/99 ESO PR Photo 02c/99 [Preview - JPEG: 800 x 1245 pix - 242k] [High-Res - JPEG: 3000 x 4667 pix - 2.3Mb] ESO PR Photo 02d/99 ESO PR Photo 02d/99 [Preview - JPEG: 800 x 1003 pix - 394k] [High-Res - JPEG: 3000 x

CERN, ESA and ESO Launch "Physics On Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

Physics is everywhere . The laws of physics govern the Universe, the Sun, the Earth and even our own lives. In today's rapidly developing society, we are becoming increasingly dependent on high technology - computers, transport, and communication are just some of the key areas that are the result of discoveries by scientists working in physics. But how much do the citizens of Europe really know about physics? Here is a unique opportunity to learn more about this elusive subject! [Go to Physics On Stage Website] Beginning in February 2000, three major European research organisations are organising a unique Europe-wide programme to raise the public awareness of physics and related sciences. "Physics on Stage" is launched by the European Laboratory for Particle Physics (CERN) , the European Space Agency (ESA) and the European Southern Observatory (ESO) , with support from the European Union. Other partners are the European Physical Society (EPS) and the European Association for Astronomy Education (EAAE). This exciting programme is part of the European Week for Science and Technology and will culminate in a Science Festival during November 6-11, 2000, on the CERN premises at the French-Swiss border near Geneva. Why "Physics on Stage"? The primary goal of "Physics on Stage" is to counteract the current decline in interest and knowledge about physics among Europe's citizens by means of a series of highly visible promotional activities. It will bring together leading scientists and educators, government bodies and the media, to confront the diminishing attraction of physics to young people and to develop strategies to reverse this trend. The objective in the short term is to infuse excitement and to provide new educational materials. In the longer term, "Physics on Stage" will generate new developments by enabling experts throughout Europe to meet, exchange and innovate. "Physics on Stage" in 22 European Countries "Physics on Stage" has been initiated in 22 European

ESO 50th Anniversary Gala Dinner

NASA Astrophysics Data System (ADS)

Sirey, R.

2012-12-01

To formally mark the 50th anniversary of the signing of the ESO Convention, a gala dinner was held in the Munich Residenz. A brief report of the event is presented and the speeches are reproduced. The speakers were the President of the Council, Xavier Barcons; the German Minister for Education and Research, Prof. Dr Annette Schavan; the Bavarian State Minister for Science, Research and the Arts, Dr Wolfgang Heubisch; physics Nobel Laureate, Brian Schmidt; the current Director General, Tim de Zeeuw and the Chilean Minister of Foreign Affairs, Alfredo Moreno Charme.

Rubble-Pile Minor Planet Sylvia and Her Twins

NASA Astrophysics Data System (ADS)

2005-08-01

VLT NACO Instrument Helps Discover First Triple Asteroid One of the thousands of minor planets orbiting the Sun has been found to have its own mini planetary system. Astronomer Franck Marchis (University of California, Berkeley, USA) and his colleagues at the Observatoire de Paris (France) [1] have discovered the first triple asteroid system - two small asteroids orbiting a larger one known since 1866 as 87 Sylvia [2]. "Since double asteroids seem to be common, people have been looking for multiple asteroid systems for a long time," said Marchis. "I couldn't believe we found one." The discovery was made with Yepun, one of ESO's 8.2-m telescopes of the Very Large Telescope Array at Cerro Paranal (Chile), using the outstanding image' sharpness provided by the adaptive optics NACO instrument. Via the observatory's proven "Service Observing Mode", Marchis and his colleagues were able to obtain sky images of many asteroids over a six-month period without actually having to travel to Chile. ESO PR Photo 25a/05 ESO PR Photo 25a/05 Orbits of Twin Moonlets around 87 Sylvia [Preview - JPEG: 400 x 516 pix - 145k] [Normal - JPEG: 800 x 1032 pix - 350k] ESO PR Photo 25b/05 ESO PR Photo 25b/05 Artist's impression of the triple asteroid system [Preview - JPEG: 420 x 400 pix - 98k] [Normal - JPEG: 849 x 800 pix - 238k] [Full Res - JPEG: 4000 x 3407 pix - 3.7M] [Full Res - TIFF: 4000 x 3000 pix - 36.0M] Caption: ESO PR Photo 25a/05 is a composite image showing the positions of Remus and Romulus around 87 Sylvia on 9 different nights as seen on NACO images. It clearly reveals the orbits of the two moonlets. The inset shows the potato shape of 87 Sylvia. The field of view is 2 arcsec. North is up and East is left. ESO PR Photo 25b/05 is an artist rendering of the triple system: Romulus, Sylvia, and Remus. ESO Video Clip 03/05 ESO Video Clip 03/05 Asteroid Sylvia and Her Twins [Quicktime Movie - 50 sec - 384 x 288 pix - 12.6M] Caption: ESO PR Video Clip 03/05 is an artist rendering of

FITS Liberator: Image processing software

NASA Astrophysics Data System (ADS)

Lindberg Christensen, Lars; Nielsen, Lars Holm; Nielsen, Kaspar K.; Johansen, Teis; Hurt, Robert; de Martin, David

2012-06-01

The ESA/ESO/NASA FITS Liberator makes it possible to process and edit astronomical science data in the FITS format to produce stunning images of the universe. Formerly a plugin for Adobe Photoshop, the current version of FITS Liberator is a stand-alone application and no longer requires Photoshop. This image processing software makes it possible to create color images using raw observations from a range of telescopes; the FITS Liberator continues to support the FITS and PDS formats, preferred by astronomers and planetary scientists respectively, which enables data to be processed from a wide range of telescopes and planetary probes, including ESO's Very Large Telescope, the NASA/ESA Hubble Space Telescope, NASA's Spitzer Space Telescope, ESA's XMM-Newton Telescope and Cassini-Huygens or Mars Reconnaissance Orbiter.

Adjuvant NY-ESO-1 vaccine immunotherapy in high-risk resected melanoma: a retrospective cohort analysis.

PubMed

Lattanzi, Michael; Han, Joseph; Moran, Una; Utter, Kierstin; Tchack, Jeremy; Sabado, Rachel Lubong; Berman, Russell; Shapiro, Richard; Huang, Hsin-Hui; Osman, Iman; Bhardwaj, Nina; Pavlick, Anna C

2018-05-18

Cancer-testis antigen NY-ESO-1 is a highly immunogenic melanoma antigen which has been incorporated into adjuvant vaccine clinical trials. Three such early-phase trials were conducted at our center among patients with high-risk resected melanoma. We herein report on the pooled long-term survival outcomes of these patients in comparison to historical controls. All melanoma patients treated at NYU Langone Health under any of three prospective adjuvant NY-ESO-1 vaccine trials were retrospectively pooled into a single cohort. All such patients with stage III melanoma were subsequently compared to historical control patients identified via a prospective institutional database with protocol-driven follow-up. Survival times were calculated using the Kaplan-Meier method, and Cox proportional hazard models were employed to identify significant prognostic factors and control for confounding variables. A total of 91 patients were treated with an NY-ESO-1 vaccine for the treatment of high-risk resected melanoma. Of this group, 67 patients were stage III and were selected for comparative analysis with 123 historical control patients with resected stage III melanoma who received no adjuvant therapy. Among the pooled vaccine cohort (median follow-up 61 months), the estimated median recurrence-free survival was 45 months, while the median overall survival was not yet reached. In the control cohort of 123 patients (median follow-up 30 months), the estimated median recurrence-free and overall survival were 22 and 58 months, respectively. Within the retrospective stage III cohort, NY-ESO-1 vaccine was associated with decreased risk of recurrence (HR = 0.56, p < 0.01) and death (HR = 0.51, p = 0.01). Upon controlling for sub-stage, the adjuvant NY-ESO-1 clinical trial cohort continued to exhibit decreased risk of recurrence (HR = 0.45, p < 0.01) and death (HR = 0.40, p < 0.01). In this small retrospective cohort of resected stage III melanoma

Report on the ''2017 ESO Calibration Workshop: The Second-Generation VLT Instruments and Friends''

NASA Astrophysics Data System (ADS)

Smette, A.; Kerber, F.; Kaufer, A.

2017-03-01

The participants at the 2017 ESO Calibration Workshop shared their experiences and the challenges encountered in calibrating VLT second-generation instruments and the upgraded first-generation instruments, and discussed improvements in the characterisation of the atmosphere and data reduction. A small group of ESO participants held a follow-up retreat and identified possible game changers in the future operations of the La Silla Paranal Observatory: feedback on the proposals is encouraged.

Core network infrastructure supporting the VLT at ESO Paranal in Chile

NASA Astrophysics Data System (ADS)

Reay, Harold

2000-06-01

In October 1997 a number of projects were started at ESO's Paranal Observatory at Cerro Paranal in Chile to upgrade the communications infrastructure in place at the time. The planned upgrades were to internal systems such as computer data networks and telephone installations and also data links connecting Paranal to other ESO sites. This paper details the installation work carried out on the Paranal Core Network (PCN) during the period of October 1997 to December 1999. These installations were to provide both short term solutions to the requirement for reliable high bandwidth network connectivity between Paranal and ESO HQ in Garching, Germany in time for UTI (Antu) first light and perhaps more importantly, to provide the core systems necessary for a site moving towards operational status. This paper explains the reasons for using particular cable types, network topology, and fiber backbone design and implementation. We explain why it was decided to install the PCN in two distinct stages and how equipment used in temporary installations was re-used in the Very Large Telescope networks. Finally we describe the tools used to monitor network and satellite link performance and will discuss whether network backbone bandwidth meets the expected utilization and how this bandwidth can easily be increased in the future should there be a requirement.

A Powerful Twin Arrives

NASA Astrophysics Data System (ADS)

1999-11-01

First Images from FORS2 at VLT KUEYEN on Paranal The first, major astronomical instrument to be installed at the ESO Very Large Telescope (VLT) was FORS1 ( FO cal R educer and S pectrograph) in September 1998. Immediately after being attached to the Cassegrain focus of the first 8.2-m Unit Telescope, ANTU , it produced a series of spectacular images, cf. ESO PR 14/98. Many important observations have since been made with this outstanding facility. Now FORS2 , its powerful twin, has been installed at the second VLT Unit Telescope, KUEYEN . It is the fourth major instrument at the VLT after FORS1 , ISAAC and UVES.. The FORS2 Commissioning Team that is busy installing and testing this large and complex instrument reports that "First Light" was successfully achieved already on October 29, 1999, only two days after FORS2 was first mounted at the Cassegrain focus. Since then, various observation modes have been carefully tested, including normal and high-resolution imaging, echelle and multi-object spectroscopy, as well as fast photometry with millisecond time resolution. A number of fine images were obtained during this work, some of which are made available with the present Press Release. The FORS instruments ESO PR Photo 40a/99 ESO PR Photo 40a/99 [Preview - JPEG: 400 x 345 pix - 203k] [Normal - JPEG: 800 x 689 pix - 563kb] [Full-Res - JPEG: 1280 x 1103 pix - 666kb] Caption to PR Photo 40a/99: This digital photo shows the twin instruments, FORS2 at KUEYEN (in the foreground) and FORS1 at ANTU, seen in the background through the open ventilation doors in the two telescope enclosures. Although they look alike, the two instruments have specific functions, as described in the text. FORS1 and FORS2 are the products of one of the most thorough and advanced technological studies ever made of a ground-based astronomical instrument. They have been specifically designed to investigate the faintest and most remote objects in the universe. They are "multi-mode instruments" that

Therapeutical solutions for non-malignant eso-bronchial fistulas

PubMed Central

Galie, N; Grigorie, V

2009-01-01

We assessed the efficacy of surgical treatment for the patients with eso-respiratory fistulas. The following cases revealed the anesthesic and surgical difficulties, and also intraoperative and postoperative complications that can occur when the esophageal contents get into the respiratory system. In these situations, therapy must be adapted according to fistula’s topography and etiology, and also to patients’ biological conditions. PMID:20108499

Hunting the Southern Skies with SIMBA

NASA Astrophysics Data System (ADS)

2001-08-01

First Images from the New "Millimetre Camera" on SEST at La Silla Summary A new instrument, SIMBA ("SEST IMaging Bolometer Array") , has been installed at the Swedish-ESO Submillimetre Telescope (SEST) at the ESO La Silla Observatory in July 2001. It records astronomical images at a wavelength of 1.2 mm and is able to quickly map large sky areas. In order to achieve the best possible sensitivity, SIMBA is cooled to only 0.3 deg above the absolute zero on the temperature scale. SIMBA is the first imaging millimetre instrument in the southern hemisphere . Radiation at this wavelength is mostly emitted from cold dust and ionized gas in a variety of objects in the Universe. Among other, SIMBA now opens exciting prospects for in-depth studies of the "hidden" sites of star formation , deep inside dense interstellar nebulae. While such clouds are impenetrable to optical light, they are transparent to millimetre radiation and SIMBA can therefore observe the associated phenomena, in particular the dust around nascent stars . This sophisticated instrument can also search for disks of cold dust around nearby stars in which planets are being formed or which may be left-overs of this basic process. Equally important, SIMBA may observe extremely distant galaxies in the early universe , recording them while they were still in the formation stage. Various SIMBA images have been obtained during the first tests of the new instrument. The first observations confirm the great promise for unique astronomical studies of the southern sky in the millimetre wavelength region. These results also pave the way towards the Atacama Large Millimeter Array (ALMA) , the giant, joint research project that is now under study in Europe, the USA and Japan. PR Photo 28a/01 : SIMBA image centered on the infrared source IRAS 17175-3544 PR Photo 28b/01 : SIMBA image centered on the infrared source IRAS 18434-0242 PR Photo 28c/01 : SIMBA image centered on the infrared source IRAS 17271-3439 PR Photo 28d/01

ESO adaptive optics facility progress report

NASA Astrophysics Data System (ADS)

Arsenault, Robin; Madec, Pierre-Yves; Paufique, Jerome; La Penna, Paolo; Stroebele, Stefan; Vernet, Elise; Pirard, Jean-Francois; Hackenberg, Wolfgang; Kuntschner, Harald; Jochum, Lieselotte; Kolb, Johann; Muller, Nicolas; Le Louarn, Miska; Amico, Paola; Hubin, Norbert; Lizon, Jean-Louis; Ridings, Rob; Abad, Jose A.; Fischer, Gert; Heinz, Volker; Kiekebusch, Mario; Argomedo, Javier; Conzelmann, Ralf; Tordo, Sebastien; Donaldson, Robert; Soenke, Christian; Duhoux, Philippe; Fedrigo, Enrico; Delabre, Bernard; Jost, Andreas; Duchateau, Michel; Downing, Mark; Moreno, Javier R.; Dorn, Reinhold; Manescau, Antonio; Bonaccini Calia, Domenico; Quattri, Marco; Dupuy, Christophe; Guidolin, Ivan M.; Comin, Mauro; Guzman, Ronald; Buzzoni, Bernard; Quentin, Jutta; Lewis, Steffan; Jolley, Paul; Kraus, Maximilian; Pfrommer, Thomas; Biasi, Roberto; Gallieni, Daniele; Bechet, Clementine; Stuik, Remko

2012-07-01

The ESO Adaptive Optics Facility (AOF) consists in an evolution of one of the ESO VLT unit telescopes to a laser driven adaptive telescope with a deformable mirror in its optical train. The project has completed the procurement phase and several large structures have been delivered to Garching (Germany) and are being integrated (the AO modules GRAAL and GALACSI and the ASSIST test bench). The 4LGSF Laser (TOPTICA) has undergone final design review and a pre-production unit has been built and successfully tested. The Deformable Secondary Mirror is fully integrated and system tests have started with the first science grade thin shell mirror delivered by SAGEM. The integrated modules will be tested in stand-alone mode in 2012 and upon delivery of the DSM in late 2012, the system test phase will start. A commissioning strategy has been developed and will be updated before delivery to Paranal. A substantial effort has been spent in 2011-2012 to prepare the unit telescope to receive the AOF by preparing the mechanical interfaces and upgrading the cooling and electrical network. This preparation will also simplify the final installation of the facility on the telescope. A lot of attention is given to the system calibration, how to record and correct any misalignment and control the whole facility. A plan is being developed to efficiently operate the AOF after commissioning. This includes monitoring a relevant set of atmospheric parameters for scheduling and a Laser Traffic control system to assist the operator during the night and help/support the observing block preparation.

Forty Years at ESO - Bernard Delabre and Optical Designs

NASA Astrophysics Data System (ADS)

de Zeeuw, T.; Lévêque, S.; Pasquini, L.; Péron, M.; Spyromilio, J.

2017-09-01

The optical designer Bernard Delabre has retired from ESO after 40 years at the forefront of telescope and instrument optics. A short overview of his achievements and his legacy of astronomical telescopes and instrumenta-tion is presented. Bernard Delabre was awarded the 2017 Tycho Brahe Prize by the European Astronomical Society.

NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability

PubMed Central

Sommermeyer, Daniel; Conrad, Heinke; Krönig, Holger; Gelfort, Haike; Bernhard, Helga; Uckert, Wolfgang

2013-01-01

The cancer-testis antigen NY-ESO-1 has been used as a target for different immunotherapies like vaccinations and adoptive transfer of antigen-specific cytotoxic T cells, as it is expressed in various tumor types and has limited expression in normal cells. The in vitro generation of T cells with defined antigen specificity by T cell receptor (TCR) gene transfer is an established method to create cells for immunotherapy. However, an extensive characterization of TCR which are candidates for treatment of patients is crucial for successful therapies. The TCR has to be efficiently expressed, their affinity to the desired antigen should be high enough to recognize low amounts of endogenously processed peptides on tumor cells, and the TCR should not be cross-reactive to other antigens. We characterized three NY-ESO-1 antigen-reactive cytotoxic T lymphocyte clones which were generated by different approaches of T cell priming (autologous, allogeneic), and transferred their TCR into donor T cells for more extensive evaluations. Although one TCR most efficiently bound MHC-multimers loaded with NY-ESO-1 peptide, T cells expressing this transgenic TCR were not able to recognize endogenously processed antigen. A second TCR recognized HLA-A2 independent of the bound peptide beside its much stronger recognition of NY-ESO-1 bound to HLA-A2. A third TCR displayed an intermediate but peptide-specific performance in all functional assays and, therefore, is the most promising candidate TCR for further clinical development. Our data indicate that multiple parameters of TCR gene-modified T cells have to be evaluated to identify an optimal TCR candidate for adoptive therapy. PMID:22907642

The First School for Young Astronomers Organized by ESO and the Astronomical Council of the USSR Acadeny of Sciences

NASA Astrophysics Data System (ADS)

D'Odorico, S.

1987-12-01

The first international school for young astronomers organized jointly by ESO and the Astronomical Council of the USSR Academy of Sciences took place from the 22nd to the 29th of September at the Byurakan Astrophysical Observatory of the Academy of Sciences of Armenia and was dedicated to "Observations with Large Telescopes". It was appropriately closed with a oneday visit to the Special Astrophysical Observatory at Zelenchukskaja, in northern Caucasus, home of the 6-m telescope, the largest in the world. The lecturers came from ESO and from the Soviet Union; the 45 participants were from ESO member states, from Bulgaria, Czechoslovakia, the German Democratic Republic, Poland, Spain and the USSR. After the welcome addresses by Academician V.A. Ambartsumian and by E. Ye Khachikian, Chairman of the Local Organizing Committee, the school was opened by M. Tarenghi of ESO who spoke on the characteristics of existing ESO telescopes and on the innovative features of the ESO 3.5-m New Technology Telescope, to be erected at La Silla next year. H. A. Abrahamian and J.A. Stepanian of the Byurakan Observatory presented the Byurakan 2.6-m telescope and the 1-m Schmidt respectively, illustrating the scientific programmes carried out in the recent past and presently at these two facilities.

With the VLT Interferometer towards Sharper Vision

NASA Astrophysics Data System (ADS)

2000-05-01

ESO PR Photo 14a/00 [Preview - JPEG: 359 x 400 pix - 120k] [Normal - JPEG: 717 x 800 pix - 416k] [High-Res - JPEG: 2689 x 3000 pix - 6.7M] Caption : A view of the Paranal platform with the four 8.2-m VLT Unit Telescopes (UTs) and the foundations for the 1.8-m VLT Auxiliary Telescopes (ATs) that together will be used as the VLT Interferometer (VLTI). The three ATs will move on rails (yet to be installed) between the thirty observing stations above the holes that provide access to the underlying tunnel system. The light beams from the individual telescopes will be guided towards the centrally located, partly underground Interferometry Laboratory in which the VLTI instruments will be set up. This photo was obtained in December 1999 at which time some construction materials were still present on the platform; they were electronically removed in this reproduction. The ESO VLT facility at Paranal (Chile) consists of four Unit Telescopes with 8.2-m mirrors and several 1.8-m auxiliary telescopes that move on rails, cf. PR Photo 14a/00 . While each of the large telescopes can be used individually for astronomical observations, a prime feature of the VLT is the possibility to combine all of these telescopes into the Very Large Telescope Interferometer (VLTI) . In the interferometric mode, the light beams from the VLT telescopes are brought together at a common focal point in the Interferometry Laboratory that is placed at the centre of the observing platform on top of Paranal. In principle, this can be done in such a way that the resulting (reconstructed) image appears to come from a virtual telescope with a diameter that is equal to the largest distance between two of the individual telescopes, i.e., up to about 200 metres. The theoretically achievable image sharpness of an astronomical telescope is proportional to its diameter (or, for an interferometer, the largest distance between two of its component telescopes). The interferometric observing technique will thus allow the

Into the Eye of the Helix

NASA Astrophysics Data System (ADS)

2009-02-01

A deep new image of the magnificent Helix planetary nebula has been obtained using the Wide Field Imager at ESO's La Silla Observatory. The image shows a rich background of distant galaxies, usually not seen in other images of this object. ESO PR Photo 07a/09 The Helix Nebula ESO PR Video 06a/09 Helix Nebula Zoom-in ESO PR Video 06b/09 Pan over the Helix Nebula ESO PR Video 06c/09 Zoom and pan over the Helix Nebula The Helix Nebula, NGC 7293, lies about 700 light-years away in the constellation of Aquarius (the Water Bearer). It is one of the closest and most spectacular examples of a planetary nebula. These exotic objects have nothing to do with planets, but are the final blooming of Sun-like stars before their retirement as white dwarfs. Shells of gas are blown off from a star's surface, often in intricate and beautiful patterns, and shine under the harsh ultraviolet radiation from the faint, but very hot, central star. The main ring of the Helix Nebula is about two light-years across or half the distance between the Sun and its closest stellar neighbour. Despite being photographically very spectacular the Helix is hard to see visually as its light is thinly spread over a large area of sky and the history of its discovery is rather obscure. It first appears in a list of new objects compiled by the German astronomer Karl Ludwig Harding in 1824. The name Helix comes from the rough corkscrew shape seen in the earlier photographs. Although the Helix looks very much like a doughnut, studies have shown that it possibly consists of at least two separate discs with outer rings and filaments. The brighter inner disc seems to be expanding at about 100 000 km/h and to have taken about 12 000 years to have formed. Because the Helix is relatively close -- it covers an area of the sky about a quarter of the full Moon -- it can be studied in much greater detail than most other planetary nebulae and has been found to have an unexpected and complex structure. All around the

Young Astronomers' Observe with ESO Telescopes

NASA Astrophysics Data System (ADS)

1995-11-01

Today, forty 16-18 year old students and their teachers are concluding a one-week, educational `working visit' to the ESO Headquarters in Garching (See ESO Press Release 14/95 of 8 November 1995). They are the winners of the Europe-wide contest `Europe Towards the Stars', organised by ESO with the support of the European Union, under the auspices of the Third European Week for Scientific and Technological Culture. From November 14-20, they have worked with professional ESO astronomers in order to get insight into the methods and principles of modern astronomy and astrophysics, as carried out at one of the world's foremost international centres. This included very successful remote observations with the ESO 3.5-m New Technology Telescope (NTT) and the 1.4-m Coude Auxiliary Telescope (CAT) via a satellite link between the ESO Headquarters and the La Silla observatory in Chile, 12,000 kilometres away. After a general introduction to modern astronomy on the first day of the visit, the participants divided into six teams, according to their interests. Some chose to observe distant galaxies, others prefered to have a closer look on binary stars, and one team decided to investigate a star which is thought to be surrounded by a proto-planetary system. Each team was supported by an experienced ESO astronomer. Then followed the observations at the remote consoles during three nights, the first at the NTT and the following at the CAT. Each team had access to the telescope during half a night. Although the work schedule - exactly as in `real' science - was quite hard, especially during the following data reduction and interpretative phase, all teams managed extremely well and in high spirits. The young astronomers' observations were favoured by excellent atmospheric conditions. At the NTT, the seeing was better than 0.5 arcsecond during several hours, an exceptional value that allows very good images to be obtained. All observations represent solid and interesting science, and

TNO Photometry and Spectroscopy at ESO and Calar Alto

NASA Astrophysics Data System (ADS)

Boehnhardt, H.; Sekiguchi, T.; Vair, M.; Hainaut, O.; Delahodde, C.; West, R. M.; Tozzi, G. P.; Barrera, L.; Birkle, K.; Watanabe, J.; Meech, K.

New photometry and spectroscopy of Transneptunian objects (TNO) has been obtained at ESO (VLT+FORS1, NTT+SOFI) and the Calar Alto (3.5m+MOSCA) observatory. BVRI photometry of more than 10 objects confirms the general colour-colour distribution of TNOs found previously. Quasi-simultaneous spectroscopy in the visible wavelength range of 5 TNOs did not reveal any spectral signature apart from the spetral gradients which are in agreement with the broadband colours. JHK filter photometry of 3 objects indicates that the reddening may only occur in the near-IR at least in some cases. Using new observations from the ESO VLT the lightcurve, colours and spectrum of 1996TO66 are investigated: the rotation period of 6.25h is confirmed, also the change in the lightcurve between 1997 and 1998 which indicates an exceptional behaviour in this object (temporary cometary activity ?). The 1999 photometry and spectroscopy in the visible revealed solar colours, no reddening and no spectral features. V-R colour changes over the rotation phase are not found. This works is done in colaboration with:

First Results from the UT1 Science Verification Programme

NASA Astrophysics Data System (ADS)

1998-11-01

of galaxies, galaxy clusters, and large scale structure. Others will concentrate on more nearby objects, including stars and nebulae in the Milky Way galaxy, and some will attempt to study our own solar system. The following six research programmes were presented at the Press Conference that took place at the ESO Headquarters in Garching (Germany) today. Deep Galaxy Counts and Photometric Redshifts in the HDF-S NIC3 Field The goal of this programme was to verify the capability of the VLT by obtaining the deepest possible ground-based images and using multicolour information to derive the redshifts (and hence the distances) of the faintest galaxies. The space distribution, luminosity and colour of these extreme objects may provide crucial information on the initial phases of the evolution of the universe. The method is known as photometric redshift determination . The VLT Test Camera was used to collect CCD images for a total of 16.6 hours in five spectral filters (U, B, V, R and I) in the so-called HDF-S NIC3 field. This is a small area (about 1 arcmin square) of the southern sky where very deep observations in the infrared bands J, H and K (1.1, 1.6 and 2.2µm, respectively) have been obtained by the Hubble Space Telescope (HST). The observations were combined and analyzed by a team of astronomers at ESO and the Observatory of Rome (Italy). Galaxies were detected in the field down to magnitude ~ 27-28. In most colours, the planned limiting values of the fluxes were successfully reached. ESO PR Photo 48a/98 ESO PR Photo 48a/98 [Preview - JPEG: 800 x 856 pix - 144k] [High-Res - JPEG: 3000 x 3210 pix - 728k] PR Photo 48a/98 shows some examples of photometric redshift determination for faint galaxies in the HDF-S NIC3 field. The filled points are the fluxes measured in the five colors observed with the VLT Test Camera (U, B, V, R and I) and in the infrared H spectral band with the NICMOS instrument on the Hubble Space Telescope. The curves constitute the best fit to the

Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens.

PubMed

Hayes, Stephen J; Hng, Keng Ngee; Clark, Peter; Thistlethwaite, Fiona; Hawkins, Robert E; Ang, Yeng

2014-04-14

To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclature of human and veterinary medicine coding system. Original haematoxylin and eosin stained sections were reviewed, using light microscopy, to confirm classification and tumour differentiation. A total of 27 adenocarcinoma resection specimens were then assessed using immunohistochemistry for NY-ESO-1 expression: 4 well differentiated, 14 moderately differentiated, 4 moderate-poorly differentiated, and 5 poorly differentiated. Four out of a total of 27 cases of esophageal adenocarcinoma examined (15%) displayed diffuse cytoplasmic and nuclear expression for NY-ESO-1. They displayed a heterogeneous and mosaic-type pattern of diffuse staining. Diffuse cytoplasmic staining was not identified in any of these structures: stroma, normal squamous epithelium, normal submucosal gland and duct, Barrett's esophagus (goblet cell), Barrett's esophagus (non-goblet cell) and high grade glandular dysplasia. All adenocarcinomas showed an unexpected dot-type pattern of staining at nuclear, paranuclear and cytoplasmic locations. Similar dot-type staining, with varying frequency and size of dots, was observed on examination of Barrett's metaplasia, esophageal submucosal gland acini and the large bowel negative control, predominantly at the crypt base. Furthermore, a prominent pattern of apical (luminal) cytoplasmic dot-type staining was observed in some cases of Barrett's metaplasia and also adenocarcinoma. A further morphological finding of interest was noted on examination of haematoxylin and eosin stained sections, as aggregates of lymphocytes were consistently noted to surround submucosal glands. We have demonstrated for the first time NY-ESO-1 expression by esophageal

Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens

PubMed Central

Hayes, Stephen J; Hng, Keng Ngee; Clark, Peter; Thistlethwaite, Fiona; Hawkins, Robert E; Ang, Yeng

2014-01-01

AIM: To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS: A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclature of human and veterinary medicine coding system. Original haematoxylin and eosin stained sections were reviewed, using light microscopy, to confirm classification and tumour differentiation. A total of 27 adenocarcinoma resection specimens were then assessed using immunohistochemistry for NY-ESO-1 expression: 4 well differentiated, 14 moderately differentiated, 4 moderate-poorly differentiated, and 5 poorly differentiated. RESULTS: Four out of a total of 27 cases of esophageal adenocarcinoma examined (15%) displayed diffuse cytoplasmic and nuclear expression for NY-ESO-1. They displayed a heterogeneous and mosaic-type pattern of diffuse staining. Diffuse cytoplasmic staining was not identified in any of these structures: stroma, normal squamous epithelium, normal submucosal gland and duct, Barrett’s esophagus (goblet cell), Barrett’s esophagus (non-goblet cell) and high grade glandular dysplasia. All adenocarcinomas showed an unexpected dot-type pattern of staining at nuclear, paranuclear and cytoplasmic locations. Similar dot-type staining, with varying frequency and size of dots, was observed on examination of Barrett’s metaplasia, esophageal submucosal gland acini and the large bowel negative control, predominantly at the crypt base. Furthermore, a prominent pattern of apical (luminal) cytoplasmic dot-type staining was observed in some cases of Barrett’s metaplasia and also adenocarcinoma. A further morphological finding of interest was noted on examination of haematoxylin and eosin stained sections, as aggregates of lymphocytes were consistently noted to surround submucosal glands. CONCLUSION: We have demonstrated for the first time NY-ESO

Of Rings and Volcanoes

NASA Astrophysics Data System (ADS)

2002-01-01

Fine Images of Saturn and Io with VLT NAOS-CONICA Summary With its new NAOS-CONICA Adaptive Optics facility, the ESO Very Large Telescope (VLT) at the Paranal Observatory has recently obtained impressive views of the giant planet Saturn and Io, the volcanic moon of Jupiter. They show the two objects with great clarity, unprecedented for a ground-based telescope. The photos were made during the ongoing commissioning of this major VLT instrument, while it is being optimized and prepared for regular observations that will start later this year. PR Photo 04a/02 : VLT NAOS-CONICA photo of the giant planet Saturn (composite H+K band image). PR Photo 04b/02 : The Jovian moon Io (Br-gamma image). PR Photo 04c/02 : The Jovian moon Io (composite Br-gamma + L' image). Commissioning of NAOS-CONICA progresses "First light" for the new NAOS-CONICA Adaptive Optics facility on the 8.2-m VLT YEPUN telescope at the Paranal Observatory was achieved in November 2001, cf. ESO PR 25/01. A second phase of the "commissioning" of the new facility began on January 22, 2002, now involving specialized observing modes and with the aim of trimming it to maximum performance before it is made available to the astronomers later this year. During this demanding and delicate work, more test images have been made of various astronomical objects [1]. Some of these show selected solar system bodies, for which the excellent image sharpness achievable with this new instrument is of special significance. In fact, the VLT photos of the giant planet Saturn and Io, the innermost of Jupiter's four large moons, are among the sharpest ever obtained from the ground . They even compare well with some photos obtained from space, as can be seen via the related weblinks indicated below. The raw NAOS-CONICA data from which these images shown in this Photo Release were produced are now available via the public VLT Science Archive Facility [2]. The NAOS adaptive optics corrector was built, under an ESO contract, by the

Measurement of serum antibodies against NY-ESO-1 by ELISA: A guide for the treatment of specific immunotherapy for patients with advanced colorectal cancer.

PubMed

Long, Yan-Yan; Wang, Yu; Huang, Qian-Rong; Zheng, Guang-Shun; Jiao, Shun-Chang

2014-10-01

NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-based specific-immunotherapy for these patients. Furthermore, the present study was the first to evaluate the kinetic expression of anti-NY-ESO-1 Abs and investigate the possible influencing factors. A total of 239 serum samples from 155 pathologically confirmed patients with advanced CRC (stages III and IV) were collected. The presence of spontaneous Abs against NY-ESO-1 was analyzed using an enzyme-linked immunosorbent assay (ELISA). The results demonstrated that 24.5% (38/155) of the investigated patients were positive for NY-ESO-1-specific Abs. No statistically significant correlations were identified between the expression of anti-NY-ESO-1 Abs and clinicopathological parameters, including age and gender, location, grading, local infiltration, lymph node status, metastatic status and K-ras mutation status (P>0.05). In 59 patients, the kinetic expression of anti-NY-ESO-1 Abs was analyzed, of which 14 patients were initially positive and 45 patients were initially negative. Notably, 16/59 (27.1%) patients changed their expression status during the study period, and the initially positive patients were more likely to change compared with the initially negative patients (85.7 vs. 8.8%; P<0.001). Therefore, monitoring serum Abs against NY-ESO-1 by ELISA is an easy and feasible method. The high expression rate of NY-ESO-1-specific Abs in CRC patients indicates that measuring the levels of serum Abs against NY-ESO-1 may guide the treatment of NY-ESO-1-based specific immunotherapy for patients with advanced CRC.

Measurement of serum antibodies against NY-ESO-1 by ELISA: A guide for the treatment of specific immunotherapy for patients with advanced colorectal cancer

PubMed Central

LONG, YAN-YAN; WANG, YU; HUANG, QIAN-RONG; ZHENG, GUANG-SHUN; JIAO, SHUN-CHANG

2014-01-01

NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-based specific-immunotherapy for these patients. Furthermore, the present study was the first to evaluate the kinetic expression of anti-NY-ESO-1 Abs and investigate the possible influencing factors. A total of 239 serum samples from 155 pathologically confirmed patients with advanced CRC (stages III and IV) were collected. The presence of spontaneous Abs against NY-ESO-1 was analyzed using an enzyme-linked immunosorbent assay (ELISA). The results demonstrated that 24.5% (38/155) of the investigated patients were positive for NY-ESO-1-specific Abs. No statistically significant correlations were identified between the expression of anti-NY-ESO-1 Abs and clinicopathological parameters, including age and gender, location, grading, local infiltration, lymph node status, metastatic status and K-ras mutation status (P>0.05). In 59 patients, the kinetic expression of anti-NY-ESO-1 Abs was analyzed, of which 14 patients were initially positive and 45 patients were initially negative. Notably, 16/59 (27.1%) patients changed their expression status during the study period, and the initially positive patients were more likely to change compared with the initially negative patients (85.7 vs. 8.8%; P<0.001). Therefore, monitoring serum Abs against NY-ESO-1 by ELISA is an easy and feasible method. The high expression rate of NY-ESO-1-specific Abs in CRC patients indicates that measuring the levels of serum Abs against NY-ESO-1 may guide the treatment of NY-ESO-1-based specific immunotherapy for patients with advanced CRC. PMID:25187840

ESO089-G018 and ESO089-G019: long-slit spectroscopy of emission-line galaxies

NASA Astrophysics Data System (ADS)

da Rocha-Poppe, P. C.; Faúndez-Abans, M.; Fernandes-Martin, V. A.; Fernandes, I. F.; de Oliveira-Abans, M.; Rodrígues-Ardila, A.

2010-03-01

We present the first spectroscopic observations for the galaxies ESO089-G018 (hereafter G18, an Sb(?)-type galaxy seen nearly edge-on) and ESO089-G019 (hereafter G19, an SA(s): a peculiar galaxy), extracted from the sample of ring-shaped galaxies compiled in Faúndez-Abans & de Oliveira-Abans. The main goal of this work is to investigate the spectral classification using the three line-ratio diagrams, called diagnostic diagrams, of Veilleux & Osterbrock. However, in order to separate the different types of galaxies [HII galaxies, Seyfert 2 galaxies and low-ionization nuclear emission-line region galaxies (LINERs)] we have to used empirical boundaries between them. Based on the observed spectra, we suggest G18 is a `weak-[OI] LINER' or even a `transition object' or LINER/HII. In the case of G19, we see Hβ in absorption and no [OIII] lines, impeding the [OIII]/Hβ ratio to be estimated. However, other lines ratios have been evaluated for the discussion. We classify the nature of G19 as ambiguous, because of the difficulty in determining its ionizing source (narrow-line active galactic nuclei or HII galaxies) in different diagnostic diagrams. The errors in the fluxes were mostly caused by uncertainties in the placement of the continuum level. We have estimated nuclear redshift of z = 0.034 (G18) and z = 0.039 (G19), corresponding to a heliocentric velocity of 10246 and 11734kms-1, respectively. Some other physical parameters have been derived whenever possible. All spectra were reduced and analysed in a homogeneous way with the standard IRAF procedures. Based on observations carried out at Observatório do Pico dos Dias (OPD), which operated by the LNA/MCT, Brazil-MG. E-mail: paulopoppe@gmail.com

Shadow of a Large Disc Casts New Light on the Formation of High Mass Stars

NASA Astrophysics Data System (ADS)

2004-05-01

hydrogen gas and create a so-called H II region. The total luminosity of these stars exceeds that of our Sun by almost a factor of ten million. Adjacent to the south-western edge of the H II region, there is a huge cloud of molecular gas which is believed to be a site of ongoing star formation. In order to search for newly forming high-mass stars, Rolf Chini of the Ruhr-Universität Bochum (Germany) and his collaborators have recently investigated the interface between the H II region and the molecular cloud by means of very deep optical and infrared imaging between 0.4 and 2.2 µm. This was done with ISAAC (at 1.25, 1.65 and 2.2 µm) at the ESO Very Large Telescope (VLT) on Cerro Paranal in September 2002 and with EMMI (at 0.45, 0.55, 0.8 µm) at the ESO New Technology Telescope (NTT), La Silla, in July 2003. The image quality was limited by atmospheric turbulence and varied between 0.4 and 0.8 arcsec. The result of these efforts is shown in PR Photo 15a/04. Rolf Chini is pleased: "Our measurements are so sensitive that the south-western molecular cloud of M 17 is penetrated and the faint nebular emission of the H II region, which is partly located behind the molecular cloud, could be detected through the dust." Against the nebular background of the H II region a large opaque silhouette is seen associated with an hourglass shaped reflection nebula. The silhouette disc ESO PR Photo 15b/04 ESO PR Photo 15b/04 [Preview - JPEG: 400 x 475 pix - 348k] [Normal - JPEG: 800 x 950 pix - 907k] Caption: PR Photo 15b/04 shows a Ks-band image of the silhouette disc obtained with the NACO Adaptive Optics camera at the 8.2-m VLT YEPUN telescope at Paranal. The displayed field-of-view is outlined in PR Photo 15a/04. White contours delineate the densest part of the disc (inner torus). The visible stars (slightly elongated due to the adaptive optics technique) are embedded within the molecular cloud but are probably unrelated to the disc. The insert shows a deconvolved zoomed version of the

The AMBRE project: Parameterisation of FGK-type stars from the ESO:HARPS archived spectra

NASA Astrophysics Data System (ADS)

De Pascale, M.; Worley, C. C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Bijaoui, A.

2014-10-01

Context. The AMBRE project is a collaboration between the European Southern Observatory (ESO) and the Observatoire de la Côte d'Azur (OCA). It has been established to determine the stellar atmospheric parameters of the archived spectra of four ESO spectrographs. Aims: The analysis of the ESO:HARPS archived spectra for the determination of their atmospheric parameters (effective temperature, surface gravity, global metallicities, and abundance of α-elements over iron) is presented. The sample being analysed (AMBRE:HARPS) covers the period from 2003 to 2010 and is comprised of 126 688 scientific spectra corresponding to ~17 218 different stars. Methods: For the analysis of the AMBRE:HARPS spectral sample, the automated pipeline developed for the analysis of the AMBRE:FEROS archived spectra has been adapted to the characteristics of the HARPS spectra. Within the pipeline, the stellar parameters are determined by the MATISSE algorithm, which has been developed at OCA for the analysis of large samples of stellar spectra in the framework of galactic archaeology. In the present application, MATISSE uses the AMBRE grid of synthetic spectra, which covers FGKM-type stars for a range of gravities and metallicities. Results: We first determined the radial velocity and its associated error for the ~15% of the AMBRE:HARPS spectra, for which this velocity had not been derived by the ESO:HARPS reduction pipeline. The stellar atmospheric parameters and the associated chemical index [α/Fe] with their associated errors have then been estimated for all the spectra of the AMBRE:HARPS archived sample. Based on key quality criteria, we accepted and delivered the parameterisation of 93 116 (74% of the total sample) spectra to ESO. These spectra correspond to ~10 706 stars; each are observed between one and several hundred times. This automatic parameterisation of the AMBRE:HARPS spectra shows that the large majority of these stars are cool main-sequence dwarfs with metallicities

More Saturnian Moons

NASA Astrophysics Data System (ADS)

2000-10-01

Saturn takes the lead Following the discovery of at least four additional moons of that planet, Saturn has again taken the lead as the planet with the greatest number of known natural satellites. A corresponding announcement was made today by an international team of astronomers [1] at a meeting of the Division for Planetary Sciences (DPS) of the American Astronomical Society (AAS) in Pasadena (California, USA). The four new faint bodies were spotted during observations in August-September 2000 at several astronomical telescopes around the world. Subsequent orbital calculations have indicated that these objects are almost certainly new satellites of the giant planet. Two Saturnian moons found at La Silla ESO PR Photo 29a/00 ESO PR Photo 29a/00 [Preview - JPEG: 263 x 400 pix - 26k] [Normal - JPEG: 525 x 800 pix - 93k] ESO PR Photo 29b/00 ESO PR Photo 29b/00 [Preview - JPG: 289 x 400 pix - 43k] [Normal - JPG: 578 x 800 pix - 432k] ESO PR Photo 29c/00 ESO PR Photo 29c/00 [Animated GIF: 330 x 400 pix - 208k] Captions : The photos show the discovery images of two new Saturnian moons, as registered on August 7, 2000, with the Wide-Field Imager (WFI) camera at the MPG/ESO 2.2-m telescope at the La Silla Observatory. Photo PR 29a/00 displays the faint image of the newly discovered moon S/2000 S 1 in the lower right corner of the field. A spiral galaxy is seen in the upper left corner of this photo. The other objects are (background) stars in the Milky Way. Photo PR 29b/00 is a combination of three successive WFI exposures of the second moon, S/2000 S 2 . Because of its motion, there are three images (to the left). Photo PR 29c/00 is an animated GIF image of the same three exposures that demonstrates this motion. Technical details are found below. The observations of the first two objects are described on a Circular of the International Astronomical Union (IAU) that was issued today [2]. The images of these new moons were first registered on exposures made on August 7, 2000

NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers.

PubMed

Oshima, Yoko; Shimada, Hideaki; Yajima, Satoshi; Nanami, Tatsuki; Matsushita, Kazuyuki; Nomura, Fumio; Kainuma, Osamu; Takiguchi, Nobuhiro; Soda, Hiroaki; Ueda, Takeshi; Iizasa, Toshihiko; Yamamoto, Naoto; Yamamoto, Hiroshi; Nagata, Matsuo; Yokoi, Sana; Tagawa, Masatoshi; Ohtsuka, Seiko; Kuwajima, Akiko; Murakami, Akihiro; Kaneko, Hironori

2016-01-01

Although serum NY-ESO-1 antibodies (s-NY-ESO-1-Abs) have been reported in patients with esophageal carcinoma, this assay system has not been used to study a large series of patients with various other cancers. Serum samples of 1969 cancer patients [esophageal cancer (n = 172), lung cancer (n = 269), hepatocellular carcinoma (n = 91), prostate cancer (n = 358), gastric cancer (n = 313), colorectal cancer (n = 262), breast cancer (n = 365)] and 74 healthy individuals were analyzed using an originally developed enzyme-linked immunosorbent assay system for s-NY-ESO-1-Abs. The optical density cut-off value, determined as the mean plus three standard deviations for serum samples from the healthy controls, was fixed at 0.165. Conventional tumor markers were also evaluated in patients with esophageal carcinoma. The positive rate of s-NY-ESO-1-Abs in patients with esophageal cancer (31 %) was significantly higher than that in the other groups: patients with lung cancer (13 %), patients with hepatocellular carcinoma (11 %), patients with prostate cancer (10 %), patients with gastric cancer (10 %), patients with colorectal cancer (8 %), patients with breast cancer (7 %), and healthy controls (0 %). The positive rate of s-NY-ESO-1-Abs was comparable to that of serum p53 antibodies (33 %), squamous cell carcinoma antigen (36 %), carcinoembryonic antigen (26 %), and CYFRA 21-1 (18 %) and gradually increased with the tumor stage. The positive rate of s-NY-ESO-1-Abs was significantly higher in patients with esophageal cancer than in patients with the other types of cancers. On the basis of its high specificity and sensitivity, even in patients with stage I tumors, s-NY-ESO-1-Abs may be one of the first choices for esophageal cancer.

Science with ESO's Multi-conjugate Adaptive-optics Demonstrator - MAD

NASA Astrophysics Data System (ADS)

Melnick, Jorge; Marchetti, Enrico; Amico, Paola

2012-07-01

ESO's Multi-conjugate Adaptive-optics Demonstrator (MAD) was a prototype designed and built to demonstrate wide-field adaptive optics science on large telescopes. The outstanding results obtained during commissioning and guaranteed time observations (GTO) prompted ESO to issue and open call to the community for 23 science demonstration (SD) observing nights distributed in three runs (in order to provide access to the summer an winter skies). Thus, in total MAD was used for science for 33 nights including the 10 nights of GTO time. date, 19 articles in refereed journals (including one in Nature) have been published based fully or partially o MAD data. To the best of our knowledge, these are not only the first, but also the only scientific publication from MCAO instruments world-wide to date (at least in Astronomy). The scientific impact of these publication, as measured by the h-index, is comparable to that of other AO instruments on the VLT, although over the years these instruments have been allocated many more nights than MAD. In this contribution we present an overview of the scientific results from MAD and a more detailed discussion of the most cited papers.

The Gaia-ESO Survey Astrophysical Calibration

NASA Astrophysics Data System (ADS)

Pancino, E.; Gaia-ESO Survey Consortium

2016-05-01

The Gaia-ESO Survey is a wide field spectroscopic survey recently started with the FLAMES@VLT in Cerro Paranal, Chile. It will produce radial velocities more accurate than Gaia's for faint stars (down to V ≃ 18), and astrophysical parameters and abundances for approximately 100 000 stars, belonging to all Galactic populations. 300 nights were assigned in 5 years (with the last year subject to approval after a detailed report). In particular, to connect with other ongoing and planned spectroscopic surveys, a detailed calibration program — for the astrophysical parameters derivation — is planned, including well known clusters, Gaia benchmark stars, and special equatorial calibration fields designed for wide field/multifiber spectrographs.

Explosions in Majestic Spiral Beauties

NASA Astrophysics Data System (ADS)

2004-12-01

North of the galaxy's centre, near the periphery (see PR Photo 33b/04): it is Supernova 2004dk that was first reported on August 1, 2004. Observations a few days later showed this to be a supernova of Type Ib or Ic [3], caught a few days before maximum light. This particular kind of supernova is believed to result from the demise of a massive star that has somehow lost its entire hydrogen envelope, probably as a result of mass transfer in a binary system, before exploding. Also visible on the image is the trail left by a satellite, which passed by during one of the exposures taken in the B filter, hence its blue colour. This is an illustration that even in such a remote place as the Paranal Observatory in the Atacama desert, astronomers are not completely sheltered from light pollution. ESO PR Photo 33c/04 ESO PR Photo 33c/04 NGC 7424 - VIMOS+VLT Colour composite [Preview - JPEG: 400 x 514 pix - 110k] [Normal - JPEG: 800 x 1028 pix - 995k] [FullRes - JPEG: 1887 x 2424 pix - 5.4M] Caption: ESO PR Photo 33c/04 shows a composite colour-coded image of another magnificent spiral galaxy, NGC 7424, at a distance of 40 million light-years. It is based on images obtained with the multi-mode VIMOS instrument on the ESO Very Large Telescope (VLT) in three different wavelength bands (see Technical information below). The image covers 6.5 x 7.2 arcmin on the sky. North is up and East is to the right. The second galaxy imaged by the VLT (ESO PR Photo 33c/04) is another spiral, the beautiful multi-armed NGC 7424 that is seen almost directly face-on. Located at a distance of roughly 40 million light-years in the constellation Grus (the Crane), this galaxy was discovered by Sir John Herschel while observing at the Cape of Good Hope. This other example of a "grand design" galaxy is classified as "SAB(rs)cd" [2], meaning that it is intermediate between normal spirals (SA) and strongly barred galaxies (SB) and that it has rather open arms with a small central region. It also shows many

The Blob, the Very Rare Massive Star and the Two Populations

NASA Astrophysics Data System (ADS)

2005-04-01

The nebula N214 [1] is a large region of gas and dust located in a remote part of our neighbouring galaxy, the Large Magellanic Cloud. N214 is a quite remarkable site where massive stars are forming. In particular, its main component, N214C (also named NGC 2103 or DEM 293), is of special interest since it hosts a very rare massive star, known as Sk-71 51 [2] and belonging to a peculiar class with only a dozen known members in the whole sky. N214C thus provides an excellent opportunity for studying the formation site of such stars. Using ESO's 3.5-m New Technology telescope (NTT) located at La Silla (Chile) and the SuSI2 and EMMI instruments, astronomers from France and the USA [3] studied in great depth this unusual region by taking the highest resolution images so far as well as a series of spectra of the most prominent objects present. N214C is a complex of ionised hot gas, a so-called H II region [4], spreading over 170 by 125 light-years (see ESO PR Photo 12b/05). At the centre of the nebula lies Sk-71 51, the region's brightest and hottest star. At a distance of ~12 light-years north of Sk-71 51 runs a long arc of highly compressed gas created by the strong stellar wind of the star. There are a dozen less bright stars scattered across the nebula and mainly around Sk-71 51. Moreover, several fine, filamentary structures and fine pillars are visible. The green colour in the composite image, which covers the bulk of the N214C region, comes from doubly ionised oxygen atoms [5] and indicates that the nebula must be extremely hot over a very large extent. The Star Sk-71 51 decomposed ESO PR Photo 12c/05 ESO PR Photo 12c/05 The Cluster Around Sk-71 51 [Preview - JPEG: 400 x 620 pix - 189k] [Normal - JPEG: 800 x 1239 pix - 528k] Caption: ESO PR Photo 12c/05 shows a small field around the hot star Sk-71 51 as seen through the V filter. The left image shows a single frame after subtraction of the nebular background. The image quality - or seeing - is roughly 8.5 pixels

The MATISSE analysis of large spectral datasets from the ESO Archive

NASA Astrophysics Data System (ADS)

Worley, C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Vernisse, Y.; Ordenovic, C.; Bijaoui, A.

2010-12-01

The automated stellar classification algorithm, MATISSE, has been developed at the Observatoire de la Côte d'Azur (OCA) in order to determine stellar temperatures, gravities and chemical abundances for large datasets of stellar spectra. The Gaia Data Processing and Analysis Consortium (DPAC) has selected MATISSE as one of the key programmes to be used in the analysis of the Gaia Radial Velocity Spectrometer (RVS) spectra. MATISSE is currently being used to analyse large datasets of spectra from the ESO archive with the primary goal of producing advanced data products to be made available in the ESO database via the Virtual Observatory. This is also an invaluable opportunity to identify and address issues that can be encountered with the analysis large samples of real spectra prior to the launch of Gaia in 2012. The analysis of the archived spectra of the FEROS spectrograph is currently underway and preliminary results are presented.

Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells

PubMed Central

Mobergslien, Anne; Vasovic, Vlada; Mathiesen, Geir; Fredriksen, Lasse; Westby, Phuong; Eijsink, Vincent GH; Peng, Qian; Sioud, Mouldy

2015-01-01

Given their safe use in humans and inherent adjuvanticity, Lactic Acid Bacteria may offer several advantages over other mucosal delivery strategies for cancer vaccines. The objective of this study is to evaluate the immune responses in mice after oral immunization with Lactobacillus (L) plantarum WCFS1 expressing a cell-wall anchored tumor antigen NY-ESO-1. And to investigate the immunostimulatory potency of this new candidate vaccine on human dendritic cells (DCs). L. plantarum displaying NY-ESO-1 induced NY-ESO-1 specific antibodies and T-cell responses in mice. By contrast, L. plantarum displaying conserved proteins such as heat shock protein-27 and galectin-1, did not induce immunity, suggesting that immune tolerance to self-proteins cannot be broken by oral administration of L. plantarum. With respect to immunomodulation, immature DCs incubated with wild type or L. plantarum-NY-ESO-1 upregulated the expression of co-stimulatory molecules and secreted a large amount of interleukin (IL)-12, TNF-α, but not IL-4. Moreover, they upregulated the expression of immunosuppressive factors such as IL-10 and indoleamine 2,3-dioxygenase. Although L. plantarum-matured DCs expressed inhibitory molecules, they stimulated allogeneic T cells in-vitro. Collectively, the data indicate that L. plantarum-NY-ESO-1 can evoke antigen-specific immunity upon oral administration and induce DC maturation, raising the potential of its use in cancer immunotherapies. PMID:26185907

Comprehensive adipocytic and neurogenic tissue microarray analysis of NY-ESO-1 expression - a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma

PubMed Central

Shurell, Elizabeth; Vergara-Lluri, Maria E.; Li, Yunfeng; Crompton, Joseph G.; Singh, Arun; Bernthal, Nicholas; Wu, Hong; Eilber, Fritz C.; Dry, Sarah M.

2016-01-01

Background Immunotherapy targeting cancer-testis antigen NY-ESO-1 shows promise for tumors with poor response to chemoradiation. Malignant peripheral nerve sheath tumors (MPNSTs) and liposarcomas (LPS) are chemoresistant and have few effective treatment options. Materials Methods Using a comprehensive tissue microarray (TMA) of both benign and malignant tumors in primary, recurrent, and metastatic samples, we examined NY-ESO-1 expression in peripheral nerve sheath tumor (PNST) and adipocytic tumors. The PNST TMA included 42 MPNSTs (spontaneous n = 26, NF1-associated n = 16), 35 neurofibromas (spontaneous n = 22, NF-1 associated n = 13), 11 schwannomas, and 18 normal nerves. The LPS TMA included 48 well-differentiated/dedifferentiated (WD/DD) LPS, 13 myxoid/round cell LPS, 3 pleomorphic LPS, 8 lipomas, 1 myelolipoma, and 3 normal adipocytic tissue samples. Stained in triplicate, NY-ESO-1 intensity and density were scored. Results NY-ESO-1 expression was exclusive to malignant tumors. 100% of myxoid/round cell LPS demonstrated NY-ESO-1 expression, while only 6% of WD/DD LPS showed protein expression, one of which was WD LPS. Of MPNST, 4/26 (15%) spontaneous and 2/16 (12%) NF1-associated MPNSTs demonstrated NY-ESO-1 expression. Strong NY-ESO-1 expression was observed in myxoid/round cell and dedifferentiated LPS, and MPNST in primary, neoadjuvant, and metastatic settings. Conclusions We found higher prevalence of NY-ESO-1 expression in MPNSTs than previously reported, highlighting a subset of MPNST patients who may benefit from immunotherapy. This study expands our understanding of NY-ESO-1 in WD/DD LPS and is the first demonstration of staining in a WD LPS and metastatic/recurrent myxoid/round cell LPS. These results suggest immunotherapy targeting NY-ESO-1 may benefit patients with aggressive tumors resistant to conventional therapy. PMID:27655679

Resolving Planet Formation in the Era of ALMA and Extreme AO Report on the joint ESO/NRAO Conference

NASA Astrophysics Data System (ADS)

Dent, W. R. F.; Hales, A.; Milli, J.

2016-12-01

ALMA in its long-baseline configuration, as well as new optical/near-infrared adaptive optics instruments such as SPHERE and GPI, are now able to achieve spatial resolutions considerably better than 0.1 arcseconds. These facilities are enabling us to observe for the first time the regions around young stars where planets form. Already, complex structures including holes, spiral waves and extreme asymmetries are being found in these protoplanetary discs. To discuss these newly-imaged phenomena, and to enable cross-fertilisation of ideas between the two wavelength ranges, a joint ESO/NRAO workshop was held in Santiago. We present here a summary and some highlights of the meeting.

Two Galaxies for a Unique Event

NASA Astrophysics Data System (ADS)

2009-04-01

To celebrate the 100 Hours of Astronomy, ESO is sharing two stunning images of unusual galaxies, both belonging to the Sculptor group of galaxies. The images, obtained at two of ESO's observatories at La Silla and Paranal in Chile, illustrate the beauty of astronomy. ESO PR Photo 14a/09 Irregular Galaxy NGC 55 ESO PR Photo 14b/09 Spiral Galaxy NGC 7793 As part of the International Year of Astronomy 2009 Cornerstone project, 100 Hours of Astronomy, the ambitious "Around the World in 80 Telescopes" event is a unique live webcast over 24 hours, following night and day around the globe to some of the most advanced observatories on and off the planet. To provide a long-lasting memory of this amazing world tour, observatories worldwide are revealing wonderful, and previously unseen, astronomical images. For its part, ESO is releasing outstanding pictures of two galaxies, observed with telescopes at the La Silla and Paranal observatories. The first of these depicts the irregular galaxy NGC 55, a member of the prominent Sculptor group of galaxies in the southern constellation of Sculptor. The galaxy is about 70 000 light-years across, that is, a little bit smaller than our own Milky Way. NGC 55 actually resembles more our galactic neighbour, the Large Magellanic Cloud (LMC), although the LMC is seen face-on, whilst NGC 55 is edge-on. By studying about 20 planetary nebulae in this image, a team of astronomers found that NGC 55 is located about 7.5 million light-years away. They also found that the galaxy might be forming a bound pair with the gorgeous spiral galaxy NGC 300 . Planetary nebulae are the final blooming of Sun-like stars before their retirement as white dwarfs. This striking image of NGC 55, obtained with the Wide Field Imager on the 2.2-metre MPG/ESO telescope at La Silla, is dusted with a flurry of reddish nebulae, created by young, hot massive stars. Some of the more extended ones are not unlike those seen in the LMC, such as the Tarantula Nebula. The quality

N° 15-2000: ESA, CERN and ESO launch "Physics on Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

But how much do the citizens of Europe really know about physics? Here is a unique opportunity to learn more about this elusive subject! Beginning in February 2000, three major European research establishments [1] are organising a unique Europe-wide programme to raise the public awareness of physics and related sciences. "Physics on Stage" is launched by the European Space Agency (ESA), the European Laboratory for Particle Physics (CERN), and the European Southern Observatory (ESO), with support from the European Union (EU). Other partners include the European Physical Society (EPS) and the European Association for Astronomy Education (EAAE). This exciting programme is part of the European Week for Science and Technology and will culminate in a Science Festival during November 6-11, 2000, at CERN, Geneva. Why "Physics on Stage"? The primary goal of "Physics on Stage" is to counteract the current decline in interest and knowledge of physics among Europe's citizens by means of a series of highly visible promotional activities. It will bring together leading scientists and educators, government bodies and the media, to confront the diminishing attraction of physics to young people and to develop strategies to reverse this trend. The objective in the short term is to infuse excitement and to provide new educational materials. In the longer term, "Physics on Stage" will generate new developments by enabling experts throughout Europe to meet, exchange and innovate. "Physics on Stage" in 22 European Countries. "Physics on Stage" has been initiated in 22 European countries [2]. In each country, a dedicated National Steering Committee (NSC) is being formed which will be responsible for their own national programme. A list of contact addresses is attached below. "Physics on Stage" is based on a series of high-profile physics-related activities that will inform the European public in general, and European high school physics teachers and media representatives in particular

A Forceful Demonstration by FORS

NASA Astrophysics Data System (ADS)

1998-09-01

.). In addition, detailed computer software was provided to prepare the complex astronomical observations with FORS in advance and to monitor the instrument performance by quality checks of the scientific data accumulated. In return for building FORS for the community of European astrophysicists, the scientists in the three institutions of the FORS Consortium have received a certain amount of Guaranteed Observing Time at the VLT. This time will be used for various research projects concerned, among others, with minor bodies in the outer solar system, stars at late stages of their evolution and the clouds of gas they eject, as well as galaxies and quasars at very large distances, thereby permitting a look-back towards the early epoch of the universe. First tests of FORS1 at the VLT UT1: a great success After careful preparation, the FORS consortium has now started the so-called commissioning of the instrument. This comprises the thorough verification of the specified instrument properties at the telescope, checking the correct functioning under software control from the Paranal control room and, at the end of this process, a demonstration that the instrument fulfills its scientific purpose as planned. While performing these tests, the commissioning team at Paranal were able to obtain images of various astronomical objects, some of which are shown here. Two of these were obtained on the night of "FORS First Light". The photos demonstrate some of the impressive posibilities with this new instrument. They are based on observations with the FORS standard resolution collimator (field size 6.8 x 6.8 armin = 2048 x 2048 pixels; 1 pixel = 0.20 arcsec). Spiral galaxy NGC 1288 ESO PR Photo 37a/98 ESO PR Photo 37a/98 [Preview - JPEG: 800 x 908 pix - 224k] [High-Res - JPEG: 3000 x 3406 pix - 1.5Mb] A colour image of spiral galaxy NGC 1288, obtained on the night of "FORS First Light". The first photo shows a reproduction of a colour composite image of the beautiful spiral galaxy NGC

The ESO astronomical site monitor upgrade

NASA Astrophysics Data System (ADS)

Chiozzi, Gianluca; Sommer, Heiko; Sarazin, Marc; Bierwirth, Thomas; Dorigo, Dario; Vera Sequeiros, Ignacio; Navarrete, Julio; Del Valle, Diego

2016-08-01

Monitoring and prediction of astronomical observing conditions are essential for planning and optimizing observations. For this purpose, ESO, in the 90s, developed the concept of an Astronomical Site Monitor (ASM), as a facility fully integrated in the operations of the VLT observatory[1]. Identical systems were installed at Paranal and La Silla, providing comprehensive local weather information. By now, we had very good reasons for a major upgrade: • The need of introducing new features to satisfy the requirements of observing with the Adaptive Optics Facility and to benefit other Adaptive Optics systems. • Managing hardware and software obsolescence. • Making the system more maintainable and expandable by integrating off-the-shelf hardware solutions. The new ASM integrates: • A new Differential Image Motion Monitor (DIMM) paired with a Multi Aperture Scintillation Sensor (MASS) to measure the vertical distribution of turbulence in the high atmosphere and its characteristic velocity. • A new SLOpe Detection And Ranging (SLODAR) telescope, for measuring the altitude and intensity of turbulent layers in the low atmosphere. • A water vapour radiometer to monitor the water vapour content of the atmosphere. • The old weather tower, which is being refurbished with new sensors. The telescopes and the devices integrated are commercial products and we have used as much as possible the control system from the vendors. The existing external interfaces, based on the VLT standards, have been maintained for full backward compatibility. All data produced by the system are directly fed in real time into a relational database. A completely new web-based display replaces the obsolete plots based on HP-UX RTAP. We analyse here the architectural and technological choices and discuss the motivations and trade-offs.

The Gaia-ESO Survey: Calibration strategy

NASA Astrophysics Data System (ADS)

Pancino, E.; Lardo, C.; Altavilla, G.; Marinoni, S.; Ragaini, S.; Cocozza, G.; Bellazzini, M.; Sabbi, E.; Zoccali, M.; Donati, P.; Heiter, U.; Koposov, S. E.; Blomme, R.; Morel, T.; Símon-Díaz, S.; Lobel, A.; Soubiran, C.; Montalban, J.; Valentini, M.; Casey, A. R.; Blanco-Cuaresma, S.; Jofré, P.; Worley, C. C.; Magrini, L.; Hourihane, A.; François, P.; Feltzing, S.; Gilmore, G.; Randich, S.; Asplund, M.; Bonifacio, P.; Drew, J. E.; Jeffries, R. D.; Micela, G.; Vallenari, A.; Alfaro, E. J.; Allende Prieto, C.; Babusiaux, C.; Bensby, T.; Bragaglia, A.; Flaccomio, E.; Hambly, N.; Korn, A. J.; Lanzafame, A. C.; Smiljanic, R.; Van Eck, S.; Walton, N. A.; Bayo, A.; Carraro, G.; Costado, M. T.; Damiani, F.; Edvardsson, B.; Franciosini, E.; Frasca, A.; Lewis, J.; Monaco, L.; Morbidelli, L.; Prisinzano, L.; Sacco, G. G.; Sbordone, L.; Sousa, S. G.; Zaggia, S.; Koch, A.

2017-02-01

The Gaia-ESO survey (GES) is now in its fifth and last year of observations and has produced tens of thousands of high-quality spectra of stars in all Milky Way components. This paper presents the strategy behind the selection of astrophysical calibration targets, ensuring that all GES results on radial velocities, atmospheric parameters, and chemical abundance ratios will be both internally consistent and easily comparable with other literature results, especially from other large spectroscopic surveys and from Gaia. The calibration of GES is particularly delicate because of (I) the large space of parameters covered by its targets, ranging from dwarfs to giants, from O to M stars; these targets have a large wide of metallicities and also include fast rotators, emission line objects, and stars affected by veiling; (II) the variety of observing setups, with different wavelength ranges and resolution; and (III) the choice of analyzing the data with many different state-of-the-art methods, each stronger in a different region of the parameter space, which ensures a better understanding of systematic uncertainties. An overview of the GES calibration and homogenization strategy is also given, along with some examples of the usage and results of calibrators in GES iDR4, which is the fourth internal GES data release and will form the basis of the next GES public data release. The agreement between GES iDR4 recommended values and reference values for the calibrating objects are very satisfactory. The average offsets and spreads are generally compatible with the GES measurement errors, which in iDR4 data already meet the requirements set by the main GES scientific goals. Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under programme IDs 188.B-3002 and 193.B-0936.Full Table 2 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http

Back-stepping active disturbance rejection control design for integrated missile guidance and control system via reduced-order ESO.

PubMed

Xingling, Shao; Honglun, Wang

2015-07-01

This paper proposes a novel composite integrated guidance and control (IGC) law for missile intercepting against unknown maneuvering target with multiple uncertainties and control constraint. First, by using back-stepping technique, the proposed IGC law design is separated into guidance loop and control loop. The unknown target maneuvers and variations of aerodynamics parameters in guidance and control loop are viewed as uncertainties, which are estimated and compensated by designed model-assisted reduced-order extended state observer (ESO). Second, based on the principle of active disturbance rejection control (ADRC), enhanced feedback linearization (FL) based control law is implemented for the IGC model using the estimates generated by reduced-order ESO. In addition, performance analysis and comparisons between ESO and reduced-order ESO are examined. Nonlinear tracking differentiator is employed to construct the derivative of virtual control command in the control loop. Third, the closed-loop stability for the considered system is established. Finally, the effectiveness of the proposed IGC law in enhanced interception performance such as smooth interception course, improved robustness against multiple uncertainties as well as reduced control consumption during initial phase are demonstrated through simulations. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

Charting the Giants

NASA Astrophysics Data System (ADS)

2004-06-01

Largest Census Of X-Ray Galaxy Clusters Provides New Constraints on Dark Matter [1] Clusters of galaxies Clusters of galaxies are very large building blocks of the Universe. These gigantic structures contain hundreds to thousands of galaxies and, less visible but equally interesting, an additional amount of "dark matter" whose origin still defies the astronomers, with a total mass of thousands of millions of millions times the mass of our Sun. The comparatively nearby Coma cluster, for example, contains thousands of galaxies and measures more than 20 million light-years across. Another well-known example is the Virgo cluster at a distance of about 50 million light-years, and still stretching over an angle of more than 10 degrees in the sky! Clusters of galaxies form in the densest regions of the Universe. As such, they perfectly trace the backbone of the large-scale structures in the Universe, in the same way that lighthouses trace a coastline. Studies of clusters of galaxies therefore tell us about the structure of the enormous space in which we live. The REFLEX survey ESO PR Photo 18a/04 ESO PR Photo 18a/04 Galaxy Cluster RXCJ 1206.2-0848 (Visible and X-ray) [Preview - JPEG: 400 x 478 pix - 70k] [Normal - JPEG: 800 x 956 pix - 1.2Mk] Caption: PR Photo 18a shows the very massive distant cluster of galaxies RXCJ1206.2-0848, newly discovered during the REFLEX project, and located at a redshift of z = 0.44 [3]. The contours indicate the X-ray surface brightness distribution. Most of the yellowish galaxies are cluster members. A gravitationally lensed galaxy with a distorted, very elongated image is seen, just right of the centre. The image was obtained with the EFOSC multi-mode instrument on the ESO 3.6-m telescope at the La Silla Observatory (Chile). ESO PR Photo 18b/04 ESO PR Photo 18b/04 Galaxy cluster RXCJ1131.9-1955 [Preview - JPEG: 400 x 477 pix - 40k] [Normal - JPEG: 800 x 953 pix - 912k] [FullRes - JPEG: 2251 x 2681 pix - 7.7Mk] Caption: PR Photo 18b displays

ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67

PubMed Central

2010-01-01

Introduction Accurate assessment of estrogen receptor (ER), progesterone receptor (PR), and Ki-67 is essential in the histopathologic diagnostics of breast cancer. Commercially available image analysis systems are usually bundled with dedicated analysis hardware and, to our knowledge, no easily installable, free software for immunostained slide scoring has been described. In this study, we describe a free, Internet-based web application for quantitative image analysis of ER, PR, and Ki-67 immunohistochemistry in breast cancer tissue sections. Methods The application, named ImmunoRatio, calculates the percentage of positively stained nuclear area (labeling index) by using a color deconvolution algorithm for separating the staining components (diaminobenzidine and hematoxylin) and adaptive thresholding for nuclear area segmentation. ImmunoRatio was calibrated using cell counts defined visually as the gold standard (training set, n = 50). Validation was done using a separate set of 50 ER, PR, and Ki-67 stained slides (test set, n = 50). In addition, Ki-67 labeling indexes determined by ImmunoRatio were studied for their prognostic value in a retrospective cohort of 123 breast cancer patients. Results The labeling indexes by calibrated ImmunoRatio analyses correlated well with those defined visually in the test set (correlation coefficient r = 0.98). Using the median Ki-67 labeling index (20%) as a cutoff, a hazard ratio of 2.2 was obtained in the survival analysis (n = 123, P = 0.01). ImmunoRatio was shown to adapt to various staining protocols, microscope setups, digital camera models, and image acquisition settings. The application can be used directly with web browsers running on modern operating systems (e.g., Microsoft Windows, Linux distributions, and Mac OS). No software downloads or installations are required. ImmunoRatio is open source software, and the web application is publicly accessible on our website. Conclusions We anticipate that free web applications

ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67.

PubMed

Tuominen, Vilppu J; Ruotoistenmäki, Sanna; Viitanen, Arttu; Jumppanen, Mervi; Isola, Jorma

2010-01-01

Accurate assessment of estrogen receptor (ER), progesterone receptor (PR), and Ki-67 is essential in the histopathologic diagnostics of breast cancer. Commercially available image analysis systems are usually bundled with dedicated analysis hardware and, to our knowledge, no easily installable, free software for immunostained slide scoring has been described. In this study, we describe a free, Internet-based web application for quantitative image analysis of ER, PR, and Ki-67 immunohistochemistry in breast cancer tissue sections. The application, named ImmunoRatio, calculates the percentage of positively stained nuclear area (labeling index) by using a color deconvolution algorithm for separating the staining components (diaminobenzidine and hematoxylin) and adaptive thresholding for nuclear area segmentation. ImmunoRatio was calibrated using cell counts defined visually as the gold standard (training set, n = 50). Validation was done using a separate set of 50 ER, PR, and Ki-67 stained slides (test set, n = 50). In addition, Ki-67 labeling indexes determined by ImmunoRatio were studied for their prognostic value in a retrospective cohort of 123 breast cancer patients. The labeling indexes by calibrated ImmunoRatio analyses correlated well with those defined visually in the test set (correlation coefficient r = 0.98). Using the median Ki-67 labeling index (20%) as a cutoff, a hazard ratio of 2.2 was obtained in the survival analysis (n = 123, P = 0.01). ImmunoRatio was shown to adapt to various staining protocols, microscope setups, digital camera models, and image acquisition settings. The application can be used directly with web browsers running on modern operating systems (e.g., Microsoft Windows, Linux distributions, and Mac OS). No software downloads or installations are required. ImmunoRatio is open source software, and the web application is publicly accessible on our website. We anticipate that free web applications, such as ImmunoRatio, will make the

THE NARROW X-RAY TAIL AND DOUBLE Hα TAILS OF ESO 137-002 IN A3627

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, B.; Lin, X. B.; Kong, X.

2013-11-10

We present the analysis of a deep Chandra observation of a ∼2 L{sub *} late-type galaxy, ESO 137-002, in the closest rich cluster A3627. The Chandra data reveal a long (∼>40 kpc) and narrow tail with a nearly constant width (∼3 kpc) to the southeast of the galaxy, and a leading edge ∼1.5 kpc from the galaxy center on the upstream side of the tail. The tail is most likely caused by the nearly edge-on stripping of ESO 137-002's interstellar medium (ISM) by ram pressure, compared to the nearly face-on stripping of ESO 137-001 discussed in our previous work. Spectralmore » analysis of individual regions along the tail shows that the gas throughout it has a rather constant temperature, ∼1 keV, very close to the temperature of the tails of ESO 137-001, if the same atomic database is used. The derived gas abundance is low (∼0.2 solar with the single-kT model), an indication of the multiphase nature of the gas in the tail. The mass of the X-ray tail is only a small fraction (<5%) of the initial ISM mass of the galaxy, suggesting that the stripping is most likely at an early stage. However, with any of the single-kT, double-kT, and multi-kT models we tried, the tail is always 'over-pressured' relative to the surrounding intracluster medium (ICM), which could be due to the uncertainties in the abundance, thermal versus non-thermal X-ray emission, or magnetic support in the ICM. The Hα data from the Southern Observatory for Astrophysical Research show a ∼21 kpc tail spatially coincident with the X-ray tail, as well as a secondary tail (∼12 kpc long) to the east of the main tail diverging at an angle of ∼23° and starting at a distance of ∼7.5 kpc from the nucleus. At the position of the secondary Hα tail, the X-ray emission is also enhanced at the ∼2σ level. We compare the tails of ESO 137-001 and ESO 137-002, and also compare the tails to simulations. Both the similarities and differences of the tails pose challenges to the simulations. Several

Free from the Atmosphere

NASA Astrophysics Data System (ADS)

2007-06-01

An artificial, laser-fed star now shines regularly over the sky of Paranal, home of ESO's Very Large Telescope, one of the world's most advanced large ground-based telescopes. This system provides assistance for the adaptive optics instruments on the VLT and so allows astronomers to obtain images free from the blurring effect of the atmosphere, regardless of the brightness and the location on the sky of the observed target. Now that it is routinely offered by the observatory, the skies seem much sharper to astronomers. In order to counteract the blurring effect of Earth's atmosphere, astronomers use the adaptive optics technique. This requires, however, a nearby reference star that has to be relatively bright, thereby limiting the area of the sky that can be surveyed. To surmount this limitation, astronomers now use at Paranal a powerful laser that creates an artificial star, where and when they need it. Two of the Adaptive Optics (AO) science instruments at the Paranal observatory, NACO and SINFONI, have been upgraded to work with the recently installed Laser Guide Star (LGS; see ESO 07/06) and have delivered their first scientific results. This achievement opens astronomers' access to a wealth of new targets to be studied under the sharp eyes of AO. "These unique results underline the advantage of using a Laser Guide Star with Adaptive Optics instruments, since they could not be obtained with Natural Guide Stars," says Norbert Hubin, head of the Adaptive Optics group at ESO. "This is also a crucial milestone towards the multi-laser systems ESO is designing for the VLT and the future E-ELT" (see e.g. ESO 19/07). ESO PR Photo 27a/07 ESO PR Photo 27a/07 An Ultra Luminous Merger (NACO-LGS/VLT) The Laser Guide Star System installed at Paranal uses the PARSEC dye laser developed by MPE-Garching and MPIA-Heidelberg, while the launch telescope and the laser laboratory was developed by ESO. "It is great to see the whole system working so well together," emphasises Richard

Back on Track

NASA Astrophysics Data System (ADS)

2007-06-01

An artificial, laser-fed star now shines regularly over the sky of Paranal, home of ESO's Very Large Telescope, one of the world's most advanced large ground-based telescopes. This system provides assistance for the adaptive optics instruments on the VLT and so allows astronomers to obtain images free from the blurring effect of the atmosphere, regardless of the brightness and the location on the sky of the observed target. Now that it is routinely offered by the observatory, the skies seem much sharper to astronomers. In order to counteract the blurring effect of Earth's atmosphere, astronomers use the adaptive optics technique. This requires, however, a nearby reference star that has to be relatively bright, thereby limiting the area of the sky that can be surveyed. To surmount this limitation, astronomers now use at Paranal a powerful laser that creates an artificial star, where and when they need it. Two of the Adaptive Optics (AO) science instruments at the Paranal observatory, NACO and SINFONI, have been upgraded to work with the recently installed Laser Guide Star (LGS; see ESO 07/06) and have delivered their first scientific results. This achievement opens astronomers' access to a wealth of new targets to be studied under the sharp eyes of AO. "These unique results underline the advantage of using a Laser Guide Star with Adaptive Optics instruments, since they could not be obtained with Natural Guide Stars," says Norbert Hubin, head of the Adaptive Optics group at ESO. "This is also a crucial milestone towards the multi-laser systems ESO is designing for the VLT and the future E-ELT" (see e.g. ESO 19/07). ESO PR Photo 27a/07 ESO PR Photo 27a/07 An Ultra Luminous Merger (NACO-LGS/VLT) The Laser Guide Star System installed at Paranal uses the PARSEC dye laser developed by MPE-Garching and MPIA-Heidelberg, while the launch telescope and the laser laboratory was developed by ESO. "It is great to see the whole system working so well together," emphasises Richard

Introducing CUBES: the Cassegrain U-band Brazil-ESO spectrograph

NASA Astrophysics Data System (ADS)

Bristow, Paul; Barbuy, Beatriz; Macanhan, Vanessa B.; Castilho, Bruno; Dekker, Hans; Delabre, Bernard; Diaz, Marcos; Gneiding, Clemens; Kerber, Florian; Kuntschner, Harald; La Mura, Giovanni; Reiss, Roland; Vernet, J.

2014-07-01

CUBES is a high-efficiency, medium-resolution (R ≃ 20, 000) spectrograph dedicated to the "ground based UV" (approximately the wavelength range from 300 to 400nm) destined for the Cassegrain focus of one of ESO's VLT unit telescopes in 2018/19. The CUBES project is a joint venture between ESO and Instituto de Astronomia, Geofísica e Ciências Atmosféricas (IAG) at the Universidade de São Paulo and the Brazilian Laboratório Nacional de Astrofísica (LNA). CUBES will provide access to a wealth of new and relevant information for stellar as well as extra-galactic sources. Principle science cases include the study of heavy elements in metal-poor stars, the direct determination of carbon, nitrogen and oxygen abundances by study of molecular bands in the UV range and the determination of the Beryllium abundance as well as the study of active galactic nuclei and the inter-galactic medium. With a streamlined modern instrument design, high efficiency dispersing elements and UV-sensitive detectors, it will enable a significant gain in sensitivity over existing ground based medium-high resolution spectrographs enabling vastly increased sample sizes accessible to the astronomical community. We present here a brief overview of the project, introducing the science cases that drive the design and discussing the design options and technological challenges.

News from ESO Archive Services: Next Generation Request Handler and Data Access Delegation

NASA Astrophysics Data System (ADS)

Fourniol, N.; Lockhart, J.; Suchar, D.; Tacconi-Garman, L. E.; Moins, C.; Bierwirth, T.; Eglitis, P.; Vuong, M.; Micol, A.; Delmotte, N.; Vera, I.; Dobrzycki, A.; Forchì, V.; Lange, U.; Sogni, F.

2012-09-01

We present the new ESO Archive services which improve the electronic data access via the Download Manager and also provide PIs with the option to delegate data access to their collaborators via the Data Access Control.

Nearest Cosmic Mirage

NASA Astrophysics Data System (ADS)

2003-07-01

Discovery of quadruply lensed quasar with Einstein ring Summary Using the ESO 3.6-m telescope at La Silla (Chile), an international team of astronomers [1] has discovered a complex cosmic mirage in the southern constellation Crater (The Cup). This "gravitational lens" system consists of (at least) four images of the same quasar as well as a ring-shaped image of the galaxy in which the quasar resides - known as an "Einstein ring". The more nearby lensing galaxy that causes this intriguing optical illusion is also well visible. The team obtained spectra of these objects with the new EMMI camera mounted on the ESO 3.5-m New Technology Telescope (NTT), also at the La Silla observatory. They find that the lensed quasar [2] is located at a distance of 6,300 million light-years (its "redshift" is z = 0.66 [3]) while the lensing elliptical galaxy is rougly halfway between the quasar and us, at a distance of 3,500 million light-years (z = 0.3). The system has been designated RXS J1131-1231 - it is the closest gravitationally lensed quasar discovered so far . PR Photo 20a/03 : Image of the gravitational lens system RXS J1131-1231 (ESO 3.6m Telescope). PR Photo 20b/03 : Spectra of two lensed images of the source quasar and the lensing galaxy. Cosmic mirages The physical principle behind a "gravitational lens" (also known as a "cosmic mirage") has been known since 1916 as a consequence of Albert Einstein's Theory of General Relativity . The gravitational field of a massive object curves the local geometry of the Universe, so light rays passing close to the object are bent (like a "straight line" on the surface of the Earth is necessarily curved because of the curvature of the Earth's surface). This effect was first observed by astronomers in 1919 during a total solar eclipse. Accurate positional measurements of stars seen in the dark sky near the eclipsed Sun indicated an apparent displacement in the direction opposite to the Sun, about as much as predicted by Einstein

Integration of the instrument control electronics for the ESPRESSO spectrograph at ESO-VLT

NASA Astrophysics Data System (ADS)

Baldini, V.; Calderone, G.; Cirami, R.; Coretti, I.; Cristiani, S.; Di Marcantonio, P.; Mégevand, D.; Riva, M.; Santin, P.

2016-07-01

ESPRESSO, the Echelle SPectrograph for Rocky Exoplanet and Stable Spectroscopic Observations of the ESO - Very Large Telescope site, is now in its integration phase. The large number of functions of this complex instrument are fully controlled by a Beckhoff PLC based control electronics architecture. Four small and one large cabinets host the main electronic parts to control all the sensors, motorized stages and other analogue and digital functions of ESPRESSO. The Instrument Control Electronics (ICE) is built following the latest ESO standards and requirements. Two main PLC CPUs are used and are programmed through the TwinCAT Beckhoff dedicated software. The assembly, integration and verification phase of ESPRESSO, due to its distributed nature and different geographical locations of the consortium partners, is quite challenging. After the preliminary assembling and test of the electronic components at the Astronomical Observatory of Trieste and the test of some electronics and software parts at ESO (Garching), the complete system for the control of the four Front End Unit (FEU) arms of ESPRESSO has been fully assembled and tested in Merate (Italy) at the beginning of 2016. After these first tests, the system will be located at the Geneva Observatory (Switzerland) until the Preliminary Acceptance Europe (PAE) and finally shipped to Chile for the commissioning. This paper describes the integration strategy of the ICE workpackage of ESPRESSO, the hardware and software tests that have been performed, with an overall view of the experience gained during these project's phases.

Observing facilities at the European Southern Observatory (ESO) in Chile for cometary observations

NASA Technical Reports Server (NTRS)

Schnur, G. F. O.; Kohoutek, L.; Rahe, J.

1981-01-01

The (ESO) is located on the mountain La Silla (geographical coordinates: 4h42m55s10 west, -29 deg 15' 25".8 south, 2400 m elevation. The size of the telescopes ranges from a 40 cm Astrograph to the 3.6 m Richey-Chretien telescope. Future telescopes are discussed: a 2.2 m RC-Telescope which will be identical with the German 2.2 m telescope on Calor Alto in SE-Spain, and a 3.5 m telescope, the New Technology Telescope. In addition to these telescopes, a great number of auxiliary instrumentation are operational. Because ESO has to serve all requests of the visiting astronomers these instruments are designed for very different applications. The telescopes and auxiliary instruments that are especially suited for cometary observations are discussed. The dicussion is divided into three parts: photography, photometry-polarimetry and spectroscopy.

New Fast Lane towards Discoveries of Clusters of Galaxies Inaugurated

NASA Astrophysics Data System (ADS)

2003-07-01

Space and Ground-Based Telescopes Cooperate to Gain Deep Cosmological Insights Summary Using the ESA XMM-Newton satellite, a team of European and Chilean astronomers [2] has obtained the world's deepest "wide-field" X-ray image of the cosmos to date. This penetrating view, when complemented with observations by some of the largest and most efficient ground-based optical telescopes, including the ESO Very Large Telescope (VLT), has resulted in the discovery of several large clusters of galaxies. These early results from an ambitious research programme are extremely promising and pave the way for a very comprehensive and thorough census of clusters of galaxies at various epochs. Relying on the foremost astronomical technology and with an unequalled observational efficiency, this project is set to provide new insights into the structure and evolution of the distant Universe. PR Photo 19a/03: First image from the XMM-LSS survey. PR Photo 19b/03: Zoom-in on PR Photo 19b/03. PR Photo 19c/03: XMM-Newton contour map of the probable extent of a cluster of galaxies, superimposed upon a CHFT I-band image. PR Photo 19d/03: Velocity distribution in the cluster field shown in PR Photo 19c/03. The universal web Unlike grains of sand on a beach, matter is not uniformly spread throughout the Universe. Instead, it is concentrated into galaxies which themselves congregate into clusters (and even clusters of clusters). These clusters are "strung" throughout the Universe in a web-like structure, cf. ESO PR 11/01. Our Galaxy, the Milky Way, for example, belongs to the so-called Local Group which also comprises "Messier 31", the Andromeda Galaxy. The Local Group contains about 30 galaxies and measures a few million light-years across. Other clusters are much larger. The Coma cluster contains thousands of galaxies and measures more than 20 million light-years. Another well known example is the Virgo cluster, covering no less than 10 degrees on the sky ! Clusters of galaxies are the most

Astronomer's new guide to the galaxy: largest map of cold dust revealed

NASA Astrophysics Data System (ADS)

2009-07-01

Astronomers have unveiled an unprecedented new atlas of the inner regions of the Milky Way, our home galaxy, peppered with thousands of previously undiscovered dense knots of cold cosmic dust -- the potential birthplaces of new stars. Made using observations from the APEX telescope in Chile, this survey is the largest map of cold dust so far, and will prove an invaluable map for observations made with the forthcoming ALMA telescope, as well as the recently launched ESA Herschel space telescope. ESO PR Photo 24a/09 View of the Galactic Plane from the ATLASGAL survey (annotated and in five sections) ESO PR Photo 24b/09 View of the Galactic Plane from the ATLASGAL survey (annotated) ESO PR Photo 24c/09 View of the Galactic Plane from the ATLASGAL survey (in five sections) ESO PR Photo 24d/09 View of the Galactic Plane from the ATLASGAL survey ESO PR Photo 24e/09 The Galactic Centre and Sagittarius B2 ESO PR Photo 24f/09 The NGC 6357 and NGC 6334 nebulae ESO PR Photo 24g/09 The RCW120 nebula ESO PR Video 24a/09 Annotated pan as seen by the ATLASGAL survey This new guide for astronomers, known as the APEX Telescope Large Area Survey of the Galaxy (ATLASGAL) shows the Milky Way in submillimetre-wavelength light (between infrared light and radio waves [1]). Images of the cosmos at these wavelengths are vital for studying the birthplaces of new stars and the structure of the crowded galactic core. "ATLASGAL gives us a new look at the Milky Way. Not only will it help us investigate how massive stars form, but it will also give us an overview of the larger-scale structure of our galaxy", said Frederic Schuller from the Max Planck Institute for Radio Astronomy, leader of the ATLASGAL team. The area of the new submillimetre map is approximately 95 square degrees, covering a very long and narrow strip along the galactic plane two degrees wide (four times the width of the full Moon) and over 40 degrees long. The 16 000 pixel-long map was made with the LABOCA submillimetre

PR-PR: cross-platform laboratory automation system.

PubMed

Linshiz, Gregory; Stawski, Nina; Goyal, Garima; Bi, Changhao; Poust, Sean; Sharma, Monica; Mutalik, Vivek; Keasling, Jay D; Hillson, Nathan J

2014-08-15

To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Golden Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.

The Gaia-ESO Survey: open clusters in Gaia-DR1 . A way forward to stellar age calibration

NASA Astrophysics Data System (ADS)

Randich, S.; Tognelli, E.; Jackson, R.; Jeffries, R. D.; Degl'Innocenti, S.; Pancino, E.; Re Fiorentin, P.; Spagna, A.; Sacco, G.; Bragaglia, A.; Magrini, L.; Prada Moroni, P. G.; Alfaro, E.; Franciosini, E.; Morbidelli, L.; Roccatagliata, V.; Bouy, H.; Bravi, L.; Jiménez-Esteban, F. M.; Jordi, C.; Zari, E.; Tautvaišiene, G.; Drazdauskas, A.; Mikolaitis, S.; Gilmore, G.; Feltzing, S.; Vallenari, A.; Bensby, T.; Koposov, S.; Korn, A.; Lanzafame, A.; Smiljanic, R.; Bayo, A.; Carraro, G.; Costado, M. T.; Heiter, U.; Hourihane, A.; Jofré, P.; Lewis, J.; Monaco, L.; Prisinzano, L.; Sbordone, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2018-05-01

Context. Determination and calibration of the ages of stars, which heavily rely on stellar evolutionary models, are very challenging, while representing a crucial aspect in many astrophysical areas. Aims: We describe the methodologies that, taking advantage of Gaia-DR1 and the Gaia-ESO Survey data, enable the comparison of observed open star cluster sequences with stellar evolutionary models. The final, long-term goal is the exploitation of open clusters as age calibrators. Methods: We perform a homogeneous analysis of eight open clusters using the Gaia-DR1 TGAS catalogue for bright members and information from the Gaia-ESO Survey for fainter stars. Cluster membership probabilities for the Gaia-ESO Survey targets are derived based on several spectroscopic tracers. The Gaia-ESO Survey also provides the cluster chemical composition. We obtain cluster parallaxes using two methods. The first one relies on the astrometric selection of a sample of bona fide members, while the other one fits the parallax distribution of a larger sample of TGAS sources. Ages and reddening values are recovered through a Bayesian analysis using the 2MASS magnitudes and three sets of standard models. Lithium depletion boundary (LDB) ages are also determined using literature observations and the same models employed for the Bayesian analysis. Results: For all but one cluster, parallaxes derived by us agree with those presented in Gaia Collaboration (2017, A&A, 601, A19), while a discrepancy is found for NGC 2516; we provide evidence supporting our own determination. Inferred cluster ages are robust against models and are generally consistent with literature values. Conclusions: The systematic parallax errors inherent in the Gaia DR1 data presently limit the precision of our results. Nevertheless, we have been able to place these eight clusters onto the same age scale for the first time, with good agreement between isochronal and LDB ages where there is overlap. Our approach appears promising

PR-PR: Cross-Platform Laboratory Automation System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linshiz, G; Stawski, N; Goyal, G

To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Goldenmore » Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.« less

System analysis tools for an ELT at ESO

NASA Astrophysics Data System (ADS)

Mueller, Michael; Koch, Franz

2006-06-01

Engineering of complex, large scale systems like the ELT designs currently investigated and developed in Europe and Northern America require powerful and sophisticated tools within specific technical disciplines such as mechanics, optics and control engineering. However, even analyzing a certain component of the telescope like the telescope structure necessitates a system approach to evaluate the structural effects onto the optical performance. This paper shows several software tools developed by the European Southern Observatory (ESO) which focus onto the system approach in the analyses: Using modal results of a finite element analysis the SMI-toolbox allows an easy generation of structural models with different sizes and levels of accuracy for the control design and closed-loop simulations. The optical modeling code BeamWarrior was developed by ESO and Astrium GmbH, Germany) especially for integrated modeling and interfering with a structural model. Within BeamWarrior displacements and deformations can be applied in an arbitrary coordinate system, and hence also in the global coordinates of the FE model avoiding error prone transformations. In addition to this, a sparse state space model object was developed for Matlab to gain in computational efficiency and reduced memory requirements due to the sparsity pattern of both the structural models and the control architecture. As one result these tools allow building an integrated model in order to reliably simulate interactions, cross-coupling effects, system responses, and to evaluate global performance. In order to evaluate disturbance effects on the optical performance in openloop more efficiently, an optical evaluation toolbox was built in the FE software ANSYS which performs Zernike decomposition and best-fit computation of the deformations directly in the FE analysis.

Adaptive optics for the ESO-VLT

NASA Astrophysics Data System (ADS)

Merkle, Fritz

1989-04-01

This paper discusses adaptive optics, its performance, and its requirements for applications in astronomy to overcome limitations due to atmospheric turbulence. Guidelines for the implementation of these devices in telescopes are given, in particular for the Very Large Telescope (VLT) at ESO. It is intended to equip each one of the four 8-m telescopes of the VLT, which are arranged in a linear array with an independent adaptive optical system. These systems will serve the individual and the combined coude foci. A small-scale prototype adaptive system is under development. It is equipped with a 19-piezoelectric-actuator deformable mirror, a Shack-Hartmann-type wavefront sensor, and a dedicated wavefront computer for closing the feedback loop. This system is based on a polychromatic approach; i.e., it senses the wavefront in the visible, but the adaptive correction loop works at 3-5 microns.

Late Afternoon at Taruntius

NASA Astrophysics Data System (ADS)

2002-08-01

Thirty-three years after the first manned landing on the Moon, the ESO Very Large Telescope (VLT) has obtained what may be the sharpest image of the lunar surface ever recorded from the ground, cf. PR Photo 19a/02 . It was made with the NAOS-CONICA (NACO) adaptive optics camera mounted on the ESO VLT 8.2-m YEPUN telescope at the Paranal Observatory. The photo shows an area about 700 km from the Apollo XI landing site. The location is in the Eastern hemisphere, just North of the lunar equator, and right between two of the major "seas", Mare Tranquillitatis (Sea of Tranquillity) and Mare Foecunditatis (Sea of Fertility). The field-of-view measures about 60 x 45 km 2 (taking into account the foreshortening because of the viewing angle [2]), with part of a sunlit, 10-km wide crater named Cameron [1] surrounded by a comparatively level terrain, bordered by some hills and, not least, with an incredible number of smaller craters. The site of this NACO photo is situated at the rim of an older, rather eroded 56-km crater, Taruntius [1]. A small part of the multiple walls of that crater are seen in the upper right corner and also to the left of the bottom centre of PR Photo 19a/02 . The centre of Taruntius is near the lower right corner of the photo. The rather flat terrain to the left in the photo corresponds to an "opening" in the crater walls. At the time of the exposure, the Sun was approximately 7° above the Western horizon to the left [2], and the shadows are therefore quite prominent, approx. 8 times longer than the elevation of the corresponding peaks and hills. The nominal image sharpness is 0.07 arcsec, or about 130 metres on the lunar surface (in the N-S direction). Elevation differences of a few tens of metres only are therefore visible by the shadows they cast. The VLT image represents what an astronaut (with normal eye acuity of 1 arcmin) would see from 400 km above the surface. Lunar surface formations ESO PR Photo 19b/02 ESO PR Photo 19b/02 [Preview - JPEG

ESO Advanced Data Products for the Virtual Observatory

NASA Astrophysics Data System (ADS)

Retzlaff, J.; Delmotte, N.; Rite, C.; Rosati, P.; Slijkhuis, R.; Vandame, B.

2006-07-01

Advanced Data Products, that is, completely reduced, fully characterized science-ready data sets, play a crucial role for the success of the Virtual Observatory as a whole. We report on on-going work at ESO towards the creation and publication of Advanced Data Products in compliance with present VO standards on resource metadata. The new deep NIR multi-color mosaic of the GOODS/CDF-S region is used to showcase different aspects of the entire process: data reduction employing our MVM-based reduction pipeline, calibration and data characterization procedures, standardization of metadata content, and, finally, a prospect of the scientific potential illustrated by new results on deep galaxy number counts.

Stellar Family Portrait Takes Imaging Technique to New Extremes

NASA Astrophysics Data System (ADS)

2009-12-01

The young star cluster Trumpler 14 is revealed in another stunning ESO image. The amount of exquisite detail seen in this portrait, which beautifully reveals the life of a large family of stars, is due to the Multi-conjugate Adaptive optics Demonstrator (MAD) on ESO's Very Large Telescope. Never before has such a large patch of sky been imaged using adaptive optics [1], a technique by which astronomers are able to remove most of the atmosphere's blurring effects. Noted for harbouring Eta Carinae - one of the wildest and most massive stars in our galaxy - the impressive Carina Nebula also houses a handful of massive clusters of young stars. The youngest of these stellar families is the Trumpler 14 star cluster, which is less than one million years old - a blink of an eye in the Universe's history. This large open cluster is located some 8000 light-years away towards the constellation of Carina (the Keel). A team of astronomers, led by Hugues Sana, acquired astounding images of the central part of Trumpler 14 using the Multi-conjugate Adaptive optics Demonstrator (MAD, [2]) mounted on ESO's Very Large Telescope (VLT). Thanks to MAD, astronomers were able to remove most of the blurring effects of the atmosphere and thus obtain very sharp images. MAD performs this correction over a much larger patch of the sky than any other current adaptive optics instrument, allowing astronomers to make wider, crystal-clear images. Thanks to the high quality of the MAD images, the team of astronomers could obtain a very nice family portrait. They found that Trumpler 14 is not only the youngest - with a refined, newly estimated age of just 500 000 years - but also one of the most populous star clusters within the nebula. The astronomers counted about 2000 stars in their image, spanning the whole range from less than one tenth up to a factor of several tens of times the mass of our own Sun. And this in a region which is only about six light-years across, that is, less than twice the

Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck.

PubMed

Veit, Johannes A; Heine, Daniela; Thierauf, Julia; Lennerz, Jochen; Shetty, Subasch; Schuler, Patrick J; Whiteside, Theresa; Beutner, Dirk; Meyer, Moritz; Grünewald, Inga; Ritter, Gerd; Gnjatic, Sacha; Sikora, Andrew G; Hoffmann, Thomas K; Laban, Simon

2016-07-01

Adenoid cystic carcinoma (ACC) of the head and neck is a rare but highly malignant tumor. Cancer-testis antigens (CTAs) represent an immunogenic family of cancer-specific proteins and thus represent an attractive target for immunotherapy. Eighty-four cases of ACC were identified, the CTAs pan-Melanoma antigen (pan-MAGE; M3H67) and New York esophageal squamous cell carcinoma (NY-ESO-1; E978) were detected immunohistochemically (IHC) and correlated with clinical data. Expression of NY-ESO-1 was found in 48 of 84 patients (57.1%) and of pan-MAGE in 28 of 84 patients (31.2%). Median overall survival (OS) in NY-ESO-1 positive versus negative patients was 130.8 and 282.0 months (p = .223), respectively. OS in pan-MAGE positive versus negative patients was 105.3 and 190.5 months, respectively (p = .096). Patients expressing both NY-ESO-1 and pan-MAGE simultaneously had significantly reduced OS with a median of 90.5 months compared with 282.0 months in negative patients (p = .047). A significant fraction of patients with ACC show expression of the CTAs NY-ESO-1 and/or pan-MAGE with promising immunotherapeutic implications. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1008-1016, 2016. © 2016 Wiley Periodicals, Inc.

Strong Winds over the Keel

NASA Astrophysics Data System (ADS)

2009-02-01

The latest ESO image reveals amazing detail in the intricate structures of one of the largest and brightest nebulae in the sky, the Carina Nebula (NGC 3372), where strong winds and powerful radiation from an armada of massive stars are creating havoc in the large cloud of dust and gas from which the stars were born. ESO PR Photo 05a/09 The Carina Nebula ESO PR Video 05a/09 Pan over the Carina Nebula ESO PR Video 05b/09 Carina Nebula Zoom-in The large and beautiful image displays the full variety of this impressive skyscape, spattered with clusters of young stars, large nebulae of dust and gas, dust pillars, globules, and adorned by one of the Universe's most impressive binary stars. It was produced by combining exposures through six different filters from the Wide Field Imager (WFI), attached to the 2.2 m ESO/MPG telescope at ESO's La Silla Observatory, in Chile. The Carina Nebula is located about 7500 light-years away in the constellation of the same name (Carina; the Keel). Spanning about 100 light-years, it is four times larger than the famous Orion Nebula and far brighter. It is an intensive star-forming region with dark lanes of cool dust splitting up the glowing nebula gas that surrounds its many clusters of stars. The glow of the Carina Nebula comes mainly from hot hydrogen basking in the strong radiation of monster baby stars. The interaction between the hydrogen and the ultraviolet light results in its characteristic red and purple colour. The immense nebula contains over a dozen stars with at least 50 to 100 times the mass of our Sun. Such stars have a very short lifespan, a few million years at most, the blink of an eye compared with the Sun's expected lifetime of ten billion years. One of the Universe's most impressive stars, Eta Carinae, is found in the nebula. It is one of the most massive stars in our Milky Way, over 100 times the mass of the Sun and about four million times brighter, making it the most luminous star known. Eta Carinae is highly

The Topsy-Turvy Galaxy

NASA Astrophysics Data System (ADS)

2006-11-01

The captivating appearance of this image of the starburst galaxy NGC 1313, taken with the FORS instrument at ESO's Very Large Telescope, belies its inner turmoil. The dense clustering of bright stars and gas in its arms, a sign of an ongoing boom of star births, shows a mere glimpse of the rough times it has seen. Probing ever deeper into the heart of the galaxy, astronomers have revealed many enigmas that continue to defy our understanding. ESO PR Photo 43a/06 ESO PR Photo 43a/06 The Topsy-Turvy Galaxy NGC 1313 This FORS image of the central parts of NGC 1313 shows a stunning natural beauty. The galaxy bears some resemblance to some of the Milky Way's closest neighbours, the Magellanic Clouds. NGC 1313 has a barred spiral shape, with the arms emanating outwards in a loose twist from the ends of the bar. The galaxy lies just 15 million light-years away from the Milky Way - a mere skip on cosmological scales. The spiral arms are a hotbed of star-forming activity, with numerous young clusters of hot stars being born continuously at a staggering rate out of the dense clouds of gas and dust. Their light blasts through the surrounding gas, creating an intricately beautiful pattern of light and dark nebulosity. But NGC 1313 is not just a pretty picture. A mere scratch beneath the elegant surface reveals evidence of some of the most puzzling problems facing astronomers in the science of stars and galaxies. Starburst galaxies are fascinating objects to study in their own right; in neighbouring galaxies, around one quarter of all massive stars are born in these powerful engines, at rates up to a thousand times higher than in our own Milky Way Galaxy. In the majority of starbursts the upsurge in star's births is triggered when two galaxies merge, or come too close to each other. The mutual attraction between the galaxies causes immense turmoil in the gas and dust, causing the sudden 'burst' in star formation. ESO PR Photo 43b/06 ESO PR Photo 43b/06 Larger View of NGC 1313

Guiding the Giant

NASA Astrophysics Data System (ADS)

1998-08-01

deliverable products is quite unprecedented, given the nature and scope of this project. This is a key ingredient for imaging surveys, the main goal of which is to provide target lists for 8-m class telescopes. EIS consists of two parts: a wide-angle survey ( "EIS-wide" ) and a deep, multi-colour survey in four optical and two infrared bands ( "EIS-deep" ). EIS-wide covers four pre-selected patches of sky (spanning the R.A. range from 22 h to 9 h ). The main science goals of EIS-wide include the search for distant clusters of galaxies and quasars. In addition, there are important spin-offs in terms of bright and distant galaxies, as well as new information about galactic structure and stellar populations. The observations were conducted in 10 runs in the period July 1997 - March 1998. A total of 36 nights were used for this part of the project. The images obtained cover a total area of 17 square degrees in the near-infrared I-band, reaching limiting magnitude of I ~ 23 and, furthermore, an area of 1.7 square degrees in the B- (blue), V- (green-yellow) and I-bands to a comparable depth. Altogether, the EIS data set consists of about 6000 science and calibration frames, totaling 96 Gbytes of raw data and over 200 Gbytes of reduced images and derived products. Some results from EIS ESO PR Photo 29/98 ESO PR Photo 29/98 [Preview - JPEG: 800 x 417 pix - 160k] [High-Res - JPEG: 3000 x 1562 pix - 1.2Mb] This photo shows three views of a small field in the so-called EIS Patch-B . They were obtained during this survey in different colours: B - blue; V - green-yellow; I - near-infrared. At the centre is located a (candidate) cluster of galaxies at very large distance. This conclusion is based upon the different appearance of this cluster in the three frames: it is not seen in B; it is hardly visible in V and it is most obvious in I. This indicates that the galaxies in the cluster have very red colours. The effect is most likely due to high redshift (and therefore large distance) that

The Gaia-ESO Survey: A globular cluster escapee in the Galactic halo

NASA Astrophysics Data System (ADS)

Lind, K.; Koposov, S. E.; Battistini, C.; Marino, A. F.; Ruchti, G.; Serenelli, A.; Worley, C. C.; Alves-Brito, A.; Asplund, M.; Barklem, P. S.; Bensby, T.; Bergemann, M.; Blanco-Cuaresma, S.; Bragaglia, A.; Edvardsson, B.; Feltzing, S.; Gruyters, P.; Heiter, U.; Jofre, P.; Korn, A. J.; Nordlander, T.; Ryde, N.; Soubiran, C.; Gilmore, G.; Randich, S.; Ferguson, A. M. N.; Jeffries, R. D.; Vallenari, A.; Allende Prieto, C.; Pancino, E.; Recio-Blanco, A.; Romano, D.; Smiljanic, R.; Bellazzini, M.; Damiani, F.; Hill, V.; de Laverny, P.; Jackson, R. J.; Lardo, C.; Zaggia, S.

2015-03-01

A small fraction of the halo field is made up of stars that share the light element (Z ≤ 13) anomalies characteristic of second generation globular cluster (GC) stars. The ejected stars shed light on the formation of the Galactic halo by tracing the dynamical history of the clusters, which are believed to have once been more massive. Some of these ejected stars are expected to show strong Al enhancement at the expense of shortage of Mg, but until now no such star has been found. We search for outliers in the Mg and Al abundances of the few hundreds of halo field stars observed in the first eighteen months of the Gaia-ESO public spectroscopic survey. One halo star at the base of the red giant branch, here referred to as 22593757-4648029 is found to have [ Mg/Fe ] = -0.36 ± 0.04 and [ Al/Fe ] = 0.99 ± 0.08, which is compatible with the most extreme ratios detected in GCs so far. We compare the orbit of 22593757-4648029 to GCs of similar metallicity andfind it unlikely that this star has been tidally stripped with low ejection velocity from any of the clusters. However, both chemical and kinematic arguments render it plausible that the star has been ejected at high velocity from the anomalous GC ω Centauri within the last few billion years. We cannot rule out other progenitor GCs, because some may have disrupted fully, and the abundance and orbital data are inadequate for many of those that are still intact. Based on data acquired by the Gaia-ESO Survey, programme ID 188.B-3002. Observations were made with ESO Telescopes at the La Silla Paranal Observatory.Appendix A is available in electronic form at http://www.aanda.org

PrP(C) homodimerization stimulates the production of PrPC cleaved fragments PrPN1 and PrPC1.

PubMed

Béland, Maxime; Motard, Julie; Barbarin, Alice; Roucou, Xavier

2012-09-19

An endoproteolytic cleavage termed α-cleavage between residues 111/112 is a characteristic feature of the cellular prion protein (PrP(C)). This cleavage generates a soluble N-terminal fragment (PrPN1) and a glycosylphosphatidylinositol-anchored C-terminal fragment (PrPC1). Independent studies demonstrate that modulating PrP(C) α-cleavage represents a potential therapeutic strategy in prion diseases. The regulation of PrP(C) α-cleavage is unclear. The only known domain that is essential for the α-cleavage to occur is a hydrophobic domain (HD). Importantly, the HD is also essential for the formation of PrP(C) homodimers. To explore the role of PrP(C) homodimerization on the α-cleavage, we used a well described inducible dimerization strategy whereby a chimeric PrP(C) composed of a modified FK506-binding protein (Fv) fused with PrP(C) and termed Fv-PrP is incubated in the presence of a dimerizer AP20187 ligand. We show that homodimerization leads to a considerable increase of PrP(C) α-cleavage in cultured cells and release of PrPN1 and PrPC1. Interestingly, enforced homodimerization increased PrP(C) levels at the plasma membrane, and preventing PrP(C) trafficking to the cell surface inhibited dimerization-induced α-cleavage. These observations were confirmed in primary hippocampal neurons from transgenic mice expressing Fv-PrP. The proteases responsible for the α-cleavage are still elusive, and in contrast to initial studies we confirm more recent investigations that neither ADAM10 nor ADAM17 are involved. Importantly, PrPN1 produced after PrP(C) homodimerization protects against toxic amyloid-β (Aβ) oligomers. Thus, our results show that PrP(C) homodimerization is an important regulator of PrP(C) α-cleavage and may represent a potential therapeutic avenue against Aβ toxicity in Alzheimer's disease.

ESO-Hα 574 and Par-Lup 3-4 jets: Exploring the spectral, kinematical, and physical properties

NASA Astrophysics Data System (ADS)

Whelan, E. T.; Bonito, R.; Antoniucci, S.; Alcalá, J. M.; Giannini, T.; Nisini, B.; Bacciotti, F.; Podio, L.; Stelzer, B.; Comerón, F.

2014-05-01

In this paper a comprehensive analysis of VLT/X-Shooter observations of two jet systems, namely ESO-Hα 574 a K8 classical T Tauri star and Par-Lup 3-4 a very low mass (0.13 M⊙) M5 star, is presented. Both stars are known to have near-edge on accretion disks. A summary of these first X-shooter observations of jets was given in a 2011 letter. The new results outlined here include flux tables of identified emission lines, information on the morphology, kinematics and physical conditions of both jets and, updated estimates of Ṁout/Ṁacc. Asymmetries in the ESO-Hα 574 flow are investigated while the Par-Lup 3-4 jet is much more symmetric. The density, temperature, and therefore origin of the gas traced by the Balmer lines are investigated from the Balmer decrements and results suggest an origin in a jet for ESO-Hα 574 while for Par-Lup 3-4 the temperature and density are consistent with an accretion flow. Ṁacc is estimated from the luminosity of various accretion tracers. For both targets, new luminosity relationships and a re-evaluation of the effect of reddening and grey extinction (due to the edge-on disks) allows for substantial improvements on previous estimates of Ṁacc. It is found that log(Ṁacc) = -9.15 ± 0.45M⊙ yr-1 and -9.30 ± 0.27M⊙ yr-1 for ESO-Hα 574 and Par-Lup 3-4 respectively. Additionally, the physical conditions in the jets (electron density, electron temperature, and ionisation) are probed using various line ratios and compared with previous determinations from iron lines. The results are combined with the luminosity of the [SII]λ6731 line to derive Ṁout through a calculation of the gas emissivity based on a 5-level atom model. As this method for deriving Ṁout comes from an exact calculation based on the jet parameters (measured directly from the spectra) rather than as was done previously from an approximate formula based on the value of the critical density at an assumed unknown temperature, values of Ṁout are far more

Single-Molecule Imaging Reveals that Small Amyloid-β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC)

PubMed Central

Ganzinger, Kristina A; Narayan, Priyanka; Qamar, Seema S; Weimann, Laura; Ranasinghe, Rohan T; Aguzzi, Adriano; Dobson, Christopher M; McColl, James; St George-Hyslop, Peter; Klenerman, David

2014-01-01

Oligomers of the amyloid-β peptide (Aβ) play a central role in the pathogenesis of Alzheimer’s disease and have been suggested to induce neurotoxicity by binding to a plethora of cell-surface receptors. However, the heterogeneous mixtures of oligomers of varying sizes and conformations formed by Aβ42 have obscured the nature of the oligomeric species that bind to a given receptor. Here, we have used single-molecule imaging to characterize Aβ42 oligomers (oAβ42) and to confirm the controversial interaction of oAβ42 with the cellular prion protein (PrPC) on live neuronal cells. Our results show that, at nanomolar concentrations, oAβ42 interacts with PrPC and that the species bound to PrPC are predominantly small oligomers (dimers and trimers). Single-molecule biophysical studies can thus aid in deciphering the mechanisms that underlie receptor-mediated oAβ-induced neurotoxicity, and ultimately facilitate the discovery of novel inhibitors of these pathways. PMID:25294384

Into the Epoch of Galaxy Formation

NASA Astrophysics Data System (ADS)

2000-02-01

first of the four 8.2-m VLT Unit Telescopes. A first analysis of the new observations indicates that "evolved" galaxies were already present when the Universe was only 4 billion years old. This information is of great importance to our understanding of how the matter in the early Universe condensed and the first galaxies and stars came into being. While in the nearby Universe evolved galaxies are preferentially located in denser environments such as groups and clusters of galaxies, little is currently known about the distribution in space of such objects at early cosmic epochs. In order to be able to see such obscured and/or "evolved" galaxies in the early Universe, and to look for hitherto unknown galaxies beyond the limits of "deep-field" imaging in visible spectral bands, it is necessary to employ other observing techniques. The astronomers must search for such objects on large-field, very long-exposure sky images obtained in the near-infrared (NIR, wavelength 1-2 µm) region of the electromagnetic spectrum and at even longer wavelengths (> 10 µm) in the far-IR and in the sub-mm range. Such observations are beyond the capability of the infrared cameras installed on the world's 4-m class telescopes. However, the advent of the ISAAC instrument at the 8.2-m ANTU telescope has now opened new and exciting research opportunities in this direction for European astronomers. With ISAAC , it is possible to obtain "deep" NIR images in an unprecedentedly wide field of view, covering a sky area about 7 times larger than with the best instruments previously available on very large telescopes. Such observations also benefit greatly from the very good optical quality provided by the active optics control of the VLT, as well as the excellent Paranal site. The ISAAC/ANTU observations ESO PR Photo 06a/00 ESO PR Photo 06a/00 [Preview - JPEG: 400 x 427pix - 69k] [Normal - JPEG: 800 x 853 pix - 195k] [Full-Res - JPEG: 942 x 1004 pix - 635k] Caption : ESO PR Photo 06a/00 displays a 4

Do 'Planemos' Have Progeny?

NASA Astrophysics Data System (ADS)

2006-06-01

at Austin. Two of the six turned out to have masses between five to 10 times that of Jupiter while two others are a tad heftier, at 10 to 15 times Jupiter's mass. All four of these objects are 'newborns', just a few million years old, and are located in star-forming regions about 450 light-years from Earth. The planemos show infrared emission from dusty discs that may evolve into miniature planetary systems over time. In another study, Subhanjoy Mohanty (Harvard-Smithsonian Center for Astrophysics, CfA), Ray Jayawardhana (Univ. of Toronto), Nuria Huelamo (ESO) and Eric Mamajek (also at CfA) used the Very Large Telescope, this time with its adaptive optics system and infrared camera NACO, to obtain images and spectra of a planetary mass companion discovered at ESO two years ago around a young brown dwarf that is itself about 25 times the mass of Jupiter. This planetary mass companion is the first-ever exoplanet to have been imaged (see ESO 12/05). ESO PR Photo 19b/06 ESO PR Photo 19b/06 The 2M1207 System The brown dwarf, dubbed 2M1207 for short and located 170 light-years from Earth, was known to be surrounded by a disc. Now, this team has found evidence for a disc around the eight-Jupiter-mass companion as well. "The pair probably formed together, like a petite stellar binary", explains lead author Mohanty, "instead of the companion forming in the disc around the brown dwarf, like a star-planet system." "Moreover", Jayawardhana adds, "it is quite likely that smaller planets or asteroids could now form in the disc around each one." Read more in the Appendix about recent developments on Exoplanets at ESO.

Light, Wind and Fire - Beautiful Image of a Cosmic Sculpture

NASA Astrophysics Data System (ADS)

2010-02-01

Today ESO has released a dramatic new image of NGC 346, the brightest star-forming region in our neighbouring galaxy, the Small Magellanic Cloud, 210 000 light-years away towards the constellation of Tucana (the Toucan). The light, wind and heat given off by massive stars have dispersed the glowing gas within and around this star cluster, forming a surrounding wispy nebular structure that looks like a cobweb. NGC 346, like other beautiful astronomical scenes, is a work in progress, and changes as the aeons pass. As yet more stars form from loose matter in the area, they will ignite, scattering leftover dust and gas, carving out great ripples and altering the face of this lustrous object. NGC 346 spans approximately 200 light-years, a region of space about fifty times the distance between the Sun and its nearest stellar neighbours. Astronomers classify NGC 346 as an open cluster of stars, indicating that this stellar brood all originated from the same collapsed cloud of matter. The associated nebula containing this clutch of bright stars is known as an emission nebula, meaning that gas within it has been heated up by stars until the gas emits its own light, just like the neon gas used in electric store signs. Many stars in NGC 346 are relatively young in cosmic terms with their births dating back only a few million years or so (eso0834). Powerful winds thrown off by a massive star set off this recent round of star birth by compressing large amounts of matter, the first critical step towards igniting new stars. This cloud of material then collapses under its own gravity, until some regions become dense and hot enough to roar forth as a brilliantly shining, nuclear fusion-powered furnace - a star, illuminating the residual debris of gas and dust. In sufficiently congested regions like NGC 346, with high levels of recent star birth, the result is a glorious, glowing vista for our telescopes to capture. NGC 346 is in the Small Magellanic Cloud, a dwarf galaxy some 210

Is this a Brown Dwarf or an Exoplanet?

NASA Astrophysics Data System (ADS)

2005-04-01

Since the discovery in 1995 of the first planet orbiting a normal star other than the Sun, there are now more than 150 candidates of these so-called exoplanets known. Most of them are detected by indirect methods, based either on variations of the radial velocity or the dimming of the star as the planet passes in front of it (see ESO PR 06/03, ESO PR 11/04 and ESO PR 22/04). Astronomers would, however, prefer to obtain a direct image of an exoplanet, allowing them to better characterize the object's physical nature. This is an exceedingly difficult task, as the planet is generally hidden in the "glare" of its host star. To partly overcome this problem, astronomers study very young objects. Indeed, sub-stellar objects are much hotter and brighter when young and therefore can be more easily detected than older objects of similar mass. Based on this approach, it might well be that last year's detection of a feeble speck of light next to the young brown dwarf 2M1207 by an international team of astronomers using the ESO Very Large Telescope (ESO PR 23/04) is the long-sought bona-fide image of an exoplanet. A recent report based on data from the Hubble Space Telescope seems to confirm this result. The even more recent observations made with the Spitzer Space Telescope of the warm infrared glows of two previously detected "hot Jupiter" planets is another interesting result in this context. This wealth of new results, obtained in the time span of a few months, illustrates perfectly the dynamic of this field of research. Tiny Companion ESO PR Photo 10a/05 ESO PR Photo 10a/05 The Sub-Stellar Companion to GQ Lupi (NACO/VLT) [Preview - JPEG: 400 x 429 pix - 22k] [Normal - JPEG: 800 x 875 pix - 132k] [Full Res - JPEG: 1042 x 1116 pix - 241k] Caption: ESO PR Photo 10a/05 shows the VLT NACO image, taken in the Ks-band, of GQ Lupi. The feeble point of light to the right of the star is the newly found cold companion. It is 250 times fainter than the star itself and it located 0

GIRAFFE Reaches towards the Stars

NASA Astrophysics Data System (ADS)

2002-07-01

"First Light" of New Powerful Spectrograph at the VLT Summary The first observations of stellar spectra have just been performed with the new GIRAFFE multi-object spectrograph on the ESO Very Large Telescope (VLT) at the Paranal Observatory in Chile. This milestone event was achieved in the early morning of July 3, 2002. It signifies another important step towards the full implementation of the extremely powerful Fibre Large Array Multi-Element Spectrograph (FLAMES) , one of the main instruments for the ESO VLT. This project is co-ordinated by ESO and incorporates many complex components that have been constructed at various research institutions in Europe and Australia. The GIRAFFE spectrograph provides unique possibilities for detailed observations of the properties of individual stars located in our Milky Way galaxy ( PR 16b/02 ) as well as in other galaxies of the Local Group. PR Photo 16a/02 : A series of stellar spectra recorded by GIRAFFE during "First Light" . PR Photo 16b/02 : Details of some of these stellar spectra . FLAMES and GIRAFFE ESO PR Photo 16a/02 ESO PR Photo 16a/02 [Preview - JPEG: 756 x 400 pix - 363k] [Normal - JPEG: 1511 x 800 pix - 1.2M] ESO PR Photo 16b/02 ESO PR Photo 16b/02 [Preview - JPEG: 461 x 400 pix - 196k] [Normal - JPEG: 921 x 800 pix - 606k] Caption : PR Photo 16a/02 : "First Light" test observation with the GIRAFFE spectrograph of about 50 high-quality spectra (10 min exposure at spectral resolution 7,000) of stars in the Milky Way disk, in the early morning of July 3, 2002. The stars have magnitudes of 12 - 16 and are all of solar type. The photo shows part of the image recorded with a 2000 x 4000 pixel CCD detector at the focal plane of the spectrograph. Each stellar spectrum is seen as one vertical line - some of the absorption lines can be seen as dark horizontal features. PR Photo 16b/02 shows a small part of this image. The three strong absorption lines that are visible as horizontal, dark lines in the lower part of the

Image digitising and analysis of outflows from young stars

NASA Astrophysics Data System (ADS)

Zealey, W. J.; Mader, S. L.

1997-08-01

We present IIIaJ, IIIaF and IVN band images of Herbig-Haro objects digitised from the ESO/SERC Southern Sky Survey plates. These form part of a digital image database of southern HH objects, which allows the identification of emission and reflection nebulosity and the location of the obscured sources of outflows.

Trio of Neptunes and their Belt

NASA Astrophysics Data System (ADS)

2006-05-01

a rocky/gas structure for the middle one. The outer planet has probably accreted some ice during its formation, and is likely to be made of a rocky/icy core surrounded by a quite massive envelope. Further calculations have also shown that the system is in a dynamically stable configuration. ESO PR Photo 18e/06 ESO PR Photo 18e/06 Formation Process of the Planetary System The outer planet also appears to be located near the inner edge of the habitable zone, where liquid water can exist at the surface of rocky/icy bodies. Although this planet is probably not Earth-like due to its heavy mass, its discovery opens the way to exciting perspectives. "This alone makes this system already exceptional", said Willy Benz, from Bern University, and co-author. "But the recent discovery by the Spitzer Space Telescope that the star most likely hosts an asteroid belt is adding the cherry to the cake." With three roughly equal-mass planets, one being in the habitable zone, and an asteroid belt, this planetary system shares many properties with our own solar system. "The planetary system around HD 69830 clearly represents a Rosetta stone in our understanding of how planets form", said Michel Mayor. "No doubt it will help us better understand the huge diversity we have observed since the first extra-solar planet was found 11 years ago." High resolution images and their captions are available on this page. Video footage and animations are also available on this page.

Lightest exoplanet yet discovered

NASA Astrophysics Data System (ADS)

2009-04-01

Well-known exoplanet researcher Michel Mayor today announced the discovery of the lightest exoplanet found so far. The planet, "e", in the famous system Gliese 581, is only about twice the mass of our Earth. The team also refined the orbit of the planet Gliese 581 d, first discovered in 2007, placing it well within the habitable zone, where liquid water oceans could exist. These amazing discoveries are the outcome of more than four years of observations using the most successful low-mass-exoplanet hunter in the world, the HARPS spectrograph attached to the 3.6-metre ESO telescope at La Silla, Chile. ESO PR Photo 15a/09 Artist's impression of Gliese 581 e ESO PR Photo 15b/09 A planet in the habitable zone ESO PR Video 15a/09 ESOcast 6 ESO PR Video 15b/09 VNR A-roll ESO PR Video 15c/09 Zoom-in on Gliese 581 e ESO PR Video 15d/09 Artist's impression of Gliese 581 e ESO PR Video 15e/09 Artist's impression of Gliese 581 d ESO PR Video 15f/09 Artist's impression of Gliese 581 system ESO PR Video 15g/09 The radial velocity method ESO PR Video 15h/09 Statement in English ESO PR Video 15i/09 Statement in French ESO PR Video 15j/09 La Silla Observatory "The holy grail of current exoplanet research is the detection of a rocky, Earth-like planet in the ‘habitable zone' -- a region around the host star with the right conditions for water to be liquid on a planet's surface", says Michel Mayor from the Geneva Observatory, who led the European team to this stunning breakthrough. Planet Gliese 581 e orbits its host star - located only 20.5 light-years away in the constellation Libra ("the Scales") -- in just 3.15 days. "With only 1.9 Earth-masses, it is the least massive exoplanet ever detected and is, very likely, a rocky planet", says co-author Xavier Bonfils from Grenoble Observatory. Being so close to its host star, the planet is not in the habitable zone. But another planet in this system appears to be. From previous observations -- also obtained with the HARPS spectrograph

Comet Tempel 1 Went Back to Sleep

NASA Astrophysics Data System (ADS)

2005-07-01

Astronomers Having Used ESO Telescopes Start Analysing Unique Dataset on the Comet Following the Deep Impact Mission Ten days after part of the Deep Impact spacecraft plunged onto Comet Tempel 1 with the aim to create a crater and expose pristine material from beneath the surface, astronomers are back in the ESO Offices in Santiago, after more than a week of observing at the ESO La Silla Paranal Observatory. In this unprecedented observing campaign - among the most ambitious ever conducted by a single observatory - the astronomers have collected a large amount of invaluable data on this comet. The astronomers have now started the lengthy process of data reduction and analysis. Being all together in a single place, and in close contacts with the space mission' scientific team, they will try to assemble a clear picture of the comet and of the impact. The ESO observations were part of a worldwide campaign to observe this unique experiment. During the campaign, ESO was connected by phone, email, and videoconference with colleagues in all major observatories worldwide, and data were freely exchanged between the different groups. This unique collaborative spirit provides astronomers with data taken almost around the clock during several days and this, with the largest variety of instruments, making the Deep Impact observing campaign one of the most successful of its kind, and thereby, ensuring the greatest scientific outcome. From the current analysis, it appears most likely that the impactor did not create a large new zone of activity and may have failed to liberate a large quantity of pristine material from beneath the surface. ESO PR Photo 22/05 ESO PR Photo 22/05 Evolution of Comet Tempel 1 (FORS2/VLT) [Preview - JPEG: 400 x 701 pix - 128k] [Normal - JPEG: 800 x 1401 pix - 357k] ESO PR Photo 22/05 Animated Gif Caption: ESO PR Photo 22/05 shows the evolution of Comet Tempel 1 as observed with the FORS2 instrument on Antu (VLT). The images obtained at the VLT show that

Surprise Discovery of Highly Developed Structure in the Young Universe

NASA Astrophysics Data System (ADS)

2005-03-01

ESO-VLT and ESA XMM-Newton Together Discover Earliest Massive Cluster of Galaxies Known Summary Combining observations with ESO's Very Large Telescope and ESA's XMM-Newton X-ray observatory, astronomers have discovered the most distant, very massive structure in the Universe known so far. It is a remote cluster of galaxies that is found to weigh as much as several thousand galaxies like our own Milky Way and is located no less than 9,000 million light-years away. The VLT images reveal that it contains reddish and elliptical, i.e. old, galaxies. Interestingly, the cluster itself appears to be in a very advanced state of development. It must therefore have formed when the Universe was less than one third of its present age. The discovery of such a complex and mature structure so early in the history of the Universe is highly surprising. Indeed, until recently it would even have been deemed impossible. PR Photo 05a/05: Discovery X-Ray Image of the Distant Cluster (ESA XMM-Netwon) PR Photo 05b/05: False Colour Image of XMMU J2235.3-2557 (FORS/VLT and ESA XMM-Newton) Serendipitous discovery ESO PR Photo 05a/05 ESO PR Photo 05a/05 Discovery X-Ray Image of the Distant Cluster (ESA XMM-Newton) [Preview - JPEG: 400 x 421 pix - 106k] [Normal - JPEG: 800 x 842 pix - 843k] [Full Res - JPEG: 2149 x 2262 pix - 2.5M] Caption: ESO PR Photo 05a/05 is a reproduction of the XMM-Newton observations of the nearby active galaxy NGC7314 (bright object in the centre) from which the newly found distant cluster (white box) was serendipitously identified. The circular field-of-view of XMM-Newton is half-a-degree in diameter, or about the same angular size as the Full Moon. The inset shows the diffuse X-ray emission from the distant cluster XMMU J2235.3-2557. Clusters of galaxies are gigantic structures containing hundreds to thousands of galaxies. They are the fundamental building blocks of the Universe and their study thus provides unique information about the underlying architecture of the

Report on the ESO Workshop ''Satellites and Streams in Santiago''

NASA Astrophysics Data System (ADS)

Küpper, A. H. W.; Mieske, S.

2015-09-01

Galactic satellites and tidal streams are arguably the two most direct imprints of hierarchical structure formation in the haloes of galaxies. At this ESO workshop we sought to create the big picture of the galactic accretion process, and shed light on the interplay between satellites and streams in the Milky Way, Andromeda and beyond. The Scientific Organising Committee prepared a well-balanced programme with 60 talks and 30 poster contributions, resulting in a meeting which was greatly enjoyed by the more than 110 participants at the venue, and worldwide via Twitter (#SSS15).

VLT Data Flow System Begins Operation

NASA Astrophysics Data System (ADS)

1999-06-01

Building a Terabyte Archive at the ESO Headquarters The ESO Very Large Telescope (VLT) is the sum of many sophisticated parts. The site at Cerro Paranal in the dry Atacama desert in Northern Chile is one of the best locations for astronomical observations from the surface of the Earth. Each of the four 8.2-m telescopes is a technological marvel with self-adjusting optics placed in a gigantic mechanical structure of the utmost precision, continuously controlled by advanced soft- and hardware. A multitude of extremely complex instruments with sensitive detectors capture the faint light from distant objects in the Universe and record the digital data fast and efficiently as images and spectra, with a minimum of induced noise. And now the next crucial link in this chain is in place. A few nights ago, following an extended test period, the VLT Data Flow System began providing the astronomers with a steady stream of high-quality, calibrated image and spectral data, ready to be interpreted. The VLT project has entered into a new phase with a larger degree of automation. Indeed, the first 8.2-m Unit Telescope, ANTU, with the FORS1 and ISAAC instruments, has now become a true astronomy machine . A smooth flow of data through the entire system ESO PR Photo 25a/99 ESO PR Photo 25a/99 [Preview - JPEG: 400 x 292 pix - 104k] [Normal - JPEG: 800 x 584 pix - 264k] [High-Res - JPEG: 3000 x 2189 pix - 1.5M] Caption to ESO PR Photo 25a/99 : Simplified flow diagramme for the VLT Data Flow System . It is a closed-loop software system which incorporates various subsystems that track the flow of data all the way from the submission of proposals to storage of the acquired data in the VLT Science Archive Facility. The DFS main components are: Program Handling, Observation Handling, Telescope Control System, Science Archive, Pipeline and Quality Control. Arrows indicate lines of feedback. Already from the start of this project more than ten years ago, the ESO Very Large Telescope was

Messages from the Abyss

NASA Astrophysics Data System (ADS)

2003-10-01

VLT Observes Infrared Flares from Black Hole at Galactic Centre [1] Summary An international team of astronomers led by researchers at the Max-Planck Institute for Extraterrestrial Physics (MPE) in Garching (Germany) [2] has discovered powerful infrared flares from the supermassive black hole at the heart of the Milky Way . The signals, rapidly flickering on a scale of minutes, must come from hot gas falling into the black hole, just before it disappears below the "event horizon" of the monster. The new observations strongly suggest that the Galactic Centre black hole rotates rapidly . Never before have scientists been able to study phenomena in the immediate neighbourhood of a black hole in such a detail. The new result is based on observations obtained with the NACO Adaptive Optics instrument on the 8.2-m VLT YEPUN telescope and is published in this week's edition of the research journal Nature. PR Photo 29a/03 : A powerful flare from the black hole at the galactic centre. PR Photo 29b/03 : Light curve of the flare . PR Video 01/03 : A powerful flare from the black hole at the galactic centre . Flashes of light from disappearing matter ESO PR Photo 29a/03 ESO PR Photo 29a/03 [Preview - JPEG: 650 x 400 pix - 118k [Normal - JPEG: 1300 x 800 pix - 370k] ESO PR Video Clip 01/03 [MPEG] ESO PR Video Clip 01/03 [MPEG Video; 29X k] Captions : PR Photo 29a/03 and PR Video Clip 01/03 show the detection of a powerful flare from the centre of the Milky Way galaxy. These and other adaptive optics (AO) images (with resolution 0.040 arcsec in the near-infrared H-band at wavelength 1.65 µm) of the central region of the Milky Way were obtained with the NACO imager on the 8.2-m VLT YEPUN telescope at the ESO Paranal Observatory on May 9, 2003. The image covers a sky area of about 1 x 1 arcsec, corresponding to about 45 light-days at the distance of the Galactic Centre. The time (in minutes from the beginning of the data set at 6h59m24s (UT) on May 9, 2003) is shown at the upper

Pattern recognition and expert image analysis systems in biomedical image processing (Invited Paper)

NASA Astrophysics Data System (ADS)

Oosterlinck, A.; Suetens, P.; Wu, Q.; Baird, M.; F. M., C.

1987-09-01

This paper gives an overview of pattern recoanition techniques (P.R.) used in biomedical image processing and problems related to the different P.R. solutions. Also the use of knowledge based systems to overcome P.R. difficulties, is described. This is illustrated by a common example ofabiomedical image processing application.

Portrait of a Dramatic Stellar Crib

NASA Astrophysics Data System (ADS)

2006-12-01

A new, stunning image of the cosmic spider, the Tarantula Nebula and its surroundings, finally pays tribute to this amazing, vast and intricately sculpted web of stars and gas. The newly released image, made with ESO's Wide Field Imager on the 2.2-m ESO/MPG Telescope at La Silla, covers 1 square degree on the sky and could therefore contain four times the full Moon. ESO PR Photo 50a/06 ESO PR Photo 50a/06 The Tarantula Nebula (WFI/2.2m) Known as the Tarantula Nebula for its spidery appearance, the 30 Doradus complex is a monstrous stellar factory. It is the largest emission nebula in the sky, and can be seen far down in the southern sky at a distance of about 170,000 light-years, in the southern constellation Dorado (The Swordfish or the Goldfish). It is part of one of the Milky Way's neighbouring galaxies, the Large Magellanic Cloud. The Tarantula Nebula is thought to contain more than half a million times the mass of the Sun in gas and this vast, blazing labyrinth hosts some of the most massive stars known. The nebula owes its name to the arrangement of its brightest patches of nebulosity, that somewhat resemble the legs of a spider. They extend from a central 'body' where a cluster of hot stars (designated 'R136') illuminates and shapes the nebula. This name, of the biggest spiders on the Earth, is also very fitting in view of the gigantic proportions of the celestial nebula - it measures nearly 1,000 light-years across and extends over more than one third of a degree: almost, but not quite, the size of the full Moon. If it were in our own Galaxy, at the distance of another stellar nursery, the Orion Nebula (1,500 light-years away), it would cover one quarter of the sky and even be visible in daylight. Because astronomers believe that most of the stars in the Universe were formed in large and hectic nurseries such as the 30 Doradus region, its study is fundamental. Early this year, astronomers took a new, wide look at the spider and its web of filaments, using

Successful "First Light" for VLT High-Resolution Spectrograph

NASA Astrophysics Data System (ADS)

1999-10-01

with UVES at KUEYEN was of SN 1987A , the famous supernova that exploded in the Large Magellanic Cloud (LMC) in February 1987, and the brightest supernova of the last 400 years. ESO PR Photo 37a/99 ESO PR Photo 37a/99 [Preview - JPEG: 400 x 455 pix - 87k] [Normal - JPEG: 645 x 733 pix - 166k] Caption to ESO PR Photo 37a/99 : This is a direct image of SN1987A, flanked by two nearby stars. The distance between these two is 4.5 arcsec. The slit (2.0 arcsec wide) through which the echelle spectrum shown in PR Photo 37b/99 was obtained, is outlined. This reproduction is from a 2-min exposure through a R(ed) filter with the FORS1 multi-mode instrument at VLT ANTU, obtained in 0.55 arcsec seeing on September 20, 1998. North is up and East is left. ESO PR Photo 37b/99 ESO PR Photo 37b/99 [Preview - JPEG: 400 x 459 pix - 130k] [Normal - JPEG: 800 x 917 pix - 470k] [High-Res - JPEG: 3000 x 3439 pix - 6.5M] Caption to ESO PR Photo 37b/99 : This shows the raw image, as read from the CCD, with the recorded echelle spectrum of SN1987A. With this technique, the supernova spectrum is divided into many individual parts ( spectral orders , each of which appears as a narrow horizontal line) that together cover the wavelength interval from 479 to 682 nm (from the bottom to the top), i.e. from blue to red light. Many bright emission lines from different elements are visible, e.g. the strong H-alpha line from hydrogen near the centre of the fourth order from the top. Emission lines from the terrestrial atmosphere are seen as vertical bright lines that cover the full width of the individual horizontal bands. Since this exposure was done with the nearly Full Moon above the horizon, an underlying, faint absorption-line spectrum of reflected sunlight is also visible. The exposure time was 30 min and the seeing conditions were excellent (0.5 arcsec). ESO PR Photo 37c/99 ESO PR Photo 37c/99 [Preview - JPEG: 400 x 355 pix - 156k] [Normal - JPEG: 800 x 709 pix - 498k] [High-Res - JPEG: 1074 x 952

World's fastest and most sensitive astronomical camera

NASA Astrophysics Data System (ADS)

2009-06-01

The next generation of instruments for ground-based telescopes took a leap forward with the development of a new ultra-fast camera that can take 1500 finely exposed images per second even when observing extremely faint objects. The first 240x240 pixel images with the world's fastest high precision faint light camera were obtained through a collaborative effort between ESO and three French laboratories from the French Centre National de la Recherche Scientifique/Institut National des Sciences de l'Univers (CNRS/INSU). Cameras such as this are key components of the next generation of adaptive optics instruments of Europe's ground-based astronomy flagship facility, the ESO Very Large Telescope (VLT). ESO PR Photo 22a/09 The CCD220 detector ESO PR Photo 22b/09 The OCam camera ESO PR Video 22a/09 OCam images "The performance of this breakthrough camera is without an equivalent anywhere in the world. The camera will enable great leaps forward in many areas of the study of the Universe," says Norbert Hubin, head of the Adaptive Optics department at ESO. OCam will be part of the second-generation VLT instrument SPHERE. To be installed in 2011, SPHERE will take images of giant exoplanets orbiting nearby stars. A fast camera such as this is needed as an essential component for the modern adaptive optics instruments used on the largest ground-based telescopes. Telescopes on the ground suffer from the blurring effect induced by atmospheric turbulence. This turbulence causes the stars to twinkle in a way that delights poets, but frustrates astronomers, since it blurs the finest details of the images. Adaptive optics techniques overcome this major drawback, so that ground-based telescopes can produce images that are as sharp as if taken from space. Adaptive optics is based on real-time corrections computed from images obtained by a special camera working at very high speeds. Nowadays, this means many hundreds of times each second. The new generation instruments require these

MOSE: A Demonstrator for an Automatic Operational System for the Optical Turbulence Forecast for ESO Sites

NASA Astrophysics Data System (ADS)

Masciadri, Elena; Lascaux, F.; Turchi, A.; Fini, L.

2017-09-01

"Most of the observations performed with new-generation ground-based telescopes are employing the Service Mode. To optimize the flexible-scheduling of scientific programs and instruments, the optical turbulence (OT) forecast is a must, particularly when observations are supported by adaptive optics (AO) and Interferometry. Reliable OT forecast are crucial to optimize the usage of AO and interferometric facilities which is not possible when using only optical measurements. Numerical techniques are the best placed to achieve such a goal. The MOSE project (MOdeling ESO Sites), co-funded by ESO, aimed at proving the feasibility of the forecast of (1) all the classical atmospheric parameters (such as temperature, wind speed and direction, relative humidity) and (2) the optical turbulence i.e. the CN 2 profiles and all the main integrated astro-climatic parameters derived from the CN 2 (the seeing, the isoplanatic angle, the wavefront coherence time) above the two ESO sites of Cerro Paranal and Cerro Armazones. The proposed technique is based on the use of a non-hydrostatic atmospheric meso-scale model and a dedicated code for the optical turbulence. The final goal of the project aimed at implementing an automatic system for the operational forecasts of the aforementioned parameters to support the astronomical observations above the two sites. MOSE Phase A and B have been completed and a set of dedicated papers have been published on the topic. Model performances have been extensively quantified with several dedicated figures of merit and we proved that our tool is able to provide reliable forecasts of optical turbulence and atmospheric parameters with very satisfactory score of success. This should guarantee us to make a step ahead in the framework of the Service Mode of new generation telescopes. A conceptual design as well as an operational plan of the automatic system has been submitted to ESO as integral part of the feasibility study. We completed a negotiation with

The Gaia-ESO Survey. Mg-Al anti-correlation in iDR4 globular clusters

NASA Astrophysics Data System (ADS)

Pancino, E.; Romano, D.; Tang, B.; Tautvaišienė, G.; Casey, A. R.; Gruyters, P.; Geisler, D.; San Roman, I.; Randich, S.; Alfaro, E. J.; Bragaglia, A.; Flaccomio, E.; Korn, A. J.; Recio-Blanco, A.; Smiljanic, R.; Carraro, G.; Bayo, A.; Costado, M. T.; Damiani, F.; Jofré, P.; Lardo, C.; de Laverny, P.; Monaco, L.; Morbidelli, L.; Sbordone, L.; Sousa, S. G.; Villanova, S.

2017-05-01

We use Gaia-ESO (GES) Survey iDR4 data to explore the Mg-Al anti-correlation in globular clusters that were observed as calibrators, as a demonstration of the quality of Gaia-ESO Survey data and analysis. The results compare well with the available literature, within 0.1 dex or less, after a small (compared to the internal spreads) offset between the UVES and GIRAFFE data of 0.10-0.15 dex was taken into account. In particular, for the first time we present data for NGC 5927, which is one of the most metal-rich globular clusters studied in the literature so far with [ Fe / H ] = - 0.39 ± 0.04 dex; this cluster was included to connect with the open cluster regime in the Gaia-ESO Survey internal calibration. The extent and shape of the Mg-Al anti-correlation provide strong constraints on the multiple population phenomenon in globular clusters. In particular, we studied the dependency of the Mg-Al anti-correlation extension with metallicity, present-day mass,and age of the clusters, using GES data in combination with a large set of homogenized literature measurements.We find a dependency with both metallicity and mass, which is evident when fitting for the two parameters simultaneously, but we do not find significant dependency with age. We confirm that the Mg-Al anti-correlation is not seen in all clusters, but disappears for the less massive or most metal-rich clusters. We also use our data set to see whether a normal anti-correlation would explain the low [Mg/α] observed in some extragalactic globular clusters, but find that none of the clusters in our sample can reproduce it; a more extreme chemical composition, such as that of NGC 2419, would be required. We conclude that GES iDR4 data already meet the requirements set by the main survey goals and can be used to study globular clusters in detail, even if the analysis procedures were not specifically designed for them. Based on data products from observations made with ESO Telescopes at the La Silla Paranal

Double Planet Meets Triple Star

NASA Astrophysics Data System (ADS)

2002-08-01

American astronomers Steve W. McDonald and James L. Elliot (Massachussetts Institute of Technology [MIT], Cambridge, USA). Further refinements provided by other observers later showed that the first event would be visible from South America on July 20, 2002 , while a second one on August 21 was expected to be observable in the Pacific basin, from the western coast of North America down to Hawaii and New Zealand. A stellar occultation provides a useful opportunity to study the planetary atmosphere, by means of accurate photometric measurements of the dimming of the stellar light, as the planet moves in front of the star. The observed variation of the light intensity and colour provides crucial information about the structure (atmospheric layers) and composition of different gases and aerosols. More information is available in the Appendix below. The July 20 occultation ESO PR Photo 21a/02 ESO PR Photo 21a/02 [Preview - JPEG: 400 x 477 pix - 65k] [Normal - JPEG: 800 x 953 pix - 224k] Caption : PR Photo 21c/02 shows the path of Pluto's shadow (grey region) during the July 20, 2002 occultation. The shadow has a diameter of about 2300 km and moves from right to left; the timings along the central line are indicated in one-minute intervals (Universal Time - UT). The width of the gray area corresponds to the regions where more than 50% of the light from the star P126 A was attenuated by Pluto's atmosphere. The dotted lines indicate where the stellar flux was attenuated by more than 10%. The maximum duration of the occultation (for observers located at the middle of the shadow track) was about 3 min. The plot is based on astrometric measurements posted at the MIT site. Once completely analyzed, the VLT NACO images will provide significantly better accuracy on the location of this track and therefore a solid basis for the interpretation of the photometric observations obtained with other telescopes. In order to profit from the rare opportunity to learn more about Pluto and its

"First Light" for the VLT Interferometer

NASA Astrophysics Data System (ADS)

2001-03-01

VLTI . It was first envisaged in the early 1980's and has been continuously updated, as new technologies and materials became available during the intervening period. The present series of functional tests will go on for some time and involve many different configurations of the small telescopes and the instrument. It is then expected that the first combination of light beams from two of the VLT 8.2-m telescopes will take place in late 2001 . According to current plans, regular science observations will start from 2002, when the European and international astronomical community will have access to the full interferometric facility and the specially developed VLTI instrumentation now under construction. A wide range of scientific investigations will then become possible, from the search for planets around nearby stars, to the study of energetic processes at the cores of distant galaxies. With its superior angular resolution (image sharpness), the VLT is now beginning to open a new era in observational optical and infrared astronomy. The ambition of ESO is to make this type of observations available to all astronomers, not just the interferometry specialists. Video Clip 03/01 : Various video scenes related to the VLTI and the "First Fringes". PR Photo 10a/01 : "First Fringes" from the VLTI on the computer screen. PR Photo 10b/01 : Celebrating the VLTI "First Fringes" . PR Photo 10c/01 : Overview of the VLT Interferometer . PR Photo 10d/01 : Interferometric observations: Fringes from two stars of different angular size . PR Photo 10e/01 : Interferometric observations: Change of fringes with increasing baseline . PR Photo 10f/01 : Aerial view of the installations for the VLTI on the Paranal platform. PR Photo 10g/01 : Stations for the VLTI Auxiliary Telescopes. PR Photo 10h/01 : A test siderostat in place for observations. PR Photo 10i/01 : A test siderostat ( close-up ). PR Photo 10j/01 : One of the Delay Line carriages in the Interferometric Tunnel. PR Photo 10k/01 : The

Lucky Imaging in Astronomy

NASA Astrophysics Data System (ADS)

Brandner, Wolfgang; Hormuth, Felix

Lucky Imaging improves the angular resolution of astronomical observations hampered by atmospheric turbulence ("seeing"). Unlike adaptive optics, Lucky Imaging is a passive observing technique with individual integration times comparable to the atmospheric coherence time. Thanks to the advent of essentially noise free "Electron multiplying CCD" detectors, Lucky Imaging saw a renewed interest in the past decade. It is now routinely used at a number of 2-5-m class telescopes, such as ESO's NTT. We review the history of Lucky Imaging, present the technical implementation, describe the data analysis philosophy, and show some recent results obtained with this technique. We also discuss the advantages and limitations of Lucky Imaging compared to other passive and active high angular resolution observing techniques.

Surfing a Black Hole

NASA Astrophysics Data System (ADS)

2002-10-01

Star Orbiting Massive Milky Way Centre Approaches to within 17 Light-Hours [1] Summary An international team of astronomers [2], lead by researchers at the Max-Planck Institute for Extraterrestrial Physics (MPE) , has directly observed an otherwise normal star orbiting the supermassive black hole at the center of the Milky Way Galaxy. Ten years of painstaking measurements have been crowned by a series of unique images obtained by the Adaptive Optics (AO) NAOS-CONICA (NACO) instrument [3] on the 8.2-m VLT YEPUN telescope at the ESO Paranal Observatory. It turns out that earlier this year the star approached the central Black Hole to within 17 light-hours - only three times the distance between the Sun and planet Pluto - while travelling at no less than 5000 km/sec . Previous measurements of the velocities of stars near the center of the Milky Way and variable X-ray emission from this area have provided the strongest evidence so far of the existence of a central Black Hole in our home galaxy and, implicitly, that the dark mass concentrations seen in many nuclei of other galaxies probably are also supermassive black holes. However, it has not yet been possible to exclude several alternative configurations. In a break-through paper appearing in the research journal Nature on October 17th, 2002, the present team reports their exciting results, including high-resolution images that allow tracing two-thirds of the orbit of a star designated "S2" . It is currently the closest observable star to the compact radio source and massive black hole candidate "SgrA*" ("Sagittarius A") at the very center of the Milky Way. The orbital period is just over 15 years. The new measurements exclude with high confidence that the central dark mass consists of a cluster of unusual stars or elementary particles, and leave little doubt of the presence of a supermassive black hole at the centre of the galaxy in which we live . PR Photo 23a/02 : NACO image of the central region of the Milky Way

A Glimpse of the Very Early Universal Web

NASA Astrophysics Data System (ADS)

2001-05-01

matter of days only. This has made it possible to predict what the universe might look like when it was still young. And working the opposite way, a comparison between the computer models and the real world might then provide some information about the initial conditions. Unfortunately, until recently astronomical telescopes were not sufficiently powerful to directly study the "real world" of the young universe by observing in detail the extremely faint objects at that early epoch, and thereby to test the predictions. Now, however, the advent of giant telescopes of the 8-10 metre class has changed this situation and a group of astronomers has used the ESO Very Large Telescope (VLT) at Paranal Observatory (Chile) to view a small part of the early cosmic structure. The telescopes have begun to catch up with the computer simulations. First Structures of the Universe ESO PR Photo 19a/01 ESO PR Photo 19a/01 [Preview - JPEG: 353 x 400 pix - 304k] [Normal - JPEG: 706 x 800 pix - 952k] Caption : Computer model of the universe at an age of about 2 billion years (i.e., at redshift 3, see the text). In the simulated universe gravity causes the primordial matter to arrange itself in thin filaments, much like a spider's web. The colour coding indicates the density of the gas, yellow for highest, red for medium, and blue for the lowest density. In the high density (yellow) regions the gas will undergo collapse and ignite bursts of star formation. Those small star-forming regions will slowly stream along the filaments. When they meet at the intersections (the "nodes"), they will merge and cause a gradual build-up of the galaxies we know today. In this sense they are the building blocks of which galaxies are made. This simulated image was computed by Tom Theuns at the Max-Planck-Institute for Astrophysics, Garching, Germany, and kindly made available for this Press Release (please be sure to quote the source). All recent computer-simulations of the early universe have one prediction in

PESSTO: survey description and products from the first data release by the Public ESO Spectroscopic Survey of Transient Objects

NASA Astrophysics Data System (ADS)

Smartt, S. J.; Valenti, S.; Fraser, M.; Inserra, C.; Young, D. R.; Sullivan, M.; Pastorello, A.; Benetti, S.; Gal-Yam, A.; Knapic, C.; Molinaro, M.; Smareglia, R.; Smith, K. W.; Taubenberger, S.; Yaron, O.; Anderson, J. P.; Ashall, C.; Balland, C.; Baltay, C.; Barbarino, C.; Bauer, F. E.; Baumont, S.; Bersier, D.; Blagorodnova, N.; Bongard, S.; Botticella, M. T.; Bufano, F.; Bulla, M.; Cappellaro, E.; Campbell, H.; Cellier-Holzem, F.; Chen, T.-W.; Childress, M. J.; Clocchiatti, A.; Contreras, C.; Dall'Ora, M.; Danziger, J.; de Jaeger, T.; De Cia, A.; Della Valle, M.; Dennefeld, M.; Elias-Rosa, N.; Elman, N.; Feindt, U.; Fleury, M.; Gall, E.; Gonzalez-Gaitan, S.; Galbany, L.; Morales Garoffolo, A.; Greggio, L.; Guillou, L. L.; Hachinger, S.; Hadjiyska, E.; Hage, P. E.; Hillebrandt, W.; Hodgkin, S.; Hsiao, E. Y.; James, P. A.; Jerkstrand, A.; Kangas, T.; Kankare, E.; Kotak, R.; Kromer, M.; Kuncarayakti, H.; Leloudas, G.; Lundqvist, P.; Lyman, J. D.; Hook, I. M.; Maguire, K.; Manulis, I.; Margheim, S. J.; Mattila, S.; Maund, J. R.; Mazzali, P. A.; McCrum, M.; McKinnon, R.; Moreno-Raya, M. E.; Nicholl, M.; Nugent, P.; Pain, R.; Pignata, G.; Phillips, M. M.; Polshaw, J.; Pumo, M. L.; Rabinowitz, D.; Reilly, E.; Romero-Cañizales, C.; Scalzo, R.; Schmidt, B.; Schulze, S.; Sim, S.; Sollerman, J.; Taddia, F.; Tartaglia, L.; Terreran, G.; Tomasella, L.; Turatto, M.; Walker, E.; Walton, N. A.; Wyrzykowski, L.; Yuan, F.; Zampieri, L.

2015-07-01

Context. The Public European Southern Observatory Spectroscopic Survey of Transient Objects (PESSTO) began as a public spectroscopic survey in April 2012. PESSTO classifies transients from publicly available sources and wide-field surveys, and selects science targets for detailed spectroscopic and photometric follow-up. PESSTO runs for nine months of the year, January - April and August - December inclusive, and typically has allocations of 10 nights per month. Aims: We describe the data reduction strategy and data products that are publicly available through the ESO archive as the Spectroscopic Survey data release 1 (SSDR1). Methods: PESSTO uses the New Technology Telescope with the instruments EFOSC2 and SOFI to provide optical and NIR spectroscopy and imaging. We target supernovae and optical transients brighter than 20.5m for classification. Science targets are selected for follow-up based on the PESSTO science goal of extending knowledge of the extremes of the supernova population. We use standard EFOSC2 set-ups providing spectra with resolutions of 13-18 Å between 3345-9995 Å. A subset of the brighter science targets are selected for SOFI spectroscopy with the blue and red grisms (0.935-2.53 μm and resolutions 23-33 Å) and imaging with broadband JHKs filters. Results: This first data release (SSDR1) contains flux calibrated spectra from the first year (April 2012-2013). A total of 221 confirmed supernovae were classified, and we released calibrated optical spectra and classifications publicly within 24 h of the data being taken (via WISeREP). The data in SSDR1 replace those released spectra. They have more reliable and quantifiable flux calibrations, correction for telluric absorption, and are made available in standard ESO Phase 3 formats. We estimate the absolute accuracy of the flux calibrations for EFOSC2 across the whole survey in SSDR1 to be typically ~15%, although a number of spectra will have less reliable absolute flux calibration because of

Electroactive Shape Memory Property of a Cu-decorated CNT Dispersed PLA/ESO Nanocomposite

PubMed Central

Alam, Javed; Khan, Aslam; Alam, Manawwer; Mohan, Raja

2015-01-01

Shape memory polymer (SMP) nanocomposites with a fast electro-actuation speed were prepared by dispersing Cu-decorated carbon nanotubes (CNTs) (Cu-CNTs, 1 wt %, 2 wt %, and 3 wt %) in a polylactic acid (PLA)/epoxidized soybean oil (ESO) blend matrix. The shape memory effect (SME) induced by an electrical current was investigated by a fold-deploy “U”-shape bending test. In addition, the Cu-CNT dispersed PLA/ESO nanocomposite was characterized by atomic force microscopy (AFM), dynamic mechanical analysis (DMA) and tensile and electrical measurements. The results demonstrated that the SME was dependent on the Cu-CNT content in the nanocomposites. When comparing the SMEs of the nanocomposite specimens with different Cu-CNT contents, the 2 wt % Cu-CNT dispersed system exhibited a shape recovery as high as 98% within 35 s due to its higher electrical conductivity that results from uniform Cu-CNT dispersion. However, the nanocomposites that contained 1 wt % and 3 wt % Cu-CNTs required 75 s and 63 s, respectively, to reach a maximum recovery level. In addition, the specimens exhibited better mechanical properties after the addition of Cu-CNTs. PMID:28793570

TCS and peripheral robotization and upgrade on the ESO 1-meter telescope at La Silla Observatory

NASA Astrophysics Data System (ADS)

Ropert, S.; Suc, V.; Jordán, A.; Tala, M.; Liedtke, P.; Royo, S.

2016-07-01

In this work we describe the robotization and upgrade of the ESO 1m telescope located at La Silla Observatory. The ESO 1m telescope was the first telescope installed in La Silla, in 1966. It now hosts as a main instrument the FIber Dual EchellE Optical Spectrograph (FIDEOS), a high resolution spectrograph designed for precise Radial Velocity (RV) measurements on bright stars. In order to meet this project's requirements, the Telescope Control System (TCS) and some of its mechanical peripherals needed to be upgraded. The TCS was also upgraded into a modern and robust software running on a group of single board computers interacting together as a network with the CoolObs TCS developed by ObsTech. One of the particularities of the CoolObs TCS is that it allows to fuse the input signals of 2 encoders per axis in order to achieve high precision and resolution of the tracking with moderate cost encoders. One encoder is installed on axis at the telescope and the other on axis at the motor. The TCS was also integrated with the FIDEOS instrument system so that all the system can be controlled through the same remote user interface. Our modern TCS unit allows the user to run observations remotely through a secured internet web interface, minimizing the need of an on-site observer and opening a new age in robotic astronomy for the ESO 1m telescope.

Supernova rates from the Southern inTermediate Redshift ESO Supernova Search (STRESS)

NASA Astrophysics Data System (ADS)

Botticella, M. T.; Riello, M.; Cappellaro, E.; Benetti, S.; Altavilla, G.; Pastorello, A.; Turatto, M.; Greggio, L.; Patat, F.; Valenti, S.; Zampieri, L.; Harutyunyan, A.; Pignata, G.; Taubenberger, S.

2008-02-01

Aims:To measure the supernova (SN) rates at intermediate redshift we performed a search, the Southern inTermediate Redshift ESO Supernova Search (STRESS). Unlike most of the current high redshift SN searches, this survey was specifically designed to estimate the rate for both type Ia and core collapse (CC) SNe. Methods: We counted the SNe discovered in a selected galaxy sample measuring SN rate per unit blue band luminosity. Our analysis is based on a sample of 43 000 galaxies and on 25 spectroscopically confirmed SNe plus 64 selected SN candidates. Our approach is aimed at obtaining a direct comparison of the high redshift and local rates and at investigating the dependence of the rates on specific galaxy properties, most notably their colour. Results: The type Ia SN rate, at mean redshift z=0.3, is 0.22+0.10 +0.16-0.08 -0.14 h702 SNu, while the CC SN rate, at z=0.21, is 0.82+0.31 +0.30-0.24 -0.26 h702 SNu. The quoted errors are the statistical and systematic uncertainties. Conclusions: With respect to the local value, the CC SN rate at z=0.2 is higher by a factor of 2, whereas the type Ia SN rate remains almost constant. This implies that a significant fraction of SN Ia progenitors has a lifetime longer than 2{-}3 Gyr. We also measured the SN rates in the red and blue galaxies and found that the SN Ia rate seems to be constant in galaxies of different colour, whereas the CC SN rate seems to peak in blue galaxies, as in the local Universe. SN rates per unit volume were found to be consistent with other measurements showing a steeper evolution with redshift for CC SNe than SNe Ia. We have exploited the link between SFH and SN rates to predict the evolutionary behaviour of the SN rates and compare it with the path indicated by observations. We conclude that in order to constrain the mass range of CC SN progenitors and SN Ia progenitor models it is necessary to reduce the uncertainties in the cosmic SFH. In addition it is important to apply a consistent dust

The AMBRE Project: Stellar parameterisation of the ESO:FEROS archived spectra

NASA Astrophysics Data System (ADS)

Worley, C. C.; de Laverny, P.; Recio-Blanco, A.; Hill, V.; Bijaoui, A.; Ordenovic, C.

2012-06-01

Context. The AMBRE Project is a collaboration between the European Southern Observatory (ESO) and the Observatoire de la Côte d'Azur (OCA) that has been established in order to carry out the determination of stellar atmospheric parameters for the archived spectra of four ESO spectrographs. Aims: The analysis of the FEROS archived spectra for their stellar parameters (effective temperatures, surface gravities, global metallicities, alpha element to iron ratios and radial velocities) has been completed in the first phase of the AMBRE Project. From the complete ESO:FEROS archive dataset that was received, a total of 21 551 scientific spectra have been identified, covering the period 2005 to 2010. These spectra correspond to 6285 stars. Methods: The determination of the stellar parameters was carried out using the stellar parameterisation algorithm, MATISSE (MATrix Inversion for Spectral SynthEsis), which has been developed at OCA to be used in the analysis of large scale spectroscopic studies in galactic archaeology. An analysis pipeline has been constructed that integrates spectral normalisation, cleaning and radial velocity correction procedures in order that the FEROS spectra could be analysed automatically with MATISSE to obtain the stellar parameters. The synthetic grid against which the MATISSE analysis is carried out is currently constrained to parameters of FGKM stars only. Results: Stellar atmospheric parameters, effective temperature, surface gravity, metallicity and alpha element abundances, were determined for 6508 (30.2%) of the FEROS archived spectra (~3087 stars). Radial velocities were determined for 11 963 (56%) of the archived spectra. 2370 (11%) spectra could not be analysed within the pipeline due to very low signal-to-noise ratios or missing spectral orders. 12 673 spectra (58.8%) were analysed in the pipeline but their parameters were discarded based on quality criteria and error analysis determined within the automated process. The majority of

The Gaia-ESO Survey: Probes of the inner disk abundance gradient

NASA Astrophysics Data System (ADS)

Jacobson, H. R.; Friel, E. D.; Jílková, L.; Magrini, L.; Bragaglia, A.; Vallenari, A.; Tosi, M.; Randich, S.; Donati, P.; Cantat-Gaudin, T.; Sordo, R.; Smiljanic, R.; Overbeek, J. C.; Carraro, G.; Tautvaišienė, G.; San Roman, I.; Villanova, S.; Geisler, D.; Muñoz, C.; Jiménez-Esteban, F.; Tang, B.; Gilmore, G.; Alfaro, E. J.; Bensby, T.; Flaccomio, E.; Koposov, S. E.; Korn, A. J.; Pancino, E.; Recio-Blanco, A.; Casey, A. R.; Costado, M. T.; Franciosini, E.; Heiter, U.; Hill, V.; Hourihane, A.; Lardo, C.; de Laverny, P.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2016-06-01

Context. The nature of the metallicity gradient inside the solar circle (RGC < 8 kpc) is poorly understood, but studies of Cepheids and a small sample of open clusters suggest that it steepens in the inner disk. Aims: We investigate the metallicity gradient of the inner disk using a sample of inner disk open clusters that is three times larger than has previously been studied in the literature to better characterize the gradient in this part of the disk. Methods: We used the Gaia-ESO Survey (GES) [Fe/H] values and stellar parameters for stars in 12 open clusters in the inner disk from GES-UVES data. Cluster mean [Fe/H] values were determined based on a membership analysis for each cluster. Where necessary, distances and ages to clusters were determined via comparison to theoretical isochrones. Results: The GES open clusters exhibit a radial metallicity gradient of -0.10 ± 0.02 dex kpc-1, consistent with the gradient measured by other literature studies of field red giant stars and open clusters in the range RGC ~ 6-12 kpc. We also measure a trend of increasing [Fe/H] with increasing cluster age, as has also been found in the literature. Conclusions: We find no evidence for a steepening of the inner disk metallicity gradient inside the solar circle as earlier studies indicated. The age-metallicity relation shown by the clusters is consistent with that predicted by chemical evolution models that include the effects of radial migration, but a more detailed comparison between cluster observations and models would be premature. Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under programme ID 188.B-3002 and 193.B-0936. These data products have been processed by the Cambridge Astronomy Survey Unit (CASU) at the Institute of Astronomy, University of Cambridge, and by the FLAMES/UVES reduction team at INAF/Osservatorio Astrofisico di Arcetri. These data have been obtained from the Gaia-ESO Survey Data Archive

Positions of Asteroids Obtained with the GPO Telescope at ESO, Chile and with the Kvistaberg Schmidt Telescope

NASA Astrophysics Data System (ADS)

Lagerkvist, C.-I.; Olofsson, K.; From, A.; Hammarback, G.; Magnusson, P.; Morell, O.

1985-01-01

In this paper we present 101 positions of asteroids obtained during Augnst 1982 with the GPO astrograph at ESO, Chile and with the Kvistaberg Schmidt telescope during September 1979 and February 1981.

Photometric calibration of NGS/POSS and ESO/SRC plates using the NOAO PDS measuring engine. I - Stellar photometry

NASA Technical Reports Server (NTRS)

Cutri, Roc M.; Low, Frank J.; Marvel, Kevin B.

1992-01-01

The PDS/Monet measuring engine at the National Optical Astronomy Observatory was used to obtain photometry of nearly 10,000 stars on the NGS/POSS and 2000 stars on the ESO/SRC Survey glass plates. These measurements have been used to show that global transformation functions exist that allow calibration of stellar photometry from any blue or red plate to equivalent Johnson B and Cousins R photoelectric magnitudes. The four transformation functions appropriate for the POSS O and E and ESO/SRC J and R plates were characterized, and it was found that, within the measurement uncertainties, they vary from plate to plate only by photometric zero-point offsets. A method is described to correct for the zero-point shifts and to obtain calibrated B and R photometry of stellar sources to an average accuracy of 0.3-0.4 mag within the range R between values of 8 and 19.5 for red plates in both surveys, B between values of 9 and 20.5 on POSS blue plates, and B between values of 10 and 20.5 on ESO/SRC blue plates. This calibration procedure makes it possible to obtain rapid photometry of very large numbers of stellar sources.

Effect of Pr Valence State on Interfacial Structure and Electrical Properties of Pr Oxide/PrON/Ge Gate Stack Structure

NASA Astrophysics Data System (ADS)

Kato, Kimihiko; Sakashita, Mitsuo; Takeuchi, Wakana; Kondo, Hiroki; Nakatsuka, Osamu; Zaima, Shigeaki

2011-04-01

In this study, we investigated the valence state and chemical bonding state of Pr in a Pr oxide/PrON/Ge structure. We clarified the relationship between the valence state of Pr and the Pr oxide/Ge interfacial reaction using Pr oxide/Ge and Pr oxide/PrON/Ge samples. We found the formation of three Pr oxide phases in Pr oxide films; hexagonal Pr2O3 (h-Pr2O3) (Pr3+), cubic Pr2O3 (c-Pr2O3) (Pr3+), and c-PrO2 (Pr4+). We also investigated the effect of a nitride interlayer on the interfacial reaction in Pr oxide/Ge gate stacks. In a sample with a nitride interlayer (Pr oxide/PrON/Ge), metallic Pr-Pr bonds are also formed in the c-Pr2O3 film. After annealing in H2 ambient, the diffusion of Ge into Pr oxide is not observed in this sample. Pr-Pr bonds probably prevent the interfacial reaction and Ge oxide formation, considering that the oxygen chemical potential of this film is lower than that of a GeO2/Ge system. On the other hand, the rapid thermal oxidation (RTO) treatment terminates the O vacancies and defects in c-Pr2O3. As a result, c-PrO2 with tetravalent Pr is formed in the Pr oxide/PrON/Ge sample with RTO. In this sample, the leakage current density is effectively decreased in comparison with the sample without RTO. Hydrogen termination works effectively in Pr oxide/PrON/Ge samples with and without RTO, and we can achieve an interface state density of as low as 4 ×1011 eV-1·cm-2.

New Inspiring Planetarium Show Introduces ALMA to the Public

NASA Astrophysics Data System (ADS)

2009-03-01

As part of a wide range of education and public outreach activities for the International Year of Astronomy 2009 (IYA2009), ESO, together with the Association of French Language Planetariums (APLF), has produced a 30-minute planetarium show, In Search of our Cosmic Origins. It is centred on the global ground-based astronomical Atacama Large Millimeter/submillimeter Array (ALMA) project and represents a unique chance for planetariums to be associated with the IYA2009. ESO PR Photo 09a/09 Logo of the ALMA Planetarium Show ESO PR Photo 09b/09 Galileo's first observations with a telescope ESO PR Photo 09c/09 The ALMA Observatory ESO PR Photo 09d/09 The Milky Way band ESO PR Video 09a/09 Trailer in English ALMA is the leading telescope for observing the cool Universe -- the relic radiation of the Big Bang, and the molecular gas and dust that constitute the building blocks of stars, planetary systems, galaxies and life itself. It is currently being built in the extremely arid environment of the Chajnantor plateau, at 5000 metres altitude in the Chilean Andes, and will start scientific observations around 2011. ALMA, the largest current astronomical project, is a revolutionary telescope, comprising a state-of-the-art array of 66 giant 12-metre and 7-metre diameter antennas observing at millimetre and submillimetre wavelengths. In Search of our Cosmic Origins highlights the unprecedented window on the Universe that this facility will open for astronomers. "The show gives viewers a fascinating tour of the highest observatory on Earth, and takes them from there out into our Milky Way, and beyond," says Douglas Pierce-Price, the ALMA Public Information Officer at ESO. Edited by world fulldome experts Mirage3D, the emphasis of the new planetarium show is on the incomparable scientific adventure of the ALMA project. A young female astronomer guides the audience through a story that includes unique animations and footage, leading the viewer from the first observations by Galileo

Expression of cancer/testis antigens in salivary gland carcinomas with reference to MAGE-A and NY-ESO-1 expression in adenoid cystic carcinoma.

PubMed

Beppu, Shintaro; Ito, Yohei; Fujii, Kana; Saida, Kosuke; Takino, Hisashi; Masaki, Ayako; Murase, Takayuki; Kusafuka, Kimihide; Iida, Yoshiyuki; Onitsuka, Tetsuro; Yatabe, Yasushi; Hanai, Nobuhiro; Hasegawa, Yasuhisa; Ijichi, Kei; Murakami, Shingo; Inagaki, Hiroshi

2017-08-01

Cancer/testis antigens (CTAs) are detected in cancer cells but not in healthy normal tissues, with the exception of gametogenic tissues. CTAs are highly immunogenic proteins, and thus represent ideal targets for cytotoxic T-lymphocyte-mediated specific immune therapy. The aim of this study was to screen CTA expression in various types of salivary gland carcinoma and to clarify clinicopathological significance of MAGE-A and NY-ESO-1 expression in adenoid cystic carcinomas (AdCCs) of the salivary gland, which is one of the most common salivary gland carcinomas, and usually has a fatal outcome. We used immunohistochemistry to examine the expression of four CTAs (MAGE-A, NY-ESO-1, CT7, and GAGE7) in various types of salivary gland carcinoma (n = 95). When carcinoma cases were divided into low-grade and intermediate/high-grade types, NY-ESO-1 and CT7 were expressed more frequently in intermediate/high-grade carcinomas. We then focused on MAGE-A and NY-ESO-1 expression in a large cohort of adenoid cystic carcinomas (AdCCs) (n = 46). MAGE-A and NY-ESO-1 were frequently expressed in AdCC; specifically, MAGE-A was expressed in >60% of the AdCC cases. MAGE-A expression and tumour site (minor salivary gland) were identified as independent risk factors for locoregional tumour recurrence. These findings suggest that CTAs may be expressed in a variety of salivary gland carcinomas, especially in those with higher histological grades. In addition, MAGE-A, which is frequently expressed in AdCC cases, may be a useful prognostic factor for poorer locoregional recurrence-free survival. © 2017 John Wiley & Sons Ltd.

"First Light" for HARPS at La Silla

NASA Astrophysics Data System (ADS)

2003-03-01

. PR Photo 08b/03 : The HARPS spectrograph . PR Photo 08c/03 : HARPS spectrum of the star HD100623 ("raw"). PR Photo 08d/03 : Extracted spectral tracing of the star HD100623 . PR Photo 08e/03 : Measured stability of HARPS. The HARPS Spectrograph ESO PR Photo 08a/03 ESO PR Photo 08a/03 [Preview - JPEG: 449 x 400 pix - 58k [Normal - JPEG: 897 x 800 pix - 616k] [Full-Res - JPEG: 1374 x 1226 pix - 1.3M] ESO PR Photo 08b/03 ESO PR Photo 08b/03 [Preview - JPEG: 500 x 400 pix - 83k [Normal - JPEG: 999 x 800 pix - 727k] [Full-Res - JPEG: 1600 x 1281 pix - 1.3M] Captions : PR Photo 08a/03 and PR Photo 08b/03 show the HARPS spectrograph during laboratory tests. The vacuum tank is open so that some of the high-precision components inside can be seen. On PR Photo 08a/03 , the large optical grating by which the incoming stellar light is dispersed is visible on the top of the bench; it measures 200 x 800 mm. HARPS is a unique fiber-fed "echelle" spectrograph able to record at once the visible range of a stellar spectrum (wavelengths from 380 - 690 nm) with very high spectral resolving power (better than R = 100,000 ). Any light losses inside the instrument caused by reflections of the starlight in the various optical components (mirrors and gratings), have been minimised and HARPS therefore works very efficiently . First observations ESO PR Photo 08c/03 ESO PR Photo 08c/03 [Preview - JPEG: 400 x 490 pix - 52k [Normal - JPEG: 800 x 980 pix - 362k] [Full-Res - JPEG: 1976 x 1195 pix - 354k] ESO PR Photo 08d/03 ESO PR Photo 08d/03 [Preview - JPEG: 485 x 400 pix - 53k [Normal - JPEG: 969X x 800 pix - 160k] Captions : PR Photo 08c/03 displays a HARPS untreated ("raw") exposure of the star HD100623 , of the comparatively cool stellar spectral type K0V. The frame shows the complete image as recorded with the 4000 x 4000 pixel CCD detector in the focal plane of the spectrograph. The horizontal white lines correspond to the stellar spectrum, divided into 70 adjacent spectral bands which

Live imaging of prions reveals nascent PrPSc in cell-surface, raft-associated amyloid strings and webs

PubMed Central

Rouvinski, Alexander; Karniely, Sharon; Kounin, Maria; Moussa, Sanaa; Goldberg, Miri D.; Warburg, Gabriela; Lyakhovetsky, Roman; Papy-Garcia, Dulce; Kutzsche, Janine; Korth, Carsten; Carlson, George A.; Godsave, Susan F.; Peters, Peter J.; Luhr, Katarina; Kristensson, Krister

2014-01-01

Mammalian prions refold host glycosylphosphatidylinositol-anchored PrPC into β-sheet–rich PrPSc. PrPSc is rapidly truncated into a C-terminal PrP27-30 core that is stable for days in endolysosomes. The nature of cell-associated prions, their attachment to membranes and rafts, and their subcellular locations are poorly understood; live prion visualization has not previously been achieved. A key obstacle has been the inaccessibility of PrP27-30 epitopes. We overcame this hurdle by focusing on nascent full-length PrPSc rather than on its truncated PrP27-30 product. We show that N-terminal PrPSc epitopes are exposed in their physiological context and visualize, for the first time, PrPSc in living cells. PrPSc resides for hours in unexpected cell-surface, slow moving strings and webs, sheltered from endocytosis. Prion strings observed by light and scanning electron microscopy were thin, micrometer-long structures. They were firmly cell associated, resisted phosphatidylinositol-specific phospholipase C, aligned with raft markers, fluoresced with thioflavin, and were rapidly abolished by anti-prion glycans. Prion strings and webs are the first demonstration of membrane-anchored PrPSc amyloids. PMID:24493590

Detection of magnetic field in the B2 star ρ Ophiuchi A with ESO FORS2

NASA Astrophysics Data System (ADS)

Pillitteri, I.; Fossati, L.; Castro Rodriguez, N.; Oskinova, L.; Wolk, S. J.

2018-02-01

Circumstantial evidence suggests that magnetism and enhanced X-ray emission are likely correlated in early B-type stars: similar fractions of them ( 10%) are strong and hard X-ray sources and possess strong magnetic fields. It is also known that some B-type stars have spots on their surface. Yet up to now no X-ray activity associated with spots on early-type stars was detected. In this Letter we report the detection of a magnetic field on the B2V star ρ Oph A. Previously, we assessed that the X-ray activity of this star is associated with a surface spot, herewith we establish its magnetic origin. We analyze spectra of ρ Oph A obtained with the FORS2 spectrograph at ESO Very Large Telescope (VLT) at two epochs, and detect a longitudinal component of the magnetic field of the order of 500 G in one of the datasets. The detection of the magnetic field only at one epoch can be explained by stellar rotation which is also invoked to explain observed periodic X-ray activity. From archival HARPS ESO VLT high resolution spectra we derived the fundamental stellar parameters of ρ Oph A and further constrained its age. We conclude that ρ Oph A provides strong evidence for the presence of active X-ray emitting regions on young magnetized early type stars. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 099.D-0067(A) and 078.C-0403(A).

The Eagle's EGGs

NASA Astrophysics Data System (ADS)

2001-12-01

VLT ISAAC Looks for Young Stars in the Famous "Pillars of Creation" Summary Through imaging at infrared wavelengths, evidence has been found for recent star formation in the so-called "Pillars of Creation" in the Eagle Nebula (also known as Messier 16 ), made famous when the NASA/ESA Hubble Space Telescope (HST) obtained spectacular visible-wavelength images of this object in 1995. Those huge pillars of gas and dust are being sculpted and illuminated by bright and powerful high-mass stars in the nearby NGC 6611 young stellar cluster . The Hubble astronomers suggested that perhaps even younger stars were forming inside. Using the ISAAC instrument on the VLT 8.2-m ANTU telescope at the ESO Paranal Observatory , European astronomers have now made a wide-field infrared image of the Messier 16 region with excellent spatial resolution, enabling them to penetrate the obscuring dust and search for light from newly born stars . Two of the three pillars are seen to have very young, relatively massive stars in their tips. Another dozen or so lower-mass stars seem to be associated with the small "evaporating gaseous globules (EGGs)" that the Hubble astronomers had discovered scattered over the surface of the pillars. These findings bring new evidence to several key questions about how stars are born . Was the formation of these new stars triggered as the intense ultraviolet radiation from the NGC 6611 stars swept over the pillars, or were they already there? Will the new stars be prematurely cut off from surrounding gas cloud, thus stunting their growth? If the new stars have disks of gas and dust around them, will they be destroyed before they have time to form planetary systems? PR Photo 37a/01 : Full wide-field ISAAC image of the Eagle Nebula. PR Photo 37b/01 : Close-up view of the ISAAC image , showing the famous "Pillars of Creation". PR Photo 37c/01 : Enlargement of the head of Column 1 . PR Photo 37d/01 : Enlargement of the head of Column 2 . PR Photo 37e/01

Extending ORAC-DR for Offline Processing of ESO, INGRID, and Classic Cam data

NASA Astrophysics Data System (ADS)

Currie, M. J.

2004-07-01

ORAC-DR--a flexible reduction pipeline---was originally developed by the Joint Astronomy Centre for real-time inspection of reduced data at its telescopes. Starlink is extending ORAC-DR to process at home institutions data from other observatories, notably ESO, whose instruments make no provision for ORAC-DR. I outline the problems encountered and solutions implemented or proposed to apply ORAC-DR to the infra-red instruments ISAAC, NACO, INGRID, and Classic~Cam.

Desert Pathfinder at Work

NASA Astrophysics Data System (ADS)

2005-09-01

The Atacama Pathfinder Experiment (APEX) project celebrates the inauguration of its outstanding 12-m telescope, located on the 5100m high Chajnantor plateau in the Atacama Desert (Chile). The APEX telescope, designed to work at sub-millimetre wavelengths, in the 0.2 to 1.5 mm range, passed successfully its Science Verification phase in July, and since then is performing regular science observations. This new front-line facility provides access to the "Cold Universe" with unprecedented sensitivity and image quality. After months of careful efforts to set up the telescope to work at the best possible technical level, those involved in the project are looking with satisfaction at the fruit of their labour: APEX is not only fully operational, it has already provided important scientific results. "The superb sensitivity of our detectors together with the excellence of the site allow fantastic observations that would not be possible with any other telescope in the world," said Karl Menten, Director of the group for Millimeter and Sub-Millimeter Astronomy at the Max-Planck-Institute for Radio Astronomy (MPIfR) and Principal Investigator of the APEX project. ESO PR Photo 30/05 ESO PR Photo 30/05 Sub-Millimetre Image of a Stellar Cradle [Preview - JPEG: 400 x 627 pix - 200k] [Normal - JPEG: 800 x 1254 pix - 503k] [Full Res - JPEG: 1539 x 2413 pix - 1.3M] Caption: ESO PR Photo 30/05 is an image of the giant molecular cloud G327 taken with APEX. More than 5000 spectra were taken in the J=3-2 line of the carbon monoxide molecule (CO), one of the best tracers of molecular clouds, in which star formation takes place. The bright peak in the north of the cloud is an evolved star forming region, where the gas is heated by a cluster of new stars. The most interesting region in the image is totally inconspicuous in CO: the G327 hot core, as seen in methanol contours. It is a truly exceptional source, and is one of the richest sources of emission from complex organic molecules in the

Multiple Eyes for the VLT

NASA Astrophysics Data System (ADS)

2002-01-01

First System of Deployable Multi-Integral Field Units Ready Summary The ESO Very Large Telescope (VLT) at the Paranal Observatory is being equipped with many state-of-the-art astronomical instruments that will allow observations in a large number of different modes and wavebands. Soon to come is the Fibre Large Array Multi-Element Spectrograph (FLAMES) , a project co-ordinated by ESO. It incorporates several complex components, now being constructed at various research institutions in Europe and Australia. One of these, a true technological feat, is a unique system of 15 deployable fibre bundles, the so-called Integral Field Units (IFUs) . They can be accurately positioned within a sky field-of-view measuring no less that 25 arcmin in diameter, i.e., almost as large as the full Moon . Each of the IFUs looks like an insect's eye and images a small sky area (3 x 2 arcsec 2 ) with a multiple microlens. From each IFU, 20 narrow light beams are sent via optical fibres to an advanced spectrograph. All 300 spectra are recorded simultaneously by a sensitive digital camera. A major advantage of this technique is that, contrary usual spectroscopic observations in which spectral information is obtained along a (one-dimensional) line on the sky, it now allows (two-dimensional) area spectroscopy . This will permit extremely efficient spectral observations of many celestial objects, including faint galaxies, providing detailed information about their internal structure and motions. Such studies will have an important impact on our understanding, e.g., of the early evolution of galaxies , the main building blocks in the Universe. The IFUs have been developed by a team of astronomers and engineers [2] at the Observatoire de Paris-Meudon. All IFU components are now at the ESO Headquarters in Garching (Germany) where they are being checked and integrated into the instrument [3]. PR Photo 03a/02 : The GIRAFFE spectrograph in the ESO Assembly Hall (Garching, Germany) . PR Photo 03b/02

Is This Speck of Light an Exoplanet?

NASA Astrophysics Data System (ADS)

2004-09-01

nature of this intriguing object. Thus, the astronomers refer to it as a "Giant Planet Candidate Companion (GPCC)" [4]. Observations will now be made to ascertain whether the motion in the sky of GPCC is compatible with that of a planet orbiting 2M1207. This should become evident within 1-2 years at the most. PR Photo 26a/04: NACO image of the brown dwarf object 2M1207 and GPCC PR Photo 26b/04: Near-infrared spectrum of the brown dwarf object 2M1207 and GPCC PR Photo 26c/04: Comparison between the possible 2M1207 system and the solar system Just a speck of light ESO PR Photo 26a/04 ESO PR Photo 26a/04 The Brown Dwarf Object 2M1207 and GPCC [Preview - JPEG: 400 x 471 pix - 65k] [Normal - JPEG: 800 x 942 pix - 158k] Caption: ESO PR Photo 26a/04 is a composite image of the brown dwarf object 2M1207 (centre) and the fainter object seen near it, at an angular distance of 778 milliarcsec. Designated "Giant Planet Candidate Companion" by the discoverers, it may represent the first image of an exoplanet. Further observations, in particular of its motion in the sky relative to 2M1207 are needed to ascertain its true nature. The photo is based on three near-infrared exposures (in the H, K and L' wavebands) with the NACO adaptive-optics facility at the 8.2-m VLT Yepun telescope at the ESO Paranal Observatory. Since 1998, a team of European and American astronomers [2] is studying the environment of young, nearby "stellar associations", i.e., large conglomerates of mostly young stars and the dust and gas clouds from which they were recently formed. The stars in these associations are ideal targets for the direct imaging of sub-stellar companions (planets or brown dwarf objects). The leader of the team, ESO astronomer Gael Chauvin notes that "whatever their nature, sub-stellar objects are much hotter and brighter when young - tens of millions of years - and therefore can be more easily detected than older objects of similar mass". The team especially focused on the study of the TW

DEEP U BAND AND R IMAGING OF GOODS-SOUTH: OBSERVATIONS, DATA REDUCTION AND FIRST RESULTS ,

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nonino, M.; Cristiani, S.; Vanzella, E.

2009-08-01

We present deep imaging in the U band covering an area of 630 arcmin{sup 2} centered on the southern field of the Great Observatories Origins Deep Survey (GOODS). The data were obtained with the VIMOS instrument at the European Southern Observatory (ESO) Very Large Telescope. The final images reach a magnitude limit U {sub lim} {approx} 29.8 (AB, 1{sigma}, in a 1'' radius aperture), and have good image quality, with full width at half-maximum {approx}0.''8. They are significantly deeper than previous U-band images available for the GOODS fields, and better match the sensitivity of other multiwavelength GOODS photometry. The deepermore » U-band data yield significantly improved photometric redshifts, especially in key redshift ranges such as 2 < z < 4, and deeper color-selected galaxy samples, e.g., Lyman break galaxies at z {approx} 3. We also present the co-addition of archival ESO VIMOS R-band data, with R {sub lim} {approx} 29 (AB, 1{sigma}, 1'' radius aperture), and image quality {approx}0.''75. We discuss the strategies for the observations and data reduction, and present the first results from the analysis of the co-added images.« less

Synthesis and characterization of physical properties of Gd2O2S:Pr3+ semi-nanoflower phosphor

NASA Astrophysics Data System (ADS)

Bagheri, A.; Rezaee Ebrahim Saraee, Kh.; Shakur, H. R.; Zamani Zeinali, H.

2016-05-01

Pure gadolinium oxysulfide phosphor (Gd2O2S) and trivalent praseodymium-doped gadolinium oxysulfide phosphor (Gd2O2S:Pr3+) scintillators with semi-nanoflower crystalline structures were successfully synthesized through a precipitation method and subsequent calcination treatment as a converter for X-ray imaging detectors. The characterization such as the crystal structures and nanostructure of Gd2O2S:Pr3+ scintillator measured by XRD and FeE-SEM experiment. The optical properties of Gd2O2S:Pr3+ scintillator were studied. Luminescence spectra of Gd2O2S:Pr3+ under 320 nm UV excitation show a green emission at near 511 nm corresponding to the 3P0-3H4 of Pr ions. After scintillation properties of synthesized Gd2O2S:Pr3+ scintillator investigated, Gd2O2S:Pr3+ scintillating film fabricated on a glass substrate by a sedimentation method. X-ray imaging of the fabricated scintillators confirmed that the Gd2O2S:Pr3+ scintillator could be used for radiography applications in which good spatial resolution is needed.

Young Stars in Old Galaxies - a Cosmic Hide and Seek Game

NASA Astrophysics Data System (ADS)

2002-05-01

Surprise Discovery with World's Leading Telescopes [1] Summary Combining data from the NASA/ESA Hubble Space Telescope (HST) and the ESO Very Large Telescope (VLT) , a group of European and American astronomers [2] have made an unexpected, major discovery. They have identified a huge number of "young" stellar clusters , only a few billion years old [3], inside an "old" elliptical galaxy (NGC 4365), probably aged some 12 billion years. For the first time, it has been possible to identify several distinct periods of star-formation in a galaxy as old as this one . Elliptical galaxies like NGC 4365 have until now been considered to have undergone one early star-forming period and thereafter to be devoid of any star formation. However, the combination of the best and largest telescopes in space and on the ground has now clearly shown that there is more than meets the eye. This important new information will help to understand the early history of galaxies and the general theory of star formation in the Universe . PR Photo 15a/02 : Combined HST+VLT image of elliptical galaxy NGC 4365 PR Photo 15b/02 : Same image, with "old" and "young" stellar clusters indicated PR Photo 15c/02 : Animated GIF image, showing the three cluster populations observed in NGC 4365 Do elliptical galaxies only contain old stars? One of the challenges of modern astronomy is to understand how galaxies, those large systems of stars, gas and dust, form and evolve. In this connection, a central question has always been to learn when most of the stars in the Universe formed. Did this happen at a very early stage, within a few billion years after the Big Bang? Or were a significant number of the stars we now observe formed much more recently? Spectacular collisions between galaxies take place all the time, triggering the formation of thousands or even millions of stars, cf. ESO PR Photo 29b/99 of the dramatic encounter between NGC 6872 and IC 4970. However, when looking at the Universe as a whole, most

Highlights from the CERN/ESO/NordForsk ''Gender in Physics Day''

NASA Astrophysics Data System (ADS)

Primas, F.; Guinot, G.; Strandberg, L.

2017-03-01

In their role as observers on the EU Gender Equality Network in the European Research Area (GENERA) project, funded under the Horizon 2020 framework, CERN, ESO and NordForsk joined forces and organised a Gender in Physics Day at the CERN Globe of Science and Innovation. The one-day conference aimed to examine innovative activities promoting gender equality, and to discuss gender-oriented policies and best practice in the European Research Area (with special emphasis on intergovernmental organisations), as well as the importance of building solid networks. The event was very well attended and was declared a success. The main highlights of the meeting are reported.

STRESS a SN survey at ESO

NASA Astrophysics Data System (ADS)

Botticella, M. T.

We performed the Southern inTermediate Redshift ESO Supernova Search (STRESS), a survey specifically designed to measure the rate of both SNe Ia and CC SNe, in order to obtain a direct comparison of the high redshift and local rates and to investigate the dependence of the rates on specific galaxy properties, most notably their colour. We found that the type Ia SN rate, at mean redshift z = 0.3, is 0.22+0.10+0.16-0.08-0.14 h270 SNu, while the CC SN rate, at z = 0.21, is 0.82+0.31+0.300.24-0.26 h270 SNu. The quoted errors are the statistical and systematic uncertainties. With respect to the local value, the CC SN rate at z = 0.2 is higher by a factor of ˜ 2, whereas the type Ia SN rate remains almost constant. We also measured the SN rates in the red and blue galaxies and found that the SN Ia rate seems to be constant in galaxies of different colour, whereas the CC SN rate seems to peak in blue galaxies, as in the local Universe. Finally we exploited the link between SFH and SN rates to predict the evolutionary behaviour of the SN rates and compare it with the path indicated by observations.

Intelligent ePR system for evidence-based research in radiotherapy: proton therapy for prostate cancer.

PubMed

Le, Anh H; Liu, Brent; Schulte, Reinhard; Huang, H K

2011-11-01

Proton therapy (PT) utilizes high energy particle proton beam to kill cancer cells at the target region for target cancer therapy. Due to the physical properties of the proton beam, PT delivers dose with higher precision and no exit dose compared to conventional radiotherapy. In PT, patient data are distributed among multiple systems, a hindrance to research on efficacy and effectiveness. A data mining method and a treatment plan navigator utilizing the infrastructure and data repository of a PT electronic patient record (ePR) was developed to minimize radiation toxicity and improve outcomes in prostate cancer treatment. MATERIALS/METHOD(S): The workflow of a proton therapy treatment in a radiation oncology department was reviewed, and a clinical data model and data flow were designed. A prototype PT ePR system with DICOM compliance was developed to manage prostate cancer patient images, treatment plans, and related clinical data. The ePR system consists of four main components: (1) Data Gateway; (2) ePR Server; (3) Decision Support Tools; and (4) Visualization and Display Tools. Decision support and visualization tools are currently developed based on DICOM images, DICOM-RT and DICOM-RT-ION objects data from prostate cancer patients treated with hypofractionation protocol proton therapy were used for evaluating ePR system effectiveness. Each patient data set includes a set of computed tomography (CT) DICOM images and four DICOM-RT and RT-ION objects. In addition, clinical outcomes data collected from PT cases were included to establish a knowledge base for outcomes analysis. A data mining search engine and an intelligent treatment plan navigator (ITPN) were developed and integrated with the ePR system. Evaluation was based on a data set of 39 PT patients and a hypothetical patient. The ePR system was able to facilitate the proton therapy workflow. The PT ePR system was feasible for prostate cancer patient treated with hypofractionation protocol in proton therapy

NTT Observations Indicate that Brown Dwarfs Form Like Stars

NASA Astrophysics Data System (ADS)

2001-06-01

-floating Brown Dwarfs in the Milky Way galaxy. Both facts would appear to imply a stellar, rather than a planet-like origin for these objects. However, one might also explain these observations if most Brown Dwarfs initially formed as companions to stars (within circumstellar disks), but were later ejected from the systems, e.g., because of gravitational effects during encounters with other stars. So the issue of Brown Dwarf origin is still unsettled. NTT observations of substellar objects in the Orion Nebula ESO PR Photo 22a/01 ESO PR Photo 22a/01 [Preview - JPEG: 400 x 434 pix - 192k] [Normal - JPEG: 800 x 877 pix - 496k] [Full Resolution - JPEG: 1772 x 1943 pix - 1.2Mb Caption : PR Photo 22a/01 shows a colour composite of near-infrared images of the central regions of the Orion Nebula, obtained on March 14, 2000, with the SOFI instrument at the ESO 3.5-m New Technology Telescope (NTT) at La Silla. Three exposures were made through J- (wavelength 1.25 µm here colour-coded as "blue"), H- (1.65 µm; "green") and Ks-filters (2.16 µm; "red"), respectively. The central group of bright stars is the famous "Trapezium" . The total effective exposure time was 86.4 seconds per band. The sky field measures about 4.9 x 4.9 arcmin 2 (1024 x 1024 pix 2 ). North is up and East is left. ESO PR Photo 22b/01 ESO PR Photo 22b/01 [Preview - JPEG: 400 x 439 pix - 35k] [Normal - JPEG: 800 x 877 pix - 90k] Caption : PR Photo 22b/01 contains the corresponding "finding chart" with the positions of the very young Brown Dwarfs in the Orion Nebula that were studied during the present investigation. The starlike symbols represent the brightest stars in PR Photo 22a/01 and are plotted for reference. In this chart, very young Brown Dwarfs are represented by a double open circle (if a dusty disk was detected) or with a single open circle (if no dusty disk was detected). The scale is exactly as in PR Photo 22a/01 . ESO PR Photo 22c/01 ESO PR Photo 22c/01 [Animated GIF: 482 x 465 pix - 248k] Caption : PR

Live Webcasts from CERN and ESO for European Science and Technology Week

NASA Astrophysics Data System (ADS)

2002-10-01

Visit http://www.cern.ch/sci-tech on 7 - 8 November to find out what modern Europeans can't live without. Seven of Europe's leading Research Organizations [1] are presenting three live Webcasts from CERN in a joint outreach programme for the European Science and Technology Week . The aim of Sci-Tech... couldn't be without it! is to show how today's society couldn't be without cutting-edge scientific research. See also ESO Press Release 05/02. Northern Europeans can't imagine their households without ovens, whereas Southern Europeans identify the refrigerator as the most essential household appliance. In the area of communications, cars and motorbikes are clearly the technologies of choice in Italy, but are regarded as less important in countries like Norway and Germany. For entertainment, the personal computer is a clear winner as the device is considered most essential by all Europeans, followed by the TV and the Internet. This hit parade of technological marvels is the result of a phone and online survey conducted by the Sci-Tech... couldn't be without it! team for this year's European Science and Technology Week on 4-10 November. The technologies Europeans could not be without, form the starting point of three entertaining and informative Webcast shows in Italian (Thursday 7 November at 10:00 CET), French (Thursday 7 November at 15:00 CET) and English (Friday 8 November at 15:00 CET), broadcast live on the Internet from a studio at CERN. During these Webcasts scientists from the seven research Organizations and their industrial partners Sun Microsystems, Siemens, L'Oreal and Luminex will engage - from the CERN studio or from remote locations through teleconference links - an audience of Internauts all over the world. The public will be taken inside their most popular gadgets to discover the science that made them possible and how vital fundamental research has been in the creation of modern technology. Fundamental science will be brought as close as possible to

VLT Unit Telescopes Named at Paranal Inauguration

NASA Astrophysics Data System (ADS)

1999-03-01

Southern Cross) and YEPUN (UT4; ye-poon ; Sirius), respectively. An audio sequence with these names pronounced by a native speaker is available below: [RealMedia - Audio only - 164k] "First Light" of UT2 Following the installation of the main mirror in its cell and a 20-hour working session to put the complex secondary mirror and its support in place, the UT2, now Kueyen , achieved (technical) first light in the morning of March 1, 1999, when an image was obtained of a bright star. It showed this telescope to be in good optical shape and further adjustments of the optical and mechanical systems are expected soon to result in some "astronomical" images. The announcement of this important event was made by the ESO Director during the opening session of the VLT Symposium that was held in Antofagasta during March 1-4, 1999. This meeting attracted over 250 scientists from all over world. It provided a most useful opportunity to discuss future scientific programmes with the VLT and other large telescopes. The participants were left with the impression of mounting expectations, just four weeks before the first VLT Unit Telescope, Antu (UT1), will receive the first visiting astronomers. More images from UT1 ESO PR Photo 17c/99 ESO PR Photo 17c/99 [Preview - JPEG: 400 x 667 pix - 332k] [Normal - JPEG: 800 x 1334 pix - 1.3M] [High-Res - JPEG: 2108 x 3450 pix - 2.8M] Caption to PR Photo 17c/99 : This colour composite photo of the Chamaeleon I area is based on six 1-min exposures obtained with VLT UT1 + FORS1 in the V, R and I bands. The sky field measures 6.8 x 11.2 arcmin 2 ; North is up and East is left [1]. Despite the extensive preparations for the Paranal Inguration and the VLT Symposium, excellent progress is being made during the final tuning of Antu (UT1) and its instruments for the "hand-over" to the astronomers on April 1, 1999. This involves exposures in many different modes and of different sky regions. Another impressive photo is shown here that was obtained some nights

AirMSPI Level 1B2 V006 New Data for the SPEX-PR Campaign

Atmospheric Science Data Center

2018-05-08

... Imager (AirMSPI) Level 1B2 data products for the SPEX engineering flights + Porter Ranch gas leak overflights (SPEX-PR) flight ... AirMSPI data contains all targets acquired during the SPEX engineering flights + Porter Ranch gas leak overflights (SPEX-PR) flight ...

Domain structures and Prco antisite point defects in double-perovskite PrBaCo2O5+δ and PrBa0.8Ca0.2Co2O5+δ.

PubMed

Ding, Yong; Chen, Yu; Pradel, Ken C; Zhang, Weilin; Liu, Meilin; Wang, Zhong Lin

2018-06-15

Owing to the excellent mixed-ionic and electronic conductivity and fast oxygen kinetics at reduced temperature (<800 °C), double-perovskite oxides such as PrBaCo 2 O 5+δ exhibit excellent properties as an oxygen electrode for solid oxide fuel cells (SOFCs). Using transmission electron microscopy (TEM), we revealed high-density antiphase domain boundaries (APBs) and 90° domain walls in PrBaCo 2 O 5+δ grains. Besides the regular lamellar 90° domain walls in {021} planes, irregular fine 90° domains are attached to the curved APBs. Electron energy-loss spectroscopy (EELS) reveals the composition variation across some of the 90° domain walls. There are fewer Co and more Ba ions approaching the 90° domain walls, while the changes in Pr and O ions are not detectable. We assume that the extra Ba 2+ cations replace the Pr 3+ cations, while the Pr 3+ cations go to the Co site to form Pr Co antisite point defects and become Pr 4+ . In this case, the Pr 4+ cations will help to balance the local charges and have compatible ionic radius with that of Co 3+ . The local strain field around the 90° domain walls play a crucial role in the stabilization of such Pr Co antisite point defects. The antisite point defects have been observed in our high-resolution TEM images and aberration-corrected high-angle annular dark-field (HAADF) scanning TEM images. After Ca 2+ doped into PrBaCo 2 O 5+δ to improve the structure stability, we observed tweed structures in the PrBa 0.8 Ca 0.2 Co 2 O 5+δ grain. The tweed structure is composed of high-density intersected needle-shaped 90° domain walls, which is linked to a strong local strain field and composition variation. Even when the temperature is increased to 750 °C, the domain structures are still stable as revealed by our in situ TEM investigation. Therefore, the influence of the domain structures and the Pr Co antisite defects on the ionic and electric conductivities must be considered. Copyright © 2018. Published by Elsevier

The Gaia-ESO Survey: Churning through the Milky Way

NASA Astrophysics Data System (ADS)

Hayden, M. R.; Recio-Blanco, A.; de Laverny, P.; Mikolaitis, S.; Guiglion, G.; Hill, V.; Gilmore, G.; Randich, S.; Bayo, A.; Bensby, T.; Bergemann, M.; Bragaglia, A.; Casey, A.; Costado, M.; Feltzing, S.; Franciosini, E.; Hourihane, A.; Jofre, P.; Koposov, S.; Kordopatis, G.; Lanzafame, A.; Lardo, C.; Lewis, J.; Lind, K.; Magrini, L.; Monaco, L.; Morbidelli, L.; Pancino, E.; Sacco, G.; Stonkute, E.; Worley, C. C.; Zwitter, T.

2018-01-01

Context. There have been conflicting results with respect to the extent that radial migration has played in the evolution of the Galaxy. Additionally, observations of the solar neighborhood have shown evidence of a merger in the past history of the Milky Way that drives enhanced radial migration. Aims: We attempt to determine the relative fraction of stars that have undergone significant radial migration by studying the orbital properties of metal-rich ([Fe/H] > 0.1) stars within 2 kpc of the Sun. We also aim to investigate the kinematic properties, such as velocity dispersion and orbital parameters, of stellar populations near the Sun as a function of [Mg/Fe] and [Fe/H], which could show evidence of a major merger in the past history of the Milky Way. Methods: We used a sample of more than 3000 stars selected from the fourth internal data release of the Gaia-ESO Survey. We used the stellar parameters from the Gaia-ESO Survey along with proper motions from PPMXL to determine distances, kinematics, and orbital properties for these stars to analyze the chemodynamic properties of stellar populations near the Sun. Results: Analyzing the kinematics of the most metal-rich stars ([Fe/H] > 0.1), we find that more than half have small eccentricities (e< 0.2) or are on nearly circular orbits. Slightly more than 20% of the metal-rich stars have perigalacticons Rp> 7 kpc. We find that the highest [Mg/Fe], metal-poor populations have lower vertical and radial velocity dispersions compared to lower [Mg/Fe] populations of similar metallicity by 10 km s-1. The median eccentricity increases linearly with [Mg/Fe] across all metallicities, while the perigalacticon decreases with increasing [Mg/Fe] for all metallicities. Finally, the most [Mg/Fe]-rich stars are found to have significant asymmetric drift and rotate more than 40 km s-1 slower than stars with lower [Mg/Fe] ratios. Conclusions: While our results cannot constrain how far stars have migrated, we propose that migration

The Gaia-ESO Survey: Empirical determination of the precision of stellar radial velocities and projected rotation velocities

NASA Astrophysics Data System (ADS)

Jackson, R. J.; Jeffries, R. D.; Lewis, J.; Koposov, S. E.; Sacco, G. G.; Randich, S.; Gilmore, G.; Asplund, M.; Binney, J.; Bonifacio, P.; Drew, J. E.; Feltzing, S.; Ferguson, A. M. N.; Micela, G.; Neguerela, I.; Prusti, T.; Rix, H.-W.; Vallenari, A.; Alfaro, E. J.; Allende Prieto, C.; Babusiaux, C.; Bensby, T.; Blomme, R.; Bragaglia, A.; Flaccomio, E.; Francois, P.; Hambly, N.; Irwin, M.; Korn, A. J.; Lanzafame, A. C.; Pancino, E.; Recio-Blanco, A.; Smiljanic, R.; Van Eck, S.; Walton, N.; Bayo, A.; Bergemann, M.; Carraro, G.; Costado, M. T.; Damiani, F.; Edvardsson, B.; Franciosini, E.; Frasca, A.; Heiter, U.; Hill, V.; Hourihane, A.; Jofré, P.; Lardo, C.; de Laverny, P.; Lind, K.; Magrini, L.; Marconi, G.; Martayan, C.; Masseron, T.; Monaco, L.; Morbidelli, L.; Prisinzano, L.; Sbordone, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2015-08-01

Context. The Gaia-ESO Survey (GES) is a large public spectroscopic survey at the European Southern Observatory Very Large Telescope. Aims: A key aim is to provide precise radial velocities (RVs) and projected equatorial velocities (vsini) for representative samples of Galactic stars, which will complement information obtained by the Gaia astrometry satellite. Methods: We present an analysis to empirically quantify the size and distribution of uncertainties in RV and vsini using spectra from repeated exposures of the same stars. Results: We show that the uncertainties vary as simple scaling functions of signal-to-noise ratio (S/N) and vsini, that the uncertainties become larger with increasing photospheric temperature, but that the dependence on stellar gravity, metallicity and age is weak. The underlying uncertainty distributions have extended tails that are better represented by Student's t-distributions than by normal distributions. Conclusions: Parametrised results are provided, which enable estimates of the RV precision for almost all GES measurements, and estimates of the vsini precision for stars in young clusters, as a function of S/N, vsini and stellar temperature. The precision of individual high S/N GES RV measurements is 0.22-0.26 km s-1, dependent on instrumental configuration. Based on observations collected with the FLAMES spectrograph at VLT/UT2 telescope (Paranal Observatory, ESO, Chile), for the Gaia- ESO Large Public Survey (188.B-3002).Full Table 2 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/580/A75

Comet or Asteroid?

NASA Astrophysics Data System (ADS)

1997-11-01

. Thus such asteroids are known as the Trojans and the mentioned programme is referred to as the Uppsala-DLR Trojan Survey . In September and October/November 1996, the ESO Schmidt telescope was used to cover about 900 square degrees twice centered on the sky field in the direction of the Jovian L4 point. The observations were made by ESO night-assistants Guido and Oscar Pizarro . By inspection of those from September, Claes-Ingvar Lagerkvist found a total of about 400 Trojan asteroids, most of which were hitherto unknown. Their accurate positions were measured on a two-coordinate measuring machine at the ESO Headquarters in Garching (Germany). During the same period, the 0.6-m Bochum telescope at La Silla was used for additional observations of positions and magnitudes. An asteroid with a tail? ESO Press Photo 31a/97 ESO Press Photo 31a/97 [JPG, 120k] Caption: Discovery image of P/1997 T3 , obtained on October 1, 1997, with the 1-metre ESO Schmidt telescope at the La Silla observatory in the Chilean Atacama desert. The object is seen as a small straight and sharp `asteroidal' trail (in 4 o'clock orientation) on the lower right side of the strong white line in the middle of the field, directly opposite the white dot (these marks were placed in order to mark the position of the new object on the film). A new object was found by Claes-Ingvar Lagerkvist on a film obtained with the ESO 1-metre Schmidt telescope on October 1, 1997. The appearance was that of a point light source, i.e. it was presumably of asteroidal nature , cf. ESO Press Photo 31a/97. ESO Press Photo 31b/97 ESO Press Photo 31b/97 [JPG, 45k] Caption: P/1997 T3 on October 6, 1997 at 05:13:54 UT. This image of the new object (slightly above and to the left of the centre of the field) was obtained with the 0.6-m Bochum telescope at La Silla; the observer was Andreas Nathues . The tail is faintly visible to the lower left of the point-like object (in the 7 o'clock direction). However, when Andreas Nathues (DLR

The Gaia-ESO Survey: Galactic evolution of sulphur and zinc

NASA Astrophysics Data System (ADS)

Duffau, S.; Caffau, E.; Sbordone, L.; Bonifacio, P.; Andrievsky, S.; Korotin, S.; Babusiaux, C.; Salvadori, S.; Monaco, L.; François, P.; Skúladóttir, Á.; Bragaglia, A.; Donati, P.; Spina, L.; Gallagher, A. J.; Ludwig, H.-G.; Christlieb, N.; Hansen, C. J.; Mott, A.; Steffen, M.; Zaggia, S.; Blanco-Cuaresma, S.; Calura, F.; Friel, E.; Jiménez-Esteban, F. M.; Koch, A.; Magrini, L.; Pancino, E.; Tang, B.; Tautvaišienė, G.; Vallenari, A.; Hawkins, K.; Gilmore, G.; Randich, S.; Feltzing, S.; Bensby, T.; Flaccomio, E.; Smiljanic, R.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Damiani, F.; Franciosini, E.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Morbidelli, L.; Sousa, S. G.; Worley, C. C.

2017-08-01

Context. Due to their volatile nature, when sulphur and zinc are observed in external galaxies, their determined abundances represent the gas-phase abundances in the interstellar medium. This implies that they can be used as tracers of the chemical enrichment of matter in the Universe at high redshift. Comparable observations in stars are more difficult and, until recently, plagued by small number statistics. Aims: We wish to exploit the Gaia-ESO Survey (GES) data to study the behaviour of sulphur and zinc abundances of a large number of Galactic stars, in a homogeneous way. Methods: By using the UVES spectra of the GES sample, we are able to assemble a sample of 1301 Galactic stars, including stars in open and globular clusters in which both sulphur and zinc were measured. Results: We confirm the results from the literature that sulphur behaves as an α-element. We find a large scatter in [Zn/Fe] ratios among giant stars around solar metallicity. The lower ratios are observed in giant stars at Galactocentric distances less than 7.5 kpc. No such effect is observed among dwarf stars, since they do not extend to that radius. Conclusions: Given the sample selection, giants and dwarfs are observed at different Galactic locations, and it is plausible, and compatible with simple calculations, that Zn-poor giants trace a younger population more polluted by SN Ia yields. It is necessary to extend observations in order to observe both giants and dwarfs at the same Galactic location. Further theoretical work on the evolution of zinc is also necessary. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 188.B-3002, 193.B-0936.The full table of S abundances is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/604/A128

Abundant molecular gas and inefficient star formation in intracluster regions: ram pressure stripped tail of the Norma galaxy ESO137-001

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jáchym, Pavel; Combes, Françoise; Cortese, Luca

For the first time, we reveal large amounts of cold molecular gas in a ram-pressure-stripped tail, out to a large 'intracluster' distance from the galaxy. With the Actama Pathfinder EXperiment (APEX) telescope, we have detected {sup 12}CO(2-1) emission corresponding to more than 10{sup 9} M {sub ☉} of H{sub 2} in three Hα bright regions along the tail of the Norma cluster galaxy ESO 137-001, out to a projected distance of 40 kpc from the disk. ESO 137-001 has an 80 kpc long and bright X-ray tail associated with a shorter (40 kpc) and broader tail of numerous star formingmore » H II regions. The amount of ∼1.5 × 10{sup 8} M {sub ☉} of H{sub 2} found in the most distant region is similar to molecular masses of tidal dwarf galaxies, though the standard Galactic CO-to-H{sub 2} factor could overestimate the H{sub 2} content. Along the tail, we find the amount of molecular gas to drop, while masses of the X-ray-emitting and diffuse ionized components stay roughly constant. Moreover, the amounts of hot and cold gas are large and similar, and together nearly account for the missing gas from the disk. We find a very low SFE (τ{sub dep} > 10{sup 10} yr) in the stripped gas in ESO 137-001 and suggest that this is due to a low average gas density in the tail, or turbulent heating of the interstellar medium that is induced by a ram pressure shock. The unprecedented bulk of observed H{sub 2} in the ESO 137-001 tail suggests that some stripped gas may survive ram pressure stripping in the molecular phase.« less

Fourteen Times the Earth

NASA Astrophysics Data System (ADS)

2004-08-01

ESO HARPS Instrument Discovers Smallest Ever Extra-Solar Planet Summary A European team of astronomers [1] has discovered the lightest known planet orbiting a star other than the sun (an "exoplanet"). The new exoplanet orbits the bright star mu Arae located in the southern constellation of the Altar. It is the second planet discovered around this star and completes a full revolution in 9.5 days. With a mass of only 14 times the mass of the Earth, the new planet lies at the threshold of the largest possible rocky planets, making it a possible super Earth-like object. Uranus, the smallest of the giant planets of the Solar System has a similar mass. However Uranus and the new exoplanet differ so much by their distance from the host star that their formation and structure are likely to be very different. This discovery was made possible by the unprecedented accuracy of the HARPS spectrograph on ESO's 3.6-m telescope at La Silla, which allows radial velocities to be measured with a precision better than 1 m/s. It is another clear demonstration of the European leadership in the field of exoplanet research. PR Photo 25a/04: The HARPS Spectrograph and the 3.6m Telescope PR Photo 25b/04: Observed Velocity Variation of mu Arae (3.6m/HARPS, 1.2m Swiss/CORALIE, AAT/UCLES) PR Photo 25c/04: Velocity Variation of mu Arae Observed by HARPS (3.6m/HARPS) PR Photo 25d/04: "Velocity Curve" of mu Arae A unique planet hunting machine ESO PR Photo 25a/04 ESO PR Photo 25a/04 The HARPS Spectrograph and the 3.6m Telescope [Preview - JPEG: 602 x 400 pix - 211k] [Normal - JPEG: 1202 x 800 pix - 645k] Caption: ESO PR Photo 25a/04 represents a montage of the HARPS spectrograph and the 3.6m telescope at La Silla. The upper left shows the dome of the telescope, while the upper right illustrates the telescope itself. The HARPS spectrograph is shown in the lower image during laboratory tests. The vacuum tank is open so that some of the high-precision components inside can be seen. Since the first

Dancing around the Black Hole

NASA Astrophysics Data System (ADS)

2001-08-01

, however, and will soon disrupt. At some moment, many of those young stars may get too close to the monster in the centre and suffer an unhappy fate... PR Photo 25a/01 : The active galaxy NGC 1097 (R-band image) PR Photo 25b/01 : The active galaxy NGC 1808 (H-band image) PR Photo 25c/01 : The active galaxy NGC 5728 (K-band image) PR Photo 25d/01 : Schematic drawing of the various structural components mentioned in the text. PR Photo 25e/01 : ISAAC spectrum (2.3 µm) of the central region of NGC 1808 PR Photo 25f/01 : Stellar motions at the centre of NGC 1808 Central black holes in galaxies ESO PR Photo 25a/01 ESO PR Photo 25a/01 [Preview - JPEG: 400 x 489 pix - 39k] [Normal - JPEG: 800 x 977 pix - 296k] ESO PR Photo 25b/01 ESO PR Photo 25b/01 [Preview - JPEG: 400 x 499 pix - 40k] [Normal - JPEG: 800 x 997 pix - 168k] ESO PR Photo 25c/01 ESO PR Photo 25c/01 [Preview - JPEG: 400 x 488 pix - 47k] [Normal - JPEG: 800 x 975 pix - 384k] Caption : Photos of three active galaxies that were observed with ISAAC during the present programme. They show NGC 1097 (R-band; Photo 25a/01) and the central areas of NGC 1808 (H-band; Photo 25b/01) and NGC 5728 (K-band; Photo 25c/01). The bar-like structures and the luminous centres where the Black Holes are located are well visible - they are discussed in the text. The distances to these galaxies are approximately 55, 35 and 120 million light-years, respectively; the local scales are indicated in the photos. Technical information about these photos is available below. Recent research with space- and ground-based astronomical telescopes indicate that there are very heavy Black Holes at the centres of most galaxies. There is also general agreement among scientists that many of the closest neighbours of our own Milky Way Galaxy, for example the large spiral Andromeda Galaxy and the peculiar Centaurus A galaxy (cf. ESO PR 04/01 ), do contain central black holes with masses from millions to billions of solar masses [2]. Black Holes have an

Curva de rotação óptica de ESO-LV 5100550

NASA Astrophysics Data System (ADS)

Carvalho, D. B.; Soares, D. S. L.

2003-08-01

ESO-LV 5100550 é o membro mais fraco do par de galáxias austral SBG 357 (Soares et al. 1995). É classificada no catálogo RC3 como uma espiral ordinária de tipo inicial (early-type); porém, uma análise morfológica sugere que ela tenha uma grande barra. O objetivo do estudo é determinar sua cinemática de tal modo que possamos inferir mais a respeito de sua dinâmica, provavelmente perturbada, já que se espera que esteja sob forte influência da companheira ESO-LV 5100560. Apresentarei resultados parciais determinados a partir de espectros obtidos com o instrumento Double Spectrograph montado no telescópio Hale do Monte Palomar, EUA. As observações foram realizadas por D.S.L. Soares, P.M.V. Veiga e T.E. Nordgren, em 1998. Foram tomados espectros de fenda longa posicionada sobre a linha dos nodos do disco e ao longo da suposta barra. Os dados foram reduzidos com uso do pacote IRAF. Obtivemos o perfil de velocidades radiais na linha de visada ao longo das fendas e calculamos o desvio para o vermelho cosmológico do sistema, com base no espectro central. Determinamos as curvas de rotação deprojetadas, com base em cálculos para os valores teóricos esperados das componentes de velocidades puramente circulares em um disco inclinado. A inclinação do disco, dado fundamental nesta deprojeção, foi estimada através da média das elipticidades das isofotas mais externas.

The ESO Diffuse Interstellar Band Large Exploration Survey (EDIBLES)

NASA Astrophysics Data System (ADS)

Cami, J.; Cox, N. L.; Farhang, A.; Smoker, J.; Elyajouri, M.; Lallement, R.; Bacalla, X.; Bhatt, N. H.; Bron, E.; Cordiner, M. A.; de Koter, A..; Ehrenfreund, P.; Evans, C.; Foing, B. H.; Javadi, A.; Joblin, C.; Kaper, L.; Khosroshahi, H. G.; Laverick, M.; Le Petit, F..; Linnartz, H.; Marshall, C. C.; Monreal-Ibero, A.; Mulas, G.; Roueff, E.; Royer, P.; Salama, F.; Sarre, P. J.; Smith, K. T.; Spaans, M.; van Loon, J. T..; Wade, G.

2018-03-01

The ESO Diffuse Interstellar Band Large Exploration Survey (EDIBLES) is a Large Programme that is collecting high-signal-to-noise (S/N) spectra with UVES of a large sample of O and B-type stars covering a large spectral range. The goal of the programme is to extract a unique sample of high-quality interstellar spectra from these data, representing different physical and chemical environments, and to characterise these environments in great detail. An important component of interstellar spectra is the diffuse interstellar bands (DIBs), a set of hundreds of unidentified interstellar absorption lines. With the detailed line-of-sight information and the high-quality spectra, EDIBLES will derive strong constraints on the potential DIB carrier molecules. EDIBLES will thus guide the laboratory experiments necessary to identify these interstellar “mystery molecules”, and turn DIBs into powerful diagnostics of their environments in our Milky Way Galaxy and beyond. We present some preliminary results showing the unique capabilities of the EDIBLES programme.

VLT Commissioning Data Now Publicly Available

NASA Astrophysics Data System (ADS)

1999-11-01

"First Light" was achieved in May 1998 for VLT ANTU , the first 8.2-m Unit Telescope at the Paranal Observatory ( ESO PR 06/98 ). Since then, thousands of detailed images and spectra of a great variety of celestial objects have been recorded with this major new research facility. While some of these were obtained for scientific programmes and were therefore directed towards specific research needs, others were made during the "Commissioning Phases" in 1998/99 for the two major astronomical instruments, FORS1 ( FO cal R educer and S pectrograph) and ISAAC ( I nfrared S pectrometer A nd A rray C amera). They were carried out in order to test thoroughly the performance of the telescope and its instruments before the new facility was handed over to the astronomers on April 1, 1999. The Commissioning data are accordingly of variable quality and, contrarily to the science data, normally not intensity calibrated. However, while some of these frames are short test exposures that mainly served to ascertain the image quality under various observing conditions, a substantial fraction still contains scientifically valuable data. 10 Gigabytes released As planned, and in order to facilitate the exploitation of this useful material, ESO has today released over 10 Gigabytes of ANTU Commissioning data (and some additional test data from before April 1, 1999), obtained in the various observing modes of FORS1 and ISAAC . They encompass a total of 2235 files and are now available to astronomers and other interested parties in the ESO Member States. Information about this release and on how to obtain the data on CD-ROM or in electronic form is now available via the Science Archive Facility website. A special page with the list of raw science data frames included in this release has been set up. Searches for specific data (e.g., by object, sky field, filter, time of observation; calibration files, etc.) can be made from the ESO Science Archive Data Products page. These Commissioning

Stellar family in crowded, violent neighbourhood proves to be surprisingly normal

NASA Astrophysics Data System (ADS)

2009-06-01

Using ESO's Very Large Telescope, astronomers have obtained one of the sharpest views ever of the Arches Cluster -- an extraordinary dense cluster of young stars near the supermassive black hole at the heart of the Milky Way. Despite the extreme conditions astronomers were surprised to find the same proportions of low- and high-mass young stars in the cluster as are found in more tranquil locations in our Milky Way. ESO PR Photo 21a/09 The Arches Cluster ESO PR Photo 21b/09 The Centre of the Milky Way ESO PR Photo 21c/09 Around the Arches Cluster ESO PR Video 21a/09 A voyage to the heart of the Milky Way The massive Arches Cluster is a rather peculiar star cluster. It is located 25 000 light-years away towards the constellation of Sagittarius (the Archer), and contains about a thousand young, massive stars, less than 2.5 million years old [1]. It is an ideal laboratory to study how massive stars are born in extreme conditions as it is close to the centre of our Milky Way, where it experiences huge opposing forces from the stars, gas and the supermassive black hole that reside there. The Arches Cluster is ten times heavier than typical young star clusters scattered throughout our Milky Way and is enriched with chemical elements heavier than helium. Using the NACO adaptive optics instrument on ESO's Very Large Telescope, located in Chile, astronomers scrutinised the cluster in detail. Thanks to adaptive optics, astronomers can remove most of the blurring effect of the atmosphere, and so the new NACO images of the Arches Cluster are even crisper than those obtained with telescopes in space. Observing the Arches Cluster is very challenging because of the huge quantities of absorbing dust between Earth and the Galactic Centre, which visible light cannot penetrate. This is why NACO was used to observe the region in near-infrared light. The new study confirms the Arches Cluster to be the densest cluster of massive young stars known. It is about three light-years across

Edge-on!

NASA Astrophysics Data System (ADS)

2007-08-01

Peering at Uranus's Rings as they Swing Edge-on to Earth for the First Time Since their Discovery in 1977 As Uranus coasts through a brief window of time when its rings are edge-on to Earth - a view of the planet we get only once every 42 years - astronomers peering at the rings with ESO's Very Large Telescope and other space or ground-based telescopes are getting an unprecedented view of the fine dust in the system, free from the glare of the bright rocky rings. They may even find a new moon or two. ESO PR Photo 37/07 ESO PR Photo 37/07 The Uranus System "ESO's VLT took data at the precise moment when the rings were edge-on to Earth," said Imke de Pater, of University of California, Berkeley who coordinated the worldwide campaign. She worked with two team members observing in Chile: Daphne Stam of the Technical University Delft in the Netherlands and Markus Hartung of ESO. The observations were done with NACO, one of the adaptive optics instruments installed at the VLT. With adaptive optics, it is possible to obtain images almost free from the blurring effect of the atmosphere. It is as if the 8.2-m telescope were observing from space. Observations were also done with the Keck telescope in Hawaii, the Hubble Space Telescope, and at the Palomar Observatory. "Using different telescopes around the world allows us to observe as much of the changes during the ring-plane crossing as possible: when Uranus sets as seen from the VLT, it can still be observed by the Keck," emphasised Stam. Uranus orbits the Sun in 84 years. Twice during a Uranian year, the rings appear edge-on to Earth for a brief period. The rings were discovered in 1977, so this is the first time for a Uranus ring-crossing to be observed from Earth. The advantage of observations at a ring-plane crossing is that it becomes possible to look at the rings from the shadowed or dark side. From that vantage point, the normally bright outer rings grow fainter because their centimetre- to metre-sized rocks obscure

A Strange Supernova with a Gamma-Ray Burst

NASA Astrophysics Data System (ADS)

1998-10-01

Important Observations with La Silla Telescopes Several articles appear today in the scientific journal Nature about the strange supernova SN 1998bw that exploded earlier this year in the spiral galaxy ESO184-G82 . These studies indicate that this event was linked to a Gamma-Ray Burst and may thus provide new insights into this elusive phenomenon. Important observations of SN 1998bw have been made with several astronomical telescopes at the ESO La Silla Observatory by some of the co-authors of the Nature articles [1]. The measurements at ESO will continue during the next years. The early observations On April 25, the BeppoSAX satellite detected a Gamma-Ray Burst from the direction of the constellation Telescopium, deep in the southern sky. Although there is now general consensus that they originate in very distant galaxies, the underlying physical causes of these events that release great amounts of energy within seconds are still puzzling astronomers. Immediately after reports about the April 25 Burst had been received, astronomers at La Silla took some images of the sky region where the gamma-rays were observed as a "Target of Opportunity" (ToO) programme. The aim was to check if the visual light of one of the objects in the field had perhaps brightened when compared to exposures made earlier. This would then provide a strong indication of the location of the Gamma-Ray Burst. The digital exposures were transferred to the Italian/Dutch group around BeppoSax that had requested these ToO observations. Astronomers of this group quickly noticed a new, comparatively bright star, right on the arm of a small spiral galaxy. This galaxy was first catalogued in the 1970's during the ESO/Uppsala Survey of the Southern Sky and received the designation ESO184-G82 . It is located at a distance of about 140 million light-years. SN 1998bw ESO PR Photo 39a/98 ESO PR Photo 39a/98 [Preview - JPEG: 800 x 963 pix - 592k] [High-Res - JPEG: 3000 x 3612 pix - 4.1Mb] ESO PR Photo 39b/98

Young and Exotic Stellar Zoo

NASA Astrophysics Data System (ADS)

2005-03-01

observations, astronomers infer that the Sun itself was born in one such cluster, some 4,500 million years ago. In some active ("starburst") galaxies, scientists have observed violent episodes of star formation (see, for example, ESO Press Photo 31/04), leading to the development of super star clusters, each containing several million stars. Such events were obviously common during the Milky Way's childhood, more than 12,000 million years ago: the many galactic globular clusters - which are nearly as old as our Galaxy (e.g. ESO PR 20/04) - are indeed thought to be the remnants of early super star clusters. All super star clusters so far observed in starburst galaxies are very distant. It is not possible to distinguish their individual stars, even with the most advanced technology. This dramatically complicates their study and astronomers have therefore long been eager to find such clusters in our neighbourhood in order to probe their structure in much more detail. Now, a team of European astronomers [1] has finally succeeded in doing so, using several of ESO's telescopes at the La Silla observatory (Chile). Westerlund 1 ESO PR Photo 09a/05 ESO PR Photo 09a/05 The Super Star Cluster Westerlund 1 (2.2m MPG/ESO + WFI) [Preview - JPEG: 400 x 472 pix - 58k] [Normal - JPEG: 800 x 943 pix - 986k] [Full Res - JPEG: 1261 x 1486 pix - 2.4M] Caption: ESO PR Photo 09a/05 is a composite image of the super star cluster "Westerlund 1" from 2.2-m MPG/ESO Wide-Field Imager (WFI) observations. The image covers a 5 x 5 arcmin sky region and is based on observations made in the V-band (550 nm, 2 min exposure time, associated to the blue channel), R-band (650nm, 1 min, green channel) and I-band (784nm, 18 sec, red channel). Only the central CCD of WFI was used, as the entire cluster fits comfortably inside it. The foreground stars appear blue, while the hot massive members of the cluster look orange, and the cool massive ones come out red. The open cluster Westerlund 1 is located in the Southern

Watching the Birth of a Galaxy Cluster?

NASA Astrophysics Data System (ADS)

1999-07-01

about 10,000 million light-years from the Earth (the redshift is 2.2), the VLT sees it as it was when the Universe was only about 20% of its present age. Previous observations of this galaxy by the same team of astronomers showed that its radio, X-ray and optical emission had many extreme characteristics that would be expected from a giant galaxy, forming at the centre of a rich cluster. However, because the galaxy is so distant, the cluster could not be seen directly. Radio data obtained by the Very Large Array (VLA) in the USA and X-ray data with the ROSAT satellite both indicated that the galaxy is surrounded by a hot gas similar to that observed at the centres of nearby rich clusters of galaxies. Most telling was a picture taken by the Hubble Space Telescope that revealed that the galaxy comprises a large number of clumps, and which bore a remarkable resemblance to computer models of the birth of giant galaxies in clusters. From these observations, it was concluded that 1138-262 is likely to be a massive galaxy in the final stage of assemblage through merging with many smaller galaxies in an infant rich cluster and the most distant known X-ray cluster. VLT obtains Lyman-alpha images ESO PR Photo 33a/99 ESO PR Photo 33a/99 [Preview - JPEG: 483 x 400 pix - 86k] [Normal - JPEG: 966 x 800 pix - 230k] [High-Res - JPEG: 2894 x 2396 pix - 1.1M] Caption to ESO PR Photo 33a/99 : False-colour picture of the ionized hydrogen gas surrounding 1138-262 (Lyman-alpha). The size of this cloud is about 5 times larger than the optical extent of the Milky Way Galaxy. A contour plot, as observed with VLT ANTU + FORS1 in a narrow-band filter around the wavelength of the redshifted Lyman-alpha line, is superposed on a false-colour representation of the same image. The contour levels are a geometric progression in steps of 2 1/2. The image has not been flux calibrated, so the first contour level is arbitrary. The field measures 35 x 25 arcsec 2 , corresponding to about 910,000 x 650

Operational metrics for the ESO Very Large Telescope: lessons learned and future steps

NASA Astrophysics Data System (ADS)

Primas, F.; Marteau, S.; Tacconi-Garman, L. E.; Mainieri, V.; Mysore, S.; Rejkuba, M.; Hilker, M.; Patat, F.; Sterzik, M.; Kaufer, A.; Mieske, S.

2016-07-01

When ESO's Very Large Telescope opened its first dome in April 1999 it was the first ground-based facility to offer to the scientific community access to an 8-10m class telescope with both classical and queue observing. The latter was considered to be the most promising way to ensure the observing flexibility necessary to execute the most demanding scientific programmes under the required, usually very well defined, conditions. Since then new instruments have become operational and 1st generation ones replaced, filling the 12 VLT foci and feeding the VLT Interferometer and its four Auxiliary Telescopes. Operating efficiently such a broad range of instruments installed and available every night of the year on four 8-metre telescopes offers many challenges. Although it may appear that little has changed since 1999, the underlying VLT operational model has evolved in order to accommodate different requirements from the user community and features of new instruments. Did it fulfil its original goal and, if so, how well? How did it evolve? What are the lessons learned after more than 15 years of operations? A careful analysis and monitoring of statistics and trends in Phase 1 and Phase 2 has been deployed under the DOME (Dashboard for Operational Metrics at ESO) project. The main goal of DOME is to provide robust metrics that can be followed with time in a user-friendly manner. Here, we summarize the main findings on the handling of service mode observations and present the most recent developments.

The Gaia-ESO Survey: double-, triple-, and quadruple-line spectroscopic binary candidates

NASA Astrophysics Data System (ADS)

Merle, T.; Van Eck, S.; Jorissen, A.; Van der Swaelmen, M.; Masseron, T.; Zwitter, T.; Hatzidimitriou, D.; Klutsch, A.; Pourbaix, D.; Blomme, R.; Worley, C. C.; Sacco, G.; Lewis, J.; Abia, C.; Traven, G.; Sordo, R.; Bragaglia, A.; Smiljanic, R.; Pancino, E.; Damiani, F.; Hourihane, A.; Gilmore, G.; Randich, S.; Koposov, S.; Casey, A.; Morbidelli, L.; Franciosini, E.; Magrini, L.; Jofre, P.; Costado, M. T.; Jeffries, R. D.; Bergemann, M.; Lanzafame, A. C.; Bayo, A.; Carraro, G.; Flaccomio, E.; Monaco, L.; Zaggia, S.

2017-12-01

Context. The Gaia-ESO Survey (GES) is a large spectroscopic survey that provides a unique opportunity to study the distribution of spectroscopic multiple systems among different populations of the Galaxy. Aims: Our aim is to detect binarity/multiplicity for stars targeted by the GES from the analysis of the cross-correlation functions (CCFs) of the GES spectra with spectral templates. Methods: We developed a method based on the computation of the CCF successive derivatives to detect multiple peaks and determine their radial velocities, even when the peaks are strongly blended. The parameters of the detection of extrema (DOE) code have been optimized for each GES GIRAFFE and UVES setup to maximize detection. The DOE code therefore allows to automatically detect multiple line spectroscopic binaries (SBn, n ≥ 2). Results: We apply this method on the fourth GES internal data release and detect 354 SBn candidates (342 SB2, 11 SB3, and even one SB4), including only nine SBs known in the literature. This implies that about 98% of these SBn candidates are new because of their faint visual magnitude that can reach V = 19. Visual inspection of the SBn candidate spectra reveals that the most probable candidates have indeed a composite spectrum. Among the SB2 candidates, an orbital solution could be computed for two previously unknown binaries: CNAME 06404608+0949173 (known as V642 Mon) in NGC 2264 and CNAME 19013257-0027338 in Berkeley 81 (Be 81). A detailed analysis of the unique SB4 (four peaks in the CCF) reveals that CNAME 08414659-5303449 (HD 74438) in the open cluster IC 2391 is a physically bound stellar quadruple system. The SB candidates belonging to stellar clusters are reviewed in detail to discard false detections. We suggest that atmospheric parameters should not be used for these system components; SB-specific pipelines should be used instead. Conclusions: Our implementation of an automatic detection of spectroscopic binaries within the GES has allowed the

A new mix of power for the ESO installations in Chile: greener, more reliable, cheaper

NASA Astrophysics Data System (ADS)

Filippi, G.; Tamai, R.; Kalaitzoglou, D.; Wild, W.; Delorme, A.; Rioseco, D.

2016-07-01

The highest sky quality demands for astronomical research impose to locate observatories often in areas not easily reached by the existing power infrastructures. At the same time, availability and cost of power is a primary factor for sustainable operations. Power may also be a potential source for CO2 pollution. As part of its green initiatives, ESO is in the process of replacing the power sources for its own, La Silla and Paranal-Armazones, and shared, ALMA, installations in Chile in order to provide them with more reliable, affordable, and smaller CO2 footprint power solutions. The connectivity to the Chilean interconnected power systems (grid) which is to extensively use Non-Conventional Renewable Energy (NCRE) as well as the use of less polluting fuels wherever self-generation cannot be avoided are key building blocks for the solutions selected for every site. In addition, considerations such as the environmental impact and - if required - the partnership with other entities have also to be taken into account. After years of preparatory work to which the Chilean Authorities provided great help and support, ESO has now launched an articulated program to upgrade the existing agreements/facilities in i) the La Silla Observatory, from free to regulated grid client status due to an agreement with a Solar Farm private initiative, in ii) the Paranal-Armazones Observatory, from local generation using liquefied petroleum gas (LPG) to connection to the grid which is to extensively use NCRE, and last but not least, in iii) the ALMA Observatory where ESO participates together with North American and East Asian partners, from replacing the LPG as fuel for the turbine local generation system with the use of less polluting natural gas (NG) supplied by a pipe connection to eliminate the pollution caused by the LPG trucks (currently 1 LPG truck from the VIII region, Bio Bio, to the II region, ALMA and back every day, for a total of 3000km). The technologies used and the status

Young and Waltzing Binary Stars

NASA Astrophysics Data System (ADS)

2001-10-01

ADONIS Observes Low-mass Eclipsing System in Orion Summary A series of very detailed images of a binary system of two young stars have been combined into a movie . In merely 3 days, the stars swing around each other. As seen from the earth, they pass in front of each other twice during a full revolution, producing eclipses during which their combined brightness diminishes . A careful analysis of the orbital motions has now made it possible to deduce the masses of the two dancing stars . Both turn out to be about as heavy as our Sun. But while the Sun is about 4500 million years old, these two stars are still in their infancy. They are located some 1500 light-years away in the Orion star-forming region and they probably formed just 10 million years ago . This is the first time such an accurate determination of the stellar masses could be achieved for a young binary system of low-mass stars . The new result provides an important piece of information for our current understanding of how young stars evolve. The observations were obtained by a team of astronomers from Italy and ESO [1] using the ADaptive Optics Near Infrared System (ADONIS) on the 3.6-m telescope at the ESO La Silla Observatory. PR Photo 29a/01 : The RXJ 0529.4+0041 system before primary eclipse PR Photo 29b/01 : The RXJ 0529.4+0041 system at mid-primary eclipse PR Photo 29c/01 : The RXJ 0529.4+0041 system after primary eclipse PR Photo 29d/01 : The RXJ 0529.4+0041 system before secondary eclipse PR Photo 29e/01 : The RXJ 0529.4+0041 system at mid-secondary eclipse PR Photo 29f/01 : The RXJ 0529.4+0041 system after secondary eclipse PR Video Clip 06/01 : Video of the RXJ 0529.4+0041 system Binary stars and stellar masses Since some time, astronomers have noted that most stars seem to form in binary or multiple systems. This is quite fortunate, as the study of binary stars is the only way in which it is possible to measure directly one of the most fundamental quantities of a star, its mass. The mass of a

The evolved central star of the planetary nebula ESO 166-PN 21.

NASA Astrophysics Data System (ADS)

Pena, M.; Ruiz, M. T.; Bergeron, P.; Torres-Peimbert, S.; Heathcote, S.

1997-02-01

Optical and UV spectrophotometric data of the nebula and the central star of the planetary nebula ESO 166-PN 21 are presented. The analysis of the nebular lines confirms that it is a He- and N-rich PN, with He/H=0.138+/-0.005 and N/O=0.58+/-0.08. The oxygen abundance is 12+logO/H=8.60+/-0.10. A distance of 1.2+/-0.2 kpc is derived for the nebula. The central star is very faint and blue, with an apparent magnitude V=17.94+/-0.03mag and a dereddened color index (B-V)_0_=-0.38mag. It shows faint wide H and He absorption lines typical of a DAO star. By modeling the line profiles we derived T_eff_=69200+/-8700K, logg=7.14+/-0.39 and logHe/H=-1.50+/-0.49 for the star. The position of the star in a HR diagram compared with evolutionary tracks indicates a stellar mass of ~0.55Msun_. The bolometric correction derived from the model atmosphere is -5.6mag which, combined with the mass, yields an absolute visual magnitude M_V_=6.95, a luminosity of 22Lsun_ and a distance of 1185+/-700pc, in good agreement with the nebular distance. Therefore, ESO 166-PN 21 central star is among the hottest and most helium-rich DAO stars and it is one of the most evolved PN nuclei known, similar to the central stars of S216 and NGC7293. A kinematical age of 16100yr is deduced for the nebula which is lower by about two orders of magnitude than the age of the central star. The possibility that this object is a member of a close binary system is suggested.

A Roof for ALMA

NASA Astrophysics Data System (ADS)

2007-03-01

On 10 March, an official ceremony took place on the 2,900m high site of the Atacama Large Millimeter/submillimeter Array (ALMA) Operations Support Facility, from where the ALMA antennas will be remotely controlled. The ceremony marked the completion of the structural works, while the building itself will be finished by the end of the year. This will become the operational centre of one of the most important ground-based astronomical facilities on Earth. ESO PR Photo 13a/07 ESO PR Photo 13a/07 Cutting the Red Ribbon The ceremony, known as 'Tijerales' in Chile, is the equivalent to the 'roof-topping ceremony' that takes place worldwide, in one form or another, to celebrate reaching the highest level of a construction. It this case, the construction is the unique ALMA Operations Support Facility (OSF), located near the town of San Pedro de Atacama. "The end of this first stage represents an historic moment for ALMA," said Hans Rykaczewski, the European ALMA Project Manager. "Once completed in December 2007, this monumental building of 7,000 square metres will be one of the largest and most important astronomical operation centres in the world." ALMA, located at an elevation of 5,000m in the Atacama Desert of northern Chile, will provide astronomers with the world's most advanced tool for exploring the Universe at millimetre and submillimetre wavelengths. ALMA will detect fainter objects and be able to produce much higher-quality images at these wavelengths than any previous telescope system. The OSF buildings are designed to suit the requirements of this exceptional observatory in a remote, desert location. The facility, which will host about 100 people during operations, consists of three main buildings: the technical building, hosting the control centre of the observatory, the antenna assembly building, including four antenna foundations for testing and maintenance purposes, and the warehouse building, including mechanical workshops. Further secondary buildings are

Observing multiple populations in globular clusters with the ESO archive: NGC 6388 reloaded

NASA Astrophysics Data System (ADS)

Carretta, Eugenio; Bragaglia, Angela

2018-06-01

The metal-rich and old bulge globular cluster (GC) NGC 6388 is one of the most massive Galactic GCs (M 106 M⊙). However, the spectroscopic properties of its multiple stellar populations rested only on 32 red giants (only 7 of which observed with UVES, the others with GIRAFFE), given the difficulties in observing a rather distant cluster, heavily contaminated by bulge and disc field stars. We bypassed the problem using the resources of the largest telescope facility ever: the European Southern Observatory (ESO) archive. By selecting member stars identified by other programmes, we derive atmospheric parameters and the full set of abundances for 15 species from high-resolution UVES spectra of another 17 red giant branch stars in NGC 6388. We confirm that no metallicity dispersion is detectable in this GC. About 30% of the stars show the primordial composition of first-generation stars, about 20% present an extremely modified second-generation composition, and 50% have an intermediate composition. The stars are clearly distributed in the Al-O and Na-O planes in three discrete groups. We find substantial hints that more than a single class of polluters is required to reproduce the composition of the intermediate component in NGC 6388. In the heavily polluted component the sum Mg+Al increases as Al increases. The sum Mg+Al+Si is constant, and is the fossil record of hot H-burning at temperatures higher than about 70 MK in the first-generation polluters that contributed to form multiple populations in this cluster. Based on observations collected at ESO telescopes under programmes 073.D-0211 (propr ietary), and 073.D-0760, 381.D-0329, 095.D-0834 (archival).

Detection and Tracking of NY-ESO-1-Specific CD8+ T Cells by High-Throughput T Cell Receptor β (TCRB) Gene Rearrangements Sequencing in a Peptide-Vaccinated Patient.

PubMed

Miyai, Manami; Eikawa, Shingo; Hosoi, Akihiro; Iino, Tamaki; Matsushita, Hirokazu; Isobe, Midori; Uenaka, Akiko; Udono, Heiichiro; Nakajima, Jun; Nakayama, Eiichi; Kakimi, Kazuhiro

2015-01-01

Comprehensive immunological evaluation is crucial for monitoring patients undergoing antigen-specific cancer immunotherapy. The identification and quantification of T cell responses is most important for the further development of such therapies. Using well-characterized clinical samples from a high responder patient (TK-f01) in an NY-ESO-1f peptide vaccine study, we performed high-throughput T cell receptor β-chain (TCRB) gene next generation sequencing (NGS) to monitor the frequency of NY-ESO-1-specific CD8+ T cells. We compared these results with those of conventional immunological assays, such as IFN-γ capture, tetramer binding and limiting dilution clonality assays. We sequenced human TCRB complementarity-determining region 3 (CDR3) rearrangements of two NY-ESO-1f-specific CD8+ T cell clones, 6-8L and 2F6, as well as PBMCs over the course of peptide vaccination. Clone 6-8L possessed the TCRB CDR3 gene TCRBV11-03*01 and BJ02-01*01 with amino acid sequence CASSLRGNEQFF, whereas 2F6 possessed TCRBV05-08*01 and BJ02-04*01 (CASSLVGTNIQYF). Using these two sequences as models, we evaluated the frequency of NY-ESO-1-specific CD8+ T cells in PBMCs ex vivo. The 6-8L CDR3 sequence was the second most frequent in PBMC and was present at high frequency (0.7133%) even prior to vaccination, and sustained over the course of vaccination. Despite a marked expansion of NY-ESO-1-specific CD8+ T cells detected from the first through 6th vaccination by tetramer staining and IFN-γ capture assays, as evaluated by CDR3 sequencing the frequency did not increase with increasing rounds of peptide vaccination. By clonal analysis using 12 day in vitro stimulation, the frequency of B*52:01-restricted NY-ESO-1f peptide-specific CD8+ T cells in PBMCs was estimated as only 0.0023%, far below the 0.7133% by NGS sequencing. Thus, assays requiring in vitro stimulation might be underestimating the frequency of clones with lower proliferation potential. High-throughput TCRB sequencing using NGS

Detection and Tracking of NY-ESO-1-Specific CD8+ T Cells by High-Throughput T Cell Receptor β (TCRB) Gene Rearrangements Sequencing in a Peptide-Vaccinated Patient

PubMed Central

Miyai, Manami; Eikawa, Shingo; Hosoi, Akihiro; Iino, Tamaki; Matsushita, Hirokazu; Isobe, Midori; Uenaka, Akiko; Udono, Heiichiro; Nakajima, Jun; Nakayama, Eiichi; Kakimi, Kazuhiro

2015-01-01

Comprehensive immunological evaluation is crucial for monitoring patients undergoing antigen-specific cancer immunotherapy. The identification and quantification of T cell responses is most important for the further development of such therapies. Using well-characterized clinical samples from a high responder patient (TK-f01) in an NY-ESO-1f peptide vaccine study, we performed high-throughput T cell receptor β-chain (TCRB) gene next generation sequencing (NGS) to monitor the frequency of NY-ESO-1-specific CD8+ T cells. We compared these results with those of conventional immunological assays, such as IFN-γ capture, tetramer binding and limiting dilution clonality assays. We sequenced human TCRB complementarity-determining region 3 (CDR3) rearrangements of two NY-ESO-1f-specific CD8+ T cell clones, 6-8L and 2F6, as well as PBMCs over the course of peptide vaccination. Clone 6-8L possessed the TCRB CDR3 gene TCRBV11-03*01 and BJ02-01*01 with amino acid sequence CASSLRGNEQFF, whereas 2F6 possessed TCRBV05-08*01 and BJ02-04*01 (CASSLVGTNIQYF). Using these two sequences as models, we evaluated the frequency of NY-ESO-1-specific CD8+ T cells in PBMCs ex vivo. The 6-8L CDR3 sequence was the second most frequent in PBMC and was present at high frequency (0.7133%) even prior to vaccination, and sustained over the course of vaccination. Despite a marked expansion of NY-ESO-1-specific CD8+ T cells detected from the first through 6th vaccination by tetramer staining and IFN-γ capture assays, as evaluated by CDR3 sequencing the frequency did not increase with increasing rounds of peptide vaccination. By clonal analysis using 12 day in vitro stimulation, the frequency of B*52:01-restricted NY-ESO-1f peptide-specific CD8+ T cells in PBMCs was estimated as only 0.0023%, far below the 0.7133% by NGS sequencing. Thus, assays requiring in vitro stimulation might be underestimating the frequency of clones with lower proliferation potential. High-throughput TCRB sequencing using NGS

Biggest Star in Our Galaxy Sits within a Rugby-Ball Shaped Cocoon

NASA Astrophysics Data System (ADS)

2003-11-01

VLT Interferometer Gives Insight Into the Shape of Eta Carinae Summary Ever since 1841, when the until then inconspicuous southern star Eta Carinae underwent a spectacular outburst, astronomers have wondered what exactly is going on in this unstable giant star. However, due to its considerable distance - 7,500 light-years - details of the star itself were beyond observation. This star is known to be surrounded by the Homunculus Nebula , two mushroom-shaped clouds ejected by the star, each of which is hundreds of times larger than our solar system. Now, for the first time, infrared interferometry with the VINCI instrument on ESO's Very Large Telescope Interferometer (VLTI) enabled an international team of astronomers [1] to zoom-in on the inner part of its stellar wind. For Roy van Boekel , leader of the team, these results indicate that " the wind of Eta Carinae turns out to be extremely elongated and the star itself is highly unstable because of its fast rotation." PR Photo 32a/03 : The Immediate Surroundings of Eta Carinae (NAOS-CONICA/YEPUN). PR Photo 32b/03 : The Highly Unstable Star Eta Carinae (Artist's Impression) A monster in the southern sky ESO PR Photo 32a/03 ESO PR Photo 32a/03 [Preview - JPEG: 549 x 400 pix - 60k [Normal - JPEG: 1098 x 800 pix - 566k] Caption : The image to the left in PR Photo 32a/03 shows the mushroom-shaped clouds, known as the Homunculus Nebula , that surround the massive star Eta Carinae (Credit: NASA/ESA HST). To the right is an image obtained with the VLT NACO adaptive-optics camera that reveals the structure of the star's immediate surroundings. The central region displays a complex morphology of luminous objects. Eta Carinae , the most luminous star known in our Galaxy, is by all standards a real monster: it is 100 times more massive than our Sun and 5 million times as luminous. This star has now entered the final stage of its life and is highly unstable. It undergoes giant outbursts from time to time; one of the most recent

Chandra and the VLT Jointly Investigate the Cosmic X-Ray Background

NASA Astrophysics Data System (ADS)

2001-03-01

Summary Important scientific advances often happen when complementary investigational techniques are brought together . In the present case, X-ray and optical/infrared observations with some of the world's foremost telescopes have provided the crucial information needed to solve a 40-year old cosmological riddle. Very detailed observations of a small field in the southern sky have recently been carried out, with the space-based NASA Chandra X-Ray Observatory as well as with several ground-based ESO telescopes, including the Very Large Telescope (VLT) at the Paranal Observatory (Chile). Together, they have provided the "deepest" combined view at X-ray and visual/infrared wavelengths ever obtained into the distant Universe. The concerted observational effort has already yielded significant scientific results. This is primarily due to the possibility to 'identify' most of the X-ray emitting objects detected by the Chandra X-ray Observatory on ground-based optical/infrared images and then to determine their nature and distance by means of detailed (spectral) observations with the VLT . In particular, there is now little doubt that the so-called 'X-ray background' , a seemingly diffuse short-wave radiation first detected in 1962, in fact originates in a vast number of powerful black holes residing in active nuclei of distant galaxies . Moreover, the present investigation has permitted to identify and study in some detail a prime example of a hitherto little known type of object, a distant, so-called 'Type II Quasar' , in which the central black hole is deeply embedded in surrounding gas and dust. These achievements are just the beginning of a most fruitful collaboration between "space" and "ground". It is yet another impressive demonstration of the rapid progress of modern astrophysics, due to the recent emergence of a new generation of extremely powerful instruments. PR Photo 09a/01 : Images of a small part of the Chandra Deep Field South , obtained with ESO telescopes

Near-InfraRed Planet Searcher to Join HARPS on the ESO 3.6-metre Telescope

NASA Astrophysics Data System (ADS)

Bouchy, F.; Doyon, R.; Artigau, É.; Melo, C.; Hernandez, O.; Wildi, F.; Delfosse, X.; Lovis, C.; Figueira, P.; Canto Martins, B. L..; González Hernández, J. I..; Thibault, S.; Reshetov, V.; Pepe, F.; Santos, N. C.; de Medeiros, J. R..; Rebolo, R.; Abreu, M.; Adibekyan, V. Z.; Bandy, T.; Benz, W.; Blind, N.; Bohlender, D.; Boisse, I.; Bovay, S.; Broeg, C.; Brousseau, D.; Cabral, A.; Chazelas, B.; Cloutier, R.; Coelho, J.; Conod, U.; Cumming, A.; Delabre, B.; Genolet, L.; Hagelberg, J.; Jayawardhana, R.; Käufl, H.-U.; Lafrenière, D.; de Castro Leão, I..; Malo, L.; de Medeiros Martins, A..; Matthews, J. M.; Metchev, S.; Oshagh, M.; Ouellet, M.; Parro, V. C.; Rasilla Piñeiro, J. L..; Santos, P.; Sarajlic, M.; Segovia, A.; Sordet, M.; Udry, S.; Valencia, D.; Vallée, P.; Venn, K.; Wade, G. A.; Saddlemyer, L.

2017-09-01

The Near-InfraRed Planet Searcher (NIRPS) is a new ultra-stable infrared (YJH) spectrograph that will be installed on ESO's 3.6-metre Telescope in La Silla, Chile. Aiming to achieve a precision of 1 m s-1, NIRPS is designed to find rocky planets orbiting M dwarfs, and will operate together with the High Accuracy Radial velocity Planet Searcher (HARPS), also on the 3.6-metre Telescope. In this article we describe the NIRPS science cases and present its main technical characteristics.

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

PubMed

Sevillano, Alejandro M; Fernández-Borges, Natalia; Younas, Neelam; Wang, Fei; R Elezgarai, Saioa; Bravo, Susana; Vázquez-Fernández, Ester; Rosa, Isaac; Eraña, Hasier; Gil, David; Veiga, Sonia; Vidal, Enric; Erickson-Beltran, Melissa L; Guitián, Esteban; Silva, Christopher J; Nonno, Romolo; Ma, Jiyan; Castilla, Joaquín; R Requena, Jesús

2018-01-01

Very solid evidence suggests that the core of full length PrPSc is a 4-rung β-solenoid, and that individual PrPSc subunits stack to form amyloid fibers. We recently used limited proteolysis to map the β-strands and connecting loops that make up the PrPSc solenoid. Using high resolution SDS-PAGE followed by epitope analysis, and mass spectrometry, we identified positions ~116/118, 133-134, 141, 152-153, 162, 169 and 179 (murine numbering) as Proteinase K (PK) cleavage sites in PrPSc. Such sites likely define loops and/or borders of β-strands, helping us to predict the threading of the β-solenoid. We have now extended this approach to recombinant PrPSc (recPrPSc). The term recPrPSc refers to bona fide recombinant prions prepared by PMCA, exhibiting infectivity with attack rates of ~100%. Limited proteolysis of mouse and bank vole recPrPSc species yielded N-terminally truncated PK-resistant fragments similar to those seen in brain-derived PrPSc, albeit with varying relative yields. Along with these fragments, doubly N- and C-terminally truncated fragments, in particular ~89/97-152, were detected in some recPrPSc preparations; similar fragments are characteristic of atypical strains of brain-derived PrPSc. Our results suggest a shared architecture of recPrPSc and brain PrPSc prions. The observed differences, in particular the distinct yields of specific PK-resistant fragments, are likely due to differences in threading which result in the specific biochemical characteristics of recPrPSc. Furthermore, recombinant PrPSc offers exciting opportunities for structural studies unachievable with brain-derived PrPSc.

Solar Power at Play

NASA Astrophysics Data System (ADS)

2007-03-01

For the very first time, astronomers have witnessed the speeding up of an asteroid's rotation, and have shown that it is due to a theoretical effect predicted but never seen before. The international team of scientists used an armada of telescopes to discover that the asteroid's rotation period currently decreases by 1 millisecond every year, as a consequence of the heating of the asteroid's surface by the Sun. Eventually it may spin faster than any known asteroid in the solar system and even break apart. ESO PR Photo 11a/07 ESO PR Photo 11a/07 Asteroid 2000 PH5 "The Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) effect is believed to alter the way small bodies in the Solar System rotate," said Stephen Lowry (Queens University Belfast, UK), lead-author of one of the two companion papers in which this work is reported [1, 2]. "The warming caused by sunlight hitting the surfaces of asteroids and meteoroids leads to a gentle recoil effect as the heat is released," he added. "By analogy, if one were to shine light on a propeller over a long enough period, it would start spinning." Although this is an almost immeasurably weak force, its effect over millions of years is far from negligible. Astronomers believe the YORP effect may be responsible for spinning some asteroids up so fast that they break apart, perhaps leading to the formation of double asteroids. Others may be slowed down so that they take many days to complete a full turn. The YORP effect also plays an important role in changing the orbits of asteroids between Mars and Jupiter, including their delivery to planet-crossing orbits, such as those of near-Earth asteroids. Despite its importance, the effect has never been seen acting on a solar system body, until now. Using extensive optical and radar imaging from powerful Earth-based observatories, astronomers have directly observed the YORP effect in action on a small near-Earth asteroid, known as (54509) 2000 PH5. Shortly after its discovery in 2000, it was

The Gaia-ESO Survey: Exploring the complex nature and origins of the Galactic bulge populations

NASA Astrophysics Data System (ADS)

Rojas-Arriagada, A.; Recio-Blanco, A.; de Laverny, P.; Mikolaitis, Š.; Matteucci, F.; Spitoni, E.; Schultheis, M.; Hayden, M.; Hill, V.; Zoccali, M.; Minniti, D.; Gonzalez, O. A.; Gilmore, G.; Randich, S.; Feltzing, S.; Alfaro, E. J.; Babusiaux, C.; Bensby, T.; Bragaglia, A.; Flaccomio, E.; Koposov, S. E.; Pancino, E.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Damiani, F.; Donati, P.; Franciosini, E.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Lind, K.; Magrini, L.; Morbidelli, L.; Sacco, G. G.; Worley, C. C.; Zaggia, S.

2017-05-01

Context. As observational evidence steadily accumulates, the nature of the Galactic bulge has proven to be rather complex: the structural, kinematic, and chemical analyses often lead to contradictory conclusions. The nature of the metal-rich bulge - and especially of the metal-poor bulge - and their relation with other Galactic components, still need to be firmly defined on the basis of statistically significant high-quality data samples. Aims: We used the fourth internal data release of the Gaia-ESO survey to characterize the bulge metallicity distribution function (MDF), magnesium abundance, spatial distribution, and correlation of these properties with kinematics. Moreover, the homogeneous sampling of the different Galactic populations provided by the Gaia-ESO survey allowed us to perform a comparison between the bulge, thin disk, and thick disk sequences in the [Mg/Fe] vs. [Fe/H] plane in order to constrain the extent of their eventual chemical similarities. Methods: We obtained spectroscopic data for 2500 red clump stars in 11 bulge fields, sampling the area -10° ≤ l ≤ + 8° and -10° ≤ b ≤ -4° from the fourth internal data release of the Gaia-ESO survey. A sample of 6300 disk stars was also selected for comparison. Spectrophotometric distances computed via isochrone fitting allowed us to define a sample of stars likely located in the bulge region. Results: From a Gaussian mixture models (GMM) analysis, the bulge MDF is confirmed to be bimodal across the whole sampled area. The relative ratio between the two modes of the MDF changes as a function of b, with metal-poor stars dominating at high latitudes. The metal-rich stars exhibit bar-like kinematics and display a bimodality in their magnitude distribution, a feature which is tightly associated with the X-shape bulge. They overlap with the metal-rich end of the thin disk sequence in the [Mg/Fe] vs. [Fe/H] plane. On the other hand, metal-poor bulge stars have a more isotropic hot kinematics and do

The Toucan's Diamond

NASA Astrophysics Data System (ADS)

2006-06-01

The Southern constellation Tucana (the Toucan) is probably best known as the home of the Small Magellanic Cloud, one of the satellite galaxies of the Milky Way. But Tucana also hosts another famous object that shines thousands of lights, like a magnificent, oversized diamond in the sky: the globular cluster 47 Tucanae. More popularly known as 47 Tuc, it is surpassed in size and brightness by only one other globular cluster, Omega Centauri. Globular clusters are gigantic families of stars, comprising several tens of thousands of stars, all thought to be born at the same time from the same cloud of gas [1]. As such, they constitute unique laboratories for the study of how stars evolve and interact. This is even more so because they are located at the same distance, so the brightness of different types of stars, at different stages in their evolution can be directly compared. The stars in globular clusters are held together by their mutual gravity which gives them their spherical shape, hence their name. Globular clusters are thought to be among the oldest objects in our Milky Way galaxy, and contain therefore mostly old, low-mass stars. ESO PR Photo 20/06 ESO PR Photo 20/06 Globular Cluster 47 Tuc 47 Tucanae is an impressive globular cluster that is visible with the unaided eye from the southern hemisphere. It was discovered in 1751 by the French astronomer Nicholas Louis de Lacaille who cataloged it in his list of southern nebulous objects. Located about 16 000 light years away, it has a total mass of about 1 million times the mass of the Sun and is 120 light years across, making it appear on the sky as big as the full moon. The colour image of 47 Tucanae presented here was taken with FORS1 on ESO's Very Large Telescope in 2001. The image covers only the densest, very central part of the cluster. The globular cluster extends in reality four times further away! As can be seen however, the density of stars rapidly drops off when moving away from the centre. The red

Decision support tools for proton therapy ePR: intelligent treatment planning navigator and radiation toxicity tool for evaluating of prostate cancer treatment

NASA Astrophysics Data System (ADS)

Le, Anh H.; Deshpande, Ruchi; Liu, Brent J.

2010-03-01

The electronic patient record (ePR) has been developed for prostate cancer patients treated with proton therapy. The ePR has functionality to accept digital input from patient data, perform outcome analysis and patient and physician profiling, provide clinical decision support and suggest courses of treatment, and distribute information across different platforms and health information systems. In previous years, we have presented the infrastructure of a medical imaging informatics based ePR for PT with functionality to accept digital patient information and distribute this information across geographical location using Internet protocol. In this paper, we present the ePR decision support tools which utilize the imaging processing tools and data collected in the ePR. The two decision support tools including the treatment plan navigator and radiation toxicity tool are presented to evaluate prostate cancer treatment to improve proton therapy operation and improve treatment outcomes analysis.

Milky Way's super-efficient particle accelerators caught in the act

NASA Astrophysics Data System (ADS)

2009-06-01

Thanks to a unique "ballistic study" that combines data from ESO's Very Large Telescope and NASA's Chandra X-ray Observatory, astronomers have now solved a long-standing mystery of the Milky Way's particle accelerators. They show in a paper published today on Science Express that cosmic rays from our galaxy are very efficiently accelerated in the remnants of exploded stars. ESO PR Photo 23a/09 The rim of RCW 86 ESO PR Photo 23b/09 DSS + insert, annotated ESO PR Photo 23c/09 DSS image ESO PR Video 23a/09 Zoom-in RCW 86 During the Apollo flights astronauts reported seeing odd flashes of light, visible even with their eyes closed. We have since learnt that the cause was cosmic rays -- extremely energetic particles from outside the Solar System arriving at the Earth, and constantly bombarding its atmosphere. Once they reach Earth, they still have sufficient energy to cause glitches in electronic components. Galactic cosmic rays come from sources inside our home galaxy, the Milky Way, and consist mostly of protons moving at close to the speed of light, the "ultimate speed limit" in the Universe. These protons have been accelerated to energies exceeding by far the energies that even CERN's Large Hadron Collider will be able to achieve. "It has long been thought that the super-accelerators that produce these cosmic rays in the Milky Way are the expanding envelopes created by exploded stars, but our observations reveal the smoking gun that proves it", says Eveline Helder from the Astronomical Institute Utrecht of Utrecht University in the Netherlands, the first author of the new study. "You could even say that we have now confirmed the calibre of the gun used to accelerate cosmic rays to their tremendous energies", adds collaborator Jacco Vink, also from the Astronomical Institute Utrecht. For the first time Helder, Vink and colleagues have come up with a measurement that solves the long-standing astronomical quandary of whether or not stellar explosions produce enough

Different structural stability and toxicity of PrP(ARR) and PrP(ARQ) sheep prion protein variants.

PubMed

Paludi, Domenico; Thellung, Stefano; Chiovitti, Katia; Corsaro, Alessandro; Villa, Valentina; Russo, Claudio; Ianieri, Adriana; Bertsch, Uwe; Kretzschmar, Hans A; Aceto, Antonio; Florio, Tullio

2007-12-01

The polymorphisms at amino acid residues 136, 154, and 171 in ovine prion protein (PrP) have been associated with different susceptibility to scrapie: animals expressing PrP(ARQ) [PrP(Ala136/Arg154/Gln171)] show vulnerability, whereas those that express PrP(ARR) [PrP(Ala136/Arg154/Arg171)] are resistant to scrapie. The aim of this study was to evaluate the in vitro toxic effects of PrP(ARR) and PrP(ARQ) variants in relation with their structural characteristics. We show that both peptides cause cell death inducing apoptosis but, unexpectedly, the scrapie resistant PrP(ARR) form was more toxic than the scrapie susceptible PrP(ARQ) variant. Moreover, the alpha-helical conformation of PrP(ARR) was less stable than that of PrP(ARQ) and the structural determinants responsible of these different conformational stabilities were characterized by spectroscopic analysis. We observed that PrP toxicity was inversely related to protein structural stability, being the unfolded conformation more toxic than the native one. However, the PrP(ARQ) variant displays a higher propensity to form large aggregates than PrP(ARR). Interestingly, in the presence of small amounts of PrP(ARR), PrP(ARQ) aggregability was reduced to levels similar to that of PrP(ARR). Thus, in contrast to PrP(ARR) toxicity, scrapie transmissibility seems to reside in the more stable conformation of PrP(ARQ) that allows the formation of large amyloid fibrils.

Hi Image Synthesis of Southern Compact Groups

NASA Astrophysics Data System (ADS)

Babic, B.; Price, R. M.; Jones, K.

Four southern compact groups, the Hickson Compact Groups HCG 22 and HCG 26 (Hickson 1982), and the groups AM 1238 - 396 and ESO 410-G(024 - 026) have been imaged in Hi, along with 12 cm continuum using the Australia Telescope Compact Array (ATCA). The initial findings for the latter two groups are presented here. While ESO 410-G is not in fact a physical group, due to the discordant redshifts amongst the members, it is however presented here. Overall for all the groups we find no other sources of Hi in the field that might indicate that these are part of a larger loose group structure. This is not always the case, as with HCG 23 (Williams 1995) and HCG 95 (Hutchmeier 1999), both of whom find additional Hi sources within the primary beam accordant with the compact group's velocity. The Hi is also clearly associated with each of the individual member galaxies in all cases, except for HCG 26, which envelopes the whole group as was also shown by Williams and van Gorkom (Williams 1995).

Dynamic compressive behavior of Pr-Nd alloy at high strain rates and temperatures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang Huanran; Cai Canyuan; Chen Danian

2012-07-01

Based on compressive tests, static on 810 material test system and dynamic on the first compressive loading in split Hopkinson pressure bar (SHPB) tests for Pr-Nd alloy cylinder specimens at high strain rates and temperatures, this study determined a J-C type [G. R. Johnson and W. H. Cook, in Proceedings of Seventh International Symposium on Ballistics (The Hague, The Netherlands, 1983), pp. 541-547] compressive constitutive equation of Pr-Nd alloy. It was recorded by a high speed camera that the Pr-Nd alloy cylinder specimens fractured during the first compressive loading in SHPB tests at high strain rates and temperatures. From highmore » speed camera images, the critical strains of the dynamic shearing instability for Pr-Nd alloy in SHPB tests were determined, which were consistent with that estimated by using Batra and Wei's dynamic shearing instability criterion [R. C. Batra and Z. G. Wei, Int. J. Impact Eng. 34, 448 (2007)] and the determined compressive constitutive equation of Pr-Nd alloy. The transmitted and reflected pulses of SHPB tests for Pr-Nd alloy cylinder specimens computed with the determined compressive constitutive equation of Pr-Nd alloy and Batra and Wei's dynamic shearing instability criterion could be consistent with the experimental data. The fractured Pr-Nd alloy cylinder specimens of compressive tests were investigated by using 3D supper depth digital microscope and scanning electron microscope.« less

Irish Team Wins SEA & SPACE Super Prize

NASA Astrophysics Data System (ADS)

1998-09-01

A secondary school team from Ireland has won a trip to Europe's Spaceport in Kourou, French Guyana, and to ESO's Very Large Telescope (VLT) at Cerro Paranal, Chile. The trip is the Super-Prize for the Sea & Space Newspaper Competition , organised within the framework of the European Week for Scientific and Technological Culture. ESO PR Photo 33/98 ESO PR Photo 33/98 [Preview - JPEG: 800 x 434 pix - 568k] [High-Res - JPEG: 3000 x 1627 pix - 6.7Mb] The presentation of prize certificates to the winning Irish team (right) in Lisbon, on August 31, 1998, by ESO, ESA and EAAE representatives. Stephen Kearney, Cian Wilson (both aged 16 years), Eamonn McKeogh (aged 17 years) together with their teacher, John Daly of Blackrock College in Dublin, prepared their newspaper, Infinitus , on marine and space themes, and came first in the national round of the competition. Together with other students from all over Europe, they were invited to present their winning newspaper to a jury consisting of representatives of the organisers, during a special programme of events at the Gulbenkian Planetarium and EXPO '98 in Lisbon, from 28-31 August, 1998. The Irish team scored highly in all categories of the judging, which included scientific content and originality and creativity of the articles. Their look at Irish contributions to sea and space research also proved popular in a ballot by fellow student competitors. This vote was also taken into account by the judges. The jury was very impressed by the high quality of the national entries and there were several close runners-up. The width and depth was amazing and the variety of ideas and formats presented by the sixteen teams was enormous. A poster competition was organised for younger students, aged 10 to 13 and winning entries at national level are on display at the Oceanophilia Pavilion at EXPO '98. The SEA & SPACE project is a joint initiative of the European Space Agency (ESA) , the European Southern Observatory (ESO) , and the

Enhanced broadband near-infrared luminescence from Pr3+-doped tellurite glass with silver nanoparticles

NASA Astrophysics Data System (ADS)

Cheng, Pan; Zhou, Yaxun; Zhou, Minghan; Su, Xiue; Zhou, Zizhong; Yang, Gaobo

2017-11-01

Pr3+-doped tellurite glasses containing metallic silver NPs were synthesized by the conventional melt-quenching technique. Structural, thermal and optical properties of the synthesized glass samples were characterized by X-Ray diffraction (XRD) curves, Raman spectra, differential scanning calorimeter (DSC) curves, transmission electron microscopy (TEM) images, UV/Vis/NIR absorption and near-infrared fluorescence emission spectra. The XRD curves confirmed the amorphous structural nature of the synthesized glasses, the Raman spectra identified the presence of different vibrational groups, the DSC curves verified the good thermal stability, and the TEM images revealed the nucleated silver NPs with average diameter about 10 nm dispersed in the glass matrix and its surface Plasmon resonance (SPR) absorption band was located at around 510 nm. Besides, Judd-Ofelt intensity parameters Ωt (t = 2, 4, 6) and other important spectroscopic parameters like transition probability, radiative lifetime, branching ratio were calculated to evaluate the radiative properties of Pr3+ levels from the measured optical absorption spectra. It was found that Pr3+-doped tellurite glasses could emit an ultra-broadband fluorescence extending from 1250 to 1650 nm under the 488 nm excitation, and this fluorescence emission increased further with the introduction of silver NPs. The enhanced fluorescence was mainly attributed to the increased local electric field around Pr3+ induced by silver NPs. The present results demonstrate that Pr3+-Ag codoped tellurite glass is a promising candidate for the near-infrared band ultra-broadband fiber amplifiers covering the expanded low-loss communication window.

Stellar Firework in a Whirlwind

NASA Astrophysics Data System (ADS)

2007-09-01

VLT Image of Supernova in Beautiful Spiral Galaxy NGC 1288 Stars do not like to be alone. Indeed, most stars are members of a binary system, in which two stars circle around each other in an apparently never-ending cosmic ballet. But sometimes, things can go wrong. When the dancing stars are too close to each other, one of them can start devouring its partner. If the vampire star is a white dwarf - a burned-out star that was once like our Sun - this greed can lead to a cosmic catastrophe: the white dwarf explodes as a Type Ia supernova. In July 2006, ESO's Very Large Telescope took images of such a stellar firework in the galaxy NGC 1288. The supernova - designated SN 2006dr - was at its peak brightness, shining as bright as the entire galaxy itself, bearing witness to the amount of energy released. ESO PR Photo 39/07 ESO PR Photo 39/07 SN 2006dr in NGC 1288 NGC 1288 is a rather spectacular spiral galaxy, seen almost face-on and showing multiple spiral arms pirouetting around the centre. Bearing a strong resemblance to the beautiful spiral galaxy NGC 1232, it is located 200 million light-years away from our home Galaxy, the Milky Way. Two main arms emerge from the central regions and then progressively split into other arms when moving further away. A small bar of stars and gas runs across the centre of the galaxy. The first images of NGC 1288, obtained during the commissioning period of the FORS instrument on ESO's VLT in 1998, were of such high quality that they have allowed astronomers [1] to carry out a quantitative analysis of the morphology of the galaxy. They found that NGC 1288 is most probably surrounded by a large dark matter halo. The appearance and number of spiral arms are indeed directly related to the amount of dark matter in the galaxy's halo. The supernova was first spotted by amateur astronomer Berto Monard. On the night of 17 July 2006, Monard used his 30-cm telescope in the suburbs of Pretoria in South Africa and discovered the supernova as an

GUIs in the MIDAS environment

NASA Technical Reports Server (NTRS)

Ballester, P.

1992-01-01

MIDAS (Munich Image Data Analysis System) is the image processing system developed at ESO for astronomical data reduction. MIDAS is used for off-line data reduction at ESO and many astronomical institutes all over Europe. In addition to a set of general commands, enabling to process and analyze images, catalogs, graphics and tables, MIDAS includes specialized packages dedicated to astronomical applications or to specific ESO instruments. Several graphical interfaces are available in the MIDAS environment: XHelp provides an interactive help facility, and XLong and XEchelle enable data reduction of long-slip and echelle spectra. GUI builders facilitate the development of interfaces. All ESO interfaces comply to the ESO User Interfaces Common Conventions which secures an identical look and feel for telescope operations, data analysis, and archives.

The Star, the Dwarf and the Planet

NASA Astrophysics Data System (ADS)

2006-10-01

Astronomers have detected a new faint companion to the star HD 3651, already known to host a planet. This companion, a brown dwarf, is the faintest known companion of an exoplanet host star imaged directly and one of the faintest T dwarfs detected in the Solar neighbourhood so far. The detection yields important information on the conditions under which planets form. "Such a system is an interesting example that might prove that planets and brown dwarfs can form around the same star", said Markus Mugrauer, lead author of the paper presenting the discovery. ESO PR Photo 39a/06 ESO PR Photo 39a/06 The Companion to HD 3651 HD 3651 is a star slightly less massive than the Sun, located 36 light-years away in the constellation Pisces (the "Fish"). For several years, it has been known to harbour a planet less massive than Saturn, sitting closer to its parent star than Mercury is from the Sun: the planet accomplishes a full orbit in 62 days. Mugrauer and his colleagues first spotted the faint companion in 2003 on images from the 3.8-m United Kingdom Infrared Telescope (UKIRT) in Hawaii. Observations in 2004 and 2006 using ESO's 3.6 m New Technology Telescope (NTT) at La Silla provided the crucial confirmation that the speck of light is not a spurious background star, but indeed a true companion. The newly found companion, HD 3651B, is 16 times further away from HD 3651 than Neptune is from the Sun. HD 3651B is the dimmest directly imaged companion of an exoplanet host star. Furthermore, as it is not detected on the photographic plates of the Palomar All Sky Survey, the companion must be even fainter in the visible spectral range than in the infrared, meaning it is a very cool low-mass sub-stellar object. Comparing its characteristics with theoretical models, the astronomers infer that the object has a mass between 20 and 60 Jupiter masses, and a temperature between 500 and 600 degrees Celsius. It is thus ten times colder and 300 000 less luminous than the Sun. These

Gender Systematics in Telescope Time Allocation at ESO

NASA Astrophysics Data System (ADS)

Patat, F.

2016-09-01

The results of a comprehensive statistical analysis of gender systematics in the time allocation process at ESO are presented. The sample on which the study is based includes more than 13 000 Normal and Short proposals, submitted by about 3000 principal investigators (PI) over eight years. The genders of PIs, and of the panel members of the Observing Programmes Committee (OPC), were used, together with their career level, to analyse the grade distributions and the proposal success rates. Proposals submitted by female PIs show a significantly lower probability of being allocated time. The proposal success rates (defined as number of top ranked runs over requested runs) are 16.0 ± 0.6% and 22.0 ± 0.4% for females and males, respectively. To a significant extent the disparity is related to different input distributions in terms of career level. The seniority of male PIs is significantly higher than that of female PIs, with only 34% of the female PIs being professionally employed astronomers (compared to 53% for male PIs). A small, but statistically significant, gender-dependent behaviour is measured for the OPC referees: both genders show the same systematics, but they are larger for males than females. The PI female/male fraction is very close to 30/70; although far from parity, the fraction is higher than that observed, for instance, among IAU membership.

Detection of spectroscopic binaries: lessons from the Gaia-ESO survey

NASA Astrophysics Data System (ADS)

van der Swaelmen, Mathieu; Merle, Thibault; van Eck, Sophie; Jorissen, Alain; Zwitter, Tomaž

2018-04-01

The Gaia-ESO survey (GES; Gilmore et al. (2012), Randich et al. (2013)) is a spectroscopic survey complementing the Gaia mission to bring accurate radial velocities and chemical abundances for 105 stars. Merle et al. (submitted to A&A see also this volume) developped a tool (DOE) to detect multiple peaks in the cross-correlation functions (CCFs) of GES spectra. Using the GIRAFFE HR10 and HR21 settings, we were able to compare the efficiency of our SB detection tool depending on the wavelength range and resolution. We show that a careful design of CCF masks can improve the detection rate in the HR21 settings. HR21 spectra are similar to the ones produced by the RVS spectrograph of the Gaia mission, though the lower resolution of RVS spectra may result in a lower detection efficiency than the case of HR21. Analysis of RVS spectra in the context of spectroscopic binaries can take advantage of the lessons learnt from the GES to maximize the detection rate.

Directives préalables

PubMed Central

O’Sullivan, Rory; Mailo, Kevin; Angeles, Ricardo; Agarwal, Gina

2015-01-01

Résumé Objectif Établir la prévalence de patients dotés de directives préalables dans une pratique familiale et décrire les points de vue des patients quant au rôle du médecin de famille dans l’amorce de discussions à propos des directives préalables. Conception Un questionnaire auquel les patients ont répondu eux-mêmes. Contexte Une clinique d’enseignement en médecine familiale achalandée en milieu urbain, à Hamilton, en Ontario. Participants Un échantillon de commodité formé de patients adultes qui se sont présentés à la clinique durant une semaine de travail typique. Principaux paramètres à l’étude La prévalence des directives préalables dans une population de patients a été déterminée et les attentes à l’endroit du rôle de leur médecin de famille ont été sollicitées. Résultats Les répondants au sondage étaient au nombre de 800 (un taux de réponse de 72,5 %) et leurs groupes d’âges étaient bien répartis; 19,7 % d’entre eux avaient rédigé des directives préalables et 43,8 % avaient déjà discuté du sujet des directives préalables, mais seulement 4,3 % de ces discussions avaient eu lieu avec un médecin de famille. Dans 5,7 % des cas, un médecin de famille avait soulevé la question; 72,3 % des répondants croyaient que les patients devraient amorcer la discussion. Les patients qui considéraient les directives préalables d’une importance extrême étaient considérablement plus enclins à vouloir que leur médecin de famille commence la conversation (rapport de cotes de 3,98; p < ,05). Conclusion Les directives préalables n’étaient pas systématiquement abordées dans la pratique familiale. La plupart des patients préféraient amorcer la discussion des directives préalables. Toutefois, les patients qui considéraient le sujet d’une extrême importance voulaient que leur médecin de famille commence la discussion.

One-Pot Conversion of Epoxidized Soybean Oil (ESO) into Soy-Based Polyurethanes by MoCl₂O₂ Catalysis.

PubMed

Pantone, Vincenzo; Annese, Cosimo; Fusco, Caterina; Fini, Paola; Nacci, Angelo; Russo, Antonella; D'Accolti, Lucia

2017-02-21

An innovative and eco-friendly one-pot synthesis of bio-based polyurethanes is proposed via the epoxy-ring opening of epoxidized soybean oil (ESO) with methanol, followed by the reaction of methoxy bio-polyols intermediates with 2,6-tolyl-diisocyanate (TDI). Both synthetic steps, methanolysis and polyurethane linkage formation, are promoted by a unique catalyst, molybdenum(VI) dichloride dioxide (MoCl₂O₂), which makes this procedure an efficient, cost-effective, and environmentally safer method amenable to industrial scale-up.

Significant Suppression of CT Radiation-Induced DNA Damage in Normal Human Cells by the PrC-210 Radioprotector.

PubMed

Jermusek, Frank; Benedict, Chelsea; Dreischmeier, Emma; Brand, Michael; Uder, Michael; Jeffery, Justin J; Ranallo, Frank N; Fahl, William E

2018-05-21

While computed tomography (CT) is now commonly used and considered to be clinically valuable, significant DNA double-strand breaks (γ-H2AX foci) in white blood cells from adult and pediatric CT patients have been frequently reported. In this study to determine whether γ-H2AX foci and X-ray-induced naked DNA damage are suppressed by administration of the PrC-210 radioprotector, human blood samples were irradiated in a CT scanner at 50-150 mGy with or without PrC-210, and γ-H2AX foci were scored. X-ray-induced naked DNA damage was also studied, and the DNA protective efficacy of PrC-210 was compared against 12 other common "antioxidants." PrC-210 reduced CT radiation-induced γ-H2AX foci in white blood cells to near background ( P < 0.0001) at radiation doses of 50-150 mGy. PrC-210 was most effective among the 13 "antioxidants" in reducing naked DNA X-ray damage, and its addition at 30 s before an • OH pulse reduced to background the • OH insult that otherwise induced >95% DNA damage. A systemic PrC-210 dose known to confer 100% survival in irradiated mice had no discernible effect on micro-CT image signal-to-noise ratio and CT image integrity. PrC-210 suppressed DNA damage to background or near background in each of these assay systems, thus supporting its development as a radioprotector for humans in multiple radiation exposure settings.

The Gaia-ESO Survey: dynamics of ionized and neutral gas in the Lagoon nebula (M 8)

NASA Astrophysics Data System (ADS)

Damiani, F.; Bonito, R.; Prisinzano, L.; Zwitter, T.; Bayo, A.; Kalari, V.; Jiménez-Esteban, F. M.; Costado, M. T.; Jofré, P.; Randich, S.; Flaccomio, E.; Lanzafame, A. C.; Lardo, C.; Morbidelli, L.; Zaggia, S.

2017-08-01

Aims: We present a spectroscopic study of the dynamics of the ionized and neutral gas throughout the Lagoon nebula (M 8), using VLT-FLAMES data from the Gaia-ESO Survey. The new data permit exploration of the physical connections between the nebular gas and the stellar population of the associated star cluster NGC 6530. Methods: We characterized through spectral fitting emission lines of Hα, [N II] and [S II] doublets, [O III], and absorption lines of sodium D doublet, using data from the FLAMES-Giraffe and UVES spectrographs, on more than 1000 sightlines toward the entire face of the Lagoon nebula. Gas temperatures are derived from line-width comparisons, densities from the [S II] doublet ratio, and ionization parameter from Hα/[N II] ratio. Although doubly-peaked emission profiles are rarely found, line asymmetries often imply multiple velocity components along the same line of sight. This is especially true for the sodium absorption, and for the [O III] lines. Results: Spatial maps for density and ionization are derived, and compared to other known properties of the nebula and of its massive stars 9 Sgr, Herschel 36 and HD 165052 which are confirmed to provide most of the ionizing flux. The detailed velocity fields across the nebula show several expanding shells, related to the cluster NGC 6530, the O stars 9 Sgr and Herschel 36, and the massive protostar M 8East-IR. The origins of kinematical expansion and ionization of the NGC 6530 shell appear to be different. We are able to put constrains on the line-of-sight (relative or absolute) distances between some of these objects and the molecular cloud. The data show that the large obscuring band running through the middle of the nebula is being compressed by both sides, which might explain its enhanced density. We also find an unexplained large-scale velocity gradient across the entire nebula. At larger distances, the transition from ionized to neutral gas is studied using the sodium lines. Based on observations

The Gaia-ESO Survey: Structural and dynamical properties of the young cluster Chamaeleon I

NASA Astrophysics Data System (ADS)

Sacco, G. G.; Spina, L.; Randich, S.; Palla, F.; Parker, R. J.; Jeffries, R. D.; Jackson, R.; Meyer, M. R.; Mapelli, M.; Lanzafame, A. C.; Bonito, R.; Damiani, F.; Franciosini, E.; Frasca, A.; Klutsch, A.; Prisinzano, L.; Tognelli, E.; Degl'Innocenti, S.; Prada Moroni, P. G.; Alfaro, E. J.; Micela, G.; Prusti, T.; Barrado, D.; Biazzo, K.; Bouy, H.; Bravi, L.; Lopez-Santiago, J.; Wright, N. J.; Bayo, A.; Gilmore, G.; Bragaglia, A.; Flaccomio, E.; Koposov, S. E.; Pancino, E.; Casey, A. R.; Costado, M. T.; Donati, P.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Magrini, L.; Monaco, L.; Morbidelli, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2017-05-01

Investigating the physical mechanisms driving the dynamical evolution of young star clusters is fundamental to our understanding of the star formation process and the properties of the Galactic field stars. The young ( 2 Myr) and partially embedded cluster Chamaeleon I is one of the closest laboratories for the study of the early stages of star cluster dynamics in a low-density environment. The aim of this work is to study the structural and kinematical properties of this cluster combining parameters from the high-resolution spectroscopic observations of the Gaia-ESO Survey with data from the literature. Our main result is the evidence of a large discrepancy between the velocity dispersion (σstars = 1.14 ± 0.35 km s-1) of the stellar population and the dispersion of the pre-stellar cores ( 0.3 km s-1) derived from submillimeter observations. The origin of this discrepancy, which has been observed in other young star clusters, is not clear. It has been suggested that it may be due to either the effect of the magnetic field on the protostars and the filaments or to the dynamical evolution of stars driven by two-body interactions. Furthermore, the analysis of the kinematic properties of the stellar population puts in evidence a significant velocity shift ( 1 km s-1) between the two subclusters located around the north and south main clouds of the cluster. This result further supports a scenario where clusters form from the evolution of multiple substructures rather than from a monolithic collapse. Using three independent spectroscopic indicators (the gravity indicator γ, the equivalent width of the Li line at 6708 Å, and the Hα 10% width), we performed a new membership selection. We found six new cluster members all located in the outer region of the cluster, proving that Chamaeleon I is probably more extended than previously thought. Starting from the positions and masses of the cluster members, we derived the level of substructure Q, the surface density Σ, and

Revealing the Beast Within

NASA Astrophysics Data System (ADS)

2003-07-01

Deeply Embedded Massive Stellar Clusters Discovered in Milky Way Powerhouse Summary Peering into a giant molecular cloud in the Milky Way galaxy - known as W49 - astronomers from the European Southern Observatory (ESO) have discovered a whole new population of very massive newborn stars . This research is being presented today at the International Astronomical Union's 25th General Assembly held in Sydney, Australia, by ESO-scientist João Alves. With the help of infrared images obtained during a period of excellent observing conditions with the ESO 3.5-m New Technology Telescope (NTT) at the La Silla Observatory (Chile), the astronomers looked deep into this molecular cloud and discovered four massive stellar clusters, with hot and energetic stars as massive as 120 solar masses. The exceedingly strong radiation from the stars in the largest of these clusters is "powering" a 20 light-year diameter region of mostly ionized hydrogen gas (a "giant HII region"). W49 is one of the most energetic regions of star formation in the Milky Way. With the present discovery, the true sources of the enormous energy have now been revealed for the first time, finally bringing to an end some decades of astronomical speculations and hypotheses. PR Photo 21a/03 : Colour Composite of W49A (NTT+SOFI). PR Photo 21b/03 : Radio and Near-Infrared Composite of W49A Giant molecular clouds Stars form predominantly inside Giant Molecular Clouds which populate our Galaxy, the Milky Way. One of the most prominent of these is W49 , which has a mass of a million solar masses. It is located some 37,000 light-years away and is the most luminous star-forming region known in our home galaxy: its luminosity is several million times the luminosity of our Sun. A smaller region within this cloud is denoted W49A - this is one of the strongest radio-emitting areas known in the Galaxy . Massive stars are excessive in all ways. Compared to their smaller and ligther brethren, they form at an Olympic speed and

New Light on Dark Energy

NASA Astrophysics Data System (ADS)

2008-01-01

Using ESO's Very Large Telescope Interferometer, astronomers have probed the inner parts of the disc of material surrounding a young stellar object, witnessing how it gains its mass before becoming an adult. ESO PR Photo 03/08 ESO PR Photo 03a/08 The disc around MWC 147 (Artist's Impression) The astronomers had a close look at the object known as MWC 147, lying about 2,600 light years away towards the constellation of Monoceros ('the Unicorn'). MWC 147 belongs to the family of Herbig Ae/Be objects. These have a few times the mass of our Sun and are still forming, increasing in mass by swallowing material present in a surrounding disc. MWC 147 is less than half a million years old. If one associated the middle-aged, 4.6 billion year old Sun with a person in his early forties, MWC 147 would be a 1-day-old baby [1]. The morphology of the inner environment of these young stars is however a matter of debate and knowledge of it is important to better understand how stars and their cortège of planets form. The astronomers Stefan Kraus, Thomas Preibisch, and Keiichi Ohnaka have used the four 8.2-m Unit Telescopes of ESO's Very Large Telescope to this purpose, combining the light from two or three telescopes with the MIDI and AMBER instruments. "With our VLTI/MIDI and VLTI/AMBER observations of MWC147, we combine, for the first time, near- and mid-infrared interferometric observations of a Herbig Ae/Be star, providing a measurement of the disc size over a wide wavelength range [2]," said Stefan Kraus, lead-author of the paper reporting the results. "Different wavelength regimes trace different temperatures, allowing us to probe the disc's geometry on the smaller scale, but also to constrain how the temperature changes with the distance from the star." The near-infrared observations probe hot material with temperatures of up to a few thousand degrees in the innermost disc regions, while the mid-infrared observations trace cooler dust further out in the disc. The

The Growing-up of a Star

NASA Astrophysics Data System (ADS)

2008-01-01

Using ESO's Very Large Telescope Interferometer, astronomers have probed the inner parts of the disc of material surrounding a young stellar object, witnessing how it gains its mass before becoming an adult. ESO PR Photo 03/08 ESO PR Photo 03a/08 The disc around MWC 147 (Artist's Impression) The astronomers had a close look at the object known as MWC 147, lying about 2,600 light years away towards the constellation of Monoceros ('the Unicorn'). MWC 147 belongs to the family of Herbig Ae/Be objects. These have a few times the mass of our Sun and are still forming, increasing in mass by swallowing material present in a surrounding disc. MWC 147 is less than half a million years old. If one associated the middle-aged, 4.6 billion year old Sun with a person in his early forties, MWC 147 would be a 1-day-old baby [1]. The morphology of the inner environment of these young stars is however a matter of debate and knowledge of it is important to better understand how stars and their cortège of planets form. The astronomers Stefan Kraus, Thomas Preibisch, and Keiichi Ohnaka have used the four 8.2-m Unit Telescopes of ESO's Very Large Telescope to this purpose, combining the light from two or three telescopes with the MIDI and AMBER instruments. "With our VLTI/MIDI and VLTI/AMBER observations of MWC147, we combine, for the first time, near- and mid-infrared interferometric observations of a Herbig Ae/Be star, providing a measurement of the disc size over a wide wavelength range [2]," said Stefan Kraus, lead-author of the paper reporting the results. "Different wavelength regimes trace different temperatures, allowing us to probe the disc's geometry on the smaller scale, but also to constrain how the temperature changes with the distance from the star." The near-infrared observations probe hot material with temperatures of up to a few thousand degrees in the innermost disc regions, while the mid-infrared observations trace cooler dust further out in the disc. The

Characterization of Pr:LuAG scintillating crystals for X-ray spectroscopy

NASA Astrophysics Data System (ADS)

Bertoni, R.; Bonesini, M.; Cervi, T.; Clemenza, M.; De Bari, A.; Falcone, A.; Mazza, R.; Menegolli, A.; Nastasi, M.; Rossella, M.

2016-07-01

The main features of the Pr doped Lu3Al5O12 (Pr:LuAG) scintillating crystals for X-ray spectroscopy applications have been studied using different radioactive sources and photo-detectors. Pr:LuAG is cheaper, compared to a Germanium detector, but with remarkable properties which make it useful for many applications, from fundamental physics measurements to the PET imaging for medical purposes: high density, elevate light yield, fast response, high energy resolution, no hygroscopicity. A sample of Pr:LuAG crystals with 14 mm×14 mm surface area and 13 mm thickness and a NaI crystal of the same surface and 26 mm thickness used as a reference have been characterized with several radioactive sources, emitting photons in the range 100-1000keV. Different light detectors were adopted for the Pr:LuAG studies, sensitive to its UV emission (peak at 310 nm): a 3 in. PMT (Hamamatsu R11065) and new arrays of Hamamatsu SiPM S13361, with siliconic resin as a window. Preliminary results are presented on the performance of the Pr:LuAG crystals, to be mounted in a 2 × 2 array to be tested in the 2015 run of the FAMU experiment at RIKEN-RAL muon facility. The goal is the detection of the X-rays (around 130 keV) emitted during the de-excitation processes of the muonic hydrogen after the excitation with an IR laser with wavelength set at the resonance of the hyperfine splitting, to measure the muonic atom proton radius with unprecedented precision.

Infectivity-associated PrPSc and disease duration-associated PrPSc of mouse BSE prions

PubMed Central

Miyazawa, Kohtaro; Okada, Hiroyuki; Masujin, Kentaro; Iwamaru, Yoshifumi; Yokoyama, Takashi

2015-01-01

ABSTRACT Disease-related prion protein (PrPSc), which is a structural isoform of the host-encoded cellular prion protein, is thought to be a causative agent of transmissible spongiform encephalopathies. However, the specific role of PrPSc in prion pathogenesis and its relationship to infectivity remain controversial. A time-course study of prion-affected mice was conducted, which showed that the prion infectivity was not simply proportional to the amount of PrPSc in the brain. Centrifugation (20,000 ×g) of the brain homogenate showed that most of the PrPSc was precipitated into the pellet, and the supernatant contained only a slight amount of PrPSc. Interestingly, mice inoculated with the obtained supernatant showed incubation periods that were approximately 15 d longer than those of mice inoculated with the crude homogenate even though both inocula contained almost the same infectivity. Our results suggest that a small population of fine PrPSc may be responsible for prion infectivity and that large, aggregated PrPSc may contribute to determining prion disease duration. PMID:26555211

Cost utility of telaprevir-PR (peginterferon-ribavirin) versus boceprevir-PR and versus PR alone in chronic hepatitis C in The Netherlands.

PubMed

Vellopoulou, Aikaterini; van Agthoven, Michel; van der Kolk, Annemarie; de Knegt, Robert J; Berdeaux, Gilles; Cure, Sandrine; Bianic, Florence; Lamotte, Mark

2014-12-01

The hepatitis C virus may lead to cirrhosis, liver cancer, liver transplant, and increased mortality. With standard treatment peginterferon-alpha and ribavirin (PR), sustained viral response (SVR) was less than 50 %. SVR rates improve greatly when PR is combined with telaprevir or boceprevir. The aim of this study was to assess the cost utility of telaprevir-peginterferon-ribavirin (TPR) versus PR and boceprevir-peginterferon-ribavirin (BPR) in treatment-naïve (TN) and treatment-experienced (TE) adults with chronic hepatitis C in the Netherlands. A Markov model with a lifelong time horizon and annual cycles was developed. Clinical data stemmed from phase III trials (TPR vs PR, BPR vs PR). A mixed treatment comparison (MTC) was developed to compare TPR and BPR indirectly. Unit costs and utilities based on EQ-5D were established in a Dutch cross-sectional study. Cost per quality-adjusted life-years (QALYs) was calculated according to the societal perspective. Treating TN patients with TPR generates 1.12 additional QALYs with €333 additional cost compared with PR, resulting in an incremental cost-utility ratio of €299/QALY. In TE patients, TPR dominates PR with cost savings (-€7,819) and 1.63 additional QALYs. TPR dominates BPR yielding additional QALYs (0.26 in TN; 0.71 in TE) and cost savings (-€7,296, -€18,144, respectively). TPR seems a cost-effective alternative to PR in TN patients and dominant in TE patients. TPR was a dominant, more effective and less costly alternative to BPR in both patient types. The cost effectiveness of both TPR and BPR is well below generally accepted willingness-to-pay thresholds and may be considered cost effective.

The Milky Way above La Silla

NASA Astrophysics Data System (ADS)

2004-09-01

Anybody who visits a high-altitude astronomical observatory at this time of the year will be impressed by the beauty of the Milky Way band that stretches across the sky. Compared to the poor views from cities and other human conglomerations, the dark and bright nebulae come into view together with an astonishing palette of clear stellar colours. This view above the ESO La Silla Observatory in the southernmost part of the Atacama desert was obtained some evenings ago by ESO Software Engineer Nico Housen. Normally stationed at the Paranal Observatory, he seized the opportunity of a visit to ESO's other observatory site to produce this amazing vista of the early evening scenery. To the left is the decommisioned 15-metre dish of the Swedish-ESO Submillimetre Telescope (SEST), and on the right in the background is the dome of the ESO 3.6-metre telescope, at the highest point of the mountain. The southern Milky Way is seen along the right border of the SEST and above the 3.6 metre telescope. There is an upside-down reflection of the sky and the horizon behind the photographer in the highly polished antenna dish of the SEST. Besides the reflection of the horizon (the darker part in the top of the dish) and the Milky Way (which runs as a thin cloud from the bottom of the dish up to the horizon) there is also a yellow area of light to the right. This is the reflection of the city lights of the city of La Serena, about 100 km away and too faint to disturb observations of celestial objects high above La Silla. The 3.6-m telescope began operations in 1976 and was ESO's largest telescope until the advent of the VLT at Paranal. Never endowed with a fancy name like the VLT Unit telescopes, the "3.6-m" houses several state-of-the-art astronomical instruments, including the ultra-precise HARPS facility that is used to hunt for exoplanets, cf. ESO PR 22/04. The SEST was for a long time the only instrument of its kind in the southern hemisphere. With it, ESO gained invaluable

ASASSN-18gq: Discovery of A Low-Luminosity Transient Towards Very Nearby ( 3.4 Mpc) Galaxy ESO 325- G?011

NASA Astrophysics Data System (ADS)

Nicholls, B.; Brimacombe, J.; Vallely, P.; Dong, Subo; Stanek, K. Z.; Kochanek, C. S.; Brown, J. S.; Shields, J.; Thompson, T. A.; Shappee, B. J.; Holoien, T. W.-S.; Prieto, J. L.; Bersier, D.; Bose, S.; Chen, Ping; Stritzinger, M.; Holmbo, S.

2018-04-01

During the ongoing All Sky Automated Survey for SuperNovae (ASAS-SN, Shappee et al. 2014), using data from the quadruple 14-cm "Payne-Gaposchkin" telescope in Sutherland, South Africa, and the quadruple 14-cm "Cassius" and "Paczynski" telescopes in Cerro Tololo, Chile, we discovered a new transient source, most likely a supernova, in the low surface brightness galaxy ESO 325- G?011.

Anatomy of a Bird

NASA Astrophysics Data System (ADS)

2007-12-01

Using ESO's Very Large Telescope, an international team of astronomers [1] has discovered a stunning rare case of a triple merger of galaxies. This system, which astronomers have dubbed 'The Bird' - albeit it also bears resemblance with a cosmic Tinker Bell - is composed of two massive spiral galaxies and a third irregular galaxy. ESO PR Photo 55a/07 ESO PR Photo 55a/07 The Tinker Bell Triplet The galaxy ESO 593-IG 008, or IRAS 19115-2124, was previously merely known as an interacting pair of galaxies at a distance of 650 million light-years. But surprises were revealed by observations made with the NACO instrument attached to ESO's VLT, which peered through the all-pervasive dust clouds, using adaptive optics to resolve the finest details [2]. Underneath the chaotic appearance of the optical Hubble images - retrieved from the Hubble Space Telescope archive - the NACO images show two unmistakable galaxies, one a barred spiral while the other is more irregular. The surprise lay in the clear identification of a third, clearly separate component, an irregular, yet fairly massive galaxy that seems to be forming stars at a frantic rate. "Examples of mergers of three galaxies of roughly similar sizes are rare," says Petri Väisänen, lead author of the paper reporting the results. "Only the near-infrared VLT observations made it possible to identify the triple merger nature of the system in this case." Because of the resemblance of the system to a bird, the object was dubbed as such, with the 'head' being the third component, and the 'heart' and 'body' making the two major galaxy nuclei in-between of tidal tails, the 'wings'. The latter extend more than 100,000 light-years, or the size of our own Milky Way. ESO PR Photo 55b/07 ESO PR Photo 55b/07 Anatomy of a Bird Subsequent optical spectroscopy with the new Southern African Large Telescope, and archive mid-infrared data from the NASA Spitzer space observatory, confirmed the separate nature of the 'head', but also added

Active imaging with the aids of polarization retrieve in turbid media system

NASA Astrophysics Data System (ADS)

Tao, Qiangqiang; Sun, Yongxuan; Shen, Fei; Xu, Qiang; Gao, Jun; Guo, Zhongyi

2016-01-01

We propose a novel active imaging based on the polarization retrieve (PR) method in turbid media system. In our simulations, the Monte Carlo (MC) algorithm has been used to investigate the scattering process between the incident photons and the scattering particles, and the visually concordant object but with different polarization characteristics in different regions, has been selected as the original target that is placed in the turbid media. Under linearly and circularly polarized illuminations, the simulation results demonstrate that the corresponding polarization properties can provide additional information for the imaging, and the contrast of the polarization image can also be enhanced greatly compared to the simplex intensity image in the turbid media. Besides, the polarization image adjusted by the PR method can further enhance the visibility and contrast. In addition, by PR imaging method, with the increasing particles' size in Mie's scale, the visibility can be enhanced, because of the increased forward scattering effect. In general, in the same circumstance, the circular polarization images can offer a better contrast and visibility than that of linear ones. The results indicate that the PR imaging method is more applicable to the scattering media system with relatively larger particles such as aerosols, heavy fog, cumulus, and seawater, as well as to biological tissues and blood media.

Gaia-ESO Survey: Global properties of clusters Trumpler 14 and 16 in the Carina nebula ⋆⋆

NASA Astrophysics Data System (ADS)

Damiani, F.; Klutsch, A.; Jeffries, R. D.; Randich, S.; Prisinzano, L.; Maíz Apellániz, J.; Micela, G.; Kalari, V.; Frasca, A.; Zwitter, T.; Bonito, R.; Gilmore, G.; Flaccomio, E.; Francois, P.; Koposov, S.; Lanzafame, A. C.; Sacco, G. G.; Bayo, A.; Carraro, G.; Casey, A. R.; Alfaro, E. J.; Costado, M. T.; Donati, P.; Franciosini, E.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Magrini, L.; Monaco, L.; Morbidelli, L.; Worley, C. C.; Vink, J. S.; Zaggia, S.

2017-07-01

Aims: We present the first extensive spectroscopic study of the global population in star clusters Trumpler 16, Trumpler 14, and Collinder 232 in the Carina nebula, using data from the Gaia-ESO Survey, down to solar-mass stars. Methods: In addition to the standard homogeneous survey data reduction, a special processing was applied here because of the bright nebulosity surrounding Carina stars. Results: We find about 400 good candidate members ranging from OB types down to slightly subsolar masses. About 100 heavily reddened early-type Carina members found here were previously unrecognized or poorly classified, including two candidate O stars and several candidate Herbig Ae/Be stars. Their large brightness makes them useful tracers of the obscured Carina population. The spectroscopically derived temperatures for nearly 300 low-mass members enables the inference of individual extinction values and the study of the relative placement of stars along the line of sight. Conclusions: We find a complex spatial structure with definite clustering of low-mass members around the most massive stars and spatially variable extinction. By combining the new data with existing X-ray data, we obtain a more complete picture of the three-dimensional spatial structure of the Carina clusters and of their connection to bright and dark nebulosity and UV sources. The identification of tens of background giants also enables us to determine the total optical depth of the Carina nebula along many sightlines. We are also able to put constraints on the star formation history of the region with Trumpler 14 stars found to be systematically younger than stars in other subclusters. We find a large percentage of fast-rotating stars among Carina solar-mass members, which provide new constraints on the rotational evolution of pre-main-sequence stars in this mass range. Based on observations collected with the FLAMES spectrograph at VLT/UT2 telescope (Paranal Observatory, ESO, Chile), for the Gaia-ESO

Isolated Star-Forming Cloud Discovered in Intracluster Space

NASA Astrophysics Data System (ADS)

2003-01-01

galaxies, Messier 86 and Messier 84, indicate the presence of other isolated HII regions, thus suggesting that isolated star formation may occur more generally in galaxies. If so, this process may provide a natural explanation to the current riddle why some young stars are found high up in the halo of our own Milky Way galaxy, far from the star-forming clouds in the main plane. The Virgo Cluster ESO PR Photo 04a/03 ESO PR Photo 04a/03 [Preview - JPEG: 400 x 428 pix - 74k [Normal - JPEG: 800 x 855 pix - 408k] [Hi-Res - JPEG: 4252 x 4544 pix - 10.3M] ESO PR Photo 04b/03 ESO PR Photo 04b/03 [Preview - JPEG: 433 x 400 pix - 60k [Normal - JPEG: 865 x 800 pix - 456k] [Hi-Res - JPEG: 3077 x 2847 pix - 4.2M] Captions: PR Photo 04a/03 displays a sky field near some of the brighter galaxies in the Virgo Cluster. It was obtained in April 2000 with the Wide Field Imager (WFI) at the La Silla Observatory (exposure 6 x 5 min; red R-band; seeing 1.3 arcsec). The large elliptical galaxy at the centre is Messier 84; the elongated image of NGC 4388 (an active spiral galaxy, seen from the side) is in the lower left corner. The field measures 16.9 x 15.7 arcmin2. PR Photo 04b/03 shows a larger region of the Virgo cluster, with the galaxies Messier 86 (at the upper edge of the field, to the left of the centre), as well as Messier 84 (upper right) and NGC 4388 (just below the centre) that are also seen in PR Photo 04a/03. It is reproduced from a long-exposure Subaru Suprime-Cam image, obtained in the red light of ionized hydrogen (the H-alpha spectral line at wavelength 656.2 nm). In order to show the faintest possible hydrogen emitting objects embedded in the outskirts of bright galaxies, their smooth envelopes have been "subtracted" during the image processing. The field measures 34 x 27 arcmin2. Part of this sky field is shown in colour in PR Photo 04c/03. Captions: PR Photo 04a/03 displays a sky field near some of the brighter galaxies in the Virgo Cluster. It was obtained in April 2000

Spectroscopic study of the elusive globular cluster ESO452-SC11 and its surroundings

NASA Astrophysics Data System (ADS)

Koch, Andreas; Hansen, Camilla Juul; Kunder, Andrea

2017-08-01

Globular clusters (GCs) have long been recognized as being amongst the oldest objects in the Galaxy. As such, they have the potential of playing a pivotal role in deciphering the Milky Way's early history. Here we present the first spectroscopic study of the low-mass system ESO452-SC11 using the AAOmega multifibre spectrograph at medium resolution. Given the stellar sparsity of this object and the high degree of foreground contamination due to its location toward the Galactic bulge, very few details are known for this cluster - there is no consensus, for instance, about its age, metallicity, or its association with the disk or bulge. We identify five member candidates based on common radial velocity, calcium-triplet metallicity, and position within the GC. Using spectral synthesis, the measurement of accurate Fe-abundances from Fe-lines, and abundances of several α-, Fe-peak, and neutron-capture elements (Si, Ca, Ti,Cr, Co, Ni, Sr, and Eu) is carried out, albeit with large uncertainties. We find that two of the five cluster candidates are likely non-members, as they have deviating iron abundances and [α/Fe] ratios. The cluster mean heliocentric velocity is 19 ± 2 km s-1 with a velocity dispersion of 2.8 ± 3.4 km s-1, a low value in line with its sparse nature and low mass. The mean Fe-abundance from spectral fitting is -0.88 ± 0.03 dex, where the spread is driven by observational errors. Furthermore, the α-elements of the GC candidates are marginally lower than expected for the bulge at similar metallicities. As spectra of hundreds of stars were collected in a 2-degree field centered on ESO452-SC11, a detailed abundance study of the surrounding field was also enabled. The majority of the non-members have slightly higher [α/Fe] ratios, in line with the typical nearby bulge population. A subset of the spectra with measured Fe-peak abundance ratios shows a large scatter around solar values, albeit with large uncertainties. Furthermore, our study provides the

The Orion Nebula: The Jewel in the Sword

NASA Astrophysics Data System (ADS)

2001-01-01

Orion the Hunter is perhaps the best known constellation in the sky, well placed in the evening at this time of the year for observers in both the northern and southern hemispheres, and instantly recognisable. And for astronomers, Orion is surely one of the most important constellations, as it contains one of the nearest and most active stellar nurseries in the Milky Way, the galaxy in which we live. Here tens of thousands of new stars have formed within the past ten million years or so - a very short span of time in astronomical terms. For comparison: our own Sun is now 4,600 million years old and has not yet reached half-age. Reduced to a human time-scale, star formation in Orion would have been going on for just one month as compared to the Sun's 40 years. Just below Orion's belt, the hilt of his sword holds a great jewel in the sky, the beautiful Orion Nebula . Bright enough to be seen with the naked eye, a small telescope or even binoculars show the nebula to be a few tens of light-years' wide complex of gas and dust, illuminated by several massive and hot stars at its core, the famous Trapezium stars . However, the heart of this nebula also conceals a secret from the casual observer. There are in fact about one thousand very young stars about one million years old within the so-called Trapezium Cluster , crowded into a space less than the distance between the Sun and its nearest neighbour stars. The cluster is very hard to observe in visible light, but is clearly seen in the above spectacular image of this area ( ESO PR 03a/01 ), obtained in December 1999 by Mark McCaughrean (Astrophysical Institute Potsdam, Germany) and his collaborators [1] with the infrared multi-mode ISAAC instrument on the ESO Very Large Telescope (VLT) at Paranal (Chile). Many details are seen in the new ISAAC image ESO PR Photo 03b/01 ESO PR Photo 03b/01 [Preview - JPEG: 400 x 589 pix - 62k] [Normal - JPEG: 800 x 1178 pix - 648k] [Hires - JPEG: 1957 x 2881 pix - 2.7M] ESO PR Photo 03c

Final binary star results from the ESO VLT Lunar occultations program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richichi, A.; Fors, O.; Cusano, F.

2014-03-01

We report on 13 subarcsecond binaries, detected by means of lunar occultations in the near-infrared at the ESO Very Large Telescope (VLT). They are all first-time detections except for the visual binary HD 158122, which we resolved for the first time in the near-infrared. The primaries have magnitudes in the range K = 4.5-10.0, and companions in the range K = 6.8-11.1. The magnitude differences have a median value of 2.4, with the largest being 4.6. The projected separations are in the range of 4-168 mas, with a median of 13 mas. We discuss and compare our results with themore » available literature. With this paper, we conclude the mining for binary star detections in the 1226 occultations recorded at the VLT with the ISAAC instrument. We expect that the majority of these binaries may be unresolvable by adaptive optics on current telescopes, and they might be challenging for long-baseline interferometry. However, they constitute an interesting sample for future larger telescopes and for astrometric missions such as GAIA.« less

RFA-based 589-nm guide star lasers for ESO VLT: a paradigm shift in performance, operational simplicity, reliability, and maintenance

NASA Astrophysics Data System (ADS)

Friedenauer, Axel; Karpov, Vladimir; Wei, Daoping; Hager, Manfred; Ernstberger, Bernhard; Clements, Wallace R. L.; Kaenders, Wilhelm G.

2012-07-01

Large telescopes equipped with adaptive optics require 20-25W CW 589-nm sources with emission linewidths of ~5 MHz. These Guide Star (GS) lasers should also be highly reliable and simple to operate and maintain for many years at the top of a mountain facility. Under contract from ESO, industrial partners TOPTICA and MPBC are nearing completion of the development of GS lasers for the ESO VLT, with delivery of the first of four units scheduled for December 2012. We report on the design and performance of the fully-engineered Pre-Production Unit (PPU), including system reliability/availability analysis, the successfully-concluded qualification testing, long-term component and system level tests and long-term maintenance and support planning. The chosen approach is based on ESO's patented narrow-band Raman Fiber Amplifier (EFRA) technology. A master oscillator signal from a linearly-polarized TOPTICA 20-mW, 1178-nm CW diode laser, with stabilized emission frequency and controllable linewidth up to a few MHz, is amplified in an MPBC polarization-maintaining (PM) RFA pumped by a high-power 1120-nm PM fiber laser. With efficient stimulated Brillouin scattering suppression, an unprecedented 40W of narrow-band RFA output has been obtained. This is then mode-matched into a resonant-cavity doubler with a free-spectral-range matching the sodium D2a to D2b separation, allowing simultaneous generation of an additional frequency component (D2b line) to re-pump the sodium atom electronic population. With this technique, the return flux can be increased without having to resort to electro-optical modulators and without the risk of introducing optical wave front distortions. The demonstrated output powers with doubling efficiencies >80% at 589 nm easily exceed the 20W design goal and require less than 700 W of electrical power. In summary, the fiber-based guide star lasers provide excellent beam quality and are modular, turn-key, maintenance-free, reliable, efficient, and ruggedized

A Milestone for the VLT Interferometer

NASA Astrophysics Data System (ADS)

2000-10-01

Less than one month after "First Light" for the fourth 8.2-m YEPUN telescope ( ESO PR 18/00 ), another special moment occurred at ESO's Paranal Observatory. This time, it was the first truly "underground" event, in the 168-metre long Interferometric Tunnel that has been dug beneath the platform at the top of the mountain. As one staff member remarked on this occasion, it was something like "the first scheduled trip of the Paranal metro"! With the successful integration of the first Delay Line on Monday, September 25th, 2000, ESO has accomplished another important step towards the VLT Interferometer (VLTI). It will be followed by the integration of the second Delay Line by the end of November and the third is scheduled for February 2001; both are now in their final development phase in Europe. "VLTI First Light" is then expected to take place soon thereafter, by means of two small special telescopes ("siderostats"). The combination of the light beams from two of the 8.2-m Unit Telescopes will happen in mid-2001. The VLTI Delay Lines The VLTI Delay Lines form essential parts of this very complicated optical system. They serve to ensure that the light beams from several telescopes arrive in phase at the common interferometric focus. Details about how they function may be found in ESO PR 04/98. In order to achieve the necessary performance, ESO has worked with two Dutch contractors, Fokker Space and TNO-TPD - Netherlands Organization for Applied Scientific Research - Institute of Applied Physics , to arrive at a totally new Delay Line concept. Another Dutch participant in the VLTI project is the Nova-ESO VLTI Expertise Centre (NEVEC) , cf. ESO PR 14/00. The installation at Paranal The last twelve months have been very busy for the integration team, with much preparatory work at the VLTI buildings for the final installation of the Delay Line systems. The assembly of the translation mechanisms for the first two Delay Lines in the tunnel started in mid-2000. This included

The Most Remote Gamma-Ray Burst

NASA Astrophysics Data System (ADS)

2000-10-01

seconds is larger than that of the Sun during its entire life time (about 10,000 million years). "Gamma-ray bursts" are in fact by far the most powerful events since the Big Bang that are known in the Universe. While there are indications that gamma-ray bursts originate in star-forming regions within distant galaxies, the nature of such explosions remains a puzzle. Recent observations with large telescopes, e.g. the measurement of the degree of polarization of light from a gamma-ray burst in May 1999 with the VLT ( ESO PR 08/99), are now beginning to cast some light on this long-standing mystery. The afterglow of GRB 000131 ESO PR Photo 28a/00 ESO PR Photo 28a/00 [Preview - JPEG: 400 x 475 pix - 41k] [Normal - JPEG: 800 x 949 pix - 232k] [Full-Res - JPEG: 1200 x 1424 pix - 1.2Mb] ESO PR Photo 28b/00 ESO PR Photo 28b/00 [Preview - JPEG: 400 x 480 pix - 67k] [Normal - JPEG: 800 x 959 pix - 288k] [Full-Res - JPEG: 1200 x 1439 pix - 856k] Caption : PR Photo 28a/00 is a colour composite image of the sky field around the position of the gamma-ray burst GRB 000131 that was detected on January 31, 2000. It is based on images obtained with the ESO Very Large Telescope at Paranal. The object is indicated with an arrow, near a rather bright star (magnitude 9, i.e., over 1 million times brighter than the faintest objects visible on this photo). This and other bright objects in the field are responsible for various unavoidable imaging effects, caused by optical reflections (ring-shaped "ghost images", e.g. to the left of the brightest star) and detector saturation effects (horizontal and vertical straight lines and coloured "coronae" at the bright objects, and areas of "bleeding", e.g. below the bright star). PR Photo 28b/00 shows the rapid fading of the optical counterpart of GRB 000131 (slightly left of the centre), by means of exposures with the VLT on February 4 (upper left), 6 (upper right), 8 (lower left) and March 5 (lower right). It is no longer visible on the last photo

Optimizing content for pre-exposure prophylaxis (PrEP) counseling for men who have sex with men: Perspectives of PrEP users and high-risk PrEP naïve men.

PubMed

Wade Taylor, S; Mayer, Kenneth H; Elsesser, Steven M; Mimiaga, Matthew J; O'Cleirigh, Conall; Safren, Steven A

2014-05-01

Existing trials of antiretroviral (ARV) medication as chemoprophylaxis against HIV reveal that the degree of protection is primarily dependent on product adherence. However, there is a lack of data on targets for behavioral interventions to improve adherence to ARV as prevention. Information from individuals who have used ARV as pre-exposure prophylaxis (PrEP) can inform behavioral intervention development. Thirty-nine HIV-uninfected MSM at high risk for HIV acquisition participated in one of four semi-structured focus groups. Two of the focus groups consisted of MSM who had been prescribed and used PrEP in the context of a clinical trial; the other two consisted of high-risk MSM who had not previously used PrEP. An in-depth, within-case/across-case content analysis resulted in six descriptive themes potentially salient for a PrEP adherence behavioral intervention: (1) motivations to use PrEP, (2) barriers to PrEP use, (3) facilitators to PrEP use, (4) sexual decision-making in the context of PrEP, (5) prospective PrEP education content, and, (6) perceived effective characteristics of PrEP delivery personnel. Addressing these themes in behavioral interventions in the context of prescribing PrEP may result in the optimal "packaging" public health programs that implement PrEP for high-risk MSM.

A 12 μm ISOCAM survey of the ESO-Sculptor field. Data reduction and analysis

NASA Astrophysics Data System (ADS)

Seymour, N.; Rocca-Volmerange, B.; de Lapparent, V.

2007-12-01

We present a detailed reduction of a mid-infrared 12 μm (LW10 filter) ISOCAM open time observation performed on the ESO-Sculptor Survey field (Arnouts et al. 1997, A&AS, 124, 163). A complete catalogue of 142 sources (120 galaxies and 22 stars), detected with high significance (equivalent to 5σ), is presented above an integrated flux density of 0.24 {mJy}. Star/galaxy separation is performed by a detailed study of colour-colour diagrams. The catalogue is complete to 1 {mJy} and, below this flux density, the incompleteness is corrected using two independent methods. The first method uses stars and the second uses optical counterparts of the ISOCAM galaxies; these methods yield consistent results. We also apply an empirical flux density calibration using stars in the field. For each star, the 12 μm flux density is derived by fitting optical colours from a multi-band χ2 to stellar templates (BaSel-2.0) and using empirical optical-IR colour-colour relations. This article is a companion analysis to our 2007 paper (Rocca-Volmerange et al. 2007, A&A, 475, 801) where the 12 μ m faint galaxy counts are presented and analysed per galaxy type with the evolutionary code PÉGASE.3. Based on observations collected at the European Southern Observatory (ESO), La Silla, Chile, and on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, the Netherlands, and the United Kingdom) and with the participation of ISAS and NASA. Full Table [see full textsee full textsee full textsee full textsee full textsee full text] is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/475/791

The Gaia-ESO Survey: Sodium and aluminium abundances in giants and dwarfs. Implications for stellar and Galactic chemical evolution

NASA Astrophysics Data System (ADS)

Smiljanic, R.; Romano, D.; Bragaglia, A.; Donati, P.; Magrini, L.; Friel, E.; Jacobson, H.; Randich, S.; Ventura, P.; Lind, K.; Bergemann, M.; Nordlander, T.; Morel, T.; Pancino, E.; Tautvaišienė, G.; Adibekyan, V.; Tosi, M.; Vallenari, A.; Gilmore, G.; Bensby, T.; François, P.; Koposov, S.; Lanzafame, A. C.; Recio-Blanco, A.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Franciosini, E.; Heiter, U.; Hill, V.; Hourihane, A.; Jofré, P.; Lardo, C.; de Laverny, P.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sbordone, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2016-05-01

Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than ~1.5-2.0 M⊙. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stellar yields lead to very different predictions for the behavior of [Na/Fe] and [Al/Fe] versus [Fe/H]. Overall, the observed trends of these abundances with metallicity are not well reproduced. Aims: We readdress both issues, using new Na and Al abundances determined within the Gaia-ESO Survey. Our aim is to obtain better observational constraints on the behavior of these elements using two samples: I) more than 600 dwarfs of the solar neighborhood and of open clusters and II) low- and intermediate-mass clump giants in six open clusters. Methods: Abundances were determined using high-resolution UVES spectra. The individual Na abundances were corrected for nonlocal thermodynamic equilibrium effects. For the Al abundances, the order of magnitude of the corrections was estimated for a few representative cases. For giants, the abundance trends with stellar mass are compared to stellar evolution models. For dwarfs, the abundance trends with metallicity and age are compared to detailed chemical evolution models. Results: Abundances of Na in stars with mass below ~2.0 M⊙, and of Al in stars below ~3.0 M⊙, seem to be unaffected by internal mixing processes. For more massive stars, the Na overabundance increases with stellar mass. This trend agrees well with predictions of stellar evolutionary models. For Al, our only cluster with giants more massive than 3.0 M⊙, NGC 6705, is Al enriched. However, this might be related to the environment where the cluster was formed. Chemical evolution models that well fit the observed [Na/Fe] vs. [Fe/H] trend in solar neighborhood dwarfs

Faintest Methane Brown Dwarf Discovered with the NTT and VLT

NASA Astrophysics Data System (ADS)

1999-08-01

FORS1 and ISAAC instruments at the VLT 8.2-m ANTU telescope during the first period of VLT observations. Such distant objects are quite red (due to their high redshift) and are best detected by a combination of visible and infrared exposures. Discovery of an extremely infrared object ESO PR Photo 35a/99 ESO PR Photo 35a/99 [Preview - JPEG: 400 x 251 pix - 72k] [Normal - JPEG: 800 x 502 pix - 224k] [High-Res - JPEG: 3000 x 1881 pix - 1.7M] Caption to ESO PR Photo 35a/99 : Part of the NTT Deep Field , with the new Methane Brown Dwarf NTTDF J1205-0744 at the centre. The field measures 1.3 x 1.3 arcmin 2. The object is well visible in the SOFI infrared exposure (left) in the J-band at wavelength 1.25 µm, but not in the SUSI one at a shorter wavelength (right) in the i-band at 0.8 µm. North is up and East is left. The astronomers noted a star-like object of extreme colour in this field. While it was well visible and similarly bright in both SOFI infrared images (J = 20.2 and K = 20.3), it could not be seen at all on the SUSI images in the visible spectral region, even at the longest wavelength (i-band) observed with that instrument (i-J > 6 mag), cf. PR Photo 35a/99 . No "normal" object is known to have such extreme colours. The new object now received the designation NTTDF J1205-0744 , indicating that it was discovered in the NTT Deep Field at the given position on the sky. It seemed that there were only two possibilities. Either it was an extremely distant quasar (redshift about 8) at the edge of the observable universe, or it must be a very cold object in the Milky Way Galaxy. Whatever its nature, this was obviously a most interesting object. Spectroscopic observations of NTTDF J1205-0744 ESO PR Photo 35b/99 ESO PR Photo 35b/99 [Preview - JPEG: 400 x 337 pix - 56k] [Normal - JPEG: 800 x 674 pix - 124k] Caption to ESO PR Photo 35b/99 : The infrared spectrum of NTTDF J1205-0744 , as obtained with SOFI at the NTT and ISAAC at VLT ANTU, and compared to the spectrum of the

A Cosmic Baby-Boom

NASA Astrophysics Data System (ADS)

2005-09-01

Large Population of Galaxies Found in the Young Universe with ESO's VLT The Universe was a more fertile place soon after it was formed than has previously been suspected. A team of French and Italian astronomers [1] made indeed the surprising discovery of a large and unknown population of distant galaxies observed when the Universe was only 10 to 30% its present age. ESO PR Photo 29a/05 ESO PR Photo 29a/05 New Population of Distant Galaxies [Preview - JPEG: 400 x 424 pix - 191k] [Normal - JPEG: 800 x 847 pix - 449k] [HiRes - JPEG: 2269 x 2402 pix - 2.0M] ESO PR Photo 29b/05 ESO PR Photo 29b/05 Average Spectra of Distant Galaxies [Preview - JPEG: 400 x 506 pix - 141k] [Normal - JPEG: 800 x 1012 pix - 320k] This breakthrough is based on observations made with the Visible Multi-Object Spectrograph (VIMOS) as part of the VIMOS VLT Deep Survey (VVDS). The VVDS started early 2002 on Melipal, one of the 8.2-m telescopes of ESO's Very Large Telescope Array [2]. In a total sample of about 8,000 galaxies selected only on the basis of their observed brightness in red light, almost 1,000 bright and vigorously star forming galaxies were discovered that were formed between 9 and 12 billion years ago (i.e. about 1,500 to 4,500 million years after the Big Bang). "To our surprise, says Olivier Le Fèvre, from the Laboratoire d'Astrophysique de Marseille (France) and co-leader of the VVDS project, "this is two to six times higher than had been found previously. These galaxies had been missed because previous surveys had selected objects in a much more restrictive manner than we did. And they did so to accommodate the much lower efficiency of the previous generation of instruments." While observations and models have consistently indicated that the Universe had not yet formed many stars in the first billion years of cosmic time, the discovery announced today by scientists calls for a significant change in this picture. The astronomers indeed find that stars formed two to three times

The Orion Nebula: Still Full of Surprises

NASA Astrophysics Data System (ADS)

2011-01-01

This ethereal-looking image of the Orion Nebula was captured using the Wide Field Imager on the MPG/ESO 2.2-metre telescope at the La Silla Observatory, Chile. This nebula is much more than just a pretty face, offering astronomers a close-up view of a massive star-forming region to help advance our understanding of stellar birth and evolution. The data used for this image were selected by Igor Chekalin (Russia), who participated in ESO's Hidden Treasures 2010 astrophotography competition. Igor's composition of the Orion Nebula was the seventh highest ranked entry in the competition, although another of Igor's images was the eventual overall winner. The Orion Nebula, also known as Messier 42, is one of the most easily recognisable and best-studied celestial objects. It is a huge complex of gas and dust where massive stars are forming and is the closest such region to the Earth. The glowing gas is so bright that it can be seen with the unaided eye and is a fascinating sight through a telescope. Despite its familiarity and closeness there is still much to learn about this stellar nursery. It was only in 2007, for instance, that the nebula was shown to be closer to us than previously thought: 1350 light-years, rather than about 1500 light-years. Astronomers have used the Wide Field Imager on the MPG/ESO 2.2-metre telescope at ESO's La Silla Observatory in Chile to observe the stars within Messier 42. They found that the faint red dwarfs in the star cluster associated with the glowing gas radiate much more light than had previously been thought, giving us further insights into this famous object and the stars that it hosts. The data collected for this science project, with no original intention to make a colour image, have now been reused to create the richly detailed picture of Messier 42 shown here. The image is a composite of several exposures taken through a total of five different filters. Light that passed through a red filter as well as light from a filter that

Enthalpies of formation of Cd–Pr intermetallic compounds and thermodynamic assessment of the Cd–Pr system

PubMed Central

Reichmann, Thomas L.; Richter, Klaus W.; Delsante, Simona; Borzone, Gabriella; Ipser, Herbert

2014-01-01

In the present study standard enthalpies of formation were measured by reaction and solution calorimetry at stoichiometric compositions of Cd2Pr, Cd3Pr, Cd58Pr13 and Cd6Pr. The corresponding values were determined to be −46.0, −38.8, −35.2 and −24.7 kJ/mol(at), respectively. These data together with thermodynamic data and phase diagram information from literature served as input data for a CALPHAD-type optimization of the Cd–Pr phase diagram. The complete composition range could be described precisely with the present models, both with respect to phase equilibria as well as to thermodynamic input data. The thermodynamic parameters of all intermetallic compounds were modelled following Neumann–Kopp rule. Temperature dependent contributions to the individual Gibbs energies were used for all compounds. Extended solid solubilities are well described for the low- and high-temperature modifications of Pr and also for the intermetallic compound CdPr. A quite good agreement with all viable data available from literature was found and is presented. PMID:25540475

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions.

PubMed

Miyazawa, Kohtaro; Okada, Hiroyuki; Masujin, Kentaro; Iwamaru, Yoshifumi; Yokoyama, Takashi

2015-01-01

Disease-related prion protein (PrP(Sc)), which is a structural isoform of the host-encoded cellular prion protein, is thought to be a causative agent of transmissible spongiform encephalopathies. However, the specific role of PrP(Sc) in prion pathogenesis and its relationship to infectivity remain controversial. A time-course study of prion-affected mice was conducted, which showed that the prion infectivity was not simply proportional to the amount of PrP(Sc) in the brain. Centrifugation (20,000 ×g) of the brain homogenate showed that most of the PrP(Sc) was precipitated into the pellet, and the supernatant contained only a slight amount of PrP(Sc). Interestingly, mice inoculated with the obtained supernatant showed incubation periods that were approximately 15 d longer than those of mice inoculated with the crude homogenate even though both inocula contained almost the same infectivity. Our results suggest that a small population of fine PrP(Sc) may be responsible for prion infectivity and that large, aggregated PrP(Sc) may contribute to determining prion disease duration.

Plant Pathogenesis-Related Proteins PR-10 and PR-14 as Components of Innate Immunity System and Ubiquitous Allergens.

PubMed

Finkina, Ekaterina I; Melnikova, Daria N; Bogdanov, Ivan V; Ovchinnikova, Tatiana V

2017-01-01

Pathogenesis-related (PR) proteins are components of innate immunity system in plants. They play an important role in plant defense against pathogens. Lipid transfer proteins (LTPs) and Bet v 1 homologs comprise of two separate families of PR-proteins. Both LTPs (PR-14) and Bet v 1 homologs (PR-10) are multifunctional small proteins involving in plant response to abiotic and biotic stress conditions. The representatives of these PR-protein families do not show any sequence similarity but have other common biochemical features such as low molecular masses, the presence of hydrophobic cavities, ligand binding properties, and antimicrobial activities. Besides, many members of PR-10 and PR-14 families are ubiquitous plant panallergens which are able to cause sensitization of human immune system and crossreactive allergic reactions to plant food and pollen. This review is aimed at comparative analysis of structure-functional and allergenic properties of the PR-10 and PR-14 families, as well as prospects for their medicinal application. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

MONA, LISA and VINCI Soon Ready to Travel to Paranal

NASA Astrophysics Data System (ADS)

2000-11-01

of this very complex system. Subsequently, it will serve to tune this key research facility to the highest possible performance. The VLTI is based on the combination of light (beams) from the telescopes at Paranal. Of these, the four 8.2-m Unit Telescopes are already in operation - they will soon be joined by three 1.8-m telescopes that can be relocated on rails, cf. PR Photo 43b/99. By means of a system of mirrors, the light from two or more of these telescopes will be guided to the central Interferometric Laboratory , at the center of the observing platform on Paranal. Information about the heart of this complex system, the Delay Lines that are located in the underground Interferometric Tunnel, is available with the recent ESO PR Photos 26a-e/00. The VLTI will later receive other front-line instruments, e.g. AMBER , MIDI and PRIMA. When fully ready some years from now, the VLTI will produce extremely sharp images. This will have a major impact on different types of exciting astronomical observations, e.g.: * the direct discovery and imaging of extra-solar planets comparable to Jupiter, * the discovery and imaging of low-mass stars such as brown dwarfs, * observations of star-forming regions and to better understand the physical processes that give birth to stars, * spectral analysis of the atmospheres of nearby stars, and * imaging the objects of the very core of our Galaxy and the detection of black holes in active nuclei of galaxies. The VINCI test instrument The new instrument, VINCI , will soon be delivered to Paranal by the Département de Recherche Spatiale (Department for Space Research), a joint unit of the Centre Nationale de la Recherche Scientifique (French National Centre for Scientific Research) and the Paris Observatory. VINCI is a functional copy of the FLUOR instrument - now at the IOTA (Infrared Optical Telescope Array) interferometer - that has been upgraded and adapted to the needs of the VLTI. FLUOR was developed by the Département de Recherche

Celestial Fireworks from Dying Stars

NASA Astrophysics Data System (ADS)

2011-04-01

This image of the nebula NGC 3582, which was captured by the Wide Field Imager on the MPG/ESO 2.2-metre telescope at ESO's La Silla Observatory in Chile, shows giant loops of gas bearing a striking resemblance to solar prominences. These loops are thought to have been ejected by dying stars, but new stars are also being born within this stellar nursery. These energetic youngsters emit intense ultraviolet radiation that makes the gas in the nebula glow, producing the fiery display shown here. NGC 3582 is part of a large star-forming region in the Milky Way, called RCW 57. It lies close to the central plane of the Milky Way in the southern constellation of Carina (The Keel of Jason's ship, the Argo). John Herschel first saw this complex region of glowing gas and dark dust clouds in 1834, during his stay in South Africa. Some of the stars forming in regions like NGC 3582 are much heavier than the Sun. These monster stars emit energy at prodigious rates and have very short lives that end in explosions as supernovae. The material ejected from these dramatic events creates bubbles in the surrounding gas and dust. This is the probable cause of the loops visible in this picture. This image was taken through multiple filters. From the Wide Field Imager, data taken through a red filter are shown in green and red, and data taken through a filter that isolates the red glow characteristic of hydrogen are also shown in red. Additional infrared data from the Digitized Sky Survey are shown in blue. The image was processed by ESO using the observational data identified by Joe DePasquale, from the United States [1], who participated in ESO's Hidden Treasures 2010 astrophotography competition [2]. The competition was organised by ESO in October-November 2010, for everyone who enjoys making beautiful images of the night sky using astronomical data obtained using professional telescopes. Notes [1] Joe searched through ESO's archive and identified datasets that he used to compose his

Piperazine derivatives inhibit PrP/PrP(res) propagation in vitro and in vivo.

PubMed

Leidel, Fabienne; Eiden, Martin; Geissen, Markus; Hirschberger, Thomas; Tavan, Paul; Giese, Armin; Kretzschmar, Hans A; Schätzl, Hermann; Groschup, Martin H

2014-02-28

Prion diseases are fatal neurodegenerative disorders, which are not curable and no effective treatment exists so far. The major neuropathological change in diseased brains is the conversion of the normal cellular form of the prion protein PrPc(C) into a disease-associated isoform PrP(Sc). PrP(Sc) accumulates into multimeres and fibrillar aggregates, which leads to the formation of amyloid plaques. Increasing evidence indicates a fundamental role of PrP(Sc) species and its aggregation in the pathogenesis of prion diseases, which initiates the pathological cascade and leads to neurodegeneration accompanied by spongiform changes. In search of compounds that have the potential to interfere with PrP(Sc) formation and propagation, we used a cell based assay for the screening of potential aggregation inhibitors. The assay deals with a permanently prion infected cell line that was adapted for a high-throughput screening of a compound library composed of 10,000 compounds (DIVERset 2, ChemBridge). We could detect six different classes of highly potent inhibitors of PrP(Sc) propagation in vitro and identified piperazine derivatives as a new inhibitory lead structure, which increased incubation time of scrapie infected mice. Copyright © 2014 Elsevier Inc. All rights reserved.

Role of Pr substitution as deoxygenation in suppression of superconductivity in GdPr-123 system

NASA Astrophysics Data System (ADS)

Yamani, Z.; Akhavan, M.

1996-02-01

Predominantly single phase polycrystalline Gd 1- xPr xBa 2Cu 3O 7- y (GdPr-123) samples with 0 ≤ x ≤ 1.0 have been prepared by standard solid state reaction technique and characterized by XRD. The electrical resistivity measurements show the suppression of superconductivity with increasing x. Two plateaus appear in the Tc versus x curve at x ≈ 0-0.05 and at x ≈ 0.15-0.25 followed by a decrease to zero at xcr ≈ 0.45, similar to the plateaus of Tc versus 7 - y curve at 7 - y ≈ 6.8 -7 and at 7 - y ≈ 6.55-6.75 in RBa 2Cu 3O 7 - y ( R-123) ( R: Y or rare earth except Ce, Pr, Pm, Tb) systems. The valency of Pr was determined by magnetization measurements in the temperature range 100 K to 250 K. This data indicates a mixed valence state for Pr ions with an effective magnetic moment μ ≈ 2.69 μB per Pr ion, which yields a valency for Pr of ≈ 3.86 +. For these systems, Tc( x) does not follow the Abrikosov-Gor'kov pair breaking theory. We suggest that the suppression of superconductivity by Pr-substitution can be explained by means of an effective increasing of the oxygen deficiency in the structure, in a similar way to what happens in an R-123 system, when 7 - y is decreased in a controlled manner. This implies that CuO 2 planes are responsible for superconductivity through the effect of chains.

It's Far, It's Small, It's Cool: It's an Icy Exoplanet!

NASA Astrophysics Data System (ADS)

2006-01-01

North (Haleakala, Hawaii, USA). ESO PR Photo 03b/06 ESO PR Photo 03b/06 Light Curve of OGLE-2005-BLG-390 The OGLE (Optical Gravitational Lensing Experiment) search team (led by A. Udalski, Warsaw University Observatory, Poland) discovered the event OGLE-2005-BLG-390 on 11 July 2005, triggering the PLANET telescopes to start taking data. A light curve consistent with a single lens star peaking at an amplification of about 3 on 31 July 2005 was observed, until 10 August when PLANET member Pascal Fouqué, observing at the Danish 1.54m at ESO La Silla, noticed a planetary deviation. An OGLE point from the same night showed the same trend, while the last half of the planetary deviation, lasting about a day, had been covered by images from Perth Observatory. The MOA (Microlensing Observations in Astrophysics) collaboration was later able to identify the source star on its images and confirmed the deviation. No other interpretation than the presented sub-Neptune mass planet with its quoted parameters appeared to fit the extensive data set. This discovery brings a fresh look at the field of planetary science. In particular, astronomers now think that such frozen worlds are much more common than their larger, Jupiter-like brethren. "Indeed if Jupiter-like planets were as widespread, the microlensing method should have found dozens of them by now ", said David Bennett (University of Notre Dame, USA), another PLANET team member. The microlensing technique is most probably the only method currently capable of detecting planets similar to Earth. "The search for a second Earth is the driving force behind our research and this discovery constitutes a major leap forward since it is the most Earth-like planet we know of so far ", said co-author Daniel Kubas, from ESO. ESO PR Video 03/06 ESO PR Video 03/06 Learn more with the video! A report has been published in the 26 January 2006 edition of the leading journal Nature ("Discovery of a cool planet of 5.5 Earth masses through

Next VLT Instrument Ready for the Astronomers

NASA Astrophysics Data System (ADS)

2000-02-01

FORS2 Commissioning Period Successfully Terminated The commissioning of the FORS2 multi-mode astronomical instrument at KUEYEN , the second FOcal Reducer/low dispersion Spectrograph at the ESO Very Large Telescope, was successfully finished today. This important work - that may be likened with the test driving of a new car model - took place during two periods, from October 22 to November 21, 1999, and January 22 to February 8, 2000. The overall goal was to thoroughly test the functioning of the new instrument, its conformity to specifications and to optimize its operation at the telescope. FORS2 is now ready to be handed over to the astronomers on April 1, 2000. Observing time for a six-month period until October 1 has already been allocated to a large number of research programmes. Two of the images that were obtained with FORS2 during the commissioning period are shown here. An early report about this instrument is available as ESO PR 17/99. The many modes of FORS2 The FORS Commissioning Team carried out a comprehensive test programme for all observing modes. These tests were done with "observation blocks (OBs)" that describe the set-up of the instrument and telescope for each exposure in all details, e.g., position in the sky of the object to be observed, filters, exposure time, etc.. Whenever an OB is "activated" from the control console, the corresponding observation is automatically performed. Additional information about the VLT Data Flow System is available in ESO PR 10/99. The FORS2 observing modes include direct imaging, long-slit and multi-object spectroscopy, exactly as in its twin, FORS1 at ANTU . In addition, FORS2 contains the "Mask Exchange Unit" , a motorized magazine that holds 10 masks made of thin metal plates into which the slits are cut by means of a laser. The advantage of this particular observing method is that more spectra (of more objects) can be taken with a single exposure (up to approximately 80) and that the shape of the slits can be

The Gobbling Dwarf that Exploded

NASA Astrophysics Data System (ADS)

2007-07-01

A unique set of observations, obtained with ESO's VLT, has allowed astronomers to find direct evidence for the material that surrounded a star before it exploded as a Type Ia supernova. This strongly supports the scenario in which the explosion occurred in a system where a white dwarf is fed by a red giant. ESO PR Photo 31a/07 ESO PR Photo 31a/07 Evolution of SN 2006X Spectrum Because Type Ia supernovae are extremely luminous and quite similar to one another, these exploding events have been used extensively as cosmological reference beacons to trace the expansion of the Universe. However, despite significant recent progress, the nature of the stars that explode and the physics that governs these powerful explosions have remained very poorly understood. In the most widely accepted models of Type Ia supernovae the pre-explosion white dwarf star orbits another star. Due to the close interaction and the strong attraction produced by the very compact object, the companion star continuously loses mass, 'feeding' the white dwarf. When the mass of the white dwarf exceeds a critical value, it explodes. The team of astronomers studied in great detail SN 2006X, a Type Ia supernova that exploded 70 million light-years away from us, in the splendid spiral Galaxy Messier 100 (see ESO 08/06). Their observations led them to discover the signatures of matter lost by the normal star, some of which is transferred to the white dwarf. The observations were made with the Ultraviolet and Visual Echelle Spectrograph (UVES), mounted at ESO's 8.2-m Very Large Telescope, on four different occasions, over a time span of four months. A fifth observation at a different time was secured with the Keck telescope in Hawaii. The astronomers also made use of radio data obtained with NRAO's Very Large Array as well as images extracted from the NASA/ESA Hubble Space Telescope archive. ESO PR Photo 31b/07 ESO PR Photo 31b/07 SN 2006X, before and after the Type Ia Supernova explosion "No Type Ia

Spectroscopic investigations on Pr³+ and Nd³+ doped strontium-lithium-bismuth borate glasses.

PubMed

Rajesh, D; Balakrishna, A; Seshadri, M; Ratnakaram, Y C

2012-11-01

Spectroscopic investigations on different concentrations (0.1, 0.5, 1.0, 1.5 and 2.0mol%) of Pr(3+) and Nd(3+) doped strontium lithium bismuth borate glasses have been done. X-ray diffraction, SEM with EDS, absorption and luminescence spectra were recorded for all the glass matrices and analyzed. X-ray diffraction profiles and SEM images conformed amorphous nature of investigated glass samples. EDS spectra of host glass and Pr(3+)doped glass matrices gave information about the chemical composition of glass samples. From the absorption spectra of Pr(3+) and Nd(3+) ions, Judd-Ofelt (J-O) intensity parameters (Ω(λ),λ=2, 4 and 6) have been calculated and compared with other glass matrices. The emission characteristics such as radiative lifetimes (τ(R)), measured and calculated branching ratios (β) and stimulated emission cross-sections (σ(P)) have been obtained for the observed emission transitions of Pr(3+) and Nd(3+) ions in the above glass matrix for all the concentrations. From the emission spectra of Pr(3+) and Nd(3+) doped glass matrices, the effect of concentration on the quenching of intensity of (1)D(2)→(3)H(4) transition of Pr(3+) ion and (4)F(3/2)→(4)I(9/2), (4)I(11/2) and (4)I(13/2) transitions of Nd(3+) have been studied and discussed. Copyright © 2012 Elsevier B.V. All rights reserved.

Distant Supernovae Indicate Ever-Expanding Universe

NASA Astrophysics Data System (ADS)

1998-12-01

,000 million light-years) is observed on five dates with the SUSI camera at the 3.6-m New Technology Telescope (NTT). The host galaxy is clearly visible and the supernova reaches its maximum brightness around 13 March 1997, after which it fades. In PR Photo 50b/98 of another supernova that was found at the same time, the image of the host galaxy is barely visible, most probably because it is a low surface brightness galaxy . Here, the redshift of the supernova is z = 0.40 (distance 6,000 million light-years) and the brightness peaks around 16 March 1997. Technical information: All images were obtained through an R (red) optical filtre. The image quality varies somewhat from image to image. Exposure times and seeing values: Photo 50a/98 - 11 March (300 sec; 0.73 arcsec); 13 March (600 sec; 0.79 arcsec); 16 March (600 sec; 0.72 arcsec); 29 March (1200 sec; 1.17 arcsec); 5 April (300 sec; 0.55 arcsec) and Photo 50b/98 - 11 March (300 sec; 0.50 arcsec); 13 March (600 sec; 0.81 arcsec); 16 March (600 sec; 0.90 arcsec); 29 March (1200 sec; 0.83 arcsec); 7 April (300 sec; 1.43 arcsec); 7 May (1800 sec; 1.22 arcsec). These explosions, known as Type Ia Supernovae , are distinguished by their very uniform properties, including their intrinsic brightness; this makes them ideal for the measurement of large distances, cf. ESO PR Photos 50a/98 and 50b/98 , as well as ESO Press Release 09/95. It is by means of observations of remote objects of this type that the all-important distances could be determined with sufficient accuracy. In particular, coordinated observing campaigns of Type Ia Supernovae were carried out at several of the world's major observatories. In this way it became possible to secure the crucial data that provide the basis of the new analysis. Distances to Type Ia Supernovae are larger than expected The new observations show that, compared to their nearby twins, distant supernovae appear too dim, even for a Universe which has been freely coasting (i.e. with no change of the

Scintillation properties of selected oxide monocrystals activated with Ce and Pr

NASA Astrophysics Data System (ADS)

Wojtowicz, Andrzej J.; Drozdowski, Winicjusz; Wisniewski, Dariusz; Lefaucheur, Jean-Luc; Galazka, Zbigniew; Gou, Zhenhui; Lukasiewicz, Tadeusz; Kisielewski, Jaroslaw

2006-01-01

In the last 10-15 years there has been a significant effort toward development of new, more efficient and faster materials for detection of ionizing radiation. A growing demand for better scintillator crystals for detection of 511 keV gamma particles has been due mostly to recent advances in modern imaging systems employing positron emitting radionuclides for medical diagnostics in neurology, oncology and cardiology. While older imaging systems were almost exclusively based on BGO and NaI:Tl crystals the new systems, e.g., ECAT Accel, developed by Siemens/CTI, are based on recently discovered and developed LSO (Lu 2SiO 5:Ce, Ce-activated lutetium oxyorthosilicate) crystals. Interestingly, despite very good properties of LSO, there still is a strong drive toward development of new scintillator crystals that would show even better performance and characteristics. In this presentation we shall review spectroscopic and scintillator characterization of new complex oxide crystals, namely LSO, LYSO, YAG, LuAP (LuAlO 3, lutetium aluminate perovskite) and LuYAP activated with Ce and Pr. The LSO:Ce crystals have been grown by CTI Inc (USA), LYSO:Ce, LuAP:Ce and LuYAP:Ce crystals have been grown by Photonic Materials Ltd., Scotland (PML is the only company providing large LuAP:Ce crystals on a commercial scale), while YAG:Pr and LuAP:Pr crystals have been grown by Institute of Electronic Materials Technology (Poland). All these crystals have been characterized at Institute of Physics, N. Copernicus University (Poland). We will review and compare results of measurements of radioluminescence, VUV spectroscopy, scintillation light yields, scintillation time profiles and low temperature thermoluminescence performed on these crystals. We will demonstrate that all experiments clearly indicate that there is a significant room for improvement of LuAP, LuYAP and YAG. While both Ce-activated LSO and LYSO perform very well, we also note that LuYAP:Ce, LuAP:Ce and YAG:Pr offer some

A Solar Mini-Eclipse on May 7, 2003

NASA Astrophysics Data System (ADS)

2003-06-01

dark spot moving across the bright solar disk. There are about 13 Mercury transits each century and they follow in time intervals of approximately 13, 7, 10 and 3 years. The most recent one took place in November 1999 and the next will be on May 7, 2003 and November 8, 2006 . The next Mercury transit happens on Wednesday morning next week . It lasts from about 7:13 hrs CEST (Central European Summer Time) until 12:32 hrs CEST (5:13 to 10:32 UT) and the contour of the small planet as it moves across the solar disk can be seen from all places where the Sun is above the horizon and the sky is clear. The best observing conditions are from Europe, Africa and Asia. Observations of the transit Note, however, that this event cannot be observed with the unaided eye - this would also be extremely dangerous because the enormous brightness of the Sun will cause total blindness in a fraction of a second! Observations can only be made by means of telescopes which project the solar image onto a white screen. Public observatories, planetaria and other educational institutions will arrange special events on this occasion. News about such arrangements will appear in the local press. Live images on the web On this special occasion and in order to provide for everybody the chance to watch this event, the European Southern Observatory (ESO) and the European Association for Astronomy Education (EAAE) , together with the Institut de Mécanique Céleste et de Calcul des Éphémérides (IMCCE) and the Observatoire de Paris in France, are providing live images and a running commentary for all interested parties. It is also planned to display images obtained at observatories in the Belgium, the Czech Republic, Hungary, Italy and Spain, and possibly others. The availability will depend on the weather situation in the various places. ESO PR Photo 11b/03 ESO PR Photo 11b/03 [Normal - JPEG: 600 x 497 pix - 256k] Caption : The view through a large telescope may offer scenes like this one, when the

Imaging characteristics of scintimammography using parallel-hole and pinhole collimators

NASA Astrophysics Data System (ADS)

Tsui, B. M. W.; Wessell, D. E.; Zhao, X. D.; Wang, W. T.; Lewis, D. P.; Frey, E. C.

1998-08-01

The purpose of the study is to investigate the imaging characteristics of scintimammography (SM) using parallel-hole (PR) and pinhole (PN) collimators in a clinical setting. Experimental data were acquired from a phantom that models the breast with small lesions using a low energy high resolution (LEHR) PR and a PN collimator. At close distances, the PN collimator provides better spatial resolution and higher detection efficiency than the PR collimator, at the expense of a smaller field-of-view (FOV). Detection of small breast lesions can be further enhanced by noise smoothing, field uniformity correction, scatter subtraction and resolution recovery filtering. Monte Carlo (MC) simulation data were generated from the 3D MCAT phantom that realistically models the Tc-99m sestamibi uptake and attenuation distributions in an average female patient. For both PR and PN collimation, the scatter to primary ratio (S/P) decreases from the base of the breast to the nipple and is higher in the left than right breast due to scatter of photons from the heart. Results from the study add to understanding of the imaging characteristics of SM using PR and PN collimators and assist in the design of data acquisition and image processing methods to enhance the detection of breast lesions using SM.

HIV-negative male couples' attitudes about pre-exposure prophylaxis (PrEP) and using PrEP with a sexual agreement.

PubMed

Mitchell, Jason W; Lee, Ji-Young; Woodyatt, Cory; Bauermeister, José; Sullivan, Patrick; Stephenson, Rob

2016-08-01

One efficacious strategy to help prevent HIV is oral pre-exposure prophylaxis (PrEP), a daily regimen of antiretroviral treatment taken by HIV-negative individuals. Two of the recommendations of Centers for Disease Control and Prevention (CDC) guidelines for PrEP pertain to being in a relationship (i.e., male couples). Despite the recognition of how primary partners in male couples' relationships shape HIV risk and CDC's PrEP guidelines, there is a paucity of data that examine HIV-negative male couples' attitudes toward PrEP use and using PrEP with a sexual agreement. A sexual agreement is an explicit agreement made between two individuals about what sex and other related behaviors may occur within and outside of their relationship. In this qualitative study, we examine HIV-negative male couples' attitudes toward PrEP use and whether they thought PrEP could be integrated into a sexual agreement. Data for this study are drawn from couple-level interviews conducted in 2014 with 29 HIV-negative male couples who had a sexual agreement and were from Atlanta or Detroit. Both passive (e.g., flyers) and active (e.g., targeted Facebook advertisements) recruitment methods were used; the sample was stratified by agreement type. Thematic analysis was applied to identify the following themes regarding HIV-negative male couples' attitudes toward PrEP use: (1) PrEP and condom use; (2) concerns about PrEP (e.g., effectiveness, side effects, and promoting sexually risky behavior); and (3) accessibility of PrEP. Some thought PrEP could be a part of couples' agreement because it could help reduce sexual anxiety and sexual risk, and would help keep the couple safe. Others described PrEP use with an agreement as something for "others". Some were also concerned that incorporating PrEP could usurp the need for a sexual agreement in a couples' relationship. These themes highlight the need to improve informational messaging and promotion efforts about PrEP among HIV-negative male couples

The Gaia-ESO Survey: evidence of atomic diffusion in M67?

NASA Astrophysics Data System (ADS)

Bertelli Motta, C.; Pasquali, A.; Richer, J.; Michaud, G.; Salaris, M.; Bragaglia, A.; Magrini, L.; Randich, S.; Grebel, E. K.; Adibekyan, V.; Blanco-Cuaresma, S.; Drazdauskas, A.; Fu, X.; Martell, S.; Tautvaišienė, G.; Gilmore, G.; Alfaro, E. J.; Bensby, T.; Flaccomio, E.; Koposov, S. E.; Korn, A. J.; Lanzafame, A. C.; Smiljanic, R.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Damiani, F.; Franciosini, E.; Heiter, U.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2018-07-01

Investigating the chemical homogeneity of stars born from the same molecular cloud at virtually the same time is very important for our understanding of the chemical enrichment of the interstellar medium and with it the chemical evolution of the Galaxy. One major cause of inhomogeneities in the abundances of open clusters is stellar evolution of the cluster members. In this work, we investigate variations in the surface chemical composition of member stars of the old open cluster M67 as a possible consequence of atomic diffusion effects taking place during the main-sequence phase. The abundances used are obtained from high-resolution UVES/FLAMES spectra within the framework of the Gaia-ESO Survey. We find that the surface abundances of stars on the main sequence decrease with increasing mass reaching a minimum at the turn-off. After deepening of the convective envelope in subgiant branch stars, the initial surface abundances are restored. We found the measured abundances to be consistent with the predictions of stellar evolutionary models for a cluster with the age and metallicity of M67. Our findings indicate that atomic diffusion poses a non-negligible constraint on the achievable precision of chemical tagging methods.

Detailed studies om three open clusters from Gaia ESO Survey (GES)

NASA Astrophysics Data System (ADS)

Balaguer-Núnez, L.; Casamiquela, L.; Jordana, N.; Massana, P.; Jordi, C.; Masana, E.

2017-03-01

We present results for the intermediate-age and old open clusters NGC 6633, NGC 6705 (M 11) and NGC 2682 (M 67). We have used new Str ̈omgren-Crawford photometry, proper motions from ROA observations and spectral information from Gaia-ESO Survey (GES), to study the physical parameters of the stars in the three cluster's areas. The astrometric studies cover an area of about 1°x2° and down to r' ˜ 17 while our INT-WFC CCD intermediate-band photometry covers an area of about 40'x40' down to V ˜ 19. The stars of those areas selected as cluster members from their proper motions, are classified into photometric regions and their physical parameters determined, using uvbyHβ photometry and standard relations among colour indices for each of the photometric regions of the HR diagram. That allows us to determine reddening, distances, absolute magnitudes, spectral types, effective temperatures, gravities and metallicities, thus providing an astrophysical characterization of the clusters. These results are compared with the physical parameters obtained from GES spectral data as well as radial velocities to confirm membership. All these data lead us to a comparison of photometric and spectroscopic physical parameters.

The Gaia-ESO Survey: Evidence of atomic diffusion in M67?

NASA Astrophysics Data System (ADS)

Motta, C. Bertelli; Pasquali, A.; Richer, J.; Michaud, G.; Salaris, M.; Bragaglia, A.; Magrini, L.; Randich, S.; Grebel, E. K.; Adibekyan, V.; Blanco-Cuaresma, S.; Drazdauskas, A.; Fu, X.; Martell, S.; TautvaišienÄ--, G.; Gilmore, G.; Alfaro, E. J.; Bensby, T.; Flaccomio, E.; Koposov, S. E.; Korn, A. J.; Lanzafame, A. C.; Smiljanic, R.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Damiani, F.; Franciosini, E.; Heiter, U.; Hourihane, A.; Jofré, P.; Lardo, C.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2018-04-01

Investigating the chemical homogeneity of stars born from the same molecular cloud at virtually the same time is very important for our understanding of the chemical enrichment of the interstellar medium and with it the chemical evolution of the Galaxy. One major cause of inhomogeneities in the abundances of open clusters is stellar evolution of the cluster members. In this work, we investigate variations in the surface chemical composition of member stars of the old open cluster M67 as a possible consequence of atomic diffusion effects taking place during the main-sequence phase. The abundances used are obtained from high-resolution UVES/FLAMES spectra within the framework of the Gaia-ESO Survey. We find that the surface abundances of stars on the main sequence decrease with increasing mass reaching a minimum at the turn-off. After deepening of the convective envelope in sub-giant branch stars, the initial surface abundances are restored. We found the measured abundances to be consistent with the predictions of stellar evolutionary models for a cluster with the age and metallicity of M67. Our findings indicate that atomic diffusion poses a non-negligible constraint on the achievable precision of chemical tagging methods.

Revisiting the Orion Nebula

NASA Astrophysics Data System (ADS)

2004-06-01

ESO/MPG 2.2m telescope at La Silla, to obtain very deep images of this region. ESO PR Photo 20/04 shows a false-colour composite of images obtained in four different wavebands (see technical information below). Among others, these observations allow the astronomers to measure the rates of mass that falls onto the young stars (the mass accretion rates) and to determine if it depends on the position of the stars in the cluster. If this were the case, it would indicate that the final stages of star formation are affected by the onset of ionising radiation from the most massive stars. From a preliminary study with the Hubble Space Telescope, the astronomers found that indeed the mass accretion rates are lower in the Orion Nebula Cluster than in other, more diffuse star-forming regions. The analysis of these new WFI images should allow confirmation of this hypothesis. The astronomers also obtained images of the Orion Nebula in several narrow-band filters corresponding to emission lines - hydrogen (Halpha), oxygen ([OIII]), and sulphur ([SII]) - enabling them to probe the morphology of the nebula in these prominent lines. It is rather obvious from the image that for example some regions are redder than others, providing the astronomers with important clues on the conditions prevailing in the nebula. In the next months, a large international collaboration also led by M. Robberto will use the Hubble Space Telescope to survey with unprecedented sensitivity (23-25 mag) and spatial resolution approximately 50% of the field imaged by the present WFI observations. The astronomers expect to discover and classify an unknown but substantial population of young double stars, low mass stars and brown dwarfs.

Factors associated with body image dissatisfaction among adolescents in public schools students in Salvador, Brazil.

PubMed

Santana, Mônica L P; Silva, Rita de Cássia R; Assis, Ana M O; Raich, Rosa M; Machado, Maria Ester P C; de J Pinto, Elizabete; de Moraes, Lia T L P; Ribeiro Júnior, Hugo da C

2013-01-01

To identify the prevalence of body image dissatisfaction and associated factors among students in Salvador, Brazil. A cross-sectional study involving a random sample of 1,494 (852 girls and 642 boys) adolescents between 11 and 17 years of age who were students in the public schools in Salvador, Brazil. Participants completed the Body Shape Questionnaire and the Eating Attitudes Test-26. Body image was characterized as satisfactory or unsatisfactory. We obtained demographic, anthropometric and economic information and information regarding the stage of maturation, self-perception of body weight, and consumption of sweetened beverages and diet soft drinks. To identify associated factors we used Poisson regression analysis. Body image dissatisfaction was present in 19.5% of the adolescents, with a prevalence of 26.6% among the girls and 10% among the boys. Independent of sex, the prevalence of body image dissatisfaction was higher among adolescents who were overweight or obese (girls, PR: 1.38, CI: 1.09-1.73 and boys, PR: 2.26, CI: 1.08-4.75), higher among those who perceived themselves as fat (girls, PR: 2.85, CI: 2.07-3.93 and boys, PR: 3.17, CI: 1.39-7.23), and higher among those who had negative attitudes toward eating (girls, PR: 2.42, CI: 1.91-3.08 and boys, PR: 4.67, CI: 2.85-7.63).. A reduction in body image dissatisfaction was only identified among underweight girls (PR: 0.12, CI: 0.03-0.49). A high occurrence of body image dissatisfaction was observed among the adolescents, and biological and behavioral factors were associated with this dissatisfaction. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.