Science.gov

Sample records for implementing high availability

  1. Implementation and use of a highly available and innovative IaaS solution: the Cloud Area Padovana

    NASA Astrophysics Data System (ADS)

    Aiftimiei, C.; Andreetto, P.; Bertocco, S.; Biasotto, M.; Dal Pra, S.; Costa, F.; Crescente, A.; Dorigo, A.; Fantinel, S.; Fanzago, F.; Frizziero, E.; Gulmini, M.; Michelotto, M.; Sgaravatto, M.; Traldi, S.; Venaruzzo, M.; Verlato, M.; Zangrando, L.

    2015-12-01

    While in the business world the cloud paradigm is typically implemented purchasing resources and services from third party providers (e.g. Amazon), in the scientific environment there's usually the need of on-premises IaaS infrastructures which allow efficient usage of the hardware distributed among (and owned by) different scientific administrative domains. In addition, the requirement of open source adoption has led to the choice of products like OpenStack by many organizations. We describe a use case of the Italian National Institute for Nuclear Physics (INFN) which resulted in the implementation of a unique cloud service, called ’Cloud Area Padovana’, which encompasses resources spread over two different sites: the INFN Legnaro National Laboratories and the INFN Padova division. We describe how this IaaS has been implemented, which technologies have been adopted and how services have been configured in high-availability (HA) mode. We also discuss how identity and authorization management were implemented, adopting a widely accepted standard architecture based on SAML2 and OpenID: by leveraging the versatility of those standards the integration with authentication federations like IDEM was implemented. We also discuss some other innovative developments, such as a pluggable scheduler, implemented as an extension of the native OpenStack scheduler, which allows the allocation of resources according to a fair-share based model and which provides a persistent queuing mechanism for handling user requests that can not be immediately served. Tools, technologies, procedures used to install, configure, monitor, operate this cloud service are also discussed. Finally we present some examples that show how this IaaS infrastructure is being used.

  2. Design and implementation of a robust high-availability DICOM print network in a large multimodality clinical environment

    NASA Astrophysics Data System (ADS)

    Shepard, S. Jeff; Thompson, Stephen K.; Krugh, Kerry T.; Venable, Steve; Munden, Regginald

    2002-05-01

    This work will describe the implementation of a highly reliable DICOM print network at our institution. The system was designed to provide DICOM print services to many modalities, allowing customized LUT assignments either by calling AET or by special request from the modality. The system was implemented on a small scale with hardware from three different manufacturers (Agfa/Sterling, Kodak, and Fuji) for evaluation purposes. Our experiences with each system will be presented. The final configuration (Fuji PS551/DPL) was scaled up to meet the needs for hard copy production in our busy (300,000 exams/year) clinical operation. Quality control is accomplished via automatic (chron job) initiation of DICOM print jobs from a Unix-based workstation or by manual initiation from one of several PC's utilizing e-Film'sTM DICOM print capabilities. Print servers are connected to multiple printers and are configured for automatic fail-over on printer error detection. Modalities are configured with dual ('Primary' and 'Secondary') print destinations to allow manual redirection of print activity on print server error detection. As a result, the system provides an extremely high level of dependability. The printers also sort by AET so that the output from any given modality may be directed to a specific sorting bin, significantly reducing the effort needed to sort films and match with paperwork prior to hanging.

  3. High Availability Electronics Standards

    SciTech Connect

    Larsen, R.S.; /SLAC

    2006-12-13

    Availability modeling of the proposed International Linear Collider (ILC) predicts unacceptably low uptime with current electronics systems designs. High Availability (HA) analysis is being used as a guideline for all major machine systems including sources, utilities, cryogenics, magnets, power supplies, instrumentation and controls. R&D teams are seeking to achieve total machine high availability with nominal impact on system cost. The focus of this paper is the investigation of commercial standard HA architectures and packaging for Accelerator Controls and Instrumentation. Application of HA design principles to power systems and detector instrumentation are also discussed.

  4. High availability using virtualization

    NASA Astrophysics Data System (ADS)

    Calzolari, Federico

    2009-10-01

    High availability has always been one of the main problems for a data center. Till now high availability was achieved by host per host redundancy, a highly expensive method in terms of hardware and human costs. A new approach to the problem can be offered by virtualization. Using virtualization, it is possible to achieve a redundancy system for all the services running on a data center. This new approach to high availability allows to share the running virtual machines over the servers up and running, by exploiting the features of the virtualization layer: start, stop and move virtual machines between physical hosts. The system (3RC) is based on a finite state machine with hysteresis, providing the possibility to restart each virtual machine over any physical host, or reinstall it from scratch. A complete infrastructure has been developed to install operating system and middleware in a few minutes. To virtualize the main servers of a data center, a new procedure has been developed to migrate physical to virtual hosts. The whole Grid data center SNS-PISA is running at the moment in virtual environment under the high availability system. As extension of the 3RC architecture, several storage solutions have been tested to store and centralize all the virtual disks, from NAS to SAN, to grant data safety and access from everywhere. Exploiting virtualization and ability to automatically reinstall a host, we provide a sort of host on-demand, where the action on a virtual machine is performed only when a disaster occurs.

  5. High availability using virtualization

    NASA Astrophysics Data System (ADS)

    Calzolari, Federico; Arezzini, Silvia; Ciampa, Alberto; Mazzoni, Enrico; Domenici, Andrea; Vaglini, Gigliola

    2010-04-01

    High availability has always been one of the main problems for a data center. Till now high availability was achieved by host per host redundancy, a highly expensive method in terms of hardware and human costs. A new approach to the problem can be offered by virtualization. Using virtualization, it is possible to achieve a redundancy system for all the services running on a data center. This new approach to high availability allows the running virtual machines to be distributed over a small number of servers, by exploiting the features of the virtualization layer: start, stop and move virtual machines between physical hosts. The 3RC system is based on a finite state machine, providing the possibility to restart each virtual machine over any physical host, or reinstall it from scratch. A complete infrastructure has been developed to install operating system and middleware in a few minutes. To virtualize the main servers of a data center, a new procedure has been developed to migrate physical to virtual hosts. The whole Grid data center SNS-PISA is running at the moment in virtual environment under the high availability system.

  6. High Availability in Optical Networks

    NASA Astrophysics Data System (ADS)

    Grover, Wayne D.; Wosinska, Lena; Fumagalli, Andrea

    2005-09-01

    Call for Papers: High Availability in Optical Networks Submission Deadline: 1 January 2006 The Journal of Optical Networking (JON) is soliciting papers for a feature Issue pertaining to all aspects of reliable components and systems for optical networks and concepts, techniques, and experience leading to high availability of services provided by optical networks. Most nations now recognize that telecommunications in all its forms -- including voice, Internet, video, and so on -- are "critical infrastructure" for the society, commerce, government, and education. Yet all these services and applications are almost completely dependent on optical networks for their realization. "Always on" or apparently unbreakable communications connectivity is the expectation from most users and for some services is the actual requirement as well. Achieving the desired level of availability of services, and doing so with some elegance and efficiency, is a meritorious goal for current researchers. This requires development and use of high-reliability components and subsystems, but also concepts for active reconfiguration and capacity planning leading to high availability of service through unseen fast-acting survivability mechanisms. The feature issue is also intended to reflect some of the most important current directions and objectives in optical networking research, which include the aspects of integrated design and operation of multilevel survivability and realization of multiple Quality-of-Protection service classes. Dynamic survivable service provisioning, or batch re-provisioning is an important current theme, as well as methods that achieve high availability at far less investment in spare capacity than required by brute force service path duplication or 100% redundant rings, which is still the surprisingly prevalent practice. Papers of several types are envisioned in the feature issue, including outlook and forecasting types of treatments, optimization and analysis, new

  7. 77 FR 51619 - Source Specific Federal Implementation Plan for Implementing Best Available Retrofit Technology...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... Implementation Plan for Implementing Best Available Retrofit Technology for Four Corners Power Plant: Navajo... for Implementing Best Available Retrofit Technology for Four Corners Power Plant: Navajo Nation AGENCY... promulgating a source-specific Federal Implementation Plan (FIP) requiring the Four Corners Power Plant...

  8. A novel wavelength availability advertisement based ASON routing protocol implementation

    NASA Astrophysics Data System (ADS)

    Li, Jian; Liu, Juan; Zhang, Jie; Gu, Wanyi

    2005-11-01

    A novel wavelength availability advertisement based ASON routing protocol implementation is proposed in this paper which is derived from Open Shortest Path First protocol (OSPF) version 2. It can be applied to ASON network with a single control domain and can be easily extended to support routing in the multi-domain scenarios. Two new types of link state advertisement (LSA) are suggested for disseminating wavelength availability and network topology information. The OSPF mechanisms are inherited to ensure that the routing messages are delivered more reliably and converged more quickly while with fewer overheads. The topology auto discovery is realized through LSA flooding interacting with auto neighbor discovery using Link Management Protocol. The new LSA formats are given and how the link state database (LSD) is comprised is described. The new data structures proposed include topology resource list, adjacency list and route table. Then we analyze the differences of ASON in link state exchange, routing information flooding procedure, flushing procedure and new resources participating, i.e. new links or nodes join in an existing ASON. The link or node failure and recovery effect and how to deal with them are settled as well. In order to adopt different Routing and Wavelength Assignment (RWA) algorithms, a standard and efficient interface is designed. After extensive simulation we give the numerical analysis and come to the following conclusions: wavelength availability information flooding Convergence Time is about 30 milliseconds and it is not affected by RWA algorithms and the call traffic load; routing Protocol Average Overhead rises linearly with the increase of traffic load; Average Connection Setup Time decreases with the increase of traffic load because of the decrease of Average Routing Distance of the successfully lightpaths; Wavelength availability advertisement can greatly promote the blocking performance of ASON in relatively low traffic load; ASON

  9. Implementation and Validation of Uncertainty Analysis of Available Energy and Available Power

    SciTech Connect

    Jon P. Christophersen; John L. Morrison; B. J. Schubert; Shawn Allred

    2007-04-01

    The Idaho National Laboratory does extensive testing and evaluation of state-of-the-art batteries and ultracapacitors for hybrid-electric vehicle applications as part of the FreedomCAR and Vehicle Technologies Program. Significant parameters of interest include Available Energy and Available Power. Documenting the uncertainty analysis of these derived parameters is a very complex problem. The error is an unknown combination of both linearity and offset; the analysis presented in this paper computes the uncertainty both ways and then the most conservative method is assumed (which is the worst case scenario). Each method requires the use of over 134 equations, some of which are derived and some are measured values. This includes the measurement device error (calibration error) and bit resolution and analog noise error (standard deviation error). The implementation of these equations to acquire a closed form answer was done using Matlab (an array based programming language) and validated using Monte Carlo simulations.

  10. GPS time transfer with implementation of selective availability

    NASA Technical Reports Server (NTRS)

    Allan, David W.; Granveaud, Michel P.; Klepczynski, William J.; Lewandowski, Wlodzimierz W.

    1990-01-01

    The international community of time metrology is facing a major challenge with the Selective Availability (SA) degradation of GPS satellite signals. At present there are 6 Block 1 satellites and 8 Block 2 satellites operating. According to the policy of the U.S. Department of Defence the Block 1 satellite signals will not be degraded, but these satellites are old with a finite life. The Block 2 satellites, which have all been launched since 1988, were subject to Selective Availability from March 25, 1990. The effect of SA should be to limit precision to about 100 meters for navigation and 167 ns for timing. A study was conducted in order to understand the nature of the actual introduced degradation, and to elaborate the means of removing the effects of this degradation on time transfer. This study concerns the time extraction from GPS satellites at NIST, USNO and Paris Observatory, and the comparison of atomic clocks between these laboratories by common view approach. The results show that when using the data taken over several days the time extraction can be achieved with uncertainty of a few tens of nanoseconds, while strict common-view has removed entirely the effects of SA during the periods under study.

  11. Digitally Controlled High Availability Power Supply

    SciTech Connect

    MacNair, David; /SLAC

    2008-09-25

    This paper reports the design and test results on novel topology, high-efficiency, and low operating temperature, 1,320-watt power modules for high availability power supplies. The modules permit parallel operation for N+1 redundancy with hot swap capability. An embedded DSP provides intelligent start-up and shutdown, output regulation, general control and fault detection. PWM modules in the DSP drive the FET switches at 20 to 100 kHz. The DSP also ensures current sharing between modules, synchronized switching, and soft start up for hot swapping. The module voltage and current have dedicated ADCs (>200 kS/sec) to provide pulse-by-pulse output control. A Dual CAN bus interface provides for low cost redundant control paths. Over-rated module components provide high reliability and high efficiency at full load. Low on-resistance FETs replace conventional diodes in the buck regulator. Saturable inductors limit the FET reverse diode current during switching. The modules operate in a two-quadrant mode, allowing bipolar output from complimentary module groups. Controllable, low resistance FETs at the input and output provide fault isolation and allow module hot swapping.

  12. Digitally Controlled High Availability Power Supply

    SciTech Connect

    MacNair, David; /SLAC

    2009-05-07

    This paper will report on the test results of a prototype 1320 watt power module for a high availability power supply. The module will allow parallel operation for N+1 redundancy with hot swap capability. The two quadrant output of each module allows pairs of modules to provide a 4 quadrant (bipolar) operation. Each module employs a novel 4 FET buck regulator arranged in a bridge configuration. Each side of the bridge alternately conducts through a small saturable ferrite that limits the reverse current in the FET body diode during turn off. This allows hard switching of the FETs with low switching losses. The module is designed with over-rated components to provide high reliability and better then 97% efficiency at full load. The modules use a Microchip DSP for control, monitoring, and fault detection. The switching FETS are driven by PWM modules in the DSP at 60 KHz. A Dual CAN bus interface provides for low cost redundant control paths. The DSP will also provide current sharing between modules, synchronized switching, and soft start up for hot swapping. The input and output of each module have low resistance FETs to allow hot swapping and isolation of faulted units.

  13. High Available COTS Based Computer for Space

    NASA Astrophysics Data System (ADS)

    Hartmann, J.; Magistrati, Giorgio

    2015-09-01

    The availability and reliability factors of a system are central requirements of a target application. From a simple fuel injection system used in cars up to a flight control system of an autonomous navigating spacecraft, each application defines its specific availability factor under the target application boundary conditions. Increasing quality requirements on data processing systems used in space flight applications calling for new architectures to fulfill the availability, reliability as well as the increase of the required data processing power. Contrary to the increased quality request simplification and use of COTS components to decrease costs while keeping the interface compatibility to currently used system standards are clear customer needs. Data processing system design is mostly dominated by strict fulfillment of the customer requirements and reuse of available computer systems were not always possible caused by obsolescence of EEE-Parts, insufficient IO capabilities or the fact that available data processing systems did not provide the required scalability and performance.

  14. 77 FR 43205 - Notice of Data Availability for Approval, Disapproval and Promulgation of Implementation Plans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... Implementation Plans; State of Wyoming; Regional Haze State Implementation Plan; Federal Implementation Plan for Regional Haze AGENCY: Environmental Protection Agency. ACTION: Notice of data availability (NODA). SUMMARY..., 2011, that addresses regional haze. (Docket ID No. EPA-R08- OAR-2012-0026). This information...

  15. Regular Soda Policies, School Availability, and High School Student Consumption

    PubMed Central

    Terry-McElrath, Yvonne M.; Chriqui, Jamie F.; O’Malley, Patrick M.; Chaloupka, Frank J.; Johnston, Lloyd D.

    2014-01-01

    Background Beginning in the 2014–2015 school year, all U.S. schools participating in federally reimbursable meal programs are required to implement new nutrition standards for items sold in competitive venues. Multilevel mediation modeling examining direct, mediated, and indirect pathways between policy, availability, and student consumption might provide insight into possible outcomes of implementing aspects of the new standards. Purpose To employ multilevel mediation modeling using state- and school district–level policies mandating school soda bans, school soda availability, and student soda consumption. Methods The 2010–2012 Monitoring the Future surveys obtained nationally representative data on high school student soda consumption; school administrators provided school soda availability data. State laws and district policies were compiled and coded. Analyses conducted in 2014 controlled for state-, school-, and student-level characteristics. Results State–district–school models found that state bans were associated with significantly lower school soda availability (c, p<0.05) but district bans showed no significant associations. No significant direct, mediated, or indirect associations between state policy and student consumption were observed for the overall sample. Among African American high school students, state policy was associated directly with significantly lower school soda availability (a, p<0.01), and—indirectly through lower school availability—with significantly lower soda consumption (a*b, p<0.05). Conclusions These analyses indicate state policy focused on regular soda strongly affected school soda availability, and worked through changes in school availability to decrease soda consumption among African American students, but not the overall population. PMID:25576493

  16. 75 FR 23640 - Approval and Promulgation of Implementation Plans; New York Reasonably Available Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... Control Technology and Reasonably Available Control Measures AGENCY: Environmental Protection Agency (EPA... control measure analysis and New York's efforts to meet the reasonably available control technology... inclusion in the State Implementation Plan and made additional commitments to meet the remaining...

  17. A High-Availability, Distributed Hardware Control System Using Java

    NASA Technical Reports Server (NTRS)

    Niessner, Albert F.

    2011-01-01

    Two independent coronagraph experiments that require 24/7 availability with different optical layouts and different motion control requirements are commanded and controlled with the same Java software system executing on many geographically scattered computer systems interconnected via TCP/IP. High availability of a distributed system requires that the computers have a robust communication messaging system making the mix of TCP/IP (a robust transport), and XML (a robust message) a natural choice. XML also adds the configuration flexibility. Java then adds object-oriented paradigms, exception handling, heavily tested libraries, and many third party tools for implementation robustness. The result is a software system that provides users 24/7 access to two diverse experiments with XML files defining the differences

  18. 78 FR 71508 - Availability of Federally-Enforceable State Implementation Plans for All States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... AGENCY 40 CFR Part 52 Availability of Federally-Enforceable State Implementation Plans for All States... forth all requirements of the applicable implementation plan for such State and shall publish notice in... with the Clean Air Act. SIP requirements applicable to all areas are provided in section 110. Part D...

  19. 75 FR 71548 - Availability of Federally-Enforceable State Implementation Plans for All States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... AGENCY 40 CFR Part 52 Availability of Federally-Enforceable State Implementation Plans for All States... setting forth all requirements of the applicable implementation plan for such State and shall publish... consistent with the Clean Air Act. SIP requirements applicable to all areas are provided in section 110....

  20. Implementation of a versatile research data acquisition system using a commercially available medical ultrasound scanner.

    PubMed

    Hemmsen, Martin Christian; Nikolov, Svetoslav Ivanov; Pedersen, Mads Møller; Pihl, Michael Johannes; Enevoldsen, Marie Sand; Hansen, Jens Munk; Jensen, Jørgen Arendt

    2012-07-01

    This paper describes the design and implementation of a versatile, open-architecture research data acquisition system using a commercially available medical ultrasound scanner. The open architecture will allow researchers and clinicians to rapidly develop applications and move them relatively easy to the clinic. The system consists of a standard PC equipped with a camera link and an ultrasound scanner equipped with a research interface. The ultrasound scanner is an easy-to-use imaging device that is capable of generating high-quality images. In addition to supporting the acquisition of multiple data types, such as B-mode, M-mode, pulsed Doppler, and color flow imaging, the machine provides users with full control over imaging parameters such as transmit level, excitation waveform, beam angle, and focal depth. Beamformed RF data can be acquired from regions of interest throughout the image plane and stored to a file with a simple button press. For clinical trials and investigational purposes, when an identical image plane is desired for both an experimental and a reference data set, interleaved data can be captured. This form of data acquisition allows switching between multiple setups while maintaining identical transducer, scanner, region of interest, and recording time. Data acquisition is controlled through a graphical user interface running on the PC. This program implements an interface for third-party software to interact with the application. A software development toolkit is developed to give researchers and clinicians the ability to utilize third-party software for data analysis and flexible manipulation of control parameters. Because of the advantages of speed of acquisition and clinical benefit, research projects have successfully used the system to test and implement their customized solutions for different applications. Three examples of system use are presented in this paper: evaluation of synthetic aperture sequential beamformation, transverse

  1. 77 FR 28338 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available Control Technology for the 1997 8-Hour Ozone National Ambient Air Quality Standard AGENCY... for meeting reasonably available control technology (RACT) for the 1997 8-hour ozone national...

  2. 77 FR 41278 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available Control Technology for the 1997 8-Hour Ozone National Ambient Air Quality Standard AGENCY... meeting reasonably available control technology (RACT) for oxides of nitrogen (NO X ) and volatile...

  3. 78 FR 31459 - Approval and Promulgation of Air Quality Implementation Plans; Connecticut; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...-1-FRL-9817-2] Approval and Promulgation of Air Quality Implementation Plans; Connecticut; Reasonably Available Control Technology Update To Address Control Techniques Guidelines Issued in 2006, 2007, and 2008... establishes and requires Reasonably Available Control Technology (RACT) for several categories of...

  4. 76 FR 40263 - Implementation of Section 304 of the Telecommunications Act of 1996: Commercial Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ...In this document, we adopt new rules designed to improve the operation of the CableCARD regime until a successor solution becomes effective. The Commission has not been fully successful in implementing the command of Section 629 of the Communications Act to ensure the commercial availability of navigation devices used by consumers to access the services of multichannel video programming......

  5. 14 CFR 161.325 - Availability of data and comments on an implemented restriction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Availability of data and comments on an implemented restriction. 161.325 Section 161.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS NOTICE AND APPROVAL OF AIRPORT NOISE AND...

  6. 14 CFR 161.325 - Availability of data and comments on an implemented restriction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Availability of data and comments on an implemented restriction. 161.325 Section 161.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS NOTICE AND APPROVAL OF AIRPORT NOISE AND...

  7. Implementation and Evaluation of a Condom Availability Program on a College Campus: Lessons from the Field

    ERIC Educational Resources Information Center

    Eastman-Mueller, Heather P.; Gomez-Scott, Jessica R.; Jung, Ae-Kyung; Oswalt, Sara B.; Hagglund, Kristofer

    2016-01-01

    The U.S. Centers for Disease Control and Prevention advocate access to condoms as a critical sexual health prevention strategy. The purpose of this article is to discuss the implementation and evaluation of a condom availability program using dispensing machines in residence halls at a Midwestern U.S. university. Undergraduate students (N = 337)…

  8. 77 FR 3144 - Approval and Promulgation of Air Quality Implementation Plans; Missouri; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ...; FRL-9621-1] Approval and Promulgation of Air Quality Implementation Plans; Missouri; Reasonably Available Control Technology (RACT) for the 8-Hour Ozone National Ambient Air Quality Standard (NAAQS... approve these revisions because they enhance the Missouri SIP by improving VOC emission controls...

  9. 78 FR 45112 - Approval and Promulgation of Air Quality Implementation Plans; Missouri; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Missouri; Reasonably Available Control Technology (RACT) for the 8-Hour Ozone National Ambient Air Quality Standard (NAAQS... dated May 4, 2012. The purpose of the SIP revision is to amend Missouri's regulation for the Control...

  10. 77 FR 14691 - Approval and Promulgation of Air Quality Implementation Plans; Rhode Island; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... declarations for the Plan for the 8-Hour Ozone page number following Control National Ambient Air Quality where... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Rhode Island; Reasonably Available Control Technology (RACT) for the 1997 8-Hour Ozone Standard AGENCY:...

  11. On Programming Models for Service-Level High Availability

    SciTech Connect

    Engelmann, Christian; Scott, Stephen L; Leangsuksun, Chokchai; He, X.

    2007-01-01

    This paper provides an overview of existing programming models for service-level high availability and investigates their differences, similarities, advantages, and disadvantages. Its goal is to help to improve reuse of code and to allow adaptation to quality of service requirements by using a uniform programming model description. It further aims at encouraging a discussion about these programming models and their provided quality of service, such as availability, performance, serviceability, usability, and applicability. Within this context, the presented research focuses on providing high availability for services running on head and service nodes of high-performance computing systems.

  12. SeaDataNet network services monitoring: Definition and Implementation of Service availability index

    NASA Astrophysics Data System (ADS)

    Lykiardopoulos, Angelos; Mpalopoulou, Stavroula; Vavilis, Panagiotis; Pantazi, Maria; Iona, Sissy

    2014-05-01

    SeaDataNet (SDN) is a standardized system for managing large and diverse data sets collected by the oceanographic fleets and the automatic observation systems. The SeaDataNet network is constituted of national oceanographic data centres of 35 countries, active in data collection. SeaDataNetII project's objective is to upgrade the present SeaDataNet infrastructure into an operationally robust and state-of-the-art infrastructure; therefore Network Monitoring is a step to this direction. The term Network Monitoring describes the use of system that constantly monitors a computer network for slow or failing components and that notifies the network administrator in case of outages. Network monitoring is crucial when implementing widely distributed systems over the Internet and in real-time systems as it detects malfunctions that may occur and notifies the system administrator who can immediately respond and correct the problem. In the framework of SeaDataNet II project a monitoring system was developed in order to monitor the SeaDataNet components. The core system is based on Nagios software. Some plug-ins were developed to support SeaDataNet modules. On the top of Nagios Engine a web portal was developed in order to give access to local administrators of SeaDataNet components, to view detailed logs of their own service(s). Currently the system monitors 35 SeaDataNet Download Managers, 9 SeaDataNet Services, 25 GeoSeas Download Managers and 23 UBSS Download Managers . Taking advantage of the continuous monitoring of SeaDataNet system components a total availability index will be implemented. The term availability can be defined as the ability of a functional unit to be in a state to perform a required function under given conditions at a given instant of time or over a given time interval, assuming that the required external resources are provided. Availability measures can be considered as a are very important benefit becauseT - The availability trends that can be

  13. Comprehensive evaluation and clinical implementation of commercially available Monte Carlo dose calculation algorithm.

    PubMed

    Zhang, Aizhen; Wen, Ning; Nurushev, Teamour; Burmeister, Jay; Chetty, Indrin J

    2013-03-04

    A commercial electron Monte Carlo (eMC) dose calculation algorithm has become available in Eclipse treatment planning system. The purpose of this work was to evaluate the eMC algorithm and investigate the clinical implementation of this system. The beam modeling of the eMC algorithm was performed for beam energies of 6, 9, 12, 16, and 20 MeV for a Varian Trilogy and all available applicator sizes in the Eclipse treatment planning system. The accuracy of the eMC algorithm was evaluated in a homogeneous water phantom, solid water phantoms containing lung and bone materials, and an anthropomorphic phantom. In addition, dose calculation accuracy was compared between pencil beam (PB) and eMC algorithms in the same treatment planning system for heterogeneous phantoms. The overall agreement between eMC calculations and measurements was within 3%/2 mm, while the PB algorithm had large errors (up to 25%) in predicting dose distributions in the presence of inhomogeneities such as bone and lung. The clinical implementation of the eMC algorithm was investigated by performing treatment planning for 15 patients with lesions in the head and neck, breast, chest wall, and sternum. The dose distributions were calculated using PB and eMC algorithms with no smoothing and all three levels of 3D Gaussian smoothing for comparison. Based on a routine electron beam therapy prescription method, the number of eMC calculated monitor units (MUs) was found to increase with increased 3D Gaussian smoothing levels. 3D Gaussian smoothing greatly improved the visual usability of dose distributions and produced better target coverage. Differences of calculated MUs and dose distributions between eMC and PB algorithms could be significant when oblique beam incidence, surface irregularities, and heterogeneous tissues were present in the treatment plans. In our patient cases, monitor unit differences of up to 7% were observed between PB and eMC algorithms. Monitor unit calculations were also preformed

  14. Examining Perceptions over the Effectiveness of Professional Development and Available Resources on the Common Core State Standards Implementation in Arkansas

    ERIC Educational Resources Information Center

    Sheppard, Julie Trammell

    2013-01-01

    The purpose of this qualitative case study is to examine the perceptions of teachers and curriculum specialists over the effectiveness of professional development and available resources of the Common Core State Standards (CCSS) implementation process in Arkansas. Arkansas divided the implementation process into three stages: Phase I implemented…

  15. Instrumentation Standard Architectures for Future High Availability Control Systems

    SciTech Connect

    Larsen, R.S.; /SLAC

    2005-10-13

    Architectures for next-generation modular instrumentation standards should aim to meet a requirement of High Availability, or robustness against system failure. This is particularly important for experiments both large and small mounted on production accelerators and light sources. New standards should be based on architectures that (1) are modular in both hardware and software for ease in repair and upgrade; (2) include inherent redundancy at internal module, module assembly and system levels; (3) include modern high speed serial inter-module communications with robust noise-immune protocols; and (4) include highly intelligent diagnostics and board-management subsystems that can predict impending failure and invoke evasive strategies. The simple design principles lead to fail-soft systems that can be applied to any type of electronics system, from modular instruments to large power supplies to pulsed power modulators to entire accelerator systems. The existing standards in use are briefly reviewed and compared against a new commercial standard which suggests a powerful model for future laboratory standard developments. The past successes of undertaking such projects through inter-laboratory engineering-physics collaborations will be briefly summarized.

  16. The availability of novelty sweets within high school localities.

    PubMed

    Aljawad, A; Morgan, M Z; Rees, J S; Fairchild, R

    2016-06-10

    Background Reducing sugar consumption is a primary focus of current global public health policy. Achieving 5% of total energy from free sugars will be difficult acknowledging the concentration of free sugars in sugar sweetened beverages, confectionery and as hidden sugars in many savoury items. The expansion of the novelty sweet market in the UK has significant implications for children and young adults as they contribute to dental caries, dental erosion and obesity.Objective To identify the most available types of novelty sweets within the high school fringe in Cardiff, UK and to assess their price range and where and how they were displayed in shops.Subjects and methods Shops within a ten minute walking distance around five purposively selected high schools in the Cardiff aea representing different levels of deprivation were visited. Shops in Cardiff city centre and three supermarkets were also visited to identify the most commonly available novelty sweets.Results The ten most popular novelty sweets identified in these scoping visits were (in descending order): Brain Licker, Push Pop, Juicy Drop, Lickedy Lips, Big Baby Pop, Vimto candy spray, Toxic Waste, Tango candy spray, Brain Blasterz Bitz and Mega Mouth candy spray. Novelty sweets were located on low shelves which were accessible to all age-groups in 73% (14 out of 19) of the shops. Novelty sweets were displayed in the checkout area in 37% (seven out of 19) shops. The price of the top ten novelty sweets ranged from 39p to £1.Conclusion A wide range of acidic and sugary novelty sweets were easily accessible and priced within pocket money range. Those personnel involved in delivering dental and wider health education or health promotion need to be aware of recent developments in children's confectionery. The potential effects of these novelty sweets on both general and dental health require further investigation.

  17. Implementing a High Quality Naptime Routine

    ERIC Educational Resources Information Center

    Button, Lana

    2008-01-01

    Naptime is designed to allow children to physically rest and emotionally unwind. It is a time of day where the "care" in child care really comes into play. But the reality is that naptime in a child care center is often a part of the daily schedule that children and staff both dread. This article presents some tips for planning and implementing a…

  18. 75 FR 43066 - Approval and Promulgation of Implementation Plans; New York Reasonably Available Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... Control Technology and Reasonably Available Control Measures AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is conditionally approving the reasonably available control technology..., some information is not publicly available, e.g., CBI or other information whose disclosure...

  19. 75 FR 4769 - Availability of Grant Funds and Proposed Implementation Guidelines; Withdrawal of Solicitation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Proposed Implementation Guidelines; Withdrawal of Solicitation for the Marine Aquaculture Initiative AGENCY... solicitation of applications for the NOAA Marine Aquaculture Initiative 2010, which was published in the NOAA... notice, beginning on page 3110, was a solicitation of applications for the NOAA Marine...

  20. 77 FR 14715 - Approval and Promulgation of Air Quality Implementation Plans; Rhode Island; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ...; Reasonably Available Control Technology (RACT) for the 1997 8-Hour Ozone Standard AGENCY: Environmental... available control technology (RACT) for oxides of nitrogen (NO X ) and volatile organic compounds (VOCs) set forth by the Clean Air Act (CAA) with respect to the 1997 8-hour ozone standard. The intended effect...

  1. High Molybdenum availability for evolution in a Mesoproterozoic lacustrine environment.

    PubMed

    Parnell, John; Spinks, Samuel; Andrews, Steven; Thayalan, Wanethon; Bowden, Stephen

    2015-05-19

    Trace metal data for Proterozoic marine euxinic sediments imply that the expansion of nitrogen-fixing cyanobacteria and diversification of eukaryotes were delayed while the availability of bioessential metals such as molybdenum in the ocean was limited. However, there is increasing recognition that the Mesoproterozoic evolution of nitrogen fixation and eukaryotic life may have been promoted in marginal marine and terrestrial environments, including lakes, rather than in the deep ocean. Molybdenum availability is critical to life in lakes, just as it is in the oceans. It is, therefore, important to assess molybdenum availability to the lacustrine environment in the Mesoproterozoic. Here we show that the flux of molybdenum to a Mesoproterozoic lake was 1 to 2 orders of magnitude greater than typical fluxes in the modern and ancient marine environment. Thus, there was no barrier to availability to prevent evolution in the terrestrial environment, in contrast to the nutrient-limited Mesoproterozoic oceans.

  2. High Molybdenum availability for evolution in a Mesoproterozoic lacustrine environment

    NASA Astrophysics Data System (ADS)

    Parnell, John; Spinks, Samuel; Andrews, Steven; Thayalan, Wanethon; Bowden, Stephen

    2015-05-01

    Trace metal data for Proterozoic marine euxinic sediments imply that the expansion of nitrogen-fixing cyanobacteria and diversification of eukaryotes were delayed while the availability of bioessential metals such as molybdenum in the ocean was limited. However, there is increasing recognition that the Mesoproterozoic evolution of nitrogen fixation and eukaryotic life may have been promoted in marginal marine and terrestrial environments, including lakes, rather than in the deep ocean. Molybdenum availability is critical to life in lakes, just as it is in the oceans. It is, therefore, important to assess molybdenum availability to the lacustrine environment in the Mesoproterozoic. Here we show that the flux of molybdenum to a Mesoproterozoic lake was 1 to 2 orders of magnitude greater than typical fluxes in the modern and ancient marine environment. Thus, there was no barrier to availability to prevent evolution in the terrestrial environment, in contrast to the nutrient-limited Mesoproterozoic oceans.

  3. 76 FR 66013 - Approval and Promulgation of Air Quality Implementation Plans; Missouri; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... Synthetic Organic Chemical Leaks From Synthetic Organic Chemical Manufacturing. and Polymer Manufacturing... revisions is to satisfy the RACT requirements for volatile organic compounds (VOCs) set forth by the Clean... application of control technology that is reasonably available, considering technological and...

  4. 77 FR 64787 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION... Available Control Technology Requirements for Volatile Organic Compounds AGENCY: Environmental Protection... printing and letterpress printing; flat wood paneling coatings and flexible package printing. This...

  5. 76 FR 42612 - Approval and Promulgation of Air Quality Implementation Plans; Vermont; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION... Available Control Technology (RACT) for the 1997 8- Hour Ozone Standard AGENCY: Environmental Protection... gasoline plants regulation; and new requirements for wood furniture manufacturing operations....

  6. 78 FR 5290 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION... Available Control Technology Requirements for Volatile Organic Compounds AGENCY: Environmental Protection... printing; flat wood paneling coatings; and flexible package printing. EPA is approving these revisions...

  7. 76 FR 44279 - Implementation of Section 304 of the Telecommunications Act of 1996: Commercial Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ...: Commercial Availability of Navigation Devices; Compatibility Between Cable Systems and Consumer Electronics... electronics equipment. DATES: The amendments to 47 CFR 76.1205(b)(1), 76.1205(b)(1)(i), 76.1205(b)(2),...

  8. 75 FR 27256 - Implementation of Section 304 of the Telecommunications Act of 1996: Commercial Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ...: Commercial Availability of Navigation Devices; Compatibility Between Cable Systems and Consumer Electronics... cable operators and the consumer electronics industry to establish the technical details of the... Cable and Telecommunications Association and the Consumer Electronics Association had agreed in...

  9. Engineering in High School: Implementing TMMW & TPE.

    ERIC Educational Resources Information Center

    Bordoloi, Kiron C.; Cole, Joseph D.

    1979-01-01

    The success of two engineering and technology-oriented secondary school programs is discussed. Also presented is the Man Made World and the Technology-People-Environment at two suburban high schools. (BB)

  10. 77 FR 58063 - Approval and Promulgation of Implementation Plans; Texas; Reasonably Available Control Technology...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... Organic Chemical Manufacturing Sec. 115.352-359. Industry--Polymer & Resin Manufacturing. Gasoline Tank... Reasonably Available Control Technology (RACT) requirements for Volatile Organic Compounds (VOC) and Oxides... of Air Pollution from Volatile Organic Compounds, and (3) Voluntary Mobile Emission Reduction...

  11. 78 FR 19599 - Approval and Promulgation of Implementation Plans; Texas; Reasonably Available Control Technology...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ...) as meeting certain Reasonably Available Control Technology (RACT) requirements for Volatile Organic.../Gasoline Sec. 115.352-359 Processing. Synthetic Organic Chemical Sec. 115.352-359 Manufacturing Industry- Polymer & Resin Manufacturing. Gasoline Tank Trucks & Vapor Sec. 115.211-219 and Sec. 115.234-...

  12. 78 FR 38587 - Approval and Promulgation of Air Quality Implementation Plans; Connecticut; Reasonably Available...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... From the Federal Register Online via the Government Publishing Office ] ENVIRONMENTAL PROTECTION...; Reasonably Available Control Technology for the 1997 8- Hour Ozone Standard AGENCY: Environmental Protection... electronically through www.regulations.gov or in hard copy at the Office of Ecosystem Protection,...

  13. Status Update for Implementing Best Available Technology per DOE Order 5400.5 - September 2002

    SciTech Connect

    Lewis, Michael George

    2002-09-01

    This report identifies discharges of liquid waste streams that require documentation of the Best Available Technology selection process at Bechtel BWXT Idaho, LLC, operated facilities at the Idaho National Engineering and Environmental Laboratory. The Best Available Technology selection process is conducted according to Department of Energy Order 5400.5, Chapter II (3),“Management and Control of Radioactive Materials in Liquid Discharges and Phaseout of Soil Columns” and Department of Energy guidance. Only those liquid waste streams and facilities requiring the Best Available Technology selection process are evaluated in further detail. In addition, this report will be submitted to the Department of Energy Idaho Operations Office Field Office manager for approval according to DOE Order 5400.5, Chapter II, Section 3.b.(1). Two facilities (Idaho Nuclear Technology and Engineering Center existing Percolation Ponds and Test Area North/Technical Support Facility Disposal Pond) at the Idaho National Engineering and Environmental Laboratory required documentation of the Best Available Technology selection process (Section 4). These two facilities required documentation of the Best Available Technology selection process because they discharge wastewater that may contain process-derived radionuclides to a soil column even though the average radioactivity levels are typically below drinking water maximum contaminant levels. At the request of the Department of Energy Idaho Operations Office, the 73.5-acre Central Facilities Area Sewage Treatment Plant land application site is included in Section 4 of this report to ensure the requirements of DOE Order 5400.5, Chapter II, Section 3 are met. The Central Facilities Area Sewage Treatment Plant effluent contains process-derived radionuclides from radioactive tracers used in certain analytical procedures. The radioactivity levels of these radionuclides are below maximum contaminant levels. According to Department of Energy

  14. Status Update for Implementing Best Available Technology per DOE Order 5400.5

    SciTech Connect

    Michael G. Lewis

    2003-09-01

    This report identifies discharges of liquid waste streams that require documentation of the best available technology selection process at Bechtel BWXT Idaho, LLC, operated facilities at the Idaho National Engineering and Environmental Laboratory. The best available technology selection process is conducted according to Department of Energy Order 5400.5, Chapter II (3), ''Management and Control of Radioactive Materials in Liquid Discharges and Phaseout of Soil Columns'' and Department of Energy guidance. This report evaluates only those liquid waste streams and facilities where the best available technology selection process was determined to be applicable. In addition, the Department of Energy Idaho Operations Office will submit this report to their field office manager for approval according to DOE Order 5400.5, Chapter II, Section 3.b.(1). According to Department of Energy guidance, ''If the liquid waste stream is below maximum contaminant levels, then the goals of the best available technology selection process are being met and the liquid waste stream is considered 'clean water.' However, it is necessary to document this through the best available technology selection process.'' Because liquid waste streams below drinking water maximum contaminant levels are already considered ''clean water,'' additional treatment technologies are considered unnecessary and unjustifiable on a cost-benefit basis and are not addressed in this report. Two facilities (Idaho Nuclear Technology and Engineering Center New Percolation Ponds and Test Area North/Technical Support Facility Disposal Pond) at the Idaho National Engineering and Environmental Laboratory required documentation of the best available technology selection process (Section 4). These two facilities required documentation of the best available technology selection process because they discharge wastewater that may contain process-derived radionuclides to a soil column even though the average radioactivity levels

  15. Status Update for Implementing Best Available Technology per DOE Order 5400.5 (2003)

    SciTech Connect

    Michael Lewis

    2004-09-01

    This report identifies discharges of liquid waste streams that require documentation of the best available technology selection process at Bechtel BWXT Idaho, LLC, operated facilities at the Idaho National Engineering and Environmental Laboratory. The best available technology selection process is conducted according to Department of Energy Order 5400.5, Chapter II (3), “Management and Control of Radioactive Materials in Liquid Discharges and Phaseout of Soil Columns” and Department of Energy guidance. This report evaluates only those liquid waste streams and facilities where the best available technology selection process was determined to apply. Two facilities (Idaho Nuclear Technology and Engineering Center New Percolation Ponds and Test Area North/Technical Support Facility Sewage Treatment Plant Disposal Pond) at the Idaho National Engineering and Environmental Laboratory required documentation of the best available technology selection process. These two facilities required documentation of the best available technology selection process because they discharge wastewater that may contain process-derived radionuclides to a soil column even though the average radioactivity levels are typically below drinking water maximum contaminant levels. At the request of the Department of Energy Idaho Operations Office, the 73.5-acre Central Facilities Area Sewage Treatment Plant land application site is included in this report to ensure the requirements of DOE Order 5400.5, Chapter II, Section 3 are met. The Central Facilities Area Sewage Treatment Plant effluent contains process-derived radionuclides from radioactive tracers used in certain analytical procedures. The radioactivity levels of these radionuclides are below maximum contaminant levels. The Department of Energy Idaho Operations Office will submit this report to their field office manager for approval according to DOE Order 5400.5, Chapter II, Section 3.b.(1).

  16. An Empirical Study of a Highly Available File System

    DTIC Science & Technology

    1994-02-01

    FACE[3). Now that serious use of such systems is feasi- of availability, since data can be updated in any network ble. it is appropriate to ask how well...crucial to the design of operation, allows continued read and write access to cached distributed file systems such as AFS[7] and Sprite 121. In data even...client from the network. This mechanism is especially valuable for mobile computing: a user may be isolated be- In this paper, we report on data

  17. Status Update for Implementing Best Available Technology per DOE Order 5400.5

    SciTech Connect

    Lewis, Michael George

    2001-09-01

    This report documents the Bechtel BWXT Idaho, LCC, operated facilities at the Idaho National Engineering and Environmental Laboratory that require the Best Available Technology selection process in accordance with Department of Energy Order 5400.5, Chapter II (3), “Management and Control of Radioactive Materials in Liquid Discharges.”1 This report differs from previous reports in that only those liquid waste streams and facilities requiring the Best Available Technology selection process will be evaluated in detail. In addition, this report will be submitted to the DOE-ID Field Office Manager for approval in accordance with DOE Order 5400.5, Chapter II, Section 3.b.(1). The report also identifies facilities addressed in last year’s report that do not require the Best Available Technology selection process to be completed. These facilities will not be addressed in future reports. This report reviews the following facilities: • Auxiliary Reactor Area • Idaho National Engineering and Environmental Laboratory Block Areas • Central Facilities Area • Idaho Nuclear Technology and Engineering Center • Idaho Falls Facilities • Power Burst Facility • Radioactive Waste Management Complex • Test Area North • Test Reactor Area. Three facilities (Central Facilities Area Sewage Treatment Plant, Idaho Nuclear Technology and Engineering Center Percolation Ponds and Test Area North/Technical Support Facility Disposal Pond) at the Idaho National Engineering and Environmental Laboratory required documentation of the Best Available Technology selection process. The Idaho Nuclear Technology and Engineering Center Percolation Ponds and Test Area North/Technical Support Facility Disposal Pond discharge wastewater that may contain process-derived radionuclides to a soil column with average radionuclide concentrations below drinking water MCLs. At the request of the Department of Energy Idaho Operations Office, Bechtel BWXT Idaho, LLC has included the 73.5acre

  18. Profits, Commercial Food Supplier Involvement, and School Vending Machine Snack Food Availability: Implications for Implementing the New Competitive Foods Rule

    ERIC Educational Resources Information Center

    Terry-McElrath, Yvonne M.; Hood, Nancy E.; Colabianchi, Natalie; O'Malley, Patrick M.; Johnston, Lloyd D.

    2014-01-01

    Background: The 2013-2014 school year involved preparation for implementing the new US Department of Agriculture (USDA) competitive foods nutrition standards. An awareness of associations between commercial supplier involvement, food vending practices, and food vending item availability may assist schools in preparing for the new standards.…

  19. 14 CFR 161.111 - Availability of data and comments on a restriction implemented pursuant to an agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS NOTICE AND APPROVAL OF AIRPORT NOISE AND ACCESS RESTRICTIONS Agreements § 161.111 Availability of data and comments on a restriction implemented pursuant to an agreement. The airport operator shall retain all relevant supporting data and...

  20. 14 CFR 161.111 - Availability of data and comments on a restriction implemented pursuant to an agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS NOTICE AND APPROVAL OF AIRPORT NOISE AND ACCESS RESTRICTIONS Agreements § 161.111 Availability of data and comments on a restriction implemented pursuant to an agreement. The airport operator shall retain all relevant supporting data and...

  1. Does High Educational Attainment Limit the Availability of Romantic Partners?

    ERIC Educational Resources Information Center

    Burt, Isaac; Lewis, Sally V.; Beverly, Monifa G.; Patel, Samir H.

    2010-01-01

    Research indicates that highly educated individuals endure hardships in finding suitable romantic partners. Romantic hardships affect social and emotional adjustment levels, leading to low self-efficacy in relationship decision making. To address the need for research pertaining to this topic, the authors explored the experiences of eight…

  2. 2006 Update for Implementing Best Available Technology per DOE Order 5400.5

    SciTech Connect

    Michael G. Lewis

    2007-09-01

    In accordance with Contract Data Requirements List F.19, this report addresses the Best Available Technology requirements per Department of Energy (DOE) Order 5400.5, “Radiation Protection of the Public and the Environment,” as they apply to radiological discharges to the soil for Calendar Year 2006. The report includes review of discharges for both, Battelle Energy Alliance, LLC and CH2M WG Idaho, LLC. The Best Available Technology selection process is applicable to wastewater discharges containing process derived radionuclides to surface waters, sanitary sewerages greater than five times the Derived Concentration Guideline (found in DOE Order 5400.5), and to the soil. Wastewater at the Idaho National Laboratory Site is not discharged to surface water (Big Lost River and Birch Creek) nor is it discharged to sanitary sewerages at activity levels greater than five times a Derived Concentration Guideline. Therefore, this report focuses on radiological discharges to the soil.

  3. 2005 Update for Implementing Best Available Technology per DOE Order 5400.5

    SciTech Connect

    INL

    2006-09-01

    The report addresses Best Available Technology per DOE Order 5400.5 in relation to wastewater discharges to the soil. In accordance with Contract Data Requirements List F.19, this report addresses the Best Available Technology requirements per Department of Energy (DOE) Order 5400.5, "Radiation Protection of the Public and the Environment", as they apply to radiological discharges to the soil for Calendar Year 2005. The report includes review of discharges for both, Battelle Energy Alliance, LLC and CH2M WG Idaho, LLC. The Best Available Technology selection process is applicable to wastewater discharges containing process derived radionuclides to surface waters, sanitary sewerages greater than five times the Derived Concentration Guideline (found in DOE Order 5400.5), and to the soil. Wastewater at the Idaho National Laboratory Site is not discharged to surface water (Big Lost River and Birch Creek) nor is it discharged to sanitary sewerages at activity levels greater than five times a Derived Concentration Guideline. Therefore, this report focuses on radiological discharges to the soil.

  4. Implementation of High Speed Distributed Data Acquisition System

    NASA Astrophysics Data System (ADS)

    Raju, Anju P.; Sekhar, Ambika

    2012-09-01

    This paper introduces a high speed distributed data acquisition system based on a field programmable gate array (FPGA). The aim is to develop a "distributed" data acquisition interface. The development of instruments such as personal computers and engineering workstations based on "standard" platforms is the motivation behind this effort. Using standard platforms as the controlling unit allows independence in hardware from a particular vendor and hardware platform. The distributed approach also has advantages from a functional point of view: acquisition resources become available to multiple instruments; the acquisition front-end can be physically remote from the rest of the instrument. High speed data acquisition system transmits data faster to a remote computer system through Ethernet interface. The data is acquired through 16 analog input channels. The input data commands are multiplexed and digitized and then the data is stored in 1K buffer for each input channel. The main control unit in this design is the 16 bit processor implemented in the FPGA. This 16 bit processor is used to set up and initialize the data source and the Ethernet controller, as well as control the flow of data from the memory element to the NIC. Using this processor we can initialize and control the different configuration registers in the Ethernet controller in a easy manner. Then these data packets are sending to the remote PC through the Ethernet interface. The main advantages of the using FPGA as standard platform are its flexibility, low power consumption, short design duration, fast time to market, programmability and high density. The main advantages of using Ethernet controller AX88796 over others are its non PCI interface, the presence of embedded SRAM where transmit and reception buffers are located and high-performance SRAM-like interface. The paper introduces the implementation of the distributed data acquisition using FPGA by VHDL. The main advantages of this system are high

  5. High sensitivity of northeastern broadleaf forest trees to water availability

    NASA Astrophysics Data System (ADS)

    Levesque, M.; Pederson, N.; Andreu-Hayles, L.

    2015-12-01

    Temperate deciduous forests of eastern US provide goods and services to millions of people and play a vital role in the terrestrial carbon and hydrological cycles. However, ongoing climate change and increased in CO2 concentration in the atmosphere (ca) are expected to alter growth and gas exchange of trees, and ultimately forest productivity. Still, the magnitude of these effects is unclear. A better comprehension of the species-specific responses to environmental changes will better inform models and managers on the vulnerability and resiliency of these forests. Tree-ring analysis was combined with δ¹³C and δ18O measurements to investigate growth and physiological responses of red oak (Quercus rubra L.) and tulip poplar (Liriodendron tulipifera L.) in northeastern US to changes in water availability and ca for the period 1950-2014. We found very strong correlations between summer climatic water balance (June-August) and isotopic tree-ring series for δ¹³C (r = -0.65 and -0.73), and δ18O (r = -0.59 and -0.70), for red oak and tulip poplar, respectively. In contrast, tree-ring width was less sensitive to summer water availability (r = 0.33-0.39). Prior to the mid 1980s, low water availability resulted in low stomatal conductance, photosynthesis, and growth. Since that period, pluvial conditions occurring in northeastern US have increased stomatal conductance, carbon uptake, and growth of both species. These findings demonstrate that broadleaf trees in this region could be more sensitive to drought than expected. This appears especially true since much of the calibration period looks wet in a multi-centennial perspective. Further, stronger spatial correlations were found between climate data with tree-ring isotopes than with tree-ring width and the geographical area of the observed δ18O-precipitation response (i.e. the area over which correlations are > 0.5) covers most of the northeastern US. Given the good fit between the isotopic time series and water

  6. High nitrogen availability reduces polyphenol content in Sphagnum peat.

    PubMed

    Bragazza, Luca; Freeman, Chris

    2007-05-15

    Peat mosses of the genus Sphagnum constitute the bulk of living and dead biomass in bogs. These plants contain peculiar polyphenols which hamper litter peat decomposition through their inhibitory activity on microbial breakdown. In the light of the increasing availability of biologically active nitrogen in natural ecosystems, litter derived from Sphagnum mosses is an ideal substrate to test the potential effects of increased atmospheric nitrogen deposition on polyphenol content in litter peat. To this aim, we measured total nitrogen and soluble polyphenol concentration in Sphagnum litter peat collected in 11 European bogs under a chronic gradient of atmospheric nitrogen deposition. Our results demonstrate that increasing nitrogen concentration in Sphagnum litter, as a consequence of increased exogenous nitrogen availability, is accompanied by a decreasing concentration of polyphenols. This inverse relationship is consistent with reports that in Sphagnum mosses, polyphenol and protein biosynthesis compete for the same precursor. Our observation of modified Sphagnum litter chemistry under chronic nitrogen eutrophication has implications in the context of the global carbon balance, because a lower content of decay-inhibiting polyphenols would accelerate litter peat decomposition.

  7. Availability of high-pressure safety injection system in PWRs

    SciTech Connect

    Sun, Y.H.; Fresco, A.; Papazoglou, I.A.

    1983-01-01

    This paper presents an evaluation of the impact of typical variations in configuration of the design of the High Pressure Injection (HPSI) System on system unavailability. The HPSI systems in seventeen nuclear power plants were reviewed for variations in design, systems operation, testing and maintenance policies, and possible sources for common cause failures. The power plants reviewed include PWRs with two, three and four loop Reactor Coolant Systems and cover all three PWR vendors. As a result of this effort, the following five representative configurations (along with some variations) were identified and their unavailability to initiate injection was estimated.

  8. Implementation of high throughput experimentation techniques for kinetic reaction testing.

    PubMed

    Nagy, Anton J

    2012-02-01

    Successful implementation of High throughput Experimentation (EE) tools has resulted in their increased acceptance as essential tools in chemical, petrochemical and polymer R&D laboratories. This article provides a number of concrete examples of EE systems, which have been designed and successfully implemented in studies, which focus on deriving reaction kinetic data. The implementation of high throughput EE tools for performing kinetic studies of both catalytic and non-catalytic systems results in a significantly faster acquisition of high-quality kinetic modeling data, required to quantitatively predict the behavior of complex, multistep reactions.

  9. Availability of High School Extracurricular Sports Programs and High-Risk Behaviors

    ERIC Educational Resources Information Center

    Cohen, Deborah A.; Taylor, Stephanie L.; Zonta, Michela; Vestal, Katherine D.; Schuster, Mark A.

    2007-01-01

    Background: The Surgeon General has called for an expansion of school-based extracurricular sports programs to address the obesity epidemic. However, little is known about the availability of and participation in high school extracurricular sports and how participation in these sports is related to high-risk behaviors. Methods: We surveyed Los…

  10. Implementation of weather stations at Ghanaian high schools

    NASA Astrophysics Data System (ADS)

    Pieron, M.

    2012-04-01

    The Trans-African Hydro-Meteorological Observatory (www.tahmo.org) is an initiative that aims to develop a dense weather observation network in Sub-Sahara Africa. The ambition is to have 20.000 low-cost innovative weather stations in place in 2015. An increased amount of weather data is locally required to provide stakeholders that are dependent on the weather, such as farmers and fishermen, with accurate forecasts. As a first proof of concept, showing that sensors can be built at costs lower than commercially available, a disdrometer was developed. In parallel with the design of the measurement instruments, a high school curriculum is developed that covers environmental sciences. In order to find out which requirements the TAHMO weather station and accompanying educational materials should meet for optimal use at Junior High Schools research was done at Ghanaian schools. Useful insights regarding the future African context of the weather station and requirements for an implementation strategy were obtained during workshops with teachers and students, visits to WMO observatories and case studies regarding use of educational materials. The poster presents the conclusions of this research, which is part of the bigger TAHMO framework.

  11. Performing Arts Program, Badger High School: Justification, Proposal, Implementation, Stage One Implementation.

    ERIC Educational Resources Information Center

    Holmes, Dan

    This document presents a justification, proposal, and implementation plan for a comprehensive theatre arts program at Badger High School, Lake Geneva, Wisconsin that would offer a full schedule of amateur and professional arts programs involving the students and the community. The brief Justification section notes that every elementary and…

  12. Implementation of SWPBIS in High School: Why Is It Different?

    ERIC Educational Resources Information Center

    Flannery, K. Brigid; Kato, Mimi McGrath

    2017-01-01

    Schoolwide Positive Behavioral Intervention and Supports (SWPBIS) is a framework for establishing a schoolwide positive social culture with a continuum of behavior supports and an effective learning environment for all students. This framework was initially implemented in elementary and middle schools and more recently in high schools. Coaches for…

  13. Technology's Achilles Heel: Achieving High-Quality Implementation

    ERIC Educational Resources Information Center

    Hall, Gene E.

    2010-01-01

    An inherent characteristic of technology education is the continual development of new technologies and creating innovative applications of already existing technologies. As exciting as these innovations can be, technology educators and school staffs are frequently challenged to accomplish high levels of implementation. The metaphor of the…

  14. Implementing Effective Schools Research: The Audit Process High School Observations.

    ERIC Educational Resources Information Center

    Brubaker, Hal; Partin, Ron

    During May of 1985, an external audit team was engaged by the Lorain (Ohio) City Schools to assess implementation of the seven correlates of an effective school. The correlates, developed by the Ohio State Department of Education, included: (1) a sense of mission; (2) strong building leadership; (3) high expectations for all students and staff;…

  15. Development of high-availability ATCA/PCIe data acquisition instrumentation

    SciTech Connect

    Correia, Miguel; Sousa, Jorge; Batista, Antonio J.N.; Combo, Alvaro; Santos, Bruno; Rodrigues, Antonio P.; Carvalho, Paulo F.; Goncalves, Bruno; Correia, Carlos M.B.A.

    2015-07-01

    Latest Fusion energy experiments envision a quasi-continuous operation regime. In consequence, the largest experimental devices, currently in development, specify high-availability (HA) requirements for the whole plant infrastructure. HA features enable the whole facility to perform seamlessly in the case of failure of any of its components, coping with the increasing duration of plasma discharges (steady-state) and assuring safety of equipment, people, environment and investment. IPFN developed a control and data acquisition system, aiming for fast control of advanced Fusion devices, which is thus required to provide such HA features. The system is based on in-house developed Advanced Telecommunication Computing Architecture (ATCA) instrumentation modules - IO blades and data switch blades, establishing a PCIe network on the ATCA shelf's back-plane. The data switch communicates to an external host computer through a PCIe data network. At the hardware management level, the system architecture takes advantage of ATCA native redundancy and hot swap specifications to implement fail-over substitution of IO or data switch blades. A redundant host scheme is also supported by the ATCA/PCIe platform. At the software level, PCIe provides implementation of hot plug services, which translate the hardware changes to the corresponding software/operating system devices. The paper presents how the ATCA and PCIe based system can be setup to perform with the desired degree of HA, thus being suitable for advanced Fusion control and data acquisition systems. (authors)

  16. Cooperative implementation of a high temperature acoustic sensor

    NASA Technical Reports Server (NTRS)

    Baldini, S. E.; Nowakowski, Edward; Smith, Herbert G.; Friebele, E. J.; Putnam, Martin A.; Rogowski, Robert; Melvin, Leland D.; Claus, Richard O.; Tran, Tuan; Holben, Milford S., Jr.

    1991-01-01

    The current status and results of a cooperative program aimed at the implementation of a high-temperature acoustic/strain sensor onto metallic structures are reported. The sensor systems that are to be implemented under this program will measure thermal expansion, maneuver loads, aircraft buffet, sonic fatigue, and acoustic emissions in environments that approach 1800 F. The discussion covers fiber development, fabrication of an extrinsic Fabry-Perot interferometer acoustic sensor, sensor mounting/integration, and results of an evaluation of the sensor capabilities.

  17. High-resolution subgrid models: background, grid generation, and implementation

    NASA Astrophysics Data System (ADS)

    Sehili, Aissa; Lang, Günther; Lippert, Christoph

    2014-04-01

    The basic idea of subgrid models is the use of available high-resolution bathymetric data at subgrid level in computations that are performed on relatively coarse grids allowing large time steps. For that purpose, an algorithm that correctly represents the precise mass balance in regions where wetting and drying occur was derived by Casulli (Int J Numer Method Fluids 60:391-408, 2009) and Casulli and Stelling (Int J Numer Method Fluids 67:441-449, 2010). Computational grid cells are permitted to be wet, partially wet, or dry, and no drying threshold is needed. Based on the subgrid technique, practical applications involving various scenarios were implemented including an operational forecast model for water level, salinity, and temperature of the Elbe Estuary in Germany. The grid generation procedure allows a detailed boundary fitting at subgrid level. The computational grid is made of flow-aligned quadrilaterals including few triangles where necessary. User-defined grid subdivision at subgrid level allows a correct representation of the volume up to measurement accuracy. Bottom friction requires a particular treatment. Based on the conveyance approach, an appropriate empirical correction was worked out. The aforementioned features make the subgrid technique very efficient, robust, and accurate. Comparison of predicted water levels with the comparatively highly resolved classical unstructured grid model shows very good agreement. The speedup in computational performance due to the use of the subgrid technique is about a factor of 20. A typical daily forecast can be carried out in less than 10 min on a standard PC-like hardware. The subgrid technique is therefore a promising framework to perform accurate temporal and spatial large-scale simulations of coastal and estuarine flow and transport processes at low computational cost.

  18. High-Performance CCSDS Encapsulation Service Implementation in FPGA

    NASA Technical Reports Server (NTRS)

    Clare, Loren P.; Torgerson, Jordan L.; Pang, Jackson

    2010-01-01

    The Consultative Committee for Space Data Systems (CCSDS) Encapsulation Service is a convergence layer between lower-layer space data link framing protocols, such as CCSDS Advanced Orbiting System (AOS), and higher-layer networking protocols, such as CFDP (CCSDS File Delivery Protocol) and Internet Protocol Extension (IPE). CCSDS Encapsulation Service is considered part of the data link layer. The CCSDS AOS implementation is described in the preceding article. Recent advancement in RF modem technology has allowed multi-megabit transmission over space links. With this increase in data rate, the CCSDS Encapsulation Service needs to be optimized to both reduce energy consumption and operate at a high rate. CCSDS Encapsulation Service has been implemented as an intellectual property core so that the aforementioned problems are solved by way of operating the CCSDS Encapsulation Service inside an FPGA. The CCSDS En capsula tion Service in FPGA implementation consists of both packetizing and de-packetizing features

  19. JOSHUA: Symmetric Active/Active Replication for Highly Available HPC Job and Resource Management

    SciTech Connect

    Uhlemann, Kai; Engelmann, Christian; Scott, Steven L

    2006-01-01

    Most of today's HPC systems employ a single head node for control, which represents a single point of failure as it interrupts an entire HPC system upon failure. Furthermore, it is also a single point of control as it disables an entire HPC system until repair. One of the most important HPC system service running on the head node is the job and resource management. If it goes down, all currently running jobs loose the service they report back to. They have to be restarted once the head node is up and running again. With this paper, we present a generic approach for providing symmetric active/active replication for highly available HPC job and resource management. The JOSHUA solution provides a virtually synchronous environment for continuous availability without any interruption of service and without any loss of state. Replication is performed externally via the PBS service interface without the need to modify any service code. Test results as well as a reliability analysis of our proof-of-concept prototype implementation show that continuous availability can be provided by JOSHUA with an acceptable performance trade-off.

  20. High performance computing and communications: FY 1996 implementation plan

    SciTech Connect

    1995-05-16

    The High Performance Computing and Communications (HPCC) Program was formally authorized by passage of the High Performance Computing Act of 1991, signed on December 9, 1991. Twelve federal agencies, in collaboration with scientists and managers from US industry, universities, and research laboratories, have developed the Program to meet the challenges of advancing computing and associated communications technologies and practices. This plan provides a detailed description of the agencies` HPCC implementation plans for FY 1995 and FY 1996. This Implementation Plan contains three additional sections. Section 3 provides an overview of the HPCC Program definition and organization. Section 4 contains a breakdown of the five major components of the HPCC Program, with an emphasis on the overall directions and milestones planned for each one. Section 5 provides a detailed look at HPCC Program activities within each agency.

  1. Highly parallel consistent labeling algorithm suitable for optoelectronic implementation.

    PubMed

    Marsden, G C; Kiamilev, F; Esener, S; Lee, S H

    1991-01-10

    Constraint satisfaction problems require a search through a large set of possibilities. Consistent labeling is a method by which search spaces can be drastically reduced. We present a highly parallel consistent labeling algorithm, which achieves strong k-consistency for any value k and which can include higher-order constraints. The algorithm uses vector outer product, matrix summation, and matrix intersection operations. These operations require local computation with global communication and, therefore, are well suited to a optoelectronic implementation.

  2. Developing and implementing a high precision setup system

    NASA Astrophysics Data System (ADS)

    Peng, Lee-Cheng

    The demand for high-precision radiotherapy (HPRT) was first implemented in stereotactic radiosurgery using a rigid, invasive stereotactic head frame. Fractionated stereotactic radiotherapy (SRT) with a frameless device was developed along a growing interest in sophisticated treatment with a tight margin and high-dose gradient. This dissertation establishes the complete management for HPRT in the process of frameless SRT, including image-guided localization, immobilization, and dose evaluation. The most ideal and precise positioning system can allow for ease of relocation, real-time patient movement assessment, high accuracy, and no additional dose in daily use. A new image-guided stereotactic positioning system (IGSPS), the Align RT3C 3D surface camera system (ART, VisionRT), which combines 3D surface images and uses a real-time tracking technique, was developed to ensure accurate positioning at the first place. The uncertainties of current optical tracking system, which causes patient discomfort due to additional bite plates using the dental impression technique and external markers, are found. The accuracy and feasibility of ART is validated by comparisons with the optical tracking and cone-beam computed tomography (CBCT) systems. Additionally, an effective daily quality assurance (QA) program for the linear accelerator and multiple IGSPSs is the most important factor to ensure system performance in daily use. Currently, systematic errors from the phantom variety and long measurement time caused by switching phantoms were discovered. We investigated the use of a commercially available daily QA device to improve the efficiency and thoroughness. Reasonable action level has been established by considering dosimetric relevance and clinic flow. As for intricate treatments, the effect of dose deviation caused by setup errors remains uncertain on tumor coverage and toxicity on OARs. The lack of adequate dosimetric simulations based on the true treatment coordinates from

  3. High performance computing and communications: FY 1995 implementation plan

    SciTech Connect

    1994-04-01

    The High Performance Computing and Communications (HPCC) Program was formally established following passage of the High Performance Computing Act of 1991 signed on December 9, 1991. Ten federal agencies in collaboration with scientists and managers from US industry, universities, and laboratories have developed the HPCC Program to meet the challenges of advancing computing and associated communications technologies and practices. This plan provides a detailed description of the agencies` HPCC implementation plans for FY 1994 and FY 1995. This Implementation Plan contains three additional sections. Section 3 provides an overview of the HPCC Program definition and organization. Section 4 contains a breakdown of the five major components of the HPCC Program, with an emphasis on the overall directions and milestones planned for each one. Section 5 provides a detailed look at HPCC Program activities within each agency. Although the Department of Education is an official HPCC agency, its current funding and reporting of crosscut activities goes through the Committee on Education and Health Resources, not the HPCC Program. For this reason the Implementation Plan covers nine HPCC agencies.

  4. Implementation of Industrial Work Practice management at vocational high school

    NASA Astrophysics Data System (ADS)

    Widodo, Joko; Samsudi, Sunyoto

    2017-03-01

    The purpose of this study was to develop a management model of entrepreneurship-based Industrial Work Practice (Prakerin) at Vocational High School. This research was planned for three years under Research and Development design. The respondents were public and private Vocational High Schools in Semarang, Salatiga and District of Demak, Central Java, Indonesia. Data were collected through interviews, questionnaires, observation, and documentation. The data were analyzed qualitatively and quantitatively. Preliminary study shows that the implementation of Industrial Work Practice at Vocational High School, which has been carried out, was only to prepare the graduates to become an employee of the industry instead of entrepreneur. Further study is needed to develop a management model of entrepreneurship-based Industrial Work Practice at Vocational High School.

  5. High Performance Storage System Scalability: Architecture, Implementation, and Experience

    SciTech Connect

    Watson, R W

    2005-01-05

    The High Performance Storage System (HPSS) provides scalable hierarchical storage management (HSM), archive, and file system services. Its design, implementation and current dominant use are focused on HSM and archive services. It is also a general-purpose, global, shared, parallel file system, potentially useful in other application domains. When HPSS design and implementation began over a decade ago, scientific computing power and storage capabilities at a site, such as a DOE national laboratory, was measured in a few 10s of gigaops, data archived in HSMs in a few 10s of terabytes at most, data throughput rates to an HSM in a few megabytes/s, and daily throughput with the HSM in a few gigabytes/day. At that time, the DOE national laboratories and IBM HPSS design team recognized that we were headed for a data storage explosion driven by computing power rising to teraops/petaops requiring data stored in HSMs to rise to petabytes and beyond, data transfer rates with the HSM to rise to gigabytes/s and higher, and daily throughput with a HSM in 10s of terabytes/day. This paper discusses HPSS architectural, implementation and deployment experiences that contributed to its success in meeting the above orders of magnitude scaling targets. We also discuss areas that need additional attention as we continue significant scaling into the future.

  6. High-Performance CCSDS AOS Protocol Implementation in FPGA

    NASA Technical Reports Server (NTRS)

    Clare, Loren P.; Torgerson, Jordan L.; Pang, Jackson

    2010-01-01

    The Consultative Committee for Space Data Systems (CCSDS) Advanced Orbiting Systems (AOS) space data link protocol provides a framing layer between channel coding such as LDPC (low-density parity-check) and higher-layer link multiplexing protocols such as CCSDS Encapsulation Service, which is described in the following article. Recent advancement in RF modem technology has allowed multi-megabit transmission over space links. With this increase in data rate, the CCSDS AOS protocol implementation needs to be optimized to both reduce energy consumption and operate at a high rate.

  7. Systems and Methods for Implementing High-Temperature Tolerant Supercapacitors

    NASA Technical Reports Server (NTRS)

    Brandon, Erik J. (Inventor); West, William C. (Inventor); Bugga, Ratnakumar V. (Inventor)

    2016-01-01

    Systems and methods in accordance with embodiments of the invention implement high-temperature tolerant supercapacitors. In one embodiment, a high-temperature tolerant super capacitor includes a first electrode that is thermally stable between at least approximately 80C and approximately 300C; a second electrode that is thermally stable between at least approximately 80C and approximately 300C; an ionically conductive separator that is thermally stable between at least approximately 80C and 300C; an electrolyte that is thermally stable between approximately at least 80C and approximately 300C; where the first electrode and second electrode are separated by the separator such that the first electrode and second electrode are not in physical contact; and where each of the first electrode and second electrode is at least partially immersed in the electrolyte solution.

  8. Implementation

    EPA Pesticide Factsheets

    Describes elements for the set of activities to ensure that control strategies are put into effect and that air quality goals and standards are fulfilled, permitting programs, and additional resources related to implementation under the Clean Air Act.

  9. Design and implementation of spaceborne high resolution infrared touch screen

    NASA Astrophysics Data System (ADS)

    Li, Tai-guo; Li, Wen-xin; Dong, Yi-peng; Ma, Wen; Xia, Jia-gao

    2015-10-01

    For the consideration of the special application environment of the electronic products used in aerospace and to further more improve the human-computer interaction of the manned aerospace area. The research is based on the design and implementation way of the high resolution spaceborne infrared touch screen on the basis of FPGA and DSP frame structure. Beside the introduction of the whole structure for the high resolution spaceborne infrared touch screen system, this essay also gives the detail information about design of hardware for the high resolution spaceborne infrared touch screen system, FPGA design, GUI design and DSP algorithm design based on Lagrange interpolation. What is more, the easy makes a comprehensive research of the reliability design for the high resolution spaceborne infrared touch screen for the special purpose of it. Besides, the system test is done after installation of spaceborne infrared touch screen. The test result shows that the system is simple and reliable enough, which has a stable running environment and high resolution, which certainly can meet the special requirement of the manned aerospace instrument products.

  10. Design and implementation of a high performance network security processor

    NASA Astrophysics Data System (ADS)

    Wang, Haixin; Bai, Guoqiang; Chen, Hongyi

    2010-03-01

    The last few years have seen many significant progresses in the field of application-specific processors. One example is network security processors (NSPs) that perform various cryptographic operations specified by network security protocols and help to offload the computation intensive burdens from network processors (NPs). This article presents a high performance NSP system architecture implementation intended for both internet protocol security (IPSec) and secure socket layer (SSL) protocol acceleration, which are widely employed in virtual private network (VPN) and e-commerce applications. The efficient dual one-way pipelined data transfer skeleton and optimised integration scheme of the heterogenous parallel crypto engine arrays lead to a Gbps rate NSP, which is programmable with domain specific descriptor-based instructions. The descriptor-based control flow fragments large data packets and distributes them to the crypto engine arrays, which fully utilises the parallel computation resources and improves the overall system data throughput. A prototyping platform for this NSP design is implemented with a Xilinx XC3S5000 based FPGA chip set. Results show that the design gives a peak throughput for the IPSec ESP tunnel mode of 2.85 Gbps with over 2100 full SSL handshakes per second at a clock rate of 95 MHz.

  11. Highly parallel implementation of non-adiabatic Ehrenfest molecular dynamics

    NASA Astrophysics Data System (ADS)

    Kanai, Yosuke; Schleife, Andre; Draeger, Erik; Anisimov, Victor; Correa, Alfredo

    2014-03-01

    While the adiabatic Born-Oppenheimer approximation tremendously lowers computational effort, many questions in modern physics, chemistry, and materials science require an explicit description of coupled non-adiabatic electron-ion dynamics. Electronic stopping, i.e. the energy transfer of a fast projectile atom to the electronic system of the target material, is a notorious example. We recently implemented real-time time-dependent density functional theory based on the plane-wave pseudopotential formalism in the Qbox/qb@ll codes. We demonstrate that explicit integration using a fourth-order Runge-Kutta scheme is very suitable for modern highly parallelized supercomputers. Applying the new implementation to systems with hundreds of atoms and thousands of electrons, we achieved excellent performance and scalability on a large number of nodes both on the BlueGene based ``Sequoia'' system at LLNL as well as the Cray architecture of ``Blue Waters'' at NCSA. As an example, we discuss our work on computing the electronic stopping power of aluminum and gold for hydrogen projectiles, showing an excellent agreement with experiment. These first-principles calculations allow us to gain important insight into the the fundamental physics of electronic stopping.

  12. A Very High Order, Adaptable MESA Implementation for Aeroacoustic Computations

    NASA Technical Reports Server (NTRS)

    Dydson, Roger W.; Goodrich, John W.

    2000-01-01

    Since computational efficiency and wave resolution scale with accuracy, the ideal would be infinitely high accuracy for problems with widely varying wavelength scales. Currently, many of the computational aeroacoustics methods are limited to 4th order accurate Runge-Kutta methods in time which limits their resolution and efficiency. However, a new procedure for implementing the Modified Expansion Solution Approximation (MESA) schemes, based upon Hermitian divided differences, is presented which extends the effective accuracy of the MESA schemes to 57th order in space and time when using 128 bit floating point precision. This new approach has the advantages of reducing round-off error, being easy to program. and is more computationally efficient when compared to previous approaches. Its accuracy is limited only by the floating point hardware. The advantages of this new approach are demonstrated by solving the linearized Euler equations in an open bi-periodic domain. A 500th order MESA scheme can now be created in seconds, making these schemes ideally suited for the next generation of high performance 256-bit (double quadruple) or higher precision computers. This ease of creation makes it possible to adapt the algorithm to the mesh in time instead of its converse: this is ideal for resolving varying wavelength scales which occur in noise generation simulations. And finally, the sources of round-off error which effect the very high order methods are examined and remedies provided that effectively increase the accuracy of the MESA schemes while using current computer technology.

  13. Assessing a parsimonious eco-hydrological model implementation to an Aleppo pine semiarid forest through available remote sensing data

    NASA Astrophysics Data System (ADS)

    Medici, C.; Pasquato, M.; Frances, F.

    2013-12-01

    Arid and semi-arid climates cover a large portion of Earth's terrestrial surface and most of the ecosystems under these conditions represent hot spots in terms of Global Change consequences. In fact, the ecosystems are controlled by water availability, inducing a tight interconnection between the hydrological cycle and the vegetation dynamics. For this reason, it is essential to model these two systems, vegetational and hydrological, concurrently. However, frequently, in operational applications the available information is quite limited. Therefore parsimonious models together with available satellite information can be valuable tools to predict the vegetation dynamic. In this work, a parsimonious dynamic vegetation model is applied to a semi-arid Aleppo Pine forest area in the south-east of Spain. The model simulates biomass increase as related to the absorbed photosynthetically active radiation (APAR) through the light use efficiency (LUE). The model is then tested against several available products offered by MODIS instruments flying onboard the Terra and Aqua satellite. The satellite information used in this study is the following: the Normalized Difference Vegetation Index (NDVI) and the Enhanced Vegetation Index (EVI), both included in the products MOD13Q1 and MYD13Q1 and provided every 16 days at 250-meters spatial resolution; the Leaf Area Index (LAI), included in the products MOD15A2 and MYD15A2 and provided every 8 days at 1000-meters spatial resolution; the actual Evapotranspiration (ET), included in the MOD16A2 product and provided every 8 days at 1000-meters spatial resolution. These satellite data were analyzed for the period 2000 - 2011 over the study area, averaging the spatial distributed data to obtain the evolution through time. All four products showed a marked seasonal quasi-sinusoidal behavior, but differences between them were noticed regarding the timing of peaks. NDVI showed a strong dependence on soil moisture and leaf water content

  14. Implementation of focusing and redirecting light through highly scattering media

    NASA Astrophysics Data System (ADS)

    Coyotl-Ocelotl, B.; Porras-Aguilar, R.; Ramos-Garcia, R.; Ramirez-San-Juan, J. C.

    2015-08-01

    Optical imaging through highly scattering media such as biological tissue is limited by light scattering. Recently, it has been shown that wavefront shaping is a powerful tool to overcome this problem. In this work, wavefront shaping using spatial light modulators is used to compensate static scattering media (piece of translucent tape) to allow focusing of different intensity distributions. Light propagation is engineered into a specific region of interest. For this purpose, a sequential phase shape algorithm was implemented experimentally. This algorithm is used to encode a phase distribution on an incident beam to pre-compensate phase distortions acquired by the beam after propagating through the tape. The sequential algorithm combined with a spatial light modulator is used to synthesize a phase distribution required for redirecting light using wavefront shaping. The scattered light was re-directed at the detector plane, in order to be: i) focused at a single pixel, ii) at squared regions of 3×3 and 5×5 pixeles and iii) a line pattern of 41 pixels of the camera. Furthermore, the region of interest was placed outside the central area of the camera opening the possibility of image formation.

  15. 77 FR 18963 - Energy Conservation Program: Public Meeting and Availability of the Framework Document for High...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... of the Framework Document for High-Intensity Discharge Lamps AGENCY: Office of Energy Efficiency and...) Lamps. The comment period is extended to April 12, 2012. DATES: The comment period for the HID Lamps... availability of framework document for high-intensity discharge (HID) lamps, initiating the rulemaking and...

  16. High nutrient availability reduces the diversity and stability of the equine caecal microbiota

    PubMed Central

    Hansen, Naja C. K.; Avershina, Ekaterina; Mydland, Liv T.; Næsset, Jon A.; Austbø, Dag; Moen, Birgitte; Måge, Ingrid; Rudi, Knut

    2015-01-01

    Background It is well known that nutrient availability can alter the gut microbiota composition, while the effect on diversity and temporal stability remains largely unknown. Methods Here we address the equine caecal microbiota temporal stability, diversity, and functionality in response to diets with different levels of nutrient availability. Hay (low and slower nutrient availability) versus a mixture of hay and whole oats (high and more rapid nutrient availability) were used as experimental diets. Results We found major effects on the microbiota despite that the caecal pH was far from sub-clinical acidosis. We found that the low nutrient availability diet was associated with a higher level of both diversity and temporal stability of the caecal microbiota than the high nutrient availability diet. These observations concur with general ecological theories, suggesting a stabilising effect of biological diversity and that high nutrient availability has a destabilising effect through reduced diversity. Conclusion Nutrient availability does not only change the composition but also the ecology of the caecal microbiota. PMID:26246403

  17. SU-E-T-492: Implementing a Method for Brain Irradiation in Rats Utilizing a Commercially Available Radiosurgery Irradiator

    SciTech Connect

    Cates, J; Drzymala, R

    2014-06-01

    Purpose: The purpose of the study was to implement a method for accurate rat brain irradiation using the Gamma Knife Perfexion unit. The system needed to be repeatable, efficient, and dosimetrically and spatially accurate. Methods: A platform (“rat holder”) was made such that it is attachable to the Leskell Gamma Knife G Frame. The rat holder utilizes two ear bars contacting bony anatomy and a front tooth bar to secure the rat. The rat holder fits inside of the Leskell localizer box, which utilizes fiducial markers to register with the GammaPlan planning system. This method allows for accurate, repeatable setup.A cylindrical phantom was made so that film can be placed axially in the phantom. We then acquired CT image sets of the rat holder and localizer box with both a rat and the phantom. Three treatment plans were created: a plan on the rat CT dataset, a phantom plan with the same prescription dose as the rat plan, and a phantom plan with the same delivery time as the rat plan. Results: Film analysis from the phantom showed that our setup is spatially accurate and repeatable. It is also dosimetrically accurate, with an difference between predicted and measured dose of 2.9%. Film analysis with prescription dose equal between rat and phantom plans showed a difference of 3.8%, showing that our phantom is a good representation of the rat for dosimetry purposes, allowing for +/- 3mm diameter variation. Film analysis with treatment time equal showed an error of 2.6%, which means we can deliver a prescription dose within 3% accuracy. Conclusion: Our method for irradiation of rat brain has been shown to be repeatable, efficient, and accurate, both dosimetrically and spatially. We can treat a large number of rats efficiently while delivering prescription doses within 3% at millimeter level accuracy.

  18. What Constitutes High-Quality Implementation of SEL Programs? A Latent Class Analysis of Second Step® Implementation.

    PubMed

    Low, Sabina; Smolkowski, Keith; Cook, Clay

    2016-11-01

    With the increased number of schools adopting social-emotional learning (SEL) programming, there is increased emphasis on the role of implementation in obtaining desired outcomes. Despite this, the current knowledge of the active ingredients of SEL programming is lacking, and there is a need to move from a focus on "whether" implementation matters to "what" aspects of implementation matter. To address this gap, the current study utilizes a latent class approach with data from year 1 of a randomized controlled trial of Second Step® (61 schools, 321 teachers, over 7300 students). Latent classes of implementation were identified, then used to predict student outcomes. Teachers reported on multiple dimensions of implementation (adherence, dosage, competency), as well as student outcomes. Observational data were also used to assess classroom behavior (academic engagement and disruptive behavior). Results suggest that a three-class model fits the data best, labeled as high-quality, low-engagement, and low-adherence classes. Only the low-engagement class showed significant associations with poorer outcomes, when compared to the high-quality class (not the low-adherence class). Findings are discussed in terms of implications for program development and implementation science more broadly.

  19. Development of a Brief Pre-Implementation Screening Tool to Identify Teachers Who Are at Risk for Not Implementing Intervention Curriculum and High-Implementing Teachers.

    PubMed

    Wang, Bo; Stanton, Bonita; Lunn, Sonja; Patel, Pooja; Koci, Veronica; Deveaux, Lynette

    2017-02-01

    Few questionnaires have been developed to screen for potentially poor implementers of school-based interventions. This study combines teacher characteristics, perceptions, and teaching/training experiences to develop a short screening tool that can identify potential "low-performing" or "high-performing" teachers pre-implementation. Data were gathered from 208 teachers and 4,411 students who participated in the national implementation of an evidence-based HIV intervention in The Bahamas. Sensitivity and specificity were evaluated for the detection of "low-performing" and "high-performing" teachers. The validity of the screening tool was assessed using receiver operating characteristics analysis. The School Pre-implementation Screening Tool consists of seven predictive factors: duration as teacher, working site, attendance at training workshops, training in interactive teaching, perceived importance of the intervention, comfort in teaching the curriculum, and program priority. The sensitivity and specificity were 74% and 57% in identifying "low-performing" teachers and 81% and 65% with "high-performing" teachers. The screening tool demonstrated an acceptable/good validity (area under the receiver operating characteristics curve was 0.68 for "low-performing teachers" and 0.78 for "high-performing" teachers). Our brief screening tool can facilitate teacher training and recruitment of engaged teachers in implementation of school-based interventions.

  20. Building highly available control system applications with Advanced Telecom Computing Architecture and open standards

    NASA Astrophysics Data System (ADS)

    Kazakov, Artem; Furukawa, Kazuro

    2010-11-01

    Requirements for modern and future control systems for large projects like International Linear Collider demand high availability for control system components. Recently telecom industry came up with a great open hardware specification - Advanced Telecom Computing Architecture (ATCA). This specification is aimed for better reliability, availability and serviceability. Since its first market appearance in 2004, ATCA platform has shown tremendous growth and proved to be stable and well represented by a number of vendors. ATCA is an industry standard for highly available systems. On the other hand Service Availability Forum, a consortium of leading communications and computing companies, describes interaction between hardware and software. SAF defines a set of specifications such as Hardware Platform Interface, Application Interface Specification. SAF specifications provide extensive description of highly available systems, services and their interfaces. Originally aimed for telecom applications, these specifications can be used for accelerator controls software as well. This study describes benefits of using these specifications and their possible adoption to accelerator control systems. It is demonstrated how EPICS Redundant IOC was extended using Hardware Platform Interface specification, which made it possible to utilize benefits of the ATCA platform.

  1. 78 FR 20503 - Energy Conservation Program: Availability of the Interim Technical Support Document for High...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... CFR Part 431 RIN 1904-AC36 Energy Conservation Program: Availability of the Interim Technical Support... interim technical support document (TSD) for high-intensity discharge (HID) lamps energy conservation... submitting comments on the interim TSD or any other aspect of the rulemaking for HID lamps. The...

  2. What's the 411? High School Leaders' Perceptions of Inclusion Implementation

    ERIC Educational Resources Information Center

    Jamison, Arnella L.

    2013-01-01

    This quantitative, descriptive study explored and described urban and suburban school leaders' perceptions of the definition of "inclusion" and perceptions of their level of involvement in the implementation of inclusion. Additionally, the study determined if there was a significant difference in the urban and suburban school leaders'…

  3. High-performance spectral element algorithms and implementations.

    SciTech Connect

    Fischer, P. F.; Tufo, H. M.

    1999-08-28

    We describe the development and implementation of a spectral element code for multimillion gridpoint simulations of incompressible flows in general two- and three-dimensional domains. Parallel performance is present on up to 2048 nodes of the Intel ASCI-Red machine at Sandia.

  4. High content kinetic assays of neuronal signaling implemented on BD pathway HT.

    PubMed

    Chan, Grace K Y; Richards, Gillian R; Peters, Marco; Simpson, Peter B

    2005-12-01

    A great deal of information can be gained from kinetic fluorescence-based measurement of cellular responses; however, until recently the use of such approaches has been limited by the manual nature of the instrumentation available. Higher-throughput kinetic studies of signaling pathways are greatly facilitated by new confocal, liquid handling-enabled, high content screening (HCS) platforms. In the present work, we have implemented one such instrument, the BD(TM) Pathway HT bioimager (BD Biosciences, Rockville, MD), for studying regulation of neuronal signaling pathways. We have established a neuronal calcium oscillation model, whereby rate of oscillation, amplitude of oscillation, and level of synchronicity across the culture can be measured. We have implemented membrane potential measurement using fluorescence resonance energy transfer-based dyes, for single cell characterization on this platform, showing the benefits of a truly flexible excitation and recording system; this dye combination cannot be readily implemented on all HCS platforms because of constraints of excitation wavelengths. We have validated long-term intracellular calcium imaging experiments, using innovative dyes and BD Pathway HT's spinning disk-based confocal excitation. To maximize both throughput and reproducibility, walk-away automation integration of this bioimaging technology has been implemented, producing an affordable, compact platform for fully automated kinetic HCS.

  5. On finite element implementation and computational techniques for constitutive modeling of high temperature composites

    NASA Technical Reports Server (NTRS)

    Saleeb, A. F.; Chang, T. Y. P.; Wilt, T.; Iskovitz, I.

    1989-01-01

    The research work performed during the past year on finite element implementation and computational techniques pertaining to high temperature composites is outlined. In the present research, two main issues are addressed: efficient geometric modeling of composite structures and expedient numerical integration techniques dealing with constitutive rate equations. In the first issue, mixed finite elements for modeling laminated plates and shells were examined in terms of numerical accuracy, locking property and computational efficiency. Element applications include (currently available) linearly elastic analysis and future extension to material nonlinearity for damage predictions and large deformations. On the material level, various integration methods to integrate nonlinear constitutive rate equations for finite element implementation were studied. These include explicit, implicit and automatic subincrementing schemes. In all cases, examples are included to illustrate the numerical characteristics of various methods that were considered.

  6. Implemented data mining and signal management systems on spontaneous reporting systems' databases and their availability to the scientific community - a systematic review.

    PubMed

    de Almeida Vieira Lima, Luis Miguel; Nunes, Nuno Goncalo Sales Craveiro; da Silva Dias, Pedro Goncalo Pires; Marques, Francisco Jorge Batel

    2012-04-01

    Adverse drug reactions' spontaneous reporting systems are an important element in worldwide pharmacovigilance, gathering potentially useful information for post-marketing drug safety surveillance. Data mining and signal management systems, providing the capability of reading and interpreting these systems' raw data (data that has not been subjected to processing or any other manipulation), improve its analysis process. In order for this analysis to be possible, both data mining and signal management systems and raw data should be available to researchers and the scientific community. The purpose of this work was to provide an overview of the spontaneous reporting systems databases reported in literature as having implemented a data mining and signal management system and the implementation itself, evidencing their availability to researchers. A systematic review was carried out, concluding that they are freely provided to researchers within institutions responsible for maintaining the spontaneous reporting systems, but not to most researchers within the scientific community.

  7. Intraspecific competition and high food availability are associated with insular gigantism in a lizard

    NASA Astrophysics Data System (ADS)

    Pafilis, Panayiotis; Meiri, Shai; Foufopoulos, Johannes; Valakos, Efstratios

    2009-09-01

    Resource availability, competition, and predation commonly drive body size evolution. We assess the impact of high food availability and the consequent increased intraspecific competition, as expressed by tail injuries and cannibalism, on body size in Skyros wall lizards ( Podarcis gaigeae). Lizard populations on islets surrounding Skyros (Aegean Sea) all have fewer predators and competitors than on Skyros but differ in the numbers of nesting seabirds. We predicted the following: (1) the presence of breeding seabirds (providing nutrients) will increase lizard population densities; (2) dense lizard populations will experience stronger intraspecific competition; and (3) such aggression, will be associated with larger average body size. We found a positive correlation between seabird and lizard densities. Cannibalism and tail injuries were considerably higher in dense populations. Increases in cannibalism and tail loss were associated with large body sizes. Adult cannibalism on juveniles may select for rapid growth, fuelled by high food abundance, setting thus the stage for the evolution of gigantism.

  8. Intraspecific competition and high food availability are associated with insular gigantism in a lizard.

    PubMed

    Pafilis, Panayiotis; Meiri, Shai; Foufopoulos, Johannes; Valakos, Efstratios

    2009-09-01

    Resource availability, competition, and predation commonly drive body size evolution. We assess the impact of high food availability and the consequent increased intraspecific competition, as expressed by tail injuries and cannibalism, on body size in Skyros wall lizards (Podarcis gaigeae). Lizard populations on islets surrounding Skyros (Aegean Sea) all have fewer predators and competitors than on Skyros but differ in the numbers of nesting seabirds. We predicted the following: (1) the presence of breeding seabirds (providing nutrients) will increase lizard population densities; (2) dense lizard populations will experience stronger intraspecific competition; and (3) such aggression, will be associated with larger average body size. We found a positive correlation between seabird and lizard densities. Cannibalism and tail injuries were considerably higher in dense populations. Increases in cannibalism and tail loss were associated with large body sizes. Adult cannibalism on juveniles may select for rapid growth, fuelled by high food abundance, setting thus the stage for the evolution of gigantism.

  9. Nitrogen saturation and soil N availability in a high-elevation spruce and fir forest

    SciTech Connect

    Garten Jr, Charles T

    2000-06-01

    A field study was conducted during the summer of 1995 to gain abetter understanding of the causes of nitrate (NO{sub 3}-N) leaching and ongoing changes in soil nitrogen (N) availability in high-elevation (1524-2000 m) spruce (Picea rubens) and fir (Abies fraseri) forests of the Great Smoky Mountains National Park, Tennessee and North Carolina, U.S.A. Indicators of soil N availability (total soil N concentrations, extractable NH{sub 4}-N, extractable NO{sub 3}-N, and C/N ratios) were measured in Oa and A horizons at 33 study plots. Dynamic measures included potential net soil N mineralization determined in 12-week aerobic laboratory incubations at 22 C. Potential net nitrification in the A horizon was correlated (r = + 0.83, P < 0.001) with total soil n concentrations. mostmeasures of soil n availability did not exhibit significanttrends with elevation, but there were topographic differences. Potential net soil N mineralization and net nitrification in the A horizon were higher in coves than on ridges. Relative amounts of particulate and organomineral soil organic matter influenced potential net N mineralization and nitrification in the A horizon. Calculations indicate that soil N availability and NO{sub 3}-N leaching in high-elevation spruce and fir forests of the Great Smoky Mountains National Park will increase in response to regional warming.

  10. A Systemic Approach to Implementing Response to Intervention in Three Colorado High Schools

    ERIC Educational Resources Information Center

    Duffy, Helen; Scala, Jenny

    2012-01-01

    The National High School Center continues to receive inquiries about how to support high school implementation of response to intervention (RTI). Given the National High School Center's previous work on the topic, the authors wanted to better understand the conditions that contribute to or inhibit implementation of tiered frameworks in high…

  11. An efficient and high performance linear recursive variable expansion implementation of the Smith-Waterman algorithm.

    PubMed

    Hasan, Laiq; Al-Ars, Zaid

    2009-01-01

    In this paper, we present an efficient and high performance linear recursive variable expansion (RVE) implementation of the Smith-Waterman (S-W) algorithm and compare it with a traditional linear systolic array implementation. The results demonstrate that the linear RVE implementation performs up to 2.33 times better than the traditional linear systolic array implementation, at the cost of utilizing 2 times more resources.

  12. Implementing Schoolwide Positive Behavior Interventions and Supports in High Schools: Contextual Factors and Stages of Implementation

    ERIC Educational Resources Information Center

    Swain-Bradway, Jessica; Pinkney, Christopher; Flannery, K. Brigid

    2015-01-01

    Schoolwide positive behavior interventions and supports (SWPBIS) are an increasingly popular framework for school improvement practices, but many high schools are still lagging behind their elementary counterparts. High school leadership teams can struggle with merging the SWPBIS framework with current operations, and there are limited examples of…

  13. Constellation Ground Systems Launch Availability Analysis: Enhancing Highly Reliable Launch Systems Design

    NASA Technical Reports Server (NTRS)

    Gernand, Jeffrey L.; Gillespie, Amanda M.; Monaghan, Mark W.; Cummings, Nicholas H.

    2010-01-01

    Success of the Constellation Program's lunar architecture requires successfully launching two vehicles, Ares I/Orion and Ares V/Altair, within a very limited time period. The reliability and maintainability of flight vehicles and ground systems must deliver a high probability of successfully launching the second vehicle in order to avoid wasting the on-orbit asset launched by the first vehicle. The Ground Operations Project determined which ground subsystems had the potential to affect the probability of the second launch and allocated quantitative availability requirements to these subsystems. The Ground Operations Project also developed a methodology to estimate subsystem reliability, availability, and maintainability to ensure that ground subsystems complied with allocated launch availability and maintainability requirements. The verification analysis developed quantitative estimates of subsystem availability based on design documentation, testing results, and other information. Where appropriate, actual performance history was used to calculate failure rates for legacy subsystems or comparative components that will support Constellation. The results of the verification analysis will be used to assess compliance with requirements and to highlight design or performance shortcomings for further decision making. This case study will discuss the subsystem requirements allocation process, describe the ground systems methodology for completing quantitative reliability, availability, and maintainability analysis, and present findings and observation based on analysis leading to the Ground Operations Project Preliminary Design Review milestone.

  14. Constellation Ground Systems Launch Availability Analysis: Enhancing Highly Reliable Launch Systems Design

    NASA Technical Reports Server (NTRS)

    Gernand, Jeffrey L.; Gillespie, Amanda M.; Monaghan, Mark W.; Cummings, Nicholas H.

    2010-01-01

    Success of the Constellation Program's lunar architecture requires successfully launching two vehicles, Ares I/Orion and Ares V/Altair, in a very limited time period. The reliability and maintainability of flight vehicles and ground systems must deliver a high probability of successfully launching the second vehicle in order to avoid wasting the on-orbit asset launched by the first vehicle. The Ground Operations Project determined which ground subsystems had the potential to affect the probability of the second launch and allocated quantitative availability requirements to these subsystems. The Ground Operations Project also developed a methodology to estimate subsystem reliability, availability and maintainability to ensure that ground subsystems complied with allocated launch availability and maintainability requirements. The verification analysis developed quantitative estimates of subsystem availability based on design documentation; testing results, and other information. Where appropriate, actual performance history was used for legacy subsystems or comparative components that will support Constellation. The results of the verification analysis will be used to verify compliance with requirements and to highlight design or performance shortcomings for further decision-making. This case study will discuss the subsystem requirements allocation process, describe the ground systems methodology for completing quantitative reliability, availability and maintainability analysis, and present findings and observation based on analysis leading to the Ground Systems Preliminary Design Review milestone.

  15. High-speed dynamic domino circuit implemented with gaas mesfets

    NASA Technical Reports Server (NTRS)

    Yang, Long (Inventor); Long, Stephen I. (Inventor)

    1990-01-01

    A dynamic logic circuit (AND or OR) utilizes one depletion-mode metal-semiconductor FET for precharging an internal node A, and a plurality of the same type of FETs in series, or a FET in parallel with one or more of the series connected FETs for implementing the logic function. A pair of FETs are connected to provide an output inverter with two series diodes for level shift. A coupling capacitor may be employed with a further FET to provide level shifting required between the inverter and the logic circuit output terminal. These circuits may be cascaded to form a domino chain.

  16. Unusually high food availability in Kaikoura Canyon linked to distinct deep-sea nematode community

    NASA Astrophysics Data System (ADS)

    Leduc, D.; Rowden, A. A.; Nodder, S. D.; Berkenbusch, K.; Probert, P. K.; Hadfield, M. G.

    2014-06-01

    Kaikoura Canyon, on the eastern New Zealand continental margin, is the most productive, non-chemosynthetic deep-sea habitat described to date, with megafaunal biomass 100-fold higher than those of other deep-sea habitats. The present study, which focused on free-living nematodes, provides the first comparison of faunal community structure and diversity between Kaikoura Canyon and nearby open slope habitats. Results show substantially higher food availability in the canyon relative to open slope sediments, which probably reflects greater levels of primary productivity above the canyon, coupled with downwelling and/or topographically-induced channelling, which serves to concentrate surface-derived organic matter along the canyon axis. This high food availability appears to be responsible for the elevated nematode biomass in Kaikoura Canyon, with values exceeding all published nematode biomass data from canyons elsewhere. There was also markedly lower local species diversity of nematodes inside the canyon relative to the open slope habitat, as well as a distinct community structure. The canyon community was dominated by species, such as Sabateria pulchra, which were absent from the open slope and are typically associated with highly eutrophic and/or disturbed environments. The presence of these taxa, as well as the low observed diversity, is likely to reflect the high food availability, and potentially the high levels of physically and biologically induced disturbance within the canyon. Kaikoura Canyon is a relatively small habitat characterised by different environmental conditions that makes a disproportionate contribution to deep-sea diversity in the region, despite its low species richness.

  17. Implementation of the high-order schemes QUICK and LECUSSO in the COMMIX-1C Program

    SciTech Connect

    Sakai, K.; Sun, J.G.; Sha, W.T.

    1995-08-01

    Multidimensional analysis computer programs based on the finite volume method, such as COMMIX-1C, have been commonly used to simulate thermal-hydraulic phenomena in engineering systems such as nuclear reactors. In COMMIX-1C, the first-order schemes with respect to both space and time are used. In many situations such as flow recirculations and stratifications with steep gradient of velocity and temperature fields, however, high-order difference schemes are necessary for an accurate prediction of the fields. For these reasons, two second-order finite difference numerical schemes, QUICK (Quadratic Upstream Interpolation for Convective Kinematics) and LECUSSO (Local Exact Consistent Upwind Scheme of Second Order), have been implemented in the COMMIX-1C computer code. The formulations were derived for general three-dimensional flows with nonuniform grid sizes. Numerical oscillation analyses for QUICK and LECUSSO were performed. To damp the unphysical oscillations which occur in calculations with high-order schemes at high mesh Reynolds numbers, a new FRAM (Filtering Remedy and Methodology) scheme was developed and implemented. To be consistent with the high-order schemes, the pressure equation and the boundary conditions for all the conservation equations were also modified to be of second order. The new capabilities in the code are listed. Test calculations were performed to validate the implementation of the high-order schemes. They include the test of the one-dimensional nonlinear Burgers equation, two-dimensional scalar transport in two impinging streams, von Karmann vortex shedding, shear driven cavity flow, Couette flow, and circular pipe flow. The calculated results were compared with available data; the agreement is good.

  18. High Availability On-line Relational Databases for Accelerator Control and Operation

    SciTech Connect

    Dohan,D.; Dalesio, L.; Carcassi, G.

    2009-05-04

    The role that relational database (RDB) technology plays in accelerator control and operation continues to grow in such areas as electronic logbooks, machine parameter definitions, and facility infrastructure management. RDBs are increasingly relied upon to provide the official 'master' copy of these data. Whereas the services provided by the RDB have traditionally not been 'mission critical', the availability of modern RDB management systems is now equivalent to that of standard computer file-systems. RDBs can be relied on to supply pseudo real-time response to operator and machine physicist requests. This paper describes recent developments in the IRMIS RDB project. Generic lattice support has been added, serving as the driver for model-based machine control. Abstract physics name service and process variable introspection has been added. Specific emphasis has been placed both on providing fast response time to accelerator operators and modeling code requests, as well as high (24/7) availability of the RDB service.

  19. Research on high availability architecture of SQL and NoSQL

    NASA Astrophysics Data System (ADS)

    Wang, Zhiguo; Wei, Zhiqiang; Liu, Hao

    2017-03-01

    With the advent of the era of big data, amount and importance of data have increased dramatically. SQL database develops in performance and scalability, but more and more companies tend to use NoSQL database as their databases, because NoSQL database has simpler data model and stronger extension capacity than SQL database. Almost all database designers including SQL database and NoSQL database aim to improve performance and ensure availability by reasonable architecture which can reduce the effects of software failures and hardware failures, so that they can provide better experiences for their customers. In this paper, I mainly discuss the architectures of MySQL, MongoDB, and Redis, which are high available and have been deployed in practical application environment, and design a hybrid architecture.

  20. Innovative use of controlled availability fertilizers with high performance for intensive agriculture and environmental conservation.

    PubMed

    Shoji, Sadao

    2005-12-01

    A variety of slow release fertilizers, controlled release (availability) fertilizers (CAFs), and stability fertilizers have been developed in response to the serious drawbacks of the conventional fertilizers since the early 1960's. Of these fertilizers, CAFs which are coated with resin are consumed in the largest quantity in the world. Selecting CAFs with higher performance, the author will discuss about: 1) Innovation of agro-technologies for various field crops including new concepts of fertilizer application, 2) high yielding of field crops, 3) enhancing quality and safety of farm products, and 4) controlling the adverse effect of intensive agriculture on the environment.

  1. Innovative use of controlled availability fertilizers with high performance for intensive agriculture and environmental conservation.

    PubMed

    Shoji, Sadao

    2005-09-01

    A variety of slow release fertilizers, controlled release (availability) fertilizers (CAFs), and stability fertilizers have been developed in response to the serious drawbacks of the conventional fertilizers since the early 1960's. Of these fertilizers, CAFs which are coated with resin are consumed in the largest quantity in the world. Selecting CAFs with higher performance, the author will discuss about: 1) Innovation of agro-technologies for various field crops including new concepts of fertilizer application, 2) high yielding of field crops, 3) enhancing quality and safety of farm products, and 4) controlling the adverse effect of intensive agriculture on the environment.

  2. Design and Implementation of High-Throughput Screening Assays.

    PubMed

    Powell, David J; Hertzberg, Robert P; Macarrόn, Ricardo

    2016-01-01

    HTS remains at the core of the drug discovery process, and so it is critical to design and implement HTS assays in a comprehensive fashion involving scientists from the disciplines of biology, chemistry, engineering, and informatics. This requires careful consideration of many options and variables, starting with the choice of screening strategy and ending with the discovery of lead compounds. At every step in this process, there are decisions to be made that can greatly impact the outcome of the HTS effort, to the point of making it a success or a failure. Although specific guidelines should be established to ensure that the screening assay reaches an acceptable level of quality, many choices require pragmatism and the ability to compromise opposing forces.

  3. High-frequency nutrient monitoring to infer seasonal patterns in catchment source availability, mobilisation and delivery.

    PubMed

    Bende-Michl, Ulrike; Verburg, Kirsten; Cresswell, Hamish P

    2013-11-01

    To explore the value of high-frequency monitoring to characterise and explain riverine nutrient concentration dynamics, total phosphorus (TP), reactive phosphorus (RP), ammonium (NH4-N) and nitrate (NO3-N) concentrations were measured hourly over a 2-year period in the Duck River, in north-western Tasmania, Australia, draining a 369-km(2) mixed land use catchment area. River discharge was observed at the same location and frequency, spanning a wide range of hydrological conditions. Nutrient concentrations changed rapidly and were higher than previously observed. Maximum nutrient concentrations were 2,577 μg L(-1) TP, 1,572 μg L(-1) RP, 972 μg L(-1) NH₄-N and 1,983 μg L(-1) NO₃-N, respectively. Different nutrient response patterns were evident at seasonal, individual event and diurnal time scales-patterns that had gone largely undetected in previous less frequent water quality sampling. Interpretation of these patterns in terms of nutrient source availability, mobilisation and delivery to the stream allowed the development of a conceptual model of catchment nutrient dynamics. Functional stages of nutrient release were identified for the Duck River catchment and were supported by a cluster analysis which confirmed the similarities and differences in nutrient responses caused by the sequence of hydrologic events: (1) a build-up of nutrients during periods with low hydrologic activity, (2) flushing of readily available nutrient sources at the onset of the high flow period, followed by (3) a switch from transport to supply limitation, (4) the accessibility of new nutrient sources with increasing catchment wetness and hydrologic connectivity and (5) high nutrient spikes occurring when new sources become available that are easily mobilised with quickly re-established hydrologic connectivity. Diurnal variations that could be influenced by riverine processes and/or localised point sources were also identified as part of stage (1) and during late recession of some of

  4. The research and design for a high availability object storage system

    NASA Astrophysics Data System (ADS)

    Zhan, Ling; Tan, Zhihu; Gu, Peng; Wan, Jiguang

    2008-12-01

    With the growing scale of the computer storage systems, the likelihood of multi-disk failures happening in the storage systems has increased dramatically. Based on a thorough analysis on the fault-tolerance capability on various existing storage systems, we propose a new hierarchical, highly reliable, multi-disk fault-tolerant storage system architecture: High Availability Object Storage System (HAOSS). In the HAOSS, each object has an attribute field for reliability level, which can be set by the user according to the importance of data. Higher reliability level corresponds to better data survivability in case of multi-device failure. The HAOSS is composed of two layers: the upper-layer and the lower-layer. The upper-layer achieves the high availability by storing multiple replicas for each storage object in a set of storage devices. The individual replicas can service the I/O requests in parallel so as to obtain high performance. The lower-layer deploys RAID5, RAID6 or RAID_Blaum coding schemes to tolerate multi-disk failures. In addition, the disk utilization rate of RAID_Blaum is higher than that of multiple replicas, and it can be further improved by growing the RAID group size. These advantages come at the price of more complicated fault-tolerant coding schemes, which involve a large amount of calculation for encoding and cause an adverse impact on the I/O performance, especially on the write performance. Results from both our internal experiments and third-party independent tests have shown that HAOSS servers have better multi-disk- failure tolerance than existing similar products. In a 1000Mb Ethernet interconnection environment, with a request block size of 1024KB, the sequential read performance for a HAOSS server reaches 104MB/s, which is very close to the theoretical maximum effective bandwidth of Ethernet networks. The HAOSS offers a complete storage solution for high availability applications without the compromises that today's storage systems

  5. High School Principals' Rating of Success in Implementation of 21st Century Skills

    ERIC Educational Resources Information Center

    Sam, Sonn

    2011-01-01

    The purpose of this quantitative study was to investigate how Rhode Island high school principals rate success in implementing 21st century skills in their schools. Secondly, this study investigated how high school principals rate the influence of implementing of 21st century skills in curriculum and instruction in their schools. The high…

  6. Tech Prep Implementation. Self-Assessment Inventory. Middle/High School Level. Postsecondary Level.

    ERIC Educational Resources Information Center

    Partnership for Academic and Career Education, Pendleton, SC.

    These two self-assessment inventories are designed to be used for evaluation of tech prep implementation at the middle/high school and postsecondary levels. The middle/high school version is intended to be completed by the district/school, the postsecondary form by the technical college. The form provides for rating the level of implementation as…

  7. Career Guidance: An Implementation Model for Small High Schools. A Maxi I Practicum.

    ERIC Educational Resources Information Center

    Stevens, Richard; And Others

    The purpose of this practicum was to design, develop, and implement a career guidance program for small high schools. The program description would act as a model for implementation at other high schools desiring a career guidance program. The method of communicating the program to others was the writing of a "how to" book which others would use…

  8. Successful Strategies for Implementation of a High School Standards-Based Integrated Mathematics Curriculum

    ERIC Educational Resources Information Center

    Brown, Linda

    2012-01-01

    Math achievement for students in the United States is not as high as in other countries. In response, one state implemented a new standards-based, integrated math curriculum that combines traditional high school math courses and emphasizes student centered instruction. The purpose of this study was to examine the implementation of a standards…

  9. Sexually transmitted infections treatment and care available to high risk populations in Pakistan.

    PubMed

    Rahimtoola, Minal; Hussain, Hamidah; Khowaja, Saira N; Khan, Aamir J

    2008-01-01

    Limited literature exists on the quality and availability of treatment and care of sexually transmitted infections (STIs) in Pakistan. This article aims to document existing services for the care and treatment of STIs available in Pakistan's public and private sectors to high risk groups (HRG), particularly the transgendered population. We conducted a cross-sectional survey to document STI services in Lahore, Karachi, Rawalpindi, Peshawar, and Quetta. Seventy-three interviews were administered with health service providers at the 3 largest public sector hospitals in each city, as well as with general physicians and traditional healers in the private sector. Twenty-five nongovernmental organizations (NGO) providing STI services were also interviewed. Fewer than 45% of private and public sector general practitioners had been trained in STI treatment after the completion of their medical curriculum, and none of the traditional healers had received any formal training or information on STIs. The World Health Organization (WHO) syndromic management guidelines were followed for STI management by 29% of public and private sector doctors and 5% of traditional healers. STI drugs were available at no cost at 44% of NGOs and at some public sector hospitals. Our findings show that although providers do treat HRGs for STIs, there are significant limitations in their ability to provide these services. These deterrents include, but are not limited to, a lack of STI training of service providers, privacy and adherence to recommended WHO syndromic management guidelines, and costly diagnostic and consultation fees.

  10. Designing a high-availability cluster for the Subaru Telescope second generation observation control system

    NASA Astrophysics Data System (ADS)

    Jeschke, Eric; Inagaki, Takeshi

    2010-07-01

    Subaru Telescope is commissioning a second-generation Observation Control System (OCS), building upon a 10 hear history of using the first generation OCS. One of the primary lessons learned about maintaining a distributed OCS system is that the idea of individual computer nodes specialized for specific functions greatly complicates troubleshooting and failover, even with a dedicated "hot spare" for each specialized node. In contrast, the Generation 2 (Gen2) system was designed from the ground up around the principle of a High-Availability (HA) cluster, commonly used for high-traffic, mission-critical web sites. In such a cluster, nodes are not specialized, and any node can perform any function of the OCS. We describe the problems encountered in trying to troubleshoot and manage failure on the legacy OCS system and describe the architectural design of the HA cluster for the new system, including special characteristics designed for the high-altitude, remote environment of the summit of Mauna Kea, where there is a greatly increased probability of such failures. Although the focus is primarily on the hardware, we touch upon the software architecture written to take advantage of the features of the HA cluster design. Finally, we outline the advantages of the new system and show how the design greatly facilitates troubleshooting, robustness and ease of failure management. The results may be of interest to anyone designing a distributed system using COTS hardware and open-source software to withstand failure and improve manageability in a remote environment.

  11. High responsivity CMOS imager pixel implemented in SOI technology

    NASA Technical Reports Server (NTRS)

    Zheng, X.; Wrigley, C.; Yang, G.; Pain, B.

    2000-01-01

    Availability of mature sub-micron CMOS technology and the advent of the new low noise active pixel sensor (APS) concept have enabled the development of low power, miniature, single-chip, CMOS digital imagers in the decade of the 1990's.

  12. High sensitivity of broadleaf trees to water availability in northeastern United States

    NASA Astrophysics Data System (ADS)

    Levesque, Mathieu; Andreu-Hayles, Laia; Pederson, Neil

    2016-04-01

    Broadleaf dominated forests of eastern US cover more than one million km2 and provide ecosystem services to millions of people. High species diversity and a varied sensitivity to drought make it uncertain whether these forests will be carbon sinks or sources under climate change. Ongoing climate change, increased in atmospheric CO2 concentration (ca) and strong reductions in acidic depositions are expected to alter growth and gas exchange of trees, and ultimately forest productivity. Still, the magnitude of these effects is unclear. A better comprehension of the species-specific responses to environmental changes will better inform models and managers on the vulnerability and resiliency of these forests. Here, we combined tree-ring width data with δ13C and δ18O measurements to investigate growth and physiological responses of red oak (Quercus rubra L.) and tulip poplar (Liriodendron tulipifera L.) in northeastern US to changes in water availability, ca and acidic depositions for the period 1950-2014. Based on structural equation modeling approaches, we found that summer water availability (June-August) is the main environmental variable driving growth, water-use efficiency and δ18O of broadleaf trees whereas ca and acidic depositions have little effects. This high sensitivity to moisture availability was also supported by the very strong correlations found between summer vapor pressure deficit (VPD) and tree-ring δ13C (r = 0.67 and 0.71), and δ18O series (r = 0.62 and 0.72), for red oak and tulip poplar, respectively. In contrast, tree-ring width was less sensitive to summer VPD (r = -0.44 and-0.31). Since the mid 1980s, pluvial conditions occurring in northeastern US have increased stomatal conductance, carbon uptake, and growth of both species. Further, the strong spatial field correlations found between the tree-ring δ13C and δ18O and summer VPD indicate a greater sensitivity of eastern US broadleaf forests to moisture availability than previously known

  13. High performance computing and communications: FY 1997 implementation plan

    SciTech Connect

    1996-12-01

    The High Performance Computing and Communications (HPCC) Program was formally authorized by passage, with bipartisan support, of the High-Performance Computing Act of 1991, signed on December 9, 1991. The original Program, in which eight Federal agencies participated, has now grown to twelve agencies. This Plan provides a detailed description of the agencies` FY 1996 HPCC accomplishments and FY 1997 HPCC plans. Section 3 of this Plan provides an overview of the HPCC Program. Section 4 contains more detailed definitions of the Program Component Areas, with an emphasis on the overall directions and milestones planned for each PCA. Appendix A provides a detailed look at HPCC Program activities within each agency.

  14. Planning and Implementing a High Performance Knowledge Base.

    ERIC Educational Resources Information Center

    Cortez, Edwin M.

    1999-01-01

    Discusses the conceptual framework for developing a rapid-prototype high-performance knowledge base for the four mission agencies of the United States Department of Agriculture and their university partners. Describes the background of the project and methods used for establishing the requirements; examines issues and problems surrounding semantic…

  15. Implementing Concepts of Pharmaceutical Engineering into High School Science Classrooms

    ERIC Educational Resources Information Center

    Kimmel, Howard; Hirsch, Linda S.; Simon, Laurent; Burr-Alexander, Levelle; Dave, Rajesh

    2009-01-01

    The Research Experience for Teachers was designed to help high school science teachers develop skills and knowledge in research, science and engineering with a focus on the area of pharmaceutical particulate and composite systems. The experience included time for the development of instructional modules for classroom teaching. Results of the…

  16. A software and hardware architecture for a high-availability PACS.

    PubMed

    Gutiérrez-Martínez, Josefina; Núñez-Gaona, Marco Antonio; Aguirre-Meneses, Heriberto; Delgado-Esquerra, Ruth Evelin

    2012-08-01

    Increasing radiology studies has led to the emergence of new requirements for management medical information, mainly affecting the storage of digital images. Today, it is a necessary interaction between workflow management and legal rules that govern it, to allow an efficient control of medical technology and associated costs. Another important topic that is growing in importance within the healthcare sector is compliance, which includes the retention of studies, information security, and patient privacy. Previously, we conducted a series of extensive analysis and measurements of pre-existing operating conditions. These studies and projects have been described in other papers. The first phase: hardware and software installation and initial tests were completed in March 2006. The storage phase was built step by step until the PACS-INR was totally completed. Two important aspects were considered in the integration of components: (1) the reliability and performance of the system to transfer and display DICOM images, and (2) the availability of data backups for disaster recovery and downtime scenarios. This paper describes the high-availability model for a large-scale PACS to support the storage and retrieve of data using CAS and DAS technologies to provide an open storage platform. This solution offers a simple framework that integrates and automates the information at low cost and minimum risk. Likewise, the model allows an optimized use of the information infrastructure in the clinical environment. The tests of the model include massive data migration, openness, scalability, and standard compatibility to avoid locking data into a proprietary technology.

  17. Stimulated growth rate by restriction of P availability at moderate salinity but insensitive to P availability at high salinity in Crithmum maritimum.

    PubMed

    Labidi, Nehla; Ammari, Manel; Snoussi, Sana; Messelini, Najoua; Gharbi, Fatma; Abdelly, C

    2011-09-01

    The halophyte Crithmum maritimum thrives in cracks of calcareous rocks or cliffs at seashores, a situation which associates limited phosphorus availability and high salinity. In order to understand the common patterns of colonization and zonation of this species, seedlings were cultivated for 34 d in inert sandy soil irrigated with a nutrient solution containing or not phosphorus at moderate (50 mM) or high (250 mM) NaCl level. Net assimilation rate and consequently relative growth rate increased in response to P deprivation at moderate saline level, but not at high salinity level. Parallelly, CO2 fixation rate, rubisco capacity, transpiration rate and stomatal conductance were diminished by P deprivation at moderate NaCl level. Intercellular CO2 concentration was therefore not affected. Chlororophyll fluorescence analysis revealed that photosynthetic systems were insensitive to change in P availability at moderate salinity level: neither pigment content, nor effective and maximum quantum yield, photochemical and non photochemical quenching, and electron transport rate were affected by P deprivation. On the contrary, at high salinity level when net photosynthesis, rubisco capacity and the quantum yields of PS2 were severely affected, P deprivation strongly augmented electron transport rate. Stomatal aperture and more modest increase in net photosynthesis, rubisco capacity, photosystem II effective quantum yield and photochemical quenching accompanied this response. This study shows the tolerance of C. maritimum to the phosphorus deprivation combined to moderate or to high saline level which may explain the common patterns of colonization and zonation of this species.

  18. Implementing high-performance work practices in healthcare organizations: qualitative and conceptual evidence.

    PubMed

    McAlearney, Ann Scheck; Robbins, Julie; Garman, Andrew N; Song, Paula H

    2013-01-01

    Studies across industries suggest that the systematic use of high-performance work practices (HPWPs) may be an effective but underused strategy to improve quality of care in healthcare organizations. Optimal use of HPWPs depends on how they are implemented, yet we know little about their implementation in healthcare. We conducted 67 key informant interviews in five healthcare organizations, each considered to have exemplary work practices in place and to deliver high-quality care, as part of an extensive study of HPWP use in healthcare. We analyzed interview transcripts inductively and deductively to examine why and how organizations implement HPWPs. We used an evidence-based model of complex innovation adoption to guide our exploration of factors that facilitate HPWP implementation. We found considerable variability in interviewees' reasons for implementing HPWPs, including macro-organizational (strategic level) and micro-organizational (individual level) reasons. This variability highlighted the complex context for HPWP implementation in many organizations. We also found that our application of an innovation implementation model helped clarify and categorize facilitators of HPWP implementation, thus providing insight on how these factors can contribute to implementation effectiveness. Focusing efforts on clarifying definitions, building commitment, and ensuring consistency in the application of work practices may be particularly important elements of successful implementation.

  19. High speed fiber optics local area networks: Design and implementation

    NASA Technical Reports Server (NTRS)

    Tobagi, Fouad A.

    1988-01-01

    The design of high speed local area networks (HSLAN) for communication among distributed devices requires solving problems in three areas: (1) the network medium and its topology; (2) the medium access control; and (3) the network interface. Considerable progress has been made in all areas. Accomplishments are divided into two groups according to their theoretical or experimental nature. A brief summary is given in Section 2, including references to papers which appeared in the literature, as well as to Ph.D. dissertations and technical reports published at Stanford University.

  20. High fatty acid availability after exercise alters the regulation of muscle lipid metabolism.

    PubMed

    Newsom, Sean A; Schenk, Simon; Li, Minghua; Everett, Allison C; Horowitz, Jeffrey F

    2011-06-01

    We previously reported that a single exercise session protects against fatty acid (FA)-induced insulin resistance, perhaps in part through augmented intramyocellular triacylglycerol (IMTG) synthesis. The aim of this study was to examine the effect of elevated FA availability after exercise on factors regulating IMTG metabolism. After exercise (90 minutes, 65% peak oxygen uptake), 7 healthy women (body mass index, 23 ± 1 kg/m(2)) were infused overnight (16 hours) with either a lipid and heparin solution (LIPID, 0.11 g fat per kilogram per hour) or saline (SALINE). We measured resting FA oxidation (indirect calorimetry) and obtained a skeletal muscle biopsy sample the next morning. The 4-fold increase in overnight plasma FA concentration during LIPID increased IMTG by approximately 30% during LIPID vs SALINE. This was accompanied by an approximately 25% greater membrane-associated abundance of the FA transporter FAT/CD36 (P < .01) and an approximately 8% increase in the activity of the IMTG synthesis enzyme glycerol-3-phosphate acyltransferase (GPAT, P < .01). In contrast, resting FA oxidation was not affected. We also found no difference in the protein abundance of GPAT1 and diacylglycerol acyltransferase-1, diacylglycerol acyltransferase activity, or the abundance of the lipid droplet coat proteins (perilipins 2, 3, 4, and 5) between treatments. Our findings suggest that augmented capacity for FA flux into muscle (ie, via membrane-associated FAT/CD36), perhaps together with a slight yet significant increase in activity of a key IMTG synthesis enzyme (GPAT), may enhance IMTG storage when FA availability is high after exercise. The importance of the absence of a change in perilipin protein abundance despite increased muscle lipid storage remains to be determined.

  1. Self-Study Guide for Implementing High School Academic Interventions. REL 2016-218

    ERIC Educational Resources Information Center

    Smith, Kevin G.; Dombek, Jennifer L.; Foorman, Barbara R.; Hook, Karl S.; Lee, Laurie; Cote, Anna-Marie; Sanabria, Israel; Stafford, Tammy

    2016-01-01

    While academic interventions can be implemented in any grade, focusing on interventions in high school is critical because it is often a student's last chance to become ready for the academic demands of postsecondary education and careers. States across the country are implementing large-scale initiatives focused on delivering academic…

  2. Teachers' Perceptions and Implementation of Professional Learning Communities in a Large Suburban High School

    ERIC Educational Resources Information Center

    Peppers, Gloria J.

    2014-01-01

    The purpose of this study was to explore teachers' perceptions prior to the implementation of professional learning communities (PLCs) and after the implementation of PLCs in a large suburban high school. The goal was to provide information that focused on (a) retention and achievement of students, (b) retention of teachers, and (c) teachers'…

  3. The Implementation of High-Leverage Teaching Practices: From the University Classroom to the Field Site

    ERIC Educational Resources Information Center

    Davin, Kristin J.; Troyan, Francis J.

    2015-01-01

    In response to the ACTFL's Research Priorities Initiative, the present study used a multiple case study design to examine teacher candidates' ability to implement two high-leverage teaching practices: increasing interaction and target language comprehensibility and questioning to build and assess student understanding. Candidates implemented these…

  4. Implementing a High-Assurance Smart-Card OS

    NASA Astrophysics Data System (ADS)

    Karger, Paul A.; Toll, David C.; Palmer, Elaine R.; McIntosh, Suzanne K.; Weber, Samuel; Edwards, Jonathan W.

    Building a high-assurance, secure operating system for memory constrained systems, such as smart cards, introduces many challenges. The increasing power of smart cards has made their use feasible in applications such as electronic passports, military and public sector identification cards, and cell-phone based financial and entertainment applications. Such applications require a secure environment, which can only be provided with sufficient hardware and a secure operating system. We argue that smart cards pose additional security challenges when compared to traditional computer platforms. We discuss our design for a secure smart card operating system, named Caernarvon, and show that it addresses these challenges, which include secure application download, protection of cryptographic functions from malicious applications, resolution of covert channels, and assurance of both security and data integrity in the face of arbitrary power losses.

  5. ArcticDEM; A Publically Available, High Resolution Elevation Model of the Arctic

    NASA Astrophysics Data System (ADS)

    Morin, Paul; Porter, Claire; Cloutier, Michael; Howat, Ian; Noh, Myoung-Jong; Willis, Michael; Bates, Brian; Willamson, Cathleen; Peterman, Kennith

    2016-04-01

    A Digital Elevation Model (DEM) of the Arctic is needed for a large number of reasons, including: measuring and understanding rapid, ongoing changes to the Arctic landscape resulting from climate change and human use and mitigation and adaptation planning for Arctic communities. The topography of the Arctic is more poorly mapped than most other regions of Earth due to logistical costs and the limits of satellite missions with low-latitude inclinations. A convergence of civilian, high-quality sub-meter stereo imagery; petascale computing and open source photogrammetry software has made it possible to produce a complete, very high resolution (2 to 8-meter posting), elevation model of the Arctic. A partnership between the US National Geospatial-intelligence Agency and a team led by the US National Science Foundation funded Polar Geospatial Center is using stereo imagery from DigitalGlobe's Worldview-1, 2 and 3 satellites and the Ohio State University's Surface Extraction with TIN-based Search-space Minimization (SETSM) software running on the University of Illinois's Blue Water supercomputer to address this challenge. The final product will be a seemless, 2-m posting digital surface model mosaic of the entire Arctic above 60 North including all of Alaska, Greenland and Kamchatka. We will also make available the more than 300,000 individual time-stamped DSM strip pairs that were used to assemble the mosaic. The Arctic DEM will have a vertical precision of better than 0.5m and can be used to examine changes in land surfaces such as those caused by permafrost degradation or the evolution of arctic rivers and floodplains. The data set can also be used to highlight changing geomorphology due to Earth surface mass transport processes occurring in active volcanic and glacial environments. When complete the ArcticDEM will catapult the Arctic from the worst to among the best mapped regions on Earth.

  6. Computational Environments and Analysis methods available on the NCI High Performance Computing (HPC) and High Performance Data (HPD) Platform

    NASA Astrophysics Data System (ADS)

    Evans, B. J. K.; Foster, C.; Minchin, S. A.; Pugh, T.; Lewis, A.; Wyborn, L. A.; Evans, B. J.; Uhlherr, A.

    2014-12-01

    The National Computational Infrastructure (NCI) has established a powerful in-situ computational environment to enable both high performance computing and data-intensive science across a wide spectrum of national environmental data collections - in particular climate, observational data and geoscientific assets. This paper examines 1) the computational environments that supports the modelling and data processing pipelines, 2) the analysis environments and methods to support data analysis, and 3) the progress in addressing harmonisation of the underlying data collections for future transdisciplinary research that enable accurate climate projections. NCI makes available 10+ PB major data collections from both the government and research sectors based on six themes: 1) weather, climate, and earth system science model simulations, 2) marine and earth observations, 3) geosciences, 4) terrestrial ecosystems, 5) water and hydrology, and 6) astronomy, social and biosciences. Collectively they span the lithosphere, crust, biosphere, hydrosphere, troposphere, and stratosphere. The data is largely sourced from NCI's partners (which include the custodians of many of the national scientific records), major research communities, and collaborating overseas organisations. The data is accessible within an integrated HPC-HPD environment - a 1.2 PFlop supercomputer (Raijin), a HPC class 3000 core OpenStack cloud system and several highly connected large scale and high-bandwidth Lustre filesystems. This computational environment supports a catalogue of integrated reusable software and workflows from earth system and ecosystem modelling, weather research, satellite and other observed data processing and analysis. To enable transdisciplinary research on this scale, data needs to be harmonised so that researchers can readily apply techniques and software across the corpus of data available and not be constrained to work within artificial disciplinary boundaries. Future challenges will

  7. Assessment of commercially available ion exchange materials for cesium removal from highly alkaline wastes

    SciTech Connect

    Brooks, K.P.; Kim, A.Y.; Kurath, D.E.

    1996-04-01

    Approximately 61 million gallons of nuclear waste generated in plutonium production, radionuclide removal campaigns, and research and development activities is stored on the Department of Energy`s Hanford Site, near Richland, Washington. Although the pretreatment process and disposal requirements are still being defined, most pretreatment scenarios include removal of cesium from the aqueous streams. In many cases, after cesium is removed, the dissolved salt cakes and supernates can be disposed of as LLW. Ion exchange has been a leading candidate for this separation. Ion exchange systems have the advantage of simplicity of equipment and operation and provide many theoretical stages in a small space. The organic ion exchange material Duolite{trademark} CS-100 has been selected as the baseline exchanger for conceptual design of the Initial Pretreatment Module (IPM). Use of CS-100 was chosen because it is considered a conservative, technologically feasible approach. During FY 96, final resin down-selection will occur for IPM Title 1 design. Alternate ion exchange materials for cesium exchange will be considered at that time. The purpose of this report is to conduct a search for commercially available ion exchange materials which could potentially replace CS-100. This report will provide where possible a comparison of these resin in their ability to remove low concentrations of cesium from highly alkaline solutions. Materials which show promise can be studied further, while less encouraging resins can be eliminated from consideration.

  8. Energy balance of a high marsh on the Texas Gulf Coast: Effect of water availability

    NASA Astrophysics Data System (ADS)

    Heilman, J. L.; Heinsch, F. A.; Cobos, D. R.; McInnes, K. J.

    2000-09-01

    The supply of water to the Nueces River Delta near Corpus Christi, Texas, and its estuarine marshes is limited by low tidal ranges in the Gulf of Mexico and by channelization of the Nueces River which restricts freshwater inflow. Micrometeorological measurements were made at the upper end (high marsh) of the delta to determine how daily and seasonal changes in the surface energy balance were affected by availability of water. The marsh consists of shallow ponds interconnected by narrow channels, and elevated areas containing emergent vegetation. During the spring and fall when ponds were flooded, latent and sensible heat flux averaged 67% and 30%, respectively, of net radiation. In the summer when ponds dried, energy partitioning was reversed with sensible heat flux accounting for 65% of net radiation and latent heat accounting for 27%. When ponds were flooded, heat storage in the water column was the major component of storage heat flux. When ponds dried, storage heat flux was controlled by sediment water content, largely through its effect on thermal diffusivity. The ratio of actual to equilibrium evaporation averaged 0.7 in the spring and fall, and 0.3 in the summer, indicating that the marsh behaved more like a dryland ecosystem than a wetland.

  9. The implementation of sea ice model on a regional high-resolution scale

    NASA Astrophysics Data System (ADS)

    Prasad, Siva; Zakharov, Igor; Bobby, Pradeep; McGuire, Peter

    2015-09-01

    The availability of high-resolution atmospheric/ocean forecast models, satellite data and access to high-performance computing clusters have provided capability to build high-resolution models for regional ice condition simulation. The paper describes the implementation of the Los Alamos sea ice model (CICE) on a regional scale at high resolution. The advantage of the model is its ability to include oceanographic parameters (e.g., currents) to provide accurate results. The sea ice simulation was performed over Baffin Bay and the Labrador Sea to retrieve important parameters such as ice concentration, thickness, ridging, and drift. Two different forcing models, one with low resolution and another with a high resolution, were used for the estimation of sensitivity of model results. Sea ice behavior over 7 years was simulated to analyze ice formation, melting, and conditions in the region. Validation was based on comparing model results with remote sensing data. The simulated ice concentration correlated well with Advanced Microwave Scanning Radiometer for EOS (AMSR-E) and Ocean and Sea Ice Satellite Application Facility (OSI-SAF) data. Visual comparison of ice thickness trends estimated from the Soil Moisture and Ocean Salinity satellite (SMOS) agreed with the simulation for year 2010-2011.

  10. On the use of fuzzy logic assessment for high consequence implementation risk analysis

    SciTech Connect

    Spray, S.; Cooper, A.; Bennett, R.

    1994-05-01

    ``High consequence`` operations are systems, structures, and/or strategies for which it is crucial to provide assured protection against some potential catastrophe or catastrophes. The word ``catastrophe`` implies a significant loss of a resource (e.g., money, lives, health, environment, national security, etc.). The implementation of operations that are to be as catastrophe-free as possible must incorporate a very high level of protection. Unfortunately, real world limitations on available resources, mainly money and time, preclude absolute protection. For this reason, conventional ``risk analysis`` focuses on ``cost-effective`` protection, demonstrating through analysis that the benefits of any protective measures chosen outweigh their cost. This is a ``crisp`` one-parameter (usually monetary) comparison. A major problem with this approach, especially for high consequence operations, is that it may not be possible to accurately determine quantitative ``costs,`` and furthermore, the costs may not be accurately quantifiable. Similarly, it may not be possible to accurately determine or to quantify the benefits of protection in high consequence operations. These weaknesses are addressed in this paper by introducing multiple parameters instead of a single monetary measure both for costs of implementing protective measures and their benefits. In addition, a fuzzy-algebra comparison based on fuzzy number theory is introduced as a tool in providing cost/benefit tradeoff depiction, with the incorporation of measures of the uncertainty that necessarily exists in the input information. The result allows a more informative comparison to be made through use of fuzzy results, especially at the extreme bounds of the uncertainty.

  11. The Availability of Competitive Foods and Beverages to Middle School Students in Appalachian Virginia Before Implementation of the 2014 Smart Snacks in School Standards

    PubMed Central

    Kraak, Vivica; Serrano, Elena

    2015-01-01

    The study objective was to examine the nutritional quality of competitive foods and beverages (foods and beverages from vending machines and à la carte foods) available to rural middle school students, before implementation of the US Department of Agriculture’s Smart Snacks in School standards in July 2014. In spring 2014, we audited vending machines and à la carte cafeteria foods and beverages in 8 rural Appalachian middle schools in Virginia. Few schools had vending machines. Few à la carte and vending machine foods met Smart Snacks in School standards (36.6%); however, most beverages did (78.2%). The major challenges to meeting standards were fat and sodium content of foods. Most competitive foods (63.4%) did not meet new standards, and rural schools with limited resources will likely require assistance to fully comply. PMID:26378899

  12. The Availability of Competitive Foods and Beverages to Middle School Students in Appalachian Virginia Before Implementation of the 2014 Smart Snacks in School Standards.

    PubMed

    Mann, Georgianna; Kraak, Vivica; Serrano, Elena

    2015-09-17

    The study objective was to examine the nutritional quality of competitive foods and beverages (foods and beverages from vending machines and à la carte foods) available to rural middle school students, before implementation of the US Department of Agriculture's Smart Snacks in School standards in July 2014. In spring 2014, we audited vending machines and à la carte cafeteria foods and beverages in 8 rural Appalachian middle schools in Virginia. Few schools had vending machines. Few à la carte and vending machine foods met Smart Snacks in School standards (36.5%); however, most beverages did (78.2%). The major challenges to meeting standards were fat and sodium content of foods. Most competitive foods (62.2%) did not meet new standards, and rural schools with limited resources will likely require assistance to fully comply.

  13. Estimating photosynthesis with high resolution field spectroscopy in a Mediterranean grassland under different nutrient availability

    NASA Astrophysics Data System (ADS)

    Perez-Priego, O.; Guan, J.; Fava, F.; Rossini, M.; Wutzler, T.; Moreno, G.; Carrara, A.; Kolle, O.; Schrumpf, M.; Reichstein, M.; Migliavacca, M.

    2014-12-01

    Recent studies have shown how human induced N:P imbalances are affecting essential processes (e.g. photosynthesis, plant growth rate) that lead to important changes in ecosystem structure and function. In this regard, the accuracy of the approaches based on remotely-sensed data for monitoring and modeling gross primary production (GPP) relies on the ability of vegetation indices (VIs) to track the dynamics of vegetation physiological and biophysical properties/variables. Promising results have been recently obtained when Chlorophyll-sensitive VIs and Chlorophyll fluorescence are combined with structural indices in the framework of the Monteith's light use efficiency (LUE) model. However, further ground-based experiments are required to validate LUE model performances, and their capability to be generalized under different nutrient availability conditions. In this study, the overall objective was to investigate the sensitivity of VIs to track short- and long-term GPP variations in a Mediterranean grassland under different N and P fertilization treatments. Spectral VIs were acquired manually using high resolution spectrometers (HR4000, OceanOptics, USA) along a phenological cycle. The VIs examined included photochemical reflectance index (PRI), MERIS terrestrial-chlorophyll index (MTCI) and normalized difference vegetation index (NDVI). Solar-induced chlorophyll fluorescence calculated at the oxygen absorption band O2-A (F760) using spectral fitting methods was also used. Simultaneously, measurements of GPP and environmental variables were conducted using a transient-state canopy chamber. Overall, GPP, F760 and VIs showed a clear seasonal time-trend in all treatments, which was driven by the phenological development of the grassland. Results showed significant differences (p<0.05) in midday GPP values between N and without N addition plots, in particular at the peak of the growing season during the flowering stage and at the end of the season during senescence. While

  14. Teaching High School Science Using Image Processing: A Case Study of Implementation of Computer Technology.

    ERIC Educational Resources Information Center

    Greenberg, Richard; Raphael, Jacqueline; Keller, Jill L.; Tobias, Sheila

    1998-01-01

    Outlines an in-depth case study of teachers' use of image processing in biology, earth science, and physics classes in one high school science department. Explores issues surrounding technology implementation. Contains 21 references. (DDR)

  15. Increasing skeletal muscle carnitine availability does not alter the adaptations to high-intensity interval training.

    PubMed

    Shannon, Christopher E; Ghasemi, Reza; Greenhaff, Paul L; Stephens, Francis B

    2017-03-27

    Increasing skeletal muscle carnitine availability alters muscle metabolism during steady-state exercise in healthy humans. We investigated whether elevating muscle carnitine, and thereby the acetyl-group buffering capacity, altered the metabolic and physiological adaptations to 24 weeks of high-intensity interval training (HIIT) at 100% maximal exercise capacity (Wattmax ). Twenty-one healthy male volunteers (age 23±2 years; BMI 24.2±1.1 kg/m(2) ) performed 2x3 minute bouts of cycling exercise at 100% Wattmax , separated by five minutes rest. Fourteen volunteers repeated this protocol following 24 weeks of HIIT and twice-daily consumption of 80g carbohydrate (CON) or 3g L-carnitine+carbohydrate (CARN). Before HIIT, muscle phosphocreatine (PCr) degradation (P<0.0001), glycogenolysis (P<0.0005), PDC activation (P<0.05), and acetylcarnitine (P<0.005) were 2.3, 2.1, 1.5 and 1.5-fold greater, respectively, in exercise bout two compared to bout one, whilst lactate accumulation tended (P<0.07) to be 1.5-fold greater. Following HIIT, muscle free carnitine was 30% greater in CARN vs CON at rest and remained 40% elevated prior to the start of bout two (P<0.05). Following bout two, free carnitine content, PCr degradation, glycogenolysis, lactate accumulation, and PDC activation were all similar between CON and CARN, albeit markedly lower than before HIIT. VO2max , Wattmax and work-output were similarly increased in CON and CARN, by 9, 15 and 23% (P<0.001). In summary, increased reliance on non-mitochondrial ATP resynthesis during a second bout of intense exercise is accompanied by increased carnitine acetylation. Augmenting muscle carnitine during 24 weeks of HIIT did not alter this, nor enhance muscle metabolic adaptations or performance gains beyond those with HIIT alone. This article is protected by copyright. All rights reserved.

  16. High-resolution prediction of soil available water content within the crop root zone

    NASA Astrophysics Data System (ADS)

    Haghverdi, Amir; Leib, Brian G.; Washington-Allen, Robert A.; Ayers, Paul D.; Buschermohle, Michael J.

    2015-11-01

    A detailed understanding of soil hydraulic properties, particularly soil available water content (AWC) within the effective root zone, is needed to optimally schedule irrigation in fields with substantial spatial heterogeneity. However, it is difficult and time consuming to directly measure soil hydraulic properties. Therefore, easily collected and measured soil properties, such as soil texture and/or bulk density, that are well correlated with hydraulic properties are used as proxies to develop pedotransfer functions (PTF). In this study, multiple modeling scenarios were developed and evaluated to indirectly predict high resolution AWC maps within the effective root zone. The modeling techniques included kriging, co-kriging, regression kriging, artificial neural networks (NN) and geographically weighted regression (GWR). The efficiency of soil apparent electrical conductivity (ECa) as proximal data in the modeling process was assessed. There was a good agreement (root mean square error (RMSE) = 0.052 cm3 cm-3 and r = 0.88) between observed and point prediction of water contents using pseudo continuous PTFs. We found that both GWR (mean RMSE = 0.062 cm3 cm-3) and regression kriging (mean RMSE = 0.063 cm3 cm-3) produced the best water content maps with these accuracies improved up to 19% when ECa was used as an ancillary soil attribute in the interpolation process. The maps indicated fourfold differences in AWC between coarse- and fine-textured soils across the study site. This provided a template for future investigations for evaluating the efficiency of variable rate irrigation management scenarios in accounting for the spatial heterogeneity of soil hydraulic attributes.

  17. An Implementation of the SNR High Speed Network Communication Protocol (Receiver Part).

    DTIC Science & Technology

    1995-03-01

    This thesis work is to implement the receiver pan of the SNR high speed network transport protocol. The approach was to use the Systems of...the SCM specification itself. The result was a correctly functioning program which implemented the SNR protocol. The system was tested using different...part of the SNR high speed transport protocol; (2) testing and integration with the transmitter part of the SNR transport protocol on an FDDI data

  18. Implementation of an Automated High-Throughput Plasmid DNA Production Pipeline.

    PubMed

    Billeci, Karen; Suh, Christopher; Di Ioia, Tina; Singh, Lovejit; Abraham, Ryan; Baldwin, Anne; Monteclaro, Stephen

    2016-12-01

    Biologics sample management facilities are often responsible for a diversity of large-molecule reagent types, such as DNA, RNAi, and protein libraries. Historically, the management of large molecules was dispersed into multiple laboratories. As methodologies to support pathway discovery, antibody discovery, and protein production have become high throughput, the implementation of automation and centralized inventory management tools has become important. To this end, to improve sample tracking, throughput, and accuracy, we have implemented a module-based automation system integrated into inventory management software using multiple platforms (Hamilton, Hudson, Dynamic Devices, and Brooks). Here we describe the implementation of these systems with a focus on high-throughput plasmid DNA production management.

  19. Implementation of a Parallel High-Performance Visualization Technique in GRASS GIS

    SciTech Connect

    Sorokine, Alexandre

    2007-01-01

    This paper describes an extension for GRASS GIS that enables users to perform geographic visualization tasks on tiled high-resolution displays powered by the clusters of commodity personal computers. Parallel visualization systems are becoming more common in scientific computing due to the decreasing hardware costs and availability of the open source software to support such architecture. High-resolution displays allow scientists to visualize very large datasets with minimal loss of details. Such systems have a big promise especially in the field of geographic information systems because users can naturally combine several geographic scales on a single display. The paper discusses architecture, implementation and operation of pd-GRASS - a GRASS GIS extension for high-performance parallel visualization on tiled displays. pd-GRASS is specifically well suited for the very large geographic datasets such as LIDAR data or high-resolution nation-wide geographic databases. The paper also briefly touches on computational efficiency, performance and potential applications for such systems.

  20. Implementing California's School Funding Formula: Will High-Need Students Benefit? Technical Appendix

    ERIC Educational Resources Information Center

    Hill, Laura; Ugo, Iwunze

    2015-01-01

    Intended to accompany "Implementing California's School Funding Formula: Will High-Need Students Benefit?," this appendix examines the extent to which school shares of high-need students vary relative to their district concentrations by grouping approximately 950 school districts by their share of high-need students, arraying them into…

  1. RELIABILITY, AVAILABILITY, AND SERVICEABILITY FOR PETASCALE HIGH-END COMPUTING AND BEYOND

    SciTech Connect

    Chokchai "Box" Leangsuksun

    2011-05-31

    Our project is a multi-institutional research effort that adopts interplay of RELIABILITY, AVAILABILITY, and SERVICEABILITY (RAS) aspects for solving resilience issues in highend scientific computing in the next generation of supercomputers. results lie in the following tracks: Failure prediction in a large scale HPC; Investigate reliability issues and mitigation techniques including in GPGPU-based HPC system; HPC resilience runtime & tools.

  2. Implementation of an Enzyme Linked Immunosorbent Assay for the Quantification of Allergenic Egg Residues in Red Wines Using Commercially Available Antibodies

    PubMed Central

    Koestel, Carole; Simonin, Céline; Belcher, Sandrine

    2016-01-01

    Abstract Since the early 2000s, labeling of potentially allergenic food components to protect people who suffer from food allergies is compulsory in numerous industrialized countries. In Europe, milk and egg components used during the winemaking process must be indicated on the label since July 1, 2012. Several ELISA procedures have been developed to detect allergenic residues in wines. However, the complexity of the wine matrix can inhibit the immunoenzymatic reaction. The aim of this study was to implement an ELISA assay for the detection of ovalbumin in red wines using commercially available antibodies. The specificity of the acquired antibodies and the absence of cross reactivity were assessed by immunoblotting and ELISA. An ELISA assay with a LOD of 14.2 μg/L and a LOQ of 56.4 μg/L of ovalbumin in aqueous solution was obtained. Differences in ELISA signals were observed when analyzing various fining agents, although reproducible conformation of the antigen could be reached for the comparison of ovalbumin and Ovicolle. The differences between samples in terms of pH could be leveled but the inhibition of the ELISA signal, positively correlated to the tannin content of the wines, could not be suppressed. Thus, standard curves of ovalbumin in several wines were obtained by relative quantification. The control steps and the difficulties encountered presented in this study should be considered by anybody working toward the development of ELISA assays for the detection of allergenic residues in complex food matrices. PMID:27356183

  3. Enterococci from Bangkok, Thailand, with high-level resistance to currently available aminoglycosides.

    PubMed Central

    Murray, B E; Tsao, J; Panida, J

    1983-01-01

    Enterococcal endocarditis is usually treated with a combination of a penicillin and an aminoglycoside. Recent reports have documented the emergence of enterococci in France with high-level resistance to gentamicin, tobramycin, and kanamycin and the emergence of strains in Houston, Tex. with high-level resistance to all of these drugs and streptomycin. In this study, we examined strains from a geographic area where newer aminoglycosides have been less commonly used. Of 125 distinct patient isolates, 18 (14%) were resistant to greater than 2,000 micrograms of gentamicin and most other aminoglycosides per ml. Four of these strains transferred gentamicin resistance to a laboratory recipient. One strain, chosen for further study, was resistant to synergism between penicillin and gentamicin, tobramycin, kanamycin, streptomycin, and amikacin and demonstrated the following enzymatic activities: 3'- and 2"-aminoglycoside phosphotransferases, 6'-aminoglycoside acetyltransferase, and adenylylation of streptomycin. Optimal therapy for endocarditis caused by such highly resistant strains is currently unknown. PMID:6614889

  4. Roadmap for High School Feedback Reports: Key Focus Areas to Ensure Quality Implementation. Data for Action

    ERIC Educational Resources Information Center

    Data Quality Campaign, 2014

    2014-01-01

    High school feedback reports let school and district leaders know where their students go after graduation and how well they are prepared for college and beyond. This roadmap discusses the seven key focus areas the Data Quality Campaign (DQC) recommends states work on to ensure quality implementation of high school feedback reports.

  5. Select Novice Elementary Teachers' Perceived Knowledge and Implementation of High-Quality Reading Instruction

    ERIC Educational Resources Information Center

    Bumstead, Stacey

    2012-01-01

    The purpose of this mixed methods study was to examine select novice teachers' perceived knowledge of high-quality reading instruction, explore the extent that select novice teachers implemented high-quality reading instruction into their own classrooms, and to investigate any factors that explain the similarities and differences between…

  6. Preparing for High Technology: 30 Steps to Implementation. Research & Development Series No. 232.

    ERIC Educational Resources Information Center

    Abram, Robert; And Others

    This planning guide is one of three that addresses the concerns of postsecondary college administrators and planners regarding the planning and implementation of technician training programs in high technology areas. It specifically focuses on a 30-step planning process that is generalizable to various high technology areas. (The other two…

  7. Preparing Students for College: The Implementation and Impact of the Early College High School Model

    ERIC Educational Resources Information Center

    Edmunds, Julie A.; Bernstein, Lawrence; Glennie, Elizabeth; Willse, John; Arshavsky, Nina; Unlu, Fatih; Bartz, Deborah; Silberman, Todd; Scales, W. David; Dallas, Andrew

    2010-01-01

    As implemented in North Carolina, Early College High Schools are small, autonomous schools designed to increase the number of students who graduate from high school and are prepared for postsecondary education. Targeted at students who are underrepresented in college, these schools are most frequently located on college campuses and are intended…

  8. Mandated Site-Based Management in Texas: Exploring Implementation in Urban High Schools.

    ERIC Educational Resources Information Center

    Kemper, Elizabeth A.; Teddlie, Charles

    2000-01-01

    Examined implementation of state-mandated site-based management (SBM) in Texas high schools. Teacher and principal surveys indicated that state-level reform policies were subject to interpretation at the school level. Urban schools had high levels of SBM program structure but low teacher perceptions of decision making responsibility. Case studies…

  9. RF/optical shared aperture for high availability wideband communication RF/FSO links

    DOEpatents

    Ruggiero, Anthony J; Pao, Hsueh-yuan; Sargis, Paul

    2015-03-24

    An RF/Optical shared aperture is capable of transmitting and receiving optical signals and RF signals simultaneously. This technology enables compact wide bandwidth communications systems with 100% availability in clear air turbulence, rain and fog. The functions of an optical telescope and an RF reflector antenna are combined into a single compact package by installing an RF feed at either of the focal points of a modified Gregorian telescope.

  10. RF/optical shared aperture for high availability wideband communication RF/FSO links

    DOEpatents

    Ruggiero, Anthony J; Pao, Hsueh-yuan; Sargis, Paul

    2014-04-29

    An RF/Optical shared aperture is capable of transmitting and receiving optical signals and RF signals simultaneously. This technology enables compact wide bandwidth communications systems with 100% availability in clear air turbulence, rain and fog. The functions of an optical telescope and an RF reflector antenna are combined into a single compact package by installing an RF feed at either of the focal points of a modified Gregorian telescope.

  11. Systematic review of available evidence on 11 high-priced inpatient orphan drugs

    PubMed Central

    2013-01-01

    Background Attention for Evidence Based Medicine (EBM) is growing, but evidence for orphan drugs is argued to be limited and inferior. This study systematically reviews the available evidence on clinical effectiveness, cost-effectiveness and budget impact for orphan drugs. Methods A systematic review was performed in PubMed, Embase, NHS EED and HTA databases for 11 inpatient orphan drugs listed on the Dutch policy rule on orphan drugs. For included studies, we determined the type of study and various study characteristics. Results A total of 338 studies met all inclusion criteria. Almost all studies (96%) focused on clinical effectiveness of the drug. Of these studies, most studies were case studies (41%) or observational studies (39%). However, for all orphan diseases at least one experimental or quasi-experimental study was found, and a randomized clinical trial was available for 60% of the orphan drugs. Eight studies described the cost-effectiveness of an orphan drug; an equal number described an orphan drug’s budget impact. Conclusions Despite the often heard claim that RCTs are not feasible for orphan drugs, we found that an RCT was available in 60% of orphan drugs investigated. Cost-effectiveness and budget impact analyses for orphan drugs are seldom published. PMID:23947946

  12. The Availability and Delivery of Health Care to High School Athletes in Alabama.

    ERIC Educational Resources Information Center

    Culpepper, Michael I.

    1986-01-01

    A sports medicine survey of 119 public high schools in Alabama showed smaller schools at a disadvantage in offering health care for athletes relative to larger schools. Many schools rated the delivery and quality of medical care to the athletes as fair to very poor. (MT)

  13. Investigating Commercially Available Technology for Language Learners in Higher Education within the High Functioning Disability Spectrum

    ERIC Educational Resources Information Center

    Savvidou, Georgia; Loizides, Fernando

    2016-01-01

    This work presents the assistive use of a combination of technologies in language learning to individuals with high functioning disabilities within a higher education environment. The primary aim of this research is to introduce the initial findings of a pilot exploratory user test which aims to facilitate a better understanding of the suitability…

  14. A Comparison of the High Count Rate Performance of Three Commercially Available Digital Signal Processors

    SciTech Connect

    Dawn M. Scates; John K. Hartwell

    2005-10-01

    Three commercial ã-ray digital signal processors, a Canberra InSpector 2000, an ORTEC DigiDART, and an X-ray Instrumentation Associates Polaris system, coupled to a Canberra 2002C resistive-feedback preamplifier-equipped high-purity germanium detector, were performance tested to input rates of 440 kHz. The spectrometers were evaluated on their throughput, stability and peak shape performance. The accuracy of their quantitative corrections for dead time and pile-up were also tested. All three of the tested units performed well at input rates that strain most analog spectroscopy systems.

  15. Future water availability in North African dams simulated by high-resolution regional climate models

    NASA Astrophysics Data System (ADS)

    Tramblay, Yves; Jarlan, Lionel; Hanich, Lahoucine; Somot, Samuel

    2016-04-01

    In North Africa, the countries of Morocco, Algeria and Tunisia are already experiencing water scarcity and a strong interannual variability of precipitation. To better manage their existing water resources, several dams and reservoirs have been built on most large river catchments. The objective of this study is to provide quantitative scenarios of future changes in water availability for the 47 major dams and reservoirs catchments located in North Africa. An ensemble of regional climate models (RCM) with a spatial resolution of 12km, driven by different general circulation models (GCM), from the EuroCORDEX experiment have been considered to analyze the projected changes on temperature, precipitation and potential evapotranspiration (PET) for two scenarios (RCP4.5 and RCP8.5) and two time horizons (2040-2065 and 2065-2090). PET is estimated from RCM outputs either with the FAO-Penman-Monteith (PM) equation, requiring air temperature, relative humidity, net radiation and wind, or with the Hargreave Samani (HS) equation, requiring only air temperature. The water balance is analyzed by comparing the climatic demand and supply of water, considering that for most of these catchments groundwater storage is negligible over long time periods. Results indicated a future temperature increase for all catchments between +1.8° and +4.2°, depending on the emission scenario and the time period considered. Precipitation is projected to decrease between -14% to -27%, mainly in winter and spring, with a strong East to West gradient. PET computed from PM or HS formulas provided very similar estimates and projections, ranging between +7% to +18%. Changes in PET are mostly driven by rising temperatures and are greatest during dry summer months than for the wet winter season. Therefore the increased PET has a lower impact than declining precipitation on future water availability, which is expected to decrease by -19% to -33% on average.

  16. Fish bones--a highly available calcium source for growing pigs.

    PubMed

    Malde, M K; Graff, I E; Siljander-Rasi, H; Venäläinen, E; Julshamn, K; Pedersen, J I; Valaja, J

    2010-10-01

    In general, there is a lack of scientific documentation of nutritional value of marine by-products. The bone fraction from fish has been regarded as waste. Due to the high mineral content of fish bones, this material can be well suitable as a natural calcium source. In the present study, apparent calcium absorption of different fish bone sources was tested using growing pigs. The experimental diets consisted of boiled salmon frames, or salmon, saithe or cod bones treated with enzymes. Calcium carbonate (CaCO(3)) was used as control. The experimental diets were formulated to contain 0.7% total calcium of which the added calcium source to be tested contributed about 71% (study 1) and 86% (study 2). Except for the calcium and phosphorus sources, the animals received similar basal diets. Apparent calcium digestibility coefficient was calculated using yttrium as indicator (both studies) and was based on complete collection of faeces and urine (study 2). The experimental design was parallel and cross-over in study 1 and study 2, respectively. In study 1, piglets getting salmon bone treated with enzymes had significantly higher calcium absorption than piglets getting boiled fish bone or calcium carbonate. Therefore, in the second study only enzymatically treated fish bones were included. The higher calcium absorption from enzymatically treated salmon bone was also found in study 2, but this time not significant. Calcium from boiled salmon bones in study I, and from enzymatically treated saithe and cod bones in study II were absorbed as well as the calcium carbonate control. The results indicate that fish bones may be a useful and well absorbed calcium source. Due to the high mineral content of the bone fraction, salmon bones can be well suitable as a natural calcium and phosphorus source in, for example, food, feed or as supplement.

  17. High-glycaemic index and -glycaemic load meals increase the availability of tryptophan in healthy volunteers.

    PubMed

    Herrera, Christopher P; Smith, Keir; Atkinson, Fiona; Ruell, Patricia; Chow, Chin Moi; O'Connor, Helen; Brand-Miller, Jennie

    2011-06-01

    The purpose of the present study was to determine the influence of the glycaemic index (GI) and glycaemic load (GL) on the ratio of tryptophan (TRP) relative to other large neutral amino acids (LNAA). Ten healthy men (age 22·9 (sd 3·4) years; BMI 23·5 (sd 1·6) kg/m2) underwent standard GI testing, and later consumed each of a mixed-macronutrient (1915 kJ; 66·5 % carbohydrate (CHO), 17 % protein and 16·5 % fat) high-GI (MHGI), an isoenergetic, mixed-macronutrient low-GI (MLGI) and a CHO-only (3212 kJ; 90 % CHO, 8 % protein, 2 % fat) high-GI (CHGI) meal on separate days. The GI, GL and insulin index values (e.g. area under the curve) were largest after the CHGI meal (117, 200, 158), followed by the MHGI (79, 59, 82) and MLGI (51, 38, 56) meals, respectively (all values were significantly different, P < 0·05). After the MHGI and MLGI meals but not after the CHGI meal, TRP was elevated at 120 and 180 min (P < 0·05). After the CHGI, LNAA was lower compared with the MLGI (P < 0·05); also the rate of decline in LNAA was higher after CHGI compared with MHGI and MLGI (both comparisons P < 0·05). The percentage increase from baseline in TRP:LNAA after CHGI (23 %) was only marginally higher than after the MHGI meal (17 %; P = 0·38), but it was threefold and nearly significantly greater than MLGI (8 %; P = 0·05). The present study demonstrates that the postprandial rise in TRP:LNAA was increased by additional CHO ingestion and higher GI. Therefore, the meal GL appears to be an important factor influencing the postprandial TRP:LNAA concentration.

  18. Making resonance a common case: a high-performance implementation of collective I/O on parallel file systems

    SciTech Connect

    Davis, Marion Kei; Zhang, Xuechen; Jiang, Song

    2009-01-01

    Collective I/O is a widely used technique to improve I/O performance in parallel computing. It can be implemented as a client-based or server-based scheme. The client-based implementation is more widely adopted in MPI-IO software such as ROMIO because of its independence from the storage system configuration and its greater portability. However, existing implementations of client-side collective I/O do not take into account the actual pattern offile striping over multiple I/O nodes in the storage system. This can cause a significant number of requests for non-sequential data at I/O nodes, substantially degrading I/O performance. Investigating the surprisingly high I/O throughput achieved when there is an accidental match between a particular request pattern and the data striping pattern on the I/O nodes, we reveal the resonance phenomenon as the cause. Exploiting readily available information on data striping from the metadata server in popular file systems such as PVFS2 and Lustre, we design a new collective I/O implementation technique, resonant I/O, that makes resonance a common case. Resonant I/O rearranges requests from multiple MPI processes to transform non-sequential data accesses on I/O nodes into sequential accesses, significantly improving I/O performance without compromising the independence ofa client-based implementation. We have implemented our design in ROMIO. Our experimental results show that the scheme can increase I/O throughput for some commonly used parallel I/O benchmarks such as mpi-io-test and ior-mpi-io over the existing implementation of ROMIO by up to 157%, with no scenario demonstrating significantly decreased performance.

  19. Using DNA metabarcoding to investigate honey bee foraging reveals limited flower use despite high floral availability

    PubMed Central

    de Vere, Natasha; Jones, Laura E.; Gilmore, Tegan; Moscrop, Jake; Lowe, Abigail; Smith, Dan; Hegarty, Matthew J.; Creer, Simon; Ford, Col R.

    2017-01-01

    Understanding which flowers honey bees (Apis mellifera) use for forage can help us to provide suitable plants for healthy honey bee colonies. Accordingly, honey DNA metabarcoding provides a valuable tool for investigating pollen and nectar collection. We investigated early season (April and May) floral choice by honey bees provided with a very high diversity of flowering plants within the National Botanic Garden of Wales. There was a close correspondence between the phenology of flowering and the detection of plants within the honey. Within the study area there were 437 genera of plants in flower during April and May, but only 11% of these were used. Thirty-nine plant taxa were recorded from three hives but only ten at greater than 1%. All three colonies used the same core set of native or near-native plants, typically found in hedgerows and woodlands. The major plants were supplemented with a range of horticultural species, with more variation in plant choice between the honey bee colonies. We conclude that during the spring, honey bees need access to native hedgerows and woodlands to provide major plants for foraging. Gardens provide supplementary flowers that may increase the nutritional diversity of the honey bee diet. PMID:28205632

  20. Detection of high-risk human papillomavirus infection in tonsillar specimens using 2 commercially available assays.

    PubMed

    Cockerill, Cara C; Orvidas, Laura J; Moore, Eric J; Binnicker, Matthew J; Duresko, Brian J; Espy, Mark J; Cockerill, Franklin R; Tombers, Nicole M; Pritt, Bobbi S

    2016-12-01

    THE OBJECTIVE OF THE STUDY IS TO DETERMINE THE PREVALENCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS (HRHPV) INFECTION IN TONSILLAR SWABS AND TISSUE: Patients undergoing tonsillectomy for nonmalignant causes were enrolled. A flocked swab and fresh tissue were collected from the left and right tonsil of each patient. Specimens were tested for hrHPV DNA using the Roche cobas test and for the presence of E6/E7 messenger RNA using the Hologic Aptima hrHPV test. Of the 193 patients enrolled, 129 were in the pediatric group (ages 1-12years; median, 5years), and 64 were in the adult group (ages 13-55; median, 22years). All swab and tissue specimens were negative for hrHPV by both methods. Positive, negative, and internal controls performed as expected. We found a 0% rate of infection indicating that detectable hrHPV infection in tonsillar tissue appears to be uncommon in the children and adults in the population sampled.

  1. Using DNA metabarcoding to investigate honey bee foraging reveals limited flower use despite high floral availability.

    PubMed

    de Vere, Natasha; Jones, Laura E; Gilmore, Tegan; Moscrop, Jake; Lowe, Abigail; Smith, Dan; Hegarty, Matthew J; Creer, Simon; Ford, Col R

    2017-02-16

    Understanding which flowers honey bees (Apis mellifera) use for forage can help us to provide suitable plants for healthy honey bee colonies. Accordingly, honey DNA metabarcoding provides a valuable tool for investigating pollen and nectar collection. We investigated early season (April and May) floral choice by honey bees provided with a very high diversity of flowering plants within the National Botanic Garden of Wales. There was a close correspondence between the phenology of flowering and the detection of plants within the honey. Within the study area there were 437 genera of plants in flower during April and May, but only 11% of these were used. Thirty-nine plant taxa were recorded from three hives but only ten at greater than 1%. All three colonies used the same core set of native or near-native plants, typically found in hedgerows and woodlands. The major plants were supplemented with a range of horticultural species, with more variation in plant choice between the honey bee colonies. We conclude that during the spring, honey bees need access to native hedgerows and woodlands to provide major plants for foraging. Gardens provide supplementary flowers that may increase the nutritional diversity of the honey bee diet.

  2. NOAA Operational Model Archive Distribution System (NOMADS): High Availability Applications for Reliable Real Time Access to Operational Model Data

    NASA Astrophysics Data System (ADS)

    Alpert, J. C.; Wang, J.

    2009-12-01

    To reduce the impact of natural hazards and environmental changes, the National Centers for Environmental Prediction (NCEP) provide first alert and a preferred partner for environmental prediction services, and represents a critical national resource to operational and research communities affected by climate, weather and water. NOMADS is now delivering high availability services as part of NOAA’s official real time data dissemination at its Web Operations Center (WOC) server. The WOC is a web service used by organizational units in and outside NOAA, and acts as a data repository where public information can be posted to a secure and scalable content server. A goal is to foster collaborations among the research and education communities, value added retailers, and public access for science and development efforts aimed at advancing modeling and GEO-related tasks. The user (client) executes what is efficient to execute on the client and the server efficiently provides format independent access services. Client applications can execute on the server, if it is desired, but the same program can be executed on the client side with no loss of efficiency. In this way this paradigm lends itself to aggregation servers that act as servers of servers listing, searching catalogs of holdings, data mining, and updating information from the metadata descriptions that enable collections of data in disparate places to be simultaneously accessed, with results processed on servers and clients to produce a needed answer. The services used to access the operational model data output are the Open-source Project for a Network Data Access Protocol (OPeNDAP), implemented with the Grid Analysis and Display System (GrADS) Data Server (GDS), and applications for slicing, dicing and area sub-setting the large matrix of real time model data holdings. This approach insures an efficient use of computer resources because users transmit/receive only the data necessary for their tasks including

  3. System, apparatus and methods to implement high-speed network analyzers

    DOEpatents

    Ezick, James; Lethin, Richard; Ros-Giralt, Jordi; Szilagyi, Peter; Wohlford, David E

    2015-11-10

    Systems, apparatus and methods for the implementation of high-speed network analyzers are provided. A set of high-level specifications is used to define the behavior of the network analyzer emitted by a compiler. An optimized inline workflow to process regular expressions is presented without sacrificing the semantic capabilities of the processing engine. An optimized packet dispatcher implements a subset of the functions implemented by the network analyzer, providing a fast and slow path workflow used to accelerate specific processing units. Such dispatcher facility can also be used as a cache of policies, wherein if a policy is found, then packet manipulations associated with the policy can be quickly performed. An optimized method of generating DFA specifications for network signatures is also presented. The method accepts several optimization criteria, such as min-max allocations or optimal allocations based on the probability of occurrence of each signature input bit.

  4. Implementation of checklists in health care; learning from high-reliability organisations

    PubMed Central

    2011-01-01

    Background Checklists are common in some medical fields, including surgery, intensive care and emergency medicine. They can be an effective tool to improve care processes and reduce mortality and morbidity. Despite the seemingly rapid acceptance and dissemination of the checklist, there are few studies describing the actual process of developing and implementing such tools in health care. The aim of this study is to explore the experiences from checklist development and implementation in a group of non-medical, high reliability organisations (HROs). Method A qualitative study based on key informant interviews and field visits followed by a Delphi approach. Eight informants, each with 10-30 years of checklist experience, were recruited from six different HROs. Results The interviews generated 84 assertions and recommendations for checklist implementation. To achieve checklist acceptance and compliance, there must be a predefined need for which a checklist is considered a well suited solution. The end-users ("sharp-end") are the key stakeholders throughout the development and implementation process. Proximity and ownership must be assured through a thorough and wise process. All informants underlined the importance of short, self-developed, and operationally-suited checklists. Simulation is a valuable and widely used method for training, revision, and validation. Conclusion Checklists have been a cornerstone of safety management in HROs for nearly a century, and are becoming increasingly popular in medicine. Acceptance and compliance are crucial for checklist implementation in health care. Experiences from HROs may provide valuable input to checklist implementation in healthcare. PMID:21967747

  5. Designing and implementing Multibeam Smart Antennas for high bandwidth UAV communications using FPGAs

    NASA Astrophysics Data System (ADS)

    Porcello, J. C.

    Requirements for high bandwidth UAV communications are often necessary in order to move large amounts of mission information to/from Users in real-time. The focus of this paper is antenna beamforming for point-to-point, high bandwidth UAV communications in order to optimize transmit and receive power and support high data throughput communications. Specifically, this paper looks at the design and implementation of Multibeam Smart Antennas to implement antenna beamforming in an aerospace communications environment. The Smart Antenna is contrasted against Fast Fourier Transform (FFT) based beamforming in order to quantify the increase in both computational load and FPGA resources required for multibeam adaptive signal processing in the Smart Antenna. The paper begins with an overall discussion of Smart Antenna design and general beamforming issues in high bandwidth communications. Important design considerations such as processing complexity in a constrained Size, Weight and Power (SWaP) environment are discussed. The focus of the paper is with respect to design and implementation of digital beamforming wideband communications waveforms using FPGAs. A Multibeam Time Delay element is introduced based on Lagrange Interpolation. Design data for Multibeam Smart Antennas in FPGAs is provided in the paper as well as reference circuits for implementation. Finally, an example Multibeam Smart Antenna design is provided based on a Xilinx Virtex-7 FPGA. The Multibeam Smart Antenna example design illustrates the concepts discussed in the paper and provides design insight into Multibeam Smart Antenna implementation from the point of view of implementation complexity, required hardware, and overall system performance gain.

  6. 76 FR 14025 - Guidance for Industry on Planning for the Effects of High Absenteeism To Ensure Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Planning for the Effects of High Absenteeism To Ensure Availability of Medically Necessary Drug Products; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing...

  7. Highly Proficient Bilinguals Implement Inhibition: Evidence from N-2 Language Repetition Costs

    ERIC Educational Resources Information Center

    Declerck, Mathieu; Thoma, Aniella M.; Koch, Iring; Philipp, Andrea M.

    2015-01-01

    Several, but not all, models of language control assume that highly proficient bilinguals implement little to no inhibition during bilingual language production. In the current study, we tested this assumption with a less equivocal marker of inhibition (i.e., n-2 language repetition costs) than previous language switching studies have. N-2…

  8. An Examination of University Agricultural Education Faculty Attitudes toward the Implementation of High Impact Learning Experiences

    ERIC Educational Resources Information Center

    Murphrey, Theresa Pesl; Odom, Summer F.; Sledd, James

    2016-01-01

    Meaningful learning is a goal across the broad field of agricultural education and high impact learning (HIL) experiences are a mechanism to facilitate that goal. The purpose of this study was to examine university agricultural education faculty attitudes toward the implementation of HIL. Faculty (n=85) from 10 agricultural education departments…

  9. It Takes a Network: One Curriculum Leader Implements the Common Core High School Mathematics Standards

    ERIC Educational Resources Information Center

    Beckford, Franchetta Joenise

    2013-01-01

    This qualitative study was conducted for the purpose of determining whether a district mathematics curriculum leader's social network advanced the implementation of the high school mathematics Common Core State Standards (CCSS) (CCSSI, 2012c). The qualitative data was collected through an interview, a hand-drawn network map, observations, and…

  10. A Systematic Approach to Improving E-Learning Implementations in High Schools

    ERIC Educational Resources Information Center

    Pardamean, Bens; Suparyanto, Teddy

    2014-01-01

    This study was based on the current growing trend of implementing e-learning in high schools. Most endeavors have been inefficient, rendering an objective of determining the initial steps that could be taken to improve these efforts by assessing a student population's computer skill levels and performances in an IT course. Demographic factors were…

  11. High-Capacity Photorefractive Neural Network Implementing a Kohonen Topological Map

    NASA Astrophysics Data System (ADS)

    Frauel, Yann; Pauliat, Gilles; Villing, André; Roosen, Gérald

    2001-10-01

    We designed and built a high-capacity neural network based on volume holographic interconnections in a photorefractive crystal. We used this system to implement a Kohonen topological map. We describe and justify our optical setup and present some experimental results of self-organization in the learning database.

  12. Implementing Student Information Systems in High Schools: An Embedded Single Case Study

    ERIC Educational Resources Information Center

    Rhodes-O'Neill, Tamyra LaShawn

    2014-01-01

    As new technologies are developed for teaching and learning, they hold the potential to transform education but have yet to be fully integrated into K-12 classrooms in the United States. The purpose of this study was to explore how a student information system was implemented in 2 urban public high schools and how stakeholders perceived that…

  13. The Three-Block Model of Universal Design for Learning Implementation in a High School

    ERIC Educational Resources Information Center

    Katz, Jennifer; Sugden, Ron

    2013-01-01

    The role of the school leader (principal) in supporting educational reform is explored through a case study of one high school implementing the Three Block Model of UDL (Katz, 2012a) in an effort to meet the needs of a diverse student population. This case study is a part of a much larger study exploring outcomes for students and teachers of…

  14. Implementation of Formative Assessment Strategies as Perceived by High School Students and Teachers: Professional Development Implications

    ERIC Educational Resources Information Center

    Burns, Rosemary

    2010-01-01

    The purpose of this research study was to investigate the level of implementation of formative assessment strategies among Rhode Island high school teachers and students in three districts. Furthermore, the research analyzed the relationship of the disciplines taught, the amount and kinds of professional development teachers had, and district…

  15. Implementation of an Entry-Level Retention Program for High-Risk College Freshmen.

    ERIC Educational Resources Information Center

    Zanoni, Candido

    The specially funded program described in this report was implemented at the University of Minnesota's General College in Fall 1979 to promote the academic improvement and long-range retention of high-risk Black, Hispanic, and Native American students. After introductory material discussing the process involved in securing program funds from the…

  16. Academic-Career Integration in Magnet High Schools: Assessing the Level of Implementation.

    ERIC Educational Resources Information Center

    Tokarska, Barbara; And Others

    An ongoing study examined implementation and student response to academic career magnet (ACM) programs in New York City high schools. The programs emphasize both college preparation and career education, demonstrating one approach to the current emphasis on integrating academic and vocational education. New York City offers a wide array of magnet…

  17. Implementing a Project-Based Technology Program for High School Women.

    ERIC Educational Resources Information Center

    Boudria, Theodore J.

    2002-01-01

    Describes the successful implementation of a Women in Technology (WIT) Project-Based Learning Program in High Tech Manufacturing by the Tech Prep Consortium at Bristol Community College (Massachusetts). Reports that the program's success was mainly due to the establishment of partnerships with industry, government, and education, including area…

  18. A Literature Review: The Effect of Implementing Technology in a High School Mathematics Classroom

    ERIC Educational Resources Information Center

    Murphy, Daniel

    2016-01-01

    This study is a literature review to investigate the effects of implementing technology into a high school mathematics classroom. Mathematics has a hierarchical structure in learning and it is essential that students get a firm understanding of mathematics early in education. Some students that miss beginning concepts may continue to struggle with…

  19. Implementing a Highly Specified Curricular, Instructional, and Organizational School Design in a High-Poverty Urban Elementary School: Three Year Results. Report No. 20.

    ERIC Educational Resources Information Center

    McHugh, Barbara; Stringfield, Sam

    This report provides background, implementation, and diverse outcome data from the first 3 years of an ongoing effort to implement a highly specified school reform design in a high-poverty, urban elementary school, Woodson Elementary School, Baltimore (Maryland). The design that is being implemented is the Calvert School model. The Calvert School…

  20. High-frequency, high-sensitivity acoustic sensor implemented on ALN/Si substrate

    NASA Astrophysics Data System (ADS)

    Caliendo, C.; Imperatori, P.

    2003-08-01

    AlN films, 1.6-6.3 μm thick, were sputtered at 200 °C on Si(100) and Si(111) substrates. The films were crack-free, uniform, and c-axis oriented. The experimental phase velocities of surface acoustic waves (SAW) propagating in the AlN/Si structures were estimated and showed only a small discrepancy (20-40 m/s) compared to the calculated theoretical values. A SAW resonator (SAWR)-based chemical sensor, operating at about 700 MHz, was implemented on AlN/Si. The SAWR surface was covered with a polymer film sensitive to relative humidity (RH) changes, already tested for RH sensing in previous works on SAW delay lines implemented on AlN/Si and ZnO/Si and operating at about 130 MHz. The RH mass sensitivity and the detection limit of the SAWR sensor improved by 38% and by one order of magnitude, respectively, compared to the delay line-based sensors previously tested.

  1. Implementation of scalable video coding deblocking filter from high-level SystemC description

    NASA Astrophysics Data System (ADS)

    Carballo, Pedro P.; Espino, Omar; Neris, Romén.; Hernández-Fernández, Pedro; Szydzik, Tomasz M.; Núñez, Antonio

    2013-05-01

    This paper describes key concepts in the design and implementation of a deblocking filter (DF) for a H.264/SVC video decoder. The DF supports QCIF and CIF video formats with temporal and spatial scalability. The design flow starts from a SystemC functional model and has been refined using high-level synthesis methodology to RTL microarchitecture. The process is guided with performance measurements (latency, cycle time, power, resource utilization) with the objective of assuring the quality of results of the final system. The functional model of the DF is created in an incremental way from the AVC DF model using OpenSVC source code as reference. The design flow continues with the logic synthesis and the implementation on the FPGA using various strategies. The final implementation is chosen among the implementations that meet the timing constraints. The DF is capable to run at 100 MHz, and macroblocks are processed in 6,500 clock cycles for a throughput of 130 fps for QCIF format and 37 fps for CIF format. The proposed architecture for the complete H.264/SVC decoder is composed of an OMAP 3530 SOC (ARM Cortex-A8 GPP + DSP) and the FPGA Virtex-5 acting as a coprocessor for DF implementation. The DF is connected to the OMAP SOC using the GPMC interface. A validation platform has been developed using the embedded PowerPC processor in the FPGA, composing a SoC that integrates the frame generation and visualization in a TFT screen. The FPGA implements both the DF core and a GPMC slave core. Both cores are connected to the PowerPC440 embedded processor using LocalLink interfaces. The FPGA also contains a local memory capable of storing information necessary to filter a complete frame and to store a decoded picture frame. The complete system is implemented in a Virtex5 FX70T device.

  2. Implementation of physics and everyday thinking in a high school classroom: Concepts and argumentation

    NASA Astrophysics Data System (ADS)

    Belleau, Shelly N.; Ross, Mike J.; Otero, Valerie K.

    2012-02-01

    The Physics and Everyday Thinking (PET) curriculum is based on educational research and consists of carefully sequenced sets of activities intended to help students develop physics ideas through guided experimentation and questioning with extensive small group and whole class discussion. A high school physics teacher has adapted and implemented the PET curriculum in a low-income urban high school with the aim of removing barriers that typically limit access to traditional physics curriculum. Though PET was not designed for secondary physics students, this teacher has worked closely with physics education research faculty and graduate students to simultaneously modify, implement, and investigate the impact of PET on urban high school students' physics learning. Preliminary results indicate that the PET curriculum has great potential to provide students with opportunities for success in understanding physics concepts, as well as helping to develop scientific argumentation strategies.

  3. Scalable Unix commands for parallel processors : a high-performance implementation.

    SciTech Connect

    Ong, E.; Lusk, E.; Gropp, W.

    2001-06-22

    We describe a family of MPI applications we call the Parallel Unix Commands. These commands are natural parallel versions of common Unix user commands such as ls, ps, and find, together with a few similar commands particular to the parallel environment. We describe the design and implementation of these programs and present some performance results on a 256-node Linux cluster. The Parallel Unix Commands are open source and freely available.

  4. Implementing Molecular Dynamics on Hybrid High Performance Computers - Particle-Particle Particle-Mesh

    SciTech Connect

    Brown, W Michael; Kohlmeyer, Axel; Plimpton, Steven J; Tharrington, Arnold N

    2012-01-01

    The use of accelerators such as graphics processing units (GPUs) has become popular in scientific computing applications due to their low cost, impressive floating-point capabilities, high memory bandwidth, and low electrical power requirements. Hybrid high-performance computers, machines with nodes containing more than one type of floating-point processor (e.g. CPU and GPU), are now becoming more prevalent due to these advantages. In this paper, we present a continuation of previous work implementing algorithms for using accelerators into the LAMMPS molecular dynamics software for distributed memory parallel hybrid machines. In our previous work, we focused on acceleration for short-range models with an approach intended to harness the processing power of both the accelerator and (multi-core) CPUs. To augment the existing implementations, we present an efficient implementation of long-range electrostatic force calculation for molecular dynamics. Specifically, we present an implementation of the particle-particle particle-mesh method based on the work by Harvey and De Fabritiis. We present benchmark results on the Keeneland InfiniBand GPU cluster. We provide a performance comparison of the same kernels compiled with both CUDA and OpenCL. We discuss limitations to parallel efficiency and future directions for improving performance on hybrid or heterogeneous computers.

  5. Design and implementation of interface units for high speed fiber optics local area networks and broadband integrated services digital networks

    NASA Technical Reports Server (NTRS)

    Tobagi, Fouad A.; Dalgic, Ismail; Pang, Joseph

    1990-01-01

    The design and implementation of interface units for high speed Fiber Optic Local Area Networks and Broadband Integrated Services Digital Networks are discussed. During the last years, a number of network adapters that are designed to support high speed communications have emerged. This approach to the design of a high speed network interface unit was to implement package processing functions in hardware, using VLSI technology. The VLSI hardware implementation of a buffer management unit, which is required in such architectures, is described.

  6. Development and implementation of industrialized, fully automated high throughput screening systems

    PubMed Central

    2003-01-01

    Automation has long been a resource for high-throughput screening at Bristol-Myers Squibb. However, with growing deck sizes and decreasing time lines, a new generation of more robust, supportable automated systems was necessary for accomplishing high-throughput screening goals. Implementation of this new generation of automated systems required numerous decisions concerning hardware, software and the value of in-house automation expertise. This project has resulted in fast, flexible, industrialized automation systems with a strong in-house support structure that we believe meets our current high-throughput screening requirements and will continue to meet them well into the future. PMID:18924614

  7. A C++11 implementation of arbitrary-rank tensors for high-performance computing

    NASA Astrophysics Data System (ADS)

    Aragón, Alejandro M.

    2014-06-01

    This article discusses an efficient implementation of tensors of arbitrary rank by using some of the idioms introduced by the recently published C++ ISO Standard (C++11). With the aims at providing a basic building block for high-performance computing, a single Array class template is carefully crafted, from which vectors, matrices, and even higher-order tensors can be created. An expression template facility is also built around the array class template to provide convenient mathematical syntax. As a result, by using templates, an extra high-level layer is added to the C++ language when dealing with algebraic objects and their operations, without compromising performance. The implementation is tested running on both CPU and GPU.

  8. Implementation and Evaluation 
of a High-Dose Cytarabine Neurologic Assessment Tool.

    PubMed

    Szoch, Stephanie; Snow Kaiser, Karen

    2015-06-01

    Patients receiving high-dose cytarabine as part of their chemotherapy regimen have a chance of experiencing neurotoxicities. Prompt identification of signs and symptoms can greatly reduce the chance of patients sustaining permanent neurologic damage. This article describes the development and successful implementation of an evidence-based, standardized neurologic assessment and documentation tool that was evaluated using a clinical utility questionnaire and an adherence audit.

  9. Parallel Implementation of a High Order Implicit Collocation Method for the Heat Equation

    NASA Technical Reports Server (NTRS)

    Kouatchou, Jules; Halem, Milton (Technical Monitor)

    2000-01-01

    We combine a high order compact finite difference approximation and collocation techniques to numerically solve the two dimensional heat equation. The resulting method is implicit arid can be parallelized with a strategy that allows parallelization across both time and space. We compare the parallel implementation of the new method with a classical implicit method, namely the Crank-Nicolson method, where the parallelization is done across space only. Numerical experiments are carried out on the SGI Origin 2000.

  10. Computer simulations in teaching physics: Development and implementation of a hypermedia system for high school teachers

    NASA Astrophysics Data System (ADS)

    da Silva, A. M. R.; de Macêdo, J. A.

    2016-06-01

    On the basis of the technological advancement in the middle and the difficulty of learning by the students in the discipline of physics, this article describes the process of elaboration and implementation of a hypermedia system for high school teachers involving computer simulations for teaching basic concepts of electromagnetism, using free tool. With the completion and publication of the project there will be a new possibility of interaction of students and teachers with the technology in the classroom and in labs.

  11. Implementing high-fidelity simulations with large groups of nursing students.

    PubMed

    Hooper, Barbara; Shaw, Luanne; Zamzam, Rebekah

    2015-01-01

    Nurse educators are increasing the use of simulation as a teaching strategy. Simulations are conducted typically with a small group of students. This article describes the process for implementing 6 high-fidelity simulations with a large group of undergraduate nursing students. The goal was to evaluate if student knowledge increased on postsimulation quiz scores when only a few individuals actively participated in the simulation while the other students observed.

  12. Implementation of High Dimensional Feature Map for Segmentation of MR Images

    PubMed Central

    He, Renjie; Sajja, Balasrinivasa Rao; Narayana, Ponnada A.

    2005-01-01

    A method that considerably reduces the computational and memory complexities associated with the generation of high dimensional (≥3) feature maps for image segmentation is described. The method is based on the K-nearest neighbor (KNN) classification and consists of two parts: preprocessing of feature space and fast KNN. This technique is implemented on a PC and applied for generating three-and four-dimensional feature maps for segmenting MR brain images of multiple sclerosis patients. PMID:16240091

  13. Great Careers in Two Years: The Associate Degree Option. High Skill and High Wage Jobs Available through Two-Year Programs.

    ERIC Educational Resources Information Center

    Phifer, Paul

    This book explores high-skill and high-wage jobs available through two-year programs. It identifies 100 high-need occupational areas, and discusses "hot" programs and starting salaries for graduates of dental hygiene, manufacturing, process technology, telecommunications, physical therapy assisting, and registered nursing. Each career article…

  14. An Exploration of Support Factors Available to Higher Education Students with High Functioning Autism or Asperger Syndrome

    ERIC Educational Resources Information Center

    Rutherford, Emily N.

    2013-01-01

    This qualitative phenomenological research study used narrative inquiry to explore the support factors available to students with High Functioning Autism or Asperger Syndrome in higher education that contribute to their success as perceived by the students. Creswell's (2009) six step method for analyzing phenomenological studies was used to…

  15. 77 FR 64183 - Notice of Availability of a Final General Conformity Determination for the California High-Speed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... Federal Railroad Administration Notice of Availability of a Final General Conformity Determination for the... advise the public that it issued a Final General Conformity Determination for the Merced to Fresno... General Conformity requirements. The California High Speed Rail Authority (Authority), as the...

  16. The Availability and Utilization of School Library Resources in Some Selected Secondary Schools (High School) in Rivers State

    ERIC Educational Resources Information Center

    Owate, C. N.; Iroha, Okpa

    2013-01-01

    This study investigates the availability and utilization of school library resources by Secondary School (High School) Students. Eight Selected Secondary Schools in Rivers State, Nigeria were chosen based on their performance in external examinations and geographic locations. In carrying out the research, questionnaires were administered to both…

  17. Highly-Parallel, Highly-Compact Computing Structures Implemented in Nanotechnology

    NASA Technical Reports Server (NTRS)

    Crawley, D. G.; Duff, M. J. B.; Fountain, T. J.; Moffat, C. D.; Tomlinson, C. D.

    1995-01-01

    In this paper, we describe work in which we are evaluating how the evolving properties of nano-electronic devices could best be utilized in highly parallel computing structures. Because of their combination of high performance, low power, and extreme compactness, such structures would have obvious applications in spaceborne environments, both for general mission control and for on-board data analysis. However, the anticipated properties of nano-devices mean that the optimum architecture for such systems is by no means certain. Candidates include single instruction multiple datastream (SIMD) arrays, neural networks, and multiple instruction multiple datastream (MIMD) assemblies.

  18. Implementing Scientific Simulation Codes Highly Tailored for Vector Architectures Using Custom Configurable Computing Machines

    NASA Technical Reports Server (NTRS)

    Rutishauser, David

    2006-01-01

    The motivation for this work comes from an observation that amidst the push for Massively Parallel (MP) solutions to high-end computing problems such as numerical physical simulations, large amounts of legacy code exist that are highly optimized for vector supercomputers. Because re-hosting legacy code often requires a complete re-write of the original code, which can be a very long and expensive effort, this work examines the potential to exploit reconfigurable computing machines in place of a vector supercomputer to implement an essentially unmodified legacy source code. Custom and reconfigurable computing resources could be used to emulate an original application's target platform to the extent required to achieve high performance. To arrive at an architecture that delivers the desired performance subject to limited resources involves solving a multi-variable optimization problem with constraints. Prior research in the area of reconfigurable computing has demonstrated that designing an optimum hardware implementation of a given application under hardware resource constraints is an NP-complete problem. The premise of the approach is that the general issue of applying reconfigurable computing resources to the implementation of an application, maximizing the performance of the computation subject to physical resource constraints, can be made a tractable problem by assuming a computational paradigm, such as vector processing. This research contributes a formulation of the problem and a methodology to design a reconfigurable vector processing implementation of a given application that satisfies a performance metric. A generic, parametric, architectural framework for vector processing implemented in reconfigurable logic is developed as a target for a scheduling/mapping algorithm that maps an input computation to a given instance of the architecture. This algorithm is integrated with an optimization framework to arrive at a specification of the architecture parameters

  19. Implementing Self-Managing Work Teams in a High Performance Work Environment

    DTIC Science & Technology

    1990-09-01

    TEAMS IN A HIGH PERFORMANCE WORK ENVIRONMENT THESIS Gerald L. Page, Captain, USAF AFIT/GLM/LSR/90S-42 4~ELECTE SDEC121l990 Approved for public r:elease...studies in this field. vii IMPLEMENTING SELF-MANAGING WORK TEAMS IN A HIGH PERFORMANCE WORK ENVIRONMENT I. Introduction Background Many organizations today...continuous improveimenIt be sustained by a positive work environment " (28:40). General Issue An aspect of TQM that shows great promise in achieving reduced

  20. A high-performance multi-arm environment: Theoretical aspects and practical implementation

    NASA Astrophysics Data System (ADS)

    Zalzala, A. M. S.; Dodds, G. I.; Irwin, G. W.

    1993-05-01

    The development of a multiarm robotic system, where the practical implementation of the system involves motion coordination of two multijoint RTX robots with six degrees of freedom, hosted by a SPARC IPC workstation, is reported. A planning scheme is introduced to provide accurate and coordinated collision free motion. In addition, taking into account the need for high productivity in industrial environments, minimum time movements are imposed by increasing the manipulators' performance to a maximum, thus providing a high performance workcell. A real time case study is included to show the validity and efficiency of the system.

  1. International Conference on Harmonisation; Electronic Transmission of Postmarket Individual Case Safety Reports for Drugs and Biologics, Excluding Vaccines; Availability of Food and Drug Administration Regional Implementation Specifications for ICH E2B(R3) Reporting to the Food and Drug Administration Adverse Event Reporting System. Notice of Availability.

    PubMed

    2016-06-23

    The Food and Drug Administration (FDA) is announcing the availability of its FDA Adverse Event Reporting System (FAERS) Regional Implementation Specifications for the International Conference on Harmonisation (ICH) E2B(R3) Specification. FDA is making this technical specifications document available to assist interested parties in electronically submitting individual case safety reports (ICSRs) (and ICSR attachments) to the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER). This document, entitled "FDA Regional Implementation Specifications for ICH E2B(R3) Implementation: Postmarket Submission of Individual Case Safety Reports (ICSRs) for Drugs and Biologics, Excluding Vaccines" supplements the "E2B(R3) Electronic Transmission of Individual Case Safety Reports (ICSRs) Implementation Guide--Data Elements and Message Specification" final guidance for industry and describes FDA's technical approach for receiving ICSRs, for incorporating regionally controlled terminology, and for adding region-specific data elements when reporting to FAERS.

  2. RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems.

    PubMed

    Repin, Mikhail; Pampou, Sergey; Karan, Charles; Brenner, David J; Garty, Guy

    2017-02-23

    We demonstrate the use of high-throughput biodosimetry platforms based on commercial high-throughput/high-content screening robotic systems. The cytokinesis-block micronucleus (CBMN) assay, using only 20 μl whole blood from a fingerstick, was implemented on a PerkinElmer cell::explorer and General Electric IN Cell Analyzer 2000. On average 500 binucleated cells per sample were detected by our FluorQuantMN software. A calibration curve was generated in the radiation dose range up to 5.0 Gy using the data from 8 donors and 48,083 binucleated cells in total. The study described here demonstrates that high-throughput radiation biodosimetry is practical using current commercial high-throughput/high-content screening robotic systems, which can be readily programmed to perform and analyze robotics-optimized cytogenetic assays. Application to other commercial high-throughput/high-content screening systems beyond the ones used in this study is clearly practical. This approach will allow much wider access to high-throughput biodosimetric screening for large-scale radiological incidents than is currently available.

  3. Implementation of an Efficient High-Accuracy Model for Personal GPS Receivers

    NASA Astrophysics Data System (ADS)

    Yonekawa, Masashi; Tanaka, Toshiyuki

    Positioning systems supported by satellites are increasingly used because of the widespread use of cheap and small personal Global Positioning System (GPS) receivers. Personal GPS receivers are used in cellular phones and car navigation systems. The positioning method used by these personal GPS receivers often produces inaccurate positioning results. Because of the price and size constraints of personal GPS receivers, their accuracy is compromised, and as a result, high-accuracy positioning methods are not widely used. In this paper, we propose a high-accuracy positioning method that can be used with personal GPS receivers. Our proposed method is based on a new approach that takes into account both the systems and solar wind environments. To verify our method, we target the positioning accuracy equivalent to that of the dual-frequency positioning system, which is the highest-accuracy positioning method among all standalone positioning methods. Our approach is implemented in software only, meaning it can be implemented in even the most widely used GPS receivers. Processing speeds associated with the implementation of our proposed method using the CPUs of cellular phones and car navigation systems are well-tolerated.

  4. Effects of light and prey availability on Arctic freshwater protist communities examined by high-throughput DNA and RNA sequencing.

    PubMed

    Charvet, Sophie; Vincent, Warwick F; Lovejoy, Connie

    2014-06-01

    Protists in high-latitude lakes are constrained by cold temperatures, low inorganic nutrient supply and low light availability for much of the year due to ice cover and polar darkness. The lengthening ice-free periods in these freshwater ecosystems due to a warming climate results in increased light availability, but the overall impacts on phytoplankton and other protists are unknown. We experimentally investigated protist community responses to changes in light and prey availability in a dilution series in Ward Hunt Lake (latitude 83°05'N), in the Canadian High Arctic. The communities at the end of the experiment were characterized using high-throughput pyrosequencing of the V4 region of the 18S rRNA gene as a measure of taxonomic presence, and of 18S rRNA (from RNA converted to cDNA) as a taxon-specific indicator of community response. At the end of the experiment under low irradiance, cDNA reads were dominated by photosynthetic dinoflagellate genera, except at the greatest dilution where Cercozoa were most abundant. In contrast, the cDNA reads in the high light treatments were dominated by chrysophytes. Given the known trophic differences among dinoflagellates, cercozoans and chrysophytes, this apparent environmental selection implies that the rise in underwater irradiance associated with increasing ice-free conditions may affect microbial food web structure and function in polar lakes.

  5. Massively parallel implementation of a high order domain decomposition equatorial ocean model

    SciTech Connect

    Ma, H.; McCaffrey, J.W.; Piacsek, S.

    1999-06-01

    The present work is about the algorithms and parallel constructs of a spectral element equatorial ocean model. It shows that high order domain decomposition ocean models can be efficiently implemented on massively parallel architectures, such as the Connection Machine Model CM5. The optimized computational efficiency of the parallel spectral element ocean model comes not only from the exponential convergence of the numerical solution, but also from the work-intensive, medium-grained, geometry-based data parallelism. The data parallelism is created to efficiently implement the spectral element ocean model on the distributed-memory massively parallel computer, which minimizes communication among processing nodes. Computational complexity analysis is given for the parallel algorithm of the spectral element ocean model, and the model's parallel performance on the CM5 is evaluated. Lastly, results from a simulation of wind-driven circulation in low-latitude Atlantic Ocean are described.

  6. MASSIVELY PARALLEL IMPLEMENTATION OF A HIGH ORDER DOMAIN DECOMPOSITION EQUATORIAL OCEAN MODEL

    SciTech Connect

    MA,H.; MCCAFFREY,J.W.; PIACSEK,S.

    1998-07-15

    The present work is about the algorithms and parallel constructs of a spectral element equatorial ocean model. It shows that high order domain decomposition ocean models can be efficiently implemented on massively parallel architectures, such as the Connection Machine Model CM5. The optimized computational efficiency of the parallel spectral element ocean model comes not only from the exponential convergence of the numerical solution, but also from the work-intensive, medium-grained, geometry-based data parallelism. The data parallelism is created to efficiently implement the spectral element ocean model on the distributed-memory massively parallel computer, which minimizes communication among processing nodes. Computational complexity analysis is given for the parallel algorithm of the spectral element ocean model, and the model's parallel performance on the CM5 is evaluated. Lastly, results from a simulation of wind-driven circulation in low-latitude Atlantic ocean are described.

  7. Promoting Professional Socialization Within the Experiential Curriculum: Implementation of a High-stakes Professionalism Rubric

    PubMed Central

    Dintzner, Matthew

    2017-01-01

    Objectives. To describe the implementation of a high-stakes rubric to assess student professionalism in introductory and advanced pharmacy practice experiences (IPPEs and APPEs) to promote the professional socialization of students in the doctor of pharmacy (PharmD) program at Western New England University (WNE). Findings. A professionalism rubric was adapted from the literature to assess the professional behavior of students enrolled in experiential courses based on evaluation of the following criteria: appropriate communication skills with patients and providers, appearance and dress code, timeliness, and initiative. The rubric was implemented in the fall semester of 2013 as a high-stakes component of the assessment within all experiential courses. Students were required to meet expectations for each of the four criteria in order to pass the practice experience, independent of their performance in other course components. Students were assessed by their preceptors at the midpoint and end of each practice experience using the appropriate evaluation tool. Each of the IPPE and APPE evaluation tools included the professionalism rubric as a requirement for assessment. Use of the Professionalism Rubric as a high-stakes assessment tool highlighted professionalism as an important component of the program, making expectations explicit to students and providing leverage to preceptors for holding students accountable. Summary. The Office of Experiential Affairs at WNE has raised awareness of the importance of professionalism and promoted the professional socialization of PharmD students with the use of a high-stakes professionalism rubric. PMID:28289309

  8. Highly proficient bilinguals implement inhibition: Evidence from n-2 language repetition costs.

    PubMed

    Declerck, Mathieu; Thoma, Aniella M; Koch, Iring; Philipp, Andrea M

    2015-11-01

    Several, but not all, models of language control assume that highly proficient bilinguals implement little to no inhibition during bilingual language production. In the current study, we tested this assumption with a less equivocal marker of inhibition (i.e., n-2 language repetition costs) than previous language switching studies have. N-2 language repetition costs denote worse performance when switching back to a recently abandoned language (i.e., worse performance in ABA language sequences than CBA sequences, where A, B, and C refer to different languages). Whereas this marker has solely been used to investigate second-language learners in prior studies, we examined highly proficient bilinguals. The results showed that substantial n-2 language repetition costs can be observed with highly proficient bilinguals. Moreover, this inhibition effect was substantial for all 3 languages, but larger for the 2 dominant languages (Turkish and German) relative to the less proficient language (English). These findings indicate that even highly proficient bilinguals implement inhibition to restrict language production to the target language.

  9. Implementation of a High Throughput Variable Decimation Pane Filter Using the Xilinx System Generator

    SciTech Connect

    RADDER,JERAHMIE WILLIAM

    2003-01-01

    In a Synthetic Aperture Radar (SAR) system, the purpose of the receiver is to process incoming radar signals in order to obtain target information and ultimately construct an image of the target area. Incoming raw signals are usually in the microwave frequency range and are typically processed with analog circuitry, requiring hardware designed specifically for the desired signal processing operations. A more flexible approach is to process the signals in the digital domain. Recent advances in analog-to-digital converter (ADC) and Field Programmable Gate Array (FPGA) technology allow direct digital processing of wideband intermediate frequency (IF) signals. Modern ADCs can achieve sampling rates in excess of 1GS/s, and modern FPGAs can contain millions of logic gates operating at frequencies over 100 MHz. The combination of these technologies is necessary to implement a digital radar receiver capable of performing high speed, sophisticated and scalable DSP designs that are not possible with analog systems. Additionally, FPGA technology allows designs to be modified as the design parameters change without the need for redesigning circuit boards, potentially saving both time and money. For typical radars receivers, there is a need for operation at multiple ranges, which requires filters with multiple decimation rates, i.e., multiple bandwidths. In previous radar receivers, variable decimation was implemented by switching between SAW filters to achieve an acceptable filter configuration. While this method works, it is rather ''brute force'' because it duplicates a large amount of hardware and requires a new filter to be added for each IF bandwidth. By implementing the filter digitally in FPGAs, a larger number of decimation values (and consequently a larger number of bandwidths) can be implemented with no need for extra components. High performance, wide bandwidth radar systems also place high demands on the DSP throughput of a given digital receiver. In such

  10. High School/High Tech Program Guide: An Implementation Guide for High School/High Tech Program Coordinators. Promoting Careers in Science and Technology for High School Students with Disabilities.

    ERIC Educational Resources Information Center

    Office of Disability Employment Policy (DOL), Washington, DC.

    This implementation guide is intended to assist educators in planning, establishing, building, and managing a High School/High Tech project for high school students with disabilities. The program is designed to develop career opportunities, provide activities that will spark an interest in high technology fields, and encourage students to pursue…

  11. Implementation of a school environment intervention to increase physical activity in high school girls.

    PubMed

    Ward, D S; Saunders, R; Felton, G M; Williams, E; Epping, J N; Pate, R R

    2006-12-01

    Physical activity levels begin to decline in childhood and continue falling throughout adolescence, with girls being at greatest risk for inactivity. Schools are ideal settings for helping girls develop and maintain a physically active lifestyle. This paper describes the design and implementation of 'Lifestyle Education for Activity Program', or LEAP. LEAP used a health team approach with participatory strategies to provide training and support, instructional capacity building and opportunities to adapt school instructional program and environmental supports to local needs. The social-ecological model, based on social cognitive theory, served as the organizing framework for the LEAP intervention and elements of the coordinated school health program model as intervention channels. For the 12 intervention schools, LEAP staff documented 191 visits and interactions with 850 individuals over the 2-year period. Teachers reported successful implementation of most components of the intervention and demonstrated optimism for sustainability. These results indicate that a facilitative approach to intervention implementation can be used successfully to engage school personnel, and to change instructional programs and school environments to increase the physical activity level of high school girls.

  12. Numerical implementation of a crystal plasticity model with dislocation transport for high strain rate applications

    NASA Astrophysics Data System (ADS)

    Mayeur, Jason R.; Mourad, Hashem M.; Luscher, Darby J.; Hunter, Abigail; Kenamond, Mark A.

    2016-05-01

    This paper details a numerical implementation of a single crystal plasticity model with dislocation transport for high strain rate applications. Our primary motivation for developing the model is to study the influence of dislocation transport and conservation on the mesoscale response of metallic crystals under extreme thermo-mechanical loading conditions (e.g. shocks). To this end we have developed a single crystal plasticity theory (Luscher et al (2015)) that incorporates finite deformation kinematics, internal stress fields caused by the presence of geometrically necessary dislocation gradients, advection equations to model dislocation density transport and conservation, and constitutive equations appropriate for shock loading (equation of state, drag-limited dislocation velocity, etc). In the following, we outline a coupled finite element-finite volume framework for implementing the model physics, and demonstrate its capabilities in simulating the response of a [1 0 0] copper single crystal during a plate impact test. Additionally, we explore the effect of varying certain model parameters (e.g. mesh density, finite volume update scheme) on the simulation results. Our results demonstrate that the model performs as intended and establishes a baseline of understanding that can be leveraged as we extend the model to incorporate additional and/or refined physics and move toward a multi-dimensional implementation.

  13. Variables that impact the implementation of project-based learning in high school science

    NASA Astrophysics Data System (ADS)

    Cunningham, Kellie

    Wagner and colleagues (2006) state the mediocrity of teaching and instructional leadership is the central problem that must be addressed if we are to improve student achievement. Educational reform efforts have been initiated to improve student performance and to hold teachers and school leaders accountable for student achievement (Wagner et al., 2006). Specifically, in the area of science, goals for improving student learning have led reformers to establish standards for what students should know and be able to do, as well as what instructional methods should be used. Key concepts and principles have been identified for student learning. Additionally, reformers recommend student-centered, inquiry-based practices that promote a deep understanding of how science is embedded in the everyday world. These new approaches to science education emphasize inquiry as an essential element for student learning (Schneider, Krajcik, Marx, & Soloway, 2002). Project-based learning (PBL) is an inquiry-based instructional approach that addresses these recommendations for science education reform. The objective of this research was to study the implementation of project-based learning (PBL) in an urban school undergoing reform efforts and identify the variables that positively or negatively impacted the PBL implementation process and its outcomes. This study responded to the need to change how science is taught by focusing on the implementation of project-based learning as an instructional approach to improve student achievement in science and identify the role of both school leaders and teachers in the creation of a school environment that supports project-based learning. A case study design using a mixed-method approach was used in this study. Data were collected through individual interviews with the school principal, science instructional coach, and PBL facilitator. A survey, classroom observations and interviews involving three high school science teachers teaching grades 9

  14. High Performance Data Clustering: A Comparative Analysis of Performance for GPU, RASC, MPI, and OpenMP Implementations*

    PubMed Central

    Yang, Luobin; Chiu, Steve C.; Liao, Wei-Keng; Thomas, Michael A.

    2013-01-01

    Compared to Beowulf clusters and shared-memory machines, GPU and FPGA are emerging alternative architectures that provide massive parallelism and great computational capabilities. These architectures can be utilized to run compute-intensive algorithms to analyze ever-enlarging datasets and provide scalability. In this paper, we present four implementations of K-means data clustering algorithm for different high performance computing platforms. These four implementations include a CUDA implementation for GPUs, a Mitrion C implementation for FPGAs, an MPI implementation for Beowulf compute clusters, and an OpenMP implementation for shared-memory machines. The comparative analyses of the cost of each platform, difficulty level of programming for each platform, and the performance of each implementation are presented. PMID:25309040

  15. High Performance Data Clustering: A Comparative Analysis of Performance for GPU, RASC, MPI, and OpenMP Implementations.

    PubMed

    Yang, Luobin; Chiu, Steve C; Liao, Wei-Keng; Thomas, Michael A

    2014-10-01

    Compared to Beowulf clusters and shared-memory machines, GPU and FPGA are emerging alternative architectures that provide massive parallelism and great computational capabilities. These architectures can be utilized to run compute-intensive algorithms to analyze ever-enlarging datasets and provide scalability. In this paper, we present four implementations of K-means data clustering algorithm for different high performance computing platforms. These four implementations include a CUDA implementation for GPUs, a Mitrion C implementation for FPGAs, an MPI implementation for Beowulf compute clusters, and an OpenMP implementation for shared-memory machines. The comparative analyses of the cost of each platform, difficulty level of programming for each platform, and the performance of each implementation are presented.

  16. [Not Available].

    PubMed

    Jelassi, Mohamed Larbi; Benlmouden, Amine; Lefeuvre, Sandrine; Mainardi, Jean-Luc; Billaud, Eliane M

    2011-01-01

    Level of Evidence for Therapeutic Drug Monitoring of Vancomycin. Vancomycin is an antibiotic for exclusive hospital use administrated in intravenous infusion to treat systemic infections. It is mainly eliminated by kidneys and potentially nephrotoxic. Data available show that Therapeutic Drug Monitoring (TDM) of vancomycin is highly recommended. It aims to ensure efficacy and avoid resistance by maintaining trough plasma concentrations above the MIC. Secondary, vancomycine TDM may be indicated to prevent nephrotoxicity in high risk patients. TDM is often underwent at steady state (48 to 72 h after the treatment initiation) unless in case of renal impairment (24 h). While compared with intermittent administration, continuous infusion did not result in prognosis improvement; however it resulted in lower pharmacokinetic variability and better cost-efficiency. Targeted trough concentrations for intermittent infusion are between 15 and 20 mg/L (up to 25-30 mg/L for GISA). In case of continuous infusion, targets are higher (25 to 40 mg/L).

  17. High altitude mine waste remediation -- Implementation of the Idarado remedial action plan

    SciTech Connect

    Hardy, A.J.; Redmond, J.V.; River, R.A.; Davis, C.S.

    1999-07-01

    The Idarado Mine in Colorado's San Juan Mountains includes 11 tailing areas, numerous waste rock dumps, and a large number of underground openings connected by over 100 miles of raises and drifts. The tailings and mine wastes were generated from different mining and milling operations between 1975 and 1978. the Idarado Remedial Action Plan (RAP) was an innovative 5-year program developed for remediating the impacts of historic mining activities in the San Miguel River and Red Mountain Creek drainages. The challenges during implementation included seasonal access limitations due to the high altitude construction areas, high volumes of runoff during snow melt, numerous abandoned underground openings and stopped-out veins, and high profile sites adjacent to busy jeep trails and a major ski resort town. Implementation of the RAP has included pioneering efforts in engineering design and construction of remedial measures. Innovative engineering designs included direct revegetation techniques for the stabilization of tailings piles, concrete cutoff walls and French drains to control subsurface flows, underground water controls that included pipelines, weeplines, and portal collection systems, and various underground structures to collect and divert subsurface flows often exceeding 2,000 gpm. Remote work locations have also required the use of innovative construction techniques such as heavy lift helicopters to move construction materials to mines above 10,000 feet. This paper describes the 5-year implementation program which has included over 1,000,000 cubic yards of tailing regrading, application of 5,000 tons of manure and 26,000 tons of limestone, and construction of over 10,000 feet of pipeline and approximately 45,000 feet of diversion channel.

  18. Principles and practical implementation for high resolution multi-sensor QPE

    NASA Astrophysics Data System (ADS)

    Chandra, C. V.; Lim, S.; Cifelli, R.

    2011-12-01

    The multi-sensor Quantitative Precipitation Estimation (MPE) is a principle and a practical concept and is becoming a well-known term in the scientific circles of hydrology and atmospheric science. The main challenge in QPE is that precipitation is a highly variable quantity with extensive spatial and temporal variability at multiple scales. There are MPE products produced from satellites, radars, models and ground sensors. There are MPE products at global scale (Heinemann et al. 2002), continental scale (Seo et al. 2010; Zhang et al. 2011) and regional scale (Kitzmiller et al. 2011). Lots of the MPE products are used to alleviate the problems of one type of sensor by another. Some multi-sensor products are used to move across scales. This paper looks at a comprehensive view of the "concept of multi sensor precipitation estimate", from different perspectives. This paper delineates the MPE problem into three categories namely, a) Scale based MPE, b) MPE for accuracy enhancement and coverage and c) Integrative across scales. For example, by introducing dual polarization radar data to the MPE system, QPE can be improved significantly. In last decade, dual polarization radars are becoming an important tool for QPE in operational networks. Dual polarization radars offer an advantage to interpret more accurate physical models by providing information of the size, shape, phase and orientation of hydrometers (Bringi and Chandrasekar 2001). In addition, these systems have the ability to provide measurements that are immune to absolute radar calibration and partial beam blockage as well as help in data quality enhancement. By integrating these characteristics of dual polarization radar, QPE performance can be improved in comparison of single polarization radar based QPE (Cifelli and Chandrasekar 2010). Dual-polarization techniques have been applied to S and C band radar systems for several decades and higher frequency system such as X band are now widely available to the

  19. Implementation of the United States-Russian Highly Enriched Uranium Agreement: Current Status & Prospects

    SciTech Connect

    Rutkowski, E; Armantrout, G; Mastal, E; Glaser, J; Benton, J

    2004-07-27

    The National Nuclear Security Administration's (NNSA) Highly Enriched Uranium (HEU) Transparency Implementation Program (TIP) monitors and provides assurance that Russian weapons-grade HEU is processed into low enriched uranium (LEU) under the transparency provisions of the 1993 United States (U.S.)-Russian HEU Purchase Agreement. Meeting the Agreement's transparency provisions is not just a program requirement; it is a legal requirement. The HEU Purchase Agreement requires transparency measures to be established to provide assurance that the nonproliferation objectives of the Agreement are met. The Transparency concept has evolved into a viable program that consists of complimentary elements that provide necessary assurances. The key elements include: (1) monitoring by technical experts; (2) independent measurements of enrichment and flow; (3) nuclear material accountability documents from Russian plants; and (4) comparison of transparency data with declared processing data. In the interest of protecting sensitive information, the monitoring is neither full time nor invasive. Thus, an element of trust is required regarding declared operations that are not observed. U.S. transparency monitoring data and independent instrument measurements are compared with plant accountability records and other declared processing data to provide assurance that the nonproliferation objectives of the 1993 Agreement are being met. Similarly, Russian monitoring of U. S. storage and fuel fabrication operations provides assurance to the Russians that the derived LEU is being used in accordance with the Agreement. The successful implementation of the Transparency program enables the receipt of Russian origin LEU into the United States. Implementation of the 1993 Agreement is proceeding on schedule, with the permanent elimination of over 8,700 warhead equivalents of HEU. The successful implementation of the Transparency program has taken place over the last 10 years and has provided the

  20. Performance Sensitivity Studies on the PIAA Implementation of the High-Contrast Imaging Testbed

    NASA Technical Reports Server (NTRS)

    Sidick, Erkin; Lou, John Z.; Shaklan, Stuart; Levine, Marie

    2009-01-01

    We have investigated the dependence of the High Contrast Imaging Testbed (HCIT) Phase Induced Amplitude Apodization (PIAA) coronagraph system performance on the rigid-body perturbations of various optics. The structural design of the optical system as well as the parameters of various optical elements used in the analysis are drawn from those of the PIAA/HCIT system that have been and will be implemented, and the simulation takes into account the surface errors of various optics. In this paper, we report our findings when the input light is a narrowband beam.

  1. Formulation and implementation of a high-order 3-D domain integral method for the extraction of energy release rates

    NASA Astrophysics Data System (ADS)

    Ozer, H.; Duarte, C. A.; Al-Qadi, I. L.

    2012-04-01

    This article presents a three dimensional (3-D) formulation and implementation of a high-order domain integral method for the computation of energy release rate. The method is derived using surface and domain formulations of the J-integral and the weighted residual method. The J-integral along 3-D crack fronts is approximated by high-order Legendre polynomials. The proposed implementation is tailored for the Generalized/eXtended Finite Element Method and can handle discontinuities arbitrarily located within a finite element mesh. The domain integral calculations are based on the same integration elements used for the computation of the stiffness matrix. Discontinuities of the integrands across crack surfaces and across computational element boundaries are fully accounted for. The proposed method is able to deliver smooth approximations and to capture the boundary layer behavior of the J-integral using tetrahedral meshes. Numerical simulations of mode-I and mixed mode benchmark fracture mechanics examples verify expected convergence rates for the computed energy release rates. The results are also in good agreement with other numerical solutions available in the literature.

  2. Psychological first aid following trauma: implementation and evaluation framework for high-risk organizations.

    PubMed

    Forbes, David; Lewis, Virginia; Varker, Tracey; Phelps, Andrea; O'Donnell, Meaghan; Wade, Darryl J; Ruzek, Josef I; Watson, Patricia; Bryant, Richard A; Creamer, Mark

    2011-01-01

    International clinical practice guidelines for the management of psychological trauma recommend Psychological First Aid (PFA) as an early intervention for survivors of potentially traumatic events. These recommendations are consensus-based, and there is little published evidence assessing the effectiveness of PFA. This is not surprising given the nature of the intervention and the complicating factors involved in any evaluation of PFA. There is, nevertheless, an urgent need for stronger evidence evaluating its effectiveness. The current paper posits that the implementation and evaluation of PFA within high risk organizational settings is an ideal place to start. The paper provides a framework for a phasic approach to implementing PFA within such settings and presents a model for evaluating its effectiveness using a logic- or theory-based approach which considers both pre-event and post-event factors. Phases 1 and 2 of the PFA model are pre-event actions, and phases 3 and 4 are post-event actions. It is hoped that by using the Phased PFA model and evaluation method proposed in this paper, future researchers will begin to undertake the important task of building the evidence about the most effective approach to providing PFA in high risk organizational and community disaster settings.

  3. Centrality dependence of high energy jets in p+Pb collisions at energies available at the CERN Large Hadron Collider

    DOE PAGES

    Bzdak, Adam; Skokov, Vladimir; Bathe, Stefan

    2016-04-08

    We investigate the recently measured centrality dependence of high energy jets in proton-lead collisions at the LHC. Here, we hypothesize that events with jets of very high energy (a few hundred GeV) are characterized by a suppressed number of soft particles, thus shifting these events into more peripheral bins. This naturally results in the suppression (enhancement) of the nuclear modification factor, RpA, in central (peripheral) collisions. Our calculations suggest that a moderate suppression of the order of 20%, for 103 GeV jets, can quantitatively reproduce the experimental data. Finally, we further extract the suppression factor as a function of jetmore » energy and test our conjecture using available RpA data for various centralities.« less

  4. Next Generation Fast RF Interlock Module and ATCA Adapter for ILC High Availability RF Test Station Demonstration

    SciTech Connect

    Larsen, R

    2009-10-17

    High availability interlocks and controls are required for the ILC (International Linear Collider) L-Band high power RF stations. A new F3 (Fast Fault Finder) VME module has been developed to process both fast and slow interlocks using FPGA logic to detect the interlock trip excursions. This combination eliminates the need for separate PLC (Programmable Logic Controller) control of slow interlocks. Modules are chained together to accommodate as many inputs as needed. In the next phase of development the F3's will be ported to the new industry standard ATCA (Advanced Telecom Computing Architecture) crate (shelf) via a specially designed VME adapter module with IPMI (Intelligent Platform Management Interface). The goal is to demonstrate auto-failover and hot-swap for future partially redundant systems.

  5. Neural network Z-plane implementation with very high interconnection rates

    NASA Astrophysics Data System (ADS)

    Carson, John C.

    1990-11-01

    Neural networks offer the potential for a quantum leap in the capabilities of imaging sensor systems. The critical neural network implementation factors are: weighted interconnect between all detector outputs; parallel, linear processing of each detector output; fan-out to multiple (thousands) processing nodes per detector output and the ability to independently change interconnect weights and processor node connections within the detector integration times. For a 128 x 128 pixel detector array, the number of desirable interconnects could be as high as iO per second, compared to the approximately iO rates achieved presently with off-focal plane digital processors. Irvine Sensors Corporation (ISC) has conceived a new way of interconnecting 3-D focal plane readout modules and of laying out their component integrated circuits that appears to fulfill the very high interconnect rate requirements. This concept is described and mterconnectivity and other performance attributes are discussed.

  6. Vocational High School Teachers' Difficulties in Implementing the Assessment in Curriculum 2013 in Yogyakarta Province of Indonesia

    ERIC Educational Resources Information Center

    Retnawati, Heri; Hadi, Samsul; Nugraha, Ariadie Chandra

    2016-01-01

    The study aims to describe vocational high school teachers' difficulties in implementing the assessment within Curriculum 2013, which has been implemented since July 2013 in several Indonesian schools and which might have been in effect in all schools around 2014. The study was descriptive explorative research by means of qualitative data…

  7. The Relationship between Professional Learning Community Implementation and Academic Achievement and Graduation Rates in Georgia High Schools

    ERIC Educational Resources Information Center

    Hardinger, Regina Gail

    2013-01-01

    Many educational administrators in Georgia continue to struggle with low student academic achievement and low high school graduation rates. DuFour's professional learning community (PLC) theory suggests a positive relationship between levels of PLC implementation and academic achievement and between levels of PLC implementation and graduation…

  8. Case Studies of Teachers' Perceptions and Their Enactment Processes When Implementing Multiple Reforms in Urban High School Mathematics

    ERIC Educational Resources Information Center

    Samaniego, Kimberly Anne OBrien

    2013-01-01

    Efforts to improve student performance on high-stakes assessments in mathematics place teachers in the epicenter of multiple reform expectations. While studies have documented how teachers implement single reforms, very little is known about teachers' implementation processes when multiple expectations are imposed. With a focus on how…

  9. High level implementation of geometric multigrid solvers for finite element problems: Applications in atmospheric modelling

    NASA Astrophysics Data System (ADS)

    Mitchell, Lawrence; Müller, Eike Hermann

    2016-12-01

    The implementation of efficient multigrid preconditioners for elliptic partial differential equations (PDEs) is a challenge due to the complexity of the resulting algorithms and corresponding computer code. For sophisticated (mixed) finite element discretisations on unstructured grids an efficient implementation can be very time consuming and requires the programmer to have in-depth knowledge of the mathematical theory, parallel computing and optimisation techniques on manycore CPUs. In this paper we show how the development of bespoke multigrid preconditioners can be simplified significantly by using a framework which allows the expression of the each component of the algorithm at the correct abstraction level. Our approach (1) allows the expression of the finite element problem in a language which is close to the mathematical formulation of the problem, (2) guarantees the automatic generation and efficient execution of parallel optimised low-level computer code and (3) is flexible enough to support different abstraction levels and give the programmer control over details of the preconditioner. We use the composable abstractions of the Firedrake/PyOP2 package to demonstrate the efficiency of this approach for the solution of strongly anisotropic PDEs in atmospheric modelling. The weak formulation of the PDE is expressed in Unified Form Language (UFL) and the lower PyOP2 abstraction layer allows the manual design of computational kernels for a bespoke geometric multigrid preconditioner. We compare the performance of this preconditioner to a single-level method and hypre's BoomerAMG algorithm. The Firedrake/PyOP2 code is inherently parallel and we present a detailed performance analysis for a single node (24 cores) on the ARCHER supercomputer. Our implementation utilises a significant fraction of the available memory bandwidth and shows very good weak scaling on up to 6,144 compute cores.

  10. A C++11 implementation of arbitrary-rank tensors for high-performance computing

    NASA Astrophysics Data System (ADS)

    Aragón, Alejandro M.

    2014-11-01

    This article discusses an efficient implementation of tensors of arbitrary rank by using some of the idioms introduced by the recently published C++ ISO Standard (C++11). With the aims at providing a basic building block for high-performance computing, a single Array class template is carefully crafted, from which vectors, matrices, and even higher-order tensors can be created. An expression template facility is also built around the array class template to provide convenient mathematical syntax. As a result, by using templates, an extra high-level layer is added to the C++ language when dealing with algebraic objects and their operations, without compromising performance. The implementation is tested running on both CPU and GPU. Catalogue identifier: AESA_v1_1 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AESA_v1_1.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: GNU Lesser General Public License, version 3 No. of lines in distributed program, including test data, etc.: 12 376 No. of bytes in distributed program, including test data, etc.: 81 669 Distribution format: tar.gz Programming language: C++. Computer: All modern architectures. Operating system: Linux/Unix/Mac OS. RAM: Problem dependent Classification: 5. External routines: GNU CMake build system and BLAS implementation. NVIDIA CUBLAS for GPU computing. Does the new version supersede the previous version?: Yes Catalogue identifier of previous version: AESA_v1_0 Journal reference of previous version: Comput. Phys. Comm. 185 (2014) 1681 Nature of problem: Tensors are a basic building block for any program in scientific computing. Yet, tensors are not a built-in component of the C++ programming language. Solution method: An arbitrary-rank tensor class template is crafted by using the new features introduced by the C++11 set of requirements. In addition, an entire expression template facility is built on top, to provide mathematical

  11. Interactions Between Temperature and Nutrient Availability in Mediating Microbial Respiration in High Arctic Polar Semi-desert Soils

    NASA Astrophysics Data System (ADS)

    Holland, K. J.; Sullivan, P.; Wallenstein, M.; Arens, S.; Schimel, J. P.; Welker, J. M.

    2005-12-01

    Field respiration measurements in high arctic polar semi-desert in northern Greenland suggest a divergence in respiration rates of microbial communities in fertilization treatments at temperatures above 4°C. We hypothesized that this divergence could be attributed to either greater temperature responsiveness of microbial communities in nitrogen fertilized treatments, or to increased substrate availability in nitrogen fertilization treatments at higher temperatures. Microbial respiration responses to labile substrate addition were equal across fertilization treatments, suggesting that microbial communities had similar temperature sensitivities. To determine whether substrate availability differed between fertilization treatments, we measured 13CO2 of respiration at four temperatures. With increased temperature, rates of CO2 efflux increased and isotopic signatures of respired carbon became lighter, suggesting increasing turnover of more recalcitrant C at higher temperatures. Respiration of nitrogen fertilized soils had lighter 13CO2 signatures than ambient soils, suggesting that nitrogen might increase turnover of more recalcitrant soil carbon. These data suggest the divergence in CO2 efflux in the nitrogen fertilization treatments could be mediated by increasing availability of recalcitrant carbon.

  12. Improved virus removal by high-basicity polyaluminum coagulants compared to commercially available aluminum-based coagulants.

    PubMed

    Shirasaki, N; Matsushita, T; Matsui, Y; Oshiba, A; Marubayashi, T; Sato, S

    2014-01-01

    We investigated the effects of basicity, sulfate content, and aluminum hydrolyte species on the ability of polyaluminum chloride (PACl) coagulants to remove F-specific RNA bacteriophages from river water at a pH range of 6-8. An increase in PACl basicity from 1.5 to 2.1 and the absence of sulfate led to a reduction of the amount of monomeric aluminum species (i.e., an increase of the total amount of polymeric aluminum and colloidal aluminum species) in the PACl, to an increase in the colloid charge density of the PACl, or to both and, as a result, to high virus removal efficiency. The efficiency of virus removal at around pH 8 observed with PACl-2.1c, a nonsulfated high-basicity PACl (basicity 2.1-2.2) with a high colloidal aluminum content, was larger than that observed with PACl-2.1b, a nonsulfated high-basicity PACl (basicity 2.1-2.2) with a high polymeric aluminum content. In contrast, although extremely high basicity PACls (e.g., PACl-2.7ns, basicity 2.7) effectively removed turbidity and UV260-absorbing natural organic matter and resulted in a very low residual aluminum concentration, the virus removal ratio with PACl-2.7ns was smaller than the ratio with PACl-2.1c at around pH 8, possibly as a result of a reduction of the colloid charge density of the PACl as the basicity was increased from 2.1 to 2.7. Liquid (27)Al NMR analysis revealed that PACl-2.1c contained Al30 species, which was not the case for PACl-2.1b or PACl-2.7ns. This result suggests that Al30 species probably played a major role in virus removal during the coagulation process. In summary, PACl-2.1c, which has high colloidal aluminum content, contains Al30 species, and has a high colloid charge density, removed viruses more efficiently (>4 log10 for infectious viruses) than the other aluminum-based coagulants-including commercially available PACls (basicity 1.5-1.8), alum, and PACl-2.7ns-over the entire tested pH (6-8) and coagulant dosage (0.54-5.4 mg-Al/L) ranges.

  13. Development, Implementation and Application of Micromechanical Analysis Tools for Advanced High Temperature Composites

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This document contains the final report to the NASA Glenn Research Center (GRC) for the research project entitled Development, Implementation, and Application of Micromechanical Analysis Tools for Advanced High-Temperature Composites. The research supporting this initiative has been conducted by Dr. Brett A. Bednarcyk, a Senior Scientist at OM in Brookpark, Ohio from the period of August 1998 to March 2005. Most of the work summarized herein involved development, implementation, and application of enhancements and new capabilities for NASA GRC's Micromechanics Analysis Code with Generalized Method of Cells (MAC/GMC) software package. When the project began, this software was at a low TRL (3-4) and at release version 2.0. Due to this project, the TRL of MAC/GMC has been raised to 7 and two new versions (3.0 and 4.0) have been released. The most important accomplishments with respect to MAC/GMC are: (1) A multi-scale framework has been built around the software, enabling coupled design and analysis from the global structure scale down to the micro fiber-matrix scale; (2) The software has been expanded to analyze smart materials; (3) State-of-the-art micromechanics theories have been implemented and validated within the code; (4) The damage, failure, and lifing capabilities of the code have been expanded from a very limited state to a vast degree of functionality and utility; and (5) The user flexibility of the code has been significantly enhanced. MAC/GMC is now the premier code for design and analysis of advanced composite and smart materials. It is a candidate for the 2005 NASA Software of the Year Award. The work completed over the course of the project is summarized below on a year by year basis. All publications resulting from the project are listed at the end of this report.

  14. Implementation of a Novel Flight Tracking and Recovery Package for High Altitude Ballooning Missions

    NASA Astrophysics Data System (ADS)

    Fatima, Aqsa; Nekkanti, Sanjay; Mohan Suri, Ram; Shankar, Divya; Prasad Nagendra, Narayan

    High altitude ballooning is typically used for scientific missions including stratospheric observations, aerological observations, and near space environment technology demonstration. The usage of stratospheric balloons is a cost effective method to pursue several scientific and technological avenues against using satellites in the void of space. Based on the Indian Institute of Astrophysics (IIA) ballooning program for studying Comet ISON using high altitude ballooning, a cost effective flight tracking and recovery package for ballooning missions has been developed using open source hardware. The flight tracking and recovery package is based on using Automatic Packet Reporting System (APRS) and has a redundant Global System for Mobile Communications (GSM) based Global Positioning System (GPS) tracker. The APRS based tracker uses AX.25 protocol for transmission of the GPS coordinates (latitude, longitude, altitude, time) alongside the heading and health parameters of the board (voltage, temperature). APRS uses amateur radio frequencies where data is transmitted in packet messaging format, modulated by radio signals. The receiver uses Very High Frequency (VHF) transceiver to demodulate the APRS signals. The data received will be decoded using MixW (open source software). A bridge will be established between the decoding software and the APRS software. The flight path will be predicted before the launch and the real time position co-ordinates will be used to obtain the real time flight path that will be uploaded online using the bridge connection. We also use open source APRS software to decode and Google Earth to display the real time flight path. Several ballooning campaigns do not employ payload data transmission in real time, which makes the flight tracking and package recovery vital for data collection and recovery of flight instruments. The flight tracking and recovery package implemented in our missions allow independent development of the payload package

  15. High-power ultrafast Yb:fiber laser frequency combs using commercially available components and basic fiber tools

    NASA Astrophysics Data System (ADS)

    Li, Xinlong; Reber, Melanie A. R.; Corder, Christopher; Chen, Yuning; Zhao, Peng; Allison, Thomas K.

    2016-09-01

    We present a detailed description of the design, construction, and performance of high-power ultrafast Yb:fiber laser frequency combs in operation in our laboratory. We discuss two such laser systems: an 87 MHz, 9 W, 85 fs laser operating at 1060 nm and an 87 MHz, 80 W, 155 fs laser operating at 1035 nm. Both are constructed using low-cost, commercially available components, and can be assembled using only basic tools for cleaving and splicing single-mode fibers. We describe practical methods for achieving and characterizing low-noise single-pulse operation and long-term stability from Yb:fiber oscillators based on nonlinear polarization evolution. Stabilization of the combs using a variety of transducers, including a new method for tuning the carrier-envelope offset frequency, is discussed. High average power is achieved through chirped-pulse amplification in simple fiber amplifiers based on double-clad photonic crystal fibers. We describe the use of these combs in several applications, including ultrasensitive femtosecond time-resolved spectroscopy and cavity-enhanced high-order harmonic generation.

  16. Workplace characterisation in mixed neutron-gamma fields, specific requirements and available methods at high-energy accelerators.

    PubMed

    Silari, Marco

    2007-01-01

    A good knowledge of the radiation field present outside the shielding of high-energy particle accelerators is very important to be able to select the type of detectors (active and/or passive) to be employed for area monitoring and the type of personal dosemeter required for estimating the doses received by individuals. Around high-energy electron and proton accelerators the radiation field is usually dominated by neutrons and photons, with minor contributions from other charged particles. Under certain circumstances, muon radiation in the forward beam direction may also be present. Neutron dosimetry and spectrometry are of primary importance to characterise the radiation field and thus to correctly evaluate personnel exposure. Starting from the beam parameters important for radiation monitoring, the paper first briefly reviews the stray radiation fields encountered around high-energy accelerators and then addresses the relevant techniques employed for their monitoring. Recent developments to increase the response of neutron measuring devices beyond 10-20 MeV are illustrated. Instruments should be correctly calibrated either in reference monoenergetic radiation fields or in a field similar to the field in which they are used (workplace calibration). The importance of the instrument calibration is discussed and available neutron calibration facilities are briefly reviewed.

  17. High-power ultrafast Yb:fiber laser frequency combs using commercially available components and basic fiber tools.

    PubMed

    Li, Xinlong; Reber, Melanie A R; Corder, Christopher; Chen, Yuning; Zhao, Peng; Allison, Thomas K

    2016-09-01

    We present a detailed description of the design, construction, and performance of high-power ultrafast Yb:fiber laser frequency combs in operation in our laboratory. We discuss two such laser systems: an 87 MHz, 9 W, 85 fs laser operating at 1060 nm and an 87 MHz, 80 W, 155 fs laser operating at 1035 nm. Both are constructed using low-cost, commercially available components, and can be assembled using only basic tools for cleaving and splicing single-mode fibers. We describe practical methods for achieving and characterizing low-noise single-pulse operation and long-term stability from Yb:fiber oscillators based on nonlinear polarization evolution. Stabilization of the combs using a variety of transducers, including a new method for tuning the carrier-envelope offset frequency, is discussed. High average power is achieved through chirped-pulse amplification in simple fiber amplifiers based on double-clad photonic crystal fibers. We describe the use of these combs in several applications, including ultrasensitive femtosecond time-resolved spectroscopy and cavity-enhanced high-order harmonic generation.

  18. FPGA Implementation of Stereo Disparity with High Throughput for Mobility Applications

    NASA Technical Reports Server (NTRS)

    Villalpando, Carlos Y.; Morfopolous, Arin; Matthies, Larry; Goldberg, Steven

    2011-01-01

    High speed stereo vision can allow unmanned robotic systems to navigate safely in unstructured terrain, but the computational cost can exceed the capacity of typical embedded CPUs. In this paper, we describe an end-to-end stereo computation co-processing system optimized for fast throughput that has been implemented on a single Virtex 4 LX160 FPGA. This system is capable of operating on images from a 1024 x 768 3CCD (true RGB) camera pair at 15 Hz. Data enters the FPGA directly from the cameras via Camera Link and is rectified, pre-filtered and converted into a disparity image all within the FPGA, incurring no CPU load. Once complete, a rectified image and the final disparity image are read out over the PCI bus, for a bandwidth cost of 68 MB/sec. Within the FPGA there are 4 distinct algorithms: Camera Link capture, Bilinear rectification, Bilateral subtraction pre-filtering and the Sum of Absolute Difference (SAD) disparity. Each module will be described in brief along with the data flow and control logic for the system. The system has been successfully fielded upon the Carnegie Mellon University's National Robotics Engineering Center (NREC) Crusher system during extensive field trials in 2007 and 2008 and is being implemented for other surface mobility systems at JPL.

  19. Issues with implementing a high-quality lung cancer screening program.

    PubMed

    Mulshine, James L; D'Amico, Thomas A

    2014-01-01

    After a comprehensive review of the evidence, the United States Preventive Services Task Force recently endorsed screening with low-dose computed tomography as an early detection approach that has the potential to significantly reduce deaths due to lung cancer. Prudent implementation of lung cancer screening as a high-quality preventive health service is a complex challenge. The clinical evaluation and management of high-risk cohorts in the absence of symptoms mandates an approach that differs significantly from that of symptom-detected lung cancer. As with other cancer screenings, it is essential to provide to informed at-risk individuals a safe, high-quality, cost-effective, and accessible service. In this review, the components of a successful screening program are discussed as we begin to disseminate lung cancer screening as a national resource to improve outcomes with this lethal cancer. This information about lung cancer screening will assist clinicians with communications about the potential benefits and harms of this service for high-risk individuals considering participation in the screening process.

  20. High phosphate availability as a possible cause for massive cyanobacterial production of oxygen in the Paleoproterozoic atmosphere

    NASA Astrophysics Data System (ADS)

    Papineau, Dominic; Purohit, Ritesh; Fogel, Marilyn L.; Shields-Zhou, Graham A.

    2013-01-01

    have arisen from the biological response to high phosphate availability. We conclude that increased phosphate availability during and after the Paleoproterozoic Lomagundi-Jatuli event likely caused cyanobacterial blooms and was a key factor in the oxygenation of Earth's atmosphere. Increasing oxygenation of the shallow ocean seafloor favored the removal of excess phosphate as authigenic apatite, thus dampening effects of weathering increases on organic burial and marine δ13Ccarb after about 2.0 Ga.

  1. Identification of Microorganisms in Duck Meat Products Available in Korea and the Effect of High Hydrostatic Pressure.

    PubMed

    Kim, Hyun-Joo; Yong, Hae In; Lee, Hyun Jung; Jung, Samooel; Kwon, Joong-Ho; Heo, Kang Nyung; Jo, Cheorun

    2016-01-01

    The objective of this study was to investigate the microbial count of duck meat and duck meat products commercially available in Korea. High hydrostatic pressure (HHP) treatment was applied at 0.1, 300, 400, and 500 MPa for 5 min to enhance the microbiological safety of duck meats. The levels of total aerobic bacteria were in the ranges of 3.53-6.19 and 3.62-6.85 Log CFU/g in raw and smoked duck products, respectively. By DNA sequence analysis, we identified microorganisms responsible for spoilage, with the most common species in the raw and smoked duck products being Aeromonas spp. or Pseudomonas spp. and Leuconostoc mesenteroides, respectively. HHP treatment significantly reduced the levels of total aerobic bacteria in raw and smoked duck products. This study demonstrates that HHP treatment may be used to effectively improve the safety of raw and smoked duck meat products.

  2. Identification of Microorganisms in Duck Meat Products Available in Korea and the Effect of High Hydrostatic Pressure

    PubMed Central

    Kim, Hyun-Joo; Jung, Samooel; Kwon, Joong-Ho; Heo, Kang Nyung

    2016-01-01

    The objective of this study was to investigate the microbial count of duck meat and duck meat products commercially available in Korea. High hydrostatic pressure (HHP) treatment was applied at 0.1, 300, 400, and 500 MPa for 5 min to enhance the microbiological safety of duck meats. The levels of total aerobic bacteria were in the ranges of 3.53-6.19 and 3.62-6.85 Log CFU/g in raw and smoked duck products, respectively. By DNA sequence analysis, we identified microorganisms responsible for spoilage, with the most common species in the raw and smoked duck products being Aeromonas spp. or Pseudomonas spp. and Leuconostoc mesenteroides, respectively. HHP treatment significantly reduced the levels of total aerobic bacteria in raw and smoked duck products. This study demonstrates that HHP treatment may be used to effectively improve the safety of raw and smoked duck meat products. PMID:27194939

  3. Statistical analysis of the limitation of half integer resonances on the available momentum acceptance of the High Energy Photon Source

    NASA Astrophysics Data System (ADS)

    Jiao, Yi; Duan, Zhe

    2017-01-01

    In a diffraction-limited storage ring, half integer resonances can have strong effects on the beam dynamics, associated with the large detuning terms from the strong focusing and strong sextupoles as required for an ultralow emittance. In this study, the limitation of half integer resonances on the available momentum acceptance (MA) was statistically analyzed based on one design of the High Energy Photon Source (HEPS). It was found that the probability of MA reduction due to crossing of half integer resonances is closely correlated with the level of beta beats at the nominal tunes, but independent of the error sources. The analysis indicated that for the presented HEPS lattice design, the rms amplitude of beta beats should be kept below 1.5% horizontally and 2.5% vertically to reach a small MA reduction probability of about 1%.

  4. Abnormally High Content of Free Glucosamine Residues Identified in a Preparation of Commercially Available Porcine Intestinal Heparan Sulfate

    PubMed Central

    2016-01-01

    Heparan sulfate (HS) polysaccharides are ubiquitous in animal tissues as components of proteoglycans, and they participate in many important biological processes. HS carbohydrate chains are complex and can contain rare structural components such as N-unsubstituted glucosamine (GlcN). Commercially available HS preparations have been invaluable in many types of research activities. In the course of preparing microarrays to include probes derived from HS oligosaccharides, we found an unusually high content of GlcN residue in a recently purchased batch of porcine intestinal mucosal HS. Composition and sequence analysis by mass spectrometry of the oligosaccharides obtained after heparin lyase III digestion of the polysaccharide indicated two and three GlcN in the tetrasaccharide and hexasaccharide fractions, respectively. 1H NMR of the intact polysaccharide showed that this unusual batch differed strikingly from other HS preparations obtained from bovine kidney and porcine intestine. The very high content of GlcN (30%) and low content of GlcNAc (4.2%) determined by disaccharide composition analysis indicated that N-deacetylation and/or N-desulfation may have taken place. HS is widely used by the scientific community to investigate HS structures and activities. Great care has to be taken in drawing conclusions from investigations of structural features of HS and specificities of HS interaction with proteins when commercial HS is used without further analysis. Pending the availability of a validated commercial HS reference preparation, our data may be useful to members of the scientific community who have used the present preparation in their studies. PMID:27295282

  5. Simulation of High Velocity Impact on Composite Structures - Model Implementation and Validation

    NASA Astrophysics Data System (ADS)

    Schueler, Dominik; Toso-Pentecôte, Nathalie; Voggenreiter, Heinz

    2016-08-01

    High velocity impact on composite aircraft structures leads to the formation of flexural waves that can cause severe damage to the structure. Damage and failure can occur within the plies and/or in the resin rich interface layers between adjacent plies. In the present paper a modelling methodology is documented that captures intra- and inter-laminar damage and their interrelations by use of shell element layers representing sub-laminates that are connected with cohesive interface layers to simulate delamination. This approach allows the simulation of large structures while still capturing the governing damage mechanisms and their interactions. The paper describes numerical algorithms for the implementation of a Ladevèze continuum damage model for the ply and methods to derive input parameters for the cohesive zone model. By comparison with experimental results from gas gun impact tests the potential and limitations of the modelling approach are discussed.

  6. Integrated State Estimation and Contingency Analysis Software Implementation using High Performance Computing Techniques

    SciTech Connect

    Chen, Yousu; Glaesemann, Kurt R.; Rice, Mark J.; Huang, Zhenyu

    2015-12-31

    Power system simulation tools are traditionally developed in sequential mode and codes are optimized for single core computing only. However, the increasing complexity in the power grid models requires more intensive computation. The traditional simulation tools will soon not be able to meet the grid operation requirements. Therefore, power system simulation tools need to evolve accordingly to provide faster and better results for grid operations. This paper presents an integrated state estimation and contingency analysis software implementation using high performance computing techniques. The software is able to solve large size state estimation problems within one second and achieve a near-linear speedup of 9,800 with 10,000 cores for contingency analysis application. The performance evaluation is presented to show its effectiveness.

  7. Design and implementation of a high frequency electrical impedance tomography system.

    PubMed

    Halter, Ryan; Hartov, Alex; Paulsen, Keith D

    2004-02-01

    Electrical impedance tomography is an imaging modality being investigated for use in detection of breast cancer. Use of higher frequencies than have typically been employed may benefit the detection processes. In this current work we discuss the design and initial implementation of a system having a bandwidth of 10 MHz. Previous investigations into high frequency designs have proven more difficult than anticipated and shown that careful selection of systems architecture is critical to achieving broadband performance above 1 MHz. The design for this new system is based on a digital signal processor (DSP) which is used for control, signal generation and signal processing. Signal generation and detection, software design and preliminary system specifications are discussed.

  8. LS-DYNA Implementation of Polymer Matrix Composite Model Under High Strain Rate Impact

    NASA Technical Reports Server (NTRS)

    Zheng, Xia-Hua; Goldberg, Robert K.; Binienda, Wieslaw K.; Roberts, Gary D.

    2003-01-01

    A recently developed constitutive model is implemented into LS-DYNA as a user defined material model (UMAT) to characterize the nonlinear strain rate dependent behavior of polymers. By utilizing this model within a micromechanics technique based on a laminate analogy, an algorithm to analyze the strain rate dependent, nonlinear deformation of a fiber reinforced polymer matrix composite is then developed as a UMAT to simulate the response of these composites under high strain rate impact. The models are designed for shell elements in order to ensure computational efficiency. Experimental and numerical stress-strain curves are compared for two representative polymers and a representative polymer matrix composite, with the analytical model predicting the experimental response reasonably well.

  9. Highly Efficient Long-Distance Quantum Communication: a Blueprint for Implementation

    NASA Astrophysics Data System (ADS)

    Li, Linshu; Muralidharan, Sreraman; Kim, Jungsang; Lutkenhaus, Norbert; Lukin, Mikhail; Jiang, Liang

    2015-03-01

    Quantum repeaters provide a way for long distance quantum communication through optical fiber networks. Transmission losses and operation errors are two major challenges to the implementation of quantum repeaters. At each intermediate repeater station, transmission losses can be overcome using either heralded entanglement generation or quantum error correction, while operation errors can be corrected via entanglement purification or quantum error correction. Depending on the mechanisms used to correct loss and operation errors respectively, three generations of quantum repeaters have been proposed. We present a quantitative comparison of different quantum repeater schemes by evaluating the time- and qubit-resource consumed simultaneously. We can identify the most efficient scheme for given technological capabilities, which are characterized by fiber coupling efficiency, local gate fidelity, and local gate speed. Our work provides a roadmap for high-speed quantum networks across continental distances. Linshu and Sreraman contributed equally to this work.

  10. High-throughput imaging and analysis of root system architecture in Brachypodium distachyon under differential nutrient availability

    PubMed Central

    Ingram, Paul A.; Zhu, Jinming; Shariff, Aabid; Davis, Ian W.; Benfey, Philip N.; Elich, Tedd

    2012-01-01

    Nitrogen (N) and phosphorus (P) deficiency are primary constraints for plant productivity, and root system architecture (RSA) plays a vital role in the acquisition of these nutrients. The genetic determinants of RSA are poorly understood, primarily owing to the complexity of crop genomes and the lack of sufficient RSA phenotyping methods. The objective of this study was to characterize the RSA of two Brachypodium distachyon accessions under different nutrient availability. To do so, we used a high-throughput plant growth and imaging platform, and developed software that quantified 19 different RSA traits. We found significant differences in RSA between two Brachypodium accessions grown on nutrient-rich, low-N and low-P conditions. More specifically, one accession maintained axile root growth under low N, while the other accession maintained lateral root growth under low P. These traits resemble the RSA of crops adapted to low-N and -P conditions, respectively. Furthermore, we found that a number of these traits were highly heritable. This work lays the foundation for future identification of important genetic components of RSA traits under nutrient limitation using a mapping population derived from these two accessions. PMID:22527399

  11. High-throughput imaging and analysis of root system architecture in Brachypodium distachyon under differential nutrient availability.

    PubMed

    Ingram, Paul A; Zhu, Jinming; Shariff, Aabid; Davis, Ian W; Benfey, Philip N; Elich, Tedd

    2012-06-05

    Nitrogen (N) and phosphorus (P) deficiency are primary constraints for plant productivity, and root system architecture (RSA) plays a vital role in the acquisition of these nutrients. The genetic determinants of RSA are poorly understood, primarily owing to the complexity of crop genomes and the lack of sufficient RSA phenotyping methods. The objective of this study was to characterize the RSA of two Brachypodium distachyon accessions under different nutrient availability. To do so, we used a high-throughput plant growth and imaging platform, and developed software that quantified 19 different RSA traits. We found significant differences in RSA between two Brachypodium accessions grown on nutrient-rich, low-N and low-P conditions. More specifically, one accession maintained axile root growth under low N, while the other accession maintained lateral root growth under low P. These traits resemble the RSA of crops adapted to low-N and -P conditions, respectively. Furthermore, we found that a number of these traits were highly heritable. This work lays the foundation for future identification of important genetic components of RSA traits under nutrient limitation using a mapping population derived from these two accessions.

  12. [Not Available].

    PubMed

    Demaeyer, Ph

    2016-01-01

    Medicine owes many to Hippocrate, but pneumology traces its origin back to antiquity, from Mesopotamia to ancient Rome. Regarding prehistory: if viscera of this period have not been kept, some bones were. Since Neanderthals, it is then possible to study osteoarticular pathologies (often chronic arthrosis). But no evidence of tuberculosis was found (all thoracic kyphosis are not tuberculosis). Tuberculosis probably appears during the Neolithic age, because of high concentration of population. In ancient times, pneumology was of course not a real medical specialty. However, respiratory illness already constituted a big part of antique medical practice. The purpose of the physician in antiquity was to establish a diagnosis, a prognostic and to propose a treatment. Prognostic revealed to be of great importance in ancient times, since therapeutic efficacy was limited. Contemporary physicians often neglect this part of their practice. In ancient times, physicians also tried to gradually eliminate magic-religious aspects in taking care of the patients. This review will propose a journey from Mesopotamia to ancient Egypt (and its medical papyrus). Very few sources are available concerning medicine in pre-Columbian cultures. However, it is well known that shamans had, besides their religious competences, a great pharmacopoeia. Because of these very few sources, this topic will not be added to this article. Little is known in Europa about chinese medicine before the Jesuit mission in China during the 17th and 18th centuries. Yet, chinese medicine grew in parallel with European's one. Some relevant elements of this medicine will hereafter be shown.

  13. [Not Available].

    PubMed

    Bentué-Ferrer, Danièle; Tribut, Olivier; Verdier, Marie-Clémence; Debruyne, Danièle

    2010-01-01

    Clobazam is a 1,5 benzodiazepine available in France since 1975, used in add-on with the other anticonvulsant drugs in the treatment of refractory epilepsies of child and adult and for the treatment of anxiety of adult. It is mainly metabolized in desmethylclobazam, or norclobazam, active metabolite, present in a concentration approximately eight times superior to that of the parent drug, but with an activity of the order of 20 to 40% of that of clobazam. Elimination half-life of clobazam is of 18 h while that of norclobazam is from 40 to 50 h. There is a large interindividual variability in the plasma concentrations. Furthermore, clobazam being prescribed in add-on with the other anticonvulsant drugs in resistant epilepsies, concentration-effect relationship is difficult to bring to light, since, in many studies, the patients who did not answer received the highest doses. Adverse reactions are moderated, appearing more often for the highest concentrations; also the phenomenon of tolerance seems more frequent in high concentrations. However, because of the kinetic interactions, a dosage of clobazam and norclobazam can be useful in certain cases. There is no validated therapeutic range, but the usual concentrations are in the range of 100-300 μg/L for the parent drug and about ten times more for the metabolite. The level of proof of the interest of the Therapeutic Drug Monitoring for this molecule is estimated in: rather useless.

  14. Sphagnum-dominated bog systems are highly effective yet variable sources of bio-available iron to marine waters.

    PubMed

    Krachler, Regina; Krachler, Rudolf F; Wallner, Gabriele; Steier, Peter; El Abiead, Yasin; Wiesinger, Hubert; Jirsa, Franz; Keppler, Bernhard K

    2016-06-15

    Iron is a micronutrient of particular interest as low levels of iron limit primary production of phytoplankton and carbon fluxes in extended regions of the world's oceans. Sphagnum-peatland runoff is extraordinarily rich in dissolved humic-bound iron. Given that several of the world's largest wetlands are Sphagnum-dominated peatlands, this ecosystem type may serve as one of the major sources of iron to the ocean. Here, we studied five near-coastal creeks in North Scotland using freshwater/seawater mixing experiments of natural creek water and synthetic seawater based on a (59)Fe radiotracer technique combined with isotopic characterization of dissolved organic carbon by Accelerator Mass Spectrometry. Three of the creeks meander through healthy Sphagnum-dominated peat bogs and the two others through modified peatlands which have been subject to artificial drainage for centuries. The results revealed that, at the time of sampling (August 16-24, 2014), the creeks that run through modified peatlands delivered 11-15μg iron per liter creek water to seawater, whereas the creeks that run through intact peatlands delivered 350-470μg iron per liter creek water to seawater. To find out whether this humic-bound iron is bio-available to marine algae, we performed algal growth tests using the unicellular flagellated marine prymnesiophyte Diacronema lutheri and the unicellular marine green alga Chlorella salina, respectively. In both cases, the riverine humic material provided a highly bio-available source of iron to the marine algae. These results add a new item to the list of ecosystem services of Sphagnum-peatlands.

  15. Line manager implementation perceptions as a mediator of relations between high-performance work practices and employee outcomes.

    PubMed

    Sikora, David M; Ferris, Gerald R; Van Iddekinge, Chad H

    2015-11-01

    Strategic human resources management (SHRM) scholars recently have suggested that high-performance work practices (HPWP) implementation might serve as a critical mediator between HPWP and workplace outcomes. This study proposes and tests a model that positions line managers' perceptions regarding the extent to which they implement their organization's HPWP as a mediator of relations between HPWP and employee attitudes (i.e., turnover intentions and participative decision-making perceptions) and behavior (i.e., job performance). Using data from 507 line managers and 109 matched line manager-subordinate response sets, the results suggest that line managers' HPWP implementation perceptions fully mediate relations between HPWP and employee outcomes. The authors also found that line managers' human resources competency and political skill affect their HPWP implementation perceptions. Overall, these findings contribute to a more informed understanding of relationships between HPWP and work outcomes and suggest that additional SHRM research is needed to better understand whether and how HPWP are implemented.

  16. High Availability Applications for NOMADS at the NOAA Web Operations Center Aimed at Providing Reliable Real Time Access to Operational Model Data

    NASA Astrophysics Data System (ADS)

    Alpert, J. C.; Rutledge, G.; Wang, J.; Freeman, P.; Kang, C. Y.

    2009-05-01

    The NOAA Operational Modeling Archive Distribution System (NOMADS) is now delivering high availability services as part of NOAA's official real time data dissemination at its Web Operations Center (WOC). The WOC is a web service used by all organizational units in NOAA and acts as a data repository where public information can be posted to a secure and scalable content server. A goal is to foster collaborations among the research and education communities, value added retailers, and public access for science and development efforts aimed at advancing modeling and GEO-related tasks. The services used to access the operational model data output are the Open-source Project for a Network Data Access Protocol (OPeNDAP), implemented with the Grid Analysis and Display System (GrADS) Data Server (GDS), and applications for slicing, dicing and area sub-setting the large matrix of real time model data holdings. This approach insures an efficient use of computer resources because users transmit/receive only the data necessary for their tasks including metadata. Data sets served in this way with a high availability server offer vast possibilities for the creation of new products for value added retailers and the scientific community. New applications to access data and observations for verification of gridded model output, and progress toward integration with access to conventional and non-conventional observations will be discussed. We will demonstrate how users can use NOMADS services to repackage area subsets either using repackaging of GRIB2 files, or values selected by ensemble component, (forecast) time, vertical levels, global horizontal location, and by variable, virtually a 6- Dimensional analysis services across the internet.

  17. Design and implementation of a high sensitivity fully integrated passive UHF RFID tag

    NASA Astrophysics Data System (ADS)

    Shoucheng, Li; Xin'an, Wang; Ke, Lin; Jinpeng, Shen; Jinhai, Zhang

    2014-10-01

    A fully integrated passive UHF RFID tag complying with the ISO18000-6B protocol is presented, which includes an analog front-end, a baseband processor, and an EEPROM memory. To extend the communication range, a high efficiency differential-drive CMOS rectifier is adopted. A novel high performance voltage limiter is used to provide a stable limiting voltage, with a 172 mV voltage variation against temperature variation and process dispersion. The dynamic band-enhancement technique is used in the regulator circuit to improve the regulating capacity. A rail-to-rail hysteresis comparator is adopted to demodulate the signal correctly in any condition. The whole transponder chip is implemented in a 0.18 μm CMOS process, with a die size of 900 × 800 μm2. Our measurement results show that the total power consumption of the tag chip is only 6.8 μW, with a sensitivity of -13.5 dBm

  18. Hardware Implementation of 32-Bit High-Speed Direct Digital Frequency Synthesizer

    PubMed Central

    Ibrahim, Salah Hasan; Ali, Sawal Hamid Md.; Islam, Md. Shabiul

    2014-01-01

    The design and implementation of a high-speed direct digital frequency synthesizer are presented. A modified Brent-Kung parallel adder is combined with pipelining technique to improve the speed of the system. A gated clock technique is proposed to reduce the number of registers in the phase accumulator design. The quarter wave symmetry technique is used to store only one quarter of the sine wave. The ROM lookup table (LUT) is partitioned into three 4-bit sub-ROMs based on angular decomposition technique and trigonometric identity. Exploiting the advantages of sine-cosine symmetrical attributes together with XOR logic gates, one sub-ROM block can be removed from the design. These techniques, compressed the ROM into 368 bits. The ROM compressed ratio is 534.2 : 1, with only two adders, two multipliers, and XOR-gates with high frequency resolution of 0.029 Hz. These techniques make the direct digital frequency synthesizer an attractive candidate for wireless communication applications. PMID:24991635

  19. Dataflow-Based Implementation of Layered Sensing Applications on High-Performance Embedded Processors

    DTIC Science & Technology

    2013-03-01

    GPUs , based on the Compute Unified Device Architecture ( CUDA ) programming framework [11]. Since CUDA is a C-like programming language, CUDA can be... CUDA -targeted actor for GPU -based implementation: module CUDA sift_descriptor_r output output1 sift token output output2 sift token output...comparison for the CPU-targeted actors (implemented using C) and GPU -targeted actors (implemented using CUDA ) in the targeted image registration application

  20. Neural network controller development and implementation for spark ignition engines with high EGR levels.

    PubMed

    Vance, Jonathan Blake; Singh, Atmika; Kaul, Brian C; Jagannathan, Sarangapani; Drallmeier, James A

    2007-07-01

    Past research has shown substantial reductions in the oxides of nitrogen (NOx) concentrations by using 10%-25% exhaust gas recirculation (EGR) in spark ignition (SI) engines (see Dudek and Sain, 1989). However, under high EGR levels, the engine exhibits strong cyclic dispersion in heat release which may lead to instability and unsatisfactory performance preventing commercial engines to operate with high EGR levels. A neural network (NN)-based output feedback controller is developed to reduce cyclic variation in the heat release under high levels of EGR even when the engine dynamics are unknown by using fuel as the control input. A separate control loop was designed for controlling EGR levels. The stability analysis of the closed-loop system is given and the boundedness of the control input is demonstrated by relaxing separation principle, persistency of excitation condition, certainty equivalence principle, and linear in the unknown parameter assumptions. Online training is used for the adaptive NN and no offline training phase is needed. This online learning feature and model-free approach is used to demonstrate the applicability of the controller on a different engine with minimal effort. Simulation results demonstrate that the cyclic dispersion is reduced significantly using the proposed controller when implemented on an engine model that has been validated experimentally. For a single cylinder research engine fitted with a modern four-valve head (Ricardo engine), experimental results at 15% EGR indicate that cyclic dispersion was reduced 33% by the controller, an improvement of fuel efficiency by 2%, and a 90% drop in NOx from stoichiometric operation without EGR was observed. Moreover, unburned hydrocarbons (uHC) drop by 6% due to NN control as compared to the uncontrolled scenario due to the drop in cyclic dispersion. Similar performance was observed with the controller on a different engine.

  1. Real-Time Kennedy Space Center and Cape Canaveral Air Force Station High-Resolution Model Implementation and Verification

    NASA Technical Reports Server (NTRS)

    Shafer, Jaclyn; Watson, Leela R.

    2015-01-01

    NASA's Launch Services Program, Ground Systems Development and Operations, Space Launch System and other programs at Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS) use the daily and weekly weather forecasts issued by the 45th Weather Squadron (45 WS) as decision tools for their day-to-day and launch operations on the Eastern Range (ER). Examples include determining if they need to limit activities such as vehicle transport to the launch pad, protect people, structures or exposed launch vehicles given a threat of severe weather, or reschedule other critical operations. The 45 WS uses numerical weather prediction models as a guide for these weather forecasts, particularly the Air Force Weather Agency (AFWA) 1.67 km Weather Research and Forecasting (WRF) model. Considering the 45 WS forecasters' and Launch Weather Officers' (LWO) extensive use of the AFWA model, the 45 WS proposed a task at the September 2013 Applied Meteorology Unit (AMU) Tasking Meeting requesting the AMU verify this model. Due to the lack of archived model data available from AFWA, verification is not yet possible. Instead, the AMU proposed to implement and verify the performance of an ER version of the high-resolution WRF Environmental Modeling System (EMS) model configured by the AMU (Watson 2013) in real time. Implementing a real-time version of the ER WRF-EMS would generate a larger database of model output than in the previous AMU task for determining model performance, and allows the AMU more control over and access to the model output archive. The tasking group agreed to this proposal; therefore the AMU implemented the WRF-EMS model on the second of two NASA AMU modeling clusters. The AMU also calculated verification statistics to determine model performance compared to observational data. Finally, the AMU made the model output available on the AMU Advanced Weather Interactive Processing System II (AWIPS II) servers, which allows the 45 WS and AMU staff to customize

  2. [Not Available].

    PubMed

    Pecevski, Dejan; Natschläger, Thomas; Schuch, Klaus

    2009-01-01

    The Parallel Circuit SIMulator (PCSIM) is a software package for simulation of neural circuits. It is primarily designed for distributed simulation of large scale networks of spiking point neurons. Although its computational core is written in C++, PCSIM's primary interface is implemented in the Python programming language, which is a powerful programming environment and allows the user to easily integrate the neural circuit simulator with data analysis and visualization tools to manage the full neural modeling life cycle. The main focus of this paper is to describe PCSIM's full integration into Python and the benefits thereof. In particular we will investigate how the automatically generated bidirectional interface and PCSIM's object-oriented modular framework enable the user to adopt a hybrid modeling approach: using and extending PCSIM's functionality either employing pure Python or C++ and thus combining the advantages of both worlds. Furthermore, we describe several supplementary PCSIM packages written in pure Python and tailored towards setting up and analyzing neural simulations.

  3. High water availability increases the negative impact of a native hemiparasite on its non-native host

    PubMed Central

    Cirocco, Robert M.; Facelli, José M.; Watling, Jennifer R.

    2016-01-01

    Environmental factors alter the impacts of parasitic plants on their hosts. However, there have been no controlled studies on how water availability modulates stem hemiparasites’ effects on hosts. A glasshouse experiment was conducted to investigate the association between the Australian native stem hemiparasite Cassytha pubescens and the introduced host Ulex europaeus under high (HW) and low (LW) water supply. Cassytha pubescens had a significant, negative effect on the total biomass of U. europaeus, which was more severe in HW than LW. Regardless of watering treatment, infection significantly decreased shoot and root biomass, nodule biomass, nodule biomass per unit root biomass, F v/F m, and nitrogen concentration of U. europaeus. Host spine sodium concentration significantly increased in response to infection in LW but not HW conditions. Host water potential was significantly higher in HW than in LW, which may have allowed the parasite to maintain higher stomatal conductances in HW. In support of this, the δ13C of the parasite was significantly lower in HW than in LW (and significantly higher than the host). C. pubescens also had significantly higher F v/F m and 66% higher biomass per unit host in the HW compared with the LW treatment. The data suggest that the enhanced performance of C. pubescens in HW resulted in higher parasite growth rates and thus a larger demand for resources from the host, leading to poorer host performance in HW compared with LW. C. pubescens should more negatively affect U. europaeus growth under wet conditions rather than under dry conditions in the field. PMID:26703920

  4. An Ethnographic Policy Analysis of a Michigan High School's Implementation of State-Mandated Universal College Preparatory Curricula

    ERIC Educational Resources Information Center

    Bair, David E.; Bair, Mary Antony

    2011-01-01

    Although many states mandate college preparatory curricula for all high school students, there is no conclusive evidence regarding the benefits of this effort. Furthermore, we know little about how schools interpret and implement such policies. This extended ethnographic case study included a 4 year examination of 1 Michigan high school's response…

  5. The Implementation of Cooperative Learning in English Class of Favorite School of Secondary High School 5 Batusangkar, West Sumatera

    ERIC Educational Resources Information Center

    Kristiawan, Muhammad

    2013-01-01

    The aim of this research is to explain the implementation of cooperative learning in English class of favorite school of Secondary High School 5 Batusangkar, West Sumatera; to find out the achievement of Cooperative Learning in English class of Favorite School of Secondary High School 5 Batusangkar, West Sumatera; and to know how is the strengths…

  6. Implementing an Additive, College Access and Readiness Program for Latina/o High School Students in the U.S.

    ERIC Educational Resources Information Center

    Amaro-Jimenez, Carla; Hungerford-Kresser, Holly

    2013-01-01

    In this article we draw on the experiences of a diverse group of 34 first-generation college students, collected over a year, who served as peer mentors to minority and Latina/o high school students enrolled in four Title I (low-income) high schools in the Southwest U.S. The article identifies the successes and challenges of implementing an…

  7. [Not Available].

    PubMed

    1992-03-25

    Archersstar Sudha Bhuchar, right, launches a video on breast screening for women from ethnic minorities, sponsored by the NHS. The video is available in six languages. Ms Bhuchar is pictured with programme co-ordinator Julietta Patrick.

  8. Design and implementation of a simple multinuclear MRI system for ultra high-field imaging of animals

    NASA Astrophysics Data System (ADS)

    Choi, Chang-Hoon; Ha, YongHyun; Veeraiah, Pandichelvam; Felder, Jörg; Möllenhoff, Klaus; Shah, N. Jon

    2016-12-01

    Non-proton MRI has recently garnered gathering interest with the increased availability of ultra high-field MRI system. Assuming the availability of a broadband RF amplifier, performing multinuclear MR experiments essentially requires additional hardware, such as an RF resonator and a T/R switch for each nucleus. A double- or triple-resonant RF probe is typically constructed using traps or PIN-diode circuits, but this approach degrades the signal-to-noise ratio (SNR) and image quality compared to a single-resonant coil and this is a limiting factor. In this work, we have designed the required hardware for multinuclear MR imaging experiments employing six single-resonant coil sets and a purpose-built animal bed; these have been implemented into a home-integrated 9.4 T preclinical MRI scanner. System capabilities are demonstrated by distinguishing concentration differences and sensitivity of X-nuclei imaging and spectroscopy without SNR penalty for any nuclei, no subject interruption and no degradation of the static shim conditions.

  9. Implementation of High-Dose-Rate Brachytherapy and Androgen Deprivation in Patients With Prostate Cancer

    SciTech Connect

    Lilleby, Wolfgang; Tafjord, Gunnar; Raabe, Nils K.

    2012-07-01

    Purpose: To evaluate outcome (overall survival [OS], the actuarial 5-year cancer-specific survival [CSS], disease-free survival [DFS], biochemical failure-free survival [BFS]), complications and morbidity in patients treated with high-dose-rate brachytherapy (HDR-BT) boost and hormonal treatment with curative aims. Methods: Between 2004 and 2009, 275 prospectively followed pN0/N0M0 patients were included: 19 patients (7%) with T2, Gleason score 7 and prostate-specific antigen (PSA) <10 and 256 patients (93%) with T3 or Gleason score 8-10 or PSA >20 received multimodal treatment with conformal four-field radiotherapy (prostate/vesiculae 2 Gy Multiplication-Sign 25) combined with HDR-BT (iridium 192; prostate 10 Gy Multiplication-Sign 2) with long-term androgen deprivation therapy (ADT). Results: After a median observation time of 44.2 months (range, 10.4-90.5 months) 12 patients had relapsed clinically and/or biochemically and 10 patients were dead, of which 2 patients died from prostate cancer. Five-year estimates of BFS, CSS, DFS, and OS rates were 98.5%, 99.3%, 95.6%, and 96.3%, respectively. None of the patients with either Gleason score <8 or with intermediate risk profile had relapsed. The number of HDR-BT treatments was not related to outcome. Despite of age (median, 65.7 years; range, 45.7-77 years) and considerable pretreatment comorbidity in 39 of 275 patients, Genitourinary treatment-related morbidity was moderate with long-lasting Radiation Therapy Oncology Group Grade 2 voiding problems in 26 patients (9.5%) and occasionally mucous discharge in 20 patients (7%), none with Grade >2 for gastrointestinal at follow-up. Complications during implantations were related to pubic arch interference (4 patients) and lithotomy time, causing 2 patients to develop compartment syndrome. Conclusion: Despite still preliminary observations, our 5-year outcome estimates favor the implementation of high-dose-rate brachytherapy in high-risk patients combined with conformal

  10. Ripple FPN reduced algorithm based on temporal high-pass filter and hardware implementation

    NASA Astrophysics Data System (ADS)

    Li, Yiyang; Li, Shuo; Zhang, Zhipeng; Jin, Weiqi; Wu, Lei; Jin, Minglei

    2016-11-01

    Cooled infrared detector arrays always suffer from undesired Ripple Fixed-Pattern Noise (FPN) when observe the scene of sky. The Ripple Fixed-Pattern Noise seriously affect the imaging quality of thermal imager, especially for small target detection and tracking. It is hard to eliminate the FPN by the Calibration based techniques and the current scene-based nonuniformity algorithms. In this paper, we present a modified space low-pass and temporal high-pass nonuniformity correction algorithm using adaptive time domain threshold (THP&GM). The threshold is designed to significantly reduce ghosting artifacts. We test the algorithm on real infrared in comparison to several previously published methods. This algorithm not only can effectively correct common FPN such as Stripe, but also has obviously advantage compared with the current methods in terms of detail protection and convergence speed, especially for Ripple FPN correction. Furthermore, we display our architecture with a prototype built on a Xilinx Virtex-5 XC5VLX50T field-programmable gate array (FPGA). The hardware implementation of the algorithm based on FPGA has two advantages: (1) low resources consumption, and (2) small hardware delay (less than 20 lines). The hardware has been successfully applied in actual system.

  11. Astronomy Education in Morocco - New Project for Implementing Astronomy in High Schools

    NASA Astrophysics Data System (ADS)

    Darhmaoui, H.; Loudiyi, K.

    2006-08-01

    Astronomy education in Morocco, like in many developing countries, is not well developed and lacks the very basics in terms of resources, facilities and research. In 2004, the International Astronomical Union (IAU) signed an agreement of collaboration with Al Akhawayn University in Ifrane to support the continued, long-term development of astronomy and astrophysics in Morocco. This is within the IAU program "Teaching for Astronomy Development" (TAD). The initial focus of the program concentrated exclusively on the University's Bachelor of Science degree program. Within this program, and during two years, we were successful in providing adequate astronomy training to our physics faculty and few of our engineering students. We also offered our students and community general astronomy background through courses, invited talks and extra curricular activities. The project is now evolving towards a wider scope and seeks promoting astronomy education at the high school level. It is based on modules from the Hands on Universe (HOU) interactive astronomy program. Moroccan students will engage in doing observational astronomy from their PCs. They will have access to a world wide network of telescopes and will interact with their peers abroad. Through implementing astronomy education at this lower age, we foresee an increasing interest among our youth not only in astronomy but also in physics, mathematics, and technology. The limited astronomy resources, the lack of teachers experience in the field and the language barrier are amongst the difficulties that we'll be facing in achieving the objectives of this new program.

  12. Implementation of tetra-poly(ethylene glycol) hydrogel with high mechanical strength into microfluidic device technology

    PubMed Central

    Takehara, Hiroaki; Nagaoka, Akira; Noguchi, Jun; Akagi, Takanori; Sakai, Takamasa; Chung, Ung-il; Kasai, Haruo; Ichiki, Takanori

    2013-01-01

    Hydrogels have several excellent characteristics suitable for biomedical use such as softness, biological inertness and solute permeability. Hence, integrating hydrogels into microfluidic devices is a promising approach for providing additional functions such as biocompatibility and porosity, to microfluidic devices. However, the poor mechanical strength of hydrogels has severely limited device design and fabrication. A tetra-poly(ethylene glycol) (tetra-PEG) hydrogel synthesized recently has high mechanical strength and is expected to overcome such a limitation. In this research, we have comprehensively studied the implementation of tetra-PEG gel into microfluidic device technology. First, the fabrication of tetra-PEG gel/PDMS hybrid microchannels was established by developing a simple and robust bonding technique. Second, some fundamental features of tetra-PEG gel/PDMS hybrid microchannels, particularly fluid flow and mass transfer, were studied. Finally, to demonstrate the unique application of tetra-PEG-gel-integrated microfluidic devices, the generation of patterned chemical modulation with the maximum concentration gradient: 10% per 20 μm in a hydrogel was performed. The techniques developed in this study are expected to provide fundamental and beneficial methods of developing various microfluidic devices for life science and biomedical applications. PMID:24404072

  13. Implementation of Ultrasonic Sensing for High Resolution Measurement of Binary Gas Mixture Fractions

    PubMed Central

    Bates, Richard; Battistin, Michele; Berry, Stephane; Bitadze, Alexander; Bonneau, Pierre; Bousson, Nicolas; Boyd, George; Bozza, Gennaro; Crespo-Lopez, Olivier; Riva, Enrico Da; Degeorge, Cyril; Deterre, Cecile; DiGirolamo, Beniamino; Doubek, Martin; Favre, Gilles; Godlewski, Jan; Hallewell, Gregory; Hasib, Ahmed; Katunin, Sergey; Langevin, Nicolas; Lombard, Didier; Mathieu, Michel; McMahon, Stephen; Nagai, Koichi; Pearson, Benjamin; Robinson, David; Rossi, Cecilia; Rozanov, Alexandre; Strauss, Michael; Vitek, Michal; Vacek, Vaclav; Zwalinski, Lukasz

    2014-01-01

    We describe an ultrasonic instrument for continuous real-time analysis of the fractional mixture of a binary gas system. The instrument is particularly well suited to measurement of leaks of a high molecular weight gas into a system that is nominally composed of a single gas. Sensitivity < 5 × 10−5 is demonstrated to leaks of octaflouropropane (C3F8) coolant into nitrogen during a long duration (18 month) continuous study. The sensitivity of the described measurement system is shown to depend on the difference in molecular masses of the two gases in the mixture. The impact of temperature and pressure variances on the accuracy of the measurement is analysed. Practical considerations for the implementation and deployment of long term, in situ ultrasonic leak detection systems are also described. Although development of the described systems was motivated by the requirements of an evaporative fluorocarbon cooling system, the instrument is applicable to the detection of leaks of many other gases and to processes requiring continuous knowledge of particular binary gas mixture fractions. PMID:24961217

  14. High-resolution Global Crop Simulation Design and Implementation for Sustainability and Climate Change Analysis

    NASA Astrophysics Data System (ADS)

    Kang, S.; Kline, K.; Post, W.; Nichols, J.; Nair, S.; Singh, N.; Wang, D.; Wullschleger, S. D.; Izaurralde, R. C.

    2012-12-01

    International communities seek expanded understanding of the land use change issues associated with food and bioenergy production, and climate change; however, the existing assessments of large-scale deployment, utilization, and sustainability of crop production systems are insufficiently quantitative at the global scale. To undertake this broad analysis of large-scale crop production, an analysis framework to meet the challenges with a regionally and globally distributed agroecosystem model is needed. We designed a global modeling platform of crop production, consisting of five major components: (i) standardized global natural resources and management databases, ii) global simulation unit and management scenarios, iii) model calibration and validation, iv) high-performance computing (HPC) modeling, and v) simulation output processing and analysis. A case study with the HPC-EPIC model and a perennial bioenergy crop, switchgrass (Panicum virgatum L.) and global biomass productivity analysis on grassland was conducted to demonstrate the application of this platform. The results indicated that this modeling platform was effective to catch global productivity variability of switchgrass and applicable for the global analysis of crop production and sustainability. Future efforts include enhancing the databases of crops and implementing global simulations for various crops and studying impacts, adaptation and vulnerability of climate change. We anticipated this platform to provide effective tools and assessment data for international communities to conduct global analysis of crop production and sustainability associated with climate change issues.

  15. Implementation of a Noise Mitigation Strategy for a High-Pressure Xenon Detector

    SciTech Connect

    Seifert, Allen; Milbrath, Brian D.; Pitts, W. K.; Smith, Leon E.

    2005-10-23

    High-pressure xenon (HPXe) detectors have historically been unable to achieve or even approach the theoretically predicted energy resolution, a phenomenon usually attributed to problems with microphonic, vibrational, or acoustic noise. All these noises are expected to have characteristic frequency signatures. We have determined the effects of external acoustic noise signals on the resolution of HPXe spectrometers and implemented a technique to reduce or eliminate the resolution loss caused by external acoustic noise in real time. Using a precision waveform generator as the driver on a 400-watt speaker, we determined the response of a commercial HPXe detector to a variety of constant frequency acoustic noise signals by performing a fast Fourier transform on a buffered detector output signal and noting distortions to the spectral response of the frequency domain. A data acquisition package was developed using the frequency response information to perform real time digital signal noise filtering on each gamma-ray pulse. With external acoustic noise, the measured resolution of HPXe gamma-ray energy spectra was degraded by a factor of 2 to 3. With the noise mitigating data acquisition package the spectroscopic resolution was restored to values comparable to the resolution measured under ideal (non-noisy) conditions.

  16. Analog Exercise Hardware to Implement a High Intensity Exercise Program During Bed Rest

    NASA Technical Reports Server (NTRS)

    Loerch, Linda; Newby, Nate; Ploutz-Snyder, Lori

    2012-01-01

    Background: In order to evaluate novel countermeasure protocols in a space flight analog prior to validation on the International Space Station (ISS), NASA's Human Research Program (HRP) is sponsoring a multi-investigator bedrest campaign that utilizes a combination of commercial and custom-made exercise training hardware to conduct daily resistive and aerobic exercise protocols. This paper will describe these pieces of hardware and how they are used to support current bedrest studies at NASA's Flight Analog Research Unit in Galveston, TX. Discussion: To implement candidate exercise countermeasure studies during extended bed rest studies the following analog hardware are being utilized: Stand alone Zero-Gravity Locomotion Simulator (sZLS) -- a custom built device by NASA, the sZLS allows bedrest subjects to remain supine as they run on a vertically-oriented treadmill (0-15 miles/hour). The treadmill includes a pneumatic subject loading device to provide variable body loading (0-100%) and a harness to keep the subject in contact with the motorized treadmill to provide a ground reaction force at their feet that is quantified by a Kistler Force Plate. Supine Cycle Ergometer -- a commercially available supine cycle ergometer (Lode, Groningen, Netherlands) is used for all cycle ergometer sessions. The ergometer has adjustable shoulder supports and handgrips to help stabilize the subject during exercise. Horizontal Squat Device (HSD) -- a custom built device by Quantum Fitness Corp (Stafford, TX), the HSD allows for squat exercises to be performed while lying in a supine position. The HSD can provide 0 to 600 pounds of force in selectable 5 lb increments, and allows hip translation in both the vertical and horizontal planes. Prone Leg Curl -- a commercially available prone leg curl machine (Cybex International Inc., Medway, MA) is used to complete leg curl exercises. Horizontal Leg Press -- a commercially available horizontal leg press (Quantum Fitness Corporation) is

  17. Approaches in highly parameterized inversion: bgaPEST, a Bayesian geostatistical approach implementation with PEST: documentation and instructions

    USGS Publications Warehouse

    Fienen, Michael N.; D'Oria, Marco; Doherty, John E.; Hunt, Randall J.

    2013-01-01

    The application bgaPEST is a highly parameterized inversion software package implementing the Bayesian Geostatistical Approach in a framework compatible with the parameter estimation suite PEST. Highly parameterized inversion refers to cases in which parameters are distributed in space or time and are correlated with one another. The Bayesian aspect of bgaPEST is related to Bayesian probability theory in which prior information about parameters is formally revised on the basis of the calibration dataset used for the inversion. Conceptually, this approach formalizes the conditionality of estimated parameters on the specific data and model available. The geostatistical component of the method refers to the way in which prior information about the parameters is used. A geostatistical autocorrelation function is used to enforce structure on the parameters to avoid overfitting and unrealistic results. Bayesian Geostatistical Approach is designed to provide the smoothest solution that is consistent with the data. Optionally, users can specify a level of fit or estimate a balance between fit and model complexity informed by the data. Groundwater and surface-water applications are used as examples in this text, but the possible uses of bgaPEST extend to any distributed parameter applications.

  18. Graduate Student and High School Teacher Partnerships Implementing Inquiry-Based Lessons in Earth Science

    NASA Astrophysics Data System (ADS)

    Smith, M. A.; Preston, L.; Graham, K.

    2007-12-01

    Partnering science graduate students with high school teachers in their classroom is a mutually beneficial relationship. Graduate students who may become future university level faculty are exposed to teaching, classroom management, outreach scholarship, and managing time between teaching and research. Teachers benefit by having ready access to knowledgeable scientists, a link to university resources, and an additional adult in the classroom. Partnerships in Research Opportunities to Benefit Education (PROBE), a recent NSF funded GK-12 initiative, formed partnerships between science and math graduate students from the University of New Hampshire (UNH) and local high school science teachers. A primary goal of this program was to promote inquiry-based science lessons. The teacher-graduate student teams worked together approximately twenty hours per week on researching, preparing, and implementing new lessons and supervising student-led projects. Several new inquiry-based activities in Geology and Astronomy were developed as a result of collaboration between an Earth Science graduate student and high school teacher. For example, a "fishbowl" activity was very successful in sparking a classroom discussion about how minerals are used in industrial materials. The class then went on to research how to make their own paint using minerals. This activity provided a capstone project at the end of the unit about minerals, and made real world connections to the subject. A more involved geology lesson was developed focusing on the currently popular interest in forensics. Students were assigned with researching how geology can play an important part in solving a crime. When they understood the role of geologic concepts within the scope of the forensic world, they used techniques to solve their own "crime". Astronomy students were responsible for hosting and teaching middle school students about constellations, using a star- finder, and operating an interactive planetarium

  19. Available nutrients

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Biochar technology may contribute to the recovery and recycling of plant nutrients and thus add a fertilizer value to the biochar. Total nutrient content in biochars varies greatly and is mainly dependent on feedstock elemental composition and to a lesser extent on pyrolysis conditions. Availability...

  20. Research and implement on the high speed network system with CIINS based on ATM for aero manufacturing enterprise

    NASA Astrophysics Data System (ADS)

    Jiang, Zhi-qiang; Feng, Xi-lan; Zong, Xue-wen; Ding, Yu-cheng

    2005-12-01

    In this paper, the design and implementation on the high-speed network system of the Computer Integrated and Information Network System (CIINS) for aeronautical manufacturing enterprise based on ATM is explained. And designing the high-speed network, choosing the devices, network administration, and developing the network application are discussed. And also, the key technology of the network design is analyzed. The system safety is ensured, when the ATM with QoS in the main backbone network and the work team with network layer in intelligent Ethernet equipment are adapted, and a kind of firewall based on Hard-wall technology is implemented.

  1. [Not Available].

    PubMed

    Boulamery, Audrey; Venisse, Nicolas; Le Guellec, Chantal

    2011-01-01

    Teicoplanin is a glycopeptid antibiotic used for treatment of serious infections caused by Gram+ bacteriae. The treatment scheme corresponds to an initial loading dose followed by maintenance dose. High interindividual pharmacokinetic variability and strong relation between high through concentrations, dose and clinical success, support the need of therapeutic drug monitoring using through concentrations. Achieving through concentrations ≥10-15 mg/L or ≥20-40 mg/L, regarding the measurement method and the infection severity, is recommended to increase clinical success rate. The level of proof of therapeutic drug monitoring is evaluated: "necessary".

  2. 76 FR 18298 - Notice of Availability of a Final Environmental Impact Statement for the DesertXpress High-Speed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... DesertXpress High-Speed Passenger Train Project AGENCY: Federal Railroad Administration (FRA), United... the public that a Final Environmental Impact Statement (EIS) is being published for the DesertXpress High-Speed Passenger Train Project (DesertXpress project). FRA is the Lead Agency for the...

  3. Implementation of a high-resolution workstation for primary diagnosis of projection radiography images

    NASA Astrophysics Data System (ADS)

    Good, Walter F.; Herron, John M.; Maitz, Glenn S.; Gur, David; Miller, Stephen L.; Straub, William H.; Fuhrman, Carl R.

    1990-08-01

    We designed and implemented a high-resolution video workstation as the central hardware component in a comprehensive multi-project program comparing the use of digital and film modalities. The workstation utilizes a 1.8 GByte real-time disk (RCI) capable of storing 400 full-resolution images and two Tektronix (GMA251) display controllers with 19" monitors (GMA2O2). The display is configured in a portrait format with a resolution of 1536 x 2048 x 8 bit, and operates at 75 Hz in a noninterlaced mode. Transmission of data through a 12 to 8 bit lookup table into the display controllers occurs at 20 MBytes/second (.35 seconds per image). The workstation allows easy use of brightness (level) and contrast (window) to be manipulated with a trackball, and various processing options can be selected using push buttons. Display of any of the 400 images is also performed at 20MBytes/sec (.35 sec/image). A separate text display provides for the automatic display of patient history data and for a scoring form through which readers can interact with the system by means of a computer mouse. In addition, the workstation provides for the randomization of cases and for the immediate entry of diagnostic responses into a master database. Over the past year this workstation has been used for over 10,000 readings in diagnostic studies related to 1) image resolution; 2) film vs. soft display; 3) incorporation of patient history data into the reading process; and 4) usefulness of image processing.

  4. Clinical implementation of a novel applicator in high-dose-rate brachytherapy treatment of esophageal cancer

    PubMed Central

    Hansen, Jorgen L.; Bhagwat, Mandar S.; O'Farrell, Desmond A.; Friesen, Scott; Harris, Thomas C.; Damato, Antonio L.; Cormack, Robert A.; Martin, Neil E.; Devlin, Phillip M.

    2016-01-01

    Purpose In this study, we present the clinical implementation of a novel transoral balloon centering esophageal applicator (BCEA) and the initial clinical experience in high-dose-rate (HDR) brachytherapy treatment of esophageal cancer, using this applicator. Material and methods Acceptance testing and commissioning of the BCEA were performed prior to clinical use. Full performance testing was conducted including measurements of the dimensions and the catheter diameter, evaluation of the inflatable balloon consistency, visibility of the radio-opaque markers, congruence of the markers, absolute and relative accuracy of the HDR source in the applicator using the radiochromic film and source position simulator, visibility and digitization of the applicator on the computed tomography (CT) images under the clinical conditions, and reproducibility of the offset. Clinical placement of the applicator, treatment planning, treatment delivery, and patient's response to the treatment were elaborated as well. Results The experiments showed sub-millimeter accuracy in the source positioning with distal position at 1270 mm. The digitization (catheter reconstruction) was uncomplicated due to the good visibility of markers. The treatment planning resulted in a favorable dose distribution. This finding was pronounced for the treatment of the curvy anatomy of the lesion due to the improved repeatability and consistency of the delivered fractional dose to the patient, since the radioactive source was placed centrally within the lumen with respect to the clinical target due to the five inflatable balloons. Conclusions The consistency of the BCEA positioning resulted in the possibility to deliver optimized non-uniform dose along the catheter, which resulted in an increase of the dose to the cancerous tissue and lower doses to healthy tissue. A larger number of patients and long-term follow-up will be required to investigate if the delivered optimized treatment can lead to improved

  5. Understanding and implementation of hydrogen passivation of defects in string ribbon silicon for high-efficiency, manufacturable, silicon solar cells

    NASA Astrophysics Data System (ADS)

    Yelundur, Vijay

    Photovoltaics offers a unique solution to energy and environmental problems simultaneously. However, widespread application of photovoltaics will not be realized until costs are reduced by about a factor of four without sacrificing performance. Silicon crystallization and wafering account for about 55% of the photovoltaic module manufacturing cost, but can be reduced significantly if a ribbon silicon material, such as String Ribbon Si, is used as an alternative to cast Si. However, the growth of String Ribbon leads to a high density of electrically active bulk defects that limit the minority carrier lifetime and solar cell performance. The research tasks of this thesis focus on the understanding, development, and implementation of defect passivation techniques to increase the bulk carrier lifetime in String Ribbon Si in order to enhance solar cell efficiency. Hydrogen passivation of defects in Si can be performed during solar cell processing by utilizing the hydrogen available during plasma-enhanced chemical vapor deposition (PECVD) of SiNx:H films. It is shown in this thesis that hydrogen passivation of defects during the simultaneous anneal of a screen-printed A1 layer on the back and a PECVD SiNx:H film increases the bulk lifetime in String Ribbon by more than 30 mus. A three step physical model is proposed to explain the hydrogen defect passivation. Appropriate implementation of the Al-enhanced defect passivation treatment leads to String Ribbon solar cell efficiencies as high as 14.7%. Further enhancement of bulk lifetime up to 92 mus is achieved through in-situ NH3 plasma pretreatment and low-frequency (LF) plasma excitation during SiN x:H deposition followed by a rapid thermal anneal (RTA). Development of an optimized two-step RTA firing cycle for hydrogen passivation, the formation of an Al-doped back surface field, and screen-printed contact firing results in solar cell efficiencies as high as 15.6%. In the final task of this thesis, a rapid thermal

  6. [Not Available].

    PubMed

    Venisse, Nicolas; Boulamery, Audrey

    2011-01-01

    Aminoglycosides are major antibiotics indicated for the treatment of infection with gram-negative bacilli. They are characterized by high clinical effectiveness but their main drawback is the occurrence of toxicity in a significant number of patients. Pharmacokinetic parameters of aminoglycosides exhibit wide inter-individual variability and the relationships between concentration and effect have been clearly demonstrated. Consistent studies have demonstrated that therapeutic drug monitoring (TDM) of aminoglycosides administered in multiple daily doses was cost-effective in maximising antibiotic efficacy and/or reducing incidence of toxicity. Therefore TDM of aminoglycosides should be considered "essential". Level of evidence for TDM of aminoglycosides administered once daily is not so clearly demonstrated however it should be highly recommended.

  7. [Not Available].

    PubMed

    Schieveen, Pauline Gerritsen-van; Royer, Bernard

    2010-01-01

    Pharmacokinetic properties of docetaxel, an anticancer drug, are though to be interesting for therapeutic drug monitoring: high inter- and intra-variability, relationship between exposure and efficacy and especially toxicity. Moreover, the 3-weekly administration, which is the more effective scheme, is also the more toxic. However, neutropenia can be modelised and be efficiently predicted without needing plasma drug concentrations. The level evidence of therapeutic drug monitoring is thus weak regarding the possibility to adapt dose regimen without drug concentrations.

  8. Implementation of algorithms to discriminate chemical/biological airbursts from high explosive airbursts utilizing acoustic signatures

    NASA Astrophysics Data System (ADS)

    Hohil, Myron E.; Desai, Sachi; Morcos, Amir

    2006-05-01

    The Army is currently developing acoustic sensor systems that will provide extended range surveillance, detection, and identification for force protection and tactical security. A network of such sensors remotely deployed in conjunction with a central processing node (or gateway) will provide early warning and assessment of enemy threats, near real-time situational awareness to commanders, and may reduce potential hazards to the soldier. In contrast, the current detection of chemical/biological (CB) agents expelled into a battlefield environment is limited to the response of chemical sensors that must be located within close proximity to the CB agent. Since chemical sensors detect hazardous agents through contact, the sensor range to an airburst is the key-limiting factor in identifying a potential CB weapon attack. The associated sensor reporting latencies must be minimized to give sufficient preparation time to field commanders, who must assess if an attack is about to occur, has occurred, or if occurred, the type of agent that soldiers might be exposed to. The long-range propagation of acoustic blast waves from heavy artillery blasts, which are typical in a battlefield environment, introduces a feature for using acoustics and other sensor suite technologies for the early detection and identification of CB threats. Employing disparate sensor technologies implies that warning of a potential CB attack can be provided to the solider more rapidly and from a safer distance when compared to current conventional methods. Distinct characteristics arise within the different airburst signatures because High Explosive (HE) warheads emphasize concussive and shrapnel effects, while chemical/biological warheads are designed to disperse their contents over immense areas, therefore utilizing a slower burning, less intensive explosion to mix and distribute their contents. Highly reliable discrimination (100%) has been demonstrated at the Portable Area Warning Surveillance System

  9. Implementation of algorithms to discriminate between chemical/biological airbursts and high explosive airbursts

    NASA Astrophysics Data System (ADS)

    Hohil, Myron E.; Desai, Sachi; Morcos, Amir

    2006-09-01

    The Army is currently developing acoustic sensor systems that will provide extended range surveillance, detection, and identification for force protection and tactical security. A network of such sensors remotely deployed in conjunction with a central processing node (or gateway) will provide early warning and assessment of enemy threats, near real-time situational awareness to commanders, and may reduce potential hazards to the soldier. In contrast, the current detection of chemical/biological (CB) agents expelled into a battlefield environment is limited to the response of chemical sensors that must be located within close proximity to the CB agent. Since chemical sensors detect hazardous agents through contact, the sensor range to an airburst is the key-limiting factor in identifying a potential CB weapon attack. The associated sensor reporting latencies must be minimized to give sufficient preparation time to field commanders, who must assess if an attack is about to occur, has occurred, or if occurred, the type of agent that soldiers might be exposed to. The long-range propagation of acoustic blast waves from heavy artillery blasts, which are typical in a battlefield environment, introduces a feature for using acoustics and other sensor suite technologies for the early detection and identification of CB threats. Employing disparate sensor technologies implies that warning of a potential CB attack can be provided to the solider more rapidly and from a safer distance when compared to current conventional methods. Distinct characteristics arise within the different airburst signatures because High Explosive (HE) warheads emphasize concussive and shrapnel effects, while chemical/biological warheads are designed to disperse their contents over immense areas, therefore utilizing a slower burning, less intensive explosion to mix and distribute their contents. Highly reliable discrimination (100%) has been demonstrated at the Portable Area Warning Surveillance System

  10. High Level Waste System Impacts from Small Column Ion Exchange Implementation

    SciTech Connect

    McCabe, D. J.; Hamm, L. L.; Aleman, S. E.; Peeler, D. K.; Herman, C. C.; Edwards, T. B.

    2005-08-18

    The objective of this task is to identify potential waste streams that could be treated with the Small Column Ion Exchange (SCIX) and perform an initial assessment of the impact of doing so on the High-Level Waste (HLW) system. Design of the SCIX system has been performed as a backup technology for decontamination of High-Level Waste (HLW) at the Savannah River Site (SRS). The SCIX consists of three modules which can be placed in risers inside underground HLW storage tanks. The pump and filter module and the ion exchange module are used to filter and decontaminate the aqueous tank wastes for disposition in Saltstone. The ion exchange module contains Crystalline Silicotitanate (CST in its engineered granular form is referred to as IONSIV{reg_sign} IE-911), and is selective for removal of cesium ions. After the IE-911 is loaded with Cs-137, it is removed and the column is refilled with a fresh batch. The grinder module is used to size-reduce the cesium-loaded IE-911 to make it compatible with the sludge vitrification system in the Defense Waste Processing Facility (DWPF). If installed at the SRS, this SCIX would need to operate within the current constraints of the larger HLW storage, retrieval, treatment, and disposal system. Although the equipment has been physically designed to comply with system requirements, there is also a need to identify which waste streams could be treated, how it could be implemented in the tank farms, and when this system could be incorporated into the HLW flowsheet and planning. This document summarizes a preliminary examination of the tentative HLW retrieval plans, facility schedules, decontamination factor targets, and vitrified waste form compatibility, with recommendations for a more detailed study later. The examination was based upon four batches of salt solution from the currently planned disposition pathway to treatment in the SCIX. Because of differences in capabilities between the SRS baseline and SCIX, these four batches were

  11. [Not Available].

    PubMed

    Chevreuil, Claire; Polard, Elisabeth; Lemonnier, Eric; Guillemot, Paul; Bentué-Ferrer, Danièle

    2011-01-01

    Aripiprazole inaugurates a new generation of antipsychotics called dopamine-serotonin system stabilizers. Its mechanism of action is different as aripiprazole is a partial dopamine D2 and serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist. Therefore, aripiprazole is thought to have an antagonistic action in the mesolimbic pathway but an agonistic action in the mesocortical pathway, tending to normalize the dopaminergic transmission regardless of the type of imbalance. Clinical trials involving children and adolescents have demonstrated the efficacy of aripiprazole in bipolar disorders, schizophrenia, mood disorders associated with pervasive developmental disorders, in tics and Tourette's. The most frequent side effects are extrapyramidal symptoms and sleepiness and are dose-dependant. Nevertheless, contrary to other second-generation antipsychotics available in France, it induces little weight gain, does not modify lipid and glucidic profiles, does not increase prolactin levels, or induce QTc lengthening. The main advantage of aripiprazole is its good safety profile, with different toxicity targets to other secondgeneration antipsychotics available in France. Aripiprazole appears to be an alternative for children and adolescents who are vulnerable to these side effects and are having trouble coping with them.

  12. 76 FR 30753 - Notice of Availability of a Record of Decision (ROD) for the Proposed Honolulu High-Capacity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ...), Honolulu, HI AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Availability of Record... Administration, Honolulu Airports District Office, 300 Ala Moana Boulevard, Room 7-128, Honolulu, HI 96813. 2... Hawaii, Department of Transportation, Airports Division, 400 Rodgers Boulevard, Suite 700, Honolulu,...

  13. [Not Available].

    PubMed

    Bentué-Ferrer, Danièle; Tribut, Olivier; Verdier, Marie-Clemence

    2010-01-01

    Vigabatrin is a second generation anticonvulsant drug available in France since 1995. It is an amino acid analogue of the GABA, marketed under the racemic form [R(-)/S(+)50/50], but only the S(+)-enantiomer is active. Neither the mechanism of action of vigabatrin, an irreversible enzymatic inhibition, nor its pharmacokinetic characteristics (no binding to plasma proteins, low metabolism, no interaction with CYP), are in favour of TDM. There is no validated therapeutic range, but to the recommended dosage of 1 to 3g a day correspond plasma concentrations ranging from 0,8 to 36 mg/L (6 - 279 µmol/L). For this molecule, the level of proof of the interest of the TDM was estimated in: to be useless.

  14. [Not Available].

    PubMed

    Bouquié, Régis; Dailly, Eric; Bentué-Ferrer, Danièle

    2010-01-01

    Oxcarbazepine is an analogue of carbamazepine, used for the treatment of partial seizure with or without secondary generalization. The two forms R and S of the mono-hydroxylated derivatives (MHD) are responsible for most of the anti-convulsant activity and it is the concentrations of MHD that are relevant in therapeutic drug monitoring (TDM). Analysis of currently literature provides no well-established relationship between plasma concentration of MHD and efficiency or toxicity. Although there is not a validated therapeutic range, the residual concentrations of usually observed therapeutic MHD are situated between 12 and 30 mg/L. In certain pathological or physiological circumstances, the pharmacokinetic variability of the oxcarbazepine can be considerable, but this strong unpredictability does not nevertheless justify the TDM of the MHD. Based on the available evidence, TDM of MHD is not routinely warranted but may be possibly useful in specific situations such as pregnancy or renal insufficiency.

  15. [Not Available].

    PubMed

    Blanchard, Elodie; de Lara, Manuel Tunon

    2013-01-01

    Pholcodine is an opioid that has been widely used worldwide since 1950 for the treatment of non-productive cough in children and adults. The results of early preclinical studies but also those of recent clinical trials have shown the antitussive efficacy of pholcodine to be superior to that of codeine, of longer duration, and with an equivalent or safer toxicity profile. Also, there is no risk of addiction. Concern had been raised over a possible cross-sensitisation with neuromuscular blocking agents. While a recent assessment of the available data by the European Medicines Agency (EMA) has confirmed the favourable risk-benefit ratio of pholcodine, further studies are needed to clear this point.

  16. [Not Available].

    PubMed

    Schieveen, Pauline Gerritsen-van; Hulin, Anne; Muret, Patrice; Royer, Bernard

    2010-01-01

    Oral etoposide displays high inter- and intra-variability. Convincing relationships were observed between hematological toxicities and exposure of which total etoposide area under the curve seems the more relevant in routine practice. Linear pharmacokinetics, limited sampling strategies and reduction of variability during concentration-controlled studies argue in favor of therapeutic drug monitoring. For these reasons, such practice can be considered as recommended or potentially useful. Further studies using Bayesian approach are nevertheless needed to definitely state regarding the level of evidence therapeutic drug monitoring of oral étoposide.

  17. [Not Available].

    PubMed

    Dao, S; Diallo, S; Maiga, I; Sissoko, F; Kayantao, D

    2005-01-01

    It is about a 77 years old man admitted for a small hemoptysia and a tuberculosis history that hemoptysia had been developing in a context of 38,5 0 c fever plus some crepitate rales in the right pulmonary area. After tuberculosis has been eliminated trough the bacilloscopy procedure, investigations of aspergillus in the splits have been negative. A pulmonary x ray revealed a retractile standard opacity in right pulmonary area. Amoxicilline based treatment has been conducted for two weeks in vain. Finally the pulmonary aspergillosis diagnosis pulmonary was then accepted following highly positive aspergillary serology.

  18. Parallel implementation of high-speed, phase diverse atmospheric turbulence compensation method on a neural network-based architecture

    NASA Astrophysics Data System (ADS)

    Arrasmith, William W.; Sullivan, Sean F.

    2008-04-01

    Phase diversity imaging methods work well in removing atmospheric turbulence and some system effects from predominantly near-field imaging systems. However, phase diversity approaches can be computationally intensive and slow. We present a recently adapted, high-speed phase diversity method using a conventional, software-based neural network paradigm. This phase-diversity method has the advantage of eliminating many time consuming, computationally heavy calculations and directly estimates the optical transfer function from the entrance pupil phases or phase differences. Additionally, this method is more accurate than conventional Zernike-based, phase diversity approaches and lends itself to implementation on parallel software or hardware architectures. We use computer simulation to demonstrate how this high-speed, phase diverse imaging method can be implemented on a parallel, highspeed, neural network-based architecture-specifically the Cellular Neural Network (CNN). The CNN architecture was chosen as a representative, neural network-based processing environment because 1) the CNN can be implemented in 2-D or 3-D processing schemes, 2) it can be implemented in hardware or software, 3) recent 2-D implementations of CNN technology have shown a 3 orders of magnitude superiority in speed, area, or power over equivalent digital representations, and 4) a complete development environment exists. We also provide a short discussion on processing speed.

  19. ScalaBLAST: A Scalable Implementation of BLAST for High Performance Data-Intensive Bioinformatics Analysis

    SciTech Connect

    Oehmen, Chris S.; Nieplocha, Jarek

    2006-08-01

    Genes in an organism’s DNA (genome) have embedded in them information about proteins, which are the molecules that do most of a cell’s work. A typical bacterial genome contains on the order of 5000 genes. Mammalian genomes can contain hundreds of thousands of genes. For each genome sequenced, the challenge is to identify protein components (proteome) being actively used for a given set of conditions. Fundamentally, sequence alignment is a sequence matching problem focused at unlocking protein information embedded in the genetic code, making it possible to assemble a “tree of life” by comparing new sequences against all sequences from known organisms. But the memory footprint of sequence data is growing more rapidly than per-node core memory. Despite years of research and development, high performance sequence alignment applications either do not scale well, cannot accommodate very large databases in core, or require special hardware. We have developed a high performance sequence alignment application, ScalaBLAST, which accommodates very large databases, and which scales linearly to hundreds of processors on both distributed memory and shared memory architectures, representing a substantial improvement over the current state-of-the-art in high performance sequence alignment with scaling and portability. ScalaBLAST, relies on a collection of innovative techniques -- distributing the target database over available memory, multi-level parallelism to exploit concurrency, parallel I/O, and latency hiding through data prefetching -- to achieve high performance and scalability. This demonstrated approach of database sharing combined with effective task scheduling should have broad ranging applications to other informatics-driven sciences.

  20. Implementing a High Performance Work Place in the Distribution and Logistics Industry: Recommendations for Leadership & Team Member Development

    ERIC Educational Resources Information Center

    McCann, Laura Harding

    2012-01-01

    Leadership development and employee engagement are two elements critical to the success of organizations. In response to growth opportunities, our Distribution and Logistics company set on a course to implement High Performance Work Place to meet the leadership and employee engagement needs, and to find methods for improving work processes. This…

  1. NAGC Pre-K-Grade 12 Gifted Education Programming Standards: A Guide to Planning and Implementing High-Quality Services

    ERIC Educational Resources Information Center

    Johnsen, Susan K., Ed.

    2012-01-01

    The new Pre-K-Grade 12 Gifted Education Programming Standards should be part of every school district's repertoire of standards to ensure that the learning needs of advanced students are being met. "NAGC Pre-K-Grade 12 Gifted Education Programming Standards: A Guide to Planning and Implementing High-Quality Services" details six standards that…

  2. Implementation of a Research-Based Lab Module in a High School Chemistry Curriculum: A Study of Classroom Dynamics

    ERIC Educational Resources Information Center

    Pilarz, Matthew

    2013-01-01

    For this study, a research-based lab module was implemented in two high school chemistry classes for the purpose of examining classroom dynamics throughout the process of students completing the module. A research-based lab module developed for use in undergraduate laboratories by the Center for Authentic Science Practice in Education (CASPiE) was…

  3. Curriculum and Implementation Effects on High School Students' Mathematics Learning from Curricula Representing Subject-Specific and Integrated Content Organizations

    ERIC Educational Resources Information Center

    Grouws, Douglas A.; Tarr, James E.; Chavez, Oscar; Sears, Ruthmae; Soria, Victor M.; Taylan, Rukiye D.

    2013-01-01

    This study examined the effect of 2 types of mathematics content organization on high school students' mathematics learning while taking account of curriculum implementation and student prior achievement. Hierarchical linear modeling with 3 levels showed that students who studied from the integrated curriculum were significantly advantaged over…

  4. Implementation of a Self-Monitoring Application to Improve On-Task Behavior: A High-School Pilot Study

    ERIC Educational Resources Information Center

    Wills, Howard P.; Mason, Benjamin A.

    2014-01-01

    Technological innovations offer promise for improving intervention implementation in secondary, inclusive classrooms. A withdrawal design was employed with two high-school students in order to assess the effectiveness of a technologically delivered, self-monitoring intervention in improving on-task behavior in a science classroom. Two students…

  5. Studying the Classroom Implementation of Tasks: High-Level Mathematical Tasks Embedded in "Real-Life" Contexts

    ERIC Educational Resources Information Center

    Stylianides, Andreas J.; Stylianides, Gabriel J.

    2008-01-01

    Mathematical tasks embedded in real-life contexts have received increased attention by educators, in part due to the considerable levels of student engagement often triggered by their motivational features. Nevertheless, it is often challenging for teachers to implement high-level (i.e., cognitively demanding), real-life tasks in ways that exploit…

  6. Implementation of an Evidence-Based, High-Impact Practice: An Integrated Learning Community Model in Action

    ERIC Educational Resources Information Center

    Fuller, Karla S.; King, Claire; Moore, Randolph; Saint-Louis, Nicole; Tyner-Mullings, Alia R.

    2016-01-01

    Community colleges continue to grapple with low rates of degree completion and transfer issues, with a national three-year completion rate of 22 percent (Community College Research Center). However, through the implementation of high-impact practices, many schools and programs have found levels of success. The City University of New York's (CUNY)…

  7. The Development and Implementation of a Functional Transition Class Work Study Program at the High School Level.

    ERIC Educational Resources Information Center

    Surich, Walter L.

    A work study program was developed for five educable and trainable students in a high school transition class. A teacher's aide was trained as a job trainer at the workplace prior to program implementation; ongoing informal discussions at school with the program developer helped with problems that developed. The work study program developed…

  8. [Not Available].

    PubMed

    Jourdil, Nicole; Fonrose, Xavier; Boulieu, Roselyne; Stanke-Labesque, Françoise

    2010-01-01

    Azathioprine, 6-mercaptopurine, and 6-thioguanine are immunosuppressive drugs indicated in the prevention of graft rejection, and treatment of auto-immune disease or inflammatory bowel disease. Their anti-nucleotidic properties are also used for the treatment of acute leukaemia. Their metabolism involves thiopurine methyl transferase, which activity varies according to genetic polymorphisms. In inflammatory bowel disease patients, there is no recommended therapeutic range of intra-erythrocyte 6-thioguanine nucleotide concentration, the active metabolite. Therapeutic drug monitoring of 6-thioguanine nucleotide concentrations is however proposed in the following clinical situations: to check the observance, to try to explain therapeutic failure, to manage patients with limited thiopurine methyl transferase activity or patients treated with associated drugs that can modify thiopurine methyl transferase activity. The literature review shows that high concentrations of 6-thioguanine nucleotides and methylated metabolites are associated with an increased risk of bone marrow toxicity. In addition, high concentrations of methylated metabolite might increase the risk of hepatic toxicity. These major side-effects can be prevented by the use of pre-treatment screening for thiopurine methyl transferase activity or genotype in inflammatory bowel disease patients in order to propose an adapted dosing.

  9. Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays.

    PubMed

    Whiteaker, Jeffrey R; Halusa, Goran N; Hoofnagle, Andrew N; Sharma, Vagisha; MacLean, Brendan; Yan, Ping; Wrobel, John A; Kennedy, Jacob; Mani, D R; Zimmerman, Lisa J; Meyer, Matthew R; Mesri, Mehdi; Boja, Emily; Carr, Steven A; Chan, Daniel W; Chen, Xian; Chen, Jing; Davies, Sherri R; Ellis, Matthew J C; Fenyö, David; Hiltke, Tara; Ketchum, Karen A; Kinsinger, Chris; Kuhn, Eric; Liebler, Daniel C; Liu, Tao; Loss, Michael; MacCoss, Michael J; Qian, Wei-Jun; Rivers, Robert; Rodland, Karin D; Ruggles, Kelly V; Scott, Mitchell G; Smith, Richard D; Thomas, Stefani; Townsend, R Reid; Whiteley, Gordon; Wu, Chaochao; Zhang, Hui; Zhang, Zhen; Rodriguez, Henry; Paulovich, Amanda G

    2016-01-01

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC) of the National Cancer Institute (NCI) has launched an Assay Portal (http://assays.cancer.gov) to serve as an open-source repository of well-characterized targeted proteomic assays. The portal is designed to curate and disseminate highly characterized, targeted mass spectrometry (MS)-based assays by providing detailed assay performance characterization data, standard operating procedures, and access to reagents. Assay content is accessed via the portal through queries to find assays targeting proteins associated with specific cellular pathways, protein complexes, or specific chromosomal regions. The position of the peptide analytes for which there are available assays are mapped relative to other features of interest in the protein, such as sequence domains, isoforms, single nucleotide polymorphisms, and posttranslational modifications. The overarching goals are to enable robust quantification of all human proteins and to standardize the quantification of targeted MS-based assays to ultimately enable harmonization of results over time and across laboratories.

  10. [Not Available].

    PubMed

    Muret, Patrice; Piedoux, Sarah; Solas, Caroline; Quaranta, Sylvie

    2011-01-01

    Nevirapine, a HIV non nucleosidic reverse transcriptase inhibitor, displays an inter-individual variability in its pharmacokinetics parameters, related to its hepatic metabolism. Based on literature, is the nevirapine therapeutic drug monitoring relevant? In naïve and pre-treated HIV infected patients, the probability of achieving and maintaining an undetectable HIV viral load was significantly associated with a nevirapine plasma trough concentration (Ctrough) >4000 ng/mL. The probability of virologic failure was significantly associated with a Ctrough <3000 ng/mL. Concerning the exposure-toxicity relationship, the emergence of hepatotoxicity was more frequently associated with high Ctrough, especially in case of HCV coinfection. Non-randomized studies have reported the interest of nevirapine therapeutic drug monitoring to optimize the virologic response and, to a lesser extent, to prevent hepatotoxicity. Therefore, the level of evidence of the interest of nevirapine therapeutic drug monitoring is "recommended".

  11. [Not Available].

    PubMed

    Lefeuvre, Sandrine; Jelassi, Mohammed-Larbi; Benlmouden, Amine; Berge, Maud; Le Guellec, Chantal; Billaud, Eliane M

    2011-01-01

    Posaconazole, systemic antifungal marketed in France since 2006, is indicated as second line in curative treatment of invasive fungal infections (IFI) (aspergillosis. . . ) and prophylaxis of IFI in patients receiving chemotherapy or hematopoietic stem cell transplantation. The analysis of the literature indicates a concentration-efficacy relationship, but to date, no study has been able to show a concentration-toxicity correlation due to its favourable safety profile and the difficulty to obtain high concentrations. In curative, maintenance of trough plasma concentrations between 0.5 and 1.5 mg/L seems to be associate with an efficacy. In prophylaxis, a threshold of 0.5 mg/L corresponds to a minimal exposure. However this target is not yet well defined. Saturation of absorption above the 800 mg oral dose limits the adjustment of concentrations. As such, the Therapeutic Drug Monitoring of posaconazole can be recommended.

  12. [Not Available].

    PubMed

    Barrail-Tran, Aurélie; Taburet, Anne-Marie; Poirier, Jean-Marie

    2011-01-01

    The HIV protease inhibitor indinavir presents a wide inter-individual variability related to an intense hepatic metabolism. Published studies were analyzed to establish whether there is evidence that therapeutic drug monitoring of indinavir could improve patient care. It was reported that indinavir virological efficacy in HIV-infected patients with wild-type virus was significantly associated with trough concentrations >100-150ng/mL. Concerning the exposure-toxicity relationship, the risk of occurrence of nephrotoxicity was more frequently associated with trough concentrations >500-1 000ng/mL. Studies with concentration-controlled indinavir therapy suggest that therapeutic drug monitoring allows to achieve safe and effective concentrations, therefore, the level of evidence of the interest of indinavir therapeutic drug monitoring is highly recommended when indinavir is not associated with ritonavir and recommended when ritonavir is combined with ritonavir.

  13. 78 FR 72753 - Notice of Funds Availability for Grants for Transportation of Veterans in Highly Rural Areas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ..., 2013, 4 p.m. eastern standard time. The NOFA includes eligibility and scoring criteria for grants to assist veterans in highly rural areas through innovative transportation services to travel to VA and non... provision of VA medical care. To allow applicants more time to complete the application process, VA...

  14. [Not Available].

    PubMed

    Bentué-Ferrer, Danièle; Tribut, Olivier; Verdier, Marie-Clémence

    2010-01-01

    Valproic acid is an anticonvulsant drug available in France since 1967. It is a broad spectrum molecule indicated in various forms of epilepsy of the adult and the child, but it is also prescribed in the treatment of different other pathologies of nervous system. The divalproate sodium is indicated in the treatment of bipolar disorders. The valproic acid is marketed under various pharmaceutical forms, with different corresponding tmax values. But, whatever the administered preparation, the circulating active molecule is the ion valproate. Elimination half-life is from 11 to 20 h. Metabolization of valproate is important and represents its main route of elimination. Valpromide is comparable to a prodrug which metabolizes in valproate. The inter and intraindividual variability of the plasma concentrations are important. Several studies show a concentration-effect relationship, but two interventional trials ended in the lack of interest of the Therapeutic Drug Monitoring (TDM), although it is of current practice. However, numerous drug interactions may modify the plasma concentrations of valproate. The therapeutic range is from 50 to 100 mg/L (346 - 693 μmol/L). The level of proof of the interest of the TDM for this molecule was estimated in: recommended.

  15. Systems engineering management and implementation plan for Project W-464, immobilized high-level waste storage

    SciTech Connect

    Wecks, M.D.

    1998-04-15

    The Systems Engineering Management and Implementation Plan (SEMIP) for TWRS Project W-46 describes the project implementation of the Tank Waste Remediation System Systems Engineering Management Plan. (TWRS SEMP), Rev. 1. The SEMIP outlines systems engineering (SE) products and processes to be used by the project for technical baseline development. A formal graded approach is used to determine the products necessary for requirements, design, and operational baseline completion. SE management processes are defined, and roles and responsibilities for management processes and major technical baseline elements are documented.

  16. The ESA FELYX High Resolution Diagnostic Data Set System Design and Implementation

    NASA Astrophysics Data System (ADS)

    Taberner, M.; Shutler, J.; Walker, P.; Poulter, D.; Piolle, J.-F.; Donlon, C.; Guidetti, V.

    2013-10-01

    Felyx is currently under development and is the latest evolution of a generalised High Resolution Diagnostic Data Set system funded by ESA. It draws on previous prototype developments and experience in the GHRSST, Medspiration, GlobColour and GlobWave projects. In this paper, we outline the design and implementation of the system, and illustrate using the Ocean Colour demonstration activities. Felyx is fundamentally a tool to facilitate the analysis of EO data: it is being developed by IFREMER, PML and Pelamis. It will be free software written in python and javascript. The aim is to provide Earth Observation data producers and users with an opensource, flexible and reusable tool to allow the quality and performance of data streams from satellite, in situ and model sources to be easily monitored and studied. New to this project, is the ability to establish and incorporate multi-sensor match-up database capabilities. The systems will be deployable anywhere and even include interaction mechanisms between the deployed instances. The primary concept of Felyx is to work as an extraction tool. It allows for the extraction of subsets of source data over predefined target areas(which can be static or moving). These data subsets, and associated metrics, can then be accessed by users or client applications either as raw files or through automatic alerts. These data can then be used to generate periodic reports or be used for statistical analysis and visualisation through a flexible web interface. Felyx can be used for subsetting, the generation of statistics, the generation of reports or warnings/alerts, and in-depth analyses, to name a few. There are many potential applications but important uses foreseen are: * monitoring and assessing the quality of Earth observations (e.g. satellite products and time series) through statistical analysis and/or comparison with other data sources * assessing and inter-comparing geophysical inversion algorithms * observing a given phenomenon

  17. [Not Available].

    PubMed

    Fakhoury, May; Jacqz-Aigrain, Evelyne; de Beaumais, Tiphaine; Médard, Yves

    2010-01-01

    6-mercaptopurine, a key drug for the treatment of acute lymphoblastic leukaemia in children, is a prodrug metabolized into 6-thioguanine (6-TGN) which are the active compounds and into methylated metabolites, primary by thiopurine S-methyltransferase enzyme (TPMT). This enzyme displays important inter subject variability linked to a genetic polymorphism: when treated with standard doses of thiopurine, TPMT-deficient and heterozygous patients are at great risk for developing severe and potentially life-threatening toxicity (hematopoietic, hepatic, mucositis. . . ) but show a better survival rate while patients with high TPMT activity (wild type) present lower peripheral red blood cells 6-TGN concentrations and a higher risk of leukemia relapse. Genotyping remains crucial before 6-MP administration at diagnosis to identify patients with homozygous mutant TPMT genotype and therefore prevent severe and life-threatening toxicity, and to individualize therapy according to TMPT genotype. Follow-up of ALL treatment should preferentially be based on repeated determinations of intracellular active metabolites (6-thioguanine nucleotides) and methylated metabolites in addition to haematological surveillance.

  18. [Not Available].

    PubMed

    Muret, Patrice; Solas, Caroline

    2011-01-01

    The human immunodeficiency virus (HIV) protease inhibitor saquinavir displays a large inter-individual variability in its pharmacokinetic parameters, related to a low absorption rate and an important hepatic metabolism. Based on literature, is the saquinavir therapeutic drug monitoring relevant? In naïve HIV-infected patients, the probability of achieving an undetectable HIV viral load at W48 was significantly associated with a saquinavir plasma trough concentration > 100 ng/mL. Two studies in HIV-infected pre-treated patients reported that the genotypic inhibitory quotient was a predictive factor of virologic response with a threshold value around 40 ng/mL/mutation. Concerning the exposure-toxicity relationship, the risk of occurrence of grade 3-4 abdominal pains was more frequently associated with high concentrations of saquinavir, but without threshold value determination. Several studies, one of which was randomized, have reported the interest of saquinavir therapeutic drug monitoring to optimize the virologic response. Therefore, the level of evidence of the interest of saquinavir therapeutic drug monitoring is "recommended".

  19. [Not Available].

    PubMed

    Alm, Johan; Goksör, Emma

    2016-04-04

    Asthma, eczema, food allergy and allergic rhinitis are common and the cause is still largely unknown, but it is the subject of extensive research. The research results are inconclusive, probably due to individual differences in vulnerability to different exposures and to a highly multifactorial origin. Several environmental factors have been identified as risk factors or as having a potentially protective effect. Smoking during pregnancy or childhood increases the risk of obstructive symptoms and asthma. Breastfeeding reduces the risk of infectious diseases and thereby also the risk of early obstructive symptoms. Even if mothers avoid certain foods during pregnancy or breastfeeding, this does not reduce the risk of allergic disease in the child. The child should be introduced to foods between four and six months of age, without avoiding or delaying any particular food. Vaccinations do not affect the risk of allergic disease. The risk of allergic disease is not increased by exposure to furry animals in the home, if the child is healthy. However, children who are already allergic should at least avoid the animals to which they are allergic.

  20. [Not Available].

    PubMed

    Rodrigo, Isabel

    2008-01-01

    Diagnostic tests are a very important element in ensuring the quality of health care provided as they make, essential on occasions, a contribution to the improvement of diagnostic accuracy, and with this, therapeutic decisions. Technological development, the increased possibilities of diagnostic tests, and the growing demand for those by society means that equipment, and therefore, the number of studies carried out has grown considerably. This increased use of high technology diagnostic tests in the last few years has generated an imbalance between their supply and demand. Several studies have also pointed to the inadequate use of the most sophisticated diagnostic tests. Using a review of the scientific and grey literature, a search was made for detailed information on the variability in the provision and the requests made as regards magnetic resonance imaging (MRI) and computed axial tomography (CAT), as well as real and recommended waiting times. Strategies developed by different organisations to try to manage demand were also searched for: tools for the clinical prioritisation of patients, tools to improve the indication for use, and for assessing the appropriate use of these tests. To correct the imbalance created by the supply and demand, it seems that different strategies need to be developed and applied to influence both binomials of the equation. The strategies applied should take into account methods that have shown to be more effective in changing clinical practice, as well as those elements associated with the health context in which they have been developed.

  1. Implementing Response to Intervention: Challenges of Diversity and System Change in a High Stakes Environment

    ERIC Educational Resources Information Center

    Cavendish, Wendy; Harry, Beth; Menda, Anne Maria; Espinosa, Anabel; Mahotiere, Margarette

    2016-01-01

    Background: The Response to Intervention (RTI) approach involves the use of a dynamic model built around the systematic documentation of students' response to research-based instructional interventions. Although there has been widespread implementation of RTI models for early intervention and in some cases, as a means to identify students with…

  2. Increased Learning Time under Stimulus-Funded School Improvement Grants: High Hopes, Varied Implementation

    ERIC Educational Resources Information Center

    McMurrer, Jennifer

    2012-01-01

    Research has long suggested that significantly increasing quality time in school for teaching and learning can have a positive impact on student achievement. Recognizing this connection, federal guidance requires low-performing schools to increase student learning time if they are implementing two popular reform models using school improvement…

  3. Implementation of a School Environment Intervention to Increase Physical Activity in High School Girls

    ERIC Educational Resources Information Center

    Ward, D. S.; Saunders, R.; Felton, G. M.; Williams, E.; Epping, J. N.; Pate, R. R.

    2006-01-01

    Physical activity levels begin to decline in childhood and continue falling throughout adolescence, with girls being at greatest risk for inactivity. Schools are ideal settings for helping girls develop and maintain a physically active lifestyle. This paper describes the design and implementation of "Lifestyle Education for Activity Program", or…

  4. Systemic Impediments to the Implementation of Project Based Learning in Middle and High School Settings

    ERIC Educational Resources Information Center

    Baer, Lisa

    2014-01-01

    This study examines the potential structural impediments to the reform movement of Project Based Learning (PBL) that are presented to teachers by the inherent nature of the school system, as well as the ways in which teachers address these systemic barriers when attempting to implement PBL in their classrooms. Much of the current research that is…

  5. Implementing High School JROTC [Junior Reserve Officers Training Corps] Career Academies.

    ERIC Educational Resources Information Center

    Hanser, Lawrence M.; Robyn, Abby E.

    In 1992, the U.S. Department of Defense and U.S. Department of Education jointly developed the Junior Reserve Officers Training Corps (JROTC) Career Academy model, which provides a framework for implementation of an innovative vocational education program designed to keep dropout-prone students in school. The program, which combines military…

  6. Undergraduate Laboratory Module for Implementing ELISA on the High Performance Microfluidic Platform

    ERIC Educational Resources Information Center

    Giri, Basant; Peesara, Ravichander R.; Yanagisawa, Naoki; Dutta, Debashis

    2015-01-01

    Implementing enzyme-linked immunosorbent assays (ELISA) in microchannels offers several advantages over its traditional microtiter plate-based format, including a reduced sample volume requirement, shorter incubation period, and greater sensitivity. Moreover, microfluidic ELISA platforms are inexpensive to fabricate and allow integration of…

  7. With the Design in Mind: "High School Reform Model Features That Matter in Implementation." Conference Paper

    ERIC Educational Resources Information Center

    Shiffman, Catherine Dunn

    2015-01-01

    This paper proposes a framework for analyzing program design features that seem to matter in implementation. The framework is based on findings from a study conducted by the Consortium for Policy Research in Education (CPRE) between 2004 and 2007 that explored how reform ideas and practices created by five external provider organizations were…

  8. Do High Schools Implementing SWPBIS Have Lower Rates of Illegal Drug and Alcohol Use?

    ERIC Educational Resources Information Center

    Bastable, Eoin; Kittelman, Angus; McIntosh, Kent; Hoselton, Rob

    2015-01-01

    School-wide positive behavioral interventions and supports (SWPBIS) is a systems-level framework for improving social and academic outcomes for students in schools through the use of integrated evidence-based practices. Although the effects of SWPBIS are well-documented in elementary schools, there is increasing interest in implementing SWPBIS in…

  9. Case Study: Parent-Implemented Prelinguistic Milieu Teaching with a High Risk Dyad

    ERIC Educational Resources Information Center

    McCathren, Rebecca B.

    2010-01-01

    The purpose of this study was twofold. The first purpose was to determine if a mother with mild developmental disabilities living in poverty was able to implement Prelinguistic Milieu Teaching (PMT) strategies. The strategies included following the child's lead, arranging the environment to increase opportunities for communication, imitating the…

  10. Tee It up!: Implementing a TPSR System in a High School Golf Unit

    ERIC Educational Resources Information Center

    Busch, Nikki; Lavay, Barry

    2012-01-01

    Implementing Hellison's "Teaching Personal and Social Responsibility" (TPSR) system can help students take responsibility for their own behavior by helping students understand what it means to demonstrate appropriate behavior at various levels of responsibility. The levels range from zero through five and include: 0) irresponsibility, 1) respect,…

  11. [Not Available].

    PubMed

    Carlino, A

    1994-01-01

    Anatomical fugitive sheets are of great interest, as a typographical genre, not only for the history of printing and the history of medicine, but also, more generally, for the history of culture as a whole. They were published as folio woodcuts (more rarely engravings) in Germany, France, Italy, England and the Netherlands from the end of the XVth centkury to the mid XVIIIth century. These sheets contain a figure representing the human body (male and female) and a text describing in a concise and quite rough way the elements of the illustration. What is unusual about these sheets is that the trunk of the figures and some of the internal organs can be lifted up or peeled away, like some contemporary books for children. The figures and some internal parts are very often coloured. Judging from the number of editions (I have found 15 editions published between 1538 and 1540!), anatomical sheets met with a huge commercial success and a very wide circulation indeed. Students of the faculties of medicine and philosophy and barber-surgeons were the more obvious consumers. Students would use them as aids to memory to accompany non-illustrated medical books; barbers to grasp some basic notions of the human body, useful for the practice of phlebotomy. They could be purchased in bookshops, but they were more likely to have been sold in market places or around the University where many colporteurs displayed their cheap prints and booklets. I shall argue, however, that anatomical fugitive sheets have also been produced for and used by a non-professional public, literate but not highly educated, unable to read Latin and more used to learning from images rather than from the written word. A public that was eager to discover the inner secrets of the bodily self, the divine machine that we inhabit. From a scientific point of view anatomical fugitive sheets often reveal errors and differences compared to academic textual and iconographic material on the same subject. The discrepancy

  12. [Not Available].

    PubMed

    Spivak, M

    1987-01-01

    Some ideas, whether right or wrong, seem never to die, whatever might be the general evolution of knowledge, of science, or simply of good common sense. This is exactly the case with physical education or sports. For centuries, and especially since the middle of the nineteenth century, its advocates have fought for recognition of its all-round virtues, taken as a concept. But to attain a high level of recognition, not only in society but in official government circles, certain conditions were necessary. Education as a whole, around the middle of the nineteenth century, had to be strict and similar to military drill to be considered efficient, although the French middle classes and bourgeoisie had very little taste for the military. Although they admired physical prowess they had a horror of regimentation. But later on, when the Prussians so easily defeated Austria, feelings of doubt in French superiority began to spread, and a handful of theoreticians of physical exercise tried to show that to combat the so-called degeneration of the race, it was essential to impose a system of education in which physical exercise, coupled with military drill, still had an important place. As scientific arguments they referred to the theories of evolution and its then accepted principle, according to Lamarck, or the transmission of acquired properties and character. Darwin was still unknown in France at that time. These zealous advocates succeeded in convincing the Minister of Public Education, Victor Duruy, to include gymnastics in the normal course of studies in all schools, and by 1869 one can say that a craze for all types of physical exercise and sport had spread into many levels of society. That was the start of a never-ending movement which has passed through various stages of evolution corresponding to the changes in society itself. It has therefore changed its methods, its ways, its forms, but the overall principle remains the same, in spite of the improved understanding

  13. Effects of school-wide positive behavioral interventions and supports and fidelity of implementation on problem behavior in high schools.

    PubMed

    Flannery, K B; Fenning, P; Kato, M McGrath; McIntosh, K

    2014-06-01

    High school is an important time in the educational career of students. It is also a time when adolescents face many behavioral, academic, and social-emotional challenges. Current statistics about the behavioral, academic, and social-emotional challenges faced by adolescents, and the impact on society through incarceration and dropout, have prompted high schools to direct their attention toward keeping students engaged and reducing high-risk behavioral challenges. The purpose of the study was to examine the effects of School-Wide Positive Behavioral Interventions and Supports (SW-PBIS) on the levels of individual student problem behaviors during a 3-year effectiveness trial without random assignment to condition. Participants were 36,653 students in 12 high schools. Eight schools implemented SW-PBIS, and four schools served as comparison schools. Results of a multilevel latent growth model showed statistically significant decreases in student office discipline referrals in SW-PBIS schools, with increases in comparison schools, when controlling for enrollment and percent of students receiving free or reduced price meals. In addition, as fidelity of implementation increased, office discipline referrals significantly decreased. Results are discussed in terms of effectiveness of a SW-PBIS approach in high schools and considerations to enhance fidelity of implementation.

  14. Variation in bird's originating nitrogen availability limits High Arctic tundra development over last 2000 year (Hornsund, Svalbard)

    NASA Astrophysics Data System (ADS)

    Skrzypek, Grzegorz; Wojtuń, Bronisław; Hua, Quan; Richter, Dorota; Jakubas, Dariusz; Wojczulanis-Jakubas, Katarzyna; Samecka-Cymerman, Aleksandra

    2016-04-01

    Arctic and subarctic regions play important roles in the global carbon balance. However, nitrogen (N) deficiency is a major constraint for organic carbon sequestration in the High Arctic. Hence, the identification of the relative contributions from different N-sources is critical for understanding the constraints that limit tundra growth. The stable nitrogen composition of the three main N-sources and numerous plants were analyzed in ten tundra types (including those influenced by seabirds) in the Fuglebekken catchment (Hornsund, Svalbard, 77°N 15°E). The percentage of the total tundra N-pool provided by seabirds' feces (from planktivorous colonially breeding little auks Alle alle), ranged from 0-21% in Patterned-ground tundra to 100% in Ornithocoprophilous tundra. The total N-pool utilized by tundra plants in the studied catchment originated from birds (36%), atmospheric deposition (38%), and N2-fixation (26%). The results clearly show that N-pool in the tundra is significantly supplemented by nesting seabirds. Thus, if they experienced climate change induced substantial negative environmental pressure, it would adversely influence the tundra N-budget (Skrzypek et al. 2015). The growth rates and the sediment thickness (<15cm) in different tundra types varied considerably but the tundra age was similar in the whole area, <450 cal BP. The only exception was Ornithocoprophilous bird-N rich tundra with very diverse ages ranging from 235 to 2300 cal BP and thickness up to 110 cm. The growth rates for this tundra (62 cm core, 18 AMS 14C dates) were high (1.5-3.0 mm/yr) between 1568 and 1804 AD and then substantially declined for the period between 1804 and 1929 AD (0.2 mm/yr). These findings deliver an additional argument, that the organic matter accumulation is driven not only directly by climatic conditions but also by birds' contribution to the tundra N-pool. Skrzypek G, Wojtuń B, Richter D, Jakubas D, Wojczulanis-Jakubas K, Samecka-Cymerman A, 2015

  15. Culture-Independent Metagenomic Surveillance of Commercially Available Probiotics with High-Throughput Next-Generation Sequencing

    PubMed Central

    Patro, Jennifer N.; Ramachandran, Padmini; Barnaba, Tammy; Mammel, Mark K.; Lewis, Jada L.

    2016-01-01

    ABSTRACT Millions of people consume dietary supplements either following a doctor’s recommendation or at their own discretion to improve their overall health and well-being. This is a rapidly growing trend, with an associated and expanding manufacturing industry to meet the demand for new health-related products. In this study, we examined the contents and microbial viability of several popular probiotic products on the United States market. Culture-independent methods are proving ideal for fast and efficient analysis of foodborne pathogens and their associated microbial communities but may also be relevant for analyzing probiotics containing mixed microbial constituents. These products were subjected to next-generation whole-genome sequencing and analyzed by a custom in-house-developed k-mer counting method to validate manufacturer label information. In addition, the batch variability of respective products was examined to determine if any changes in their formulations and/or the manufacturing process occurred. Overall, the products we tested adhered to the ingredient claims and lot-to-lot differences were minimal. However, there were a few discrepancies in the naming of closely related Lactobacillus and Bifidobacterium species, whereas one product contained an apparent Enterococcus contaminant in two of its three lots. With the microbial contents of the products identified, we used traditional PCR and colony counting methods to comparatively assess our results and verify the viability of the microbes in these products with regard to the labeling claims. Of all the supplements examined, only one was found to be inaccurate in viability. Our use of next-generation sequencing as an analytical tool clearly demonstrated its utility for quickly analyzing commercially available products containing multiple microbes to ensure consumer safety. IMPORTANCE The rapidly growing supplement industry operates without a formal premarket approval process. Consumers rely on

  16. Culture-Independent Metagenomic Surveillance of Commercially Available Probiotics with High-Throughput Next-Generation Sequencing.

    PubMed

    Patro, Jennifer N; Ramachandran, Padmini; Barnaba, Tammy; Mammel, Mark K; Lewis, Jada L; Elkins, Christopher A

    2016-01-01

    Millions of people consume dietary supplements either following a doctor's recommendation or at their own discretion to improve their overall health and well-being. This is a rapidly growing trend, with an associated and expanding manufacturing industry to meet the demand for new health-related products. In this study, we examined the contents and microbial viability of several popular probiotic products on the United States market. Culture-independent methods are proving ideal for fast and efficient analysis of foodborne pathogens and their associated microbial communities but may also be relevant for analyzing probiotics containing mixed microbial constituents. These products were subjected to next-generation whole-genome sequencing and analyzed by a custom in-house-developed k-mer counting method to validate manufacturer label information. In addition, the batch variability of respective products was examined to determine if any changes in their formulations and/or the manufacturing process occurred. Overall, the products we tested adhered to the ingredient claims and lot-to-lot differences were minimal. However, there were a few discrepancies in the naming of closely related Lactobacillus and Bifidobacterium species, whereas one product contained an apparent Enterococcus contaminant in two of its three lots. With the microbial contents of the products identified, we used traditional PCR and colony counting methods to comparatively assess our results and verify the viability of the microbes in these products with regard to the labeling claims. Of all the supplements examined, only one was found to be inaccurate in viability. Our use of next-generation sequencing as an analytical tool clearly demonstrated its utility for quickly analyzing commercially available products containing multiple microbes to ensure consumer safety. IMPORTANCE The rapidly growing supplement industry operates without a formal premarket approval process. Consumers rely on product labels to

  17. Detection of highly toxic elements (lead and chromium) in commercially available eyeliner (kohl) using laser induced break down spectroscopy

    NASA Astrophysics Data System (ADS)

    Gondal, M. A.; Dastageer, M. A.; Al-Adel, F. F.; Naqvi, A. A.; Habibullah, Y. B.

    2015-12-01

    A sensitive laser induced breakdown spectroscopic system was developed and optimized for using it as a sensor for the detection of trace levels of lead and chromium present in the cosmetic eyeliner (kohl) of different price ranges (brands) available in the local market. Kohl is widely used in developing countries for babies as well adults for beautification as well eyes protection. The atomic transition lines at 405.7 nm and 425.4 nm were used as the marker lines for the detection of lead and chromium respectively. The detection system was optimized by finding the appropriate gate delay between the laser excitation and the data acquisition system and also by achieving optically thin plasma near the target by establishing the local thermodynamic equilibrium condition. The detection system was calibrated for these two hazardous elements and the kohl samples under investigation showed 8-15 ppm by mass of lead and 4-9 ppm by mass of Chromium, which are higher than the safe permissible levels of these elements. The limits of detection of the LIBS system for lead and chromium were found to be 1 and 2 ppm respectively.

  18. The National Cross-Site Evaluation of High-Risk Youth Programs: Findings on Designing and Implementing Effective Prevention Programs for Youth at High Risk. Monograph Series.

    ERIC Educational Resources Information Center

    Hermann, Jack; Sambrano, Soledad; Springer, J. Fred; Nister, Mary; Sale, Elizabeth; Brounstein, Paul J.; Cordray, David; Shadish, Will; Kasim, Rafa; Pan, Wei

    This document summarizes findings from the Center for Substance Abuse Prevention's National Cross-Site Evaluation of High-Risk Youth Programs, which identified characteristics associated with strong substance abuse prevention outcomes in 48 prevention programs. It provides concrete guidance regarding what elements of design and implementation are…

  19. The Causality Study of External Environment Analysis (EEA), Internal Environment Analysis (IEA), Strategy Implementation on Study Program Performance at Vocational High School (VHS) in Nias Archipelago, Indonesia

    ERIC Educational Resources Information Center

    Waruwu, Binahati; Sitompul, Harun; Manullang, Belferik

    2016-01-01

    The purposes of this study are to find out the significant effect of: (1) EEA on strategy implementation, (2) IEA on strategy implementation, (3) EEA on study program performance, (4) IEA on study program performance, and (5) strategy implementation on study program performance of Vocational High School (VHS) in Nias Archipelago. The population of…

  20. Sector and Sphere: the design and implementation of a high-performance data cloud.

    PubMed

    Gu, Yunhong; Grossman, Robert L

    2009-06-28

    Cloud computing has demonstrated that processing very large datasets over commodity clusters can be done simply, given the right programming model and infrastructure. In this paper, we describe the design and implementation of the Sector storage cloud and the Sphere compute cloud. By contrast with the existing storage and compute clouds, Sector can manage data not only within a data centre, but also across geographically distributed data centres. Similarly, the Sphere compute cloud supports user-defined functions (UDFs) over data both within and across data centres. As a special case, MapReduce-style programming can be implemented in Sphere by using a Map UDF followed by a Reduce UDF. We describe some experimental studies comparing Sector/Sphere and Hadoop using the Terasort benchmark. In these studies, Sector is approximately twice as fast as Hadoop. Sector/Sphere is open source.

  1. Sector and Sphere: the design and implementation of a high-performance data cloud

    PubMed Central

    Gu, Yunhong; Grossman, Robert L.

    2009-01-01

    Cloud computing has demonstrated that processing very large datasets over commodity clusters can be done simply, given the right programming model and infrastructure. In this paper, we describe the design and implementation of the Sector storage cloud and the Sphere compute cloud. By contrast with the existing storage and compute clouds, Sector can manage data not only within a data centre, but also across geographically distributed data centres. Similarly, the Sphere compute cloud supports user-defined functions (UDFs) over data both within and across data centres. As a special case, MapReduce-style programming can be implemented in Sphere by using a Map UDF followed by a Reduce UDF. We describe some experimental studies comparing Sector/Sphere and Hadoop using the Terasort benchmark. In these studies, Sector is approximately twice as fast as Hadoop. Sector/Sphere is open source. PMID:19451100

  2. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1987-01-01

    Performance analysis was begin on the Ada implementations. The goal is to supply the system designer with tools that will allow a rational decision to be made about whether a particular implementation can support a given application early in the design cycle. Primary activities were: analysis of the original approach to recovery in distributed Ada programs using the Advanced Transport Operating System (ATOPS) example; review and assessment of the original approach which was found to be capable of improvement; preparation and presentation of a paper at the 1987 Washington DC Ada Symposium; development of a refined approach to recovery that is presently being applied to the ATOPS example; and design and development of a performance assessment scheme for Ada programs based on a flexible user-driven benchmarking system.

  3. Implementation Challenges for Sintered Silicon Carbide Fiber Bonded Ceramic Materials for High Temperature Applications

    NASA Technical Reports Server (NTRS)

    Singh, M.

    2011-01-01

    During the last decades, a number of fiber reinforced ceramic composites have been developed and tested for various aerospace and ground based applications. However, a number of challenges still remain slowing the wide scale implementation of these materials. In addition to continuous fiber reinforced composites, other innovative materials have been developed including the fibrous monoliths and sintered fiber bonded ceramics. The sintered silicon carbide fiber bonded ceramics have been fabricated by the hot pressing and sintering of silicon carbide fibers. However, in this system reliable property database as well as various issues related to thermomechanical performance, integration, and fabrication of large and complex shape components has yet to be addressed. In this presentation, thermomechanical properties of sintered silicon carbide fiber bonded ceramics (as fabricated and joined) will be presented. In addition, critical need for manufacturing and integration technologies in successful implementation of these materials will be discussed.

  4. Computer-implemented system and method for automated and highly accurate plaque analysis, reporting, and visualization

    NASA Technical Reports Server (NTRS)

    Kemp, James Herbert (Inventor); Talukder, Ashit (Inventor); Lambert, James (Inventor); Lam, Raymond (Inventor)

    2008-01-01

    A computer-implemented system and method of intra-oral analysis for measuring plaque removal is disclosed. The system includes hardware for real-time image acquisition and software to store the acquired images on a patient-by-patient basis. The system implements algorithms to segment teeth of interest from surrounding gum, and uses a real-time image-based morphing procedure to automatically overlay a grid onto each segmented tooth. Pattern recognition methods are used to classify plaque from surrounding gum and enamel, while ignoring glare effects due to the reflection of camera light and ambient light from enamel regions. The system integrates these components into a single software suite with an easy-to-use graphical user interface (GUI) that allows users to do an end-to-end run of a patient record, including tooth segmentation of all teeth, grid morphing of each segmented tooth, and plaque classification of each tooth image.

  5. FPGA implementation of high-frequency multiple PWM for variable voltage variable frequency controller

    NASA Astrophysics Data System (ADS)

    Boumaaraf, Abdelâali; Mohamadi, Tayeb; Gourmat, Laïd

    2016-07-01

    In this paper, we present the FPGA implementation of the multiple pulse width modulation (MPWM) signal generation with repetition of data segments, applied to the variable frequency variable voltage systems and specially at to the photovoltaic water pumping system, in order to generate a signal command very easily between 10hz to 60 hz with a small frequency and reduce the cost of the control system.

  6. A Highly Parallel Implementation of K-Means for Multithreaded Architecture

    SciTech Connect

    Mackey, Patrick S.; Feo, John T.; Wong, Pak C.; Chen, Yousu

    2011-04-06

    We present a parallel implementation of the popular k-means clustering algorithm for massively multithreaded computer systems, as well as a parallelized version of the KKZ seed selection algorithm. We demonstrate that as system size increases, sequential seed selection can become a bottleneck. We also present an early attempt at parallelizing k-means that highlights critical performance issues when programming massively multithreaded systems. For our case studies, we used data collected from electric power simulations and run on the Cray XMT.

  7. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.; Gregory, S. T.; Urquhart, J. I. A.

    1984-01-01

    The use and implementation of Ada (a trade mark of the US Dept. of Defense) in distributed environments in which the hardware are assumed to be unreliable were investigated. The possibility that a distributed system is programmed entirely in Ada so that the individual tasks of the system are unconcerned with which processors they are executing on and failures occurring in the underlying hardware were examined.

  8. Using the CPTAC Assay Portal to identify and implement highly characterized targeted proteomics assays

    SciTech Connect

    Whiteaker, Jeffrey R.; Halusa, Goran; Hoofnagle, Andrew N.; Sharma, Vagisha; MacLean, Brendan; Yan, Ping; Wrobel, John; Kennedy, Jacob; Mani, DR; Zimmerman, Lisa J.; Meyer, Matthew R.; Mesri, Mehdi; Boja, Emily; Carr, Steven A.; Chan, Daniel W.; Chen, Xian; Chen, Jing; Davies, Sherri; Ellis, Matthew; Fenyo, David; Hiltket, Tara; Ketchum, Karen; Kinsinger, Christopher; Kuhn, Eric; Liebler, Daniel; Liu, Tao; Loss, Michael; MacCoss, Michael; Qian, Weijun; Rivers, Robert; Rodland, Karin D.; Ruggles, Kelly; Scott, Mitchell; Smith, Richard D.; Thomas, Stefani N.; Townsend, Reid; Whiteley, Gordon; Wu, Chaochao; Zhang, Hui; Zhang, Zhen; Rodriguez, Henry; Paulovich, Amanda G.

    2016-02-12

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC) of the National Cancer Institute (NCI) has launched an Assay Portal (http://assays.cancer.gov) to serve as an open-source repository of well-characterized targeted proteomic assays. The portal is designed to curate and disseminate highly characterized, targeted mass spectrometry (MS)-based assays by providing detailed assay performance characterization data, standard operating procedures, and access to reagents. Assay content is accessed via the portal through queries to find assays targeting proteins associated with specific cellular pathways, protein complexes, or specific chromosomal regions. The position of the peptide analytes for which there are available assays are mapped relative to other features of interest in the protein, such as sequence domains, isoforms, single nucleotide polymorphisms, and post-translational modifications. The overarching goals are to enable robust quantification of all human proteins and to standardize the quantification of targeted MS-based assays to ultimately enable harmonization of results over time and across laboratories.

  9. ASIC Implementation of Highly Reliable IR-UWB Transceiver for Industrial Automation

    NASA Astrophysics Data System (ADS)

    Olonbayar, Sonom; Fischer, Gunter; Kreiser, Dan; Martynenko, Denys; Klymenko, Oleksiy; Kraemer, Rolf; Grass, Eckhard

    2016-07-01

    An in-depth treatment of impulse an radio ultra-wideband (IR-UWB) wireless system is provided reviewing theoretical background, proceeding with detailed implementation procedure, and finally giving simulation and test results. This is the first research and prototyping work to be published in the field of IR-UWB that operates in the 6-8 GHz band. The aim of this work is to implement an IR-UWB wireless system for industrial automation that is robust and reliable. To achieve this, an analogue bandwidth of 250 MHz and digital baseband processing at the clock frequency 499.2 MHz were realized in a 250 nm BiCMOS process, integrating the complete system into a single chip. Simulation and measurement results confirm that the implemented IR-UWB transceiver is operational across four frequency channels in the band 6-8 GHz each supporting three data rates 850 kb/s, 6.81 Mb/s and 27.24 Mb/s.

  10. Matched interface and boundary (MIB) for the implementation of boundary conditions in high-order central finite differences

    PubMed Central

    Zhao, Shan; Wei, G. W.

    2010-01-01

    SUMMARY High-order central finite difference schemes encounter great difficulties in implementing complex boundary conditions. This paper introduces the matched interface and boundary (MIB) method as a novel boundary scheme to treat various general boundary conditions in arbitrarily high-order central finite difference schemes. To attain arbitrarily high order, the MIB method accurately extends the solution beyond the boundary by repeatedly enforcing only the original set of boundary conditions. The proposed approach is extensively validated via boundary value problems, initial-boundary value problems, eigenvalue problems, and high-order differential equations. Successful implementations are given to not only Dirichlet, Neumann, and Robin boundary conditions, but also more general ones, such as multiple boundary conditions in high-order differential equations and time-dependent boundary conditions in evolution equations. Detailed stability analysis of the MIB method is carried out. The MIB method is shown to be able to deliver high-order accuracy, while maintaining the same or similar stability conditions of the standard high-order central difference approximations. The application of the proposed MIB method to the boundary treatment of other non-standard high-order methods is also considered. PMID:20485574

  11. Availability of High Quality TRMM Ground Validation Data from Kwajalein, RMI: A Practical Application of the Relative Calibration Adjustment Technique

    NASA Technical Reports Server (NTRS)

    Marks, David A.; Wolff, David B.; Silberstein, David S.; Tokay, Ali; Pippitt, Jason L.; Wang, Jianxin

    2008-01-01

    Since the Tropical Rainfall Measuring Mission (TRMM) satellite launch in November 1997, the TRMM Satellite Validation Office (TSVO) at NASA Goddard Space Flight Center (GSFC) has been performing quality control and estimating rainfall from the KPOL S-band radar at Kwajalein, Republic of the Marshall Islands. Over this period, KPOL has incurred many episodes of calibration and antenna pointing angle uncertainty. To address these issues, the TSVO has applied the Relative Calibration Adjustment (RCA) technique to eight years of KPOL radar data to produce Ground Validation (GV) Version 7 products. This application has significantly improved stability in KPOL reflectivity distributions needed for Probability Matching Method (PMM) rain rate estimation and for comparisons to the TRMM Precipitation Radar (PR). In years with significant calibration and angle corrections, the statistical improvement in PMM distributions is dramatic. The intent of this paper is to show improved stability in corrected KPOL reflectivity distributions by using the PR as a stable reference. Inter-month fluctuations in mean reflectivity differences between the PR and corrected KPOL are on the order of 1-2 dB, and inter-year mean reflectivity differences fluctuate by approximately 1 dB. This represents a marked improvement in stability with confidence comparable to the established calibration and uncertainty boundaries of the PR. The practical application of the RCA method has salvaged eight years of radar data that would have otherwise been unusable, and has made possible a high-quality database of tropical ocean-based reflectivity measurements and precipitation estimates for the research community.

  12. A One Chip Hardened Solution for High Speed SpaceWire System Implementations. Session: Components

    NASA Technical Reports Server (NTRS)

    Marshall, Joseph R.; Berger, Richard W.; Rakow, Glenn P.

    2007-01-01

    An Application Specific Integrated Circuit (ASIC) that implements the SpaceWire protocol has been developed in a radiation hardened 0.25 micron CMOS technology. This effort began in March 2003 as a joint development between the NASA Goddard Space Flight Center (GSFC) and BAE Systems. The BAE Systems SpaceWire ASIC is comprised entirely of reusable core elements, many of which are already flight-proven. It incorporates a router with 4 SpaceWire ports and two local ports, dual PC1 bus interfaces, a microcontroller, 32KB of internal memory, and a memory controller for additional external memory use. The SpaceWire cores are also reused in other ASICs under development. The SpaceWire ASIC is planned for use on the Geostationary Operational Environmental Satellites (GOES)-R, the Lunar Reconnaissance Orbiter (LRO) and other missions. Engineering and flight parts have been delivered to programs and users. This paper reviews the SpaceWire protocol and those elements of it that have been built into the current and next SpaceWire reusable cores and features within the core that go beyond the current standard and can be enabled or disabled by the user. The adaptation of SpaceWire to BAE Systems' On Chip Bus (OCB) for compatibility with the other reusable cores will be reviewed and highlighted. Optional configurations within user systems and test boards will be shown. The physical implementation of the design will be described and test results from the hardware will be discussed. Application of this ASIC and other ASICs containing the SpaceWire cores and embedded microcontroller to Plug and Play and reconfigurable implementations will be described. Finally, the BAE Systems roadmap for SpaceWire developments will be updated, including some products already in design as well as longer term plans.

  13. Design and Implementation of High Frequency Ultrasound Pulsed-Wave Doppler Using FPGA

    PubMed Central

    Hu, Chang-hong; Zhou, Qifa; Shung, K. Kirk

    2009-01-01

    The development of a field-programmable gate array (FPGA)-based pulsed-wave Doppler processing approach in pure digital domain is reported in this paper. After the ultrasound signals are digitized, directional Doppler frequency shifts are obtained with a digital-down converter followed by a low-pass filter. A Doppler spectrum is then calculated using the complex fast Fourier transform core inside the FPGA. In this approach, a pulsed-wave Doppler implementation core with reconfigurable and real-time processing capability is achieved. PMID:18986909

  14. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1984-01-01

    The use and implementation of Ada in distributed environments in which reliability is the primary concern is investigated. Emphasis is placed on the possibility that a distributed system may be programmed entirely in ADA so that the individual tasks of the system are unconcerned with which processors they are executing on, and that failures may occur in the software or underlying hardware. The primary activities are: (1) Continued development and testing of our fault-tolerant Ada testbed; (2) consideration of desirable language changes to allow Ada to provide useful semantics for failure; (3) analysis of the inadequacies of existing software fault tolerance strategies.

  15. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1987-01-01

    A preliminary analysis of the Ada implementation of the Advanced Transport Operating System (ATOPS), an experimental computer control system developed at NASA Langley for a modified Boeing 737 aircraft, is presented. The criteria that was determined for the evaluation of this approach is described. A preliminary version of the requirements for the ATOPS is contained. This requirements specification is not a formal document, but rather a description of certain aspects of the ATOPS system at a level of detail that best suits the needs of the research. The survey of backward error recovery techniques is also presented.

  16. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1986-01-01

    The use and implementation of Ada in distributed environments in which reliability is the primary concern were investigted. A distributed system, programmed entirely in Ada, was studied to assess the use of individual tasks without concern for the processor used. Continued development and testing of the fault tolerant Ada testbed; development of suggested changes to Ada to cope with the failures of interest; design of approaches to fault tolerant software in real time systems, and the integration of these ideas into Ada; and the preparation of various papers and presentations were discussed.

  17. High-level message-passing constructs for Zipcode 1.0: Design and implementation

    SciTech Connect

    Smith, S.G.; Falgout, R.D.; Still, C.H.; Skjellum, A.

    1993-10-01

    Zipcode is a message passing system that was initially designed for multicomputers and homogeneous networks of computers. This paper describes Zipcode ``invoices,`` which raise the message-passing interface of Zipcode to a higher level of abstraction. The ``gather-send`` and ``receive-scatter`` semantics enable heterogeneous communication. The higher level of abstraction also simplifies message passing and reveals more optimizations. We explain the utility of these features and give examples of the calling sequences that implement them. All of these features are seen as enablers for parallel library development and large applications.

  18. Reduced Availability of Sugar-Sweetened Beverages and Diet Soda Has a Limited Impact on Beverage Consumption Patterns in Maine High School Youth

    ERIC Educational Resources Information Center

    Whatley Blum, Janet E.; Davee, Anne-Marie; Beaudoin, Christina M.; Jenkins, Paul L.; Kaley, Lori A.; Wigand, Debra A.

    2008-01-01

    Objective: To examine change in high school students' beverage consumption patterns pre- and post-intervention of reduced availability of sugar-sweetened beverages (SSB) and diet soda in school food venues. Design: A prospective, quasi-experimental, nonrandomized study design. Setting: Public high schools. Participants: A convenience sample from…

  19. The implementation and use of ADA on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1985-01-01

    The use and implementation of Ada in distributed environments in which reliability is the primary concern is investigated. Emphasis is placed on the possibility that a distributed system may be programmed entirely in Ada so that the individual tasks of the system are unconcerned with which processors they are executing on, and that failures may occur in the software or underlying hardware. A new linguistic construct, the colloquy, is introduced which solves the problems identified in an earlier proposal, the conversation. It was shown that the colloquy is at least as powerful as recovery blocks, but it is also as powerful as all the other language facilities proposed for other situations requiring backward error recovery: recovery blocks, deadlines, generalized exception handlers, traditional conversations, s-conversations, and exchanges. The major features that distinguish the colloquy are described. Sample programs that were written, but not executed, using the colloquy show that extensive backward error recovery can be included in these programs simply and elegantly. These ideas are being implemented in an experimental Ada test bed.

  20. Real-Time Kennedy Space Center and Cape Canaveral Air Force Station High-Resolution Model Implementation and Verification

    NASA Technical Reports Server (NTRS)

    Shafer, Jaclyn A.; Watson, Leela R.

    2015-01-01

    Customer: NASA's Launch Services Program (LSP), Ground Systems Development and Operations (GSDO), and Space Launch System (SLS) programs. NASA's LSP, GSDO, SLS and other programs at Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS) use the daily and weekly weather forecasts issued by the 45th Weather Squadron (45 WS) as decision tools for their day-to-day and launch operations on the Eastern Range (ER). For example, to determine if they need to limit activities such as vehicle transport to the launch pad, protect people, structures or exposed launch vehicles given a threat of severe weather, or reschedule other critical operations. The 45 WS uses numerical weather prediction models as a guide for these weather forecasts, particularly the Air Force Weather Agency (AFWA) 1.67 kilometer Weather Research and Forecasting (WRF) model. Considering the 45 WS forecasters' and Launch Weather Officers' (LWO) extensive use of the AFWA model, the 45 WS proposed a task at the September 2013 Applied Meteorology Unit (AMU) Tasking Meeting requesting the AMU verify this model. Due to the lack of archived model data available from AFWA, verification is not yet possible. Instead, the AMU proposed to implement and verify the performance of an ER version of the AMU high-resolution WRF Environmental Modeling System (EMS) model (Watson 2013) in real-time. The tasking group agreed to this proposal; therefore the AMU implemented the WRF-EMS model on the second of two NASA AMU modeling clusters. The model was set up with a triple-nested grid configuration over KSC/CCAFS based on previous AMU work (Watson 2013). The outer domain (D01) has 12-kilometer grid spacing, the middle domain (D02) has 4-kilometer grid spacing, and the inner domain (D03) has 1.33-kilometer grid spacing. The model runs a 12-hour forecast every hour, D01 and D02 domain outputs are available once an hour and D03 is every 15 minutes during the forecast period. The AMU assessed the WRF-EMS 1

  1. High fat/carbohydrate ratio but not total energy intake induces lower striatal dopamine D2/3 receptor availability in diet-induced obesity.

    PubMed

    van de Giessen, E; la Fleur, S E; Eggels, L; de Bruin, K; van den Brink, W; Booij, J

    2013-05-01

    High-energy diets that induce obesity decrease striatal dopamine D2/3 receptor (DRD2/3) availability. It is however poorly understood which components of these diets are underlying this decrease. This study assessed the role of saturated fat intake on striatal DRD2/3 availability. Forty rats were randomized to a free-choice high-fat high-sugar diet (HFHS) or a standard chow diet for 28 days. Striatal DRD2/3 availability was measured using (123)I-IBZM storage phosphor imaging at day 29. The HFHS group was split in a HFHS-high-fat (HFHS-hf) and HFHS-low-fat (HFHS-lf) group based on the percentage energy intake from fat. Rats of both HFHS subgroups had increased energy intake, abdominal fat stores and plasma leptin levels compared with controls. DRD2/3 availability in the nucleus accumbens (NAcc) was significantly lower in HFHS-hf than in HFHS-lf rats, whereas it was similar for HFHS-lf and control rats. Furthermore, DRD2/3 availability in the NAcc was positively correlated with the percentage energy intake from sugar. Total energy intake was lower for HFHS-hf than for HFHS-lf rats. Together these results suggest that a diet with a high fat/carbohydrate ratio, but not total energy intake or the level of adiposity, is the best explanation for the decrease in striatal DRD2/3 availability observed in diet-induced obesity.

  2. 75 FR 75625 - Approval and Promulgation of Implementation Plans; North Carolina: Greensboro-Winston-Salem-High...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-06

    ...-Winston-Salem-High Point; Determination of Attaining Data for the 1997 Fine Particulate Matter Standard...: On January 4, 2010, EPA published a final rule determining that the Greensboro-Winston-Salem-High... Attaining Data. EPA has determined, as of January 4, 2010, the Greensboro-Winston-Salem-High Point,...

  3. Some Health Effects of Implementing School Nursing in a Norwegian High School: A Controlled Study

    ERIC Educational Resources Information Center

    Svebak, Sven; Jensen, Eva Naper; Gotestam, K. Gunnar

    2008-01-01

    The effects of a school nursing service on health complaints and mood were investigated in a Norwegian high school. The school nursing service was delivered to students in 1 high school, and students in a comparable high school served as the comparison group. There were 41 students in the treatment group and 63 in the comparison group. All…

  4. Cheng Cycle reporting high availability

    SciTech Connect

    Not Available

    1986-02-01

    Operating results from the Cheng Cycle cogeneration plants at San Jose State University and at Sunkist Growers in Ontario, California look very good so far, according to officials of International Power Technology (IPT). Both plants contain IPT's Cheng Cycle Series 7-Cogen system, which produces between 3 and 6 MW of electricity and up to 45,000 pounds of steam per hour. The company is developing the patented technology as an improved combined cycle system which can produce steam and electricity under widely varying load demands.

  5. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.

    1988-01-01

    The use and implementation of Ada were investigated in distributed environments in which reliability is the primary concern. In particular, the focus was on the possibility that a distributed system may be programmed entirely in Ada so that the individual tasks of the system are unconcerned with which processors are being executed, and that failures may occur in the software and underlying hardware. A secondary interest is in the performance of Ada systems and how that performance can be gauged reliably. Primary activities included: analysis of the original approach to recovery in distributed Ada programs using the Advanced Transport Operating System (ATOPS) example; review and assessment of the original approach which was found to be capable of improvement; development of a refined approach to recovery that was applied to the ATOPS example; and design and development of a performance assessment scheme for Ada programs based on a flexible user-driven benchmarking system.

  6. The implementation and use of Ada on distributed systems with high reliability requirements

    NASA Technical Reports Server (NTRS)

    Knight, J. C.; Gregory, S. T.; Urquhart, J. I. A.

    1985-01-01

    The use and implementation of Ada in distributed environments in which reliability is the primary concern were investigated. In particular, the concept that a distributed system may be programmed entirely in Ada so that the individual tasks of the system are unconcerned with which processors they are executing on, and that failures may occur in the software or underlying hardware was examined. Progress is discussed for the following areas: continued development and testing of the fault-tolerant Ada testbed; development of suggested changes to Ada so that it might more easily cope with the failure of interest; and design of new approaches to fault-tolerant software in real-time systems, and integration of these ideas into Ada.

  7. Systemic impediments to the implementation of Project Based Learning in middle and high school settings

    NASA Astrophysics Data System (ADS)

    Bouilly, Delphine

    This study examines the potential structural impediments to the reform movement of Project Based Learning (PBL) that are presented to teachers by the inherent nature of the school system, as well as the ways in which teachers address these systemic barriers when attempting to implement PBL in their classrooms. Much of the current research that is aimed at investigating the transition from traditional teacher-centered learning to student-centered PBL---whether PBL as problem based or project based learning---has focused on the transition issues at the level of individual teacher/student. Systemic barriers, on the other hand, are those features that are inherent to the structure of the system, and that pose---by their very nature---physical and/or political circumstances that are inconsistent with the student-centered and collaborative goals of PBL. It is not enough for teachers, parents, students, and administrators to be philosophically aligned with PBL, if the encompassing school system is structurally incompatible with the method. This study attempts to make the structural impediments to PBL explicit, to determine whether or not the existing school system is amenable to the successful implementation of PBL. Because the universal features of PBL coupled with the ubiquity of factory-model schools is likely to create recurring themes, it is plausible that this study may in fact be analytically generalizable to situations beyond those described by the populations and contexts in this set of purposive, multiple cases. One of the themes that emerged from this study was the role of rural poverty as an underlying cause of student apathy. More research may be needed to see whether science, as taught through PBL and in collaboration with practical arts courses, might be able to address some of the social, gendered, and educational needs of impoverished rural students and their families.

  8. Early Warning System Implementation Guide: For Use with the National High School Center's Early Warning System Tool v2.0

    ERIC Educational Resources Information Center

    Therriault, Susan Bowles; Heppen, Jessica; O'Cummings, Mindee; Fryer, Lindsay; Johnson, Amy

    2010-01-01

    This Early Warning System (EWS) Implementation Guide is a supporting document for schools and districts that are implementing the National High School Center's Early Warning System (EWS) Tool v2.0. Developed by the National High School Center at the American Institutes for Research (AIR), the guide and tool support the establishment and…

  9. A Post Secondary Prevocational Education Model: A Guide for Implementation. A Research Verified Training Program to Help the High-Risk Student Complete Post Secondary Education.

    ERIC Educational Resources Information Center

    Blattner, Bruce E.; And Others

    This guide comprises a summary of the development of and materials for use in the implementation of a research-verified model training program to help high-risk students complete postsecondary education programs. Discussed first is the original pilot project that was implemented to serve the high-risk postsecondary vocational students entering the…

  10. An Analysis of High School Math, Science, Social Studies, English, and Foreign Language Teachers' Implementation of One-to-One Computing and Their Pedagogical Practices

    ERIC Educational Resources Information Center

    Inserra, Albert; Short, Thomas

    2013-01-01

    The purpose of this study was to compare high school Math, Science, Social Studies, English, and Foreign Language teachers' implementation of teaching practices in terms of their pedagogical dimensions in a one-to-one computing environment. A survey was developed to measure high school teachers' implementation of teaching practices associated with…

  11. Implementing 15 Essential Elements for High Quality: A State and Local Policy Scan

    ERIC Educational Resources Information Center

    Barnett, W. Steven; Weisenfeld, G. G.; Brown, Kirsty; Squires, Jim; Horowitz, Michelle

    2016-01-01

    This report explores the extent to which states (and several large cities) are positioned to provide high quality preschool education on a large scale. States and cities that are already doing so or that could do so with modest improvements offer opportunities for advocacy to advance access to high quality early education as well as for rigorous…

  12. Use of Formative Research to Develop a Yoga Curriculum for High-Risk Youth: Implementation Considerations

    ERIC Educational Resources Information Center

    Miller, Shari; Herman-Stahl, Mindy; Fishbein, Diana; Lavery, Bud; Johnson, Michelle; Markovits, Lara

    2014-01-01

    The purpose of this study is to elucidate the use of formative research to adapt, develop, and pretest a mindful yoga curriculum for high-risk youth attending a nontraditional high school. The formative work was conducted in the first year of a larger project to test the efficacy of a mindful yoga program through a randomized controlled trial. The…

  13. Alternatives in Scheduling Patterns: Practitioner Implementation of Minicourse Programs in Selected Midwestern High Schools.

    ERIC Educational Resources Information Center

    Hansen, Patricia; Guenther, John

    The purposes of the document are to report on the status of social studies minicourse programs in selected midwestern high schools and to provide information to schools regarding obstacles to minicourses as alternatives to traditional programs. A 1976-77 survey of 265 midwestern high schools determined that only 60 (23%) of the schools offered…

  14. Design and Implementation of High School Reform: Perspectives from Research and Practice

    ERIC Educational Resources Information Center

    Smith, Thomas M.

    2016-01-01

    There has been a proliferation of high school reform models and interventions over the past few decades aimed at improving the nation's high schools, including increasing graduation requirements, introducing technology to classrooms, grouping ninth-grade students into their own "academies," reorienting the curriculum toward particular…

  15. Third-Year High School Mathematics Curriculum: Effects of Content Organization and Curriculum Implementation

    ERIC Educational Resources Information Center

    Chávez, Óscar; Tarr, James E.; Grouws, Douglas A.; Soria, Victor M.

    2015-01-01

    We examined the effect of curriculum organization in US high schools where students could freely choose to study mathematics from textbooks that employed one of two types of content organization, an "integrated" approach or a (traditional) "subject-specific" approach. The study involved 2,242 high school students, enrolled in…

  16. Evaluation of Academic Policy Formulation and Implementation Transmountain Early College High School, El Paso, Texas

    ERIC Educational Resources Information Center

    Heidemann, Virginia Margaret

    2010-01-01

    Transmountain Early College High School (TMECHS) opened in August 2008, created by a partnership between the El Paso Community College (EPCC) and the El Paso Independent School District (EPISD), and supported in its conceptualization, start-up, and first few years operation by grant funding and guidance from the Texas High School Project (THSP)…

  17. Effects of Implementing STEM-I Project-Based Learning Activities for Female High School Students

    ERIC Educational Resources Information Center

    Lou, Shi-Jer; Tsai, Huei-Yin; Tseng, Kuo-Hung; Shih, Ru-Chu

    2014-01-01

    This study aims to explore the application of STEM-I (STEM-Imagination) project-based learning activities and its effects on the effectiveness, processes, and characteristics of STEM integrative knowledge learning and imagination development for female high school students. A total of 72 female high school students were divided into 18 teams.…

  18. Implementing an Affordable High-Performance Computing for Teaching-Oriented Computer Science Curriculum

    ERIC Educational Resources Information Center

    Abuzaghleh, Omar; Goldschmidt, Kathleen; Elleithy, Yasser; Lee, Jeongkyu

    2013-01-01

    With the advances in computing power, high-performance computing (HPC) platforms have had an impact on not only scientific research in advanced organizations but also computer science curriculum in the educational community. For example, multicore programming and parallel systems are highly desired courses in the computer science major. However,…

  19. Implementation of large-scale landscape evolution modelling to real high-resolution DEM

    NASA Astrophysics Data System (ADS)

    Schroeder, S.; Babeyko, A. Y.

    2012-12-01

    We have developed a surface evolution model to be naturally integrated with 3D thermomechanical codes like SLIM-3D to study coupled tectonic-climate interaction. The resolution of the surface evolution model is independent of that of the underlying continuum box. The surface model follows the concept of the cellular automaton implemented on a regular Eulerian mesh. It incorporates an effective filling algorithm that guarantees flow direction in each cell, D8 search for flow directions, computation of discharges and bedrock incision. Additionally, the model implements hillslope erosion in the form of non-linear, slope-dependent diffusion. The model was designed to be employed not only to synthetic topographies but also to real Digital Elevation Models (DEM). In present work we report our experience with model implication to the 30-meter resolution ASTER GDEM of the Pamir orogen, in particular, to the segment of the Panj river. We start with calibration of the model parameters (fluvial incision and hillslope diffusion coefficients) using direct measurements of Panj incision rates and volumes of suspended sediment transport. Since the incision algorithm is independent on hillslope processes, we first adjust the incision parameters. Power-law exponents of the incision equation were evaluated from the profile curvature of the main Pamir rivers. After that, incision coefficient was adjusted to fit the observed incision rate of 5 mm/y. Once the model results are consistent with the measured data, the calibration of hillslope processes follows. For given critical slope, diffusivity could be fitted to match the observed sediment discharge. Applying of surface evolution model to real DEM reveals specific problems which do not appear when working with synthetic landscapes. One of them is the noise of the satellite-measured topography. In particular, due to the non-vertical observation perspective, satellite may not be able to detect the bottom of the river channel, especially

  20. Implementation of a sliding-mode-based position sensorless drive for high-speed micro permanent-magnet synchronous motors.

    PubMed

    Chi, Wen-Chun; Cheng, Ming-Yang

    2014-03-01

    Due to issues such as limited space, it is difficult if it is not impossible to employ a position sensor in the drive control of high-speed micro PMSMs. In order to alleviate this problem, this paper analyzes and implements a simple and robust position sensorless field-oriented control method of high-speed micro PMSMs based on the sliding-mode observer. In particular, the angular position and velocity of the rotor of the high-speed micro PMSM are estimated using the sliding-mode observer. This observer is able to accurately estimate rotor position in the low speed region and guarantee fast convergence of the observer in the high speed region. The proposed position sensorless control method is suitable for electric dental handpiece motor drives where a wide speed range operation is essential. The proposed sensorless FOC method is implemented using a cost-effective 16-bit microcontroller and tested in a prototype electric dental handpiece motor. Several experiments are performed to verify the effectiveness of the proposed method.

  1. Undergraduate Laboratory Module for Implementing ELISA on the High Performance Microfluidic Platform.

    PubMed

    Giri, Basant; Peesara, Ravichander R; Yanagisawa, Naoki; Dutta, Debashis

    Implementing enzyme-linked immunosorbent assays (ELISA) in microchannels offers several advantages over its traditional microtiter plate-based format, including a reduced sample volume requirement, shorter incubation period, and greater sensitivity. Moreover, microfluidic ELISA platforms are inexpensive to fabricate and allow integration of analytical procedures, such as sample preconcentration, that further enhance the performance of the immunoassay. In view of the scientific potential of microfluidic ELISAs, inclusion of this technique into an undergraduate curriculum is valuable in preparing the next generation of scientists and engineers. Here, an experimental module is presented for this immunoassay method that can be completed in an undergraduate laboratory setting within two 3-h periods (including all incubation and data analyses procedures) using only a microliter of sample and reagents per assay. In addition to acquainting students with the microfluidic technology, the reported module provides training in quantitating ELISAs using the kinetic format of the assay. Furthermore, it offers a useful educational tool for introducing undergraduates to basic image analysis techniques, as well as signal-to-noise ratio and limit of detection calculations that are valuable in characterizing any analytical method.

  2. Undergraduate Laboratory Module for Implementing ELISA on the High Performance Microfluidic Platform

    PubMed Central

    Giri, Basant; Peesara, Ravichander R.; Yanagisawa, Naoki; Dutta, Debashis

    2015-01-01

    Implementing enzyme-linked immunosorbent assays (ELISA) in microchannels offers several advantages over its traditional microtiter plate-based format, including a reduced sample volume requirement, shorter incubation period, and greater sensitivity. Moreover, microfluidic ELISA platforms are inexpensive to fabricate and allow integration of analytical procedures, such as sample preconcentration, that further enhance the performance of the immunoassay. In view of the scientific potential of microfluidic ELISAs, inclusion of this technique into an undergraduate curriculum is valuable in preparing the next generation of scientists and engineers. Here, an experimental module is presented for this immunoassay method that can be completed in an undergraduate laboratory setting within two 3-h periods (including all incubation and data analyses procedures) using only a microliter of sample and reagents per assay. In addition to acquainting students with the microfluidic technology, the reported module provides training in quantitating ELISAs using the kinetic format of the assay. Furthermore, it offers a useful educational tool for introducing undergraduates to basic image analysis techniques, as well as signal-to-noise ratio and limit of detection calculations that are valuable in characterizing any analytical method. PMID:26052160

  3. Design and implementation of a highly integrated and automated in situ bioremediation system for petroleum hydrocarbons

    SciTech Connect

    Dey, J.C.; Rosenwinkel, P.; Norris, R.D.

    1996-12-31

    The proposed sale of an industrial property required that an environmental investigation be conducted as part of the property transfer agreement. The investigation revealed petroleum hydrocarbon compounds (PHCs) in the subsurface. Light nonaqueous phase liquids (LNAPLs) varsol (a gasoline like solvent), gasoline, and fuel oil were found across a three (3) acre area and were present as liquid phase PHCs, as dissolved phase PHCs, and as adsorbed phase PHCs in both saturated and unsaturated soils. Fuel oil was largely present in the unsaturated soils. Fuel oil was largely present in the unsaturated soils. Varsol represented the majority of the PHCs present. The presence of liquid phase PHCs suggested that any remedial action incorporate free phase recovery. The volatility of varsol and gasoline and the biodegradability of the PHCs present in the subsurface suggested that bioremediation, air sparging, and soil vapor extraction/bioventing were appropriate technologies for incorporation in a remedy. The imminent conversion of the impacted area to a retail facility required that any long term remedy be unobtrusive and require minimum activity across much of the impacted area. In the following sections the site investigation, selection and testing of remedial technologies, and design and implementation of an integrated and automated remedial system is discussed.

  4. Effects of High Dissolved Inorganic and Organic Carbon Availability on the Physiology of the Hard Coral Acropora millepora from the Great Barrier Reef

    PubMed Central

    Meyer, Friedrich W.; Vogel, Nikolas; Diele, Karen; Kunzmann, Andreas; Uthicke, Sven; Wild, Christian

    2016-01-01

    Coral reefs are facing major global and local threats due to climate change-induced increases in dissolved inorganic carbon (DIC) and because of land-derived increases in organic and inorganic nutrients. Recent research revealed that high availability of labile dissolved organic carbon (DOC) negatively affects scleractinian corals. Studies on the interplay of these factors, however, are lacking, but urgently needed to understand coral reef functioning under present and near future conditions. This experimental study investigated the individual and combined effects of ambient and high DIC (pCO2 403 μatm/ pHTotal 8.2 and 996 μatm/pHTotal 7.8) and DOC (added as Glucose 0 and 294 μmol L-1, background DOC concentration of 83 μmol L-1) availability on the physiology (net and gross photosynthesis, respiration, dark and light calcification, and growth) of the scleractinian coral Acropora millepora (Ehrenberg, 1834) from the Great Barrier Reef over a 16 day interval. High DIC availability did not affect photosynthesis, respiration and light calcification, but significantly reduced dark calcification and growth by 50 and 23%, respectively. High DOC availability reduced net and gross photosynthesis by 51% and 39%, respectively, but did not affect respiration. DOC addition did not influence calcification, but significantly increased growth by 42%. Combination of high DIC and high DOC availability did not affect photosynthesis, light calcification, respiration or growth, but significantly decreased dark calcification when compared to both controls and DIC treatments. On the ecosystem level, high DIC concentrations may lead to reduced accretion and growth of reefs dominated by Acropora that under elevated DOC concentrations will likely exhibit reduced primary production rates, ultimately leading to loss of hard substrate and reef erosion. It is therefore important to consider the potential impacts of elevated DOC and DIC simultaneously to assess real world scenarios, as

  5. Effects of High Dissolved Inorganic and Organic Carbon Availability on the Physiology of the Hard Coral Acropora millepora from the Great Barrier Reef.

    PubMed

    Meyer, Friedrich W; Vogel, Nikolas; Diele, Karen; Kunzmann, Andreas; Uthicke, Sven; Wild, Christian

    2016-01-01

    Coral reefs are facing major global and local threats due to climate change-induced increases in dissolved inorganic carbon (DIC) and because of land-derived increases in organic and inorganic nutrients. Recent research revealed that high availability of labile dissolved organic carbon (DOC) negatively affects scleractinian corals. Studies on the interplay of these factors, however, are lacking, but urgently needed to understand coral reef functioning under present and near future conditions. This experimental study investigated the individual and combined effects of ambient and high DIC (pCO2 403 μatm/ pHTotal 8.2 and 996 μatm/pHTotal 7.8) and DOC (added as Glucose 0 and 294 μmol L-1, background DOC concentration of 83 μmol L-1) availability on the physiology (net and gross photosynthesis, respiration, dark and light calcification, and growth) of the scleractinian coral Acropora millepora (Ehrenberg, 1834) from the Great Barrier Reef over a 16 day interval. High DIC availability did not affect photosynthesis, respiration and light calcification, but significantly reduced dark calcification and growth by 50 and 23%, respectively. High DOC availability reduced net and gross photosynthesis by 51% and 39%, respectively, but did not affect respiration. DOC addition did not influence calcification, but significantly increased growth by 42%. Combination of high DIC and high DOC availability did not affect photosynthesis, light calcification, respiration or growth, but significantly decreased dark calcification when compared to both controls and DIC treatments. On the ecosystem level, high DIC concentrations may lead to reduced accretion and growth of reefs dominated by Acropora that under elevated DOC concentrations will likely exhibit reduced primary production rates, ultimately leading to loss of hard substrate and reef erosion. It is therefore important to consider the potential impacts of elevated DOC and DIC simultaneously to assess real world scenarios, as

  6. Sustaining the utilization and high quality implementation of tested and effective prevention programs using the communities that care prevention system.

    PubMed

    Fagan, Abigail A; Hanson, Koren; Briney, John S; David Hawkins, J

    2012-06-01

    This paper describes the extent to which communities implementing the Communities That Care (CTC) prevention system adopt, replicate with fidelity, and sustain programs shown to be effective in reducing adolescent drug use, delinquency, and other problem behaviors. Data were collected from directors of community-based agencies and coalitions, school principals, service providers, and teachers, all of whom participated in a randomized, controlled evaluation of CTC in 24 communities. The results indicated significantly increased use and sustainability of tested, effective prevention programs in the 12 CTC intervention communities compared to the 12 control communities, during the active phase of the research project when training, technical assistance, and funding were provided to intervention sites, and 2 years following provision of such resources. At both time points, intervention communities also delivered prevention services to a significantly greater number of children and parents. The quality of implementation was high in both conditions, with only one significant difference: CTC sites were significantly more likely than control sites to monitor the quality of implementation during the sustainability phase of the project.

  7. Fertility of a high-altitude sheep model is compromised by deficiencies in both preovulatory follicle development and plasma LH availability.

    PubMed

    Parraguez, V H; Diaz, F; Cofré, E; Urquieta, B; De Los Reyes, M; Astiz, S; Gonzalez-Bulnes, A

    2014-12-01

    At high altitude, hypoxia and/or oxidative stress may compromise fertility. This study tested the relative effect of short- or long-term exposure to high-altitude hypobaric hypoxia and oxidative stress in sheep on preovulatory follicle dynamics and gonadotrophin secretion. Thus, growth dynamics, stereidogenic function and competence to ovulate of preovulatory follicles, as well as FSH and LH availability throughout the entire oestrous cycle, were compared among sheep native from low and high altitude, and sheep newcomers to high altitude. The results indicates that short-term exposure in sheep newcomers to high altitude has a deleterious effect on both the ovarian function (affecting preovulatory follicular development) and the pituitary function (diminishing plasma LH availability). On the other hand, there were no detected differences in the preovulatory follicular development in sheep adapted to high altitude for generations and, conversely, LH secretion was increased, which suggests an adaptive mechanism. The treatment with antioxidant agents during a relative short period for the time of folliculogenesis (approximately 1 month and a half) changed substantially the development of preovulatory follicles in short-term exposed sheep to similar patterns than in sheep native and living to both high and low altitude. These results highlight the role of oxidative stress in the detriment of the reproductive function in individuals recently exposed to high-altitude hypoxic environment.

  8. Implementation of a reduced rank square-root smoother for high resolution ocean data assimilation

    NASA Astrophysics Data System (ADS)

    Cosme, E.; Brankart, J.-M.; Verron, J.; Brasseur, P.; Krysta, M.

    Optimal smoothers enable the use of future observations to estimate the state of a dynamical system. In this paper, a square-root smoother algorithm is presented, extended from the Singular Evolutive Extended Kalman (SEEK) filter, a square-root Kalman filter routinely used for ocean data assimilation. With this filter algorithm, the smoother extension appears almost cost-free. A modified algorithm implementing a particular parameterization of model error is also described. The smoother is applied with an ocean circulation model in a double-gyre, 1/4° configuration, able to represent mid-latitude mesoscale dynamics. Twin experiments are performed: the true fields are drawn from a simulation at a 1/6° resolution, and noised. Then, altimetric satellite tracks and sparse vertical profiles of temperature are extracted to form the observations. The smoother is efficient in reducing errors, particularly in the regions poorly covered by the observations at the filter analysis time. It results in a significant reduction of the global error: the Root Mean Square Error in Sea Surface Height from the filter is further reduced by 20% by the smoother. The actual smoothing of the global error through time is also verified. Three essential issues are then investigated: (i) the time distance within which observations may be favourably used to correct the state estimates is found to be 8 days with our system. (ii) The impact of the model error parameterization is stressed. When this parameterization is spuriously neglected, the smoother can deteriorate the state estimates. (iii) Iterations of the smoother over a fixed time interval are tested. Although this procedure improves the state estimates over the assimilation window, it also makes the subsequent forecast worse than the filter in our experiment.

  9. Design and implementation of a narrow-band superconducting X-band diplexer with high isolation

    NASA Astrophysics Data System (ADS)

    Wang, Xiang; Wei, Bin; Zheng, Tianning; Cao, Bisong; Jiang, Linan; Chen, Jiabin

    2016-12-01

    This paper presents a high performance X-band diplexer with a 65 MHz bandwidth operating at central frequencies of 9.90 and 10.02 GHz. Outstanding six-pole channel filters with a high out-of-band rejection are realized by utilizing a double-folded resonator and suppressing nonadjacent couplings on the basis of coupling analysis to improve the filtering performance of the diplexer. Two types of diplexers are compared in terms of isolation and packaging box's influence. The T-type topology is better than Y-type, and its isolation exceeds 70 dB. Moreover, the return loss and insertion loss is better than 13 dB and 0.4 dB respectively. The measurements agree well with the simulations, demonstrating that a high performance X-band diplexer with a compact size can be realized by HTS film apart from waveguide structure.

  10. Pseudo-random single photon counting: a high-speed implementation

    PubMed Central

    Zhang, Qiang; Chen, Ling; Chen, Nanguang

    2010-01-01

    Pseudo-random single photon counting (PRSPC) is a new time-resolved optical measurement method which combines the spread spectrum time-resolved method with single photon counting. A pseudo-random bit sequence is used to modulate a continuous wave laser diode, while single photon counting is used to build up the optical signal in response to the modulated excitation. Periodic cross-correlation is performed to obtain the temporal profile of the subject of interest. Compared with conventional time-correlated single photon counting (TCSPC), PRSPC enjoys many advantages such as low cost and high count rate without compromising the sensitivity and time-resolution. In this paper, we report a PRSPC system that can be used for high-speed acquisition of the temporal point spread function of diffuse photons. It can reach a photon count rate as high as 3 Mcps (counts per second). Phantom experiments have been conducted to demonstrate the system performance. PMID:21258444

  11. Factors Influencing the Selection of the Systems Integration Organizational Model Type for Planning and Implementing Government High-Technology Programs

    NASA Technical Reports Server (NTRS)

    Thomas, Leann; Utley, Dawn

    2006-01-01

    While there has been extensive research in defining project organizational structures for traditional projects, little research exists to support high technology government project s organizational structure definition. High-Technology Government projects differ from traditional projects in that they are non-profit, span across Government-Industry organizations, typically require significant integration effort, and are strongly susceptible to a volatile external environment. Systems Integration implementation has been identified as a major contributor to both project success and failure. The literature research bridges program management organizational planning, systems integration, organizational theory, and independent project reports, in order to assess Systems Integration (SI) organizational structure selection for improving the high-technology government project s probability of success. This paper will describe the methodology used to 1) Identify and assess SI organizational structures and their success rate, and 2) Identify key factors to be used in the selection of these SI organizational structures during the acquisition strategy process.

  12. Performance Sensitivity Studies on the PIAA Implementation of the High-Contrast Imaging Testbed

    NASA Technical Reports Server (NTRS)

    Sidick, Erkin; Lou, John; Shaklan, Stuart; Levine, Marie

    2010-01-01

    This slide presentation reviews the sensitivity studies on the Phase-Induced Amplitude Apodization (PIAA), or pupil mapping using the High-Contrast Imaging Testbed (HCIT). PIAA is a promising technique in high-dynamic range stellar coronagraph. This presentation reports on the investigation of the effects of the phase and rigid-body errors of various optics on the narrowband contrast performance of the PIAA/HCIT hybrid system. The results have shown that the 2-step wavefront control method utilizing 2-DMs is quite effective in compensating the effects of realistic phase and rigid-body errors of various optics

  13. An Implementation of a Language Analyzer for the Very High Speed Integrated Circuit Hardware Description Language.

    DTIC Science & Technology

    1986-12-01

    butior. Statement A is correct. Per Lt. Col. Richard R . Gross, AFIT/G Accesion For NTIs CRA&M DTIC TAB E Unlannounced [_J Justification...these constructs seemed the ideal first r problem. 4.4 Two options were available for the resolution of this problem: the f ive major constructs could h...description, and thereby reduced overall development time. Create and use abstract data types. The term abstract data type is defined (e.g., Fairley

  14. Using magnetic coupling to implement 1H, 19F, 13C experiments in routine high resolution NMR probes

    NASA Astrophysics Data System (ADS)

    Bowyer, Paul; Finnigan, Jim; Marsden, Brian; Taber, Bob; Zens, Albert

    2015-12-01

    We report in this paper the design of 1H, 19F, 13C circuitry using magnetic coupling which can do on demand experiments where one of the three nuclei is observed and the other two are decoupled. The implementation of this circuitry in routine NMR probes is compared with capacitive coupling methods where it was found that by using magnetic coupling the performance of the routine NMR probe was not impacted by the addition of this circuitry. It is surmised that using this type of circuitry would be highly desirable for those chemists doing routine 19F NMR.

  15. Implementation of an Education Technology Policy in Namibia's High Schools: Through the Eyes of the Teacher

    ERIC Educational Resources Information Center

    Boer, Perien Joniell

    2012-01-01

    The purpose of this study was to explore how Namibian high school teachers experienced the ICT policy for education in their schools. This mixed methods sequential explanatory design consists of two distinct phases: quantitative followed by qualitative (Creswell & Plano Clark, 2011). Quantitative data collection involved the distribution and…

  16. Exploring Problem-Based Learning in the Context of High School Science: Design and Implementation Issues

    ERIC Educational Resources Information Center

    Goodnough, Karen; Cashion, Marie

    2006-01-01

    This paper reports on the experiences of a small collaborative inquiry group consisting of a high school science teacher, Deidre, and two university researchers, the authors of this paper, as they explored an active, inquiry-based approach to teaching and learning referred to as Problem-Based Learning or PBL (Barrows, 1994; Barrows & Tamblyn,…

  17. Implementing an Inexpensive and Accurate Introductory Gas Density Activity with High School Students

    ERIC Educational Resources Information Center

    Cunningham, W. Patrick; Joseph, Christopher; Morey, Samantha; Santos Romo, Ana; Shope, Cullen; Strang, Jonathan; Yang, Kevin

    2015-01-01

    A simplified activity examined gas density while employing cost-efficient syringes in place of traditional glass bulbs. The exercise measured the density of methane, with very good accuracy and precision, in both first-year high school and AP chemistry settings. The participating students were tasked with finding the density of a gas. The…

  18. Response-to-Intervention in High-Risk Preschools: Critical Issues for Implementation

    ERIC Educational Resources Information Center

    Ball, Carrie R.; Trammell, Beth A.

    2011-01-01

    This article summarizes the current knowledge of response-to-intervention (RTI) models in preschool settings, with an emphasis on evaluating the strengths and weaknesses of our current research base. Particular attention is given to the unique challenges of high-risk preschool settings. Presently, sufficient empirical support exists to begin…

  19. Development and Implementation of a Sport Psychology Program in an Urban High School

    ERIC Educational Resources Information Center

    Weissman, Michael

    2005-01-01

    This article is based on a dissertation of the author that was centered on the process of developing a sport psychology program at the high school level. The program was developed to address academic, mental, social, and emotional needs of student-athletes and coaches. This sport psychology program, which was developed in the Linden Public School…

  20. Implementing California's School Funding Formula: Will High-Need Students Benefit?

    ERIC Educational Resources Information Center

    Hill, Laura; Ugo, Iwunze

    2015-01-01

    The Local Control Funding Formula (LCFF) reformed California's K-12 school finance system. It replaced a patchwork of formulas and specific (or "categorical") programs with a focus on local control, funding equity, and additional support for the large share of students (63%) who are "high needs"--that is, low-income, English…

  1. Prisoners of Time: Implementing a Block Schedule in the High School.

    ERIC Educational Resources Information Center

    Mistretta, Gerald M.; Polansky, Harvey B.

    1997-01-01

    A committee comprised of six veteran teachers, the principal, and one parent initiated East Lyme (Connecticut) High School's search for a workable school schedule. The alternative-day block schedule featured semester and full-year course formats, 85-minute time blocks, a 45-minute lunch/club/activity period, and a closed campus. A survey found…

  2. Implementation of Web-Based Dynamic Assessment in Facilitating Junior High School Students to Learn Mathematics

    ERIC Educational Resources Information Center

    Wang, Tzu-Hua

    2011-01-01

    This research adopts the Graduated Prompting Assessment Module of the WATA system (GPAM-WATA) and applies it to the remedial teaching of junior high school mathematics. The theoretical basis of the development of GPAM-WATA is the idea of 'graduated prompt approach' proposed by Campione and Brown (1985; 1987, pp. 92-95). In GPAM-WATA, when…

  3. Development and Implementation of a New Attendance Policy at Napa High School.

    ERIC Educational Resources Information Center

    Feist, Ronald L.

    The attendance policy outlined in this document succeeded in increasing attendance in Napa High School, California. The program focused on student absences due to truancy, not illness, although many of the illness absences reported were due to other, not-so-legitimate causes. The attendance program utilized a direct relationship between the…

  4. Implementation of a High-Performance Cardiopulmonary Resuscitation Protocol at a Collegiate Emergency Medical Services Program

    ERIC Educational Resources Information Center

    Stefos, Kathryn A.; Nable, Jose V.

    2016-01-01

    Out-of-hospital cardiac arrest (OHCA) is a significant public health issue. Although OHCA occurs relatively infrequently in the collegiate environment, educational institutions with on-campus emergency medical services (EMS) agencies are uniquely positioned to provide high-quality resuscitation care in an expedient fashion. Georgetown University's…

  5. Development and Implementation of High School Chemistry Modules Using Touch-Screen Technologies

    ERIC Educational Resources Information Center

    Lewis, Maurica S.; Zhao, Jinhui; Montclare, Jin Kim

    2012-01-01

    Technology was employed to motivate and captivate students while enriching their in-class education. An outreach program is described that involved college mentors introducing touch-screen technology into a high school chemistry classroom. Three modules were developed, with two of them specifically tailored to encourage comprehension of molecular…

  6. Education through Occupations in American High Schools. Volume II. The Challenges of Implementing Curriculum Integration.

    ERIC Educational Resources Information Center

    Grubb, W. Norton, Ed.

    This book contains the following papers examining the challenges of integrating high school vocational and academic curricula to provide education through occupations: "Components of a Complex Reform" (W. Norton Grubb); "Integrating Vocational and Academic Education: Lessons from Early Innovators" (Kimberly Ramsey et al.);…

  7. Implementation of digital multiplexing for high resolution X-ray detector arrays.

    PubMed

    Sharma, P; Swetadri Vasan, S N; Titus, A H; Cartwright, A N; Bednarek, D R; Rudin, S

    2012-01-01

    We describe and demonstrate for the first time the use of the novel Multiple Module Multiplexer (MMMIC) for a 2×2 array of new electron multiplying charge coupled device (EMCCD) based x-ray detectors. It is highly desirable for x-ray imaging systems to have larger fields of view (FOV) extensible in two directions yet to still be capable of doing high resolution imaging over regions-of-interest (ROI). The MMMIC achieves these goals by acquiring and multiplexing data from an array of imaging modules thereby enabling a larger FOV, and at the same time allowing high resolution ROI imaging through selection of a subset of modules in the array. MMMIC also supports different binning modes. This paper describes how a specific two stage configuration connecting three identical MMMICs is used to acquire and multiplex data from a 2×2 array of EMCCD based detectors. The first stage contains two MMMICs wherein each MMMIC is getting data from two EMCCD detectors. The multiplexed data from these MMMICs is then forwarded to the second stage MMMIC in the similar fashion. The second stage that has only one MMMIC gives the final 12 bit multiplexed data from four modules. This data is then sent over a high speed Camera Link interface to the image processing computer. X-ray images taken through the 2×2 array of EMCCD based detectors using this two stage configuration of MMMICs are shown successfully demonstrating the concept.

  8. 76 FR 71353 - Notice of Availability of the Record of Decision for the DesertXpress Enterprises, LLC High-Speed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ... Bureau of Land Management Notice of Availability of the Record of Decision for the DesertXpress... Record of Decision (ROD) for the DesertXpress Enterprises, LLC High-Speed Passenger Train Project (Desert... ROD sets forth BLM's decision to issue a right-of-way (ROW) grant to DesertXpress Enterprises, LLC...

  9. Comparing the Effects of Commercially Available and Custom-Made Video Prompting for Teaching Cooking Skills to High School Students with Autism

    ERIC Educational Resources Information Center

    Mechling, Linda C.; Ayres, Kevin M.; Foster, Ashley L.; Bryant, Kathryn J.

    2013-01-01

    The study compared the effects of using commercially available and custom-made video prompts on the completion of cooking recipes by four high school age males with a diagnosis of autism. An adapted alternating treatments design with continuous baseline, comparison, final treatment, and best treatment condition was used to compare the two…

  10. A Comparative Study of Heavy Ion and Proton Induced Bit Error Sensitivity and Complex Burst Error Modes in Commercially Available High Speed SiGe BiCMOS

    NASA Technical Reports Server (NTRS)

    Marshall, Paul; Carts, Marty; Campbell, Art; Reed, Robert; Ladbury, Ray; Seidleck, Christina; Currie, Steve; Riggs, Pam; Fritz, Karl; Randall, Barb

    2004-01-01

    A viewgraph presentation that reviews recent SiGe bit error test data for different commercially available high speed SiGe BiCMOS chips that were subjected to various levels of heavy ion and proton radiation. Results for the tested chips at different operating speeds are displayed in line graphs.

  11. Delivering High-Quality Family Planning Services in Crisis-Affected Settings I: Program Implementation

    PubMed Central

    Curry, Dora Ward; Rattan, Jesse; Nzau, Jean Jose; Giri, Kamlesh

    2015-01-01

    ABSTRACT In 2012, about 43 million women of reproductive age experienced the effects of conflict. Provision of basic sexual and reproductive health services, including family planning, is a recognized right and need of refugees and internally displaced people, but funding and services for family planning have been inadequate. This article describes lessons learned during the first 2.5 years of implementing the ongoing Supporting Access to Family Planning and Post-Abortion Care in Emergencies (SAFPAC) initiative, led by CARE, which supports government health systems to deliver family planning services in 5 crisis-affected settings (Chad, Democratic Republic of the Congo, Djibouti, Mali, and Pakistan). SAFPAC's strategy focuses on 4 broad interventions drawn from public health best practices in more stable settings: competency-based training for providers, improved supply chain management, regular supervision, and community mobilization to influence attitudes and norms related to family planning. Between July 2011 and December 2013, the initiative reached 52,616 new users of modern contraceptive methods across the 5 countries (catchment population of 698,053 women of reproductive age), 61% of whom chose long-acting methods of implants or intrauterine devices. Prudent use of data to inform decision making has been an underpinning to the project's approach. A key approach to ensuring sustained ability to train and supervise new providers has been to build capacity in clinical skills training and supervision by establishing in-country training centers. In addition, monthly supervision using simple checklists has improved program and service quality, particularly with infection prevention procedures and stock management. We have generally instituted a “pull” system to manage commodities and other supplies, whereby health facilities place resupply orders as needed based on actual consumption patterns and stock-alert thresholds. Finally, reaching the community with

  12. Delivering high-quality family planning services in crisis-affected settings I: program implementation.

    PubMed

    Curry, Dora Ward; Rattan, Jesse; Nzau, Jean Jose; Giri, Kamlesh

    2015-02-04

    In 2012, about 43 million women of reproductive age experienced the effects of conflict. Provision of basic sexual and reproductive health services, including family planning, is a recognized right and need of refugees and internally displaced people, but funding and services for family planning have been inadequate. This article describes lessons learned during the first 2.5 years of implementing the ongoing Supporting Access to Family Planning and Post-Abortion Care in Emergencies (SAFPAC) initiative, led by CARE, which supports government health systems to deliver family planning services in 5 crisis-affected settings (Chad, Democratic Republic of the Congo, Djibouti, Mali, and Pakistan). SAFPAC's strategy focuses on 4 broad interventions drawn from public health best practices in more stable settings: competency-based training for providers, improved supply chain management, regular supervision, and community mobilization to influence attitudes and norms related to family planning. Between July 2011 and December 2013, the initiative reached 52,616 new users of modern contraceptive methods across the 5 countries (catchment population of 698,053 women of reproductive age), 61% of whom chose long-acting methods of implants or intrauterine devices. Prudent use of data to inform decision making has been an underpinning to the project's approach. A key approach to ensuring sustained ability to train and supervise new providers has been to build capacity in clinical skills training and supervision by establishing in-country training centers. In addition, monthly supervision using simple checklists has improved program and service quality, particularly with infection prevention procedures and stock management. We have generally instituted a "pull" system to manage commodities and other supplies, whereby health facilities place resupply orders as needed based on actual consumption patterns and stock-alert thresholds. Finally, reaching the community with mobilization

  13. Arbuscular mycorrhizal fungi altered the hypericin, pseudohypericin, and hyperforin content in flowers of Hypericum perforatum grown under contrasting P availability in a highly organic substrate.

    PubMed

    Lazzara, Silvia; Militello, Marcello; Carrubba, Alessandra; Napoli, Edoardo; Saia, Sergio

    2016-12-20

    St. John's Wort (Hypericum perforatum) is a perennial herb able to produce water-soluble active ingredients (a.i.), mostly in flowers, with a wide range of medicinal and biotechnological uses. However, information about the ability of arbuscular mycorrhizal fungi (AMF) to affect its biomass accumulation, flower production, and concentration of a.i. under contrasting nutrient availability is still scarce. In the present experiment, we evaluated the role of AMF on growth, flower production, and concentration of bioactive secondary metabolites (hypericin, pseudohypericin, and hyperforin) of H. perforatum under contrasting P availability. AMF stimulated the production of aboveground biomass under low P conditions and increased the production of root biomass. AMF almost halved the number of flowers per plant by means of a reduction of the number of flower-bearing stems per plant under high P availability and through a lower number of flowers per stem in the low-P treatment. Flower hyperforin concentration was 17.5% lower in mycorrhizal than in non-mycorrhizal plants. On the contrary, pseudohypericin and hypericin concentrations increased by 166.8 and 279.2%, respectively, with AMF under low P availability, whereas no effect of AMF was found under high P availability. These results have implications for modulating the secondary metabolite production of H. perforatum. However, further studies are needed to evaluate the competition for photosynthates between AMF and flowers at different nutrient availabilities for both plant and AM fungus.

  14. Performance of High-Reliability Space-Qualified Processors Implementing Software Defined Radios

    DTIC Science & Technology

    2014-03-01

    SCHOOL Monterey, California 93943- 5000 Ronald A. Route Douglas A. Hensler President Provost The report entitled “Performance of High...exceptions to this generalization have emerged recently. The U.S. Government has been sponsoring the OPERA project through which the Boeing Corp. has...N N Data- collection sink tile 2 Compute , 0 1NkX k≤ < − 13 We used the system interfaces to the underlying tile-to-tile communications functions

  15. Implementation of Both High-Speed Transmission and Quality of System for Internet Protocol Multicasting Services

    NASA Astrophysics Data System (ADS)

    Son, Byounghee; Park, Youngchoong; Nahm, Euiseok

    The paper introduces both high-speed transmission and quality of system to offer the Internet services on a HFC (Hybrid Fiber Coaxial) network. This utilizes modulating the phase and the amplitude to the signal of the IPMS (Internet Protocol Multicasting Service). An IP-cable transmitter, IP-cable modem, and IP-cable management servers that support 30-Mbps IPMS on the HFC were developed. The system provides a 21Mbps HDTV transporting stream on a cable TV network. It can sustain a clear screen for a long time.

  16. Implementation of a Gaussian Beam Laser and Aspheric Optics for High Spatial Resolution MALDI Imaging MS

    PubMed Central

    Zavalin, Andre; Yang, Junhai; Haase, Andreas; Holle, Armin; Caprioli, Richard

    2014-01-01

    We have investigated the use of a Gaussian beam laser for MALDI Imaging Mass Spectrometry to provide a precisely defined laser spot of 5 µm diameter on target using a commercial MALDI TOF instrument originally designed to produce a 20 µm diameter laser beam spot at its smallest setting. A Gaussian beam laser was installed in the instrument in combination with an aspheric focusing lens. This ion source produced sharp ion images at 5 µm spatial resolution with signals of high intensity as shown for images from thin tissue sections of mouse brain. PMID:24692046

  17. The implementation of high speed digital PSD in optically pumping magnetometers

    NASA Astrophysics Data System (ADS)

    Chen, Jun; Cheng, Defu; Zhou, Zhijian; Ma, Ming; Wang, Chao; Hu, Ruifan

    2017-01-01

    The 4He optically pumping magnetometer is a kind of high resolution instrument for measuring magnetic field intensity. Its response speed cannot meet the requirements in some experiments. By analyzing many factors, Phase Sensitive Detector (PSD) which is the key part of the lock-in amplifier processes data at a very slow speed is found. To improve its performance, this paper introduces a parallel digital phase sensitive detector based on coordinate rotation digital computer (CORDIC) algorithm. The cost time of the parallel digital phase sensitive detector is only 5.1% of the previous one. It can greatly enhance the response speed of the 4He optically pumping magnetometer.

  18. Implementation of the 2013 Astro-Science Workshop, a Hands-on High Altitude Ballooning Program at the Adler Planetarium

    NASA Astrophysics Data System (ADS)

    Ratliff, Gayle; Martynowycz, M. W.; Hammergren, M.

    2014-01-01

    For the past 7 years, high school students participating in the Astro-Science Workshop at the Adler Planetarium have been able to access the extreme environment of near space (approximately 30 km altitude) using high altitude balloons. Taking a hands-on approach the program has allowed students to design, build, and launch their own experiments with programming based at the Adler Planetarium. During flight, payloads are subjected to temperatures of around -65° C, atmospheric pressure of only 1% that at sea level, and cosmic radiation levels more than 60 times the surface background. In some ways, conditions at these altitudes are much like those at the surface of Mars, providing students with the opportunity to build and operate real-world analogs of interplanetary probes. We have found that this hands-on, student-driven research-based program is enhanced by implementing classroom and lab activities as well as by incorporating instruction and collaboration with research professionals currently active in the field of astronomy. We present the steps taken to implement the 2013 Astro-Science Workshop at the Adler Planetarium with a focus on daily instruction and operations planning and launch preparation.

  19. CHOUGH: implementation and performance of a high-order 4m AO demonstrator

    NASA Astrophysics Data System (ADS)

    Bharmal, Nazim A.; Basden, Alastair G.; Bourgenot, Cyril J.; Black, Martin; Dubbeldam, Cornelis M.; Henry, David M.; Hölck-Santibanez, Daniel; Morris, Timothy J.; Robertson, David J.; Schmoll, Jürgen; Talbot, Robert G.; Younger, Eddy J.; Myers, Richard M.

    2016-07-01

    CHOUGH is a small, fast project to provide an experimental on-sky high-order SCAO capability to the 4.2m WHT telescope. The basic goal has r0-sized sub- apertures with the aim of achieving high-Strehl ratios (> 0:5) in the visible (> 650 nm). It achieves this by including itself into the CANARY experiment: CHOUGH is mounted as a breadboard and intercepts the beam within CANARY via a periscope. In doing so, it takes advantage of the mature CANARY infrastructure, but add new AO capabilities. The key instruments that CHOUGH brings to CANARY are: an atmospheric dispersion compensator; a 32 × 32 (1000 actuator) MEMS deformable mirror; 31 × 31 wavefront sensor; and a complementary (narrow-field) imager. CANARY provides a 241-actuator DM, tip/tilt mirror, and comprehensive off-sky alignment facility together with a RTC. In this work, we describe the CHOUGH sub-systems: backbone, ADC, MEMS-DM, HOWFS, CAWS, and NFSI.

  20. Design and Implementation of a Characterization Test Rig for Evaluating High Bandwidth Liquid Fuel Flow Modulators

    NASA Technical Reports Server (NTRS)

    Saus, Joseph R.; Chang, Clarence T.; DeLaat, John C.; Vrnak, Daniel R.

    2010-01-01

    A test rig was designed and developed at the NASA Glenn Research Center (GRC) for the purpose of characterizing high bandwidth liquid fuel flow modulator candidates to determine their suitability for combustion instability control research. The test rig is capable of testing flow modulators at up to 600 psia supply pressure and flows of up to 2 gpm. The rig is designed to provide a quiescent flow into the test section in order to isolate the dynamic flow modulations produced by the test article. Both the fuel injector orifice downstream of the test article and the combustor are emulated. The effect of fuel delivery line lengths on modulator dynamic performance can be observed and modified to replicate actual fuel delivery systems. For simplicity, water is currently used as the working fluid, although future plans are to use jet fuel. The rig is instrumented for dynamic pressures and flows and a high-speed data system is used for dynamic data acquisition. Preliminary results have been obtained for one candidate flow modulator.

  1. COPE Method Implementation Program to Reduce Communication Apprehension Level in Full Day Yunior High School Students

    NASA Astrophysics Data System (ADS)

    Prasetyo, A. R.

    2017-02-01

    This study was aimed to explore the effect of COPE method to reduce communication apprehension level of students in Early Adolescence who become Full Day Junior High School students. Full Day Junior High School students, especially in Surabaya coastal area, have more demands to develop the communication aspects such as group discussions and presentations and extracurricular activities. Higher demands to develop such aspects of communication may cause them to experience communication apprehension. The subject was Full Day School students totaling 31 students. The design of the research was experimental design. The experimental method used was a non-randomized pretest posttest control group design and purposive sampling was also used. COPE method is a process that consists of four main stages where people are trying to deal with and control of stressful situations as a result of the problem being faced by conducting cognitive and behavioral changes. Four main stages COPE method is Calming the nervous system, Originating an imaginative plan, Persisting in the face of obstacles and failure, and Evaluating and adjusting the plan. Results of quantitative analysis based on U-Mann Whitney Test shows significant effect on the COPE Method to decrease anxiety levels of communication (0.000 <0.005).

  2. Spatially-discretized high-temperature approximations and theirO(N) implementation on a grid

    SciTech Connect

    Predescu, Cristian

    2006-10-01

    We consider the problem of performing imaginary-time propagation of wavefunctions on a grid. We demonstrate that spatially-continuous high-temperature approximations can be discretized in such a way that their convergence order is preserved. Requirements of minimal computational work and reutilization of data then uniquely determine the optimal grid, quadrature technique, and propagation method. It is shown that the optimal propagation technique is O(N) with respect to the grid size. The grid technique is utilized to compare the Monte Carlo efficiency of the Trotter-Suzuki approximation against a recently introduced fourth-order high-temperature approximation, while circumventing the issue of statistical noise, which usually prevents such comparisons from being carried out. We document the appearance of a systematic bias in the Monte Carlo estimators that involve temperature differentiation of the density matrix, bias that is due to the dependence of the eigenvalues on the inverse temperature. This bias is negotiated more successfully by the short-time approximations having higher convergence order, leading to non-trivial computational savings.

  3. High irradiance increases NH(4)(+) tolerance in Pisum sativum: Higher carbon and energy availability improve ion balance but not N assimilation.

    PubMed

    Ariz, Idoia; Artola, Ekhiñe; Asensio, Aaron Cabrera; Cruchaga, Saioa; Aparicio-Tejo, Pedro María; Moran, Jose Fernando

    2011-07-01

    The widespread use of NO(3)(-) fertilization has had a major ecological impact. NH(4)(+) nutrition may help to reduce this impact, although high NH(4)(+) concentrations are toxic for most plants. The underlying tolerance mechanisms are not yet fully understood, although they are thought to include the limitation of C, the disruption of ion homeostasis, and a wasteful NH(4)(+) influx/efflux cycle that carries an extra energetic cost for root cells. In this study, high irradiance (HI) was found to induce a notable tolerance to NH(4)(+) in the range 2.5-10mM in pea plants by inducing higher C availability, as shown by carbohydrate content. This capacity was accompanied by a general lower relative N content, indicating that tolerance is not achieved through higher net N assimilation on C-skeletons, and it was also not attributable to increased GS content or activity in roots or leaves. Moreover, HI plants showed higher ATP content and respiration rates. This extra energy availability is related to the internal NH(4)(+) content regulation (probably NH(4)(+) influx/efflux) and to an improvement of the cell ionic balance. The limited C availability at lower irradiance (LI) and high NH(4)(+) resulted in a series of metabolic imbalances, as reflected in a much higher organic acid content, thereby suggesting that the origin of the toxicity in plants cultured at high NH(4)(+) and LI is related to their inability to avoid large-scale accumulation of the NH(4)(+) ion.

  4. Implementation of micro-ball nanodiamond anvils for high-pressure studies above 6Mbar

    NASA Astrophysics Data System (ADS)

    Dubrovinsky, Leonid; Dubrovinskaia, Natalia; Prakapenka, Vitali B.; Abakumov, Artem M.

    2012-10-01

    Since invention of the diamond anvil cell technique in the late 1950s for studying materials at extreme conditions, the maximum static pressure generated so far at room temperature was reported to be about 400GPa. Here we show that use of micro-semi-balls made of nanodiamond as second-stage anvils in conventional diamond anvil cells drastically extends the achievable pressure range in static compression experiments to above 600GPa. Micro-anvils (10-50μm in diameter) of superhard nanodiamond (with a grain size below ~50nm) were synthesized in a large volume press using a newly developed technique. In our pilot experiments on rhenium and gold we have studied the equation of state of rhenium at pressures up to 640GPa and demonstrated the feasibility and crucial necessity of the in situ ultra high-pressure measurements for accurate determination of material properties at extreme conditions.

  5. Implementing SPAM into STMAS: A net sensitivity improvement in high-resolution NMR of quadrupolar nuclei

    NASA Astrophysics Data System (ADS)

    Amoureux, J. P.; Delevoye, L.; Fink, G.; Taulelle, F.; Flambard, A.; Montagne, L.

    2005-08-01

    Gan and Kwak recently introduced two new tools for high-resolution 2D NMR methods applied to quadrupolar nuclei: double-quantum filtering in STMAS (DQF-STMAS) and the soft-pulse added mixing (SPAM) idea. Double-quantum filtering suppresses all undesired signals in the STMAS method with limited loss in sensitivity. With SPAM, all pathways are added constructively after the second hard-pulse instead of using a single pathway as previously. Here, the sensitivity, advantages and drawbacks of DQF-STMAS are compared to 3QMAS. Additionally, SPAM can be included into DQF-STMAS method, resulting in a net sensitivity gain with respect to 3QMAS of ca. 10-15.

  6. Implementing SPAM into STMAS: a net sensitivity improvement in high-resolution NMR of quadrupolar nuclei.

    PubMed

    Amoureux, J P; Delevoye, L; Fink, G; Taulelle, F; Flambard, A; Montagne, L

    2005-08-01

    Gan and Kwak recently introduced two new tools for high-resolution 2D NMR methods applied to quadrupolar nuclei: double-quantum filtering in STMAS (DQF-STMAS) and the soft-pulse added mixing (SPAM) idea. Double-quantum filtering suppresses all undesired signals in the STMAS method with limited loss in sensitivity. With SPAM, all pathways are added constructively after the second hard-pulse instead of using a single pathway as previously. Here, the sensitivity, advantages and drawbacks of DQF-STMAS are compared to 3QMAS. Additionally, SPAM can be included into DQF-STMAS method, resulting in a net sensitivity gain with respect to 3QMAS of ca. 10-15.

  7. Blue-Coloured Highly Efficient Dye-Sensitized Solar Cells by Implementing the Diketopyrrolopyrrole Chromophore

    PubMed Central

    Yum, Jun-Ho; Holcombe, Thomas W.; Kim, Yongjoo; Rakstys, Kasparas; Moehl, Thomas; Teuscher, Joel; Delcamp, Jared H.; Nazeeruddin, Mohammed K.; Grätzel, Michael

    2013-01-01

    The paradigm shift in dye sensitized solar cells (DSCs) – towards donor- π bridge-acceptor (D-π-A) dyes – increases the performances of DSCs and challenges established design principles. Framed by this shifting landscape, a series of four diketopyrrolopyrrole (DPP)-based sensitizers utilizing the donor-chromophore-anchor (D-C-A) motif were investigated computationally, spectroscopically, and fabricated by systematic evaluation of finished photovoltaic cells. In all cases, the [Co(bpy)3]3+/2+ redox-shuttle afforded superior performance compared to I3−/I−. Aesthetically, careful molecular engineering of the DPP chromophore yielded the first example of a high-performance blue DSC – a challenge unmet since the inception of this photovoltaic technology: DPP17 yields over 10% power conversion efficiency (PCE) with the [Co(bpy)3]3+/2+ electrolyte at full AM 1.5 G simulated sun light. PMID:23945746

  8. Bioflocculating high-rate algal ponds: Control and implementation of an innovative wastewater treatment technology

    SciTech Connect

    Hall, T.W.

    1989-01-01

    High Rate Algal Ponds (HRPs) are multi-channel racetrack designs 0.2-0.5 meters deep, with pump or paddlewheel mixing, operated at 2-10 days detention time. HRPs produce higher algal concentrations (200-300 mg/L) than conventional oxidation ponds, requiring effluent algal removal to meet discharge limits. This study investigated the long-term performance of bioflocculation and sedimentation for HRP algal removal. Thirteen experiments were conducted between April 1980 and November 1982 using two 0.1 ha paddlewheel mixed HRPs at the University of California at Berkeley's Sanitary Engineering and Environmental Health Research Laboratory. Most experiments were conducted at 35 cm depth, with hydraulic loading varied seasonally to maintain settleability in response to changing insolation. Continuous 12 cm/sec paddlewheel mixing with consistent primary effluent hydraulic loading (4-11 cm/day) and sunlight loading (30-60 Kcal/L) were essential for maintaining high settleability. Bioflocculation and increased settleability were able to be induced in non-settleable ponds within several days to a few weeks after 12 cm/sec continuous paddlewheel mixing was started. Variable hydraulic loading temporarily decreases HRP settleability. Mixed HRPs achieved over 90% 24 hour TSS removals (11 mg/L) during 83 weeks of stable operation versus less than 50% (77 mg/L) for unmixed HRPS. Settling column removals reached 48% in 30 minutes (60 cm/hr) and 69% in 120 minutes under stable operational conditions. Algal morphology and settleability varied with operational and climatic conditions, with colonial Micractinium and Scenedesmus dominant. Unmixed HRPs produced minimally settleable colonies.

  9. The BaBar LST Detector High Voltage System: Design And Implementation

    SciTech Connect

    Benelli, G.; Honscheid, K.; Lewis, E.A.; Regensburger, J.J.; Smith, D.S.; /Ohio State U.

    2006-08-18

    In 2004, the first two sextants of the new Limited Streamer Tube (LST) detector were installed in the BABAR experiment to replace the ageing Resistive Plate Chambers (RPCs) as active detectors for the BABAR Instrumented Flux Return (IFR) muon system. Each streamer tube of the new detector consists of 8 cells. The cell walls are coated with graphite paint and a 100 {micro}m wire forms the anode. These wires are coupled in pairs inside the tubes resulting in 4 independent two-cell segments per LST. High voltage (HV) is applied to the 4 segments through a custom connector that also provides the decoupling capacitor to pick up the detector signals from the anode wires. The BABAR LST detector is operated at 5.5 kV. The high voltage system for the LST detector was designed and built at The Ohio State University (OSU HVPS). Each of the 25 supplies built for BaBar provides 80 output channels with individual current monitoring and overcurrent protection. For each group of 20 channels the HV can be adjusted between 0 and 6 kV. A 4-fold fan-out is integrated in the power supplies to provide a total of 320 outputs. The power supplies are controlled through built-in CANbus and Ethernet (TCP/IP) interfaces. In this presentation we will discuss the design and novel features of the OSU HVPS system and its integration into the BABAR EPICS detector control framework. Experience with the supplies operation during the LST extensive quality control program and their performance during the initial data taking period will be discussed.

  10. Highly efficient and exact method for parallelization of grid-based algorithms and its implementation in DelPhi.

    PubMed

    Li, Chuan; Li, Lin; Zhang, Jie; Alexov, Emil

    2012-09-15

    The Gauss-Seidel (GS) method is a standard iterative numerical method widely used to solve a system of equations and, in general, is more efficient comparing to other iterative methods, such as the Jacobi method. However, standard implementation of the GS method restricts its utilization in parallel computing due to its requirement of using updated neighboring values (i.e., in current iteration) as soon as they are available. Here, we report an efficient and exact (not requiring assumptions) method to parallelize iterations and to reduce the computational time as a linear/nearly linear function of the number of processes or computing units. In contrast to other existing solutions, our method does not require any assumptions and is equally applicable for solving linear and nonlinear equations. This approach is implemented in the DelPhi program, which is a finite difference Poisson-Boltzmann equation solver to model electrostatics in molecular biology. This development makes the iterative procedure on obtaining the electrostatic potential distribution in the parallelized DelPhi several folds faster than that in the serial code. Further, we demonstrate the advantages of the new parallelized DelPhi by computing the electrostatic potential and the corresponding energies of large supramolecular structures.

  11. Highly efficient and exact method for parallelization of grid-based algorithms and its implementation in DelPhi

    PubMed Central

    Li, Chuan; Li, Lin; Zhang, Jie; Alexov, Emil

    2012-01-01

    The Gauss-Seidel method is a standard iterative numerical method widely used to solve a system of equations and, in general, is more efficient comparing to other iterative methods, such as the Jacobi method. However, standard implementation of the Gauss-Seidel method restricts its utilization in parallel computing due to its requirement of using updated neighboring values (i.e., in current iteration) as soon as they are available. Here we report an efficient and exact (not requiring assumptions) method to parallelize iterations and to reduce the computational time as a linear/nearly linear function of the number of CPUs. In contrast to other existing solutions, our method does not require any assumptions and is equally applicable for solving linear and nonlinear equations. This approach is implemented in the DelPhi program, which is a finite difference Poisson-Boltzmann equation solver to model electrostatics in molecular biology. This development makes the iterative procedure on obtaining the electrostatic potential distribution in the parallelized DelPhi several folds faster than that in the serial code. Further we demonstrate the advantages of the new parallelized DelPhi by computing the electrostatic potential and the corresponding energies of large supramolecular structures. PMID:22674480

  12. High Speed Civil Transport Aircraft Simulation: Reference-H Cycle 1, MATLAB Implementation

    NASA Technical Reports Server (NTRS)

    Sotack, Robert A.; Chowdhry, Rajiv S.; Buttrill, Carey S.

    1999-01-01

    The mathematical model and associated code to simulate a high speed civil transport aircraft - the Boeing Reference H configuration - are described. The simulation was constructed in support of advanced control law research. In addition to providing time histories of the dynamic response, the code includes the capabilities for calculating trim solutions and for generating linear models. The simulation relies on the nonlinear, six-degree-of-freedom equations which govern the motion of a rigid aircraft in atmospheric flight. The 1962 Standard Atmosphere Tables are used along with a turbulence model to simulate the Earth atmosphere. The aircraft model has three parts - an aerodynamic model, an engine model, and a mass model. These models use the data from the Boeing Reference H cycle 1 simulation data base. Models for the actuator dynamics, landing gear, and flight control system are not included in this aircraft model. Dynamic responses generated by the nonlinear simulation are presented and compared with results generated from alternate simulations at Boeing Commercial Aircraft Company and NASA Langley Research Center. Also, dynamic responses generated using linear models are presented and compared with dynamic responses generated using the nonlinear simulation.

  13. Dissipative particle dynamics for systems with high density of charges: Implementation of electrostatic interactions

    NASA Astrophysics Data System (ADS)

    Gavrilov, A. A.; Chertovich, A. V.; Kramarenko, E. Yu.

    2016-11-01

    In this work, we study the question of how to introduce electrostatic interactions in dissipative particle dynamics (DPD) method in order to correctly reproduce the properties of systems with high density of charges, including those with inhomogeneous charge distribution. To this end, we formulate general requirements for the electrostatic force in DPD and propose a new functional form of the force which suits better for satisfying these requirements than the previously used ones. In order to verify the proposed model, we study the problem of a single polyelectrolyte chain collapse and compare the results with molecular dynamics (MD) simulations in which the exact Coulomb force is used. We show that an excellent quantitative agreement between MD and DPD models is observed if the length parameter D of the proposed electrostatic force is chosen properly; the recommendations concerning the choice of this parameter value are given based on the analysis of a polyelectrolyte chain collapse behavior. Finally, we demonstrate the applicability of DPD with the proposed electrostatic force to studying microphase separation phenomenon in polyelectrolyte melts and show that the same values of D as in the case of single chain collapse should be used, thus indicating universality of the model. Due to the charge correlation attraction, a long-range order in such melts can be observed even at zero Flory-Huggins parameter.

  14. Development and the Implementation of High-Temperature Reliable Heaters in Plasma Spray Technology

    NASA Astrophysics Data System (ADS)

    Prudenziati, Maria

    2008-06-01

    Many problems have been encountered during development of reliable high-temperature heaters by means of atmospheric plasma spray and procedures commonly adopted in thermal spray technology, especially due to poor steel substrate corrosion resistance, notably affected by grit-blasting operations, but also deriving from contamination of insulating layers, dielectric arcs, and failures due to hot spots in the heating elements. While seeking the origin of these problems, a close scrutiny of every single step of the preparation process and analyses of the coatings were carried out using laser confocal scanning microscopy, optical and electronic microscopy, fluorescence analysis, X-ray diffraction, and ancillary techniques. The electrical properties of both alumina layers and metal strips prepared with Ni, NiCr, NiAl commercial powders for the heating elements were studied and cross-related to the failures in the heaters. The article reports the main results of these investigations, delineates the innovations introduced to overcome or circumvent the problems, and underlines the distinct characteristics of new heaters, whose reliability has been proven up to now with temperatures of up to 600 °C in air.

  15. Reflections on implementing several models of teaching in a high school biology class

    NASA Astrophysics Data System (ADS)

    Baldwin, Michael E.

    This research investigates the challenges faced in enacting instructional models that previous research has found to foster student learning. In order to complete this study, the researcher documented, through a strategy of reflective practice, his return to teaching high school science after having served for a time as a science specialist and instructional coach. The study develops quality personal insights and questions that may be used by other educators and researchers to investigate the enactment of these different models and strategies. The research is limited to the spring of the 2010 school year and use notes, journals, and planner documents from the 2008--2009 school year. In order to appreciate complex interactions, triangulation was made through dovetailing personal observations with requested observations of the campus assistant principal, the district science specialist, and an out of district observer. Also, a short questionnaire administered to the students in these classes. Throughout this study, the researcher demonstrates that it is feasible to use these models. However, such external factors as imposed curriculum and standardized testing play a large role in everyday decision making of this particular teacher. The sheer amount of content to be covered under the Texas Essential Knowledge and Skills (TEKS) also influenced instructional decisions that were made. Choices about what strategy to use resided mainly within the teacher/researcher and were governed and affected mostly by his interactions with students and professional judgments about what would both bolster student understanding and help students score well on the Texas Assessment of Knowledge and Skills (TAKS).

  16. A display module implemented by the fast high-temperatue response of carbon nanotube thin yarns.

    PubMed

    Wei, Yang; Liu, Peng; Jiang, Kaili; Fan, Shoushan

    2012-05-09

    Suspending superaligned multiwalled carbon nanotube (MWCNT) films were processed into CNT thin yarns, about 1 μm in diameter, by laser cutting and an ethanol atomization bath treatment. The fast high-temperature response under a vacuum was revealed by monitoring the incandescent light with a photo diode. The thin yarns can be electrically heated up to 2170 K in 0.79 mS, and the succeeding cool-down time is 0.36 mS. The fast response is attributed to the ultrasmall mass of the independent single yarn, large radiation coefficient, and improved thermal conductance through the two cool ends. The millisecond response time makes it possible to use the visible hot thin yarns as light-emitting elements of an incandescent display. A fully sealed display with 16 × 16 matrix was successfully fabricated using screen-printed thick electrodes and CNT thin yarns. It can display rolling characters with a low power consumption. More applications can be further developed based on the addressable CNT thermal arrays.

  17. Feasibility and cost analysis of implementing high intensity aphasia clinics within a sub-acute setting.

    PubMed

    Wenke, Rachel; Lawrie, Melissa; Hobson, Tania; Comben, Wendy; Romano, Michelle; Ward, Elizabeth; Cardell, Elizabeth

    2014-06-01

    The current study explored the clinical feasibility and costs of embedding three different intensive service delivery models for aphasia treatment (computer, group therapy, and therapy with a speech pathology therapy assistant) within three sub-acute facilities. The study employed a two cohort comparison design, with the first cohort (n = 22) receiving the standard service of treatment currently offered. This treatment was delivered by a speech-language pathologist and involved on average 3 hours of treatment/week over 8 weeks. Participants in the second cohort (n = 31) received one of the three intensive treatment models providing up to 9 hours of therapy/week for 11 weeks. Organizational data was collected throughout treatment, with participant, caregiver, and clinician satisfaction with the intensive models also being measured. Participants completed the spoken language production sub-tests and the Disability Questionnaire of the Comprehensive Aphasia Test (CAT) pre- and post-treatment. All intensive models yielded high participant attendance, satisfaction, and significant improvements to the CAT sub-tests. The pro-rata cost of providing treatment per hour per client for the computer and group therapy models was found to be ˜ 30% cheaper compared to the standard service. The outcomes support the potential feasibility of embedding the different models into sub-acute facilities to enhance client access to intensive treatment for aphasia.

  18. GPU Implementation of Two-Dimensional Rayleigh-Benard Code with High Resolution and Extremely High Rayleigh Number

    NASA Astrophysics Data System (ADS)

    Gonzalez, C. M.; Sanchez, D. A.; Yuen, D. A.; Wright, G. B.; Barnett, G. A.

    2010-12-01

    As computational modeling became prolific throughout the physical sciences community, newer and more efficient ways of processing large amounts of data needed to be devised. One particular method for processing such large amounts of data arose in the form of using a graphics processing unit (GPU) for calculations. Computational scientists were attracted to the GPU as a computational tool as the performance, growth, and availability of GPUs over the past decade increased. Scientists began to utilize the GPU as the sole workhorse for their brute force calculations and modeling. The GPUs, however, were not originally designed for this style of use. As a result, difficulty arose when trying to find a use for the GPU from a scientific standpoint. A lack of parallel programming routines was the main culprit behind the difficulty in programming with a GPU, but with time and a rise in popularity, NVIDIA released a proprietary architecture named Fermi. The Fermi architecture, when used in conjunction with development tools such as CUDA, allowed the programmer easier access to routines that made parallel programming with the NVIDIA GPUs an ease. This new architecture enabled the programmer full access to faster memory, double-precision support, and large amounts of global memory at their fingertips. Our model was based on using a second-order, spatially correct finite difference method and a third order Runge-Kutta time-stepping scheme for studying the 2D Rayleigh-Benard code. The code extensively used the CUBLAS routines to do the heavy linear algebra calculations. The calculations themselves were completed using a single GPU, the NVDIA C2070 Fermi, which boasts 6 GB of global memory. The overall scientific goal of our work was to apply the Tesla C2070's computing potential to achieve an onset of flow reversals as a function of increasing large Rayleigh numbers. Previous investigations were successful using a smaller grid size of 1000x1999 and a Rayleigh number of 10^9. The

  19. The Value of High Resolution Forest Canopy Maps for Implementing Carbon Sequestration Programs in Maryland

    NASA Astrophysics Data System (ADS)

    Brown, M. E.; Abbott, P. C.; Hittich, R.; Dubayah, R.

    2015-12-01

    As part of the NASA Carbon Monitoring System (CMS) Program, the University of Maryland has produced 1m resolution forest canopy cover and height maps that have been provided to the State of Maryland. The project used existing, wall-to-wall airborne lidar coverage combined with other remote sensing and field datasets to produce countywide maps of carbon stocks and their uncertainties at 30 m resolution as well as the 1m canopy maps. In this paper, we examine what purposes we identified for the data for decision making in climate mitigation, what use it has already seen, and what potential there is in the future for using the data. The State of Maryland has three programs focused on maintaining or increasing forest cover as part of its Greenhouse Gas Emissions Reduction Program (GHGRP) program enacted in 2012, including Woodland Incentive Program (WIP), the Lawn to Woodland Initiative (L2W), and the Environmental Quality Incentives Program (EQIP). Forest canopy data from CMS were examined the prospects for both adoption and carbon sequestration of these three initiatives, and their effects on the overall success of the GHGRP. We found that it was difficult it is to pin down "value" that is directly attributable to the data, although we found the data to be important in recognizing the nature and extent of the carbon problem, and in identifying potential solutions to addressing the problem. As in many decision-making contexts, having high quality, accurate data on forest cover is necessary but not sufficient for effective, affordable programs that lead to carbon sequestration in the state.

  20. First Year K-12 Teachers as High Leverage Point to Implement GEMS Space Science Curriculum Sequence

    NASA Astrophysics Data System (ADS)

    Slater, Timothy F.; Mendez, B. J.; Schultz, G.; Wierman, T.

    2013-01-01

    The recurring challenge for curriculum developers is how to efficiently prepare K-12 classroom teachers to use new curricula. First-year teachers, numbering nearly 250,000 in the US each year, have the greatest potential to impact the largest number of students because they have potential to be in the classroom for thirty years. At the same time, these novice teachers are often the most open minded about adopting curricular innovation because they are not yet deeply entrenched in existing practices. To take advantage of this high leverage point, a collaborative of space scientists and science educators at the University of California, Berkeley’s Lawrence Hall of Science and Center for Science Education at the Space Sciences Laboratory with experts from the Astronomical Society of the Pacific, the University of Wyoming, and the CAPER Center for Astronomy & Physics Education experimented with a unique professional development model focused on helping master teachers work closely with pre-service teachers during their student teaching internship field experience. The Advancing Mentor and Novice Teachers in Space Science (AMANTISS) team first identified master teachers who supervise novice, student teachers and trained these master teachers to use the GEMS Space Science Curriculum Sequence. Then, these master teachers were mentored in coaching interning student teachers assigned to them in using GEMS materials. Evaluation showed that novice teachers mentored by the master teachers felt knowledgeable after teaching the GEMS units. However, they seemed relatively less confident about the solar system and objects beyond the solar system. Overall, mentees felt strongly at the end of the year that they have acquired good strategies for teaching the various topics, suggesting that the support they received while teaching and working with a mentor was of real benefit to them. Funding provided in part by NASA ROSES AMANTISS NNX09AD51G

  1. Analyzing social experiments as implemented: A reexamination of the evidence from the HighScope Perry Preschool Program.

    PubMed

    Heckman, James; Moon, Seong Hyeok; Pinto, Rodrigo; Savelyev, Peter; Yavitz, Adam

    2010-01-01

    Social experiments are powerful sources of information about the effectiveness of interventions. In practice, initial randomization plans are almost always compromised. Multiple hypotheses are frequently tested. "Significant" effects are often reported with p-values that do not account for preliminary screening from a large candidate pool of possible effects. This paper develops tools for analyzing data from experiments as they are actually implemented.We apply these tools to analyze the influential HighScope Perry Preschool Program. The Perry program was a social experiment that provided preschool education and home visits to disadvantaged children during their preschool years. It was evaluated by the method of random assignment. Both treatments and controls have been followed from age 3 through age 40.Previous analyses of the Perry data assume that the planned randomization protocol was implemented. In fact, as in many social experiments, the intended randomization protocol was compromised. Accounting for compromised randomization, multiple-hypothesis testing, and small sample sizes, we find statistically significant and economically important program effects for both males and females. We also examine the representativeness of the Perry study.

  2. Preventing Perinatal Depression in High Risk Women: Moving the Mothers and Babies Course from Clinical Trials to Community Implementation.

    PubMed

    Le, Huynh-Nhu; Perry, Deborah F; Mendelson, Tamar; Tandon, S Darius; Muñoz, Ricardo F

    2015-10-01

    A growing research literature highlights the public health need for preventive interventions to reduce symptoms and incidence of perinatal depression among vulnerable populations. The Mothers and Babies (MB) course is a cognitive-behavioral intervention designed to teach mood regulation skills to English- and Spanish-speaking low-income women at high risk for perinatal depression. We describe the development of the MB course and evaluate the extent to which research findings support efficacy, effectiveness, and dissemination based on the Society for Prevention Research Standards Committee's standards of evidence. Our review of research and implementation activities suggests that the MB intervention demonstrates promising evidence for efficacy in reducing depressive symptoms; empirical support for prevention of major depressive episodes is still preliminary. Work is in progress to evaluate program effectiveness and prepare for broad dissemination and implementation. The MB course shows promise as an intervention for low-income women at risk for perinatal mood issues. Spanish and English intervention materials have been developed that can be delivered in different settings (hospitals, home visiting), in different dosages (6, 8, or 12 sessions), and via different modalities (group, individual). Evaluating the MB course against current standards is intended to inform other prevention intervention development research.

  3. Design Implementation and Testing of a VLSI High Performance ASIC for Extracting the Phase of a Complex Signal

    NASA Astrophysics Data System (ADS)

    Altmeyer, Ronald C.

    2002-09-01

    This thesis documents the research, circuit design, and simulation testing of a VLSI (Very Large Scale Integration) ASIC which extracts phase angle information from a complex sampled signal using the arctangent relationship: (phi=tan/-1 (Q/1). Specifically, the circuit will convert the In-Phase and Quadrature terms into their corresponding phase angle. The design specifications were to implement the design in CMOS (Complementary Metal Oxide Semiconductors) technology with a minimum transistor count and ability to operate at a clock frequency of 700 MHz. Research on the arctangent function was performed to determine mathematical calculation methods and the CORDIC method was chosen to achieve the stated design specifications. MATLAB simulations were used to calculate and verify accuracy and to implement Quine-McClusky logic minimization. T-SPICE netlists were generated and simulations were run to determine transistor and circuit electrical operation and timing. Finally, overall circuit logic functionality of all possible input combinations was completed using a VHDL (VHSIC(Very High Speed Integrated Circuit) Hardware Description Language) simulation program.

  4. Analyzing social experiments as implemented: A reexamination of the evidence from the HighScope Perry Preschool Program

    PubMed Central

    Heckman, James; Moon, Seong Hyeok; Pinto, Rodrigo; Savelyev, Peter; Yavitz, Adam

    2012-01-01

    Social experiments are powerful sources of information about the effectiveness of interventions. In practice, initial randomization plans are almost always compromised. Multiple hypotheses are frequently tested. “Significant” effects are often reported with p-values that do not account for preliminary screening from a large candidate pool of possible effects. This paper develops tools for analyzing data from experiments as they are actually implemented. We apply these tools to analyze the influential HighScope Perry Preschool Program. The Perry program was a social experiment that provided preschool education and home visits to disadvantaged children during their preschool years. It was evaluated by the method of random assignment. Both treatments and controls have been followed from age 3 through age 40. Previous analyses of the Perry data assume that the planned randomization protocol was implemented. In fact, as in many social experiments, the intended randomization protocol was compromised. Accounting for compromised randomization, multiple-hypothesis testing, and small sample sizes, we find statistically significant and economically important program effects for both males and females. We also examine the representativeness of the Perry study. PMID:23255883

  5. Implementation of nanoscale circuits using dual metal gate engineered nanowire MOSFET with high-k dielectrics for low power applications

    NASA Astrophysics Data System (ADS)

    Charles Pravin, J.; Nirmal, D.; Prajoon, P.; Ajayan, J.

    2016-09-01

    This work covers the impact of dual metal gate engineered Junctionless MOSFET with various high-k dielectric in Nanoscale circuits for low power applications. Due to gate engineering in junctionless MOSFET, graded potential is obtained and results in higher electron velocity of about 31% for HfO2 than SiO2 in the channel region, which in turn improves the carrier transport efficiency. The simulation is done using sentaurus TCAD, ON current, OFF current, ION/IOFF ratio, DIBL, gain, transconductance and transconductance generation factor parameters are analysed. When using HfO2, DIBL shows a reduction of 61.5% over SiO2. The transconductance and transconductance generation factor shows an improvement of 44% and 35% respectively. The gain and output resistance also shows considerable improvement with high-k dielectrics. Using this device, inverter circuit is implemented with different high-k dielectric material and delay have been decreased by 4% with HfO2 when compared to SiO2. In addition, a significant reduction in power dissipation of the inverter circuit is obtained with high-k dielectric Dual Metal Surround Gate Junctionless Transistor than SiO2 based device. From the analysis, it is found that HfO2 will be a better alternative for the future nanoscale device.

  6. Theory and implementation of a very high throughput true random number generator in field programmable gate array.

    PubMed

    Wang, Yonggang; Hui, Cong; Liu, Chong; Xu, Chao

    2016-04-01

    The contribution of this paper is proposing a new entropy extraction mechanism based on sampling phase jitter in ring oscillators to make a high throughput true random number generator in a field programmable gate array (FPGA) practical. Starting from experimental observation and analysis of the entropy source in FPGA, a multi-phase sampling method is exploited to harvest the clock jitter with a maximum entropy and fast sampling speed. This parametrized design is implemented in a Xilinx Artix-7 FPGA, where the carry chains in the FPGA are explored to realize the precise phase shifting. The generator circuit is simple and resource-saving, so that multiple generation channels can run in parallel to scale the output throughput for specific applications. The prototype integrates 64 circuit units in the FPGA to provide a total output throughput of 7.68 Gbps, which meets the requirement of current high-speed quantum key distribution systems. The randomness evaluation, as well as its robustness to ambient temperature, confirms that the new method in a purely digital fashion can provide high-speed high-quality random bit sequences for a variety of embedded applications.

  7. Theory and implementation of a very high throughput true random number generator in field programmable gate array

    NASA Astrophysics Data System (ADS)

    Wang, Yonggang; Hui, Cong; Liu, Chong; Xu, Chao

    2016-04-01

    The contribution of this paper is proposing a new entropy extraction mechanism based on sampling phase jitter in ring oscillators to make a high throughput true random number generator in a field programmable gate array (FPGA) practical. Starting from experimental observation and analysis of the entropy source in FPGA, a multi-phase sampling method is exploited to harvest the clock jitter with a maximum entropy and fast sampling speed. This parametrized design is implemented in a Xilinx Artix-7 FPGA, where the carry chains in the FPGA are explored to realize the precise phase shifting. The generator circuit is simple and resource-saving, so that multiple generation channels can run in parallel to scale the output throughput for specific applications. The prototype integrates 64 circuit units in the FPGA to provide a total output throughput of 7.68 Gbps, which meets the requirement of current high-speed quantum key distribution systems. The randomness evaluation, as well as its robustness to ambient temperature, confirms that the new method in a purely digital fashion can provide high-speed high-quality random bit sequences for a variety of embedded applications.

  8. School-wide implementation of the elements of effective classroom instruction: Lessons from a high-performing, high-poverty urban school

    NASA Astrophysics Data System (ADS)

    Dyson, Hilarie

    2008-10-01

    The purpose of the study was to identify structures and systems implemented in a high-performing high-poverty urban school to promote high academic achievement among students of color. The researcher used a sociocultural theoretical framework to examine the influence of culture on the structures and systems that increased performance by African American and Hispanic students. Four research questions guided the study: (1) What are the trends and patterns of student performance among students of color? (2) What are the organizational structures and systems that are perceived to contribute to high student performance in high-poverty urban schools with high concentrations of students of color? (3) How are the organizational structures and systems implemented to support school-wide effective classroom instruction that promotes student learning? (4) How is the construct of race reflected in the school's structures and systems? Qualitative data were collected through interviews, observations, and artifact collection. A single case study method was employed and collected data were triangulated to capture and explore the rich details of the study. The study focused on a high-performing high-poverty urban elementary school located in southern California. The school population consisted of 99% students of color and 93% were economically disadvantaged. The school was selected for making significant and consistent growth in Academic Performance Index and Adequate Yearly Progress over a 3-year period. The school-wide structures and systems studied were (a) leadership, (b) school climate and culture, (c) standards-based instruction, (d) data-driven decision making, and (e) professional development. Four common themes emerged from the findings: (a) instructional leadership that focused on teaching and learning; (b) high expectations for all students; (c) school-wide focus on student achievement using standards, data, and culturally responsive teaching; and (d) positive

  9. Design and Implementation of High-Speed Input-Queued Switches Based on a Fair Scheduling Algorithm

    NASA Astrophysics Data System (ADS)

    Hu, Qingsheng; Zhao, Hua-An

    To increase both the capacity and the processing speed for input-queued (IQ) switches, we proposed a fair scalable scheduling architecture (FSSA). By employing FSSA comprised of several cascaded sub-schedulers, a large-scale high performance switches or routers can be realized without the capacity limitation of monolithic device. In this paper, we present a fair scheduling algorithm named FSSA_DI based on an improved FSSA where a distributed iteration scheme is employed, the scheduler performance can be improved and the processing time can be reduced as well. Simulation results show that FSSA_DI achieves better performance on average delay and throughput under heavy loads compared to other existing algorithms. Moreover, a practical 64 × 64 FSSA using FSSA_DI algorithm is implemented by four Xilinx Vertex-4 FPGAs. Measurement results show that the data rates of our solution can be up to 800Mbps and the tradeoff between performance and hardware complexity has been solved peacefully.

  10. A high precision method for mapping phase to amplitude in direct digital synthesis and its hardware implementation.

    PubMed

    Cao, Zhang; Song, Wei; Peng, Zhicong; Xu, Lijun

    2014-11-01

    There exist a number of algorithms to map the phase to amplitude in direct digital synthesis (DDS). For DDS with more than 14 output bits, the Coordinate Rotation Digital Computer (CORDIC) algorithm is well known for its high precision. Also, it is effective in solutions where there is the need of in-phase and quadrature components simultaneously because the algorithm calculates both. In this paper, a Taylor expansion based method was proposed to calculate both in-phase and quadrature at the same time. Numerical simulations for different data format, e.g., double and finite bits, were carried out in Matlab and Quartus, which were followed by the hardware implementation in Field Programmable Gate Array. The results demonstrated that the proposed method possessed higher precision and exhausted less logic elements than the CORDIC algorithm.

  11. Sensory processing within cockroach antenna enables rapid implementation of feedback control for high-speed running maneuvers.

    PubMed

    Mongeau, Jean-Michel; Sponberg, Simon N; Miller, John P; Full, Robert J

    2015-08-01

    Animals are remarkably stable during high-speed maneuvers. As the speed of locomotion increases, neural bandwidth and processing delays can limit the ability to achieve and maintain stable control. Processing the information of sensory stimuli into a control signal within the sensor itself could enable rapid implementation of whole-body feedback control during high-speed locomotion. Here, we show that processing in antennal afferents is sufficient to act as the control signal for a fast sensorimotor loop. American cockroaches Periplaneta americana use their antennae to mediate escape running by tracking vertical surfaces such as walls. A control theoretic model of wall following predicts that stable control is possible if the animal can compute wall position (P) and velocity, its derivative (D). Previous whole-nerve recordings from the antenna during simulated turning experiments demonstrated a population response consistent with P and D encoding, and suggested that the response was synchronized with the timing of a turn executed while wall following. Here, we record extracellularly from individual mechanoreceptors distributed along the antenna and show that these receptors encode D and have distinct latencies and filtering properties. The summed output of these receptors can be used as a control signal for rapid steering maneuvers. The D encoding within the antenna in addition to the temporal filtering properties and P dependence of the population of afferents support a sensory-encoding notion from control theory. Our findings support the notion that peripheral sensory processing can enable rapid implementation of whole-body feedback control during rapid running maneuvers.

  12. Next Generation Extractants for Cesium Separation from High-Level Waste: From Fundamental Concepts to Site Implementation

    SciTech Connect

    Moyer, Bruce A; Bazelaire, Eve; Bonnesen, Peter V; Custelcean, Radu; Delmau, Laetitia H; Ditto, Mary E; Engle, Nancy L; Gorbunova, Maryna G; Haverlock, Tamara J; Levitskaia, Taiana G; Bartsch, Richard A; Surowiec, Malgorzata A; Zhou, Hui

    2005-07-06

    This project unites expertise at Oak Ridge National Laboratory (ORNL) and Texas Tech University (TTU, Prof. Richard A. Bartsch) to answer fundamental questions addressing the problem of cesium removal from high-level tank waste. Efforts focus on novel solvent-extraction systems containing calixcrown extractants designed for enhanced cesium binding and release. Exciting results are being obtained in three areas: (1) a new lipophilic cesium extractant with a high solubility in the solvent; (2) new proton-ionizable calixcrowns that both strongly extract cesium and "switch off" when protonated; and (3) an improved solvent system that may be stripped with more than 100-fold greater efficiency. Scientific questions primarily concern how to more effectively reverse extraction, focusing on the use of amino groups and proton-ionizable groups to enable pH-switching. Synthesis is being performed at ORNL (amino calixcrowns) and TTU (proton-ionizable calixcrowns). At ORNL, the extraction behavior is being surveyed to assess the effectiveness of candidate solvent systems, and systematic distribution measurements are under way to obtain a thermodynamic understanding of partitioning and complexation equilibria. Crystal structures obtained at ORNL are revealing the structural details of cesium binding. The overall objective is a significant advance in the predictability and efficiency of cesium extraction from high-level waste in support of potential implementation at U. S. Department of Energy (USDOE) sites.

  13. Next Generation Extractants for Cesium Separation from High-Level Waste: From Fundamental Concepts to Site Implementation

    SciTech Connect

    Moyer, Bruce A.; Bazelaire, Eve; Bonnesen, Peter V.; Custelcean, Radu; Delmau, Laetitia H.; Ditto, Mary E.; Engle, Nancy L.; Gorbunova, Maryna G.; Haverlock, Tamara J.; Levitskaia, Tatiana G.; Bartsch, Richard A.; Surowiec, Malgorzata A.; Zhou, Hui

    2005-07-06

    This project unites expertise at Oak Ridge National Laboratory (ORNL) and Texas Tech University (TTU, Prof. Richard A. Bartsch) to answer fundamental questions addressing the problem of cesium removal from high-level tank waste. Efforts focus on novel solvent-extraction systems containing calixcrown extractants designed for enhanced cesium binding and release. Exciting results are being obtained in three areas: (1) a new lipophilic cesium extractant with a high solubility in the solvent; (2) new proton-ionizable calixcrowns that both strongly extract cesium and ''switch off'' when protonated; and (3) an improved solvent system that may be stripped with more than 100-fold greater efficiency. Scientific questions primarily concern how to more effectively reverse extraction, focusing on the use of amino groups and proton-ionizable groups to enable pH-switching. Synthesis is being performed at ORNL (amino calixcrowns) and TTU (proton-ionizable calixcrowns). At ORNL, the extraction behavior is being surveyed to assess the effectiveness of candidate solvent systems, and systematic distribution measurements are under way to obtain a thermodynamic understanding of partitioning and complexation equilibria. Crystal structures obtained at ORNL are revealing the structural details of cesium binding. The overall objective is a significant advance in the predictability and efficiency of cesium extraction from high-level waste in support of potential implementation at U. S. Department of Energy (USDOE) sites.

  14. DARTS: a low-cost high-performance FPGA implemented real-time control platform for adaptive optics

    NASA Astrophysics Data System (ADS)

    Goodsell, S. J.; Dipper, N. A.; Geng, D.; Myers, R. M.; Saunter, C. D.

    2005-08-01

    Durham University's Centre for Advanced Instrumentation (CfAI) are currently producing a generic high-performance low-cost real-time control system (RTCS) for adaptive optics (AO) based on Field Programmable Gate Array (FPGA) technology. This platform, labelled DARTS, 'Durham Adaptive optics Real Time System', will primarily be used as the controller for Durham's enhanced Rayleigh Technical Demonstrator (RTD) system. However, DARTS could be used as a low latency control system for existing AO instruments or could be used for future 'budget' AO Natural Guide Star (NGS) and/or Laser Guide Star (LGS) RTCS. DARTS uses an FPGA device to host an end-to-end modular real-time AO pipeline connected to a Wishbone control bus. The FPGA takes advantage of the pipeline's highly parallel computationally intensive tasks which usually are calculated in series by a system processor. DARTS hopes to increase the obtainable control loop frequency and reduce the computational latency of the RTD's RTCS. DARTS is capable of high bandwidth I/O due to the implementation of the serial Front Panel Data Port (sFPDP) industrial protocol. The hardware's I/O design is modular, allowing for the future connection of various WFSs and DMs via signal converters. Various communications architectures are suggested to allow non real-time configuration and visualisation data to flow between the wishbone control bus and a processing device, either externally or internally to the FPGA device. This paper reveals the current status of the project.

  15. High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound

    PubMed Central

    Schumann, Roman; Natov, Nikola S; Rocuts-Martinez, Klifford A; Finkelman, Matthew D; Phan, Tom V; Hegde, Sanjay R; Knapp, Robert M

    2016-01-01

    AIM To examine whether high-flow nasal oxygen (HFNO) availability influences the use of general anesthesia (GA) in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) and associated outcomes. METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras (era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era (era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively. RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3 (P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3 (P < 0.001) but not between eras 1 and 2 (P = 0.028) or 1 and 3 (P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation (P ≤ 0.007) as was the anesthesia-only time (P ≤ 0.001). CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. PMID:28058020

  16. Centrality dependence of high energy jets in p+Pb collisions at energies available at the CERN Large Hadron Collider

    SciTech Connect

    Bzdak, Adam; Skokov, Vladimir; Bathe, Stefan

    2016-04-08

    We investigate the recently measured centrality dependence of high energy jets in proton-lead collisions at the LHC. Here, we hypothesize that events with jets of very high energy (a few hundred GeV) are characterized by a suppressed number of soft particles, thus shifting these events into more peripheral bins. This naturally results in the suppression (enhancement) of the nuclear modification factor, RpA, in central (peripheral) collisions. Our calculations suggest that a moderate suppression of the order of 20%, for 103 GeV jets, can quantitatively reproduce the experimental data. Finally, we further extract the suppression factor as a function of jet energy and test our conjecture using available RpA data for various centralities.

  17. Implementation of PSF engineering in high-resolution 3D microscopy imaging with a LCoS (reflective) SLM

    NASA Astrophysics Data System (ADS)

    King, Sharon V.; Doblas, Ana; Patwary, Nurmohammed; Saavedra, Genaro; Martínez-Corral, Manuel; Preza, Chrysanthe

    2014-03-01

    Wavefront coding techniques are currently used to engineer unique point spread functions (PSFs) that enhance existing microscope modalities or create new ones. Previous work in this field demonstrated that simulated intensity PSFs encoded with a generalized cubic phase mask (GCPM) are invariant to spherical aberration or misfocus; dependent on parameter selection. Additional work demonstrated that simulated PSFs encoded with a squared cubic phase mask (SQUBIC) produce a depth invariant focal spot for application in confocal scanning microscopy. Implementation of PSF engineering theory with a liquid crystal on silicon (LCoS) spatial light modulator (SLM) enables validation of WFC phase mask designs and parameters by manipulating optical wavefront properties with a programmable diffractive element. To validate and investigate parameters of the GCPM and SQUBIC WFC masks, we implemented PSF engineering in an upright microscope modified with a dual camera port and a LCoS SLM. We present measured WFC PSFs and compare them to simulated PSFs through analysis of their effect on the microscope imaging system properties. Experimentally acquired PSFs show the same intensity distribution as simulation for the GCPM phase mask, the SQUBIC-mask and the well-known and characterized cubic-phase mask (CPM), first applied to high NA microscopy by Arnison et al.10, for extending depth of field. These measurements provide experimental validation of new WFC masks and demonstrate the use of the LCoS SLM as a WFC design tool. Although efficiency improvements are needed, this application of LCoS technology renders the microscope capable of switching among multiple WFC modes.

  18. Implementation literacy strategies on health technology theme Learning to enhance Indonesian Junior High School Student's Physics Literacy

    NASA Astrophysics Data System (ADS)

    Feranie, Selly; Efendi, Ridwan; Karim, Saeful; Sasmita, Dedi

    2016-08-01

    The PISA results for Indonesian Students are lowest among Asian countries in the past two successive results. Therefore various Innovations in science learning process and its effectiveness enhancing student's science literacy is needed to enrich middle school science teachers. Literacy strategies have been implemented on health technologies theme learning to enhance Indonesian Junior high school Student's Physics literacy in three different health technologies e.g. Lasik surgery that associated with application of Light and Optics concepts, Ultra Sonographer (USG) associated with application of Sound wave concepts and Work out with stationary bike and walking associated with application of motion concepts. Science learning process involves at least teacher instruction, student learning and a science curriculum. We design two main part of literacy strategies in each theme based learning. First part is Integrated Reading Writing Task (IRWT) is given to the students before learning process, the second part is scientific investigation learning process design packed in Problem Based Learning. The first part is to enhance student's science knowledge and reading comprehension and the second part is to enhance student's science competencies. We design a transformation from complexity of physics language to Middle school physics language and from an expensive and complex science investigation to a local material and simply hands on activities. In this paper, we provide briefly how literacy strategies proposed by previous works is redesigned and applied in classroom science learning. Data were analysed using t- test. The increasing value of mean scores in each learning design (with a significance level of p = 0.01) shows that the implementation of this literacy strategy revealed a significant increase in students’ physics literacy achievement. Addition analysis of Avarage normalized gain show that each learning design is in medium-g courses effectiveness category

  19. Sequential hydraulic tests for transient and highly permeable unconfined aquifer systems - model development and field-scale implementation

    NASA Astrophysics Data System (ADS)

    Ni, C.-F.; Huang, Y.-J.; Dong, J.-J.; Yeh, T.-C. J.

    2015-12-01

    The transient hydraulic tomography survey (THTS) is a conceptually improved technique that efficiently estimates detailed variations in aquifer parameters. Based on the concept of the THTS, we developed a geostatistical inverse model to characterize saturated hydraulic conductivity (K) and the specific yield (Sy) in transient and unconfined aquifer systems. In this study, a synthetic example was first used to assess the accuracy of the developed inverse model. Multiple random K and Sy realizations with different variances of natural logarithm of K (lnK) were generated and systematically compared to evaluate the effects of joint inversion on K estimations. The model was implemented in field-scale, cross-hole injection tests in a shallow and highly permeable unconfined aquifer near the middle reaches of the Wu River in central Taiwan. To assess the effect of constant head boundary conditions on the estimation results, two additional modeling domains were evaluated on the basis of the same field data from the injection tests. The results of the synthetic example showed that the proposed inverse model can effectively reproduce the predefined K patterns and magnitudes. However, slightly less detail was obtained for the Sy field based on the sampling data from sequential transient hydraulic stresses. The joint inversion by using transient head observations could slightly decrease the accuracy of K estimations. The model implementation for field-scale injection tests showed that the model can estimate K and Sy fields with detailed spatial variations. Estimation results showed a relatively homogeneous aquifer for the tested well field. Results based on the three modeling domains showed similar patterns and magnitudes of K and Sy near the well locations. These results indicated that the THTS is relatively insensitive to artificially drawn boundary conditions even under transient conditions.

  20. UWHS Climate Science: Uniting University Scientists and High School Teachers in the Development and Implementation of a Dual-Credit STEM-Focused Curriculum

    NASA Astrophysics Data System (ADS)

    Bertram, M. A.; Thompson, L.; Ackerman, T. P.

    2012-12-01

    The University of Washington is adapting a popular UW Atmospheric Sciences course on Climate and Climate Change for the high school environment. In the process, a STEM-focused teaching and learning community has formed. With the support of NASA Global Climate Change Education 20 teachers have participated in an evolving professional development program that brings those actively engaged in research together with high school teachers passionate about bringing a formal climate science course into the high school. Over a period of several months participating teachers work through the UW course homework and delve deeply into specific subject areas. Then, during a week-long summer institute, scientists bring their particular expertise (e.g. radiation, modeling) to the high school teachers through lectures or labs. Together they identify existing lectures, textbook material and peer-reviewed resources and labs available through the internet that can be used to effectively teach the UW material to the high school students. Through this process the scientists learn how to develop teaching materials around their area of expertise, teachers engage deeply in the subject matter, and both the university and high school teachers are armed with the tools to effectively teach a STEM-focused introductory course in climate science. To date 12 new hands-on modules have been completed or are under development, exploring ice-cores, isotopes, historical temperature trends, energy balance, climate models, and more. Two modules have been tested in the classroom and are ready for peer-review through well-respected national resources such as CLEAN or the National Earth Science Teachers Association; three others are complete and will be implemented in a high school classroom this year, and the remainder under various stages of development. The UWHS ATMS 211 course was piloted in two APES (Advanced Placement Environmental Science classrooms) in Washington State in 2011/2012. The high school

  1. Free-choice and no-choice high-fat diets affect striatal dopamine D2/3 receptor availability, caloric intake, and adiposity.

    PubMed

    van de Giessen, Elsmarieke; la Fleur, Susanne E; de Bruin, Kora; van den Brink, Wim; Booij, Jan

    2012-08-01

    Different types of high-fat (HF) diets are used to study diet-induced obesity (DIO) in rodents and this has led to different phenotypes. This study assesses whether different HF diets differentially affect striatal dopamine D(2/3) receptor (DRD(2/3)) availability, as decreased striatal DRD(2/3) availability has been implicated in obesity in relation to reward deficiency for food. Thirty rats were randomized to either a free-choice HF diet (HF-choice), a premixed HF diet (HF-no-choice), or a standard chow diet for 28 days. Striatal DRD(2/3) was measured using (123)I-IBZM storage phosphor imaging at day 29. DRD(2/3) availability was significantly decreased in the dorsal striatum in the HF-choice rats compared to chow rats, but not in HF-no-choice rats. Additionally, caloric intake of the HF-choice rats was significantly higher than that of HF-no-choice rats and serum leptin and percentage abdominal fat store weight of total body weight were significantly higher in the HF-choice rats compared to chow rats. These preliminary results suggest that the choice element in HF diets, which is possibly related to the motivational aspects of eating, leads to overconsumption and to a distinct state of obesity. These results are relevant for future studies on DIO when considering choice of diet type.

  2. Effect of phytase application during high gravity (HG) maize mashes preparation on the availability of starch and yield of the ethanol fermentation process.

    PubMed

    Mikulski, D; Kłosowski, G; Rolbiecka, A

    2014-10-01

    Phytic acid present in raw materials used in distilling industry can form complexes with starch and divalent cations and thus limit their biological availability. The influence of the enzymatic hydrolysis of phytate complexes on starch availability during the alcoholic fermentation process using high gravity (HG) maize mashes was analyzed. Indicators of the alcoholic fermentation as well as the fermentation activity of Saccharomyces cerevisiae D-2 strain were statistically evaluated. Phytate hydrolysis improved the course of the alcoholic fermentation of HG maize mashes. The final ethanol concentration in the media supplemented with phytase applied either before or after the starch hydrolysis increased by 1.0 and 0.6 % v/v, respectively, as compared to the control experiments. This increase was correlated with an elevated fermentation yield that was higher by 5.5 and 2.0 L EtOH/100 kg of starch, respectively. Phytate hydrolysis resulted also in a statistically significant increase in the initial concentration of fermenting sugars by 14.9 mg/mL of mash, on average, which was a consequence of a better availability of starch for enzymatic hydrolysis. The application of phytase increased the attenuation of HG media fermentation thus improving the economical aspect of the ethanol fermentation process.

  3. Niche shifts and energetic condition of songbirds in response to phenology of food-resource availability in a high-elevation sagebrush ecosystem

    USGS Publications Warehouse

    Cutting, Kyle A.; Anderson, Michelle L.; Beever, Erik; Schroff, Sean; Korb, Nathan; Klaphake, Eric; McWilliams, Scott R.

    2016-01-01

    Seasonal fluctuations in food availability can affect diets of consumers, which in turn may influence the physiological state of individuals and shape intra- and inter-specific patterns of resource use. High-elevation ecosystems often exhibit a pronounced seasonal “pulse” in productivity, although few studies document how resource use and energetic condition by avian consumers change in relation to food-resource availability in these ecosystems. We tested the hypothesis that seasonal increases (pulses) in food resources in high-elevation sagebrush ecosystems result in 2 changes after the pulse, relative to the before-pulse period: (1) reduced diet breadth of, and overlap between, 2 sympatric sparrow species; and (2) enhanced energetic condition in both species. We tracked breeding-season diets using stable isotopes and energetic condition using plasma metabolites of Brewer's Sparrows (Spizella breweri), Vesper Sparrows (Pooecetes gramineus), and their food resources during 2011, and of only Brewer's Sparrows and their food resources during 2013. We quantify diet breadth and overlap between both species, along with coincident physiological consequences of temporal changes in resource use. After invertebrate biomass increased following periods of rainfall in 2011, dietary breadth decreased by 35% in Brewer's Sparrows and by 48% in Vesper Sparrows, while dietary overlap decreased by 88%. Energetic condition of both species increased when dietary overlap was lower and diet breadth decreased, after the rapid rise of food-resource availability. However, energetic condition of Brewer's Sparrows remained constant in 2013, a year with low precipitation and lack of a strong pulse in food resources, even though the species' dietary breadth again decreased that year. Our results indicate that diet breadth and overlap in these sparrow species inhabiting sagebrush ecosystems generally varied as predicted in relation to intra- and interannual changes in food resources, and

  4. Long-term high-temperature and pH stability assessment of modern commercially available stationary phases by using retention factor analysis.

    PubMed

    Haun, Jakob; Oeste, Katja; Teutenberg, Thorsten; Schmidt, Torsten C

    2012-11-09

    High-temperature liquid chromatography provides several advantages concerning HPLC method development and is needed to realize special hyphenation techniques. However, hardware limitations and stationary phase degradation can prevent the successful application of this technique. Therefore, column stability is of major importance. The presented study contains results of long-term high-temperature stability tests for eight modern commercially available HPLC stationary phases. Six of them were silica-based reversed-phase C18 columns tested according to an earlier reported procedure (Teutenberg, 2009 [12]). On the basis of the extended data set that covers a wide range of column technologies, a comparative approach using retention factor analysis was evaluated in order to categorize the columns according to their long-term high-temperature stability at 150 °C and changing pH value. This approach offers a more objective alternative to conventional listings in which temperature maxima are compared for columns tested under different conditions. Additionally, customized tests are presented for one promising polymer-based C18 stationary phase and an amide column for hydrophilic interaction liquid chromatography.

  5. How does implementation of inquiry-based science instruction in a high-stakes testing environment affect fifth-grade student science achievement?

    NASA Astrophysics Data System (ADS)

    Kessner, Micheal J.

    The purpose of this study was to assess the affects of hands-on, inquiry-based instruction on student science achievement in a high-stakes testing environment. Hands-on, inquiry-based science has become a popular way of teaching science because it is inviting and interesting for students. However, the question remains: Does implementation of inquiry-based science instruction in a high-stakes testing environment affect fifth-grade student science achievement? A quasi-experimental design employing quantitative and qualitative methods was used. The quantitative portion consisted of data collected from Student Surveys and individual science achievement scores for fifth-grade students at three participating schools in a large, suburban school district. The qualitative portion consisted of data collected using a Science Kit Usage Checklist, an open ended Teacher Survey of 5 fifth-grade science teachers, and Teacher Interviews for 3 fifth-grade science teachers. Descriptive analysis was utilized, and emerging codes and themes were identified for teacher education, science kit training, and understanding and implementation of science kits. Data and methods triangulation were employed (Berg, 2006; Patten, 2005) All data were utilized to determine if implementation of Science Kits impacted science achievement scores in a high stakes testing environment. Results indicated a general improvement of students meeting mastery of the fifth-grade science state assessment when kits were implemented. Teacher fidelity and high implementation were validated with Student and Teacher Surveys. Themes emerged involving training, time, student response, impact on instruction, impact on achievement scores, instructional organization, and instructional changes in future implementation. District supported training and materials led to teacher and student enjoyment of science kits, which led to implementation. Implementation then led to higher fifth-grade science achievement scores.

  6. The implementation of anaerobic digestion of food waste in a highly populated urban area: an LCA evaluation.

    PubMed

    Grosso, Mario; Nava, Chiara; Testori, Roberta; Rigamonti, Lucia; Viganò, Federico

    2012-09-01

    While source separation of waste packaging materials for recycling is well established in several metropolitan areas, the collection of food waste from the households is less widespread because of its more difficult implementation. Source segregation of food waste in densely populated areas is raising new interest, as the availability of biogas following its anaerobic digestion (AD) paves the road to a number of possibilities, from electric energy production to its upgrading to biomethane and subsequent feeding in to the natural gas network or in vehicles as a fuel. The study addresses this waste management option by analysing a real metropolitan situation where food waste currently ends up mixed with the residual waste in a waste-to-energy plant (WTE). We assume to establish a new collection scheme for household food waste, followed by its treatment in a new AD and post-composting facility. A comparative life cycle assessment was carried out, where possible synergies between the existing WTE plant and the new one were evaluated. All new scenarios based on AD attained similar or better results compared with the reference scenario for almost all of the impact indicators. The most robust indication is related to global warming potential, with a potential improvement of up to 37%. Finally, a sensitivity analysis was carried out to assess the effect of the variation of the most relevant parameters. Results have proven to be very sensible to the hypothesis on the type of substituted electric energy. All the other examined sensitivities resulted in variations well below 10%.

  7. High School English Teachers' Experiences in the Implementation of the Elements of Effective Adolescent Literacy Instruction Using the "SpringBoard" Curriculum

    ERIC Educational Resources Information Center

    Hebert, Anita

    2013-01-01

    This qualitative case study used focus groups to investigate the experiences of 11 high school English teachers in their implementation of the effective practices of adolescent literacy instruction while using the "SpringBoard" curriculum by College Board. Focus groups were held in three comparable suburban high schools that utilized…

  8. Five Years of Enhanced "HSTW" in Texas: Raising Achievement and Preparing Students for College and Careers through Dedicated Implementation of the "HSTW" Key Practices. High Schools That Work

    ERIC Educational Resources Information Center

    Southern Regional Education Board (SREB), 2011

    2011-01-01

    The Texas Education Agency (TEA) and the Southern Regional Education Board (SREB) joined hands in 2005 to enhance dramatically implementation of the "High Schools That Work" ("HSTW") improvement design in the state. Between 2005 and 2010, nearly 50 high schools in five cohorts joined the Texas Enhanced "HSTW" Network…

  9. The Effect of the Involvement within Career Academies by Elective Participation of Eleventh and Twelfth Grade High School Students during the Implementation Year

    ERIC Educational Resources Information Center

    Johnston, Nancy A.

    2010-01-01

    The purpose of this study was to determine the effect of elective participation in one of three implementation year Career Academies, Education, Entrepreneurship, or Finance, on upper-class high school academic grades, Grade Point Average, and school academy participation measures. Significance of the junior and senior year of high school, the…

  10. Measles prevention in adolescents: lessons learnt from implementing a high school catch-up vaccination programme in New South Wales, Australia, 2014–2015

    PubMed Central

    Seale, Holly; Sheppeard, Vicky; Campbell-Lloyd, Sue

    2016-01-01

    Introduction In response to a significant increase of measles cases and a high percentage of unvaccinated adolescents in New South Wales, Australia, a measles high school catch-up vaccination programme was implemented between August and December 2014. This study aimed to explore the factors affecting school-based supplementary immunization activities (SIAs) and to inform future SIA and routine school-based vaccination programme implementation and service provision. Methods Focus group analysis was conducted among public health unit (PHU) staff responsible for implementing the SIA catch-up programme. Key areas discussed were pre-programme planning, implementation, resources, consent materials, media activity and future directions for school vaccination programme delivery. Sessions were audio recorded, transcribed verbatim and reviewed. Thematic analysis was conducted to identify the major themes. Results Two independent focus groups with 32 participants were conducted in January 2015. Barriers to the SIA implementation included lead time, consent processes, interagency collaboration, access to the targeted cohort and the impact of introducing a SIA to an already demanding curriculum and school programme immunization schedule. A positive PHU school coordinator rapport and experience of PHU staff facilitated the implementation. Consideration of different approaches for pre-clinic vaccination status checks, student involvement in the vaccination decision, online consent, workforce sharing between health districts and effective programme planning time were identified for improving future SIA implementation. Conclusion Although many barriers to school programme implementation have been identified in this study, with adequate resourcing and lead time, SIAs implemented via a routine school vaccination programme are an appropriate model to target adolescents. PMID:27757258

  11. Administrator Strategies that Support High Fidelity Implementation of the Pyramid Model for Promoting Social-Emotional Competence & Addressing Challenging Behavior

    ERIC Educational Resources Information Center

    Mincic, Melissa; Smith, Barbara J.; Strain, Phil

    2009-01-01

    Implementing the Pyramid Model with fidelity and achieving positive outcomes for children and their families requires that administrators understand their roles in the implementation process. Every administrative decision impacts program quality and sustainability. This Policy Brief underscores the importance of facilitative administrative…

  12. Biochar from sugarcane filtercake reduces soil CO2 emissions relative to raw residue and improves water retention and nutrient availability in a highly-weathered tropical soil.

    PubMed

    Eykelbosh, Angela Joy; Johnson, Mark S; Santos de Queiroz, Edmar; Dalmagro, Higo José; Guimarães Couto, Eduardo

    2014-01-01

    In Brazil, the degradation of nutrient-poor Ferralsols limits productivity and drives agricultural expansion into pristine areas. However, returning agricultural residues to the soil in a stabilized form may offer opportunities for maintaining or improving soil quality, even under conditions that typically promote carbon loss. We examined the use of biochar made from filtercake (a byproduct of sugarcane processing) on the physicochemical properties of a cultivated tropical soil. Filtercake was pyrolyzed at 575°C for 3 h yielding a biochar with increased surface area and porosity compared to the raw filtercake. Filtercake biochar was primarily composed of aromatic carbon, with some residual cellulose and hemicellulose. In a three-week laboratory incubation, CO2 effluxes from a highly weathered Ferralsol soil amended with 5% biochar (dry weight, d.w.) were roughly four-fold higher than the soil-only control, but 23-fold lower than CO2 effluxes from soil amended with 5% (d.w.) raw filtercake. We also applied vinasse, a carbon-rich liquid waste from bioethanol production typically utilized as a fertilizer on sugarcane soils, to filtercake- and biochar-amended soils. Total CO2 efflux from the biochar-amended soil in response to vinasse application was only 5% of the efflux when vinasse was applied to soil amended with raw filtercake. Furthermore, mixtures of 5 or 10% biochar (d.w.) in this highly weathered tropical soil significantly increased water retention within the plant-available range and also improved nutrient availability. Accordingly, application of sugarcane filtercake as biochar, with or without vinasse application, may better satisfy soil management objectives than filtercake applied to soils in its raw form, and may help to build soil carbon stocks in sugarcane-cultivating regions.

  13. Biochar from Sugarcane Filtercake Reduces Soil CO2 Emissions Relative to Raw Residue and Improves Water Retention and Nutrient Availability in a Highly-Weathered Tropical Soil

    PubMed Central

    Eykelbosh, Angela Joy; Johnson, Mark S.; Santos de Queiroz, Edmar; Dalmagro, Higo José; Guimarães Couto, Eduardo

    2014-01-01

    In Brazil, the degradation of nutrient-poor Ferralsols limits productivity and drives agricultural expansion into pristine areas. However, returning agricultural residues to the soil in a stabilized form may offer opportunities for maintaining or improving soil quality, even under conditions that typically promote carbon loss. We examined the use of biochar made from filtercake (a byproduct of sugarcane processing) on the physicochemical properties of a cultivated tropical soil. Filtercake was pyrolyzed at 575°C for 3 h yielding a biochar with increased surface area and porosity compared to the raw filtercake. Filtercake biochar was primarily composed of aromatic carbon, with some residual cellulose and hemicellulose. In a three-week laboratory incubation, CO2 effluxes from a highly weathered Ferralsol soil amended with 5% biochar (dry weight, d.w.) were roughly four-fold higher than the soil-only control, but 23-fold lower than CO2 effluxes from soil amended with 5% (d.w.) raw filtercake. We also applied vinasse, a carbon-rich liquid waste from bioethanol production typically utilized as a fertilizer on sugarcane soils, to filtercake- and biochar-amended soils. Total CO2 efflux from the biochar-amended soil in response to vinasse application was only 5% of the efflux when vinasse was applied to soil amended with raw filtercake. Furthermore, mixtures of 5 or 10% biochar (d.w.) in this highly weathered tropical soil significantly increased water retention within the plant-available range and also improved nutrient availability. Accordingly, application of sugarcane filtercake as biochar, with or without vinasse application, may better satisfy soil management objectives than filtercake applied to soils in its raw form, and may help to build soil carbon stocks in sugarcane-cultivating regions. PMID:24897522

  14. School and district wellness councils and availability of low-nutrient, energy-dense vending fare in Minnesota middle and high schools.

    PubMed

    Kubik, Martha Y; Lytle, Leslie A; Farbakhsh, Kian

    2011-01-01

    The Child Nutrition and WIC Reauthorization Act of 2004 required school districts participating in the federal school meals program to establish by the start of the 2006-2007 school year policies that included nutrition guidelines for all foods sold on school campus during the school day and policy development involving key stakeholders. For many schools, policy development was done by wellness councils. This study examined the association between having a wellness council and availability of low-nutrient, energy-dense foods/beverages in school vending machines following enactment of the federal legislation. In 2006-2007, Minnesota middle (n=35) and high (n=54) school principals reported whether their school and district had a wellness council. Trained research staff observed foods/beverages in vending machines accessible to students. Low-nutrient, energy-dense foods/beverages (snacks >3 g fat or >200 calories/serving, and soda, fruit/sport drinks and reduced-fat/whole milk) were grouped into seven categories (eg, high-fat baked goods) and a food score was calculated. Higher scores indicated more low-nutrient, energy-dense vending fare. Multivariate linear regression, adjusted for school characteristics, was used to examine associations between scores and a three-category council variable (district-only; district and school; no council). Among schools, 53% had district-only councils, 38% district and school councils, and 9% had no council. Schools with both a district and school council had a significantly lower mean food score than schools without councils (P=0.03). The potential of wellness councils to impact availability of low-nutrient, energy-dense vending fare is promising. There may be an added benefit to having both a school and district council.

  15. School and District Wellness Councils and Availability of Low-Nutrient, Energy-Dense Vending Fare in Minnesota Middle and High Schools

    PubMed Central

    Kubik, Martha Y.; Lytle, Leslie A.; Farbakhsh, Kian

    2011-01-01

    The Child Nutrition and WIC Reauthorization Act of 2004 required school districts participating in the federal school meals program to establish by the start of the 2006–2007 school year policies that included nutrition guidelines for all foods sold on school campus during the school day and policy development involving key stakeholders. For many schools, policy development was done by wellness councils. This study examined the association between having a wellness council and availability of low-nutrient, energy-dense foods/beverages in school vending machines following enactment of the federal legislation. In 2006–2007, Minnesota middle (n=35) and high (n=54) school principals reported whether their school and district had a wellness council. Trained research staff observed foods/beverages in vending machines accessible to students. Low-nutrient, energy-dense foods/beverages (snacks >3 g fat or >200 calories/serving, and soda, fruit/sport drinks and reduced-fat/whole milk) were grouped into seven categories (eg, high-fat baked goods) and a food score was calculated. Higher scores indicated more low-nutrient, energy-dense vending fare. Multivariate linear regression, adjusted for school characteristics, was used to examine associations between scores and a three-category council variable (district-only; district and school; no council). Among schools, 53% had district-only councils, 38% district and school councils, and 9% had no council. Schools with both a district and school council had a significantly lower mean food score than schools without councils (P=0.03). The potential of wellness councils to impact availability of low-nutrient, energy-dense vending fare is promising. There may be an added benefit to having both a school and district council. PMID:21185978

  16. How Integrated Management Strategies Promote Protein Quality of Cotton Embryos: High Levels of Soil Available N, N Assimilation and Protein Accumulation Rate

    PubMed Central

    Yang, HongKun; Meng, YaLi; Chen, BingLin; Zhang, XingYue; Wang, YouHua; Zhao, WenQing; Zhou, ZhiGuo

    2016-01-01

    Cottonseed is widely used as a source of ruminant feed and for industrial purposes. Therefore, there is a tremendous need to improve the nutritional value of cotton embryos. In this study, a conventional management (CM) and two integrated cotton management strategies (IMS1, IMS2) were performed at two soil fertility levels to study the relationships among soil N, N assimilation, embryonic protein accumulation and protein quality. The levels of proteins, essential amino acids, and semi-essential amino acids, especially those of glutamate, lysine, and methionine, were higher in IMS1 and IMS2 embryos than in CM embryos. These changes were significantly positively correlated with the soil-available N content, glutamine synthetase activity and peak value of protein accumulation rate and were negatively correlated with the free amino acid level. These results illustrated that integrated management strategies, especially the rates and timing of N application, raise the level of soil available N, which is beneficial for N assimilation in developing cotton embryos. The protein content was limited by the rate of protein accumulation rather than by the free amino acid content. The combination of target yield fertilization, a growth-driven N application schedule, a high plant density and the seedling raising with bio-organic fertilizer can substantially improve protein quality in cotton embryos, especially at a soil with low soil organic matter and total nitrogen. PMID:27532007

  17. How Integrated Management Strategies Promote Protein Quality of Cotton Embryos: High Levels of Soil Available N, N Assimilation and Protein Accumulation Rate.

    PubMed

    Yang, HongKun; Meng, YaLi; Chen, BingLin; Zhang, XingYue; Wang, YouHua; Zhao, WenQing; Zhou, ZhiGuo

    2016-01-01

    Cottonseed is widely used as a source of ruminant feed and for industrial purposes. Therefore, there is a tremendous need to improve the nutritional value of cotton embryos. In this study, a conventional management (CM) and two integrated cotton management strategies (IMS1, IMS2) were performed at two soil fertility levels to study the relationships among soil N, N assimilation, embryonic protein accumulation and protein quality. The levels of proteins, essential amino acids, and semi-essential amino acids, especially those of glutamate, lysine, and methionine, were higher in IMS1 and IMS2 embryos than in CM embryos. These changes were significantly positively correlated with the soil-available N content, glutamine synthetase activity and peak value of protein accumulation rate and were negatively correlated with the free amino acid level. These results illustrated that integrated management strategies, especially the rates and timing of N application, raise the level of soil available N, which is beneficial for N assimilation in developing cotton embryos. The protein content was limited by the rate of protein accumulation rather than by the free amino acid content. The combination of target yield fertilization, a growth-driven N application schedule, a high plant density and the seedling raising with bio-organic fertilizer can substantially improve protein quality in cotton embryos, especially at a soil with low soil organic matter and total nitrogen.

  18. Comparison of performance of object-based image analysis techniques available in open source software (Spring and Orfeo Toolbox/Monteverdi) considering very high spatial resolution data

    NASA Astrophysics Data System (ADS)

    Teodoro, Ana C.; Araujo, Ricardo

    2016-01-01

    The use of unmanned aerial vehicles (UAVs) for remote sensing applications is becoming more frequent. However, this type of information can result in several software problems related to the huge amount of data available. Object-based image analysis (OBIA) has proven to be superior to pixel-based analysis for very high-resolution images. The main objective of this work was to explore the potentialities of the OBIA methods available in two different open source software applications, Spring and OTB/Monteverdi, in order to generate an urban land cover map. An orthomosaic derived from UAVs was considered, 10 different regions of interest were selected, and two different approaches were followed. The first one (Spring) uses the region growing segmentation algorithm followed by the Bhattacharya classifier. The second approach (OTB/Monteverdi) uses the mean shift segmentation algorithm followed by the support vector machine (SVM) classifier. Two strategies were followed: four classes were considered using Spring and thereafter seven classes were considered for OTB/Monteverdi. The SVM classifier produces slightly better results and presents a shorter processing time. However, the poor spectral resolution of the data (only RGB bands) is an important factor that limits the performance of the classifiers applied.

  19. Using available information to assess the potential effects of climate change on vegetation in the High Arctic: north Billjefjorden, central Spitsbergen (Svalbard).

    PubMed

    Klimešová, Jitka; Prach, Karel; Bernardová, Alexandra

    2012-07-01

    We review the available data that can be used to assess the potential impact of climate change on vegetation, and we use central Spitsbergen, Svalbard, as a model location for the High Arctic. We used two sources of information: recent and short-term historical records, which enable assessment on scales of particular plant communities and the landscape over a period of decades, and palynological and macrofossil analyses, which enable assessment on time scales of hundreds and thousands of years and on the spatial scale of the landscape. Both of these substitutes for standardized monitoring revealed stability of vegetation, which is probably attributable to the harsh conditions and the distance of the area from sources of diaspores of potential new incomers. The only evident recent vegetation changes related to climate change are associated with succession after glacial retreats. By establishing a network of permanent plots, researchers will be able to monitor immigration of new species from diversity 'hot spots' and from an abandoned settlement nearby. This will greatly enhance our ability to understand the effects of climate change on vegetation in the High Arctic.

  20. Free availability of high-energy foods led to energy over-ingestion and protein under-ingestion in choice-fed broilers.

    PubMed

    Catanese, Francisco; Rodriguez Ganduglia, Héctor; Villalba, Juan J; Distel, Roberto A

    2015-12-01

    The objective of this study was to compare energy and protein content of the diet selected by choice-fed broilers with that of broilers fed a balanced diet. One hundred and eighty 1-day-old male broilers were randomly assigned in groups of 10 to one of three experimental treatments (n = 6). Control broilers were fed a standard balanced diet, whereas choice-fed broilers were fed three foods which were more concentrated (Choice C+ treatment) or less concentrated (Choice C- treatment) in protein, carbohydrate or fat. We evaluated food intake behavior, nutrient intake, and performance parameters of broilers from 2 to 7 weeks of age. Choice C+ broilers showed enhanced preference for the high-fat food, which led to higher energy intake and lower protein intake than those of control broilers at 2 to 4 weeks of age. Body weight, weight gain and feed conversion efficiency were negatively affected by diet selection of Choice C+ broilers. Choice C- broilers selected a balanced diet, and showed performance parameters similar to those of control broilers. Our results supported the hypothesis that free availability of high-energy foods bias ingestive behavior of choice-fed broilers toward selecting a diet with higher energy and lower protein than needed for normal growth.