NASA Astrophysics Data System (ADS)
Cohen, K. K.; Klara, S. M.; Srivastava, R. D.
2004-12-01
The U.S. Department of Energy's (U.S. DOE's) Carbon Sequestration Program is developing state-of-the-science technologies for measurement, mitigation, and verification (MM&V) in field operations of geologic sequestration. MM&V of geologic carbon sequestration operations will play an integral role in the pre-injection, injection, and post-injection phases of carbon capture and storage projects to reduce anthropogenic greenhouse gas emissions. Effective MM&V is critical to the success of CO2 storage projects and will be used by operators, regulators, and stakeholders to ensure safe and permanent storage of CO2. In the U.S. DOE's Program, Carbon sequestration MM&V has numerous instrumental roles: Measurement of a site's characteristics and capability for sequestration; Monitoring of the site to ensure the storage integrity; Verification that the CO2 is safely stored; and Protection of ecosystems. Other drivers for MM&V technology development include cost-effectiveness, measurement precision, and frequency of measurements required. As sequestration operations are implemented in the future, it is anticipated that measurements over long time periods and at different scales will be required; this will present a significant challenge. MM&V sequestration technologies generally utilize one of the following approaches: below ground measurements; surface/near-surface measurements; aerial and satellite imagery; and modeling/simulations. Advanced subsurface geophysical technologies will play a primary role for MM&V. It is likely that successful MM&V programs will incorporate multiple technologies including but not limited to: reservoir modeling and simulations; geophysical techniques (a wide variety of seismic methods, microgravity, electrical, and electromagnetic techniques); subsurface fluid movement monitoring methods such as injection of tracers, borehole and wellhead pressure sensors, and tiltmeters; surface/near surface methods such as soil gas monitoring and infrared sensors and; aerial and satellite imagery. This abstract will describe results, similarities, and contrasts for funded studies from the U.S. DOE's Carbon Sequestration Program including examples from the Sleipner North Sea Project, the Canadian Weyburn Field/Dakota Gasification Plant Project, the Frio Formation Texas Project, and Yolo County Bioreactor Landfill Project. The abstract will also address the following: How are the terms ``measurement,'' ``mitigation''and ``verification'' defined in the Program? What is the U.S. DOE's Carbon Sequestration Program Roadmap and what are the Roadmap goals for MM&V? What is the current status of MM&V technologies?
Li, Yueyue; Wang, Yang; Hu, John; Xiao, Long; Tan, Guanlin; Lan, Pingxiu; Liu, Yong; Li, Fan
2017-01-31
Tomato mottle mosaic virus (ToMMV) is a recently identified species in the genus Tobamovirus and was first reported from a greenhouse tomato sample collected in Mexico in 2013. In August 2013, ToMMV was detected on peppers (Capsicum spp.) in China. However, little is known about the molecular and biological characteristics of ToMMV. Reverse transcription-polymerase chain reaction (RT-PCR) and rapid identification of cDNA ends (RACE) were carried out to obtain the complete genomic sequences of ToMMV. Sap transmission was used to test the host range and pathogenicity of ToMMV. The full-length genomes of two ToMMV isolates infecting peppers in Yunnan Province and Tibet Autonomous Region of China were determined and analyzed. The complete genomic sequences of both ToMMV isolates consisted of 6399 nucleotides and contained four open reading frames (ORFs) encoding 126, 183, 30 and 18 kDa proteins from the 5' to 3' end, respectively. Overall similarities of the ToMMV genome sequence to those of the other tobamoviruses available in GenBank ranged from 49.6% to 84.3%. Phylogenetic analyses of the sequences of full-genome nucleotide and the amino acids of its four proteins confirmed that ToMMV was most closely related to Tomato mosaic virus (ToMV). According to the genetic structure, host of origin and phylogenetic relationships, the available 32 tobamoviruses could be divided into at least eight subgroups based on the host plant family they infect: Solanaceae-, Brassicaceae-, Cactaceae-, Apocynaceae-, Cucurbitaceae-, Malvaceae-, Leguminosae-, and Passifloraceae-infecting subgroups. The detection of ToMMV on some solanaceous, cucurbitaceous, brassicaceous and leguminous plants in Yunnan Province and other few parts of China revealed ToMMV only occurred on peppers so far. However, the host range test results showed ToMMV could infect most of the tested solanaceous and cruciferous plants, and had a high affinity for the solanaceous plants. The complete nucleotide sequences of two Chinese ToMMV isolates from naturally infected peppers were verified. The tobamoviruses were divided into at least eight subgroups, with ToMMV belonging to the subgroup that infected plants in the Solanaceae. In China, ToMMV only occurred on peppers in the fields till now. ToMMV could infect the plants in family Solanaceae and Cucurbitaceae by sap transmission.
Higashi, C H V; Bressan, A
2013-10-01
We examined the population dynamics of the corn planthopper Peregrinus maidis (Ashmead) (Hemiptera: Delphacidae) throughout a cycle of corn (Zea mays L.) production on plants with or without symptoms of maize mosaic virus (MMV) (Rhabdoviridae: Nucleorhabdovirus) infection. Our results indicate that the timing of MMV plant infection greatly influenced the planthopper's host plant colonization patterns. Corn plants that expressed symptoms of MMV infection early in the crop cycle (28 d after planting) harbored, on average, 40 and 48% fewer planthoppers than plants that expressed symptoms of MMV infection later in the crop cycle (49 d after planting) and asymptomatic plants, respectively. We also observed a change in the number of brachypterous (short-wing type) and macropterous (long-wing type) winged forms produced; plants expressing early symptoms of MMV infection harbored, on average, 41 and 47% more of the brachypterous form than plants with late infections of MMV and plants with no symptoms of MMV, respectively. Furthermore, we determined the rates of MMV-infected planthoppers relative to their wing morphology (macropterous or brachypterous) and gender. MMV infection was 5 and 12% higher in females than in males in field and greenhouse experiments, respectively; however, these differences were not significantly different. This research provides evidence that MMV similarly infects P. maidis planthoppers regardless of the gender and wing morphotype. These results also suggest that the timing of symptom development greatly affects the population dynamics of the planthopper vector, and likely has important consequences for the dynamics of the disease in the field.
Kunita, Satoshi; Chaya, Miyuki; Hagiwara, Kozue; Ishida, Tomoko; Takakura, Akira; Sugimoto, Tatsuya; Iseki, Hiroyoshi; Fuke, Kumiko; Sugiyama, Fumihiro; Yagami, Ken-ichi
2006-04-01
Nucleotide sequences of mouse parvovirus (MPV) isolate, named MPV/UT, and mouse minute virus (MMV) were analyzed and used for expressing recombinant proteins in E. coli. ELISA tests using recombinant major capsid protein (rVP2) and recombinant major non-structural protein (rNS1) as antigens were developed and their performance in serologic detection of rodent parvovirus infection was assessed. MPV-rVP2 and MMV-rVP2 ELISAs reacted specifically with anti-MPV and anti-MMV mouse sera, respectively. MMV-rNS1 antigen had a wide reaction range with antisera to rodent parvoviruses including MPV, MMV, Kilham rat virus (KRV) and H-1 virus. All mice oronasally infected with MPV were seropositive at 4 weeks post-infection in screening by ELISAs using MPV-rVP2 and MMV-rNS1 antigens, but were negative by conventional ELISA using whole MMV antigen. A contact transmission experiment revealed that transmission of MPV occurred up to 4 weeks post-infection, and all cage mates were seropositive in screening with MPV-rVP2 and MMV-rNS1 ELISAs. These results indicate that MPV-rVP2 and MMV-rVP2 are specific ELISA antigens which distinguish between MPV and MVM infection, while MMV-rNS1 antigen can be used in generic ELISA for a variety of rodent parvoviruses. The higher sensitivity of MPV-rVP2 ELISA than conventional ELISA for detecting seroconversion to MPV in oronasally infected mice as well as in cage mates suggests the usefulness of MPV-rVP2 ELISA in quarantine and microbiological monitoring of MPV infection in laboratory mice.
Mahabir, E; Bulian, D; Needham, J; Schmidt, J
2009-09-01
The risk of transmission of mouse minute virus (MMV) to recipients of murine embryos arising from in vitro fertilization (IVF) of cumulus-enclosed oocytes (CEOs) or without cumulus cells (CDOs) in the presence of MMV-exposed (10(4) TCID(50) [mean tissue culture infective dose]/ml MMVp [prototype strain of MMV]) spermatozoa was evaluated. Also, the time after embryo transfer to detection of MMV antibody and the presence of MMV DNA in the mesenteric lymph nodes of recipients and pups were investigated. All mice were MMV free, but two seropositive recipients and four seropositive pups were found in the group with CDOs. With regard to the CEOs, two of 11 holding drops and five of 11 groups of embryos were MMV positive using PCR, while neither holding drops nor embryos carried infectious MMVp, as evidenced by the in vitro infectivity assay. From IVF with CDOs, five of 14 holding drops and four of nine groups of embryos were MMV positive, while one of 14 holding drops and no embryos carried infectious MMVp. When 10(5) cumulus cells were analyzed 5 h after exposure to 10(4) TCID(50)/ml MMVp, cells had an average titer of 10(4) TCID(50)/ml MMVp. The present data show that, in contrast to CDOs, 2-cell embryos from CEOs did not transmit infectious MMVp to the holding drops and to recipients. This observation is due to the presence of cumulus cells during the IVF process that reduce entry of MMV into the zona pellucida and absorb some of the virus. These data further confirm the efficacy of the IVF procedure in producing embryos that are free of infectious virus, leading to virus-free seronegative recipients and rederived pups.
Vallières, Cindy
2017-01-01
ABSTRACT To cope with growing resistance to current antimalarials, new drugs with novel modes of action are urgently needed. Molecules targeting protein synthesis appear to be promising candidates. We identified a compound (MMV665909) from the Medicines for Malaria Venture (MMV) Malaria Box of candidate antimalarials that could produce synergistic growth inhibition with the aminoglycoside antibiotic paromomycin, suggesting a possible action of the compound in mRNA mistranslation. This mechanism of action was substantiated with a Saccharomyces cerevisiae model using available reporters of mistranslation and other genetic tools. Mistranslation induced by MMV665909 was oxygen dependent, suggesting a role for reactive oxygen species (ROS). Overexpression of Rli1 (a ROS-sensitive, conserved FeS protein essential in mRNA translation) rescued inhibition by MMV665909, consistent with the drug's action on translation fidelity being mediated through Rli1. The MMV drug also synergized with major quinoline-derived antimalarials which can perturb amino acid availability or promote ROS stress: chloroquine, amodiaquine, and primaquine. The data collectively suggest translation fidelity as a novel target of antimalarial action and support MMV665909 as a promising drug candidate. PMID:28652237
Susceptibility of mouse minute virus to inactivation by heat in two cell culture media types.
Schleh, Marc; Romanowski, Peter; Bhebe, Prince; Zhang, Li; Chinniah, Shivanthi; Lawrence, Bill; Bashiri, Houman; Gaduh, Asri; Rajurs, Viveka; Rasmussen, Brian; Chuck, Alice; Dehghani, Houman
2009-01-01
Viral contaminations of biopharmaceutical manufacturing cell culture facilities are a significant threat and one for which having a risk mitigation strategy is highly desirable. High temperature, short time (HTST) mammalian cell media treatment may potentially safeguard manufacturing facilities from such contaminations. HTST is thought to inactivate virions by denaturing proteins of the viral capsid, and there is evidence that HTST provides ample virucidal efficacy against nonenveloped or naked viruses such as mouse minute virus (MMV), a parvovirus. The aim of the studies presented herein was to further delineate the susceptibility of MMV, known to have contaminated mammalian cell manufacturing facilities, to heat by exposing virus-spiked cell culture media to a broad range of temperatures and for various times of exposure. The results of these studies show that HTST is capable of inactivating MMV by three orders of magnitude or more. Thus, we believe that HTST is a useful technology for the purposes of providing a barrier to adventitious contamination of mammalian cell culture processes in the biopharmaceutical industry. 2009 American Institute of Chemical Engineers
Barandoc-Alviar, Karen; Ramirez, Girly M.; Rotenberg, Dorith; Whitfield, Anna E.
2016-01-01
The corn planthopper, Peregrinus maidis (Ashmead) (Hemiptera: Delphacidae), transmits Maize mosaic rhabdovirus (MMV), an important pathogen of maize and sorghum, in a persistent propagative manner. To better understand the vectorial capacity of P. maidis, we determined the efficiency of MMV acquisition by nymphal and adult stages, and characterized MMV titer through development. Acquisition efficiency, i.e., proportion of insects that acquired the virus, was determined by reverse transcriptase polymerase chain reaction (RT-PCR) and virus titer of individual insects was estimated by quantitative RT-PCR. Acquisition efficiency of MMV differed significantly between nymphs and adults. MMV titer increased significantly over time and throughout insect development from nymphal to adult stage, indication of virus replication in the vector during development. There was a positive association between the vector developmental stage and virus titer. Also, the average titer in male insects was threefold higher than female titers, and this difference persisted up to 30 d post adult eclosion. Overall, our findings indicate that nymphs are more efficient than adults at acquiring MMV and virus accumulated in the vector over the course of nymphal development. Furthermore, sustained infection over the lifespan of P. maidis indicates a potentially high capacity of this vector to transmit MMV. PMID:28076276
Ammar, El-Desouky; Hogenhout, Saskia A
2008-01-01
To investigate the dissemination route of Maize mosaic virus (MMV, Rhabdoviridae) in its planthopper vector Peregrinus maidis (Delphacidae, Hemiptera), temporal and spatial distribution of MMV was studied by immunofluorescence confocal laser scanning microscopy following 1-week acquisition feeding of planthoppers on infected plants. MMV was detected 1-week post first access to diseased plants (padp) in the midgut and anterior diverticulum, 2-week padp in the esophagus, nerves, nerve ganglia and visceral muscles, and 3-week padp in hemocytes, tracheae, salivary glands and other tissues. MMV is neurotropic in P. maidis; infection was more extensive in the nervous system compared to other tissues. A significantly higher proportion of planthoppers had infected midguts (28.1%) compared to those with infected salivary glands (20.4%) or to those that transmitted MMV (15.7%), suggesting the occurrence of midgut and salivary gland barriers to MMV transmission in P. maidis. In this planthopper, the esophagus and anterior diverticulum are located between the compound ganglionic mass and the salivary glands. We postulate that MMV may overcome transmission barriers in P. maidis by proceeding from the midgut to the anterior diverticulum and esophagus, and from these to the salivary glands via the nervous system: a neurotropic route similar to that of some vertebrate-infecting rhabdoviruses.
The Quest CCS Project - MMV Technology Deployment Through Two Years of Operation
NASA Astrophysics Data System (ADS)
O'Brien, S.
2017-12-01
In September 2012, Shell, on behalf of the Athabasca Oil Sands Project venture (Shell Canada Energy, Chevron Canada Limited, Marathon Oil Canada Corporation), announced that it was proceeding to construct the Quest Carbon Capture and Storage (CCS) project near Fort Saskatchewan. Quest is the world's first large-scale commercial application of CCS at an oil sands operation, and it is now capturing more than one million tonnes of CO2 per year from the Scotford Upgrader. It is a fully integrated project, involving CO2 capture at the bitumen upgrader, transportation along a 65 km pipeline, and CO2 storage in a deep saline aquifer (the Basal Cambrian Sands). Construction was completed in August 2015, and the Quest project was certified for commercial operation in September 2015. The Measurement, Monitoring and Verification (MMV) program for Quest is comprehensive, with a variety of technologies being used to monitor the atmosphere, hydrosphere, biosphere and geosphere. These include a Lightsource system for atmospheric monitoring, extensive groundwater sampling, DAS VSPs to assess the development of the CO2 plume, a microseismic array to measure any induced seismic activity, and temperature and pressure gauges for reservoir monitoring. Over two years of operations, this program has been optimized to address key risks while improving operational efficiency. Quest has now successfully captured and stored more than 2 million tonnes of CO2 with no MMV indications of any storage issues.
Complete genome sequence of a tomato infecting tomato mottle mosaic virus in New York
USDA-ARS?s Scientific Manuscript database
Complete genome sequence of an emerging isolate of tomato mottle mosaic virus (ToMMV) infecting experimental nicotianan benthamiana plants in up-state New York was obtained using small RNA deep sequencing. ToMMV_NY-13 shared 99% sequence identity to ToMMV isolates from Mexico and Florida. Broader d...
Barandoc-Alviar, Karen; Ramirez, Girly M; Rotenberg, Dorith; Whitfield, Anna E
2016-01-01
The corn planthopper, Peregrinus maidis (Ashmead) (Hemiptera: Delphacidae), transmits Maize mosaic rhabdovirus (MMV), an important pathogen of maize and sorghum, in a persistent propagative manner. To better understand the vectorial capacity of P. maidis, we determined the efficiency of MMV acquisition by nymphal and adult stages, and characterized MMV titer through development. Acquisition efficiency, i.e., proportion of insects that acquired the virus, was determined by reverse transcriptase polymerase chain reaction (RT-PCR) and virus titer of individual insects was estimated by quantitative RT-PCR. Acquisition efficiency of MMV differed significantly between nymphs and adults. MMV titer increased significantly over time and throughout insect development from nymphal to adult stage, indication of virus replication in the vector during development. There was a positive association between the vector developmental stage and virus titer. Also, the average titer in male insects was threefold higher than female titers, and this difference persisted up to 30 d post adult eclosion. Overall, our findings indicate that nymphs are more efficient than adults at acquiring MMV and virus accumulated in the vector over the course of nymphal development. Furthermore, sustained infection over the lifespan of P. maidis indicates a potentially high capacity of this vector to transmit MMV. © The Author 2016. Published by Oxford University Press on behalf of the Entomological Society of America.
Systematic review of military motor vehicle crash-related injuries.
Krahl, Pamela L; Jankosky, Christopher J; Thomas, Richard J; Hooper, Tomoko I
2010-01-01
Motor vehicle crashes account for nearly one third of U.S. military fatalities annually. The objective of this review is to summarize the published evidence on injuries due specifically to military motor vehicle (MMV) crashes. A search of 18 electronic databases identified English language publications addressing MMV crash-related injuries between 1970 and 2006 that were available to the general public. Documents limited in distribution to military or government personnel were not evaluated. Relevant articles were categorized by study design. The search identified only 13 studies related specifically to MMV crashes. Most were case reports or case series (n=8); only one could be classified as an intervention study. Nine of the studies were based solely on data from service-specific military safety centers. Few studies exist on injuries resulting from crashes of military motor vehicles. Epidemiologic studies that assess injury rates, type, severity, and risk factors are needed, followed by studies to evaluate targeted interventions and prevention strategies. Interventions currently underway should be evaluated for effectiveness, and those proven effective in the civilian community, such as graduated driver licensing, should be considered for implementation and evaluation in military populations. Published by Elsevier Inc.
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.
Paquet, Tanya; Le Manach, Claire; Cabrera, Diego González; Younis, Yassir; Henrich, Philipp P; Abraham, Tara S; Lee, Marcus C S; Basak, Rajshekhar; Ghidelli-Disse, Sonja; Lafuente-Monasterio, María José; Bantscheff, Marcus; Ruecker, Andrea; Blagborough, Andrew M; Zakutansky, Sara E; Zeeman, Anne-Marie; White, Karen L; Shackleford, David M; Mannila, Janne; Morizzi, Julia; Scheurer, Christian; Angulo-Barturen, Iñigo; Martínez, María Santos; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Reader, Janette; Botha, Mariette; Dechering, Koen J; Sauerwein, Robert W; Tungtaeng, Anchalee; Vanachayangkul, Pattaraporn; Lim, Chek Shik; Burrows, Jeremy; Witty, Michael J; Marsh, Kennan C; Bodenreider, Christophe; Rochford, Rosemary; Solapure, Suresh M; Jiménez-Díaz, María Belén; Wittlin, Sergio; Charman, Susan A; Donini, Cristina; Campo, Brice; Birkholtz, Lyn-Marie; Hanson, Kirsten K; Drewes, Gerard; Kocken, Clemens H M; Delves, Michael J; Leroy, Didier; Fidock, David A; Waterson, David; Street, Leslie J; Chibale, Kelly
2017-04-26
As part of the global effort toward malaria eradication, phenotypic whole-cell screening revealed the 2-aminopyridine class of small molecules as a good starting point to develop new antimalarial drugs. Stemming from this series, we found that the derivative, MMV390048, lacked cross-resistance with current drugs used to treat malaria. This compound was efficacious against all Plasmodium life cycle stages, apart from late hypnozoites in the liver. Efficacy was shown in the humanized Plasmodium falciparum mouse model, and modest reductions in mouse-to-mouse transmission were achieved in the Plasmodium berghei mouse model. Experiments in monkeys revealed the ability of MMV390048 to be used for full chemoprotection. Although MMV390048 was not able to eliminate liver hypnozoites, it delayed relapse in a Plasmodium cynomolgi monkey model. Both genomic and chemoproteomic studies identified a kinase of the Plasmodium parasite, phosphatidylinositol 4-kinase, as the molecular target of MMV390048. The ability of MMV390048 to block all life cycle stages of the malaria parasite suggests that this compound should be further developed and may contribute to malaria control and eradication as part of a single-dose combination treatment. Copyright © 2017, American Association for the Advancement of Science.
Modified Monovision With Spherical Aberration to Improve Presbyopic Through-Focus Visual Performance
Zheleznyak, Len; Sabesan, Ramkumar; Oh, Je-Sun; MacRae, Scott; Yoon, Geunyoung
2013-01-01
Purpose. To investigate the impact on visual performance of modifying monovision with monocularly induced spherical aberration (SA) to increase depth of focus (DoF), thereby enhancing binocular through-focus visual performance. Methods. A binocular adaptive optics (AO) vision simulator was used to correct both eyes' native aberrations and induce traditional (TMV) and modified (MMV) monovision corrections. TMV was simulated with 1.5 diopters (D) of anisometropia (dominant eye at distance, nondominant eye at near). Zernike primary SA was induced in the nondominant eye in MMV. A total of four MMV conditions were tested with various amounts of SA (±0.2 and ±0.4 μm) and fixed anisometropia (1.5 D). Monocular and binocular visual acuity (VA) and contrast sensitivity (CS) at 10 cyc/deg and binocular summation were measured through-focus in three cyclopledged subjects with 4-mm pupils. Results. MMV with positive SA had a larger benefit for intermediate distances (1.5 lines at 1.0 D) than with negative SA, compared with TMV. Negative SA had a stronger benefit in VA at near. DoF of all MMV conditions was 3.5 ± 0.5 D (mean) as compared with TMV (2.7 ± 0.3 D). Through-focus CS at 10 cyc/deg was significantly reduced with MMV as compared to TMV only at intermediate object distances, however was unaffected at distance. Binocular summation was absent at all object distances except 0.5 D, where it improved in MMV by 19% over TMV. Conclusions. Modified monovision with SA improves through-focus VA and DoF as compared with traditional monovision. Binocular summation also increased as interocular similarity of image quality increased due to extended monocular DoF. PMID:23557742
Corral, Maxime G; Leroux, Julie; Tresch, Stefan; Newton, Trevor; Stubbs, Keith A; Mylne, Joshua S
2018-07-01
To fight herbicide-resistant weeds, new herbicides are needed; particularly ones with new modes of action. Building on the revelation that many antimalarial drugs are herbicidal, here we focus on the Medicines for Malaria Venture antimalarial lead compound MMV007978 that has herbicidal activity against the model plant Arabidopsis thaliana. Twenty-two variations of the lead compound thiophenyl motif revealed that change was tolerated provided ring size and charge were retained. MMV007978 was active against select monocot and dicot weeds, and physiological profiling indicated that its mode of action is related to germination and cell division. Of interest is the fact that the compound has a profile that is currently not found among known herbicides. We demonstrate that the antimalarial compound MMV007978 is also herbicidal and that exploiting lead compounds that are often understudied could lead to the identification of interesting herbicidal scaffolds. Further structural investigation of MMV007978 could provide improved herbicidal chemistries with a potential new mode of action. © 2018 Society of Chemical Industry. © 2018 Society of Chemical Industry.
Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M; Koolen, Karin J M; Dechering, Koen J; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
2018-04-25
Therapies addressing multiple stages of Plasmodium falciparum life cycle are highly desirable for implementing malaria elimination strategies. MMV019918 (1, 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine) was selected from the MMV Malaria Box for its dual activity against both asexual stages and gametocytes. In-depth structure-activity relationship studies and cytotoxicity evaluation led to the selection of 25 for further biological investigation. The potential transmission blocking activity of 25 versus P. falciparum was confirmed through the standard membrane-feeding assay. Both 1 and 25 significantly prolonged atrioventricular conduction time in Langendorff-isolated rat hearts, and showed inhibitory activity of Ba 2+ current through Ca v 1.2 channels. An in silico target-fishing study suggested the enzyme phosphoethanolamine methyltransferase (PfPMT) as a potential target. However, compound activity against PfPMT did not track with the antiplasmodial activity, suggesting the latter activity relies on a different molecular target. Nevertheless, 25 showed interesting activity against PfPMT, which could be an important starting point for the identification of more potent inhibitors active against both sexual and asexual stages of the parasite. Copyright © 2018 Elsevier Masson SAS. All rights reserved.
Higashi, Clesson H V; Bressan, Alberto
2013-07-01
To maximize fitness, plant pathogenic viruses may manipulate their arthropod vectors through direct and indirect (via the host plant) interactions. For many virus-vector-plant associations, insect feeding does not always lead to virus acquisition. In fact, many plant viruses, especially those that propagate into their vectors, are acquired at low rates. Although the majority of insects colonizing an infected plant escape from viral infection, they are still exposed to the indirect effects (i.e. the effect of plant metabolism modification following virus infection). Little information has been reported on the effects of plant viruses on insects that become infected versus those that do not (here referred to as "exposed"). The effect that the Maize mosaic virus (MMV) (Rhabdoviridae) exerts on the fitness and wing dimorphism of the planthopper vector, Peregrinus maidis (Hemiptera, Delphacidae), that developed on leaves from either young or old corn plants was examined. MMV exerted non-consistent to minimal direct effects on developmental time, longevity, nymphal mortality and fecundity. In addition, some small yet significant fitness costs were encountered by exposed planthoppers to escape MMV infection. Furthermore, a significantly higher proportion of macropters over brachypters were produced on MMV-infected old leaves compared with healthy leaves of a similar age. We conclude that the virus influences the dispersal of the vector, promoting a larger production of macropters at the costs of brachypters at a late stage of the plant infection. Because MMV infection in planthoppers did not segregate by wing morphotype, our results indicate that the dispersal of both infected and exposed planthoppers was a likely consequence of the indirect effects of MMV.
Understanding the mechanism of resistance breaking on tomato by Tomato mottle mosaic virus
USDA-ARS?s Scientific Manuscript database
Tomato mottle mosaic virus (ToMMV) has broadened it’s distribution around the world. In our previous work, we observed a partial resistance breaking by ToMMV on tomato. To understand the mechanism of this resistance breaking, we carried out comparative analysis through Sanger sequencing, genotyping ...
Carbon-14 radiolabeling and tissue distribution evaluation of MMV390048.
Sonopo, Molahlehi S; Pillay, Adushan; Chibale, Kelly; Marjanovic-Painter, Biljana; Donini, Cristina; Zeevaart, Jan R
2016-12-01
The antimalarial compound MMV390048 ([ 14 C]-11) was labeled with carbon-14 isotope via a 3-step synthesis. It was obtained in a 15.5% radiochemical overall yield from carbon-14 labeled methyl iodide with a radiochemical purity of >99%. After single oral administration of [ 14 C]-11 to albino and pigmented rats its tissue distribution profile was studied. Tissue distribution results showed high local exposure in the GI tract and excretory organs but low exposure of all other tissues. The radioactivity uptake was higher in the eyes of the pigmented rats than in the eyes of the albino rats at all-time points. The highest accumulation reached in the eyes of the pigmented rats was 0.46% at 6 hours. However, these levels are still very low as compared to the other organs studied. There was very little radioactivity from MMV390048 ([ 14 C]-11) present in the skin of both the albino and pigmented rats. The results obtained are supportive of further development of MMV390048 as a potential antimalarial compound. Copyright © 2016 John Wiley & Sons, Ltd.
Higashi, C H V; Brewbaker, J L; Bressan, A
2013-08-01
Crops that are resistant to pests and pathogens are cost-effective for the management of pests and diseases. A corn (Zea mays L.) breeding program conducted in Hawaii has identified a source of heritable resistance to maize mosaic virus (MMV) (Rhabdoviridae: Nucleorhabdovirus). This resistance is controlled by the gene Mv, which has been shown to have a codominant action. To date, no studies have examined whether the resistance associated with this gene affects only MMV or whether it also affects the insect vector, the corn planthopper Peregrinus maidis (Ashmead) (Hemiptera: Delphacidae). Here, we examined the life history of the corn planthopper and its ability to transmit MMV on near isogenic lines that were homozygous dominant (Mv/Mv), homozygous recessive (mv/mv), or heterozygous (Mv/mv) for the gene. A field trial was also conducted to study the colonization of the corn plants with different genotypes by the planthopper. Although field observations revealed slightly lower densities ofplanthoppers on corn with the genotype Mv/Mv than on the inbreds with the genotype mv/mv and their hybrids with the genotype Mv/mv, laboratory assays showed no effects of the gene on planthopper development, longevity, or fecundity. In the field, the corn lines Mv/Mv had a lower incidence of MMV-infected plants. However, in the greenhouse, the transmission of MMV to corn seedlings did not differ across the near isogenic lines, although the corn lines Mv/Mv showed a delayed onset of symptoms compared with the corn lines mv/mv and Mv/mv. The acquisition of MMV by corn planthoppers on the corn genotypes Mv/Mv and Mv/mv averaged 0.2, whereas the acquisition on the corn genotypes mv/mv averaged > 0.3. Our results show that the Mv gene does not influence the fitness of the planthopper vector, suggesting that it may confer resistance by other means, possibly by limiting virus replication or movement within the host plant.
[Effectiveness of a combined live mumps-measles vaccine].
Unanov, S S; Korzh, Iu N; Dorofeev, V M; Iuminova, N V; Myshliaeva, L A
1987-01-01
The reactogenic and areactogenic properties of a live combined mumps-measles vaccine (MMV) prepared in primary cultures of Japanese quail embryo cells from attenuated strains of mumps (L-3) and measles (L-16) viruses were under study. The observations involved 648 infants varying in ages from 1 to 3 years, seronegative to measles and mumps viruses, without the history of the disease and vaccinations against these infections or contraindications to vaccinations. The infants were vaccinated with 5 batches of MMV with different portions of the mumps and measles components. The vaccinees and controls (placebo injections) were observed for 30 days postvaccination. The live MMV was shown to be a safe, well tolerated preparation with low reactogenicity and a high antigenic activity.
Joint Smoothed l₀-Norm DOA Estimation Algorithm for Multiple Measurement Vectors in MIMO Radar.
Liu, Jing; Zhou, Weidong; Juwono, Filbert H
2017-05-08
Direction-of-arrival (DOA) estimation is usually confronted with a multiple measurement vector (MMV) case. In this paper, a novel fast sparse DOA estimation algorithm, named the joint smoothed l 0 -norm algorithm, is proposed for multiple measurement vectors in multiple-input multiple-output (MIMO) radar. To eliminate the white or colored Gaussian noises, the new method first obtains a low-complexity high-order cumulants based data matrix. Then, the proposed algorithm designs a joint smoothed function tailored for the MMV case, based on which joint smoothed l 0 -norm sparse representation framework is constructed. Finally, for the MMV-based joint smoothed function, the corresponding gradient-based sparse signal reconstruction is designed, thus the DOA estimation can be achieved. The proposed method is a fast sparse representation algorithm, which can solve the MMV problem and perform well for both white and colored Gaussian noises. The proposed joint algorithm is about two orders of magnitude faster than the l 1 -norm minimization based methods, such as l 1 -SVD (singular value decomposition), RV (real-valued) l 1 -SVD and RV l 1 -SRACV (sparse representation array covariance vectors), and achieves better DOA estimation performance.
Fokou, Patrick V. T.; Tchokouaha, Lauve R. Y.; Spangenberg, Thomas; Mfopa, Alvine N.; Kouipou, Ruffin M. T.; Mbouna, Cedric J.; Donfack, Valerie F. Donkeng; Zollo, Paul H. A.
2014-01-01
Toxoplasmosis and amebiasis are important public health concerns worldwide. The drugs currently available to control these diseases have proven limitations. Therefore, innovative approaches should be adopted to identify and develop new leads from novel scaffolds exhibiting novel modes of action. In this paper, we describe results from the screening of compounds in the Medicines for Malaria Venture (MMV) open access Malaria Box in a search for new anti-Toxoplasma and anti-Entamoeba agents. Standard in vitro phenotypic screening procedures were adopted to assess their biological activities. Seven anti-Toxoplasma compounds with a 50% inhibitory concentration (IC50) of <5 μM and selectivity indexes (SI) of >6 were identified. The most interesting compound was MMV007791, a piperazine acetamide, which has an IC50 of 0.19 μM and a selectivity index of >157. Also, we identified two compounds, MMV666600 and MMV006861, with modest activities against Entamoeba histolytica, with IC50s of 10.66 μM and 15.58 μM, respectively. The anti-Toxoplasma compounds identified in this study belong to scaffold types different from those of currently used drugs, underscoring their novelty and potential as starting points for the development of new antitoxoplasmosis drugs with novel modes of action. PMID:25049259
Nagai, Alice; Duarte, Lígia M L; Chaves, Alexandre L R; Alexandre, Maria A V; Ramos-González, Pedro L; Chabi-Jesus, Camila; Harakava, Ricardo; Dos Santos, Déborah Y A C
2018-05-10
The complete nucleotide sequence of an isolate of tomato mottle mosaic virus (ToMMV) was determined. The virus, originally isolated from symptomatic tomato plants found in a county near the city of São Paulo, Brazil, has a genome with 99% nucleotide sequence identity with ToMMV from Mexico, China, Spain, and the United States. Copyright © 2018 Nagai et al.
Ch’ng, Jun-Hong; Moll, Kirsten; Quintana, Maria del Pilar; Chan, Sherwin Chun Leung; Masters, Ellen; Moles, Ernest; Liu, Jianping; Eriksson, Anders B.; Wahlgren, Mats
2016-01-01
The spread of artemisinin-resistant parasites could lead to higher incidence of patients with malaria complications. However, there are no current treatments that directly dislodge sequestered parasites from the microvasculature. We show that four common antiplasmodial drugs do not disperse rosettes (erythrocyte clusters formed by malaria parasites) and therefore develop a cell-based high-throughput assay to identify potential rosette-disrupting compounds. A pilot screen of 2693 compounds identified Malaria Box compound MMV006764 as a potential candidate. Although it reduced rosetting by a modest 20%, MMV006764 was validated to be similarly effective against both blood group O and A rosettes of three laboratory parasite lines. Coupled with its antiplasmodial activity and drug-likeness, MMV006764 represents the first small-molecule compound that disrupts rosetting and could potentially be used in a resource-limited setting to treat patients deteriorating rapidly from malaria complications. Such dual-action drugs that simultaneously restore microcirculation and reduce parasite load could significantly reduce malaria morbidity and mortality. PMID:27403804
Bilad, M R; Discart, V; Vandamme, D; Foubert, I; Muylaert, K; Vankelecom, Ivo F J
2013-06-01
This study was performed to investigate the effectiveness of submerged microfiltration to harvest both a marine diatom Phaeodactylum tricornutum and a Chlorella vulgaris in a recently developed magnetically induced membrane vibrating (MMV) system. We assess the filtration performance by conducting the improved flux step method (IFM), fed-batch concentration filtrations and membrane fouling autopsy using two lab-made membranes with different porosity. The full-scale energy consumption was also estimated. Overall results suggest that the MMV offers a good fouling control and the process was proven to be economically attractive. By combining the membrane filtration (15× concentration) with centrifugation to reach a final concentration of 25% w/v, the energy consumption to harvest P. tricornutum and C. vulgaris was, respectively, as low as 0.84 and 0.77kWh/m(3), corresponding to 1.46 and 1.39 kWh/kg of the harvested biomass. Copyright © 2013 Elsevier Ltd. All rights reserved.
Monitoring Shallow Subsurface CO2 Migration using Electrical Imaging Technique, Pilot Site in Brazil
NASA Astrophysics Data System (ADS)
Oliva, A.; Chang, H. K.; Moreira, A.
2013-12-01
Carbon Capture and Geological Sequestration (CCGS or CCS) is one of the main technological strategies targeting Greenhouse Gases (GHG) emissions reduction, with special emphasis on carbon dioxide (CO2) coming from industrial sources. CCGS integrates the so called Carbon Management Strategies, as indicated by the Intergovernmental Panel on Climate Change (IPCC), and is the basis of main technical route likely to enable substantial emission reduction in a safe, quick and cost-effective way. Currently one of the main challenges in the area of CO2 storage research is to grant the development, testing and validation of accurate and efficient measuring, monitoring and verification (MMV) techniques to be deployed at the final storage site, targeting maximum storage efficiency at the minimal leakage risk levels. The implementation of the first CO2 MMV field lab in Brazil, located in Florianópolis, Santa Catarina state, offered an excellent opportunity for running controlled release experiments in a real open air environment. The purpose of this work is to present the results of a time lapse monitoring experiment of CO2 migration in both saturated and unsaturated sand-rich sediments, using electrical imaging technique. The experiment covered an area of approximately 6300 m2 and CO2 was continuously injected at depth of 8 m, during 12 days, at an average rate of 90 g/ day, totalizing 1080 g of injected CO2. 2D and 3D electrical images using Wenner array were acquired daily during 13 consecutive days. Comparison of post injection electrical imaging results with pre injection images shows change in resistivity values consistent with migration pathways of CO2. A pronounced increase in resistivity values (up to ~ 500 ohm.m) with respect to the pre-injection values occurs in the vicinity of the injection well. Background values of 530 ohm.m have changed to 1118 ohm.m, right after injection. Changes in resistivity values progressively diminish outward of the well, following groundwater flow path.
Linked halokinesis and mud volcanism at the Mercator mud volcano, Gulf of Cadiz
NASA Astrophysics Data System (ADS)
Perez-Garcia, Carolina; Berndt, Christian; Klaeschen, Dirk; Mienert, Jürgen; Haffert, Laura; Depreiter, Davy; Haeckel, Matthias
2011-05-01
Mud volcanoes are seafloor expressions of focused fluid flow that are common in compressional tectonic settings. New high-resolution 3-D seismic data from the Mercator mud volcano (MMV) and an adjacent buried mud volcano (BMV) image the internal structure of the top 800 m of sediment at both mud volcanoes, revealing that both are linked and have been active episodically. The total volumes of extruded mud range between 0.15 and 0.35 km3 and 0.02-0.05 km3 for the MMV and the BMV, respectively. The pore water composition of surface sediment samples suggests that halokinesis has played an important role in the evolution of the mud volcanoes. We propose that erosion of the top of the Vernadsky Ridge that underlies the mud volcanoes activated salt movement, triggering deep migration of fluids, dissolution of salt, and sediment liquefaction and mobilization since the end of the Pliocene. Since beginning of mud volcanism in this area, the mud volcanoes erupted four times while there was only one reactivation of salt tectonics. This implies that there are other mechanisms that trigger mud eruptions. The stratigraphic relationship of mudflows from the MMV and BMV indicates that the BMV was triggered by the MMV eruptions. This may either be caused by loading-induced hydrofracturing within the BMV or due to a common feeder system for both mud volcanoes. This study shows that the mud volcanoes in the El Arraiche mud volcano field are long-lived features that erupt with intervals of several tens of thousands of years.
NASA Astrophysics Data System (ADS)
He, Xingyu; Tong, Ningning; Hu, Xiaowei
2018-01-01
Compressive sensing has been successfully applied to inverse synthetic aperture radar (ISAR) imaging of moving targets. By exploiting the block sparse structure of the target image, sparse solution for multiple measurement vectors (MMV) can be applied in ISAR imaging and a substantial performance improvement can be achieved. As an effective sparse recovery method, sparse Bayesian learning (SBL) for MMV involves a matrix inverse at each iteration. Its associated computational complexity grows significantly with the problem size. To address this problem, we develop a fast inverse-free (IF) SBL method for MMV. A relaxed evidence lower bound (ELBO), which is computationally more amiable than the traditional ELBO used by SBL, is obtained by invoking fundamental property for smooth functions. A variational expectation-maximization scheme is then employed to maximize the relaxed ELBO, and a computationally efficient IF-MSBL algorithm is proposed. Numerical results based on simulated and real data show that the proposed method can reconstruct row sparse signal accurately and obtain clear superresolution ISAR images. Moreover, the running time and computational complexity are reduced to a great extent compared with traditional SBL methods.
Novel magnetically induced membrane vibration (MMV) for fouling control in membrane bioreactors.
Bilad, Muhammad R; Mezohegyi, Gergo; Declerck, Priscilla; Vankelecom, Ivo F J
2012-01-01
Conventional submerged membrane bioreactors (MBRs) rely on the coarse bubbles aeration to generate shear at the liquid-membrane interface to limit membrane fouling. Unfortunately, it is a very energy consuming method, still often resulting in a rapid decrease of membrane permeability and consequently in higher expenses. In this paper, the feasibility of a novel magnetically induced membrane vibration (MMV) system was studied in a lab-scale MBR treating synthetic wastewater. The effects on membrane fouling of applied electrical power of different operation strategies, of membrane flux and of the presence of multiple membranes on one vibrating engine on membrane fouling were investigated. The filtration performance was evaluated by determining the filtration resistance profiles and critical flux. The results showed clear advantages of the vibrating system over conventional MBR processes by ensuring higher fluxes at lower fouling rates. Intermittent vibration was found a promising strategy for both efficient fouling control and significant energy saving. The optimised MMV system is presumed to lead to significant energy and cost reduction in up-scaled MBR operations. Copyright © 2011 Elsevier Ltd. All rights reserved.
Discovery of New Inhibitors of Toxoplasma gondii via the Pathogen Box
Spalenka, Jérémy; Escotte-Binet, Sandie; Bakiri, Ali; Hubert, Jane; Renault, Jean-Hugues; Velard, Frédéric; Duchateau, Simon; Aubert, Dominique; Huguenin, Antoine
2017-01-01
ABSTRACT Toxoplasma gondii is a cosmopolitan protozoan parasite which affects approximately 30% of the population worldwide. The drugs currently used against toxoplasmosis are few in number and show several limitations, such as drug intolerance, poor bioavailability, or drug resistance mechanism developed by the parasite. Thus, it is important to find new compounds able to inhibit parasite invasion or proliferation. In this study, the 400 compounds of the open-access Pathogen Box, provided by the Medicines for Malaria Venture (MMV) foundation, were screened for their anti-Toxoplasma gondii activity. A preliminary in vitro screening performed over 72 h by an enzyme-linked immunosorbent assay (ELISA) revealed 15 interesting compounds that were effective against T. gondii at 1 μM. Their cytotoxicity was estimated on Vero cells, and their 50% inhibitory concentrations (IC50) were further calculated. As a result, eight anti-Toxoplasma gondii compounds with an IC50 of less than 2 μM and a selectivity index (SI) value of greater than 4 were identified. The most active was MMV675968, showing an IC50 of 0.02 μM and a selectivity index value equal to 275. Two other compounds, MMV689480 and MMV687807, also showed a good activity against T. gondii, with IC50s of 0.10 μM (SI of 86.6) and 0.15 μM (SI of 11.3), respectively. Structure-activity relationships for the eight selected compounds also were discussed on the basis of fingerprinting similarity measurements using the Tanimoto method. The anti-Toxoplasma gondii compounds highlighted here represent potential candidates for the development of new drugs that could be used against toxoplasmosis. PMID:29133550
Discovery of New Inhibitors of Toxoplasma gondii via the Pathogen Box.
Spalenka, Jérémy; Escotte-Binet, Sandie; Bakiri, Ali; Hubert, Jane; Renault, Jean-Hugues; Velard, Frédéric; Duchateau, Simon; Aubert, Dominique; Huguenin, Antoine; Villena, Isabelle
2018-02-01
Toxoplasma gondii is a cosmopolitan protozoan parasite which affects approximately 30% of the population worldwide. The drugs currently used against toxoplasmosis are few in number and show several limitations, such as drug intolerance, poor bioavailability, or drug resistance mechanism developed by the parasite. Thus, it is important to find new compounds able to inhibit parasite invasion or proliferation. In this study, the 400 compounds of the open-access Pathogen Box, provided by the Medicines for Malaria Venture (MMV) foundation, were screened for their anti- Toxoplasma gondii activity. A preliminary in vitro screening performed over 72 h by an enzyme-linked immunosorbent assay (ELISA) revealed 15 interesting compounds that were effective against T. gondii at 1 μM. Their cytotoxicity was estimated on Vero cells, and their 50% inhibitory concentrations (IC 50 ) were further calculated. As a result, eight anti- Toxoplasma gondii compounds with an IC 50 of less than 2 μM and a selectivity index (SI) value of greater than 4 were identified. The most active was MMV675968, showing an IC 50 of 0.02 μM and a selectivity index value equal to 275. Two other compounds, MMV689480 and MMV687807, also showed a good activity against T. gondii , with IC 50 s of 0.10 μM (SI of 86.6) and 0.15 μM (SI of 11.3), respectively. Structure-activity relationships for the eight selected compounds also were discussed on the basis of fingerprinting similarity measurements using the Tanimoto method. The anti- Toxoplasma gondii compounds highlighted here represent potential candidates for the development of new drugs that could be used against toxoplasmosis. Copyright © 2018 Spalenka et al.
Warach, Steven; Al-Rawi, Yasir; Furlan, Anthony J; Fiebach, Jochen B; Wintermark, Max; Lindstén, Annika; Smyej, Jamal; Bharucha, David B; Pedraza, Salvador; Rowley, Howard A
2012-09-01
The DIAS-2 study was the only large, randomized, intravenous, thrombolytic trial that selected patients based on the presence of ischemic penumbra. However, DIAS-2 did not confirm the positive findings of the smaller DEDAS and DIAS trials, which also used penumbral selection. Therefore, a reevaluation of the penumbra selection strategy is warranted. In post hoc analyses we assessed the relationships of magnetic resonance imaging-measured lesion volumes with clinical measures in DIAS-2, and the relationships of the presence and size of the diffusion-perfusion mismatch with the clinical effect of desmoteplase in DIAS-2 and in pooled data from DIAS, DEDAS, and DIAS-2. In DIAS-2, lesion volumes correlated with National Institutes of Health Stroke Scale (NIHSS) at both baseline and final time points (P<0.0001), and lesion growth was inversely related to good clinical outcome (P=0.004). In the pooled analysis, desmoteplase was associated with 47% clinical response rate (n=143) vs 34% in placebo (n=73; P=0.08). For both the pooled sample and for DIAS-2, increasing the minimum baseline mismatch volume (MMV) for inclusion increased the desmoteplase effect size. The odds ratio for good clinical response between desmoteplase and placebo treatment was 2.83 (95% confidence interval, 1.16-6.94; P=0.023) for MMV >60 mL. Increasing the minimum NIHSS score for inclusion did not affect treatment effect size. Pooled across all desmoteplase trials, desmoteplase appears beneficial in patients with large MMV and ineffective in patients with small MMV. These results support a modified diffusion-perfusion mismatch hypothesis for patient selection in later time-window thrombolytic trials. Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique Identifiers: NCT00638781, NCT00638248, NCT00111852.
Bilayer Effects of Antimalarial Compounds
Ramsey, Nicole B.; Andersen, Olaf S.
2015-01-01
Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested the 80 most potent compounds from the box for bilayer-mediated effects on membrane protein conformational changes (a measure of likely toxicity) in a gramicidin-based stopped flow fluorescence assay. Among the Malaria Box compounds tested, four compounds altered membrane properties (p< 0.05); MMV007384 stood out as a potent bilayer-perturbing compound that is toxic in many cell-based assays, suggesting that testing for membrane perturbation could help identify toxic compounds. In any case, MMV007384 should be approached with caution, if at all. PMID:26551613
Bilayer Effects of Antimalarial Compounds.
Ramsey, Nicole B; Andersen, Olaf S
2015-01-01
Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested the 80 most potent compounds from the box for bilayer-mediated effects on membrane protein conformational changes (a measure of likely toxicity) in a gramicidin-based stopped flow fluorescence assay. Among the Malaria Box compounds tested, four compounds altered membrane properties (p< 0.05); MMV007384 stood out as a potent bilayer-perturbing compound that is toxic in many cell-based assays, suggesting that testing for membrane perturbation could help identify toxic compounds. In any case, MMV007384 should be approached with caution, if at all.
Big Sky Carbon Sequestration Partnership
DOE Office of Scientific and Technical Information (OSTI.GOV)
Susan Capalbo
2005-12-31
The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership in Phase I are organized into four areas: (1) Evaluation of sources and carbon sequestration sinks that will be used to determine the location of pilot demonstrations in Phase II; (2) Development of GIS-based reporting framework that links with national networks; (3) Design of an integrated suite of monitoring, measuring, and verification technologies, market-based opportunities for carbon management, and an economic/risk assessmentmore » framework; (referred to below as the Advanced Concepts component of the Phase I efforts) and (4) Initiation of a comprehensive education and outreach program. As a result of the Phase I activities, the groundwork is in place to provide an assessment of storage capabilities for CO{sub 2} utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that complements the ongoing DOE research agenda in Carbon Sequestration. The geology of the Big Sky Carbon Sequestration Partnership Region is favorable for the potential sequestration of enormous volume of CO{sub 2}. The United States Geological Survey (USGS 1995) identified 10 geologic provinces and 111 plays in the region. These provinces and plays include both sedimentary rock types characteristic of oil, gas, and coal productions as well as large areas of mafic volcanic rocks. Of the 10 provinces and 111 plays, 1 province and 4 plays are located within Idaho. The remaining 9 provinces and 107 plays are dominated by sedimentary rocks and located in the states of Montana and Wyoming. The potential sequestration capacity of the 9 sedimentary provinces within the region ranges from 25,000 to almost 900,000 million metric tons of CO{sub 2}. Overall every sedimentary formation investigated has significant potential to sequester large amounts of CO{sub 2}. Simulations conducted to evaluate mineral trapping potential of mafic volcanic rock formations located in the Idaho province suggest that supercritical CO{sub 2} is converted to solid carbonate mineral within a few hundred years and permanently entombs the carbon. Although MMV for this rock type may be challenging, a carefully chosen combination of geophysical and geochemical techniques should allow assessment of the fate of CO{sub 2} in deep basalt hosted aquifers. Terrestrial carbon sequestration relies on land management practices and technologies to remove atmospheric CO{sub 2} where it is stored in trees, plants, and soil. This indirect sequestration can be implemented today and is on the front line of voluntary, market-based approaches to reduce CO{sub 2} emissions. Initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil Carbon (C) on rangelands, and forested, agricultural, and reclaimed lands. Rangelands can store up to an additional 0.05 mt C/ha/yr, while the croplands are on average four times that amount. Estimates of technical potential for soil sequestration within the region in cropland are in the range of 2.0 M mt C/yr over 20 year time horizon. This is equivalent to approximately 7.0 M mt CO{sub 2}e/yr. The forestry sinks are well documented, and the potential in the Big Sky region ranges from 9-15 M mt CO{sub 2} equivalent per year. Value-added benefits include enhanced yields, reduced erosion, and increased wildlife habitat. Thus the terrestrial sinks provide a viable, environmentally beneficial, and relatively low cost sink that is available to sequester C in the current time frame. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts in developing and implementing MMV technologies for geological and terrestrial sequestration reflect this concern. Research in Phase I has identified and validated best management practices for soil C in the Partnership region, and outlined a risk/cost effectiveness framework to make comparative assessments of each viable sink, taking into account economic costs, offsetting benefits, scale of sequestration opportunities, spatial and time dimensions, environmental risks, and long-term viability. This is the basis for the integrative analysis that will be undertaken in Phase II to work with industry, state and local governments and with the pilot demonstration projects to quantify the economic costs and risks associated with all opportunities for carbon storage in the Big Sky region. Scientifically sound MMV is critical for public acceptance of these technologies.« less
MMV in partnership: the Eurartesim® experience
2013-01-01
Background This case study describes how a public-private partnership between Medicines for Malaria Venture (MMV) and Sigma-Tau Industrie Farmaceutiche Riunite SpA achieved international regulatory approval for use of the fixed-dose artemisinin-based combination therapy dihydroartemisinin-piperaquine (Eurartesim®) for the treatment of malaria, enabling more widespread access to the medicine in malaria-endemic countries. Case description The combination of dihydroartemisinin and piperaquine demonstrated success in clinical trials for the treatment of malaria in Asia and Africa in the 2000s. However, as it had not been developed to international regulatory standards it was out of the reach of the majority of patients in disease-endemic countries, particularly those reliant on public healthcare systems supported by international donor funding. To overcome this, as of 2004 MMV worked in partnership with Sigma-Tau, Holleykin, Oxford University, the Institute of Tropical Medicine Antwerp, and the National Institute of Malaria Research India to develop the dihydroartemisinin-piperaquine combination to international standards. In 2011, the European Commission granted full marketing authorization to Sigma-Tau for Eurartesim. Discussion and evaluation The partnership between MMV, Sigma-Tau, and numerous other academic and industrial partners across the world, led to the successful development to EMA regulatory standards of a high-quality and highly efficacious anti-malarial treatment that otherwise would not have been possible. The dossier has also been submitted to the WHO for prequalification, and a safety statement to guide correct use of Eurartesim has been produced. In July 2012, the first delivery to a disease-endemic country was made to Cambodia, where the medicine is being used to treat patients and help counter the emergence of artemisinin resistance in the area. A paediatric dispersible formulation of Eurartesim is being developed, with the objective to submit the dossier to the EMA by the end of 2014. Conclusions The development of Eurartesim to international regulatory standards exemplifies the strengths of the product development partnership model in utilising the individual skills and expertise of partners with differing objectives to achieve a common goal. Successful uptake of Eurartesim by public health systems in malaria-endemic countries poses new challenges, which may require additional partnerships as we move forward. PMID:23782869
Rosario, Karyna; Capobianco, Heather; Ng, Terry Fei Fan; Breitbart, Mya; Polston, Jane E
2014-01-01
Whiteflies from the Bemisia tabaci species complex have the ability to transmit a large number of plant viruses and are some of the most detrimental pests in agriculture. Although whiteflies are known to transmit both DNA and RNA viruses, most of the diversity has been recorded for the former, specifically for the Begomovirus genus. This study investigated the total diversity of DNA and RNA viruses found in whiteflies collected from a single site in Florida to evaluate if there are additional, previously undetected viral types within the B. tabaci vector. Metagenomic analysis of viral DNA extracted from the whiteflies only resulted in the detection of begomoviruses. In contrast, whiteflies contained sequences similar to RNA viruses from divergent groups, with a diversity that extends beyond currently described viruses. The metagenomic analysis of whiteflies also led to the first report of a whitefly-transmitted RNA virus similar to Cowpea mild mottle virus (CpMMV Florida) (genus Carlavirus) in North America. Further investigation resulted in the detection of CpMMV Florida in native and cultivated plants growing near the original field site of whitefly collection and determination of its experimental host range. Analysis of complete CpMMV Florida genomes recovered from whiteflies and plants suggests that the current classification criteria for carlaviruses need to be reevaluated. Overall, metagenomic analysis supports that DNA plant viruses carried by B. tabaci are dominated by begomoviruses, whereas significantly less is known about RNA viruses present in this damaging insect vector.
Vogel, T; Leprêtre, P-M; Brechat, P-H; Lonsdorfer, E; Benetos, A; Kaltenbach, G; Lonsdorfer, J
2011-12-01
The aim of this study was to evaluate the efficiency of a short-term Intermittent Work Exercise Program (IWEP) among healthy elderly subjects. This longitudinal prospective study took place at the Strasbourg University Hospital geriatric department. One hundred and fifty older volunteers, previously determined as being free from cardiac and pulmonary disease, were separated into two age groups: the "young senior" (60.2 ± 3.1 yr) and the "older senior" groups (70.8 ± 5.2 yr). These groups were then subdivided by gender into the "young female senior", "young male senior" "older female senior" and "older male senior" groups. Before and after the IWEP, all subjects were asked to perform an incremental cycle exercise to obtain their first ventilatory threshold (VT1), maximal tolerated power (MTP), peak oxygen uptake (VO2peak) and maximal minute ventilation (MMV). The IWEP consisted of a 30-min cycling exercise which took place twice a week, and was divided into six 5-min stages consisting of 4 min at VT1 intensity and 1 min at 90% MTP. An assessment was made of the effects of the IWEP on maximal cardio-respiratory function (MTP, VO2peak, MMV) and endurance parameters (VT1, heart rate [HR] measured at pretraining VT1 and lactate concentrations at pre-training MTP). This short-term training program resulted in a significant increase of MTP (from 13.2% to 20.6%), VO2peak (from 8.9% to 16.6%) and MMV (from 11.1% to 21.8%) in all groups (p<0.05). VT1 improved from 21% at pretraining to 27%, while HR at pre-training VT1 as well as lactate concentrations at pre-training MTP decreased significantly in all groups (p<0.05). The post-training values for VO2peak and MMV of the "older seniors" were not significantly different (p>0.05) from the "young seniors" pre-training values for the same parameters. The most striking finding in this study is that after only 9 weeks, our short-term "individually-tailored" IWEP significantly improved both maximal cardio-respiratory function and endurance parameters in healthy, previously untrained seniors.
NASA Astrophysics Data System (ADS)
Denissenkov, Pavel A.; VandenBerg, Don A.; Kopacki, Grzegorz; Ferguson, Jason W.
2017-11-01
We present a new set of horizontal branch (HB) models computed with the MESA stellar evolution code. The models adopt α-enhanced Asplund et al. metal mixtures and include the gravitational settling of He. They are used in our HB population synthesis tool to generate theoretical distributions of HB stars in order to describe the multiple stellar populations in the globular clusters 47 Tuc, M3, and M13. The observed HB in 47 Tuc is reproduced very well by our simulations for [{Fe}/{{H}}]=-0.70 and [α /{Fe}]=+0.4 if the initial helium mass fraction varies by {{Δ }}{Y}0˜ 0.03, and approximately 21%, 37%, and 42% of the stars have {Y}0=0.257, 0.270, and 0.287, respectively. These simulations yield {(m-M)}V=13.27, implying an age near 13.0 Gyr. In the case of M3 and M13, our synthetic HBs for [{Fe}/{{H}}]=-1.55 and [α /{Fe}]=0.4 match the observed ones quite well if M3 has {{Δ }}{Y}0˜ 0.01 and {(m-M)}V=15.02, resulting in an age of 12.6 Gyr, whereas M13 has {{Δ }}{Y}0˜ 0.08 and {(m-M)}V=14.42, implying an age of 12.9 Gyr. Mass loss during giant branch evolution and {{Δ }}{Y}0 appear to be the primary second parameters for M3 and M13. New observations for seven of the nine known RR Lyrae in M13 are also reported. Surprisingly, periods predicted for the c-type variables tend to be too high (by up to ˜0.1 days).
Comparison of maternal milk (breastmilk) expression methods in an African nursery.
Slusher, Tina M; Slusher, Ida L; Keating, Elizabeth M; Curtis, Beverly A; Smith, Eleanor A; Orodriyo, Elizabeth; Awori, Sussane; Nakakeeto, Margaret K
2012-04-01
This study compares maternal milk volumes (MMVs) of Ugandan mothers whose infants were in a special care nursery and who used one of three maternal milk expression techniques: double electric breast pump, single non-electric manual breast pump, and hand breastmilk expression. A convenience sample of 161 Ugandan mothers of infants who were either too immature or ill to independently feed from the breast yet healthy enough to survive in an environment without ventilator support (birth weights, 0.84-3.8 kg) were assigned to one of three maternal milk expressions: Group 1, double electric breast pump (n=55); Group 2, single non-electric manual breast pump (n=59); and Group 3, hand breastmilk expression (n=47). Data were collected over a 7-day period (from day 1 postpartum to day 7 postpartum), and mean MMVs were measured and compared among the groups. The mean daily MMVs were as follows: Group 1, mean=647 mL (SD=310); Group 2, mean=520 mL (SD=298); and Group 3, mean=434 mL (SD=291). Results from one-way analysis of variance revealed significant differences in the mean MMV based on the method of maternal milk expression (p=0.0019). Further analysis using Tukey's HSD Test revealed significant differences in the MMV between Groups 1 and 3 (p < 0.01), but not between Groups 1 and 2 or between Groups 2 and 3. Electric breast pumps provided the highest mean MMV; however, many mothers obtained adequate feeding volumes for their infants' daily nutritional needs with the single non-electric manual breast pump and hand breastmilk expression.
BIG SKY CARBON SEQUESTRATION PARTNERSHIP
DOE Office of Scientific and Technical Information (OSTI.GOV)
Susan M. Capalbo
The Big Sky Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts during the second performance period fall into four areas: evaluation of sources and carbon sequestration sinks; development of GIS-based reporting framework; designing an integrated suite of monitoring, measuring, and verification technologies; and initiating a comprehensive education and outreach program. At the first two Partnership meetings the groundwork was put in place to provide an assessment of capture and storage capabilities for CO{sub 2} utilizing the resources foundmore » in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other western DOE partnerships. Efforts are also being made to find funding to include Wyoming in the coverage areas for both geological and terrestrial sinks and sources. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts begun in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is also underway to identify and validate best management practices for soil C in the partnership region, and to design a risk/cost effectiveness framework to make comparative assessments of each viable sink, taking into account economic costs, offsetting benefits, scale of sequestration opportunities, spatial and time dimensions, environmental risks, and long term viability. Scientifically sound information on MMV is critical for public acceptance of these technologies. Two key deliverables were completed this quarter--a literature review/database to assess the soil carbon on rangelands, and the draft protocols, contracting options for soil carbon trading. To date, there has been little research on soil carbon on rangelands, and since rangeland constitutes a major land use in the Big Sky region, this is important in achieving a better understanding of terrestrial sinks. The protocols developed for soil carbon trading are unique and provide a key component of the mechanisms that might be used to efficiently sequester GHG and reduce CO{sub 2} concentrations. Progress on other deliverables is noted in the PowerPoint presentations. A series of meetings held during the second quarter have laid the foundations for assessing the issues surrounding the implementation of a market-based setting for soil C credits. These meetings provide a connection to stakeholders in the region and a basis on which to draw for the DOE PEIS hearings. Finally, the education and outreach efforts have resulted in a comprehensive plan and process which serves as a guide for implementing the outreach activities under Phase I. While we are still working on the public website, we have made many presentations to stakeholders and policy makers, connections to other federal and state agencies concerned with GHG emissions, climate change, and efficient and environmentally-friendly energy production. In addition, we have laid plans for integration of our outreach efforts with the students, especially at the tribal colleges and at the universities involved in our partnership. This includes collaboration with the film and media arts departments at MSU, with outreach efforts at LANL, and with student section of the ASME. Finally, both Pam Tomski, outreach coordinator, and Susan Capalbo, PI for the Big Sky Partnership will be involved in future U.S.-Norway bilaterals in an effort to provide for an exchange of research and students/faculty.« less
Mitral valve replacement for mitral stenosis: A 15-year single center experience.
Al Mosa, Alqasem F; Omair, Aamir; Arifi, Ahmed A; Najm, Hani K
2016-10-01
Mitral valve replacement with either a bioprosthetic or a mechanical valve is the treatment of choice for severe mitral stenosis. However, choosing a valve implant type is still a subject of debate. This study aimed to evaluate and compare the early and late outcomes of mitral valve replacement [mechanical (MMV) vs. bioprosthetic (BMV)] for severe mitral stenosis. A retrospective cohort study was performed on data involving mitral stenosis patients who have undergone mitral valve replacement with either BMV (n = 50) or MMV (n = 145) valves from 1999 to 2012. Data were collected from the patients' records and follow-up through telephone calls. Data were analyzed for early and late mortality, New York Heart Association (NYHA) functional classes, stroke, pre- and postoperative echocardiographic findings, early and late valve-related complications, and survival. Chi-square test, logistic regression, Kaplan-Meier curve, and dependent proportions tests were some of the tests employed in the analysis. A total of 195 patients were included in the study with a 30-day follow-up echocardiogram available for 190 patients (97.5%), while 103 (53%) were available for follow-up over the telephone. One patient died early postoperatively; twelve patients died late in the postoperative period, six in the bioprosthesis group and six in the mechanical group. The late mortality had a significant association with postoperative stroke (p < 0.001) and postoperative NYHA Classes III and IV (p = 0.002). Postoperative NYHA class was significantly associated with age (p = 0.003), pulmonary disease (p = 0.02), mitral valve implant type (p = 0.01), and postoperative stroke (p = 0.02); 14 patients had strokes in the mechanical (9) and in the bioprosthetic (5) groups. NYHA classes were significantly better after the replacement surgeries (p < 0.001). BMV were significantly associated with worse survival (p = 0.03), worse NYHA postoperatively (p = 0.01), and more reoperations (p = 0.006). Survival was significantly better with MMV (p = 0.03). When the two groups were matched for age and mitral regurgitation, the analysis revealed that BMV were significantly associated with reoperations (p = 0.02) but not significantly associated with worse survival (p = 0.4) or worse NYHA (p = 0.4). MMV replacement in mitral stenosis patients is associated with a lower reoperation rate, but there was no difference in survival compared with BMV replacement.
First Report of Carnation vein mottle virus Infecting Dianthus amurensis in China
USDA-ARS?s Scientific Manuscript database
Tomato mottle mosaic virus (ToMMV), a tentative member in genus Tobamovirus, was first reported from a greenhouse tomato sample collected in Mexico in 2013 (1). In August 2013, foliar mottle, shrinking and necrosis were observed on pepper plants in several vegetable greenhouses of Lhasa, Tibet Auton...
Comparison of 7.0- and 3.0-T MRI and MRA in ischemic-type moyamoya disease: preliminary experience.
Deng, Xiaofeng; Zhang, Zihao; Zhang, Yan; Zhang, Dong; Wang, Rong; Ye, Xun; Xu, Long; Wang, Bo; Wang, Kai; Zhao, Jizong
2016-06-01
OBJECT The authors compared the image quality and diagnostic sensitivity and specificity of 7.0-T and 3.0-T MRI and time-of-flight (TOF) MR angiography (MRA) in patients with moyamoya disease (MMD). METHODS MR images of 15 patients with ischemic-type MMD (8 males, 7 females; age 13-48 years) and 13 healthy controls (7 males, 6 females; age 19-28 years) who underwent both 7.0-T and 3.0-T MRI and MRA were studied retrospectively. The main intracranial arteries were assessed by using the modified Houkin's grading system (MRA score). Moyamoya vessels (MMVs) were evaluated by 2 grading systems: the MMV quality score and the MMV area score. Two diagnostic criteria for MMD were used: the T2 criteria, which used flow voids in the basal ganglion on T2-weighted images, and the TOF criteria, which used the high-intensity areas in the basal ganglion on source images from TOF MRA. All data were evaluated by 2 independent readers who were blinded to the strength field and presence or absence of MMD. Using conventional angiography as the gold standard, the sensitivity and specificity of 7.0-T and 3.0-T MRI/MRA in the diagnosis of MMD were calculated. The differences between 7.0-T and 3.0-T MRI and MRA were statistically compared. RESULTS No significant differences were observed between 7.0-T and 3.0-T MRA in MRA score (p = 0.317) or MRA grade (p = 0.317). There was a strong correlation between the Suzuki's stage and MRA grade in both 3.0-T (rs = 0.930; p < 0.001) and 7.0-T (rs = 0.966; p < 0.001) MRA. However, MMVs were visualized significantly better on 7.0-T than on 3.0-T MRA, suggested by both the MMV quality score (p = 0.001) and the MMV area score (p = 0.001). The correlation between the Suzuki's stage and the MMV area score was moderate in 3.0-T MRA (rs = 0.738; p = 0.002) and strong in 7.0-T MRA (rs = 0.908; p < 0.001). Moreover, 7.0-T MR images showed a greater capacity for detecting flow voids in the basal ganglion on both T2-weighted MR images (p < 0.001) and TOF source images (p < 0.001); 7.0-T MRA also revealed the subbranches of superficial temporal arteries much better. Receiver operating characteristic curve analysis showed that, according to the T2 criteria, 7.0-T MRI/MRA was more sensitive (sensitivity 1.000; specificity 0.933) than 3.0-T MRI/MRA (sensitivity 0.692; specificity 0.933) in diagnosing MMD; based on the TOF criteria, 7.0-T MRI/MRA was more sensitive (1.000 vs 0.733, respectively) and more specific (1.000 vs 0.923, respectively) than 3.0-T MRI/MRA. CONCLUSIONS Compared with 3.0-T MRI/MRA, 7.0-T MRI/MRA detected and delineated MMVs more clearly and provided higher diagnostic sensitivity and specificity, although it did not show significant improvement in depicting main intracranial arteries. The authors speculate that 7.0-T MRI/MRA is a promising technique in the diagnosis of MMD because it is noninvasive compared with conventional angiography and it is more sensitive than 3.0-T MRI/MRA.
Martin, Kathleen M; Barandoc-Alviar, Karen; Schneweis, Derek J; Stewart, Catherine L; Rotenberg, Dorith; Whitfield, Anna E
2017-09-01
Maize mosaic virus (MMV) is a plant-pathogenic rhabdovirus that is transmitted by the corn planthopper, Peregrinus maidis, in a propagative manner. P. maidis supports long-term MMV infections with no negative effects on insect performance. To elucidate whole-body transcriptome responses to virus infection, RNA-Seq was used to examine differential gene expression of virus-infected adult insects, and libraries were prepared from replicated groups of virus-exposed insects and non-exposed insects. From the 68,003 de novo-assembled transcripts, 144 were differentially-expressed (DE) during viral infection with comparable numbers up- and down-regulated. DE transcripts with similarity to genes associated with transposable elements (i.e., RNA-directed DNA polymerases) were enriched and may represent a mechanisim for modulating virus infection. Comparison of the P. maidis DE transcripts to published propagative virus-responsive transcript databases for two other hopper vectors revealed that 16% of the DE transcripts were shared across the three systems and may represent conserved responses to propagative viruses. Copyright © 2017 Elsevier Inc. All rights reserved.
Whitfield, A E; Rotenberg, D; Aritua, V; Hogenhout, S A
2011-04-01
The corn planthopper, Peregrinus maidis, causes direct feeding damage to plants and transmits Maize mosaic rhabdovirus (MMV) in a persistent-propagative manner. MMV must cross several insect tissue layers for successful transmission to occur, and the gut serves as an important barrier for rhabdovirus transmission. In order to facilitate the identification of proteins that may interact with MMV either by facilitating acquisition or responding to virus infection, we generated and analysed the gut transcriptome of P. maidis. From two normalized cDNA libraries, we generated a P. maidis gut transcriptome composed of 20,771 expressed sequence tags (ESTs). Assembly of the sequences yielded 1860 contigs and 14,032 singletons, and biological roles were assigned to 5793 (36%). Comparison of P. maidis ESTs with other insect amino acid sequences revealed that P. maidis shares greatest sequence similarity with another hemipteran, the brown planthopper Nilaparvata lugens. We identified 202 P. maidis transcripts with putative homology to proteins associated with insect innate immunity, including those implicated in the Toll, Imd, JAK/STAT, Jnk and the small-interfering RNA-mediated pathways. Sequence comparisons between our P. maidis gut EST collection and the currently available National Center for Biotechnology Information EST database collection for Ni. lugens revealed that a pathogen recognition receptor in the Imd pathway, peptidoglycan recognition protein-long class (PGRP-LC), is present in these two members of the family Delphacidae; however, these recognition receptors are lacking in the model hemipteran Acyrthosiphon pisum. In addition, we identified sequences in the P. maidis gut transcriptome that share significant amino acid sequence similarities with the rhabdovirus receptor molecule, acetylcholine receptor (AChR), found in other hosts. This EST analysis sheds new light on immune response pathways in hemipteran guts that will be useful for further dissecting innate defence response pathways to rhabdovirus infection. © 2011 The Authors. Insect Molecular Biology © 2011 The Royal Entomological Society.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sacuta, Norm; Young, Aleana; Worth, Kyle
2015-12-22
The IEAGHG Weyburn-Midale CO₂ Monitoring and Storage Project (WMP) began in 2000 with the first four years of research that confirmed the suitability of the containment complex of the Weyburn oil field in southeastern Saskatchewan as a storage location for CO₂ injected as part of enhanced oil recovery (EOR) operations. The first half of this report covers research conducted from 2010 to 2012, under the funding of the United States Department of Energy (contract DEFE0002697), the Government of Canada, and various other governmental and industry sponsors. The work includes more in-depth analysis of various components of a measurement, monitoring andmore » verification (MMV) program through investigation of data on site characterization and geological integrity, wellbore integrity, storage monitoring (geophysical and geochemical), and performance/risk assessment. These results then led to the development of a Best Practices Manual (BPM) providing oilfield and project operators with guidance on CO₂ storage and CO₂-EOR. In 2013, the USDOE and Government of Saskatchewan exercised an optional phase of the same project to further develop and deploy applied research tools, technologies, and methodologies to the data and research at Weyburn with the aim of assisting regulators and operators in transitioning CO₂-EOR operations into permanent storage. This work, detailed in the second half of this report, involves seven targeted research projects – evaluating the minimum dataset for confirming secure storage; additional overburden monitoring; passive seismic monitoring; history-matched modelling; developing proper wellbore design; casing corrosion evaluation; and assessment of post CO₂-injected core samples. The results from the final and optional phases of the Weyburn-Midale Project confirm the suitability of CO₂-EOR fields for the injection of CO₂, and further, highlight the necessary MMV and follow-up monitoring required for these operations to be considered permanent storage.« less
USDA-ARS?s Scientific Manuscript database
Since its first discovery in 2013 in Mexico, Tomato mottle mosaic virus (ToMMV), a new tomato-infecting tobamovirus is now present in a number of countries (i.e., Brazil, China, and Israel) and several states in the U.S. There is little information available on the molecular and biological properti...
BIG SKY CARBON SEQUESTRATION PARTNERSHIP
DOE Office of Scientific and Technical Information (OSTI.GOV)
Susan M. Capalbo
2004-10-31
The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership fall into four areas: evaluation of sources and carbon sequestration sinks; development of GIS-based reporting framework; designing an integrated suite of monitoring, measuring, and verification technologies; and initiating a comprehensive education and outreach program. At the first two Partnership meetings the groundwork was put in place to provide an assessment of capture and storage capabilities for CO{sub 2} utilizing the resources foundmore » in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research. During the third quarter, planning efforts are underway for the next Partnership meeting which will showcase the architecture of the GIS framework and initial results for sources and sinks, discuss the methods and analysis underway for assessing geological and terrestrial sequestration potentials. The meeting will conclude with an ASME workshop. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other western DOE partnerships. Efforts are also being made to find funding to include Wyoming in the coverage areas for both geological and terrestrial sinks and sources. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts begun in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is also underway to identify and validate best management practices for soil C in the Partnership region, and to design a risk/cost effectiveness framework to make comparative assessments of each viable sink, taking into account economic costs, offsetting benefits, scale of sequestration opportunities, spatial and time dimensions, environmental risks, and long-term viability. Scientifically sound information on MMV is critical for public acceptance of these technologies. Two key deliverables were completed in the second quarter--a literature review/database to assess the soil carbon on rangelands, and the draft protocols, contracting options for soil carbon trading. The protocols developed for soil carbon trading are unique and provide a key component of the mechanisms that might be used to efficiently sequester GHG and reduce CO{sub 2} concentrations. While no key deliverables were due during the third quarter, progress on other deliverables is noted in the PowerPoint presentations and in this report. A series of meetings held during the second and third quarters have laid the foundations for assessing the issues surrounding carbon sequestration in this region, the need for a holistic approach to meeting energy demands and economic development potential, and the implementation of government programs or a market-based setting for soil C credits. These meetings provide a connection to stakeholders in the region and a basis on which to draw for the DOE PEIS hearings. In the fourth quarter, three deliverables have been completed, some in draft form to be revised and updated to include Wyoming. This is due primarily to some delays in funding to LANL and INEEL and the approval of a supplemental proposal to include Wyoming in much of the GIS data sets, analysis, and related materials. The deliverables are discussed in the following sections and greater details are provided in the materials that are attached to this report. In August 2004, a presentation was made to Pioneer Hi-Bred, discussing the Partnership and the synergies with terrestrial sequestration, agricultural industries, and ongoing, complimentary USDA efforts. The Partnership organized a Carbon session at the INRA 2004 Environmental and Subsurface Science Symposium in September 2004; also in September, a presentation was made to the Wyoming Carbon Sequestration Advisory Committee, followed up with a roundtable discussion.« less
Improving M-SBL for Joint Sparse Recovery Using a Subspace Penalty
NASA Astrophysics Data System (ADS)
Ye, Jong Chul; Kim, Jong Min; Bresler, Yoram
2015-12-01
The multiple measurement vector problem (MMV) is a generalization of the compressed sensing problem that addresses the recovery of a set of jointly sparse signal vectors. One of the important contributions of this paper is to reveal that the seemingly least related state-of-art MMV joint sparse recovery algorithms - M-SBL (multiple sparse Bayesian learning) and subspace-based hybrid greedy algorithms - have a very important link. More specifically, we show that replacing the $\\log\\det(\\cdot)$ term in M-SBL by a rank proxy that exploits the spark reduction property discovered in subspace-based joint sparse recovery algorithms, provides significant improvements. In particular, if we use the Schatten-$p$ quasi-norm as the corresponding rank proxy, the global minimiser of the proposed algorithm becomes identical to the true solution as $p \\rightarrow 0$. Furthermore, under the same regularity conditions, we show that the convergence to a local minimiser is guaranteed using an alternating minimization algorithm that has closed form expressions for each of the minimization steps, which are convex. Numerical simulations under a variety of scenarios in terms of SNR, and condition number of the signal amplitude matrix demonstrate that the proposed algorithm consistently outperforms M-SBL and other state-of-the art algorithms.
Big Sky Carbon Sequestration Partnership
DOE Office of Scientific and Technical Information (OSTI.GOV)
Susan M. Capalbo
2005-11-01
The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership in Phase I fall into four areas: evaluation of sources and carbon sequestration sinks that will be used to determine the location of pilot demonstrations in Phase II; development of GIS-based reporting framework that links with national networks; designing an integrated suite of monitoring, measuring, and verification technologies and assessment frameworks; and initiating a comprehensive education and outreach program. The groundwork ismore » in place to provide an assessment of storage capabilities for CO2 utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research agenda in Carbon Sequestration. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other DOE regional partnerships. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is also underway to identify and validate best management practices for soil C in the Partnership region, and to design a risk/cost effectiveness framework to make comparative assessments of each viable sink, taking into account economic costs, offsetting benefits, scale of sequestration opportunities, spatial and time dimensions, environmental risks, and long-term viability. Scientifically sound MMV is critical for public acceptance of these technologies. Deliverables for the 7th Quarter reporting period include (1) for the geological efforts: Reports on Technology Needs and Action Plan on the Evaluation of Geological Sinks and Pilot Project Deployment (Deliverables 2 and 3), and Report on the Feasibility of Mineralization Trapping in the Snake River Plain Basin (Deliverable 14); (2) for the terrestrial efforts: Report on the Evaluation of Terrestrial Sinks and a Report of the Best Production Practices for Soil C Sequestration (Deliverables 8 and 15). In addition, the 7th Quarter activities for the Partnership included further development of the proposed activities for the deployment and demonstration phase of the carbon sequestration pilots including geological and terrestrial pilots, expansion of the Partnership to encompass regions and institutions that are complimentary to the steps we have identified, building greater collaborations with industry and stakeholders in the region, contributed to outreach efforts that spanned all partnerships, co-authorship on the Carbon Capture and Separation report, and developed a regional basis to address future energy opportunities in the region. The deliverables and activities are discussed in the following sections and appended to this report. The education and outreach efforts have resulted in a comprehensive plan which serves as a guide for implementing the outreach activities under Phase I. The public website has been expanded and integrated with the GIS carbon atlas. We have made presentations to stakeholders and policy makers including two tribal sequestration workshops, and made connections to other federal and state agencies concerned with GHG emissions, climate change, and efficient and environmentally-friendly energy production. In addition, the Partnership has plans for integration of our outreach efforts with students, especially at the tribal colleges and at the universities involved in our Partnership. This includes collaboration with MSU and with the U.S.-Norway Summer School, extended outreach efforts at LANL and INEEL, and with the student section of the ASME. Finally, the Big Sky Partnership was involved in key meetings and symposium in the 7th quarter including the USDOE Wye Institute Conference on Carbon Sequestration and Capture (April, 2005); the DOE/NETL Fourth Annual Conference on Carbon Capture and Sequestration (May 2005); Coal Power Development Conference (Denver, June 2005) and meetings with our Phase II industry partners and Governor's staff.« less
Kipandula, Wakisa; Young, Simon A; MacNeill, Stuart A; Smith, Terry K
2018-06-01
Diseases caused by the pathogenic kinetoplastids continue to incapacitate and kill hundreds of thousands of people annually throughout the tropics and sub-tropics. Unfortunately, in the countries where these neglected diseases occur, financial obstacles to drug discovery and technical limitations associated with biochemical studies impede the development of new, safe, easy to administer and effective drugs. Here we report the development and optimisation of a Crithidia fasciculata resazurin viability assay, which is subsequently used for screening and identification of anti-crithidial compounds in the MMV and GSK open access chemical boxes. The screening assay had an average Z' factor of 0.7 and tolerated a maximum dimethyl sulfoxide concentration of up to 0.5%. We identified from multiple chemical boxes two compound series exhibiting nanomolar potency against C. fasciculata, one centred around a 5-nitrofuran-2-yl scaffold, a well-known moiety in several existing anti-infectives, and another involving a 2-(pyridin-2-yl) pyrimidin-4-amine scaffold which seems to have pan-kinetoplastid activity. This work facilitates the future use of C. fasciculata as a non-pathogenic and inexpensive biological resource to identify mode of action/protein target(s) of potentially pan-trypanocidal potent compounds. This knowledge will aid in the development of new treatments for African sleeping sickness, Chagas disease and leishmaniasis. Copyright © 2018 Elsevier B.V. All rights reserved.
Kraft, Thomas E; Heitmeier, Monique R; Putanko, Marina; Edwards, Rachel L; Ilagan, Ma Xenia G; Payne, Maria A; Autry, Joseph M; Thomas, David D; Odom, Audrey R; Hruz, Paul W
2016-12-01
The glucose transporter PfHT is essential to the survival of the malaria parasite Plasmodium falciparum and has been shown to be a druggable target with high potential for pharmacological intervention. Identification of compounds against novel drug targets is crucial to combating resistance against current therapeutics. Here, we describe the development of a cell-based assay system readily adaptable to high-throughput screening that directly measures compound effects on PfHT-mediated glucose transport. Intracellular glucose concentrations are detected using a genetically encoded fluorescence resonance energy transfer (FRET)-based glucose sensor. This allows assessment of the ability of small molecules to inhibit glucose uptake with high accuracy (Z' factor of >0.8), thereby eliminating the need for radiolabeled substrates. Furthermore, we have adapted this assay to counterscreen PfHT hits against the human orthologues GLUT1, -2, -3, and -4. We report the identification of several hits after screening the Medicines for Malaria Venture (MMV) Malaria Box, a library of 400 compounds known to inhibit erythrocytic development of P. falciparum Hit compounds were characterized by determining the half-maximal inhibitory concentration (IC 50 ) for the uptake of radiolabeled glucose into isolated P. falciparum parasites. One of our hits, compound MMV009085, shows high potency and orthologue selectivity, thereby successfully validating our assay for antimalarial screening. Copyright © 2016, American Society for Microbiology. All Rights Reserved.
Brunschwig, Christel; Lawrence, Nina; Taylor, Dale; Abay, Efrem; Njoroge, Mathew; Basarab, Gregory S; Le Manach, Claire; Paquet, Tanya; Gonzàlez Cabrera, Diego; Nchinda, Aloysius T; de Kock, Carmen; Wiesner, Lubbe; Denti, Paolo; Waterson, David; Blasco, Benjamin; Leroy, Didier; Witty, Michael J; Donini, Cristina; Duffy, James; Wittlin, Sergio; White, Karen L; Charman, Susan A; Jiménez-Díaz, Maria Belén; Angulo-Barturen, Iñigo; Herreros, Esperanza; Gamo, Francisco Javier; Rochford, Rosemary; Mancama, Dalu; Coetzer, Theresa L; van der Watt, Mariëtte E; Reader, Janette; Birkholtz, Lyn-Marie; Marsh, Kennan C; Solapure, Suresh M; Vanaerschot, Manu; Fidock, David A; Fish, Paul V; Siegl, Peter; Smith, Dennis A; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N; Marfurt, Jutta; Silue, Kigbafori D; Street, Leslie J; Chibale, Kelly
2018-06-25
The 2-aminopyridine MMV048 was the first drug candidate inhibiting Plasmodium phosphatidylinositol 4-kinase (PI4K), a novel drug target for malaria, to enter clinical development. In an effort to identify the next generation of PI4K inhibitors, the series was optimized to improve properties such as solubility and antiplasmodial potency across the parasite lifecycle, leading to the 2-aminopyrazine UCT943. The compound displayed higher asexual blood stage, transmission-blocking, and liver stage activity than MMV048 and was more potent against resistant P. falciparum and P. vivax clinical isolates. Excellent in vitro antiplasmodial activity translated into high efficacy in P. berghei and humanized P. falciparum NOD- scid IL-2Rγ null mouse models. The high passive permeability and high aqueous solubility of UCT943, combined with low to moderate in vitro intrinsic clearance, resulted in sustained exposure and high bioavailability in preclinical species. In addition, the predicted human dose for a curative single administration using monkey and dog pharmacokinetics was low, ranging from 50 to 80 mg. As a next generation Plasmodium PI4K inhibitor, the combined preclinical data suggest that UCT943 has the potential to form part of a single-exposure radical cure and prophylaxis (SERCaP) to treat, prevent and block the transmission of malaria. Copyright © 2018 American Society for Microbiology.
An Investigation of Certain Thermodynamic Losses in Miniature Cryocoolers
2007-05-02
system Channel Measurement Parameter Sensor Gain Offset 1 Pressure in Volume A Endevco 2.408 bar/V 6.0206 bar 2 Pressure in Volume C Druck 200...1.9677 bar/V 15.444 bar 3 N/C 4 Pressure in compressor body Druck 820 6.0046 bar/V 8.3174 bar 5 Piston Position Sch’ LVDT 2.0884 mm/V -5.5968 mm...probe (courtesy of Prof. Moriyoshi). Left: 3D view showing two fine thermocouples are in a cross configuration. Right: Side elevation Results
Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways
Allman, Erik L.; Painter, Heather J.; Samra, Jasmeet; Carrasquilla, Manuela
2016-01-01
The threat of widespread drug resistance to frontline antimalarials has renewed the urgency for identifying inexpensive chemotherapeutic compounds that are effective against Plasmodium falciparum, the parasite species responsible for the greatest number of malaria-related deaths worldwide. To aid in the fight against malaria, a recent extensive screening campaign has generated thousands of lead compounds with low micromolar activity against blood stage parasites. A subset of these leads has been compiled by the Medicines for Malaria Venture (MMV) into a collection of structurally diverse compounds known as the MMV Malaria Box. Currently, little is known regarding the activity of these Malaria Box compounds on parasite metabolism during intraerythrocytic development, and a majority of the targets for these drugs have yet to be defined. Here we interrogated the in vitro metabolic effects of 189 drugs (including 169 of the drug-like compounds from the Malaria Box) using ultra-high-performance liquid chromatography–mass spectrometry (UHPLC-MS). The resulting metabolic fingerprints provide information on the parasite biochemical pathways affected by pharmacologic intervention and offer a critical blueprint for selecting and advancing lead compounds as next-generation antimalarial drugs. Our results reveal several major classes of metabolic disruption, which allow us to predict the mode of action (MoA) for many of the Malaria Box compounds. We anticipate that future combination therapies will be greatly informed by these results, allowing for the selection of appropriate drug combinations that simultaneously target multiple metabolic pathways, with the aim of eliminating malaria and forestalling the expansion of drug-resistant parasites in the field. PMID:27572391
Penicillinase-based enzyme-linked immunosorbent assay for the detection of plant viruses.
Sudarshana, M R; Reddy, D V
1989-10-01
A penicillinase (PNC)-based, enzyme-linked immunosorbent assay (ELISA) was standardized to detect maize mosaic virus (MMV) in sorghum leaf extracts, peanut mottle virus (PMV) in pea leaf extracts, and tomato spotted wilt virus (TSWV) in peanut leaf extracts. Rabbit Fc-specific antibodies were conjugated with PNC by a single step glutaraldehyde bridge. Among several indicators tested, bromothymol blue (BTB) was found suitable for measuring PNC activity under simulated conditions. Two reagents, starch-iodine complex (SIC) and a mixed pH indicator, containing bromocresol purple and BTB (2:1) used earlier for the PNC-based ELISA, were compared with BTB for utilization in the PNC-based ELISA. SIC gave a slightly higher virus titre than BTB or the mixed pH indicator, but it often gave nonspecific reactions. Sodium or potassium salts of penicillin-G at 0.5-1.0 mg/ml and BTB at 0.2 mg/ml were found to be suitable as substrate-indicator mixture for PNC-based ELISA. The sensitivity of the PNC system was comparable to those of the alkaline phosphatase (ALP) and horseradish peroxidase (HRP) systems in detecting MMV, PMV, and TSWV. The PNC conjugate could be used at a greater dilution than those of the ALP and HRP conjugates and the BTB substrate mixture was stable for at least 3 weeks at 4 degrees C. Penicillin is readily available in developing countries, and at a substantially lower cost than p-nitrophenyl phosphate, the commonly used substrate for ALP in the plate ELISA. Thus the PNC-based ELISA provides a less expensive means for assaying plant viruses by ELISA.
Murphy, Marie; Quesada, Guillermo Miro; Chen, Dayue
2011-11-01
Viral contamination of mammalian cell cultures in GMP manufacturing facility represents a serious safety threat to biopharmaceutical industry. Such adverse events usually require facility shutdown for cleaning/decontamination, and thus result in significant loss of production and/or delay of product development. High temperature short time (HTST) treatment of culture media has been considered as an effective method to protect GMP facilities from viral contaminations. Log reduction factor (LRF) has been commonly used to measure the effectiveness of HTST treatment for viral inactivation. However, in order to prevent viral contaminations, HTST treatment must inactivate all infectious viruses (100%) in the medium batch since a single virus is sufficient to cause contamination. Therefore, LRF may not be the most appropriate indicator for measuring the effectiveness of HTST in preventing viral contaminations. We report here the use of the probability to achieve complete (100%) virus inactivation to assess the effectiveness of HTST treatment. By using mouse minute virus (MMV) as a model virus, we have demonstrated that the effectiveness of HTST treatment highly depends upon the level of viral contaminants in addition to treatment temperature and duration. We believe that the statistical method described in this report can provide more accurate information about the power and potential limitation of technologies such as HTST in our shared quest to mitigate the risk of viral contamination in manufacturing facilities. Copyright © 2011 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.
United States Automotive Materials Partnership LLC (USAMP)
DOE Office of Scientific and Technical Information (OSTI.GOV)
United States Automotive Materials Partnership
2011-01-31
The United States Automotive Materials Partnership LLC (USAMP) was formed in 1993 as a partnership between Chrysler Corporation, Ford Motor Company, and General Motors Corporation. Since then the U.S. Department of Energy (DOE) has supported its activities with funding and technical support. The mission of the USAMP is to conduct vehicle-oriented research and development in materials and materials processing to improve the competitiveness of the U.S. Auto Industry. Its specific goals are: (1) To conduct joint research to further the development of lightweight materials for improved automotive fuel economy; and (2) To work with the Federal government to explore opportunitiesmore » for cooperative programs with the national laboratories, Federal agencies such as the DOE and universities. As a major component of the DOE's Office of FreedomCAR and Vehicle Technologies Program (FCVT) collaboration with the USAMP, the Automotive Lightweighting Materials (ALM) program focuses on the development and validation of advanced materials and manufacturing technologies to significantly reduce automotive vehicle body and chassis weight without compromising other attributes such as safety, performance, recyclability, and cost. The FCVT was announced in FY 2002 and implemented in FY 2003, as a successor of the Partnership for a New Generation of Vehicles (PNGV), largely addressed under the first Cooperative Agreement. This second USAMP Cooperative Agreement with the DOE has expanded a unique and valuable framework for collaboratively directing industry and government research efforts toward the development of technologies capable of solving important societal problems related to automobile transportation. USAMP efforts are conducted by the domestic automobile manufacturers, in collaboration with materials and manufacturing suppliers, national laboratories, universities, and other technology or trade organizations. These interactions provide a direct route for implementing newly developed materials and technologies, and have resulted in significant technical successes to date, as discussed in the individual project summary final reports. Over 70 materials-focused projects have been established by USAMP, in collaboration with participating suppliers, academic/non-profit organizations and national laboratories, and executed through its original three divisions: the Automotive Composites Consortium (ACC), the Automotive Metals Division (AMD), and Auto/Steel Partnership (A/SP). Two new divisions were formed by USAMP in 2006 to drive research emphasis on integration of structures incorporating dissimilar lightweighting materials, and on enabling technology for nondestructive evaluation of structures and joints. These new USAMP divisions are: Multi-Material Vehicle Research and Development Initiative (MMV), and the Non-Destructive Evaluation Steering Committee (NDE). In cooperation with USAMP and the FreedomCAR Materials Technical Team, a consensus process has been established to facilitate the development of projects to help move leveraged research to targeted development projects that eventually migrate to the original equipment manufacturers (OEMs) as application engineering projects. Research projects are assigned to one of three phases: concept feasibility, technical feasibility, and demonstration feasibility. Projects are guided through ongoing monitoring and USAMP offsite reviews, so as to meet the requirements of each phase before they are allowed to move on to the next phase. As progress is made on these projects, the benefits of lightweight construction and enabling technologies will be transferred to the supply base and implemented in production vehicles. The single greatest barrier to automotive use of lightweight materials is their high cost; therefore, priority is given to activities aimed at reducing costs through development of new materials, forming technologies, and manufacturing processes. The emphasis of the research projects reported in this document was largely on applied research and evaluation of mass savings opportunities through the aggressive application of lightweight materials, advanced computational methods, and the demonstration of production capable manufacturing processes intended for high-volume applications, all directed towards the FreedomCAR Program goals. Priority lightweighting materials include advanced high-strength steels (AHSS), aluminum, magnesium, titanium, and composites such as metal-matrix materials, and glass- and carbon-fiber-reinforced thermosets and thermoplastics. Besides developing valuable new design and material property information, several projects have extensively used computer-based product modeling and simulation technologies to optimize designs and materials usage while addressing the cost-performance issues. The purpose of this Summary Final Closeout Report is to document the successes, degree of progress, technology dissemination efforts, and lessons learned.« less
Geochemical Modeling of Carbon Sequestration, MMV, and EOR in the Illinois Basin
Berger, P.M.; Roy, W.R.; Mehnert, E.
2009-01-01
The Illinois State Geologic Survey is conducting several ongoing CO2 sequestration projects that require geochemical models to gain an understanding of the processes occurring in the subsurface. The ISGS has collected brine and freshwater samples associated with an enhanced oil recovery project in the Loudon oil field. Geochemical modeling allows us to understand reactions with carbonate and silicate minerals in the reservoir, and the effects they have had on brine composition. For the Illinois Basin Decatur project, geochemical models should allow predictions of the reactions that will take place before CO2 injection begins. ?? 2009 Elsevier Ltd. All rights reserved.
[Development and Distribution of Drugs for NTDs: Efforts of One Pharmaceutical Company].
Asada, Makoto
2016-01-01
The Pharmaceutical Industry is expected to play a proactive global role in combatting neglected tropical diseases (NTDs) and other tropical diseases affecting low-income countries. Such a role would include novel medicine R&D, manufacturing and distribution. In order to succeed in this role, several challenges need to be overcome: a) the economic challenge or cost benefit balance for the development of these medicines, and b) sparse in-house experience with these diseases within the Industry. During the last decade, the Product Development Partnership (PDP) model has become an effective strategy to address such challenges. Organizations such as the Medicines for Malaria Venture (MMV), Drugs for Neglected Diseases initiative (DNDi), TB alliance, PATH (formerly the Program for Appropriate Technology in Health), and others have linked pharmaceutical companies, funding organizations, academic researchers and others, and have thus been able to successfully populate treatment pipelines directed at NTDs, Malaria, tuberculosis (TB), and human immunodeficiency virus (HIV)/AIDS. In this paper, our experience working with one of these organizations, DNDi, is described. We have been collaborating with DNDi in evaluating the actions of Eisai's antifungal compound, E1224, in a clinical study for treating Chagas Disease. In addition, other Eisai initiatives directed at NTDs and improving patients' access to medicines are introduced.
Development of RNAi methods for Peregrinus maidis, the corn planthopper.
Yao, Jianxiu; Rotenberg, Dorith; Afsharifar, Alireza; Barandoc-Alviar, Karen; Whitfield, Anna E
2013-01-01
The corn planthopper, Peregrinus maidis, is a major pest of agronomically-important crops. Peregrinus maidis has a large geographical distribution and transmits Maize mosaic rhabdovirus (MMV) and Maize stripe tenuivirus (MSpV). The objective of this study was to develop effective RNAi methods for P. maidis. Vacuolar-ATPase (V-ATPase) is an essential enzyme for hydrolysis of ATP and for transport of protons out of cells thereby maintaining membrane ion balance, and it has been demonstrated to be an efficacious target for RNAi in other insects. In this study, two genes encoding subunits of P. maidis V-ATPase (V-ATPase B and V-ATPase D) were chosen as RNAi target genes. The open reading frames of V-ATPase B and D were generated and used for constructing dsRNA fragments. Experiments were conducted using oral delivery and microinjection of V-ATPase B and V-ATPase D dsRNA to investigate the effectiveness of RNAi in P. maidis. Real-time quantitative reverse transcriptase-PCR (qRT-PCR) analysis indicated that microinjection of V-ATPase dsRNA led to a minimum reduction of 27-fold in the normalized abundance of V-ATPase transcripts two days post injection, while ingestion of dsRNA resulted in a two-fold reduction after six days of feeding. While both methods of dsRNA delivery resulted in knockdown of target transcripts, the injection method was more rapid and effective. The reduction in V-ATPase transcript abundance resulted in observable phenotypes. Specifically, the development of nymphs injected with 200 ng of either V-ATPase B or D dsRNA was impaired, resulting in higher mortality and lower fecundity than control insects injected with GFP dsRNA. Microscopic examination of these insects revealed that female reproductive organs did not develop normally. The successful development of RNAi in P. maidis to target specific genes will enable the development of new insect control strategies and functional analysis of vital genes and genes associated with interactions between P. maidis and MMV.
The pharmaceutical death-ride of dihydroartemisinin
2010-01-01
In the 2010 second edition of WHO's guidelines for the treatment of malaria, the relatively new fixed dose combination dihydroartemisinin-piperaquine is included as one of the recommended artemisinin combination therapies. However, experimental testing demonstrates that, due to its intrinsic chemical instability, dihydroartemisinin is not suitable to be used in pharmaceutical formulations. In addition, data show that the currently available dihydroartemisinin preparations fail to meet the internationally accepted stability requirements. At a time when many efforts aim to ban counterfeit and substandard drugs from the malaria market, the obvious question rises how WHO and public-private partnerships, such as Medicine for Malaria venture (MMV), can support the production and marketing of anti-malarial drugs that do not even meet the International Pharmacopoeia requirements? PMID:20649950
Kui, Ling; Chen, Haitao; Zhang, Weixiong; He, Simei; Xiong, Zijun; Zhang, Yesheng; Yan, Liang; Zhong, Chaofang; He, Fengmei; Chen, Junwen; Zeng, Peng; Zhang, Guanghui; Yang, Shengchao; Dong, Yang; Wang, Wen; Cai, Jing
2017-01-01
Orchidaceae is the second largest family of flowering plants, which is highly valued for its ornamental purposes and medicinal uses. Dendrobium officinale is a special orchid species that can grow without seed vernalization. Because the whole-genome sequence of D. officinale is publicly available, this species is poised to become a convenient research model for the evolutionary, developmental, and genetic studies of Orchidaceae. Despite these advantages, the methods of genetic manipulation are poorly developed in D. officinale. In this study, based on the previously developed Agrobacterium-mediated gene transformation system, we identified several highly efficient promoters for exogenous gene expression and successfully applied the CRISPR/Cas9 system for editing endogenous genes in the genome of D. officinale. These two basic techniques contribute to the genetic manipulation toolbox of Orchidaceae. The pCambia-1301-35SN vector containing the CaMV 35S promoter and the β-glucuronidase (GUS) and Superfolder green fluorescence protein (SG) as reporter genes were introduced into the plant tissues by the Agrobacterium-mediated transformation system. Fluorescence emission from the transformed plants confirmed the successful transcription and translation of SG genes into functional proteins. We compared the GUS activity under different promoters including four commonly used promoters (MtHP, CVMV, MMV and PCISV) with CaMV 35S promoter and found that MMV, CVMV, and PCISV were as effective as the 35S promoter. Furthermore, we applied the CRISPR/Cas9-mediated genome editing system successfully in D. officinale. By selecting five target genes (C3H, C4H, 4CL, CCR, and IRX) in the lignocellulose biosynthesis pathway, we showed that, for a given target, this system can generate edits (insertions, deletions, or substitutions) at a rate of 10 to 100%. These results showed that our two genetic manipulation tools can efficiently express exogenous genes and edit endogenous genes in D. officinale. These efficient research tools will not only help create novel D. officinale varieties, but will also facilitate the molecular genetic investigation of orchid biology. PMID:28127299
Kui, Ling; Chen, Haitao; Zhang, Weixiong; He, Simei; Xiong, Zijun; Zhang, Yesheng; Yan, Liang; Zhong, Chaofang; He, Fengmei; Chen, Junwen; Zeng, Peng; Zhang, Guanghui; Yang, Shengchao; Dong, Yang; Wang, Wen; Cai, Jing
2016-01-01
Orchidaceae is the second largest family of flowering plants, which is highly valued for its ornamental purposes and medicinal uses. Dendrobium officinale is a special orchid species that can grow without seed vernalization. Because the whole-genome sequence of D. officinale is publicly available, this species is poised to become a convenient research model for the evolutionary, developmental, and genetic studies of Orchidaceae. Despite these advantages, the methods of genetic manipulation are poorly developed in D. officinale . In this study, based on the previously developed Agrobacterium -mediated gene transformation system, we identified several highly efficient promoters for exogenous gene expression and successfully applied the CRISPR/Cas9 system for editing endogenous genes in the genome of D. officinale . These two basic techniques contribute to the genetic manipulation toolbox of Orchidaceae. The pCambia-1301-35SN vector containing the CaMV 35S promoter and the β-glucuronidase ( GUS ) and Superfolder green fluorescence protein (SG) as reporter genes were introduced into the plant tissues by the Agrobacterium -mediated transformation system. Fluorescence emission from the transformed plants confirmed the successful transcription and translation of SG genes into functional proteins. We compared the GUS activity under different promoters including four commonly used promoters (MtHP, CVMV, MMV and PCISV) with CaMV 35S promoter and found that MMV, CVMV, and PCISV were as effective as the 35S promoter. Furthermore, we applied the CRISPR/Cas9-mediated genome editing system successfully in D. officinale . By selecting five target genes ( C3H, C4H, 4CL, CCR, and IRX ) in the lignocellulose biosynthesis pathway, we showed that, for a given target, this system can generate edits (insertions, deletions, or substitutions) at a rate of 10 to 100%. These results showed that our two genetic manipulation tools can efficiently express exogenous genes and edit endogenous genes in D. officinale . These efficient research tools will not only help create novel D. officinale varieties, but will also facilitate the molecular genetic investigation of orchid biology.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brian McPherson
The Southwest Partnership on Carbon Sequestration completed its Phase I program in December 2005. The main objective of the Southwest Partnership Phase I project was to evaluate and demonstrate the means for achieving an 18% reduction in carbon intensity by 2012. Many other goals were accomplished on the way to this objective, including (1) analysis of CO{sub 2} storage options in the region, including characterization of storage capacities and transportation options, (2) analysis and summary of CO{sub 2} sources, (3) analysis and summary of CO{sub 2} separation and capture technologies employed in the region, (4) evaluation and ranking of themore » most appropriate sequestration technologies for capture and storage of CO{sub 2} in the Southwest Region, (5) dissemination of existing regulatory/permitting requirements, and (6) assessing and initiating public knowledge and acceptance of possible sequestration approaches. Results of the Southwest Partnership's Phase I evaluation suggested that the most convenient and practical ''first opportunities'' for sequestration would lie along existing CO{sub 2} pipelines in the region. Action plans for six Phase II validation tests in the region were developed, with a portfolio that includes four geologic pilot tests distributed among Utah, New Mexico, and Texas. The Partnership will also conduct a regional terrestrial sequestration pilot program focusing on improved terrestrial MMV methods and reporting approaches specific for the Southwest region. The sixth and final validation test consists of a local-scale terrestrial pilot involving restoration of riparian lands for sequestration purposes. The validation test will use desalinated waters produced from one of the geologic pilot tests. The Southwest Regional Partnership comprises a large, diverse group of expert organizations and individuals specializing in carbon sequestration science and engineering, as well as public policy and outreach. These partners include 21 state government agencies and universities, five major electric utility companies, seven oil, gas and coal companies, three federal agencies, the Navajo Nation, several NGOs, and the Western Governors Association. This group is continuing its work in the Phase II Validation Program, slated to conclude in 2009.« less
Weaning from mechanical ventilation: why are we still looking for alternative methods?
Frutos-Vivar, F; Esteban, A
2013-12-01
Most patients who require mechanical ventilation for longer than 24 hours, and who improve the condition leading to the indication of ventilatory support, can be weaned after passing a first spontaneous breathing test. The challenge is to improve the weaning of patients who fail that first test. We have methods that can be referred to as traditional, such as the T-tube, pressure support or synchronized intermittent mandatory ventilation (SIMV). In recent years, however, new applications of usual techniques as noninvasive ventilation, new ventilation methods such as automatic tube compensation (ATC), mandatory minute ventilation (MMV), adaptive support ventilation or automatic weaning systems based on pressure support have been described. Their possible role in weaning from mechanical ventilation among patients with difficult or prolonged weaning remains to be established. Copyright © 2012 Elsevier España, S.L. and SEMICYUC. All rights reserved.
Variability in the Milky Way: Contact Binaries as Diagnostic Tools
NASA Astrophysics Data System (ADS)
de Grijs, R.; Chen, X.; Deng, L.
2017-07-01
We used the 50 cm Binocular Network (50BiN) telescope at Delingha Station (Qinghai Province) of Purple Mountain Observatory (Chinese Academy of Sciences) to obtain simultaneous V- and R-band observations of the old open cluster NGC 188. Our aim was a search for populations of variable stars. We derived light-curve solutions for six W Ursae Majoris (W UMa) eclipsing-binary systems and estimated their orbital parameters. The resulting distance to the W UMas is independent of the physical characteristics of the host cluster. We next determined the current best period-luminosity relations for contact binaries (CBs; scatter σ<0.10 mag). We conclude that CBs can be used as distance tracers with better than 5% uncertainty. We apply our new relations to the 102 CBs in the Large Magellanic Cloud, which yields a distance modulus of (m-M)V,0=18.41±0.20 mag.
Alternatives to currently used antimalarial drugs: in search of a magic bullet.
Bhagavathula, Akshaya Srikanth; Elnour, Asim Ahmed; Shehab, Abdulla
2016-11-04
Malaria is a major cause of morbidity and mortality in many African countries and parts of Asia and South America. Novel approaches to combating the disease have emerged in recent years and several drug candidates are now being tested clinically. However, it is long before these novel drugs can hit the market, especially due to a scarcity of safety and efficacy data.To reduce the malaria burden, the Medicines for Malaria Venture (MMV) was established in 1999 to develop novel medicines through industry and academic partners' collaboration. However, no reviews were focused following various preclinical and clinical studies published since the MMV initiation (2000) to till date.We identify promising approaches in the global portfolio of antimalarial medicines, and highlight challenges and patient specific concerns of these novel molecules. We discuss different clinical studies focusing on the evaluation of novel drugs against malaria in different human trials over the past five years.The drugs KAE609 and DDD107498 are still being evaluated in Phase I trials and preclinical developmental studies. Both the safety and efficacy of novel compounds such as KAF156 and DSM265 need to be assessed further, especially for use in pregnant women. Synthetic non-artemisinin ozonides such as OZ277 raised concerns in terms of its insufficient efficacy against high parasitic loads. Aminoquinoline-based scaffolds such as ferroquine are promising but should be combined with good partner drugs for enhanced efficacy. AQ-13 induced electrocardiac events, which led to prolonged QTc intervals. Tafenoquine, the only new anti-relapse scaffold for patients with a glucose-6-phosphate dehydrogenase deficiency, has raised significant concerns due to its hemolytic activity. Other compounds, including methylene blue (potential transmission blocker) and fosmidomycin (DXP reductoisomerase inhibitor), are available but cannot be used in children.At this stage, we are unable to identify a single magic bullet against malaria. Future studies should focus on effective single-dose molecules that can act against all stages of malaria in order to prevent transmission. Newer medicines have also raised concerns in terms of efficacy and safety. Overall, more evidence is needed to effectively reduce the current malaria burden. Treatment strategies that target the blood stage with transmission-blocking properties are needed to prevent future drug resistance.
NASA Astrophysics Data System (ADS)
Mahoney, C.; März, C.; Wagner, T.
2016-12-01
It is well known that for geochemical studies on ancient rocks, outcrop samples can be compromised by present-day weathering. This raises the fundamental question, if only outcrop samples are available, how reliable can paleoenvironmental reconstructions be? To answer this question, shale samples have been gathered from Cretaceous outcrops of the Eastern Cordillera of Colombia, and analysed by XRF and Fe speciation in order to investigate paleo-redox conditions in this margin basin of the Proto-Atlantic. The samples are consistently depleted (relative to average shale) in redox-related trace metals and in total Fe indicating oxic conditions, whereas Fe speciation (highly reactive over total Fe) indicates anoxic conditions. We ask if this depletion in trace metals and total Fe is due to a lack of primary supply from the depositional environment, or if is it caused by modern oxidative outcrop weathering in this tropical mountainous setting? Our results from artificial weathering experiments confirm that certain trace metals U, Zn and Mo are easily leached from the samples, whereas Fe is quantitatively retained in the samples due to conversion of pyrite and siderite to Fe oxides. Pristine samples from wells in the adjacent Middle Magdalena Valley Basin (MMV) also exhibit total Fe depletion, but are up to 2000-fold enriched in Mo. This combined evidence indicates that the depletion of trace metals may be due to contemporary weathering, but there has to be a paleoenvironmental reason behind the low total Fe signature. The Guiana Shield was the probable source of sediment to the Cretaceous basin. The Chemical Index of Alteration suggest the source of detrital material was initially highly weathered (average 83, maximum 95). Ancient laterites have been identified on the Guiana Shield, and retention of Fe in these laterites may explain the low Fe input into the Eastern Cordillera basin. These results confirm that trace metal-based redox proxies may be seriously affected by oxidative weathering in outcrops, and caution should be applied when using such samples. But it also appears that due to the extreme chemical weathering in the provenance area, the Eastern Cordillera basin (and adjacent MMV basin) was unusually Fe-depleted throughout the Cretaceous, and this geochemical signal is preserved even in weathered outcrop samples.
76 FR 78009 - Information Collection; Implementation of Information Technology Security Provision
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-15
...] Information Collection; Implementation of Information Technology Security Provision AGENCY: General Services... collection requirement regarding Implementation of Information Technology Security Provision. Public comments... Information Collection 3090- 0294, Implementation of Information Technology Security Provision, by any of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-11
... Federal Implementation Plan for Implementing Best Available Retrofit Technology for Four Corners Power... Implementation Plan (FIP) to implement the Best Available Retrofit Technology (BART) requirement of the Regional... given the uncertainties in the electrical market in Arizona, EPA is proposing to extend the date by...
Prompt optical emission from gamma-ray bursts
NASA Astrophysics Data System (ADS)
Kehoe, Robert; Akerlof, Karl; Balsano, Richard; Barthelmy, Scott; Bloch, Jeff; Butterworth, Paul; Casperson, Don; Cline, Tom; Fletcher, Sandra; Frontera, Fillippo; Gisler, Galen; Heise, John; Hills, Jack; Hurley, Kevin; Lee, Brian; Marshall, Stuart; McKay, Tim; Pawl, Andrew; Piro, Luigi; Priedhorsky, Bill; Szymanski, John; Wren, Jim
The Robotic Optical Transient Search Experiment (ROTSE) seeks to measure contemporaneous and early afterglow optical emission from gamma-ray bursts (GRBs). The ROTSE-I telescope array has been fully automated and responding to burst alerts from the GRB Coordinates Network since March 1998, taking prompt optical data for 30 bursts in its first year. We will briefly review observations of GRB990123 which revealed the first detection of an optical burst occurring during the gamma-ray emission, reaching 9th magnitude at its peak. In addition, we present here preliminary optical results for seven other gamma-ray bursts. No other optical counterparts were seen in this analysis, and the best limiting senisitivities are mV > 13.0 at 14.7 seconds after the gamma-ray rise, and mmV > 16.4 at 62 minutes. These are the most stringent limits obtained for GRB optical counterpart brightness in the first hour after the burst. This analysis suggests that there is not a strong correlation between optical flux and gamma-ray emission.
Chatterjee, Arnab K; Yeung, Bryan KS
2012-01-01
Antimalarial drug discovery has historically benefited from the whole-cell (phenotypic) screening approach to identify lead molecules in the search for new drugs. However over the past two decades there has been a shift in the pharmaceutical industry to move away from whole-cell screening to target-based approaches. As part of a Wellcome Trust and Medicines for Malaria Venture (MMV) funded consortium to discover new blood-stage antimalarials, we used both approaches to identify new antimalarial chemotypes, two of which have progressed beyond the lead optimization phase and display excellent in vivo efficacy in mice. These two advanced series were identified through a cell-based optimization devoid of target information and in this review we summarize the advantages of this approach versus a target-based optimization. Although the each lead optimization required slightly different medicinal chemistry strategies, we observed some common issues across the different the scaffolds which could be applied to other cell based lead optimization programs. PMID:22242845
Resistance genes in barley (Hordeum vulgare L.) and their identification with molecular markers.
Chełkowski, Jerzy; Tyrka, Mirosław; Sobkiewicz, Andrzej
2003-01-01
Current information on barley resistance genes available from scientific papers and on-line databases is summarised. The recent literature contains information on 107 major resistance genes (R genes) against fungal pathogens (excluding powdery mildew), pathogenic viruses and aphids identified in Hordeum vulgare accessions. The highest number of resistance genes was identified against Puccinia hordei, Rhynchosporium secalis, and the viruses BaYMV and BaMMV, with 17, 14 and 13 genes respectively. There is still a lot of confusion regarding symbols for R genes against powdery mildew. Among the 23 loci described to date, two regions Mla and Mlo comprise approximately 31 and 25 alleles. Over 50 R genes have already been localised and over 30 mapped on 7 barley chromosomes. Four barley R genes have been cloned recently: Mlo, Rpg1, Mla1 and Mla6, and their structures (sequences) are available. The paper presents a catalogue of barley resistance gene symbols, their chromosomalocation and the list of available DNA markers useful in characterising cultivars and breeding accessions.
77 FR 2734 - Health Information Technology Implementation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-19
... Information Technology Implementation AGENCY: Health Resources and Services Administration, HHS. ACTION... Technology Implementation for Health Center Controlled Networks (HCCN) funds originally awarded to Community... advance information technology resources of the Tennessee's medically underserved communities, TPCA has...
77 FR 55217 - Health Information Technology Implementation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-07
... Information Technology Implementation AGENCY: Health Resources and Services Administration (HRSA), Department... Technology Implementation for Health Center Controlled Networks (HCCN) funds originally awarded to Southwest... effective use of Health Information Technology (HIT). SUPPLEMENTARY INFORMATION: Former Grantee of Record...
ERIC Educational Resources Information Center
Bellamy, Al
2007-01-01
This study explored influences that perceptions of new technology implementation and planning processes, and dimensions of organizational climate have on perceptions of new technology deployment effectiveness. It also examined the extent to which dimensions of organizational climate moderates the relationships among new technology implementation,…
A systems approach to purchasing and implementing new technology.
Kinney, Kristin
2007-01-01
There are many risks associated with purchasing and implementing new technology. The challenge is to reduce these risks to gain maximum benefit from the new technology purchased. In the high-cost world of healthcare, there is little room for wasting time and money related to technology implementation. If the workflow of the current system is not adequately understood before purchasing and implementing a new technology, that technology may mask underlying problems and/or create new ones. The purpose of this article is to present a framework for analyzing the current process or system, identifying the strengths and the areas in need of improvement. A thorough understanding of the problems with the current system and the barriers to change is necessary to ensure the selection of the "right" technology and promote its implementation.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 5 2011-10-01 2011-10-01 false Health information technology implementation... CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.338 Health information technology implementation advance planning document...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 5 2012-10-01 2012-10-01 false Health information technology implementation... CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.338 Health information technology implementation advance planning document...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 5 2014-10-01 2014-10-01 false Health information technology implementation... CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.338 Health information technology implementation advance planning document...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 5 2013-10-01 2013-10-01 false Health information technology implementation... CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.338 Health information technology implementation advance planning document...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 5 2010-10-01 2010-10-01 false Health information technology implementation... CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.338 Health information technology implementation advance planning document...
Steps toward a Technology for the Diffusion of Innovations.
ERIC Educational Resources Information Center
Stolz, Stephanie B.
Research-based technologies for solving problems currently exist but are not being widely implemented. Although user variables, program effectiveness, and political considerations have been documented as correlates of implementation, general non-implementation of the technology still exists, due to a lack of methods. A technology of dissemination…
Challenges in Technology Implementation for Learning Spaces in Higher Education
ERIC Educational Resources Information Center
Lewis, Bryan; Starsia, Gerald
2009-01-01
The design and implementation of technology can prove a particularly daunting challenge for campus planners and project designers. Specialization is required for the selection and implementation of technologies including the familiar network, telecommunications, and data-processing functions, and also the more esoteric emerging technology labs and…
Langhan, Melissa L.; Riera, Antonio; Kurtz, Jordan C.; Schaeffer, Paula; Asnes, Andrea G.
2015-01-01
Objective Technologies are not always successfully implemented into practise. We elicited experiences of acute care providers with the introduction of technology and identified barriers and facilitators in the implementation process. Methods A qualitative study using one-on-one interviews among a purposeful sample of 19 physicians and nurses within ten emergency departments and intensive care units was performed. Grounded theory, iterative data analysis and the constant comparative method were used to inductively generate ideas and build theories. Results Five major categories emerged: decision-making factors, the impact on practise, technology's perceived value, facilitators and barriers to implementation. Barriers included negative experiences, age, infrequent use, and access difficulties. A positive outlook, sufficient training, support staff, and user friendliness were facilitators. Conclusions This study describes strategies implicated in the successful implementation of newly adopted technology in acute care settings. Improved implementation methods and evaluation of implementation processes are necessary for successful adoption of new technology. PMID:25367721
Rangachari, Pavani
2014-12-01
Despite the federal policy momentum towards "meaningful use" of Electronic Health Records, the healthcare organizational literature remains replete with reports of unintended adverse consequences of implementing Electronic Health Records, including: increased work for clinicians, unfavorable workflow changes, and unexpected changes in communication patterns & practices. In addition to being costly and unsafe, these unintended adverse consequences may pose a formidable barrier to "meaningful use" of Electronic Health Records. Correspondingly, it is essential for hospital administrators to understand and detect the causes of unintended adverse consequences, to ensure successful implementation of Electronic Health Records. The longstanding Technology-in-Practice framework emphasizes the role of human agency in enacting structures of technology use or "technologies-in-practice." Given a set of unintended adverse consequences from health information technology implementation, this framework could help trace them back to specific actions (types of technology-in-practice) and institutional conditions (social structures). On the other hand, the more recent Knowledge-in-Practice framework helps understand how information and communication technologies ( e.g. , social knowledge networking systems) could be implemented alongside existing technology systems, to create new social structures, generate new knowledge-in-practice, and transform technology-in-practice. Therefore, integrating the two literature streams could serve the dual purpose of understanding and overcoming unintended adverse consequences of Electronic Health Record implementation. This paper seeks to: (1) review the theoretical literatures on technology use & implementation, and identify a framework for understanding & overcoming unintended adverse consequences of implementing Electronic Health Records; (2) outline a broad project proposal to test the applicability of the framework in enabling "meaningful use" of Electronic Health Records in a healthcare context; and (3) identify strategies for successful implementation of Electronic Health Records in hospitals & health systems, based on the literature review and application.
Beyond usability: designing effective technology implementation systems to promote patient safety.
Karsh, B-T
2004-10-01
Evidence is emerging that certain technologies such as computerized provider order entry may reduce the likelihood of patient harm. However, many technologies that should reduce medical errors have been abandoned because of problems with their design, their impact on workflow, and general dissatisfaction with them by end users. Patient safety researchers have therefore looked to human factors engineering for guidance on how to design technologies to be usable (easy to use) and useful (improving job performance, efficiency, and/or quality). While this is a necessary step towards improving the likelihood of end user satisfaction, it is still not sufficient. Human factors engineering research has shown that the manner in which technologies are implemented also needs to be designed carefully if benefits are to be realized. This paper reviews the theoretical knowledge on what leads to successful technology implementation and how this can be translated into specifically designed processes for successful technology change. The literature on diffusion of innovations, technology acceptance, organisational justice, participative decision making, and organisational change is reviewed and strategies for promoting successful implementation are provided. Given the rapid and ever increasing pace of technology implementation in health care, it is critical for the science of technology implementation to be understood and incorporated into efforts to improve patient safety.
RFID in the healthcare supply chain: usage and application.
Kumar, Sameer; Swanson, Eric; Tran, Thuy
2009-01-01
The purposes of this study are to first, determine the most efficient and cost effective portions of the healthcare supply chain in which radio frequency identification devices (RFID) can be implemented. Second, provide specific examples of RFID implementation and show how these business applications will add to the effectiveness of the healthcare supply chain. And third, to describe the current state of RFID technology and to give practical information for managers in the healthcare sector to make sound decisions about the possible implementation of RFID technology within their organizations. Healthcare industry literature was reviewed and examples of specific instances of RFID implementation were examined using an integrated simulation model developed with Excel, @Risk and Visio software tools. Analysis showed that the cost of implementing current RFID technology is too expensive for broad and sweeping implementation within the healthcare sector at this time. However, several example applications have been identified in which this technology can be effectively leveraged in a cost-effective way. This study shows that RFID technology has come a long way in the recent past and has potential to improve healthcare sector productivity and efficiency. Implementation by large companies such as Wal-mart has helped to make the technology become much more economical in its per unit cost as well as its supporting equipment and training costs. The originality of this study lies in the idea that few practical and pragmatic approaches have been taken within the academic field of study for the implementation of RFID into the healthcare supply chain. Much of the research has focused on specific companies or portions of the supply chain and not the entire supply chain. Also, many of the papers have discussed the future of the supply chain that is heavily dependent on advances in RFID technology. A few viable applications of how RFID technology can be implemented in the healthcare supply chain are presented and how the current state of technology limits the broad use and implementation of this technology in the healthcare industry.
COREBA (cognition-oriented emergent behavior architecture)
NASA Astrophysics Data System (ADS)
Kwak, S. David
2000-06-01
Currently, many behavior implementation technologies are available for modeling human behaviors in Department of Defense (DOD) computerized systems. However, it is commonly known that any single currently adopted behavior implementation technology is not so capable of fully representing complex and dynamic human decision-making and cognition behaviors. The author views that the current situation can be greatly improved if multiple technologies are integrated within a well designed overarching architecture that amplifies the merits of each of the participating technologies while suppressing the limitations that are inherent with each of the technologies. COREBA uses an overarching behavior integration architecture that makes the multiple implementation technologies cooperate in a homogeneous environment while collectively transcending the limitations associated with the individual implementation technologies. Specifically, COREBA synergistically integrates Artificial Intelligence and Complex Adaptive System under Rational Behavior Model multi-level multi- paradigm behavior architecture. This paper will describe applicability of COREBA in DOD domain, behavioral capabilities and characteristics of COREBA and how the COREBA architectural integrates various behavior implementation technologies.
Ethical considerations regarding the implementation of new technologies and techniques in surgery.
Strong, Vivian E; Forde, Kenneth A; MacFadyen, Bruce V; Mellinger, John D; Crookes, Peter F; Sillin, Lelan F; Shadduck, Phillip P
2014-08-01
Ethical considerations relevant to the implementation of new surgical technologies and techniques are explored and discussed in practical terms in this statement, including (1) How is the safety of a new technology or technique ensured?; (2) What are the timing and process by which a new technology or technique is implemented at a hospital?; (3) How are patients informed before undergoing a new technology or technique?; (4) How are surgeons trained and credentialed in a new technology or technique?; (5) How are the outcomes of a new technology or technique tracked and evaluated?; and (6) How are the responsibilities to individual patients and society at large balanced? The following discussion is presented with the intent to encourage thought and dialogue about ethical considerations relevant to the implementation of new technologies and new techniques in surgery.
Beyond technology acceptance to effective technology use: a parsimonious and actionable model.
Holahan, Patricia J; Lesselroth, Blake J; Adams, Kathleen; Wang, Kai; Church, Victoria
2015-05-01
To develop and test a parsimonious and actionable model of effective technology use (ETU). Cross-sectional survey of primary care providers (n = 53) in a large integrated health care organization that recently implemented new medication reconciliation technology. Surveys assessed 5 technology-related perceptions (compatibility with work values, implementation climate, compatibility with work processes, perceived usefulness, and ease of use) and 1 outcome variable, ETU. ETU was measured as both consistency and quality of technology use. Compatibility with work values and implementation climate were found to have differential effects on consistency and quality of use. When implementation climate was strong, consistency of technology use was high. However, quality of technology use was high only when implementation climate was strong and values compatibility was high. This is an important finding and highlights the importance of users' workplace values as a key determinant of quality of use. To extend our effectiveness in implementing new health care information technology, we need parsimonious models that include actionable determinants of ETU and account for the differential effects of these determinants on the multiple dimensions of ETU. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Open modular architecture controls at GM Powertrain: technology and implementation
NASA Astrophysics Data System (ADS)
Bailo, Clark P.; Yen, C. J.
1997-01-01
General Motors Powertrain Group (GMPTG) has been the leader in implementing open, modular architecture controller (OMAC) technologies in its manufacturing applications since 1986. The interest in OMAC has been greatly expanded for the past two years because of the advancement of personal computer technologies and the publishing of the OMAC whitepaper by the US automotive companies stating the requirements of OMAC technologies in automotive applications. The purpose of this paper is to describe the current OMAC projects and the future direction of implementation at GMPTG. An overview of the OMAC project and the definition of the OMAC concept are described first. The rationale of pursuing open technologies is explained from the perspective of GMPTG in lieu of its agile manufacturing strategy. Examples of existing PC-based control applications are listed to demonstrate the extensive commitment to PC-based technologies that has already been put in place. A migration plan form PC-based to OMAC-based systems with the thorough approach of validation are presented next to convey the direction that GMPTG is taking in implementing OMAC technologies. Leveraged technology development projects are described to illustrate the philosophy and approaches toward the development of OMAC technologies at GMPTG. Finally, certain implementation issues are discussed to emphasize efforts that are still required to have successful implementations of OMAC systems.
Code of Federal Regulations, 2011 CFR
2011-10-01
... HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.205 Content.... The Healthcare Information Technology Standards Panel (HITSP) Summary Documents Using HL7 CCD...
Code of Federal Regulations, 2010 CFR
2010-10-01
... HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.205 Content.... The Healthcare Information Technology Standards Panel (HITSP) Summary Documents Using HL7 CCD...
Technology Implementation in Education--Identifying Barriers to Fidelity
ERIC Educational Resources Information Center
Dennis, William J.; Johnson, Daniel L.; Monroe, Arla K.
2012-01-01
This report describes a problem-based learning project focused on determining the barriers to the implementation of technological innovations. Research findings offered evidence that properly executed technology implementation is an instructional variable related to student achievement; yet, school district leaders are faced with the problem of…
Technology Implementation in Education--Identifying Barriers to Fidelity
ERIC Educational Resources Information Center
Monroe, Arla K.; Dennis, William J.; Johnson, Daniel L.
2012-01-01
This report describes a problem-based learning project focused on determining the barriers to the implementation of technological innovations. that properly executed technology implementation is an instructional variable related to student achievement; yet, school district leaders are faced with the problem of recognizing and identifying the…
Code of Federal Regulations, 2010 CFR
2010-10-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.202 [Reserved] ...
Code of Federal Regulations, 2011 CFR
2011-10-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.202 [Reserved] ...
Student Support that Works: A Solid Approach.
ERIC Educational Resources Information Center
Lang, Kathy J.; Bielejeski, Ruth
The College of Saint Benedict and Saint John's University (Minnesota), two coordinate, liberal arts colleges, have implemented a cost-effective student information technology (IT) support system. Project IMPACT (Implementing Academic Technology), a 5-year, $10 million plan to upgrade the technology for student and faculty use, was implemented in…
2012-01-01
Background Rehabilitation technology for upper limb training of stroke patients may play an important role as therapy tool in future, in order to meet the increasing therapy demand. Currently, implementation of this technology in the clinic remains low. This study aimed at identifying criteria and conditions that people, involved in development of such technology, should take into account to achieve a (more) successful implementation of the technology in the clinic. Methods A literature search was performed in PubMed and IEEE databases, and semi-structured interviews with therapists in stroke rehabilitation were held, to identify criteria and conditions technology should meet to facilitate (implementation of) technology-assisted arm-hand skills training in rehabilitation therapy of stroke patients. In addition, an implementation strategy frequently applied in general health care was used to compose a stepwise guidance to facilitate successful implementation of this technology in therapy of stroke patients. Implementation-related criteria mentioned by therapists during the interviews were integrated in this guidance. Results Results indicate that, related to therapy content, technology should facilitate repetition of task-related movements, tailored to the patient and patient’s goals, in a meaningful context. Variability and increasing levels of difficulty in exercises should be on offer. Regarding hardware and software design of technology, the system should facilitate quick familiarisation and be easily adjustable to individual patients during therapy by therapists (and assistants). The system should facilitate adaptation to individual patients’ needs and their progression over time, should be adjustable as to various task-related variables, should be able to provide instructions and feedback, and should be able to document patient’s progression. The implementation process of technology in the clinic is provided as a stepwise guidance that consists of five phases therapists have to go through. The guidance includes criteria and conditions that motivate therapists, and make it possible for them, to actually use technology in their daily clinical practice. Conclusions The reported requirements are important as guidance for people involved in the development of rehabilitation technology for arm-hand therapy of stroke patients. The stepwise guide provides a tool for facilitating successful implementation of technology in clinical practice, thus meeting future therapy demand. PMID:22856548
45 CFR 170.207 - Vocabulary standards for representing electronic health information.
Code of Federal Regulations, 2011 CFR
2011-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.207 Vocabulary standards for representing electronic...
45 CFR 170.207 - Vocabulary standards for representing electronic health information.
Code of Federal Regulations, 2013 CFR
2013-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.207 Vocabulary standards for representing electronic...
45 CFR 170.207 - Vocabulary standards for representing electronic health information.
Code of Federal Regulations, 2014 CFR
2014-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.207 Vocabulary standards for representing electronic...
45 CFR 170.207 - Vocabulary standards for representing electronic health information.
Code of Federal Regulations, 2012 CFR
2012-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information Technology § 170.207 Vocabulary standards for representing electronic...
Implementation of Paste Backfill Mining Technology in Chinese Coal Mines
Chang, Qingliang; Zhou, Huaqiang; Bai, Jianbiao
2014-01-01
Implementation of clean mining technology at coal mines is crucial to protect the environment and maintain balance among energy resources, consumption, and ecology. After reviewing present coal clean mining technology, we introduce the technology principles and technological process of paste backfill mining in coal mines and discuss the components and features of backfill materials, the constitution of the backfill system, and the backfill process. Specific implementation of this technology and its application are analyzed for paste backfill mining in Daizhuang Coal Mine; a practical implementation shows that paste backfill mining can improve the safety and excavation rate of coal mining, which can effectively resolve surface subsidence problems caused by underground mining activities, by utilizing solid waste such as coal gangues as a resource. Therefore, paste backfill mining is an effective clean coal mining technology, which has widespread application. PMID:25258737
Implementation of paste backfill mining technology in Chinese coal mines.
Chang, Qingliang; Chen, Jianhang; Zhou, Huaqiang; Bai, Jianbiao
2014-01-01
Implementation of clean mining technology at coal mines is crucial to protect the environment and maintain balance among energy resources, consumption, and ecology. After reviewing present coal clean mining technology, we introduce the technology principles and technological process of paste backfill mining in coal mines and discuss the components and features of backfill materials, the constitution of the backfill system, and the backfill process. Specific implementation of this technology and its application are analyzed for paste backfill mining in Daizhuang Coal Mine; a practical implementation shows that paste backfill mining can improve the safety and excavation rate of coal mining, which can effectively resolve surface subsidence problems caused by underground mining activities, by utilizing solid waste such as coal gangues as a resource. Therefore, paste backfill mining is an effective clean coal mining technology, which has widespread application.
NASA Astrophysics Data System (ADS)
Boriack, Anna Christine
The purpose of this study is to examine teachers' perceptions of professional development and changes in classroom practice. A proposed conceptual framework for effective professional development that results in changes in classroom practices was developed. Data from two programs that provided professional development to teachers in the areas of technology, mathematics, and science was used to inform the conceptual framework. These two programs were Target Technology in Texas (T3) and Mathematics, Science, and Technology Teacher Preparation Academies (MSTTPA). This dissertation used a multiple article format to explore each program separately, yet the proposed conceptual framework allowed for comparisons to be made between the two programs. The first study investigated teachers' perceptions of technology-related professional development after their districts had received a T3 grant. An online survey was administrated to all teachers to determine their perceptions of technology-related professional development along with technology self-efficacy. Classroom observations were conducted to determine if teachers were implementing technology. The results indicated that teachers did not perceive professional development as being effective and were not implementing technology in their classrooms. Teachers did have high technology self-efficacy and perceived adequate school support, which implies that effective professional development may be a large factor in whether or not teachers implement technology in their classrooms. The second study evaluated participants' perceptions of the effectiveness of mathematics and science professional development offered through a MSTTP academy. Current and former participants completed an online survey which measured their perceptions of academy activities and school environment. Participants also self-reported classroom implementation of technology. Interviews and open-ended survey questions were used to provide further insight into academy activities. The results indicated that academy participants perceived effective academy activities along with a supportive school environment. Additionally, participants reported sometimes implementing technology in their classrooms. These findings suggest that several factors might influence the successful classroom implementation of professional development. The data which supports the conceptual framework shows that effective professional development may play a key role in successful classroom implementation. Future professional development activities should be designed around characteristics for effective professional development to increase the likelihood that classroom implementation might occur.
Mobile Learning and Integration of Mobile Technologies in Education
ERIC Educational Resources Information Center
Keengwe, Jared; Bhargava, Malini
2014-01-01
Mobile technologies have a huge potential to transform education provided these technologies are designed and implemented in such a way that they are relevant to the social and cultural context of learning. Clearly, the application, implementation, and design of mobile technology in the global educational context pose technological and…
Designing and Implementing an Assistive Technology Lab for Postsecondary Education
ERIC Educational Resources Information Center
Jones, Beth; Williams, Nichole; Rudinger, Belinda
2018-01-01
A literature review discusses how teacher knowledge of assistive technology significantly impacts student success with assistive technology and that many teachers enter the field feeling unprepared to implement these technologies with students. This article explores one university's process in setting up an assistive technology laboratory for…
Alternative Fuels Data Center: Ten Ways You Can Implement Alternative Fuels
and Energy-Efficient Vehicle Technologies Ten Ways You Can Implement Alternative Fuels and Energy-Efficient Vehicle Technologies to someone by E-mail Share Alternative Fuels Data Center: Ten Ways You Can Implement Alternative Fuels and Energy-Efficient Vehicle Technologies on Facebook Tweet about
The Technology Coach: Implementing Instructional Technology in Kean University's ESL Program
ERIC Educational Resources Information Center
Snyder, Sharon C.; Best, Linda; Griffith, Ruth P.; Nelson, Charles
2011-01-01
Faculty involved in implementing a grant to incorporate technology into post-secondary ESL teaching and learning describe the coaching model they used to do this. The authors explain how they drew from principles of literacy coaching to develop and implement their model; describe their experiences in working with coachees; discuss technology…
Examining Health Information Technology Implementation Success Factors in Critical Access Hospitals
ERIC Educational Resources Information Center
Monkman, Blake D.
2016-01-01
As the role of information technology increases throughout the world, healthcare providers in the United States face industry and governmental pressures to implement health information technology (HIT) as a tool to improve healthcare costs, quality, and safety. The problem addressed in this study was the relatively low HIT implementation success…
ERIC Educational Resources Information Center
Saleem, Mohammed M.
2009-01-01
This exploratory study of the implementation of computer technology in an American Islamic private school leveraged the case study methodology and ethnographic methods informed by symbolic interactionism and the framework of the Muslim Diaspora. The study focused on describing the implementation of computer technology and identifying the…
ERIC Educational Resources Information Center
Sarfo, Frederick Kwaku; Amankwah, Francis; Baafi-Frimpong, Stephen; Asomani, Joseph
2017-01-01
Research findings in the literature show that teachers' concern about change process is extremely personal and it influences the implementation of innovation. This study aimed at assessing information and communication technology teachers' stages of concern regarding the implementation of information and communication technology (ICT) curriculum…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-06
... Acquisition Regulation; Implementation of Information Technology Security Provision AGENCY: Office of... orders that include information technology (IT) supplies, services and systems. DATES: Effective Date... 6, 2012 that include information technology (IT) supplies, services and systems with security...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-15
... Acquisition Regulation; Implementation of Information Technology Security Provision AGENCY: Office of... information technology (IT) supplies, services and systems with security requirements. DATES: Effective Date... effective date that include information technology (IT) supplies, services and systems with security...
Tietze, Mari F; Williams, Josie; Galimbertti, Marisa
2009-01-01
This grant involved a hospital collaborative for excellence using information technology over 3-year period. The project activities focused on the improvement of patient care safety and quality in Southern rural and small community hospitals through the use of technology and education. The technology component of the design involved the implementation of a Web-based business analytic tool that allows hospitals to view data, create reports, and analyze their safety and quality data. Through a preimplementation and postimplementation comparative design, the focus of the implementation team was twofold: to recruit participant hospitals and to implement the technology at each of the 66 hospital sites. Rural hospitals were defined as acute care hospitals located in a county with a population of less than 100 000 or a state-administered Critical Access Hospital, making the total study population target 188 hospitals. Lessons learned during the information technology implementation of these hospitals are reflective of the unique culture, financial characteristics, organizational structure, and technology architecture of rural hospitals. Specific steps such as recruitment, information technology assessment, conference calls for project planning, data file extraction and transfer, technology training, use of e-mail, use of telephones, personnel management, and engaging information technology vendors were found to vary greatly among hospitals.
Vest, Joshua R
2010-12-01
The provisions of the American Recovery & Reinvestment Act increased the likelihood of more widespread health information exchange (HIE), the electronic transfer of patient-level information between organizations, by essentially mandating the use of electronic health record systems. While important, the sparse body of research on HIE efforts and anecdotal reports indicate the barriers to HIE adoption and implementation include factors beyond simply the presence or absence of a specific technology. This paper examines those technological, organizational, and environmental factors that are associated with both HIE adoption and implementation in a sample of 4830 U.S. hospitals. Factors associated with adoption and implementation were modeled using random-intercept logistic regression. Consistent with a perspective that adoption and implementation are different phenomena, many factors associated with an increased odds of adoption, were unassociated with implementation and vice versa. Non-profit status, public hospitals, more live and operation applications, more emergency room visits, network membership, and the presence of physician portals all increased hospitals' odds of HIE adoption. However, only network membership increased the odds of HIE implementation, whereas competition decreased those odds significantly. This study agreed with earlier case-studies and anecdotal reports that factors beyond technology were important to both adoption and implementation. While current U.S. policy on healthcare information technology adoption focuses on technological barriers, many other non-technological factors may ultimately hinder effective HIE. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Agustin, R. R.; Liliasari; Sinaga, P.; Rochintaniawati, D.
2018-05-01
The use of technology into science learning encounters problems. One of the problem is teachers’ less technological pedagogical and content knowledge (TPACK) on the implementation of technology itself. The purpose of this study was to investigate science teachers’ experience in using digital technology into science classroom. Through this study science teachers’ technological knowledge (TK) and technological content knowledge (TCK) can be unpacked. Descriptive method was used to depict science teachers’ TK and TCK through questionnaire that consisted of 20 questions. Subjects of this study were 25 science teachers in Bandung, Indonesia. The study was conducted in the context of teacher professional training. Result shows that science teachers still have less TK, yet they have high TCK. The teachers consider characteristics of concepts as main aspect for implementing technology into science teaching. This finding describes teachers’ high technological content knowledge. Meanwhile, science teachers’ technological knowledge was found to be still low since only few of them who can exemplify digital technology that can be implemented into several science concept. Therefore, training about technology implementation into science teaching and learning is necessary as a means to improve teachers’ technological knowledge.
Factors related to the implementation and diffusion of new technologies: a pilot study
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-06-01
In order to develop an understanding of how government intervention affects the processes of implementation and diffusion of new technologies, case studies of 14 technologies were carried out: automobiles; broadcast radio; frozen foods; black and white TV; color TV; polio vaccine; supersonic transport; fluoridation of water supplies; computer-aided instruction; basic oxygen process for steel; numerical control in manufacturing; digital computers; lasers; and integrated circuit. The key factors, their motivations for implementing/adopting the technology (or not doing so), the interactions among the key factors, and how these affected implementation/adoption are examined.
45 CFR 170.200 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.200 - Applicability.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.200 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.200 - Applicability.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.200 - Applicability.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
Jeskey, Mary; Card, Elizabeth; Nelson, Donna; Mercaldo, Nathaniel D; Sanders, Neal; Higgins, Michael S; Shi, Yaping; Michaels, Damon; Miller, Anne
2011-10-01
To report an exploratory action-research process used during the implementation of continuous patient monitoring in acute post-surgical nursing units. Substantial US Federal funding has been committed to implementing new health care technology, but failure to manage implementation processes may limit successful adoption and the realisation of proposed benefits. Effective approaches for managing barriers to new technology implementation are needed. Continuous patient monitoring was implemented in three of 13 medical/surgical units. An exploratory action-feedback approach, using time-series nurse surveys, was used to identify barriers and develop and evaluate responses. Post-hoc interviews and document analysis were used to describe the change implementation process. Significant differences were identified in night- and dayshift nurses' perceptions of technology benefits. Research nurses' facilitated the change process by evolving 'clinical nurse implementation specialist' expertise. Health information technology (HIT)-related patient outcomes are mediated through nurses' acting on new information but HIT designed for critical care may not transfer to acute care settings. Exploratory action-feedback approaches can assist nurse managers in assessing and mitigating the real-world effects of HIT implementations. It is strongly recommended that nurse managers identify stakeholders and develop comprehensive plans for monitoring the effects of HIT in their units. © 2011 Blackwell Publishing Ltd.
ERIC Educational Resources Information Center
Johnston, Katrina M.
2013-01-01
School information systems (SIS) have the potential to cause a change in a school's technical, structural, psycho-social, and managerial systems. Implementation of a technological innovation such as an SIS is not a one-step occurrence; it is a process that occurs over time. Implementing any technological innovation involves active learning…
ERIC Educational Resources Information Center
Kates, Earl B.
2016-01-01
Despite significant investments made by organizations to implement ERP systems and prior research that explored contributing factors of ERP failure, the ERP implementation success rate continues to remain low in practice. Increased technology usage in the workplace coupled with higher dependency on technology to complete project tasks often leads…
Successful Implementation of New Technology Using an Interdepartmental Collaborative Approach.
Tetef, Sue
2017-06-01
The implementation of new technology is vital to the success of health care organizations. New technology provides health care organizations an opportunity to obtain new patients, increase revenue, and stay competitive. In 2014, a union hospital in Southern California successfully implemented a bronchial thermoplasty program. To implement this new technology, the administration created a strategy, identified financial risks and benefits, created an implementation model, established a plan based on Lewin's change model and Roger's diffusion of innovations theory, and recognized adult learning needs through an interdepartmental, open communication, and collaborative approach. In addition, the implementation of the bronchial thermoplasty program allowed the organization to meet the goals, mission, and vision of the organization, which is key to remaining viable and marketable. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.
Selected Technology Lab Activities Implementation Guide.
ERIC Educational Resources Information Center
Portland Public Schools, OR.
These materials supplement state guides for junior high or middle school technology education programs. The materials show instructors how to implement 81 hours of new technology-related activities into existing programs. Introductory materials include a rationale, philosophy, and goals for technology education. Areas of instruction are as…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bernard, E.A.
1995-12-31
The Department of Energy (DOE), in response to the 1992 Federal Facility Compliance Act, has prepared Site Treatment Plans (STP) for the approximately 2,000 waste streams identified within its mixed waste inventory Concurrently, emerging mixed waste treatment technologies are in final development. This paper defines a three-phase process to identify and assess implementation opportunities for these emerging technologies within the STP. It highlights the first phase, functional matching of expected treatment capabilities with proposed treatment requirements. Matches are based on treatment type, regulated contaminant and waste matrix type, for both capabilities and requirements. Results identify specific waste streams and volumesmore » that could be treated by each emerging technology. A study for Plasma Hearth Process, Delphi DETOX{sup sm}, Supercritical Water Oxidation and Vitrification shows that about 200,000 ml of DOE`s mixed waste inventory can potentially be treated by one or more of these emerging technologies. Actual implementations are small fractions of the treatable inventory. Differences between potential and actual implementations must be minimized to accrue optimum benefit from implementation of emerging or alternative treatment technologies. Functional matching is the first phase in identifying and quantifying benefits, addressing technology system and treatment issues, and providing, in part, the basis for STP implementation decisions. DOE, through EM`s Office of Technology Development, has funded this work.« less
45 CFR 170.204 - Functional standards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.202 - Transport standards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.204 - Functional standards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.202 - Transport standards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Public Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.202 - Transport standards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
45 CFR 170.204 - Functional standards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Public Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Standards and Implementation Specifications for Health Information...
Peek, Sebastiaan Theodorus Michaël; Wouters, Eveline J M; Luijkx, Katrien G; Vrijhoef, Hubertus J M
2016-05-03
There is a growing interest in empowering older adults to age in place by deploying various types of technology (ie, eHealth, ambient assisted living technology, smart home technology, and gerontechnology). However, initiatives aimed at implementing these technologies are complicated by the fact that multiple stakeholder groups are involved. Goals and motives of stakeholders may not always be transparent or aligned, yet research on convergent and divergent positions of stakeholders is scarce. To provide insight into the positions of stakeholder groups involved in the implementation of technology for aging in place by answering the following questions: What kind of technology do stakeholders see as relevant? What do stakeholders aim to achieve by implementing technology? What is needed to achieve successful implementations? Mono-disciplinary focus groups were conducted with participants (n=29) representing five groups of stakeholders: older adults (6/29, 21%), care professionals (7/29, 24%), managers within home care or social work organizations (5/29, 17%), technology designers and suppliers (6/29, 21%), and policy makers (5/29, 17%). Transcripts were analyzed using thematic analysis. Stakeholders considered 26 different types of technologies to be relevant for enabling independent living. Only 6 out of 26 (23%) types of technology were mentioned by all stakeholder groups. Care professionals mentioned fewer different types of technology than other groups. All stakeholder groups felt that the implementation of technology for aging in place can be considered a success when (1) older adults' needs and wishes are prioritized during development and deployment of the technology, (2) the technology is accepted by older adults, (3) the technology provides benefits to older adults, and (4) favorable prerequisites for the use of technology by older adults exist. While stakeholders seemed to have identical aims, several underlying differences emerged, for example, with regard to who should pay for the technology. Additionally, each stakeholder group mentioned specific steps that need to be taken to achieve successful implementation. Collectively, stakeholders felt that they need to take the leap (ie, change attitudes, change policies, and collaborate with other organizations); bridge the gap (ie, match technology with individuals and stimulate interdisciplinary education); facilitate technology for the masses (ie, work on products and research that support large-scale rollouts and train target groups on how to use technology); and take time to reflect (ie, evaluate use and outcomes). Stakeholders largely agree on the direction in which they should be heading; however, they have different perspectives with regard to the technologies that can be employed and the work that is needed to implement them. Central to these issues seems to be the tailoring of technology or technologies to the specific needs of each community-dwelling older adult and the work that is needed by stakeholders to support this type of service delivery on a large scale.
Wouters, Eveline JM; Luijkx, Katrien G; Vrijhoef, Hubertus JM
2016-01-01
Background There is a growing interest in empowering older adults to age in place by deploying various types of technology (ie, eHealth, ambient assisted living technology, smart home technology, and gerontechnology). However, initiatives aimed at implementing these technologies are complicated by the fact that multiple stakeholder groups are involved. Goals and motives of stakeholders may not always be transparent or aligned, yet research on convergent and divergent positions of stakeholders is scarce. Objective To provide insight into the positions of stakeholder groups involved in the implementation of technology for aging in place by answering the following questions: What kind of technology do stakeholders see as relevant? What do stakeholders aim to achieve by implementing technology? What is needed to achieve successful implementations? Methods Mono-disciplinary focus groups were conducted with participants (n=29) representing five groups of stakeholders: older adults (6/29, 21%), care professionals (7/29, 24%), managers within home care or social work organizations (5/29, 17%), technology designers and suppliers (6/29, 21%), and policy makers (5/29, 17%). Transcripts were analyzed using thematic analysis. Results Stakeholders considered 26 different types of technologies to be relevant for enabling independent living. Only 6 out of 26 (23%) types of technology were mentioned by all stakeholder groups. Care professionals mentioned fewer different types of technology than other groups. All stakeholder groups felt that the implementation of technology for aging in place can be considered a success when (1) older adults’ needs and wishes are prioritized during development and deployment of the technology, (2) the technology is accepted by older adults, (3) the technology provides benefits to older adults, and (4) favorable prerequisites for the use of technology by older adults exist. While stakeholders seemed to have identical aims, several underlying differences emerged, for example, with regard to who should pay for the technology. Additionally, each stakeholder group mentioned specific steps that need to be taken to achieve successful implementation. Collectively, stakeholders felt that they need to take the leap (ie, change attitudes, change policies, and collaborate with other organizations); bridge the gap (ie, match technology with individuals and stimulate interdisciplinary education); facilitate technology for the masses (ie, work on products and research that support large-scale rollouts and train target groups on how to use technology); and take time to reflect (ie, evaluate use and outcomes). Conclusions Stakeholders largely agree on the direction in which they should be heading; however, they have different perspectives with regard to the technologies that can be employed and the work that is needed to implement them. Central to these issues seems to be the tailoring of technology or technologies to the specific needs of each community-dwelling older adult and the work that is needed by stakeholders to support this type of service delivery on a large scale. PMID:27143097
Technology Supported Learning and Teaching: A Staff Perspective
ERIC Educational Resources Information Center
O'Donoghue, John, Ed.
2006-01-01
"Technology Supported Learning and Teaching: A Staff Perspective" presents accounts and case studies of first-hand experience in developing, implementing, or evaluating learning technologies. This book highlights the many areas in which practitioners are attempting to implement learning technologies and reflects themes of current topical interest.…
A Resource Guide Identifying Technology Tools for Schools. Appendix
ERIC Educational Resources Information Center
Fox, Christine; Jones, Rachel
2009-01-01
SETDA and NASTID's "Technology Tools for Schools Resource Guide" provides definitions of key technology components and relevant examples, where appropriate as a glossary for educators. The guide also presents essential implementation and infrastructure considerations that decision makers should think about when implementing technology in schools.…
Technology in Community Colleges. ERIC Digest.
ERIC Educational Resources Information Center
McKinney, Kristin
Despite the costs of implementing technology at community colleges, the benefits gained include increased instructor creativity, increased student interest and learning, and greater flexibility of instructional delivery. Instructional technology may be implemented in two ways: first, the use of technology as a simple add-on to enhance current…
ERIC Educational Resources Information Center
Herron, Julie
2010-01-01
This study examined pre-service teachers' responses to implementing technology into elementary mathematics lessons. Instructional Architect (IA) was the web-base technology used by the pre-service teachers. Four themes emerged from the data: (a) insights into technology, (b) struggles with technology, (c) access to the mathematics and (d) learning…
Strengthening 4-H Program Communication through Technology
ERIC Educational Resources Information Center
Robideau, Kari; Santl, Karyn
2011-01-01
Advances in technology are transforming how youth and parents interact with programs. The Strengthening 4-H Communication through Technology project was implemented in eight county 4-H programs in Northwest Minnesota. This article outlines the intentional process used to effectively implement technology in program planning. The project includes:…
ERIC Educational Resources Information Center
Parker, Caroline E.; Stylinski, Cathlyn D.; Bonney, Christina R.; Schillaci, Rebecca; McAuliffe, Carla
2015-01-01
Technology applications aligned with science, technology, engineering, and math (STEM) workplace practices can engage students in real-world pursuits but also present dramatic challenges for classroom implementation. We examined the impact of teacher professional development focused on incorporating these workplace technologies in the classroom.…
Towards a Framework for Managing Risk Associated with Technology-Induced Error.
Borycki, Elizabeth M; Kushniruk, Andre W
2017-01-01
Health information technologies (HIT) promised to streamline and modernize healthcare processes. However, a growing body of research has indicated that if such technologies are not designed, implemented or maintained properly this may lead to an increased incidence of new types of errors which the authors have referred to as "technology-induced errors". In this paper, framework is presented that can be used to manage HIT risk. The framework considers the reduction of technology-induced errors at different stages by managing risks associated with the implementation of HIT. Frameworks that allow health information technology managers to employ proactive and preventative approaches that can be used to manage the risks associated with technology-induced errors are critical to improving HIT safety and managing risk associated with implementing new technologies.
Achieving Technological Literacy in Minnesota.
ERIC Educational Resources Information Center
Lindstrom, Mike
2002-01-01
Describes how Minnesota implemented the Standards for Technological Literacy: Content for the Study of Technology. Includes the timeline, rationale, potential activities and estimated costs associated with all phases, and steps for implementing the plan: investigate, replicate, integrate, and mandate. (JOW)
Safety benefits of implementing adaptive signal control technology : survey results.
DOT National Transportation Integrated Search
2013-01-01
The safety benefits and costs associated with implementing adaptive signal control technology (ASCT) were evaluated in : this study. A user-friendly online survey was distributed to 62 agencies that had implemented ASCT in the United States. : Twenty...
NASA Astrophysics Data System (ADS)
Nogueira, Juan Manuel; Romero, David; Espadas, Javier; Molina, Arturo
2013-02-01
With the emergence of new enterprise models, such as technology-based enterprises, and the large quantity of information generated through technological advances, the Zachman framework continues to represent a modelling tool of great utility and value to construct an enterprise architecture (EA) that can integrate and align the IT infrastructure and business goals. Nevertheless, implementing an EA requires an important effort within an enterprise. Small technology-based enterprises and start-ups can take advantage of EAs and frameworks but, because these enterprises have limited resources to allocate for this task, an enterprise framework implementation is not feasible in most cases. This article proposes a new methodology based on action-research for the implementation of the business, system and technology models of the Zachman framework to assist and facilitate its implementation. Following the explanation of cycles of the proposed methodology, a case study is presented to illustrate the results of implementing the Zachman framework in a technology-based enterprise: PyME CREATIVA, using action-research approach.
Research of negotiation in network trade system based on multi-agent
NASA Astrophysics Data System (ADS)
Cai, Jun; Wang, Guozheng; Wu, Haiyan
2009-07-01
A construction and implementation technology of network trade based on multi-agent is described in this paper. First, we researched the technology of multi-agent, then we discussed the consumer's behaviors and the negotiation between purchaser and bargainer which emerges in the traditional business mode and analysed the key technology to implement the network trade system. Finally, we implement the system.
Considerations in change management related to technology.
Luo, John S; Hilty, Donald M; Worley, Linda L; Yager, Joel
2006-01-01
The authors describe the complexity of social processes for implementing technological change. Once a new technology is available, information about its availability and benefits must be made available to the community of users, with opportunities to try the innovations and find them worthwhile, despite organizational resistances. The authors reviewed the literature from psychiatry, psychology, sociology, business, and technology to distill common denominators for success and failure related to implementing technology. Beneficial technological innovations that are simple to use and obviously save everyone time and effort are easy to inaugurate. However, innovations that primarily serve management rather than subordinates or front-line utilizers may fail, despite considerable institutional effort. This article reviews and outlines several of the more prominent theoretical models governing successful institutional change. Successful implementation of difficult technological changes requires visionary leadership that has carefully considered the benefits, consulted with influence leaders at all organizational levels to spot unintended consequences and sources of resistance, and developed a detailed plan and continuous quality assurance process to foster implementation over time.
Harvey, Gill; Llewellyn, Sue; Maniatopoulos, Greg; Boyd, Alan; Procter, Rob
2018-05-10
Accelerating the implementation of new technology in healthcare is typically complex and multi-faceted. One strategy is to charge a national agency with the responsibility for facilitating implementation. This study examines the role of such an agency in the English National Health Service. In particular, it compares two different facilitation strategies employed by the agency to support the implementation of insulin pump therapy. The research involved an empirical case study of four healthcare organisations receiving different levels of facilitation from the national agency: two received active hands-on facilitation; one was the intended recipient of a more passive, web-based facilitation strategy; the other implemented the technology without any external facilitation. The primary method of data collection was semi-structured qualitative interviews with key individuals involved in implementation. The integrated-PARIHS framework was applied as a conceptual lens to analyse the data. The two sites that received active facilitation from an Implementation Manager in the national agency made positive progress in implementing the technology. In both sites there was a high level of initial receptiveness to implementation. This was similar to a site that had successfully introduced insulin pump therapy without facilitation support from the national agency. By contrast, a site that did not have direct contact with the national agency made little progress with implementation, despite the availability of a web-based implementation resource. Clinicians expressed differences of opinion around the value and effectiveness of the technology and contextual barriers related to funding for implementation persisted. The national agency's intended roll out strategy using passive web-based facilitation appeared to have little impact. When favourable conditions exist, in terms of agreement around the value of the technology, clinician receptiveness and motivation to change, active facilitation via an external agency can help to structure the implementation process and address contextual barriers. Passive facilitation using web-based implementation resources appears less effective. Moving from initial implementation to wider scale-up presents challenges and is an issue that warrants further attention.
Meeks, Derek W; Takian, Amirhossein; Sittig, Dean F; Singh, Hardeep; Barber, Nick
2014-01-01
Objective The intersection of electronic health records (EHR) and patient safety is complex. To examine the applicability of two previously developed conceptual models comprehensively to understand safety implications of EHR implementation in the English National Health Service (NHS). Methods We conducted a secondary analysis of interview data from a 30-month longitudinal, prospective, case study-based evaluation of EHR implementation in 12 NHS hospitals. We used a framework analysis approach to apply conceptual models developed by Sittig and Singh to understand better EHR implementation and use: an eight-dimension sociotechnical model and a three-phase patient safety model (safe technology, safe use of technology, and use of technology to improve safety). Results The intersection of patient safety and EHR implementation and use was characterized by risks involving technology (hardware and software, clinical content, and human–computer interfaces), the interaction of technology with non-technological factors, and improper or unsafe use of technology. Our data support that patient safety improvement activities as well as patient safety hazards change as an organization evolves from concerns about safe EHR functionality, ensuring safe and appropriate EHR use, to using the EHR itself to provide ongoing surveillance and monitoring of patient safety. Discussion We demonstrate the face validity of two models for understanding the sociotechnical aspects of safe EHR implementation and the complex interactions of technology within a healthcare system evolving from paper to integrated EHR. Conclusions Using sociotechnical models, including those presented in this paper, may be beneficial to help stakeholders understand, synthesize, and anticipate risks at the intersection of patient safety and health information technology. PMID:24052536
Meeks, Derek W; Takian, Amirhossein; Sittig, Dean F; Singh, Hardeep; Barber, Nick
2014-02-01
The intersection of electronic health records (EHR) and patient safety is complex. To examine the applicability of two previously developed conceptual models comprehensively to understand safety implications of EHR implementation in the English National Health Service (NHS). We conducted a secondary analysis of interview data from a 30-month longitudinal, prospective, case study-based evaluation of EHR implementation in 12 NHS hospitals. We used a framework analysis approach to apply conceptual models developed by Sittig and Singh to understand better EHR implementation and use: an eight-dimension sociotechnical model and a three-phase patient safety model (safe technology, safe use of technology, and use of technology to improve safety). The intersection of patient safety and EHR implementation and use was characterized by risks involving technology (hardware and software, clinical content, and human-computer interfaces), the interaction of technology with non-technological factors, and improper or unsafe use of technology. Our data support that patient safety improvement activities as well as patient safety hazards change as an organization evolves from concerns about safe EHR functionality, ensuring safe and appropriate EHR use, to using the EHR itself to provide ongoing surveillance and monitoring of patient safety. We demonstrate the face validity of two models for understanding the sociotechnical aspects of safe EHR implementation and the complex interactions of technology within a healthcare system evolving from paper to integrated EHR. Using sociotechnical models, including those presented in this paper, may be beneficial to help stakeholders understand, synthesize, and anticipate risks at the intersection of patient safety and health information technology.
Barzekar, Hosein; Karami, Mahtab
2014-10-01
to examine the organizational factors affecting the application of information technology in hospitals. Since the organizational factors are one of the most important determinants of successful projects, by understanding their impact and identifying them it can help planning a systematic IT implementation. In this cross-sectional descriptive study 110 middle managers were chosen from teaching hospitals. Structured questionnaire was used for the data collection. There was a significant relationship between organization resource, organizational knowledge, process, management structure and values and goals with implementation of information technology. Findings showed that organizational factors had a considerable impact on implementation of information technology. Top managers must consider the important aspects of effective organizational factors.
ERIC Educational Resources Information Center
Anthony, Anika Ball
2012-01-01
Technology implementation research indicates that teachers' beliefs and knowledge, as well as a host of institutional factors, can influence technology integration. Drawing on third-generation activity theory, this article conceptualizes technology implementation as a network of planning and integration activities carried out by technology…
Teachers as Co-Designers of Technology-Rich Learning Activities for Early Literacy
ERIC Educational Resources Information Center
Cviko, Amina; McKenney, Susan; Voogt, Joke
2015-01-01
Although kindergarten teachers often struggle with implementing technology, they are rarely involved in co-designing technology-rich learning activities. This study involved teachers in the co-design of technology-rich learning activities and sought to explore implementation and pupil learning outcomes. A case-study method was used to investigate:…
ERIC Educational Resources Information Center
Shields-Bryant, Elayne
2006-01-01
The unprecedented growth, development and implementation of information technology (IT) driven by e-commerce and other technological advances have resulted in an increased demand of technology skilled workers (Reichgelt, Zhang, & Price, 2002; United States Department of Labor Bureau of Labor Statistics, 2005). In response to degree-dependent…
Gehring, Nicole D; McGrath, Patrick; Wozney, Lori; Soleimani, Amir; Bennett, Kathryn; Hartling, Lisa; Huguet, Anna; Dyson, Michele P; Newton, Amanda S
2017-06-21
Researchers, healthcare planners, and policymakers convey a sense of urgency in using eMental healthcare technologies to improve pediatric mental healthcare availability and access. Yet, different stakeholders may focus on different aspects of implementation. We conducted a systematic review to identify implementation foci in research studies and government/organizational documents for eMental healthcare technologies for pediatric mental healthcare. A search of eleven electronic databases and grey literature was conducted. We included research studies and documents from organization and government websites if the focus included eMental healthcare technology for children/adolescents (0-18 years), and implementation was studied and reported (research studies) or goals/recommendations regarding implementation were made (documents). We assessed study quality using the Mixed Methods Appraisal Tool and document quality using the Appraisal of Guidelines for Research & Evaluation II. Implementation information was grouped according to Proctor and colleagues' implementation outcomes-acceptability, adoption, appropriateness, cost, feasibility, fidelity, penetration, and sustainability-and grouped separately for studies and documents. Twenty research studies and nine government/organizational documents met eligibility criteria. These articles represented implementation of eMental healthcare technologies in the USA (14 studies), United Kingdom (2 documents, 3 studies), Canada (2 documents, 1 study), Australia (4 documents, 1 study), New Zealand (1 study), and the Netherlands (1 document). The quality of research studies was excellent (n = 11), good (n = 6), and poor (n = 1). These eMental health studies focused on the acceptability (70%, n = 14) and appropriateness (50%, n = 10) of eMental healthcare technologies to users and mental healthcare professionals. The quality of government and organizational documents was high (n = 2), medium (n = 6), and low (n = 1). These documents focused on cost (100%, n = 9), penetration (89%, n = 8), feasibility (78%, n = 7), and sustainability (67%, n = 6) of implementing eMental healthcare technology. To date, research studies have largely focused on acceptability and appropriateness, while government/organizational documents state goals and recommendations regarding costs, feasibility, and sustainability of eMental healthcare technologies. These differences suggest that the research evidence available for pediatric eMental healthcare technologies does not reflect the focus of governments and organizations. Partnerships between researchers, healthcare planners, and policymakers may help to align implementation research with policy development, decision-making, and funding foci.
Quantifying short run cost-effectiveness during a gradual implementation process.
van de Wetering, Gijs; Woertman, Willem H; Verbeek, Andre L; Broeders, Mireille J; Adang, Eddy M M
2013-12-01
This paper examines the short run inefficiencies that arise during gradual implementation of a new cost-effective technology in healthcare. These inefficiencies arise when health gains associated with the new technology cannot be obtained immediately because the new technology does not yet supply all patients, and when there is overcapacity for the old technology in the short run because the supply of care is divided among two mutually exclusive technologies. Such efficiency losses are not taken into account in standard textbook cost-effectiveness analysis in which a steady state is presented where costs and effects are assumed to be unchanging over time. A model is constructed to quantify such short run inefficiencies as well as to inform the decision maker about the optimal implementation pattern for the new technology. The model operates by integrating the incremental net benefit equations for both the period of co-existence of mutually exclusive technologies and the period after complete substitution of the old technology. It takes into account the rate of implementation of the new technology, depreciation of capital of the old technology as well as the demand curves for both technologies. The model is applied to the real world case of converting from screen film to digital mammography in the Netherlands.
Technology-Based Healthcare for Nursing Education Within The Netherlands: Past, Present and Future.
Koster, Ybranda; van Houwelingen, Cornelis T M
2017-01-01
At the present time, nearly all Dutch nursing schools are searching for suitable ways to implement technology-based healthcare in their curriculum. Some Universities chose elective education, others a mandatory solution. Several studies were executed to determine competencies needed by nurses in order to work with technology-based healthcare. In 2016 a nationwide new curriculum for nurses has been published. Providing technology-based healthcare is included under the core competencies of this new curriculum. All baccalaureate nursing educational institutes must implement this new curriculum at the start of 2016 which will have a huge impact on the implementation of technology-based healthcare in the education programs. In the future, technology centers from Universities will collaborate and specialize, partner with technology companies and crossovers between information and communication technology and healthcare education will be expanded.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-18
..., extension, and education programs on technology development and integrated research, extension, and education programs on technology implementation, in accordance with the purpose and priorities as described... the development, distribution, and implementation of biobased energy technologies; to promote...
Candidate Technologies for the Integrated Health Management Program
NASA Technical Reports Server (NTRS)
Johnson, Neal F., Jr.; Martin, Fred H.
1993-01-01
The purpose of this report is to assess Vehicle Health Management (VHM) technologies for implementation as a demonstration. Extensive studies have been performed to determine technologies which could be implemented on the Atlas and Centaur vehicles as part of a bridging program. This paper discusses areas today where VHM can be implemented for benefits in reliability, performance, and cost reduction. VHM Options are identified and one demonstration is recommended for execution.
Conditions That Facilitate the Implementation of Educational Technology Innovations.
ERIC Educational Resources Information Center
Ely, Donald P.
1990-01-01
Describes eight conditions that facilitate the adoption, implementation, and institutionalization of educational technology innovations and suggests applications to the transfer of portable software. Applications of these conditions involving educational technology in Indonesia, Chile, and Peru are evaluated, and guidelines for successful…
48 CFR 39.103 - Modular contracting.
Code of Federal Regulations, 2011 CFR
2011-10-01
... increments to take advantage of any evolution in technology or needs that occur during implementation and use... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.103 Modular contracting. (a) This section implements Section 5202, Incremental Acquisition of Information Technology, of the Clinger-Cohen...
48 CFR 39.103 - Modular contracting.
Code of Federal Regulations, 2013 CFR
2013-10-01
... increments to take advantage of any evolution in technology or needs that occur during implementation and use... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.103 Modular contracting. (a) This section implements Section 5202, Incremental Acquisition of Information Technology, of the Clinger-Cohen...
48 CFR 39.103 - Modular contracting.
Code of Federal Regulations, 2012 CFR
2012-10-01
... increments to take advantage of any evolution in technology or needs that occur during implementation and use... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.103 Modular contracting. (a) This section implements Section 5202, Incremental Acquisition of Information Technology, of the Clinger-Cohen...
Subspace aware recovery of low rank and jointly sparse signals
Biswas, Sampurna; Dasgupta, Soura; Mudumbai, Raghuraman; Jacob, Mathews
2017-01-01
We consider the recovery of a matrix X, which is simultaneously low rank and joint sparse, from few measurements of its columns using a two-step algorithm. Each column of X is measured using a combination of two measurement matrices; one which is the same for every column, while the the second measurement matrix varies from column to column. The recovery proceeds by first estimating the row subspace vectors from the measurements corresponding to the common matrix. The estimated row subspace vectors are then used to recover X from all the measurements using a convex program of joint sparsity minimization. Our main contribution is to provide sufficient conditions on the measurement matrices that guarantee the recovery of such a matrix using the above two-step algorithm. The results demonstrate quite significant savings in number of measurements when compared to the standard multiple measurement vector (MMV) scheme, which assumes same time invariant measurement pattern for all the time frames. We illustrate the impact of the sampling pattern on reconstruction quality using breath held cardiac cine MRI and cardiac perfusion MRI data, while the utility of the algorithm to accelerate the acquisition is demonstrated on MR parameter mapping. PMID:28630889
Lucantoni, Leonardo; Silvestrini, Francesco; Signore, Michele; Siciliano, Giulia; Eldering, Maarten; Dechering, Koen J.; Avery, Vicky M.; Alano, Pietro
2015-01-01
Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable of killing these forms are considered essential for the eradication of malaria and tools allowing the screening of large compound libraries with high predictive power are needed to identify new candidates. As gametocytes are not a replicative stage it is difficult to apply the same drug screening methods used for asexual stages. Here we propose an assay, based on high content imaging, combining “classic” gametocyte viability readout based on gametocyte counts with a functional viability readout, based on gametocyte activation and the discrimination of the typical gamete spherical morphology. This simple and rapid assay has been miniaturized to a 384-well format using acridine orange staining of wild type P. falciparum 3D7A sexual forms, and was validated by screening reference antimalarial drugs and the MMV Malaria Box. The assay demonstrated excellent robustness and ability to identify quality hits with high likelihood of confirmation of transmission reducing activity in subsequent mosquito membrane feeding assays. PMID:26553647
Barzekar, Hosein; Karami, Mahtab
2014-01-01
ABSTRACT Objective: to examine the organizational factors affecting the application of information technology in hospitals. Since the organizational factors are one of the most important determinants of successful projects, by understanding their impact and identifying them it can help planning a systematic IT implementation. Methods: In this cross-sectional descriptive study 110 middle managers were chosen from teaching hospitals. Structured questionnaire was used for the data collection. Results: There was a significant relationship between organization resource, organizational knowledge, process, management structure and values and goals with implementation of information technology. Conclusion: Findings showed that organizational factors had a considerable impact on implementation of information technology. Top managers must consider the important aspects of effective organizational factors. PMID:25568582
Factors influencing acceptance of technology for aging in place: a systematic review.
Peek, Sebastiaan T M; Wouters, Eveline J M; van Hoof, Joost; Luijkx, Katrien G; Boeije, Hennie R; Vrijhoef, Hubertus J M
2014-04-01
To provide an overview of factors influencing the acceptance of electronic technologies that support aging in place by community-dwelling older adults. Since technology acceptance factors fluctuate over time, a distinction was made between factors in the pre-implementation stage and factors in the post-implementation stage. A systematic review of mixed studies. Seven major scientific databases (including MEDLINE, Scopus and CINAHL) were searched. Inclusion criteria were as follows: (1) original and peer-reviewed research, (2) qualitative, quantitative or mixed methods research, (3) research in which participants are community-dwelling older adults aged 60 years or older, and (4) research aimed at investigating factors that influence the intention to use or the actual use of electronic technology for aging in place. Three researchers each read the articles and extracted factors. Sixteen out of 2841 articles were included. Most articles investigated acceptance of technology that enhances safety or provides social interaction. The majority of data was based on qualitative research investigating factors in the pre-implementation stage. Acceptance in this stage is influenced by 27 factors, divided into six themes: concerns regarding technology (e.g., high cost, privacy implications and usability factors); expected benefits of technology (e.g., increased safety and perceived usefulness); need for technology (e.g., perceived need and subjective health status); alternatives to technology (e.g., help by family or spouse), social influence (e.g., influence of family, friends and professional caregivers); and characteristics of older adults (e.g., desire to age in place). When comparing these results to qualitative results on post-implementation acceptance, our analysis showed that some factors are persistent while new factors also emerge. Quantitative results showed that a small number of variables have a significant influence in the pre-implementation stage. Fourteen out of the sixteen included articles did not use an existing technology acceptance framework or model. Acceptance of technology in the pre-implementation stage is influenced by multiple factors. However, post-implementation research on technology acceptance by community-dwelling older adults is scarce and most of the factors in this review have not been tested by using quantitative methods. Further research is needed to determine if and how the factors in this review are interrelated, and how they relate to existing models of technology acceptance. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.
2013-01-01
Background Information and communication technologies (ICTs) are often proposed as ‘technological fixes’ for problems facing healthcare. They promise to deliver services more quickly and cheaply. Yet research on the implementation of ICTs reveals a litany of delays, compromises and failures. Case studies have established that these technologies are difficult to embed in everyday healthcare. Methods We undertook an ethnographic comparative analysis of a single computer decision support system in three different settings to understand the implementation and everyday use of this technology which is designed to deal with calls to emergency and urgent care services. We examined the deployment of this technology in an established 999 ambulance call-handling service, a new single point of access for urgent care and an established general practice out-of-hours service. We used Normalization Process Theory as a framework to enable systematic cross-case analysis. Results Our data comprise nearly 500 hours of observation, interviews with 64 call-handlers, and stakeholders and documents about the technology and settings. The technology has been implemented and is used distinctively in each setting reflecting important differences between work and contexts. Using Normalisation Process Theory we show how the work (collective action) of implementing the system and maintaining its routine use was enabled by a range of actors who established coherence for the technology, secured buy-in (cognitive participation) and engaged in on-going appraisal and adjustment (reflexive monitoring). Conclusions Huge effort was expended and continues to be required to implement and keep this technology in use. This innovation must be understood both as a computer technology and as a set of practices related to that technology, kept in place by a network of actors in particular contexts. While technologies can be ‘made to work’ in different settings, successful implementation has been achieved, and will only be maintained, through the efforts of those involved in the specific settings and if the wider context continues to support the coherence, cognitive participation, and reflective monitoring processes that surround this collective action. Implementation is more than simply putting technologies in place – it requires new resources and considerable effort, perhaps on an on-going basis. PMID:23522021
NASA Astrophysics Data System (ADS)
Aldowah, Hanan; Ghazal, Samar; Naufal Umar, Irfan; Muniandy, Balakrishnan
2017-09-01
Information technology has achieved robust growth which has made it possible for learning to occur quickly. The rapid development of information, communication and technologies (ICT) has initiated an unparalleled transformation in universities all over the world. This development of technology and learning is offering new techniques to represent knowledge, new practices, and new global communities of learners. As a result, today’s economic and social changes force universities to try to find new learning approaches and systems. E-learning seems to be an appropriate approach in this aspect. However, the implementation of e-learning systems in universities is not an easy task because of some challenges related to context, technology, and other challenges. This paper studied the impacts of demographic data and reported the critical points for the decision makers to consider when planning and implementing e-learning in universities. A quantitative approach was used to study the effects of technological and contextual challenges on e-learning implementation in which a questionnaire was used for the data collection. According to the findings of the study, the most important challenges of the implementation of e-learning are related either to organizational (Contextual) and technological (technical) issues. The demographic variables have been found to play a direct and indirect role with the technological and contextual challenges of implementing e-learning. This paper showed that there are some significant differences in the two challenges faced by instructors in terms of the demographic variables. The result revealed that some significant differences exist between demographic variables and the two challenges of e-learning in terms of gender, age, teaching experience, ICT experience and e-learning experience. However, there is no significant difference in terms of e-learning experience. The obtained data, from such study, can provide information about what academic institutions can do before implementing e-learning to reduce and overcome the challenges in implementing e-learning in universities. So, university administrators interested in implementing e-learning should recognize the challenges that their instructors are facing and to provide the necessary policy and support to help overcome these challenges.
Grimm, Sabine E; Dixon, Simon; Stevens, John W
2017-07-01
With low implementation of cost-effective health technologies being a problem in many health systems, it is worth considering the potential effects of research on implementation at the time of health technology assessment. Meaningful and realistic implementation estimates must be of dynamic nature. To extend existing methods for assessing the value of research studies in terms of both reduction of uncertainty and improvement in implementation by considering diffusion based on expert beliefs with and without further research conditional on the strength of evidence. We use expected value of sample information and expected value of specific implementation measure concepts accounting for the effects of specific research studies on implementation and the reduction of uncertainty. Diffusion theory and elicitation of expert beliefs about the shape of diffusion curves inform implementation dynamics. We illustrate use of the resulting dynamic expected value of research in a preterm birth screening technology and results are compared with those from a static analysis. Allowing for diffusion based on expert beliefs had a significant impact on the expected value of research in the case study, suggesting that mistakes are made where static implementation levels are assumed. Incorporating the effects of research on implementation resulted in an increase in the expected value of research compared to the expected value of sample information alone. Assessing the expected value of research in reducing uncertainty and improving implementation dynamics has the potential to complement currently used analyses in health technology assessments, especially in recommendations for further research. The combination of expected value of research, diffusion theory, and elicitation described in this article is an important addition to the existing methods of health technology assessment.
de Boer, I R; Bakker, D R; Serrano, C M; Koopman, P; Wesselink, P R; Vervoorn, J M
2018-03-01
This study outlines an approach for education innovation and addresses the ambivalence between evidence-based and non-evidence-based conditions. The "on-the-fly" approach was described as involving implementation during the development of an innovation for dental education. The process of designing and implementing cutting-edge technology of the MOOG Simodont Dental Trainer (DT) whilst systematically collecting evidence illustrates the "on-the-fly" approach. Using the "on-the-fly" approach for developing, implementing and collecting evidence simultaneously in an academic environment appears feasible in serving both the professionals, users and developers and system designers. During the implementation of the new technology, growing evidence stepwise strengthened its position; therefore, showing stakeholders that evidence was used to improve the technology seemed to support and increase acceptance of the new technology. When pioneering an innovative technology in a specialty field, the development stage often precedes evidence for its effectiveness. Consciously choosing the "on-the-fly" approach clarifies to stakeholders in advance about the lack of evidence in an innovation and the need of their support to collect such evidence for improvement and in order to facilitate implementation. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Nilsen, Etty R; Dugstad, Janne; Eide, Hilde; Gullslett, Monika Knudsen; Eide, Tom
2016-11-15
Industrialized and welfare societies are faced with vast challenges in the field of healthcare in the years to come. New technological opportunities and implementation of welfare technology through co-creation are considered part of the solution to this challenge. Resistance to new technology and resistance to change is, however, assumed to rise from employees, care receivers and next of kin. The purpose of this article is to identify and describe forms of resistance that emerged in five municipalities during a technology implementation project as part of the care for older people. This is a longitudinal, single-embedded case study with elements of action research, following an implementation of welfare technology in the municipal healthcare services. Participants included staff from the municipalities, a network of technology developers and a group of researchers. Data from interviews, focus groups and participatory observation were analysed. Resistance to co-creation and implementation was found in all groups of stakeholders, mirroring the complexity of the municipal context. Four main forms of resistance were identified: 1) organizational resistance, 2) cultural resistance, 3) technological resistance and 4) ethical resistance, each including several subforms. The resistance emerges from a variety of perceived threats, partly parallel to, partly across the four main forms of resistance, such as a) threats to stability and predictability (fear of change), b) threats to role and group identity (fear of losing power or control) and c) threats to basic healthcare values (fear of losing moral or professional integrity). The study refines the categorization of resistance to the implementation of welfare technology in healthcare settings. It identifies resistance categories, how resistance changes over time and suggests that resistance may play a productive role when the implementation is organized as a co-creation process. This indicates that the importance of organizational translation between professional cultures should not be underestimated, and supports research indicating that focus on co-initiation in the initial phase of implementation projects may help prevent different forms of resistance in complex co-creation processes.
Implementing Computer Technologies: Teachers' Perceptions and Practices
ERIC Educational Resources Information Center
Wozney, Lori; Venkatesh, Vivek; Abrami, Philip
2006-01-01
This study investigates personal and setting characteristics, teacher attitudes, and current computer technology practices among 764 elementary and secondary teachers from both private and public school sectors in Quebec. Using expectancy-value theory, the Technology Implementation Questionnaire (TIQ) was developed; it consists of 33 belief items…
Lord, Sarah; Moore, Sarah K; Ramsey, Alex; Dinauer, Susan; Johnson, Kimberly
2016-06-28
Research supports the effectiveness of technology-based treatment approaches for substance use disorders. These approaches have the potential to broaden the reach of evidence-based care. Yet, there is limited understanding of factors associated with implementation of technology-based care approaches in different service settings. In this study, we explored provider and staff perceptions of facilitators and barriers to implementation of a mobile phone substance use recovery support app with clients in 4 service settings. Interviews were conducted with leadership and provider stakeholders (N=12) from 4 agencies in the first year of an implementation trial of the mobile phone app. We used the Consolidated Framework for Implementation Research as the conceptual foundation for identifying facilitators and barriers to implementation. Implementation process facilitators included careful planning of all aspects of implementation before launch, engaging a dedicated team to implement and foster motivation, working collaboratively with the app development team to address technical barriers and adapt the app to meet client and agency needs, and consistently reviewing app usage data to inform progress. Implementation support strategies included training all staff to promote organization awareness about the recovery support app and emphasize its priority as a clinical care tool, encouraging clients to try the technology before committing to use, scaling rollout to clients, setting clear expectations with clients about use of the app, and using peer coaches and consistent client-centered messaging to promote engagement. Perceived compatibility of the mobile phone app with agency and client needs and readiness to implement emerged as salient agency-level implementation facilitators. Facilitating characteristics of the recovery support app itself included evidence of its impact for recovery support, perceived relative advantage of the app over usual care, the ability to adapt the app to improve client use, and its ease of use. The mobile phone itself was a strong motivation for clients to opt in to use the app in settings that provided phones. App access was limited in settings that did not provide phones owing to lack of mobile phone ownership or incompatibility of the app with clients' mobile phones. Individual differences in technology literacy and provider beliefs about substance use care either facilitated or challenged implementation. Awareness of patient needs and resources facilitated implementation, whereas external policies and regulations regarding technology use introduced barriers to implementation. The conceptually grounded facilitators and barriers identified in this study can guide systematic targeting of strategies to improve implementation of mobile phone interventions in community treatment settings. Results also inform the design of technology-based therapeutic tools. This study highlights directions for research with regard to implementation of technology-based behavioral health care approaches.
Moore, Sarah K; Ramsey, Alex; Dinauer, Susan; Johnson, Kimberly
2016-01-01
Background Research supports the effectiveness of technology-based treatment approaches for substance use disorders. These approaches have the potential to broaden the reach of evidence-based care. Yet, there is limited understanding of factors associated with implementation of technology-based care approaches in different service settings. Objectives In this study, we explored provider and staff perceptions of facilitators and barriers to implementation of a mobile phone substance use recovery support app with clients in 4 service settings. Methods Interviews were conducted with leadership and provider stakeholders (N=12) from 4 agencies in the first year of an implementation trial of the mobile phone app. We used the Consolidated Framework for Implementation Research as the conceptual foundation for identifying facilitators and barriers to implementation. Results Implementation process facilitators included careful planning of all aspects of implementation before launch, engaging a dedicated team to implement and foster motivation, working collaboratively with the app development team to address technical barriers and adapt the app to meet client and agency needs, and consistently reviewing app usage data to inform progress. Implementation support strategies included training all staff to promote organization awareness about the recovery support app and emphasize its priority as a clinical care tool, encouraging clients to try the technology before committing to use, scaling rollout to clients, setting clear expectations with clients about use of the app, and using peer coaches and consistent client-centered messaging to promote engagement. Perceived compatibility of the mobile phone app with agency and client needs and readiness to implement emerged as salient agency-level implementation facilitators. Facilitating characteristics of the recovery support app itself included evidence of its impact for recovery support, perceived relative advantage of the app over usual care, the ability to adapt the app to improve client use, and its ease of use. The mobile phone itself was a strong motivation for clients to opt in to use the app in settings that provided phones. App access was limited in settings that did not provide phones owing to lack of mobile phone ownership or incompatibility of the app with clients’ mobile phones. Individual differences in technology literacy and provider beliefs about substance use care either facilitated or challenged implementation. Awareness of patient needs and resources facilitated implementation, whereas external policies and regulations regarding technology use introduced barriers to implementation. Conclusions The conceptually grounded facilitators and barriers identified in this study can guide systematic targeting of strategies to improve implementation of mobile phone interventions in community treatment settings. Results also inform the design of technology-based therapeutic tools. This study highlights directions for research with regard to implementation of technology-based behavioral health care approaches. PMID:27352884
Burnishing Systems: a Short Survey of the State-of-the-art
NASA Astrophysics Data System (ADS)
Bobrovskij, I. N.
2018-01-01
The modern technological solutions allowing to implement a new technology of surface plastic deformation are considered. The technological device allowing to implement the technology of hyper productive surface plastic deformation or wide burnishing (machining time is up to 2-3 revolutions of workpiece) is presented. The device provides the constant force of instruments regardless the beating, non-roundness and other surface shape defects; usable and easily controlled force adjustment; precise installation of instruments and holders toward the along the worpieces axis; automation of the supply and retraction of instruments. Also the device allowing to implement the technology of nanostructuring burnishing is presented. The design of the device allows to eliminate the effect of auto-oscillations.
ERIC Educational Resources Information Center
Sawtelle, Sara
2008-01-01
Proving that technology works is not as simple as proving that a new vendor for art supplies is more cost effective. Technology effectiveness requires both the right software and the right implementation. Just having the software is not enough. Proper planning, training, leadership, support, pedagogy, and software use--along with many other…
ERIC Educational Resources Information Center
Barri, Moatasim A.
2013-01-01
There are a number of factors that influence technology implementation in the classroom including teachers' concerns; barriers; and intrinsic incentives. These factors give classroom teachers a chance to make a shift in their thinking and practice to help them properly integrate technology across the curriculum. This study was designed to assess:…
USDA-ARS?s Scientific Manuscript database
The Chesapeake Stormwater Network hosted a workshop on July, 2012 to discuss the potential nutrient reductions from emerging stormwater technologies including algal flow-way technologies (AFTs). Workshop participants recommended the Chesapeake Bay Program’s Water Quality Goal Implementation Team(WQ...
The acceptance of green technology: A case study in Sabah Development Corridor
NASA Astrophysics Data System (ADS)
Jainudin, Noor Azland; Jugah, Ivy; Ali, Awang Nasrizal Awang; Tawie, Rudy
2017-08-01
Green technology is the development and application of products, equipment and systems used to conserve the environment which minimizes the negative impact from human activities. The technology can be in the form of green buildings or renewable energy such as hydro, solar and biogas. Development in SDC is still at the early stage, hence there is a prospect to plan for proper green concept implementation. With the increasing number of construction projects particularly in the rapid developing city of Kota Kinabalu, green technology as a whole is becoming more significant as it helps to develop effective solutions to encounter global environmental issues. Although there has been lengthy discussion on the green technology, the visibility of the implementation is still yet to be seen widely in Kota Kinabalu. The implementation of green technology in construction will support dynamic growth of economic development activities, while improving the environment. Hence, it is important to develop a strategic plan to promote the use of green technology while the areas are still developing. The focus of this correlative-based approach study is to investigate the perception and implementation of green technology in Kota Kinabalu from the industrial perspectives.
Incommensurate Practices: Sociomaterial Entanglements of Learning Technology Implementation
ERIC Educational Resources Information Center
Hannon, J.
2013-01-01
The framing of "implementation" of learning technologies in universities can have profound effects on approaches to teaching and learning that may be insufficiently acknowledged by practitioners. This paper investigates a case that demonstrated the formation of strong connections between technology and pedagogy, in which a learning…
Learning Generation: Fostering Innovation with Tomorrow's Teachers and Technology
ERIC Educational Resources Information Center
Aust, Ronald; Newberry, Brian; O'Brien, Joseph; Thomas, Jennifer
2005-01-01
We discuss the context, conception, implementation, and research used to refine and evaluate a systemic model for fostering technology integration in teacher education. The Learning Generation model identifies conditions where innovations for using technology emerge in small group dialogues. The model uses a multifaceted implementation with…
Development and Implementation of Culturally Tailored Offline Mobile Health Surveys.
McIntosh, Scott; Pérez-Ramos, José; Demment, Margaret M; Vélez Vega, Carmen; Avendaño, Esteban; Ossip, Deborah J; Dye, Timothy D
2016-06-02
In low and middle income countries (LMICs), and other areas with low resources and unreliable access to the Internet, understanding the emerging best practices for the implementation of new mobile health (mHealth) technologies is needed for efficient and secure data management and for informing public health researchers. Innovations in mHealth technology can improve on previous methods, and dissemination of project development details and lessons learned during implementation are needed to provide lessons learned to stakeholders in both the United States and LMIC settings. The aims of this paper are to share implementation strategies and lessons learned from the development and implementation stages of two survey research projects using offline mobile technology, and to inform and prepare public health researchers and practitioners to implement new mobile technologies in survey research projects in LMICs. In 2015, two survey research projects were developed and piloted in Puerto Rico and pre-tested in Costa Rica to collect face-to-face data, get formative evaluation feedback, and to test the feasibility of an offline mobile data collection process. Fieldwork in each setting involved survey development, back translation with cultural tailoring, ethical review and approvals, data collector training, and piloting survey implementation on mobile tablets. Critical processes and workflows for survey research projects in low resource settings were identified and implemented. This included developing a secure mobile data platform tailored to each survey, establishing user accessibility, and training and eliciting feedback from data collectors and on-site LMIC project partners. Formative and process evaluation strategies are necessary and useful for the development and implementation of survey research projects using emerging mHealth technologies in LMICs and other low resource settings. Lessons learned include: (1) plan institutional review board (IRB) approvals in multiple countries carefully to allow for development, implementation, and feedback, (2) in addition to testing the content of survey instruments, allow time and consideration for testing the use of novel mHealth technology (hardware and software), (3) incorporate training for and feedback from project staff, LMIC partner staff, and research participants, and (4) change methods accordingly, including content, as mHealth technology usage influences and is influenced by the content and structure of the survey instrument. Lessons learned from early phases of LMIC research projects using emerging mHealth technologies are critical for informing subsequent research methods and study designs.
Practicing Technology Implementation: The Case of an Enterprise System
ERIC Educational Resources Information Center
Awazu, Yukika
2013-01-01
Drawing on four theories of practice--Communities of Practice (CoP), Bourdieu's theory of practice, Pickering's mangle of practice, and Actor Network Theory (ANT), the study provides an in-depth understanding about technology implementation practice. Analysis of an Enterprise System implementation project in a software manufacturing…
1997-05-01
INNOVATION MARINE INDUSTRY STANDARDS WELDING INDUSTRIAL ENGINEERING EDUCATION AND TRAINING THE NATIONAL SHIPBUILDING RESEARCH PROGRAM May 1, 1997 NSRP 0495...Report on Short Course on: Implementation of Zone Technology in the Repair and Overhaul Environment U.S. DEPARTMENT OF THE NAVY CARDEROCK DIVISION...COVERED - 4. TITLE AND SUBTITLE The National Shipbuilding Research Program, Report on Short Course on: Implementation of Zone Technology in the
Approaching hospital administration about adopting cooling technologies.
Kirkland, Lisa L; Parham, William M; Pastores, Stephen M
2009-07-01
The purpose of this article is to provide intensivists with information and examples regarding cooling technology selection, cost assessment, adaptation, barriers, and presentation to hospital administrators. A review of medical and business literature was conducted using the following search terms: technology assessment, organizational innovation, intensive care, critical care, hospital administration, and presentation to administrators. General recommendations for intensivists are made for assessing cooling technology with descriptions of common new technology implementation stages. A study of 16 hospitals implementing a new cardiac surgery technology is described. A description of successful implementation of an induced hypothermia protocol by one of the authors is presented. Although knowledgeable about the applications of new technologies, including cooling technology, intensivists have little guidance or training on tactics to obtain a hospital administration's funding and support. Intensive care unit budgets are usually controlled by nonintensivists whose interests are neutral, at best, to the needs of intensivists. To rise to the top of the large pile of requisition requests, an intensivist's proposal must be well conceived and aligned with hospital administration's strategic goals. Intensivists must understand the hospital acquisition process and administrative structure and participate on high-level hospital committees. Using design thinking and strong leadership skills, the intensivist can marshal support from staff and administrators to successfully implement cooling technology.
A Senior Teacher's Implementation of Technology Integration
ERIC Educational Resources Information Center
Tsai, Hsien-Chang
2015-01-01
This study investigated whether a senior teacher with many years of teaching experience, despite lacking adequate technology skills or contending with other barriers, can sufficiently implement technology integration in the classroom. The research was conducted between October 2013 and January 2014 and was focused on a junior high school biology…
The Implementation of Web Conferencing Technologies in Online Graduate Classes
ERIC Educational Resources Information Center
Zotti, Robert
2017-01-01
This dissertation examines the implementation of web conferencing technology in online graduate courses within management, engineering, and computer science programs. Though the spread of learning management systems over the past two decades has been dramatic, the use of web conferencing technologies has curiously lagged. The real-time…
ERIC Educational Resources Information Center
Nolin, Anna P.
2014-01-01
This study explored the role of professional learning communities for district leadership implementing large-scale technology initiatives such as 1:1 implementations (one computing device for every student). The existing literature regarding technology leadership is limited, as is literature on how districts use existing collaborative structures…
Assistive Technology Instruction within a Continuously Evolving Technology Environment
ERIC Educational Resources Information Center
Peterson-Karlan, George R.
2015-01-01
The movement toward greater availability of online education in the university setting creates challenges for design, development, and implementation of online courses, particularly those focused on the educational use of technology as content. This article is structured around a central theme of designing and implementing hybrid online courses…
A Model for Pedagogical and Curricula Transformation with Technology.
ERIC Educational Resources Information Center
Wetzel, David R.
The purpose of this study was to investigate the factors that influenced five middle school science teachers as they implemented and integrated instructional technology in their curricula, along with determining the effects that implementation and integration of instructional technology had on their pedagogy and curricula. The study involved…
The integration of technology into the middle and high school science curriculum
NASA Astrophysics Data System (ADS)
Corbin, Jan Frederic
This study was to determine the level of technology implementation into the middle and high school science curriculum by beginning teachers. Research was conducted in two phases. The first phase was a survey that provided demographic data and determined the Level of Technology Implementation, Personal Computer Use, and Current Instructional Practice. Dr. Christopher Moersch developed the survey, Level of Technology Implementation (LoTi(c) ). The data provided insight into what technology teachers use, barriers associated with technology integration, teacher training and development, and technical support. Follow-up interviews were conducted to gather additional qualitative data and information. Analysis of the data found beginning teachers have not received enough technology training to integrate technology seamlessly into the science curriculum. Conclusions cite the need for more technology courses during preservice education, more time during the day for beginning teachers to learn to use the technology available at their schools, consolidation of inservice staff development offerings, and more technical support staff readily available. Recommendations were made to expand the study group to all science teachers, assess the technology capacity of all schools, and conduct needs assessment of inservice staff development.
Strategies from a nationwide health information technology implementation: the VA CART story.
Box, Tamára L; McDonell, Mary; Helfrich, Christian D; Jesse, Robert L; Fihn, Stephan D; Rumsfeld, John S
2010-01-01
The VA Cardiovascular Assessment, Reporting, and Tracking (CART) system is a customized electronic medical record system which provides standardized report generation for cardiac catheterization procedures, serves as a national data repository, and is the centerpiece of a national quality improvement program. Like many health information technology projects, CART implementation did not proceed without some barriers and resistance. We describe the nationwide implementation of CART at the 77 VA hospitals which perform cardiac catheterizations in three phases: (1) strategic collaborations; (2) installation; and (3) adoption. Throughout implementation, success required a careful balance of technical, clinical, and organizational factors. We offer strategies developed through CART implementation which are broadly applicable to technology projects aimed at improving the quality, reliability, and efficiency of health care.
Information Technology Diffusion: A Comparative Case Study of Intranet Adoption
1999-07-01
Information Technology Diffusion: A Comparative Case Study of Intranet Adoption George A. Zolla Jr. Naval Postgraduate School, Monterey, CA 93943...and diffusion of intranet technology is then presented. I. INTRODUCTION An intranet is an organization’s internal computer network protected from the... Information Systems (IS) strategy links to implementation [16]. More research dealing with the implementation of new technology in organizations is needed
ERIC Educational Resources Information Center
National Coordination Office for Information Technology Research and Development, Arlington, VA.
As a part of its ongoing mission, the President's Information Technology Advisory Committee (PITAC) has completed an initial review of the Information Technology for the 21st Century (IT[squared]) initiative and its implementation plan put forward by the participating federal agencies. This letter conveys the initial conclusions of that review.…
Pharmacogenomic technologies: a necessary "luxury" for better global public health?
2011-01-01
Background Pharmacogenomic technologies aim to redirect drug development to increase safety and efficacy of individual care. There is much hope that their implementation in the drug development process will help respond to population health needs, particularly in developing countries. However, there is also fear that novel pharmacogenomic drugs will remain too costly, be designed for the needs of the wealthy nations, and so constitute an unnecessary "luxury" for most populations. In this paper, we analyse the promise that pharmacogenomic technologies hold for improving global public health and identify strategies and challenges associated with their implementation. Discussion This paper evaluates the capacity of pharmacogenomic technologies to meet six criteria described by the University of Toronto Joint Centre for Bioethics group: 1) impact of the technology, 2) technology appropriateness, 3) capacity to address local burdens, 4) feasibility to be implemented in reasonable time, 5) capacity to reduce the knowledge gap, and 6) capacity for indirect benefits. We argue that the implementation of pharmacogenomic technologies in the drug development process can positively impact population health. However, this positive impact depends on how and for which purposes the technologies are used. We discuss the potential of these technologies to stimulate drug discovery in the case of rare (orphan diseases) or neglected diseases, but also to reduce acute adverse drug reactions in infectious disease treatment and prevention, which promises to improve global public health. Conclusions The implementation of pharmacogenomic technologies may lead to the development of drugs that appear to be a "luxury" for populations in need of numerous interventions that are known to have a demonstrable impact on population health (e.g., secure access to potable water, reduction of social inequities, health education). However, our analysis shows that pharmacogenomic technologies do have the potential to redirect drug development and distribution so as to improve the health of vulnerable populations. Strategies should thus be developed to better direct their implementation towards meeting the needs and responding to the realities of populations of the developing world (i.e., social, cultural and political acceptability, and local health burdens), making pharmacogenomic technologies a necessary "luxury" for global public health. PMID:21864366
Horban', A Ie
2013-09-01
The question of implementation of the state policy in the field of technology transfer in the medical branch to implement the law of Ukraine of 02.10.2012 No 5407-VI "On Amendments to the law of Ukraine" "On state regulation of activity in the field of technology transfers", namely to ensure the formation of branch database on technology and intellectual property rights owned by scientific institutions, organizations, higher medical education institutions and enterprises of healthcare sphere of Ukraine and established by budget are considered. Analysis of international and domestic experience in the processing of information about intellectual property rights and systems implementation support transfer of new technologies are made. The main conceptual principles of creation of this branch database of technology transfer and branch technology transfer network are defined.
Botha-Ravyse, Chrisna; Blignaut, Seugnet
2017-01-01
Early adoption of technology is a struggle well known to early adopters and now to me. Since the demand to use and implement technology in health professions' education has increased, I have been led to adopt various technologies, leading to many headaches. This paper addresses my experiences in developing and implementing technology in health science classrooms in a setting not adequately equipped to do so. After reflecting on my experiences, I conclude that it is crucial that systems help innovators and early adopters as they work to develop and implement teaching and learning technology. Technical decisions should address the needs of the higher education educator. In addition, once an institution chooses a specific technological approach, such as using e-guides, there should be resources in place to support the forerunners of these initiatives.
SCAR Radiologic Technologist Survey: analysis of the impact of digital technologies on productivity.
Reiner, Bruce I; Siegel, Eliot L; Carrino, John A; Goldburgh, Mitchell M
2002-09-01
As medical reimbursements continue to decline, increasing financial pressures are placed upon medical imaging providers. This burden is exacerbated by the existing radiologic technologist (RT) crisis, which has caused RT salaries to trend upward. One strategy to address these trends is employing technology to improve technologist productivity. While industry-wide RT productivity benchmarks have been established for film-based operation, little to date has been published in the medical literature regarding similar productivity measures for filmless operation using PACS. This study was undertaken to document the complex relationship between technologist productivity and implementation of digital radiography and digital information technologies, including PACS and hospital/radiology information systems (HIS/RIS). A nationwide survey was conducted with 112 participating institutions, in varying degrees of digital technology implementation. Technologist productivity was defined as the number of annual exams performed per technologist full-time equivalent (FTE). Productivity analyses were performed among the different demographic and technology profile groups, with a focus on general radiography, which accounts for 65-70% of imaging department volumes. When evaluating the relationship between technologist productivity and digital technology implementation, improved productivity measures were observed for institutions implementing HIS/RIS, modality worklist, and PACS. The timing of PACS implementation was found to have a significant effect on technologist productivity measures, with an initial 10.8% drop in productivity during the first year of PACS implementation, followed by a 27.8% increase in productivity beyond year one. This suggests there is a "PACS learning curve" phenomenon, which should be considered when institutions are planning for PACS implementation.
Self-Brown, Shannon R; C Osborne, Melissa; Rostad, Whitney; Feil, Ed
2017-11-01
Implementation of evidence-based parenting programs is critical for parents at-risk for child maltreatment perpetration; however, widespread use of effective programs is limited in both child welfare and prevention settings. This exploratory study sought to examine whether a technology-mediated approach to SafeCare ® delivery can feasibly assist newly trained providers in achieving successful implementation outcomes. Thirty-one providers working in child welfare or high-risk prevention settings were randomized to either SafeCare Implementation with Technology-Assistance (SC-TA) or SafeCare Implementation as Usual (SC-IU). SC-TA providers used a web-based program during session that provided video-based psychoeducation and modeling directly to parents and overall session guidance to providers. Implementation outcome data were collected from providers for six months. Data strongly supported the feasibility of SC-TA. Further, data indicated that SC-TA providers spent significantly less time on several activities in preparation, during, and in follow-up to SafeCare sessions compared to SC-IU providers. No differences were found between the groups with regard to SafeCare fidelity and certification status. Findings suggest that technology can augment implementation by reducing the time and training burden associated with implementing new evidence-based practices for at-risk families.
Implementation of RFID Technology in University of Pune Library
ERIC Educational Resources Information Center
Bansode, Sadanand Y.; Desale, Sanjay K.
2009-01-01
Purpose: The purpose of this paper is to describe the implementation of a radio frequency identification (RFID) system in Pune University Library. Design/methodology/approach: The paper provides a brief overview of background of the project, barriers faced and changes that have been experienced after the implementation of the technology. Findings:…
Pros and cons of healthcare information technology implementation: the pros win.
Maffei, Roxana
2006-01-01
Countless studies and investigations have been performed siding either for or against the implementation of technology in the healthcare setting. This article presents both sides of this debate, with an obvious conclusion that the pros of this debate win. The practice of information technology in the medical domain lags behind its knowledge and discovery by at least 7 years. The key to closing this gap is to show, through various studies, how information technology systems provide decision support to users at the point in time when decisions are needed. What the reader will obtain from this article is that the pros for information technology implementation in healthcare settings weigh much more and have a greater effect than the cons.
Implementing technology to improve medication safety in healthcare facilities: a literature review.
Hidle, Unn
Medication errors remain one of the most common causes of patient injuries in the United States, with detrimental outcomes including adverse reactions and even death. By developing a better understanding of why and how medication errors occur, preventative measures may be implemented including technological advances. In this literature review, potential methods of reducing medication errors were explored. Furthermore, technology tools available for medication orders and administration are described, including advantages and disadvantages of each system. It was found that technology can be an excellent aid in improving safety of medication administration. However, computer technology cannot replace human intellect and intuition. Nurses should be involved when implementing any new computerized system in order to obtain the most appropriate and user-friendly structure.
The Efficacy of Psychophysiological Measures for Implementing Adaptive Technology
NASA Technical Reports Server (NTRS)
Scerbo, Mark W.; Freeman, Frederick G.; Mikulka, Peter J.; Parasuraman, Raja; DiNocero, Francesco; Prinzel, Lawrence J., III
2001-01-01
Adaptive automation refers to technology that can change its mode of operation dynamically. Further, both the technology and the operator can initiate changes in the level or mode of automation. The present paper reviews research on adaptive technology. It is divided into three primary sections. In the first section, issues surrounding the development and implementation of adaptive automation are presented. Because physiological-based measures show much promise for implementing adaptive automation, the second section is devoted to examining candidate indices. In the final section, those techniques that show the greatest promise for adaptive automation as well as issues that still need to be resolved are discussed.
2014-01-01
Background Healthcare reform in the United States is encouraging Federally Qualified Health Centers and other primary-care practices to integrate treatment for addiction and other behavioral health conditions into their practices. The potential of mobile health technologies to manage addiction and comorbidities such as HIV in these settings is substantial but largely untested. This paper describes a protocol to evaluate the implementation of an E-Health integrated communication technology delivered via mobile phones, called Seva, into primary-care settings. Seva is an evidence-based system of addiction treatment and recovery support for patients and real-time caseload monitoring for clinicians. Methods/Design Our implementation strategy uses three models of organizational change: the Program Planning Model to promote acceptance and sustainability, the NIATx quality improvement model to create a welcoming environment for change, and Rogers’s diffusion of innovations research, which facilitates adaptations of innovations to maximize their adoption potential. We will implement Seva and conduct an intensive, mixed-methods assessment at three diverse Federally Qualified Healthcare Centers in the United States. Our non-concurrent multiple-baseline design includes three periods — pretest (ending in four months of implementation preparation), active Seva implementation, and maintenance — with implementation staggered at six-month intervals across sites. The first site will serve as a pilot clinic. We will track the timing of intervention elements and assess study outcomes within each dimension of the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework, including effects on clinicians, patients, and practices. Our mixed-methods approach will include quantitative (e.g., interrupted time-series analysis of treatment attendance, with clinics as the unit of analysis) and qualitative (e.g., staff interviews regarding adaptations to implementation protocol) methods, and assessment of implementation costs. Discussion If implementation is successful, the field will have a proven technology that helps Federally Qualified Health Centers and affiliated organizations provide addiction treatment and recovery support, as well as a proven strategy for implementing the technology. Seva also has the potential to improve core elements of addiction treatment, such as referral and treatment processes. A mobile technology for addiction treatment and accompanying implementation model could provide a cost-effective means to improve the lives of patients with drug and alcohol problems. Trial registration ClinicalTrials.gov (NCT01963234). PMID:24884976
Quanbeck, Andrew R; Gustafson, David H; Marsch, Lisa A; McTavish, Fiona; Brown, Randall T; Mares, Marie-Louise; Johnson, Roberta; Glass, Joseph E; Atwood, Amy K; McDowell, Helene
2014-05-29
Healthcare reform in the United States is encouraging Federally Qualified Health Centers and other primary-care practices to integrate treatment for addiction and other behavioral health conditions into their practices. The potential of mobile health technologies to manage addiction and comorbidities such as HIV in these settings is substantial but largely untested. This paper describes a protocol to evaluate the implementation of an E-Health integrated communication technology delivered via mobile phones, called Seva, into primary-care settings. Seva is an evidence-based system of addiction treatment and recovery support for patients and real-time caseload monitoring for clinicians. Our implementation strategy uses three models of organizational change: the Program Planning Model to promote acceptance and sustainability, the NIATx quality improvement model to create a welcoming environment for change, and Rogers's diffusion of innovations research, which facilitates adaptations of innovations to maximize their adoption potential. We will implement Seva and conduct an intensive, mixed-methods assessment at three diverse Federally Qualified Healthcare Centers in the United States. Our non-concurrent multiple-baseline design includes three periods - pretest (ending in four months of implementation preparation), active Seva implementation, and maintenance - with implementation staggered at six-month intervals across sites. The first site will serve as a pilot clinic. We will track the timing of intervention elements and assess study outcomes within each dimension of the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework, including effects on clinicians, patients, and practices. Our mixed-methods approach will include quantitative (e.g., interrupted time-series analysis of treatment attendance, with clinics as the unit of analysis) and qualitative (e.g., staff interviews regarding adaptations to implementation protocol) methods, and assessment of implementation costs. If implementation is successful, the field will have a proven technology that helps Federally Qualified Health Centers and affiliated organizations provide addiction treatment and recovery support, as well as a proven strategy for implementing the technology. Seva also has the potential to improve core elements of addiction treatment, such as referral and treatment processes. A mobile technology for addiction treatment and accompanying implementation model could provide a cost-effective means to improve the lives of patients with drug and alcohol problems. ClinicalTrials.gov (NCT01963234).
ERIC Educational Resources Information Center
Center for Educational Leadership and Technology, Inc., Marlborough, MA.
This document presents guidelines and recommendations for development of a technology infrastructure in Connecticut public schools that conforms to national industry standards for voice, video, and data communications. The guidelines present information on the state statutes regarding facilities implementation and describe industry standards.…
The Implementation of Technology-Based SME Management Development Programmes
ERIC Educational Resources Information Center
Carr, James
2005-01-01
Learning technology is seen as one solution to the problem of delivering management training in Small and Medium-sized Enterprises (SMEs). This paper investigates how the Higher Education (HE) sector can use its growing expertise in learning technology implementation to develop effective SME management development solutions. It is found that there…
ERIC Educational Resources Information Center
Dockum, James R.
2009-01-01
It was the purpose of this study to determine teacher perceptions of the effective implementation of interactive technologies in one Virginia middle school. The questions that guided this study were the following: What are the Virginia middle school teachers' perceptions of effective integration of interactive technologies? Specifically: What are…
Towards a Resilient Strategy for Technology-Enhanced Learning
ERIC Educational Resources Information Center
Hall, Richard
2011-01-01
Purpose: This paper sets out to argue that the strategic implementation of technology is implicated in a range of crises or socio-economic disruptions, like peak oil, climate change and the rising environmental costs of energy consumption. It aims to argue that institutional technological implementation is contested, complex and should not be…
ERIC Educational Resources Information Center
Jimoyiannis, Athanassios
2010-01-01
This paper reports on the design and the implementation of the Technological Pedagogical Science Knowledge (TPASK), a new model for science teachers professional development built on an integrated framework determined by the Technological Pedagogical Content Knowledge (TPACK) model and the authentic learning approach. The TPASK curriculum…
E-Laboratory Design and Implementation for Enhanced Science, Technology and Engineering Education
ERIC Educational Resources Information Center
Morton, William; Uhomoibhi, James
2011-01-01
Purpose: This paper aims to report on the design and implementation of an e-laboratory for enhanced science, technology and engineering education studies. Design/methodology/approach: The paper assesses a computer-based e-laboratory, designed for new entrants to science, technology and engineering programmes of study in further and higher…
ERIC Educational Resources Information Center
Behravesh, Bardia
2010-01-01
The United States continues to lag behind other countries in its adoption of health information technology. A failure to increase adoption will jeopardize the nation's ability to reduce medical errors, address the rapid growth of healthcare costs, and enact effective healthcare reform. Health information technology (HIT) implementation success…
Enterprise Social Networking: Technology Acceptance Related to Personality, Age, and Gender
ERIC Educational Resources Information Center
Rochelle, Joseph
2017-01-01
In this dissertation, the researcher examined and added to the body of knowledge within the project change management field of technology implementation. The rationale behind the study was to evaluate technology acceptance of Enterprise Social Networking (ESN), which has been widely implemented across over 90% of the "Fortune" 500…
Soft Systems Methodology for Personalized Learning Environment
ERIC Educational Resources Information Center
Nair, Uday
2015-01-01
There are two sides to a coin when it comes to implementing technology at universities; on one side, there is the university using technologies via the virtual learning environment that seems to be outdated with the digital needs of the students, and on the other side, while implementing technology at the university learning environment the focus…
ERIC Educational Resources Information Center
Laferrière, T.; Hamel, C.; Searson, M.
2013-01-01
Representing issues discussed at the EduSummIT 2011 relative to essential conditions and barriers to successful technology integration, this article presents a systemic analysis of barriers that needed to be overcome for an information technology initiative (Remote Networked School project) to be successfully implemented. The analysis was…
ERIC Educational Resources Information Center
Webb, Angela W.; Bunch, J. C.; Wallace, Maria F.
2015-01-01
In today's technological age, visions for technology integration in the classroom continue to be explored and examined. Digital game-based learning is one way to purposefully integrate technology while maintaining a focus on learning objectives. This case study sought to understand agriscience teachers' experiences implementing digital game-based…
Learning about Urban Ecology through the Use of Visualization and Geospatial Technologies
ERIC Educational Resources Information Center
Barnett, Michael; Houle, Meredith; Mark, Sheron; Strauss, Eric; Hoffman, Emily
2010-01-01
During the past three years we have been designing and implementing a technology enhanced urban ecology program using geographic information systems (GIS) coupled with technology. Our initial work focused on professional development for in-service teachers and implementation in K-12 classrooms. However, upon reflection and analysis of the…
Preparing for High Technology: 30 Steps to Implementation. Research & Development Series No. 232.
ERIC Educational Resources Information Center
Abram, Robert; And Others
This planning guide is one of three that addresses the concerns of postsecondary college administrators and planners regarding the planning and implementation of technician training programs in high technology areas. It specifically focuses on a 30-step planning process that is generalizable to various high technology areas. (The other two…
ERIC Educational Resources Information Center
Office of Science and Technology Policy, Washington, DC. National Science and Technology Council.
This document is the implementation plan for the Information Technology for the 21st Century (IT[squared]) initiative. With this initiative, the Federal Government is making an important re-commitment to fundamental research in information technology. The initiative proposes $366 million in increased investments in computing, information, and…
ERIC Educational Resources Information Center
Finger, Glenn; Houguet, Belinda
2009-01-01
This study, embedded within the "Researching School Change in Technology Education" (RSCTE) project in Queensland, Australia, aimed to gain insights into the intrinsic and extrinsic challenges experienced by teachers during the implementation of technology education within primary school settings. The official publication and launch of…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-05
... Pollution Affecting Visibility and Best Available Retrofit Technology Determination AGENCY: Environmental... technology (BART) for NO X for this source. This action is being taken under section 110 and part C of the.... Visibility Protection 3. Best Available Retrofit Technology 4. The Western Regional Air Partnership and...
ERIC Educational Resources Information Center
Lee, Chia-Jung; Kim, ChanMin
2014-01-01
This study presents a refined technological pedagogical content knowledge (also known as TPACK) based instructional design model, which was revised using findings from the implementation study of a prior model. The refined model was applied in a technology integration course with 38 preservice teachers. A case study approach was used in this…
Based on the development status of British BIM, exploring China’s BIM road
NASA Astrophysics Data System (ADS)
Tiangang, Chu; hui, Li; shanjun, Zhang; Ningshan, Jiang; Dan, Zhang; Yu, Zhang; Guibo, Bao
2018-05-01
This article mainly analyses the development and application status and development trend of BIM technology after the implementation of the British government, to explore the policies and methods that our government should carry out in the development of BIM. The article also summarizes and analyses the relevant policies and standards implemented by various provincial and municipal governments in promoting BIM technology in China and summarizes the strengths and weaknesses of each other by comparing the development status of the implementation of BIM policies in various provinces and cities. The article also analysed the obstacles encountered in the implementation of some specific projects at the current stage of BIM technology, and summarized the feasible solutions. The article mainly analyses the application prospects of BIM from the technical aspects of design, the application of technology in the construction process, and the strategic implementation and operation of the company, and provides a reference for promoting the application of BIM in the construction industry in China, especially in the western region.
NASA Astrophysics Data System (ADS)
Webb, Angela W.; Bunch, J. C.; Wallace, Maria F. G.
2015-12-01
In today's technological age, visions for technology integration in the classroom continue to be explored and examined. Digital game-based learning is one way to purposefully integrate technology while maintaining a focus on learning objectives. This case study sought to understand agriscience teachers' experiences implementing digital game-based learning in an introductory animal science course. From interviews with agriscience teachers on their experiences with the game, three themes emerged: (1) the constraints of inadequate and inappropriate technologies, and time to game implementation; (2) the shift in teacher and student roles necessitated by implementing the game; and (3) the inherent competitive nature of learning through the game. Based on these findings, we recommend that pre-service and in-service professional development opportunities be developed for teachers to learn how to implement digital game-based learning effectively. Additionally, with the potential for simulations that address cross-cutting concepts in the next generation science standards, digital game-based learning should be explored in various science teaching and learning contexts.
Implementing Cleaner Printed Wiring Board Technologies: Surface Finishes
This document describes the problems, solutions, and time and effort involved in implementing alternative surface finish technologies, and this guide is produced as part of the DfE Printed Wiring Board Project
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-04
...; Federal Implementation Plan for Best Available Retrofit Technology Determination; Extension of Public... Best Available Retrofit Technology (BART) requirements for sulfur dioxide (SO 2 ) at one source in...
The flight telerobotic servicer: From functional architecture to computer architecture
NASA Technical Reports Server (NTRS)
Lumia, Ronald; Fiala, John
1989-01-01
After a brief tutorial on the NASA/National Bureau of Standards Standard Reference Model for Telerobot Control System Architecture (NASREM) functional architecture, the approach to its implementation is shown. First, interfaces must be defined which are capable of supporting the known algorithms. This is illustrated by considering the interfaces required for the SERVO level of the NASREM functional architecture. After interface definition, the specific computer architecture for the implementation must be determined. This choice is obviously technology dependent. An example illustrating one possible mapping of the NASREM functional architecture to a particular set of computers which implements it is shown. The result of choosing the NASREM functional architecture is that it provides a technology independent paradigm which can be mapped into a technology dependent implementation capable of evolving with technology in the laboratory and in space.
Bhupendra, Kumar Verma; Sangle, Shirish
2015-05-15
Firms that are dynamic and prepared to implement environmental strategies have a potential competitive advantage over their industry counterparts. Therefore, it is important to understand, what capabilities are required to implement proactive environmental strategies. The paper discusses the attributes of innovative capability required by firms in order to adopt pollution prevention and cleaner technology strategies. Empirical results show that process and behavioral innovativeness are required by firms to implement a pollution prevention strategy. In addition to process and behavioral innovativeness, firms need a top management with high risk-taking ability as well as market, product, and strategic innovativeness to implement a cleaner technology strategy. The paper proposes some important managerial implications on the basis of the above research findings. Copyright © 2015 Elsevier Ltd. All rights reserved.
Discovery of Implementation Factors That Lead to Technology Adoption in Long-Term Care.
Schoville, Rhonda R
2017-10-01
The current exploratory, qualitative study discovered and clarified implementation factors that led to technology adoption in long-term care (LTC). The Integrated Technology Implementation model guided the study of an electronic health record used in three LTC settings. Thirty key stakeholders (i.e., directors of nursing, nurses, and certified nurse aides) participated in focus groups or interviews. Findings indicated experiences were more similar than different among groups and facilities. Five major implementation themes supported by a variety of minor themes were identified. Implications for nursing include that leaders must be knowledgeable and committed to the change and engage staff throughout the implementation process. In addition, various communication and education strategies are required. [Journal of Gerontological Nursing, 43(10), 21-26.]. Copyright 2017, SLACK Incorporated.
2013-01-01
Background Healthcare technology and quality improvement programs have been identified as a means to influence healthcare costs and healthcare quality in Canada. This study seeks to identify whether the ability to implement healthcare technology by a hospital was related to usage of quality improvement programs within the hospital and whether the culture within a hospital plays a role in the adoption of quality improvement programs. Methods A cross-sectional study of Canadian hospitals was conducted in 2010. The sample consisted of hospital administrators that were selected by provincial review boards. The questionnaire consisted of 3 sections: 20 healthcare technology items, 16 quality improvement program items and 63 culture items. Results Rasch model analysis revealed that a hierarchy existed among the healthcare technologies based upon the difficulty of implementation. The results also showed a significant relationship existed between the ability to implement healthcare technologies and the number of quality improvement programs adopted. In addition, culture within a hospital served a mediating role in quality improvement programs adoption. Conclusions Healthcare technologies each have different levels of difficulty. As a consequence, hospitals need to understand their current level of capability before selecting a particular technology in order to assess the level of resources needed. Further the usage of quality improvement programs is related to the ability to implement technology and the culture within a hospital. PMID:24119419
From Research to Flight: Thinking About Implementation While Performing Fundamental Research
NASA Technical Reports Server (NTRS)
Johnson, Les
2010-01-01
This slide presentation calls for a strategy to implement new technologies. Such a strategy would allow advanced space transportation technologies to mature for exploration beyond Earth orbit. It discusses the difference between technology push versus technology pull. It also reviews the three basic technology readiness levels (TRL). The presentation traces examples of technology development to flight application: the Space Shuttle Main Engine Advanced Health Management System, the Friction Stir Welding technology the (auto-adjustable pin tool). A couple of technologies currently not in flight, but are being reviewed for potential use are: cryogenic fluid management (CFM), and solar sail propulsion. There is also an attempt to explain why new technologies are so difficult to field.
ERIC Educational Resources Information Center
Leary, Heather; Severance, Samuel; Penuel, William R.; Quigley, David; Sumner, Tamara; Devaul, Holly
2016-01-01
This paper examines the impacts of technology (e.g., Chromebooks, Google Drive) on teacher learning and student activity in the development and implementation of a deeply digital high school biology unit. Using design-based implementation research, teachers co-designed with researchers and curriculum specialists a student-centered unit aligned to…
ERIC Educational Resources Information Center
Smith, Douglas A.; Coleman, Dawn
2018-01-01
This intrinsic case study explored organizational readiness to implement a campus-wide technology initiative. Specifically, this research examined a rural community college's implementation of an "iPad campus" initiative in which all students, faculty, and staff were required to adopt iPad technology. We apply a heuristic for…
ERIC Educational Resources Information Center
Tsai, Shu-Chiao
2015-01-01
The study reports on implementing self-developed English for specific purposes (ESP) courseware for technology industries in an elective course, "English reading for technology," offered to junior students of English as a foreign language in a technical university in southern Taiwan. Courseware implementation was combined with a…
ERIC Educational Resources Information Center
Ramachandran, N.; Sivaprakasam, P.; Thangamani, G.; Anand, G.
2014-01-01
Purpose: Cloud Computing (CC) technology is getting implemented rapidly in the educational sector to improve learning, research and other administrative process. As evident from the literature review, most of these implementations are happening in the western countries such as USA, UK, while the level of implementation of CC in developing…
ERIC Educational Resources Information Center
Ghaemi, Hamed
2011-01-01
This study investigates the level of implementation of web-based instructional technology (WBIT) by the in-teaching faculties of English Language departments as factor related to faculty perception of institutional mechanisms and its partial significance as condition supporting the implementation of e-learning in university education. Using a…
Hall, Alex; Wilson, Christine Brown; Stanmore, Emma; Todd, Chris
2017-07-01
Ageing societies and a rising prevalence of dementia are associated with increasing demand for care home places. Monitoring technologies (e.g. bed-monitoring systems; wearable location-tracking devices) are appealing to care homes as they may enhance safety, increase resident freedom, and reduce staff burden. However, there are ethical concerns about the use of such technologies, and it is unclear how they might be implemented to deliver their full range of potential benefits. This study explored facilitators and barriers to the implementation of monitoring technologies in care homes. Embedded multiple-case study with qualitative methods. Three dementia-specialist care homes in North-West England. Purposive sample of 24 staff (including registered nurses, clinical specialists, senior managers and care workers), 9 relatives and 9 residents. 36 semi-structured interviews with staff, relatives and residents; 175h of observation; resident care record review. Data collection informed by Normalization Process Theory, which seeks to account for how novel interventions become routine practice. Data analysed using Framework Analysis. Findings are presented under three main themes: 1. Reasons for using technologies: The primary reason for using monitoring technologies was to enhance safety. This often seemed to override consideration of other potential benefits (e.g. increased resident freedom) or ethical concerns (e.g. resident privacy); 2. Ways in which technologies were implemented: Some staff, relatives and residents were not involved in discussions and decision-making, which seemed to limit understandings of the potential benefits and challenges from the technologies. Involvement of residents appeared particularly challenging. Staff highlighted the importance of training, but staff training appeared mainly informal which did not seem sufficient to ensure that staff fully understood the technologies; 3. Use of technologies in practice: Technologies generated frequent alarms that placed a burden upon staff, but staff were able to use their contextual knowledge to help to counter some of this burden. Some technologies offered a range of data-gathering capabilities, but were not always perceived as useful complements to practice. Implementation of monitoring technologies may be facilitated by the extent to which the technologies are perceived to enhance safety. Implementation may be further facilitated through greater involvement of all stakeholders in discussions and decision-making in order to deepen understandings about the range of potential benefits and challenges from the use of monitoring technologies. Staff training might need to move beyond functional instruction to include deeper exploration of anticipated benefits and the underlying rationale for using monitoring technologies. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
NASA Technical Reports Server (NTRS)
Loomis, Audrey; Kellner, Albrecht
1988-01-01
The Columbus Project is the European Space Agency's contribution to the International Space Station program. Columbus is planned to consist of three elements (a laboratory module attached to the Space Station base, a man-tended freeflyer orbiting with the Space Station base, and a platform in polar orbit). System definition and requirements analysis for Columbus are underway, scheduled for completion in mid-1990. An overview of the Columbus mission planning environment and operations concept as currently defined is given, and some of the challenges presented to software maintainers and ground segment personnel during mission operators are identified. The use of advanced technologies in system implementation is being explored. Both advantages of such solutions and potential problems they present are discussed, and the next steps to be taken by Columbus before targeting any functions for advanced technology implementation are summarized. Several functions in the mission planning process were identified as candidates for advanced technology implementation. These range from expert interaction with Columbus' data bases through activity scheduling and near-real-time response to departures from the planned timeline. Each function is described, and its potential for advanced technology implementation briefly assessed.
Successful Implementation of Clinical Information Technology: Seven Key Lessons from CPOE.
Gellert, G A; Hill, V; Bruner, K; Maciaz, G; Saucedo, L; Catzoela, L; Ramirez, R; Jacobs, W J; Nguyen, P; Patel, L; Webster, S L
2015-01-01
To identify and describe the most critical strategic and operational contributors to the successful implementation of clinical information technologies, as deployed within a moderate sized system of U.S. community hospitals. CHRISTUS Health is a multi-state system comprised of more than 350 services and 60 hospitals with over 9 000 physicians. The Santa Rosa region of CHRISTUS Health, located in greater San Antonio, Texas is comprised of three adult community hospital facilities and one Children's hospital each with bed capacities of 142-180. Computerized Patient Order Entry (CPOE) was first implemented in 2012 within a complex market environment. The Santa Rosa region has 2 417 credentialed physicians and 263 mid-level allied health professionals. This report focuses on the seven most valuable strategies deployed by the Health Informatics team in a large four hospital CHRISTUS region to achieve strong CPOE adoption and critical success lessons learned. The findings are placed within the context of the literature describing best practices in health information technology implementation. While the elements described involved discrete de novo process generation to support implementation and operations, collectively they represent the creation of a new customer-centric service culture in our Health Informatics team, which has served as a foundation for ensuring strong clinical information technology adoption beyond CPOE. The seven success factors described are not limited in their value to and impact on CPOE adoption, but generalize to - and can advance success in - varied other clinical information technology implementations across diverse hospitals. A number of these factors are supported by reports in the literature of other institutions' successful implementations of CPOE and other clinical information technologies, and while not prescriptive to other settings, may be adapted to yield value elsewhere.
NASA Astrophysics Data System (ADS)
Rubino-Hare, L.; Bloom, N.; Claesgens, J.; Fredrickson, K.; Henderson-Dahms, C.; Sample, J. C.
2012-12-01
From 2009-2011, with support from the National Science Foundation (ITEST, DRL-0929846) and Science Foundation Arizona (MSAG-0412-09), educators, geologists and geographers at Northern Arizona University (NAU) partnered to offer professional development for interdisciplinary teams of secondary and middle school teachers with a focus on project-based instruction (PBI) using geospatial technologies (GST). While participating in professional development teachers received support and were held accountable to NAU staff. They implemented activities and pedagogical strategies presented, increased knowledge, skills, and confidence teaching with project-based instruction integrating GST, and their students demonstrated learning gains. Changes in student understanding are only observed when teachers continue to implement change, so the question remained: did these changes in practice sustain after official project support ended? In order to determine what, if anything, teachers sustained from the professional development and the factors that promoted or hindered sustained use of teaching with GST and PBI, data were collected one to two years following the professional development. Research questions included a) what pedagogical practices did teachers sustain following the professional learning experiences? and b) what contexts were present in schools that supported or limited the use of geospatial technologies as a teaching and learning tool? Findings from this study indicate that teachers fall into three categories of sustaining implementation - reformed implementers, mechanical implementers and non-implementers. School context was less of a factor in level of implementation than teachers' beliefs and philosophy of teaching and teachers' understanding of technology integration (teaching with technology vs. teaching technology). Case studies of teacher experiences will be presented along with implications for future professional development.
Beglaryan, Mher; Petrosyan, Varduhi; Bunker, Edward
2017-06-01
In health care, information technologies (IT) hold a promise to harness an ever-increasing flow of health related information and bring significant benefits including improved quality of care, efficiency, and cost containment. One of the main tools for collecting and utilizing health data is the Electronic Health Record (EHR). EHRs implementation can face numerous barriers to acceptance including attitudes and perceptions of potential users, required effort attributed to their implementation and usage, and resistance to change. Various theories explicate different aspects of technology deployment, implementation, and acceptance. One of the common theories is the Technology Acceptance Model (TAM), which helps to study the implementation of different healthcare IT applications. The objectives of this study are: to understand the barriers of EHR implementation from the perspective of physicians; to identify major determinants of physicians' acceptance of technology; and develop a model that explains better how EHRs (and technologies in general) are accepted by physicians. The proposed model derives from a cross-sectional survey of physicians selected through multi-stage cluster sampling from the hospitals of Yerevan, Armenia. The study team designed the survey instrument based on a literature review on barriers of EHR implementation. The analysis employed exploratory structural equation modeling (ESEM) with a robust weighted least squares (WLSMV) estimator for categorical indicators. The analysis progressed in two steps: appraisal of the measurement model and testing of the structural model. The derived model identifies the following factors as direct determinants of behavioral intention to use a novel technology: projected collective usefulness; personal innovativeness; patient influence; and resistance to change. Other factors (e.g., organizational change, professional relationships, administrative monitoring, organizational support and computer anxiety) exert their effects through projected collective usefulness, perceived usefulness, and perceived ease of use. The model reconciles individual-oriented and environment-oriented theoretical approaches and proposes a Tripolar Model of Technology Acceptance (TMTA), bringing together three key pillars of the healthcare: patients, practitioners, and provider organizations. The proposed TMTA explains 85% of variance of behavioral intention to use technology. The current study draws from the barriers of EHR implementation and identifies major determinants of technology acceptance among physicians. The study proposes TMTA as affording stronger explanative and predictive abilities for the health care system. TMTA paves a long overlooked gap in TAM and its descendants, which, in organizational settings, might distort construal of technology acceptance. It also explicates with greater depth the interdependence of different participants of the healthcare and complex interactions between healthcare and technologies. Copyright © 2017 Elsevier B.V. All rights reserved.
Frønsdal, Katrine B; Facey, Karen; Klemp, Marianne; Norderhaug, Inger Natvig; Mørland, Berit; Røttingen, John-Arne
2010-07-01
The way in which a health technology is used in any particular health system depends on the decisions and actions of a variety of stakeholders, the local culture, and context. In 2009, the HTAi Policy Forum considered how health technology assessment (HTA) could be improved to optimize the use of technologies (in terms of uptake, change in use, or disinvestment) in such complex systems. In scoping, it was agreed to focus on initiatives to implement evidence-based guidance and monitoring activities. A review identified systematic reviews of implementation initiatives and monitoring activities. A two-day deliberative workshop was held to discuss key papers, members' experiences, and collectively address key questions. This consensus paper was developed by email and finalized at a postworkshop meeting. Evidence suggests that the impact and use of HTA could be increased by ensuring timely delivery of relevant reports to clearly determined policy receptor (decision-making) points. To achieve this, the breadth of assessment, implementation initiatives such as incentives and targeted, intelligent dissemination of HTA result, needs to be considered. HTA stakeholders undertake a variety of monitoring activities, which could inform optimal use of a technology. However, the quality of these data varies and is often not submitted to an HTA. Monitoring data should be sufficiently robust so that they can be used in HTA to inform optimal use of technology. Evidence-based implementation initiatives should be developed for HTA, to better inform decision makers at all levels in a health system about the optimal use of technology.
Using and choosing digital health technologies: a communications science perspective.
Ovretveit, John; Wu, Albert; Street, Richard; Thimbleby, Harold; Thilo, Friederike; Hannawa, Annegret
2017-03-20
Purpose The purpose of this paper is to explore a non-technical overview for leaders and researchers about how to use a communications perspective to better assess, design and use digital health technologies (DHTs) to improve healthcare performance and to encourage more research into implementation and use of these technologies. Design/methodology/approach Narrative overview, showing through examples the issues and benefits of introducing DHTs for healthcare performance and the insights that communications science brings to their design and use. Findings Communications research has revealed the many ways in which people communicate in non-verbal ways, and how this can be lost or degraded in digitally mediated forms. These losses are often not recognized, can increase risks to patients and reduce staff satisfaction. Yet digital technologies also contribute to improving healthcare performance and staff morale if skillfully designed and implemented. Research limitations/implications Researchers are provided with an introduction to the limitations of the research and to how communications science can contribute to a multidisciplinary research approach to evaluating and assisting the implementation of these technologies to improve healthcare performance. Practical implications Using this overview, managers are more able to ask questions about how the new DHTs will affect healthcare and take a stronger role in implementing these technologies to improve performance. Originality/value New insights into the use and understanding of DHTs from applying the new multidiscipline of communications science. A situated communications perspective helps to assess how a new technology can complement rather than degrade professional relationships and how safer implementation and use of these technologies can be devised.
NASA Technical Reports Server (NTRS)
Hunter, Gary W.
2007-01-01
The aerospace industry requires the development of a range of chemical sensor technologies for such applications as leak detection, emission monitoring, fuel leak detection, environmental monitoring, and fire detection. A range of chemical sensors are being developed based on micromachining and microfabrication technology to fabricate microsensors with minimal size, weight, and power consumption; and the use of nanomaterials and structures to develop sensors with improved stability combined with higher sensitivity, However, individual sensors are limited in the amount of information that they can provide in environments that contain multiple chemical species. Thus, sensor arrays are being developed to address detection needs in such multi-species environments. These technologies and technical approaches have direct relevance to breath monitoring for clinical applications. This presentation gives an overview of developing cutting-edge sensor technology and possible barriers to new technology implementation. This includes lessons learned from previous microsensor development, recent work in development of a breath monitoring system, and future directions in the implementation of cutting edge sensor technology.
ERIC Educational Resources Information Center
Gunuc, Selim
2015-01-01
The purpose of this basic research is to determine the problems experienced in the Technology Mentoring Program (TMP), and the study discusses how these problems affect the process in general. The implementation was carried out with teacher educators in the education faculty. 8 doctorate students (mentors) provided technology mentoring…
ERIC Educational Resources Information Center
Chapman, William E., Jr.
2009-01-01
The reputed benefits of using technology in schools have been the topic of many research studies. When the World Wide Workshop Foundation implemented their Globaloria program The reputed benefits of using technology in schools have been the topic of many research studies. When the World Wide Workshop Foundation implemented their Globaloria program…
ERIC Educational Resources Information Center
Cayton, Charity Sue-Adams
2012-01-01
Technology use and a focus on 21st century skills, coupled with recent adoption of Common Core State Standards for Mathematics, marks a new challenge for mathematics teachers. Communication, discourse, and tools for enhancing discourse (NCTM, 1991, 2000) play an integral role in successful implementation of technology and mathematics standards.…
ERIC Educational Resources Information Center
Miller, James G.
A national program is necessary to discover and implement the best ways to utilize educational technology. Several university centers for research and development on instructional technology could provide a basis for national initiative in this field. These centers should carry out basic research on systems theory, with emphasis on such fields as…
A State of the Art Review on the Impact of Technology on Skill Demand in OECD Countries.
ERIC Educational Resources Information Center
Kim, Young-Hwa
2002-01-01
Review of research since the 1980s shows a consistent trend toward higher skill demands in Organisation for Economic Cooperation and Development countries. There is evidence both that higher skills are needed to implement technology and that implementing technology raises skill requirements. Automation is displacing low-skilled jobs and creating…
Impact of Mobile Dose-Tracking Technology on Medication Distribution at an Academic Medical Center.
Kelm, Matthew; Campbell, Udobi
2016-05-01
Medication dose-tracking technologies have the potential to improve efficiency and reduce costs associated with re-dispensing doses reported as missing. Data describing this technology and its impact on the medication use process are limited. The purpose of this study is to assess the impact of dose-tracking technology on pharmacy workload and drug expense at an academic, acute care medical center. Dose-tracking technology was implemented in June 2014. Pre-implementation data were collected from February to April 2014. Post-implementation data were collected from July to September 2014. The primary endpoint was the percent of re-dispensed oral syringe and compounded sterile product (CSP) doses within the pre- and post-implementation periods per 1,000 discharges. Secondary endpoints included pharmaceutical expense generated from re-dispensing doses, labor costs, and staff satisfaction with the medication distribution process. We observed an average 6% decrease in re-dispensing of oral syringe and CSP doses from pre- to post-implementation (15,440 vs 14,547 doses; p = .047). However, when values were adjusted per 1,000 discharges, this trend did not reach statistical significance (p = .074). Pharmaceutical expense generated from re-dispensing doses was significantly reduced from pre- to post-implementation ($834,830 vs $746,466 [savings of $88,364]; p = .047). We estimated that $2,563 worth of technician labor was avoided in re-dispensing missing doses. We also saw significant improvement in staff perception of technology assisting in reducing missing doses (p = .0003), as well as improvement in effectiveness of resolving or minimizing missing doses (p = .01). The use of mobile dose-tracking technology demonstrated meaningful reductions in both the number of doses re-dispensed and cost of pharmaceuticals dispensed.
Cresswell, Kathrin; Sheikh, Aziz
2013-05-01
Implementations of health information technologies are notoriously difficult, which is due to a range of inter-related technical, social and organizational factors that need to be considered. In the light of an apparent lack of empirically based integrated accounts surrounding these issues, this interpretative review aims to provide an overview and extract potentially generalizable findings across settings. We conducted a systematic search and critique of the empirical literature published between 1997 and 2010. In doing so, we searched a range of medical databases to identify review papers that related to the implementation and adoption of eHealth applications in organizational settings. We qualitatively synthesized this literature extracting data relating to technologies, contexts, stakeholders, and their inter-relationships. From a total body of 121 systematic reviews, we identified 13 systematic reviews encompassing organizational issues surrounding health information technology implementations. By and large, the evidence indicates that there are a range of technical, social and organizational considerations that need to be deliberated when attempting to ensure that technological innovations are useful for both individuals and organizational processes. However, these dimensions are inter-related, requiring a careful balancing act of strategic implementation decisions in order to ensure that unintended consequences resulting from technology introduction do not pose a threat to patients. Organizational issues surrounding technology implementations in healthcare settings are crucially important, but have as yet not received adequate research attention. This may in part be due to the subjective nature of factors, but also due to a lack of coordinated efforts toward more theoretically-informed work. Our findings may be used as the basis for the development of best practice guidelines in this area. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Review of automated vehicle technology : policy and implementation implications.
DOT National Transportation Integrated Search
2016-03-14
The goals of this project were to undergo a systematic review of automated vehicle technologies with a focus on policy : implications, methods of implementation, regulation by states, and developments occurring on legal fronts, ultimately creating a ...
Business models for implementing geospatial technologies in transportation decision-making
DOT National Transportation Integrated Search
2007-03-31
This report describes six State DOTs business models for implementing geospatial technologies. It provides a comparison of the organizational factors influencing how Arizona DOT, Delaware DOT, Georgia DOT, Montana DOT, North Carolina DOT, and Okla...
A Case Study of Best Practices of Implementing a One-to-One Technology Program
ERIC Educational Resources Information Center
Ackley, Stacy
2017-01-01
The purpose of this case study was to describe the experiences of rural school district leaders who implemented and have sustained a one-to-one technology program at the secondary level so to provide school districts considering one-to-one implementation knowledge of best practices. This study was a qualitative, bounded case study that used a…
Implementation and Performance of GaAs Digital Signal Processing ASICs
NASA Technical Reports Server (NTRS)
Whitaker, William D.; Buchanan, Jeffrey R.; Burke, Gary R.; Chow, Terrance W.; Graham, J. Scott; Kowalski, James E.; Lam, Barbara; Siavoshi, Fardad; Thompson, Matthew S.; Johnson, Robert A.
1993-01-01
The feasibility of performing high speed digital signal processing in GaAs gate array technology has been demonstrated with the successful implementation of a VLSI communications chip set for NASA's Deep Space Network. This paper describes the techniques developed to solve some of the technology and implementation problems associated with large scale integration of GaAs gate arrays.
Towards Implementation of Green Technology in Sabah Construction Industry
NASA Astrophysics Data System (ADS)
Azland Jainudin, Noor; Jugah, Ivy; Nasrizal Awang Ali, Awang; Tawie, Rudy
2017-12-01
The construction industry in Sabah is one of the major roles for development of social, economic infrastructures and buildings in generating wealth to the state besides the tourism sector. The increasing number of construction projects particularly in the rapid developing city of Kota Kinabalu, green technology as a whole is becoming more significant as it helps to develop effective solutions to encounter global environmental issues. The objective of the research is to identify the awareness and implementation of green technology in construction industry in Kota Kinabalu, Sabah. The methodology of the research is through distributing the questionnaire to the contractors, developers, consultants, architects and state government agencies to the area in Kota Kinabalu only. The questionnaires had been analysed to find out the mean value. 100 questionnaires distributed to the respondents but merely 85 questionnaires collected have been analysed. Based on the findings, 83.5% organisations were aware with the concept of green technology in construction project. In terms of the implementation only 64.7% had been implemented in their organizations. More than 50% from the major players such as contractors, consultants, developers, architects and state government agencies were aware based on six green technology concepts in their organizations. As a conclusion, the awareness towards green policy concept in construction industry is very satisfied. Meanwhile, in terms of implementation need to be increased the number of organizations to be involved in green technology in construction industry.
ERIC Educational Resources Information Center
Sittiwong, Tipparat; Wongnam, Thanet
2015-01-01
The objectives of this study were to: 1) study the result of implementing QSCCS with Facebook; 2) study students' opinions concerning the implementation of QSCCS with Facebook. The samples were 38 Technology and Communications undergraduates who attended Printing and Advertising Technology course in academic year of 2013. The information was…
Hartley, Lou Ann
2014-06-01
Implementing technology in the clinical setting is not a project but rather a journey in transforming care delivery. As nursing leaders in healthcare and patient care support organizations embrace technology to drive reforms in quality and efficiency, growing opportunities exist to share experiences between these industries. This department submission describes the journey to nursing shared governance from the perspective of an information technology-based company realizing the goal of supporting patient care.
Usage of information safety requirements in improving tube bending process
NASA Astrophysics Data System (ADS)
Livshitz, I. I.; Kunakov, E.; Lontsikh, P. A.
2018-05-01
This article is devoted to an improvement of the technological process's analysis with the information security requirements implementation. The aim of this research is the competition increase analysis in aircraft industry enterprises due to the information technology implementation by the example of the tube bending technological process. The article analyzes tube bending kinds and current technique. In addition, a potential risks analysis in a tube bending technological process is carried out in terms of information security.
ERIC Educational Resources Information Center
Sawetrattanasatian, Oranuch
2014-01-01
Web 2.0 technology has drawn much attention recently as a fascinating tool for Information Literacy Instruction (ILI), especially in academic libraries. This research was aimed to investigate the implementation of Web 2.0 technology for ILI in Thai university libraries, in terms of information literacy skills being taught, types of Web 2.0…
ERIC Educational Resources Information Center
El-Seoud, M. Samir Abou; El-Sofany, Hosam F.; Taj-Eddin, Islam A. T. F.; Nosseir, Ann; El-Khouly, Mahmoud M.
2013-01-01
The information technology educational programs at most universities in Egypt face many obstacles that can be overcome using technology enhanced learning. An open source Moodle eLearning platform has been implemented at many public and private universities in Egypt, as an aid to deliver e-content and to provide the institution with various…
ERIC Educational Resources Information Center
Byno, Kristin Jacobson
2014-01-01
This phenomenological case study was designed to investigate the experiences educators encounter when implementing iPad technology into middle school math classrooms at a middle school in Northeast Texas. The growing popularity of the iPad mobile device has made the technology an attractive tool that can be implemented into K-12 classrooms,…
ERIC Educational Resources Information Center
Tweed, Stephanie
2013-01-01
The purpose of this quantitative study was to identify the combination of factors that pertain to the implementation of new technologies in the classroom. Specifically, the study was an analysis of the age of the teacher, years of teaching experience, quality of professional development, and teacher self-efficacy as defined by Bandura (1997) to…
ERIC Educational Resources Information Center
Bradford, Deborah J.
2010-01-01
The purpose of the study was to understand and appreciate the methodologies and procedures used in determining the extent to which an information technology (IT) organization within the eleven member State University Systems (SUS) of Florida planned, implemented, and diffused emerging educational technologies. Key findings found how critical it…
Truck size and weight enforcement technologies : implementation plan
DOT National Transportation Integrated Search
2009-06-01
The purpose of this Implementation Plan is to recommend strategies to encourage the deployment of roadside technologies to improve truck size and weight enforcement in the United States. The plan includes strategies that State practitioners can use t...
Huser, Vojtech; Rasmussen, Luke V; Oberg, Ryan; Starren, Justin B
2011-04-10
Workflow engine technology represents a new class of software with the ability to graphically model step-based knowledge. We present application of this novel technology to the domain of clinical decision support. Successful implementation of decision support within an electronic health record (EHR) remains an unsolved research challenge. Previous research efforts were mostly based on healthcare-specific representation standards and execution engines and did not reach wide adoption. We focus on two challenges in decision support systems: the ability to test decision logic on retrospective data prior prospective deployment and the challenge of user-friendly representation of clinical logic. We present our implementation of a workflow engine technology that addresses the two above-described challenges in delivering clinical decision support. Our system is based on a cross-industry standard of XML (extensible markup language) process definition language (XPDL). The core components of the system are a workflow editor for modeling clinical scenarios and a workflow engine for execution of those scenarios. We demonstrate, with an open-source and publicly available workflow suite, that clinical decision support logic can be executed on retrospective data. The same flowchart-based representation can also function in a prospective mode where the system can be integrated with an EHR system and respond to real-time clinical events. We limit the scope of our implementation to decision support content generation (which can be EHR system vendor independent). We do not focus on supporting complex decision support content delivery mechanisms due to lack of standardization of EHR systems in this area. We present results of our evaluation of the flowchart-based graphical notation as well as architectural evaluation of our implementation using an established evaluation framework for clinical decision support architecture. We describe an implementation of a free workflow technology software suite (available at http://code.google.com/p/healthflow) and its application in the domain of clinical decision support. Our implementation seamlessly supports clinical logic testing on retrospective data and offers a user-friendly knowledge representation paradigm. With the presented software implementation, we demonstrate that workflow engine technology can provide a decision support platform which evaluates well against an established clinical decision support architecture evaluation framework. Due to cross-industry usage of workflow engine technology, we can expect significant future functionality enhancements that will further improve the technology's capacity to serve as a clinical decision support platform.
Using failure mode and effects analysis to plan implementation of smart i.v. pump technology.
Wetterneck, Tosha B; Skibinski, Kathleen A; Roberts, Tanita L; Kleppin, Susan M; Schroeder, Mark E; Enloe, Myra; Rough, Steven S; Hundt, Ann Schoofs; Carayon, Pascale
2006-08-15
Failure mode and effects analysis (FMEA) was used to evaluate a smart i.v. pump as it was implemented into a redesigned medication-use process. A multidisciplinary team conducted a FMEA to guide the implementation of a smart i.v. pump that was designed to prevent pump programming errors. The smart i.v. pump was equipped with a dose-error reduction system that included a pre-defined drug library in which dosage limits were set for each medication. Monitoring for potential failures and errors occurred for three months postimplementation of FMEA. Specific measures were used to determine the success of the actions that were implemented as a result of the FMEA. The FMEA process at the hospital identified key failure modes in the medication process with the use of the old and new pumps, and actions were taken to avoid errors and adverse events. I.V. pump software and hardware design changes were also recommended. Thirteen of the 18 failure modes reported in practice after pump implementation had been identified by the team. A beneficial outcome of FMEA was the development of a multidisciplinary team that provided the infrastructure for safe technology implementation and effective event investigation after implementation. With the continual updating of i.v. pump software and hardware after implementation, FMEA can be an important starting place for safe technology choice and implementation and can produce site experts to follow technology and process changes over time. FMEA was useful in identifying potential problems in the medication-use process with the implementation of new smart i.v. pumps. Monitoring for system failures and errors after implementation remains necessary.
Ramsey, Alex; Lord, Sarah; Torrey, John; Marsch, Lisa; Lardiere, Michael
2016-01-01
This study aimed to identify barriers to use of technology for behavioral health care from the perspective of care decision makers at community behavioral health organizations. As part of a larger survey of technology readiness, 260 care decision makers completed an open-ended question about perceived barriers to use of technology. Using the Consolidated Framework for Implementation Research (CFIR), qualitative analyses yielded barrier themes related to characteristics of technology (e.g., cost and privacy), potential end users (e.g., technology literacy and attitudes about technology), organization structure and climate (e.g., budget and infrastructure), and factors external to organizations (e.g., broadband accessibility and reimbursement policies). Number of reported barriers was higher among respondents representing agencies with lower annual budgets and smaller client bases relative to higher budget, larger clientele organizations. Individual barriers were differentially associated with budget, size of client base, and geographic location. Results are discussed in light of implementation science frameworks and proactive strategies to address perceived obstacles to adoption and use of technology-based behavioral health tools.
Ramsey, Alex; Lord, Sarah; Torrey, John; Marsch, Lisa; Lardiere, Michael
2014-01-01
This study aimed to identify barriers to use of technology for behavioral health care from the perspective of care decision-makers at community behavioral health organizations. As part of a larger survey of technology readiness, 260 care decision-makers completed an open-ended question about perceived barriers to use of technology. Using the Consolidated Framework for Implementation Research (CFIR), qualitative analyses yielded barrier themes related to characteristics of technology (e.g., cost, privacy), potential end-users (e.g., technology literacy, attitudes about technology), organization structure and climate (e.g., budget, infrastructure), and factors external to organizations (e.g., broadband accessibility, reimbursement policies). Number of reported barriers was higher among respondents representing agencies with lower annual budgets and smaller client bases relative to higher budget, larger clientele organizations. Individual barriers were differentially associated with budget, size of client base, and geographic location. Results are discussed in light of implementation science frameworks and proactive strategies to address perceived obstacles to adoption and use of technology-based behavioral health tools. PMID:25192755
Project IMPACT Pilot Report: Feasibility of Implementing a Hospital-to-Home Transition Bundle.
Mallory, Leah A; Osorio, Snezana Nena; Prato, B Stephen; DiPace, Jennifer; Schmutter, Lisa; Soung, Paula; Rogers, Amanda; Woodall, William J; Burley, Kayla; Gage, Sandra; Cooperberg, David
2017-03-01
To improve hospital to home transitions, a 4-element pediatric patient-centered transition bundle was developed, including: a transition readiness checklist; predischarge teach-back education; timely and complete written handoff to the primary care provider; and a postdischarge phone call. The objective of this study was to demonstrate the feasibility of bundle implementation and report initial outcomes at 4 pilot sites. Outcome measures included postdischarge caregiver ability to teach-back key home management information and 30-day reuse rates. A multisite, observational time series using multiple planned sequential interventions to implement bundle components with non-technology-supported and technology-supported patients. Data were collected via electronic health record reviews and during postdischarge phone calls. Statistical process control charts were used to assess outcomes. Four pilot sites implemented the bundle between January 2014 and May 2015 for 2601 patients, of whom 1394 had postdischarge telephone encounters. Improvement was noted in the implementation of all bundle elements with the transitions readiness checklist posing the greatest feasibility challenge. Phone contact connection rates were 69%. Caregiver ability to teach-back essential home management information postdischarge improved from 18% to 82%. No improvement was noted in reuse rates, which differed dramatically between technology-supported and non-technology-supported patients. A pediatric care transition bundle was successfully tested and implemented, as demonstrated by improvement in all process measures, as well as caregiver home management skills. Important considerations for successful implementation and evaluation of the discharge bundle include the role of local context, electronic health record integration, and subgroup analysis for technology-supported patients. Copyright © 2017 by the American Academy of Pediatrics.
NASA Astrophysics Data System (ADS)
Gray, Janet
Purpose. The purpose of this study was to identify new or emerging technological trends and events that are likely to occur between now and 2017 that will have an impact on the commercial aviation maintenance, repair, and overhaul (MRO) industry. Further, it was the purpose of this study to examine those technological trends and events believed to provide the greatest impact and, given the experts' analysis, identify the feasibility of implementation. Methodology. This descriptive study utilized the Delphi method with a panel of twenty-four experts comprised of practitioners, theorists, and futurists. A priority matrix was utilized to determine the impact and feasibility of trend and events. Findings. The experts identified fifty-three trends and events that will impact the commercial aviation maintenance, repair, and overhaul (MRO) industry. Analysis of the priority matrix revealed eighteen trends and events were of high priority and high feasibility. Conclusions. The responses from the expert panel were examined and the findings analyzed. The following are the conclusions constructed from the data provided by the Delphi panel of experts: (1) the need to respond to the demands of the maintenance, repair, and overhaul (MRO) industry such as down time, efficiency, cost, and environmental concerns by implementing new technology, (2) the demand to integrate and implement new technology as indicative of the priority matrix scoring high importance/high feasibility, (3) to proactively address the inadequate professional development in new technologies, and (4) the consensus reached by the panel of experts of importance and feasibility of implementation of new technologies encompass eighteen trends and events. Implications and recommendations for action. The implementation of new and emerging technological advances in the commercial aviation maintenance, repair, and overhaul (MRO) industry between now and 2017 will be dependent on the technologies' capacity to reduce downtime and increase efficiency. In order to maintain America's global leadership in aviation, integration of innovated technology is key.
ERIC Educational Resources Information Center
Francis, Njoroge Ngugi; Ngugi, Margaret; Kinzi, Joab
2017-01-01
The aim of this study was to examine the influence of selected factors on implementation of Information and Communication Technology in public secondary schools in Naivasha sub-county, Kenya. The study investigated whether the ICT infrastructural cost, schools' visions, and teachers' ICT skills hinder effective implementation of ICT policy in…
NASA Astrophysics Data System (ADS)
Beygel‧, A. G.; Kutsenko, K. V.; Lavrukhin, A. A.; Magomedbekov, E. P.; Pershukov, V. A.; Sofronov, V. L.; Tyupina, E. A.; Zhiganov, A. N.
2017-01-01
The experience of implementation of the basic educational program of magistracy on direction «Nuclear Physics and Technologies» in a network form is presented. Examples of joint implementation of the educational process with employers organizations, other universities and intranet mobility of students are given.
Wozney, Lori; Newton, Amanda S; Gehring, Nicole D; Bennett, Kathryn; Huguet, Anna; Hartling, Lisa; Dyson, Michele P; McGrath, Patrick
2017-06-02
The use of technology such as computers, tablets, and smartphones to improve access to and the delivery of mental health care (eMental Health care) is growing worldwide. However, despite the rapidly expanding evidence base demonstrating the efficacy of eMental Health care, its implementation in clinical practice and health care systems remains fragmented. To date, no peer-reviewed, key-informant studies have reported on the perspectives of decision-makers concerned with whether and how to implement eMental Health care. From September to November 2015, we conducted 31 interviews with key informants responsible for leadership, policy, research, and/ or information technology in organizations influential in the adoption of technology for eMental Health care. Deductive and inductive thematic analyses of transcripts were conducted using the Behavior Change Wheel as an organizing framework. Frequency and intensity effect sizes were calculated for emerging themes to further explore patterns within the data. Key informant responses (n = 31) representing 6 developed countries and multiple organizations showed consensus on common factors impacting implementation: individual and organizational capacities (e.g., computer literacy skills [patients and providers], knowledge gaps about cyber security, limited knowledge of available services); motivational drivers of technology-based care (e.g., extending care, data analytics); and opportunities for health systems to advance eMental Health care implementation (e.g., intersectoral research, rapid testing cycles, sustainable funding). Frequency effect sizes showed strong associations between implementation and credibility, knowledge, workflow, patient empowerment, electronic medical record (EMR) integration, sustained funding and intersectoral networks. Intensity effect sizes showed the highest concentration of statements (>10% of all comments) related to funding, credibility, knowledge gaps, and patient empowerment. This study provides previously unavailable information about key informant perspectives on eMental Health care implementation. The themes that emerged, namely the need to intensify intersectoral research, measure/monitor readiness to implement, define cost-utility benchmarks, raise awareness about available technologies, and test assumptions that 'proven' technologies will be easily integrated can inform the design and evaluation of eMental Health care implementation models.
Exploring information technology adoption by family physicians: survey instrument valuation.
Dixon, D. R.; Stewart, M.
2000-01-01
As the information needs of family physicians become more complex, there will be a greater need to successfully implement the technologies needed to manage that information. The ability to stratify primary care physicians can enable the implementation process to be more efficient. This research tested a new instrument on 101 family physicians, and was able to stratify physicians into high, intermediate, and low information technology (IT) usage groups. It is expected that this stratification would allow managers of IT implementation to target specific adoption strategies for each group. The instrument is available from ddixon@julian.uwo.ca. PMID:11079870
Hospital-based health technology assessment: developments to date.
Gagnon, Marie-Pierre
2014-09-01
Health technology assessment (HTA) uses a multidisciplinary approach to answer relevant questions regarding the safety, efficacy, effectiveness and cost-effectiveness of health technologies. There is growing interest in implementing HTA methods at the hospital level because it could facilitate decision-making regarding acquisition, implementation or discontinuation of technologies or interventions within the hospital. First, this article provides an overview of current international experiences and knowledge of hospital-based HTA. Then, it presents the different types of hospital-based HTA, providing examples of each of these models, as well as their strengths and limitations. Finally, it proposes a set of emerging issues that could help inform decision-makers who consider implementing hospital-based HTA, or other stakeholders interested in the field.
McAlearney, Ann Scheck; Sieck, Cynthia J; Hefner, Jennifer L; Huerta, Timothy R
2017-01-01
In past years, policies and regulations required hospitals to implement advanced capabilities of certified electronic health records (EHRs) in order to receive financial incentives. This has led to accelerated implementation of health information technologies (HIT) in health care settings. However, measures commonly used to evaluate the success of HIT implementation, such as HIT adoption, technology acceptance, and clinical quality, fail to account for complex sociotechnical variability across contexts and the different trajectories within organizations because of different implementation plans and timelines. We propose a new focus, HIT adaptation, to illuminate factors that facilitate or hinder the connection between use of the EHR and improved quality of care as well as to explore the trajectory of changes in the HIT implementation journey as it is impacted by frequent system upgrades and optimizations. Future research should develop instruments to evaluate the progress of HIT adaptation in both its longitudinal design and its focus on adaptation progress rather than on one cross-sectional outcome, allowing for more generalizability and knowledge transfer. PMID:28882812
NASA Astrophysics Data System (ADS)
Agboola, Julius Ibukun
2014-12-01
Sustainable use and allocation of aquatic resources including water resources require implementation of ecologically appropriate technologies, efficient and relevant to local needs. Despite the numerous international agreements and provisions on transfer of technology, this has not been successfully achieved in developing countries. While reviewing some challenges to technological innovations and developments (TID), this paper analyzes five TID strategic approaches centered on grassroots technology development and provision of localized capacity for sustainable aquatic resources management. Three case studies provide examples of successful implementation of these strategies. Success requires the provision of localized capacity to manage technology through knowledge empowerment in rural communities situated within a framework of clear national priorities for technology development.
Agboola, Julius Ibukun
2014-12-01
Sustainable use and allocation of aquatic resources including water resources require implementation of ecologically appropriate technologies, efficient and relevant to local needs. Despite the numerous international agreements and provisions on transfer of technology, this has not been successfully achieved in developing countries. While reviewing some challenges to technological innovations and developments (TID), this paper analyzes five TID strategic approaches centered on grassroots technology development and provision of localized capacity for sustainable aquatic resources management. Three case studies provide examples of successful implementation of these strategies. Success requires the provision of localized capacity to manage technology through knowledge empowerment in rural communities situated within a framework of clear national priorities for technology development.
Computer-aided documentation. Quality, productivity, coding, and enhanced reimbursement.
Foxlee, R H
1993-10-01
Physicians currently use technology, where appropriate, to improve patient care, for example, MRI and three-dimensional radiotherapy dose planning. One area that has seen limited benefit from current technology is in documenting of medical information. Review of related literature and directed interviews. Technology is available to assist in documenting the initial patient encounter. Patient care, quality of practice, and reimbursement may be improved with careful implementation. It will be worthwhile for practices to examine how to implement this technology to obtain the potential benefits.
SAW chirp filter technology for satellite on-board processing applications
NASA Astrophysics Data System (ADS)
Shaw, M. D.; Miller, N. D. J.; Malarky, A. P.; Warne, D. H.
1989-11-01
Market growth in the area of thin route satellite communications services has led to consideration of nontraditional system architectures requiring sophisticated on-board processing functions. Surface acoustic wave (SAW) technology exists today which can provide implementation of key on-board processing subsystems by using multicarrier demodulators. This paper presents a review of this signal processing technology, along with a brief review of dispersive SAW device technology as applied to the implementation of multicarrier demodulators for on-board signal processing.
Artificial Gravity for Mars Missions: The Different Design and Development Options
NASA Technical Reports Server (NTRS)
Murbach, Marcus; Arno, Roger D.
2000-01-01
One of the major impediments to human Mars missions is the development of appropriate countermeasures for long term physiological response to the micro-gravity environment. A plethora of countermeasure approaches have been advanced from strictly pharmacological measures to large diameter rotating spacecraft that would simulate a 1-g environment (the latter being the most conservative from a human health perspective). The different approaches have significantly different implications not only on the overall system design of a Mars Mission Vehicle (MMV) but on the necessary earth-orbiting platform that would be required to qualify the particular countermeasure system. it is found that these different design options can be conveniently categorized in terms of the order of magnitude of the rotation diameter required (100's, 10's, 1's, 0 meters). From this, the different mass penalties associated with each category can be generally compared. The overall objective of the countermeasure system should be to maximize crew safety and comfort, minimize exercise protocol time (i.e., the time per day that each crew member would have to participate in the exercise/countermeasure), maximize countermeasure effectiveness, and minimize the associated system mass penalty of the Mars Mission Vehicle (in terms of fraction of IMLEO - Injected Mass in Low Earth Orbit).
Fluorescent Lamp Replacement Study
2017-07-01
friendly products, advances in efficiency, and lower production costs for lamps. The conversion of fluorescent bulbs to LED technology has many benefits ...of 4727 W. An economic analysis was calculated to compare the various lighting technologies that were implemented at ATC and the cost benefits ...the various lighting technologies that were implemented at ATC and the cost benefits of each, a lifecycle comparison was made between the fluorescent
2012-07-01
technologies with significant capital costs, secondary waste streams, the involvement of hazardous materials, and the potential for additional worker...or environmental exposure. A more ideal technology would involve lower capital costs, would not generate secondary waste streams, would be...of bioaugmentation technology in general include low risk to human health and the environment during implementation, low secondary waste generation
The Effects Of Disruptive Technology On Project Interdiction
2016-12-01
state of the art in personal privacy and anonymity is changing every day [11], [12]. 6 Disruptive technologies like cryptology and the blockchain ...only parties to be threatened by implementations of blockchain technology. Brooklyn-based software developer ConsenSys aims to provide the same...services as Google, utilizing a distributed network of computers that synchronizes information exchange via a blockchain implementation known as Ethereum
The iTEaCH Implementation Model: Adopting a Best-Fit Approach to Implementing ICT in Schools
ERIC Educational Resources Information Center
Choy, Michael
2013-01-01
Schools have seen an exponential increase in the range of information communication technology (ICT) being utilised for learning and teaching over the past decade, especially with the advent of the internet. What is exciting is not just more technology, but that there are more types of technology which teachers can pick and choose from, based on…
Using a sociotechnical framework to understand adaptations in health IT implementation
Novak, Laurie Lovett; Holden, Richard J; Anders, Shilo H; Hong, Jennifer Y; Karsh, Ben-Tzion
2013-01-01
Purpose When barcode medication administration (BCMA) is implemented nurses are required to integrate not only a new set of procedures or artifacts into everyday work, but also an orientation to medication safety itself that is sometimes at odds with their own. This paper describes how the nurses’ orientation (the Practice Frame) can collide with the orientation that is represented by the technology and its implementation (the System Frame), resulting in adaptations at the individual and organization levels. Methods The paper draws on two qualitative research studies that examined the implementation of BCMA in inpatient settings using observation and ethnographic fieldwork, content analysis of email communications, and interviews with healthcare professionals. Results Two frames of reference are described: the System Frame and the Practice Frame. We found collisions of these frames that prompted adaptations at the individual and organization levels. The System Frame was less integrated and flexible than the Practice Frame, less able to account for all of the dimensions of everyday patient care to which medication administration is tied. Conclusion Collisions in frames during implementation of new technology result in adaptations at the individual and organization level that can have a variety of effects. We found adaptations to be a means of evolving both the work routines and the technology. Understanding the frames of clinical workers when new technology is being designed and implemented can inform changes to technology or organizational structure and policy that can preclude unproductive or unsafe adaptations. PMID:23562140
INTERACTIVE ABANDONED MINE LANDS WORKSHOP SERIES - ACID MINE WATER TREATMENT TECHNOLOGIES
The purpose of this interactive workshop is to present and discuss active and passive acid mine wastes cleanup technologies and to discuss the apparent disconnect between their development and their implementation. The workshop addressed five main barriers to implementing innovat...
Aviation Maintenance Technology. General. Curriculum Implementation Guide.
ERIC Educational Resources Information Center
Moore, John, Jr.; And Others
This curriculum implementation guide is a scope and sequence for the general section of a course in aviation maintenance technology. The course materials were prepared through a cooperative effort of airframe and powerplant mechanics, general aviation industry representatives, Federal Aviation Administration representatives, and vocational…
Technologies for space station autonomy
NASA Technical Reports Server (NTRS)
Staehle, R. L.
1984-01-01
This report presents an informal survey of experts in the field of spacecraft automation, with recommendations for which technologies should be given the greatest development attention for implementation on the initial 1990's NASA Space Station. The recommendations implemented an autonomy philosophy that was developed by the Concept Development Group's Autonomy Working Group during 1983. They were based on assessments of the technologies' likely maturity by 1987, and of their impact on recurring costs, non-recurring costs, and productivity. The three technology areas recommended for programmatic emphasis were: (1) artificial intelligence expert (knowledge based) systems and processors; (2) fault tolerant computing; and (3) high order (procedure oriented) computer languages. This report also describes other elements required for Station autonomy, including technologies for later implementation, system evolvability, and management attitudes and goals. The cost impact of various technologies is treated qualitatively, and some cases in which both the recurring and nonrecurring costs might be reduced while the crew productivity is increased, are also considered. Strong programmatic emphasis on life cycle cost and productivity is recommended.
Implementing recovery: an analysis of the key technologies in Scotland
2011-01-01
Background Over the past ten years the promotion of recovery has become a stated aim of mental health policies within a number of English speaking countries, including Scotland. Implementation of a recovery approach involves a significant reorientation of mental health services and practices, which often poses significant challenges for reformers. This article examines how four key technologies of recovery have assisted in the move towards the creation of a recovery-oriented mental health system in Scotland. Methods Drawing on documentary analysis and a series of interviews we examine the construction and implementation of four key recovery 'technologies' as they have been put to use in Scotland: recovery narratives, the Scottish Recovery Indicator (SRI), Wellness Recovery Action Planning (WRAP) and peer support. Results Our findings illuminate how each of these technologies works to instantiate, exemplify and disseminate a 'recovery orientation' at different sites within the mental health system in order to bring about a 'recovery oriented' mental health system. They also enable us to identify some of the factors that facilitate or hinder the effectiveness of those technologies in bringing about a change in how mental health services are delivered in Scotland. These finding provide a basis for some general reflections on the utility of 'recovery technologies' to implement a shift towards recovery in mental health services in Scotland and elsewhere. Conclusions Our analysis of this process within the Scottish context will be valuable for policy makers and service coordinators wishing to implement recovery values within their own national mental health systems. PMID:21569633
Comparing video and avatar technology for a health education application for deaf people.
Chiriac, Ionuţ Adrian; Stoicu-Tivadar, Lăcrămioara; Podoleanu, Elena
2015-01-01
The article describes the steps and results of a parallel research investigating e-health systems design and implementation for deaf people both in avatar and video technology. The application translates medical knowledge and concepts in deaf sign language for impaired users through an avatar. Two types of avatar technologies are taken into consideration: Video Avatar with recorded humans interface and Animated Avatar with animated figure interface. The comparative study investigates the data collection, design, implementation and the impact study. The comparative analysis of video and animated technology for data collection shows that the video format editing requires fewer skills and results are obtained easier, quicker and less expensive. The video technology supports an easier to design and implement architecture. The impact study for 2 deaf students communities is under development and for the time being the video avatar is better perceived.
IMPLEMENTATION OF HEALTH TECHNOLOGY ASSESSMENT WORK IN A HOSPITAL IN KAZAKHSTAN.
Kosherbayeva, Lyazzat; Hailey, David; Kurakbaev, Kural; Tsoy, Aleksey; Zhuzzhanov, Ormanbek; Donbay, Abilay; Kumar, Ainur; Nadyrov, Kamalzhan
2016-01-01
The aim of this study was to implement health technology assessment (HA) in the First General City Hospital in Astana, Kazakhstan. We organized trainings to familiarize hospital staff with the purpose and details of HTA. An HTA committee was established, with representation from hospital physicians and managers, and criteria for prioritization of health technologies determined. Clinical departments of the hospital were asked to prepare applications for new technologies for their services. The HTA committee reviewed five applications and selected a technology from one of these, on single incision laparoscopic surgery (SILS), for assessment. A short HTA report on SILS was prepared, covering its safety, clinical effectiveness, and cost effectiveness. The report was used to support a request to the Department of Health for additional funding to implement this technology within the hospital. This funding was approved and SILS was established in several hospital departments. This successful initial experience with HTA has paved the way for its routine use by the hospital for informing decisions on the procurement and use of new health technologies.
Beebe, Catherine R R; Gurenlian, JoAnn R; Rogo, Ellen J
2014-06-01
A growing body of literature suggests that today's learners have changed and education must change as well since Millennial generation students expect technology to be used in their coursework. This study sought to determine what educational technology is being used in U.S. dental hygiene programs, what student and faculty perceptions are of the effectiveness of technology, and what barriers exist to implementing educational technology. A stratified random sample of 120 entry-level dental hygiene programs nationwide were invited to participate in a survey. Fourteen programs participated, yielding a pool of 415 potential individual participants; out of those, eighty-four student and thirty-eight faculty respondents were included in the analysis, a total of 122. Results were analyzed using descriptive statistics and a Mann-Whitney U test (p<0.05). Faculty and student respondents agreed on the effectiveness of educational technology in all areas except clickers and wikis. The faculty members tended to rate the effectiveness of educational technology higher than did the students. The greatest perceived barrier to implementing technology was technical difficulties. This study suggests that support services should be available to faculty and students to ensure successful implementation of technology. Dental hygiene educators have adopted many types of educational technology, but more data are needed to determine best practices.
SITE TECHNOLOGY CAPSULE: TERRA-KLEEN SOLVENT EXTRACTION TECHNOLOGY
Remediation of PCBs in soils has been difficult to implement on a full-scale, cost-effective basis. The Terra-Kleen solvent extraction system has overcome many of the soil handling, contaminant removal, and regulatory restrictions that have made it difficult to implement a cost-e...
Developing Intranets: Practical Issues for Implementation and Design.
ERIC Educational Resources Information Center
Trowbridge, Dave
1996-01-01
An intranet is a system which has "domesticated" the technologies of the Internet for specific organizational settings and goals. Although the adaptability of Hypertext Markup Language to intranets is sometimes limited, implementing various protocols and technologies enable organizations to share files among heterogeneous computers,…
Karlsson, P; Johnston, C; Barker, K
2017-07-01
With family-centred care widely recognized as a cornerstone for effective assistive technology service provision, the current study was undertaken to investigate to what extent such approaches were used by schools when assistive technology assessments and implementation occurred in the classroom. In this cross-sectional study, we compare survey results from parents (n = 76), school staff (n = 33) and allied health professionals (n = 65) with experience in the use of high-tech assistive technology. Demographic characteristics and the stakeholders' perceived helpfulness and frequency attending assessment and set-up sessions were captured. To evaluate how family-centred the assistive technology services were perceived to be, the parents filled out the Measure of Processes of Care for Caregivers, and the professionals completed the Measure of Processes of Care for Service Providers. Descriptive statistics and one-way analysis of variance were used to conduct the data analysis. Findings show that parents are more involved during the assessment stage than during the implementation and that classroom teachers are often not involved in the initial stage. Speech pathologists in particular are seen to be to a great extent helpful when implementing assistive technology in the classroom. This study found that family-centred service is not yet fully achieved in schools despite being endorsed in early intervention and disability services for over 20 years. No statistically significant differences were found with respect to school staff and allied health professionals' roles, their years of experience working with students with cerebral palsy and the scales in the Measure of Processes of Care for Service Providers. To enhance the way technology is matched to the student and successfully implemented, classroom teachers need to be fully involved in the whole assistive technology process. The findings also point to the significance of parents' involvement, with the support of allied health professionals, in the process of selecting and implementing assistive technology in the classroom. © 2017 John Wiley & Sons Ltd.
The National Shipbuilding Research Program. Shipyard MACT Implementation Plan and Compliance Tools
1996-06-01
display a currently valid OMB control number. 1. REPORT DATE JUN 1996 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The National...ACHIEVABLE CONTROL TECHNOLOGY SECTION TWO: MODEL SHIPYARD IMPLEMENTATION PLAN SECTION THREE: THINNING RATION CALCULATION SHEETS FOR OPTIONS 2 & 3 AND...INTERPRETATION OF THE SHIPYARD MAXIMUM ACHIEVABLE CONTROL TECHNOLOGY EPA’s Maximum Achievable Control Technology Rule for Shipyards: A Plain English
Modeling and Simulation Roadmap to Enhance Electrical Energy Security of U.S. Naval Bases
2012-03-01
evaluating power system architectures and technologies and, therefore, can become a valuable tool for the implementation of the described plan for Navy...a well validated and consistent process for evaluating power system architectures and technologies and, therefore, can be a valuable tool for the...process for evaluating power system architectures and component technologies is needed to support the development and implementation of these new
Information Technology Implementation and Sustainment Model: Data Collection Instrument
2005-03-01
users (Wing and Bettinger , 2003). A GIS is a computerized system for spatial (geographically-referenced) data management (Davis and Schultz, 1990:3...AFIT/GEM/ENV/05M-15 Abstract The goal of this research was to develop a data collection instrument for an existing information technology...implementation and sustsinment model. In 2003, a unique system dynamics model was developed at the Air Force Institute of Technology to predict the
Linskell, Jeremy; Bouamrane, Matt-Mouley
2012-09-01
An assisted living space (ALS) is a technology-enabled environment designed to allow people with complex health or social care needs to remain, and live independently, in their own home for longer. However, many challenges remain in order to deliver usable systems acceptable to a diverse range of stakeholders, including end-users, and their families and carers, as well as health and social care services. ALSs need to support activities of daily-living while allowing end-users to maintain important social connections. They must be dynamic, flexible and adaptable living environments. In this article, we provide an overview of the technological landscape of assisted-living technology (ALT) and recent policies to promote an increased adoption of ALT in Scotland. We discuss our experiences in implementing technology-supported ALSs and emphasise key lessons. Finally, we propose an iterative and pragmatic user-centred implementation model for delivering ALSs in complex-needs scenarios. This empirical model is derived from our past ALS implementations. The proposed model allows project stakeholders to identify requirements, allocate tasks and responsibilities, and identify appropriate technological solutions for the delivery of functional ALS systems. The model is generic and makes no assumptions on needs or technology solutions, nor on the technical knowledge, skills and experience of the stakeholders involved in the ALS design process.
Cohen, Deborah
2015-10-01
Past research has shown abundant comorbidity between physical chronic health conditions and mental illness. The focal point of the conversation to reduce cost is better care coordination through the implementation of health information technology (HIT). At the policy level, the Health Information Technology for Economic and Clinical Health Act of 2009 (HITECH Act) was implemented as a way to increase the implementation of HIT. However, behavioral health providers have been largely excluded from obtaining access to the funds provided by the HITECH Act. Without further intervention, disjointed care coordination between physical and behavioral health providers will continue.
Cost-effective implementation of intelligent systems
NASA Technical Reports Server (NTRS)
Lum, Henry, Jr.; Heer, Ewald
1990-01-01
Significant advances have occurred during the last decade in knowledge-based engineering research and knowledge-based system (KBS) demonstrations and evaluations using integrated intelligent system technologies. Performance and simulation data obtained to date in real-time operational environments suggest that cost-effective utilization of intelligent system technologies can be realized. In this paper the rationale and potential benefits for typical examples of application projects that demonstrate an increase in productivity through the use of intelligent system technologies are discussed. These demonstration projects have provided an insight into additional technology needs and cultural barriers which are currently impeding the transition of the technology into operational environments. Proposed methods which addresses technology evolution and implementation are also discussed.
[The characteristics of medical technologies in emergency medical care hospital].
Murakhovskiĭ, A G; Babenko, A I; Bravve, Iu I; Tataurova, E A
2013-01-01
The article analyzes the implementation of major 12 diagnostic and 17 treatment technologies applied during medical care of patients with 12 key nosology forms of diseases in departments of the emergency medical care hospital No 2 of Omsk. It is established that key groups of technologies in the implementation of diagnostic process are the laboratory clinical diagnostic analyses and common diagnostic activities at reception into hospital and corresponding departments. The percentage of this kind of activities is about 78.3% of all diagnostic technologies. During the realization of treatment process the priority technologies are common curative and rehabilitation activities, intensive therapy activities and clinical diagnostic monitoring activities. All of them consist 80.1% of all curative technologies.
Implementing a One-to-One Technology Initiative in Higher Education
ERIC Educational Resources Information Center
Fridley, Daryl; Rogers-Adkinson, Diana
2015-01-01
This paper describes the process of conceptualizing and implementing a one-to-one technology initiative at a regional comprehensive university. Organized around the principle that sustainable change requires attention to clear, justifiable goals, attention to key decisions, the development of stakeholder investment, adequate training, building…
SOLUTIONS TO OVERCOME BARRIERS TO IMPLEMENTATION OF TREATMENT TECHNOLOGIES
To make treatment a viable option for remediation you must first identify the barriers to implementing treatment. The primary barrier is economics. Treatment options are relatively expensive and there is a lack of funds for treatment. The cost of technologies can be lowered by 1)...
Analyzing Team Based Engineering Design Process in Computer Supported Collaborative Learning
ERIC Educational Resources Information Center
Lee, Dong-Kuk; Lee, Eun-Sang
2016-01-01
The engineering design process has been largely implemented in a collaborative project format. Recently, technological advancement has helped collaborative problem solving processes such as engineering design to have efficient implementation using computers or online technology. In this study, we investigated college students' interaction and…
Empowerment among Teachers in Leadership Positions Involving ICT Implementation in Schools
ERIC Educational Resources Information Center
Avidov-Ungar, Orit
2018-01-01
The study identifies motivational characteristics of empowerment among teachers in leadership positions involving information and communications technology (ICT) implementation in schools. The participants were 24 teachers who were candidates for an Information and Communications Technology Leadership Award. Analysis of the in-depth interviews…
Strategic Planning Tools for Large-Scale Technology-Based Assessments
ERIC Educational Resources Information Center
Koomen, Marten; Zoanetti, Nathan
2018-01-01
Education systems are increasingly being called upon to implement new technology-based assessment systems that generate efficiencies, better meet changing stakeholder expectations, or fulfil new assessment purposes. These assessment systems require coordinated organisational effort to implement and can be expensive in time, skill and other…
NASA Astrophysics Data System (ADS)
Sechler, Phares Lochiel Coleman
State departments of public instruction require that teachers periodically update their licenses throughout their teaching careers. Various professional development events such as in-service workshops, university offerings, and special innovative programs provide opportunities for novice and experienced teachers to grow professionally. The "Team Science" workshop was designed from models supported by research that described guidelines for successful workshop strategies. In evaluating the workshop, the question was asked "Why did not all teachers implement the ideas from the workshop in their science classrooms?" This study investigates the possible relationship between teacher personality characteristics and implementation of technology innovations. Team Science was an extensive workshop program planned to develop science teachers' expertise in using computer and video technology to teach in physical science, chemistry, and physics classrooms in rural school in North Carolina. Upon evaluating the four-year effort, it was found that the 23 participants implemented the technological strategies at various levels. At the higher end of the range of technology use, some teachers exhibited complete integration of the computers and interfacing devices into both the laboratory work and the classroom inquiry. At the lower end of the range, some teachers used the technology very little. The resulting question emerged from the data collected: Do specific teacher personality characteristics (independent variables) correlate with the degree of implementation (dependent variable) of the innovative ideas and tools used in the teacher's science classroom after the in-service workshop? To determine if there were any significant personality traits, each teacher was given five personality tests. The tests were Hunt's Conceptual Development Test, the Paragraph Completion Test; James Rest's Defining Issues Test; Simmons Personal Survey, an emotional tendency test; the Myers-Briggs Type Indicator; and Riggs and Enochs Self-Efficacy Test. The data were analyzed using descriptive statistics, multiple regression, and factor analysis to see what variables were predictors of implementation. The regression analysis revealed that subtests from Myers-Briggs Type Indicator, Simmons Personal Survey, Hunt's Paragraph Completion Test, and Rest's Defining Issues Test could be used to predict implementation. Factor analysis indicated teachers who implemented the technology were "risk takers" and "flexible planners."
2011-01-01
Background Workflow engine technology represents a new class of software with the ability to graphically model step-based knowledge. We present application of this novel technology to the domain of clinical decision support. Successful implementation of decision support within an electronic health record (EHR) remains an unsolved research challenge. Previous research efforts were mostly based on healthcare-specific representation standards and execution engines and did not reach wide adoption. We focus on two challenges in decision support systems: the ability to test decision logic on retrospective data prior prospective deployment and the challenge of user-friendly representation of clinical logic. Results We present our implementation of a workflow engine technology that addresses the two above-described challenges in delivering clinical decision support. Our system is based on a cross-industry standard of XML (extensible markup language) process definition language (XPDL). The core components of the system are a workflow editor for modeling clinical scenarios and a workflow engine for execution of those scenarios. We demonstrate, with an open-source and publicly available workflow suite, that clinical decision support logic can be executed on retrospective data. The same flowchart-based representation can also function in a prospective mode where the system can be integrated with an EHR system and respond to real-time clinical events. We limit the scope of our implementation to decision support content generation (which can be EHR system vendor independent). We do not focus on supporting complex decision support content delivery mechanisms due to lack of standardization of EHR systems in this area. We present results of our evaluation of the flowchart-based graphical notation as well as architectural evaluation of our implementation using an established evaluation framework for clinical decision support architecture. Conclusions We describe an implementation of a free workflow technology software suite (available at http://code.google.com/p/healthflow) and its application in the domain of clinical decision support. Our implementation seamlessly supports clinical logic testing on retrospective data and offers a user-friendly knowledge representation paradigm. With the presented software implementation, we demonstrate that workflow engine technology can provide a decision support platform which evaluates well against an established clinical decision support architecture evaluation framework. Due to cross-industry usage of workflow engine technology, we can expect significant future functionality enhancements that will further improve the technology's capacity to serve as a clinical decision support platform. PMID:21477364
Adoption, reach, and implementation of a cancer education intervention in African American churches.
Santos, Sherie Lou Zara; Tagai, Erin K; Scheirer, Mary Ann; Bowie, Janice; Haider, Muhiuddin; Slade, Jimmie; Wang, Min Qi; Holt, Cheryl L
2017-03-14
Use of technology is increasing in health promotion and has continued growth potential in intervention research. Guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework, this paper reports on the adoption, reach, and implementation of Project HEAL (Health through Early Awareness and Learning)-a community-based implementation trial of a cancer educational intervention in 14 African American churches. We compare adoption, reach, and implementation at the organizational and participant level for churches in which lay peer community health advisors (CHAs) were trained using traditional classroom didactic methods compared with a new online system. Fifteen churches were randomized to one of two study groups in which two CHAs per church were trained through either classroom ("Traditional"; n = 16 CHAs in 8 churches) or web-based ("Technology"; n = 14 CHAs in 7 churches) training methods. Once trained and certified, all CHAs conducted a series of three group educational workshops in their churches on cancer early detection (breast, prostate, and colorectal). Adoption, reach, and implementation were assessed using multiple data sources including church-level data, participant engagement in the workshops, and study staff observations of CHA performance. The project had a 41% overall adoption rate at the church level. In terms of reach, a total of 375 participants enrolled in Project HEAL-226 participants in the Traditional group (43% reach) and 149 in the Technology group (21% reach; p < .10). Implementation was evaluated in terms of adherence, dosage, and quality. All churches fully completed the three workshops; however, the Traditional churches took somewhat longer (M = 84 days) to complete the workshop series than churches in the Technology group (M = 64 days). Other implementation outcomes were comparable between both the Traditional and Technology groups (p > .05). Overall, the Project HEAL intervention had reasonable adoption, though reach could have been better. Implementation was strong across both study groups, suggesting the promise of using web-based methods to disseminate and implement evidence-based interventions in faith-based settings and other areas where community health educators work to eliminate health disparities.
NASA Astrophysics Data System (ADS)
Bavdaz, Marcos; Wille, Eric; Shortt, Brian; Fransen, Sebastiaan; Collon, Maximilien; Barriere, Nicolas; Yanson, Alexei; Vacanti, Giuseppe; Haneveld, Jeroen; van Baren, Coen; Zuknik, Karl-Heinz; Christensen, Finn; Della Monica Ferreira, Desiree; Krumrey, Michael; Burwitz, Vadim; Pareschi, Giovanni; Spiga, Daniele; Valsecchi, Giuseppe; Vernani, Dervis
2016-07-01
ATHENA (Advanced Telescope for High ENergy Astrophysics) is being studied by the European Space Agency (ESA) as the second large science mission, with a launch slot in 2028. System studies and technology preparation activities are on-going. The optics of the telescope is based on the modular Silicon Pore Optics (SPO), a novel X-ray optics technology significantly benefiting from spin-in from the semiconductor industry. Several technology development activities are being implemented by ESA in collaboration with European industry and institutions. The related programmatic background, technology development approach and the associated implementation planning are presented.
An Overview of Solar Sail Propulsion within NASA
NASA Technical Reports Server (NTRS)
Johnson, Les; Swartzlander, Grover A.; Artusio-Glimpse, Alexandra
2013-01-01
Solar Sail Propulsion (SSP) is a high-priority new technology within The National Aeronautics and Space Administration (NASA), and several potential future space missions have been identified that will require SSP. Small and mid-sized technology demonstration missions using solar sails have flown or will soon fly in space. Multiple mission concept studies have been performed to determine the system level SSP requirements for their implementation and, subsequently, to drive the content of relevant technology programs. The status of SSP technology and potential future mission implementation within the United States (US) will be described.
2011-06-01
testing and evaluation of SBIR and STTR technologies in SBIR and STTR Phases II and III. The implementation requirements were specified in the text of...manufacturing technologies through the SBIR and STTR programs. Fourth, Congress clarified the authority to conduct testing and evaluation of SBIR and STTR...17 A. SURVEY GOALS ..........................................................................................17 B. SURVEY DESIGN
Design and Implementation of Campus Application APP Based on Android
NASA Astrophysics Data System (ADS)
dongxu, Zhu; yabin, liu; xian lei, PI; weixiang, Zhou; meng, Huang
2017-07-01
In this paper, "Internet + campus" as the entrance of the Android technology based on the application of campus design and implementation of Application program. Based on GIS(Geographic Information System) spatial database, GIS spatial analysis technology, Java development technology and Android development technology, this system server adopts the Model View Controller architectue to realize the efficient use of campus information and provide real-time information of all kinds of learning and life for campus student at the same time. "Fingertips on the Institute of Disaster Prevention Science and Technology" release for the campus students of all grades of life, learning, entertainment provides a convenient.
NASA Technical Reports Server (NTRS)
1988-01-01
As the NASA Center responsible for assembly, checkout, servicing, launch, recovery and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing emphasis on its research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects in this Kennedy Space Center 1988 Annual Report.
Looking Beyond the Valley: A Five-Year Case Study of Course Innovation.
ERIC Educational Resources Information Center
Allen, Gary K.; Wedman, John F.; Folk, Lillian C.
2001-01-01
Examined longitudinal changes in student course evaluations throughout the process of implementing information technology-enhanced delivery of a veterinary immunology course. Found that student ratings of almost all aspects of the course and instruction declined significantly during the five-year period of technology implementation and then…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-13
... Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available Control Technology for the... control technology (RACT) for oxides of nitrogen (NO X ) and volatile organic compounds (VOCs) for the... business information (CBI) or other information whose disclosure is restricted by statute. Certain other...
Cost-Effective and High-Resolution Subsurface Characterization Using Hydraulic Tomography
2017-08-28
implementation and compare costs associated with HT and conventional methods. TECHNOLOGY DESCRIPTION The HT concept is analogous to the Computerized...develop guidance for HT field implementation and compare costs associated with HT and conventional methods. 15. SUBJECT TERMS Subsurface...3 2.1 TECHNOLOGY DESCRIPTION
Mobile Technologies Enhance the E-Learning Opportunity
ERIC Educational Resources Information Center
Chuang, Keh-Wen
2009-01-01
The objective of this paper is to identify the mobile technologies that enhance the E-Learning opportunity, examine the educational benefits and implementation issues in mobile learning, discuss the guidelines for implementing effective mobile learning, identify the current application and operation of mobile learning, and discuss the future of…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-14
... Promulgation of Air Quality Implementation Plans; Maryland; Reasonably Available Control Technology for the 1997 8-Hour Ozone National Ambient Air Quality Standard AGENCY: Environmental Protection Agency (EPA... available control technology (RACT) for the 1997 8-hour ozone national ambient air quality standard (NAAQS...
Implementing the Big6: Context, Context, Context.
ERIC Educational Resources Information Center
Eisenberg, Mike
1998-01-01
Emphasizes the importance of context within the curriculum when implementing the Big6 information and technology skills. Curriculum mapping is described as a means of gathering and displaying information about curriculum units which can then be analyzed to select units and assignments best suited to integrated information and technology skills…
The deep space network, Volume 11
NASA Technical Reports Server (NTRS)
1972-01-01
Deep Space Network progress in flight project support, Tracking and Data Acquisition research and technology, network engineering, hardware and software implementation, and operations are presented. Material is presented in each of the following categories: description of DSN; mission support; radio science; support research and technology; network engineering and implementation; and operations and facilities.
Technology-Based Literacy Instruction for English Language Learners
ERIC Educational Resources Information Center
White, Erin L.; Gillard, Sharlett
2011-01-01
There is a growing need to implement an alternative and viable solution in U.S. K-12 schools that will address the ever-growing gap that the rapidly growing English language learner (ELL) population presents. This article examines various technology-based solutions, and their potential impact. The systematic implementation of these…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-27
... Retrofit Technology Requirements for Eastman Chemical Company AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is finalizing approval of the Best Available Retrofit Technology (BART... retrofitting its facility pursuant to the BART determination for SO 2 emissions (hereafter referred to as the...
Processes and Planning Structure Required for Implementing a Collegewide Area Network.
ERIC Educational Resources Information Center
Lapenta, Susan; Lutz, Todd
Since 1984, Arizona's Mohave Community College (MCC) has implemented innovative educational technology to better serve students, including an instructional television system to serve remote locations and a distance learning program. In 1993, the college initiated a project to upgrade its technological capabilities through the establishment of a…
Professional Development in Educational Technology through Teacher Support Teams
ERIC Educational Resources Information Center
Alvarado, Guillermo
2017-01-01
Since the turn of the 21st century, the implementation of instructional technologies in the secondary classroom has increased exponentially. As a result, teacher support in its implementation has become paramount. Using a qualitative case study design, this research explored teachers' and administrators' perceptions of teacher support teams that…
Project-Based Learning in Electronic Technology: A Case Study
ERIC Educational Resources Information Center
Li, Li
2015-01-01
A case study of project-based learning (PBL) implemented in Tianjin University of Technology and Education is presented. This multidiscipline project is innovated to meet the novel requirements of industry while keeping its traditional effectiveness in driving students to apply knowledge to practice and problem-solving. The implementation of PBL…
Crossing the Chasm with Classroom Response Systems
ERIC Educational Resources Information Center
Towns, Marcy H.
2010-01-01
Research and literature on the adoption of technology provides a useful lens through which to view the adoption and implementation of classroom response systems (CRS). The technology adoption life cycle describes groups of adopters in ways that are helpful in understanding the adoption and sustained implementation of CRS in chemistry departments.…
Implementing a Project-Based Technology Program for High School Women.
ERIC Educational Resources Information Center
Boudria, Theodore J.
2002-01-01
Describes the successful implementation of a Women in Technology (WIT) Project-Based Learning Program in High Tech Manufacturing by the Tech Prep Consortium at Bristol Community College (Massachusetts). Reports that the program's success was mainly due to the establishment of partnerships with industry, government, and education, including area…
Implementing Technology in Flowing Wells Schools: An Analysis of Leadership.
ERIC Educational Resources Information Center
Hamilton, Marc D.
This paper discusses technology implementation at Flowing Wells, a 10-school district in Tucson, Arizona. The leadership strategies employed by the assistant superintendent, coupled with the district's core values, brought together a cadre of teachers, parents, and administrators focused on assembling the foundation of the district's technology…
Collaboration process for integrated social and health care strategy implementation.
Korpela, Jukka; Elfvengren, Kalle; Kaarna, Tanja; Tepponen, Merja; Tuominen, Markku
2012-01-01
To present a collaboration process for creating a roadmap for the implementation of a strategy for integrated health and social care. The developed collaboration process includes multiple phases and uses electronic group decision support system technology (GDSS). A case study done in the South Karelia District of Social and Health Services in Finland during 2010-2011. An expert panel of 13 participants was used in the planning process of the strategy implementation. The participants were interviewed and observed during the case study. As a practical result, a roadmap for integrated health and social care strategy implementation has been developed. The strategic roadmap includes detailed plans of several projects which are needed for successful integration strategy implementation. As an academic result, a collaboration process to create such a roadmap has been developed. The collaboration process and technology seem to suit the planning process well. The participants of the meetings were satisfied with the collaboration process and the GDSS technology. The strategic roadmap was accepted by the participants, which indicates satisfaction with the developed process.
45 CFR 170.300 - Applicability.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.300...
45 CFR 170.300 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.300...
45 CFR 170.300 - Applicability.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.300...
45 CFR 170.300 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.300...
45 CFR 170.300 - Applicability.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.300...
Boonen, Marcel Jmh; Vosman, Frans Jh; Niemeijer, Alistair R
2016-06-01
Even though it is often presumed that the use of technology like medication administration technology is both safer and more effective, the importance of nurses' know-how is not to be underestimated. In this article, we accordingly try to argue that nurses' labor, including their different forms of knowledge, must play a crucial role in the development, implementation and use of medication administration technology. Using three different theoretical perspectives ('heuristic lenses') and integrating this with our own ethnographic research, we will explore how nursing practices change through the use of medication technology. Ultimately, we will argue that ignoring (institutional) complexity and the various types of important knowledge that nurses have, will seriously complicate the implementation of medication administration technology. © 2015 John Wiley & Sons Ltd.
Integrating technology into radiologic science education.
Wertz, Christopher Ira; Hobbs, Dan L; Mickelsen, Wendy
2014-01-01
To review the existing literature pertaining to the current learning technologies available in radiologic science education and how to implement those technologies. Only articles from peer-reviewed journals and scholarly reports were used in the research for this review. The material was further restricted to those articles that emphasized using new learning technologies in education, with a focus on radiologic science education. Teaching in higher education is shifting from a traditional classroom-based lecture format to one that incorporates new technologies that allow for more varied and diverse educational models. Radiologic technology educators must adapt traditional education delivery methods to incorporate current technologies. Doing so will help engage the modern student in education in ways in which they are already familiar. As students' learning methods change, so must the methods of educational delivery. The use of new technologies has profound implications for education. If implemented properly, these technologies can be effective tools to help educators.
Baseman, Janet; Revere, Debra; Painter, Ian; Stangenes, Scott; Lilly, Michelle; Beaton, Randal; Calhoun, Rebecca; Meischke, Hendrika
2018-05-04
Our public health emergency response system relies on the "first of the first responders"-the emergency call center workforce that handles the emergency needs of a public in distress. Call centers across the United States have been preparing for the "Next Generation 9-1-1" initiative, which will allow citizens to place 9-1-1 calls using a variety of digital technologies. The impacts of this initiative on a workforce that is already highly stressed is unknown. There is concern that these technology changes will increase stress, reduce job performance, contribute to maladaptive coping strategies, lower employee retention, or change morale in the workplace. Understanding these impacts to inform approaches for mitigating the health and performance risks associated with new technologies is crucial for ensuring the 911 system fulfills its mission of providing optimal emergency response to the public. Our project is an observational, prospective cohort study framed by the first new technology that will be implemented: text-to-911 calling. Emergency center call takers will be recruited nationwide. Data will be collected by online surveys distributed at each center before text-to-911 implementation; within the first month of implementation; and 6 months after implementation. Primary outcome measures are stress as measured by the Calgary Symptoms of Stress Index, use of sick leave, job performance, and job satisfaction. Primary analyses will use mixed effects regression models and mixed effects logistic regression models to estimate the change in outcome variables associated with text-to-911 implementation. Multiple secondary analyses will examine effects of stress on absenteeism; associations between technology attitudes and stress; effects of implementation on attitudes towards technology; and mitigating effects of job demands, job satisfaction, attitudes towards workplace technology and workplace support on change in stress. Our public health dependence on this workforce for our security and safety makes it imperative that the impact of technological changes such as text-to-911 are researched so appropriate intervention efforts to can be developed. Failing to protect our 9-1-1 call takers from predictable health risks would be similar to knowingly exposing field emergency responders to a toxic situation without following OSHA required training and practice standards assuring their protection.
Supporting Teachers Learning Through the Collaborative Design of Technology-Enhanced Science Lessons
NASA Astrophysics Data System (ADS)
Kafyulilo, Ayoub C.; Fisser, Petra; Voogt, Joke
2015-12-01
This study used the Interconnected Model of Professional Growth (Clarke & Hollingsworth in Teaching and Teacher Education, 18, 947-967, 2002) to unravel how science teachers' technology integration knowledge and skills developed in a professional development arrangement. The professional development arrangement used Technological Pedagogical Content Knowledge as a conceptual framework and included collaborative design of technology-enhanced science lessons, implementation of the lessons and reflection on outcomes. Support to facilitate the process was offered in the form of collaboration guidelines, online learning materials, exemplary lessons and the availability of an expert. Twenty teachers participated in the intervention. Pre- and post-intervention results showed improvements in teachers' perceived and demonstrated knowledge and skills in integrating technology in science teaching. Collaboration guidelines helped the teams to understand the design process, while exemplary materials provided a picture of the product they had to design. The availability of relevant online materials simplified the design process. The expert was important in providing technological and pedagogical support during design and implementation, and reflected with teachers on how to cope with problems met during implementation.
Tal, Orna; Lomnicky, Yosef
2012-06-01
Advanced health systems worldwide strive to adopt new technologies that will ensure improved health and better clinical outcomes. The implementation of new medical technologies is affected by medical factors as well as economic and social forces, influencing both the individual and the health care providers. Chronic disease management is a major challenge to governments, as a result of the cumulative effects of chronic morbidity, life expectancy, quality of life and the national burden of disease due to accelerating medical expenditure. Psoriasis, a common chronic disease, for which advanced technologies were recently implemented, was chosen as a case study. The distribution of utility of various technologies for the treatment of psoriasis over the past nine years was analyzed to categorize "patterns of behavior" in accordance with the lifecycle of medical technology described in the Literature. It is expected that these changing trends will produce overall economic consequences, on direct expenditure combined with a reduction in some health services. Analyzing these clinical and economic trends, may add important considerations for the adoption of emerging medical technologies, presenting an important tool for policymakers at at all levels.
Internet-based computer technology on radiotherapy.
Chow, James C L
2017-01-01
Recent rapid development of Internet-based computer technologies has made possible many novel applications in radiation dose delivery. However, translational speed of applying these new technologies in radiotherapy could hardly catch up due to the complex commissioning process and quality assurance protocol. Implementing novel Internet-based technology in radiotherapy requires corresponding design of algorithm and infrastructure of the application, set up of related clinical policies, purchase and development of software and hardware, computer programming and debugging, and national to international collaboration. Although such implementation processes are time consuming, some recent computer advancements in the radiation dose delivery are still noticeable. In this review, we will present the background and concept of some recent Internet-based computer technologies such as cloud computing, big data processing and machine learning, followed by their potential applications in radiotherapy, such as treatment planning and dose delivery. We will also discuss the current progress of these applications and their impacts on radiotherapy. We will explore and evaluate the expected benefits and challenges in implementation as well.
NIX, JACQUELINE; COMANS, TRACY
2017-01-01
This article reports upon an initiative to improve the timeliness of occupational therapy home visits for discharge planning by implementing technology solutions while maintaining patient safety. A community hospital in Queensland, Australia, hosted a process evaluation that examined which aspects of home visiting could be replaced or augmented by alternative technologies. Strategies were trialled, implemented and assessed using the number of home visits completed and the time from referral to completion as outcomes. A technology-enhanced solution called “Home Quick” was developed using technology to facilitate pre-discharge home visits. The implementation of Home Quick resulted in an increase in the number of home visits conducted prior to discharge (50% increase from 145 to 223) and significantly increased the number of patients seen earlier following referral (X2=69.3; p<0.001). The substitution of direct home visits with technology-enabled remote visits is suitable for a variety of home visiting scenarios traditionally performed by occupational therapists. PMID:28814994
Walz-Flannigan, Alisa; Kotsenas, Amy L; Hein, Shelly; Persons, Kenneth R; Langer, Steve G; Erickson, Bradley J; Tjelta, Jason A; Luetmer, Patrick H
2015-04-01
This article illustrates the importance of radiologist engagement in the successful implementation of radiology-information technology (IT) projects through the example of establishing a mobile image viewing solution for health care professionals. With an understanding of the types of decisions that benefit from radiologist input, this article outlines an overall project framework to provide a context for how radiologists might engage in the project cycle.
Computer-Managed Instruction: Theory, Application, and Some Key Implementation Issues.
1984-03-01
who have endorsed computer technology but fail to adopt it . As one educational consultant claims: "Educators appear to have a deep-set skepticism toward...widespread use. i-1 II. BACKGROUND A. HISTORICAL PERSPECTIVE In the mid-1950’s, while still in its infancy, computer technology entered the world of education...to utilize the new technology , and to do it most.. extensively. Implementation of CMI in a standalone configuration using microcomputers has been
Brown, C Hendricks; Mohr, David C; Gallo, Carlos G; Mader, Christopher; Palinkas, Lawrence; Wingood, Gina; Prado, Guillermo; Kellam, Sheppard G; Pantin, Hilda; Poduska, Jeanne; Gibbons, Robert; McManus, John; Ogihara, Mitsunori; Valente, Thomas; Wulczyn, Fred; Czaja, Sara; Sutcliffe, Geoff; Villamar, Juan; Jacobs, Christopher
2013-06-01
African Americans and Hispanics in the United States have much higher rates of HIV than non-minorities. There is now strong evidence that a range of behavioral interventions are efficacious in reducing sexual risk behavior in these populations. Although a handful of these programs are just beginning to be disseminated widely, we still have not implemented effective programs to a level that would reduce the population incidence of HIV for minorities. We proposed that innovative approaches involving computational technologies be explored for their use in both developing new interventions and in supporting wide-scale implementation of effective behavioral interventions. Mobile technologies have a place in both of these activities. First, mobile technologies can be used in sensing contexts and interacting to the unique preferences and needs of individuals at times where intervention to reduce risk would be most impactful. Second, mobile technologies can be used to improve the delivery of interventions by facilitators and their agencies. Systems science methods including social network analysis, agent-based models, computational linguistics, intelligent data analysis, and systems and software engineering all have strategic roles that can bring about advances in HIV prevention in minority communities. Using an existing mobile technology for depression and 3 effective HIV prevention programs, we illustrated how 8 areas in the intervention/implementation process can use innovative computational approaches to advance intervention adoption, fidelity, and sustainability.
NASA Astrophysics Data System (ADS)
Kumar, Sameer; Kadow, Brooke B.; Lamkin, Melissa K.
2011-05-01
As radio-frequency identification (RFID) implementation becomes more widespread it is important for managers to consider if this technology is right for their businesses. This study examines challenges of RFID implementation along with a cost-benefit analysis of a pharmaceuticals manufacturer's supply chain. Research was gathered from a variety of sources on the topic of RFID to provide an in-depth analysis of challenges and benefits found with RFID systems. Furthermore, the study reviews the real case applications of the RFID technology in healthcare and customer services. Many of the challenges with RFID stem from improper planning of the synchronisation of the supply chain and the integration of RFID technology into facilities and software systems. Customer privacy, excess information and obsolete technology are also of concern to companies considering RFID. Benefits such as increased information sharing, product visibility and real-time information help to offset these challenges. In addition, pharmaceuticals manufacturer real case application showed cost savings from reducing labour and decreased opportunities for lost product counteract the expense to implement an RFID system. This study will be of value to managers who are attempting to implement RFID technology in their companies. It is intended that readers, both academics and practitioners, will be able to identify possible challenges and mitigate them as the RFID technology is put into practice.
Djordjevic, Ivan B
2010-04-12
The Bell states preparation circuit is a basic circuit required in quantum teleportation. We describe how to implement it in all-fiber technology. The basic building blocks for its implementation are directional couplers and highly nonlinear optical fiber (HNLF). Because the quantum information processing is based on delicate superposition states, it is sensitive to quantum errors. In order to enable fault-tolerant quantum computing the use of quantum error correction is unavoidable. We show how to implement in all-fiber technology encoders and decoders for sparse-graph quantum codes, and provide an illustrative example to demonstrate this implementation. We also show that arbitrary set of universal quantum gates can be implemented based on directional couplers and HNLFs.
The Superfund Innovative Technology Evaluation Program SUMMARY AND CLOSURE REPORT
The Superfund Innovative Technology Evaluation (SITE) Program promoted the development, commercialization, and implementation of innovative hazardous waste treatment technologies for 20 years. SITE offered a mechanism for conducting joint technology demonstration and evaluation ...
Resistance to Information Technology in Public Procurement in Tanzania
ERIC Educational Resources Information Center
Nditi, Christopher
2010-01-01
Organizations have become more dependent on information technology (IT) in the 21st century. But IT implementation and use is resisted in certain sectors of Tanzania, particularly in government-run enterprises. The purpose of this study was to investigate the causes and consequences of resistance to IT development and implementation in the…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-15
... alignment of the State and Federal definition for ``major modification'' occurs as expeditiously as possible... disapproves a state rule implementing a Federal Standard. National Technology Transfer Advancement Act In..., the requirements of section 12(d) of the National Technology Transfer and Advancement Act of 1995 (15...
ERIC Educational Resources Information Center
Wills, Howard P.; Mason, Benjamin A.
2014-01-01
Technological innovations offer promise for improving intervention implementation in secondary, inclusive classrooms. A withdrawal design was employed with two high-school students in order to assess the effectiveness of a technologically delivered, self-monitoring intervention in improving on-task behavior in a science classroom. Two students…
Educational Technology, E.C.I.A. Chapter 2. Final Evaluation Report.
ERIC Educational Resources Information Center
District of Columbia Public Schools, Washington, DC. Div. of Quality Assurance.
The Planning, Monitoring and Implementing (PMI) Evaluation Model for Decision-Making was used by the District of Columbia Public Schools to monitor their Office of Educational Technology in its efforts to provide direction and coordination for computer related activities, and to plan and implement educational television projects in math and…
Working Overseas: Implementing Technology for a Branch Campus in the Middle East
ERIC Educational Resources Information Center
Chester, Timothy M.
2005-01-01
On July 5, 2003, the author landed in Qatar, a newly minted CIO from College Station, Texas. His charge is to design and implement the required IT infrastructure--including telecommunications, networking, computing, and instructional technology--necessary to support Texas A&M University's newest branch campus, Texas A&M University at Qatar…
ERIC Educational Resources Information Center
Achuonye, Keziah Akuoma
2015-01-01
This descriptive survey is hinged on predominant teaching strategies in schools, implications for curriculum implementation in Mathematics, Science and Technology. Target population consisted of teachers in primary, secondary and tertiary schools. However, purposive sample of 900 respondents was drawn from the six BRACED states namely Bayelsa,…
Developing Higher-Order Thinking Skills through WebQuests
ERIC Educational Resources Information Center
Polly, Drew; Ausband, Leigh
2009-01-01
In this study, 32 teachers participated in a year-long professional development project related to technology integration in which they designed and implemented a WebQuest. This paper describes the extent to which higher-order thinking skills (HOTS) and levels of technology implementation (LoTI) occur in the WebQuests that participants designed.…
Implementing Educational Science Television in the Third Grade Classroom
ERIC Educational Resources Information Center
Shear, Ashley
2010-01-01
When educating children, teachers need to be aware of ways to make learning engaging. For young children, with their high exposure to current technology, listening to one person all day can be boring. Children today understand technology at a faster pace than did children of previous generations, so teachers need to implement more technology…
DOE Office of Scientific and Technical Information (OSTI.GOV)
U.S. Department of Energy
2001-08-05
This case study is the latest in a series on industrial firms who are implementing energy efficient technologies and system improvements into their manufacturing processes. The case studies document the activities, savings, and lessons learned on these projects.
ERIC Educational Resources Information Center
Kallick, Bena, Ed.; Wilson, James M., III, Ed.
This book chronicles practitioners' struggles in implementing information technology, identifies the existing barriers to implementation, and provides a set of frameworks from the current understanding of this process to support learning through information creation. The chapters are: chapter 1, "A Model for Organizational Learning: The…
Data System Implementation: A Leader Navigates People Problems around Technology and Data Use
ERIC Educational Resources Information Center
Cho, Vincent; Jimerson, Jo Beth; Wayman, Jeffrey C.
2015-01-01
Computer data systems have become a lynchpin to supporting school data use. However, successfully implementing such systems is no easy task. In this case, readers explore the ways in which "technology problems" and "people problems" can be intertwined. The case follows Dr. Molly Winters as she encounters social and…
LO sources for 1-3 THz: present status and future prospective
NASA Technical Reports Server (NTRS)
Mehdi, Imran
2003-01-01
This talk will present an overview of the current technologies that are available for implementing local oscillator sources for 1-3 THz applications. Progress to date on specific components will be discussed in some detail. Outstanding issues and concerns regarding practical implementation of these new technologies will also be discussed.
ERIC Educational Resources Information Center
Sullivan, Donna Annette
2009-01-01
Many rural communities across America face several obstacles in the implementation of information and communication technologies (ICTs) initiatives and struggle with the best approaches for leveraging these elements into an economic development strategy. These obstacles include: lack of quality local ICTs infrastructure, funding, inability to…
ERIC Educational Resources Information Center
Young, Douglas; Moline, Karl; Farrell, Jill; Bierie, David
2006-01-01
Much has been written in recent years about advances in assessment technologies designed to aid decision making in the juvenile justice system. Adoption and implementation of this latest generation of actuarial tools, however, have lagged behind their development. Assessment in juvenile justice exemplifies the "science-practice gap" that…
The Feasibility of a Continuous Learning Year Program at Fashion Institute of Technology.
ERIC Educational Resources Information Center
Thomas, George Isaiah
This feasibility study provides the Fashion Institute of Technology with a number of continuous-learning-year calendar choices, along with several suggestions regarding implementation procedures. The nature of the implementation process and the issues confronting the college administrator who is willing to reschedule the college year to facilitate…
ERIC Educational Resources Information Center
Kallembach, Sheri, Comp.; And Others
This document compiles representative resources to assist state and local administrators of vocational special needs programs, special needs educators, counselors, researchers, and policymakers in implementing and complying with the Carl D. Perkins Vocational and Applied Technology Education Act of 1990. Entries in the publications section are…
RFID Technology Implementation in Two Libraries in New Delhi
ERIC Educational Resources Information Center
Madhusudhan, Margam
2010-01-01
Purpose: The purpose of this paper is to examine the use and implementation of RFID technology at the Indian Law Institute Library and National Social Science Documentation Centre Library, New Delhi. Design/methodology/approach: A survey was conducted at the two libraries, using a structured questionnaire comprising 20 questions. Findings: It was…
Fingerprints in Place of Passwords: A Study of Technology Adoption in the Nursing Profession
ERIC Educational Resources Information Center
Francisco, James R.
2010-01-01
Health care is one of the most highly regulated industries in the United States. The Health Insurance Portability and Accountability Act of 1996 (HIPAA) mandates the implementation of information systems security to protect the personal information of patients. Properly planned implementations ease the process of introducing new technologies like…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-18
... usability of government information and data for persons with disabilities. Input from private industry is sought on the following questions: What is private industry doing to implement information technology (IT...? What are state and local governments doing to implement information technology accessibility that the...
Tools and technologies for expert systems: A human factors perspective
NASA Technical Reports Server (NTRS)
Rajaram, Navaratna S.
1987-01-01
It is widely recognized that technologies based on artificial intelligence (AI), especially expert systems, can make significant contributions to the productivity and effectiveness of operations of information and knowledge intensive organizations such as NASA. At the same time, these being relatively new technologies, there is the problem of transfering technology to key personnel of such organizations. The problems of examining the potential of expert systems and of technology transfer is addressed in the context of human factors applications. One of the topics of interest was the investigation of the potential use of expert system building tools, particularly NEXPERT as a technology transfer medium. Two basic conclusions were reached in this regard. First, NEXPERT is an excellent tool for rapid prototyping of experimental expert systems, but not ideal as a delivery vehicle. Therefore, it is not a substitute for general purpose system implementation languages such a LISP or C. This assertion probably holds for nearly all such tools on the market today. Second, an effective technology transfer mechanism is to formulate and implement expert systems for problems which members of the organization in question can relate to. For this purpose, the LIghting EnGineering Expert (LIEGE) was implemented using NEXPERT as the tool for technology transfer and to illustrate the value of expert systems to the activities of the Man-System Division.
The Study on Network Examinational Database based on ASP Technology
NASA Astrophysics Data System (ADS)
Zhang, Yanfu; Han, Yuexiao; Zhou, Yanshuang
This article introduces the structure of the general test base system based on .NET technology, discussing the design of the function modules and its implementation methods. It focuses on key technology of the system, proposing utilizing the WEB online editor control to solve the input problem and regular expression to solve the problem HTML code, making use of genetic algorithm to optimize test paper and the automated tools of WORD to solve the problem of exporting papers and others. Practical effective design and implementation technology can be used as reference for the development of similar systems.
Examining the Multi-level Fit between Work and Technology in a Secure Messaging Implementation.
Ozkaynak, Mustafa; Johnson, Sharon; Shimada, Stephanie; Petrakis, Beth Ann; Tulu, Bengisu; Archambeault, Cliona; Fix, Gemmae; Schwartz, Erin; Woods, Susan
2014-01-01
Secure messaging (SM) allows patients to communicate with their providers for non-urgent health issues. Like other health information technologies, the design and implementation of SM should account for workflow to avoid suboptimal outcomes. SM may present unique workflow challenges because patients add a layer of complexity, as they are also direct users of the system. This study explores SM implementation at two Veterans Health Administration facilities. We interviewed twenty-nine members of eight primary care teams using semi-structured interviews. Questions addressed staff opinions about the integration of SM with daily practice, and team members' attitudes and experiences with SM. We describe the clinical workflow for SM, examining complexity and variability. We identified eight workflow issues directly related to efficiency and patient satisfaction, based on an exploration of the technology fit with multilevel factors. These findings inform organizational interventions that will accommodate SM implementation and lead to more patient-centered care.
NASA Technical Reports Server (NTRS)
Cole, Richard
1991-01-01
The major goals of this effort are as follows: (1) to examine technology insertion options to optimize Advanced Information Processing System (AIPS) performance in the Advanced Launch System (ALS) environment; (2) to examine the AIPS concepts to ensure that valuable new technologies are not excluded from the AIPS/ALS implementations; (3) to examine advanced microprocessors applicable to AIPS/ALS, (4) to examine radiation hardening technologies applicable to AIPS/ALS; (5) to reach conclusions on AIPS hardware building blocks implementation technologies; and (6) reach conclusions on appropriate architectural improvements. The hardware building blocks are the Fault-Tolerant Processor, the Input/Output Sequencers (IOS), and the Intercomputer Interface Sequencers (ICIS).
NASA Astrophysics Data System (ADS)
Saavedra-Duarte, L. A.; Angarita-Jerardino, A.; Ruiz, P. A.; Dulce-Moreno, H. J.; Vera-Rivera, F. H.; V-Niño, E. D.
2017-12-01
Information and Communication Technologies (ICT) are essential in the transfer of knowledge, and the Web tools, as part of ICT, are important for institutions seeking greater visibility of the products developed by their researchers. For this reason, we implemented an application that allows the information management of the FORISTOM Foundation (Foundation of Researchers in Science and Technology of Materials). The application shows a detailed description, not only of all its members also of all the scientific production that they carry out, such as technological developments, research projects, articles, presentations, among others. This application can be implemented by other entities committed to the scientific dissemination and transfer of technology and knowledge.
NASA Technical Reports Server (NTRS)
1986-01-01
As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing increasing emphasis on the Center's research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects in this Kennedy Space Center 1986 Annual Report.
Electro-Technologies. Guide to Standards and Implementation. Career & Technology Studies.
ERIC Educational Resources Information Center
Alberta Dept. of Education, Edmonton. Curriculum Standards Branch.
With this Career and Technologies Studies (CTS) curriculum guide, secondary students in Alberta can do the following: develop skills that can be applied in their daily lives; refine career-planning skills; develop technology-related skills in electro-technologies; enhance employability skills, especially in electro-technologies industries; and…
ERIC Educational Resources Information Center
Chang, I-Hua; Chin, Joseph M.; Hsu, Cheng-Mei
2008-01-01
Principals' technology leadership is strongly correlated with teachers' integration of educational technology, and technology leadership is necessary for effective utilization of technology in schooling. The article describes a study that empirically investigated teachers' perceptions of elementary schools principals' technology leadership…
A complex adaptive systems perspective of health information technology implementation.
Keshavjee, Karim; Kuziemsky, Craig; Vassanji, Karim; Ghany, Ahmad
2013-01-01
Implementing health information technology (HIT) is a challenge because of the complexity and multiple interactions that define HIT implementation. Much of the research on HIT implementation is descriptive in nature and has focused on distinct processes such as order entry or decision support. These studies fail to take into account the underlying complexity of the processes, people and settings that are typical of HIT implementations. Complex adaptive systems (CAS) is a promising field that could elucidate the complexity and non-linear interacting issues that are typical in HIT implementation. Initially we sought new models that would enable us to better understand the complex nature of HIT implementation, to proactively identify problem issues that could be a precursor to unintended consequences and to develop new models and new approaches to successful HIT implementations. Our investigation demonstrates that CAS does not provide prediction, but forces us to rethink our HIT implementation paradigms and question what we think we know. CAS provides new ways to conceptualize HIT implementation and suggests new approaches to increasing HIT implementation successes.
Lean diesel technology and human health: a case study in six Brazilian metropolitan regions.
André, Paulo Afonso de; Veras, Mariana Matera; Miraglia, Simone Georges El Khouri; Saldiva, Paulo Hilário Nascimento
2012-01-01
Due to their toxicity, diesel emissions have been submitted to progressively more restrictive regulations in developed countries. However, in Brazil, the implementation of the Cleaner Diesel Technologies policy (Euro IV standards for vehicles produced in 2009 and low-sulfur diesel with 50 ppm of sulfur) was postponed until 2012 without a comprehensive analysis of the effect of this delay on public health parameters. We aimed to evaluate the impact of the delay in implementing the Cleaner Diesel Technologies policy on health indicators and monetary health costs in Brazil. The primary estimator of exposure to air pollution was the concentration of ambient fine particulate matter (particles with aerodynamic diameters <2.5 μm, [PM2.5]). This parameter was measured daily in six Brazilian metropolitan areas during 2007-2008. We calculated 1) the projected reduction in the PM2.5 that would have been achieved if the Euro IV standards had been implemented in 2009 and 2) the expected reduction after implementation in 2012. The difference between these two time curves was transformed into health outcomes using previous dose-response curves. The economic valuation was performed based on the DALY (disability-adjusted life years) method. The delay in implementing the Cleaner Diesel Technologies policy will result in an estimated excess of 13,984 deaths up to 2040. Health expenditures are projected to be increased by nearly US$ 11.5 billion for the same period. The present results indicate that a significant health burden will occur because of the postponement in implementing the Cleaner Diesel Technologies policy. These results also reinforce the concept that health effects must be considered when revising fuel and emission policies.
Why won't they listen: Negotiating the technological and social context for science teaching
NASA Astrophysics Data System (ADS)
Liuzzo, Anna M.
The purpose of this study was to gather information to identify the obstacles and the impact an implementation of technology had in a middle school science classroom. This study explored a teaching environment where the teacher planned on using a variety of technology tools including laptops, probeware, hardware and software to promote scientific study. This study took place in two phases consisting of three consecutive years. In phase one the teacher reported great success. In phase two a shift in the school implementation created a significant impact on the learning taking place. This study identified the obstacles faced by a teacher providing an environment that combined her pedagogy with technology implementation. This teacher's pedagogy included research-based practices such a authentic problem-based learning, scientific inquiry, conceptual understanding of problem solving, connections to real-life situations and the use of metacognition in her practice. This study looked to determined if this implementation had an effect on student engagement and achievement; how the nature of technical and professional development impacted the implementation; and the barriers that were faced in creating a student-centered, technology rich approach to science. This qualitative study was conducted meeting the criteria of a case study of one teacher. The participant teacher's accounts of events through interviews were the primary source of data. In addition, multiple sources of information were also gathered. These included the teacher's reflective journal, student interviews, student focus groups, student artifacts, classroom observations, field notes, e-mail correspondences and students' test scores. This study proposes to contribute to the growing research evidence of implementation in the classroom and to identify specific obstacles that hinder success. The current state of education is calling for reform.
Ahmad, R; Kyratsis, Y; Holmes, A
2012-07-01
Health systems need efficient and effective innovation decisions to provide maximum benefit to patients, particularly in a climate of financial constraints. Although evidence-based innovations exist for helping to address healthcare-associated infections, the uptake and implementation of these is highly variable and in some cases very slow. To investigate innovation adoption decisions and implementation processes from an organizational perspective, focusing on the implications of stakeholder involvement during the innovation process. Thirty-eight technology adoption decisions and implementation processes were examined through 121 qualitative interviews in 12 National Health Service healthcare organizations across England. Stakeholder involvement varied across organizations with decisions highly exclusive to the infection prevention and control (IPC) team, to highly inclusive of wider organizational members. The context, including organizational culture, previous experience, and logistical factors influenced the level of stakeholder engagement. The timing of stakeholder involvement in the process impacted on: (i) the range of innovations considered; (ii) the technologies selected, and (iii) the success of technology implementation. Cases of non-adoption, discontinued adoption, and of successful implementation are presented to share learning. The potential benefits of stakeholder involvement for 'successful' innovation adoption are presented including a goal-oriented framework for involvement. Key stakeholder involvement can lead to innovation adoption and implementation compatible with structural and cultural contexts, particularly when involvement crosses the phases of initiation, decision-making and implementation. Involving members of the wider healthcare organization can raise the profile of IPC and reinforce efforts to make IPC everybody's business. Copyright © 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION (SITE) PROGRAM ANNUAL REPORT TO CONGRESS 2003
The Superfund Innovative Technology Evaluation (SITE) Program has successfully promoted the development, commercialization and implementation of innovative hazardous waste treatment technologies for 17 years. SITE offers a mechanism for conducting joint technology demonstration a...
78 FR 24749 - Health Information Technology Policy Committee Appointment
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-26
... GOVERNMENT ACCOUNTABILITY OFFICE Health Information Technology Policy Committee Appointment AGENCY... Recovery and Reinvestment Act of 2009 (ARRA) established the Health Information Technology Policy Committee to make recommendations on the implementation of a nationwide health information technology...
The Superfund Innovative Technology Evaluation Program Annual Report to Congress FY2004
The Superfund Innovative Technology Evaluation (SITE) Program has successfully promoted the development, commercialization, and implementation of innovative hazardous waste treatment technologies for 18 years. SITE offers a mechanism for conducting joint technology demonstration ...
Using technology to prevent adverse drug events in the intensive care unit.
Hassan, Erkan; Badawi, Omar; Weber, Robert J; Cohen, Henry
2010-06-01
Critically ill patients are particularly susceptible to adverse drug events (ADEs) due to their rapidly changing and unstable physiology, complex therapeutic regimens, and large percentage of medications administered intravenously. There are a wide variety of technologies that can help prevent the points of failure commonly associated with ADEs (i.e., the five "Rights": right patient; right drug; right route; right dose; right frequency). These technologies are often categorized by their degree of complexity to design and engineer and the type of error they are designed to prevent. Focusing solely on the software and hardware design of technology may over- or underestimate the degree of difficulty to avoid ADEs at the bedside. Alternatively, we propose categorizing technological solutions by identifying the factors essential for success. The two major critical success factors are: 1) the degree of clinical assessment required by the clinician to appropriately evaluate and disposition the issue identified by a technology; and 2) the complexity associated with effective implementation. This classification provides a way of determining how ADE-preventing technologies in the intensive care unit can be successfully integrated into clinical practice. Although there are limited data on the effectiveness of many technologies in reducing ADEs, we will review the technologies currently available in the intensive care unit environment. We will also discuss critical success factors for implementation, common errors made during implementation, and the potential errors using these systems.
Nurses' experiences using a nursing information system: early stage of technology implementation.
Lee, Ting-Ting
2007-01-01
Adoption of information technology in nursing practice has become a trend in healthcare. The impact of this technology on users has been widely studied, but little attention has been given to its influence at the beginning stage of implementation. Knowing the barriers to adopting technology could shorten this transition stage and minimize its negative influences. The purpose of this study was to explore nurses' experiences in the early stage of implementing a nursing information system. Focus groups were used to collect data at a medical center in Taiwan. The results showed that nurses had problems with the system's content design, had insufficient training, were concerned about data security, were stressed by added work, and experienced poor interdisciplinary cooperation. To smooth this beginning stage, the author recommends involving nurses early in the system design, providing sufficient training in keyboard entry skills, redesigning workflow, and improving interdisciplinary communication.
2010-01-13
The Department of Health and Human Services (HHS) is issuing this interim final rule with a request for comments to adopt an initial set of standards, implementation specifications, and certification criteria, as required by section 3004(b)(1) of the Public Health Service Act. This interim final rule represents the first step in an incremental approach to adopting standards, implementation specifications, and certification criteria to enhance the interoperability, functionality, utility, and security of health information technology and to support its meaningful use. The certification criteria adopted in this initial set establish the capabilities and related standards that certified electronic health record (EHR) technology will need to include in order to, at a minimum, support the achievement of the proposed meaningful use Stage 1 (beginning in 2011) by eligible professionals and eligible hospitals under the Medicare and Medicaid EHR Incentive Programs.
Monitoring of Overhead Transmission Lines: A Review from the Perspective of Contactless Technologies
NASA Astrophysics Data System (ADS)
Khawaja, Arsalan Habib; Huang, Qi; Khan, Zeashan Hameed
2017-12-01
This paper describes a comprehensive review of non-contact technologies for overhead power transmission lines. Due to ever increasing emphasis on reducing accidents and speeding up diagnosis for automatically controlled grids, real time remote sensing and actuation is the new horizon for smart grid implementation. The technology overview with emphasis on the practical implementation of advanced non-contact technologies is discussed in this paper while considering optimization of the high voltage transmission lines parameters. In case of fault, the voltage and the current exceed limits of operation and hence real time reporting for control and diagnosis is a critical requirement. This paper aims to form a strong foundation for control and diagnosis of future power distribution systems so that a practitioner or researcher can make choices for a workable solution in smart grid implementation based on non-contact sensing.
A Plan for Revolutionary Change in Gas Turbine Engine Control System Architecture
NASA Technical Reports Server (NTRS)
Culley, Dennis E.
2011-01-01
The implementation of Distributed Engine Control technology on the gas turbine engine has been a vexing challenge for the controls community. A successful implementation requires the resolution of multiple technical issues in areas such as network communications, power distribution, and system integration, but especially in the area of high temperature electronics. Impeding the achievement has been the lack of a clearly articulated message about the importance of the distributed control technology to future turbine engine system goals and objectives. To resolve these issues and bring the technology to fruition has, and will continue to require, a broad coalition of resources from government, industry, and academia. This presentation will describe the broad challenges facing the next generation of advanced control systems and the plan which is being put into action to successfully implement the technology on the next generation of gas turbine engine systems.
Implementation and Testing of Low Cost Uav Platform for Orthophoto Imaging
NASA Astrophysics Data System (ADS)
Brucas, D.; Suziedelyte-Visockiene, J.; Ragauskas, U.; Berteska, E.; Rudinskas, D.
2013-08-01
Implementation of Unmanned Aerial Vehicles for civilian applications is rapidly increasing. Technologies which were expensive and available only for military use have recently spread on civilian market. There is a vast number of low cost open source components and systems for implementation on UAVs available. Using of low cost hobby and open source components ensures considerable decrease of UAV price, though in some cases compromising its reliability. In Space Science and Technology Institute (SSTI) in collaboration with Vilnius Gediminas Technical University (VGTU) researches have been performed in field of constructing and implementation of small UAVs composed of low cost open source components (and own developments). Most obvious and simple implementation of such UAVs - orthophoto imaging with data download and processing after the flight. The construction, implementation of UAVs, flight experience, data processing and data implementation will be further covered in the paper and presentation.
Pettersson, Fanny L M
2013-01-01
In 2011, Umeå University in Sweden was facing its first attempt to transform the existing medical program into a regionalized medical program (RMP), supported by the use of digital technologies. The Swedish RMP means that students are distributed in geographically separated groups while doing their five clinical clerkship semesters. To provide medical students with ways of undertaking their theoretical studies when geographically distributed, digital technologies are used for educational and administrative purposes. In this article, the Swedish RMP will be described and related to previous international research on educating medical students in rural settings. The aim of this article was, from a management perspective, to understand if and how contradictions arise during the implementation process of the Swedish RMP, supported by digital technologies. Based on this analysis, a further aim was to discuss, from a management perspective, the possibilities and challenges for improvement of this medical educational practice, as well as to provide implications for other similar changes in medical programs internationally. To identify possible contradictions during the implementation process, ethnographically inspired observations were made during management work meetings, before and during the first regionalized semester. In addition, in-depth follow-up interviews were held in May and June 2011 with six management executives of the Swedish RMP, concerning their expectations and experiences of the implementation process. The qualitative and activity theory (AT)-inspired analysis resulted in the emergence of two main themes and seven sub-themes. The analysis suggests that a number of contradictions arose during the implementation process of the Swedish RMP. For instance, a contradiction constituted as a conflict between the university management and some teachers concerning how digital technologies and technology enhanced learning (TEL) could and should be used when educating medical students. In addition, due to the use of digital technologies the implementation process helped to reveal existing problems and tensions in educational practice, not previously visible to management. These included contradictions such as a lack of alignment in how course goals, teaching practices, and examinations should be carried out. Further, obsolete course content and overlap between courses and subjects were identified, leading to an overhaul of all semesters, not only those regionalized. This study showed how contradictions in educational practice arose when the Swedish RMP, supported by digital technologies, was implemented. These contradictions involve both possibilities and challenges for management to improve how and with what quality the Swedish RMP is conducted. A challenge for management is to find the most effective way to enhance up-take and use of the more interactive and innovative TEL-solutions. However, a possibility is that the regionalization process and implemented improvements may also influence non-regionalized semesters, with the potential to eventually increase the quality of the entire program.
NASA Astrophysics Data System (ADS)
Lesin, Yu V.; Hellmer, M. C.
2016-08-01
Among all industries in Kuzbass (Western Siberia, Russia) the coal industry provides the most environmental threat. However, the construction of new and maintenance of existing open pit mines do not often correspond to the tasks of improving the environmental safety of surface mining. So the article describes the use of innovative quarry waste water purifying technology implemented in Kuzbass open pit mine «Shestaki». This technology is based on using artificial filter arrays made of overburden rock.
Heavy Duty Roots Expander Heat Energy Recovery (HD-REHER)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Subramanian, Swami
2015-10-01
Eaton Corporation proposed a comprehensive project to develop and demonstrate advanced component technology that will reduce the cost of implementing Organic Rankine Cycle (ORC) Waste Heat Recovery (WHR) systems to Heavy-Duty Diesel engines, making adaptation of this fuel efficiency improving technology more commercially attractive to end-users in the next 5 to 10 year time period. Accelerated adaptation and implementation of new fuel efficiency technology into service is critical for reduction of fuel used in the commercial vehicle segment.
Impact of technology on cytology outcome in cervical cancer screening of young and older women.
Rask, J; Lynge, E; Franzmann, M; Hansen, B; Hjortebjerg, A; Rygaard, C; Schledermann, D; Wåhlin, A; Rebolj, M
2014-05-01
Little is known about age-dependent variation in outcomes of cervical cytology with modern technologies. This population-based study evaluated age-dependent changes after routine implementation of ThinPrep and SurePath technology in two independent laboratories, and controlled for time trends in a third laboratory using manually read conventional cytology continually. Data were collected from the Danish National Health Care Registers. For each laboratory, we compared proportions of abnormal cytology defined as atypical squamous cells of undetermined significance or worse (ASCUS+) by age and technology phase. The study included 489,960 cytological samples with no recent abnormality from women aged 23-59 years, routinely screened between 1998 and 2007. Implementation of SurePath liquid-based cytology (LBC) was followed by an increase in abnormal cytology in women aged 23-29 years from 4.6 to 6.1%, relative proportion (RP): 1.31 [95% confidence interval (CI): 1.08-1.61], and a decrease in women aged 45-59 years from 2.9 to 2.0%, RP: 0.71 (95% CI: 0.60-0.83). Implementation of ThinPrep LBC was followed by a decrease in abnormal cytology both in women aged 23-29 years from 7.7 to 6.8%, RP: 0.89 (95% CI: 0.78-1.02) and in women aged 45-59 years from 3.4 to 1.0%, RP: 0.30 (95% CI: 0.24-0.37). With implementation of imaging-assisted reading, regardless of the brand of technology, the proportion of abnormality increased by around 30% in all age groups (range from 19 to 41%). In the laboratory with unchanged technology no trends in abnormality proportions were observed. The impact of LBC implementation on cytological abnormality proportions varied considerably across age groups. © 2013 UICC.
Shade, Brandon C; Schiavo, Kellie; Rosenthal, Tami; Connelly, James T; Melchior, Richard W
2016-06-05
Recent advances in blood pump technology have led to an increased use of centrifugal pumps for prolonged extracorporeal membrane oxygenation (ECMO). Data from the Extracorporeal Life Support Organization confirms that many institutions have converted to centrifugal pumps after prior experience with roller pump technology. Centrifugal pump technology is more compact and may generate less heat and hemolysis than a conventional roller pump. Based on the potential advantages of centrifugal pumps, a decision was made institution-wide to convert to centrifugal pump technology in pediatric implementation of ECMO. Based on limited prior experience with centrifugal pumps, a multidisciplinary approach was used to implement this new technology. The new centrifugal pump (Sorin Revolution, Arvada, CO) was intended for ECMO support in the cardiac intensive care unit (CICU), the pediatric intensive care unit (PICU) and the neonatal intensive care unit (NICU). The perfusion team used their knowledge and expertise with centrifugal pumps to create the necessary teaching tools and interactive training sessions for the technical specialists who consisted primarily of registered nurses and respiratory therapists. The first phase consisted of educating all personnel involved in the care of the ECMO patient, followed by patient implementation in the CICU, followed by the PICU and NICU. The institution-wide conversion took several months to complete and was well received among all disciplines in the CICU and PICU. The NICU personnel did use the centrifugal pump circuit, but decided to revert back to using the roller pump technology. A systematic transition from roller pump to centrifugal pump technology with a multidisciplinary team can ensure a safe and successful implementation. © The Author(s) 2016.
Yen, Po-Yin; McAlearney, Ann Scheck; Sieck, Cynthia J; Hefner, Jennifer L; Huerta, Timothy R
2017-09-07
In past years, policies and regulations required hospitals to implement advanced capabilities of certified electronic health records (EHRs) in order to receive financial incentives. This has led to accelerated implementation of health information technologies (HIT) in health care settings. However, measures commonly used to evaluate the success of HIT implementation, such as HIT adoption, technology acceptance, and clinical quality, fail to account for complex sociotechnical variability across contexts and the different trajectories within organizations because of different implementation plans and timelines. We propose a new focus, HIT adaptation, to illuminate factors that facilitate or hinder the connection between use of the EHR and improved quality of care as well as to explore the trajectory of changes in the HIT implementation journey as it is impacted by frequent system upgrades and optimizations. Future research should develop instruments to evaluate the progress of HIT adaptation in both its longitudinal design and its focus on adaptation progress rather than on one cross-sectional outcome, allowing for more generalizability and knowledge transfer. ©Po-Yin Yen, Ann Scheck McAlearney, Cynthia J Sieck, Jennifer L Hefner, Timothy R Huerta. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 07.09.2017.
NASA Astrophysics Data System (ADS)
Akhbari, M.
2015-12-01
Water, energy, and food are closely bound in consumption and production patterns. To increase resource efficiency and productivity in a sustainable fashion, co-management of water, energy, and food resources is becoming inevitable. These co-management schemes require implementation of nexus-based approaches, which takes the interconnections of water, energy, and food systems into account and considers that development in one area may have major effects on others. While society, economy and environment are the action areas to implement a nexus approach, finance, governance, infrastructure and technology can create solutions. Existing obstacles in the action areas and challenges associated with creating solutions increase the complexities to develop nexus-based approaches and complicate their implementation. This study, identifies existing social, economic, and environmental obstacles, financial demands and constraints, shortcomings in governance, and infrastructure problems in the United States as the main challenges that need to be overcome. Then, it will be discussed how advanced technology could be employed to facilitate implementation of nexus-based approaches, followed by providing some recommendations to enable institutions to employ new technology, overcome existing obstacles, and address challenges in order to implement nexus-based management approaches.
DEMONSTRATION AND EVALUATION OF INNOVATIVE REMEDIATION TECHNOLOGIES THROUGH THE EPA SITE PROGRAM
The Superfund Innovative Technology Evaluation (SITE) Program has successfuly promoted the development, commercialization and implementation of innovative hazardous waste treatment technologies for 18 years. SITE offers a mechanism for conducting joint technology demonstration an...
48 CFR 39.103 - Modular contracting.
Code of Federal Regulations, 2010 CFR
2010-10-01
... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.103 Modular contracting. (a) This section implements Section 5202, Incremental Acquisition of Information Technology, of the Clinger-Cohen... technology. Consistent with the agency's information technology architecture, agencies should, to the maximum...
SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM ANNUAL REPORT TO CONGRESS FY 1996
The Superfund Innovative Technology Evaluation (SITE) Program has been successfully promoting the development, commercialization and implementation of innovative hazardous waste treatment technologies for more than 10 years. SITE offers a mechanism for conducting joint technology...
SUPERFUND INNOVTIVE TECHNOLOGY EVALUATION PROGRAM ANNUAL REPORT TO CONGRESS FY 1997
The Superfund Innovative Technology Evaluation (SITE) Program has successfully promoted the development, commercialization and implementation of innovative hazardous waste treatment technologies for more than 12 years. SITE offers a mechanism for conducting joint technology demon...
THE SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM ANNUAL REPORT TO CONGRESS FY1999
The Superfund Innovative Technology Evaluation (SITE) Program has successfully promoted the development, commercialization and implementation of innovative hazardous waste treatment technologies for more than 14 years. SITE offers a mechanism for conducting joint technology demon...
Potential applications of video technology for traffic management and safety in Alabama
DOT National Transportation Integrated Search
2002-11-25
Video technology applications for traffic management and safety are being implemented by state and local government agencies in Alabama. This technology offers both tangible and intangible benefits. Although video technology provides many benefits, i...
ERIC Educational Resources Information Center
Nworji, Alexander O.
2013-01-01
Most organizations spend millions of dollars due to the impact of improperly implemented database application systems as evidenced by poor data quality problems. The purpose of this quantitative study was to use, and extend, the technology acceptance model (TAM) to assess the impact of information quality and technical quality factors on database…
A Literature Review: The Effect of Implementing Technology in a High School Mathematics Classroom
ERIC Educational Resources Information Center
Murphy, Daniel
2016-01-01
This study is a literature review to investigate the effects of implementing technology into a high school mathematics classroom. Mathematics has a hierarchical structure in learning and it is essential that students get a firm understanding of mathematics early in education. Some students that miss beginning concepts may continue to struggle with…
ERIC Educational Resources Information Center
Gregory, Mary Sarah-Jane; Lodge, Jason Michael
2015-01-01
The effect of technology-enhanced learning (TEL) strategies in higher education has arguably been transformative despite the not-insignificant barriers existing in this context. Throughout the discourse very little attention has been paid to those primarily responsible for this implementation--academic teaching staff. This paper aims to highlight…
ERIC Educational Resources Information Center
Cooper, Calvin H., Jr.
2014-01-01
Consistent with a recognized challenge across the United States, the local problem addressed in this study was teachers' inability to implement new technologies in the classroom. Professional development is the channel through which teachers improve, and high-quality professional development has been shown to enhance teacher efficacy. Professional…
A Case Study of a National University Research Project and Its Technological Innovation
ERIC Educational Resources Information Center
Ziegel, Melina
2012-01-01
This case study examined the implementation of a major research endeavor in an institution of higher education, Trinity College, Dublin, in Ireland, with particular focus on the change process during the initiation of the project and the subsequent needs assessment and implementation of technological solutions. This study identified the stages,…
ERIC Educational Resources Information Center
Schwedler, Jennifer Green
2017-01-01
Enterprise software implementations are subject to high failure rates. Organizations of higher education can be particularly resistant to technology implementations as they can be perceived as eroding the traditions of the institution. The California State University (CSU) system is moving into a new phase of data-driven accountability for…
Technical Feasibility of a Mobile Context-Aware (Social) Learning Schedule Framework
ERIC Educational Resources Information Center
Yau, Jane Y. K.; Joy, Mike
2013-01-01
The purpose of this paper is to show the technical feasibility of implementing their mobile context-aware learning schedule (mCALS) framework as a software application on a mobile device using current technologies, prior to its actual implementation. This process draws a set of compatible mobile and context-aware technologies at present and can be…
ERIC Educational Resources Information Center
Odili, John Nwanibeze; Ebisine, Sele Sylvester; Ajuar, Helen Nwakaife
2011-01-01
The study investigated teachers' involvement in implementing the basic science and technology curriculum in primary schools in WSLGA (Warri South Local Government Area) of Delta State. It sought to identify the availability of the document in primary schools and teachers' knowledge of the objectives and activities specified in the curriculum.…
ERIC Educational Resources Information Center
Almekhlafi, Abdurrahman Ghaleb
2005-01-01
Teachers' clear perceptions of technology use and competence in planning and implementation affect their attitudes towards using technology in general and in the classroom in particular (Almekhlafi, 1999). However, the number of research studies to inform implementation of Web-based instruction (WBI) has been low and the interest in student…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-02
... Promulgation of Implementation Plans; Texas; Reasonably Available Control Technology for the 1997 8-Hour Ozone... (SIP) for the Houston/Galveston/ Brazoria (HGB) 1997 8-Hour ozone nonattainment Area (Area). The HGB... Room between the hours of 8:30am and 4:30 p.m. weekdays except for legal holidays. Contact the person...
ERIC Educational Resources Information Center
Bolt, Daniel M.; Ysseldyke, Jim; Patterson, Michael J.
2010-01-01
A three-level variance decomposition analysis was used to examine the sources of variability in implementation of a technology-enhanced progress monitoring system within each year of a 2-year study using a randomized-controlled design. We show that results of technology-enhanced progress monitoring are not necessarily a measure of student…
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services (ED), Washington, DC. Div. of Innovation and Development.
This paper reviews and synthesizes information on the administrative aspects of technology implementation in special education, based on the findings of eight federally funded projects sponsored by the Division of Innovation and Development of the Office of Special Education Programs. Three of the projects specifically focused on administrative…
FAILSAFE Health Management for Embedded Systems
NASA Technical Reports Server (NTRS)
Horvath, Gregory A.; Wagner, David A.; Wen, Hui Ying; Barry, Matthew
2010-01-01
The FAILSAFE project is developing concepts and prototype implementations for software health management in mission- critical, real-time embedded systems. The project unites features of the industry-standard ARINC 653 Avionics Application Software Standard Interface and JPL s Mission Data System (MDS) technology (see figure). The ARINC 653 standard establishes requirements for the services provided by partitioned, real-time operating systems. The MDS technology provides a state analysis method, canonical architecture, and software framework that facilitates the design and implementation of software-intensive complex systems. The MDS technology has been used to provide the health management function for an ARINC 653 application implementation. In particular, the focus is on showing how this combination enables reasoning about, and recovering from, application software problems.
Understanding managerial behaviour during initial steps of a clinical information system adoption
2011-01-01
Background While the study of the information technology (IT) implementation process and its outcomes has received considerable attention, the examination of pre-adoption and pre-implementation stages of configurable IT uptake appear largely under-investigated. This paper explores managerial behaviour during the periods prior the effective implementation of a clinical information system (CIS) by two Canadian university multi-hospital centers. Methods Adopting a structurationist theoretical stance and a case study research design, the processes by which CIS managers' patterns of discourse contribute to the configuration of the new technology in their respective organizational contexts were longitudinally examined over 33 months. Results Although managers seemed to be aware of the risks and organizational impact of the adoption of a new clinical information system, their decisions and actions over the periods examined appeared rather to be driven by financial constraints and power struggles between different groups involved in the process. Furthermore, they largely emphasized technological aspects of the implementation, with organizational dimensions being put aside. In view of these results, the notion of 'rhetorical ambivalence' is proposed. Results are further discussed in relation to the significance of initial decisions and actions for the subsequent implementation phases of the technology being configured. Conclusions Theoretical and empirically grounded, the paper contributes to the underdeveloped body of literature on information system pre-implementation processes by revealing the crucial role played by managers during the initial phases of a CIS adoption. PMID:21682885
Sligo, Judith; Gauld, Robin; Roberts, Vaughan; Villa, Luis
2017-01-01
Information technology is perceived as a potential panacea for healthcare organisations to manage pressure to improve services in the face of increased demand. However, the implementation and evaluation of health information systems (HIS) is plagued with problems and implementation shortcomings and failures are rife. HIS implementation is complex and relies on organisational, structural, technological, and human factors to be successful. It also requires reflective, nuanced, multidimensional evaluation to provide ongoing feedback to ensure success. This article provides a comprehensive review of the literature about evaluating and implementing HIS, detailing the challenges and recommendations for both evaluators and healthcare organisations. The factors that inhibit or promote successful HIS implementation are identified and effective evaluation strategies are described with the goal of informing teams evaluating complex HIS. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Information technology from novice to expert: implementation implications.
Courtney, Karen L; Alexander, Gregory L; Demiris, George
2008-09-01
This paper explores how the Novice-to-Expert Nursing Practice framework can illuminate the challenges of and opportunities in implementing information technology (IT), such as clinical decision support systems (CDSS), in nursing practice. IT implementation in health care is increasing; however, substantial costs and risks remain associated with these projects. The theoretical framework of Novice-to-Expert Nursing Practice was applied to current design and implementation literature for CDSS. Organizational policies and CDSS design affect implementation and user adoption. Nursing CDSS can improve the overall quality of care when designed for the appropriate end-user group and based on a knowledge base reflecting nursing expertise. Nurse administrators can positively influence CDSS function and end-user acceptance by participating in and facilitating staff nurse involvement in IT design, planning and implementation. Specific steps for nurse administrators and managers are included in this paper.
Revolution in Communication Technologies: Impact on Distance Education
ERIC Educational Resources Information Center
Rajesh, M.
2015-01-01
Information and Communication Technologies have transformed the way the world lives and thinks. Education, especially, Distance Education is no different. While the technologies per se are an important factor, the social milieus in which these technologies are implemented are equally important. Technological convergence in the Indian context…
ERIC Educational Resources Information Center
Moore, Pamela Richardson
2012-01-01
An understanding of school administrators' personal innovativeness relative to technology acceptance is essential to the implementation of technology programs. School administrators serve as visionary instructional leaders whose beliefs about technology impact technology integration at their schools. The purpose of the "ex post…
On Study of Teaching Reform of Organic Chemistry Course in Applied Chemical Industry Technology
NASA Astrophysics Data System (ADS)
Zhang, Yunshen
2017-11-01
with the implementation of new curriculum reform, the education sees great changes in teaching methods. Teaching reform is profound in organic chemistry course in applied chemical industry technology. However, many problems which have never been noticed before occur when reform programs are implemented which harm students’ ability for learning and enthusiasm in side face. This paper proposes reform measures like combining theory and practice, improving professional quality, supplementing professional needs and integrating teaching into life after analyzing organic chemistry course teaching in applied chemical industry technology currently, hoping to play a role of reference for organic chemistry course teaching reform in applied chemical industry technology.
Information technology and behavioral medicine: impact on autism treatment & research.
Oberleitner, Ron; Laxminarayan, Swamy
2004-01-01
Families, clinicians and researchers involved with varying neurological disorders face amazing challenges to understand, treat, and assist the people they are serving. Autism brings unique challenges and serves as an important model for the application of important concepts in information technology and telemedicine. The rising incidence of autism with limited professional resources has led to more consideration for using information technology and related specialties to link families and professionals, and to implement strategies which implement information technology to improve the outcomes for individuals with autism and their families. These are reviewed in context of the unique health, education, and the research issues facing those dealing with autism.
Technological inductive power transfer systems
NASA Astrophysics Data System (ADS)
Madzharov, Nikolay D.; Nemkov, Valentin S.
2017-05-01
Inductive power transfer is a very fast expanding technology with multiple design principles and practical implementations ranging from charging phones and computers to bionic systems, car chargers and continuous power transfer in technological lines. Only a group of devices working in near magnetic field is considered. This article is devoted to overview of different inductive power transfer (IPT) devices. The review of literature in this area showed that industrial IPT are not much discussed and examined. The authors have experience in design and implementation of several types of IPTs belonging to wireless automotive chargers and to industrial application group. Main attention in the article is paid to principles and design of technological IPTs
Networks: A Review of Their Technology, Architecture, and Implementation.
ERIC Educational Resources Information Center
Learn, Larry L.
1988-01-01
This overview of network-related technologies covers network elements, analog and digital signals, transmission media and their characteristics, equipment certification, multiplexing, network types, access technologies, network architectures local-area network technologies and attributes, protocols, internetworking, fiber optics versus satellites,…
48 CFR 939.7002 - Contractor acquisition of information technology.
Code of Federal Regulations, 2013 CFR
2013-10-01
... information technology. 939.7002 Section 939.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7002 Contractor acquisition of information technology. (a) Management and operating (M&O...
48 CFR 939.7002 - Contractor acquisition of information technology.
Code of Federal Regulations, 2014 CFR
2014-10-01
... information technology. 939.7002 Section 939.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7002 Contractor acquisition of information technology. (a) Management and operating (M&O...
45 CFR 170.302 - General certification criteria for Complete EHRs or EHR Modules.
Code of Federal Regulations, 2013 CFR
2013-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.302 General certification criteria for Complete EHRs or EHR Modules...
45 CFR 170.302 - General certification criteria for Complete EHRs or EHR Modules.
Code of Federal Regulations, 2014 CFR
2014-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.302 General certification criteria for Complete EHRs or EHR Modules...
48 CFR 939.7002 - Contractor acquisition of information technology.
Code of Federal Regulations, 2011 CFR
2011-10-01
... information technology. 939.7002 Section 939.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7002 Contractor acquisition of information technology. (a) Management and operating (M&O...
45 CFR 170.302 - General certification criteria for Complete EHRs or EHR Modules.
Code of Federal Regulations, 2011 CFR
2011-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.302 General certification criteria for Complete EHRs or EHR Modules...
45 CFR 170.302 - General certification criteria for Complete EHRs or EHR Modules.
Code of Federal Regulations, 2012 CFR
2012-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.302 General certification criteria for Complete EHRs or EHR Modules...
48 CFR 939.7002 - Contractor acquisition of information technology.
Code of Federal Regulations, 2012 CFR
2012-10-01
... information technology. 939.7002 Section 939.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7002 Contractor acquisition of information technology. (a) Management and operating (M&O...
48 CFR 939.7002 - Contractor acquisition of information technology.
Code of Federal Regulations, 2010 CFR
2010-10-01
... information technology. 939.7002 Section 939.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7002 Contractor acquisition of information technology. (a) Management and operating (M&O...
45 CFR 170.302 - General certification criteria for Complete EHRs or EHR Modules.
Code of Federal Regulations, 2010 CFR
2010-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Certification Criteria for Health Information Technology § 170.302 General certification criteria for Complete EHRs or EHR Modules...
Supporting the spread of health technology in community services.
Sitton-Kent, Lucy; Humphreys, Catriona; Miller, Phillip
2018-03-02
Health technology has been proposed as a route to financial savings and improved patient safety for many years within the NHS. Nurses have a key role to play in transforming care through such technology but, despite high-level endorsement, implementation of health technology has been uneven across NHS community services. This article looks at three promising applications of health technology in community nursing: mobile access to digital care records; digital imaging; and remote face-to-face consultations. Current evidence for these technologies gives some indication of what is required before health technologies can benefit patients. Rapidly changing health technologies make it difficult for community services to make fully informed decisions when implementing them. There are challenges in predicting the full financial and efficiency impacts, in making robust estimates of costs and workload implications and in anticipating the effects on patient care and staff experience. Despite these problems, there is mounting evidence of the benefits of technological innovations available to community nurses and their patients.
Research and technology 1987 annual report of the Kennedy Space Center
NASA Technical Reports Server (NTRS)
1987-01-01
As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing increasing emphasis on the Center's research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects of this Kennedy Space Center 1987 Annual Report.
2012-09-04
With this final rule, the Secretary of Health and Human Services adopts certification criteria that establish the technical capabilities and specify the related standards and implementation specifications that Certified Electronic Health Record (EHR) Technology will need to include to, at a minimum, support the achievement of meaningful use by eligible professionals, eligible hospitals, and critical access hospitals under the Medicare and Medicaid EHR Incentive Programs beginning with the EHR reporting periods in fiscal year and calendar year 2014. This final rule also makes changes to the permanent certification program for health information technology, including changing the program's name to the ONC HIT Certification Program.
NASA Technical Reports Server (NTRS)
Horsham, Gary A. P.
1992-01-01
This report presents a strategic analysis and implementation plan for NASA's Office of Commercial Programs (OCP), Technology Transfer Division's (TTD), Technology Transfer Program. The main objectives of this study are to: (1) characterize the NASA TTD's environment and past organizational structure; (2) clearly identify current and prospective programmatic efforts; (3) determine an evolutionary view of an organizational structure which could lead to the accomplishment of NASA's future technology transfer aims; and (4) formulate a strategy and plan to improve NASA's (and other federal agencies) ability to transfer technology to the non-aerospace sectors of the U.S. economy. The planning horizon for this study extends through the remainder of the 1990s to the year 2000.
Exploring Students' Technology Acceptance in College Developmental Mathematics
ERIC Educational Resources Information Center
Williams, Handan
2012-01-01
Technology has become a large component of teaching and learning in mathematics education. Gaining insight into students' technology acceptance factors is a crucial step in understanding instructional design and implementation of technology-based learning programs. Despite the widespread use of technology in education, few research efforts…
ERIC Educational Resources Information Center
Del Favero, Marietta; Hinson, Janice M.
2007-01-01
The press for implementing technology based instructional delivery systems in community and technical colleges is well documented. Yet faculty face numerous challenges in integrating technology into instruction (AL-Bataineh & Brooks, 2003; Groves & Zemel, 2000; Khoury, 1997). Stimulating faculty ownership in technology, diffusion of technology use…
A Portal of Educational Resources: Providing Evidence for Matching Pedagogy with Technology
ERIC Educational Resources Information Center
Di Blas, Nicoletta; Fiore, Alessandro; Mainetti, Luca; Vergallo, Roberto; Paolini, Paolo
2014-01-01
The TPACK (Technology, Pedagogy and Content Knowledge) model presents the three types of knowledge that are necessary to implement a successful technology-based educational activity. It highlights how the intersections between TPK (Technological Pedagogical Knowledge), PCK (Pedagogical Content Knowledge) and TCK (Technological Content Knowledge)…
3D Holographic Technology and Its Educational Potential
ERIC Educational Resources Information Center
Lee, Hyangsook
2013-01-01
This article discusses a number of significant developments in 3D holographic technology, its potential to revolutionize aspects of teaching and learning, and challenges of implementing the technology in educational settings.
45 CFR 170.470 - Effect of revocation on the certifications issued to complete EHRs and EHR Modules.
Code of Federal Regulations, 2011 CFR
2011-10-01
... HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary...
45 CFR 170.470 - Effect of revocation on the certifications issued to complete EHRs and EHR Modules.
Code of Federal Regulations, 2013 CFR
2013-10-01
... HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary...
45 CFR 170.101 - Applicability.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY General Provisions § 170.101 Applicability. The standards...
45 CFR 170.101 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY General Provisions § 170.101 Applicability. The standards...
45 CFR 170.101 - Applicability.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY General Provisions § 170.101 Applicability. The standards...
45 CFR 170.470 - Effect of revocation on the certifications issued to complete EHRs and EHR Modules.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary...
45 CFR 170.101 - Applicability.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY General Provisions § 170.101 Applicability. The standards...
45 CFR 170.470 - Effect of revocation on the certifications issued to complete EHRs and EHR Modules.
Code of Federal Regulations, 2010 CFR
2010-10-01
... HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary...
45 CFR 170.470 - Effect of revocation on the certifications issued to complete EHRs and EHR Modules.
Code of Federal Regulations, 2012 CFR
2012-10-01
... HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary...
45 CFR 170.101 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY General Provisions § 170.101 Applicability. The standards...
Slater, Helen; Briggs, Andrew; Stinson, Jennifer; Campbell, Jared M
2017-08-01
The objective of this review is to systematically identify, review and synthesize relevant qualitative research on end user and implementer experiences of mobile health (mHealth) technologies developed for noncommunicable chronic disease management in young adults. "End users" are defined as young people aged 15-24 years, and "implementers" are defined as health service providers, clinicians, policy makers and administrators.The two key questions we wish to systematically explore from identified relevant qualitative studies or studies with qualitative components are.
New technology implementation: Technical, economic and political factors
NASA Technical Reports Server (NTRS)
Dean, J. W., Jr.; Susman, G. I.; Porter, P. S.
1985-01-01
An analysis is presented of the process of implementing advanced manufacturing technology, based on studies of numerous organizations. This process is seen as consisting of a series of decisions with technical, economic, and political objectives. Frequency decisions involve specifications, equipment, resources/organization, and location. Problems in implementation are viewed as resulting from tradeoffs among the objectives, the tendency of decision makers to emphasize some objectives at the expense of others, and the propensity of problems to spread from one area to another. Three sets of recommendations, based on this analysis, are presented.
A New Approach to Geoengineering: Manna From Heaven
NASA Astrophysics Data System (ADS)
Ellery, Alex
2015-04-01
Geo-engineering, although controversial, has become an emerging factor in coping with climate change. Although most are terrestrial-based technologies, I focus on a space-based approach implemented through a solar shield system. I present several new elements that essentially render the high-cost criticism moot. Of special relevance are two seemingly unrelated technologies - the Resource Prospector Mission (RPM) to the Moon in 2018 that shall implement a technology demonstration of simple material resource extraction from lunar regolith, and the emergence of multi-material 3D printing technology that promises unprecedented robotic manufacturing capabilities. My research group has begun theoretical and experimentation work in developing the concept of a 3D printed electric motor system from lunar-type resources. The electric motor underlies every universal mechanical machine. Together with 3D printed electronics, I submit that this would enable self-replicating machines to be realised. A detailed exposition on how this may be achieved will be outlined. Such self-replicating machines could construct the spacecraft required to implement a solar shield and solar power satellites in large numbers from lunar resources with the same underlying technologies at extremely low cost.
Electronic commerce: beyond the euphoria.
Healy, J L; DeLuca, J M
2000-01-01
As the center of considerable media attention, case study articles, vendor research, and development efforts, electronic commerce technology is entering healthcare and having a profound effect. The simple truth, however, is that after the drama and excitement begins to wear off, completing a successful e-commerce implementation remains good old-fashioned hard, sometimes monotonous work. To be successful, e-commerce technologies must be planned and implemented with rigorous project standards, and incorporated with significant process and workflow reengineering to actually return significant value to the organization. This article briefs readers on the organizational issues they must consider in evaluating e-commerce readiness--cultural, executive and technological factors that either support or inhibit project and technology success. Readers will be left with the tools to conduct an electronic commerce "readiness assessment" to evaluate the immediate, mid- and long-term potential of electronic commerce; practical remediation strategies for better preparing the organization for the changes inherent in moving to an e-commerce-enabled business model; and comments from the field--advice from organizations that have successfully implemented e-commerce technologies into their ongoing operations.
Client-Server Connection Status Monitoring Using Ajax Push Technology
NASA Technical Reports Server (NTRS)
Lamongie, Julien R.
2008-01-01
This paper describes how simple client-server connection status monitoring can be implemented using Ajax (Asynchronous JavaScript and XML), JSF (Java Server Faces) and ICEfaces technologies. This functionality is required for NASA LCS (Launch Control System) displays used in the firing room for the Constellation project. Two separate implementations based on two distinct approaches are detailed and analyzed.
1994-09-01
implementation of the services necessary to support transparent "information pull " operation of decision support systems. This infrastructure will be implemented...technology. Some aspects of this area such as user- pull , mobile and highly distributed operation, bandwidth needs and degree of securihy are Dol)-driven...by a variety of statutory requirements. R&D will provide enhanced mission effectiveness and maintenance of fragile ecosystems. The goalis to develop
ERIC Educational Resources Information Center
Mergendoller, John R.; And Others
This evaluation report describes program implementation, computer acquisition and placement, and computer use during the second year (1991-92) of the Utah Educational Technology Initiative (ETI). In addition, it discusses the various ways computers are used in Utah schools and reports the opinions and experiences of ETI coordinators in the 12…
ERIC Educational Resources Information Center
Bednarz, Sarah Witham; van der Schee, Joop
2006-01-01
Since its inception in the early 1990s, geographic information science and its related technology, geographic information systems (GIS), have diffused slowly into select groups of K-12 classrooms worldwide. The technology has not been adopted at a rate commensurate with expectations. The purpose of this article is to explore GIS implementation by…
ERIC Educational Resources Information Center
Al Bataineh, Mohammad; Anderson, Sharon
2015-01-01
This study used a cross-sectional, ten-point Likert-type scale survey design, to examine the perception of Jordanian seventh to twelfth-grade social studies teachers of the competency needed for technology implementation in their classrooms. The instrument for this study was a modified version of a survey developed by Kelly (2003) called the…
ERIC Educational Resources Information Center
Velickovic, Sonja; Stošic, Lazar
2016-01-01
This study explores the issue of the preparedness of educators to realize the contents of the PPP (Preschool Preparatory Program) from the point of view of digitalization and informatization of the society. The authors are in favour of the implementation of modern educational technology in the process of educating preschool children with the aim…
ERIC Educational Resources Information Center
Gökoglu, Seyfullah; Çakiroglu, Ünal
2017-01-01
The aim of this case study is to evaluate the effect of mentors on teachers' technology integration process into their classrooms. In integration process, interactions between the mentors and the teachers are implemented in terms of Systems-Based Mentoring Model (SBMM). Mentors' leadership roles were determined and changes in teachers' technology…
ERIC Educational Resources Information Center
New York State Education Dept., Albany. Div. of Elementary and Secondary Education Planning.
This document presents four action recommendations for implementing the long-range plan for technology in elementary and secondary education in New York state and three options or different strategies for implementing each of the action recommendations. The tables and bar graphs which make up the major part of this report indicate the extent to…
ERIC Educational Resources Information Center
Ntemngwa, Celestin; Oliver, J. Steve
2018-01-01
The research study reported here was conducted to investigate the implementation of integrated STEM lessons within courses that have a single subject science focus. The purpose also included development of a pedagogical theory. This technology-based teaching was conceptualized by school administrators and teachers in order to provide middle school…
ERIC Educational Resources Information Center
Bennett, Jeannine B.
2012-01-01
This study addressed the problems associated with users' understanding, accepting, and complying with requirements of security-oriented solutions. The goal of the research was not to dispute existing theory on IT project implementations, but rather to further the knowledge on the topic of technology user acceptance of security-oriented IT…
ERIC Educational Resources Information Center
Habib, Laurence; Johannesen, Monica
2014-01-01
This article presents the results of a study using both quantitative and qualitative data to uncover the extent and nature of the involvement of academic staff in the processes of acquisition and implementation of educational technologies. Actor-network theory (ANT) is used to inform the design of the study and the analysis of the data. Three main…
ERIC Educational Resources Information Center
Lonsdale, Helen C.; McWilliams, Alfred E., Jr.
The Program Component of the Satellite Technology Demonstration (STD) developed the programing for a television series on career planning for junior high school students. A program called "Time Out" was designed, developed, and implemented to be broadcast throughout the Rocky Mountain States. A staff of educators and communicators…
Professional development of Russian HEIs' management and faculty in CDIO standards application
NASA Astrophysics Data System (ADS)
Chuchalin, Alexander; Malmqvist, Johan; Tayurskaya, Marina
2016-07-01
The paper presents the approach to complex training of managers and faculty staff for system modernisation of Russian engineering education. As a methodological basis of design and implementation of the faculty development programme, the CDIO (Conceive-Design-Implement-Operate) Approach was chosen due to compliance of its concept to the purposes and tasks of engineering education development in Russia. The authors describe the structure, the content and implementation technology of the programme designed by Tomsk Polytechnic University and Skolkovo Institute of Science and Technology with the assistance of Chalmers University of Technology and KTH Royal Institute of Technology and other members of the CDIO Initiative. The programme evaluation based on the questionnaire results showed that the programme content is relevant, has high practical value and high level of novelty for all categories of participants. Therefore, the CDIO approach was recommended for implementation to improve various elements of the engineering programme such as learning outcomes, content and structure, teaching, learning and assessment methods. Besides, the feedback results obtained through programme participants' survey contribute to identification of problems preventing development of engineering education in Russia and thus serve as milestones for further development of the programme.
School-Based Technology Use Planning.
ERIC Educational Resources Information Center
Cradler, John
1994-01-01
Describes how to conduct systematic planning for technology use. The components of an effective technology use plan, derived from a comprehensive study of school-based technology, are given. Planning development, implementation, and evaluation steps are provided. Ten planning resource books are listed. (Contains five references.) (KRN)
Administrator's Guide to Technology: Planning, Funding & Implementation.
ERIC Educational Resources Information Center
Aspen Education Development Group, Gaithersburg, MD.
This document provides guidelines for administrators related to instructional technology and planning. Chapter 1 discusses planning, including developing a technology plan, facility assessment, e-rate planning, formation of a technology committee, budget planning, and hardware/software replacement plan and costs. Chapter 2 addresses…
45 CFR 170.455 - Testing and certification to newer versions of certain standards.
Code of Federal Regulations, 2010 CFR
2010-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification... Technology may be upgraded to comply with newer versions of an adopted minimum standard accepted by the...
45 CFR 170.455 - Testing and certification to newer versions of certain standards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification... Technology may be upgraded to comply with newer versions of an adopted minimum standard accepted by the...
45 CFR 170.455 - Testing and certification to newer versions of certain standards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification... Technology may be upgraded to comply with newer versions of an adopted minimum standard accepted by the...
45 CFR 170.455 - Testing and certification to newer versions of certain standards.
Code of Federal Regulations, 2011 CFR
2011-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification... Technology may be upgraded to comply with newer versions of an adopted minimum standard accepted by the...
45 CFR 170.455 - Testing and certification to newer versions of certain standards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification... Technology may be upgraded to comply with newer versions of an adopted minimum standard accepted by the...
48 CFR 39.103 - Modular contracting.
Code of Federal Regulations, 2014 CFR
2014-10-01
... increments to take advantage of any evolution in technology or needs that occur during implementation and use... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.103 Modular contracting. (a) This... technology. Consistent with the agency's information technology architecture, agencies should, to the maximum...
77 FR 52766 - Technology and Trading Roundtable
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-30
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-67725; File No. 4-652] Technology and Trading... ``Technology and Trading: Promoting Stability in Today's Markets'' to discuss ways to promote stability in..., implement, and manage complex and inter-connected trading technologies. The roundtable discussion will be...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-30
... DEPARTMENT OF EDUCATION Applications for New Awards; Educational Technology, Media, and Materials for Individuals With Disabilities Program--Stepping-Up Technology Implementation AGENCY: Office of... Information Educational Technology, Media, and Materials for Individuals With Disabilities Program--Stepping...
Code of Federal Regulations, 2013 CFR
2013-10-01
... HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY ONC HIT...
45 CFR 170.505 - Correspondence.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY ONC HIT Certification Program § 170.505 Correspondence. (a...
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.402 Definitions. For...
45 CFR 170.401 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Welfare Department of Health and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.401 Applicability...
45 CFR 170.405 - Correspondence.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.405 Correspondence. (a...
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY ONC HIT Certification Program § 170.502 Definitions. For the...
45 CFR 170.401 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.401 Applicability...
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.420 Application. The...
Code of Federal Regulations, 2012 CFR
2012-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Permanent Certification Program for HIT § 170.502 Definitions. For...
45 CFR 170.505 - Correspondence.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY ONC HIT Certification Program § 170.505 Correspondence. (a...