Science.gov

Sample records for including resistive mhd

  1. Magnetic reconnection in Hall-MHD including electron inertia

    NASA Astrophysics Data System (ADS)

    Gomez, D. O.; Andres, N.; Martin, L. N.; Dmitruk, P.

    2013-12-01

    Magnetic reconnection is an important energy conversion process in highly conducting plasmas, such as those present in the solar corona or in planetary magnetospheres. Within the framework of resistive one-fluid MHD, the Sweet-Parker model leads to extremely low reconnection rates for virtually all space physics applications. Kinetic plasma effects introduce new spatial and temporal scales into the theoretical description, which might significantly increase the reconnection rates. Within the more general framework of two-fluid MHD for a fully ionized hydrogen plasma, we retain the effects of the Hall current and electron inertia. We performed 2.5D Hall MHD simulations including electron inertia using a pseudo-spectral code which yields exact conservation (to round-off errors) of all the ideal invariants. We obtain finite reconnection rates even in the case of zero resistivity, thus showing the important influence of the electron inertia.

  2. Problems in nonlinear resistive MHD

    SciTech Connect

    Turnbull, A.D.; Strait, E.J.; La Haye, R.J.; Chu, M.S.; Miller, R.L.

    1998-12-31

    Two experimentally relevant problems can relatively easily be tackled by nonlinear MHD codes. Both problems require plasma rotation in addition to the nonlinear mode coupling and full geometry already incorporated into the codes, but no additional physics seems to be crucial. These problems discussed here are: (1) nonlinear coupling and interaction of multiple MHD modes near the B limit and (2) nonlinear coupling of the m/n = 1/1 sawtooth mode with higher n gongs and development of seed islands outside q = 1.

  3. Visco-Resistive MHD Modeling Benchmark of Forced Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Beidler, M. T.; Hegna, C. C.; Sovinec, C. R.; Callen, J. D.; Ferraro, N. M.

    2016-10-01

    The presence of externally-applied 3D magnetic fields can affect important phenomena in tokamaks, including mode locking, disruptions, and edge localized modes. External fields penetrate into the plasma and can lead to forced magnetic reconnection (FMR), and hence magnetic islands, on resonant surfaces if the local plasma rotation relative to the external field is slow. Preliminary visco-resistive MHD simulations of FMR in a slab geometry are consistent with theory. Specifically, linear simulations exhibit proper scaling of the penetrated field with resistivity, viscosity, and flow, and nonlinear simulations exhibit a bifurcation from a flow-screened to a field-penetrated, magnetic island state as the external field is increased, due to the 3D electromagnetic force. These results will be compared to simulations of FMR in a circular cross-section, cylindrical geometry by way of a benchmark between the NIMROD and M3D-C1 extended-MHD codes. Because neither this geometry nor the MHD model has the physics of poloidal flow damping, the theory of will be expanded to include poloidal flow effects. The resulting theory will be tested with linear and nonlinear simulations that vary the resistivity, viscosity, flow, and external field. Supported by OFES DoE Grants DE-FG02-92ER54139, DE-FG02-86ER53218, DE-AC02-09CH11466, and the SciDAC Center for Extended MHD Modeling.

  4. Magnus: A New Resistive MHD Code with Heat Flow Terms

    NASA Astrophysics Data System (ADS)

    Navarro, Anamaría; Lora-Clavijo, F. D.; González, Guillermo A.

    2017-07-01

    We present a new magnetohydrodynamic (MHD) code for the simulation of wave propagation in the solar atmosphere, under the effects of electrical resistivity—but not dominant—and heat transference in a uniform 3D grid. The code is based on the finite-volume method combined with the HLLE and HLLC approximate Riemann solvers, which use different slope limiters like MINMOD, MC, and WENO5. In order to control the growth of the divergence of the magnetic field, due to numerical errors, we apply the Flux Constrained Transport method, which is described in detail to understand how the resistive terms are included in the algorithm. In our results, it is verified that this method preserves the divergence of the magnetic fields within the machine round-off error (˜ 1× {10}-12). For the validation of the accuracy and efficiency of the schemes implemented in the code, we present some numerical tests in 1D and 2D for the ideal MHD. Later, we show one test for the resistivity in a magnetic reconnection process and one for the thermal conduction, where the temperature is advected by the magnetic field lines. Moreover, we display two numerical problems associated with the MHD wave propagation. The first one corresponds to a 3D evolution of a vertical velocity pulse at the photosphere-transition-corona region, while the second one consists of a 2D simulation of a transverse velocity pulse in a coronal loop.

  5. MHD simulations with resistive wall and magnetic separatrix

    NASA Astrophysics Data System (ADS)

    Strauss, H. R.; Pletzer, A.; Park, W.; Jardin, S.; Breslau, J.; Sugiyama, L.

    2004-12-01

    A number of problems in resistive MHD magnetic fusion simulations describe plasmas with three regions: the core, the halo region, and the resistive boundary. Treating these problems requires maintenance of an adequate resistivity contrast between the core and halo. This can be helped by the presence of a magnetic separatrix, which in any case is required for reasons of realistic modeling. An appropriate mesh generation capability is also needed to include the halo region when a separatrix is present. Finally a resistive wall boundary condition is required, to allow both two dimensional and three dimensional magnetic perturbations to penetrate the wall. Preliminary work is presented on halo current simulations in ITER. The first step is the study of VDE (vertical displacement event) instabilities. The growth rate is consistent with scaling inversely proportional to the resistive wall penetration time. The simulations have resistivity proportional to the -3/2 power of the temperature. Simulations have been done with resistivity contrast between the plasma core and wall of 1000 times, to model the vacuum region between the core and resistive shell. Some 3D simulations are shown of disruptions competing with VDEs. Toroidal peaking factors are up to about 3.

  6. Kinetic effects of energetic particles on resistive MHD stability.

    PubMed

    Takahashi, R; Brennan, D P; Kim, C C

    2009-04-03

    We show that the kinetic effects of energetic particles can play a crucial role in the stability of the m/n=2/1 tearing mode in tokamaks (e.g., JET, JT-60U, and DIII-D), where the fraction of energetic particle beta(frac) is high. Using model equilibria based on DIII-D experimental reconstructions, the nonideal MHD linear stability of cases unstable to the 2/1 mode is investigated including a deltaf particle-in-cell model for the energetic particles coupled to the nonlinear 3D resistive MHD code NIMROD [C. C. Kim et al., Phys. Plasmas 15, 072507 (2008)10.1063/1.2949704]. It is observed that energetic particles have significant damping and stabilizing effects at experimentally relevant beta, beta(frac), and S, and excite a real frequency of the 2/1 mode. Extrapolation of the results is discussed for implications to JET and ITER, where the effects are projected to be significant.

  7. MHD modeling of magnetotail instability for localized resistivity

    NASA Technical Reports Server (NTRS)

    Hesse, Michael; Birn, Joachim

    1994-01-01

    We present results of a three-dimensional magnetohydrodynamic (MHD) simulation of magnetotail evolution initiated by a sudden occurrence or increase of spatially localized resistivity as the major expected concequence of some localized microinstability. Because of the absence of a quantitative model, possible variations of resistivity levels with current density, or the reduction thereof, are not incorporated in the present investigation. The emphasis of the study is on an investigation of the changes to the overall evolution brought about by this localization, in particular, on the disruption and diversion of the cross-tail current and the nonlinear evolution of the magnetotail instability. The immediate consequences of the occurrence of the localized resistance and the resulting electric field are a reduction and diversion of the electric current around the region of high resistivity, associated with an increase of B(sub z) ('dipolarization') at the earthward edge and a decrease of B(sub z) at the tailward edge of this region. These effects, however, are localized and do not involve a reduction of the total cross-tail current and hence do not lead to the global development of a 'substorm current wedge,' which includes not only the reduction of the cross-tail current but also the buildup of a global field-aligned current system of 'regional 1' type (toward the Earth on the dawnside and away on the duskside of the tail). Such signatures develop at a later time, as consequences of a three-dimensional tearing instability, which is triggered by the occurrence of the resistivity. These features are found in combination with plasmoid formation and ejection, quite similar to results of earlier simulations with uniform resistivity. Differences are found in the timescale of the evolution, which tends to be shorter for localized resistivity, and in the propagation of the dipolarization effects in the equatorial plane. Whereas for uniform resistivity the temporal increase in

  8. Towards a Scalable Fully-Implicit Fully-coupled Resistive MHD Formulation with Stabilized FE Methods

    SciTech Connect

    Shadid, J N; Pawlowski, R P; Banks, J W; Chacon, L; Lin, P T; Tuminaro, R S

    2009-06-03

    This paper presents an initial study that is intended to explore the development of a scalable fully-implicit stabilized unstructured finite element (FE) capability for low-Mach-number resistive MHD. The discussion considers the development of the stabilized FE formulation and the underlying fully-coupled preconditioned Newton-Krylov nonlinear iterative solver. To enable robust, scalable and efficient solution of the large-scale sparse linear systems generated by the Newton linearization, fully-coupled algebraic multilevel preconditioners are employed. Verification results demonstrate the expected order-of-acuracy for the stabilized FE discretization of a 2D vector potential form for the steady and transient solution of the resistive MHD system. In addition, this study puts forth a set of challenging prototype problems that include the solution of an MHD Faraday conduction pump, a hydromagnetic Rayleigh-Bernard linear stability calculation, and a magnetic island coalescence problem. Initial results that explore the scaling of the solution methods are presented on up to 4096 processors for problems with up to 64M unknowns on a CrayXT3/4. Additionally, a large-scale proof-of-capability calculation for 1 billion unknowns for the MHD Faraday pump problem on 24,000 cores is presented.

  9. 3D MHD VDE and disruptions simulations of tokamaks plasmas including some ITER scenarios

    NASA Astrophysics Data System (ADS)

    Paccagnella, R.; Strauss, H. R.; Breslau, J.

    2009-03-01

    Tokamaks vertical displacement events (VDEs) and disruptions simulations in toroidal geometry by means of a single fluid visco-resistive magneto-hydro-dynamic (MHD) model are presented in this paper. The plasma model is completed with the presence of a 2D wall with finite resistivity which allows the study of the relatively slowly growing magnetic perturbation, the resistive wall mode (RWM), which is, in this paper, the main drive of the disruption evolution. Amplitudes and asymmetries of the halo currents pattern at the wall are also calculated and comparisons with tokamak experimental databases and predictions for ITER are given.

  10. Flow stabilization of the ideal MHD resistive wall mode^1

    NASA Astrophysics Data System (ADS)

    Smith, S. P.; Jardin, S. C.; Freidberg, J. P.; Guazzotto, L.

    2009-05-01

    We demonstrate for the first time in a numerical calculation that for a typical circular cylindrical equilibrium, the ideal MHD resistive wall mode (RWM) can be completely stabilized by bulk equilibrium plasma flow, V, for a window of wall locations without introducing additional dissipation into the system. The stabilization is due to a resonance between the RWM and the Doppler shifted ideal MHD sound continuum. Our numerical approach introduces^2 u=φξ+ iV .∇ξ and the perturbed wall current^3 as variables, such that the eigenvalue, φ, only appears linearly in the linearized stability equations, which allows for the use of standard eigenvalue solvers. The wall current is related to the plasma displacement at the boundary by a Green's function. With the introduction of the resistive wall, we find that it is essential that the finite element grid be highly localized around the resonance radius where the parallel displacement, ξ, becomes singular. We present numerical convergence studies demonstrating that this singular behavior can be approached in a limiting sense. We also report on progress toward extending this calculation to an axisymmetric toroidal geometry. ^1Work supported by a DOE FES fellowship through ORISE and ORAU. ^2L.Guazzotto, J.P Freidberg, and R. Betti, Phys.Plasmas 15, 072503 (2008). ^3S.P. Smith and S. C. Jardin, Phys. Plasmas 15, 080701 (2008).

  11. A Gas-kinetic Scheme for the Two-Fluid MHD Equations with Resistivity

    NASA Astrophysics Data System (ADS)

    Anderson, Steven; Girimaji, Sharath; da Silva, Eduardo; Siebert, Diogo; Salazar, Juan

    2016-11-01

    The two-fluid MHD equations are a simplified model of plasma flow wherein a mixture of two species (electrons and ions) is considered. In this model, unlike single-fluid MHD, quasi-neutrality is not enforced, Ohm's Law is not used, and the fluids are not in thermal equilibrium - thus both fluids assume their own density, velocity, and temperature. Here we present a numerical scheme to solve the two-fluid MHD equations based on an extension of the gas-kinetic method. In contrast to previous implementations of the gas-kinetic scheme for MHD, the solution of the non-equilibrium distribution function for each gas at the cell interface is extended to include the effect of the electromagnetic forces as well as the inter-species collisions (resistivity). Closure of the fluid equations with the electromagnetic fields is obtained through Maxwell's equations, and physically correct divergences are enforced via correction potentials. Maxwell's equations are integrated via a simple Lax-Friedrichs type flux-splitting. To separate integration of the source and flux terms in the governing equations we use Strang splitting. Some numerical results are presented to demonstrate accuracy of the scheme and we discuss advantages and potential applications of the scheme. This research was supported by National Science Foundation Grant Number DGE-1252521 and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) of Brazil.

  12. The ideal tearing mode: theory and resistive MHD simulations

    NASA Astrophysics Data System (ADS)

    Del Zanna, L.; Landi, S.; Papini, E.; Pucci, F.; Velli, M.

    2016-05-01

    Classical MHD reconnection theories, both the stationary Sweet-Parker model and the tearing instability, are known to provide rates which are too slow to explain the observations. However, a recent analysis has shown that there exists a critical threshold on current sheet's thickness, namely a/L ∼ S -1/3, beyond which the tearing modes evolve on fast macroscopic Alfvénic timescales, provided the Lunquist number S is high enough, as invariably found in solar and astrophysical plasmas. Therefore, the classical Sweet-Parker scenario, for which the diffusive region scales as a/L ∼ S -1/2 and thus can be up to ∼ 100 times thinner than the critical value, is likely to be never realized in nature, as the current sheet itself disrupts in the elongation process. We present here two-dimensional, compressible, resistive MHD simulations, with S ranging from 105 to 107, that fully confirm the linear analysis. Moreover, we show that a secondary plasmoid instability always occurs when the same critical scaling is reached on the local, smaller scale, leading to a cascading explosive process, reminiscent of the flaring activity.

  13. Viscous, resistive MHD stability computed by spectral techniques

    NASA Technical Reports Server (NTRS)

    Dahlburg, R. B.; Zang, T. A.; Montgomery, D.; Hussaini, M. Y.

    1983-01-01

    Expansions in Chebyshev polynomials are used to study the linear stability of one dimensional magnetohydrodynamic (MHD) quasi-equilibria, in the presence of finite resistivity and viscosity. The method is modeled on the one used by Orszag in accurate computation of solutions of the Orr-Sommerfeld equation. Two Reynolds like numbers involving Alfven speeds, length scales, kinematic viscosity, and magnetic diffusivity govern the stability boundaries, which are determined by the geometric mean of the two Reynolds like numbers. Marginal stability curves, growth rates versus Reynolds like numbers, and growth rates versus parallel wave numbers are exhibited. A numerical result which appears general is that instability was found to be associated with inflection points in the current profile, though no general analytical proof has emerged. It is possible that nonlinear subcritical three dimensional instabilities may exist, similar to those in Poiseuille and Couette flow.

  14. Role of Loss of Equilibrium and Magnetic Reconnection in Coronal Eruptions: Resistive and Hall MHD simulations

    NASA Astrophysics Data System (ADS)

    Yang, H.; Bhattacharjee, A.; Forbes, T. G.

    2008-12-01

    It has long been suggested that eruptive phenomena such as coronal mass ejections, prominence eruptions, and large flares might be caused by a loss of equilibrium in a coronal flux rope (Van Tend and Kuperus, 1978). Forbes et al. (1994) developed an analytical two-dimensional model in which eruptions occur due to a catastrophic loss of equilibrium and relaxation to a lower-energy state containing a thin current sheet. Magnetic reconnection then intervenes dynamically, leading to the release of magnetic energy and expulsion of a plasmoid. We have carried out high-Lundquist-number simulations to test the loss-of equilibrium mechanism, and demonstrated that it does indeed occur in the quasi-ideal limit. We have studied the subsequent dynamical evolution of the system in resistive and Hall MHD models for single as well as multiple arcades. The typical parallel electric fields are super-Dreicer, which makes it necessary to include collisionless effects via a generalized Ohm's law. It is shown that the nature of the local dissipation mechanism has a significant effect on the global geometry and dynamics of the magnetic configuration. The presence of Hall currents is shown to alter the length of the current sheet and the jets emerging from the reconnection site, directed towards the chromosphere. Furthermore, Hall MHD effects break certain symmetries of resistive MHD dynamics, and we explore their observational consequences.

  15. Scalable implicit incompressible resistive MHD with stabilized FE and fully-coupled Newton–Krylov-AMG

    SciTech Connect

    Shadid, J. N.; Pawlowski, R. P.; Cyr, E. C.; Tuminaro, R. S.; Chacon, L.; Weber, P. D.

    2016-02-10

    Here, we discuss that the computational solution of the governing balance equations for mass, momentum, heat transfer and magnetic induction for resistive magnetohydrodynamics (MHD) systems can be extremely challenging. These difficulties arise from both the strong nonlinear, nonsymmetric coupling of fluid and electromagnetic phenomena, as well as the significant range of time- and length-scales that the interactions of these physical mechanisms produce. This paper explores the development of a scalable, fully-implicit stabilized unstructured finite element (FE) capability for 3D incompressible resistive MHD. The discussion considers the development of a stabilized FE formulation in context of the variational multiscale (VMS) method, and describes the scalable implicit time integration and direct-to-steady-state solution capability. The nonlinear solver strategy employs Newton–Krylov methods, which are preconditioned using fully-coupled algebraic multilevel preconditioners. These preconditioners are shown to enable a robust, scalable and efficient solution approach for the large-scale sparse linear systems generated by the Newton linearization. Verification results demonstrate the expected order-of-accuracy for the stabilized FE discretization. The approach is tested on a variety of prototype problems, that include MHD duct flows, an unstable hydromagnetic Kelvin–Helmholtz shear layer, and a 3D island coalescence problem used to model magnetic reconnection. Initial results that explore the scaling of the solution methods are also presented on up to 128K processors for problems with up to 1.8B unknowns on a CrayXK7.

  16. Performance analysis of the MHD-steam combined cycle, including the influence of cost

    SciTech Connect

    Berry, G. F.; Dennis, C. B.

    1980-08-01

    The MHD Systems group of the ANL Engineering Division is conducting overall system studies, utilizing the computer simulation code that has been developed at ANL. This analytical investigation is exploring a range of possible performance variables, in order to determine the sensitivity of a specific plant design to variation in key system parameters and, ultimately, to establish probable system performance limits. The comprehensive computer code that has been developed for this task will analyze and simulate an MHD power plant for any number of different configurations, and will hold constraints automatically while conducting either sensitivity studies or optimization. A summary of a sensitivity analysis conducted for a combined cycle, MHD-steam power plant is presented. The influence of several of the more important systems parameters were investigated in a systematic fashion, and the results are presented in graphical form. The report is divided into four sections. Following the introduction, the second section describes in detail the results of a validation study conducted to insure that the code is functioning correctly. The third section includes a description of the ANL cost algorithm and a detailed comparison between the ANL cost results and published OCMHD cost information. it is further demonstrated in this section that good agreement is obtained for the calculated cost of electricity. The fourth section is a sensitivity study and optimization for a specific OCMHD configuration over several key plant parameters.

  17. Resistive MHD studies of high-. beta. -tokamak plasmas

    SciTech Connect

    Lynch, V.E.; Carreras, B.A.; Hicks, H.R.; Holmes, J.A.; Garcia, L.

    1981-01-01

    Numerical calculations have been performed to study the MHD activity in high-..beta.. tokamaks such as ISX-B. These initial value calculations built on earlier low ..beta.. techniques, but the ..beta.. effects create several new numerical issues. These issues are discussed and resolved. In addition to time-stepping modules, our system of computer codes includes equilibrium solvers (used to provide an initial condition) and output modules, such as a magnetic field line follower and an X-ray diagnostic code. The transition from current driven modes at low ..beta.. to predominantly pressure driven modes at high ..beta.. is described. The nonlinear studies yield X-ray emissivity plots which are compared with experiment.

  18. A Numerical Study of Resistivity and Hall Effects for a Compressible MHD Model

    NASA Technical Reports Server (NTRS)

    Yee, H. C.; Sjogreen, B.

    2005-01-01

    The effect of resistive, Hall, and viscous terms on the flow structure compared with compressible ideal MHD is studied numerically for a one-fluid non-ideal MHD model. The goal of the present study is to shed some light on the emerging area of non-ideal MHD modeling and simulation. Numerical experiments are performed on a hypersonic blunt body flow with future application to plasma aerodynamics flow control in reentry vehicles. Numerical experiments are also performed on a magnetized time-developing mixing layer with possible application to magnetic/turbulence mixing.

  19. Scalable implicit incompressible resistive MHD with stabilized FE and fully-coupled Newton–Krylov-AMG

    DOE PAGES

    Shadid, J. N.; Pawlowski, R. P.; Cyr, E. C.; ...

    2016-02-10

    Here, we discuss that the computational solution of the governing balance equations for mass, momentum, heat transfer and magnetic induction for resistive magnetohydrodynamics (MHD) systems can be extremely challenging. These difficulties arise from both the strong nonlinear, nonsymmetric coupling of fluid and electromagnetic phenomena, as well as the significant range of time- and length-scales that the interactions of these physical mechanisms produce. This paper explores the development of a scalable, fully-implicit stabilized unstructured finite element (FE) capability for 3D incompressible resistive MHD. The discussion considers the development of a stabilized FE formulation in context of the variational multiscale (VMS) method,more » and describes the scalable implicit time integration and direct-to-steady-state solution capability. The nonlinear solver strategy employs Newton–Krylov methods, which are preconditioned using fully-coupled algebraic multilevel preconditioners. These preconditioners are shown to enable a robust, scalable and efficient solution approach for the large-scale sparse linear systems generated by the Newton linearization. Verification results demonstrate the expected order-of-accuracy for the stabilized FE discretization. The approach is tested on a variety of prototype problems, that include MHD duct flows, an unstable hydromagnetic Kelvin–Helmholtz shear layer, and a 3D island coalescence problem used to model magnetic reconnection. Initial results that explore the scaling of the solution methods are also presented on up to 128K processors for problems with up to 1.8B unknowns on a CrayXK7.« less

  20. The effects of differential flow between rational surfaces on toroidal resistive MHD modes

    NASA Astrophysics Data System (ADS)

    Brennan, Dylan; Halfmoon, Michael; Rhodes, Dov; Cole, Andrew; Okabayashi, Michio; Paz-Soldan, Carlos; Finn, John

    2016-10-01

    Differential flow between resonant surfaces can strongly affect the coupling and penetration of resonant components of resistive modes, and yet this mechanism is not yet fully understood. This study focuses on the evolution of tearing instabilities and the penetration of imposed resonant magnetic perturbations (RMPs) in tokamak configurations relevant to DIII-D and ITER, including equilibrium flow shear. It has been observed on DIII-D that the onset of tearing instabilities leading to disruption is often coincident with a loss of differential rotation between a higher m/n tearing surface (normally the 4/3 or 3/2) and a lower m/n tearing surface (normally the 2/1). Imposing RMPs can strongly affect this coupling and the torques between the modes. We apply the nonlinear 3-D resistive magnetohydrodynamic (MHD) code NIMROD to study the mechanisms by which these couplings occur. Reduced MHD analyses are applied to study the effects of differential flow between resonant surfaces in the simulations. Interaction between resonant modes can cause significant energy transfer between them, effectively stabilizing one mode while the other grows. The flow mitigates this transfer, but also affects the individual modes. The combination of these effects determines the nonlinear outcome. Supported by US DOE Grants DE-SC0014005 and DE-SC0014119.

  1. Coalescence of magnetic islands in the low-resistivity, Hall-MHD regime.

    PubMed

    Knoll, D A; Chacón, L

    2006-04-07

    The coalescence of magnetic islands in the low-resistivity eta, Hall-MHD regime is studied. The interaction between the ion inertial length d(i) and the dynamically evolving current sheet scale length deltaJ is established. Initially, d(i) < deltaJ. If eta is such that deltaJ dynamically thins down to d(i) prior to the well-known sloshing phenomena, then sloshing is avoided. This results in eta independent peak reconnection rates. However, if d(i) is small enough that deltaJ cannot be thinned down to this scale prior to sloshing, then sloshing proceeds as in the resistive MHD model.

  2. 2--D Resistive MHD Simulations of Merging Co-- and Counter--Helicity Spheromaks

    NASA Astrophysics Data System (ADS)

    Carter, T. A.; Jardin, S. C.

    1997-11-01

    Studies of the global equilibrium properties of merging spheromaks as well as of the local properties of the reconnection boundary layer in the MHD limit will be presented. The Princeton Tokamak Simulation Code (TSC)(S.C. Jardin, et. al., J. Comp. Phys. 66) (1986) 481, a free--boundary, axisymmetric resistive MHD code, is modified to resolve the two spatial scales of the merging spheromak problem, the equilibrium scale and the boundary layer, and to include convective terms in the coded set of scalar momentum equations. The simulations reported here are performed with parameters T ~ 15 eV, ne ~ 10^14 cm-3, Bz ~ 2 kG. We present comparisons of our simulation results with results from recent analytic(R. Kulsrud, D. Uzdensky, personal communication) and experimental work(M. Yamada, et. al., Phys. Rev. Lett. 78) (1997) 3117 and Y. Ono, et. al., Phys. Rev. Lett. 76 (1996) 3328. In particular we emphasize merging rates for co-- and counter--helicity merging, boundary layer geometry, scaling of merging rate with dimensionless parameters, and formation of spheromak and Field Reversed Configuration (FRC) plasmas as a result of co-- and counter--helicity merging.

  3. Proceedings of the workshop on nonlinear MHD and extended MHD

    SciTech Connect

    1998-12-01

    Nonlinear MHD simulations have proven their value in interpreting experimental results over the years. As magnetic fusion experiments reach higher performance regimes, more sophisticated experimental diagnostics coupled with ever expanding computer capabilities have increased both the need for and the feasibility of nonlinear global simulations using models more realistic than regular ideal and resistive MHD. Such extended-MHD nonlinear simulations have already begun to produce useful results. These studies are expected to lead to ever more comprehensive simulation models in the future and to play a vital role in fully understanding fusion plasmas. Topics include the following: (1) current state of nonlinear MHD and extended-MHD simulations; (2) comparisons to experimental data; (3) discussions between experimentalists and theorists; (4) /equations for extended-MHD models, kinetic-based closures; and (5) paths toward more comprehensive simulation models, etc. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.

  4. Non-linear MHD Simulation of ELMs including Pellet Triggered ones for KSTAR tokamak

    NASA Astrophysics Data System (ADS)

    Han, Hyunsun; Park, G.; Strauss, H.; Kim, J. Y.

    2011-10-01

    Three-dimensional non-linear MHD simulations have been conducted to investigate the qualitative characteristics of ELM(Edge Localized Mode)s including pellet induced ones using the M3D code. A linearized velocity perturbation of initial equilibrium is employed to trigger the ELM instability for the simulation of natural ELM, while a density blob, which represents the ionized pellet ablation and is located within the edge pedestal, is adopted in an adiabatic condition for that of pellet induced one. The initial equilibrium is constructed based on a H-mode plasma of KSTAR(Korea Superconducting Tokamak Advanced Research) device. It is found that characteristics of natural ELM simulation are in qualitative agreement with the experimental observations including that density perturbation is much larger than temperature one during ELM instability. Regarding the pellet induced ELM, it is observed that the locally increased pressure due to the fast parallel heat conduction compared to the spread of density perturbation triggers the peeling-ballooning instability resulting in ELM-like relaxation. Detailed results will be presented in the discussion of underlying mechanism and application to KSTAR tokamak.

  5. Non-linear Simulations of MHD Instabilities in Tokamaks Including Eddy Current Effects and Perspectives for the Extension to Halo Currents

    NASA Astrophysics Data System (ADS)

    Hoelzl, M.; Huijsmans, G. T. A.; Merkel, P.; Atanasiu, C.; Lackner, K.; Nardon, E.; Aleynikova, K.; Liu, F.; Strumberger, E.; McAdams, R.; Chapman, I.; Fil, A.

    2014-11-01

    The dynamics of large scale plasma instabilities can be strongly influenced by the mutual interaction with currents flowing in conducting vessel structures. Especially eddy currents caused by time-varying magnetic perturbations and halo currents flowing directly from the plasma into the walls are important. The relevance of a resistive wall model is directly evident for Resistive Wall Modes (RWMs) or Vertical Displacement Events (VDEs). However, also the linear and non-linear properties of most other large-scale instabilities may be influenced significantly by the interaction with currents in conducting structures near the plasma. The understanding of halo currents arising during disruptions and VDEs, which are a serious concern for ITER as they may lead to strong asymmetric forces on vessel structures, could also benefit strongly from these non-linear modeling capabilities. Modeling the plasma dynamics and its interaction with wall currents requires solving the magneto-hydrodynamic (MHD) equations in realistic toroidal X-point geometry consistently coupled with a model for the vacuum region and the resistive conducting structures. With this in mind, the non-linear finite element MHD code JOREK [1, 2] has been coupled [3] with the resistive wall code STARWALL [4], which allows us to include the effects of eddy currents in 3D conducting structures in non-linear MHD simulations. This article summarizes the capabilities of the coupled JOREK-STARWALL system and presents benchmark results as well as first applications to non-linear simulations of RWMs, VDEs, disruptions triggered by massive gas injection, and Quiescent H-Mode. As an outlook, the perspectives for extending the model to halo currents are described.

  6. A Numerical Approach to Solving the Hall MHD Equations Including Diamagnetic Drift (Preprint)

    DTIC Science & Technology

    2008-02-19

    References [1] J. Birn and et al. Geospace environmental modeling (gem) magnetic reconnection challenge. Journal of Geophysical Research, 106(A3):3715–3719...equations. Journal of Computational Physics, 179:495–538, 2002. [21] A. Otto. Geospace environment modeling (gem) magnetic reconnection challenge: Mhd

  7. Computational modeling of neoclassical and resistive MHD tearing modes in tokamaks

    SciTech Connect

    Gianakon, Thomas A.

    1996-02-01

    Numerical studies of the linear and nonlinear evolution of magnetic tearing type modes in three-dimensional toroidal geometry are presented. In addition to traditional resistive MHD effects, where the parameter Δ' determines the stability properties, neoclassical effects have been included for the first time in such models. The inclusion of neoclassical physics introduces and additional free-energy source for the nonlinear formation of magnetic islands through the effects of a bootstrap current in Ohm`s law. The neoclassical tearing mode is demonstrated to be destabilized in plasmas which are otherwise Δ' stable, albeit once an island width threshold is exceeded. The simulations are based on a set of neoclassical reduced magnetohydrodynamic (MHD) equations in three-dimensional toroidal geometry derived from the two-fluid equations in the limit of small inverse aspect ratio ε and low plasma pressure β with neoclassical closures for the viscous force ∇• $\\vec{π}$. The poloidal magnetic flux Ψ, the toroidal vorticity ωζ, and the plasma pressure p are time advanced using the parallel projection of Ohm`s law, the toroidal projection of the curl of the momentum equation, and a pressure evolution equation with anisotropic pressure transport parallel to and across magnetic field lines. The equations are implemented in an initial value code which Fourier decomposes equilibrium and perturbation quantities in the poloidal and toroidal directions, and finite differences them radially based on a equilibrium straight magnetic field line representation. An implicit algorithm is used to advance the linear terms; the nonlinear terms are advanced explicitly. The simulations are benchmarked linearly and nonlinearly against single and multiple helicity Δ' tearing modes in toroidal geometry in the absence of neo-classical effects.

  8. On the Measurements of Numerical Viscosity and Resistivity in Eulerian MHD Codes

    NASA Astrophysics Data System (ADS)

    Rembiasz, Tomasz; Obergaulinger, Martin; Cerdá-Durán, Pablo; Aloy, Miguel-Ángel; Müller, Ewald

    2017-06-01

    We propose a simple ansatz for estimating the value of the numerical resistivity and the numerical viscosity of any Eulerian MHD code. We test this ansatz with the help of simulations of the propagation of (magneto)sonic waves, Alfvén waves, and the tearing mode (TM) instability using the MHD code Aenus. By comparing the simulation results with analytical solutions of the resistive-viscous MHD equations and an empirical ansatz for the growth rate of TMs, we measure the numerical viscosity and resistivity of Aenus. The comparison shows that the fast magnetosonic speed and wavelength are the characteristic velocity and length, respectively, of the aforementioned (relatively simple) systems. We also determine the dependence of the numerical viscosity and resistivity on the time integration method, the spatial reconstruction scheme and (to a lesser extent) the Riemann solver employed in the simulations. From the measured results, we infer the numerical resolution (as a function of the spatial reconstruction method) required to properly resolve the growth and saturation level of the magnetic field amplified by the magnetorotational instability in the post-collapsed core of massive stars. Our results show that it is most advantageous to resort to ultra-high-order methods (e.g., the ninth-order monotonicity-preserving method) to tackle this problem properly, in particular, in three-dimensional simulations.

  9. Impact of resistive MHD plasma response on perturbation field sidebands

    DOE PAGES

    Orlov, D. M.; Evans, T. E.; Moyer, R. A.; ...

    2016-06-03

    Here, single fluid linear simulations of a KSTAR RMP ELM suppressed discharge with the M3D-C1 resistive magnetohydrodynamic code have been performed for the first time. The simulations show that the application of the n = 1 perturbation using the KSTAR in-vessel control coils (IVCC), which apply modest levels of n = 3 sidebands (~20% of the n = 1), leads to levels of n = 3 sideband that are comparable to the n = 1 when plasma response is included. This is due to the reduced level of screening of the rational-surface-resonant n = 3 component relative to the rational-surface-resonantmore » n = 1 component. The n = 3 sidebands could play a similar role in ELM suppression on KSTAR as the toroidal sidebands (n = 1, 2, 4) in DIII-D n = 3 ELM suppression with missing I-coil segments. This result may help to explain the uniqueness of ELM suppression with n = 1 perturbations in KSTAR since the effective perturbation is a mixed n = 1/n = 3 perturbation similar to n = 3 ELM suppression in DIII-D.« less

  10. Impact of resistive MHD plasma response on perturbation field sidebands

    SciTech Connect

    Orlov, D. M.; Evans, T. E.; Moyer, R. A.; Lyons, B. C.; Ferraro, N. M.; Park, G-Y

    2016-06-03

    Here, single fluid linear simulations of a KSTAR RMP ELM suppressed discharge with the M3D-C1 resistive magnetohydrodynamic code have been performed for the first time. The simulations show that the application of the n = 1 perturbation using the KSTAR in-vessel control coils (IVCC), which apply modest levels of n = 3 sidebands (~20% of the n = 1), leads to levels of n = 3 sideband that are comparable to the n = 1 when plasma response is included. This is due to the reduced level of screening of the rational-surface-resonant n = 3 component relative to the rational-surface-resonant n = 1 component. The n = 3 sidebands could play a similar role in ELM suppression on KSTAR as the toroidal sidebands (n = 1, 2, 4) in DIII-D n = 3 ELM suppression with missing I-coil segments. This result may help to explain the uniqueness of ELM suppression with n = 1 perturbations in KSTAR since the effective perturbation is a mixed n = 1/n = 3 perturbation similar to n = 3 ELM suppression in DIII-D.

  11. Impact of resistive MHD plasma response on perturbation field sidebands

    NASA Astrophysics Data System (ADS)

    Orlov, D. M.; Evans, T. E.; Moyer, R. A.; Lyons, B. C.; Ferraro, N. M.; Park, G.-Y.

    2016-07-01

    Single fluid linear simulations of a KSTAR RMP ELM suppressed discharge with the M3D-C1 resistive magnetohydrodynamic code have been performed for the first time. The simulations show that the application of the n  =  1 perturbation using the KSTAR in-vessel control coils (IVCC), which apply modest levels of n  =  3 sidebands (~20% of the n  =  1), leads to levels of n  =  3 sideband that are comparable to the n  =  1 when plasma response is included. This is due to the reduced level of screening of the rational-surface-resonant n  =  3 component relative to the rational-surface-resonant n  =  1 component. The n  =  3 sidebands could play a similar role in ELM suppression on KSTAR as the toroidal sidebands (n  =  1, 2, 4) in DIII-D n  =  3 ELM suppression with missing I-coil segments (Paz Soldan et al 2014 Nucl. Fusion 54 073013). This result may help to explain the uniqueness of ELM suppression with n  =  1 perturbations in KSTAR since the effective perturbation is a mixed n  =  1/n  =  3 perturbation similar to n  =  3 ELM suppression in DIII-D.

  12. Linear Analysis of the m=0 Instability for a Visco-resistive Hall MHD Plasma

    SciTech Connect

    Oliver, B.V.; Genoni, T.C.; Mehlhorn, T.A.

    2006-01-05

    We present a comprehensive analysis of the linear dispersion relation for the axisymmetric (m=0) compressible interchange instability of Bennett equilibria in a visco-resistive, Hall MHD plasma. The full anisotropic stress tensor with Braginskii viscous coefficients is considered. The eigenvalues are obtained numerically. For small axial mode number, Hall currents enhance the growth rates, whereas in the limit of high mode number the growth rates are suppressed, eventually resulting in wave cutoff, even in the ideal limit. For the visco-resistive plasma the unstable spectra are weakly dependent on the off-diagonal elements of the stress tensor.

  13. Ideal and resistive MHD stability of one-dimensional tokamak equilibria

    SciTech Connect

    Chance, M.S.; Furth, H.P.; Glasser, A.H.; Selberg, H.

    1981-07-01

    The MHD equilibrium and stability of a vertically elongated tokamak configuration are analyzed in the one-dimensional limit corresponding to infinite elongation. Stability against all ideal MHD modes can be obtained for beta-values arbitrarily close to unity. In the finite-resistivity stability analysis, axisymmetric (m = 0) tearing modes, centered on the null trace of the poloidal field, can be stabilized by a loosely fitting conducting shell. The presence of the toroidal field component, however, introduces the possibility of nonsymmetric tearing modes (m not equal to 0), centered away from the null trace. These modes can be stabilized only by a more tightly-fitting shell, plus reliance on finite-pressure effects on the small-major-radius side of the plasma profile. Under these conditions, stable configurations with peak beta values approaching unity are readily found.

  14. A Coupled MHD and Thermal Model Including Electrostatic Sheath for Magnetoplasmadynamic Thruster Simulation

    NASA Astrophysics Data System (ADS)

    Kawasaki, Akira; Kubota, Kenichi; Funaki, Ikkoh; Okuno, Yoshihiro

    2016-09-01

    Steady-state and self-field magnetoplasmadynamic (MPD) thruster, which utilizes high-intensity direct-current (DC) discharge, is one of the prospective candidates of future high-power electric propulsion devices. In order to accurately assess the thrust performance and the electrode temperature, input electric power and wall heat flux must correctly be evaluated where electrostatic sheaths formed in close proximity of the electrodes affect these quantities. Conventional model simulates only plasma flows occurring in MPD thrusters with the absence of electrostatic sheath consideration. Therefore, this study extends the conventional model to a coupled magnetohydrodynamic (MHD) and thermal model by incorporating the phenomena relevant to the electrostatic sheaths. The sheaths are implemented as boundary condition of the MHD model on the walls. This model simulated the operation of the 100-kW-class thruster at discharge current ranging from 6 to 10 kA with argon propellant. The extended model reproduced the discharge voltages and wall heat load which are consistent with past experimental results. In addition, the simulation results indicated that cathode sheath voltages account for approximately 5-7 V subject to approximately 20 V of discharge voltages applied between the electrodes. This work was supported by JSPS KAKENHI Grant Numbers 26289328 and 15J10821.

  15. Evolution of generalized two-dimensional magnetotail equilibria in ideal and resistive MHD

    NASA Astrophysics Data System (ADS)

    Merkin, V. G.; Sitnov, M. I.; Lyon, J. G.

    2015-03-01

    We present results of two-dimensional (2-D) magnetohydrodynamic (MHD) simulations of the terrestrial magnetotail. A regional adaptation of the Lyon-Fedder-Mobarry global MHD model is used. As initial conditions, we employ a class of asymptotic magnetotail equilibria with and without an accumulation of magnetic flux at the tailward end (a Bz hump). The former have been recently shown by full particle simulations to be unstable to a kinetic mode with formal properties of ion tearing. Thus, our goal here is to investigate the evolution of the same equilibria in the MHD approximation and assist in the physical interpretation of the kinetic simulations. This is additionally motivated by the energy principle considerations which suggest that if the system is unstable kinetically, it may also be unstable ideally. To seek dynamical MHD regimes similar to those observed in kinetic simulations, we implement two sets of boundary conditions (velocity balanced, VB, and momentum balanced, MB), one allowing plasma flows through the boundaries and the other inhibiting such flows. The use of more reflecting MB boundary conditions results in suppression of any significant dynamics, and we see no substantial changes beyond initial equilibrium relaxation. On the other hand, VB boundary conditions allow a more efficient relaxation of initial equilibrium and absorb subsequently generated plasma flows. With these boundary conditions we find the equilibrium without a flux accumulation (i.e., with constant magnetic field component normal to the current sheet) to develop an apparently resistive mode accompanied by tailward plasma flows. At the same time, the equilibria with a Bz hump of sufficiently large amplitude develop a different, ideal, mode characterized by spontaneous generation of earthward plasma flows and an exponential growth of the corresponding electric field. This growth is qualitatively similar to the corresponding fully kinetic simulations although no explosive growth of

  16. Heat transfer including radiation and slag particles evolution in MHD channel-I

    SciTech Connect

    Im, K H; Ahluwalia, R K

    1980-01-01

    Accurate estimates of convective and radiative heat transfer in the magnetohydrodynamic channel are provided. Calculations performed for a base load-size channel indicate that heat transfer by gas radiation almost equals that by convection for smooth walls, and amounts to 70% as much as the convective heat transfer for rough walls. Carbon dioxide, water vapor, and potassium atoms are the principal participating gases. The evolution of slag particles by homogeneous nucleation and condensation is also investigated. The particle-size spectrum so computed is later utilized to analyze the radiation enhancement by slag particles in the MHD diffuser. The impact of the slag particle spectrum on the selection of a workable and design of an efficient seed collection system is discussed.

  17. Modeling of magnetic reconnection in the magnetotail using global MHD simulation with an effective resistivity model

    NASA Astrophysics Data System (ADS)

    Den, M.; Horiuchi, R.; Fujita, S.; Tanaka, T.

    2011-12-01

    Magnetic reconnection is considered to play an important role in space phenomena such as substorm in the Earth's magnetosphere. Tanaka and Fujita reproduced substorm evolution process by numerical simulation with the global MHD code [1]. In the MHD framework, the dissipation model is introduced for modeling of the kinetic effects. They found that the normalized reconnection viscosity, one of the dissipation model employed there, gave a large effect for the dipolarization, central phenomenon in the substorm development process, though that viscosity was assumed to be a constant parameter. It is well known that magnetic reconnection is controlled by microscopic kinetic mechanism. Frozen-in condition is broken due to particle kinetic effects and collisionless reconnection is triggered when current sheet is compressed as thin as ion kinetic scales under the influence of external driving flow [2, 3]. Horiuchi and his collaborators showed that reconnection electric field generated by microscopic physics evolves inside ion meandering scale so as to balance the flux inflow rate at the inflow boundary, which is controlled by macroscopic physics [2]. That is, effective resistivity generated through this process can be expressed by balance equation between micro and macro physics. In this paper, we perform substorm simulation by using the global MHD code developed by Tanaka [3] with this effective resistivity instead of the empirical resistivity model. We obtain the AE indices from simulation data, in which substorm onset can be seen clearly, and investigate the relationship between the substorm development and the effective resistivity model. [1] T. Tanaka, A, Nakamizo, A. Yoshikawa, S. Fujita, H. Shinagawa, H. Shimazu, T. Kikuchi, and K. K. Hashimoto, J. Geophys. Res. 115 (2010) A05220,doi:10.1029/2009JA014676. [2] W. Pei, R. Horiuchi, and T. Sato, Physics of Plasmas,Vol. 8 (2001), pp. 3251-3257. [3] A. Ishizawa, and R. Horiuchi, Phys. Rev. Lett., Vol. 95, 045003 (2005). [4

  18. Structure of the dayside reconnection layer in resistive MHD and hybrid models

    NASA Technical Reports Server (NTRS)

    Lin, Y.; Lee, L. C.

    1993-01-01

    Numerical simulations were performed to investigate the structure of the reconnection layer at the dayside magnetopause. Two typical cases are examined in detail; both are asymmetric in magnetic field and plasma density. In case 1, the guide fields in the magnetosheath and in the magnetosphere are set at zero and thus the tangential magnetic fields on the two sides of the initial current sheet are exactly antiparallel. In case 2, the angle between the tangential magnetic fields on the two sides of the initial current sheet is 145 deg. The results obtained from a resistive MHD model and from a hybrid model are found to be different. In the MHD simulation of case 1, a 2-4 intermediate shock is found to bound the reconnection layer on the magnetosheath side, while an Alfven wave pulse bounds the reconnection layer on the magnetospheric side. In case 2, it is found that a time-dependent intermediate shock (TDIS) bounds the reconnection layer on the magnetosheath side, with a slow expansion wave propagating behind. With the MHD simulations, in the general case in which the tangential magnetic fields on the two sides of the initial current sheet are not exactly antiparallel, a rotational discontinuity across which the tangential magnetic field rotates, a large angle is found to bound the reconnection layer on the magnetosheath side.

  19. Minimally implicit Runge-Kutta methods for Resistive Relativistic MHD

    NASA Astrophysics Data System (ADS)

    Aloy, Miguel-Á.; Cordero-Carrión, Isabel

    2016-05-01

    The Relativistic Resistive Magnetohydrodynamic (RRMHD) equations are a hyperbolic system of partial differential equations used to describe the dynamics of relativistic magnetized fluids with a finite conductivity. Close to the ideal magnetohydrodynamic regime, the source term proportional to the conductivity becomes potentially stiff and cannot be handled with standard explicit time integration methods. We propose a new class of methods to deal with the stiffness fo the system, which we name Minimally Implicit Runge-Kutta methods. These methods avoid the development of numerical instabilities without increasing the computational costs in comparison with explicit methods, need no iterative extra loop in order to recover the primitive (physical) variables, the analytical inversion of the implicit operator is trivial and the several stages can actually be viewed as stages of explicit Runge-Kutta methods with an effective time-step. We test these methods with two different one-dimensional test beds in varied conductivity regimes, and show that our second-order schemes satisfy the theoretical expectations.

  20. MHD computation of feedback of resistive-shell instabilities in the reversed field pinch

    SciTech Connect

    Zita, E.J.; Prager, S.C. . Plasma Physics Research); Ho, Y.L.; Schnack, D.D )

    1992-05-01

    MHD computation demonstrates that feedback can sustain reversal and reduce loop voltage in resistive-shell reversed field pinch (RFP) plasmas. Edge feedback on {approximately}2R/a tearing modes resonant near axis is found to restore plasma parameters to nearly their levels with a close-fitting conducting shell. When original dynamo modes are stabilized, neighboring tearing modes grow to maintain the RFP dynamo more efficiently. This suggests that experimentally observed limits on RFP pulselengths to the order of the shell time can be overcome by applying feedback to a few helical modes.

  1. Transient Phenomena of Disk MHD Generator due to Change of Load Resistance

    NASA Astrophysics Data System (ADS)

    Koka, Hidetoshi; Okuno, Yoshihiro; Yamasaki, Hiroyuki

    Results of experimental study on transient phenomena of the closed cycle disk MHD generator are described in this paper. The transient phenomena were caused by a step-like change of load resistance during a test time of the shock-tube driven disk MHD generator. The load resistance was changed by using an IGBT (Insulated Gate Bipolar Transistor) installed in a load circuit. When the load resistance was changed from 0.096Ω to 2.5Ω, an overshoot of the Hall output voltage and of the Hall electric field was observed, and a large fluctuation of static pressure was also observed. At the same time, a spike-like increase of cesium recombination continuum and line spectrum appeared just after the load change. Results of the quasi-one dimensional numerical simulation have indicated that the observed overshoot was caused by the following phenomena: 1) a steep reduction of the Hall current and a steep increase in both the Faraday current and the electrical conductivity, and 2) a slow reduction of gas velocity due to the enhanced retarding force. Furthermore, the measured spike-like increase of radiation intensity was ascribed to an increase of electron temperature and electron number density by a steep increase of Joule heating.

  2. Local Existence for the Non-Resistive MHD Equations in Nearly Optimal Sobolev Spaces

    NASA Astrophysics Data System (ADS)

    Fefferman, Charles L.; McCormick, David S.; Robinson, James C.; Rodrigo, Jose L.

    2017-02-01

    This paper establishes the local-in-time existence and uniqueness of solutions to the viscous, non-resistive magnetohydrodynamics (MHD) equations in {R^d}, where d = 2, 3, with initial data {B_0in H^s(R^d)} and {u_0in H^{s-1+ɛ}(R^d)} for {s > d/2} and any {0 < ɛ < 1}. The proof relies on maximal regularity estimates for the Stokes equation. The obstruction to taking {ɛ=0} is explained by the failure of solutions of the heat equation with initial data {u_0in H^{s-1}} to satisfy {uin L^1(0,T; H^{s+1})}; we provide an explicit example of this phenomenon.

  3. MHD Instabilities Occurring Near/AT the Transport Barrier, Including Loss of Confinement in H-Modes

    SciTech Connect

    L. L. Lao

    1999-09-01

    In configurations with transport barriers the improved edge and core confinement leads to large pressure gradient and large edge bootstrap current density which often drive magnetohydrodynamic (MHD) instabilities terminating the discharge or reducing the discharge performance. The edge and the core transport barriers deteriorate or are completely lost. In this presentation, recent experimental and theoretical developments concerning MHD instabilities occurring near/at the edge and the core transport barriers are summarized emphasizing the dominant instabilities and the comparison with theory.

  4. MHD Simulations of Coronal Supra-arcade Downflows Including Anisotropic Thermal Conduction

    NASA Astrophysics Data System (ADS)

    Zurbriggen, E.; Costa, A.; Esquivel, A.; Schneiter, M.; Cécere, M.

    2016-11-01

    Coronal supra-arcade downflows (SADs) are observed as dark trails descending toward hot turbulent-fan-shaped regions. Due to the large temperature values and gradients in these fan regions, the thermal conduction (TC) should be very efficient. While several models have been proposed to explain the triggering and the evolution of SADs, none of these scenarios address a systematic consideration of TC. Thus, we accomplish this task numerically simulating the evolution of SADs within this framework. That is, SADs are conceived as voided (subdense) cavities formed by nonlinear waves triggered by downflowing bursty localized reconnection events in a perturbed hot fan. We generate a properly turbulent fan, obtained by a stirring force that permits control of the energy and vorticity input in the medium where SADs develop. We include anisotropic TC and consider plasma properties consistent with observations. Our aim is to study whether it is possible to prevent SADs from vanishing by thermal diffusion. We find that this will be the case, depending on the turbulence parameters, in particular if the magnetic field lines are able to envelope the voided cavities, thermally isolating them from the hot environment. Velocity shear perturbations that are able to generate instabilities of the Kelvin-Helmholtz type help to produce magnetic islands, extending the lifetime of SADs.

  5. Global well-posedness for the incompressible MHD equations with density-dependent viscosity and resistivity coefficients

    NASA Astrophysics Data System (ADS)

    Si, Xin; Ye, Xia

    2016-10-01

    This paper concerns an initial-boundary value problem of the inhomogeneous incompressible MHD equations in a smooth bounded domain. The viscosity and resistivity coefficients are density-dependent. The global well-posedness of strong solutions is established, provided the initial norms of velocity and magnetic field are suitably small in some sense, or the lower bound of the transport coefficients are large enough. More importantly, there is not any smallness condition on the density and its gradient.

  6. Supersonic MHD generator system

    SciTech Connect

    Rahman, M.A.

    1983-11-29

    An improved MHD electrical power generating system of the type having a MHD topping cycle and a steam generating bottoming cycle is disclosed. The system typically includes a combustion system, a conventional MHD generator and a first diffuser radiant boiler. The improvement comprises a first supersonic MHD generator and ramjet engine configuration operatively connected in series with each other and with the conventional MHD generator. The first supersonic MHD generator and ramjet engine configuration increase the power output and improve the operating efficiency of the electrical generating system. A diffuser system is also disclosed which is in fluid communication with the supersonic MHD generator and the ramjet engine for collecting bypass plasma gas to be used for heating a second radiant boiler adapted for powering a steam turbine generator.

  7. rHARM: Accretion and Ejection in Resistive GR-MHD

    NASA Astrophysics Data System (ADS)

    Qian, Qian; Fendt, Christian; Noble, Scott; Bugli, Matteo

    2017-01-01

    Turbulent magnetic diffusivity plays an important role for accretion disks and the launching of disk winds. We have implemented magnetic diffusivity and respective resistivity in the general relativistic MHD code HARM. This paper describes the theoretical background of our implementation, its numerical realization, our numerical tests, and preliminary applications. The test simulations of the new code rHARM are compared to an analytic solution of the diffusion equation and a classical shock tube problem. We have further investigated the evolution of the magnetorotational instability (MRI) in tori around black holes (BHs) for a range of magnetic diffusivities. We find an indication for a critical magnetic diffusivity (for our setup) beyond which no MRI develops in the linear regime and for which accretion of torus material to the BH is delayed. Preliminary simulations of magnetically diffusive thin accretion disks around Schwarzschild BHs that are threaded by a large-scale poloidal magnetic field show the launching of disk winds with mass fluxes of about 50% of the accretion rate. The disk magnetic diffusivity allows for efficient disk accretion that replenishes the mass reservoir of the inner disk area and thus allows for long-term simulations of wind launching for more than 5000 time units.

  8. Global existence and uniqueness theorem to 2-D incompressible non-resistive MHD system with non-equilibrium background magnetic field

    NASA Astrophysics Data System (ADS)

    Zhai, Cuili; Zhang, Ting

    2016-09-01

    In this article, we consider the global existence and uniqueness of the solution to the 2D incompressible non-resistive MHD system with non-equilibrium background magnetic field. Our result implies that a strong enough non-equilibrium background magnetic field will guarantee the stability of the nonlinear MHD system. Beside the classical energy method, the interpolation inequalities and the algebraic structure of the equations coming from the incompressibility of the fluid are crucial in our arguments.

  9. MHD-to-PIC transition for modeling of conduction and opening in a plasma opening switch

    NASA Astrophysics Data System (ADS)

    Schumer, J. W.

    2001-06-01

    The plasma opening switch (POS) is a critical element of some inductive-energy-storage pulsed-power generators. Detailed understanding of plasma redistribution and thinning during the POS conduction phase can be gained through magnetohydrodynamic fluid (MHD) simulations. As space-charge separation and kinetic effects become important late in the conduction phase (beginning of the opening phase), MHD methods become invalid and particle-in-cell (PIC) methods should be used. In this article, the applicability of MHD techniques is extended into PIC-like regimes by including non-ideal MHD phenomena such as the Hall effect and resistivity. The feasibility of the PIC technique is likewise extended into high-density, low-temperature MHD-like regimes by using a novel numerical cooling algorithm. At an appropriate time, an MHD-to-PIC transition must be accomplished in order to accurately simulate the POS opening phase. The mechanics for converting MHD (MACH2) output into PIC (MAGIC2d) input are introduced, as are the transition criteria determining when to perform this conversion. To establish these transition criteria, side-by-side MHD and PIC simulations are presented and compared. These separate simulations are then complemented by a proof-of-principle MHD-to-PIC transition, thereby demonstrating this MHD-to-PIC technique as a potentially viable tool for the simulation of POS plasmas. Practical limitations of the MHD-to-PIC transition method and applicability of the transition criteria to hybrid fluid-kinetic simulations are discussed.

  10. Including Religion in American History: Some Notes on Student Resistance.

    ERIC Educational Resources Information Center

    Talbert, Kevin M.; Romanowski, Michael H.

    2002-01-01

    Focuses on the importance of teaching religion in U.S. history courses. Discusses problems that teachers encounter when teaching religion, addresses the issue of students resisting learning about religion in the history classroom, and explores how teachers can reduce this resistance. Includes references. (CMK)

  11. Resistive Reduced MHD Modeling of Multi-Edge-Localized-Mode Cycles in Tokamak X -Point Plasmas

    NASA Astrophysics Data System (ADS)

    Orain, F.; Bécoulet, M.; Huijsmans, G. T. A.; Dif-Pradalier, G.; Hoelzl, M.; Morales, J.; Garbet, X.; Nardon, E.; Pamela, S.; Passeron, C.; Latu, G.; Fil, A.; Cahyna, P.

    2015-01-01

    The full dynamics of a multi-edge-localized-mode (ELM) cycle is modeled for the first time in realistic tokamak X -point geometry with the nonlinear reduced MHD code jorek. The diamagnetic rotation is found to be instrumental to stabilize the plasma after an ELM crash and to model the cyclic reconstruction and collapse of the plasma pressure profile. ELM relaxations are cyclically initiated each time the pedestal gradient crosses a triggering threshold. Diamagnetic drifts are also found to yield a near-symmetric ELM power deposition on the inner and outer divertor target plates, consistent with experimental measurements.

  12. An analytic scaling relation for the maximum tokamak elongation against n  =  0 MHD resistive wall modes

    NASA Astrophysics Data System (ADS)

    Lee, Jungpyo; Freidberg, Jeffrey; Cerfon, Antoine; Greenwald, Martin

    2017-06-01

    A highly elongated plasma is desirable in order to increase plasma pressure and energy confinement to maximize fusion power output. However, there is a limit to the maximum achievable elongation which is set by vertical instabilities driven by the n  =  0 MHD mode. This limit can be increased by optimizing several parameters characterizing the plasma and the wall. The purpose of our study is to explore how and to what extent this can be done. Specifically, we extend many earlier calculations of the n  =  0 mode and numerically determine scaling relations for the maximum elongation as a function of dimensionless parameters describing (1) the plasma profile ({βp} and l i ), (2) the plasma shape (ɛ and δ), (3) the wall radius (b/a) and (4) most importantly the feedback system capability parameter γ {τw} . These numerical calculations rely on a new formulation of n  =  0 MHD theory we recently developed (Freidberg et al 2015 J. Plasma Phys. 81 515810607, Lee et al 2015 J. Plasma Phys. 81 515810608) that reduces the 2D stability problem into a 1D problem. This method includes all the physics of the ideal MHD axisymmetric instability while reducing the computation time significantly, so that many parameters can be explored during the optimization process. The scaling relations we present include the effects of the optimal triangularity and the finite aspect ratio on the maximum elongation, and can be useful for determining optimized plasma shapes in current experiments and future tokamak designs.

  13. MHD simulations of three-dimensional resistive reconnection in a cylindrical plasma column

    NASA Astrophysics Data System (ADS)

    Striani, E.; Mignone, A.; Vaidya, B.; Bodo, G.; Ferrari, A.

    2016-11-01

    Magnetic reconnection is a plasma phenomenon where a topological rearrangement of magnetic field lines with opposite polarity results in dissipation of magnetic energy into heat, kinetic energy and particle acceleration. Such a phenomenon is considered as an efficient mechanism for energy release in laboratory and astrophysical plasmas. An important question is how to make the process fast enough to account for observed explosive energy releases. The classical model for steady state magnetic reconnection predicts reconnection times scaling as S1/2 (where S is the Lundquist number) and yields time-scales several order of magnitude larger than the observed ones. Earlier two-dimensional MHD simulations showed that for large Lundquist number the reconnection time becomes independent of S (`fast reconnection' regime) due to the presence of the secondary tearing instability that takes place for S ≳ 1 × 104. We report on our 3D MHD simulations of magnetic reconnection in a magnetically confined cylindrical plasma column under either a pressure balanced or a force-free equilibrium and compare the results with 2D simulations of a circular current sheet. We find that the 3D instabilities acting on these configurations result in a fragmentation of the initial current sheet in small filaments, leading to enhanced dissipation rate that becomes independent of the Lundquist number already at S ≃ 1 × 103.

  14. Plasmoid dynamics in 3D resistive MHD simulations of magnetic reconnection

    NASA Astrophysics Data System (ADS)

    Samtaney, R.; Loureiro, N. F.; Uzdensky, D. A.; Schekochihin, A. A.

    2012-04-01

    Magnetic reconnection is a well known plasma process believed to lie at the heart of a variety of phenomena such as sub-storms in the Earth's magnetosphere, solar/stellar and accretion-disk flares, sawteeth activity in fusion devices, etc. During reconnection, the global magnetic field topology changes rapidly, leading to the violent release of magnetic energy. Over the past few years, the basic understanding of this fundamental process has undergone profound changes. The validity of the most basic, and widely accepted, reconnection paradigm - the famous Sweet-Parker (SP) model, which predicts that, in MHD, reconnection is extremely slow, its rate scaling as S-1/2, where S is the Lundquist number of the system - has been called into question as it was analytically demonstrated that, for S ≫ 1, SP-like current sheets are violently unstable to the formation of a large number of secondary islands, or plasmoids. Subsequent numerical simulations in 2D have confirmed the validity of the linear theory, and shown that plasmoids quickly grow to become wider than the thickness of the original SP current sheet, thus effectively changing the underlying reconnection geometry. Ensuing numerical work has revealed that the process of plasmoid formation, coalescence and ejection from the sheet drastically modifies the steady state picture assumed by Sweet and Parker, and leads to the unexpected result that MHD reconnection is independent of S. In this talk, we review these recent developments and present results from three-dimensional simulations of high-Lundquist number reconnection in the presence of a guide field. A parametric study varying the strength of the guide field is presented. Plasmoid flux and width distribution functions are quantified and compared with corresponding two dimensional simulations.

  15. Modeling of fast neutral-beam-generated ion effects on MHD-spectroscopic observations of resistive wall mode stability in DIII-D plasmas

    SciTech Connect

    Turco, F. Hanson, J. M.; Navratil, G. A.; Turnbull, A. D.

    2015-02-15

    Experiments conducted at DIII-D investigate the role of drift kinetic damping and fast neutral beam injection (NBI)-ions in the approach to the no-wall β{sub N} limit. Modelling results show that the drift kinetic effects are significant and necessary to reproduce the measured plasma response at the ideal no-wall limit. Fast neutral-beam ions and rotation play important roles and are crucial to quantitatively match the experiment. In this paper, we report on the model validation of a series of plasmas with increasing β{sub N}, where the plasma stability is probed by active magnetohydrodynamic (MHD) spectroscopy. The response of the plasma to an externally applied field is used to probe the stable side of the resistive wall mode and obtain an indication of the proximity of the equilibrium to an instability limit. We describe the comparison between the measured plasma response and that calculated by means of the drift kinetic MARS-K code [Liu et al., Phys. Plasmas 15, 112503 (2008)], which includes the toroidal rotation, the electron and ion drift-kinetic resonances, and the presence of fast particles for the modelled plasmas. The inclusion of kinetic effects allows the code to reproduce the experimental results within ∼13% for both the amplitude and phase of the plasma response, which is a significant improvement with respect to the undamped MHD-only model. The presence of fast NBI-generated ions is necessary to obtain the low response at the highest β{sub N} levels (∼90% of the ideal no-wall limit). The toroidal rotation has an impact on the results, and a sensitivity study shows that a large variation in the predicted response is caused by the details of the rotation profiles at high β{sub N}.

  16. Extended-MHD modeling of diamagnetic-drift tearing instabilities

    NASA Astrophysics Data System (ADS)

    King, Jacob; Kruger, Scott

    2012-03-01

    We use analytics and computations with the NIMROD code to examine tearing stability in large-guide-field slab cases with a nonzero equilibrium pressure gradient. A well known result from drift-reduced MHD is the diamagnetic drift associated with the pressure gradient has a stabilizing influence were the dispersion relation becomes (γ+iφ*e)^3γ(γ+iφ*i)=γrMHD^5 [1]. Here φ*i and φ*e are the ion- and electron-diamagnetic frequencies and γrMHD is the tearing growth rate with a resistive-MHD model. Preliminary computational results with an unreduced extended-MHD model do not produce the expected drift-reduced result. For moderate values of φ*i (φ*i<=3γrMHD), the computations follow the dispersion relation that would result if the ∇pe term were not included in the drift-reduced parallel Ohm's law: (γ+iφ*e)^4(γ+iφ*i)=γrMHD^5. Analytics, guided by computational diagnostics, are used to examine the significant terms in the flux evolution equation and investigate the discrepancy with the drift-reduced result.[4pt] [1] For example Coppi, PoF 7, 1501 (1964); Biskamp, NF 18, 1059 (1978).

  17. Sugarcane aphid (Hemiptera: Aphididae): Host range and sorghum resistance including cross-resistance from greenbug sources

    USDA-ARS?s Scientific Manuscript database

    The graminous host range, and sources of sorghum plant resistance including cross resistance from greenbug, Schizaphis graminum (Rond.) sorghums, [Sorghum bicolor L.) Moench], were studied for the newly emerging sugarcane aphid Melanaphis sacchari, (Zehntner) in greenhouse no-choice experiments and ...

  18. MHD Stagnation point flows in the presence of resistivity and viscosity

    SciTech Connect

    Gratton, F.T.; Heyn, M.F.; Biernat, H.K.; Rijnbeek, R.P.; Gnavi, G. )

    1988-07-01

    The authors analyze the steady state situation in which two separate and counterstreaming plasmas (assumed to be incompressible) carrying antiparallel magnetic fields are separated by a resistive current layer. Exact solutions are presented which describe the stagnation point flow pattern and magnetic field behavior which result. They incorporate the effects of viscosity, which enables us to model flows with vorticity. The uniform plasma flow which is obtained at large distances from the current layer allows us to specify finite values of the asymptotic magnetic field. The exact solutions complement those of a different type obtained by B.U.O. Sonnerup and E.R. Priest (1975) which assume potential flow, i.e., zero vorticity. The results they obtain are discussed in relation to observational features at the Earth's magnetopause.

  19. Resistive tearing instability in electron MHD: application to neutron star crusts

    NASA Astrophysics Data System (ADS)

    Gourgouliatos, Konstantinos N.; Hollerbach, Rainer

    2016-12-01

    We study a resistive tearing instability developing in a system evolving through the combined effect of Hall drift in the electron magnetohydrodynamic limit and Ohmic dissipation. We explore first the exponential growth of the instability in the linear case and we find the fastest growing mode, the corresponding eigenvalues and dispersion relation. The instability growth rate scales as γ ∝ B2/3σ-1/3, where B is the magnetic field and σ the electrical conductivity. We confirm the development of the tearing resistive instability in the fully non-linear case, in a plane-parallel configuration where the magnetic field polarity reverses, through simulations of systems initiating in Hall equilibrium with some superimposed perturbation. Following a transient phase, during which there is some minor rearrangement of the magnetic field, the perturbation grows exponentially. Once the instability is fully developed, the magnetic field forms the characteristic islands and X-type reconnection points, where Ohmic decay is enhanced. We discuss the implications of this instability for the local magnetic field evolution in neutron stars' crusts, proposing that it can contribute to heating near the surface of the star, as suggested by models of magnetar post-burst cooling. In particular, we find that a current sheet a few metres thick, covering as little as 1 per cent of the total surface, can provide 1042 erg in thermal energy within a few days. We briefly discuss applications of this instability in other systems where the Hall effect operates such as protoplanetary discs and space plasmas.

  20. MHD generator electrode development

    NASA Astrophysics Data System (ADS)

    Retallick, F. D.; Dietrick, D. L.; Lloyd, I.; Rossing, B. R.; Smith, R.

    1981-08-01

    Metallurgical and engineering understanding of cold metallic electrode alternatives to the continued use of platinum as an anode clad material is discussed. The results of evaluating materials for MHD electrodes through use of a laboratory electrochemical and arc test are presented. Results for standard available materials as well as for some specially fabricated ones are presented. The development of a high temperature (11000 C to 14000 C) electrochemical test is outlined. Initial operation of the Westinghouse Electrode Systems Test Facility (WESTF), since major modification to include a magnet, is reported for a test section designed to operate as a small scale MHD generator and for test sections designed for the purpose of materials test evaluation in the operating MHD plasma environment.

  1. MHD Program Plan, FY 1992

    NASA Astrophysics Data System (ADS)

    1991-10-01

    The current MHD program being implemented is a result of a consensus established in public meetings held by the Department of Energy in 1984. Essential elements of the current program include the following: (1) develop technical and environmental data for the integrated MHD topping cycle system through POC testing (1,000 hours); (2) develop technical and environmental data for the integrated MHD bottoming cycle sub system through POC testing (4,000 hours); (3) design, construct, and operate a seed regeneration POC facility (SRPF) capable of processing spent seed materials from the MHD bottoming cycle; (4) prepare conceptual designs for a site specific MHD retrofit plant; and (5) continue system studies and supporting research necessary for system testing. The current MHD program continues to be directed toward coal fired power plant applications, both stand-alone and retrofit. Development of a plant should enhance the attractiveness of MHD for applications other than electrical power. MHD may find application in electrical energy intensive industries and in the defense sector.

  2. Salient issues of edge physics pertaining to loss of confinement: A resistive MHD analysis

    SciTech Connect

    Thayer, D.R.

    1991-01-01

    The progress that has been made during this fiscal year is significant in the area of tokamak edge plasma transport. The drift-rippling mode model of edge turbulent transport was extended. In particular, the research areas on which were concentrated include the following topics: (1) The theoretical investigation of the radiatively enhanced transport due to the effects of impurity driven radiation instabilities has been expanded to include a situation with multiple impurities (such as carbon, C{sup 4+}, and oxygen, O{sup 6+}); (2) In order to validate the use of the impurity radiation input from the tokamak bolometer experiments in the theoretical edge turbulent transport calculations, the analysis that is utilized to transform impurity brightness data to radiated power profiles has been checked for state population and Abel inversion correctness; (3) The drift-rippling model of edge turbulent transport has been extended to include ionization particle sources in addition to the impurity driven thermal instability drive; and (4) The detailed limiter and realistic edge geometric effects on the edge turbulent transport has been included in the drift-rippling model.

  3. Investigation of island formation due to RMPs in DIII-D plasmas with the SIESTA resistive MHD equilibrium code

    NASA Astrophysics Data System (ADS)

    Hirshman, S. P.; Shafer, M. W.; Seal, S. K.; Canik, J. M.

    2016-04-01

    > The SIESTA magnetohydrodynamic (MHD) equilibrium code has been used to compute a sequence of ideally stable equilibria resulting from numerical variation of the helical resonant magnetic perturbation (RMP) applied to an axisymmetric DIII-D plasma equilibrium. Increasing the perturbation strength at the dominant , resonant surface leads to lower MHD energies and increases in the equilibrium island widths at the (and sidebands) surfaces, in agreement with theoretical expectations. Island overlap at large perturbation strengths leads to stochastic magnetic fields which correlate well with the experimentally inferred field structure. The magnitude and spatial phase (around the dominant rational surfaces) of the resonant (shielding) component of the parallel current are shown to change qualitatively with the magnetic island topology.

  4. Investigation of island formation due to RMPs in DIII-D plasmas with the SIESTA resistive MHD equilibrium code

    DOE PAGES

    Hirshman, S. P.; Shafer, M. W.; Seal, S. K.; ...

    2016-03-03

    The SIESTA magnetohydrodynamic (MHD) equilibrium code has been used to compute a sequence of ideally stable equilibria resulting from numerical variation of the helical resonant magnetic perturbation (RMP) applied to an axisymmetric DIII-D plasma equilibrium. Increasing the perturbation strength at the dominant m=2, n=-1 , resonant surface leads to lower MHD energies and increases in the equilibrium island widths at the m=2 (and sidebands) surfaces, in agreement with theoretical expectations. Island overlap at large perturbation strengths leads to stochastic magnetic fields which correlate well with the experimentally inferred field structure. The magnitude and spatial phase (around the dominant rational surfaces)more » of the resonant (shielding) component of the parallel current are shown to change qualitatively with the magnetic island topology.« less

  5. Investigation of island formation due to RMPs in DIII-D plasmas with the SIESTA resistive MHD equilibrium code

    SciTech Connect

    Hirshman, S. P.; Shafer, M. W.; Seal, S. K.; Canik, J. M.

    2016-03-03

    The SIESTA magnetohydrodynamic (MHD) equilibrium code has been used to compute a sequence of ideally stable equilibria resulting from numerical variation of the helical resonant magnetic perturbation (RMP) applied to an axisymmetric DIII-D plasma equilibrium. Increasing the perturbation strength at the dominant m=2, n=-1 , resonant surface leads to lower MHD energies and increases in the equilibrium island widths at the m=2 (and sidebands) surfaces, in agreement with theoretical expectations. Island overlap at large perturbation strengths leads to stochastic magnetic fields which correlate well with the experimentally inferred field structure. The magnitude and spatial phase (around the dominant rational surfaces) of the resonant (shielding) component of the parallel current are shown to change qualitatively with the magnetic island topology.

  6. MHD Energy Bypass Scramjet Engine

    NASA Technical Reports Server (NTRS)

    Mehta, Unmeel B.; Bogdanoff, David W.; Park, Chul; Arnold, Jim (Technical Monitor)

    2001-01-01

    Revolutionary rather than evolutionary changes in propulsion systems are most likely to decrease cost of space transportation and to provide a global range capability. Hypersonic air-breathing propulsion is a revolutionary propulsion system. The performance of scramjet engines can be improved by the AJAX energy management concept. A magneto-hydro-dynamics (MHD) generator controls the flow and extracts flow energy in the engine inlet and a MHD accelerator downstream of the combustor accelerates the nozzle flow. A progress report toward developing the MHD technology is presented herein. Recent theoretical efforts are reviewed and ongoing experimental efforts are discussed. The latter efforts also include an ongoing collaboration between NASA, the US Air Force Research Laboratory, US industry, and Russian scientific organizations. Two of the critical technologies, the ionization of the air and the MHD accelerator, are briefly discussed. Examples of limiting the combustor entrance Mach number to a low supersonic value with a MHD energy bypass scheme are presented, demonstrating an improvement in scramjet performance. The results for a simplified design of an aerospace plane show that the specific impulse of the MHD-bypass system is better than the non-MHD system and typical rocket over a narrow region of flight speeds and design parameters. Equilibrium ionization and non-equilibrium ionization are discussed. The thermodynamic condition of air at the entrance of the engine inlet determines the method of ionization. The required external power for non-equilibrium ionization is computed. There have been many experiments in which electrical power generation has successfully been achieved by magneto-hydrodynamic (MHD) means. However, relatively few experiments have been made to date for the reverse case of achieving gas acceleration by the MHD means. An experiment in a shock tunnel is described in which MHD acceleration is investigated experimentally. MHD has several

  7. Plasma stability theory including the resistive wall effects

    NASA Astrophysics Data System (ADS)

    Pustovitov, V. D.

    2015-12-01

    > Plasma stabilization due to a nearby conducting wall can provide access to better performance in some scenarios in tokamaks. This was proved by experiments with an essential gain in and demonstrated as a long-lasting effect at sufficiently fast plasma rotation in the DIII-D tokamak (see, for example, Strait et al., Nucl. Fusion, vol. 43, 2003, pp. 430-440). The rotational stabilization is the central topic of this review, though eventually the mode rotation gains significance. The analysis is based on the first-principle equations describing the energy balance with dissipation in the resistive wall. The method emphasizes derivation of the dispersion relations for the modes which are faster than the conventional resistive wall modes, but slower than the ideal magnetohydrodynamics modes. Both the standard thin wall and ideal-wall approximations are not valid in this range. Here, these are replaced by an approach incorporating the skin effect in the wall. This new element in the stability theory makes the energy sink a nonlinear function of the complex growth rate. An important consequence is that a mode rotating above a critical level can provide a damping effect sufficient for instability suppression. Estimates are given and applications are discussed.

  8. MHD turbulent processes

    NASA Technical Reports Server (NTRS)

    Montgomery, David

    1988-01-01

    Three areas of study in MHD turbulence are considered. These are the turbulent relaxation of the toroidal Z pinch, density fluctuations in MHD fluids, and MHD cellular automata. A Boolean computer game that updates a cellular representation in parallel and that has macroscopic averages converging to solutions of the two-dimensional MHD equations is discussed.

  9. Nuclear MHD Converter

    DTIC Science & Technology

    2007-11-02

    model the Power Conversion Unit (gas reactor + nozzle and MHD channel), and the cross sections derived from Task 1.. The configuration extends ...8 1.1 Project Objectives 8 1.2 Report Organization 9 Tables and Figures 10 2 PROJECT DESCRIPTION 11 3 REFLECTOR MODELING 13 3.1 Symbols...outlet. This conclusion remains true even if the effect of dissociation and attachment are included in the numerical model . Furthermore, a

  10. Resistive reduced MHD modeling of multi-edge-localized-mode cycles in Tokamak X-point plasmas.

    PubMed

    Orain, F; Bécoulet, M; Huijsmans, G T A; Dif-Pradalier, G; Hoelzl, M; Morales, J; Garbet, X; Nardon, E; Pamela, S; Passeron, C; Latu, G; Fil, A; Cahyna, P

    2015-01-23

    The full dynamics of a multi-edge-localized-mode (ELM) cycle is modeled for the first time in realistic tokamak X-point geometry with the nonlinear reduced MHD code jorek. The diamagnetic rotation is found to be instrumental to stabilize the plasma after an ELM crash and to model the cyclic reconstruction and collapse of the plasma pressure profile. ELM relaxations are cyclically initiated each time the pedestal gradient crosses a triggering threshold. Diamagnetic drifts are also found to yield a near-symmetric ELM power deposition on the inner and outer divertor target plates, consistent with experimental measurements.

  11. Modeling of fast neutral-beam-generated ion effects on MHD-spectroscopic observations of resistive wall mode stability in DIII-D plasmas [Modeling of fast neutral-beam-generated ion effects on MHD spectroscopic observations of RWM stability in DIII-D plasmas

    DOE PAGES

    Turco, Francesca; Turnbull, Alan D.; Hanson, Jeremy M.; ...

    2015-02-03

    Experiments conducted at DIII-D investigate the role of drift kinetic damping and fast neutral beam injection (NBI)-ions in the approach to the no-wall βN limit. Modelling results show that the drift kinetic effects are significant and necessary to reproduce the measured plasma response at the ideal no-wall limit. Fast neutral-beam ions and rotation play important roles and are crucial to quantitatively match the experiment. In this paper, we report on the model validation of a series of plasmas with increasing βN, where the plasma stability is probed by active magnetohydrodynamic (MHD) spectroscopy. The response of the plasma to an externallymore » applied field is used to probe the stable side of the resistive wall mode and obtain an indication of the proximity of the equilibrium to an instability limit. We describe the comparison between the measured plasma response and that calculated by means of the drift kinetic MARS-K code, which includes the toroidal rotation, the electron and ion drift-kinetic resonances, and the presence of fast particles for the modelled plasmas. The inclusion of kinetic effects allows the code to reproduce the experimental results within ~13% for both the amplitude and phase of the plasma response, which is a significant improvement with respect to the undamped MHD-only model. The presence of fast NBI-generated ions is necessary to obtain the low response at the highest βN levels (~90% of the ideal no-wall limit). Finally, the toroidal rotation has an impact on the results, and a sensitivity study shows that a large variation in the predicted response is caused by the details of the rotation profiles at high βN.« less

  12. Modeling of fast neutral-beam-generated ion effects on MHD-spectroscopic observations of resistive wall mode stability in DIII-D plasmas [Modeling of fast neutral-beam-generated ion effects on MHD spectroscopic observations of RWM stability in DIII-D plasmas

    SciTech Connect

    Turco, Francesca; Turnbull, Alan D.; Hanson, Jeremy M.; Navratil, Gerald A.

    2015-02-03

    Experiments conducted at DIII-D investigate the role of drift kinetic damping and fast neutral beam injection (NBI)-ions in the approach to the no-wall βN limit. Modelling results show that the drift kinetic effects are significant and necessary to reproduce the measured plasma response at the ideal no-wall limit. Fast neutral-beam ions and rotation play important roles and are crucial to quantitatively match the experiment. In this paper, we report on the model validation of a series of plasmas with increasing βN, where the plasma stability is probed by active magnetohydrodynamic (MHD) spectroscopy. The response of the plasma to an externally applied field is used to probe the stable side of the resistive wall mode and obtain an indication of the proximity of the equilibrium to an instability limit. We describe the comparison between the measured plasma response and that calculated by means of the drift kinetic MARS-K code, which includes the toroidal rotation, the electron and ion drift-kinetic resonances, and the presence of fast particles for the modelled plasmas. The inclusion of kinetic effects allows the code to reproduce the experimental results within ~13% for both the amplitude and phase of the plasma response, which is a significant improvement with respect to the undamped MHD-only model. The presence of fast NBI-generated ions is necessary to obtain the low response at the highest βN levels (~90% of the ideal no-wall limit). Finally, the toroidal rotation has an impact on the results, and a sensitivity study shows that a large variation in the predicted response is caused by the details of the rotation profiles at high βN.

  13. MHD edge instabilities in toroidal plasmas

    NASA Astrophysics Data System (ADS)

    Sugiyama, Linda

    2015-11-01

    Different types of MHD edge instabilities in different toroidal magnetically confined plasmas are compared. Large scale numerical simulations show that the nonlinear evolution of an unstable edge mode in a shaped plasma with a single X-point and a surrounding open field line region has a number of common features in the full resistive MHD model for strongly unstable and weaker instabilities. These include the relation of the nonlinear mode structure and dominant toroidal harmonics to the linear eigenmode spectrum, the effects of the mode on reducing the edge pressure or density gradient, the inward penetration of a ballooning-type perturbation into the plasma interior, and the potential to drive a coherent axisymmetric poloidal rotation of the outer part of the plasma, exhibited at different strengths. The results can be compared to experiment to estimate the usefulness and validity of the MHD model for predicting edge stability and instability properties. Work supported by the U.S. DOE OFES under Awards DE-SC-0007883, DE-FG02-04ER54802, and DE-SC-0008737. Some computation carried out at NERSC.

  14. Investigation of island formation due to RMPs in DIII-D plasmas with the SIESTA resistive MHD equilibrium code

    SciTech Connect

    Hirshman, S. P.; Shafer, M. W.; Seal, S. K.; Canik, J. M.

    2016-03-03

    The SIESTA magnetohydrodynamic (MHD) equilibrium code has been used to compute a sequence of ideally stable equilibria resulting from numerical variation of the helical resonant magnetic perturbation (RMP) applied to an axisymmetric DIII-D plasma equilibrium. Increasing the perturbation strength at the dominant $m=2$,$n=-1$ resonant surface leads to lower MHD energies and increases in the equilibrium island widths at the $m=2$ (and sidebands) surfaces, in agreement with theoretical expectations. Island overlap at large perturbation strengths leads to stochastic magnetic fields which correlate well with the experimentally inferred field structure. The magnitude and spatial phase (around the dominant rational surfaces) of the resonant (shielding) component of the parallel current are shown to change qualitatively with the magnetic island topology.

  15. Rings and gaps produced by variable magnetic disc winds and avalanche accretion streams - I. Axisymmetric resistive MHD simulations

    NASA Astrophysics Data System (ADS)

    Suriano, Scott S.; Li, Zhi-Yun; Krasnopolsky, Ruben; Shang, Hsien

    2017-07-01

    Rings and gaps are being observed in an increasing number of discs around young stellar objects. We illustrate the formation of such radial structures through idealized, 2D (axisymmetric) resistive magnetohydrodynamic simulations of coupled disc-wind systems threaded by a relatively weak poloidal magnetic field (plasma-β ˜ 103). We find two distinct modes of accretion depending on the resistivity and field strength. A small resistivity or high field strength promotes the development of rapidly infalling 'avalanche accretion streams' in a vertically extended disc envelope that dominates the dynamics of the system, especially the mass accretion. The streams are suppressed in simulations with larger resistivities or lower field strengths, where most of the accretion instead occurs through a laminar disc. In these simulations, the disc accretion is driven mainly by a slow wind that is typically accelerated by the pressure gradient from a predominantly toroidal magnetic field. Both wind-dominated ISM: jets and outflows and stream-dominated modes of accretion create prominent features in the surface density distribution of the disc, including rings and gaps, with a strong spatial variation of the magnetic flux relative to the mass. Regions with low mass-to-flux ratios accrete quickly, leading to the development of gaps, whereas regions with higher mass-to-flux ratios tend to accrete more slowly, allowing matter to accumulate and form dense rings. In some cases, avalanche accretion streams are observed to produce dense rings directly through continuous feeding. We discuss the implications of ring and gap formation driven by winds and streams on grain growth and planet formation.

  16. MHD Spectroscopy

    SciTech Connect

    Heeter, R F; Fasoli, A; Testa, D; Sharapov, S; Berk, H L; Breizman, B; Gondhalekar, A; Mantsinen, M

    2004-03-23

    Experiments are conducted on the JET tokamak to assess the diagnostic potential of MHD active and passive spectroscopy, for the plasma bulk and its suprathermal components, using Alfv{acute e}n Eigenmodes (AEs) excited by external antennas and by energetic particles. The measurements of AE frequencies and mode numbers give information on the bulk plasma. Improved equilibrium reconstruction, in particular in terms of radial profiles of density and safety factor, is possible from the comparison between the antenna driven spectrum and that calculated theoretically. Details of the time evolution of the non-monotonic safety factor profile in advanced scenarios can be reconstructed from the frequency of ICRH-driven energetic particle modes. The plasma effective mass can be inferred from the resonant frequency of externally driven AEs in discharges with similar equilibrium profiles. The stability thresholds and the nonlinear development of the instabilities can give clues on energy and spatial distribution of the fast particle population. The presence of unstable AEs provides lower limits in the energy of ICRH generated fast ion tails. Fast ion pressure gradients and their evolution can be inferred from the stability of AEs at different plasma radial positions. Finally, the details of the AE spectrum in the nonlinear stage can be used to obtain information about the fast particle velocity space diffusion.

  17. Output from MHD Models

    NASA Astrophysics Data System (ADS)

    Vlahakis, Nektarios

    2010-03-01

    Outflows emanating from the environment of stellar or galactic objects are a widespread phenomenon in astrophysics. Their morphology ranges from nearly spherically symmetric winds to highly collimated jets. In some cases, e.g., in jets associated with young stellar objects, the bulk outflow speeds are nonrelativistic, while in others, e.g., in jets associated with active galactic nuclei or gamma-ray bursts, it can even be highly relativistic. The main driving mechanism of collimated outflows is likely related to magnetic fields. These fields are able to tap the rotational energy of the compact object or disk, accelerate, and collimate matter ejecta. To zeroth order these outflows can be described by the highly intractable theory of magnetohydrodynamics (MHD). Even in systems where the assumptions of zero resistivity (ideal MHD), steady state, axisymmetry, one fluid description, and polytropic equation of state are applicable, the problem remains difficult. In this case the problem reduces to only two equations, corresponding to the two components of the momentum equation along the flow and in the direction perpendicular to the magnetic field (transfield direction). The latter equation is the most difficult to solve, but also the most important. It answers the question on the degree of the collimation, but also crucially affects the solution of the first, the acceleration efficiency and the bulk velocity of the flow. The first and second parts of this chapter refer to nonrelativistic and relativistic flows, respectively. These Parts can be read independently. In each one, the governing equations are presented and discussed, focusing on the case of flows that are magnetically dominated near the central source. The general characteristics of the solutions in relation to the acceleration and collimation mechanisms are analyzed. As specific examples of exact solutions of the full system of the MHD equations that satisfy all the analyzed general characteristics, self

  18. MHD Power Generation

    ERIC Educational Resources Information Center

    Kantrowitz, Arthur; Rosa, Richard J.

    1975-01-01

    Explains the operation of the Magnetohydrodynamic (MHD) generator and advantages of the system over coal, oil or nuclear powered generators. Details the development of MHD generators in the United States and Soviet Union. (CP)

  19. MHD Power Generation

    ERIC Educational Resources Information Center

    Kantrowitz, Arthur; Rosa, Richard J.

    1975-01-01

    Explains the operation of the Magnetohydrodynamic (MHD) generator and advantages of the system over coal, oil or nuclear powered generators. Details the development of MHD generators in the United States and Soviet Union. (CP)

  20. Modeling MHD Equilibrium and Dynamics with Non-Axisymmetric Resistive Walls in LTX and HBT-EP

    NASA Astrophysics Data System (ADS)

    Hansen, C.; Levesque, J.; Bialek, J.; Boyle, D. P.; Schmitt, J.

    2016-10-01

    In experimental magnetized plasmas, currents in the first wall, vacuum vessel, and other conducting structures can have a strong influence on plasma shape and dynamics. These effects are complicated by the 3D nature of these structures, which dictate available current paths. Results from simulations to study the effect of external currents on plasmas in two different experiments will be presented: 1) The arbitrary geometry, 3D extended MHD code PSI-Tet is applied to study linear and non-linear plasma dynamics in the High Beta Tokamak (HBT-EP) focusing on toroidal asymmetries in the adjustable conducting wall. 2) Equilibrium reconstructions of the Lithium Tokamak eXperiment (LTX) in the presence of non-axisymmetric eddy currents. An axisymmetric model is used to reconstruct the plasma equilibrium, using the PSI-Tri code, along with a set of fixed eddy current distributions. Current distributions are generated using 3D time-dependent, thin-wall, eddy current simulations using VALEN or PSI-Tet. Simulations of detailed experimental geometries are enabled by use of the PSI-Tet code, which employs a high order finite element method on unstructured tetrahedral grids that are generated directly from CAD models. Further development of PSI-Tet will also be presented. Work supported by US DOE.

  1. Magnetohydrodynamic (MHD) channel corner seal

    DOEpatents

    Spurrier, Francis R.

    1980-01-01

    A corner seal for an MHD duct includes a compressible portion which contacts the duct walls and an insulating portion which contacts the electrodes, sidewall bars and insulators. The compressible portion may be a pneumatic or hydraulic gasket or an open-cell foam rubber. The insulating portion is segmented into a plurality of pieces of the same thickness as the electrodes, insulators and sidewall bars and aligned therewith, the pieces aligned with the insulator being of a different size from the pieces aligned with the electrodes and sidewall bars to create a stepped configuration along the corners of the MHD channel.

  2. Cometary MHD and chemistry

    NASA Technical Reports Server (NTRS)

    Wegmann, R.; Schmidt, H. U.; Huebner, W. F.; Boice, D. C.

    1987-01-01

    An MHD and chemical comet-coma model was developed, applying the computer program of Huebner (1985) for the detailed chemical evolution of a spherically expanding coma and the program of Schmidt and Wegman (1982) and Wegman (1987) for the MHD flow of plasma and magnetic field in a comet to the Giotto-mission data on the ion abundances measured by the HIS ion mass spectrometer. The physics and chemistry of the coma are modeled in great detail, including photoprocesses, gas-phase chemical kinetics, energy balance with a separate electron temperature, multifluid hydrodynamics with a transition to free molecular flow, fast-streaming atomic and molecular hydrogen, counter and cross streaming of the ionized species relative to the neutral species in the coma-solar wind interaction region with momentum exchange by elastic collisions, mass-loading through ion pick-up, and Lorentz forces of the advected magnetic field. The results, both inside and outside of the contact surface, are discussed and compared with the relevant HIS ion mass spectra.

  3. Explosive MHD Generators

    NASA Astrophysics Data System (ADS)

    Lebedev, E. F.; Ostashev, V. E.; Fortov, V. E.

    2004-11-01

    Explosive driven MHD generators (EMHD) occupy an intermediate position between destroyed Explosive Flux Compression Generators and solid-propellant- pulsed MHD generators. Studies revealed the negative consequences of destroying a plasma liner through Rayleigh-Taylor instability. The real efficiency of conversion of condensed HE charge chemical energy reaches ~10% if the magnetic field in a MHD channel is approximately 8-10 T. Accommodation of 20-30 linear MHD channels into a toroidal magnet seems to be optimal for EMHD generator design. This device may operate repeatedly with a frequency of up to 6.5×103pps.

  4. Electric fields, weighting fields, signals and charge diffusion in detectors including resistive materials

    NASA Astrophysics Data System (ADS)

    Riegler, W.

    2016-11-01

    In this report we discuss static and time dependent electric fields in detector geometries with an arbitrary number of parallel layers of a given permittivity and weak conductivity. We derive the Green's functions i.e. the field of a point charge, as well as the weighting fields for readout pads and readout strips in these geometries. The effect of `bulk' resistivity on electric fields and signals is investigated. The spreading of charge on thin resistive layers is also discussed in detail, and the conditions for allowing the effect to be described by the diffusion equation is discussed. We apply the results to derive fields and induced signals in Resistive Plate Chambers, MICROMEGAS detectors including resistive layers for charge spreading and discharge protection as well as detectors using resistive charge division readout like the MicroCAT detector. We also discuss in detail how resistive layers affect signal shapes and increase crosstalk between readout electrodes.

  5. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-01-01

    The overall objective of the project is to design and construct prototypical hardware for an integrated MHD topping cycle, and conduct long duration proof-of-concept tests of integrated system at the US DOE Component Development and Integration Facility in Butte, Montana. The results of the long duration tests will augment the existing engineering design data base on MHD power train reliability, availability, maintainability, and performance, and will serve as a basis for scaling up the topping cycle design to the next level of development, an early commercial scale power plant retrofit. The components of the MHD power train to be designed, fabricated, and tested include: A slagging coal combustor with a rated capacity of 50 MW thermal input, capable of operation with an Eastern (Illinois {number sign}6) or Western (Montana Rosebud) coal, a segmented supersonic nozzle, a supersonic MHD channel capable of generating at least 1.5 MW of electrical power, a segmented supersonic diffuser section to interface the channel with existing facility quench and exhaust systems, a complete set of current control circuits for local diagonal current control along the channel, and a set of current consolidation circuits to interface the channel with the existing facility inverter.

  6. MHD Technology Transfer, Integration and Review Committee

    SciTech Connect

    Not Available

    1989-10-01

    As part of the MHD Integrated Topping Cycle (ITC) project, TRW was given the responsibility to organize, charter and co-chair, with the Department of Energy (DOE), an MHD Technology Transfer, Integration and Review Committee (TTIRC). The Charter of the TTIRC, which was approved by the DOE in June 1988 and distributed to the committee members, is included as part of this Summary. As stated in the Charter, the purpose of this committee is to: (1) review all Proof-of-Concept (POC) projects and schedules in the national MHD program; to assess their compatibility with each other and the first commercial MHD retrofit plant; (2) establish and implement technology transfer formats for users of this technology; (3) identify interfaces, issues, and funding structures directly impacting the success of the commercial retrofit; (4) investigate and identify the manner in which, and by whom, the above should be resolved; and (5) investigate and assess other participation (foreign and domestic) in the US MHD Program. The DOE fiscal year 1989 MHD Program Plan Schedule is included at the end of this Summary. The MHD Technology Transfer, Integration and Review Committee's activities to date have focused primarily on the technology transfer'' aspects of its charter. It has provided a forum for the dissemination of technical and programmatic information among workers in the field of MHD and to the potential end users, the utilities, by holding semi-annual meetings. The committee publishes this semi-annual report, which presents in Sections 2 through 11 capsule summaries of technical progress for all DOE Proof-of-Concept MHD contracts and major test facilities.

  7. Lattice Boltzmann Representations of MHD Turbulence

    NASA Astrophysics Data System (ADS)

    Vahala, George; Vahala, Linda; Soe, Min; Flint, Christopher

    2013-10-01

    Lattice Botlzmann algorithms are an ideally parallelized method for the solutions of macroscopic nonlinear equations of physics - like resistive MHD. In its simplest LB representation one introduces a scalar distribution for the density-velocity fields and a vector distribution for the magnetic field. An important feature is that gradients of certain macroscopic fields can be represented by local moments of the mesoscopic distribution functions. In particular, div B = 0 can be exactly enforced to machine accuracy, without any divergence cleaning. One of the problems facing the explicit LB code is numerical instabilities. Methods to permit strong turbulence simulations include: (a) moving from a single BGK to multiple collisional relaxation, (b) quasi-equilibria and central moment enhanced LB representations. The LB turbulence modeling of Ansumali et al. to Navier-Stokes turbulence will be extended to MHD in which in its noted that filtering and Chapman-Enskog limits do not commute. In the NS-case, it leads to unique Samgorinsky closure scheme, with definite filter width.

  8. Chemical solver to compute molecule and grain abundances and non-ideal MHD resistivities in prestellar core-collapse calculations

    NASA Astrophysics Data System (ADS)

    Marchand, P.; Masson, J.; Chabrier, G.; Hennebelle, P.; Commerçon, B.; Vaytet, N.

    2016-07-01

    We develop a detailed chemical network relevant to calculate the conditions that are characteristic of prestellar core collapse. We solve the system of time-dependent differential equations to calculate the equilibrium abundances of molecules and dust grains, with a size distribution given by size-bins for these latter. These abundances are used to compute the different non-ideal magneto-hydrodynamics resistivities (ambipolar, Ohmic and Hall), needed to carry out simulations of protostellar collapse. For the first time in this context, we take into account the evaporation of the grains, the thermal ionisation of potassium, sodium, and hydrogen at high temperature, and the thermionic emission of grains in the chemical network, and we explore the impact of various cosmic ray ionisation rates. All these processes significantly affect the non-ideal magneto-hydrodynamics resistivities, which will modify the dynamics of the collapse. Ambipolar diffusion and Hall effect dominate at low densities, up to nH = 1012 cm-3, after which Ohmic diffusion takes over. We find that the time-scale needed to reach chemical equilibrium is always shorter than the typical dynamical (free fall) one. This allows us to build a large, multi-dimensional multi-species equilibrium abundance table over a large temperature, density and ionisation rate ranges. This table, which we make accessible to the community, is used during first and second prestellar core collapse calculations to compute the non-ideal magneto-hydrodynamics resistivities, yielding a consistent dynamical-chemical description of this process. The multi-dimensional multi-species equilibrium abundance table and a copy of the code are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/592/A18

  9. MHD Turbulence and Magnetic Dynamos

    NASA Technical Reports Server (NTRS)

    Shebalin, John V

    2014-01-01

    Incompressible magnetohydrodynamic (MHD) turbulence and magnetic dynamos, which occur in magnetofluids with large fluid and magnetic Reynolds numbers, will be discussed. When Reynolds numbers are large and energy decays slowly, the distribution of energy with respect to length scale becomes quasi-stationary and MHD turbulence can be described statistically. In the limit of infinite Reynolds numbers, viscosity and resistivity become zero and if these values are used in the MHD equations ab initio, a model system called ideal MHD turbulence results. This model system is typically confined in simple geometries with some form of homogeneous boundary conditions, allowing for velocity and magnetic field to be represented by orthogonal function expansions. One advantage to this is that the coefficients of the expansions form a set of nonlinearly interacting variables whose behavior can be described by equilibrium statistical mechanics, i.e., by a canonical ensemble theory based on the global invariants (energy, cross helicity and magnetic helicity) of ideal MHD turbulence. Another advantage is that truncated expansions provide a finite dynamical system whose time evolution can be numerically simulated to test the predictions of the associated statistical mechanics. If ensemble predictions are the same as time averages, then the system is said to be ergodic; if not, the system is nonergodic. Although it had been implicitly assumed in the early days of ideal MHD statistical theory development that these finite dynamical systems were ergodic, numerical simulations provided sufficient evidence that they were, in fact, nonergodic. Specifically, while canonical ensemble theory predicted that expansion coefficients would be (i) zero-mean random variables with (ii) energy that decreased with length scale, it was found that although (ii) was correct, (i) was not and the expected ergodicity was broken. The exact cause of this broken ergodicity was explained, after much

  10. Chapter 3: MHD stability, operational limits and disruptions

    NASA Astrophysics Data System (ADS)

    Hender, T. C.; Wesley, J. C.; Bialek, J.; Bondeson, A.; Boozer, A. H.; Buttery, R. J.; Garofalo, A.; Goodman, T. P.; Granetz, R. S.; Gribov, Y.; Gruber, O.; Gryaznevich, M.; Giruzzi, G.; Günter, S.; Hayashi, N.; Helander, P.; Hegna, C. C.; Howell, D. F.; Humphreys, D. A.; Huysmans, G. T. A.; Hyatt, A. W.; Isayama, A.; Jardin, S. C.; Kawano, Y.; Kellman, A.; Kessel, C.; Koslowski, H. R.; La Haye, R. J.; Lazzaro, E.; Liu, Y. Q.; Lukash, V.; Manickam, J.; Medvedev, S.; Mertens, V.; Mirnov, S. V.; Nakamura, Y.; Navratil, G.; Okabayashi, M.; Ozeki, T.; Paccagnella, R.; Pautasso, G.; Porcelli, F.; Pustovitov, V. D.; Riccardo, V.; Sato, M.; Sauter, O.; Schaffer, M. J.; Shimada, M.; Sonato, P.; Strait, E. J.; Sugihara, M.; Takechi, M.; Turnbull, A. D.; Westerhof, E.; Whyte, D. G.; Yoshino, R.; Zohm, H.; ITPA MHD, the; Disruption; Magnetic Control Topical Group

    2007-06-01

    Progress in the area of MHD stability and disruptions, since the publication of the 1999 ITER Physics Basis document (1999 Nucl. Fusion 39 2137-2664), is reviewed. Recent theoretical and experimental research has made important advances in both understanding and control of MHD stability in tokamak plasmas. Sawteeth are anticipated in the ITER baseline ELMy H-mode scenario, but the tools exist to avoid or control them through localized current drive or fast ion generation. Active control of other MHD instabilities will most likely be also required in ITER. Extrapolation from existing experiments indicates that stabilization of neoclassical tearing modes by highly localized feedback-controlled current drive should be possible in ITER. Resistive wall modes are a key issue for advanced scenarios, but again, existing experiments indicate that these modes can be stabilized by a combination of plasma rotation and direct feedback control with non-axisymmetric coils. Reduction of error fields is a requirement for avoiding non-rotating magnetic island formation and for maintaining plasma rotation to help stabilize resistive wall modes. Recent experiments have shown the feasibility of reducing error fields to an acceptable level by means of non-axisymmetric coils, possibly controlled by feedback. The MHD stability limits associated with advanced scenarios are becoming well understood theoretically, and can be extended by tailoring of the pressure and current density profiles as well as by other techniques mentioned here. There have been significant advances also in the control of disruptions, most notably by injection of massive quantities of gas, leading to reduced halo current fractions and a larger fraction of the total thermal and magnetic energy dissipated by radiation. These advances in disruption control are supported by the development of means to predict impending disruption, most notably using neural networks. In addition to these advances in means to control or

  11. Model for resistance evolution in shape memory alloys including R-phase

    NASA Astrophysics Data System (ADS)

    Brammajyosula, Ravindra; Buravalla, Vidyashankar; Khandelwal, Ashish

    2011-03-01

    The electrical resistance behavior of a shape memory alloy (SMA) wire can be used for sensing the state of an SMA device. Hence, this study investigates the resistance evolution in SMAs. A lumped parameter model with cosine kinetics to capture the resistance variation during the phase transformation is developed. Several SMA materials show the presence of trigonal or rhombohedral (R) phase as an intermediate phase, apart from the commonly recognized austenite and martensite phases. Most of the SMA models ignore the R-phase effect in their prediction of thermomechanical response. This may be acceptable since the changes in thermomechanical response associated with the R-phase are relatively less. However, the resistivity related effects are pronounced in the presence of the R-phase and its appearance introduces non-monotonicity in the resistivity evolution. This leads to additional complexities in the use of resistance signal for sensing and control. Hence, a lumped model is developed here for resistance evolution including the R-phase effects. A phase-diagram-based model is proposed for predicting electro-thermomechanical response. Both steady state hysteretic response and transient response are modeled. The model predictions are compared with the available test data. Numerical studies have shown that the model is able to capture all the essential features of the resistance evolution in SMAs in the presence of the R-phase.

  12. Anthelmintic Avermectins Kill Mycobacterium tuberculosis, Including Multidrug-Resistant Clinical Strains

    PubMed Central

    Lim, Leah E.; Vilchèze, Catherine; Ng, Carol; Jacobs, William R.; Thompson, Charles J.

    2013-01-01

    Avermectins are a family of macrolides known for their anthelmintic activities and traditionally believed to be inactive against all bacteria. Here we report that members of the family, ivermectin, selamectin, and moxidectin, are bactericidal against mycobacterial species, including multidrug-resistant and extensively drug-resistant clinical strains of Mycobacterium tuberculosis. Avermectins are approved for clinical and veterinary uses and have documented pharmacokinetic and safety profiles. We suggest that avermectins could be repurposed for tuberculosis treatment. PMID:23165468

  13. Magnetic reconnection in a compressible MHD plasma

    SciTech Connect

    Hesse, Michael; Zenitani, Seiji; Birn, Joachim

    2011-04-15

    Using steady-state resistive MHD, magnetic reconnection is reinvestigated for conditions of high resistivity/low magnetic Reynolds number, when the thickness of the diffusion region is no longer small compared to its length. Implicit expressions for the reconnection rate and other reconnection parameters are derived based on the requirements of mass, momentum, and energy conservation. These expressions are solved via simple iterative procedures. Implications specifically for low Reynolds number/high resistivity are being discussed.

  14. Magnetic Reconnection in a Compressible MHD Plasma

    NASA Technical Reports Server (NTRS)

    Hesse, Michael; Birn, Joachim; Zenitani, Seiji

    2011-01-01

    Using steady-state resistive MHD, magnetic reconnection is reinvestigated for conditions of high resistivity/low magnetic Reynolds number, when the thickness of the diffusion region is no longer small compared to its length. Implicit expressions for the reconnection rate and other reconnection parameters are derived based on the requirements of mass, momentum, and energy conservation. These expressions are solved via simple iterative procedures. Implications specifically for low Reynolds number/high resistivity are being discussed

  15. HYBRID AND HALL-MHD SIMULATIONS OF COLLISIONLESS RECONNECTION: EFFECTS OF PLASMA PRESSURE TENSOR

    SciTech Connect

    L. YIN; D. WINSKE; ET AL

    2001-05-01

    In this study we performed two-dimensional hybrid (particle ions, massless fluid electrons) and Hall-MHD simulations of collisionless reconnection in a thin current sheet. Both calculations include the full electron pressure tensor (instead of a localized resistivity) in the generalized Ohm's law to initiate reconnection, and in both an initial perturbation to the Harris equilibrium is applied. First, electron dynamics from the two calculations are compared, and we find overall agreement between the two calculations in both the reconnection rate and the global configuration. To address the issue of how kinetic treatment for the ions affects the reconnection dynamics, we compared the fluid-ion dynamics from the Hall-MHD calculation to the particle-ion dynamics obtained from the hybrid simulation. The comparison demonstrates that off-diagonal elements of the ion pressure tensor are important in correctly modeling the ion out-of-plane momentum transport from the X point. It is that these effects can be modeled efficiently using a particle Hall-MHD simulation method in which particle ions used in a predictor/corrector to implement the ion gyro-radius corrections. We also investigate the micro- macro-scale coupling in the magnetotail dynamics by using a new integrated approach in which particle Hall-MHD calculations are embedded inside a MHD simulation. Initial results of the simulation concerning current sheet thinning and reconnection dynamics are discussed.

  16. Open Boundary Conditions for Dissipative MHD

    SciTech Connect

    Meier, E T

    2011-11-10

    In modeling magnetic confinement, astrophysics, and plasma propulsion, representing the entire physical domain is often difficult or impossible, and artificial, or 'open' boundaries are appropriate. A novel open boundary condition (BC) for dissipative MHD, called Lacuna-based open BC (LOBC), is presented. LOBC, based on the idea of lacuna-based truncation originally presented by V.S. Ryaben'kii and S.V. Tsynkov, provide truncation with low numerical noise and minimal reflections. For hyperbolic systems, characteristic-based BC (CBC) exist for separating the solution into outgoing and incoming parts. In the hyperbolic-parabolic dissipative MHD system, such separation is not possible, and CBC are numerically unstable. LOBC are applied in dissipative MHD test problems including a translating FRC, and coaxial-electrode plasma acceleration. Solution quality is compared to solutions using CBC and zero-normal derivative BC. LOBC are a promising new open BC option for dissipative MHD.

  17. Salient issues of edge physics pertaining to loss of confinement: A resistive MHD analysis. Technical progress report, FY91

    SciTech Connect

    Thayer, D.R.

    1991-12-31

    The progress that has been made during this fiscal year is significant in the area of tokamak edge plasma transport. Important contributions on the extension of the drift-rippling mode model ({approximately} {tau}, {approximately}n, {approximately}T, {approximately}{nu}{sub {parallel}}) of edge turbulent transport. In particular, the research areas on which we have concentrated include the following topics: (1) The theoretical investigation of the radiatively enhanced transport due to the effects of impurity driven radiation instabilities has been expanded to include a situation with multiple impurities (such as carbon, C{sup 4+}, and oxygen, O{sup 6+}); (2) In order to validate the use of the impurity radiation input from the tokamak bolometer experiments in our theoretical edge turbulent transport calculations, the analysis that is utilized to transform impurity brightness data to radiated power profiles has been checked for state population and Abel inversion correctness; (3) The drift-rippling model of edge turbulent transport has been extended to include ionization particle sources in addition to the impurity driven thermal instability drive; and (4) The detailed limiter and realistic edge geometric effects on the edge turbulent transport has been included in the drift-rippling model.

  18. Salient issues of edge physics pertaining to loss of confinement: A resistive MHD analysis. FY91 technical progress report

    SciTech Connect

    Thayer, D.R.

    1991-12-31

    The progress that has been made during this fiscal year is significant in the area of tokamak edge plasma transport. The drift-rippling mode model of edge turbulent transport was extended. In particular, the research areas on which were concentrated include the following topics: (1) The theoretical investigation of the radiatively enhanced transport due to the effects of impurity driven radiation instabilities has been expanded to include a situation with multiple impurities (such as carbon, C{sup 4+}, and oxygen, O{sup 6+}); (2) In order to validate the use of the impurity radiation input from the tokamak bolometer experiments in the theoretical edge turbulent transport calculations, the analysis that is utilized to transform impurity brightness data to radiated power profiles has been checked for state population and Abel inversion correctness; (3) The drift-rippling model of edge turbulent transport has been extended to include ionization particle sources in addition to the impurity driven thermal instability drive; and (4) The detailed limiter and realistic edge geometric effects on the edge turbulent transport has been included in the drift-rippling model.

  19. Finite difference time domain electroacoustic model for synthetic jet actuators including nonlinear flow resistance.

    PubMed

    Kooijman, Gerben; Ouweltjes, Okke

    2009-04-01

    A lumped element electroacoustic model for a synthetic jet actuator is presented. The model includes the nonlinear flow resistance associated with flow separation and employs a finite difference scheme in the time domain. As opposed to more common analytical frequency domain electroacoustic models, in which the nonlinear resistance can only be considered as a constant, it allows the calculation of higher harmonics, i.e., distortion components, generated as a result of this nonlinear resistance. Model calculations for the time-averaged momentum flux of the synthetic jet as well as the radiated sound power spectrum are compared to experimental results for various configurations. It is shown that a significantly improved prediction of the momentum flux-and thus flow velocity-of the jet is obtained when including the nonlinear resistance. Here, the current model performs slightly better than an analytical model. For the power spectrum of radiated sound, a reasonable agreement is obtained when assuming a plausible slight asymmetry in the nonlinear resistance. However, results suggest that loudspeaker nonlinearities play a significant role as well in the generation of the first few higher harmonics.

  20. MHD Flow Control

    DTIC Science & Technology

    2006-09-01

    tested is a model to simulate the hypersonic intake configuration. The corresponding photo is presented in Fig. 49. 75 i I I I I I I Figure 49. The third... hypersonic air stream within the propulsion system inlet. The extra benefit of this proposed Project is the experimental facility to be used for experimental...plasma aerodynamics, and in particular, MHD control of external and internal flows. The MHD control of the external hypersonic flow over the simplest

  1. Urinary tract infections in hospital pediatrics: many previous antibiotherapy and antibiotics resistance, including fluoroquinolones.

    PubMed

    Garraffo, A; Marguet, C; Checoury, A; Boyer, S; Gardrat, A; Houivet, E; Caron, F

    2014-02-01

    We studied antibiotic resistance in pediatric UTIs and we evaluated the impact of antibiotic exposure in the previous 12 months, very little French data being available for this population. We conducted a multicenter prospective study including children consulting for, or admitted in 2 hospitals. Prior antibiotic exposure was documented from their health record. One hundred and ten patients (73 girls), 11 days to 12 years of age, were included in 10 months. Ninety-six percent presented with pyelonephritis, associated to uropathy for 25%. Escherichia coli was predominant (78%), followed by Proteus spp. and Enterococcus spp. The antibiotic resistance rate of E. coli was high and close to that reported for adults with complicated UTIs: amoxicillin 60%, amoxicillin-clavulanate 35%, cefotaxim 5%, trimethoprim-sulfametoxazole 26%, nalidixic acid 9%, ciprofloxacin 7%, gentamycin 1%, nitrofurantoin and fosfomycin 0%. The antibiotic exposure in the previous 12 months involved 62 children (56%) most frequently with β-lactams (89%) for a respiratory tract infection (56%). A clear relationship between exposure and resistance was observed for amoxicillin (71% vs. 46%), first generation (65% vs. 46%) and third generation (9% vs. 3%) cephalosporins, or trimethoprim-sulfamethoxazole (36% vs. 15%). However, antibiotic exposure could not account alone for the results, as suggested by the 7% of ciprofloxacin resistance, observed without any identified previous treatment. Bacterial species and antibiotic resistance level in children are similar to those reported for adults. Antibiotic exposure in the previous 12 months increases the risk of resistance but other factors are involved (previous antibiotic therapies and fecal-oral or mother-to-child transmission). Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  2. Study of extended MHD effects on interchange modes in spheromak equilibria

    NASA Astrophysics Data System (ADS)

    Howell, E. C.; Sovinec, C. R.

    2014-10-01

    A study of extended MHD effects on linear interchange modes is performed using the NIMROD code [Sovinec & King JCP 2010]. A linear cylindrical equilibrium model is adapted from [Jardin NF 1982] to allow finite toroidal current at the edge. These equilibria are representative of SSPX discharges where currents are driven on the open field to keep the safety factor above 1/2 across the profile [McLean et al., POP 2006]. These spheromaks have weak magnetic shear, and interchange stability is an important consideration. The Suydam parameter, D, is scaled to study resistive and ideal interchange modes. The calculated MHD growth rate increases with D. The resistive interchange scaling γ ~η 1 / 3 is observed for D <1/4 . Calculations using the full extended MHD model are performed for a range of hall parameters Λ. This model includes gyro-viscosity, the hall term, equilibrium diamagnetic flows, and the cross-field diamagnetic heat flux. Two fluid effects in the full model are always destabilizing at large Λ. However, some cases exhibit a range of Λ where the growth rate for the full model is reduced relative to the MHD growth rate. Work supported by US DOE.

  3. Vapour-phase activities of essential oils against antibiotic sensitive and resistant bacteria including MRSA.

    PubMed

    Doran, A L; Morden, W E; Dunn, K; Edwards-Jones, V

    2009-04-01

    To determine whether essential oil (EO) vapours could reduce surface and airborne levels of bacteria including methicillin-resistant Staphylococcus aureus (MRSA). The antibacterial activity of geranium and lemongrass EO individually and blended were evaluated over a range of concentrations by direct contact and vapour diffusion. The EO were tested in vitro against a selection of antibiotic-sensitive and -resistant bacteria, including MRSA, vancomycin-resistant Enterococci (VRE), Acinetobacter baumanii and Clostridium difficile. An EO blend containing lemongrass and geranium was used to formulate BioScent that was dispersed into the environment using the ST Pro machine. The effects were variable depending on the methods used. In a sealed box environment, MRSA growth on seeded plates was reduced by 38% after 20 h exposure to BioScent vapour. In an office environment, the ST Pro machine dispersing BioScent effected an 89% reduction of airborne bacteria in 15 h, when operated at a constant output of 100%. EO vapours inhibited growth of antibiotic-sensitive and -resistant bacteria in vitro and reduced surface and airborne levels of bacteria. Results suggest that EO vapours, particularly Bioscent, could be used as a method of air disinfection.

  4. 2-D MHD numerical simulations of EML plasma armatures with ablation

    NASA Astrophysics Data System (ADS)

    Boynton, G. C.; Huerta, M. A.; Thio, Y. C.

    1993-01-01

    We use a 2-D) resistive MHD code to simulate an EML plasma armature. The energy equation includes Ohmic heating, radiation heat transport and the ideal gas equation of state, allowing for variable ionization using the Saha equations. We calculate rail ablation taking into account the flow of heat into the interior of the rails. Our simulations show the development of internal convective flows and secondary arcs. We use an explicit Flux Corrected Transport algorithm to advance all quantities in time.

  5. Simulated selection responses for breeding programs including resistance and resilience to parasites in Creole goats.

    PubMed

    Gunia, M; Phocas, F; Gourdine, J-L; Bijma, P; Mandonnet, N

    2013-02-01

    The Creole goat is a local breed used for meat production in Guadeloupe (French West Indies). As in other tropical countries, improvement of parasite resistance is needed. In this study, we compared predicted selection responses for alternative breeding programs with or without parasite resistance and resilience traits. The overall breeding goal included traits for production, reproduction, and parasite resilience and resistance to ensure a balanced selection outcome. The production traits were BW and dressing percentage (DP). The reproduction trait was fertility (FER), which was the number of doe kiddings per mating. The resistance trait was worm fecal egg count (FEC), which is a measurement of the number of gastro-intestinal parasite eggs found in the feces. The resilience trait was the packed cell volume (PCV), which is a measurement of the volume of red blood cells in the blood. Dressing percentage, BW, and FEC were measured at 11 mo of age, which is the mating or selling age. Fertility and PCV were measured on females at each kidding period. The breeding program accounting for the overall breeding goal and a selection index including all traits gave annual selection responses of 800 g for BW, 3.75% for FER, 0.08% for DP, -0.005 ln(eggs/g) for FEC, and 0.28% for PCV. The expected selection responses for BW and DP in this breeding program were reduced by 2% and 6%, respectively, compared with a breeding program not accounting for FEC and PCV. The overall breeding program, proposed for the Creole breed, offers the best breeding strategy in terms of expected selection responses, making it possible to improve all traits together. It offers a good balance between production and adaptation traits and may present some interest for the selection of other goat breeds in the tropics.

  6. Magnetohydrodynamics (MHD) program evaluation

    SciTech Connect

    Not Available

    1983-05-01

    Conclusions and Recommendations: (1) Progress has been made in performance testing of virtually every critical MHD component and subsystem, except for seed regeneration. (2) No insurmountable technical barriers have been identified; however, the component tests have for the most part been of short duration and, in most instances, were conducted under simulated coal-fired conditions. Long duration, coal-fired integrated tests of the MHD power train and of the HRSR subsystem are required to demonstrate system operability and durability. (3) It would appear most appropriate that the first series of complete power train and HRSR tests be conducted at the 50 MW/sub t/ level. The major objectives of these tests should be to verify predicted performance and to show system operability and durability for a period of at least 2000 hours. (4) Assuming successful 50 MW/sub t/ duration tests, a 150 MW/sub t/ completely integrated (topping and bottoming cycles) utility demonstration test is then suggested (3:1 scale-up). (5) The final development step would involve the fabrication of a commercial size plant at a power level of 500 MW/sub t/ or greater. (6) The ultimate adoption of MHD as a means for electric power generation will not be solely determined by its technical performance; the economic climate and projections at the time the technology is mature will strongly influence utility decisions. (7) Estimated capital costs of early commercial MHD plants seem to range from 10% to 30% greater than those for PCF plants with scrubbers. However, because of the higher inherent efficiency of MHD relative to PCF plants (50% vs 35%), the cost of electric power (COE) from an MHD system can nevertheless be competitive for an appropriately broad range of economic scenarios. (8) Finally, it is recognized that a major investment will be necessary to bring the technology to a state of commercial readiness.

  7. Computation of the MHD modes with rotation and kinetic effects: AEGIS

    NASA Astrophysics Data System (ADS)

    Zheng, L.-J.; Kotschenreuther, M.; Turnbull, A.; Waelbroeck, F.; van Dam, J. W.; Berk, H.

    2003-10-01

    A new linear MHD eigenvalue code called AEGIS (Adaptive EiGenfunction Independent Shooting) is being developed at the IFS. The benchmarking of AEGIS with GATO is underway and will be presented. Plasma rotation is being included, with the effect of rotation-enhanced plasma compressibility also taken into account. As a first step in including rotational effects, the ideal MHD model is being employed. Details of the numerical scheme will be described, along with preliminary numerical results. The plan to include kinetic compressiblity will be discussed. With this new code, rotational stabilization of resistive wall modes can be rigorously calculated for the first time. The algorithm also allows FLR effects to be included. Many helpful suggestions from A. Glasser are acknowledged.

  8. Drug-resistant tuberculosis in subjects included in the Second National Survey on Antituberculosis Drug Resistance in Porto Alegre, Brazil*, **

    PubMed Central

    Micheletti, Vania Celina Dezoti; Moreira, José da Silva; Ribeiro, Marta Osório; Kritski, Afranio Lineu; Braga, José Ueleres

    2014-01-01

    OBJECTIVE: To describe the prevalence of multidrug-resistant tuberculosis (MDR-TB) among tuberculosis patients in a major Brazilian city, evaluated via the Second National Survey on Antituberculosis Drug Resistance, as well as the social, demographic, and clinical characteristics of those patients. METHODS: Clinical samples were collected from tuberculosis patients seen between 2006 to 2007 at three hospitals and five primary health care clinics participating in the survey in the city of Porto Alegre, Brazil. The samples were subjected to drug susceptibility testing. The species of mycobacteria was confirmed using biochemical methods. RESULTS: Of the 299 patients included, 221 (73.9%) were men and 77 (27.3%) had a history of tuberculosis. The mean age was 36 years. Of the 252 patients who underwent HIV testing, 66 (26.2%) tested positive. The prevalence of MDR-TB in the sample as a whole was 4.7% (95% CI: 2.3-7.1), whereas it was 2.2% (95% CI: 0.3-4.2) among the new cases of tuberculosis and 12.0% (95% CI: 4.5-19.5) among the patients with a history of tuberculosis treatment. The multivariate analysis showed that a history of tuberculosis and a longer time to diagnosis were both associated with MDR-TB. CONCLUSIONS: If our results are corroborated by other studies conducted in Brazil, a history of tuberculosis treatment and a longer time to diagnosis could be used as predictors of MDR-TB. PMID:24831400

  9. Disk MHD generator study

    NASA Technical Reports Server (NTRS)

    Retallick, F. D.

    1980-01-01

    Directly-fired, separately-fired, and oxygen-augmented MHD power plants incorporating a disk geometry for the MHD generator were studied. The base parameters defined for four near-optimum-performance MHD steam power systems of various types are presented. The finally selected systems consisted of (1) two directly fired cases, one at 1920 K (2996F) preheat and the other at 1650 K (2500 F) preheat, (2) a separately-fired case where the air is preheated to the same level as the higher temperature directly-fired cases, and (3) an oxygen augmented case with the same generator inlet temperature of 2839 (4650F) as the high temperature directly-fired and separately-fired cases. Supersonic Mach numbers at the generator inlet, gas inlet swirl, and constant Hall field operation were specified based on disk generator optimization. System pressures were based on optimization of MHD net power. Supercritical reheat stream plants were used in all cases. Open and closed cycle component costs are summarized and compared.

  10. Line-tied MHD modes: effect of plasma pressure, axial boundary condition and axial flow

    NASA Astrophysics Data System (ADS)

    Arcudi, Francesco; Delzanno, Gian Luca; Finn, John M.

    2008-11-01

    Recent 3D nonlinear magnetohydrodynamic (MHD) simulations of astrophysical jets [1] showed a narrow jet-like region with very tightly wound magnetic fields, very suggestive of jet observations. These results were unexpected because such tightly wound magnetic fields should be violently MHD unstable. In order to make direct contact with the simulations of Ref. [1], we present a linear stability study in resistive MHD in cylindrical geometry. In this work, stability is studied including axial flows and finite plasma pressure. We also changed the axial boundary conditions to model those typical of astrophysical jets and laboratory experiments, using line-tying at one end of the field lines and non-line-tied boundary conditions at the other end [2]. The numerical results show that pressure strongly shifts the marginal stability threshold relative to the Kruskal-Shafranov threshold and a monotonically increasing pressure profile stabilizes the plasma. On the other hand, non-line-tied boundary conditions have little effect on marginal stability for typical parameters. All the results are supported by analytical studies based on reduced ideal MHD. [1] H. Li, G. Lapenta, J. M. Finn, S. Li, and S. A. Colgate, Astrophys. J. 643, 92 (2006). [2] D. D. Ryutov, I. Furno, T. P. Intrator, S. Abbate, and T. Madziwa-Nussinov, Phys. Plasmas 13, 032105 (2006).

  11. MHD Equation of State with Relativistic Electrons

    NASA Astrophysics Data System (ADS)

    Gong, Zhigang; Däppen, Werner; Zejda, Ladislav

    2001-01-01

    The Mihalas-Däppen-Hummer (MHD) equation of state does not include the effect of relativistic partially degenerate electrons, although nonrelativistic partial degeneracy is taken into account. The discovery of a relativistic correction in helioseismology forces us to perform an appropriate upgrade of the MHD equation of state. We have adopted the method of J. M. Aparicio to evaluate the relativistic Fermi-Dirac functions. Our calculations confirm the validity of the approximation used, which works well for the weakly relativistic electrons under solar-center conditions. However, our results will also provide reliable thermodynamic quantities in the stronger relativistic regime as found in more massive stars. Since a particular feature of the original MHD papers was an explicit list of the adopted free energy and its first- and second-order analytical derivatives, we give the corresponding relativistic quantities in the Appendix.

  12. Analytical estimates of turbulent MHD transport coefficients

    NASA Technical Reports Server (NTRS)

    Montgomery, D.; Hatori, T.

    1984-01-01

    Turbulent transfer rates from small-scale MHD excitations to large-scale Fourier modes are calculated algebraically, using the method of Biskamp and Welter. Three cases are considered: two-dimensional Navier-Stokes flows, two-dimensional incompressible MHD, and the weakly three-dimensional Strauss equations. In all cases, an initially large spectral gap between the small-scale and large-scale excitations is assumed, and attention focusses on the initial values of the back-transfer rates. The sign of the transfer is determined by the sign of an analytically calculable eddy viscosity and/or anomalous resistivity. We are able to confirm the results of Biskamp and Welter for the case of two-dimensional MHD, but find some differences for the case of the Strauss equations. It is argued that the Strauss equations may not exhibit an inverse cascade phenomenon for the spatially periodic case unless their initial spectra are such that the behavior is essentially that of two-dimensional MHD.

  13. MHD simulations: Corotating Interaction Regions

    NASA Astrophysics Data System (ADS)

    Wiengarten, T.; Kleimann, J.; Fichtner, H.; Kühl, P.; Heber, B.; Kissmann, R.

    2013-12-01

    Corotating Interaction Regions (CIRs) form in the solar wind when parcels of fast-speed wind interact with slow-speed wind due to the rotation of the Sun. The resulting buildup of pressure generates disturbances that, with increasing time (or distance from the Sun), may develop into a so-called forward-reverse shock-pair. During solar-quiet times CIRs can be the dominant force shaping large-scale structures in the heliosphere. Studying CIRs is therefore important because the associated shocks are capable of e.g. accelerating energetic particles or deflecting cosmic rays. The global structure of CIRs can be modeled with an MHD approach that gives the plasma quantities needed to model the transport of particles in the heliosphere (with e.g. stochastic differential equations (SDEs)). Our MHD code CRONOS employs a semi-discrete finite volume scheme with adaptive time-stepping Runge-Kutta integration. The solenoidality of the magnetic field is ensured via constrained transport and the code supports Cartesian, Cylindrical and Spherical coordinates (including coordinate singularities) with the option for non-equidistant grids. The code runs in parallel (MPI) and supports the HDF5 output data format. Here, we show results from 3D-MHD simulations with our code CRONOS for a) analytic boundary conditions where results can be compared to those obtained with a different code and b) boundary conditions derived with the Wang-Sheeley-Arge model from observational data (WSO), which are compared to spacecraft observations. Comparison with Pizzo (1982) for analytic boundary conditions Comparison with STEREO A for Carrington Rotation 2060

  14. Analytic expression for the Fowler-Nordheim V- I characteristic including the series resistance effect

    NASA Astrophysics Data System (ADS)

    Miranda, E.; Palumbo, F.

    2011-07-01

    It is shown in this communication that the Fowler-Nordheim (FN) tunneling expression for the current-voltage ( I- V) characteristic can be analytically inverted so that an exact expression for the voltage-current ( V- I) characteristic can be obtained. The solution of the resulting implicit equation is found using the Lambert W function, i.e. the solution of the transcendental equation we w = x. The reported expressions are supported by experimental I- V curves measured in thin (≈5 nm) SiO 2 films in MOS capacitors. The analysis includes the case of a tunneling oxide with a large series resistance. For practical purposes, a closed-form expression for W based on a Padé-type approximation is also provided.

  15. Antimicrobial prescribing patterns for respiratory diseases including tuberculosis in Russia: a possible role in drug resistance?

    PubMed

    Balabanova, Yanina; Fedorin, Ivan; Kuznetsov, Sergey; Graham, Catriona; Ruddy, Michael; Atun, Rifat; Coker, Richard; Drobniewski, Francis

    2004-09-01

    Inappropriate antibiotic prescribing exposes patients to the risk of side effects and encourages the development of drug resistance across antimicrobial groups used for respiratory infections including tuberculosis (TB). Determine among Russian general practitioners and specialists: (1) sources of antimicrobial prescribing information; (2) patterns of antimicrobial prescribing for common respiratory diseases and differences between primary and specialist physicians; (3) whether drug resistance in TB might be linked to over-prescribing of anti-TB drugs for respiratory conditions. Point-prevalence cross-sectional survey involving all 28 primary care, general medicine and TB treatment institutions in Samara City, Russian Federation. In this two-stage study, a questionnaire was used to examine doctors' antimicrobial (including TB drugs) prescribing habits, sources of prescribing information, management of respiratory infections and a case scenario ('common cold'). This was followed by a case note review of actual prescribing for consecutive patients with respiratory diseases at three institutions. Initial questionnaires were completed by 81.3% (425/523) of physicians with 78.4% working in primary care. Most doctors used standard textbooks to guide their antimicrobial practice but 80% made extensive use of pharmaceutical company information. A minority of 1.7% would have inappropriately prescribed antibiotics for the case and 0.8-1.8% of respondents would have definitely prescribed TB drugs for non-TB conditions. Of the 495 respiratory cases, 25% of doctors prescribed an antibiotic for a simple upper respiratory tract infection and of 8 patients with a clinical diagnosis of TB, 4 received rifampicin monotherapy alone. Ciprofloxacin was widely but inappropriately used. Doctors rely on information provided by pharmaceutical companies; there was inappropriate antibiotic prescribing.

  16. Classical MHD shocks: theory and numerical simulation

    SciTech Connect

    Pogorelov, Nikolai V.

    2005-08-01

    Recent results are surveyed in the investigation of the behavior of shocks in ideal magnetohydrodynamics (MHD) and corresponding structures in dissipative/resistive plasma flows. In contrast to evolutionary shocks, a solution of the problem of the nonevolutionary shock interaction with small perturbations is either nonunique or does not exist. The peculiarity of non-ideal MHD is in that some nonevolutionary shocks have dissipative structures. Since this structure is always non-plane, it can reveal itself in problems where transverse perturbations do not exist due to symmetries restrictions. We discuss the numerical behavior of nonevolutionary shocks and argue that they necessarily disappear once the problem is solved in a genuinely three-dimensional statement.

  17. Hospital Isolates of Serratia marcescens Transferring Ampicillin, Carbenicillin, and Gentamicin Resistance to Other Gram-Negative Bacteria Including Pseudomonas aeruginosa

    PubMed Central

    Olexy, Vera M.; Bird, Thomas J.; Grieble, Hans G.; Farrand, Stephen K.

    1979-01-01

    Thirteen independent isolates of Serratia marcescens associated with nosocomial urinary tract infections were obtained from the clinical microbiology laboratory at Hines Veterans Administration Hospital. The isolates were resistant to at least ampicillin, carbenicillin, gentamicin, and tobramycin. They could be divided into two groups on the basis of their antibiotypes. Group I (9 strains) showed resistance to 13 antibiotics, including 3 beta-lactams, 6 aminoglycosides, tetracycline, sulfonamide, trimethoprim, and polymyxin B. Group II (4 strains) was resistant to 11 antibiotics, including 3 beta-lactams, 5 aminoglycosides, sulfonamide, trimethoprim, and polymyxin B. Donors from both groups transferred resistance traits to Escherichia coli. Transconjugants from matings with group II donors all acquired resistance to nine antibiotics, including the three beta-lactams, five aminoglycosides, and sulfonamide. Transconjugants from matings with group I donors were of varied antibiotypes, inheriting resistance to up to 11 of the 13 antibiotics. Resistances to trimethoprim and polymyxin B were never observed to transfer. E. coli transconjugants of each group were capable of transferring multiple-antibiotic resistance to several other members of the family Enterobacteriaceae. All group II S. marcescens and E. coli donors and all group I S. marcescens donors transferred carbenicillin, streptomycin, kanamycin, gentamicin, tobramycin, and sisomicin resistance to Pseudomonas aeruginosa. The results suggest that these S. marcescens strains harbor R factors of a broader host range than previously reported. PMID:106772

  18. The role of kinetic effects, including plasma rotation and energetic particles, in resistive wall mode stability

    SciTech Connect

    Berkery, J. W.; Sabbagh, S. A.; Reimerdes, H.; Betti, R.; Hu, B.; Bell, R. E.; Gerhardt, S. P.; Manickam, J.; Podesta, M.

    2010-08-15

    The resistive wall mode (RWM) instability in high-beta tokamaks is stabilized by energy dissipation mechanisms that depend on plasma rotation and kinetic effects. Kinetic modification of ideal stability calculated with the 'MISK' code [B. Hu et al., Phys. Plasmas 12, 057301 (2005)] is outlined. For an advanced scenario ITER [R. Aymar et al., Nucl. Fusion 41, 1301 (2001)] plasma, the present calculation finds that alpha particles are required for RWM stability at presently expected levels of plasma rotation. Kinetic stabilization theory is tested in an experiment in the National Spherical Torus Experiment (NSTX) [M. Ono et al., Nucl. Fusion 40, 557 (2000)] that produced marginally stable plasmas with various energetic particle contents. Plasmas with the highest and lowest energetic particle content agree with calculations predicting that increased energetic particle pressure is stabilizing but does not alter the nonmonotonic dependence of stability on plasma rotation due to thermal particle resonances. Presently, the full MISK model, including thermal particles and an isotropic slowing-down distribution function for energetic particles, overpredicts stability in NSTX experiments. Minor alteration of either effect in the theory may yield agreement; several possibilities are discussed.

  19. Cosmological AMR MHD with Enzo

    SciTech Connect

    Xu, Hao; Li, Hui; Li, Shengtai

    2009-01-01

    In this work, we present EnzoMHD, the extension of the cosmological code Enzoto include magnetic fields. We use the hyperbolic solver of Li et al. (2008) for the computation of interface fluxes. We use constrained transport methods of Balsara & Spicer (1999) and Gardiner & Stone (2005) to advance the induction equation, the reconstruction technique of Balsara (2001) to extend the Adaptive Mesh Refinement of Berger & Colella (1989) already used in Enzo, though formulated in a slightly different way for ease of implementation. This combination of methods preserves the divergence of the magnetic field to machine precision. We use operator splitting to include gravity and cosmological expansion. We then present a series of cosmological and non cosmologjcal tests problems to demonstrate the quality of solution resulting from this combination of solvers.

  20. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-07-01

    This seventeenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period August 1, 1991 to October 31, 1991. Manufacturing of the prototypical combustor pressure shell has been completed including leak, proof, and assembly fit checking. Manufacturing of forty-five cooling panels was also completed including leak, proof, and flow testing. All precombustor internal components (combustion can baffle and swirl box) were received and checked, and integration of the components was initiated. A decision was made regarding the primary and backup designs for the 1A4 channel. The assembly of the channel related prototypical hardware continued. The cathode wall electrical wiring is now complete. The mechanical design of the diffuser has been completed.

  1. MHD Wave Modes Resolved in Fine-Scale Chromospheric Magnetic Structures

    NASA Astrophysics Data System (ADS)

    Verth, G.; Jess, D. B.

    2016-02-01

    Due to its complex and dynamic fine-scale structure, the chromosphere is a particularly challenging region of the Sun's atmosphere to understand. It is now widely accepted that to model chromospheric dynamics, even on a magnetohydrodynamic (MHD) scale, while also calculating spectral line emission, one must realistically include the effects of partial ionization and radiative transfer in a multi-fluid plasma under non-LTE conditions. Accurate quantification of MHD wave energetics must be founded on a precise identification of the actual wave mode being observed. This chapter focuses on MHD kink-mode identification, MHD sausage mode identification, and MHD torsional Alfvén wave identification. It then reviews progress in determining more accurate energy flux estimations of specific MHD wave modes observed in the chromosphere. The chapter finally examines how the discovery of these MHD wave modes has helped us advance the field of chromospheric magnetoseismology.

  2. Fully Parallel MHD Stability Analysis Tool

    NASA Astrophysics Data System (ADS)

    Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang

    2015-11-01

    Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Results of MARS parallelization and of the development of a new fix boundary equilibrium code adapted for MARS input will be reported. Work is supported by the U.S. DOE SBIR program.

  3. Fully Parallel MHD Stability Analysis Tool

    NASA Astrophysics Data System (ADS)

    Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang

    2014-10-01

    Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Initial results of the code parallelization will be reported. Work is supported by the U.S. DOE SBIR program.

  4. Fully Parallel MHD Stability Analysis Tool

    NASA Astrophysics Data System (ADS)

    Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang

    2013-10-01

    Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Preliminary results of the code parallelization will be reported. Work is supported by the U.S. DOE SBIR program.

  5. Open boundary conditions for dissipative MHD

    NASA Astrophysics Data System (ADS)

    Meier, Eric; Glasser, Alan; Lukin, Vyacheslav; Shumlak, Uri; PSI-Center Collaboration

    2011-10-01

    In modeling magnetic confinement, astrophysics, and plasma propulsion, representing the entire physical domain is often difficult or impossible, and artificial, or ``open'' boundaries are appropriate. A novel open boundary condition (BC) for dissipative MHD, called Lacuna-based open BC (LOBC), is presented. LOBC, based on the idea of lacuna-based truncation originally presented by V.S. Ryaben'kii and S.V. Tsynkov, provide truncation with low numerical noise and minimal reflections. For hyperbolic systems, characteristic-based BC (CBC) exist for separating the solution into outgoing and incoming parts. In the hyperbolic-parabolic dissipative MHD system, such separation is not possible, and CBC are numerically unstable. LOBC are applied in dissipative MHD test problems including a translating FRC, and coaxial-electrode plasma acceleration. Solution quality is compared to solutions using CBC and zero-normal derivative BC. LOBC are a promising new open BC option for dissipative MHD. Supported by DOE grant DE-FC02-05ER54811.

  6. Isolation of Clostridium difficile from dogs with digestive disorders, including stable metronidazole-resistant strains.

    PubMed

    Orden, Cristina; Blanco, Jose L; Álvarez-Pérez, Sergio; Garcia-Sancho, Mercedes; Rodriguez-Franco, Fernando; Sainz, Angel; Villaescusa, Alejandra; Harmanus, Celine; Kuijper, Ed; Garcia, Marta E

    2017-02-01

    The prevalence of Clostridium difficile in 107 dogs with diverse digestive disorders attended in a Spanish veterinary teaching hospital was assessed. The microorganism was isolated from 13 dogs (12.1%) of different disease groups. Isolates belonged to PCR ribotypes 078, 106, 154 and 430 (all of them toxigenic) and 110 (non-toxigenic), and were resistant to several antimicrobial drugs. Notably, seven isolates obtained from different dogs displayed stable resistance to metronidazole. The results of this study provide further evidence that dogs can act as a reservoir of C. difficile strains of epidemic ribotypes with resistance to multiple antibiotics.

  7. Broken Ergodicity in MHD Turbulence in a Spherical Domain

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.; wang, Yifan

    2011-01-01

    Broken ergodicity (BE) occurs in Fourier method numerical simulations of ideal, homogeneous, incompressible magnetohydrodynamic (MHD) turbulence. Although naive statistical theory predicts that Fourier coefficients of fluid velocity and magnetic field are zero-mean random variables, numerical simulations clearly show that low-wave-number coefficients have non-zero mean values that can be very large compared to the associated standard deviation. In other words, large-scale coherent structure (i.e., broken ergodicity) in homogeneous MHD turbulence can spontaneously grow out of random initial conditions. Eigenanalysis of the modal covariance matrices in the probability density functions of ideal statistical theory leads to a theoretical explanation of observed BE in homogeneous MHD turbulence. Since dissipation is minimal at the largest scales, BE is also relevant for resistive magnetofluids, as evidenced in numerical simulations. Here, we move beyond model magnetofluids confined by periodic boxes to examine BE in rotating magnetofluids in spherical domains using spherical harmonic expansions along with suitable boundary conditions. We present theoretical results for 3-D and 2-D spherical models and also present computational results from dynamical simulations of 2-D MHD turbulence on a rotating spherical surface. MHD turbulence on a 2-D sphere is affected by Coriolus forces, while MHD turbulence on a 2-D plane is not, so that 2-D spherical models are a useful (and simpler) intermediate stage on the path to understanding the much more complex 3-D spherical case.

  8. Synergy of Penicillin-Netilmicin Combinations Against Enterococci Including Strains Highly Resistant to Streptomycin or Kanamycin

    PubMed Central

    Sanders, Christine C.

    1977-01-01

    The in vitro activity of combinations of penicillin and netilimicin was determined against 20 clinical isolates of enterococci and compared with that obtained in simultaneous tests with penicillin/sisomicin, penicillin/streptomycin, and penicillin/kanamycin. Synergy between the two drugs in each combination was determined by the use of quantitative kill curves and was defined as a killing by the combination at least 100-fold greater than that produced by the most effective drug alone. Penicillin/netilmicin and penicillin/sisomicin combinations were found to be synergistic against the majority of isolates tested, including strains resistant to penicillin/streptomycin or penicillin/kanamycin combinations. This synergy with penicillin could be demonstrated at a concentration of ≤7 μg/ml for either netilmicin or sisomicin. Studies on the kinetics of killing produced by these combinations showed the rate and extent of killing to be directly dependent upon the organism's relative susceptibility to the aminoglycoside alone and the aminoglycoside concentration in the combination. Results also indicated that the interaction between penicillin and netilmicin was true synergy; i.e., rapid and complete killing was produced by combinations containing each drug at concentrations insufficient to produce any killing alone, and the killing observed could not be produced by either drug alone at a concentration equivalent to the total drug concentration in the combination. The potential clinical application of this synergistic interaction should be investigated further, especially in view of recent reports showing netilmicin to be considerably less toxic than gentamicin in experimental animals. PMID:242509

  9. EDITORIAL: 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control

    NASA Astrophysics Data System (ADS)

    Buttery, Richard

    2011-08-01

    This annual workshop on MHD Stability Control has been held since 1996 with a focus on understanding and developing control of MHD instabilities for future fusion reactors. The workshop generally covers a wide range of stability topics: from disruptions, to tearing modes, error fields, ELMs, resistive wall modes (RWMs) and ideal MHD. It spans many device types, particularly tokamaks, stellarators and reversed field pinches, to pull out commonalities in the physics and improve understanding. In 2010 the workshop was held on 15-17 November at the University of Wisconsin in Madison and was combined with the annual US-Japan MHD Workshop. The theme was `3D Magnetic Field Effects in MHD Control', with a focus on multidisciplinary sessions exploring issues of plasma response to 3D fields, the manifestation of such fields in the plasma, and how they influence stability. This has been a topic of renewed interest, with utilisation of 3D fields for ELM control now planned in ITER, and a focus on the application of such fields for error field correction, disruption avoidance, and RWM control. Key issues included the physics of the interaction, types of coils and harmonic spectra needed to control instabilities, and subsidiary effects such as braking (or rotating) the plasma. More generally, a wider range of issues were discussed including RWM physics, tearing mode physics, disruption mitigation, ballooning stability, the snowflake divertor concept, and the line tied pinch! A novel innovation to the meeting was a panel discussion session, this year on Neoclassical Toroidal Viscosity, which ran well; more will be tried next year. In this special section of Plasma Physics and Controlled Fusion we present several of the invited and contributed papers from the 2010 workshop, which have been subject to the normal refereeing procedures of the journal. These papers give a sense of the exceptional quality of the presentations at this workshop, all of which may be found at http://fusion.gat.com/conferences/mhd

  10. Activity of gemifloxacin tested against Neisseria gonorrhoeae isolates including antimicrobial-resistant phenotypes.

    PubMed

    Pottumarthy, Sudha; Fritsche, Thomas R; Jones, Ronald N

    2006-02-01

    The antigonococcal potency of gemifloxacin and 5 reference comparator antimicrobials was determined for a selected collection of gonococcal isolates. The 250 Neisseria gonorrhoeae strains were inclusive of (1) 50 historic strains from Japan with elevated fluoroquinolone minimal inhibitory concentration values (QRNG) and (2) 200 contemporary strains from clinical specimens in 2004 (176 from 6 sentinel sites in the United States and 24 bacteremic isolates from the SENTRY Antimicrobial Surveillance Program). The rank order of potency of the tested antimicrobials for the entire collection was: ceftriaxone (MIC(90) = 0.06 microg/mL) > gemifloxacin (1 microg/mL) > tetracycline (2 microg/mL) > ciprofloxacin = levofloxacin = penicillin (4 microg/mL). The activity of gemifloxacin was not affected by penicillinase production; however, its activity was decreased for penicillin-resistant strains. Cross-resistance between gemifloxacin and the older fluoroquinolones was present, and the gemifloxacin MIC90 value was higher for the ciprofloxacin-resistant strains compared with the ciprofloxacin-susceptible strains (2 versus 0.016 mug/mL, respectively). More than 20.0% of the recent clinical strains were resistant to penicillin, tetracycline, and ciprofloxacin with >30.0% of gonococci resistant to ciprofloxacin in Washington State and Hawaii. The historic QRNG strains from the Far East were predominantly of intermediate susceptibility (88.0%) to ciprofloxacin, with a gemifloxacin MIC90 value of only 0.25 microg/mL. The bacteremic gonococcal strains were exquisitely susceptible to the 3 quinolones tested (ciprofloxacin, levofloxacin, and gemifloxacin, MIC90 at < or = 0.03 microg/mL) and ceftriaxone (MIC90 = 0.06 microg/mL). In summary, the potency of gemifloxacin was competitive and positioned between that of ceftriaxone and older quinolones or penicillin or tetracycline, irrespective of the gonococcal resistance phenotype. Gemifloxacin should be considered for further development

  11. Advances in the theory and application of BSF cells. [including electrical resistivity and photovoltaic cells

    NASA Technical Reports Server (NTRS)

    Mandelkorn, J.; Lamneck, J. H.

    1975-01-01

    The characteristics and behavior of p(+), p solar cells were investigated. The p(+), p cells were made by the removal of the n(+) surface layers from n(+), p p(+), BSF cells followed by application of a suitable contact to the resultant p(+), p structures. The open circuit voltage of p(+), p cells was found to increase with increasing 'p' bulk resistivity. The measured open circuit velocity-temperature coefficients were positive and increased with increasing resistivity. An outline of prior limitations in solar cell design is presented, and the removal of these limitations through use of BSF effects is pointed out. The study of BSF effects made feasible production of very thin high efficiency silicon cells as well as high resistivity-high efficiency cells, two desirable types of silicon cells which were previously impossible to make.

  12. MHD thrust vectoring of a rocket engine

    NASA Astrophysics Data System (ADS)

    Labaune, Julien; Packan, Denis; Tholin, Fabien; Chemartin, Laurent; Stillace, Thierry; Masson, Frederic

    2016-09-01

    In this work, the possibility to use MagnetoHydroDynamics (MHD) to vectorize the thrust of a solid propellant rocket engine exhaust is investigated. Using a magnetic field for vectoring offers a mass gain and a reusability advantage compared to standard gimbaled, elastomer-joint systems. Analytical and numerical models were used to evaluate the flow deviation with a 1 Tesla magnetic field inside the nozzle. The fluid flow in the resistive MHD approximation is calculated using the KRONOS code from ONERA, coupling the hypersonic CFD platform CEDRE and the electrical code SATURNE from EDF. A critical parameter of these simulations is the electrical conductivity, which was evaluated using a set of equilibrium calculations with 25 species. Two models were used: local thermodynamic equilibrium and frozen flow. In both cases, chlorine captures a large fraction of free electrons, limiting the electrical conductivity to a value inadequate for thrust vectoring applications. However, when using chlorine-free propergols with 1% in mass of alkali, an MHD thrust vectoring of several degrees was obtained.

  13. Improvement of Scratch and Wear Resistance of Polymers by Fillers Including Nanofillers

    PubMed Central

    Brostow, Witold; Lobland, Haley E. Hagg; Hnatchuk, Nathalie; Perez, Jose M.

    2017-01-01

    Polymers have lower resistance to scratching and wear than metals. Liquid lubricants work well for metals but not for polymers nor for polymer-based composites (PBCs). We review approaches for improvement of tribological properties of polymers based on inclusion of fillers. The fillers can be metallic or ceramic—with obvious consequences for electrical resistivity of the composites. Distinctions between effectiveness of micro- versus nano-particles are analyzed. For example, aluminum nanoparticles as filler are more effective for property improvement than microparticles at the same overall volumetric concentration. Prevention of local agglomeration of filler particles is discussed along with a technique to verify the prevention. PMID:28336900

  14. Improvement of Scratch and Wear Resistance of Polymers by Fillers Including Nanofillers.

    PubMed

    Brostow, Witold; Lobland, Haley E Hagg; Hnatchuk, Nathalie; Perez, Jose M

    2017-03-16

    Polymers have lower resistance to scratching and wear than metals. Liquid lubricants work well for metals but not for polymers nor for polymer-based composites (PBCs). We review approaches for improvement of tribological properties of polymers based on inclusion of fillers. The fillers can be metallic or ceramic-with obvious consequences for electrical resistivity of the composites. Distinctions between effectiveness of micro- versus nano-particles are analyzed. For example, aluminum nanoparticles as filler are more effective for property improvement than microparticles at the same overall volumetric concentration. Prevention of local agglomeration of filler particles is discussed along with a technique to verify the prevention.

  15. Conceptual design of the MHD Engineering Test Facility

    NASA Technical Reports Server (NTRS)

    Bents, D. J.; Bercaw, R. W.; Burkhart, J. A.; Mroz, T. S.; Rigo, H. S.; Pearson, C. V.; Warinner, D. K.; Hatch, A. M.; Borden, M.; Giza, D. A.

    1981-01-01

    The reference conceptual design of the MHD engineering test facility, a prototype 200 MWe coal-fired electric generating plant designed to demonstrate the commerical feasibility of open cycle MHD is summarized. Main elements of the design are identified and explained, and the rationale behind them is reviewed. Major systems and plant facilities are listed and discussed. Construction cost and schedule estimates are included and the engineering issues that should be reexamined are identified.

  16. Conceptual design of the MHD Engineering Test Facility

    NASA Astrophysics Data System (ADS)

    Bents, D. J.; Bercaw, R. W.; Burkhart, J. A.; Mroz, T. S.; Rigo, H. S.; Pearson, C. V.; Warinner, D. K.; Hatch, A. M.; Borden, M.; Giza, D. A.

    The reference conceptual design of the MHD engineering test facility, a prototype 200 MWe coal-fired electric generating plant designed to demonstrate the commerical feasibility of open cycle MHD is summarized. Main elements of the design are identified and explained, and the rationale behind them is reviewed. Major systems and plant facilities are listed and discussed. Construction cost and schedule estimates are included and the engineering issues that should be reexamined are identified.

  17. Multiplex characterization of human pathogens including species and antibiotic-resistance gene identification.

    PubMed

    Barisˇ ić, Ivan; Petzka, Josefine; Schoenthaler, Silvia; Vierlinger, Klemens; Noehammer, Christa; Wiesinger-Mayr, Herbert

    2016-01-01

    The efficient medical treatment of infections requires detailed information about the pathogens involved and potential antibiotic-resistance mechanisms. The dramatically increasing incidence of multidrug-resistant bacteria especially highlights the importance of sophisticated diagnostic tests enabling a fast patient-customized therapy. However, the current molecular detection methods are limited to either the detection of species or only a few antibiotic-resistance genes.In this work, we present a human pathogen characterization assay using a rRNA gene microarray identifying 75 species comprising bacteria and fungi. A statistical classifier was developed to facilitate the automated species identification. Additionally, the clinically most important β-lactamases were identified simultaneously in a 100-plex reaction using padlock probes and the same microarray. The specificity and sensitivity of the combined assay was determined using clinical isolates. The detection limit was 10(5) c.f.u. ml(-1), recovering 89 % of the detectable β-lactamase-encoding genes specifically. The total assay time was less than 7 hand the modular character of the antibiotic-resistance detection allows the easy integration of further genetic targets. In summary, we present a fast, highly specific and sensitive multiplex pathogen characterization assay.

  18. Specific balance training included in an endurance-resistance exercise program improves postural balance in elderly patients undergoing haemodialysis.

    PubMed

    Frih, Bechir; Mkacher, Wajdi; Jaafar, Hamdi; Frih, Ameur; Ben Salah, Zohra; El May, Mezry; Hammami, Mohamed

    2017-01-13

    The purpose of this study was to evaluate the effects of 6 months of specific balance training included in endurance-resistance program on postural balance in haemodialysis (HD) patients. Forty-nine male patients undergoing HD were randomly assigned to an intervention group (balance training included in an endurance-resistance training, n = 26) or a control group (resistance-endurance training only, n = 23). Postural control was assessed using six clinical tests; Timed Up and Go test, Tinetti Mobility Test, Berg Balance Scale, Unipodal Stance test, Mini-Balance Evaluation Systems Test and Activities Balance Confidence scale. All balance measures increased significantly after the period of rehabilitation training in the intervention group. Only the Timed Up and Go, Berg Balance Scale, Mini-Balance Evaluation Systems Test and Activities Balance Confidence scores were improved in the control group. The ranges of change in these tests were greater in the balance training group. In HD patients, specific balance training included in a usual endurance-resistance training program improves static and dynamic balance better than endurance-resistance training only. Implications for rehabilitation Rehabilitation using exercise in haemodialysis patients improved global mobility and functional abilities. Specific balance training included in usual endurance resistance training program could lead to improved static and dynamic balance.

  19. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-02-01

    A summary of the work is excerpted here. Final design of an MHD channel for the ITC program POC test has been completed. The channel was designed to be capable of 1.5 MW {sub e} power output and a lifetime of 2000 hours. Emphasis was placed upon durability and reliability. Hence, specific measures were taken to design against channel damage due to electric faults. The life-limiting issues associated with electrochemical corrosion and erosion of gas-side surfaces were addressed by the use of various materials with proven wear characteristics in a coal-fired MHD channel environment. Pitting of prototypical sidewall coupons was observed in the CDIF workhorse testing. The most likely cause of the observed pitting, water leaks resulting from cooling water tube braze failures, has been remedied. New brazing procedures and isolation of the sidebar gas-side material from water contact will prevent sidebar pitting in the prototypical channel. Water-side corrosion tests reported in this quarterly report include the latest results of tungsten-copper elements at controlled pH, heat flux and voltage levels. In the combustion subsystem, efforts continued to focus on understanding and improving the current levels of slag recovery and seed utilization achieved by the combustor. Analytical support was also provided in the areas of slag rejection system operation, precombustor operation, and oil burner design modification. Channel data analysis activities continued in support of prototypical coupon testing at the CDIF. Analyses are presented on channel wall slagging behavior and sidewall voltage distributions.

  20. On the global solvability and the non-resistive limit of the one-dimensional compressible heat-conductive MHD equations

    NASA Astrophysics Data System (ADS)

    Zhang, Jianwen; Zhao, Xiaokui

    2017-03-01

    In general, the resistivity is inversely proportional to the electrical conductivity and is usually taken to be zero when the conducting fluid is of extremely high conductivity (e.g., ideal conductors). In this paper, the global well-posedness of strong solution to the one-dimensional compressible, viscous, heat-conductive, non-resistive magnetohydrodynamics equations with large data, and general heat-conductivity is proved. Moreover, the non-resistive limit is justified and the convergence rates in L2-norm are obtained, provided the heat-conductivity satisfies some growth condition.

  1. Laser-powered MHD generators for space application

    NASA Technical Reports Server (NTRS)

    Jalufka, N. W.

    1986-01-01

    Magnetohydrodynamic (MHD) energy conversion systems of the pulsed laser-supported detonation (LSD) wave, plasma MHD, and liquid-metal MHD (LMMHD) types are assessed for their potential as space-based laser-to-electrical power converters. These systems offer several advantages as energy converters relative to the present chemical, nuclear, and solar devices, including high conversion efficiency, simple design, high-temperature operation, high power density, and high reliability. Of these systems, the Brayton cycle liquid-metal MHD system appears to be the most attractive. The LMMHD technology base is well established for terrestrial applications, particularly with regard to the generator, mixer, and other system components. However, further research is required to extend this technology base to space applications and to establish the technology required to couple the laser energy into the system most efficiently. Continued research on each of the three system types is recommended.

  2. Including dietary fiber and resistant starch to increase satiety and reduce aggression in gestating sows.

    PubMed

    Sapkota, A; Marchant-Forde, J N; Richert, B T; Lay, D C

    2016-05-01

    Aggression during mixing of pregnant sows impacts sow welfare and productivity. The aim of this study was to increase satiety and reduce aggression by including dietary fiber and fermentable carbohydrates. Sows were housed in individual stalls 7 to 14 d after breeding (moving day was considered d 0 of treatment) and were fed (at 0700 h) with a CONTROL (corn-soybean meal based with no additional fiber sources), RSTARCH (10.8% resistant starch), BEETPULP (27.2% sugar beet pulp), SOYHULLS (19.1% soybean hulls), or INCSOY (14.05% soybean hulls) for 21 d (5 sows/diet × 5 diets × 8 replications = 200 sows). The CONTROL diet was targeted to contain 185 g(d∙sow) NDF and the other diets were targeted to contain 350 g(d∙sow) NDF. The INCSOY diet was fed at 2.2 kg/(d∙sow) and the other diets were fed at 2 kg(d∙sow). On d 22, sows were mixed in groups of 5 (at 1200 h). Behaviors in stalls (on d 1, 7, 14, and 21) and after mixing (d 22 and 23), heart rate (on d 1, 7, 14, and 21), blood metabolites (on d 2, 8, 15, 22, and 25), and the effects of diets on production were collected and analyzed. Sows stood more ( < 0.01) and rested less ( < 0.001) over time irrespective of the diet. Sows on BEETPULP stood more ( < 0.01) and sows on SOYHULLS rested more ( < 0.01). Sham chewing increased over days irrespective of the diet. Chewing behavior (bar and feeder) increased with days on diet ( < 0.001) and was lowest in sows on the SOYHULLS diet ( = 0.045). When mixed, biting frequency in the first hour was highest for sows on the CONTROL diet (236.5 ± 62.6) and lowest for sows on the RSTARCH diet (90.5 ± 30.5). Skin lesions increased ( < 0.001) 24 h after mixing sows irrespective of diet. Blood urea nitrogen (BUN) concentration was lowest in sows fed BEETPULP and SOYHULLS ( < 0.001). Serum glucose concentration was highest in sows fed RSTARCH and BEETPULP ( = 0.04), but there was no day effect ( = 0.62) or diet × day interaction ( = 0.60). The NEFA was greatest in sows fed

  3. Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats.

    PubMed

    Solberg Woods, Leah C; Holl, Katie L; Oreper, Daniel; Xie, Yuying; Tsaih, Shirng-Wern; Valdar, William

    2012-11-01

    Type 2 diabetes (T2D) is a disease of relative insulin deficiency resulting from both insulin resistance and beta cell failure. We have previously used heterogeneous stock (HS) rats to fine-map a locus for glucose tolerance. We show here that glucose intolerance in the founder strains of the HS colony is mediated by different mechanisms: insulin resistance in WKY and an insulin secretion defect in ACI, and we demonstrate a high degree of variability for measures of insulin resistance and insulin secretion in HS rats. As such, our goal was to use HS rats to fine-map several diabetes-related traits within a region on rat chromosome 1. We measured blood glucose and plasma insulin levels after a glucose tolerance test in 782 male HS rats. Using 97 SSLP markers, we genotyped a 68 Mb region on rat chromosome 1 previously implicated in glucose and insulin regulation. We used linkage disequilibrium mapping by mixed model regression with inferred descent to identify a region from 198.85 to 205.9 that contains one or more quantitative trait loci (QTL) for fasting insulin and a measure of insulin resistance, the quantitative insulin sensitivity check index. This region also encompasses loci identified for fasting glucose and Insulin_AUC (area under the curve). A separate <3 Mb QTL was identified for body weight. Using a novel penalized regression method we then estimated effects of alternative haplotype pairings under each locus. These studies highlight the utility of HS rats for fine-mapping genetic loci involved in the underlying causes of T2D.

  4. FUNDAMENTAL AREAS OF PHENOMENOLOGY (INCLUDING APPLICATIONS): A Particle Resistance Model for Flow through Porous Media

    NASA Astrophysics Data System (ADS)

    Wu, Jin-Sui; Yin, Shang-Xian; Zhao, Dong-Yu

    2009-06-01

    A particle model for resistance of flow in isotropic porous media is developed based on the fractal geometry theory and on the drag force flowing around sphere. The proposed model is expressed as a function of porosity, fluid property, particle size, fluid velocity (or Reynolds number) and fractal characters Df of particles in porous media. The model predictions are in good agreement with the experimental data. The validity of the proposed model is thus verified.

  5. Accurate expressions for solar cell fill factors including series and shunt resistances

    NASA Astrophysics Data System (ADS)

    Green, Martin A.

    2016-02-01

    Together with open-circuit voltage and short-circuit current, fill factor is a key solar cell parameter. In their classic paper on limiting efficiency, Shockley and Queisser first investigated this factor's analytical properties showing, for ideal cells, it could be expressed implicitly in terms of the maximum power point voltage. Subsequently, fill factors usually have been calculated iteratively from such implicit expressions or from analytical approximations. In the absence of detrimental series and shunt resistances, analytical fill factor expressions have recently been published in terms of the Lambert W function available in most mathematical computing software. Using a recently identified perturbative relationship, exact expressions in terms of this function are derived in technically interesting cases when both series and shunt resistances are present but have limited impact, allowing a better understanding of their effect individually and in combination. Approximate expressions for arbitrary shunt and series resistances are then deduced, which are significantly more accurate than any previously published. A method based on the insights developed is also reported for deducing one-diode fits to experimental data.

  6. Proteomic and metabolic analyses of early berry development in Vitis spp. including the period of ontogenic gain of resistance

    USDA-ARS?s Scientific Manuscript database

    Early development of grape berries is marked by several biological changes, including cell division and expansion, as berries initiate double sigmoid growth. In most genotypes, a significant gain of ontogenic resistance (OR) to some pathogens, including powdery mildew (PM) (Uncinula necator), also o...

  7. MHD Technology Transfer, Integration and Review Committee

    SciTech Connect

    Not Available

    1992-01-01

    This fifth semi-annual status report of the MHD Technology Transfer, Integration, and Review Committee (TTIRC) summarizes activities of the TTIRC during the period April 1990 through September 1990. It includes summaries and minutes of committee meetings, progress summaries of ongoing Proof-of-Concept (POC) contracts, discussions pertaining to technical integration issues in the POC program, and planned activities for the next six months.

  8. 3D MHD Simulations of Tokamak Disruptions

    NASA Astrophysics Data System (ADS)

    Woodruff, Simon; Stuber, James

    2014-10-01

    Two disruption scenarios are modeled numerically by use of the CORSICA 2D equilibrium and NIMROD 3D MHD codes. The work follows the simulations of pressure-driven modes in DIII-D and VDEs in ITER. The aim of the work is to provide starting points for simulation of tokamak disruption mitigation techniques currently in the CDR phase for ITER. Pressure-driven instability growth rates previously observed in simulations of DIIID are verified; Halo and Hiro currents produced during vertical displacements are observed in simulations of ITER with implementation of resistive walls in NIMROD. We discuss plans to exercise new code capabilities and validation.

  9. MHD channel development, part 3

    NASA Astrophysics Data System (ADS)

    1989-12-01

    This is the final report of work performed by Avco Research Laboratory, Inc. for the U.S. Department of Energy, Pittsburgh Energy Technology Center. The overall objectives of this program were: to contribute, by appropriate systematic experimental and analytical investigations, to the engineering data base necessary for the design and construction of MHD generators at the 50 MW(sub th) and ultimately at commercial sizes; and to design and fabricate specific hardware items to be tested at a site to be specified by DOE. Section 3.0, MHD Channel Design and Performance, reports experimental and analytical investigations related to MHD channel design and performance.

  10. MHD channel performance for potential early commercial MHD power plants

    NASA Technical Reports Server (NTRS)

    Swallom, D. W.

    1981-01-01

    The commercial viability of full and part load early commercial MHD power plants is examined. The load conditions comprise a mass flow of 472 kg/sec in the channel, Rosebud coal, 34% by volume oxygen in the oxidizer preheated to 922 K, and a one percent by mass seeding with K. The full load condition is discussed in terms of a combined cycle plant with optimized electrical output by the MHD channel. Various electrical load parameters, pressure ratios, and magnetic field profiles are considered for a baseload MHD generator, with a finding that a decelerating flow rate yields slightly higher electrical output than a constant flow rate. Nominal and part load conditions are explored, with a reduced gas mass flow rate and an enriched oxygen content. An enthalpy extraction of 24.6% and an isentropic efficiency of 74.2% is predicted for nominal operation of a 526 MWe MHD generator, with higher efficiencies for part load operation.

  11. MHD channel performance for potential early commercial MHD power plants

    NASA Technical Reports Server (NTRS)

    Swallom, D. W.

    1981-01-01

    The commercial viability of full and part load early commercial MHD power plants is examined. The load conditions comprise a mass flow of 472 kg/sec in the channel, Rosebud coal, 34% by volume oxygen in the oxidizer preheated to 922 K, and a one percent by mass seeding with K. The full load condition is discussed in terms of a combined cycle plant with optimized electrical output by the MHD channel. Various electrical load parameters, pressure ratios, and magnetic field profiles are considered for a baseload MHD generator, with a finding that a decelerating flow rate yields slightly higher electrical output than a constant flow rate. Nominal and part load conditions are explored, with a reduced gas mass flow rate and an enriched oxygen content. An enthalpy extraction of 24.6% and an isentropic efficiency of 74.2% is predicted for nominal operation of a 526 MWe MHD generator, with higher efficiencies for part load operation.

  12. Production of MHD fluid

    DOEpatents

    Lacey, James J.; Kurtzrock, Roy C.; Bienstock, Daniel

    1976-08-24

    A hot gaseous fluid of low ash content, suitable for use in open-cycle MHD (magnetohydrodynamic) power generation, is produced by means of a three-stage process comprising (1) partial combustion of a fossil fuel to produce a hot gaseous product comprising CO.sub.2 CO, and H.sub.2 O, (2) reformation of the gaseous product from stage (1) by means of a fluidized char bed, whereby CO.sub.2 and H.sub.2 O are converted to CO and H.sub.2, and (3) combustion of CO and H.sub.2 from stage (2) to produce a low ash-content fluid (flue gas) comprising CO.sub.2 and H.sub.2 O and having a temperature of about 4000.degree. to 5000.degree.F.

  13. MHD turbulent mixing layers

    SciTech Connect

    Esquivel, A.; Lazarian, A.; Benjamin, R.A.; Cho, J.; Leitner, S.N.

    2005-09-28

    Turbulent mixing layers have been proposed to explain observations of line ratios of highly ionized elements in the interstellar medium. We present preliminary results of numerical simulations of turbulent mixing layers in a magnetized medium. We developed a MHD code with radiative cooling. The magnetic field is expected to be a controlling factor by suppressing instabilities that lead to the turbulent mixing. Our results suggest that the difference in turbulent mixing in the unmagnetized case as compared to the case of a weak magnetic field, {beta} = Pgas/Pmag {approx} 10, is insignificant. With a more thorough exploration of parameter space, this work will provide more reliable diagnostics of turbulent mixing layers than those available today.

  14. A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.

    PubMed

    Zhong, Haihong; Davis, April; Ouzounova, Maria; Carrasco, Rosa A; Chen, Cui; Breen, Shannon; Chang, Yong S; Huang, Jiaqi; Liu, Zheng; Yao, Yihong; Hurt, Elaine; Moisan, Jacques; Fung, Michael; Tice, David A; Clouthier, Shawn G; Xiao, Zhan; Wicha, Max S; Korkaya, Hasan; Hollingsworth, Robert E

    2016-01-15

    Elevated levels of the proinflammatory cytokine IL6 are associated with poor survival outcomes in many cancers. Antibodies targeting IL6 and its receptor have been developed for chronic inflammatory disease, but they have not yet been shown to clearly benefit cancer patients, possibly due to antibody potency or the settings in which they have been tested. In this study, we describe the development of a novel high-affinity anti-IL6 antibody, MEDI5117, which features an extended half-life and potent inhibitory effects on IL6 biologic activity. MEDI5117 inhibited IL6-mediated activation of STAT3, suppressing the growth of several tumor types driven by IL6 autocrine signaling. In the same models, MEDI5117 displayed superior preclinical activity relative to a previously developed anti-IL6 antibody. Consistent with roles for IL6 in promoting tumor angiogenesis, we found that MEDI5117 inhibited the growth of endothelial cells, which can produce IL6 and support tumorigenesis. Notably, in tumor xenograft assays in mice, we documented the ability of MEDI5117 to enhance the antitumor activities of chemotherapy or gefitinib in combination treatment regimens. MEDI5117 also displayed robust activity on its own against trastuzumab-resistant HER2(+) tumor cells by targeting the CD44(+)CD24(-) cancer stem cell population. Collectively, our findings extend the evidence of important pleiotropic roles of IL6 in tumorigenesis and drug resistance, and offer a preclinical proof of concept for the use of IL6 antibodies in combination regimens to heighten therapeutic responses and overcome drug resistance.

  15. A Two-Dimensional Modeling Procedure to Estimate the Loss Equivalent Resistance Including the Saturation Effect.

    PubMed

    Salas, Rosa Ana

    2013-11-12

    We propose a modeling procedure specifically designed for a ferrite inductor excited by a waveform in time domain. We estimate the loss resistance in the core (parameter of the electrical model of the inductor) by means of a Finite Element Method in 2D which leads to significant computational advantages over the 3D model. The methodology is validated for an RM (rectangular modulus) ferrite core working in the linear and the saturation regions. Excellent agreement is found between the experimental data and the computational results.

  16. A Two-Dimensional Modeling Procedure to Estimate the Loss Equivalent Resistance Including the Saturation Effect

    PubMed Central

    Salas, Rosa Ana

    2013-01-01

    We propose a modeling procedure specifically designed for a ferrite inductor excited by a waveform in time domain. We estimate the loss resistance in the core (parameter of the electrical model of the inductor) by means of a Finite Element Method in 2D which leads to significant computational advantages over the 3D model. The methodology is validated for an RM (rectangular modulus) ferrite core working in the linear and the saturation regions. Excellent agreement is found between the experimental data and the computational results. PMID:28788382

  17. Antimicrobial Susceptibility Pattern of Methicillin-Resistance Staphylococcus aureus from Different Tertiary Care Hospitals Including Mymensingh Medical College Hospital.

    PubMed

    Roy, S; Hossain, M A; Paul, S K; Haque, N; Barman, T K; Ahmed, S; Nasreen, S A; Hossain, M S; Ahmed, F; Biswas, P; Nahar, F; Begum, H; Islam, M S

    2016-07-01

    The aim of this study was to detect antimicrobial susceptibilities and the presence of drug resistance genes of MRSA from tertiary care hospitals. This study was carried out in the Department of Microbiology, Mymensingh Medical College during the period from Jan, 2015 to Dec, 2015. Clinical samples, including wound swab, pus, exudates from diabetic ulcer and burn ulcer, aural swab, blood and urine were collected. Standard microbiological procedure & biochemical tests were carried out to detect S. aureus. Oxacillin disk diffusion test was done by Kirby-Bauer disk diffusion method. Total 69 isolates of S. aureus were selected for the study. The isolates were collected from three different tertiary care hospitals, of which 33, 27 and 9 were from Mymensingh Medical College Hospital (MMCH), BIRDEM hospital and Sir Salimullah Medical College Hospital (SSMCH) respectively. Among the 69 isolates, 17(24.6%) and 52(75.3%) were distinguished as MRSA and MSSA respectively by ODDM (Oxacillin disk diffusion method). In contrast, detection of presence and absence of mecA gene by PCR identified 20 (28.9%) and 49 (71.01%) isolates as MRSA and MSSA respectively. All of the S. aureus (MRSA and MSSA) isolates were sensitive to vancomycin and gentamicin. All MRSA isolates (100%) showed resistance to Penicillin and Oxacillin. Among the MRSA isolates about 88.2% were resistance to Ceftazidime, 64.7% were resistance to Erythromycin and Ciprofloxacin, 11.7% were resistance to Tetracycline. Among the MSSA isolates about 94.2% were resistance to Penicillin and 9.6% resistance to Ciprofloxacin. The MSSA were less resistance for non-beta lactam drugs than MRSA. Regarding drug resistance genes, the blaZ genes were present in 47 out of 49(95.8%) MSSA and in 18 out of 18 (100%) MRSA. The erythromycin resistance gene ermB was found in 8.69% isolates, of which highest 20% in MRSA and 4.08% in MSSA. The ermA was not found in any isolates. Among tetracycline resistance genes, tetK were detected in 10

  18. Neoclassical viscosity effects on resistive magnetohydrodynamic modes in toroidal geometry

    SciTech Connect

    Yang, J.G.; Oh, Y.H.; Choi, D.I. ); Kim, J.Y.; Horton, W. )

    1992-03-01

    The flux-surface-averaged linearized resistive magnetohydrodynamic (MHD) boundary-layer equations including the compressibility, diamagnetic drift, and neoclassical viscosity terms are derived in toroidal geometry. These equations describe the resistive layer dynamics of resistive MHD modes over the collisionality regime between the banana plateau and the Pfirsch--Schlueter. From the resulting equations, the effects of neoclassical viscosity on the stability of the tearing and resistive ballooning modes are investigated numerically. Also, a study is given for the problem of how the neoclassical resistive MHD mode is generated as the collisionality is reduced. It is shown that the neoclassical viscosity terms give a significant destabilizing effect for the tearing and resistive ballooning modes. This destabilization comes mainly from the reduction of the stabilizing effect of the parallel ion sound compression by the ion neoclassical viscosity. In the banana-plateau collisionality limit, where the compressibility is negligible, the dispersion relations of the tearing and resistive ballooning modes reduce to the same form, with the threshold value of the driving force given by {Delta}{sub {ital c}}=0. On the other hand, with the finite neoclassical effect it is found that the neoclassical resistive MHD instability is generated in agreement with previous results. Furthermore, it is shown that this later instability can be generated in a wide range of the collisionality including near the Pfirsch--Schlueter regime as well as the banana-plateau regime, suggesting that this mode is a probable cause of anomalous transport.

  19. The Termination Shock and Beyond: MHD Modeling

    SciTech Connect

    Ratkiewicz, Romana; Grygorczuk, Jolanta; Ben-Jaffel, Lotfi

    2005-08-01

    The 3D MHD models of the solar wind - interstellar plasma interaction including, in a self-consistent way, interactions of various populations of plasma and neutral particles should be ready to confront their results with the forthcoming data that will be obtained from space missions. In the near future, predictions made by sophisticated theoretical models should help refine the goals and optimize the capabilities of the instruments that will explore the far heliosphere and the LISM. In this paper we are giving a short survey of the MHD models and point out the problems, which need to be solved in the near future. As the example we show our recent numerical results with the simple model of the current sheet.

  20. Advances in Simulation of Wave Interaction with Extended MHD Phenomena

    SciTech Connect

    Batchelor, Donald B; Abla, Gheni; D'Azevedo, Ed F; Bateman, Glenn; Bernholdt, David E; Berry, Lee A; Bonoli, P.; Bramley, R; Breslau, Joshua; Chance, M.; Chen, J.; Choi, M.; Elwasif, Wael R; Foley, S.; Fu, GuoYong; Harvey, R. W.; Jaeger, Erwin Frederick; Jardin, S. C.; Jenkins, T; Keyes, David E; Klasky, Scott A; Kruger, Scott; Ku, Long-Poe; Lynch, Vickie E; McCune, Douglas; Ramos, J.; Schissel, D.; Schnack,; Wright, J.

    2009-01-01

    The Integrated Plasma Simulator (IPS) provides a framework within which some of the most advanced, massively-parallel fusion modeling codes can be interoperated to provide a detailed picture of the multi-physics processes involved in fusion experiments. The presentation will cover four topics: 1) recent improvements to the IPS, 2) application of the IPS for very high resolution simulations of ITER scenarios, 3) studies of resistive and ideal MHD stability in tokamk discharges using IPS facilities, and 4) the application of RF power in the electron cyclotron range of frequencies to control slowly growing MHD modes in tokamaks and initial evaluations of optimized location for RF power deposition.

  1. Advances in Simulation of Wave Interactions with Extended MHD Phenomena

    SciTech Connect

    Batchelor, Donald B; D'Azevedo, Eduardo; Bateman, Glenn; Bernholdt, David E; Bonoli, P.; Bramley, Randall B; Breslau, Joshua; Elwasif, Wael R; Foley, S.; Jaeger, Erwin Frederick; Jardin, S. C.; Klasky, Scott A; Kruger, Scott E; Ku, Long-Poe; McCune, Douglas; Ramos, J.; Schissel, David P; Schnack, Dalton D

    2009-01-01

    The Integrated Plasma Simulator (IPS) provides a framework within which some of the most advanced, massively-parallel fusion modeling codes can be interoperated to provide a detailed picture of the multi-physics processes involved in fusion experiments. The presentation will cover four topics: (1) recent improvements to the IPS, (2) application of the IPS for very high resolution simulations of ITER scenarios, (3) studies of resistive and ideal MHD stability in tokamak discharges using IPS facilities, and (4) the application of RF power in the electron cyclotron range of frequencies to control slowly growing MHD modes in tokamaks and initial evaluations of optimized location for RF power deposition.

  2. Conceptual design of a coal-fired MHD retrofit of the J. E. Corette Plant: Design definition

    SciTech Connect

    Not Available

    1988-02-01

    The design, construction, and operation of a fully integrated coal burning MHD/steam-power system has been identified as a necessary step for commercialization of MHD power gerneation. The addition of an MHD power system to an existing utility's conventional steam power plant is presently considered an efficient and attractive method for realization of this, and the conceptual design of a coal-fired MHD power plant has been initiated as an important item of the National MHD development program. Current activities of the MHD development program comprise proof-of-concepts testing of MHD topping cycle components and bottoming cycle components at the Components Development and Integration Facility (CDIF) and the Coal Fired Flow Facility (CFFF), respectively, at subscale levels. The MHD plant will provide for operation and testing of a fully integrated MHD/steam power system in a utility environment at a larger size consistent with its objectives. Its main objectives are to verify the technical and economic feasibility of commercial MHD power genration including environmental aspects and to provide electric utilities and equipment manufacturers with the necessary information and confidence to proceed with commercialization of MHD. The coal-fired J.E. Corette steam plant unit of the Montana Power Company at Billings, Montana has been selected for this MHD conceptual design activity.

  3. Adaptive Numerical Dissipation Control in High Order Schemes for Multi-D Non-Ideal MHD

    NASA Technical Reports Server (NTRS)

    Yee, H. C.; Sjoegreen, B.

    2005-01-01

    The required type and amount of numerical dissipation/filter to accurately resolve all relevant multiscales of complex MHD unsteady high-speed shock/shear/turbulence/combustion problems are not only physical problem dependent, but also vary from one flow region to another. In addition, proper and efficient control of the divergence of the magnetic field (Div(B)) numerical error for high order shock-capturing methods poses extra requirements for the considered type of CPU intensive computations. The goal is to extend our adaptive numerical dissipation control in high order filter schemes and our new divergence-free methods for ideal MHD to non-ideal MHD that include viscosity and resistivity. The key idea consists of automatic detection of different flow features as distinct sensors to signal the appropriate type and amount of numerical dissipation/filter where needed and leave the rest of the region free from numerical dissipation contamination. These scheme-independent detectors are capable of distinguishing shocks/shears, flame sheets, turbulent fluctuations and spurious high-frequency oscillations. The detection algorithm is based on an artificial compression method (ACM) (for shocks/shears), and redundant multiresolution wavelets (WAV) (for the above types of flow feature). These filters also provide a natural and efficient way for the minimization of Div(B) numerical error.

  4. A Mechanism for the Loading-Unloading Substorm Cycle Missing in MHD Global Magnetospheric Simulation Models

    NASA Technical Reports Server (NTRS)

    Klimas, A. J.; Uritsky, V.; Vassiliadis, D.; Baker, D. N.

    2005-01-01

    Loading and consequent unloading of magnetic flux is an essential element of the substorm cycle in Earth's magnetotail. We are unaware of an available global MHD magnetospheric simulation model that includes a loading- unloading cycle in its behavior. Given the central role that MHD models presently play in the development of our understanding of magnetospheric dynamics, and given the present plans for the central role that these models will play in ongoing space weather prediction programs, it is clear that this failure must be corrected. A 2-dimensional numerical driven current-sheet model has been developed that incorporates an idealized current- driven instability with a resistive MHD system. Under steady loading, the model exhibits a global loading- unloading cycle. The specific mechanism for producing the loading-unloading cycle will be discussed. It will be shown that scale-free avalanching of electromagnetic energy through the model, from loading to unloading, is carried by repetitive bursts of localized reconnection. Each burst leads, somewhat later, to a field configuration that is capable of exciting a reconnection burst again. This process repeats itself in an intermittent manner while the total field energy in the system falls. At the end of an unloading interval, the total field energy is reduced to well below that necessary to initiate the next unloading event and, thus, a loading-unloading cycle results. It will be shown that, in this model, it is the topology of bursty localized reconnection that is responsible for the appearance of the loading-unloading cycle.

  5. Design of closed-cycle MHD generator with nonequilibrium ionization and system

    NASA Technical Reports Server (NTRS)

    Voshall, R. E.; Wright, R. J.; Liebermann, R. W.

    1977-01-01

    A method is developed to include the nonequilibrium ionization process in the MHD generator duct design equations, and these equations are coupled to the thermodynamic conditions of the closed cycle system. This is used to relate MHD generator size, configuration and gas conditions to the overall thermodynamic efficiency of the system. The system studied consists of an MHD loop (Ar + Cs or He + Cs) topping a steam bottoming plant.

  6. Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant Conceptual Design Engineering Report (CDER)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The reference conceptual design of the magnetohydrodynamic (MHD) Engineering Test Facility (ETF), a prototype 200 MWe coal-fired electric generating plant designed to demonstrate the commercial feasibility of open cycle MHD, is summarized. Main elements of the design, systems, and plant facilities are illustrated. System design descriptions are included for closed cycle cooling water, industrial gas systems, fuel oil, boiler flue gas, coal management, seed management, slag management, plant industrial waste, fire service water, oxidant supply, MHD power ventilating

  7. MHD channel development, part 4

    NASA Astrophysics Data System (ADS)

    1989-12-01

    This is the final report of work performed by Avco Research Laboratory, Inc. for the U.S. Department of Energy, Pittsburgh Energy Technology Center. The overall objectives of this program were: to contribute, by appropriate systematic experimental and analytical investigations, to the engineering data base necessary for the design and construction of MHD generators at the 50 MW(sub th) and ultimately at commercial sizes; and to design and fabricate specific hardware items to be tested at a site to be specified by DOE. The program consisted of a series of related tasks, which are described in subsequent sections of this report. Section 4.0, MHD Channel Construction and Lifetime, reports experimental investigations related to MHD channel reliability and lifetime, where the principal aim is to improve the constructability, maintainability, and reliability of coal-fired, long-duration MHD channels.

  8. On two-dimensional magnetic reconnection with nonuniform resistivity

    NASA Astrophysics Data System (ADS)

    Malyshkin, Leonid M.; Kulsrud, Russell M.

    2010-12-01

    In this paper, two theoretical approaches for the calculation of the rate of quasi-stationary, two-dimensional magnetic reconnection with nonuniform anomalous resistivity are considered in the framework of incompressible magnetohydrodynamics (MHD). In the first, 'global' equations approach, the MHD equations are approximately solved for a whole reconnection layer, including the upstream and downstream regions and the layer center. In the second, 'local' equations approach, the equations are solved across the reconnection layer, including only the upstream region and the layer center. Both approaches give the same approximate answer for the reconnection rate. Our theoretical model is in agreement with the results of recent simulations of reconnection with spatially nonuniform resistivity.

  9. Eighth international conference on MHD electrical power generation. Volume 4

    SciTech Connect

    Not Available

    1983-01-01

    The VIIIth International Conference on MHD Electrical Power Generation was convened at the initiative of the International Liaison Group on MHD Electrical Power Generation by the USSR Academy of Sciences (Institute of High Temperature) and under the sponsorship of: UNESCO; Council for Mutual Economic Assistance (COMECON); Energoinvest (Yugoslavia), Control Data Corporation (USA); and Bhabha Atomic Research Centre (India). The proceedings of the VIIIth International Conference on MHD Electrical Power Generation contain the results of most recent R and D work aimed at practical realization of this advanced method of electrical power generation. The papers presented to the Conference deal with heat-generating schemes and cycles, conceptual and detail designs of MHD power plants, including that of the first commercial 500-MW power generating unit presently under construction in the USSR. Research results obtained in pilot and experimental facilities in the USSR, USA, Poland, Japan, Netherlands and other countries are described. Volume 4 was concerned with Materials, Combined-Cycle, Liquid-Metal MHD, and Closed-Cycle Disk-Type MHD Generator. This DOE report contains full translations in English of all the papers in Volume 4. These have been entered individually into EDB and ERA. (LTN)

  10. The role of the electron convection term for the parallel electric field and electron acceleration in MHD simulations

    SciTech Connect

    Matsuda, K.; Terada, N.; Katoh, Y.; Misawa, H.

    2011-08-15

    There has been a great concern about the origin of the parallel electric field in the frame of fluid equations in the auroral acceleration region. This paper proposes a new method to simulate magnetohydrodynamic (MHD) equations that include the electron convection term and shows its efficiency with simulation results in one dimension. We apply a third-order semi-discrete central scheme to investigate the characteristics of the electron convection term including its nonlinearity. At a steady state discontinuity, the sum of the ion and electron convection terms balances with the ion pressure gradient. We find that the electron convection term works like the gradient of the negative pressure and reduces the ion sound speed or amplifies the sound mode when parallel current flows. The electron convection term enables us to describe a situation in which a parallel electric field and parallel electron acceleration coexist, which is impossible for ideal or resistive MHD.

  11. Perturbed Stability Analysis of External Ideal MHD Modes

    NASA Astrophysics Data System (ADS)

    Comer, K. J.; Callen, J. D.; Hegna, C. C.; Garstka, G. D.; Turnbull, A. D.; Garofalo, A. M.; Cowley, S. C.

    2002-11-01

    Traditionally, numerical parameter scans are performed to study the effects of equilibrium shaping and profiles on long wavelength ideal MHD instabilities. Previously, we introduced a new perturbative technique to more efficiently explore these dependencies: changes in delta-W due to small equilibrium variations are found using a perturbation of the energy principle rather than with an eigenvalue-solver instability code. With this approach, the stability properties of similar equilibria can be efficiently explored without generating complete numerical results for every set of parameters (which is time-intensive for accurate representations of several configurations). Here, we apply this approach to toroidal geometry using GATO (an ideal MHD stability code) and experimental equilibria. In particular, we explore ideal MHD stability of external kink modes in the spherical tokamak Pegasus and resistive wall modes in DIII-D.

  12. Propagation and Dissipation of MHD Waves in Coronal Holes

    NASA Astrophysics Data System (ADS)

    Dwivedi, B. N.

    2006-11-01

    bholadwivedi@gmail.com In view of the landmark result on the solar wind outflow, starting between 5 Mm and 20 Mm above the photosphere in magnetic funnels, we investigate the propagation and dissipation of MHD waves in coronal holes. We underline the importance of Alfvén wave dissipation in the magnetic funnels through the viscous and resistive plasma. Our results show that Alfvén waves are one of the primary energy sources in the innermost part of coronal holes where the solar wind outflow starts. We also consider compressive viscosity and thermal conductivity to study the propagation and dissipation of long period slow longitudinal MHD waves in polar coronal holes. We discuss their likely role in the line profile narrowing, and in the energy budget for coronal holes and the solar wind. We compare the contribution of longitudinal MHD waves with high frequency Alfvén waves.

  13. Culture methods impact recovery of antibiotic-resistant Enterococci including Enterococcus cecorum from pre- and postharvest chicken.

    PubMed

    Suyemoto, M M; Barnes, H J; Borst, L B

    2017-03-01

    Pathogenic strains of Enterococcus cecorum (EC) expressing multidrug resistance have emerged. In National Antimicrobial Resistance Monitoring System (NARMS) data, EC is rarely recovered from chickens. Two NARMS methodologies (FDA and USDA) were compared with standard culture (SC) techniques for recovery of EC. NARMS methods failed to detect EC in 58 caecal samples, 20 chicken breast or six whole broiler samples. EC was recovered from 1 of 38 (2·6%) and 2 of 38 (5·2%) preharvest spinal lesions (USDA and FDA method, respectively). In contrast, using the SC method, EC was recovered from 44 of 53 (83%) caecal samples, all 38 (100%) spinal lesions, 14 of 20 (70%) chicken breast samples, and all three spinal lesions identified in whole carcasses. Compared with other Enterococcus spp., EC isolates had a higher prevalence of resistance to macrolides. The NARMS methods significantly affected recovery of enterococcal species other than EC. When the postharvest FDA method was applied to preharvest caecal samples, isolates of Enterococcus faecium were preferentially recovered. All 11 E. faecium isolates were multidrug resistant, including resistance to penicillin, daptomycin and linezolid. These findings confirm that current methodologies may not accurately identify the amount and range of antimicrobial resistance of enterococci from chicken sources.

  14. C-Mod MHD stability analysis with LHCD

    NASA Astrophysics Data System (ADS)

    Ebrahimi, Fatima; Bhattacharjee, A.; Delgado, L.; Scott, S.; Wilson, J. R.; Wallace, G. M.; Shiraiwa, S.; Mumgaard, R. T.

    2016-10-01

    In lower hybrid current drive (LHCD) experiments on the Alcator C-Mod, sawtooth activity could be suppressed as the safety factor q on axis is raised above unity. However, in some of these experiments, after applying LHCD, the onset of MHD mode activity caused the current drive efficiency to significantly drop. Here, we study the stability of these experiments by performing MHD simulations using the NIMROD code starting with experimental EFIT equilibria. First, consistent with the LHCD experiment with no signature of MHD activity, MHD mode activity was also absent in the simulations. Second, for experiments with MHD mode activity, we find that a core n=1 reconnecting mode with dominate poloidal modes of m=2,3 is unstable. This mode is a resistive current-driven mode as its growth rate scales with a negative power of the Lundquist number in the simulations. In addition, with further enhanced reversed-shear q profile in the simulations, a core double tearing mode is found to be unstable. This work is supported by U.S. DOE cooperative agreement DE-FC02-99ER54512 using the Alcator C-Mod tokamak, a DOE Office of Science user facility.

  15. Dynamo action in dissipative, forced, rotating MHD turbulence

    NASA Astrophysics Data System (ADS)

    Shebalin, John V.

    2016-06-01

    Magnetohydrodynamic (MHD) turbulence is an inherent feature of large-scale, energetic astrophysical and geophysical magnetofluids. In general, these are rotating and are energized through buoyancy and shear, while viscosity and resistivity provide a means of dissipation of kinetic and magnetic energy. Studies of unforced, rotating, ideal (i.e., non-dissipative) MHD turbulence have produced interesting results, but it is important to determine how these results are affected by dissipation and forcing. Here, we extend our previous work and examine dissipative, forced, and rotating MHD turbulence. Incompressibility is assumed, and finite Fourier series represent turbulent velocity and magnetic field on a 643 grid. Forcing occurs at an intermediate wave number by a method that keeps total energy relatively constant and allows for injection of kinetic and magnetic helicity. We find that 3-D energy spectra are asymmetric when forcing is present. We also find that dynamo action occurs when forcing has either kinetic or magnetic helicity, with magnetic helicity injection being more important. In forced, dissipative MHD turbulence, the dynamo manifests itself as a large-scale coherent structure that is similar to that seen in the ideal case. These results imply that MHD turbulence, per se, may play a fundamental role in the creation and maintenance of large-scale (i.e., dipolar) stellar and planetary magnetic fields.

  16. Dynamo action in dissipative, forced, rotating MHD turbulence

    SciTech Connect

    Shebalin, John V.

    2016-06-15

    Magnetohydrodynamic (MHD) turbulence is an inherent feature of large-scale, energetic astrophysical and geophysical magnetofluids. In general, these are rotating and are energized through buoyancy and shear, while viscosity and resistivity provide a means of dissipation of kinetic and magnetic energy. Studies of unforced, rotating, ideal (i.e., non-dissipative) MHD turbulence have produced interesting results, but it is important to determine how these results are affected by dissipation and forcing. Here, we extend our previous work and examine dissipative, forced, and rotating MHD turbulence. Incompressibility is assumed, and finite Fourier series represent turbulent velocity and magnetic field on a 64{sup 3} grid. Forcing occurs at an intermediate wave number by a method that keeps total energy relatively constant and allows for injection of kinetic and magnetic helicity. We find that 3-D energy spectra are asymmetric when forcing is present. We also find that dynamo action occurs when forcing has either kinetic or magnetic helicity, with magnetic helicity injection being more important. In forced, dissipative MHD turbulence, the dynamo manifests itself as a large-scale coherent structure that is similar to that seen in the ideal case. These results imply that MHD turbulence, per se, may play a fundamental role in the creation and maintenance of large-scale (i.e., dipolar) stellar and planetary magnetic fields.

  17. Performance evaluations of MHD generator tests at CDIF

    NASA Astrophysics Data System (ADS)

    Daniel, V. W.; Lineberry, J. T.; Wu, Y. C. L.

    1992-01-01

    Experimental data from CDIF coal-fired MHD generator test 90-DIAG-3 are analyzed. The results of two independent studies are presented and compared. Both studies impose experimental data upon modeling to derive information on plasma properties and electrical loss mechanisms. The first technique applies routine electrical data to special solutions of the MHD electrical equations to determine gross electrophysical properties and nonuniformity parameters of the generator medium (plasma plus slag) over one pitch control volumes along the length of the MHD channel. The second technique pits a predictive 1D MHD generator model against input experimental Hall voltage data. The generator model solves for the MHD plasmadynamic and electrical processes required to fit the experimental voltage distribution to determine plasma properties with wall and electrical losses. Among the parameters that are estimated by these methods are conductivity, Hall parameter, interelectrode resistances, and the plasma nonuniformity factors (e.g., G). The magnitude of leakage current (slag or otherwise) can also inferred from these analyses.

  18. Susceptibility trends including emergence of linezolid resistance among coagulase-negative staphylococci and meticillin-resistant Staphylococcus aureus from invasive infections.

    PubMed

    Decousser, Jean-Winoc; Desroches, Marine; Bourgeois-Nicolaos, Nadège; Potier, Julien; Jehl, François; Lina, Gérard; Cattoir, Vincent; Vandenesh, François; Doucet-Populaire, Florence

    2015-12-01

    Multiresistance in staphylococci constitutes a major challenge for the antimicrobial chemotherapy of invasive infections such as bacteraemia or bone and joint infections (BJIs). A nationwide prospective study was performed to detect antimicrobial resistance trends among staphylococci causing invasive infections. Between October 2011 and February 2012, 367 meticillin-resistant Staphylococcus aureus (MRSA) and 695 coagulase-negative staphylococci (CoNS) were collected from 37 French hospitals, mainly from bacteraemia (59.9%) and osteoarticular infections (29.0%). Minimum inhibitory concentrations (MICs) were determined by broth microdilution, and specific screening and confirmation tests were performed to detect heterogeneous vancomycin-intermediate S. aureus (hVISA). Staphylococcal isolates exhibiting a linezolid MIC>4 mg/L were further characterised to determinate their clonal relationships and the mechanism of resistance. MRSA exhibited additional resistances, including levofloxacin (82% associated resistance), gentamicin (13.6%), fusidic acid (13.6%) and rifampicin (6.5%), compromising oral step-down therapy in BJIs. Only two hVISA strains (0.5%) were identified. Among the CoNS, mainly Staphylococcus epidermidis (506/695; 72.8%), resistance to first- and second-line agents was more common. Linezolid resistance was identified in 10 CoNS (1.4%). The most frequent linezolid resistance mechanism was the G2576T mutation in 23S rDNA (9/10). For the first time in France, the cfr gene was found in five related sequence type 2 (ST2) S. epidermidis from two different hospitals, in association with ribosomal RNA and L3 ribosomal protein mutations. These national data must be considered when selecting empirical treatment for invasive staphylococcal infections. Moreover, the emergence and spread of linezolid-resistant CoNS carrying the cfr gene is of concern.

  19. Thermodynamic MHD Modeling of Coronal Mass Ejections

    NASA Astrophysics Data System (ADS)

    Linker, Jon A.; Lionello, R.; Mikic, Z.; Riley, P.; Titov, V.

    2007-05-01

    Coronal mass ejections (CMEs) disrupt the large-scale coronal magnetic field and propel plasma and magnetic flux outward into interplanetary space. The most energetic CMEs typically originate from active regions on the Sun. Accurately modeling active regions while also capturing the entire corona requires MHD models that include energy transport (radiative losses,anisotropic thermal conduction, and coronal heating) in the transition region and solar corona. We refer to this as the thermodynamic MHD model. The more accurate representation of energy flow in the thermodynamic MHD model allows us to to compute simulated EUV and X-ray emission as would be observed from spacecraft such as SOHO, STEREO, and Hinode. With this approach, theorists no longer get to argue what emission they think their favorite model's magnetic field evolution implies; we can actually go compute the emission and compare with observations. As an example, we show a simulation of the May 12, 1997 CME, and compare the simulated emission with observations from the actual event of dimming regions, postflare loops, and reformation of loops near the northern polar coronal hole. Work supported by NASA, NSF and the Center for Integrated Space Weather Modeling (an NSF Science and Technology Center).

  20. The Role of Kinetic Effects, Including Plasma Rotation and Energetic Particles, in Resistive Wall Mode Stability

    NASA Astrophysics Data System (ADS)

    Berkery, John W.

    2009-11-01

    Continuous, disruption-free operation of tokamaks requires stabilization of the resistive wall mode (RWM). Theoretically, the RWM is thought to be stabilized by energy dissipation mechanisms that depend on plasma rotation and other parameters, with kinetic effects being emphasized.footnotetextB. Hu et al., Phys. Plasmas 12 (2005) 057301. Experiments in NSTX show that the RWM can be destabilized in high rotation plasmas while low rotation plasmas can be stable, which calls into question the concept of a simple critical plasma rotation threshold for stability. The present work tests theoretical stabilization mechanisms against experimental discharges with various plasma rotation profiles created by applying non-resonant n=3 braking, and with various fast particle fractions. Kinetic modification of ideal stability is calculated with the MISK code, using experimental equilibrium reconstructions. Analysis of NSTX discharges with unstable RWMs predicts near-marginal mode growth rates. Trapped ions provide the dominant kinetic resonances, while fast particles contribute an important stabilizing effect. Increasing or decreasing rotation in the calculation drives the prediction farther from the marginal point, showing that unlike simpler critical rotation theories, kinetic theory allows a more complex relationship between plasma rotation and RWM stability. Results from JT-60U show that energetic particle modes can trigger RWMsfootnotetextG. Matsunaga et al., IAEA FEC 2008 Paper EX/5-2.. Kinetic theory may explain how fast particle loss can trigger RWMs through the loss of an important stabilization mechanism. These results are applied to ITER advanced scenario equilibria to determine the impact on RWM stability.

  1. Including dietary fiber and resistant starch to increase satiety and reduce aggression in gestating sows

    USDA-ARS?s Scientific Manuscript database

    The swine industry is under a great deal of pressure to return sows to group housing. However, aggression during mixing of pregnant sows impacts sow welfare and productivity. The aim of this study was to increase satiety and reduce aggression by including dietary fiber and fermentable carbohydrate. ...

  2. Antibacterial and antibiotic resistance modifying activity of the extracts from Allanblackia gabonensis, Combretum molle and Gladiolus quartinianus against Gram-negative bacteria including multi-drug resistant phenotypes.

    PubMed

    Fankam, Aimé G; Kuiate, Jules R; Kuete, Victor

    2015-06-30

    Bacterial resistance to antibiotics is becoming a serious problem worldwide. The discovery of new and effective antimicrobials and/or resistance modulators is necessary to tackle the spread of resistance or to reverse the multi-drug resistance. We investigated the antibacterial and antibiotic-resistance modifying activities of the methanol extracts from Allanblackia gabonensis, Gladiolus quartinianus and Combretum molle against 29 Gram-negative bacteria including multi-drug resistant (MDR) phenotypes. The broth microdilution method was used to determine the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of the samples meanwhile the standard phytochemical methods were used for the preliminary phytochemical screening of the plant extracts. Phytochemical analysis showed the presence of alkaloids, flavonoids, phenols and tannins in all studied extracts. Other chemical classes of secondary metabolites were selectively presents. Extracts from A. gabonensis and C. molle displayed a broad spectrum of activity with MICs varying from 16 to 1024 μg/mL against about 72.41% of the tested bacteria. The extract from the fruits of A. gabonensis had the best activity, with MIC values below 100 μg/mL on 37.9% of tested bacteria. Percentages of antibiotic-modulating effects ranging from 67 to 100% were observed against tested MDR bacteria when combining the leaves extract from C. molle (at MIC/2 and MIC/4) with chloramphenicol, kanamycin, streptomycin and tetracycline. The overall results of the present study provide information for the possible use of the studied plant, especially Allanblackia gabonensis and Combretum molle in the control of Gram-negative bacterial infections including MDR species as antibacterials as well as resistance modulators.

  3. MHD-EMP protection guidelines

    NASA Astrophysics Data System (ADS)

    Barnes, P. R.; Vance, E. F.

    A nuclear detonation at altitudes several hundred kilometers above the earth will severely distort the earth's magnetic field and result in a strong magnetohydrodynamic electromagnetic pulse (MHD-EMP). The geomagnetic disturbance interacts with the soil to induce current and horizontal electric gradients. MHD-EMP, also called E3 since it is the third component of the high-altitude EMP (HEMP), lasts over 100 s after an exoatmospheric burst. MHD-EMP is similar to solar geomagnetic storms in it's global and low frequency (less than 1 Hz) nature except that E3 can be much more intense with a far shorter duration. When the MHD-EMP gradients are integrated over great distances by power lines, communication cables, or other long conductors, the induced voltages are significant. (The horizontal gradients in the soil are too small to induce major responses by local interactions with facilities.) The long pulse waveform for MHD-EMP-induced currents on long lines has a peak current of 200 A and a time-to-half-peak of 100 s. If this current flows through transformer windings, it can saturate the magnetic circuit and cause 60 Hz harmonic production. To mitigate the effects of MHD-EMP on a facility, long conductors must be isolated from the building and the commercial power harmonics and voltage swings must be addressed. The transfer switch would be expected to respond to the voltage fluctuations as long as the harmonics have not interfered with the switch control circuitry. The major sources of MHD-EMP induced currents are the commercial power lines and neutral; neutral current indirect coupling to the facility power or ground system via the metal fence, powered gate, parking lights, etc; metal water pipes; phone lines; and other long conductors that enter or come near the facility. The major source of harmonics is the commercial power system.

  4. MHD-EMP protection guidelines

    SciTech Connect

    Barnes, P.R.; Vance, E.F.

    1992-01-01

    A nuclear detonation at altitudes several hundred kilometers above the earth will severely distort the earth's magnetic field and result in a strong magnetohyrodynamic electromagnetic pulse (MHD-EMP). The geomagnetic disturbance interacts with the soil to induce current and horizontal electric gradients. The geomagnetic disturbance interacts with the soil to induced current and horizontal electric gradients in the earth. MHD-EMP, also called E3 since it is the third component of the high-altitude EMP (HEMP), lasts over 100 s after the exoatmospheric burst. MHD-EMP is similar to solar geomagnetic storms in it's global and low frequency (less than 1 Hz) nature except that E3 can be much more intense with a far shorter duration. When the MHD-EMP gradients are integrated over great distances by power lines, communication cables, or other long conductors, the induced voltages are significant. (The horizontal gradients in the soil are too small to induce major responses by local interactions with facilities.) The long pulse waveform for MHD-EMP-induced currents on long lines has a peak current of 200 A and a time-to-half-peak of 100 s. If this current flows through transformer windings, it can saturate the magnetic circuit and cause 60 Hz harmonic production. To mitigate the effects of MHD-EMP on a facility, long conductors must be isolated from the building and the commercial power harmonics and voltage swings must be addressed. The transfer switch would be expected to respond to the voltage fluctuations as long as the harmonics have not interfered with the switch control circuitry. The major sources of MHD-EMP induced currents are the commercial power lines and neutral; neutral current indirect coupling to the facility power or ground system via the metal fence, powered gate, parking lights, etc; metal water pipes; phone lines; and other long conductors that enter or come near the facility. The major source of harmonics is the commercial power system.

  5. The Biermann catastrophe of numerical MHD

    NASA Astrophysics Data System (ADS)

    Graziani, C.; Tzeferacos, P.; Lee, D.; Lamb, D. Q.; Weide, K.; Fatenejad, M.; Miller, J.

    2016-05-01

    The Biermann Battery effect is frequently invoked in cosmic magnetogenesis and studied in High-Energy Density laboratory physics experiments. Unfortunately, direct implementation of the Biermann effect in MHD codes is known to produce unphysical magnetic fields at shocks whose value does not converge with resolution. We show that this convergence breakdown is due to naive discretization, which fails to account for the fact that discretized irrotational vector fields have spurious solenoidal components that grow without bound near a discontinuity. We show that careful consideration of the kinetics of ion viscous shocks leads to a formulation of the Biermann effect that gives rise to a convergent algorithm. We note a novel physical effect a resistive magnetic precursor in which Biermann-generated field in the shock “leaks” resistively upstream. The effect appears to be potentially observable in experiments at laser facilities.

  6. The underappreciated in vitro activity of tedizolid against Bacteroides fragilis species, including strains resistant to metronidazole and carbapenems.

    PubMed

    Goldstein, Ellie J C; Citron, Diane M; Tyrrell, Kerin L; Leoncio, Elisa S; Merriam, C Vreni

    2017-02-01

    Because Bacteroides fragilis has the ability to develop mechanisms of resistance to almost all antibiotics, we studied the comparative in vitro activity of tedizolid against 124 Bacteroides group species clinical isolates, including carbapenem, metronidazole and piperacillin-tazobactam resistant strains. Tedizolid had an MIC90 of 2 μg/ml (range, 0.5-4 μg/ml) and was 1-4 times more active than linezolid that had an MIC90 of 8 μg/ml (range, 2-16 μg/ml). It was also active (MICs 0.5-2 μg/ml) against the 27 ertapenem, 2 metronidazole and 12 piperacillin-tazobactam resistant strains tested. This suggests that tedizolid may be useful treating infections, including bacteremias, due to resistant B. fragilis group species, as well as, mixed skin and soft tissue infections such as diabetic foot infections caused by Gram-positive aerobes and B. fragilis group species. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. An advanced implicit solver for MHD

    NASA Astrophysics Data System (ADS)

    Udrea, Bogdan

    A new implicit algorithm has been developed for the solution of the time-dependent, viscous and resistive single fluid magnetohydrodynamic (MHD) equations. The algorithm is based on an approximate Riemann solver for the hyperbolic fluxes and central differencing applied on a staggered grid for the parabolic fluxes. The algorithm employs a locally aligned coordinate system that allows the solution to the Riemann problems to be solved in a natural direction, normal to cell interfaces. The result is an original scheme that is robust and reduces the complexity of the flux formulas. The evaluation of the parabolic fluxes is also implemented using a locally aligned coordinate system, this time on the staggered grid. The implicit formulation employed by WARP3 is a two level scheme that was applied for the first time to the single fluid MHD model. The flux Jacobians that appear in the implicit scheme are evaluated numerically. The linear system that results from the implicit discretization is solved using a robust symmetric Gauss-Seidel method. The code has an explicit mode capability so that implementation and test of new algorithms or new physics can be performed in this simpler mode. Last but not least the code was designed and written to run on parallel computers so that complex, high resolution runs can be per formed in hours rather than days. The code has been benchmarked against analytical and experimental gas dynamics and MHD results. The benchmarks consisted of one-dimensional Riemann problems and diffusion dominated problems, two-dimensional supersonic flow over a wedge, axisymmetric magnetoplasmadynamic (MPD) thruster simulation and three-dimensional supersonic flow over intersecting wedges and spheromak stability simulation. The code has been proven to be robust and the results of the simulations showed excellent agreement with analytical and experimental results. Parallel performance studies showed that the code performs as expected when run on parallel

  8. Brownian dynamics simulations of a flexible polymer chain which includes continuous resistance and multibody hydrodynamic interactions.

    PubMed

    Butler, Jason E; Shaqfeh, Eric S G

    2005-01-01

    Using methods adapted from the simulation of suspension dynamics, we have developed a Brownian dynamics algorithm with multibody hydrodynamic interactions for simulating the dynamics of polymer molecules. The polymer molecule is modeled as a chain composed of a series of inextensible, rigid rods with constraints at each joint to ensure continuity of the chain. The linear and rotational velocities of each segment of the polymer chain are described by the slender-body theory of Batchelor [J. Fluid Mech. 44, 419 (1970)]. To include hydrodynamic interactions between the segments of the chain, the line distribution of forces on each segment is approximated by making a Legendre polynomial expansion of the disturbance velocity on the segment, where the first two terms of the expansion are retained in the calculation. Thus, the resulting linear force distribution is specified by a center of mass force, couple, and stresslet on each segment. This method for calculating the hydrodynamic interactions has been successfully used to simulate the dynamics of noncolloidal suspensions of rigid fibers [O. G. Harlen, R. R. Sundararajakumar, and D. L. Koch, J. Fluid Mech. 388, 355 (1999); J. E. Butler and E. S. G. Shaqfeh, J. Fluid Mech. 468, 204 (2002)]. The longest relaxation time and center of mass diffusivity are among the quantities calculated with the simulation technique. Comparisons are made for different levels of approximation of the hydrodynamic interactions, including multibody interactions, two-body interactions, and the "freely draining" case with no interactions. For the short polymer chains studied in this paper, the results indicate a difference in the apparent scaling of diffusivity with polymer length for the multibody versus two-body level of approximation for the hydrodynamic interactions.

  9. Brownian dynamics simulations of a flexible polymer chain which includes continuous resistance and multibody hydrodynamic interactions

    NASA Astrophysics Data System (ADS)

    Butler, Jason E.; Shaqfeh, Eric S. G.

    2005-01-01

    Using methods adapted from the simulation of suspension dynamics, we have developed a Brownian dynamics algorithm with multibody hydrodynamic interactions for simulating the dynamics of polymer molecules. The polymer molecule is modeled as a chain composed of a series of inextensible, rigid rods with constraints at each joint to ensure continuity of the chain. The linear and rotational velocities of each segment of the polymer chain are described by the slender-body theory of Batchelor [J. Fluid Mech. 44, 419 (1970)]. To include hydrodynamic interactions between the segments of the chain, the line distribution of forces on each segment is approximated by making a Legendre polynomial expansion of the disturbance velocity on the segment, where the first two terms of the expansion are retained in the calculation. Thus, the resulting linear force distribution is specified by a center of mass force, couple, and stresslet on each segment. This method for calculating the hydrodynamic interactions has been successfully used to simulate the dynamics of noncolloidal suspensions of rigid fibers [O. G. Harlen, R. R. Sundararajakumar, and D. L. Koch, J. Fluid Mech. 388, 355 (1999); J. E. Butler and E. S. G. Shaqfeh, J. Fluid Mech. 468, 204 (2002)]. The longest relaxation time and center of mass diffusivity are among the quantities calculated with the simulation technique. Comparisons are made for different levels of approximation of the hydrodynamic interactions, including multibody interactions, two-body interactions, and the "freely draining" case with no interactions. For the short polymer chains studied in this paper, the results indicate a difference in the apparent scaling of diffusivity with polymer length for the multibody versus two-body level of approximation for the hydrodynamic interactions.

  10. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-03-01

    The Magnetohydrodynamics (MHD) Integrated Topping Cycle (ITC) Project represents the culmination of the proof-of-concept (POC) development stage in the US Department of Energy (DOE) program to advance MHD technology to early commercial development stage utility power applications. The project is a joint effort, combining the skills of three topping cycle component developers: TRW, Avco/TDS, and Westinghouse. TRW, the prime contractor and system integrator, is responsible for the 50 thermal megawatt (50 MW{sub t}) slagging coal combustion subsystem. Avco/TDS is responsible for the MHD channel subsystem (nozzle, channel, diffuser, and power conditioning circuits), and Westinghouse is responsible for the current consolidation subsystem. The ITC Project will advance the state-of-the-art in MHD power systems with the design, construction, and integrated testing of 50 MW{sub t} power train components which are prototypical of the equipment that will be used in an early commercial scale MHD utility retrofit. Long duration testing of the integrated power train at the Component Development and Integration Facility (CDIF) in Butte, Montana will be performed, so that by the early 1990's, an engineering data base on the reliability, availability, maintainability and performance of the system will be available to allow scaleup of the prototypical designs to the next development level. This Sixteenth Quarterly Technical Progress Report covers the period May 1, 1991 to July 31, 1991.

  11. Latent introduction to the Netherlands of multiple antibiotic resistance including NDM-1 after hospitalisation in Egypt, August 2013.

    PubMed

    Bathoorn, E; Friedrich, A W; Zhou, K; Arends, J P; Borst, D M; Grundmann, H; Rossen, J W

    2013-10-17

    We describe the introduction of various multi-drug resistant bacterial strains, including an NDM-1-producing Klebsiella pneumoniae, through a traveller returning from Egypt, where they had been admitted to a private hospital. All family members of the patient were colonised with one or more extended-spectrum beta-lactamase producing strains. These findings emphasise the importance of adherence to isolation precautions for returning patients and suggest the need for inclusion of Enterobacteriaceae in admission screening.

  12. Coronal extension of the MURaM radiative MHD code: From quiet sun to flare simulations

    NASA Astrophysics Data System (ADS)

    Rempel, Matthias D.; Cheung, Mark

    2016-05-01

    We present a new version of the MURaM radiative MHD code, which includes a treatment of the solar corona in terms of MHD, optically thin radiative loss and field-aligned heat conduction. In order to relax the severe time-step constraints imposed by large Alfven velocities and heat conduction we use a combination of semi-relativistic MHD with reduced speed of light ("Boris correction") and a hyperbolic formulation of heat conduction. We apply the numerical setup to 4 different setups including a mixed polarity quiet sun, an open flux region, an arcade solution and an active region setup and find all cases an amount of coronal heating sufficient to maintain a corona with temperatures from 1 MK (quiet sun) to 2 MK (active region, arcade). In all our setups the Poynting flux is self-consistently created by photospheric and sub-photospheric magneto-convection in the lower part of our simulation domain. Varying the maximum allowed Alfven velocity ("reduced speed of light") leads to only minor changes in the coronal structure as long as the limited Alfven velocity remains larger than the speed of sound and about 1.5-3 times larger than the peak advection velocity. We also found that varying details of the numerical diffusivities that govern the resistive and viscous energy dissipation do not strongly affect the overall coronal heating, but the ratio of resistive and viscous energy dependence is strongly dependent on the effective numerical magnetic Prandtl number. We use our active region setup in order to simulate a flare triggered by the emergence of a twisted flux rope into a pre-existing bipolar active region. Our simulation yields a series of flares, with the strongest one reaching GOES M1 class. The simulation reproduces many observed properties of eruptions such as flare ribbons, post flare loops and a sunquake.

  13. An Antimicrobial Metabolite from Bacillus sp.: Significant Activity Against Pathogenic Bacteria Including Multidrug-Resistant Clinical Strains

    PubMed Central

    Chalasani, Ajay G.; Dhanarajan, Gunaseelan; Nema, Sushma; Sen, Ramkrishna; Roy, Utpal

    2015-01-01

    In this study, the cell free modified tryptone soya broth (pH 7.4 ± 0.2) of Bacillus subtilis URID 12.1 showed significant antimicrobial activity against multidrug-resistant strains of Staphylococcus aureus, S. epidermidis, Streptococcus pyogenes and Enterococcus faecalis. The partially purified antimicrobial molecule was found to be resistant to extremes of pH and temperatures and also to higher concentrations of trypsin and proteinase K. The antimicrobial molecule was purified by a three-step method that included reversed-phase high performance liquid chromatography (RP-HPLC). The minimum inhibitory concentration (MIC) values were determined for 14 species of bacteria using a microbroth dilution technique. The HPLC-purified fraction showed the MICs ranging from 0.5 to 16 μg/ml for methicillin and vancomycin-resistant Staphylococcus aureus (MVRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE) strains. The molecular mass of the antimicrobial compound was determined to be 842.37 Da. The same antimicrobial fraction showed negligible haemolytic activity against human red blood cells even at a concentration as high as 100 μg/ml. Because of its significant antimicrobial activity at low MIC values coupled with its non-haemolytic property, it may prove to be a novel antimicrobial lead molecule. PMID:26696963

  14. Emergence of Lamivudine-Resistant HBV during Antiretroviral Therapy Including Lamivudine for Patients Coinfected with HIV and HBV in China

    PubMed Central

    Li, Yijia; Zhu, Ting; Song, Xiaojing; Huang, Ying; Yang, Feifei; Guan, Shuo; Xie, Jing; Gohda, Jin; Hosoya, Noriaki; Kawana-Tachikawa, Ai; Liu, Wenjun; Gao, George Fu; Iwamoto, Aikichi; Li, Taisheng; Ishida, Takaomi

    2015-01-01

    In China, HIV-1-infected patients typically receive antiretroviral therapy (ART) that includes lamivudine (3TC) as a reverse-transcriptase inhibitor (RTI) (ART-3TC). Previous studies from certain developed countries have shown that, in ART-3TC, 3TC-resistant HBV progressively emerges at an annual rate of 15–20% in patients coinfected with HIV-1 and HBV. This scenario in China warrants investigation because >10% of all HIV-infected patients in China are HBV carriers. We measured the occurrence of 3TC-resistant HBV during ART-3TC for HIV-HBV coinfection and also tested the effect of tenofovir disoproxil fumarate (TDF) used as an additional RTI (ART-3TC/TDF) in a cohort study in China. We obtained 200 plasma samples collected from 50 Chinese patients coinfected with HIV-1 and HBV (positive for hepatitis B surface antigen) and examined them for the prevalence of 3TC-resistant HBV by directly sequencing PCR products that covered the HBV reverse-transcriptase gene. We divided the patients into ART-3TC and ART-3TC/TDF groups and compared the efficacy of treatment and incidence of drug-resistance mutation between the groups. HIV RNA and HBV DNA loads drastically decreased in both ART-3TC and ART-3TC/TDF groups. In the ART-3TC group, HBV breakthrough or insufficient suppression of HBV DNA loads was observed in 20% (10/50) of the patients after 96-week treatment, and 8 of these patients harbored 3TC-resistant mutants. By contrast, neither HBV breakthrough nor treatment failure was recorded in the ART-3TC/TDF group. All of the 3TC-resistant HBV mutants emerged from the cases in which HBV DNA loads were high at baseline. Our results clearly demonstrated that ART-3TC is associated with the emergence of 3TC-resistant HBV in patients coinfected with HIV-1 and HBV and that ART-3TC/TDF reduces HBV DNA loads to an undetectable level. These findings support the use of TDF-based treatment regimens for patients coinfected with HIV-1 and HBV. PMID:26288093

  15. Nationally representative equations that include resistance and reactance for the prediction of percent body fat in Americans.

    PubMed

    Stevens, J; Truesdale, K P; Cai, J; Ou, F-S; Reynolds, K R; Heymsfield, S B

    2017-07-24

    Resistance and reactance collected by bioelectrical impedance (BIA) can be used in equations to estimate percent body fat at relatively low cost and subject burden. To our knowledge, no such equations have been developed in a nationally representative sample. Dual-energy X-ray absorptiometry assessed percent body fat from the 1999 to 2004 National Health and Nutrition Survey was the criterion method for development of sex-specific percent body fat equations using up to 6467 males or 4888 females 8-49 years of age. Candidate variables were studied in multiple mathematical forms and interactions using the Least Absolute Shrinkage and Selection Operator. Models were fit in 2/3's of the data and validated in 1/3 of the data selected at random. Final coefficients, R(2) values and root mean square error (RMSE) were estimated in the full data set. Models that included age, ethnicity, height, weight, BMI and BIA assessments (resistance, reactance and height(2)/resistance) had R(2) values of 0.831 in men and 0.864 in women in the full data set. RMSE measurements were between 2 and 3 body fat percentage points, and all equations showed low bias across groups formed by age, race/ethnicity or body mass index category. The addition of triceps skinfold and waist circumference increased the R(2) to 0.905 in males and 0.883 in females. Adding other anthropometrics (plus menses in females) had little impact on performance. Reactance and resistance alone (in multiple mathematical forms) performed poorly with R(2)~0.2. Equations that included BIA assessments along with demographic and anthropometric variables provided percent body fat assessments that had high generalizability, strong predictive ability and low bias.International Journal of Obesity advance online publication, 15 August 2017; doi:10.1038/ijo.2017.167.

  16. Extended MHD Effects in High Energy Density Experiments

    NASA Astrophysics Data System (ADS)

    Seyler, Charles

    2016-10-01

    The MHD model is the workhorse for computational modeling of HEDP experiments. Plasma models are inheritably limited in scope, but MHD is expected to be a very good model for studying plasmas at the high densities attained in HEDP experiments. There are, however, important ways in which MHD fails to adequately describe the results, most notably due to the omission of the Hall term in the Ohm's law (a form of extended MHD or XMHD). This talk will discuss these failings by directly comparing simulations of MHD and XMHD for particularly relevant cases. The methodology is to simulate HEDP experiments using a Hall-MHD (HMHD) code based on a highly accurate and robust Discontinuous Galerkin method, and by comparison of HMHD to MHD draw conclusions about the impact of the Hall term. We focus on simulating two experimental pulsed power machines under various scenarios. We examine the MagLIF experiment on the Z-machine at Sandia National Laboratories and liner experiments on the COBRA machine at Cornell. For the MagLIF experiment we find that power flow in the feed leads to low density plasma ablation into the region surrounding the liner. The inflow of this plasma compresses axial magnetic flux onto the liner. In MHD this axial flux tends to resistively decay, whereas in HMHD a force-free current layer sustains the axial flux on the liner leading to a larger ratio of axial to azimuthal flux. During the liner compression the magneto-Rayleigh-Taylor instability leads to helical perturbations due to minimization of field line bending. Simulations of a cylindrical liner using the COBRA machine parameters can under certain conditions exhibit amplification of an axial field due to a force-free low-density current layer separated by some distance from the liner. This results in a configuration in which there is predominately axial field on the liner inside the current layer and azimuthal field outside the layer. We are currently attempting to experimentally verify the simulation

  17. Corrosion and arc erosion in MHD channels

    NASA Astrophysics Data System (ADS)

    Rosa, R. J.; Pollina, R. J.

    1991-10-01

    The objective of this task is to study the corrosion and arc erosion of MHD materials in a cooperative effort with, and to support, the MHD topping cycle program. Materials tested in the Avco Research Laboratory/Textron facility, or materials which have significant MHD importance, will be analyzed to document their physical deterioration. Conclusions shall be drawn about their wear mechanisms and lifetime in the MHD environment with respect to the following issues; sulfur corrosion, electrochemical corrosion, and arc erosion. The impact of any materials or slag conditions on the level of power output and on the level of leakage current in the MHD channel will also be noted, where appropriate.

  18. MHD-EMP protection guidelines

    SciTech Connect

    Barnes, P.R.; Vance, E.F.

    1992-03-01

    A nuclear detonation at altitudes several hundred kilometers above the earth will severely distort the earth`s magnetic field and result in a strong magnetohyrodynamic electromagnetic pulse (MHD-EMP). The geomagnetic disturbance interacts with the soil to induce current and horizontal electric gradients. The geomagnetic disturbance interacts with the soil to induced current and horizontal electric gradients in the earth. MHD-EMP, also called E3 since it is the third component of the high-altitude EMP (HEMP), lasts over 100 s after the exoatmospheric burst. MHD-EMP is similar to solar geomagnetic storms in it`s global and low frequency (less than 1 Hz) nature except that E3 can be much more intense with a far shorter duration. When the MHD-EMP gradients are integrated over great distances by power lines, communication cables, or other long conductors, the induced voltages are significant. (The horizontal gradients in the soil are too small to induce major responses by local interactions with facilities.) The long pulse waveform for MHD-EMP-induced currents on long lines has a peak current of 200 A and a time-to-half-peak of 100 s. If this current flows through transformer windings, it can saturate the magnetic circuit and cause 60 Hz harmonic production. To mitigate the effects of MHD-EMP on a facility, long conductors must be isolated from the building and the commercial power harmonics and voltage swings must be addressed. The transfer switch would be expected to respond to the voltage fluctuations as long as the harmonics have not interfered with the switch control circuitry. The major sources of MHD-EMP induced currents are the commercial power lines and neutral; neutral current indirect coupling to the facility power or ground system via the metal fence, powered gate, parking lights, etc; metal water pipes; phone lines; and other long conductors that enter or come near the facility. The major source of harmonics is the commercial power system.

  19. Outline of fast analyzer for MHD equilibrium FAME

    NASA Astrophysics Data System (ADS)

    Sakata, Shinya; Haginoya, Hirofumi; Tsuruoka, Takuya; Aoyagi, Tetsuo; Saito, Naoyuki; Harada, Hiroo; Tani, Keiji; Watanabe, Hideto

    1994-02-01

    The FAME (Fast Analyzer for Magnetohydrodynamic (MHD) Equilibrium) system has been developed in order to provide more than 100 MHD equilibria in time series which are enough for the non-stationary analysis of the experimental data of JT-60 within about 20 minutes shot interval. The FAME is an MIMD type small scale parallel computer with 20 microprocessors which are connected by a multi-stage switching system. The maximum theoretical speed is 250 MFLOPS. For the software system of FAME, MHD equilibrium analysis code SELENE and its input data production code FBI are tuned up taking the parallel processing into consideration. Consequently, the computational performance of the FAME system becomes more than 7 times faster than the existing general purpose computer FACOM M780-10s. This report summarizes the outline of the FAME system including hardware, soft-ware and peripheral equipments.

  20. Common Hamiltonian and topological properties of extended MHD models

    NASA Astrophysics Data System (ADS)

    Miloshevich, George; Lingam, Manasvi; Morrison, Philip

    2016-10-01

    Extended MHD, a 1-fluid model endowed with 2-fluid effects (electron inertia and Hall drift) possesses a Hamiltonian structure. This formulation is described, as it unifies different classes of extended MHD models (including those that have mutually exclusive effects). The unification is further highlighted by showing that these models possess common topological invariants that are the generalizations of the fluid/magnetic helicity. They can be expressed naturally in a knot-theoretic framework via the Jones polynomial by exploiting techniques from Chern-Simons theory. It is also shown that extended MHD exhibits other commonalities such as: generalized Kelvin circulation theorems, and the existence of two Lie-dragged 2-forms closely connected with generalizations of the fluid vorticity. NSF Grant No. AGS-133894, DOE Grants No. DE-AC02-09CH-11466 and DE-FG02-04ER-54742.

  1. Intensive lifestyle intervention including high-intensity interval training program improves insulin resistance and fasting plasma glucose in obese patients.

    PubMed

    Marquis-Gravel, Guillaume; Hayami, Douglas; Juneau, Martin; Nigam, Anil; Guilbeault, Valérie; Latour, Élise; Gayda, Mathieu

    2015-01-01

    To analyze the effects of a long-term intensive lifestyle intervention including high-intensity interval training (HIIT) and Mediterranean diet (MedD) counseling on glycemic control parameters, insulin resistance and β-cell function in obese subjects. The glycemic control parameters (fasting plasma glucose, glycated hemoglobin), insulin resistance, and β-cell function of 72 obese subjects (54 women; mean age = 53 ± 9 years) were assessed at baseline and upon completion of a 9-month intensive lifestyle intervention program conducted at the cardiovascular prevention and rehabilitation center of the Montreal Heart Institute, from 2009 to 2012. The program included 2-3 weekly supervised exercise training sessions (HIIT and resistance exercise), combined to MedD counseling. Fasting plasma glucose (FPG) (mmol/L) (before: 5.5 ± 0.9; after: 5.2 ± 0.6; P < 0.0001), fasting insulin (pmol/L) (before: 98 ± 57; after: 82 ± 43; P = 0.003), and insulin resistance, as assessed by the HOMA-IR score (before: 3.6 ± 2.5; after: 2.8 ± 1.6; P = 0.0008) significantly improved, but not HbA1c (%) (before: 5.72 ± 0.55; after: 5.69 ± 0.39; P = 0.448), nor β-cell function (HOMA-β, %) (before: 149 ± 78; after: 144 ± 75; P = 0.58). Following a 9-month intensive lifestyle intervention combining HIIT and MedD counseling, obese subjects experienced significant improvements of FPG and insulin resistance. This is the first study to expose the effects of a long-term program combining HIIT and MedD on glycemic control parameters among obese subjects.

  2. Intensive lifestyle intervention including high-intensity interval training program improves insulin resistance and fasting plasma glucose in obese patients☆

    PubMed Central

    Marquis-Gravel, Guillaume; Hayami, Douglas; Juneau, Martin; Nigam, Anil; Guilbeault, Valérie; Latour, Élise; Gayda, Mathieu

    2015-01-01

    Objectives To analyze the effects of a long-term intensive lifestyle intervention including high-intensity interval training (HIIT) and Mediterranean diet (MedD) counseling on glycemic control parameters, insulin resistance and β-cell function in obese subjects. Methods The glycemic control parameters (fasting plasma glucose, glycated hemoglobin), insulin resistance, and β-cell function of 72 obese subjects (54 women; mean age = 53 ± 9 years) were assessed at baseline and upon completion of a 9-month intensive lifestyle intervention program conducted at the cardiovascular prevention and rehabilitation center of the Montreal Heart Institute, from 2009 to 2012. The program included 2–3 weekly supervised exercise training sessions (HIIT and resistance exercise), combined to MedD counseling. Results Fasting plasma glucose (FPG) (mmol/L) (before: 5.5 ± 0.9; after: 5.2 ± 0.6; P < 0.0001), fasting insulin (pmol/L) (before: 98 ± 57; after: 82 ± 43; P = 0.003), and insulin resistance, as assessed by the HOMA-IR score (before: 3.6 ± 2.5; after: 2.8 ± 1.6; P = 0.0008) significantly improved, but not HbA1c (%) (before: 5.72 ± 0.55; after: 5.69 ± 0.39; P = 0.448), nor β-cell function (HOMA-β, %) (before: 149 ± 78; after: 144 ± 75; P = 0.58). Conclusion Following a 9-month intensive lifestyle intervention combining HIIT and MedD counseling, obese subjects experienced significant improvements of FPG and insulin resistance. This is the first study to expose the effects of a long-term program combining HIIT and MedD on glycemic control parameters among obese subjects. PMID:26844086

  3. American Bullfrogs (Lithobates catesbeianus) Resist Infection by Multiple Isolates of Batrachochytrium dendrobatidis, Including One Implicated in Wild Mass Mortality.

    PubMed

    Eskew, Evan A; Worth, S Joy; Foley, Janet E; Todd, Brian D

    2015-09-01

    The emerging amphibian disease chytridiomycosis varies in severity depending on host species. Within species, disease susceptibility can also be influenced by pathogen variation and environmental factors. Here, we report on experimental exposures of American bullfrogs (Lithobates catesbeianus) to three different isolates of Batrachochytrium dendrobatidis (Bd), including one implicated in causing mass mortality of wild American bullfrogs. Exposed frogs showed low infection prevalence, relatively low infection load, and lack of clinical disease. Our results suggest that environmental cofactors are likely important contributors to Bd-associated American bullfrog mortality and that this species both resists and tolerates Bd infection.

  4. MHD Simulations of the Plasma Flow in the Magnetic Nozzle

    NASA Technical Reports Server (NTRS)

    Smith, T. E. R.; Keidar, M.; Sankaran, K.; olzin, K. A.

    2013-01-01

    The magnetohydrodynamic (MHD) flow of plasma through a magnetic nozzle is simulated by solving the governing equations for the plasma flow in the presence of an static magnetic field representing the applied nozzle. This work will numerically investigate the flow and behavior of the plasma as the inlet plasma conditions and magnetic nozzle field strength are varied. The MHD simulations are useful for addressing issues such as plasma detachment and to can be used to gain insight into the physical processes present in plasma flows found in thrusters that use magnetic nozzles. In the model, the MHD equations for a plasma, with separate temperatures calculated for the electrons and ions, are integrated over a finite cell volume with flux through each face computed for each of the conserved variables (mass, momentum, magnetic flux, energy) [1]. Stokes theorem is used to convert the area integrals over the faces of each cell into line integrals around the boundaries of each face. The state of the plasma is described using models of the ionization level, ratio of specific heats, thermal conductivity, and plasma resistivity. Anisotropies in current conduction due to Hall effect are included, and the system is closed using a real-gas equation of state to describe the relationship between the plasma density, temperature, and pressure.A separate magnetostatic solver is used to calculate the applied magnetic field, which is assumed constant for these calculations. The total magnetic field is obtained through superposition of the solution for the applied magnetic field and the self-consistently computed induced magnetic fields that arise as the flowing plasma reacts to the presence of the applied field. A solution for the applied magnetic field is represented in Fig. 1 (from Ref. [2]), exhibiting the classic converging-diverging field pattern. Previous research was able to demonstrate effects such as back-emf at a super-Alfvenic flow, which significantly alters the shape of the

  5. Global MHD Simulations of Space Plasma Environments: Heliosphere, Comets, Magnetospheres of Plants and Satellites

    NASA Technical Reports Server (NTRS)

    Kabin, K.; Hansen, K. C.; Gombosi, T. I.; Combi, M. R.; Linde, T. J.; DeZeeuw, D. L.; Groth, C. P. T.; Powell, K. G.; Nagy, A. F.

    2000-01-01

    Magnetohydrodynamics (MHD) provides an approximate description of a great variety of processes in space physics. Accurate numerical solutions of the MHD equations are still a challenge, but in the past decade a number of robust methods have appeared. Once these techniques made the direct solution of MHD equations feasible, a number of global three-dimensional models were designed and applied to many space physics objects. The range of these objects is truly astonishing, including active galactic nuclei, the heliosphere, the solar corona, and the solar wind interaction with planets, satellites, and comets. Outside the realm of space physics, MHD theory has been applied to such diverse problems as laboratory plasmas and electromagnetic casting of liquid metals. In this paper we present a broad spectrum of models of different phenomena in space science developed in the recent years at the University of Michigan. Although the physical systems addressed by these models are different, they all use the MHD equations as a unifying basis.

  6. Magnetohydrodynamic (MHD) Magnet Modeling

    DTIC Science & Technology

    1979-06-01

    quench initiated. This peak temper- ature cannnt exceed the melting point of solder, approximately 480 K. The vol- tage drop across the resistive region...solder melting point . The best method of reducing the maximum temperatures in the magnet systems is to increase the spread of the normal region. The same...Tangent crossover points 5 Inlet field-. \\ Slope must exceed/’- 110T/mifrom -a 3either tangent S- .. .. . ...... __crossover point 4. Outlet 7u field •2_ E

  7. Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis.

    PubMed

    Phillips, Joshua B; Smith, Adrienne E; Kusche, Brian R; Bessette, Bradley A; Swain, P Whitney; Bergmeier, Stephen C; McMills, Mark C; Wright, Dennis L; Priestley, Nigel D

    2010-10-01

    We have shown that the intentional engineering of a natural product biosynthesis pathway is a useful way to generate stereochemically complex scaffolds for use in the generation of combinatorial libraries that capture the structural features of both natural products and synthetic compounds. Analysis of a prototype library based upon nonactic acid lead to the discovery of triazole-containing nonactic acid analogs, a new structural class of antibiotic that exhibits bactericidal activity against drug resistant, Gram-positive pathogens including Staphylococcus aureus and Enterococcus faecalis.

  8. Resistive MHD simulations in support of SSPX

    NASA Astrophysics Data System (ADS)

    Hooper, E. B.; Cohen, B. I.; Lodestro, L. L.; Sovinec, C. R.

    2006-04-01

    The SSPX spheromak has obtained Btor>0.6T, Te=350eV and t(pulse) 3ms. NIMROD simulations are used to interpret results, guide experiments, and explore upgrades. Voltage spikes during formation and sustainment are interpreted as reconnection across an n=1, negative-current layer close to the mean-field x-point. Field lines are chaotic during these events, causing rapid electron energy loss to the walls; Te<50eV in experiment and simulation during strong helicity injection. Sustainment occurs at a high ratio of gun current to bias flux. During slow plasma decay at low gun current, high Te results when magnetic fluctuations are low (<1%). If q crosses low-order rational surfaces, islands form causing reduced energy confinement. Fieldlines can become chaotic (Lyapanov length > 4πR); if they reach walls Te drops to <50eV. Changing Zeff=1 to 2.3 (SSPX value) increases ohmic heating and decreases parallel thermal conduction, affecting spheromak evolution. An experimental upgrade to allow bias field reduction following formation may allow increased efficiency operation.

  9. MHD control in burning plasmas MHD control in burning plasmas

    NASA Astrophysics Data System (ADS)

    Donné, Tony; Liang, Yunfeng

    2012-07-01

    Fusion physics focuses on the complex behaviour of hot plasmas confined by magnetic fields with the ultimate aim to develop a fusion power plant. In the future generation of tokamaks like ITER, the power generated by the fusion reactions substantially exceeds the external input power (Pfusion}/Pin >= 10). When this occurs one speaks of a burning plasma. Twenty per cent of the generated fusion power in a burning plasma is carried by the charged alpha particles, which transfer their energy to the ambient plasma in collisions, a process called thermalization. A new phenomenon in burning plasmas is that the alpha particles, which form a minority but carry a large fraction of the plasma kinetic energy, can collectively drive certain types of magneto-hydrodynamic (MHD) modes, while they can suppress other MHD modes. Both types of MHD modes can have desirable effects on the plasma, as well as be detrimental to the plasma. For example, the so-called sawtooth instability, on the one hand, is largely responsible for the transport of the thermalized alpha particles out of the core, but, on the other hand, may result in the loss of the energetic alphas before they have fully thermalized. A further undesirable effect of the sawtooth instability is that it may trigger other MHD modes such as neoclassical tearing modes (NTMs). These NTMs, in turn, are detrimental to the plasma confinement and in some cases may even lead to disruptive termination of the plasma. At the edge of the plasma, finally, so-called edge localized modes or ELMs occur, which result in extremely high transient heat and particle loads on the plasma-facing components of a reactor. In order to balance the desired and detrimental effects of these modes, active feedback control is required. An additional complication occurs in a burning plasma as the external heating power, which is nowadays generally used for plasma control, is small compared to the heating power of the alpha particles. The scientific challenge

  10. A kinetic-MHD model for low frequency phenomena

    SciTech Connect

    Cheng, C.Z.

    1991-07-01

    A hybrid kinetic-MHD model for describing low-frequency phenomena in high beta anisotropic plasmas that consist of two components: a low energy core component and an energetic component with low density. The kinetic-MHD model treats the low energy core component by magnetohydrodynamic (MHD) description, the energetic component by kinetic approach such as the gyrokinetic equation, and the coupling between the dynamics of these two components through plasma pressure in the momentum equation. The kinetic-MHD model optimizes both the physics contents and the theoretical efforts in studying low frequency MHD waves and transport phenomena in general magnetic field geometries, and can be easily modified to include the core plasma kinetic effects if necessary. It is applicable to any magnetized collisionless plasma system where the parallel electric field effects are negligibly small. In the linearized limit two coupled eigenmode equations for describing the coupling between the transverse Alfven type and the compressional Alfven type waves are derived. The eigenmode equations are identical to those derived from the full gyrokinetic equation in the low frequency limit and were previously analyzed both analytically nd numerically to obtain the eigenmode structure of the drift mirror instability which explains successfully the multi-satellite observation of antisymmetric field-aligned structure of the compressional magnetic field of Pc 5 waves in the magnetospheric ring current plasma. Finally, a quadratic form is derived to demonstrate the stability of the low-frequency transverse and compressional Alfven type instabilities in terms of the pressure anisotropy parameter {tau} and the magnetic field curvature-pressure gradient parameter. A procedure for determining the stability of a marginally stable MHD wave due to wave-particle resonances is also presented.

  11. Adaptive Numerical Dissipative Control in High Order Schemes for Multi-D Non-Ideal MHD

    NASA Technical Reports Server (NTRS)

    Yee, H. C.; Sjoegreen, B.

    2004-01-01

    The goal is to extend our adaptive numerical dissipation control in high order filter schemes and our new divergence-free methods for ideal MHD to non-ideal MHD that include viscosity and resistivity. The key idea consists of automatic detection of different flow features as distinct sensors to signal the appropriate type and amount of numerical dissipation/filter where needed and leave the rest of the region free of numerical dissipation contamination. These scheme-independent detectors are capable of distinguishing shocks/shears, flame sheets, turbulent fluctuations and spurious high-frequency oscillations. The detection algorithm is based on an artificial compression method (ACM) (for shocks/shears), and redundant multi-resolution wavelets (WAV) (for the above types of flow feature). These filter approaches also provide a natural and efficient way for the minimization of Div(B) numerical error. The filter scheme consists of spatially sixth order or higher non-dissipative spatial difference operators as the base scheme for the inviscid flux derivatives. If necessary, a small amount of high order linear dissipation is used to remove spurious high frequency oscillations. For example, an eighth-order centered linear dissipation (AD8) might be included in conjunction with a spatially sixth-order base scheme. The inviscid difference operator is applied twice for the viscous flux derivatives. After the completion of a full time step of the base scheme step, the solution is adaptively filtered by the product of a 'flow detector' and the 'nonlinear dissipative portion' of a high-resolution shock-capturing scheme. In addition, the scheme independent wavelet flow detector can be used in conjunction with spatially compact, spectral or spectral element type of base schemes. The ACM and wavelet filter schemes using the dissipative portion of a second-order shock-capturing scheme with sixth-order spatial central base scheme for both the inviscid and viscous MHD flux

  12. Magnetic levitation and MHD propulsion

    NASA Astrophysics Data System (ADS)

    Tixador, P.

    1994-04-01

    Magnetic levitation and MHD propulsion are now attracting attention in several countries. Different superconducting MagLev and MHD systems will be described concentrating on, above all, the electromagnetic aspect. Some programmes occurring throughout the world will be described. Magnetic levitated trains could be the new high speed transportation system for the 21st century. Intensive studies involving MagLev trains using superconductivity have been carried out in Japan since 1970. The construction of a 43 km long track is to be the next step. In 1991 a six year programme was launched in the United States to evaluate the performances of MagLev systems for transportation. The MHD (MagnetoHydroDynamic) offers some interesting advantages (efficiency, stealth characteristics, ...) for naval propulsion and increasing attention is being paid towards it nowadays. Japan is also up at the top with the tests of Yamato I, a 260 ton MHD propulsed ship. Depuis quelques années nous assistons à un redémarrage de programmes concernant la lévitation et la propulsion supraconductrices. Différents systèmes supraconducteurs de lévitation et de propulsion seront décrits en examinant plus particulièrement l'aspect électromagnétique. Quelques programmes à travers le monde seront abordés. Les trains à sustentation magnétique pourraient constituer un nouveau mode de transport terrestre à vitesse élevée (500 km/h) pour le 21^e siècle. Les japonais n'ont cessé de s'intéresser à ce système avec bobine supraconductrice. Ils envisagent un stade préindustriel avec la construction d'une ligne de 43 km. En 1991 un programme américain pour une durée de six ans a été lancé pour évaluer les performances des systèmes à lévitation pour le transport aux Etats Unis. La MHD (Magnéto- Hydro-Dynamique) présente des avantages intéressants pour la propulsion navale et un regain d'intérêt apparaît à l'heure actuelle. Le japon se situe là encore à la pointe des d

  13. Thiamine induced resistance to Plasmopara viticola in grapevine and elicited host-defense responses, including HR like-cell death.

    PubMed

    Boubakri, Hatem; Wahab, Mohamed Ali; Chong, Julie; Bertsch, Christophe; Mliki, Ahmed; Soustre-Gacougnolle, Isabelle

    2012-08-01

    Recently, thiamine (VitaminB1) has been shown to induce resistance against Pseudomonas syringae in Arabidopsis plants through priming of defense responses. In this paper, we have demonstrated the efficiency of thiamine to induce resistance against downy mildew caused by the oomycete Plasmopara viticola in a susceptible Vitis vinifera cultivar "Chardonnay" under glasshouse controlled conditions by providing a dual mode of action involving direct antifungal activity and elicitation of host-defense responses. Thiamine-induced defense responses included the generation of hydrogen peroxide (H(2)O(2)) in both grapevine suspension cultured cells (SCC) and plant leaves, upregulation of an array of defense-related genes and the induction of other defense responses at subcellular level such as callose deposition in stomata cells, phenolic compounds accumulation and hypersensitive response (HR) like-cell death. Epifluorescence microscopy studies revealed dramatic changes in P. viticola individual developmental stages during its colonization of the intercellular space of the leaf mesophyll in thiamine-treated plants. Collectively, our report evidenced the efficiency of thiamine in the control of downy mildew in grapevine by direct and indirect effects, suggesting that thiamine could be an attractive alternative to chemical fungicides in disease management in vineyards. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  14. GRADSPMHD: A parallel MHD code based on the SPH formalism

    NASA Astrophysics Data System (ADS)

    Vanaverbeke, S.; Keppens, R.; Poedts, S.

    2014-03-01

    We present GRADSPMHD, a completely Lagrangian parallel magnetohydrodynamics code based on the SPH formalism. The implementation of the equations of SPMHD in the “GRAD-h” formalism assembles known results, including the derivation of the discretized MHD equations from a variational principle, the inclusion of time-dependent artificial viscosity, resistivity and conductivity terms, as well as the inclusion of a mixed hyperbolic/parabolic correction scheme for satisfying the ∇ṡB→ constraint on the magnetic field. The code uses a tree-based formalism for neighbor finding and can optionally use the tree code for computing the self-gravity of the plasma. The structure of the code closely follows the framework of our parallel GRADSPH FORTRAN 90 code which we added previously to the CPC program library. We demonstrate the capabilities of GRADSPMHD by running 1, 2, and 3 dimensional standard benchmark tests and we find good agreement with previous work done by other researchers. The code is also applied to the problem of simulating the magnetorotational instability in 2.5D shearing box tests as well as in global simulations of magnetized accretion disks. We find good agreement with available results on this subject in the literature. Finally, we discuss the performance of the code on a parallel supercomputer with distributed memory architecture. Catalogue identifier: AERP_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AERP_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 620503 No. of bytes in distributed program, including test data, etc.: 19837671 Distribution format: tar.gz Programming language: FORTRAN 90/MPI. Computer: HPC cluster. Operating system: Unix. Has the code been vectorized or parallelized?: Yes, parallelized using MPI. RAM: ˜30 MB for a

  15. Integral Constraints and MHD Stability

    NASA Astrophysics Data System (ADS)

    Jensen, T. H.

    2003-10-01

    Determining stability of a plasma in MHD equilibrium, energetically isolated by a conducting wall, requires an assumption on what governs the dynamics of the plasma. One example is the assumption that the plasma obeys ideal MHD, leading to the well known ``δ W" criteria [I. Bernstein, et al., Proc. Roy. Soc. London A244, 17 (1958)]. A radically different approach was used by Taylor [J.B. Taylor, Rev. Mod. Phys. 58, 741 (1986)] in assuming that the dynamics of the plasma is restricted only by the requirement that helicity, an integral constant associated with the plasma, is conserved. The relevancy of Taylor's assumption is supported by the agreement between resulting theoretical results and experimental observations. Another integral constraint involves the canonical angular momentum of the plasma particles. One consequence of using this constraint is that tokamak plasmas have no poloidal current in agreement with some current hole tokamak observations [T.H. Jensen, Phys. Lett. A 305, 183 (2002)].

  16. Extended MHD simulation of resonant magnetic perturbations

    NASA Astrophysics Data System (ADS)

    Strauss, H. R.; Sugiyama, L.; Park, G. Y.; Chang, C. S.; Ku, S.; Joseph, I.

    2009-05-01

    Resonant magnetic perturbations (RMPs) have been found effective in suppressing edge localized modes (ELMs) in the DIII-D experiment (Evans et al 2006 Phys. Plasmas 13 056121, Moyer et al 2005 Phys. Plasmas 12 056119). Simulations with the M3D initial value code indicate that plasma rotation, due to an MHD toroidal rotation or to two-fluid drifts, has an essential effect on the RMP. When the flow is below a threshold, the RMP field can couple to a resistive mode with a helical structure, different from the usual ELM, that amplifies the non-axisymmetric field. The magnetic field becomes stochastic in the outer part of the plasma, causing density and temperature loss. At higher rotation speed, the resistive mode is stabilized and the applied RMP is screened from the plasma, so that the stochastic magnetic layer is thinner and the temperature remains similar to the initial unperturbed state. The rotational flow effects, along with the remnants of the screened RMP, cause a density loss which extends into the plasma core. The two-fluid model contains intrinsic drift motion and axisymmetric toroidal rotation may not be needed to screen the RMP nor stabilize the resistive mode.

  17. Operational analysis of open-cycle MHD

    NASA Astrophysics Data System (ADS)

    Lippert, T. E.; McCutchan, D. A.

    1980-07-01

    Open cycle magnetohydrodynamic (OCMHD) conceptual power plant designs are studied in the context of a utility system to form a better basis for understanding their design, design requirements, and market possibilities. Based on assumed or projected plant costs and performance characteristics, assumed economics and escalation factors, and one coal supply and delivery scenario, overall and regional OCMHD utility market possibilities are reviewed. Additionally, for one hypothetical utility system a generation expansion plan is developed that includes OCMHD as a baseload power generating station. The impact on generation system economics and operation of alternating selected MHD plant cost and performance characteristics is reviewed. Baseload plant availability is shown as an important plant design consideration, and a general methodology and data base is developed to assess the impact on design and cost of various reliability decisions. An overall plant availability goal is set and the required availabilities of various MHD high technology components are derived to meet the plant goal. The approach is then extended to projecting channel life goals for various plant design configurations and assumptions.

  18. Design of selection schemes to include tick resistance in the breeding goal for Hereford and Braford cattle.

    PubMed

    Reis, Â P; Boligon, A A; Yokoo, M J; Cardoso, F F

    2017-02-01

    scenario to form tick-resistant lines in Hereford and Braford cattle. However, with 50% relative weight for TC, including GEBV information for TC only or for all traits in index ( = 0.9), it should yield 93 or 84% of RS, respectively, compared to that obtained with full emphasis on TC (100% relative weight) and GEBV information. This indicates that in the presence of highly accurate GEBV, despite slightly slower gain for TC, indexes with 50% relative weight for TC are interesting alternatives to jointly improve tick resistance and other relevant traits.

  19. Metal/gas MHD conversion

    NASA Astrophysics Data System (ADS)

    Thibault, J. P.; Joussellin, F.; Alemany, A.; Dupas, A.

    1982-09-01

    Operation features, theory, performance, and possible spatial applications of metal/gas MHD electrical generators are described. The working principle comprises an MHD channel, surrounded by a magnet, filled with a molten, highly conductive metal into which gas is pumped. The heat of the metal expands the gas, forcing a flow through the magnetic field crossing the channel, thus creating an electrical current conducted by the metal. The gas and metal are separated by a centrifugal device and both are redirected into the channel, forming thereby a double closed circuit when the heat of the molten metal is returned to the flow. Necessary characteristics for the gas such as a fairly low vaporization temperature and nonmiscibility with the metal, are outlined, and a space system using Li-Cs or Z-K as the heat carrier kept molten by a parabolic dish system is sketched. Equations governing the fluid mechanics, thermodynamics, and the electrical generation are defined. The construction of a prototype MHD generator using a tin-water flow operating at 250 C, a temperature suitable for coupling to solar heat sources, is outlined, noting expected efficiencies of 20-30 percent.

  20. Stabilization of the external kink and other MHD issues. Summary report

    SciTech Connect

    Freidberg, J.P.; Goldston, R.J.; Jardin, S.C.; Neilson, G.H.; Rosenbluth, M.N.; Taylor, T.S.; Thomassen, K.I.

    1993-08-13

    An MHD workshop entitled ``Stabilization of the External Kink and Other MHD Issues`` was held June 1993. This is a summary report of activities at that workshop, structured to respond to the three questions in the charge (letter from J. Willis). The experimental and theoretical status of these issues, and the R&D needs in each area, are addressed. We discuss the potential impact on the TPX and ITER programs of these issues. The workshop participants came from a broad and diverse range of institutions in the fusion program, including international participants. As a result, we believe the summary here reflects some consensus of the community on these very important program issues, and that the TPX and ITER programs will benefit from these discussions. The title of the workshop was chosen to indicate both our knowledge and our uncertainty of MHD phenomena limiting {beta} and causing disruptions in tokamaks. The purpose was to bring together theorists and experimentalist in order to assess our current understanding of the external kink instability at high {beta}, and to assess the potential for passive or active stabilization of the dominant modes. We also outlined the R&D needed for TPX and other future devices. Not only was the preworkshop theory clearly presented, but significant new theoretical results were described for the first time, emphasizing the roles of the resistivity of the cold edge plasma and of the plasma toroidicity in the stability criteria. Excellent reviews of the effects of the vessel walls on plasma stability were given as related to the DIII-D, TFTR, JET, PBX-M, and HBT-EP experiments. These results are generally consistent with the more complete theory.

  1. Sialon Electrodes and Insulators for MHD Device

    NASA Technical Reports Server (NTRS)

    Phillips, W. M.

    1984-01-01

    Rectangular magnetohydrodynamic (MHD) channel structure for electrical power generation designed using pure sialon ceramic for insulating portion of structure and metal-bearing sialon cermet for conducting portion.

  2. Rapporteur report: MHD electric power plants

    NASA Technical Reports Server (NTRS)

    Seikel, G. R.

    1980-01-01

    Five US papers from the Proceedings of the Seventh International Conference on MHD Electrical Power Generation at the Massachusetts Institute of Technology are summarized. Results of the initial parametric phase of the US effort on the study of potential early commercial MHD plants are reported and aspects of the smaller commercial prototype plant termed the Engineering Test Facility are discussed. The alternative of using a disk geometry generator rather than a linear generator in baseload MHD plants is examined. Closed-cycle as well as open-cycle MHD plants are considered.

  3. Is FDA-Approved Bevacizumab Cost-Effective When Included in the Treatment of Platinum-Resistant Recurrent Ovarian Cancer?

    PubMed

    Chappell, Nicole P; Miller, Caela R; Fielden, Aaron D; Barnett, Jason C

    2016-07-01

    Although the Food and Drug Administration has approved incorporation of bevacizumab (BEV) into the treatment of platinum-resistant ovarian cancer (PROC), cost-value measures are an essential consideration, as evidenced by the recent ASCO Value Framework initiative. We assessed the cost-effectiveness and reviewed the net health benefit (NHB) of this expensive treatment. A cost-effectiveness decision model was constructed using results from a phase III trial comparing BEV plus cytotoxic chemotherapy with chemotherapy alone in patients with PROC. The Avastin Use in Platinum-Resistant Epithelial Ovarian Cancer (AURELIA) trial demonstrated improvement in progression-free survival and quality of life in patients receiving BEV. Costs, paracentesis rates, and adverse events were incorporated, including subgroup analysis of different partner chemotherapy agents. Inclusion of BEV in the treatment of platinum-resistant recurrent ovarian cancer meets the common willingness-to-pay incremental cost-effectiveness ratio (ICER) threshold of $100,000 per progression-free life-year saved (LYS) for 15-mg/kg dosing and approaches this threshold for 10-mg/kg dosing, with an ICER of $160,000. In sensitivity analysis, reducing the cost of BEV by 13% (from $9,338 to $8,100 per cycle) allows 10-mg/kg dosing to reach a $100,000 ICER. Exploratory analysis of different BEV chemotherapy partners showed an ICER of $76,000 per progression-free LYS (6.5-month progression-free survival improvement) and $54,000 per LYS (9.1-month overall survival improvement) for the addition of BEV to paclitaxel once per week. Using the ASCO framework for value assessment, the NHB score for BEV plus paclitaxel once per week is 48. Using a willingness-to-pay threshold of $100,000 ICER, the addition of BEV to chemotherapy either demonstrates or approaches cost-effectiveness and NHB when added to the treatment of patients with PROC. Copyright © 2016 by American Society of Clinical Oncology.

  4. High-beta extended MHD simulations of stellarators

    NASA Astrophysics Data System (ADS)

    Bechtel, T. A.; Hegna, C. C.; Sovinec, C. R.; Roberds, N. A.

    2016-10-01

    The high beta properties of stellarator plasmas are studied using the nonlinear, extended MHD code NIMROD. In this work, we describe recent developments to the semi-implicit operator which allow the code to model 3D plasma evolution with better accuracy and efficiency. The configurations under investigation are an l=2, M=5 torsatron with geometry modeled after the Compact Toroidal Hybrid (CTH) experiment and an l=2, M=10 torsatron capable of having vacuum rotational transform profiles near unity. High-beta plasmas are created using a volumetric heating source and temperature dependent anisotropic thermal conduction and resistivity. To reduce computation expenses, simulations are initialized from stellarator symmetric pseudo-equilibria by turning on symmetry breaking modes at finite beta. The onset of MHD instabilities and nonlinear consequences are monitored as a function of beta as well as the fragility of the magnetic surfaces. Research supported by US DOE under Grant No. DE-FG02-99ER54546.

  5. 2D Numerical MHD Models of Solar Explosive Events

    NASA Astrophysics Data System (ADS)

    Roussev, I.

    2001-10-01

    Observations of the Sun reveal a great variety of dynamic phenomena interpretable as a manifestation of magnetic reconnection. These range from small-scale 'Explosive events' seen in the 'quiet' Sun, through violent flares observed in active regions. The high degree of complexity of the magnetic field inferred from observations may locally produce a fruitful environment for the process of magnetic reconnection to take place. Explosive events are associated with regions undergoing magnetic flux cancellation. This thesis presents a 2-dimensional (2D) numerical study devoted to explore the idea that the salient spectral signatures seen in explosive events are most probably caused by bi-directional outflow jets as a results of an ongoing magnetic reconnection. In order to provide qualitative results needed for the better physical interpretation of solar explosive events, several models intended to represent a 'quiet' Sun transition of solar explosive events, several models intended to represent a 'quiet' Sun transition region undergoing magnetic reconnection are examined, in both unstratified and gravitationally stratified atmospheres. The magnetic reconnection is initiated in an ad hoc manner, and the dynamic evolution is followed by numerically solving the equations of 2D dissipative magnetohydrodynamics (MHD), including the effects of field-aligned thermal conduction, radiative losses, volumetric heating, and anomalous resistivity.

  6. Region-Specific Diet-induced and Leptin-Induced Cellular Leptin Resistance Includes the Ventral Tegmental Area in Rats

    PubMed Central

    Matheny, M.; Shapiro, A.; Tümer, N.; Scarpace, P. J.

    2010-01-01

    Diet-induced obesity (DIO) results in region-specific cellular leptin resistance in the arcuate nucleus (ARC) of the hypothalamus in one strain of mice and in several medial basal hypothalamic regions in another. We hypothesized that the ventral tegmental area (VTA) is also likely susceptible to diet-induced and leptin-induced leptin resistance in parallel to that in hypothalamic areas. We examined two forms of leptin resistance in F344xBN rats, that induced by 6-months of high fat (HF) feeding and that induced by 15-months of central leptin overexpression by use of recombinant adeno-associated viral (rAAV)-mediated gene delivery of rat leptin. Cellular leptin resistance was assessed by leptin-stimulated phosphorylation of signal transducers and activators of transcription 3 (STAT3) in medial basal hypothalamic areas and the VTA. The regional pattern and degree of leptin resistance with HF was distinctly different than that with leptin overexpression. Chronic HF feeding induced a cellular leptin resistance that was identified in the ARC and VTA, but absent in the lateral hypothalamus (LH), ventromedial hypothalamus (VMH), and dorsomedial hypothalamus (DMH). In contrast, chronic central leptin overexpression induced cellular leptin resistance in all areas examined. The identification of leptin resistance in the VTA, in addition to the leptin resistance in the hypothalamus, provides one potential mechanism, underlying the increased susceptibility of leptin resistant rats to HF-induced obesity. PMID:21059361

  7. Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats.

    PubMed

    Matheny, M; Shapiro, A; Tümer, N; Scarpace, P J

    2011-01-01

    Diet-induced obesity (DIO) results in region-specific cellular leptin resistance in the arcuate nucleus (ARC) of the hypothalamus in one strain of mice and in several medial basal hypothalamic regions in another. We hypothesized that the ventral tegmental area (VTA) is also likely susceptible to diet-induced and leptin-induced leptin resistance in parallel to that in hypothalamic areas. We examined two forms of leptin resistance in F344xBN rats, that induced by 6-months of high fat (HF) feeding and that induced by 15-months of central leptin overexpression by use of recombinant adeno-associated viral (rAAV)-mediated gene delivery of rat leptin. Cellular leptin resistance was assessed by leptin-stimulated phosphorylation of signal transducers and activators of transcription 3 (STAT3) in medial basal hypothalamic areas and the VTA. The regional pattern and degree of leptin resistance with HF was distinctly different than that with leptin overexpression. Chronic HF feeding induced a cellular leptin resistance that was identified in the ARC and VTA, but absent in the lateral hypothalamus (LH), ventromedial hypothalamus (VMH), and dorsomedial hypothalamus (DMH). In contrast, chronic central leptin overexpression induced cellular leptin resistance in all areas examined. The identification of leptin resistance in the VTA, in addition to the leptin resistance in the hypothalamus, provides one potential mechanism, underlying the increased susceptibility of leptin resistant rats to HF-induced obesity.

  8. System study of an MHD/gas turbine combined-cycle baseload power plant. HTGL report No. 134

    SciTech Connect

    Annen, K.D.

    1981-08-01

    The MHD/gas turbine combined-cycle system has been designed specifically for applications where the availability of cooling water is very limited. The base case systems which were studied consisted of an MHD plant with a gas turbine bottoming plant, and required no cooling water. The gas turbine plant uses only air as its working fluid and receives its energy input from the MHD exhaust gases by means of metal tube heat exchangers. In addition to the base case systems, vapor cycle variation systems were considered which included the addition of a vapor cycle bottoming plant to improve the thermal efficiency. These systems required a small amount of cooling water. The MHD/gas turbine systems were modeled with sufficient detail, using realistic component specifications and costs, so that the thermal and economic performance of the system could be accurately determined. Three cases of MHD/gas turbine systems were studied, with Case I being similar to an MHD/steam system so that a direct comparison of the performances could be made, with Case II being representative of a second generation MHD system, and with Case III considering oxygen enrichment for early commercial applications. The systems are nominally 800 MW/sub e/ to 1000 MW/sub e/ in size. The results show that the MHD/gas turbine system has very good thermal and economic performances while requiring either little or no cooling water. Compared to the MHD/steam system which has a cooling tower heat load of 720 MW, the Base Case I MHD/gas turbine system has a heat rate which is 13% higher and a cost of electricity which is only 7% higher while requiring no cooling water. Case II results show that an improved performance can be expected from second generation MHD/gas turbine systems. Case III results show that an oxygen enriched MHD/gas turbine system may be attractive for early commercial applications in dry regions of the country.

  9. Coronal roots of solar wind streams: 3-D MHD modeling

    NASA Technical Reports Server (NTRS)

    Pisanko, Yu. V.

    1995-01-01

    Weak (discontinuous) solutions of the 3-D MHD equations look like a promising tool to model the transonic solar wind with structural elements: current sheets, coronal plumes etc. Using the observational information about various coronal emissions one can include these structural elements into the 3-D MHD solar wind model by embedding the discontinuities of given type. Such 3-D MHD structured solar wind is calculated self-consistently: variants are examined via numerical experiments. In particular, the behavior of coronal plumes in the transonic solar wind flow, is modeled. The input information for numerical modeling (for example, the magnetic field map at the very base of the solar corona) can be adjusted so that fast stream arises over the center of the coronal hole, over the coronal hole boundaries and, even, over the region with closed magnetic topology. 3-D MHD equations have the analytical solution which can serve as a model of supersonic trans-alfvenic solar wind in the (5-20) solar radii heliocentric distance interval. The transverse, nonradial total (gas + magnetic field) pressure balance in the flow is the corner-stone of this solution. The solution describes the filamentation (ray-like structure of the solar corona) and streaming (formation of high-speed streams with velocities up to 800 km/sec) as a consequence of the magnetic field spatial inhomogeneous structure and trans-alfvenic character of the flow. The magnetic field works in the model as a 'controller' for the solar wind streaming and filamentation.

  10. CME generated MHD shocks: creation, evolution and impact

    NASA Astrophysics Data System (ADS)

    Poedts, S.; van der Holst, B.; Chattopadhyay, I.; Shergelashvili, D.; Banerjee, D.; Deconinck, H.

    2003-04-01

    The shocks in the solar corona caused by fast Coronal Mass Ejections (CMEs) are studied in the framework of computational magnetohydrodynamics (MHD). Such MHD shocks can have a complicated structure including secondary shock fronts, overcompressive and compound shocks, etc. Numerical simulations show that CME shocks (generated in the lower corona) can have such a complex structure. The evolution of these CME shocks is followed during their propagation through the solar wind and, in particular, though the critical points in the wind. Complex IP events involving two CME shocks colliding to each other, as often observed, are also investigated. Finally, an analysis based on a parameter study of the impact of the resulting IP magnetic clouds on the Earth's bow shock involving 3D MHD simulations is presented and discussed. In addition, time accurate MHD simulations show how the magnetic reconnection at the Earth's bow shock is affected dramatically by the magnetic cloud impact. The CME shocks are important for `space weather' because they can easily be observed in radio wavelengths. This makes it possible to track the position of the CMEs/magnetic clouds and, hence, to follow their propagation through the corona. The topology of the shock at the Earth's magnetosphere at the impact of a magnetic cloud is important for the `geo-effectiveness' of the magnetic storms.

  11. MHD Advanced Power Train Phase I, Final Report, Volume 6

    SciTech Connect

    A. R. Jones

    1985-08-01

    Under contract to the Department of Energy, Westinghouse has prepared the definition of a program plan for the development of an MHD Advanced Power Train (APT). The scope of work of this contract includes conceptual designs of early commercial MHD/steam electric plants (topping/bottoming) ranging from 200 to 1000 Mw(e). These plant designs were prepared during 1982 and made use of a system analysis model that provides performance and design information and economic estimates. In early April 1984, DOE requested westinghouse to perform special studies under the existing APT contract to aid the Department in evaluating MHD program options. Two tasks were defined by DOE: the first task was to evaluate an 80 MW(t) integrated test system (with steam electric bottoming cycle) for installation at the CDIF in Butte, Montana; the second task was to investigate placing a 50 MW(e) MHD topping stage onto an existing steam electric plant (as a retrofit). This volume of the final report documents the results of these special studies. Highlights of the studies were presented orally to DOE on May 15, 1984.

  12. MHD simulations of DC helicity injection for current drive in tokamaks

    SciTech Connect

    Sovinec, C.R.; Prager, S.C.

    1994-12-01

    MHD computations of DC helicity injection in tokamak-like configurations show current drive with no ``loop voltage`` in a resistive, pressureless plasma. The self-consistently generated current profiles are unstable to resistive modes that partially relax the profile through the MHD dynamo mechanism. The current driven by the fluctuations leads to closed contours of average poloidal flux. However, the 1% fluctuation level is large enough to produce a region of stochastic magnetic field. A limited Lundquist number (S) scan from 2.5 {times} 10{sup 3} to 4 {times} 10{sup 4} indicates that both the fluctuation level and relaxation increase with S.

  13. MHD Technology Transfer, Integration and Review Committee. Second semiannual status report, July 1988--March 1989

    SciTech Connect

    Not Available

    1989-10-01

    As part of the MHD Integrated Topping Cycle (ITC) project, TRW was given the responsibility to organize, charter and co-chair, with the Department of Energy (DOE), an MHD Technology Transfer, Integration and Review Committee (TTIRC). The Charter of the TTIRC, which was approved by the DOE in June 1988 and distributed to the committee members, is included as part of this Summary. As stated in the Charter, the purpose of this committee is to: (1) review all Proof-of-Concept (POC) projects and schedules in the national MHD program; to assess their compatibility with each other and the first commercial MHD retrofit plant; (2) establish and implement technology transfer formats for users of this technology; (3) identify interfaces, issues, and funding structures directly impacting the success of the commercial retrofit; (4) investigate and identify the manner in which, and by whom, the above should be resolved; and (5) investigate and assess other participation (foreign and domestic) in the US MHD Program. The DOE fiscal year 1989 MHD Program Plan Schedule is included at the end of this Summary. The MHD Technology Transfer, Integration and Review Committee`s activities to date have focused primarily on the ``technology transfer`` aspects of its charter. It has provided a forum for the dissemination of technical and programmatic information among workers in the field of MHD and to the potential end users, the utilities, by holding semi-annual meetings. The committee publishes this semi-annual report, which presents in Sections 2 through 11 capsule summaries of technical progress for all DOE Proof-of-Concept MHD contracts and major test facilities.

  14. FLASH MHD simulations of experiments that study shock-generated magnetic fields

    NASA Astrophysics Data System (ADS)

    Tzeferacos, P.; Fatenejad, M.; Flocke, N.; Graziani, C.; Gregori, G.; Lamb, D. Q.; Lee, D.; Meinecke, J.; Scopatz, A.; Weide, K.

    2015-12-01

    We summarize recent additions and improvements to the high energy density physics capabilities in FLASH, highlighting new non-ideal magneto-hydrodynamic (MHD) capabilities. We then describe 3D Cartesian and 2D cylindrical FLASH MHD simulations that have helped to design and analyze experiments conducted at the Vulcan laser facility. In these experiments, a laser illuminates a carbon rod target placed in a gas-filled chamber. A magnetic field diagnostic (called a Bdot) employing three very small induction coils is used to measure all three components of the magnetic field at a chosen point in space. The simulations have revealed that many fascinating physical processes occur in the experiments. These include megagauss magnetic fields generated by the interaction of the laser with the target via the Biermann battery mechanism, which are advected outward by the vaporized target material but decrease in strength due to expansion and resistivity; magnetic fields generated by an outward expanding shock via the Biermann battery mechanism; and a breakout shock that overtakes the first wave, the contact discontinuity between the target material and the gas, and then the initial expanding shock. Finally, we discuss the validation and predictive science we have done for this experiment with FLASH.

  15. MHD activity in the ISX-B tokamak: experimental results and theoretical interpretation

    SciTech Connect

    Carreras, B.A.; Dunlap, J.L.; Bell, J.D.; Charlton, L.A.; Cooper, W.A.; Dory, R.A.; Hender, T.C.; Hicks, H.R.; Holmes, J.A.; Lynch, V.E.

    1982-01-01

    The observed spectrum of MHD fluctuations in the ISX-B tokamak is clearly dominated by the n=1 mode when the q=1 surface is in the plasma. This fact agrees well with theoretical predictions based on 3-D resistive MHD calculations. They show that the (m=1; n=1) mode is then the dominant instability. It drives other n=1 modes through toroidal coupling and n>1 modes through nonlinear couplings. These theoretically predicted mode structures have been compared in detail with the experimentally measured wave forms (using arrays of soft x-ray detectors). The agreement is excellent. More detailed comparisons between theory and experiment have required careful reconstructions of the ISX-B equilibria. The equilibria so constructed have permitted a precise evaluation of the ideal MHD stability properties of ISX-B. The present results indicate that the high ..beta.. ISX-B equilibria are marginally stable to finite eta ideal MHD modes. The resistive MHD calculations also show that at finite ..beta.. there are unstable resistive pressure driven modes.

  16. Antimicrobial susceptibility and antibiotic resistance gene transfer analysis of foodborne, clinical, and environmental Listeria spp. isolates including Listeria monocytogenes.

    PubMed

    Bertsch, David; Muelli, Mirjam; Weller, Monika; Uruty, Anaïs; Lacroix, Christophe; Meile, Leo

    2014-02-01

    The aims of this study were to assess antibiotic resistance pheno- and genotypes in foodborne, clinical, and environmental Listeria isolates, as well as to elucidate the horizontal gene transfer potential of detected resistance genes. A small fraction of in total 524 Listeria spp. isolates (3.1%) displayed acquired antibiotic resistance mainly to tetracycline (n = 11), but also to clindamycin (n = 4) and trimethoprim (n = 3), which was genotypically confirmed. In two cases, a tetracycline resistance phenotype was observed together with a trimethoprim resistance phenotype, namely in a clinical L. monocytogenes strain and in a foodborne L. innocua isolate. Depending on the applied guidelines, a differing number of isolates (n = 2 or n = 20) showed values for ampicillin that are on the edge between intermediate susceptibility and resistance. Transferability of the antibiotic resistance genes from the Listeria donors, elucidated in vitro by filter matings, was demonstrated for genes located on transposons of the Tn916 family and for an unknown clindamycin resistance determinant. Transfer rates of up to 10(-5) transconjugants per donor were obtained with a L. monocytogenes recipient and up to 10(-7) with an Enterococcus faecalis recipient, respectively. Although the prevalence of acquired antibiotic resistance in Listeria isolates from this study was rather low, the transferability of these resistances enables further spread in the future. This endorses the importance of surveillance of L. monocytogenes and other Listeria spp. in terms of antibiotic susceptibility. © 2014 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

  17. Recognition of a Nocardia transvalensis complex by resistance to aminoglycosides, including amikacin, and PCR-restriction fragment length polymorphism analysis.

    PubMed

    Wilson, R W; Steingrube, V A; Brown, B A; Blacklock, Z; Jost, K C; McNabb, A; Colby, W D; Biehle, J R; Gibson, J L; Wallace, R J

    1997-09-01

    Amikacin resistance, rare among nocardiae, was observed in 58 clinical isolates of nocardiae. All of these isolates hydrolyzed hypoxanthine, and 75 to 100% utilized citrate, D-galactose, and D-trehalose as sole carbon sources. Based on utilization of I-erythritol, D-glucitol, i-myo-inositol, D-mannitol, and ribitol and susceptibility to amoxicillin-clavulanic acid, the 58 isolates were separable into four groups. One group was negative for I-erythritol and ribitol and included all the isolates belonging to Nocardia asteroides complex antibiogram type IV. The remaining three groups were positive for I-erythritol and ribitol and were grouped within Nocardia transvalensis. The group that included the type strain was designated N. transvalensis sensu stricto, and the other two groups were designated new taxons 1 and 2. PCR-restriction fragment length polymorphism (RFLP) analysis of a 439-bp segment of the 65-kDa heat shock protein gene with XhoI and HinfI produced identical patterns for 53 (91%) and 58 (100%) isolates, respectively, and differentiated them from all other Nocardia taxa. NarI- and HaeIII-derived RFLP patterns clearly differentiated each of the four biochemically defined taxa. These four groups were also distinguishable by using the chromogenic substrates in Dade MicroScan test panels. By high-performance liquid chromatography, these isolates exhibited the same unique mycolic acid-ester elution patterns that differed from those of all other clinically significant nocardiae. Gas-liquid chromatographic analysis of fatty acids also produced similar patterns for all isolates that distinguished them from all other Nocardia taxa, but did not differentiate the four taxa within the complex. We propose the designation N. transvalensis complex for these four groups of nocardiae, pending further genetic evaluation.

  18. Ceramic component for MHD electrode

    DOEpatents

    Marchant, David D.; Bates, Junior L.

    1981-01-01

    A ceramic component which exhibits electrical conductivity down to near room temperatures has the formula: Hf.sub.x In.sub.y A.sub.z O.sub.2 where x=0.1 to 0.4, y=0.3 to 0.6, z=0.1 to 0.4 and A is a lanthanide rare earth or yttrium. The component is suitable for use in the fabrication of MHD electrodes or as the current leadout portion of a composite electrode with other ceramic components.

  19. Ceramic components for MHD electrode

    DOEpatents

    Marchant, D.D.

    A ceramic component which exhibits electrical conductivity down to near room temperatures has the formula: Hf/sub x/In/sub y/A/sub z/O/sub 2/ where x = 0.1 to 0.4, y = 0.3 to 0.6, z = 0.1 to 0.4 and A is a lanthanide rare earth or yttrium. The component is suitable for use in the fabrication of MHD electrodes or as the current leadout portion of a composite electrode with other ceramic components.

  20. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-07-01

    This eighteenth quarterly technical progress report of the MHD Integrated Topping cycle Project presents the accomplishments during the period November 1, 1991 to January 31, 1992. The precombustor is fully assembled. Manufacturing of all slagging stage components has been completed. All cooling panels were welded in place and the panel/shell gap was filled with RTV. Final combustor assembly is in progress. The low pressure cooling subsystem (LPCS) was delivered to the CDIF. Second stage brazing issues were resolved. The construction of the two anode power cabinets was completed.

  1. Global MHD model of the earth's magnetosphere

    NASA Technical Reports Server (NTRS)

    Wu, C. C.

    1983-01-01

    A global MHD model of the earth's magnetosphere is defined. An introduction to numerical methods for solving the MHD equations is given with emphasis on the shock-capturing technique. Finally, results concerning the shape of the magnetosphere and the plasma flows inside the magnetosphere are presented.

  2. Compendium of MHD-related terminology

    NASA Astrophysics Data System (ADS)

    Hart, A. T.; Lofftus, D. A.; Rudberg, D. A.; Green, R. A.

    The magnetohydrodynamic (MHD) researchers in the United States have joined together in the past few years to prove the viability of the technology. As new designs for hardware methods of operation, approaches for data analysis, and levels of understanding have been attained, a set of MHD-unique terminology has been developed but not always documented. A glossary of terminology unique to the study of MHD was compiled for SEAM 27 to provide an information source for workers in this field and to assist those interested in the commercial potential of MHD in reading and understanding technical articles on the subject. The terminology defined was primarily related to the U.S. proof-of-concept program of MHD development and eventual retrofitting of a coal fired plant with MHD equipment. Basic theoretical terms as well as terminology related to the commercialization of MHD were presented. Emphasis was placed on terms related to commercialization and those related to currently active areas of study. This paper builds on the SEAM 27 contribution. Areas of concentration in this paper are retrofit/power plant terminology, advanced measurement technology applicable to MHD, research sites.

  3. Workshop on Feedback Stabilization of MHD Stabilities

    SciTech Connect

    McGuire, K.; Kugel, H.; La Haye, R.; Mauel, M.; Nevins, W.; Prager, S.

    1996-12-31

    The feedback stabilization of MHD instabilities is an area of research that is critical for improving the performance and economic attractiveness of magnetic confinement devices. A Workshop dedicated to feedback stabilization of MHD instabilities was held from December 11-13, 1996 at the Princeton Plasma Physics Laboratory, Princeton NJ, USA. The resulting presentations, conclusions, and recommendations are summarized.

  4. Observational Tests of Recent MHD Turbulence Perspectives

    NASA Astrophysics Data System (ADS)

    Ghosh, Sanjoy

    2001-06-01

    This grant seeks to analyze the Heliospheric Missions data to test current theories on the angular dependence (with respect to mean magnetic field direction) of magnetohydrodynamic (MHD) turbulence in the solar wind. Solar wind turbulence may be composed of two or more dynamically independent components. Such components include magnetic pressure-balanced structures, velocity shears, quasi-2D turbulence, and slab (Alfven) waves. We use a method, developed during the first two years of this grant, for extracting the individual reduced spectra of up to three separate turbulence components from a single spacecraft time series. The method has been used on ISEE-3 data, Pioneer Venus Orbiter, Ulysses, and Voyager data samples. The correlation of fluctuations as a function of angle between flow direction and magnetic-field direction is the focus of study during the third year.

  5. Observational Tests of Recent MHD Turbulence Perspectives

    NASA Technical Reports Server (NTRS)

    Ghosh, Sanjoy; Guhathakurta, M. (Technical Monitor)

    2001-01-01

    This grant seeks to analyze the Heliospheric Missions data to test current theories on the angular dependence (with respect to mean magnetic field direction) of magnetohydrodynamic (MHD) turbulence in the solar wind. Solar wind turbulence may be composed of two or more dynamically independent components. Such components include magnetic pressure-balanced structures, velocity shears, quasi-2D turbulence, and slab (Alfven) waves. We use a method, developed during the first two years of this grant, for extracting the individual reduced spectra of up to three separate turbulence components from a single spacecraft time series. The method has been used on ISEE-3 data, Pioneer Venus Orbiter, Ulysses, and Voyager data samples. The correlation of fluctuations as a function of angle between flow direction and magnetic-field direction is the focus of study during the third year.

  6. Performance and flow characteristics of MHD seawater thruster

    SciTech Connect

    Doss, E.D.

    1990-01-01

    The main goal of the research is to investigate the effects of strong magnetic fields on the electrical and flow fields inside MHD thrusters. The results of this study is important in the assessment of the feasibility of MHD seawater propulsion for the Navy. To accomplish this goal a three-dimensional fluid flow computer model has been developed and applied to study the concept of MHD seawater propulsion. The effects of strong magnetic fields on the current and electric fields inside the MHD thruster and their interaction with the flow fields, particularly those in the boundary layers, have been investigated. The results of the three-dimensional computations indicate that the velocity profiles are flatter over the sidewalls of the thruster walls in comparison to the velocity profiles over the electrode walls. These nonuniformities in the flow fields give rise to nonuniform distribution of the skin friction along the walls of the thrusters, where higher values are predicted over the sidewalls relative to those over the electrode walls. Also, a parametric study has been performed using the three-dimensional MHD flow model to analyze the performance of continuous electrode seawater thrusters under different operating parameters. The effects of these parameters on the fluid flow characteristics, and on the thruster efficiency have been investigated. Those parameters include the magnetic field (10--20 T), thruster diameter, surface roughness, flow velocity, and the electric load factor. The results show also that the thruster performance improves with the strength of the magnetic field and thruster diameter, and the efficiency decreases with the flow velocity and surface roughness.

  7. An MHD model of the earth's magnetosphere

    NASA Technical Reports Server (NTRS)

    Wu, C. C.

    1985-01-01

    It is pointed out that the earth's magnetosphere arises from the interaction of the solar wind with the earth's geomagnetic field. A global magnetohydrodynamics (MHD) model of the earth's magnetosphere has drawn much attention in recent years. In this model, MHD equations are used to describe the solar wind interaction with the magnetosphere. In the present paper, some numerical aspects of the model are considered. Attention is given to the ideal MHD equations, an equation of state for the plasma, the model as an initial- and boundary-value problem, the shock capturing technique, computational requirements and techniques for global MHD modeling, a three-dimensional mesh system employed in the global MHD model, and some computational results.

  8. Magnetotail dynamics: MHD simulations of driven and spontaneous dynamic changes

    SciTech Connect

    Birn, J.; Schindler, K.; Hesse, M.

    1994-05-01

    The dynamic evolution of the magnetotail during growth phase and expansion phase of a substorm is studied through threedimensional time-dependent MHD simulations. To model growth phase effects, an external electric field with an equatorward inflow is applied at the boundaries over a finite time period. This leads to the formation of a thin current sheet with greatly enhanced current density in the near tail, embedded in the wider plasma/current sheet, which becomes diminished in strength. A faster, spontaneous current sheet formation occurs when entropy conservation is released in an isobaric model, while the ideal MHD constraint persists. This may be a suitable model for the late, explosive part of the growth phase. The transition to the substorm expansive phase is modeled by an increase in anomalous resistivity, using either uniform resistivity or a current density dependent resistivity which is turned on when the current density exceeds a certain threshold. In both cases the violation of ideal MHD leads to resistive instability and the formation of a near-Earth neutral line, fast flow, and plasmoid ejection, together with the dipolarization and current reduction in the region further earthward. The spontaneous increase in total region 1 type field-aligned currents associated with the disruptions of the thin current sheets is less significant than that found in earlier simulations of the disruption of a wider current sheet, whereas the driven increase in the region 1 type current is substantial. The results demonstrate that the same dynamic process which appears spontaneous in the behavior of some quantities might be interpreted as entirely driven from the observation of others.

  9. EVIDENCE OF ACTIVE MHD INSTABILITY IN EULAG-MHD SIMULATIONS OF SOLAR CONVECTION

    SciTech Connect

    Lawson, Nicolas; Strugarek, Antoine; Charbonneau, Paul E-mail: strugarek@astro.umontreal.ca

    2015-11-10

    We investigate the possible development of magnetohydrodynamical instabilities in the EULAG-MHD “millennium simulation” of Passos and Charbonneau. This simulation sustains a large-scale magnetic cycle characterized by solar-like polarity reversals taking place on a regular multidecadal cadence, and in which zonally oriented bands of strong magnetic fields accumulate below the convective layers, in response to turbulent pumping from above in successive magnetic half-cycles. Key aspects of this simulation include low numerical dissipation and a strongly sub-adiabatic fluid layer underlying the convectively unstable layers corresponding to the modeled solar convection zone. These properties are conducive to the growth and development of two-dimensional instabilities that are otherwise suppressed by stronger dissipation. We find evidence for the action of a non-axisymmetric magnetoshear instability operating in the upper portions of the stably stratified fluid layers. We also investigate the possibility that the Tayler instability may be contributing to the destabilization of the large-scale axisymmetric magnetic component at high latitudes. On the basis of our analyses, we propose a global dynamo scenario whereby the magnetic cycle is driven primarily by turbulent dynamo action in the convecting layers, but MHD instabilities accelerate the dissipation of the magnetic field pumped down into the overshoot and stable layers, thus perhaps significantly influencing the magnetic cycle period. Support for this scenario is found in the distinct global dynamo behaviors observed in an otherwise identical EULAG-MHD simulations, using a different degree of sub-adiabaticity in the stable fluid layers underlying the convection zone.

  10. Stability of the Halley Cometo-Sheath with Resistivity and Plasma Motion

    NASA Technical Reports Server (NTRS)

    Srivastava, K.

    1993-01-01

    The MHD stability of the cometary inner shealth determined by the balance between the inward Lorentz body force and the outward ion-neutral drag force is investigated by numerically solving the wave equations which include resistivity, plasma motion and plasma pressure with the help of two-point boundary value method.

  11. A study of remitted and treatment-resistant depression using MMPI and including pessimism and optimism scales.

    PubMed

    Suzuki, Masatoshi; Takahashi, Michio; Muneoka, Katsumasa; Sato, Koichi; Hashimoto, Kenji; Shirayama, Yukihiko

    2014-01-01

    The psychological aspects of treatment-resistant and remitted depression are not well documented. We administered the Minnesota Multiphasic Personality Inventory (MMPI) to patients with treatment-resistant depression (n = 34), remitted depression (n = 25), acute depression (n = 21), and healthy controls (n = 64). Pessimism and optimism were also evaluated by MMPI. ANOVA and post-hoc tests demonstrated that patients with treatment-resistant and acute depression showed similarly high scores for frequent scale (F), hypochondriasis, depression, conversion hysteria, psychopathic device, paranoia, psychasthenia and schizophrenia on the MMPI compared with normal controls. Patients with treatment-resistant depression, but not acute depression registered high on the scale for cannot say answer. Using Student's t-test, patients with remitted depression registered higher on depression and social introversion scales, compared with normal controls. For pessimism and optimism, patients with treatment-resistant depression demonstrated similar changes to acutely depressed patients. Remitted depression patients showed lower optimism than normal controls by Student's t-test, even though these patients were deemed recovered from depression using HAM-D. The patients with remitted depression and treatment-resistant depression showed subtle alterations on the MMPI, which may explain the hidden psychological features in these cohorts.

  12. A Study of Remitted and Treatment-Resistant Depression Using MMPI and Including Pessimism and Optimism Scales

    PubMed Central

    Suzuki, Masatoshi; Takahashi, Michio; Muneoka, Katsumasa; Sato, Koichi; Hashimoto, Kenji; Shirayama, Yukihiko

    2014-01-01

    Background The psychological aspects of treatment-resistant and remitted depression are not well documented. Methods We administered the Minnesota Multiphasic Personality Inventory (MMPI) to patients with treatment-resistant depression (n = 34), remitted depression (n = 25), acute depression (n = 21), and healthy controls (n = 64). Pessimism and optimism were also evaluated by MMPI. Results ANOVA and post-hoc tests demonstrated that patients with treatment-resistant and acute depression showed similarly high scores for frequent scale (F), hypochondriasis, depression, conversion hysteria, psychopathic device, paranoia, psychasthenia and schizophrenia on the MMPI compared with normal controls. Patients with treatment-resistant depression, but not acute depression registered high on the scale for cannot say answer. Using Student's t-test, patients with remitted depression registered higher on depression and social introversion scales, compared with normal controls. For pessimism and optimism, patients with treatment-resistant depression demonstrated similar changes to acutely depressed patients. Remitted depression patients showed lower optimism than normal controls by Student's t-test, even though these patients were deemed recovered from depression using HAM-D. Conclusions The patients with remitted depression and treatment-resistant depression showed subtle alterations on the MMPI, which may explain the hidden psychological features in these cohorts. PMID:25279466

  13. Off-design performance analysis of MHD generator channels

    NASA Astrophysics Data System (ADS)

    Wilson, D. R.; Williams, T. S.

    1980-01-01

    A computer code for performing parametric design point calculations, and evaluating the off-design performance of MHD generators has been developed. The program is capable of analyzing Faraday, Hall, and DCW channels, including the effect of electrical shorting in the gas boundary layers and coal slag layers. Direct integration of the electrode voltage drops is included. The program can be run in either the design or off-design mode. Details of the computer code, together with results of a study of the design and off-design performance of the proposed ETF MHD generator are presented. Design point variations of pre-heat and stoichiometry were analyzed. The off-design study included variations in mass flow rate and oxygen enrichment.

  14. Feasibility of MHD submarine propulsion

    SciTech Connect

    Doss, E.D. ); Sikes, W.C. )

    1992-09-01

    This report describes the work performed during Phase 1 and Phase 2 of the collaborative research program established between Argonne National Laboratory (ANL) and Newport News Shipbuilding and Dry Dock Company (NNS). Phase I of the program focused on the development of computer models for Magnetohydrodynamic (MHD) propulsion. Phase 2 focused on the experimental validation of the thruster performance models and the identification, through testing, of any phenomena which may impact the attractiveness of this propulsion system for shipboard applications. The report discusses in detail the work performed in Phase 2 of the program. In Phase 2, a two Tesla test facility was designed, built, and operated. The facility test loop, its components, and their design are presented. The test matrix and its rationale are discussed. Representative experimental results of the test program are presented, and are compared to computer model predictions. In general, the results of the tests and their comparison with the predictions indicate that thephenomena affecting the performance of MHD seawater thrusters are well understood and can be accurately predicted with the developed thruster computer models.

  15. MHD Simulations: Corotating Interaction Regions

    NASA Astrophysics Data System (ADS)

    Wiengarten, T.; Kleimann, J.; Fichtner, H.; Kissmann, R.

    2014-09-01

    Corotating Interaction Regions (CIRs) form in the solar wind when parcels of fast-speed wind interact with slow-speed wind due to the rotation of the Sun. The resulting buildup of pressure generates disturbances that, with increasing time (or distance from the Sun), may develop into a so-called forward-reverse shock pair. During solar-quiet times CIRs can be the dominant force shaping large-scale structures in the heliosphere. Studying CIRs is therefore important because the associated shocks are capable of e.g. accelerating energetic particles or deflecting cosmic rays. The global structure of CIRs can be modeled with an MHD approach that gives the plasma quantities needed to model the transport of particles in the heliosphere with e.g. stochastic differential equations. Here, we show results from 3D-MHD simulations with our code CRONOS for a) analytic boundary conditions where results can be compared to those obtained with a different code and b) boundary conditions derived with the Wang-Sheeley-Arge model from observational data (WSO), which are compared to spacecraft observations.

  16. MHD (Magnetohydrodynamics) recovery and regeneration

    SciTech Connect

    McIlroy, R. A.; Probert, P. B.; Lahoda, E. J.; Swift, W. M.; Jackson, D. M.; Prasad, J.; Martin, J.; Rogers, C.; Ho, K. K.; Senary, M. K.; Lee, S.; Westinghouse Electric Corp., Pittsburgh, PA; Argonne National Lab., IL; Tennessee Univ., Tullahoma, TN . Space Inst.; Hudson Engineering; Babcock and Wilcox Co., Alliance, OH . Re

    1988-10-01

    A two-phase program investigating MHD seed regeneration is described. In Phase I, bench scale experiments were carried out to demonstrate the technical feasibility of a proposed Seed Regeneration Process. The Phase I data has been used for the preliminary design of a Proof-of-Concept (POC) plant which will be built and tested in Phase II. The Phase I data will also be used to estimate the costs of a 300 Mw(t) demonstration plant for comparison with other processes. The Seed Regeneration Process consists of two major subprocesses; a Westinghouse Dry Reduction process and a modified Tampella (sulfur) Recovery process. The Westinghouse process reduces the recovered spent seed (i.e., potassium sulfate) to potassium polysulfide in a rotary kiln. The reduction product is dissolved in water to form green liquor, clarified to remove residual coal ash, and sent to the Tampella sulfur release system. The sulfur is released using carbon dioxide from flue gas in a two stage reaction. The sulfur is converted to elemental sulfur as a marketable by product. The potassium is crystallized from the green liquor and dried to the anhydrous form for return to the MHD unit.

  17. MHD air heater development technology. Technical progress report, July 1-September 30, 1980

    SciTech Connect

    1980-11-01

    The technology development of the directly-fired high temperature air heater (HTAH) for MHD power plants is described. Progress is reported on the three tasks. The first task is materials selection, evaluation, and development. The objective of this task is to continue development of ceramic materials technology for the directly-fired HTAH. Task two is operability, performance, and materials testing. The objectives of this task are to demonstrate the technical feasibility of operating a directly-fired HTAH (including both the heater matrix and valves), to continue obtaining information on life and corrosion resistance of HTAH materials, and to obtain design information for full-scale studies and future design work. The objectives of the full-scale design task are to begin the identification of HTAH control requirements and control system needs, and to continue full-scale study efforts incorporating updated materials and design information in order to identify development needs for the HTAH development program. (WHK)

  18. MHD air heater technology development. Annual technical progress report, January 1, 1980-December 31, 1980

    SciTech Connect

    1981-03-01

    Progress on the technology development of the directly-fired high temperature air heater (HTAH) for MHD power plants is described in detail. The objective of task 1 is to continue development of ceramic materials technology for the directly-fired HTAH. The objectives of task 2 are to demonstrate the technical feasibility of operating a directly-fired HTAH (including both the heater matrix and valves), to continue obtaining information on life and corrosion resistance of HTAH materials, and to obtain design information for full-scale studies and future design work. The objectives of task 3 are to begin the identification of HTAH control requirements and control system needs, and to continue full-scale study efforts incorporating updated materials and design information in order to identify development needs for the HTAH development program. (WHK)

  19. Toward 3D MHD modeling of neoclassical tearing mode suppression by ECCD

    NASA Astrophysics Data System (ADS)

    Pratt, J.; Westerhof, E.

    2012-09-01

    We propose a framework to extend the magnetohydrodynamic (MHD) equations to include electron cyclotron current drive (ECCD) and discuss previous models proposed by Giruzzi et al. [2] and by Hegna and Callen [3]. To model neoclassical tearing mode (NTM) instabilities and study the growth of magnetic islands as NTMs evolve, we employ the nonlinear reduced-MHD simulation JOREK. We present tearing-mode growth-rate calculations from JOREK simulations.

  20. A Review of the Possible Role of Constraints in MHD Turbulence

    NASA Astrophysics Data System (ADS)

    Pouquet, Annick

    2015-12-01

    The following sections are included: * Introduction * The context * The Kolmogorov law * The equations * What can we learn from statistical mechanics * Energy spectra * Weak MHD turbulence * When the weak regime breaks down * Intermittency * Exact laws * Explicit examples of non-universal behavior in MHD * The role of alignment between the velocity and the magnetic field * Can the dynamics of magnetic helicity play a role for energy scaling? * Can models help? * Conclusions * Acknowledgments * References

  1. Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant. Design Requirements Document (DRD)

    NASA Technical Reports Server (NTRS)

    Rigo, H. S.; Bercaw, R. W.; Burkhart, J. A.; Mroz, T. S.; Bents, D. J.; Hatch, A. M.

    1981-01-01

    A description and the design requirements for the 200 MWe (nominal) net output MHD Engineering Test Facility (ETF) Conceptual Design, are presented. Performance requirements for the plant are identified and process conditions are indicated at interface stations between the major systems comprising the plant. Also included are the description, functions, interfaces and requirements for each of these major systems. The lastest information (1980-1981) from the MHD technology program are integrated with elements of a conventional steam electric power generating plant.

  2. Novel Plasmid-Borne Multidrug Resistance Gene Cluster Including lsa(E) from a Linezolid-Resistant Enterococcus faecium Isolate of Swine Origin

    PubMed Central

    Si, Hongbin; Zhang, Wan-Jiang; Chu, Shengbo; Wang, Xiu-Mei; Dai, Lei; Hua, Xin; Dong, Zhimin

    2015-01-01

    A novel nonconjugative plasmid of 28,489 bp from a porcine linezolid-resistant Enterococcus faecium isolate was completely sequenced. This plasmid harbored a novel type of multiresistance gene cluster that comprised the resistance genes lnu(B), lsa(E), spw, aadE, aphA3, and two copies of erm(B), which account for resistance to macrolides, lincosamides, streptogramins, pleuromutilins, streptomycin, spectinomycin, and kanamycin/neomycin. Structural comparisons suggested that this plasmid might have developed from other enterococcal plasmids by insertion element (IS)-mediated interplasmid recombination processes. PMID:26324271

  3. Signatures of resistance to Lepeophtheirus salmonis include a TH2-type response at the louse-salmon interface.

    PubMed

    Braden, Laura M; Koop, Ben F; Jones, Simon R M

    2015-01-01

    Disease outbreaks with the salmon louse Lepeophtheirus salmonis cause significant economic losses in mariculture operations worldwide. Variable innate immune responses at the louse-attachment site contribute to differences in susceptibility among species such that members of Salmo spp. are more susceptible to infection than those of some Oncorhynchus spp. Relatively little is known about the mechanisms that contribute to disease resistance or susceptibility to L. salmonis in salmon. Here, we utilize histochemistry and transcriptomics in a comparative infection model with susceptible (Atlantic, sockeye) and resistant (coho) salmon. At least three cell populations (MHIIβ+, IL1β+, TNFα+) were activated in coho salmon skin during L. salmonis infection. Locally elevated expression of several pro-inflammatory mediators (e.g. IL1β, IL8, TNFα, COX2, C/EBPβ), and tissue repair enzymes (MMP9, MMP13) were detected in susceptible and resistant species. However, responses specific to coho salmon (e.g. IL4, IL6, TGFβ) or responses shared among susceptible salmon (e.g. SAP, TRF, Cath in Atlantic and sockeye salmon) provide evidence for species-specific pathways contributing to resistance or susceptibility, respectively. Our results confirm the importance of an early pro-inflammatory TH1-type pathway as an initial host response during infection with Pacific sea lice, and demonstrate subsequent regulatory TH2-type processes as candidate defense mechanisms in the skin of resistant coho salmon. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  4. Travelers Can Import Colistin-Resistant Enterobacteriaceae, Including Those Possessing the Plasmid-Mediated mcr-1 Gene

    PubMed Central

    Bernasconi, Odette J.; Kuenzli, Esther; Pires, João; Tinguely, Regula; Carattoli, Alessandra; Hatz, Christoph

    2016-01-01

    Stool samples from 38 travelers returning from India were screened for extended-spectrum cephalosporin- and carbapenem-resistant Enterobacteriaceae implementing standard selective plates. Twenty-six (76.3%) people were colonized with CTX-M or DHA producers, but none of the strains was colistin resistant and/or mcr-1 positive. Nevertheless, using overnight enrichment and CHROMagar Orientation plates supplemented with colistin, four people (10.5%) were found to be colonized with colistin-resistant Escherichia coli. One cephalosporin-susceptible sequence type 10 (ST10) strain carried a 4,211-bp ISApl1-mcr-1-ISApl1 element in an IncHI2 plasmid backbone. PMID:27297483

  5. Travelers Can Import Colistin-Resistant Enterobacteriaceae, Including Those Possessing the Plasmid-Mediated mcr-1 Gene.

    PubMed

    Bernasconi, Odette J; Kuenzli, Esther; Pires, João; Tinguely, Regula; Carattoli, Alessandra; Hatz, Christoph; Perreten, Vincent; Endimiani, Andrea

    2016-08-01

    Stool samples from 38 travelers returning from India were screened for extended-spectrum cephalosporin- and carbapenem-resistant Enterobacteriaceae implementing standard selective plates. Twenty-six (76.3%) people were colonized with CTX-M or DHA producers, but none of the strains was colistin resistant and/or mcr-1 positive. Nevertheless, using overnight enrichment and CHROMagar Orientation plates supplemented with colistin, four people (10.5%) were found to be colonized with colistin-resistant Escherichia coli One cephalosporin-susceptible sequence type 10 (ST10) strain carried a 4,211-bp ISApl1-mcr-1-ISApl1 element in an IncHI2 plasmid backbone. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  6. Seawater is a reservoir of multi-resistant Escherichia coli, including strains hosting plasmid-mediated quinolones resistance and extended-spectrum beta-lactamases genes.

    PubMed

    Alves, Marta S; Pereira, Anabela; Araújo, Susana M; Castro, Bruno B; Correia, António C M; Henriques, Isabel

    2014-01-01

    The aim of this study was to examine antibiotic resistance (AR) dissemination in coastal water, considering the contribution of different sources of fecal contamination. Samples were collected in Berlenga, an uninhabited island classified as Natural Reserve and visited by tourists for aquatic recreational activities. To achieve our aim, AR in Escherichia coli isolates from coastal water was compared to AR in isolates from two sources of fecal contamination: human-derived sewage and seagull feces. Isolation of E. coli was done on Chromocult agar. Based on genetic typing 414 strains were established. Distribution of E. coli phylogenetic groups was similar among isolates of all sources. Resistances to streptomycin, tetracycline, cephalothin, and amoxicillin were the most frequent. Higher rates of AR were found among seawater and feces isolates, except for last-line antibiotics used in human medicine. Multi-resistance rates in isolates from sewage and seagull feces (29 and 32%) were lower than in isolates from seawater (39%). Seawater AR profiles were similar to those from seagull feces and differed significantly from sewage AR profiles. Nucleotide sequences matching resistance genes bla TEM, sul1, sul2, tet(A), and tet(B), were present in isolates of all sources. Genes conferring resistance to 3rd generation cephalosporins were detected in seawater (bla CTX-M-1 and bla SHV-12) and seagull feces (bla CMY-2). Plasmid-mediated determinants of resistance to quinolones were found: qnrS1 in all sources and qnrB19 in seawater and seagull feces. Our results show that seawater is a relevant reservoir of AR and that seagulls are an efficient vehicle to spread human-associated bacteria and resistance genes. The E. coli resistome recaptured from Berlenga coastal water was mainly modulated by seagulls-derived fecal pollution. The repertoire of resistance genes covers antibiotics critically important for humans, a potential risk for human health.

  7. Seawater is a reservoir of multi-resistant Escherichia coli, including strains hosting plasmid-mediated quinolones resistance and extended-spectrum beta-lactamases genes

    PubMed Central

    Alves, Marta S.; Pereira, Anabela; Araújo, Susana M.; Castro, Bruno B.; Correia, António C. M.; Henriques, Isabel

    2014-01-01

    The aim of this study was to examine antibiotic resistance (AR) dissemination in coastal water, considering the contribution of different sources of fecal contamination. Samples were collected in Berlenga, an uninhabited island classified as Natural Reserve and visited by tourists for aquatic recreational activities. To achieve our aim, AR in Escherichia coli isolates from coastal water was compared to AR in isolates from two sources of fecal contamination: human-derived sewage and seagull feces. Isolation of E. coli was done on Chromocult agar. Based on genetic typing 414 strains were established. Distribution of E. coli phylogenetic groups was similar among isolates of all sources. Resistances to streptomycin, tetracycline, cephalothin, and amoxicillin were the most frequent. Higher rates of AR were found among seawater and feces isolates, except for last-line antibiotics used in human medicine. Multi-resistance rates in isolates from sewage and seagull feces (29 and 32%) were lower than in isolates from seawater (39%). Seawater AR profiles were similar to those from seagull feces and differed significantly from sewage AR profiles. Nucleotide sequences matching resistance genes blaTEM, sul1, sul2, tet(A), and tet(B), were present in isolates of all sources. Genes conferring resistance to 3rd generation cephalosporins were detected in seawater (blaCTX-M-1 and blaSHV-12) and seagull feces (blaCMY-2). Plasmid-mediated determinants of resistance to quinolones were found: qnrS1 in all sources and qnrB19 in seawater and seagull feces. Our results show that seawater is a relevant reservoir of AR and that seagulls are an efficient vehicle to spread human-associated bacteria and resistance genes. The E. coli resistome recaptured from Berlenga coastal water was mainly modulated by seagulls-derived fecal pollution. The repertoire of resistance genes covers antibiotics critically important for humans, a potential risk for human health. PMID:25191308

  8. Technical support for open-cycle MHD program. Progress report, January-June 1979

    SciTech Connect

    Bomkamp, D. H.

    1980-07-01

    The support program for open-cycle MHD at the Argonne National Laboratory consists of developing the analytical tools needed for investigation of the performance of the major components in the combined-cycle MHD/steam power system. The analytical effort is centered on the primary components of the system that are unique to MHD and, also, on the integration of these analytical models into a model of the entire power-producing system. The present project activities include modeling of the combustor, generator, seed deposition, and formation and decomposition of NO. Parametric studies were performed to evaluate the performance of the U-25B generator and to support the design of the US U-25B generator. Refinements and improvements to the MHD systems code and executive program are described.

  9. Technical support for open-cycle MHD program. Progress report, October-December 1979

    SciTech Connect

    Doss, E. D.

    1980-12-01

    The support program for open-cycle MHD at Argonne National Laboratory is developing the analytical tools needed to investigate the performance of the major components in the combined cycle MHD/steam power system. The analytical effort is centered on the primary components of the system that are unique to MHD and also on the integration of these analytical representations into a model of the entire power producing system. The present project activities include modeling of the combustor, MHD channel and diffuser, slag separator, radiant boiler and high-temperature air heater. In addition, these models are combined into a complete system model, which is, at present, capable of carrying out optimizations of the entire system relative to either thermodynamic efficiency or cost of electrical power. Progress is reported in detail.

  10. Corrosion and arc erosion in MHD channels

    NASA Astrophysics Data System (ADS)

    Rosa, R. J.; Pollina, R. J.

    1991-04-01

    The objective of this task is to study the corrosion and arc erosion of MHD materials in a cooperative effort with, and to support, the MHD topping cycle program. Materials tested in the Avco Research Laboratory/Textron facility, or materials which have significant MHD importance, will be analyzed to document their physical deterioration. Conclusions shall be drawn about their wear mechanisms and lifetime in the MHD environment with respect to the following issues; sulfur corrosion, electrochemical corrosion, and arc erosion. The impact of any materials or slag conditions on the level of power output and on the level of leakage current in the MHD channel will also be noted, where appropriate. Two phenomena that can effect the analysis of slag leakage current have been investigated and found significant. These are: (1) transverse current along the slag layer in the insulator walls of an MHD duct, and (2) electrode surface voltage drops. Both tend to reduce the value inferred for average plasma conductivity and increase the value inferred for axial leakage current. These two effects in combination are potentially capable of explaining the high leakage inferred. Corrosion on the water side of metal MHD duct wall elements has been examined in CDIF and Mark 7 generators. It appears to be controllable by adjusting the pH of the water and/or by controlling the dissolved oxygen content.

  11. MHD dynamo for the Reversed Field Pinch

    NASA Astrophysics Data System (ADS)

    Bonfiglio, Daniele; Cappello, Susanna; Escande, Dominique Frank; Spizzo, Gianluca

    2006-10-01

    MHD modelling is believed to provide a good description of large scale dynamics of the Reversed Field Pinch. In particular, 3-dimensional nonlinear simulations in a simple visco-resistive approximation [see Cappello PPCF 2004 and references therein] display many features in reasonable agreement with experiments. In recent times it has been shown that the general and basic tendency of the RFP to develop a more or less regular global kink type deformation of the plasma column forces a corresponding charge separation (consistent with quasi-neutrality) and a related electrostatic field. The ensuing electrostatic drift velocity (nearly) coincides with the dynamo velocity field traditionally considered to sustain the configuration [Bonfiglio,Cappello,Escande PRL 2005; Cappello,Bonfiglio,Escande PHP 2006]. In this presentation we review our present understanding in this subject. In particular we focus on the description of the formation of pure helical laminar RFP solutions, and study the relationship between the electrostatic structure and the topological properties of the magnetic field in the case of the less regular turbulent solutions, where the robustness of a chain of magnetic islands isolating the chaotic core from the edge has been recently highlighted [Spizzo,Cappello, Cravotta, Escande, Predebon, Marrelli, Martin, White, PRL 2006].

  12. Activation of MHD reconnection on ideal timescales

    NASA Astrophysics Data System (ADS)

    Landi, S.; Papini, E.; Del Zanna, L.; Tenerani, A.; Pucci, F.

    2017-01-01

    Magnetic reconnection in laboratory, space and astrophysical plasmas is often invoked to explain explosive energy release and particle acceleration. However, the timescales involved in classical models within the macroscopic MHD regime are far too slow to match the observations. Here we revisit the tearing instability by performing visco-resistive two-dimensional numerical simulations of the evolution of thin current sheets, for a variety of initial configurations and of values of the Lunquist number S, up to 107. Results confirm that when the critical aspect ratio of S 1/3 is reached in the reconnecting current sheets, the instability proceeds on ideal (Alfvénic) macroscopic timescales, as required to explain observations. Moreover, the same scaling is seen to apply also to the local, secondary reconnection events triggered during the nonlinear phase of the tearing instability, thus accelerating the cascading process to increasingly smaller spatial and temporal scales. The process appears to be robust, as the predicted scaling is measured both in inviscid simulations and when using a Prandtl number P  =  1 in the viscous regime.

  13. Flares and MHD Jets in Protostar

    NASA Astrophysics Data System (ADS)

    Hayashi, M.; Shibata, K.; Matsumoto, R.

    We present a magnetic reconnection model for hard X-ray emission and flare-like hard X-ray variabilities associated with protostars detected by ASCA. The energy released by protostellar flares is 102 - 105 times larger than solar flares. Moreover, the spectrum is harder. A new ingredient in protostellar flare is the existence of a protostellar disk which can twist the magnetic fields threading the protostellar disk. We carried out magnetohydrodynamic (MHD) simulations of the disk-star interaction. The closed magnetic loops connecting the central star and the disk are twisted by the rotation of the disk. In the presence of resistivity, magnetic reconnection takes place in the current sheet formed inside the expanding loops. Hot, outgoing plasmoid and post flare loops are formed as a result of the reconnection. Numerical results are consistent with the observed plasma temperature (107 - 108K), the length of the flaring loop (1011-1012cm), the total energy of X-ray flares (~1035-36erg). Furthermore, along the opening magnetic loops, hot jet is ejected in bipolar directions with speed 200-400 km/s. The speed and mass flow rate of the jet is consistent with those of optical jets. Our model can explain both the X-ray flare-like variability and mass outflow in star forming region.

  14. Development and Application of Predictive Tools for MHD Stability Limits in Tokamaks

    SciTech Connect

    Brennan, Dylan; Miller, G. P.

    2016-10-03

    This is a project to develop and apply analytic and computational tools to answer physics questions relevant to the onset of non-ideal magnetohydrodynamic (MHD) instabilities in toroidal magnetic confinement plasmas. The focused goal of the research is to develop predictive tools for these instabilities, including an inner layer solution algorithm, a resistive wall with control coils, and energetic particle effects. The production phase compares studies of instabilities in such systems using analytic techniques, PEST- III and NIMROD. Two important physics puzzles are targeted as guiding thrusts for the analyses. The first is to form an accurate description of the physics determining whether the resistive wall mode or a tearing mode will appear first as β is increased at low rotation and low error fields in DIII-D. The second is to understand the physical mechanism behind recent NIMROD results indicating strong damping and stabilization from energetic particle effects on linear resistive modes. The work seeks to develop a highly relevant predictive tool for ITER, advance the theoretical description of this physics in general, and analyze these instabilities in experiments such as ASDEX Upgrade, DIII-D, JET, JT-60U and NTSX. The awardee on this grant is the University of Tulsa. The research efforts are supervised principally by Dr. Brennan. Support is included for two graduate students, and a strong collaboration with Dr. John M. Finn of LANL. The work includes several ongoing collaborations with General Atomics, PPPL, and the NIMROD team, among others.

  15. Ex Vivo Activity of Endoperoxide Antimalarials, Including Artemisone and Arterolane, against Multidrug-Resistant Plasmodium falciparum Isolates from Cambodia

    DTIC Science & Technology

    2014-10-01

    of artemisinin combination therapies (ACTs) to treat artemisinin-resistant Plasmodium falciparum malaria . We conducted blinded ex vivo activity...Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates... malaria SYBR green I fluorescence (MSF) drug sensitivity tests in Plasmodium falciparum refer- ence clones and fresh ex vivo field isolates from

  16. Disk diffusion antimicrobial susceptibility testing of members of the family Legionellaceae including erythromycin-resistant variants of Legionella micdadei.

    PubMed Central

    Dowling, J N; McDevitt, D A; Pasculle, A W

    1984-01-01

    Disk diffusion antimicrobial susceptibility testing of members of the family Legionellaceae was accomplished on buffered charcoal yeast extract agar by allowing the bacteria to grow for 6 h before placement of the disks, followed by an additional 42-h incubation period before the inhibitory zones were measured. This system was standardized by comparing the zone sizes with the MICs for 20 antimicrobial agents of nine bacterial strains in five Legionella species and of 19 laboratory-derived, erythromycin-resistant variants of Legionella micdadei. A high, linear correlation between zone size and MIC was found for erythromycin, trimethoprim, penicillin, ampicillin, carbenicillin, cephalothin, cefamandole, cefoxitin, moxalactam, chloramphenicol, vancomycin, and clindamycin. Disk susceptibility testing could be employed to screen Legionella isolates for resistance to any of these antimicrobial agents, of which only erythromycin is known to be efficacious in the treatment of legionellosis. With selected antibiotics, disk susceptibility patterns also appeared to accurately identify to the species level the legionellae. The range of the MICs of the legionellae for rifampin and the aminoglycosides was too small to determine whether the correlation of zone size with MIC was linear. However, laboratory-derived, high-level rifampin-resistant variants of L. micdadei demonstrated no inhibition zone around the rifampin disk, indicating that disk susceptibility testing would likely identify a rifampin-resistant clinical isolate. Of the antimicrobial agents tested, the only agents for which disk susceptibility testing was definitely not possible on buffered charcoal yeast extract agar were oxacillin, the tetracyclines, and the sulfonamides. PMID:6565706

  17. A three dimensional MHD model of the earth's magnetosphere

    NASA Technical Reports Server (NTRS)

    Wu, C. C.; Walker, R. J.; Dawson, J. M.

    1981-01-01

    The results of a global MHD calculation of the steady state solar wind interaction with a dipole magnetic field are presented. The computer code used, being much faster than previous codes, makes it possible to increase the number of grid points in the system by an order of magnitude. The resulting model qualitatively reproduces many of the observed features of the quiet time magnetosphere including the bow shock, magnetopause, and plasma sheet.

  18. MHD generator with improved network coupling electrodes to a load

    DOEpatents

    Rosa, Richard J.

    1977-01-01

    An MHD generator has a plurality of segmented electrodes extending longitudinally of a duct, whereby progressively increasing high DC voltages are derived from a set of cathode electrodes and progressively increasing low DC voltages are derived from a set of anode electrodes. First and second load terminals are respectively connected to the cathode and anode electrodes by separate coupling networks, each of which includes a number of SCR's and a number of diode rectifiers.

  19. MHD channel development, part 2

    NASA Astrophysics Data System (ADS)

    1989-12-01

    This is the final report of work performed by Avco Research Laboratory, Inc. for the U.S. Department of Energy, Pittsburgh Energy Technology Center. The overall objectives of this program were: to contribute, by appropriate systematic experimental and analytical investigations, to the engineering data base necessary for the design and construction of MHD generators at the 50 MW(sub th) and ultimately at commercial sizes; and to design and fabricate specific hardware items to be tested at a site to be specified by DOE. The program consisted of a series of related tasks, which are described in subsequent sections of this report. Section 2.0 summarizes the important results of the entire program.

  20. Particle acceleration in MHD turbulence

    NASA Astrophysics Data System (ADS)

    Beresnyak, Andrey

    2017-05-01

    MHD Turbulence describes dynamics of astrophysical plasmas on large scale. It is characterized by energy transfer between different scales and the exchange of energy with nonthermal population - typically cosmic rays. Recent progress in theory regarding almost all basic regimes of turbulence - from the dynamo to the decaying case and the asymptotic scaling laws, allowed us to proceed with more observationally motivated questions. One of them is why almost all strongly magnetized environments are indeed observable, e.g. why such environments are infused with high-energy particles, their distributions stretching to energies orders of magnitude higher than thermal. It turns out that there are generic mechanisms of acceleration in turbulence, both second and first order in v/c, the latter was somehow unnoticed. These generic mechanisms may explain the ubiquity of non-thermal tails in various magnetized astrophysical environments, e.g. solar chromosphere, pulsar magnetospheres, jets from supermassive black holes, gamma-ray bursts, etc.

  1. MHD-EMP analysis and protection. Technical report. [MHD-EMP (magnetohydrodynamic-electromagnetic pulse)

    SciTech Connect

    Barnes, P.R.; Tesche, F.M.; McConnell, B.W.; Vance, E.F.

    1993-09-01

    A large nuclear detonation at altitudes of several hundred kilometers above the earth distorts the earth's magnetic field and produces a strong magnetohydrodynamic-electromagnetic pulse (MHD-EMP). MHD-EMP is similar to solar geomagnetic storms in its global and low frequency (less than 1 Hz) nature except that it can be more intense with a shorter duration. It will induce quasi-dc currents in long lines. The MHD-EMP induced currents may cause large voltage fluctuations and severe harmonic distortion in commercial electric power systems. Several MHD-EMP coupling models for predicting the induced current on a wide variety of conducting structures are described, various simulation concepts are summarized, and the results from several MHD-EMP tests are presented. To mitigate the effects of MHD-EMP on a facility, long conductors must be isolated from the building, and the commercial power harmonics and voltage swings must be addressed. It is found that facilities can be protected against MHD-EMP by using methods which are consistent with standard engineering practices. MHD-EMP Interaction Analysis, Power Line Model, MHD-EMP Protection Guidelines, Transformer Test.

  2. Thyroid profiles in a patient with resistance to thyroid hormone and episodes of thyrotoxicosis, including repeated painless thyroiditis.

    PubMed

    Taniyama, Matsuo; Otsuka, Fumiko; Tozaki, Teruaki; Ban, Yoshiyuki

    2013-07-01

    Thyrotoxic disease can be difficult to recognize in patients with resistance to thyroid hormone (RTH) because the clinical symptoms of thyrotoxicosis cannot be observed, and thyrotropin (TSH) may not be suppressed because of hormone resistance. Painless thyroiditis is a relatively common cause of thyrotoxicosis, but its occurrence in RTH has not been reported. We assessed the thyroid profile in a patient with RTH and episodes of thyrotoxicosis who experienced repeated painless thyroiditis. A 44-year-old Japanese woman with RTH, which was confirmed by the presence of a P453A mutation in the thyroid hormone receptor β (TRβ) gene, showed a slight elevation of the basal levels of thyroid hormones, which indicated that her pituitary RTH was mild. She experienced a slight exacerbation of hyperthyroxinemia concomitant with TSH suppression. A diagnosis of painless thyroiditis was made because of the absence of TSH receptor antibodies, low Tc-99m pertechnetate uptake by the thyroid gland, and transient suppression followed by a slight elevation of TSH following the elevation of thyroid hormones. The patient's complaints of general malaise and occasional palpitations did not change throughout the course of painless thyroiditis. Three years later, painless thyroiditis occurred again without any deterioration of the clinical manifestations. Mild pituitary RTH can be overcome by slight exacerbation of hyperthyroxinemia during mild thyrotoxicosis. When pituitary resistance is severe and TSH is not suppressed, thyrotoxicosis may be overlooked.

  3. 3D MHD disruptions simulations of tokamaks plasmas

    NASA Astrophysics Data System (ADS)

    Paccagnella, Roberto; Strauss, Hank; Breslau, Joshua

    2008-11-01

    Tokamaks Vertical Displacement Events (VDEs) and disruptions simulations in toroidal geometry by means of a single fluid visco-resistive magneto-hydro-dynamic (MHD) model are presented in this paper. The plasma model, implemented in the M3D code [1], is completed with the presence of a 2D homogeneous wall with finite resistivity. This allows the study of the relatively slowly growing magneto-hydro-dynamical perturbation, the resistive wall mode (RWM), which is, in this work, the main drive of the disruptions. Amplitudes and asymmetries of the halo currents pattern at the wall are also calculated and comparisons with tokamak experimental databases and predictions for ITER are given. [1] W. Park, E.V. Belova, G.Y. Fu, X.Z. Tang, H.R. Strauss, L.E. Sugiyama, Phys. Plasmas 6 (1999) 1796.

  4. Linear MHD Stability Analysis of the SSPX Spheromak

    NASA Astrophysics Data System (ADS)

    Jayakumar, R.; Cohen, B. I.; Hooper, E. B.; Lodestro, L. L.; McLean, H. S.; Pearlstein, L. D.; Wood, R.; Turnbull, A. D.; Sovinec, C.

    2007-11-01

    Good correlation between the toroidal mode numbers of measured magnetic fluctuations in high temperature SSPX plasmas and presence of low-order rational surfaces in the reconstructed q profiles, suggests that the quality of magnetic surfaces in SSPX is sufficiently good for applying standard linear MHD stability analyses. Previously we have reported on benchmarking the code NIMROD against GATO, with good agreement in growth rates for ideal-MHD internal kinks and an external kinks with no current on open field lines (for equilibria imported from the code Corsica). Recent stability analyses also show that presence of low order rational surfaces causes internal modes to become unstable. We will report on the progress in applying these tools for assessing beta limits in SSPX, using NIMROD analyses including current on open field lines and for comparison with experiments.

  5. Stabilization of global MHD instabilities by toroidal plasma rotation

    SciTech Connect

    Chu, M.S.; Miller, R.L.; Bondeson, A.; Luetjens, H.; DeRidder, G.; Sauter, O.

    1995-07-01

    Theoretical study and experimental observations suggest that rotation can play a crucial role in determining plasma stability. Since conventional magnetohydrodynamic (MHD) analysis ignores rotation, more advanced computational tools are being developed to confirm the theoretical understanding and to perform comparison between theory and experiment. In a previous work, the authors reported on the formulation and computation of MHD modes in plasmas with a small (subsonic) toroidal rotation. R.otation is found to have a substantial stabilizing effect under many circumstances. In this work, they extend the formulation in Ref. 4 to include an arbitrary (large) toroidal plasma rotation. It is the purpose of this work to examine the difference between these two formulations and report on results from computations using these formulations.

  6. A study of runaway electron confinement and theory of neoclassical MHD turbulence

    SciTech Connect

    Kwon, Oh Jin

    1989-07-01

    This thesis consists of two major studies: a study of runaway electron confinement and a theory of neoclassical MHD turbulence. The aim of the former is to study the structure of internal magnetic turbulence in tokamaks, which is thought by many to be responsible for the heat transport. The aim of the latter is to extend existing theories of MHD turbulence in tokamaks into experimentally relevant low-collisionality regimes. This section contains a theory of neoclassical pressure-gradient-driven turbulence and a theory of neoclassical resistivity-gradient-driven turbulence.

  7. Equilibrium and global MHD stability study of KSTAR high beta plasmas under passive and active mode control

    NASA Astrophysics Data System (ADS)

    Katsuro-Hopkins, O.; Sabbagh, S. A.; Bialek, J. M.; Park, H. K.; Bak, J. G.; Chung, J.; Hahn, S. H.; Kim, J. Y.; Kwon, M.; Lee, S. G.; Yoon, S. W.; You, K.-I.; Glasser, A. H.; Lao, L. L.

    2010-02-01

    The Korea Superconducting Tokamak Advanced Research, KSTAR, is designed to operate a steady-state, high beta plasma while retaining global magnetohydrodynamic (MHD) stability to establish the scientific and technological basis of an economically attractive fusion reactor. An equilibrium model is established for stability analysis of KSTAR. Reconstructions were performed for the experimental start-up scenario and experimental first plasma operation using the EFIT code. The VALEN code was used to determine the vacuum vessel current distribution. Theoretical high beta equilibria spanning the expected operational range are computed for various profiles including generic L-mode and DIII-D experimental H-mode pressure profiles. Ideal MHD stability calculations of toroidal mode number of unity using the DCON code shows a factor of 2 improvement in the wall-stabilized plasma beta limit at moderate to low plasma internal inductance. The planned stabilization system in KSTAR comprises passive stabilizing plates and actively cooled in-vessel control coils (IVCCs) designed for non-axisymmetric field error correction and stabilization of slow timescale MHD modes including resistive wall modes (RWMs). VALEN analysis using standard proportional gain shows that active stabilization near the ideal wall limit can be reached with feedback using the midplane segment of the IVCC. The RMS power required for control using both white noise and noise taken from NSTX active stabilization experiments is computed for beta near the ideal wall limit. Advanced state-space control algorithms yield a factor of 2 power reduction assuming white noise while remaining robust with respect to variations in plasma beta.

  8. Towards an MHD theory for the standoff distance of Earth's bow shock

    NASA Technical Reports Server (NTRS)

    Cairns, Iver H.; Grabbe, Crockett L.

    1994-01-01

    An MHD theory is developed for the stand-off distance a(sub s) of the bow shock and the thickness delta(sub ms) of the magnetosheath, using the empirical Spreiter et al. relation delta(sub ms) = kX and the MHD density ratio X across the shock. The theory includes as special cases the well-known gasdynamic theory and associated phenomenological MHD-like models for delta(sub ms) and a(sub s). In general, however, MHD effects produce major differences from previous models, especially at low Alfven (M(sub A)) and sonic (M(sub S)) Mach numbers. The magnetic field orientation, M(sub A), M(sub S) and the ratio of specific heats gamma are all important variables of the theory. Three principal conclusions are reached. First, the gasdynamic and phenomenological models miss important dependances on field orientation and M(sub S) and generally provide poor approximations to the MHD results. Second, changes in field orientation and M(sub S) are predicted to cause factor of approximately 4 changes in delta(sub ms) at low M(sub A). Third, using Spreiter et al.'s value for k in the MHD theory leads to maximum a(sub s) values at low M(sub A) and nominal M(sub S) that are much smaller than observations and MHD simulations require. Resolving this problem requires either the modified Spreiter-like relation and larger k found in recent MHD simulations and/or breakdown in the Spreiter-like relation at very low M(sub A).

  9. Towards an MHD theory for the standoff distance of Earth's bow shock

    NASA Technical Reports Server (NTRS)

    Cairns, Iver H.; Grabbe, Crockett L.

    1994-01-01

    An MHD theory is developed for the stand-off distance a(sub s) of the bow shock and the thickness delta(sub ms) of the magnetosheath, using the empirical Spreiter et al. relation delta(sub ms) = kX and the MHD density ratio X across the shock. The theory includes as special cases the well-known gasdynamic theory and associated phenomenological MHD-like models for delta(sub ms) and a(sub s). In general, however, MHD effects produce major differences from previous models, especially at low Alfven (M(sub A)) and sonic (M(sub S)) Mach numbers. The magnetic field orientation, M(sub A), M(sub S) and the ratio of specific heats gamma are all important variables of the theory. Three principal conclusions are reached. First, the gasdynamic and phenomenological models miss important dependances on field orientation and M(sub S) and generally provide poor approximations to the MHD results. Second, changes in field orientation and M(sub S) are predicted to cause factor of approximately 4 changes in delta(sub ms) at low M(sub A). Third, using Spreiter et al.'s value for k in the MHD theory leads to maximum a(sub s) values at low M(sub A) and nominal M(sub S) that are much smaller than observations and MHD simulations require. Resolving this problem requires either the modified Spreiter-like relation and larger k found in recent MHD simulations and/or breakdown in the Spreiter-like relation at very low M(sub A).

  10. Towards an MHD Theory for the Standoff Distance of Earth's Bow Shock

    NASA Technical Reports Server (NTRS)

    Carins, Iver H.; Grabbe, Crockett L.

    1994-01-01

    A magnetohydrodynamic (MHD) theory is developed for the standoff distance a(s) of the bow shock and the thickness Delta(ms) of the magnetosheath, using the empirical Spreiter et al. relation Delta(ms) = kX and the MHD density ratio X across the shock. The theory includes as special cases the well-known gasdynamic theory and associated phenomenological MHD-like models for Delta(ms) and As. In general, however, MHD effects produce major differences from previous models, especially at low Alfev (Ma) and Sonic (Ms) Mach numbers. The magnetic field orientation Ma, Ms and the ratio of specific heats gamma are all important variables of the theory. In contrast, the fast mode Mach number need play no direct role. Three principle conclusions are reached. First the gasdynamic and phenomenological models miss important dependences of field orientation and Ms generally provide poor approximations to the MHD results. Second, changes in field orientation and Ms are predicted to cause factor of approximately 4 changes in Delta(ms) at low Ma. These effects should be important when predicting the shock's location or calculating gramma from observations. Third, using Spreiter et al.'s value for k in the MHD theory leads to maxima a(s) values at low Ma and nominal Ms that are much smaller than observations and MHD simulations require. Resolving this problem requires either the modified Spreiter-like relation and larger k found in recent MHD simulations and/or a breakdown in the Spreiter-like relation at very low Ma.

  11. Validation of EFIT++ MHD Equilibrium Reconstructions on DIII-D

    NASA Astrophysics Data System (ADS)

    Cornille, B.; Lanctot, M. J.; Lao, L. L.; Appel, L. C.; Meneghini, O.; Holcomb, C. T.

    2013-10-01

    MHD force balance calculations play a key role in the optimization of transport and stability in tokamaks. In high confinement tokamak plasmas, reconstructions of the MHD plasma equilibrium are needed to resolve key profile features including the edge pressure pedestal and resulting bootstrap current. The EFIT code is the standard tool for calculating MHD force balance in DIII-D and many tokamaks. This code has recently been rebuilt to be machine-independent in order to facilitate cross-machine comparisons. This update, EFIT++, is in its late stages of development and requires validation for widespread use. Benchmarking of EFIT++ against the established EFIT cases including motional Stark effect measurements from DIII-D will be presented. Work supported by the the National Undergraduate Fellowship Program in Plasma Physics and Fusion Energy Sciences and the US Department of Energy under DE-FC02-04ER54698, DE-AC05-06OR23100 and DE-AC52-07NA27344.

  12. Solar driven liquid metal MHD power generator

    NASA Technical Reports Server (NTRS)

    Lee, J. H.; Hohl, F. (Inventor)

    1983-01-01

    A solar energy collector focuses solar energy onto a solar oven which is attached to a mixer which in turn is attached to the channel of a MHD generator. Gas enters the oven and a liquid metal enters the mixer. The gas/liquid metal mixture is heated by the collected solar energy and moves through the MHD generator thereby generating electrical power. The mixture is then separated and recycled.

  13. MHD Instabilities in Simple Plasma Configuration

    DTIC Science & Technology

    1984-01-01

    cause the field lines to break and reconnect. . This work is divided into two parts. Chapters " describe linear theory and Chapters -XV- describe the...details in any non- linear theory can rapidly mushroom out of all proportion. For this reason much work in nonlinear MHD theory is done by numerical...99 IX. INSTABILITIES IN A TOROIDAL PLASMA ........................ 125 X. QUASI- LINEAR THEORY OF MHD INSTABILITIES ........... 133

  14. Applying MHD Results to a Scramjet Vehicle

    DTIC Science & Technology

    2007-02-12

    1194, Reno, NV, January 2005. 10. Rosa, R.J., "Magnetohydrodynamic Energy Conversion", Hemisphere Publishing Corp., New York, 1968, Revised Printing ...Introduction and Background Projects Analytical and experimental studies of both electrohydrodynamic (EHD) and magnetohydrodynamic (MHD) application to...Institute, Tullahoma, TN, June 1981. 26. Vendell, E.W., "Free- Jet Electrical Conductivity Profiles of a Seeded MHD Combustion Plasma", 15"’ Symposium

  15. Solar driven liquid metal MHD power generator

    NASA Astrophysics Data System (ADS)

    Lee, J. H.; Hohl, F.

    1983-06-01

    A solar energy collector focuses solar energy onto a solar oven which is attached to a mixer which in turn is attached to the channel of a MHD generator. Gas enters the oven and a liquid metal enters the mixer. The gas/liquid metal mixture is heated by the collected solar energy and moves through the MHD generator thereby generating electrical power. The mixture is then separated and recycled.

  16. MHD heat and seed recovery technology project

    SciTech Connect

    Petrick, M.; Johnson, T. R.

    1980-08-01

    The MHD Heat and Seed Recovery Technology Project at Argonne National Laboratory is obtaining information for the design and operation of the steam plant downstream of the MHD channel-diffuser, and of the seed regeneration process. The project goal is to supply the engineering data required in the design of components for prototype and demonstration MHD facilities. The work is being done in close cooperation with the Heat Recovery-Seed Recovery facility, which will be a 20-MW pilot plant of the MHD steam bottoming system. The primary effort of the HSR Technology Project is directed toward experimental investigations of critical issues, such as 1) NO/sub x/ behavior in the radiant boiler and secondary combustor; 2) radiant boiler design to meet the multiple requirements of steam generation, NO/sub x/ decomposition, and seed slag separation; 3) effects of solid or liquid seed deposits on heat transfer and gas flow in the steam and air heaters; 4) formation, growth, and deposition of seed-slag particles, 5) character of the combustion gas effluents, and 6) the corrosion and erosion of ceramic and metallic materials of construction. These investigations are performed primarily in a 2-MW test facility, Argonne MHD Process Engineering Laboratory (AMPEL). Other project activities are related to studies of the thermochemistry of the seed-slag combustion gas system, identification of ceramic and metallic materials for service in the MHD-steam plant, and evaluation of seed regeneration processes. Progress is reported.

  17. MHD simulation of RF current drive in MST

    NASA Astrophysics Data System (ADS)

    Hendries, E. R.; Anderson, J. K.; Diem, S.; Forest, C. B.; Harvey, R. W.; Reusch, J. A.; Seltzman, A. H.; Sovinec, C. R.

    2014-02-01

    Auxiliary heating and current drive using RF waves such as the electron Bernstein wave (EBW) promises to advance the performance of the reversed field pinch (RFP). In previous computational work [1], a hypothetical edge-localized current drive is shown to suppress the tearing activity which governs the macroscopic transport properties of the RFP. The ideal conditions for tearing stabilization include a reduced toroidal induction, and precise width and radial position of the Gaussian-shaped external current drive. In support of the EBW experiment on the Madison Symmetric Torus, an integrated modeling scheme now incorporates ray tracing and Fokker-Plank predictions of auxiliary current into single fluid MHD. Simulations at low Lundquist number (S ˜ 104) generally agree with the previous work; significantly more burdensome simulations at MST-like Lundquist number (S ˜ 3×106) show unexpected results. The effect on nonlinearly saturated current profile by a particular RF-driven external force decreases in magnitude and widens considerably as the Lundquist number increases toward experimental values. Simulations reproduce the periodic current profile relaxation events observed in experiment (sawteeth) in the absence of current profile control. Reduction of the tearing mode amplitudes is still observable; however, reduction is limited to periods between the large bursts of magnetic activity at each sawtooth. The sawtoothing pattern persists with up to 10 MW of externally applied RF power. Periods with prolonged low tearing amplitude are predicted with a combination of external current drive and a reduced toroidal loop voltage, consistent with previous conclusions. Finally, the resistivity profile is observed to have a strong effect on the optimal externally driven current profile for mode stabilization.

  18. MHD simulation of RF current drive in MST

    SciTech Connect

    Hendries, E. R.; Anderson, J. K.; Forest, C. B.; Reusch, J. A.; Seltzman, A. H.; Sovinec, C. R.; Diem, S.; Harvey, R. W.

    2014-02-12

    Auxiliary heating and current drive using RF waves such as the electron Bernstein wave (EBW) promises to advance the performance of the reversed field pinch (RFP). In previous computational work [1], a hypothetical edge-localized current drive is shown to suppress the tearing activity which governs the macroscopic transport properties of the RFP. The ideal conditions for tearing stabilization include a reduced toroidal induction, and precise width and radial position of the Gaussian-shaped external current drive. In support of the EBW experiment on the Madison Symmetric Torus, an integrated modeling scheme now incorporates ray tracing and Fokker-Plank predictions of auxiliary current into single fluid MHD. Simulations at low Lundquist number (S ∼ 10{sup 4}) generally agree with the previous work; significantly more burdensome simulations at MST-like Lundquist number (S ∼ 3×10{sup 6}) show unexpected results. The effect on nonlinearly saturated current profile by a particular RF-driven external force decreases in magnitude and widens considerably as the Lundquist number increases toward experimental values. Simulations reproduce the periodic current profile relaxation events observed in experiment (sawteeth) in the absence of current profile control. Reduction of the tearing mode amplitudes is still observable; however, reduction is limited to periods between the large bursts of magnetic activity at each sawtooth. The sawtoothing pattern persists with up to 10 MW of externally applied RF power. Periods with prolonged low tearing amplitude are predicted with a combination of external current drive and a reduced toroidal loop voltage, consistent with previous conclusions. Finally, the resistivity profile is observed to have a strong effect on the optimal externally driven current profile for mode stabilization.

  19. [Genetic analysis of multidrug-resistant Streptococcus pneumoniae including meropenem resistance that was isolated from elderly residents with pneumonia in nursing-care facilities].

    PubMed

    Ota, Kazuko; Chiba, Naoko; Sato, Kentaro; Nara, Syoetu; Kato, Satoko; Kanazawa, Hisao; Ikejima, Shin; Takahashi, Yoshihiro; Iwata, Satoshi; Ubukata, Kimiko

    2014-07-01

    From February to December 20XX, penicillin-resistant Streptococcus pneumoniae (PRSP) showing MICs of 16-32 microg/mL to cefotaxime (CTX) and 4-8 microg/mL to meropenem (MEPM) were isolated from 6 patients hospitalized at the general hospital S (2 cases) and hospital A (4 cases), close to the hospital S. Five elderly patients among these six cases came from nursing care facilities or nursing care-related medical facilities. All elderly persons (mean age: 81.7 years) were diagnosed as having pneumonia at the time of admission and the problematic PRSP was isolated from sputum samples collected on admission. Notably, all of these PRSP isolates simultaneously showed high resistance to macrolide agents mediated by an erm (B) gene and to fluoroquinolone agents via mutations in the gyrA and parC genes. Eventually, they were identified as multidrug-resistant S. pneumoniae (MDRSP) with high resistance to many agents. The capsule type of all strains was serotype 19F and multilocus sequence typing (MLST) revealed that they belonged to clonal complex (CC) 7993, which has not been reported before. It was thus concluded that the MDRSP that had spread within the nursing facilities was transmitted to the general hospitals via the elderly inpatients with pneumonia caused by these agents. Although one case finally had a poor outcome, the pneumococcal infection was not the direct trigger of the event. The current ratio of MDRSP is concluded to be very low. However, general hospitals that accept patients for therapeutic purposes from nursing-care facilities have to share epidemiological information in a timely manner with the nursing homes to prevent nosocomial infections.

  20. Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents

    PubMed Central

    Wang, Richard C.; Chen, Xinmei; Parissenti, Amadeo M.; Joy, Anil A.; Tuszynski, Jack; Brindley, David N.

    2017-01-01

    Introduction One of the main reasons for disease recurrence in the curative breast cancer treatment setting is the development of drug resistance. Microtubule targeted agents (MTAs) are among the most commonly used drugs for the treatment of breaset cancer and therefore overcoming taxane resistance is of primary clinical importance. Our group has previously demonstrated that the microtubule dynamics of docetaxel-resistant MCF-7TXT cells are insensitivity to docetaxel due to the distinct expression profiles of β-tubulin isotypes in addition to the high expression of p-glycoprotein (ABCB1). In the present investigation we examined whether taxane-resistant breast cancer cells are more sensitive to microtubule destabilizing agents including vinca alkaloids and colchicine-site binding agents (CSBAs) than the non-resistant cells. Methods Two isogenic MCF-7 breast cancer cell lines were selected for resistance to docetaxel (MCF-7TXT) and the wild type parental cell line (MCF-7CC) to examine if taxane-resistant breast cancer cells are sensitive to microtubule-destabilizing agents including vinca alkaloids and CSBAs. Cytotoxicity assays, immunoblotting, indirect immunofluorescence and live imaging were used to study drug resistance, apoptosis, mitotic arrest, microtubule formation, and microtubule dynamics. Results MCF-7TXT cells were demonstrated to be cross resistant to vinca alkaloids, but were more sensitive to treatment with colchicine compared to parental non-resistant MCF-7CC cells. Cytotoxicity assays indicated that the IC50 of MCF-7TXT cell to vinorelbine and vinblastine was more than 6 and 3 times higher, respectively, than that of MCF-7CC cells. By contrast, the IC50 of MCF-7TXT cell for colchincine was 4 times lower than that of MCF-7CC cells. Indirect immunofluorescence showed that all MTAs induced the disorganization of microtubules and the chromatin morphology and interestingly each with a unique pattern. In terms of microtubule and chromain morphology, MCF

  1. Extended MHD Modeling of Tearing-Driven Magnetic Relaxation

    NASA Astrophysics Data System (ADS)

    Sauppe, Joshua

    2016-10-01

    Driven plasma pinch configurations are characterized by the gradual accumulation and episodic release of free energy in discrete relaxation events. The hallmark of this relaxation in a reversed-field pinch (RFP) plasma is flattening of the parallel current density profile effected by a fluctuation-induced dynamo emf in Ohm's law. Nonlinear two-fluid modeling of macroscopic RFP dynamics has shown appreciable coupling of magnetic relaxation and the evolution of plasma flow. Accurate modeling of RFP dynamics requires the Hall effect in Ohm's law as well as first order ion finite Larmor radius (FLR) effects, represented by the Braginskii ion gyroviscous stress tensor. New results find that the Hall dynamo effect from < J × B > / ne can counter the MHD effect from - < V × B > in some of the relaxation events. The MHD effect dominates these events and relaxes the current profile toward the Taylor state, but the opposition of the two dynamos generates plasma flow in the direction of equilibrium current density, consistent with experimental measurements. Detailed experimental measurements of the MHD and Hall emf terms are compared to these extended MHD predictions. Tracking the evolution of magnetic energy, helicity, and hybrid helicity during relaxation identifies the most important contributions in single-fluid and two-fluid models. Magnetic helicity is well conserved relative to the magnetic energy during relaxation. The hybrid helicity is dominated by magnetic helicity in realistic low-beta pinch conditions and is also well conserved. Differences of less than 1 % between magnetic helicity and hybrid helicity are observed with two-fluid modeling and result from cross helicity evolution through ion FLR effects, which have not been included in contemporary relaxation theories. The kinetic energy driven by relaxation in the computations is dominated by velocity components perpendicular to the magnetic field, an effect that had not been predicted. Work performed at

  2. Spontaneous Reconnection Onset in the Magnetotail: Kinetic and MHD Pictures

    NASA Astrophysics Data System (ADS)

    Sitnov, M. I.; Merkin, V. G.

    2014-12-01

    The mechanism of the reconnection onset in planetary magnetotails has been a topic of hot debate for more than three decades. At the kinetic level of description the key problem is a seemingly universal stability of the collisionless tearing mode when electrons are magnetized by the magnetic field normal to the current sheet. This effect can be eliminated in 2D equilibria with magnetic flux accumulated at the anti-sunward end of the tail. However, the resulting instability seen in 2D PIC simulations with open boundaries differs from the classical tearing mode because its main effect is the formation of dipolarization fronts, i. e., regions of an enhanced normal magnetic field rather than the reversal of its sign. Strong tailward gradients of the normal magnetic field characteristic of fronts suggest that they can be destroyed in 3D by buoyancy and flapping instabilities. However, 3D PIC simulations show that buoyancy and flapping motions can neither destroy nor change critically the near-2D picture of the front evolution, although they do significantly disturb it. Modeling and understanding of this kinetic picture of the reconnection onset in MHD terms is critically important for incorporating the explosive reconnection physics into global models of the magnetosphere and solar corona. A key to this has become the recognition that tail current sheets with accumulated flux regions can also be unstable with respect to an ideal analog of the tearing mode, which has a similar structure of the electromagnetic field and plasma perturbations but preserves the original magnetic field topology. MHD simulations with high Lundquist number confirm the existence of such "pseudo-tearing" instability regimes. Non-MHD effects, including different motions of electron and ion species as well as the ion Landau dissipation transform these ideal MHD motions into the tearing/slippage instability obtained in PIC simulations.

  3. Effects of water molecules of Ar-Cs MHD disk generator operated with strong MHD interaction

    SciTech Connect

    Ishikawa, M.; Kosugi, A.; Inui, Y.; Kabashima, S.

    1998-07-01

    Effects of water molecule impurity are studied on performance of a disk type MHD generator operated with Ar-Cs weakly ionized plasma. To reveal phenomena for a wide range of operation conditions, time-dependent one-dimensional analyses are carried out, where an up-wind, second order Chakravarthy TVD scheme is applied for the gasdynamics, while a Galerkin FEM is used for the electrodynamics. A simplified model is used for the water molecule impurity, where total effects of nonelastic collision between electrons and water molecules are estimated by the collision loss factor of electrons and also the electron momentum-transfer collision frequency is taken into account. The collision loss factor of electrons and the electron momentum-transfer collision frequency are taken from references, and the loss factor is assumed to be 700 independently of the electron temperature. On the Fuji-1 facilities at Tokyo Institute Technology, Japan, series of experiment A4105 were carried out with the Disk F-4 generator. Ar was heated with the heat-exchanger heated by the natural gas-air combustion and the metal cesium was used as the seeding material, while SCM maintained the magnetic field of 4.7 T at the center of disk and the very strong MHD interaction was realized. The thermal input was about 3 MW, the electrical output was about 500 kW with the enthalpy extraction ratio of about 17%. The numerical analyses have shown that the water molecule enhances the ionization instability at the low voltage loading because of insufficient Joule heating for electrons. The generator performance is degraded and the strong MHD interaction between the unstable plasma and the flow field induces slow and fast moving shock waves, leading to the very complicated flow field. The fast and slow moving shocks collide with each other, merge into a sharp shock moving downward, and then the shock front moves back slightly to maintain the pressure balance, collides again with another weak moving shock, and

  4. CORHEL MHD Modeling in Support of Solar Dynamics Observatory

    NASA Astrophysics Data System (ADS)

    Linker, Jon A.; Riley, P.; Mikic, Z.; Lionello, R.; Titov, V.; Wijaya, J.

    2010-05-01

    CORHEL - for Corona-Heliosphere - is a coupled set of models and tools for quantitatively modeling the ambient solar corona and solar wind in various approximations. The coronal MHD code MAS in CORHEL has been used to produce routine polytropic solutions for all of the Carrington rotations during the STEREO mission (available at www.predsci.com). The MAS code can also be used to produce solutions that include energy transport (radiative losses, anisotropic thermal conduction, and coronal heating) in the transition region and solar corona. This more accurate representation of energy flow allows us to compute simulated EUV and X-ray emission and compare directly with observations. We refer to this as the thermodynamic MHD model. In this paper, we describe the production of thermodynamic MHD solutions as part of CORHEL. When sufficiently calibrated data are available, the solutions will use magnetic maps derived from HMI magnetograms. These solutions will be made routinely available in support of the Solar Dynamics Observatory (SDO) mission, and will allow comparison with emission observations from AIA when emission kernels become available. Work supported by the LWS Strategic Capabilities Program (NASA, NSF, and AFOSR), CISM (NSF), HTP (NASA) and the HMI team.

  5. Three-dimensional parametric study for MHD marine propulsion

    SciTech Connect

    Doss, E.D. ); Roy, G.D. )

    1990-01-01

    The performance of MHD seawater thrusters have been investigated using a three-dimensional MHD flow model. The model incorporates the interaction between the flow fields and the electrical fields inside the thruster. A parametric study has been performed using the three-dimensional MHD flow model to analyze the performance of continuous electrode seawater thrusters under different operating parameters. The effects of these parameters on the fluid flow characteristics, and on the thruster efficiency have been investigated. Those parameters include the magnetic field (10--20 T), thruster diameter (1--2 m), surface roughness (0--2 mm), flow velocity (5--30 m/s), and the electric load factor (1--10). The results of the three-dimensional computations indicate that the velocity profiles are flatter over the sidewalls in comparison to the velocity profiles over the electrode walls. However such differences are not significant. The results of the parametric study show that the thruster electrical efficiency increases with the strength of the magnetic field and thruster diameter, and decreases with the flow velocity and surface roughness. 8 refs, 8 figs., 1 tab.

  6. Parametric analysis of closed cycle magnetohydrodynamic (MHD) power plants

    NASA Technical Reports Server (NTRS)

    Owens, W.; Berg, R.; Murthy, R.; Patten, J.

    1981-01-01

    A parametric analysis of closed cycle MHD power plants was performed which studied the technical feasibility, associated capital cost, and cost of electricity for the direct combustion of coal or coal derived fuel. Three reference plants, differing primarily in the method of coal conversion utilized, were defined. Reference Plant 1 used direct coal fired combustion while Reference Plants 2 and 3 employed on site integrated gasifiers. Reference Plant 2 used a pressurized gasifier while Reference Plant 3 used a ""state of the art' atmospheric gasifier. Thirty plant configurations were considered by using parametric variations from the Reference Plants. Parametric variations include the type of coal (Montana Rosebud or Illinois No. 6), clean up systems (hot or cold gas clean up), on or two stage atmospheric or pressurized direct fired coal combustors, and six different gasifier systems. Plant sizes ranged from 100 to 1000 MWe. Overall plant performance was calculated using two methodologies. In one task, the channel performance was assumed and the MHD topping cycle efficiencies were based on the assumed values. A second task involved rigorous calculations of channel performance (enthalpy extraction, isentropic efficiency and generator output) that verified the original (task one) assumptions. Closed cycle MHD capital costs were estimated for the task one plants; task two cost estimates were made for the channel and magnet only.

  7. MHD magnet technology development program summary, September 1982

    SciTech Connect

    Not Available

    1983-11-01

    The program of MHD magnet technology development conducted for the US Department of Energy by the Massachusetts Institute of Technology during the past five years is summarized. The general strategy is explained, the various parts of the program are described and the results are discussed. Subjects covered include component analysis, research and development aimed at improving the technology base, preparation of reference designs for commercial-scale magnets with associated design evaluations, manufacturability studies and cost estimations, the detail design and procurement of MHD test facility magnets involving transfer of technology to industry, investigations of accessory subsystem characteristics and magnet-flow-train interfacing considerations and the establishment of tentative recommendations for design standards, quality assurance procedures and safety procedures. A systematic approach (framework) developed to aid in the selection of the most suitable commercial-scale magnet designs is presented and the program status as of September 1982 is reported. Recommendations are made for future work needed to complete the design evaluation and selection process and to provide a sound technological base for the detail design and construction of commercial-scale MHD magnets. 85 references.

  8. Identification of lifestyle patterns, including sleep deprivation, associated with insulin resistance in children: the Healthy Growth Study.

    PubMed

    Androutsos, O; Moschonis, G; Mavrogianni, C; Roma-Giannikou, E; Chrousos, G P; Kanaka-Gantenbein, C; Manios, Y

    2014-03-01

    Although diet, physical activity (PA), sedentary behavior and sleep deprivation are factors that have been individually associated with insulin resistance (IR) in childhood, the combined effect of these lifestyle behaviors has not been examined yet. The current study aimed to examine the association of lifestyle patterns with IR, combining all these indices, in children. Socio-economic, demographic, anthropometric (body weight, height and waist circumference), biochemical (plasma glucose and serum insulin), clinical (pubertal stage) and lifestyle (dietary intake, PA level and sleeping habits) data were collected from a representative sample of 2026 children (50.1% girls) aged 9-13 years in Greece. Homeostasis model assessment (HOMA-IR) was calculated, and principal component analysis was used to identify lifestyle patterns, combining all these lifestyle indices. In multivariable regression analyses, the lifestyle pattern characterized by more screen time, shorter sleep duration and higher consumption of sugared beverages was positively associated with HOMA-IR (β=0.043; P=0.040), whereas the pattern characterized by more time spent on moderate-to-vigorous PA (MVPA) and more frequent eating occasions was inversely associated with HOMA-IR (β=-0.061; P=0.003). In logistic regression analyses, children with 72.2 min/day of MVPA and 5.05 eating occasions/day and children with 141.8 min/day of MVPA and 5.22 eating occasions/day were less likely of being insulin resistant based on HOMA-IR, compared with children with 20.0 min/day of MVPA and 4.09 eating occasions/day. A lifestyle pattern of >72 min of MVPA and 5 eating occasions/day was associated with reduced likelihood of IR in children.

  9. 17th Workshop on MHD Stability Control: addressing the disruption challenge for ITER

    NASA Astrophysics Data System (ADS)

    Buttery, Richard

    2013-08-01

    This annual workshop on magnetohydrodynamic stability control was held on 5-7 November 2012 at Columbia University in the city of New York, in the aftermath of a violent hydrodynamic instability event termed 'Hurricane Sandy'. Despite these challenging circumstances, Columbia University managed an excellent meeting, enabling the full participation of the community. This Workshop has been held since 1996 to help in the development of understanding and control of magnetohydrodynamic (MHD) instabilities for future fusion reactors. It covers a wide range of stability topics—from disruptions, to tearing modes, error fields, edge-localized modes (ELMs), resistive wall modes (RWMs) and ideal MHD—spanning many device types (tokamaks, stellarators and reversed field pinches) to identify commonalities in the physics and a means of control. The theme for 2012 was 'addressing the disruption challenge for ITER', and thus the first day had a heavy focus on both the avoidance and mitigation of disruptions in ITER. Key elements included understanding how to apply 3D fields to maintain stability, as well as managing the disruption process itself through mitigating loads in the thermal quench and handling so called 'runaway electrons'. This culminated in a panel discussion on the disruption mitigation strategy for ITER, which noted that heat load asymmetries during the thermal quench appear to be an artifact of MHD processes, and that runaway electron generation may be inevitable, suggesting research should focus on control and dissipation of the runaway beam. The workshop was combined this year with the annual US-Japan MHD Workshop, with a special section looking more deeply at 'Fundamentals of 3D Perturbed Equilibrium Control', with interesting sessions on 3D equilibrium reconstruction, RWM physics, novel control concepts such as non-magnetic sensing, adaptive control, q < 2 tokamak operation, and the effects of flow. The final day turned to tearing mode interactions

  10. NEWTONIAN AND NON-NEWTONIAN MAGNETIC-FIELD RELAXATIONS IN SOLAR-CORONAL MHD

    SciTech Connect

    Low, B. C.

    2013-05-01

    This paper treats the relaxation of a magnetic field into a minimum-energy force-free state in a cold (pressure-less) viscous fluid, under the frozen-in condition of perfect electrical conductivity and letting the viscosity-dissipated energy be completely lost. A non-Newtonian fluid in popular use is studied in relation to the Newtonian viscous fluid, as two alternative numerical means to (1) construct force-free fields representing solar coronal structures in realistic geometry and (2) investigate the Parker theory of spontaneous formation of electric current sheets as a basic MHD process. Faraday's induction equation imposes an independent condition on the fluid velocity at rigid, perfectly conducting boundaries. This boundary condition is quite compatible with Newtonian mechanics but not with the non-Newtonian fluid model where velocity is equated to the Lorentz force with a free, positive multiplicative-factor. This defining property gives rise to unphysical or artificial singularities not previously known that are completely distinct from the physically admissible singularities representing the current sheets of the Parker theory. In particular, the non-Newtonian fluid takes a magnetic field with neutral points from any one of a continuum of initial states into an unphysical state instead of the proper force-free end-state accessible by Newtonian relaxation. The validity of previously published MHD results based on this non-Newtonian fluid, including some counterclaims against the Parker theory, is dubious. Investigating the Parker theory requires numerical relaxation models capable of anticipating and accurately describing inevitable current-sheet singularities. By including a weak resistivity to dissipate the inevitable current sheets as they form, the field can change topology intermittently to seek a terminal force-free state free of singularities. The minimum-energy state of this more complete model corresponds to the long-lived relaxed structures in the

  11. MHD equilibria with diamagnetic effects

    NASA Astrophysics Data System (ADS)

    Tessarotto, M.; Zorat, R.; Johnson, J. L.; White, R. B.

    1997-11-01

    An outstanding issue in magnetic confinement is the establishment of MHD equilibria with enhanced flow shear profiles for which turbulence (and transport) may be locally effectively suppressed or at least substantially reduced with respect to standard weak turbulence models. Strong flows develop in the presence of equilibrium E× B-drifts produced by a strong radial electric field, as well as due to diamagnetic contributions produced by steep equilibrium radial profiles of number density, temperature and the flow velocity itself. In the framework of a kinetic description, this generally requires the construction of guiding-center variables correct to second order in the relevant expansion parameter. For this purpose, the Lagrangian approach developed recently by Tessarotto et al. [1] is adopted. In this paper the conditions of existence of such equilibria are analyzed and their basic physical properties are investigated in detail. 1 - M. Pozzo, M. Tessarotto and R. Zorat, in Theory of fusion Plasmas, E.Sindoni et al. eds. (Societá Italiana di Fisica, Editrice Compositori, Bologna, 1996), p.295.

  12. MHD Integrated Topping Cycle Project

    SciTech Connect

    Not Available

    1992-02-01

    This fourteenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period November 1, 1990 to January 31, 1991. Testing of the High Pressure Cooling Subsystem electrical isolator was completed. The PEEK material successfully passed the high temperature, high pressure duration tests (50 hours). The Combustion Subsystem drawings were CADAM released. The procurement process is in progress. An equipment specification and RFP were prepared for the new Low Pressure Cooling System (LPCS) and released for quotation. Work has been conducted on confirmation tests leading to final gas-side designs and studies to assist in channel fabrication.The final cathode gas-side design and the proposed gas-side designs of the anode and sidewall are presented. Anode confirmation tests and related analyses of anode wear mechanisms used in the selection of the proposed anode design are presented. Sidewall confirmation tests, which were used to select the proposed gas-side design, were conducted. The design for the full scale CDIF system was completed. A test program was initiated to investigate the practicality of using Avco current controls for current consolidation in the power takeoff (PTO) regions and to determine the cause of past current consolidation failures. Another important activity was the installation of 1A4-style coupons in the 1A1 channel. A description of the coupons and their location with 1A1 channel is presented herein.

  13. MHD waveguides in space plasma

    SciTech Connect

    Mazur, N. G.; Fedorov, E. N.; Pilipenko, V. A.

    2010-07-15

    The waveguide properties of two characteristic formations in the Earth's magnetotail-the plasma sheet and the current (neutral) sheet-are considered. The question of how the domains of existence of different types of MHD waveguide modes (fast and slow, body and surface) in the (k, {omega}) plane and their dispersion properties depend on the waveguide parameters is studied. Investigation of the dispersion relation in a number of particular (limiting) cases makes it possible to obtain a fairly complete qualitative pattern of all the branches of the dispersion curve. Accounting for the finite size of perturbations across the wave propagation direction reveals new additional effects such as a change in the critical waveguide frequencies, the excitation of longitudinal current at the boundaries of the sheets, and a change in the symmetry of the fundamental mode. Knowledge of the waveguide properties of the plasma and current sheets can explain the occurrence of preferred frequencies in the low-frequency fluctuation spectra in the magnetotail. In satellite observations, the type of waveguide mode can be determined from the spectral properties, as well as from the phase relationships between plasma oscillations and magnetic field oscillations that are presented in this paper.

  14. Reconstruction of Plasma Equilibria and Projected Stabilization of Global MHD Modes in KSTAR

    NASA Astrophysics Data System (ADS)

    Park, Y. S.; Sabbagh, S. A.; Bialek, J. M.; Berkery, J. W.; Jeon, Y. M.; Hahn, S. H.; Lee, S. G.; You, K.-. I.; Park, H. K.; Evans, T. E.; Eidietis, N.; Walker, M.; Leuer, J.

    2010-11-01

    Experimental equilibria of the KSTAR tokamak with plasma current up to 0.34 MA were reconstructed using EFIT. Vessel currents were included by fitting estimated values based on loop voltage measurements and effective resistances from 2 and 3-D vacuum model calculations including a double-walled vessel with large port penetrations and passive stabilizers. Active and passive stabilization of global MHD instabilities for operation above the no-wall beta limit is also projected. The stabilization is applied using a set of segmented internal coils called in-vessel control coils (IVCCs). Passive stability of the resistive wall mode and power requirement for its active stabilization are investigated including conductive casing structures covering the IVCC, and noise effects. The potential for ELM mitigation by resonant magnetic perturbations is also examined by using the TRIP3D code. Favorable configurations of the IVCC based on the Chirikov parameter are determined using a combination of all IVCCs (midplane and off-midplane coils) with a dominant n = 2 field configuration.

  15. Performance of Combustion Disk MHD Generators.

    NASA Astrophysics Data System (ADS)

    Jenkins, Marion Karl

    of Hall fields were investigated using external voltage augmentation, and electric fields of 9 KV/m were observed in the channel with no evidence of breakdown. The analytical work consisted of the development of a two-dimensional computer program to predict boundary layer phenomena in disk generators, including the effects of turbulence, variable gas properties and MHD interaction. The numerical results show the effect of the variable MHD body force across the insulating wall boundary layer, giving rise to boundary layer velocities higher than those in the core. This leads to greater skin friction and heat transfer losses than what would be predicted with a quasi -one dimensional model. Calculations carried out for baseload -sized generators show the expected dependence of boundary layer behavior on channel operating conditions such as wall temperature, swirl, magnetic field strength and channel loading.

  16. Comparison of four methods, including semi-automated rep-PCR, for the typing of vancomycin-resistant Enterococcus faecium.

    PubMed

    Bourdon, Nancy; Lemire, Astrid; Fines-Guyon, Marguerite; Auzou, Michel; Périchon, Bruno; Courvalin, Patrice; Cattoir, Vincent; Leclercq, Roland

    2011-01-01

    We have assessed the performance of semi-automated rep-PCR (Diversilab®) and multilocus sequence typing (MLST) in comparison to pulsed-field gel electrophoresis (PFGE) for typing a collection of 29 epidemiologically characterized vancomycin-resistant Enterococcus faecium (VRE). Sixteen strains that harbored the Tn1546 element were typed by PCR mapping. The discriminative power of the typing methods was calculated by the Simpson's index of diversity, and the concordance between methods was evaluated by the Kendall's coefficient of concordance. Semi-automated rep-PCR appeared as discriminative as PFGE and was further compared with PFGE for typing 67 VRE isolated during a hospital outbreak. Rep-PCR appeared to be more discriminative than PFGE for this second set of strains. Reproducibility of DiversiLab® was also tested against 35 selected isolates. Only three showed less than 97% similarity, indicating high reproducibility at this level of discrimination. In conclusion, semi-automated rep-PCR is a useful tool for rapid screening of VRE isolates during an outbreak, although cost of the system may be limiting for routine implementation. PFGE, which remains the reference method, should be used for confirmation and evaluation of the genetic relatedness of epidemic isolates.

  17. In vitro antibacterial and chemical properties of essential oils including native plants from Brazil against pathogenic and resistant bacteria.

    PubMed

    Barbosa, Lidiane Nunes; Probst, Isabella da Silva; Andrade, Bruna Fernanda Murbach Teles; Alves, Fernanda Cristina Bérgamo; Albano, Mariana; da Cunha, Maria de Lourdes Ribeiro de Souza; Doyama, Julio Toshimi; Rall, Vera Lúcia Mores; Fernandes Júnior, Ary

    2015-01-01

    The antimicrobials products from plants have increased in importance due to the therapeutic potential in the treatment of infectious diseases. Therefore, we aimed to examine the chemical characterisation (GC-MS) of essential oils (EO) from seven plants and measure antibacterial activities against bacterial strains isolated from clinical human specimens (methicillin-resistant Staphylococcus aureus (MRSA) and sensitive (MSSA), Escherichia coli, Pseudomonas aeruginosa, Salmonella Typhimurium) and foods (Salmonella Enteritidis). Assays were performed using the minimal inhibitory concentration (MIC and MIC90%) (mg/mL) by agar dilution and time kill curve methods (log CFU/mL) to aiming synergism between EO. EO chemical analysis showed a predominance of terpenes and its derivatives. The highest antibacterial activities were with Cinnamomun zeylanicum (0.25 mg/mL on almost bacteria tested) and Caryophyllus aromaticus EO (2.40 mg/mL on Salmonella Enteritidis), and the lowest activity was with Eugenia uniflora (from 50.80 mg/mL against MSSA to 92.40 mg/mL against both Salmonella sources and P. aeruginosa) EO. The time kill curve assays revealed the occurrence of bactericide synergism in combinations of C. aromaticus and C. zeylanicum with Rosmarinus. officinalis. Thus, the antibacterial activities of the EO were large and this can also be explained by complex chemical composition of the oils tested in this study and the synergistic effect of these EO, yet requires further investigation because these interactions between the various chemical compounds can increase or reduce (antagonism effect) the inhibitory effect of essential oils against bacterial strains.

  18. Control of linear modes in cylindrical resistive magnetohydrodynamics with a resistive wall, plasma rotation, and complex gain

    SciTech Connect

    Brennan, D. P.; Finn, J. M.

    2014-10-15

    Feedback stabilization of magnetohydrodynamic (MHD) modes in a tokamak is studied in a cylindrical model with a resistive wall, plasma resistivity, viscosity, and toroidal rotation. The control is based on a linear combination of the normal and tangential components of the magnetic field just inside the resistive wall. The feedback includes complex gain, for both the normal and for the tangential components, and it is known that the imaginary part of the feedback for the former is equivalent to plasma rotation [J. M. Finn and L. Chacon, Phys. Plasmas 11, 1866 (2004)]. The work includes (1) analysis with a reduced resistive MHD model for a tokamak with finite β and with stepfunction current density and pressure profiles, and (2) computations with a full compressible visco-resistive MHD model with smooth decreasing profiles of current density and pressure. The equilibria are stable for β = 0 and the marginal stability values β{sub rp,rw} < β{sub rp,iw} < β{sub ip,rw} < β{sub ip,iw} (resistive plasma, resistive wall; resistive plasma, ideal wall; ideal plasma, resistive wall; and ideal plasma, ideal wall) are computed for both models. The main results are: (a) imaginary gain with normal sensors or plasma rotation stabilizes below β{sub rp,iw} because rotation suppresses the diffusion of flux from the plasma out through the wall and, more surprisingly, (b) rotation or imaginary gain with normal sensors destabilizes above β{sub rp,iw} because it prevents the feedback flux from entering the plasma through the resistive wall to form a virtual wall. A method of using complex gain G{sub i} to optimize in the presence of rotation in this regime with β > β{sub rp,iw} is presented. The effect of imaginary gain with tangential sensors is more complicated but essentially destabilizes above and below β{sub rp,iw}.

  19. Dipole Alignment in Rotating MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.; Fu, Terry; Morin, Lee

    2012-01-01

    We present numerical results from long-term CPU and GPU simulations of rotating, homogeneous, magnetohydrodynamic (MHD) turbulence, and discuss their connection to the spherically bounded case. We compare our numerical results with a statistical theory of geodynamo action that has evolved from the absolute equilibrium ensemble theory of ideal MHD turbulence, which is based on the ideal MHD invariants are energy, cross helicity and magnetic helicity. However, for rotating MHD turbulence, the cross helicity is no longer an exact invariant, although rms cross helicity becomes quasistationary during an ideal MHD simulation. This and the anisotropy imposed by rotation suggests an ansatz in which an effective, nonzero value of cross helicity is assigned to axisymmetric modes and zero cross helicity to non-axisymmetric modes. This hybrid statistics predicts a large-scale quasistationary magnetic field due to broken ergodicity , as well as dipole vector alignment with the rotation axis, both of which are observed numerically. We find that only a relatively small value of effective cross helicity leads to the prediction of a dipole moment vector that is closely aligned (less than 10 degrees) with the rotation axis. We also discuss the effect of initial conditions, dissipation and grid size on the numerical simulations and statistical theory.

  20. Corrosion and arc erosion in MHD channels

    NASA Astrophysics Data System (ADS)

    Rosa, R. J.; Pollina, R. J.

    1990-07-01

    The objective of this task is to study the corrosion and arc erosion of MHD materials in a cooperative effort with, and to support, the MHD topping cycle program. Materials tested in the Avco Research Laboratory/Textron facility, or materials which have significant MHD importance, will be analyzed to document their physical deterioration. Conclusions shall be drawn about their wear mechanisms and lifetime in the MHD environment with respect to the following issues; sulfur corrosion, electrochemical corrosion, and arc erosion. The impact of any materials or slag conditions on the level of power output and on the level of leakage current in the MHD channel will also be noted, where appropriate. The work performed to date in the analysis of channel gas side materials has served to identify and clarify the respective environments to which the various materials are subjected and identified a performance ranking of materials. For high voltage intercathode gaps, which show the most severe wear, the materials rank in the order from best to worst: W, Mo, 90WCu, 97W2Fe1Ni, 75WCu, and Cr. We have shown data which indicates that lifetime is sensitive to gap voltage. Therefore for conditions under which iron oxide addition maintains low voltage intercathode gaps 75WCu becomes an excellent cathode material.

  1. Edge biasing effects on MHD instabilities and plasma response to external magnetic perturbations in HBT-EP

    NASA Astrophysics Data System (ADS)

    Debono, Bryan; Maurer, Dave; Mauel, Michael; L., Jeff; Daisuke, S.; Niko, R.; Navratil, Gerald; A., Sarah; B., Pat; Pedersen, Thomas; HBT-EP Team

    2011-10-01

    A biased electrode inserted into a tokamak plasma edge can be used to apply torque on the plasma and change the rotation rate of MHD instabilities, including the resistive wall mode (RWM). RWM's in HBT-EP have a natural frequency of +4-9 kHz, however with appropriate bias the plasma rotation can be adjusted both positively and negatively. We present a study of the effect of biased plasma rotation on MHD instabilities; a comparison is made between plasma rotation rate and the plasma response to external resonant magnetic perturbations (RMP). The Boozer tokamak plasma reluctance equation ρ = -(1/s - iα + 1) 1/Lp suggests that the plasma response to RMP's is greatly enhanced as the toroidal torque dissapation coefficient α --> 0 . Moderate biasing (~ 50V) slows down the RWM rotation to 2-3kHz, and an increase in the plasma responsivity to RMP's is seen. Strong positive bias (~ + 300 V) accelerates the mode in the direction opposite to its natural rotation at ~ -40 kHz. At this high rotation frequency the mode is being dragged at too rapid a rate for it to penetrate the wall. Therefore, the conducting shells behave like an ideal wall and a saturated ideal external kink is observed instead of a RWM.

  2. A stochastic approach to uncertainty in the equations of MHD kinematics

    SciTech Connect

    Phillips, Edward G.; Elman, Howard C.

    2015-03-01

    The magnetohydrodynamic (MHD) kinematics model describes the electromagnetic behavior of an electrically conducting fluid when its hydrodynamic properties are assumed to be known. In particular, the MHD kinematics equations can be used to simulate the magnetic field induced by a given velocity field. While prescribing the velocity field leads to a simpler model than the fully coupled MHD system, this may introduce some epistemic uncertainty into the model. If the velocity of a physical system is not known with certainty, the magnetic field obtained from the model may not be reflective of the magnetic field seen in experiments. Additionally, uncertainty in physical parameters such as the magnetic resistivity may affect the reliability of predictions obtained from this model. By modeling the velocity and the resistivity as random variables in the MHD kinematics model, we seek to quantify the effects of uncertainty in these fields on the induced magnetic field. We develop stochastic expressions for these quantities and investigate their impact within a finite element discretization of the kinematics equations. We obtain mean and variance data through Monte Carlo simulation for several test problems. Toward this end, we develop and test an efficient block preconditioner for the linear systems arising from the discretized equations.

  3. Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC).

    PubMed

    Barry, Garrett S; Cheang, Maggie C; Chang, Hector Li; Kennecke, Hagen F

    2016-04-05

    A prospective study was conducted to identify biomarkers associated with resistance to panitumumab monotherapy in patients with metastatic colorectal cancer (mCRC). Patients with previously treated, codon 12/13 KRAS wt, mCRC were prospectively administered panitumumab 6 mg/kg IV q2weeks. Of 34 panitumumab-treated patients, 11 (32%) had progressive disease at 8 weeks and were classified as non-responders. A Nanostring nCounter-based assay identified a 5-gene expression signature (ERBB2, MLPH, IRX3, MYRF, and KLK6) associated with panitumumab resistance (P = 0.001). Immunohistochemistry and in situ hybridization determined that the HER2 (ERBB2) protein was overexpressed in 4/11 non-responding and 0/21 responding cases (P = 0.035). Two non-responding tumors had ERBB2 gene amplification only, and one demonstrated both ERBB2 amplification and mutation. A non-codon 12/13 KRAS mutation occurred in one panitumumab-resistant patient and was mutually exclusive with ERBB2/HER2 abnormalities. This study identifies a 5-gene signature associated with non-response to single agent panitumumab, including a subgroup of non-responders with evidence of aberrant ERBB2/HER2 signaling. KRAS wt tumors resistant to EGFRi may be identified by gene signature analysis, and the HER2 pathway plays an important role in resistance to therapy.

  4. Towards Integrated Pulse Detonation Propulsion and MHD Power

    NASA Technical Reports Server (NTRS)

    Litchford, Ron J.; Thompson, Bryan R.; Lineberry, John T.

    1999-01-01

    The interest in pulse detonation engines (PDE) arises primarily from the advantages that accrue from the significant combustion pressure rise that is developed in the detonation process. Conventional rocket engines, for example, must obtain all of their compression from the turbopumps, while the PDE provides additional compression in the combustor. Thus PDE's are expected to achieve higher I(sub sp) than conventional rocket engines and to require smaller turbopumps. The increase in I(sub sp) and the decrease in turbopump capacity must be traded off against each other. Additional advantages include the ability to vary thrust level by adjusting the firing rate rather than throttling the flow through injector elements. The common conclusion derived from these aggregated performance attributes is that PDEs should result in engines which are smaller, lower in cost, and lighter in weight than conventional engines. Unfortunately, the analysis of PDEs is highly complex due to their unsteady operation and non-ideal processes. Although the feasibility of the basic PDE concept has been proven in several experimental and theoretical efforts, the implied performance improvements have yet to be convincingly demonstrated. Also, there are certain developmental issues affecting the practical application of pulse detonation propulsion systems which are yet to be fully resolved. Practical detonation combustion engines, for example, require a repetitive cycle of charge induction, mixing, initiation/propagation of the detonation wave, and expulsion/scavenging of the combustion product gases. Clearly, the performance and power density of such a device depends upon the maximum rate at which this cycle can be successfully implemented. In addition, the electrical energy required for direct detonation initiation can be significant, and a means for direct electrical power production is needed to achieve self-sustained engine operation. This work addresses the technological issues associated

  5. In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains

    PubMed Central

    West, Joshua; Ito, Akinobu; Ito-Horiyama, Tsukasa; Nakamura, Rio; Sato, Takafumi; Rittenhouse, Stephen; Tsuji, Masakatsu; Yamano, Yoshinori

    2015-01-01

    S-649266 is a novel siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. Two sets of clinical isolate collections were used to evaluate the antimicrobial activity of S-649266 against Enterobacteriaceae. These sets included 617 global isolates collected between 2009 and 2011 and 233 β-lactamase-identified isolates, including 47 KPC-, 49 NDM-, 12 VIM-, and 8 IMP-producers. The MIC90 values of S-649266 against the first set of Escherichia coli, Klebsiella pneumoniae, Serratia marcescens, Citrobacter freundii, Enterobacter aerogenes, and Enterobacter cloacae isolates were all ≤1 μg/ml, and there were only 8 isolates (1.3%) among these 617 clinical isolates with MIC values of ≥8 μg/ml. In the second set, the MIC values of S-649266 were ≤4 μg/ml against 109 strains among 116 KPC-producing and class B (metallo) carbapenemase-producing strains. In addition, S-649266 showed MIC values of ≤2 μg/ml against each of the 13 strains that produced other types of carbapenemases such as SME, NMC, and OXA-48. The mechanisms of the decreased susceptibility of 7 class B carbapenemase-producing strains with MIC values of ≥16 μg/ml are uncertain. This is the first report to demonstrate that S-649266, a novel siderophore cephalosporin, has significant antimicrobial activity against Enterobacteriaceae, including strains that produce carbapenemases such as KPC and NDM-1. PMID:26574013

  6. Modeling of substorm development with a kinematic effect by the global MHD simulations

    NASA Astrophysics Data System (ADS)

    den, Mitsue; Fujita, Shigeru; Tanaka, Takashi; Horiuchi, Ritoku

    Magnetic reconnection is considered to play an important role in space phenomena such as substorm in the Earth's magnetosphere. Recently, Tanaka and Fujita reproduced substorm evoution process by numerical simulation with the global MHD code. In the MHD framework, the dissipation model is used for modeling of the kinetic effects. They found that the normalized reconnection viscosity, one of the dessipation model employed there, gave a large effect for the substorm development though that viscosity was assumed to be a constant parameter. It is well known that magnetric reconnection is controlled by microscopic kinetic mechanism. Horiuchi et al. investigated the roles of microscopic plasma instabilities on the violation of the frozen-in condition by examining the force balance equation based on explicit electromagnetic particle simulation for an ion-scale current sheet, and concluded that the growth of drift kink instability can create anomalous resistivity leading to the excitation of collisionless reconnection. They estimated the effective resistivity based on the particle simulation data. In this paper, we perform substorm simulation by using the global MHD code with this anomalous resistivity obtained in their microscopic approach istead of the emprical resistivity model, and investigate the relationship between the substorm development and the anomalous resistivity model.

  7. "Ideal" tearing and the transition to fast reconnection in the weakly collisional MHD and EMHD regimes

    NASA Astrophysics Data System (ADS)

    Del Sarto, Daniele; Pucci, Fulvia; Tenerani, Anna; Velli, Marco

    2016-03-01

    This paper discusses the transition to fast growth of the tearing instability in thin current sheets in the collisionless limit where electron inertia drives the reconnection process. It has been previously suggested that in resistive MHD there is a natural maximum aspect ratio (ratio of sheet length and breadth to thickness) which may be reached for current sheets with a macroscopic length L, the limit being provided by the fact that the tearing mode growth time becomes of the same order as the Alfvén time calculated on the macroscopic scale. For current sheets with a smaller aspect ratio than critical the normalized growth rate tends to zero with increasing Lundquist number S, while for current sheets with an aspect ratio greater than critical the growth rate diverges with S. Here we carry out a similar analysis but with electron inertia as the term violating magnetic flux conservation: previously found scalings of critical current sheet aspect ratios with the Lundquist number are generalized to include the dependence on the ratio de2/L2, where de is the electron skin depth, and it is shown that there are limiting scalings which, as in the resistive case, result in reconnecting modes growing on ideal time scales. Finite Larmor radius effects are then included, and the rescaling argument at the basis of "ideal" reconnection is proposed to explain secondary fast reconnection regimes naturally appearing in numerical simulations of current sheet evolution.

  8. MHD simulations of supernova driven ISM turbulence

    NASA Astrophysics Data System (ADS)

    Gressel, Oliver; Ziegler, Udo

    The dynamic evolution of the (stratified) turbulent interstellar medium (ISM) is simulated utilizing a three-dimensional MHD model including various physical effects. The computational domain covers a box of 0.5x0.5x2.0 kpc at a resolution of typically 128x128x1024 grid cells. The model includes (constant kinematic) viscosity and magnetic diffusivity. The adiabatic equation of state is supplemented by a parameterized heating- and cooling-function allowing for thermal instability (TI). The update due to heating and cooling is implemented implicitly using a Patankar-type discretization. Turbulence is driven by supernova explosions which are modelled as local injections of thermal energy, smeared over three standard-deviations of a Gaussian support with FWHM of 20pc. Supernova rates are adopted for typical cited values. Within our model we make a distinction between Type I and Type II SNe. Latter are statistically clustered by the (artificial) constraint that the density at the explosion site be above average (with respect to a horizontal slab) - former are spatially uncorrelated. The dual-energy feature of the conservative NIRVANA-code is used to tackle the extreme ratio of kinetic to internal energy that arises from the violent energy input. We stress the importance of using a conservative scheme to properly transfer the injected energy to kinetic motion. The model also includes a differentially rotating background (with shearing boundary conditions in radial direction) as well as vertical stratification. The initial density and pressure profiles are in hydrostatic equilibrium with respect to the equation of state given by the radiative equilibrium. Including z-dependent heating rates this leads to a considerable deviation from usual isothermal initial models. The primary focus of this work is on the galactic dynamo and the generation of large-scale magnetic fields. As a secondary target we are also interested in general properties of the ISM that are of importance

  9. Slow shock and rotational discontinuity in MHD and Hall MHD models with anisotropic pressure

    NASA Astrophysics Data System (ADS)

    Hau, L.-N.; Wang, B.-J.

    2016-07-01

    Pressure anisotropy may modify the characteristics of magnetohydrodynamic (MHD) waves, in particular, the slow mode wave and the corresponding shocks and discontinuities. In this study the formation of slow shocks (SSs) in anisotropic plasmas is examined by solving the gyrotropic MHD and Hall MHD equations numerically for one-dimensional Riemann problem. The MHD shocks and discontinuities are generated by imposing a finite normal magnetic field on the Harris type current sheet with a guide magnetic By component. It is shown that anomalous SSs moving faster than the intermediate wave or with positive density-magnetic field correlation may be generated in gyrotropic MHD and Hall MHD models. Moreover, for some parameter values SSs may exhibit upstream wave trains with right-handed polarization in contrast with the earlier prediction that SSs shall possess downstream left-hand polarized wave trains based on the isotropic Hall MHD theory. For the cases of By ≠ 0, SSs with increased density and decreased magnetic field followed by noncoplanar intermediate mode or rotational discontinuity (RD)-like structures similar to the compound SS-RD structures observed in space plasma environments may possibly form in symmetric and asymmetric current layers. The Walén relation of these anomalous RDs without the correction of pressure anisotropy may significantly be violated.

  10. Simulation of wave interactions with MHD

    SciTech Connect

    Batchelor, Donald B; Abla, G; Bateman, Glenn; Bernholdt, David E; Berry, Lee A; Bonoli, P.; Bramley, R; Breslau, J.; Chance, M.; Chen, J.; Choi, M.; Elwasif, Wael R; Fu, GuoYong; Harvey, R. W.; Jaeger, Erwin Frederick; Jardin, S. C.; Jenkins, T; Keyes, David E; Klasky, Scott A; Kruger, Scott; Ku, Long-Poe; Lynch, Vickie E; McCune, Douglas; Ramos, J.; Schissel, D.; Schnack,; Wright, J.

    2008-07-01

    The broad scientific objectives of the SWIM (Simulation of Wave Interaction with MHD) project are twofold: (1) improve our understanding of interactions that both radio frequency (RF) wave and particle sources have on extended-MHD phenomena, and to substantially improve our capability for predicting and optimizing the performance of burning plasmas in devices such as ITER: and (2) develop an integrated computational system for treating multiphysics phenomena with the required flexibility and extensibility to serve as a prototype for the Fusion Simulation Project. The Integrated Plasma Simulator (IPS) has been implemented. Presented here are initial physics results on RF effects on MHD instabilities in tokamaks as well as simulation results for tokamak discharge evolution using the IPS.

  11. MHD energy fluxes for late type dwarfs

    NASA Technical Reports Server (NTRS)

    Rosner, R.; Musielak, Z. E.

    1987-01-01

    The efficiency of MHD wave generation by turbulent motions in stratified stellar atmospheres with embedded uniform magnetic fields is calculated. In contradiction with previous results, it is shown that there is no significant increase in the efficiency of wave generation because of the presence of magnetic fields, at least within the theory's limits of applicability. It is shown that MHD energy fluxes for late-type stars are less than those obtained for acoustic waves in a magnetic-field-free atmosphere, and do not vary enough for a given spectral type in order to explain observed UV and X-ray fluxes. Thus, the results show that MHD energy fluxes obtained if stellar surface magnetic fields are uniform cannot explain the observed stellar coronal emissions.

  12. MHD Modeling of the Transition Region Using Realistic Transport Coefficients

    NASA Astrophysics Data System (ADS)

    Goodman, Michael L.

    1997-05-01

    Most of the transition region (TR) consists of a collision dominated plasma. The dissipation and transport of energy in such a plasma is accurately described by the well known classical transport coefficients which include the electrical and thermal conductivity, viscosity, and thermo- electric tensors. These tensors are anisotropic and are functions of local values of temperature, density, and magnetic field. They may be used in an MHD model to obtain a self consistent, physically realistic description of the TR. The physics of kinetic processes is included in the MHD model through the transport coefficients. As a first step in studying heating and cooling processes in the TR in a realistic, quantitative manner, a 1.5 dimensional, steady state MHD model with a specified temperature profile is considered. The momentum equation includes the inertial, pressure gradient, Lorentz, and gravitational forces. The Ohm's law includes the exact expressions for the electrical conductivity and thermo- electric tensors. The electrical conductivity relates the generalized electric field to the conduction current density while the thermo-electric tensor relates the temperature gradient to the thermo-electric current density. The total current density is the sum of the two. It is found that the thermo-electric current density can be as large as the conduction current density, indicating that thermo-electric effects are probably important in modeling the dynamics of energy dissipation, such as wave dissipation, in the TR. Although the temperature gradient is in the vertical direction, the thermo-electric current density is in the horizontal direction, indicating the importance of the effects of anisotropic transport. The transport coefficients are valid for all magnetic field strengths, and so may be used to study the physics of weakly as well as strongly magnetized regions of the TR. Numerical examples are presented.

  13. HBT-EP Program: Active MHD Mode Dynamics & Control

    NASA Astrophysics Data System (ADS)

    Navratil, G. A.; Angelini, S.; Bialek, J.; Byrne, P. J.; Cole, A. J.; Debono, B. A.; Hughes, P. E.; Levesque, J. P.; Mauel, M. E.; Peng, Q.; Rhodes, D. J.; Stoafer, C. C.; Hansen, C. J.

    2014-10-01

    The HBT-EP active mode control research program aims to: (i) quantify external kink dynamics and multimode response to applied magnetic perturbations, (ii) understand the relationship between control coil configuration, conducting and ferritic wall effects, and active feedback control, and (iii) explore advanced feedback algorithms. Biorthogonal decomposition is used to observe multiple simultaneous resistive wall modes (RWM). Improved visualization of MHD kink mode structure is achieved using a tangential fast camera viewing visible light emission that augments magnetic probe data. A 512 core GPU-based low latency (14 μs) MIMO control system uses 96 inputs and 64 outputs for Adaptive Control of RWMs. An in-vessel adjustable ferritic wall was used to study ferritic RWMs with enhanced MHD response. A biased electrode in the plasma was used to control the rotation of external kinks. A Thomson scattering diagnostic measures Te and ne at 3 spatial points, soon to be extended to 10 points. A quasi-linear sharp-boundary model of the plasma's multimode response to error fields is developed to determine harmful error field structures and associated NTV and resonant torques. USDOE Grant DE-FG-02-86ER53222.

  14. MHD dynamo and charge separation for the Reversed Field Pinch

    NASA Astrophysics Data System (ADS)

    Cappello, Susanna; Bonfiglio, Daniele; Franck Escande, Dominique

    2004-11-01

    The reversed field pinch (RFP) is a toroidal configuration for magnetic confinement characterized by a plasma current strong enough to excite a kink instability. Though according to the standard paradigm developed in the 80'-90' the ensuing MHD turbulence would be intrinsic to the RFP dynamo, more recent studies go beyond this view. Three-dimensional visco-resistive MHD simulations display a transition from multiple helicity (MH) states to single helicity (SH) steady states [1] when dissipation is increased. These SH states provide a laminar dynamo for the RFP. The present work unveils the features of these SH states by performing a detailed analysis of numerical simulations. Since this state is stationary, the electric field is curl-free. Poisson equation reveals a charge separation, which is small enough to be consistent with the quasi-neutrality condition. This charge separation is shown to play a key role in the dynamo effect, since the related electrostatic field produces a drift velocity which is the main part of the dynamo velocity field. This physical interpretation of the dynamo, involving a leading role of the charge separation, can be extended to the quasi single helicity (QSH) states found in RFP devices as well as to turbulent MH states. [1] S. Cappello and D.F. Escande , Physical Review Letters 85-18 (2000) 3838

  15. High-. beta. operation and MHD (magnetohydrodynamic) activity on TFTR

    SciTech Connect

    McGuire, K.

    1990-04-01

    Magnetohydrodynamic (MHD) activity within three zones (core, half- radius, and edge) of TFTR (Plasma Physics and Controlled Nuclear Fusion Research (1986), (IAEA, Vienna, 1987), Vol. 1, P. 51) tokamak plasmas are discussed. Near the core of the plasma column, sawteeth are often observed. Two types of sawteeth are studied in detail: one with complete, and the other with incomplete magnetic reconnection. Their characteristics are determined by the shape of the q profile. Near the half-radius the m/n = 3/2 and 2/1 resistive ballooning modes are found to correlate with a beta collapse. The pressure and the pressure gradient at the mode rational surface are found to play an important role in stability. MHD activity is also studied at the plasma edge during limiter H-modes. The Edge Localized Mode (ELMs) are found to have a precursor mode with a frequency between 50--200 kHz and a mode number m/n = 1/0. The mode does not show a ballooning structure. While these instabilities have been studied on many other machines, on TFTR the studies have been extended to high pressure (plasma pressure greater than 4 {times} 10{sup 5} Pa) and low collisionality. 16 refs., 3 figs.

  16. MHD modeling of dense plasma focus electrode shape variation

    NASA Astrophysics Data System (ADS)

    McLean, Harry; Hartman, Charles; Schmidt, Andrea; Tang, Vincent; Link, Anthony; Ellsworth, Jen; Reisman, David

    2013-10-01

    The dense plasma focus (DPF) is a very simple device physically, but results to date indicate that very extensive physics is needed to understand the details of operation, especially during the final pinch where kinetic effects become very important. Nevertheless, the overall effects of electrode geometry, electrode size, and drive circuit parameters can be informed efficiently using MHD fluid codes, especially in the run-down phase before the final pinch. These kinds of results can then guide subsequent, more detailed fully kinetic modeling efforts. We report on resistive 2-d MHD modeling results applying the TRAC-II code to the DPF with an emphasis on varying anode and cathode shape. Drive circuit variations are handled in the code using a self-consistent circuit model for the external capacitor bank since the device impedance is strongly coupled to the internal plasma physics. Electrode shape is characterized by the ratio of inner diameter to outer diameter, length to diameter, and various parameterizations for tapering. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  17. Neon Induced MHD Activity in FTU

    NASA Astrophysics Data System (ADS)

    Botrugno, A.; Buratti, P.; Marinucci, M.; Mazzotta, C.; Pucella, G.; Romano, A.; Sozzi, C.

    The m/n=2/1 tearing instability driven by rapid increasing of the current density gradient near the q=2 radius induced by Ne puffing has discussed for different Frascati Tokamak Upgraded (FTU) L-mode ohmic plasmas. The dynamic of modes can be divided in three phases. The formation and dynamic of MHD activity strictly depends on the amount of Ne in plasma, for this reason, Ne puffing represents a very efficient method to deliberately induce formation of repeatable MHD targets for different experimental needs.

  18. Explosively-driven magnetohydrodynamic (MHD) generator studies

    SciTech Connect

    Agee, F.J.; Lehr, F.M.; Vigil, M.; Kaye, R.; Gaudet, J.; Shiffler, D.

    1995-08-01

    Plasma jet generators have been designed and tested which used an explosive driver and shocktube with a rectangular cross section that optimize the flow velocity and electrical conductivity. The latest in a series of designs has been tested using a reactive load to diagnose the electrical properties of the MHD generator/electromagnet combination. The results of these tests indicate that the plasma jet/MHD generator design does generate a flow velocity greater than 25 km/s and produces several gigawatts of pulsed power in a very small package size. A larger, new generator design is also presented.

  19. In vitro and in vivo evaluation of fluoroquinolone resistance associated with DNA gyrase mutations in Francisella tularensis, including in tularaemia patients with treatment failure.

    PubMed

    Sutera, V; Hoarau, G; Renesto, P; Caspar, Y; Maurin, M

    2017-09-01

    Fluoroquinolones (FQs) are highly effective for treating tularaemia, a zoonosis caused by Francisella tularensis, but failures and relapses remain common in patients with treatment delay or immunocompromised status. FQ-resistant strains of F. tularensis harboring mutations in the quinolone-resistance determining region (QRDR) of gyrA and gyrB, the genes encoding subunits A and B of DNA gyrase, have been selected in vitro. Such mutants have never been isolated from humans as this microorganism is difficult to culture. In this study, the presence of FQ-resistant mutants of F. tularensis was assessed in tularaemia patients using combined culture- and PCR-based approaches. We analyzed 42 F. tularensis strains and 82 tissue samples collected from 104 tularaemia cases, including 32 (30.7%) with FQ treatment failure or relapse. Forty F. tularensis strains and 55 clinical samples were obtained before any FQ treatment, while 2 strains and 15 tissue samples were collected after treatment. FQ resistance was evaluated by the minimum inhibitory concentration (MIC) for the bacterial strains, and by newly developed PCR-based methods targeting the gyrA and gyrB QRDRs for both the bacterial strains and the clinical samples. None of the F. tularensis strains displayed an increased MIC compared with FQ-susceptible controls. Neither gyrA nor gyrB QRDR mutation was found in bacterial strains and tissue samples tested, including those from patients with FQ treatment failure or relapse. Further phenotypic and genetic resistance traits should be explored to explain the poor clinical response to FQ treatment in such tularaemia patients. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  20. The Effect of Ivermectin in Seven Strains of Aedes aegypti (Diptera: Culicidae) Including a Genetically Diverse Laboratory Strain and Three Permethrin Resistant Strains

    PubMed Central

    Deus, K. M.; Saavedra-rodriguez, K.; Butters, M. P.; Black, W. C.; Foy, B. D.

    2014-01-01

    Seven different strains of Aedes aegypti (L.), including a genetically diverse laboratory strain, three laboratory-selected permethrin-resistant strains, a standard reference strain, and two recently colonized strains were fed on human blood containing various concentrations of ivermectin. Ivermectin reduced adult survival, fecundity, and hatch rate of eggs laid by ivermectin-treated adults in all seven strains. The LC50 of ivermectin for adults and the concentration that prevented 50% of eggs from hatching was calculated for all strains. Considerable variation in adult survival after an ivermectin-bloodmeal occurred among strains, and all three permethrin-resistant strains were significantly less susceptible to ivermectin than the standard reference strain. The hatch rate after an ivermectin bloodmeal was less variable among strains, and only one of the permethrin-resistant strains differed significantly from the standard reference strain. Our studies suggest that ivermectin induces adult mortality and decreases the hatch rate of eggs through different mechanisms. A correlation analysis of log-transformed LC50 among strains suggests that permethrin and ivermectin cross-resistance may occur. PMID:22493855

  1. MHD and Kinetic Modeling of the Ionospheres of Venus and Mars

    SciTech Connect

    Shinagawa, H.; Terada, N.

    2009-06-16

    It is widely recognized that both Venus and Mars possess no significant global intrinsic magnetic fields, and that the solar wind interacts directly with the upper atmospheres and ionospheres of Venus and Mars. In addition, local crustal magnetic fields are also present in various regions at Mars, suggesting that some regions of the Martian ionosphere are influenced not only by the solar wind but also by the crustal magnetic field. Previous studies have suggested that the basic structures of the ionospheres of the planets can be described by fluid and MHD(magnetohydrodynamic) processes. Various models of the ionospheres of Venus and Mars based on the MHD formulation have been constructed during the last two decades. Although the MHD approach has been successful in reproducing the ionospheres of the planets, some studies have indicated that MHD modeling is not necessarily appropriate in the regions of the topside ionosphere, the ionopause, and the magnetosheath, where the ion kinetic processes are likely to play an important role. The kinetic processes in the topside ionosphere might have significant influences even in the lower ionosphere. Thanks to a great progress made for computer power as well as the efficiency of calculations of the hybrid model, high-resolution kinetic models of the solar wind interaction with Venus and Mars, which self-consistently include the ionosphere, have been developed. In this paper, status of MHD and kinetic modeling of the ionospheres of Venus and Mars is briefly reviewed.

  2. Multi-fluid MHD study of the solar wind interaction with Pluto

    NASA Astrophysics Data System (ADS)

    Dong, C.; Ma, Y.; McComas, D. J.; Bhattacharjee, A.; Zirnstein, E.; Toth, G.; Luhmann, J. G.; Wang, L.

    2016-12-01

    The study of the solar wind interaction with Pluto's upper atmosphere has triggered a great of interest in recent years. The Solar Wind Around Pluto (SWAP) instrument onboard New Horizon (NH) spacecraft has provided a wealth of detailed and quantitative information about Pluto and its interaction with the tenuous solar wind out at 33 AU. The SWAP data reveals Pluto's unique interaction with the solar wind as a hybrid of comet-like and the Venus/Mars-like interactions. While SWAP data has provided many of the key results, a lot of details are still missing merely based on NH flyby observations. In order to further investigate the solar wind-Pluto interaction from a global point of view, we develop a 3-D multi-fluid MHD (MF-MHD) model. The MF-MHD model solves separate continuity, momentum and energy equations for each ion species. We adopt the 1-D modeled neutral atmosphere, which is based on NH observations, as the MF-MHD input. Photoionization, charge exchange and electron impact ionization are all included in the MF-MHD model. We will study the ion escape rate, and Pluto's magnetosphere and heavy ion tail structure. We will also do some data-model comparisons. This work has the potential to improve our understanding of present day Pluto's unique solar wind interaction and thus enhance the science returned from the NH mission.

  3. Smoothed MHD equations for numerical simulations of ideal quasi-neutral gas dynamic flows

    NASA Astrophysics Data System (ADS)

    Popov, Mikhail V.; Elizarova, Tatiana G.

    2015-11-01

    We introduce a mathematical model and related numerical method for numerical modeling of ideal magnetohydrodynamic (MHD) gas flows as an extension of previously known quasi-gasdynamic (QGD) equations. This approach is based on smoothing, or averaging of the original MHD equation system over a small time interval that leads to a new equation system, named quasi-MHD, or QMHD system. The QMHD equations are closely related to the original MHD system except for additional strongly non-linear dissipative τ-terms with a small parameter τ as a factor. The τ-terms depend on the solution itself and decrease in regions with the small space gradients of the solution. In this sense the QMHD system could be regarded as an approach with adaptive artificial dissipation. The QMHD is a generalization of regularized (or quasi-) gas dynamic equation system suggested in last three decades. In the QMHD numerical method the evolution of all physical variables is presented in a non-split divergence form. Divergence-free evolution of the magnetic field provides by using a constrained transport method based on Faraday's law of induction. Accuracy and convergence of the QMHD method is verified on a wide set of standard MHD tests including the 3D Orszag-Tang vortex flow.

  4. Estimating a planetary magnetic field with time-dependent global MHD simulations using an adjoint approach

    NASA Astrophysics Data System (ADS)

    Nabert, Christian; Othmer, Carsten; Glassmeier, Karl-Heinz

    2017-05-01

    The interaction of the solar wind with a planetary magnetic field causes electrical currents that modify the magnetic field distribution around the planet. We present an approach to estimating the planetary magnetic field from in situ spacecraft data using a magnetohydrodynamic (MHD) simulation approach. The method is developed with respect to the upcoming BepiColombo mission to planet Mercury aimed at determining the planet's magnetic field and its interior electrical conductivity distribution. In contrast to the widely used empirical models, global MHD simulations allow the calculation of the strongly time-dependent interaction process of the solar wind with the planet. As a first approach, we use a simple MHD simulation code that includes time-dependent solar wind and magnetic field parameters. The planetary parameters are estimated by minimizing the misfit of spacecraft data and simulation results with a gradient-based optimization. As the calculation of gradients with respect to many parameters is usually very time-consuming, we investigate the application of an adjoint MHD model. This adjoint MHD model is generated by an automatic differentiation tool to compute the gradients efficiently. The computational cost for determining the gradient with an adjoint approach is nearly independent of the number of parameters. Our method is validated by application to THEMIS (Time History of Events and Macroscale Interactions during Substorms) magnetosheath data to estimate Earth's dipole moment.

  5. MHD and 2-Fluid Stability of DIII-D Shot #96043 using the NIMROD Code

    NASA Astrophysics Data System (ADS)

    Schnack, Dalton; Kruger, Scott; Kim, C. C.; Turnbull, Alan

    2010-11-01

    DIII-D shot #96043 exhibits sawtooth free periods during NB/RF heating. These periods are terminated by ``giant sawtooth'' crashes. This discharge has formed the basis for computational evaluation of the Porcelli model [1]. We have begun [2] to use this discharge in a verification and validation campaign for energetic particle model the NIMROD code [3]. The ability to perform and understand resistive and extended MHD computations is necessary for a proper V & V study of the energetic particle model. At t=1900 msec, unstable modes are the 1/1 ideal kink mode, a resistive 2/2 mode and a number of high-n localized rippling modes with q ˜3 (near the separatrix). With resistive MHD the high-n modes can be stabilized by a combination of viscosity profile and anisotropic thermal conductivity. When 2-fluid are introduced new high-n localized mode appear. Linear results for all models and nonlinear results for resistive MHD are presented.[0pt] [1] M. Choi, A. D. Turnbull, V. S. Chan, et al., Phys. Plasmas 14, 112517 (2007). [2] D. D. Schnack, et al., Bull. Am. Phys. Soc. 54, paper S1.00056 (Abstract Only) (2009). [3] C. C. Kim and the NIMROD Team, Phys. Plasmas 15, 072507 (2008).

  6. Modeling of Feedback Stabilization of External MHD Modes in Toroidal Geometry

    NASA Astrophysics Data System (ADS)

    Chu, M. S.; Chance, M. S.; Okabayashi, M.

    2000-10-01

    The intelligent shell feedback scheme(C.M. Bishop, Plasma Phys. Contr. Nucl. Fusion 31), 1179 (1989). seeks to utilize external coils to suppress the unstable MHD modes slowed down by the resistive shell. We present a new formulation and numerical results of the interaction between the plasma and its outside vacuum region, with complete plasma response and the inclusion of a resistive vessel in general toroidal geometry. This is achieved by using the Green's function technique, which is a generalization of that previously used for the VACUUM(M.S. Chance, Phys. Plasmas 4), 2161 (1997). code and coupled with the ideal MHD code GATO. The effectiveness of different realizations of the intelligent shell concept is gauged by their ability to minimize the available free energy to drive the MHD mode. Computations indicate poloidal coverage of 30% of the total resistive wall surface area and 6 or 7 segments of ``intelligent coil'' arrays superimposed on the resistive wall will allow recovery of up to 90% the effectiveness of the ideal shell in stabilizing the ideal external kink.

  7. MHD (magnetohydrodynamics) instabilities in simple plasma configuration

    SciTech Connect

    Manheimer, W.M.; Lashmore-Davies, C.

    1984-01-01

    This work provides what, we hope, is a relatively simple, self contained description of MHD instabilities in plasmas with simple configurations. By simple configuration, we mean a plasma in which all quantities vary in only one spatial direction. We deal with such plasmas here because we want to emphasize the basic physics of MHD instabilities. Although some fusion devices are inherently two or three dimensional in nature, there are others, specifically tokamaks and reversed field pinches which are, to good approximation, one dimensional. Also, these devices both display a wealth of complex MHD activity which can be fruitfully discussed. One deceptive aspect of MHD instabilities is that the simplest ones are extremely easy to understand. However more complicated instabilities, for instance in a plasma where both an axial and azimuthal field are present are much more difficult to visualize; but they are also much more interesting. This work is divided into two parts. Chapters 2-9 describe linear theory and chapters 10-15 describe the nonlinear theory. The latter part is naturally much more speculative than the former because less is known about nonlinear theory.

  8. Featured Image: Tests of an MHD Code

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-09-01

    Creating the codes that are used to numerically model astrophysical systems takes a lot of work and a lot of testing! A new, publicly available moving-mesh magnetohydrodynamics (MHD) code, DISCO, is designed to model 2D and 3D orbital fluid motion, such as that of astrophysical disks. In a recent article, DISCO creator Paul Duffell (University of California, Berkeley) presents the code and the outcomes from a series of standard tests of DISCOs stability, accuracy, and scalability.From left to right and top to bottom, the test outputs shown above are: a cylindrical Kelvin-Helmholtz flow (showing off DISCOs numerical grid in 2D), a passive scalar in a smooth vortex (can DISCO maintain contact discontinuities?), a global look at the cylindrical Kelvin-Helmholtz flow, a Jupiter-mass planet opening a gap in a viscous disk, an MHD flywheel (a test of DISCOs stability), an MHD explosion revealing shock structures, an MHD rotor (a more challenging version of the explosion), a Flock 3D MRI test (can DISCO study linear growth of the magnetorotational instability in disks?), and a nonlinear 3D MRI test.Check out the gif below for a closer look at each of these images, or follow the link to the original article to see even more!CitationPaul C. Duffell 2016 ApJS 226 2. doi:10.3847/0067-0049/226/1/2

  9. MHD Ballooning Instability in the Plasma Sheet

    SciTech Connect

    C.Z. Cheng; S. Zaharia

    2003-10-20

    Based on the ideal-MHD model the stability of ballooning modes is investigated by employing realistic 3D magnetospheric equilibria, in particular for the substorm growth phase. Previous MHD ballooning stability calculations making use of approximations on the plasma compressibility can give rise to erroneous conclusions. Our results show that without making approximations on the plasma compressibility the MHD ballooning modes are unstable for the entire plasma sheet where beta (sub)eq is greater than or equal to 1, and the most unstable modes are located in the strong cross-tail current sheet region in the near-Earth plasma sheet, which maps to the initial brightening location of the breakup arc in the ionosphere. However, the MHD beq threshold is too low in comparison with observations by AMPTE/CCE at X = -(8 - 9)R(sub)E, which show that a low-frequency instability is excited only when beq increases over 50. The difficulty is mitigated by considering the kinetic effects of ion gyrorad ii and trapped electron dynamics, which can greatly increase the stabilizing effects of field line tension and thus enhance the beta(sub)eq threshold [Cheng and Lui, 1998]. The consequence is to reduce the equatorial region of the unstable ballooning modes to the strong cross-tail current sheet region where the free energy associated with the plasma pressure gradient and magnetic field curvature is maximum.

  10. Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: a systematic review with meta-analysis

    PubMed Central

    2014-01-01

    Current recommendations for the prevention of type 2 diabetes advise modification of diet and exercise behaviors including both aerobic and resistance training. However, the efficacy of multi-component interventions involving a combination of these three components has not been established. The aims of this review were to systematically review and meta-analyze the evidence on multi-component (diet + aerobic exercise + resistance training) lifestyle interventions for type 2 diabetes prevention. Eight electronic databases (Medline, Embase, SportDiscus, Web of Science, CINAHL, Informit health collection, Cochrane library and Scopus) were searched up to June 2013. Eligible studies 1) recruited prediabetic adults or individuals at risk of type 2 diabetes; 2) conducted diet and exercise [including both physical activity/aerobic and resistance training] programs; and 3) reported weight and plasma glucose outcomes. In total, 23 articles from eight studies were eligible including five randomized controlled trials, one quasi-experimental, one two-group comparison and one single-group pre-post study. Four studies had a low risk of bias (score ≥ 6/10). Median intervention length was 12 months (range 4–48 months) with a follow-up of 18 months (range 6.5 - 48 months). The diet and exercise interventions varied slightly in terms of their specific prescriptions. Meta-analysis favored interventions over controls for weight loss (-3.79 kg [-6.13, -1.46; 95% CI], Z = 3.19, P = 0.001) and fasting plasma glucose (-0.13 mmol.L-1 [-0.24, -0.02; 95% CI], Z = 2.42, P = 0.02). Diabetes incidence was only reported in two studies, with reductions of 58% and 56% versus control groups. In summary, multi-component lifestyle type 2 diabetes prevention interventions that include diet and both aerobic and resistance exercise training are modestly effective in inducing weight loss and improving impaired fasting glucose, glucose tolerance, dietary and exercise

  11. Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: a systematic review with meta-analysis.

    PubMed

    Aguiar, Elroy J; Morgan, Philip J; Collins, Clare E; Plotnikoff, Ronald C; Callister, Robin

    2014-01-15

    Current recommendations for the prevention of type 2 diabetes advise modification of diet and exercise behaviors including both aerobic and resistance training. However, the efficacy of multi-component interventions involving a combination of these three components has not been established. The aims of this review were to systematically review and meta-analyze the evidence on multi-component (diet + aerobic exercise + resistance training) lifestyle interventions for type 2 diabetes prevention. Eight electronic databases (Medline, Embase, SportDiscus, Web of Science, CINAHL, Informit health collection, Cochrane library and Scopus) were searched up to June 2013. Eligible studies 1) recruited prediabetic adults or individuals at risk of type 2 diabetes; 2) conducted diet and exercise [including both physical activity/aerobic and resistance training] programs; and 3) reported weight and plasma glucose outcomes. In total, 23 articles from eight studies were eligible including five randomized controlled trials, one quasi-experimental, one two-group comparison and one single-group pre-post study. Four studies had a low risk of bias (score ≥ 6/10). Median intervention length was 12 months (range 4-48 months) with a follow-up of 18 months (range 6.5-48 months). The diet and exercise interventions varied slightly in terms of their specific prescriptions. Meta-analysis favored interventions over controls for weight loss (-3.79 kg [-6.13, -1.46; 95% CI], Z = 3.19, P = 0.001) and fasting plasma glucose (-0.13 mmol.L⁻¹ [-0.24, -0.02; 95% CI], Z = 2.42, P = 0.02). Diabetes incidence was only reported in two studies, with reductions of 58% and 56% versus control groups. In summary, multi-component lifestyle type 2 diabetes prevention interventions that include diet and both aerobic and resistance exercise training are modestly effective in inducing weight loss and improving impaired fasting glucose, glucose tolerance, dietary and exercise outcomes

  12. Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648

    PubMed Central

    Suzuki, Yuuki; Shiraishi, Tsukasa; Honda, Hiroyuki; Shinagawa, Masaaki; Yamamoto, Soh; Ogasawara, Noriko; Takahashi, Hiroki; Takahashi, Satoshi; Tamura, Yutaka; Yokota, Shin-ichi

    2016-01-01

    ABSTRACT Tigecycline (TGC) is a last-line drug for multidrug-resistant Enterobacteriaceae. We investigated the mechanism(s) underlying TGC nonsusceptibility (TGC resistant/intermediate) in Escherichia coli clinical isolates. The MIC of TGC was determined for 277 fluoroquinolone-susceptible isolates (ciprofloxacin [CIP] MIC, <0.125 mg/liter) and 194 fluoroquinolone-resistant isolates (CIP MIC, >2 mg/liter). The MIC50 and MIC90 for TGC in fluoroquinolone-resistant isolates were 2-fold higher than those in fluoroquinolone-susceptible isolates (MIC50, 0.5 mg/liter versus 0.25 mg/liter; MIC90, 1 mg/liter versus 0.5 mg/liter, respectively). Two fluoroquinolone-resistant isolates (O25b:H4-ST131-H30R and O125:H37-ST48) were TGC resistant (MICs of 4 and 16 mg/liter, respectively), and four other isolates of O25b:H4-ST131-H30R and an isolate of O1-ST648 showed an intermediate interpretation (MIC, 2 mg/liter). No TGC-resistant/intermediate strains were found among the fluoroquinolone-susceptible isolates. The TGC-resistant/intermediate isolates expressed higher levels of acrA and acrB and had lower intracellular TGC concentrations than susceptible isolates, and they possessed mutations in acrR and/or marR. The MICs of acrAB-deficient mutants were markedly lower (0.25 mg/liter) than those of the parental strain. After continuous stepwise exposure to CIP in vitro, six of eight TGC-susceptible isolates had reduced TGC susceptibility. Two of them acquired TGC resistance (TGC MIC, 4 mg/liter) and exhibited expression of acrA and acrB and mutations in acrR and/or marR. In conclusion, a population of fluoroquinolone-resistant E. coli isolates, including major extraintestinal pathogenic lineages O25b:H4-ST131-H30R and O1-ST648, showed reduced susceptibility to TGC due to overexpression of the efflux pump AcrAB-TolC, leading to decreased intracellular concentrations of the antibiotics that may be associated with the development of fluoroquinolone resistance. PMID:27855067

  13. Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648.

    PubMed

    Sato, Toyotaka; Suzuki, Yuuki; Shiraishi, Tsukasa; Honda, Hiroyuki; Shinagawa, Masaaki; Yamamoto, Soh; Ogasawara, Noriko; Takahashi, Hiroki; Takahashi, Satoshi; Tamura, Yutaka; Yokota, Shin-Ichi

    2017-02-01

    Tigecycline (TGC) is a last-line drug for multidrug-resistant Enterobacteriaceae We investigated the mechanism(s) underlying TGC nonsusceptibility (TGC resistant/intermediate) in Escherichia coli clinical isolates. The MIC of TGC was determined for 277 fluoroquinolone-susceptible isolates (ciprofloxacin [CIP] MIC, <0.125 mg/liter) and 194 fluoroquinolone-resistant isolates (CIP MIC, >2 mg/liter). The MIC50 and MIC90 for TGC in fluoroquinolone-resistant isolates were 2-fold higher than those in fluoroquinolone-susceptible isolates (MIC50, 0.5 mg/liter versus 0.25 mg/liter; MIC90, 1 mg/liter versus 0.5 mg/liter, respectively). Two fluoroquinolone-resistant isolates (O25b:H4-ST131-H30R and O125:H37-ST48) were TGC resistant (MICs of 4 and 16 mg/liter, respectively), and four other isolates of O25b:H4-ST131-H30R and an isolate of O1-ST648 showed an intermediate interpretation (MIC, 2 mg/liter). No TGC-resistant/intermediate strains were found among the fluoroquinolone-susceptible isolates. The TGC-resistant/intermediate isolates expressed higher levels of acrA and acrB and had lower intracellular TGC concentrations than susceptible isolates, and they possessed mutations in acrR and/or marR The MICs of acrAB-deficient mutants were markedly lower (0.25 mg/liter) than those of the parental strain. After continuous stepwise exposure to CIP in vitro, six of eight TGC-susceptible isolates had reduced TGC susceptibility. Two of them acquired TGC resistance (TGC MIC, 4 mg/liter) and exhibited expression of acrA and acrB and mutations in acrR and/or marR In conclusion, a population of fluoroquinolone-resistant E. coli isolates, including major extraintestinal pathogenic lineages O25b:H4-ST131-H30R and O1-ST648, showed reduced susceptibility to TGC due to overexpression of the efflux pump AcrAB-TolC, leading to decreased intracellular concentrations of the antibiotics that may be associated with the development of fluoroquinolone resistance.

  14. Calculation of Magnetospheric Equilibria and Evolution of Plasma Bubbles with a New Finite-Volume MHD/Magnetofriction Code

    NASA Astrophysics Data System (ADS)

    Silin, I.; Toffoletto, F.; Wolf, R.; Sazykin, S. Y.

    2013-12-01

    We present a finite-volume MHD code for simulations of magnetospheric dynamics of the plasma sheet and the inner magnetosphere. The code uses staggered non-uniform Cartesian grids to preserve the divergence-free magnetic fields, along with various numerical approximations and flux limiters for the plasma variables. The code can be initialized with empirical magnetic field models, such as the Tsyganenko models along with pressure information from either the Tsyganenko-Mukai models, or observational data, such as DMSP pressure maps. Artificial "friction term" can be added to the momentum equation, which turns the MHD code into "magnetofriction" code which can be used to construct approximate equilibrium solutions. We demonstrate some applications for our code, in both the "magnetofriction" and MHD mode, including relaxation of the empirical models to equilibrium and the evolution of a plasma bubble in the near magnetotail. The latter MHD simulation results exhibit oscillations about their equilibrium position in agreement with recent observations.

  15. Coupled optimization of the channel and magnet coil configuration for a 200 MWe coal-fired MHD generator

    SciTech Connect

    Nishimura, Ryo; Aoki, Yoshiaki; Kayukawa, Naoyuki

    1993-12-31

    This paper discusses the effect of the cross-sectional shape of the magnet coil upon the reduction of the MHD channel length. The optimization for the cross-sectional shape of a magnet coil including an MHD channel is carried out for a 200 MWe coal fired supersonic Faraday-type MHD generator. It is shown that the channel and the coil length can be shortened more than 30% by the optimization of the coil shape in comparison with the case of the crescent shaped coil producing a uniform magnetic field, where the enthalpy extraction is effectively kept unchanged. Also, it is estimated that the capital cost for a stand alone commercial MHD/steam combined plant can be decreased more than 6% by this coil shape optimization.

  16. Prevalence and Characterization of Staphylococcus aureus, Including Methicillin-Resistant Staphylococcus aureus, Isolated from Bulk Tank Milk from Minnesota Dairy Farms

    PubMed Central

    Haran, K. P.; Godden, S. M.; Boxrud, D.; Jawahir, S.; Bender, J. B.

    2012-01-01

    Staphylococcus aureus is a common causative agent of bovine mastitis in dairy herds. The emergence of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals as well as the community is a significant and costly public health concern. S. aureus-related bovine mastitis is a common reason for therapeutic and/or prophylactic use of antibiotics on dairy farms. In this study, herd prevalence of S. aureus, including MRSA, was estimated from bulk tank milk (BTM) from Minnesota farms. A total of 150 pooled BTM samples from 50 farms, collected over 3 seasons (spring, summer, and fall of 2009), were assessed. Herd prevalence of methicillin-susceptible S. aureus (MSSA) was 84%, while MRSA herd prevalence was 4%. A total of 93 MSSA isolates and 2 MRSA isolates were recovered from 150 BTM samples. Antibiotic susceptibility testing of S. aureus isolates showed pansusceptibility in 54 isolates, resistance to a single antibiotic class in 21 isolates, resistance to two antibiotic classes in 13 isolates, and resistance to ≥3 antibiotics classes and thus multidrug resistance in 5 isolates. The two MRSA isolates displayed resistance to β-lactams, cephalosporins, and lincosamides and were multiresistant. Staphylococcal protein A gene (spa) typing identified spa types t529 and t034 most frequently among methicillin-susceptible isolates, while t121 was observed in MRSA isolates. Seven isolates, including the two MRSA isolates, produced staphylococcal enterotoxins B, C, D, and E on overnight culture. MRSA isolates were further genotyped using multilocus sequence typing (MLST) and pulsed-field gel electrophoresis (PFGE). Of the 2 MRSA isolates, one had a composite genotype profile of MLST ST 5-PFGE USA100-unknown spa type, which has been reported among hospital-associated MRSA isolates, while the second isolate carried the MLST ST 8-PFGE USA300-spa type t121 genotype, commonly identified among community-associated MRSA isolates. These results suggest that MRSA genotypes

  17. MHD simulations for investigating interaction processes between a CME and ambient solar wind

    NASA Astrophysics Data System (ADS)

    An, Junmo; Magara, Tetsuya

    2016-05-01

    The interaction between coronal mass ejections (CMEs) and ambient solar winds is one of the important issues of space weather because it affects the trajectory of a flying CME, which determines whether the CME hits the Earth and produces geomagnetic disturbances or not. In this study, two-step 3D magnetohydrodynamic (MHD) simulations including a spheromak-type CME and an ambient solar wind are performed to investigate their interaction processes such as deflection and rotation of a CME. We perform the 1st-step MHD simulation using averaged surface magnetic field data to construct a steady state with an ambient solar wind. A spheromak-type CME is then injected through the solar surface, and subsequent evolution is reproduced by performing the 2nd-step MHD simulation. We discuss key parameters that characterize interaction processes between a CME and ambient solar wind.

  18. Conceptual design study of potential early commercial MHD powerplant. Report of task 2 results

    NASA Technical Reports Server (NTRS)

    Hals, F. A.

    1981-01-01

    The conceptual design of one of the potential early commercial MHD power plants was studied. The plant employs oxygen enrichment of the combustion air and preheating of this oxygen enriched air to an intermediate temperature of 1200 F attainable with a tubular type recuperative heat exchanger. Conceptual designs of plant componets and equipment with performance, operational characteristics, and costs are reported. Plant economics and overall performance including full and part load operation are reviewed. The projected performance and estimated cost of this early MHD plant are compared to conventional power plants, although it does not offer the same high efficiency and low costs as the mature MHD power plant. Environmental aspects and the methods incorporated in plant design for emission control of sulfur and nitrogen are reviewed.

  19. A New Godunov Scheme for MHD, with Application to the MRI in disks

    NASA Astrophysics Data System (ADS)

    Stone, James M.; Gardiner, Thomas A.

    2005-09-01

    We describe a new numerical scheme for MHD which combines a higher order Godunov method (PPM) with Constrained Transport. The results from a selection of multidimensional test problems are presented. The complete test suite used to validate the method, as well as implementations of the algorithm in both F90 and C, are available from the web. A fully three-dimensional version of the algorithm has been developed, and is being applied to a variety of astrophysical problems including the decay of supersonic MHD turbulence, the nonlinear evolution of the MHD Rayleigh-Taylor instability, and the saturation of the magnetorotational instability in the shearing box. Our new simulations of the MRI represent the first time that a higher-order Godunov scheme has been applied to this problem, providing a quantitative check on the accuracy of previous results computed with ZEUS; the latter are found to be reliable.

  20. Conceptual design study of potential early commercial MHD powerplant. Report of task 2 results

    NASA Astrophysics Data System (ADS)

    Hals, F. A.

    1981-03-01

    The conceptual design of one of the potential early commercial MHD power plants was studied. The plant employs oxygen enrichment of the combustion air and preheating of this oxygen enriched air to an intermediate temperature of 1200 F attainable with a tubular type recuperative heat exchanger. Conceptual designs of plant componets and equipment with performance, operational characteristics, and costs are reported. Plant economics and overall performance including full and part load operation are reviewed. The projected performance and estimated cost of this early MHD plant are compared to conventional power plants, although it does not offer the same high efficiency and low costs as the mature MHD power plant. Environmental aspects and the methods incorporated in plant design for emission control of sulfur and nitrogen are reviewed.

  1. FTE Dependence on IMF Orientation and Presence of Hall Physics in Global MHD Simulations

    NASA Astrophysics Data System (ADS)

    Maynard, K. M.; Germaschewski, K.; Lin, L.; Raeder, J.

    2013-12-01

    Flux Transfer Events (FTEs) are poleward traveling flux ropes that form in the dayside magnetopause and represent significant coupling of the solar wind to the magnetosphere during times of southward IMF. In the 35 years since their discovery, FTEs have been extensively observed and modeled; however, there is still no consensus on their generation mechanism. Previous modeling efforts have shown that FTE occurrence and size depend on the resistivity model that is used in simulations and the structure of X-lines in the magnetopause. We use Hall OpenGGCM, a global Hall-MHD code, to study the formation and propagation of FTEs in the dayside magnetopause using synthetic solar wind conditions. We examine large scale FTE structure and nearby magnetic separators for a range of IMF clock angles and dipole tilts. In addition, we investigate how FTE formation and recurrence rate depends on the presence of the Hall term in the generalized Ohm's law compared with resistive MHD.

  2. Symmetry, Statistics and Structure in MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.

    2007-01-01

    Here, we examine homogeneous MHD turbulence in terms of truncated Fourier series. The ideal MHD equations and the associated statistical theory of absolute equilibrium ensembles are symmetric under P, C and T. However, the presence of invariant helicities, which are pseudoscalars under P and C, dynamically breaks this symmetry. This occurs because the surface of constant energy in phase space has disjoint parts, called components: while ensemble averages are taken over all components, a dynamical phase trajectory is confined to only one component. As the Birkhoff-Khinchin theorem tells us, ideal MHD turbulence is thus non-ergodic. This non-ergodicity manifests itself in low-wave number Fourier modes that have large mean values (while absolute ensemble theory predicts mean values of zero). Therefore, we have coherent structure in ideal MHD turbulence. The level of non-ergodicity and amount of energy contained in the associated coherent structure depends on the values of the helicities, as well as on the presence, or not, of a mean magnetic field and/or overall rotation. In addition to the well known cross and magnetic helicities, we also present a new invariant, which we call the parallel helicity, since it occurs when mean field and rotation axis are aligned. The question of applicability of these results to real (i.e., dissipative) MHD turbulence is also examined. Several long-time numerical simulations on a 64(exp 3) grid are given as examples. It is seen that coherent structure begins to form before decay dominates over nonlinearity. The connection of these results with inverse spectral cascades, selective decay, and magnetic dynamos is also discussed.

  3. Statistical properties of MHD fluctuations associated with high speed streams from HELIOS 2 observations

    NASA Technical Reports Server (NTRS)

    Bavassano, B.; Dobrowolny, H.; Fanfoni, G.; Mariani, F.; Ness, N. F.

    1981-01-01

    Helios 2 magnetic data were used to obtain several statistical properties of MHD fluctuations associated with the trailing edge of a given stream served in different solar rotations. Eigenvalues and eigenvectors of the variance matrix, total power and degree of compressibility of the fluctuations were derived and discussed both as a function of distance from the Sun and as a function of the frequency range included in the sample. The results obtained add new information to the picture of MHD turbulence in the solar wind. In particular, a dependence from frequency range of the radial gradients of various statistical quantities is obtained.

  4. HBT-EP Program: Active MHD Mode Dynamics & Control

    NASA Astrophysics Data System (ADS)

    Navratil, G. A.; Angelini, S.; Bialek, J.; Boozer, A. H.; Byrne, P.; Cole, A. J.; Debono, B.; Hammond, K.; Hughes, P.; Levesque, J. P.; Mauel, M. E.; Peng, Q.; Rath, N.; Rhodes, D.; Shiraki, D.; Stoafer, C.; Volpe, F. A.; Cziegler, I.; Paul, S.

    2012-10-01

    The HBT- EP active mode control research program aims to (i) quantify external kink dynamics and multimode response to applied magnetic perturbations, (ii) understand the relationship between control coil configuration, conducting and ferritic wall effects, and active feedback control effectiveness, and (iii) explore advanced feedback algorithms. Biorthogonal decomposition is used to observe multiple simultaneous resistive wall modes (RWM) with m<9 and n<5. Transitions were observed for m/n=4/1 to 3/1 accompanied by 7/2 to 6/2. Non-rigid mode behavior is observed with independent 3/1 and 6/2 RWMs. Active MHD spectroscopy is used to study 3/1 resonant field response showing linear, saturated, and ultimately, disruptive behavior as the external field amplitude is increased. Using an improved GPU based MIMO digital control system with VALEN 3D feedback modeling, we aim to optimize modular feedback coils to control instability growth near the ideal wall limit.

  5. 3-D MHD Simulation of Oscillating Field Current Drive

    NASA Astrophysics Data System (ADS)

    Ebrahimi, F.; Prager, S. C.; Wright, J. C.

    2000-10-01

    Oscillating Field Current Drive (OFCD) is a proposed low frequency steady-state current drive technique for the Reversed Field Pinch (RFP). In OFCD toroidal and poloidal oscillating electric fields are applied with 90^circ phase difference to inject magnetic helicity. In the present work, the 3-D nonlinear, resistive MHD code DEBS is used to simulate OFCD in relaxed RFP plasmas. The present simulations are at high Lundquist number S=10^5 and low spect ratio R/a=1.5. The physics issues investigated are the response of background magnetic fluctuations to the oscillating fields, the relative contributions of the tearing mode dynamo and the oscillating fields to the current profile, and the sustainment and control of the steady-state current profile. Initial results with low amplitude oscillating fields show the expected increase in magnetic helicity and current. Results with higher amplitude will also be presented.

  6. Ionization fronts in coupled MHD-gas simulations

    NASA Astrophysics Data System (ADS)

    Wilson, A. D.; Diver, D. A.

    2017-09-01

    Partially ionized plasmas are ubiquitous in both nature and the laboratory, and their behaviour is best described by models which take into account the interactions between the neutral and charged species. We present a new non-linear, 3-dimensional, finite difference Gas-MHD Interactions Code designed to solve simultaneously the time evolution of fluid equations of both species in the conservation form as well as collisional interactions between them via appropriate choices of source term; in particular, we present results from this code in simulating Alfvén ionization in a partially ionized plasma. In this fashion, larger changes in the ionization fraction than were addressable in the linear limit are possible. Alfvén ionization is shown to impart plasmas with an inherent resistance to rapid recombination, where the recombination itself is significant enough to drive relative motion between the ionised and neutral species at speeds in excess of the critical velocity.

  7. MHD modeling of DIII-D QH-mode discharges and comparison to observations

    NASA Astrophysics Data System (ADS)

    King, Jacob

    2016-10-01

    MHD modeling of DIII-D QH-mode discharges and comparison to observations Nonlinear NIMROD simulations, initialized from a reconstruction of a DIII-D QH-mode discharge with broadband MHD, saturate into a turbulent state, but do not saturate when flow is not included. This is consistent with the experimental results of the quiescent regime observed on DIII-D with broadband MHD activity [Garofalo et al., PoP (2015) and refs. within]. These ELM-free discharges have the normalized pedestal-plasma confinement necessary for burning-plasma operation on ITER. Relative to QH-mode operation with more coherent MHD activity, operation with broadband MHD tends to occur at higher densities and lower rotation and thus may be more relevant to ITER. The nonlinear NIMROD simulations require highly accurate equilibrium reconstructions. Our equilibrium reconstructions include the scrape-off-layer profiles and the measured toroidal and poloidal rotation profiles. The simulation develops into a saturated turbulent state and the n=1 and 2 modes become dominant through an inverse cascade. Each toroidal mode in the range of n=1-5 is dominant at a different time. The perturbations are advected and sheared apart in the counter-clockwise direction consistent with the direction of the poloidal flow inside the LCFS. Work towards validation through comparison to magnetic coil and Doppler reflectometry measurements is presented. Consistent with experimental observations during QH-mode, the simulated state leads to large particle transport relative to the thermal transport. Analysis shows that the phase of the density and temperature perturbations differ resulting in greater convective particle transport relative to the convective thermal transport. This work supported by the U.S. Department of Energy Office of Science and the SciDAC Center for Extended MHD Modeling under Contract Numbers DE-FC02-06ER54875, DE-FC02-08ER54972 and DE-FC02-04ER54698.

  8. Three-fluid, 3D MHD solar wind modeling with turbulence transport and eddy viscosity

    NASA Astrophysics Data System (ADS)

    Usmanov, A. V.; Goldstein, M. L.; Matthaeus, W. H.

    2014-12-01

    We present results from a three-fluid, fully three-dimensional MHD solar wind model that includes turbulence transport, eddy viscosity, turbulent resistivity, and turbulent heating. The solar wind plasma is described as a co-moving system of three species: the solar wind protons, electrons, and interstellar pickup protons. Separate energy equations are employed for each species. We obtain numerical solutions of Reynolds-averaged solar wind equations coupled with turbulence transport equations in the region from 0.3 to 100 AU. The integrated system of equations includes the effects of electron heat conduction, Coulomb collisions, photoionization of interstellar hydrogen atoms and their charge exchange with the solar wind protons, turbulence energy generation by pickup protons, and turbulent heating of solar wind protons and electrons. Using either a dipole approximation for the solar magnetic field or synoptic solar magnetograms from the Wilcox Solar Observatory for assigning boundary conditions at the coronal base, we apply the model to study the global structure of the solar wind and its three-dimensional properties, including turbulence parameters, throughout the heliosphere. The model results are compared with observations on WIND, Ulysses and Voyager 2 spacecraft. This work is partially supported by LWS and Heliophysics Grand Challenges programs.

  9. Fluoroquinolone-resistant extraintestinal pathogenic Escherichia coli, including O25b-ST131, isolated from faeces of hospitalized dogs in an Australian veterinary referral centre.

    PubMed

    Guo, Siyu; Brouwers, Huub J M; Cobbold, Rowland N; Platell, Joanne L; Chapman, Toni A; Barrs, Vanessa R; Johnson, James R; Trott, Darren J

    2013-05-01

    To determine rates of carriage of fluoroquinolone-resistant Escherichia coli and extraintestinal pathogenic E. coli (ExPEC) among dogs in a specialist referral hospital and to examine the population structure of the isolates. Fluoroquinolone-resistant faecal E. coli isolates (n = 232, from 23 of 123 dogs) recovered from hospitalized dogs in a veterinary referral centre in Sydney, Australia, over 140 days in 2009 were characterized by phylogenetic grouping, virulence genotyping and random amplified polymorphic DNA (RAPD) analysis. The RAPD dendrogram for representative isolates showed one group B2-associated cluster and three group D-associated clusters; each contained isolates with closely related ExPEC-associated virulence profiles. All group B2 faecal isolates represented the O25b-ST131 clonal group and were closely related to recent canine extraintestinal ST131 clinical isolates from the east coast of Australia by RAPD analysis. Hospitalized dogs may carry fluoroquinolone-resistant ExPEC in their faeces, including those representing O25b-ST131.

  10. Extraintestinal Pathogenic and Antimicrobial-Resistant Escherichia coli, Including Sequence Type 131 (ST131), from Retail Chicken Breasts in the United States in 2013.

    PubMed

    Johnson, James R; Porter, Stephen B; Johnston, Brian; Thuras, Paul; Clock, Sarah; Crupain, Michael; Rangan, Urvashi

    2017-03-15

    Chicken meat products are hypothesized to be vehicles for transmitting antimicrobial-resistant and extraintestinal pathogenic Escherichia coli (ExPEC) to consumers. To reassess this hypothesis in the current era of heightened concerns about antimicrobial use in food animals, we analyzed 175 chicken-source E. coli isolates from a 2013 Consumer Reports national survey. Isolates were screened by PCR for ExPEC-defining virulence genes. The 25 ExPEC isolates (12% of 175) and a 2:1 randomly selected set of 50 non-ExPEC isolates were assessed for their phylogenetic/clonal backgrounds and virulence genotypes for comparison with their resistance profiles and the claims on the retail packaging label ("organic," "no antibiotics," and "natural"). Compared with the findings for non-ExPEC isolates, the group of ExPEC isolates had a higher prevalence of phylogroup B2 isolates (44% versus 4%; P < 0.001) and a lower prevalence of phylogroup A isolates (4% versus 30%; P = 0.001), a higher prevalence of multiple individual virulence genes, higher virulence scores (median, 11 [range, 4 to 16] versus 8 [range, 1 to 14]; P = 0.001), and higher resistance scores (median, 4 [range, 0 to 8] versus 3 [range, 0 to 10]; P < 0.001). All five isolates of sequence type 131 (ST131) were ExPEC (P = 0.003), were as extensively resistant as the other isolates tested, and had higher virulence scores than the other isolates tested (median, 12 [range, 11 to 13] versus 8 [range, 1 to 16]; P = 0.005). Organic labeling predicted lower resistance scores (median, 2 [range, 0 to 3] versus 4 [range, 0 to 10]; P = 0.008) but no difference in ExPEC status or virulence scores. These findings document a persisting reservoir of extensively antimicrobial-resistant ExPEC isolates, including isolates from ST131, in retail chicken products in the United States, suggesting a potential public health threat.IMPORTANCE We found that among Escherichia coli isolates from retail chicken meat products purchased across the

  11. Self-consistent stationary MHD shear flows in the solar atmosphere as electric field generators

    NASA Astrophysics Data System (ADS)

    Nickeler, D. H.; Karlický, M.; Wiegelmann, T.; Kraus, M.

    2014-09-01

    Context. Magnetic fields and flows in coronal structures, for example, in gradual phases in flares, can be described by 2D and 3D magnetohydrostatic (MHS) and steady magnetohydrodynamic (MHD) equilibria. Aims: Within a physically simplified, but exact mathematical model, we study the electric currents and corresponding electric fields generated by shear flows. Methods: Starting from exact and analytically calculated magnetic potential fields, we solved the nonlinear MHD equations self-consistently. By applying a magnetic shear flow and assuming a nonideal MHD environment, we calculated an electric field via Faraday's law. The formal solution for the electromagnetic field allowed us to compute an expression of an effective resistivity similar to the collisionless Speiser resistivity. Results: We find that the electric field can be highly spatially structured, or in other words, filamented. The electric field component parallel to the magnetic field is the dominant component and is high where the resistivity has a maximum. The electric field is a potential field, therefore, the highest energy gain of the particles can be directly derived from the corresponding voltage. In our example of a coronal post-flare scenario we obtain electron energies of tens of keV, which are on the same order of magnitude as found observationally. This energy serves as a source for heating and acceleration of particles.

  12. Efficacy of a combined oral formulation of derquantel-abamectin against the adult and larval stages of nematodes in sheep, including anthelmintic-resistant strains.

    PubMed

    Little, Peter R; Hodge, Andrew; Maeder, Steven J; Wirtherle, Nicole C; Nicholas, David R; Cox, George G; Conder, George A

    2011-09-27

    Derquantel (DQL), a semi-synthetic member of a novel anthelmintic class, the spiroindoles, in combination with abamectin (ABA) [as the combination product STARTECT(®)] is a new entry for the treatment and control of parasites in sheep. The 19 studies reported herein were conducted in Australia, New Zealand, South Africa and the United Kingdom to demonstrate the efficacy of derquantel-abamectin (DQL-ABA) against a broad spectrum of gastrointestinal and respiratory nematodes of sheep, and to support registration of the combination product. Eleven studies were conducted using natural or experimental parasite infections with unknown or unconfirmed resistance, while eight studies utilised isolates/strains with confirmed or well characterised resistance to one or more currently available anthelmintics, including macrocyclic lactones. All studies included DQL-ABA and negative control groups, and in selected studies one or more reference anthelmintic groups were included. In all studies the commercial formulation of DQL-ABA was administered orally at 2mg/kg DQL and 0.2mg/kg ABA; placebo was administered in the same volume as DQL-ABA; and reference anthelmintics were administered as per label recommendations, except in one instance where levamisole was administered at twice the label dose. Infection, necropsy, worm collection and worm counting procedures were performed using standard techniques. Efficacy was calculated based on the percentage reduction in geometric mean worm count relative to negative control for each nematode species and lifecycle stage targeted. Twenty-two isolates/strains used in the eight studies targeting resistant worms had proven resistance: three to one anthelmintic class, eleven to two classes and eight to three or more classes; of these resistant strains, 16 demonstrated resistance to a macrocyclic lactone anthelmintic. Regardless of resistance status in the 19 studies, DQL-ABA controlled a broad range of economically important gastrointestinal

  13. Effects of centrifugal modification of magnetohydrodynamic equilibrium on resistive wall mode stability

    NASA Astrophysics Data System (ADS)

    Shiraishi, J.; Aiba, N.; Miyato, N.; Yagi, M.

    2014-08-01

    Toroidal rotation effects are self-consistently taken into account not only in the linear magnetohydrodynamic (MHD) stability analysis but also in the equilibrium calculation. The MHD equilibrium computation is affected by centrifugal force due to the toroidal rotation. To study the toroidal rotation effects on resistive wall modes (RWMs), a new code has been developed. The RWMaC modules, which solve the electromagnetic dynamics in vacuum and the resistive wall, have been implemented in the MINERVA code, which solves the Frieman-Rotenberg equation that describes the linear ideal MHD dynamics in a rotating plasma. It is shown that modification of MHD equilibrium by the centrifugal force significantly reduces growth rates of RWMs with fast rotation in the order of M2 = 0.1 where M is the Mach number. Moreover, it can open a stable window which does not exist under the assumption that the rotation affects only the linear dynamics. The rotation modifies the equilibrium pressure gradient and current density profiles, which results in the change of potential energy including rotational effects.

  14. Decreasing population selection rates of resistance mutation K65R over time in HIV-1 patients receiving combination therapy including tenofovir

    PubMed Central

    Theys, K.; Snoeck, J.; Vercauteren, J.; Abecasis, A. B.; Vandamme, A.-M.; Camacho, R. J.

    2013-01-01

    Objectives The use of tenofovir is highly associated with the emergence of mutation K65R, which confers broad resistance to nucleoside/nucleotide analogue reverse transcriptase inhibitors (NRTIs), especially when tenofovir is combined with other NRTIs also selecting for K65R. Although recent HIV-1 treatment guidelines discouraging these combinations resulted in reduced K65R selection with tenofovir, updated information on the impact of currently recommended regimens on the population selection rate of K65R is presently lacking. Methods In this study, we evaluated changes over time in the selection rate of resistance mutation K65R in a large population of 2736 HIV-1-infected patients failing combination antiretroviral treatment between 2002 and 2010. Results The K65R resistance mutation was detected in 144 patients, a prevalence of 5.3%. A large majority of observed K65R cases were explained by the use of tenofovir, reflecting its wide use in clinical practice. However, changing patterns over time in NRTIs accompanying tenofovir resulted in a persistent decreasing probability of K65R selection by tenofovir-based therapy. The currently recommended NRTI combination tenofovir/emtricitabine was associated with a low probability of K65R emergence. For any given dual NRTI combination including tenofovir, higher selection rates of K65R were consistently observed with a non-nucleoside reverse transcriptase inhibitor than with a protease inhibitor as the third agent. Discussion Our finding of a stable time trend of K65R despite elevated use of tenofovir illustrates increased potency of current HIV-1 therapy including tenofovir. PMID:23027713

  15. Energy storage and dissipation in the magnetotail during substorms. 2. MHD simulations

    SciTech Connect

    Steinolfson, R.S. ); Winglee, R.M. )

    1993-05-01

    The authors present a global MHD simulation of the magnetotail in an effort to study magnetic storm development. They address the question of energy storage in the current sheet in the early phases of storm growth, which previous simulations have not shown. They address this problem by dealing with the variation of the resistivity throughout the magnetosphere. They argue that MHD theory should provide a suitable representation to this problem on a global scale, even if it does not handle all details adequately. For their simulation they use three different forms for the resistivity. First is a uniform and constant resistivity. Second is a resistivity proportional to the current density, which is related to argument that resistivity is driven by wave-particle interactions which should be strongest in regions where the current is the greatest. Thirdly is a model where the resistivity varies with the magnetic field strength, which was suggested by previous results from particle simulations of the same problem. The simulation then gives approximately the same response of the magnetosphere for all three of the models. Each results in the formation and ejection of plasmoids, but the energy stored in the magnetotail, the timing of substorm onset in relation to the appearance of a southward interplanetary magnetic field, and the speed of ejection of the plasmoids formed differ with the resistivity models.

  16. MHD simulations of magnetized laser-plasma interaction for laboratory astrophysics

    NASA Astrophysics Data System (ADS)

    Khiar, Benjamin; Ciardi, Andrea; Vinci, Tommaso; Revet, Guilhem; Fuchs, Julien; Higginson, Drew

    2015-11-01

    Laser-driven plasmas coupled with externally applied strong, steady-state, magnetic fields have applications that range from ICF to astrophysical studies of jet collimation, accretion shock dynamics in young stars and streaming instabilities in space plasmas. We have recently included the modelling of laser energy deposition in our three-dimensional, resistive two-temperature MHD code GORGON. The model assumes linear inverse-bremsstrahlung absorption and the laser propagation is done in the geometrical optics approximation. We present full scale numerical simulations of actual experiments performed on the ELFIE installation at LULI, including plasma generated from single and multiple laser plasmas embedded in a magnetic field of strength up to 20 T, and experiments and astrophysical simulations that have shown the viability of poloidal magnetic fields to directly result in the collimation of outflows and the formation of jets in astrophysical accreting systems, such as in young stellar objects. The authors acknowledge the support from the Ile-de-France DIM ACAV, from the LABEX Plas@par and from the ANR grant SILAMPA.

  17. MHD air heater development technology. Technical progress report, April 1, 1980-June 30, 1980

    SciTech Connect

    1980-07-01

    Technology development for the directly-fired high temperature air heater (HTAH) for MHD power plants is described. Work is being done under three tasks as described in the following. (1) materials selection, evaluation, and development: The objective of this task is to continue development of ceramic materials technology for the directly-fired HTAH. The scope of the work will include compilation of materials data, materials selection for testing and design studies, materials property determination, liaison with refractory manufacturers and other organizations to encourage development of materials and fabrication technology, establishment of preliminary HTAH material specifications, analyses of test materials, and development of criteria for thermal stress limits for crack-tolerant refractory materials. (2) operability, performance, and materials testing: The objectives of this task are to demonstrate the technical feasibility of operating a directly-fired HTAH (including both the heater matrix and valves), to continue obtaining information on life and corrosion resistance of HTAH materials, and to obtain design information for full-scale studies and future design work. (3) full-scale design concepts: The objectives of this task are to begin the identification of HTAH control requirements and control system needs, and to continue full-scale study efforts incorporating updated materials and design information in order to identify development needs for the HTAH development program. Progress is described. (WHK)

  18. Suspected nosocomial infections with multi-drug resistant E. coli, including extended-spectrum beta-lactamase (ESBL)-producing strains, in an equine clinic.

    PubMed

    Walther, Birgit; Lübke-Becker, Antina; Stamm, Ivonne; Gehlen, Heidrun; Barton, Ann Kristin; Janssen, Traute; Wieler, Lothar H; Guenther, Sebastian

    2014-01-01

    Enterobacteriaceae such as Escherichia coli are common commensals as well as opportunistic and obligate pathogens. They cause a broad spectrum of infectious diseases in various hosts, including hospital-associated infections. In recent years, the rise of extended spectrum beta-lactamase (ESBL)-producing E. coli in companion animals (dogs, cats and horses) has been striking. However, reports on nosocomial infections are mostly anecdotic. Here we report on the suspected nosocomial spread of both ESBL-producing and non-ESBL-producing multi-drug resistant E. coli isolates in three equine patients within an equine clinic. Unlike easy-to-clean hospitalization opportunities available for small animal settings like boxes and cages made of ceramic floor tiles or stainless steel, clinical settings for horses are challenging environments for infection control programs due to unavoidable extraneous material including at least hay and materials used for horse bedding. The development of practice-orientated recommendations is needed to improve the possibilities for infection control to prevent nosocomial infections with multi-drug resistant and other transmissible pathogens in equine clinical settings.

  19. The Ellis Island Effect: A novel mobile element in a multi-drug resistant Bacteroides fragilis clinical isolate includes a mosaic of resistance genes from Gram-positive bacteria.

    PubMed

    Husain, Fasahath; Veeranagouda, Yaligara; Boente, Renata; Tang, Kevin; Mulato, Gabriela; Wexler, Hannah M

    2014-01-01

    Objectives: Bacteroides fragilis, a Gram-negative anaerobic bacterium, is alternately a gut commensal or virulent pathogen and is an important reservoir for horizontal gene transfer (HGT) of bacterial resistance and virulence genes in the human gastrointestinal tract. We identified a unique conjugative transposon (CTn) in a multidrug resistant clinical isolate of B. fragilis (BF-HMW615); we named this element CTnHyb because it included a hybrid mosaic of foreign elements. This study reports the characterization of CTnHyb and discusses the potential impact on horizontal spread of resistance genes. Results: CTnHyb contains several efflux pump genes and several genes that confer or may confer antibiotic resistance to tetracycline, kanamycin, metronidazole and spectinomycin (truncated gene). CTnHyb also contains a mosaic of mobile elements from Gram-positive organisms. CTnHyb is easily transferred from BF-HMW615 (the original isolate) to BF638R (lab strain) and integrated into the BF638R chromosome. The "foreign" (from Gram-positive bacteria) nucleotide sequences within CTnHyb were > 99% preserved indicating that the gene acquisition from the Gram-positive bacteria was very recent. Conclusion: CTnHyb is a novel CTn residing in a multidrug resistant strain of B. fragilis. The global nature and wide phylogenetic reach of HGT means that any gene in any bacterium can potentially be mobilized. Understanding the mechanisms that drive the formation and transfer of these elements and, potentially, ways to limit the transfer are necessary to prevent a devastating spread of resistance elements.

  20. MHD shocks in coronal mass ejections

    NASA Technical Reports Server (NTRS)

    Steinolfson, R. S.

    1991-01-01

    The primary objective of this research program is the study of the magnetohydrodynamic (MHD) shocks and nonlinear simple waves produced as a result of the interaction of ejected lower coronal plasma with the ambient corona. The types of shocks and nonlinear simple waves produced for representative coronal conditions and disturbance velocities were determined. The wave system and the interactions between the ejecta and ambient corona were studied using both analytic theory and numerical solutions of the time-dependent, nonlinear MHD equations. Observations from the SMM coronagraph/polarimeter provided both guidance and motivation and are used extensively in evaluating the results. As a natural consequence of the comparisons with the data, the simulations assisted in better understanding the physical interactions in coronal mass ejections (CME's).

  1. Numerical MHD codes for modeling astrophysical flows

    NASA Astrophysics Data System (ADS)

    Koldoba, A. V.; Ustyugova, G. V.; Lii, P. S.; Comins, M. L.; Dyda, S.; Romanova, M. M.; Lovelace, R. V. E.

    2016-05-01

    We describe a Godunov-type magnetohydrodynamic (MHD) code based on the Miyoshi and Kusano (2005) solver which can be used to solve various astrophysical hydrodynamic and MHD problems. The energy equation is in the form of entropy conservation. The code has been implemented on several different coordinate systems: 2.5D axisymmetric cylindrical coordinates, 2D Cartesian coordinates, 2D plane polar coordinates, and fully 3D cylindrical coordinates. Viscosity and diffusivity are implemented in the code to control the accretion rate in the disk and the rate of penetration of the disk matter through the magnetic field lines. The code has been utilized for the numerical investigations of a number of different astrophysical problems, several examples of which are shown.

  2. Coherent Eigenmodes in Homogeneous MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.

    2010-01-01

    The statistical mechanics of Fourier models of ideal, homogeneous, incompressible magnetohydrodynamic (MHD) turbulence is discussed, along with their relevance for dissipative magnetofluids. Although statistical theory predicts that Fourier coefficients of fluid velocity and magnetic field are zero-mean random variables, numerical simulations clearly show that certain coefficients have a non-zero mean value that can be very large compared to the associated standard deviation, i.e., we have coherent structure. We use eigenanalysis of the modal covariance matrices in the probability density function to explain this phenomena in terms of `broken ergodicity', which is defined to occur when dynamical behavior does not match ensemble predictions on very long time-scales. We provide examples from 2-D and 3-D magnetohydrodynamic simulations of homogeneous turbulence, and show new results from long-time simulations of MHD turbulence with and without a mean magnetic field

  3. Amplitudes of MHD Waves in Sunspots

    NASA Astrophysics Data System (ADS)

    Norton, Aimee Ann; Cally, Paul; Baldner, Charles; Kleint, Lucia; Tarbell, Theodore D.; De Pontieu, Bart; Scherrer, Philip H.; Rajaguru, Paul

    2016-05-01

    The conversion of p-modes into MHD waves by strong magnetic fields occurs mainly in the sub-photospheric layers. The photospheric signatures of MHD waves are weak due to low amplitudes at the beta=1 equipartion level where mode-conversion occurs. We report on small amplitude oscillations observed in the photosphere with Hinode SOT/SP in which we analyze time series for sunspots ARs 12186 (11.10.2014) and 12434 (17.10.2015). No significant magnetic field oscillations are recovered in the umbra or penumbra in the ME inversion. However, periodicities in the inclination angle are found at the umbral/penumbral boundary with 5 minute periods. Upward propagating waves are indicated in the intensity signals correlated between HMI and AIA at different heights. We compare SP results with the oscillations observed in HMI data. Simultaneous IRIS data shows transition region brightening above the umbral core.

  4. MHD processes in the outer heliosphere

    NASA Technical Reports Server (NTRS)

    Burlaga, L. F.

    1984-01-01

    The magnetic field measurements from Voyager and the magnetohydrodynamic (MHD) processes in the outer heliosphere are reviewed. A bibliography of the experimental and theoretical work concerning magnetic fields and plasmas observed in the outer heliosphere is given. Emphasis in this review is on basic concepts and dynamical processes involving the magnetic field. The theory that serves to explain and unify the interplanetary magnetic field and plasma observations is magnetohydrodynamics. Basic physical processes and observations that relate directly to solutions of the MHD equations are emphasized, but obtaining solutions of this complex system of equations involves various assumptions and approximations. The spatial and temporal complexity of the outer heliosphere and some approaches for dealing with this complexity are discussed.

  5. Analytical investigation of critical MHD phenomena

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Development and analysis of schemes for suppression of the startup overvoltage transient in the AEDC High Performance Demonstration Experiment (HPDE), analysis of performance enhancement due to electrode voltage drop reduction by use of pyrolytic graphites in the HPDE, prediction of optimal loading schemes for the HPDE, prediction of PHDE performance with a diagonal electrical connection, and predictions of the likelihood and effects of axial current leakage between adjacent electrodes in the HPDE are reviewed. Simulations of tests at the AEDC/HPDE with STD Research Corporation multidimensional and time dependent computer codes provided additional validation for the computer codes and shed light on physical mechanisms which govern performance and durability of MHD power generators. The magnetoaerothermal effect was predicted by STD Research Corporation to have a significant effect on the HPDE/MHD generator performance at high interaction.

  6. Activity of Debio1452, a FabI Inhibitor with Potent Activity against Staphylococcus aureus and Coagulase-Negative Staphylococcus spp., Including Multidrug-Resistant Strains

    PubMed Central

    Rhomberg, Paul R.; Kaplan, Nachum; Jones, Ronald N.; Farrell, David J.

    2015-01-01

    Staphylococcus aureus and coagulase-negative staphylococci (CoNS) are responsible for a wide variety of human infections. The investigational antibacterial Debio1450 (previously AFN-1720), a prodrug of Debio1452 (previously AFN-1252), specifically targets staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 inhibits FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. The activity of Debio1452 against CoNS, methicillin-susceptible S. aureus (MSSA), and methicillin-resistant S. aureus (MRSA), including significant clones, was determined. A globally diverse collection of 574 patient isolates from 35 countries was tested that included CoNS (6 species, 103 strains), MSSA (154 strains), MRSA (163 strains), and molecularly characterized strains (including spa-typed MRSA clones; 154 strains). The isolates were tested for susceptibility by CLSI broth microdilution methods against Debio1452 and 10 comparators. The susceptibility rates for the comparators were determined using CLSI and EUCAST breakpoint criteria. All S. aureus and CoNS strains were inhibited by Debio1452 concentrations of ≤0.12 and ≤0.5 μg/ml, respectively. The MIC50s for MSSA, MRSA, and molecularly characterized MRSA strains were 0.004 μg/ml, and the MIC90s ranged from 0.008 to 0.03 μg/ml. The MICs were higher for the CoNS isolates (MIC50/90, 0.015/0.12 μg/ml). Among S. aureus strains, resistance was common for erythromycin (61.6%), levofloxacin (49.0%), clindamycin (27.6%), tetracycline (15.7%), and trimethoprim-sulfamethoxazole (7.0%). Debio1452 demonstrated potent activity against MSSA, MRSA, and CoNS. Debio1452 showed significantly greater activity overall (MIC50, 0.004 μg/ml) than the other agents tested against these staphylococcal species, which included dominant MRSA clones and strains resistant to currently utilized antimicrobial agents. PMID:25691627

  7. Design Study: Rocket Based MHD Generator

    NASA Technical Reports Server (NTRS)

    1997-01-01

    This report addresses the technical feasibility and design of a rocket based MHD generator using a sub-scale LOx/RP rocket motor. The design study was constrained by assuming the generator must function within the performance and structural limits of an existing magnet and by assuming realistic limits on (1) the axial electric field, (2) the Hall parameter, (3) current density, and (4) heat flux (given the criteria of heat sink operation). The major results of the work are summarized as follows: (1) A Faraday type of generator with rectangular cross section is designed to operate with a combustor pressure of 300 psi. Based on a magnetic field strength of 1.5 Tesla, the electrical power output from this generator is estimated to be 54.2 KW with potassium seed (weight fraction 3.74%) and 92 KW with cesium seed (weight fraction 9.66%). The former corresponds to a enthalpy extraction ratio of 2.36% while that for the latter is 4.16%; (2) A conceptual design of the Faraday MHD channel is proposed, based on a maximum operating time of 10 to 15 seconds. This concept utilizes a phenolic back wall for inserting the electrodes and inter-electrode insulators. Copper electrode and aluminum oxide insulator are suggested for this channel; and (3) A testing configuration for the sub-scale rocket based MHD system is proposed. An estimate of performance of an ideal rocket based MHD accelerator is performed. With a current density constraint of 5 Amps/cm(exp 2) and a conductivity of 30 Siemens/m, the push power density can be 250, 431, and 750 MW/m(sup 3) when the induced voltage uB have values of 5, 10, and 15 KV/m, respectively.

  8. Polydispersed MHD flow in a cylindrical vessel

    SciTech Connect

    Gorislavets, Yu.M.

    1986-07-01

    A large number of works on MHD separation of nonelectrically conducting particles assume that particle growth does not occur. The authors adopt the well-known model of coagulation according to which the collision of particles is determined only by their mutual displacement in the carrying liquid. Figures show relative density of coagulating particles, and particle-size distribution. It was shown that the process of coagulation in the situation under study develops in an avalanchelike fashion.

  9. Laboratory-produced MHD plasma jets

    NASA Astrophysics Data System (ADS)

    Bellan, Paul

    2008-04-01

    Because space plasmas are neither confined by vacuum chamber walls nor have magnetic fields produced by physical coils, space plasmas have shapes that are much less determinate than lab plasmas. An experimental program underway at Caltech produces plasmas where the shape is neither fixed by a vacuum chamber wall nor imposed by an external coil set, but rather is allowed to be determined by self-organizing MHD processes subject to the constraint of imposed boundary conditions analogous to the boundary conditions of space plasmas. These self-organizing processes are believed to be fundamental to astrophysical jets, solar coronal loops, and MHD turbulence (e.g. Taylor relaxation). The experimental dynamics are sufficiently reproducible to allow detailed study despite the morphology being complex and dynamic. A surprising result has been the observation that instead of the plasma uniformly filling up the available volume, the plasma is spatially localized in a highly collimated, small diameter magnetic flux tube, the length and axis of which change in time in response to MHD forces. A model shows that the collimation results from stagnation of linked magnetic flux frozen into a MHD-driven jet that accelerates plasma from the wall into the flux tube, filling the flux tube with plasma. Jet flow has been imaged with a high-speed multi-frame camera, diagnosed via Doppler spectroscopy, and most recently (i) the collision between two opposing, color-coded jets flowing from opposite ends of a flux tube has been observed, and (ii) the collision of a jet with a target cloud has been observed.

  10. MHD simulations on an unstructured mesh

    SciTech Connect

    Strauss, H.R.; Park, W.; Belova, E.; Fu, G.Y.; Longcope, D.W.; Sugiyama, L.E.

    1998-12-31

    Two reasons for using an unstructured computational mesh are adaptivity, and alignment with arbitrarily shaped boundaries. Two codes which use finite element discretization on an unstructured mesh are described. FEM3D solves 2D and 3D RMHD using an adaptive grid. MH3D++, which incorporates methods of FEM3D into the MH3D generalized MHD code, can be used with shaped boundaries, which might be 3D.

  11. Statistical Theory of the Ideal MHD Geodynamo

    NASA Technical Reports Server (NTRS)

    Shebalin, J. V.

    2012-01-01

    A statistical theory of geodynamo action is developed, using a mathematical model of the geodynamo as a rotating outer core containing an ideal (i.e., no dissipation), incompressible, turbulent, convecting magnetofluid. On the concentric inner and outer spherical bounding surfaces the normal components of the velocity, magnetic field, vorticity and electric current are zero, as is the temperature fluctuation. This allows the use of a set of Galerkin expansion functions that are common to both velocity and magnetic field, as well as vorticity, current and the temperature fluctuation. The resulting dynamical system, based on the Boussinesq form of the magnetohydrodynamic (MHD) equations, represents MHD turbulence in a spherical domain. These basic equations (minus the temperature equation) and boundary conditions have been used previously in numerical simulations of forced, decaying MHD turbulence inside a sphere [1,2]. Here, the ideal case is studied through statistical analysis and leads to a prediction that an ideal coherent structure will be found in the form of a large-scale quasistationary magnetic field that results from broken ergodicity, an effect that has been previously studied both analytically and numerically for homogeneous MHD turbulence [3,4]. The axial dipole component becomes prominent when there is a relatively large magnetic helicity (proportional to the global correlation of magnetic vector potential and magnetic field) and a stationary, nonzero cross helicity (proportional to the global correlation of velocity and magnetic field). The expected angle of the dipole moment vector with respect to the rotation axis is found to decrease to a minimum as the average cross helicity increases for a fixed value of magnetic helicity and then to increase again when average cross helicity approaches its maximum possible value. Only a relatively small value of cross helicity is needed to produce a dipole moment vector that is aligned at approx.10deg with the

  12. Extended MHD modeling of tearing-driven magnetic relaxation

    NASA Astrophysics Data System (ADS)

    Sauppe, J. P.; Sovinec, C. R.

    2017-05-01

    Discrete relaxation events in reversed-field pinch relevant configurations are investigated numerically with nonlinear extended magnetohydrodynamic (MHD) modeling, including the Hall term in Ohm's law and first-order ion finite Larmor radius effects. Results show variability among relaxation events, where the Hall dynamo effect may help or impede the MHD dynamo effect in relaxing the parallel current density profile. The competitive behavior arises from multi-helicity conditions where the dominant magnetic fluctuation is relatively small. The resulting changes in parallel current density and parallel flow are aligned in the core, consistent with experimental observations. The analysis of simulation results also confirms that the force density from fluctuation-induced Reynolds stress arises subsequent to the drive from the fluctuation-induced Lorentz force density. Transport of the momentum density is found to be dominated by the fluctuation-induced Maxwell stress over most of the cross section with viscous and gyroviscous contributions being large in the edge region. The findings resolve a discrepancy with respect to the relative orientation of current density and flow relaxation, which had not been realized or investigated in King et al. [Phys. Plasmas 19, 055905 (2012)], where only the magnitude of flow relaxation is actually consistent with experimental results.

  13. Final Report: "Large-Eddy Simulation of Anisotropic MHD Turbulence"

    SciTech Connect

    Zikanov, Oleg

    2008-06-23

    To acquire better understanding of turbulence in flows of liquid metals and other electrically conducting fluids in the presence of steady magnetic fields and to develop an accurate and physically adequate LES (large-eddy simulation) model for such flows. The scientific objectives formulated in the project proposal have been fully completed. Several new directions were initiated and advanced in the course of work. Particular achievements include a detailed study of transformation of turbulence caused by the imposed magnetic field, development of an LES model that accurately reproduces this transformation, and solution of several fundamental questions of the interaction between the magnetic field and fluid flows. Eight papers have been published in respected peer-reviewed journals, with two more papers currently undergoing review, and one in preparation for submission. A post-doctoral researcher and a graduate student have been trained in the areas of MHD, turbulence research, and computational methods. Close collaboration ties have been established with the MHD research centers in Germany and Belgium.

  14. Inductive-dynamic magnetosphere-ionosphere coupling via MHD waves

    NASA Astrophysics Data System (ADS)

    Tu, Jiannan; Song, Paul; Vasyliūnas, Vytenis M.

    2014-01-01

    In the present study, we investigate magnetosphere-ionosphere/thermosphere (M-IT) coupling via MHD waves by numerically solving time-dependent continuity, momentum, and energy equations for ions and neutrals, together with Maxwell's equations (Ampère's and Faraday's laws) and with photochemistry included. This inductive-dynamic approach we use is fundamentally different from those in previous magnetosphere-ionosphere (M-I) coupling models: all MHD wave modes are retained, and energy and momentum exchange between waves and plasma are incorporated into the governing equations, allowing a self-consistent examination of dynamic M-I coupling. Simulations, using an implicit numerical scheme, of the 1-D ionosphere/thermosphere system responding to an imposed convection velocity at the top boundary are presented to show how magnetosphere and ionosphere are coupled through Alfvén waves during the transient stage when the IT system changes from one quasi steady state to another. Wave reflection from the low-altitude ionosphere plays an essential role, causing overshoots and oscillations of ionospheric perturbations, and the dynamical Hall effect is an inherent aspect of the M-I coupling. The simulations demonstrate that the ionosphere/thermosphere responds to magnetospheric driving forces as a damped oscillator.

  15. MHD (magnetohydrodynamic) undersea propulsion: A novel concept with renewed interest

    SciTech Connect

    Doss, E.D.; Geyer, H.K. ); Roy, G.D. )

    1990-01-01

    This paper discusses the reasons for the national and international renewed interest in the concept of MHD seawater propulsion. The main advantages of this concept are presented, together with some of the technical challenges that need to be overcome to achieve reliability, performance, and stealth. The paper discusses in more detail some of the technical issues and loss mechanisms influencing the thruster performance in terms of its electrical efficiency. Among the issues discussed are the jet losses and nozzle efficiency. Ohmic losses and frictional losses inside the thruster. Also discussed are the electrical end losses caused by the fringing magnetic field near the end of the electrodes. It has been shown that the frictional and end losses can have strong adverse effects on the thruster performance. Furthermore, a parametric study has been performed to investigate the effects of several parameters on the performance of the MHD thrusters. Those parameters include the magnetic field, thruster diameter, all roughness, flow velocity, and electrical load factor. The results of the parametric study indicate that the thruster efficiency increases with the strength of the magnetic field and thruster diameter, and decreases with the wall roughness and the flow velocity. 8 refs., 8 figs.

  16. An Unsplit, Cell-Centered Godunov Method for Ideal MHD

    SciTech Connect

    Fisher, R; Crockett, R; Colella, P; Klein, R; McKee, C

    2003-10-16

    We present a second-order Godunov algorithm for multidimensional, ideal MHD. Our algorithm is based on the unsplit formulation of Colella, with all of the primary dependent variables centered at the same location. To properly represent the divergence-free condition of the magnetic fields, we apply a discrete projection to the intermediate values of the field at cell faces, and apply a filter to the primary dependent variables at the end of each time step. We apply the method to a suite of linear and nonlinear tests to ascertain accuracy and stability of the scheme under a variety of conditions. The test suite includes rotated planar linear waves, MHD shock tube problems, and low-beta flux tubes. For all of these cases, we observe that the algorithm is second-order accurate for smooth solutions, converges to the correct weak solution for problems involving shocks, and exhibits no evidence of instability or loss of accuracy due to the possible presence of non-solenoidal fields.

  17. An unsplit, cell-centered Godunov method for ideal MHD

    SciTech Connect

    Crockett, Robert K.; Colella, Phillip; Fisher, Robert T.; Klein, Richard I.; McKee, Christopher F.

    2003-08-29

    We present a second-order Godunov algorithm for multidimensional, ideal MHD. Our algorithm is based on the unsplit formulation of Colella (J. Comput. Phys. vol. 87, 1990), with all of the primary dependent variables centered at the same location. To properly represent the divergence-free condition of the magnetic fields, we apply a discrete projection to the intermediate values of the field at cell faces, and apply a filter to the primary dependent variables at the end of each time step. We test the method against a suite of linear and nonlinear tests to ascertain accuracy and stability of the scheme under a variety of conditions. The test suite includes rotated planar linear waves, MHD shock tube problems, low-beta flux tubes, and a magnetized rotor problem. For all of these cases, we observe that the algorithm is second-order accurate for smooth solutions, converges to the correct weak solution for problems involving shocks, and exhibits no evidence of instability or loss of accuracy due to the possible presence of non-solenoidal fields.

  18. Capabilities of Fully Parallelized MHD Stability Code MARS

    NASA Astrophysics Data System (ADS)

    Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang

    2016-10-01

    Results of full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. Parallel version of MARS, named PMARS, has been recently developed at FAR-TECH. Parallelized MARS is an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, implemented in MARS. Parallelization of the code included parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse vector iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the MARS algorithm using parallel libraries and procedures. Parallelized MARS is capable of calculating eigenmodes with significantly increased spatial resolution: up to 5,000 adapted radial grid points with up to 500 poloidal harmonics. Such resolution is sufficient for simulation of kink, tearing and peeling-ballooning instabilities with physically relevant parameters. Work is supported by the U.S. DOE SBIR program.

  19. MHD Turbulence in the Taurus Molecular Cloud

    NASA Astrophysics Data System (ADS)

    Heyer, M.; Gong, H.; Brunt, C.; Ostriker, E.

    2005-12-01

    The presence of MHD turbulence in the Taurus Molecular Cloud is examined from 12CO and 13CO J=1-0 imaging observations using the FCRAO 14 meter telescope. The degree of velocity anisotropy is measured from velocity structure functions derived separately along the x and y axes using Principal Component Analysis of spectroscopic imaging data (Brunt & Heyer 2002). Such anisotropy is predicted from model descriptions and computational simulations of MHD turbulence in the case of strong magnetic fields (Goldreich & Sridhar 1995; Cho, Lazarian, & Vishniac 2002; Vestuto, Ostriker, & Stone 2003). Within a subfield of the Taurus image where the column densities are low, this velocity anisotropy is largest along an angle that is coincident with the local magnetic field direction determined independently from optical polarization of background stars.The structure function derived from data perpendicular to the local field shows a shallower scaling exponent and a larger scaling coefficient than the values that describe the structure function constructed along the magnetic field as predicted by the MHD models. This alignment provides strong evidence that the magnetic field is a significant dynamical force within this column density regime of the Taurus cloud.

  20. NASA Lewis Research Center combustion MHD experiment

    NASA Astrophysics Data System (ADS)

    Smith, J. M.

    The MHD power generation experiments were conducted in a high field strength cryomagnet which was adapted from an existing facility. In its original construction, it consisted of 12 high purity aluminum coils pool cooled in a bath of liquid neon. In this configuration, a peak field of 15 tesla was produced. For the present experiments, the center four coils were removed and a 23 cm diameter transverse warm bore tube was inserted to allow the placement of the MHD experiment between the remaining eight coils. In this configuration, a peak field of 6 tesla should be obtainable. The time duration of the experiment is limited by the neon supply which allows on the order of 1 minute of total operating time followed by an 18-hour reliquefaction period. As a result, the experiments are run in a pulsed mode. The run duration for the data presented here was 5 sec. The magnetic field profile along the MHD duct is shown. Since the working fluid is in essence superheated steam, it is easily water quenched at the exit of the diffuser and the components are designed vacuum tight so that the exhaust pipe and demister an be pumped down to simulate the vacuum of outer space.

  1. Modeling open boundaries in dissipative MHD simulation

    NASA Astrophysics Data System (ADS)

    Meier, E. T.; Glasser, A. H.; Lukin, V. S.; Shumlak, U.

    2012-04-01

    The truncation of large physical domains to concentrate computational resources is necessary or desirable in simulating many natural and man-made plasma phenomena. Three open boundary condition (BC) methods for such domain truncation of dissipative magnetohydrodynamics (MHD) problems are described and compared here. A novel technique, lacuna-based open boundary conditions (LOBC), is presented for applying open BC to dissipative MHD and other hyperbolic and mixed hyperbolic-parabolic systems of partial differential equations. LOBC, based on manipulating Calderon-type near-boundary sources, essentially damp hyperbolic effects in an exterior region attached to the simulation domain and apply BC appropriate for the remaining parabolic effects (if present) at the exterior region boundary. Another technique, approximate Riemann BC (ARBC), is adapted from finite volume and discontinuous Galerkin methods. In ARBC, the value of incoming flux is specified using a local, characteristic-based method. A third commonly-used open BC, zero-normal derivative BC (ZND BC), is presented for comparison. These open BC are tested in several gas dynamics and dissipative MHD problems. LOBC are found to give stable, low-reflection solutions even in the presence of strong parabolic behavior, while ARBC are stable only when hyperbolic behavior is dominant. Pros and cons of the techniques are discussed and put into context within the body of open BC research to date.

  2. The Statistical Mechanics of Ideal MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.

    2003-01-01

    Turbulence is a universal, nonlinear phenomenon found in all energetic fluid and plasma motion. In particular. understanding magneto hydrodynamic (MHD) turbulence and incorporating its effects in the computation and prediction of the flow of ionized gases in space, for example, are great challenges that must be met if such computations and predictions are to be meaningful. Although a general solution to the "problem of turbulence" does not exist in closed form, numerical integrations allow us to explore the phase space of solutions for both ideal and dissipative flows. For homogeneous, incompressible turbulence, Fourier methods are appropriate, and phase space is defined by the Fourier coefficients of the physical fields. In the case of ideal MHD flows, a fairly robust statistical mechanics has been developed, in which the symmetry and ergodic properties of phase space is understood. A discussion of these properties will illuminate our principal discovery: Coherent structure and randomness co-exist in ideal MHD turbulence. For dissipative flows, as opposed to ideal flows, progress beyond the dimensional analysis of Kolmogorov has been difficult. Here, some possible future directions that draw on the ideal results will also be discussed. Our conclusion will be that while ideal turbulence is now well understood, real turbulence still presents great challenges.

  3. Shock Waves in Hall-MHD

    NASA Astrophysics Data System (ADS)

    Hagstrom, George; Hameiri, Eliezer

    2012-03-01

    Hall-MHD is a partial differential equation of degenerate parabolic type that describes the dynamics of an ideal two fluid plasma with massless electrons. We study shock waves and discontinuities in this system. We characterize planar travelling wave solutions and find solutions with discontinuities in the hydrodynamic variables. These solutions, which correspond to the ion-acoustic wave, arise due to the presence of hydrodynamic real characteristics in Hall-MHD. We demonstrate finite-time discontinuity formation for certain types of initial data with discontinuous derivatives and study the shock structure under different regularizations. We also explore the possible existence of solutions with discontinuous magnetic field. A non-algebraic, non-local set of jump conditions is derived under the assumption of [B]!=0. These conditions are used to study the contact discontinuity and it is shown that massless electrons crossing the surface of discontinuity may enter and leave at different locations. These conditions suggest the possible existence of mathematically novel shocks in Hall-MHD.

  4. Robust preconditioners for incompressible MHD models

    NASA Astrophysics Data System (ADS)

    Ma, Yicong; Hu, Kaibo; Hu, Xiaozhe; Xu, Jinchao

    2016-07-01

    In this paper, we develop two classes of robust preconditioners for the structure-preserving discretization of the incompressible magnetohydrodynamics (MHD) system. By studying the well-posedness of the discrete system, we design block preconditioners for them and carry out rigorous analysis on their performance. We prove that such preconditioners are robust with respect to most physical and discretization parameters. In our proof, we improve the existing estimates of the block triangular preconditioners for saddle point problems by removing the scaling parameters, which are usually difficult to choose in practice. This new technique is applicable not only to the MHD system, but also to other problems. Moreover, we prove that Krylov iterative methods with our preconditioners preserve the divergence-free condition exactly, which complements the structure-preserving discretization. Another feature is that we can directly generalize this technique to other discretizations of the MHD system. We also present preliminary numerical results to support the theoretical results and demonstrate the robustness of the proposed preconditioners.

  5. Inductive ionospheric solver for magnetospheric MHD simulations

    NASA Astrophysics Data System (ADS)

    Vanhamäki, H.

    2011-01-01

    We present a new scheme for solving the ionospheric boundary conditions required in magnetospheric MHD simulations. In contrast to the electrostatic ionospheric solvers currently in use, the new solver takes ionospheric induction into account by solving Faraday's law simultaneously with Ohm's law and current continuity. From the viewpoint of an MHD simulation, the new inductive solver is similar to the electrostatic solvers, as the same input data is used (field-aligned current [FAC] and ionospheric conductances) and similar output is produced (ionospheric electric field). The inductive solver is tested using realistic, databased models of an omega-band and westward traveling surge. Although the tests were performed with local models and MHD simulations require a global ionospheric solution, we may nevertheless conclude that the new solution scheme is feasible also in practice. In the test cases the difference between static and electrodynamic solutions is up to ~10 V km-1 in certain locations, or up to 20-40% of the total electric field. This is in agreement with previous estimates. It should also be noted that if FAC is replaced by the ground magnetic field (or ionospheric equivalent current) in the input data set, exactly the same formalism can be used to construct an inductive version of the KRM method originally developed by Kamide et al. (1981).

  6. Building Action Principles for Extended MHD Models

    NASA Astrophysics Data System (ADS)

    Keramidas Charidakos, Ioannis; Lingam, Manasvi; Morrison, Philip; White, Ryan; Wurm, Alexander

    2014-10-01

    The general, non-dissipative, two-fluid model in plasma physics is Hamiltonian, but this property is sometimes lost in the process of deriving simplified two-fluid or one-fluid models from the two-fluid equations of motion. One way to ensure that the reduced models are Hamiltonian is to derive them from an action. We start with the general two-fluid action functional for an electron and an ion fluid interacting with an electromagnetic field, expressed in Lagrangian variables. We perform a change of variables and make various approximations (eg. quasineutrality and ordering of the fields) and small parameter expansions directly in the action. The resulting equations of motion are then mapped to the Eulerian fluid variables using a novel nonlocal Lagrange-Euler map. The correct Eulerian equations are obtained after we impose locality. Using this method and the proper approximations and expansions, we recover Lust's general two-fluid model, extended MHD, Hall MHD, and Electron MHD from a unified framework. The variational formulation allows us to use Noether's theorem to derive conserved quantities for each symmetry of the action. U.S. Dept. of Energy Contract # DE-FG05-80ET-53088, Western New England University Research Fund.

  7. Fuel conservation and pollution control by MHD

    NASA Astrophysics Data System (ADS)

    Messerle, H. K.; Campbell, B.

    1980-06-01

    MHD generators, which directly convert thermal energy in a fluid into electricity, promise a more effective use of fuel for bulk power production than conventional steam plants, bettering efficiency by over 50% and reducing the generating cost by 20%. Using a Rankine steam cycle, overall power plant efficiency can increase from 33% to 50%, while fuel requirements can be reduced by one third and thermal pollution by one half. Since overall fuel consumption would drop, atmospheric pollution would be decreased, and coal consumption could be diverted to areas where oil is presently being used. The MHD generator structure and operation are discussed, and its general system requirements are explained. A table of energy use and an efficiency graph are provided for comparison purposes. Work is currently being done on a 2 MW open cycle MHD generator at the University of Sydney, Australia, and computer studies are in progress to evaluate the Faraday generator performance for the experimental 2 MW facility and larger power generators with segmented sets of electrodes.

  8. Multi-dimensional MHD simple waves

    SciTech Connect

    Webb, G. M.; Ratkiewicz, R.; Brio, M.; Zank, G. P.

    1996-07-20

    In this paper we consider a formalism for multi-dimensional simple MHD waves using ideas developed by Boillat. For simple wave solutions one assumes that all the physical variables (the density {rho}, gas pressure p, fluid velocity u, gas entropy S, and magnetic induction B in the MHD case) depend on a single phase function {phi}(r,t). The simple wave solution ansatz and the MHD equations then require that the phase function {phi} satisfies an implicit equation of the form f({phi})=r{center_dot}n({phi})-{lambda}({phi})t, where n({phi})={nabla}{phi}/|{nabla}{phi}| is the wave normal, {lambda}({phi})={omega}/k=-{phi}{sub t}/|{nabla}{phi}| is the normal speed of the wave front, and f({phi}) is an arbitrary differentiable function of {phi}. The formalism allows for more general simple waves than that usually dealt with in which n({phi}) is a constant unit vector that does not vary along the wave front. The formalism has implications for shock formation and wave breaking for multi-dimensional waves.

  9. Multi-dimensional MHD simple waves

    NASA Technical Reports Server (NTRS)

    Webb, G. M.; Ratkiewicz, R.; Brio, M.; Zank, G. P.

    1995-01-01

    In this paper we consider a formalism for multi-dimensional simple MHD waves using ideas developed by Boillat. For simple wave solutions one assumes that all the physical variables (the density rho, gas pressure p, fluid velocity V, gas entropy S, and magnetic induction B in the MHD case) depend on a single phase function phi(r,t). The simple wave solution ansatz and the MHD equations then require that the phase function has the form phi = r x n(phi) - lambda(phi)t, where = n(phi) = Delta phi / (absolute value of Delta phi) is the wave normal and lambda(phi) = omega/k = -phi t / (absolute value of Delta phi) is the normal speed of the wave front. The formalism allows for more general simple waves than that usually dealt with in which n(phi) is a constant unit vector that does not vary along the wave front. The formalism has implications for shock formation for multi-dimensional waves.

  10. Anisotropic MHD model and some solutions

    SciTech Connect

    Kuznetsov, V. D.; Dzhalilov, N. S.

    2010-09-15

    MHD waves and instabilities in a collisionless anisotropic-pressure plasma are analyzed in an anisotropic MHD model based on the 16-moment approximation, and the results are found to agree well with those obtained in the low-frequency limit of the kinetic model. It is shown that accounting for heat fluxes leads to an asymmetry in the phase velocities of the wave modes with respect to the heat flux direction and also to a strong interaction between the modes, especially between the backward ones (those that propagate in a direction opposite to that of the heat flux). A correct description of the mirror instability is given. The resonant interaction of three backward modes-fast acoustic, fast magnetosonic, and slow acoustic-under the conditions for the onset of the classical firehose instability triggers a new type of instability the growth rate of which is faster than the maximum growth rate of the conventional firehose instability. The results prove that, in contrast to the familiar Chew-Goldberger-Low approximate model, the anisotropic MHD approach provides a correct description of the large-scale dynamics of collisionless anisotropic plasmas (such as solar corona, solar wind, and ionospheric and magnetospheric plasmas).

  11. Stabilizing effect of resistivity towards ELM-free H-mode discharge in lithium-conditioned NSTX

    NASA Astrophysics Data System (ADS)

    Banerjee, Debabrata; Zhu, Ping; Maingi, Rajesh

    2017-07-01

    Linear stability analysis of the national spherical torus experiment (NSTX) Li-conditioned ELM-free H-mode equilibria is carried out in the context of the extended magneto-hydrodynamic (MHD) model in NIMROD. The purpose is to investigate the physical cause behind edge localized mode (ELM) suppression in experiment after the Li-coating of the divertor and the first wall of the NSTX tokamak. Besides ideal MHD modeling, including finite-Larmor radius effect and two-fluid Hall and electron diamagnetic drift contributions, a non-ideal resistivity model is employed, taking into account the increase of Z eff after Li-conditioning in ELM-free H-mode. Unlike an earlier conclusion from an eigenvalue code analysis of these equilibria, NIMROD results find that after reduced recycling from divertor plates, profile modification is necessary but insufficient to explain the mechanism behind complete ELMs suppression in ideal two-fluid MHD. After considering the higher plasma resistivity due to higher Z eff, the complete stabilization could be explained. A thorough analysis of both pre-lithium ELMy and with-lithium ELM-free cases using ideal and non-ideal MHD models is presented, after accurately including a vacuum-like cold halo region in NIMROD to investigate ELMs.

  12. Stabilizing effect of resistivity towards ELM-free H-mode discharge in lithium-conditioned NSTX

    DOE PAGES

    Banerjee, Debabrata; Zhu, Ping; Maingi, Rajesh

    2017-05-12

    Linear stability analysis of the national spherical torus experiment (NSTX) Li-conditioned ELM-free H-mode equilibria is carried out in the context of the extended magneto-hydrodynamic (MHD) model in NIMROD. Our purpose is to investigate the physical cause behind edge localized mode (ELM) suppression in experiment after the Li-coating of the divertor and the first wall of the NSTX tokamak. Besides ideal MHD modeling, including finite-Larmor radius effect and two-fluid Hall and electron diamagnetic drift contributions, a non-ideal resistivity model is employed, taking into account the increase of Z eff after Li-conditioning in ELM-free H-mode. And unlike an earlier conclusion from anmore » eigenvalue code analysis of these equilibria, NIMROD results find that after reduced recycling from divertor plates, profile modification is necessary but insufficient to explain the mechanism behind complete ELMs suppression in ideal two-fluid MHD. After considering the higher plasma resistivity due to higher Z eff, the complete stabilization could be explained. Furthermore, a thorough analysis of both pre-lithium ELMy and with-lithium ELM-free cases using ideal and non-ideal MHD models is presented, after accurately including a vacuum-like cold halo region in NIMROD to investigate ELMs.« less

  13. Gonorrhoea and gonococcal antimicrobial resistance surveillance networks in the WHO European Region, including the independent countries of the former Soviet Union.

    PubMed

    Unemo, Magnus; Ison, Catherine A; Cole, Michelle; Spiteri, Gianfranco; van de Laar, Marita; Khotenashvili, Lali

    2013-12-01

    Antimicrobial resistance (AMR) in Neisseria gonorrhoeae has emerged for essentially all antimicrobials following their introduction into clinical practice. During the latest decade, susceptibility to the last remaining options for antimicrobial monotherapy, the extended-spectrum cephalosporins (ESC), has markedly decreased internationally and treatment failures with these ESCs have been verified. In response to this developing situation, WHO and the European Centre for Disease Prevention and Control (ECDC) have published global and region-specific response plans, respectively. One main component of these action/response plans is to enhance the surveillance of AMR and treatment failures. This paper describes the perspectives from the diverse WHO European Region (53 countries), including the independent countries of the former Soviet Union, regarding gonococcal AMR surveillance networks. The WHO European Region has a high prevalence of resistance to all previously recommended antimicrobials, and most of the first strictly verified treatment failures with cefixime and ceftriaxone were also reported from Europe. In the European Union/European Economic Area (EU/EEA), the European gonococcal antimicrobial surveillance programme (Euro-GASP) funded by the ECDC is running. In 2011, the Euro-GASP included 21/31 (68%) EU/EEA countries, and the programme is further strengthened annually. However, in the non-EU/EEA countries, internationally reported and quality assured gonococcal AMR data are lacking in 87% of the countries and, worryingly, appropriate support for establishment of a GASP is still lacking. Accordingly, national and international support, including political and financial commitment, for gonococcal AMR surveillance in the non-EU/EEA countries of the WHO European Region is essential.

  14. NASA Lewis H2-O2 MHD program

    NASA Technical Reports Server (NTRS)

    Smith, M.; Nichols, L. D.; Seikel, G. R.

    1974-01-01

    Performance and power costs of H2-O2 combustion powered steam-MHD central power systems are estimated. Hydrogen gas is assumed to be transmitted by pipe from a remote coal gasifier into the city and converted to electricity in a steam MHD plant having an integral gaseous oxygen plant. These steam MHD systems appear to offer an attractive alternative to both in-city clean fueled conventional steam power plants and to remote coal fired power plants with underground electric transmission into the city. Status and plans are outlined for an experimental evaluation of H2-O2 combustion-driven MHD power generators at NASA Lewis Research Center.

  15. Effective method for MHD retrofit of power plants

    SciTech Connect

    Berry, G.F.; Dennis, C.B.; Johnson, T.R.; Minkov, V.

    1981-10-01

    Retrofitting existing power plants with an open-cycle MHD system has been re-examined in light of recent developments in the heat and seed recovery technology area. A new retrofit cycle configuration has been developed which provides for a direct gas-gas coupling; also, the MHD topping cycle can be decoupled from the existing plant for either separate or joint operation. As an example, the MHD retrofit concept has been applied to Illinois Power Company's Vermilion Station No. 1, a coal-fired power plant presently in operation. Substantial increases in efficiency have been demonstrated and the economic validity of the MHD retrofit approach has been established.

  16. Theoretical modelling of the feedback stabilization of external MHD modes in toroidal geometry

    NASA Astrophysics Data System (ADS)

    Chance, M. S.; Chu, M. S.; Okabayashi, M.; Turnbull, A. D.

    2002-03-01

    A theoretical framework for understanding the feedback mechanism for stabilization of external MHD modes has been formulated. Efficient computational tools - the GATO stability code coupled with a substantially modified VACUUM code - have been developed to effectively design viable feedback systems against these modes. The analysis assumed a thin resistive shell and a feedback coil structure accurately modelled in θ and phi, albeit with only a single harmonic variation in phi. Time constants and induced currents in the enclosing resistive shell are calculated. An optimized configuration based on an idealized model has been computed for the DIII-D device. Up to 90% of the effectiveness of an ideal wall can be achieved.

  17. Integron, Plasmid and Host Strain Characteristics of Escherichia coli from Humans and Food Included in the Norwegian Antimicrobial Resistance Monitoring Programs

    PubMed Central

    Sunde, Marianne; Simonsen, Gunnar Skov; Slettemeås, Jannice Schau; Böckerman, Inger; Norström, Madelaine

    2015-01-01

    Antimicrobial resistant Escherichia coli (n=331) isolates from humans with bloodstream infections were investigated for the presence of class 1 and class 2 integrons. The integron cassettes arrays were characterized and the findings were compared with data from similar investigations on resistant E. coli from meat and meat products (n=241) produced during the same time period. All isolates were obtained from the Norwegian monitoring programs for antimicrobial resistance in human pathogens and in the veterinary sector. Methods used included PCR, sequencing, conjugation experiments, plasmid replicon typing and subtyping, pulsed-field-gel-electrophoresis and serotyping. Integrons of class 1 and 2 occurred significantly more frequently among human isolates; 45.4% (95% CI: 39.9-50.9) than among isolates from meat; 18% (95% CI: 13.2 -23.3), (p<0.01, Chi-square test). Identical cassette arrays including dfrA1-aadA1, aadA1, dfrA12-orfF-aadA2, oxa-30-aadA1 (class 1 integrons) and dfrA1-sat1-aadA1 (class 2 integrons) were detected from both humans and meat. However, the most prevalent cassette array in human isolates, dfrA17-aadA5, did not occur in isolates from meat, suggesting a possible linkage between this class 1 integron and a subpopulation of E. coli adapted to a human host. The drfA1-aadA1 and aadA1 class 1 integrons were found frequently in both human and meat isolates. These isolates were subjected to further studies to investigate similarities with regard to transferability, plasmid and host strain characteristics. We detected incF plasmids with pMLST profile F24:A-:B1 carrying drfA1-aadA1 integrons in isolates from pork and in a more distantly related E. coli strain from a human with septicaemia. Furthermore, we showed that most of the class 1 integrons with aadA1 were located on incF plasmids with pMLST profile F51:A-:B10 in human isolates. The plasmid was present in unrelated as well as closely related host strains, demonstrating that dissemination of this

  18. Advanced MHD Algorithm for Solar and Space Science: lst Year Semi Annual Progress Report

    NASA Technical Reports Server (NTRS)

    Schnack, Dalton D.; Lionello, Roberto

    2003-01-01

    We report progress for the development of MH4D for the first and second quarters of FY2004, December 29, 2002 - June 6, 2003. The present version of MH4D can now solve the full viscous and resistive MHD equations using either an explicit or a semi-implicit time advancement algorithm. In this report we describe progress in the following areas. During the two last quarters we have presented poster at the EGS-AGU-EUG Joint Assembly in Nice, France, April 6-11, 2003, and a poster at the 2003 International Sherwood Theory Conference in Corpus Christi, Texas, April 28-30 2003. In the area of code development, we have implemented the MHD equations and the semi-implicit algorithm. The new features have been tested.

  19. Genotypic and Antimicrobial Susceptibility of Carbapenem-resistant Acinetobacter baumannii: Analysis of ISAba Elements and blaOXA-23-like Genes Including a New Variant

    PubMed Central

    Bahador, Abbas; Raoofian, Reza; Pourakbari, Babak; Taheri, Mohammad; Hashemizadeh, Zahra; Hashemi, Farhad B.

    2015-01-01

    Carbapenem-resistant Acinetobacter baumannii (CR-AB) causes serious nosocomial infections, especially in ICU wards of hospitals, worldwide. Expression of blaOXA genes is the chief mechanism of conferring carbapenem resistance among CR-AB. Although some blaOXA genes have been studied among CR-AB isolates from Iran, their blaOXA-23-like genes have not been investigated. We used a multiplex-PCR to detect Ambler class A, B, and D carbapenemases of 85 isolates, and determined that 34 harbored blaOXA-23-like genes. Amplified fragment length polymorphism (AFLP) genotyping, followed by DNA sequencing of blaOXA-23-like amplicons of CR-AB from each AFLP group was used to characterize their blaOXA-23-like genes. We also assessed the antimicrobial susceptibility pattern of CR-AB isolates, and tested whether they harbored insertion sequences ISAba1 and ISAba4. Sequence comparison with reference strain A. baumannii (NCTC12156) revealed five types of mutations in blaOXA-23-like genes; including one novel variant and four mutants that were already reported from China and the USA. All of the blaOXA-23-like genes mutations were associated with increased minimum inhibitory concentrations (MICs) against imipenem. ISAba1 and ISAba4 sequences were detected upstream of blaOXA-23 genes in 19 and 7% of isolates, respectively. The isolation of CR-AB with new blaOXA-23 mutations including some that have been reported from the USA and China highlights CR-AB pervasive distribution, which underscores the importance of concerted national and global efforts to control the spread of CR-AB isolates worldwide. PMID:26617588

  20. Genotypic and Antimicrobial Susceptibility of Carbapenem-resistant Acinetobacter baumannii: Analysis of is Aba Elements and bla OXA-23-like Genes Including a New Variant.

    PubMed

    Bahador, Abbas; Raoofian, Reza; Pourakbari, Babak; Taheri, Mohammad; Hashemizadeh, Zahra; Hashemi, Farhad B

    2015-01-01

    Carbapenem-resistant Acinetobacter baumannii (CR-AB) causes serious nosocomial infections, especially in ICU wards of hospitals, worldwide. Expression of bla OXA genes is the chief mechanism of conferring carbapenem resistance among CR-AB. Although some bla OXA genes have been studied among CR-AB isolates from Iran, their bla OXA-23-like genes have not been investigated. We used a multiplex-PCR to detect Ambler class A, B, and D carbapenemases of 85 isolates, and determined that 34 harbored bla OXA-23-like genes. Amplified fragment length polymorphism (AFLP) genotyping, followed by DNA sequencing of bla OXA-23-like amplicons of CR-AB from each AFLP group was used to characterize their bla OXA-23-like genes. We also assessed the antimicrobial susceptibility pattern of CR-AB isolates, and tested whether they harbored insertion sequences ISAba1 and ISAba4. Sequence comparison with reference strain A. baumannii (NCTC12156) revealed five types of mutations in bla OXA-23-like genes; including one novel variant and four mutants that were already reported from China and the USA. All of the bla OXA-23-like genes mutations were associated with increased minimum inhibitory concentrations (MICs) against imipenem. ISAba1 and ISAba4 sequences were detected upstream of bla OXA-23 genes in 19 and 7% of isolates, respectively. The isolation of CR-AB with new bla OXA-23 mutations including some that have been reported from the USA and China highlights CR-AB pervasive distribution, which underscores the importance of concerted national and global efforts to control the spread of CR-AB isolates worldwide.

  1. Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis

    PubMed Central

    Esposito, Susanna; Bosis, Samantha; Tadolini, Marina; Bianchini, Sonia; Migliori, Giovanni Battista; Principi, Nicola

    2016-01-01

    Abstract Rational: Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are emerging problems in several countries. These infections require long and expensive treatment regimens. Recently, 2 new drugs, bedaquiline and delamanid, have been approved in several countries for use in adults with severe, difficult-to-treat MDR-TB, and it has been suggested that they could also be administered to children with MDR-TB and limited treatment options. However, no study has been completed on their efficacy. Patient concerns: This report describes a 12-year-old child with XDR-TB who was cured after a 24-month therapy regimen, which included delamanid. Diagnoses: The patient showed progressive clinical deterioration after 5 months of treatment with the majority of anti-TB drugs available on the market. Interventions: After unsuccessfull treatment with several anti-TB drugs for 5 months, he was treated with a regimen including for 24 months. Outcomes: Direct smear microscopy of the gastric aspirates and gastric aspirate cultures for Mycobacterium tuberculosis became negative after only 1 week and remained persistently negative. During the 24-month treatment, all blood test results remained within the normal range, no adverse events were reported, and corrected QT interval was always normal. A clinical and laboratory control was performed 3 months after discontinuation of delamanid, and the other drugs did not reveal any modification of both general conditions as well as laboratory and radiological findings. The patient was considered cured. Lessons: The positive outcome associated with the favorable safety and tolerability profile showed that long-term therapy with delamanid can significantly contribute to treating apparently hopeless XDR-TB cases in children. PMID:27861363

  2. EDITORIAL: Selected papers from the 16th Workshop on MHD Stability Control: Optimizing and Understanding the Role of Coils for Mode Control Selected papers from the 16th Workshop on MHD Stability Control: Optimizing and Understanding the Role of Coils for Mode Control

    NASA Astrophysics Data System (ADS)

    La Haye, Rob

    2012-09-01

    The Magnetohydrodynamic (MHD) Control Workshop with the theme 'Optimizing and Understanding the Role of Coils for Mode Control' was held at General Atomics (20-22 November 2011) following the 2011 APS-DPP Annual Meeting in Salt Lake City, Utah (14-18 November). This was the 16th in the annual series and was organized jointly by Columbia University, General Atomics, Princeton Plasma Physics Laboratory, and the University of Wisconsin-Madison. Program committee participation included representatives from the EU and Japan along with other US laboratory and university institutions. This workshop highlighted the role of applied non-axisymmetric magnetic fields from both internal and external coils for control of MHD stability to achieve high performance fusion plasmas. The application of 3D magnetic field offers control of important elements of equilibrium, stability, and transport. The use of active 3D fields to stabilize global instabilities and to correct magnetic field errors is an established tool for achieving high beta configurations. 3D fields also affect transport and plasma momentum, and are shown to be important for the control of edge localized modes (ELMs), resistive wall modes, and optimized stellarator configurations. The format was similar to previous workshops, including 13 invited talks, 21 contributed talks, and this year there were 2 panel discussions ('Error Field Correction' led by Andrew Cole of Columbia University and 'Application of Coils in General' led by Richard Buttery of General Atomics). Ted Strait of General Atomics also gave a summary of the International Tokamak Physics Activity (ITPA) MHD meeting in Padua, a group for which he is now the leader. In this special section of Plasma Physics and Controlled Fusion (PPCF) is a sample of the presentations at the workshop, which have been subject to the normal refereeing procedures of the journal. They include a review (A Boozer) and an invited talk (R Fitzpatrick) on error fields, an invited

  3. Interfacing MHD Single Fluid and Kinetic Exospheric Solar Wind Models and Comparing Their Energetics

    NASA Astrophysics Data System (ADS)

    Moschou, Sofia-Paraskevi; Pierrard, Viviane; Keppens, Rony; Pomoell, Jens

    2017-09-01

    An exospheric kinetic solar wind model is interfaced with an observation-driven single-fluid magnetohydrodynamic (MHD) model. Initially, a photospheric magnetogram serves as observational input in the fluid approach to extrapolate the heliospheric magnetic field. Then semi-empirical coronal models are used for estimating the plasma characteristics up to a heliocentric distance of 0.1 AU. From there on, a full MHD model that computes the three-dimensional time-dependent evolution of the solar wind macroscopic variables up to the orbit of Earth is used. After interfacing the density and velocity at the inner MHD boundary, we compare our results with those of a kinetic exospheric solar wind model based on the assumption of Maxwell and Kappa velocity distribution functions for protons and electrons, respectively, as well as with in situ observations at 1 AU. This provides insight into more physically detailed processes, such as coronal heating and solar wind acceleration, which naturally arise from including suprathermal electrons in the model. We are interested in the profile of the solar wind speed and density at 1 AU, in characterizing the slow and fast source regions of the wind, and in comparing MHD with exospheric models in similar conditions. We calculate the energetics of both models from low to high heliocentric distances.

  4. On The Role of MHD Waves in Heating Localised Magnetic Structures

    NASA Astrophysics Data System (ADS)

    Erdélyi, R.; Nelson, C. J.

    2016-04-01

    Satellite and ground-based observations from e.g. SOHO, TRACE, STEREO, Hinode, SDO and IRIS to DST/ROSA, IBIS, CoMP, STT/CRISP have provided a wealth of evidence of waves and oscillations present in a wide range of spatial scales of the magnetised solar atmosphere. Our understanding about localised solar structures has been considerably changed in light of these high spatial and time resolution observations. However, MHD waves not only enable us to perform sub-resolution magneto-seismology of magnetic waveguides but are also potential candidates to carry and damp the necessary non-thermal energy in these localised waveguides. First, we will briefly outline the basic recent developments in MHD wave theory focussing on linear waves. Next, we discuss the role of the most frequently studied wave classes, including the Alfven, and magneto-acoustic kink and sausage waves. The current theoretical (and often difficult) interpretations of the detected solar atmospheric wave and oscillatory phenomena within the framework of MHD will be shown. Last, the latest reported observational findings of potential MHD wave flux, in terms of localised plasma heating, in the solar atmosphere is discussed, bringing us closer to solve the coronal heating problem.

  5. An unsplit Godunov method for ideal MHD via constrained transport in three dimensions

    NASA Astrophysics Data System (ADS)

    Gardiner, Thomas A.; Stone, James M.

    2008-04-01

    We present a single step, second-order accurate Godunov scheme for ideal MHD which is an extension of the method described in [T.A. Gardiner, J.M. Stone, An unsplit godunov method for ideal MHD via constrained transport, J. Comput. Phys. 205 (2005) 509] to three dimensions. This algorithm combines the corner transport upwind (CTU) method of Colella for multidimensional integration, and the constrained transport (CT) algorithm for preserving the divergence-free constraint on the magnetic field. We describe the calculation of the PPM interface states for 3D ideal MHD which must include multidimensional “MHD source terms” and naturally respect the balance implicit in these terms by the ∇·B=0 condition. We compare two different forms for the CTU integration algorithm which require either 6- or 12-solutions of the Riemann problem per cell per time-step, and present a detailed description of the 6-solve algorithm. Finally, we present solutions for test problems to demonstrate the accuracy and robustness of the algorithm.

  6. Development of MHD Wave Diagnostic and Models of Coronal Active Regions

    NASA Astrophysics Data System (ADS)

    Ofman, L.; Thompson, B. J.; Davila, J. M.

    2004-05-01

    We investigate the generation, propagation, and damping of MHD waves in active regions, with the goal to develop a diagnostic tool of active region structure, dynamics, and stability. We used 3D MHD model to study the generation and the propagation of EIT waves in a simple model of an active regions, and the interaction of EIT waves with the active region magnetic field. We model the oscillation of active region loops numerically using the 3D MHD model active regions. Such oscillations have been recently observed by TRACE. We use photospheric magnetograms as the boundary conditions for the magnetic field model, and construct an initial field using force-free extrapolation. Finite plasma temperature, density, and gravity are included in the model. We construct loop density structures in the model, guided by TRACE and EIT observations in the EUV. We demonstrate that by comparing the results of the MHD models of waves in an active region to observations we will be able to construct a diagnostic tool for the physical properties of the active regions, such as magnetic field and density structure.

  7. Multimegawatt nuclear electric propulsion with gaseous and vapor core reactors with MHD

    NASA Astrophysics Data System (ADS)

    Knight, Travis; Anghaie, Samim; Smith, Blair; Houts, Michael

    2001-02-01

    This study investigated the development of a system concept for space power generation and nuclear electric propulsion based on a fissioning plasma core reactor (FPCR) with magnetohydrodynamic (MHD) power conversion system, coupled to a magnetoplasmadynamic (MPD) thruster. The FPCR is a liquid-vapor core reactor concept operating with metallic uranium or uranium tetrafluoride (UF4) vapor as the fissioning fuel and alkali metals or their fluorides as working fluid in a closed Rankine cycle with MHD energy conversion. Candidate working fluids include K, Li, Na, KF, LiF, NaF, etc. The system features core outlet temperatures of 3000 to 4000 K at pressures of about 1 to 10 MPa, MHD temperatures of 2000 to 3000 K, and radiator temperatures of 1200 to 2000 K. This combination of parameters offers the potential for low total system specific mass in the range of 0.4 to 0.6 kg/kWe. The MHD output could be coupled with minimal power conditioning to the variable specific impulse magnetoplasma rocket (VASIMR), MPD thrusters or other types of thruster for producing thrust at very high specific impulse (Isp=1500 to 10,000 s). .

  8. MHD Integrated Topping Cycle Project. Thirteenth quarterly technical progress report, August 1, 1990--October 31, 1990

    SciTech Connect

    Not Available

    1992-01-01

    The overall objective of the project is to design and construct prototypical hardware for an integrated MHD topping cycle, and conduct long duration proof-of-concept tests of integrated system at the US DOE Component Development and Integration Facility in Butte, Montana. The results of the long duration tests will augment the existing engineering design data base on MHD power train reliability, availability, maintainability, and performance, and will serve as a basis for scaling up the topping cycle design to the next level of development, an early commercial scale power plant retrofit. The components of the MHD power train to be designed, fabricated, and tested include: A slagging coal combustor with a rated capacity of 50 MW thermal input, capable of operation with an Eastern (Illinois {number_sign}6) or Western (Montana Rosebud) coal, a segmented supersonic nozzle, a supersonic MHD channel capable of generating at least 1.5 MW of electrical power, a segmented supersonic diffuser section to interface the channel with existing facility quench and exhaust systems, a complete set of current control circuits for local diagonal current control along the channel, and a set of current consolidation circuits to interface the channel with the existing facility inverter.

  9. Analysis of Helicities and Hall and MHD Dynamo Effects in Two-Fluid Reversed-Field Pinch Simulations

    NASA Astrophysics Data System (ADS)

    Sauppe, Joshua; Sovinec, Carl

    2015-11-01

    Relaxation in the RFP is studied numerically with extended-MHD modeling that includes the Hall term and ion gyroviscous stress. Previous results show significant coupling between magnetic relaxation and parallel flow evolution [King PoP 19, 055905]. Computations presented here display quasi-periodic relaxation events with current relaxation through MHD and Hall dynamo drives. The MHD dynamo always relaxes currents while the Hall dynamo may add or subtract from it, but the total dynamo drive is similar to single-fluid MHD computations. Changes in plasma momentum are due to viscous coupling to the wall and fluctuation-induced Maxwell stresses transport momentum radially inward when two-fluid effects are included. The magnetic helicity and hybrid helicity, a two-fluid extension of magnetic helicity that includes cross and kinetic helicity [Turner, 1986], are well-conserved relative to magnetic energy at each event. The cross helicity is well-conserved in single-fluid MHD but is significantly affected by both two-fluid effects and ion gyroviscosity. The plasma parallel current evolves towards the predicted flat profile; however, the plasma flow does not. Work supported through NSF grant PHY-0821899 and DOE grant DE-FG02-06ER54850.

  10. Changes in the six most common sequence types of Neisseria gonorrhoeae, including ST4378, identified by surveillance of antimicrobial resistance in northern Taiwan from 2006 to 2013.

    PubMed

    Cheng, Ching-Wai; Li, Lan-Hui; Su, Chen-Yi; Li, Shu-Ying; Yen, Muh-Yong

    2016-10-01

    There has been no longitudinal study of drug susceptibility in Neisseria gonorrhoeae in Taiwan since 2006. We collected 1090 gonococcal isolates from Taipei City Hospital, Taiwan from April 2006 to August 2013. We used a disk diffusion assay to determine the susceptibility to five antibiotics and an E-test to determine the minimum inhibitory concentrations for cefixime and ceftriaxone in isolates with resistance. Neisseria gonorrhoeae-multi Antigen Sequence Typing and DNA sequencing of the por and tbpB genes were used to identify sequence types. Among the 1090 isolates, the resistances to penicillin, ciprofloxacin, cefpodoxime, cefixime, and ceftriaxone were 61.01%, 83.39%, 9.63%, 6.70%, and 2.39%, respectively. The highest minimum inhibitory concentrations of cefixime and ceftriaxone were 0.19 mg/L and 0.50 mg/L, respectively. There were 327 sequence types. The four most common sequence types in homosexuals were ST4378, ST359, ST4654, and ST547; the two most common sequence types in heterosexuals were ST421 and ST419. Each of these sequence types had more than 25 isolates. There were significant differences in the sequence types in patients with different sexual orientations (p < 0.001). Oral cefixime or ceftriaxone injections were used as first-line drugs for the treatment of gonorrhea from 2006 to 2013 because gonorrhea isolates had low minimum inhibitory concentrations for these two drugs. The abrupt emergence of ST4378 (closely related to the notorious ST1407) since 2009 is a cause for alarm. Changes in sexual behavior, including an increase in sexual activity without the use of condoms, may have contributed to the peak in gonorrhea in 2010. Further molecular epidemiological investigations are required. Copyright © 2014. Published by Elsevier B.V.

  11. Magnetohydrodynamic (MHD) driven droplet mixer

    DOEpatents

    Lee, Abraham P.; Lemoff, Asuncion V.; Miles, Robin R.

    2004-05-11

    A magnetohydrodynamic fluidic system mixes a first substance and a second substance. A first substrate section includes a first flow channel and a first plurality of pairs of spaced electrodes operatively connected to the first flow channel. A second substrate section includes a second flow channel and a second plurality of pairs of spaced electrodes operatively connected to the second flow channel. A third substrate section includes a third flow channel and a third plurality of pairs of spaced electrodes operatively connected to the third flow channel. A magnetic section and a control section are operatively connected to the spaced electrodes. The first substrate section, the second substrate section, the third substrate section, the first plurality of pairs of spaced electrodes, the second plurality of pairs of spaced electrodes, the third plurality of pairs of spaced electrodes, the magnetic section, and the control section are operated to move the first substance through the first flow channel, the second substance through the second flow channel, and both the first substance and the second substance into the third flow channel where they are mixed.

  12. NONLINEAR MHD WAVES IN A PROMINENCE FOOT

    SciTech Connect

    Ofman, L.; Knizhnik, K.; Kucera, T.; Schmieder, B.

    2015-11-10

    We study nonlinear waves in a prominence foot using a 2.5D MHD model motivated by recent high-resolution observations with Hinode/Solar Optical Telescope in Ca ii emission of a prominence on 2012 October 10 showing highly dynamic small-scale motions in the prominence material. Observations of Hα intensities and of Doppler shifts show similar propagating fluctuations. However, the optically thick nature of the emission lines inhibits a unique quantitative interpretation in terms of density. Nevertheless, we find evidence of nonlinear wave activity in the prominence foot by examining the relative magnitude of the fluctuation intensity (δI/I ∼ δn/n). The waves are evident as significant density fluctuations that vary with height and apparently travel upward from the chromosphere into the prominence material with quasi-periodic fluctuations with a typical period in the range of 5–11 minutes and wavelengths <2000 km. Recent Doppler shift observations show the transverse displacement of the propagating waves. The magnetic field was measured with the THEMIS instrument and was found to be 5–14 G. For the typical prominence density the corresponding fast magnetosonic speed is ∼20 km s{sup −1}, in qualitative agreement with the propagation speed of the detected waves. The 2.5D MHD numerical model is constrained with the typical parameters of the prominence waves seen in observations. Our numerical results reproduce the nonlinear fast magnetosonic waves and provide strong support for the presence of these waves in the prominence foot. We also explore gravitational MHD oscillations of the heavy prominence foot material supported by dipped magnetic field structure.

  13. MHD Turbulence at Moderate Magnetic Reynolds Number

    NASA Technical Reports Server (NTRS)

    Knaepen, B.; Kassinos, S.; Carati, D.

    2003-01-01

    In the present article we will consider the decay of MHD turbulence under the influence of a strong external magnetic field at moderate magnetic Reynolds numbers. Typical values of R(sub m) that are considered here range from R(sub m) approx. 0.1 to R(sub m) approx. 20. As a comparison, the initial kinetic Reynolds number common to all our simulations is Re(sub L) = 199. This means that the range of Prandtl numbers explored is 5 x 10(exp -4) to 10(exp -1). Our motivation is mainly to exhibit how the transition from the QS approximation to FMHD occurs. At the lowest values of R(sub m) studied here, the QS approximation is shown to model the flow faithfully. However, for the higher values of R(sub m) considered, it is clearly inadequate but can be replaced by another approximation which will be referred to as the Quasi-Linear (QL) approximation. Another objective of the present study is to describe how variations in the magnetic Reynolds number (while maintaining all other parameters constant) affect the dynamics of the flow. This complements past studies where variations in either the strength of the external magnetic field or the kinetic Reynolds number were considered. This article is organized as follows. In section 2 we recall the definition of the quasi-static approximation. Section 3 is devoted to the description of the numerical experiments performed using the quasi-static approximation and full MHD. In section 4 we describe the quasi-linear approximation and test it numerically against full MHD. A concluding summary is given in section 5.

  14. Nonlinear MHD Waves in a Prominence Foot

    NASA Astrophysics Data System (ADS)

    Ofman, L.; Knizhnik, K.; Kucera, T.; Schmieder, B.

    2015-11-01

    We study nonlinear waves in a prominence foot using a 2.5D MHD model motivated by recent high-resolution observations with Hinode/Solar Optical Telescope in Ca ii emission of a prominence on 2012 October 10 showing highly dynamic small-scale motions in the prominence material. Observations of Hα intensities and of Doppler shifts show similar propagating fluctuations. However, the optically thick nature of the emission lines inhibits a unique quantitative interpretation in terms of density. Nevertheless, we find evidence of nonlinear wave activity in the prominence foot by examining the relative magnitude of the fluctuation intensity (δI/I ˜ δn/n). The waves are evident as significant density fluctuations that vary with height and apparently travel upward from the chromosphere into the prominence material with quasi-periodic fluctuations with a typical period in the range of 5-11 minutes and wavelengths <2000 km. Recent Doppler shift observations show the transverse displacement of the propagating waves. The magnetic field was measured with the THEMIS instrument and was found to be 5-14 G. For the typical prominence density the corresponding fast magnetosonic speed is ˜20 km s-1, in qualitative agreement with the propagation speed of the detected waves. The 2.5D MHD numerical model is constrained with the typical parameters of the prominence waves seen in observations. Our numerical results reproduce the nonlinear fast magnetosonic waves and provide strong support for the presence of these waves in the prominence foot. We also explore gravitational MHD oscillations of the heavy prominence foot material supported by dipped magnetic field structure.

  15. Annular MHD Physics for Turbojet Energy Bypass

    NASA Technical Reports Server (NTRS)

    Schneider, Steven J.

    2011-01-01

    The use of annular Hall type MHD generator/accelerator ducts for turbojet energy bypass is evaluated assuming weakly ionized flows obtained from pulsed nanosecond discharges. The equations for a 1-D, axisymmetric MHD generator/accelerator are derived and numerically integrated to determine the generator/accelerator performance characteristics. The concept offers a shockless means of interacting with high speed inlet flows and potentially offers variable inlet geometry performance without the complexity of moving parts simply by varying the generator loading parameter. The cycle analysis conducted iteratively with a spike inlet and turbojet flying at M = 7 at 30 km altitude is estimated to have a positive thrust per unit mass flow of 185 N-s/kg. The turbojet allowable combustor temperature is set at an aggressive 2200 deg K. The annular MHD Hall generator/accelerator is L = 3 m in length with a B(sub r) = 5 Tesla magnetic field and a conductivity of sigma = 5 mho/m for the generator and sigma= 1.0 mho/m for the accelerator. The calculated isentropic efficiency for the generator is eta(sub sg) = 84 percent at an enthalpy extraction ratio, eta(sub Ng) = 0.63. The calculated isentropic efficiency for the accelerator is eta(sub sa) = 81 percent at an enthalpy addition ratio, eta(sub Na) = 0.62. An assessment of the ionization fraction necessary to achieve a conductivity of sigma = 1.0 mho/m is n(sub e)/n = 1.90 X 10(exp -6), and for sigma = 5.0 mho/m is n(sub e)/n = 9.52 X 10(exp -6).

  16. MHD Electrode and wall constructions

    DOEpatents

    Way, Stewart; Lempert, Joseph

    1984-01-01

    Electrode and wall constructions for the walls of a channel transmitting the hot plasma in a magnetohydrodynamic generator. The electrodes and walls are made of a plurality of similar modules which are spaced from one another along the channel. The electrodes can be metallic or ceramic, and each module includes one or more electrodes which are exposed to the plasma and a metallic cooling bar which is spaced from the plasma and which has passages through which a cooling fluid flows to remove heat transmitted from the electrode to the cooling bar. Each electrode module is spaced from and electrically insulated from each adjacent module while interconnected by the cooling fluid which serially flows among selected modules. A wall module includes an electrically insulating ceramic body exposed to the plasma and affixed, preferably by mechanical clips or by brazing, to a metallic cooling bar spaced from the plasma and having cooling fluid passages. Each wall module is, similar to the electrode modules, electrically insulated from the adjacent modules and serially interconnected to other modules by the cooling fluid.

  17. Magnetogasdynamic Phenomena in Pulsed MHD Flows.

    DTIC Science & Technology

    1979-10-01

    r D-A079 919 STD RESEARCH CORP ARCADIA CALIF F/a 20/9 VA NETOGASDYNAMIC PHENODE’A IN PULSED MHD FLOWS.(U) OCT 79 D A OLIVER, T F SWEAN. D M MARKHAN...N00014-77-C-0574 UNCLASSIFIED STD -UP-002-77-1 NL ".’ rnunnnnunnnnSllflflflflflflf lllll /////IlEEEEE//!i *fl///////lfl l I/fflIEN I2) STD -UP-002-77-1...DEMETRIADES OCTOBER 1979 --A li JTlrSUMMARY REPORT FOR THE PERIOD 1 OCTOBER 1978 THROUGH 30 SEPTEMBER 1979 STD RESEARCH CORPORATION ARCADIA, CA S1006 PREPARED

  18. Local potential analysis of MHD instability

    NASA Astrophysics Data System (ADS)

    Sen, K. K.; Wilson, S. J.

    1985-02-01

    The use of the local potential method for studying instabilities of MHD fluids is examined. The mathematical method is similar to that developed by the authors for studying the time-dependent radiative transfer problem and the radiative stability of interstellar masers. The scheme is based on the universal evolution criterion proposed by Glansdorff and Prigogine (1964) as demonstrated by Hays (1965) for the heat equation and Schechter and Himmelblau (1965) for the Benard problem in hydrodynamics. The scheme for securing stability criteria is demonstrated for two particular cases.

  19. High Power Pulsed Plasma MHD Experiments.

    DTIC Science & Technology

    1982-09-30

    VV 410 0 ’-4 U - $4 V-4’ (rD~~lrtU) rzO3 vlqu A are calculated using the Rogov formulation (Reference 6) and a modified Debye - Huckel equation-of...agrees well with the modified Debye - Huckel equation-of- state at the lower density conditions encountered in the MHD generator. We have devoted...the generator. A de- * tailed description of the theory and operation of these diagnostics is available in References 3 and 5. Attempts were made to

  20. Instability of periodic MHD shear flows

    SciTech Connect

    Zaqarashvili, T.V.; Oliver, R.; Ballester, J.L.; Belvedere, G.

    2004-11-12

    The stability of periodic MHD shear flows generated by an external transversal periodic force in magnetized plasma is studied. It is shown that the temporal behaviour of magnetosonic wave spatial Fourier harmonics in such flows is governed by Mathieu equation. Consequently the harmonics with the half frequency of the shear flows grow exponentially in time. Therefore the periodic shear motions are unstable to the perturbations of compressible magnetosonic waves. The motions represent the kinetic part of the transversal oscillation in magnetized plasma. Therefore due to the instability of periodic shear motions, the transversal oscillations may quickly be damped, so transferring their energy to compressible magnetosonic perturbations.

  1. MHD bending waves in a current sheet

    NASA Technical Reports Server (NTRS)

    Musielak, Z. E.; Suess, S. T.

    1986-01-01

    Transverse MHD bending waves are considered in an isothermal and compressible two-dimensional current sheet of finite thickness in which the magnetic field changes direction and strength. The general form of the wave equation is obtained. It is shown that rotation of the magnetic field across the current sheet prevents the existence of singular points so that continuous spectrum solutions and the concomitant wave decay disappear. Instead, normal modes exist and closed integral solution for arbitrary current sheet structure are found. The results are discussed in terms of small-scale waves on the heliospheric current sheet.

  2. MHD oxidant intermediate temperature ceramic heater study

    NASA Technical Reports Server (NTRS)

    Carlson, A. W.; Chait, I. L.; Saari, D. P.; Marksberry, C. L.

    1981-01-01

    The use of three types of directly fired ceramic heaters for preheating oxygen enriched air to an intermediate temperature of 1144K was investigated. The three types of ceramic heaters are: (1) a fixed bed, periodic flow ceramic brick regenerative heater; (2) a ceramic pebble regenerative heater. The heater design, performance and operating characteristics under conditions in which the particulate matter is not solidified are evaluated. A comparison and overall evaluation of the three types of ceramic heaters and temperature range determination at which the particulate matter in the MHD exhaust gas is estimated to be a dry powder are presented.

  3. Benefits of a 12-week lifestyle modification program including diet and combined aerobic and resistance exercise on albuminuria in diabetic and non-diabetic Japanese populations.

    PubMed

    Yamamoto-Kabasawa, Keiko; Hosojima, Michihiro; Yata, Yusuke; Saito, Mariko; Tanaka, Noriko; Tanaka, Junta; Tanabe, Naohito; Narita, Ichiei; Arakawa, Masaaki; Saito, Akihiko

    2015-12-01

    Albuminuria is a biomarker for chronic kidney disease and an independent predictor of cardiovascular and all-cause mortality. A recent meta-analysis concluded that these risks increase with urinary albumin concentration, even when below the microalbuminuria threshold. Thus, minimizing urinary albumin may be a valuable therapeutic goal regardless of disease status. We investigated the benefits and safety of a 12-week lifestyle modification program including diet and combined aerobic and resistance exercise for reducing albuminuria in 295 normoalbuminuric or microalbuminuric Japanese adults, including 30 with type 2 diabetes mellitus (T2DM), 104 with metabolic syndrome (MS), and 145 with hypertension (HT). In the study population, the urinary albumin:creatinine ratio (UACR) was reduced significantly (ΔUACR -3.8 ± 16.8 mg/g, P < 0.001) with no change in estimated glomerular filtration rate (eGFR) (ΔeGFR -0.4 ± 7.4 mL/min/1.73 m(2), P = 0.343). The reduction in UACR was associated with decreased fasting plasma glucose (P < 0.05). The UACR was also reduced in the T2DM, MS, and HT groups with no change in eGFR. Reduced UACR was associated with decreased fasting plasma glucose in the MS group and decreased systolic blood pressure in the HT group. The UACR was also reduced in 46 subjects using renin-angiotensin system inhibitors with no change in eGFR. Our 12-week lifestyle modification program reduced UACR, maintained eGFR, and improved multiple fitness findings in Japanese subjects including T2DM, MS, and HT patients.

  4. MHD Integrated Topping Cycle Project

    NASA Astrophysics Data System (ADS)

    1993-04-01

    Manufacture, assembly, and checkout of combustion subsystem hardware was completed and the hardware was delivered to CDIF along with the water electrical isolators. A successful nozzle proof test was concluded; its purpose was to evaluate adequacy of the nozzle structure and sealing of sidewall-to-electrode wall joints, water tubes, and stud and wire penetrations at operating pressure. Design modifications to spare channel inlet frame were made to enable iron oxide injection. Results of tests in the CDIF 1A1 channel which compared effect of different cathode wall iron oxide injection locations indicated that injection through the side port may be more effective, particularly if one of the two ports becomes clogged. Design confirmation testing of a pneumatically driven ram to clear a plugged iron oxide injector tip was performed. Manufacture of spare and replacement parts for 1A4 channel and diffuser was begun. Construction of the cathode power cabinets and associated control system was completed. Hot-fire checkout series was completed for the combustion subsystem; 16.8 thermal hours were accumulated during seven tests. This test series demonstrated adequacy of overall cooling of combustion subsystem and provided an initial evaluation of heat losses and slagging characteristics. Several major facility activities at the CDIF were accomplished including installation and testing of new iron oxide pumps, initial on-line checkout of coal feed system modifications, modification of seed system including replacement of silo rotary feeder, installation of new filter receiver on the silo, conversion of fly ash bin to dust collector, removal of all of the electrical wiring (used for 1A1 channel) between the channel and HVR in order to install 1A4 wiring, and installation of the 1A4 channel.

  5. Stellarator expansion methods for MHD equilibrium and stability calculations

    SciTech Connect

    Lynch, V.E.; Charlton, L.A.; Hicks, H.R.; Holmes, J.A.; Carreras, B.A.; Hender, T.C.; Garcia, L.

    1986-03-01

    Two methods for performing stellarator expansion, or average method, MHD calculations are described. The first method includes the calculation of vacuum, equilibrium, and stability, using the Greene and Johnson stellarator expansion in which the equilibrium is reduced to a 2-D problem by averaging over the geometric toroidal angle in real space coordinates. In the second method, the average is performed in a system of vacuum magnetic coordinates. Both methods are implemented to utilize realistic vacuum field information, making them applicable to configuration studies and machine design, as well as to basic research. Illustrative examples are presented to detail the sensitivities of the calculations to physical parameters and to show numerical convergence and the comparison of these methods with each other and with other methods.

  6. MHD simulations of coronal dark downflows considering thermal conduction

    NASA Astrophysics Data System (ADS)

    Zurbriggen, E.; Costa, A.; Esquivel, A.; Schneiter, M.; Cécere, M.

    2017-10-01

    While several scenarios have been proposed to explain supra-arcade downflows (SADs) observed descending through turbulent hot regions, none of them have systematically addressed the consideration of thermal conduction. The SADs are known to be voided cavities. Our model assumes that SADs are triggered by bursty localized reconnection events that produce non-linear waves generating the voided cavity. These subdense cavities are sustained in time because they are hotter than their surrounding medium. Due to the low density and large temperature values of the plasma we expect the thermal conduction to be an important process. Our main aim here is to study if it is possible to generate SADs in the framework of our model considering thermal conduction. We carry on 2D MHD simulations including anisotropic thermal conduction, and find that if the magnetic lines envelope the cavities, they can be isolated from the hot environment and be identified as SADs.

  7. An MHD Model of the Solar Corona and Solar Wind

    NASA Astrophysics Data System (ADS)

    Mikic, Z.; Linker, J. A.; Colborn, J. A.

    1996-05-01

    The structure of the heliosphere, especially the regions of fast and slow solar wind, are strongly influenced by coronal magnetic structure near the Sun. Favorable comparisons between three-dimensional MHD models of the solar corona and eclipse observations have shown that it is possible to model the structure of the large-scale solar corona. However, these models use a simplified energy equation, in which the plasma is assumed to obey an adiabatic energy equation with a reduced polytropic index. As a consequence, even though the predicted streamer structure in the corona agrees fairly well with eclipse observations, the predicted solar wind speed is not realistic. We have improved this model by adding important dynamic and thermodynamic effects, including the presence of a transition region, thermal conduction, radiation, coronal heating, and Alfven wave acceleration. We will present results obtained with this improved model on the structure of the solar corona and solar wind.

  8. Transpiration cooled electrodes and insulators for MHD generators

    DOEpatents

    Hoover, Jr., Delmer Q.

    1981-01-01

    Systems for cooling the inner duct walls in a magnetohydrodynamic (MHD) generator. The inner face components, adjacent the plasma, are formed of a porous material known as a transpiration material. Selected cooling gases are transpired through the duct walls, including electrically insulating and electrode segments, and into the plasma. A wide variety of structural materials and coolant gases at selected temperatures and pressures can be utilized and the gases can be drawn from the generation system compressor, the surrounding environment, and combustion and seed treatment products otherwise discharged, among many other sources. The conduits conducting the cooling gas are electrically insulated through low pressure bushings and connectors so as to electrically isolate the generator duct from the ground.

  9. V3FIT: Three-Dimensional MHD Equilibrium Reconstruction

    NASA Astrophysics Data System (ADS)

    Hanson, James D.; Shields, John; Hirshman, S. P.; Lazarus, E. A.; Lao, L.; Knowlton, S. F.

    2007-11-01

    V3FIT is a three-dimensional MHD equilibrium reconstruction code, based on the VMEC equilibrium code. V3FIT is a general and easily extensible reconstruction code, designed so that information from many types of diagnostics can be used to determine the equilibrium. The first diagnostics included in V3FIT were magnetic diagnostics. We will present results on reconstruction using microwave interferometers and polarimeters as diagnostics. We will also show comparisons between V3FIT and EFIT reconstructions using experimental data from the DIII-D tokamak. This work is supported in part by US DOE Grant DE-FG02-03ER54692B and a US DOE Postdoctoral Research Fellowship.

  10. Tracking Changes in Magnetic Topology in MHD Simulations

    NASA Astrophysics Data System (ADS)

    Mikic, Z.; Titov, V. S.; Lionello, R.; Torok, T.; Linker, J.; Downs, C.

    2016-12-01

    The topology of the coronal magnetic field plays a key role in the properties of the corona and the source of the slow solar wind. The concept of slip-back mapping (Titov et al. 2009) has been applied to detect open, closed, and disconnected flux systems formed by reconnection of coronal magnetic fields during a given time interval. In particular, this technique can identify regions where closed magnetic field lines became open (e.g., via interchange reconnection), and conversely, where open field lines became closed. We will describe the application of this technique to the analysis of 3D MHD simulations (including those of coronal jets and the propagation of "blobs" in the solar wind). Research supported by NASA's Living With a Star Program.

  11. Test of an MHD code for cosmological applications

    NASA Astrophysics Data System (ADS)

    Stasyszyn, F.; Dolag, K.

    2009-08-01

    We build up a comprehensive MHD test suit containing various shock tube tests and different planar MHD test problems (like the Orzang-Tang Vortex, Blast Waves and a Rotor test). To test the MHD implementation (Dolag & Stasyszyn, in prep.) within the cosmological SPH code Gadget 13, we performed fully consistently three dimensional setups to test the code under the same conditions as used the cosmological applications. The results were compared with the idealized solutions obtained in 1D/2D using Athena 3.0 (Gardiner & Stone 2006), showing us that the SPH MHD implementation performs very well. We also compare different regularization schemes of SPH MHD suggested in the literature, and calibrate theses schemes inferring optimal values for the numerical parameters involved. The Implementation of a Hyperbolic/Parabolic divergence cleaning scheme as suggested by Dedner (Dedner et al. 2002) have been also tested, finding good agreement with the results reported in the literature (Price & Monaghan 2005).

  12. The development of MHD energy conversion methods in the USSR

    NASA Astrophysics Data System (ADS)

    Kirillin, V. A.; Sheindlin, A. E.

    1981-12-01

    It is noted that the development of magnetohydrodynamic (MHD) power conversion systems has evolved to the point where it is possible to commercially introduce MHD power plants into industry. Even with the present level of technology, the sharp increase in thermal efficiency of these plants by as much as 50-60% results in fuel economies of 20-35% and in reductions in generation costs of 6-7%. A description is given of an MHD power plant and its various aggregates. Also given are a review of the state of the art of MHD technology and an outline of the Soviet program for its commercial exploitation. The design of MHD electrical power plants, the interrelation between various aggregates, and the problems arising from nonstandard equipment are discussed.

  13. Results from conceptual design study of potential early commercial MHD/steam power plants

    NASA Technical Reports Server (NTRS)

    Hals, F.; Kessler, R.; Swallom, D.; Westra, L.; Zar, J.; Morgan, W.; Bozzuto, C.

    1981-01-01

    This paper presents conceptual design information for a potential early MHD power plant developed in the second phase of a joint study of such plants. Conceptual designs of plant components and equipment with performance, operational characteristics and costs are reported on. Plant economics and overall performance including full and part load operation are reviewed. Environmental aspects and the methods incorporated in plant design for emission control of sulfur and nitrogen oxides are reviewed. Results from reliability/availability analysis conducted are also included.

  14. Results from conceptual design study of potential early commercial MHD/steam power plants

    NASA Technical Reports Server (NTRS)

    Hals, F.; Kessler, R.; Swallom, D.; Westra, L.; Zar, J.; Morgan, W.; Bozzuto, C.

    1981-01-01

    This paper presents conceptual design information for a potential early MHD power plant developed in the second phase of a joint study of such plants. Conceptual designs of plant components and equipment with performance, operational characteristics and costs are reported on. Plant economics and overall performance including full and part load operation are reviewed. Environmental aspects and the methods incorporated in plant design for emission control of sulfur and nitrogen oxides are reviewed. Results from reliability/availability analysis conducted are also included.

  15. MHD shocks in the ISM

    NASA Technical Reports Server (NTRS)

    Chernoff, D. F.; Hollenbach, David J.; Mckee, Christopher F.

    1990-01-01

    Researchers survey shock solutions of a partially ionized gas with a magnetic field. The gas is modeled by interacting neutral, ion, electron and charged grain components. They employ a small neutral-ion chemical network to follow the dissociation and ionization of the major species. Cooling by molecular hydrogen (rotational, vibrational and dissociation), grains and dipole molecules is included. There are three basic types of solutions (C, C asterisk, and J) and some more complicated flows involving combinations of the basic types. The initial preshock conditions cover hydrogen nuclei densities of 1 less than n less than 10(exp 10) cm(-3) and shock velocities of 5 less than v(sub s) less than 60 km/s. The magnetic field is varied over 5 decades and the sensitivity of the results to grain parameters, UV and cosmic ray fluxes is ascertained. The parameter space is quite complicated, but there exist some simple divisions. When the initial ionization fraction is small (chi sub i less than 10(-5)), there is a sharp transition between fully C solutions at low velocity and strong J solutions at high velocity. When the initial ionization fraction is larger, C asterisk and/or very weak J shocks are present at low velocities in addition to the C solutions. The flow again changes to strong J shocks at high velocities. When the ionization fraction is large and the flow is only slightly greater than the bulk Alfven velocity, there is a complicated mixture of C, C asterisk and J solutions.

  16. Structural organization and expression of amplified chromosomal sequences, which include the rudimentary gene, in cultured Drosophila cells resistant to N-(phosphonacetyl)-L-aspartate.

    PubMed

    Laval, M; Azou, Y; Miassod, R

    1989-12-01

    We have used 160 kilobases of cloned Drosophila genomic DNA from the rudimentary (r) region to examine the organization of amplified DNA in Drosophila cells resistant to 10 mM N-(phosphonacetyl)-L-aspartate (PALAr cells) obtained by stepwise selection. Evidence for the direct tandem linkage of the amplified sequences is presented. The pattern and intensity of amplified bands as well as the presence of novel junctions in the DNA sequence of PALAr cells indicate that there are two types of units of 150 and 120 kilobases long. The sequence of the smaller unit is entirely included within the larger one. The longer of the two units is present twice while the shorter one is amplified eightfold as compared to the level of the relevant DNA sequences in the wild-type. These data are consistent with a model in which successive crossing-over events over several cell cycles lead to amplification of the selected r gene and flanking sequences. However, these data can also be accounted for by a totally different mechanism in which multiple copies of DNA are generated by rolling circle replication. Transcription units other than the r gene are present within the 150 kilobase region of amplified DNA. These are found to be overexpressed in PALAr cells, though some transcripts are underrepresented relative to the copy number of the corresponding coding sequences.

  17. In Vitro Antibacterial and Antibiofilm Activities of Chlorogenic Acid against Clinical Isolates of Stenotrophomonas maltophilia including the Trimethoprim/Sulfamethoxazole Resistant Strain

    PubMed Central

    Karunanidhi, Arunkumar; Thomas, Renjan; van Belkum, Alex; Neela, Vasanthakumari

    2013-01-01

    The in vitro antibacterial and antibiofilm activity of chlorogenic acid against clinical isolates of Stenotrophomonas maltophilia was investigated through disk diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), time-kill and biofilm assays. A total of 9 clinical S. maltophilia isolates including one isolate resistant to trimethoprim/sulfamethoxazole (TMP/SMX) were tested. The inhibition zone sizes for the isolates ranged from 17 to 29 mm, while the MIC and MBC values ranged from 8 to 16 μg mL−1 and 16 to 32 μg mL−1. Chlorogenic acid appeared to be strongly bactericidal at 4x MIC, with a 2-log reduction in viable bacteria at 10 h. In vitro antibiofilm testing showed a 4-fold reduction in biofilm viability at 4x MIC compared to 1x MIC values (0.085 < 0.397 A 490 nm) of chlorogenic acid. The data from this study support the notion that the chlorogenic acid has promising in vitro antibacterial and antibiofilm activities against S. maltophilia. PMID:23509719

  18. Nonlinear tearing mode study using the almost ideal magnetohydrodynamics (MHD) constraint

    SciTech Connect

    Ren, C.; Callen, J.D.; Jensen, T.H.

    1998-12-31

    The tearing mode is an important resistive magnetohydrodynamics (MHD) mode. It perturbs the initial equilibrium magnetic flux surfaces through magnetic field line reconnection to form new flux surfaces with magnetic islands. In the study of the tearing mode, usually the initial equilibria are one dimensional with two ignorable coordinates and the perturbed equilibria are two dimensional with one ignorable coordinate. The tearing mode can be linearly unstable and its growth saturates at a fine amplitude. The neoclassical tearing mode theory shows that the mode can be nonlinearly driven by the bootstrap current even when it is linearly stable to the classical tearing mode. It is important to study the nonlinear behavior of the tearing mode. As an intrinsically nonlinear approach, the use of the almost ideal MHD constraint is suited to study the nonlinear properties of the tearing mode. In this paper, as a validation of the method, the authors study two characteristics of the tearing mode using the almost ideal MHD constraint: (1) the linear stability condition for the initial one dimensional equilibrium; and (2) the final saturation level for the unstable case. In this work, they only consider the simplest case where no gradient of pressure or current density exists at the mode resonant surface.

  19. SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

    PubMed

    Watanabe, Reiko; Ui, Ayako; Kanno, Shin-Ichiro; Ogiwara, Hideaki; Nagase, Takahiro; Kohno, Takashi; Yasui, Akira

    2014-05-01

    The SWI/SNF chromatin-remodeling family contains various protein complexes, which regulate gene expression during cellular development and influence DNA damage response in an ATP- and complex-dependent manner, of which details remain elusive. Recent human genome sequencing of various cancer cells revealed frequent mutations in SWI/SNF factors, especially ARID1A, a variant subunit in the BRG1-associated factor (BAF) complex of the SWI/SNF family. We combined live-cell analysis and gene-suppression experiments to show that suppression of either ARID1A or its paralog ARID1B led to reduced nonhomologous end joining activity of DNA double-strand breaks (DSB), decreased accumulation of KU70/KU80 proteins at DSB, and sensitivity to ionizing radiation, as well as to cisplatin and UV. Thus, in contrast to transcriptional regulation, both ARID1 proteins are required for cellular resistance to various types of DNA damage, including DSB. The suppression of other SWI/SNF factors, namely SNF5, BAF60a, BAF60c, BAF155, or BAF170, exhibits a similar phenotype. Of these factors, ARID1A, ARID1B, SNF5, and BAF60c are necessary for the immediate recruitment of the ATPase subunit of the SWI/SNF complex to DSB, arguing that both ARID1 proteins facilitate the damage response of the complex. Finally, we found interdependent protein stability among the SWI/SNF factors, suggesting their direct interaction within the complex and the reason why multiple factors are frequently lost in parallel in cancer cells. Taken together, we show that cancer cells lacking in the expression of certain SWI/SNF factors, including ARID1A, are deficient in DNA repair and potentially vulnerable to DNA damage. ©2014 AACR.

  20. The RFP dynamo: MHD to kinetic regimes

    NASA Astrophysics Data System (ADS)

    Sarff, J. S.; Almagri, A. F.; den Hartog, D. J.; McCollam, K. J.; Nornberg, M. D.; Sauppe, J. P.; Sovinec, C. R.; Terry, P. W.; Triana, J. C.; Brower, D. L.; Ding, W. X.; Parke, E.

    2015-11-01

    The hallmark of magnetic relaxation in an RFP plasma is profile flattening of J0 .B0 /B2 effected by a dynamo-like emf in Ohm's law. This is well-studied in single-fluid MHD, but recent MST results and extended MHD modeling show that both and the Hall emf, - /ene , are important, revealing decoupled electron and ion motion. Since dynamo is current-related, the electron fluid emf, , captures both effects. In MST, the electron flow is dominantly Ve , 1 ~E1 ×B0 /B2 , implying ~ / B . This and the Hall emf are measured in MST for comparison in Ohm's law. A finite-pressure response is also possible, e.g., ``diamagnetic dynamo'', ∇ . /ene , associated with diamagnetic drift, and ``kinetic dynamo'' associated with collisionless streaming of electrons in a stochastic magnetic field. Correlation measurements and using FIR interferometry and Thomson scattering reveal these as small but finite in MST. A kinetic emf might be expected for any high-beta plasma with inhomogeneous pressure. Support by DOE/NSF.

  1. 3D Hall MHD Reconnection Dynamics

    NASA Astrophysics Data System (ADS)

    Huba, J. D.; Rudakov, L.

    2002-05-01

    A 3D Hall MHD simulation code (VooDoo) has recently been developed at the Naval Research Laboratory. We present preliminary results of a fully 3D magnetic reconnection study using this code. The initial configuration of the plasma system is as follows. The ambient, reversed magnetic field is in the x-direction and is proportional to B0 tanh(y/Ly) where Ly is the scale length of the current sheet. Perturbation fields δ Bx and δ By are introduced to initiate the reconnection process. This initial configuration is similar to that used in the 2D GEM reconnection study. However, the perturbation fields are localized in the z-direction. We consider two cases: no guide field (Bz = 0) and a weak guide field (Bz = 0.1B0). We find that the reconnection process is not stationary in the z-direction but propagates in the B x ∇ n direction consistent with Hall drift physics. Hence, an asymmetric disruption of the current sheet ensues. The flow structure of the plasma in the vicinity of the X-point is complex. We find that the `neutral line' (i.e, along the z-direction) is not an ignorable coordinate and is not periodic in Hall MHD reconnection dynamics; two assumptions that are often made in reconnection studies. \\ Research supported by NASA and ONR

  2. Solar wind turbulence: Observations of MHD effects

    NASA Technical Reports Server (NTRS)

    Bavassano, B.

    1995-01-01

    Since the first in-situ observations it was realized that the solar wind is permeated by large-amplitude variations on a very extended range of scales. In this paper an overview of our present state of knowledge for fluctuations in the magnetohydrodynamic (MHD) regime is given. These fluctuations are an important component of the solar wind variability and notably contribute to the overall energy and momentum flux. They generally have a turbulent character and their amplitude is large enough to suggest the presence of nonlinear effects. In recent years the use of high time-resolution data on an extended range of heliocentric distances has allowed major steps towards a satisfactory understanding of the solar wind MHD fluctuations. Their radial evolution in the expanding wind has been determined through detailed analyses of the variations in their spectral features. correlations. and anisotropics. The role of interplanetary sources has been carefully investigated. The influence of interactions with structures convected by the solar wind has been examined. Fluctuations have been studied in the light of theories developed to draw together the effects of both incompressibility and compressibility. Increasing attention has been devoted to the intermittent character of the turbulence. Finally, very recent observations by Ulysses at high heliographic latitudes have allowed the first in-situ analysis of turbulence features in polar regions of the heliosphere.

  3. International Conference on MHD Electrical Power Generation, 7th, Massachusetts Institute of Technology, Cambridge, MA, June 16-20, 1980, Proceedings. Volumes 1, 2 & 3

    NASA Astrophysics Data System (ADS)

    Dawson, A. M.; Overlan, D.

    The first volume of this conference on magnetohydrodynamics (MHD) for electrical power generation covers: (1) MHD pilot plants; (2) MHD generator experiments and modeling; (3) the performance of various MHD generator types; (4) MHD channel design considerations; (5) MHD channel materials considerations; (6) MHD system components, heat recovery and emissions; and (7) MHD oxidizers and inverters. The second volume deals with (8) MHD system magnets and combustors; (9) MHD field, flow and chemical processes; (10) MHD fluid dynamics; (11) MHD electrical power plant design; (12) current transfer and diagnostics; and (13) MHD power plant systems considerations.

  4. Sub-Alfvénic reduced full-f Kinetic MHD equations to study flute like instabilities

    NASA Astrophysics Data System (ADS)

    Sengupta, W.; Hassam, A.; Antonsen, T. M., Jr.

    2016-10-01

    We develop a set of reduced sub-Alfvénic fluid as well as kinetic MHD equations which are suitable for studying flute like instabilities in MHD ordering. The full-f kinetic equations are obtained by reducing Kulsrud's complete set of kinetic MHD system and includes trapped ion dynamics in a toroidal geometry. The nonlinear equations show the presence of Mercier modes, electromagnetic effects, GAMs and Rosenbluth-Hinton zero frequency zonal flows. Linear stability based on our equations shall be compared to the well known Kruskal-Oberman Kinetic MHD stability criteria. In the supersonic limit, for large q, our system can be shown to be equivalent to CGL double adiabatic theory. In the marginal stability limit, we shall discuss trapped particle stabilization of interchange modes. Comparison will also be made to the sub-Alfvénic reduced MHD fluid equations in a large aspect ratio tokamak. We shall show that the trapped particle effects in kinetic theory can be treated as a boundary layer of width the square root of the inverse aspect ratio in phase space. Work supported by DOE.

  5. Singular Currents Near Magnetic Islands in MHD Equilibria: Effects of Pressure Variation Within Flux Surfaces and of Symmetry

    NASA Astrophysics Data System (ADS)

    Reiman, Allan

    2016-10-01

    We present an analytic calculation of the MHD equilibrium current near a magnetic island that includes the effect of the pressure variation on the flux surfaces in that region. The current has logarithmic singularities at the X-lines of magnetic islands in non-stellarator-symmetric equilibria. The singular components vanish in stellarator-symmetric MHD equilibria. (Equilibria invariant under combined reflection in the poloidal and toroidal angles. Tokamaks with balanced double-null divertors are stellarator symmetric, but single-null tokamaks are not.) These equilibrium solutions are to be contrasted with equilibria having B . ∇p = 0 , where the singular components of the pressure-driven currents vanish regardless of the symmetry. They are also to be contrasted with 3D MHD equilibrium solutions that have simply nested flux surfaces, where the pressure-driven current goes like 1 / x near rational surfaces, where x is the distance from the rational surface. (Except in the case of quasi-symmetric flux surfaces.) We work with a closed subset of the MHD equilibrium equations that involves only perpendicular force balance, and is decoupled from parallel force balance. It is not correct to use the parallel component of the conventional MHD force balance equation, B . ∇p = 0 , near magnetic islands. DOE contract DEAC02-76CH03073.

  6. Drift-resistive-inertial ballooning modes in quasihelical stellarators

    SciTech Connect

    Rafiq, T.; Kritz, A. H.; Hegna, C. C.; Callen, J. D.

    2010-02-15

    A linear stability theory of nonideal magnetohydrodynamic (MHD) ballooning modes is investigated using a two fluid model for electron-ion plasmas. Drift-resistive-inertial ballooning mode eigenvalues and eigenfunctions are calculated for a variety of equilibria including axisymmetric shifted circular geometry (s-alpha model) as well as for three dimensional configurations relevant for the Helically Symmetric Stellarator (HSX) [F. S. B. Anderson, A. F. Almagri, D. T. Anderson, et al., Fusion Technology 27, 273 (1995)]. For typical HSX parameters, characteristic ballooning mode growth rates exceed the electron collision frequency. In this regime, electron inertial effects dominate plasma resistivity and produce an instability whose growth rate scales with the electromagnetic skin depth. However, as plasma beta is increased, the resistive and inertial effects become unimportant. Under these conditions, the mode is completely stabilized by drift frequency effects, which dominate resistivity and inertia. Numerical results indicate that in the absence of drift effects, the resistive-inertial MHD modes are purely growing and persist in regimes where ideal MHD ballooning modes are stable. It is found that the magnitudes of the linear growth rates are not sensitive to the addition of a mirror term to the magnetic spectrum that spoils the quasihelical symmetry of the configuration. The eigenvalues and eigenvectors in the strong ballooning approximation are used together with a quasilinear mixing length estimate to determine particle flux and particle diffusivity. The particle diffusivity increases with rising density gradient and collisionality in a plasma with a low electron temperature. This increase in transport is consistent with the increase observed in the edge region of HSX plasmas. The magnitude of the particle diffusivity is computed to be in the range from 5 to 10 m{sup 2}/s, which is consistent with the experimental measured particle diffusivity at the edge of HSX

  7. Multi-drug resistant E.coli urosepsis in physicians following transrectal ultrasound guided prostate biopsies--three cases including one death.

    PubMed

    Carlson, William H; Bell, David G; Lawen, Joseph G; Rendon, Ricardo A

    2010-04-01

    Three male physicians underwent transrectal ultrasound guided prostate biopsies for elevated prostate-specific antigen levels or irregular digital rectal exam findings. All three of these patients developed urosepsis secondary to multi-drug resistant organisms despite antibiotic prophylaxis. There are increasing reports of infectious complications following prostate biopsy caused by multi-drug resistant organisms. These cases highlight the potentially lethal risks to healthcare workers who are more likely to harbor multi-drug resistant organisms than the general population. Further research into preoperative assessment and appropriate antibiotic prophylaxis in all potentially high risk patients is warranted.

  8. Realistic radiative MHD simulation of a solar flare

    NASA Astrophysics Data System (ADS)

    Rempel, Matthias D.; Cheung, Mark; Chintzoglou, Georgios; Chen, Feng; Testa, Paola; Martinez-Sykora, Juan; Sainz Dalda, Alberto; DeRosa, Marc L.; Viktorovna Malanushenko, Anna; Hansteen, Viggo H.; De Pontieu, Bart; Carlsson, Mats; Gudiksen, Boris; McIntosh, Scott W.

    2017-08-01

    We present a recently developed version of the MURaM radiative MHD code that includes coronal physics in terms of optically thin radiative loss and field aligned heat conduction. The code employs the "Boris correction" (semi-relativistic MHD with a reduced speed of light) and a hyperbolic treatment of heat conduction, which allow for efficient simulations of the photosphere/corona system by avoiding the severe time-step constraints arising from Alfven wave propagation and heat conduction. We demonstrate that this approach can be used even in dynamic phases such as a flare. We consider a setup in which a flare is triggered by flux emergence into a pre-existing bipolar active region. After the coronal energy release, efficient transport of energy along field lines leads to the formation of flare ribbons within seconds. In the flare ribbons we find downflows for temperatures lower than ~5 MK and upflows at higher temperatures. The resulting soft X-ray emission shows a fast rise and slow decay, reaching a peak corresponding to a mid C-class flare. The post reconnection energy release in the corona leads to average particle energies reaching 50 keV (500 MK under the assumption of a thermal plasma). We show that hard X-ray emission from the corona computed under the assumption of thermal bremsstrahlung can produce a power-law spectrum due to the multi-thermal nature of the plasma. The electron energy flux into the flare ribbons (classic heat conduction with free streaming limit) is highly inhomogeneous and reaches peak values of about 3x1011 erg/cm2/s in a small fraction of the ribbons, indicating regions that could potentially produce hard X-ray footpoint sources. We demonstrate that these findings are robust by comparing simulations computed with different values of the saturation heat flux as well as the "reduced speed of light".

  9. Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the Prague-15 study.

    PubMed

    Rosa, Ján; Widimský, Petr; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Waldauf, Petr; Bednář, František; Zelinka, Tomáš; Holaj, Robert; Štrauch, Branislav; Šomlóová, Zuzana; Táborský, Miloš; Václavík, Jan; Kociánová, Eva; Branny, Marian; Nykl, Igor; Jiravský, Otakar; Widimský, Jiří

    2015-02-01

    This prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-based renal denervation (Symplicity, Medtronic) versus intensified pharmacological treatment including spironolactone (if tolerated) in patients with true-resistant hypertension. This was confirmed by 24-hour ambulatory blood pressure monitoring after excluding secondary hypertension and confirmation of adherence to therapy by measurement of plasma antihypertensive drug levels before enrollment. One-hundred six patients were randomized to renal denervation (n=52), or intensified pharmacological treatment (n=54) with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. A significant reduction in 24-hour average systolic blood pressure after 6 months (-8.6 [95% cofidence interval: -11.8, -5.3] mm Hg; P<0.001 in renal denervation versus -8.1 [95% cofidence interval: -12.7, -3.4] mm Hg; P=0.001 in pharmacological group) was observed, which was comparable in both groups. Similarly, a significant reduction in systolic office blood pressure (-12.4 [95% cofidence interval: -17.0, -7.8] mm Hg; P<0.001 in renal denervation versus -14.3 [95% cofidence interval: -19.7, -8.9] mm Hg; P<0.001 in pharmacological group) was present. Between-group differences in change were not significant. The average number of antihypertensive drugs used after 6 months was significantly higher in the pharmacological group (+0.3 drugs; P<0.001). A significant increase in serum creatinine and a parallel decrease of creatinine clearance were observed in the pharmacological group; between-group difference were borderline significant. The 6-month results of this study confirmed the safety of renal denervation. In conclusion, renal denervation achieved reduction of blood pressure comparable with intensified pharmacotherapy. © 2014 American Heart Association, Inc.

  10. Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes.

    PubMed Central

    Misra, T K; Brown, N L; Fritzinger, D C; Pridmore, R D; Barnes, W M; Haberstroh, L; Silver, S

    1984-01-01

    The mercuric ion-resistance operons of plasmid R100 (originally from Shigella) and transposon Tn501 (originally from a plasmid isolated in Pseudomonas) have been compared by DNA sequence analysis. The sequences for the first 1340 base pairs of Tn501 are given with the best alignment with the comparable 1319 base pairs of R100. The homology between the two sequences starts at base 58 after the end of the insertion sequence IS-1 of R100. The sequences include the transcriptional regulatory region, and the homology is particularly strong in regions just upstream from potential transcriptional initiation sites. The trans-acting regulatory gene merR consists of 180 base pairs in both cases and codes for a highly basic polypeptide of 60 amino acids, which is also rich in serine. The Tn501 and R100 merR genes differ in 25 of the 180 base positions, and the resulting polypeptides differ in seven amino acids. The regulatory region before the major transcription initiation site contains potential -35 and -10 sequences and dyad symmetrical sequences, which may be the merR binding sites for transcriptional regulation. The first structural gene, merT, encodes a highly hydrophobic polypeptide of 116 amino acids. The R100 and Tn501 merT genes differ in 17% of their positions, leading to 14 (12%) amino acid changes. This region had previously been shown to encode a protein governing membrane transport of mercuric ions. The second structural gene, merC, would give a 91 amino acid polypeptide with a hydrophobic amino-terminal segment. The Tn501 and R100 merC genes differ at 37 base positions, leading to 10 amino acid changes. PMID:6091128

  11. Control of Multidrug-Resistant Pseudomonas aeruginosa in Allogeneic Hematopoietic Stem Cell Transplant Recipients by a Novel Bundle Including Remodeling of Sanitary and Water Supply Systems.

    PubMed

    Kossow, Annelene; Kampmeier, Stefanie; Willems, Stefanie; Berdel, Wolfgang E; Groll, Andreas H; Burckhardt, Birgit; Claudia, Rossig; Groth, Christoph; Idelevich, Evgeny A; Kipp, Frank; Mellmann, Alexander; Stelljes, Matthias

    2017-09-15

    Infections by multidrug-resistant Pseudomonas aeruginosa (MDRPa) are an important cause of morbidity and mortality in patients after allogeneic hematopoietic stem cell transplantation (HSCT). Humid environments can serve as a reservoir and source of infection by this pathogen. To minimize the risk of infection from these reservoirs, we performed extensive remodeling of sanitation and water installations as the focus of our hygiene bundle. During the reconstruction of our transplantation unit (April 2011-April 2014) we implemented several technical modifications to reduce environmental contamination by and subsequent spreading of MDRPa, including a newly designed shower drain, disinfecting siphons underneath the sinks, and rimless toilets. During a 3-year study period (2012-2014), we tracked the number of patients affected by MDRPa (colonized and/or infected) and the outcome of infected patients, and monitored the environmental occurrence of this pathogen. We further performed whole-genome sequencing of nosocomial MDRPa strains to evaluate genotypic relationships between isolates. Whereas 31 (9.2%; 18 colonized, 13 infected) patients were affected in 2012 and 2013, the number decreased to 3 in 2014 (17%; 3 colonized, 0 infected). Lethality by MDRPa similarly decreased from 3.6% to 0%. Environmental detection of MDRPa decreased in toilets from 18.9% in 2012-2013 to 6.1% in the following year and from 8.1% to 3.0%, respectively, in shower outlets. Whole-genome sequencing showed close relationships between environmental and patient-derived isolates. Hospital construction measures aimed at controlling environmental contamination by and spread of MDRPa are effective at minimizing the risk of highly lethal MDRPa infections.

  12. Flow-Induced New Channels of Energy Exchange in Multi-Scale Plasma Dynamics - Revisiting Perturbative Hybrid Kinetic-MHD Theory.

    PubMed

    Shiraishi, Junya; Miyato, Naoaki; Matsunaga, Go

    2016-05-10

    It is found that new channels of energy exchange between macro- and microscopic dynamics exist in plasmas. They are induced by macroscopic plasma flow. This finding is based on the kinetic-magnetohydrodynamic (MHD) theory, which analyses interaction between macroscopic (MHD-scale) motion and microscopic (particle-scale) dynamics. The kinetic-MHD theory is extended to include effects of macroscopic plasma flow self-consistently. The extension is realised by generalising an energy exchange term due to wave-particle resonance, denoted by δ WK. The first extension is generalisation of the particle's Lagrangian, and the second one stems from modification to the particle distribution function due to flow. These extensions lead to a generalised expression of δ WK, which affects the MHD stability of plasmas.

  13. Flow-Induced New Channels of Energy Exchange in Multi-Scale Plasma Dynamics – Revisiting Perturbative Hybrid Kinetic-MHD Theory

    PubMed Central

    Shiraishi, Junya; Miyato, Naoaki; Matsunaga, Go

    2016-01-01

    It is found that new channels of energy exchange between macro- and microscopic dynamics exist in plasmas. They are induced by macroscopic plasma flow. This finding is based on the kinetic-magnetohydrodynamic (MHD) theory, which analyses interaction between macroscopic (MHD-scale) motion and microscopic (particle-scale) dynamics. The kinetic-MHD theory is extended to include effects of macroscopic plasma flow self-consistently. The extension is realised by generalising an energy exchange term due to wave-particle resonance, denoted by δ WK. The first extension is generalisation of the particle’s Lagrangian, and the second one stems from modification to the particle distribution function due to flow. These extensions lead to a generalised expression of δ WK, which affects the MHD stability of plasmas. PMID:27160346

  14. Multifluid MHD Simulations of the Plasma Environment of Comet Churyumov-Gerasimenko at Different Heliocentric Distances

    NASA Astrophysics Data System (ADS)

    Huang, Z.; Jia, X.; Rubin, M.; Fougere, N.; Gombosi, T. I.; Tenishev, V.; Combi, M. R.; Bieler, A. M.; Toth, G.; Hansen, K. C.; Shou, Y.

    2014-12-01

    We study the plasma environment of the comet Churyumov-Gerasimenko, which is the target of the Rosetta mission, by performing large scale numerical simulations. Our model is based on BATS-R-US within the Space Weather Modeling Framework that solves the governing multifluid MHD equations, which describe the behavior of the cometary heavy ions, the solar wind protons, and electrons. The model includes various mass loading processes, including ionization, charge exchange, dissociative ion-electron recombination, as well as collisional interactions between different fluids. The neutral background used in our MHD simulations is provided by a kinetic Direct Simulation Monte Carlo (DSMC) model. We will simulate how the cometary plasma environment changes at different heliocentric distances.

  15. Design and calculated performance and cost of the ECAS Phase II open cycle MHD power generation system

    NASA Technical Reports Server (NTRS)

    Harris, L. P.

    1977-01-01

    A 2000 MWe MHD/steam plant for central station applications has been designed and costed as part of the Energy Conversion Alternatives Study (ECAS). This plant is fueled by Illinois No. 6 coal, rejects heat through mechanical draft wet cooling towers, and includes coal processing equipment, seed reprocessing, electrical inversion of the MHD generator output and emission controls to current EPA standards. It yields an estimated overall efficiency of 0.483 (7066 Btu/kWe-hr), a capital cost of $718 per kWe (1975 dollars), and a cost of electricity at 65% capacity factor of 32 mills per kWe-hr. If the assumed life and reliability could be achieved with these performance parameters, the MHD system should prove attractive.

  16. MHD seawater thruster performance: A comparison of predictions with experimental results from a two Tesla test facility

    SciTech Connect

    Picologlou, B. F.; Doss, E. D.; Geyer, H. K.; Sikes, W. C.; Ranellone, R. F.

    1992-01-01

    A two Tesla test facility was designed, built, and operated to investigate the performance of magnetohydrodynamic (MHD) seawater thrusters. The results of this investigation are used to validate a design oriented MHD thruster performance computer code. The thruster performance code consists of a one-dimensional MHD hydrodynamic model coupled to a two-dimensional electrical model. The code includes major loss mechanisms affecting the performance of the thruster. Among these losses are the joule dissipation losses, frictional losses, electrical end losses, and single electrode potential losses. The facility test loop, its components, and their design are presented in detail. Additionally, the test matrix and its rationale are discussed. Representative experimental results of the test program are presented, and are compared to pretest computer model predictions. Good agreement between predicted and measured data has served to validate the thruster performance computer models.

  17. MHD Augmentation of Rocket Engines Using Beamed Energy

    NASA Astrophysics Data System (ADS)

    Lineberry, John T.; Chapman, James N.; Litchford, Ron J.; Jones, Jonathan

    2003-05-01

    MHD technology and fundamental relations that pertain to accelerating a working fluid for propulsion of space vehicles are reviewed. Previous concepts on MHD propulsion have considered use of an on-board power supply to provide the electric power for the MHD thruster which is accompanied by an obvious weight penalty. In this study, an orbiting power station that beams microwave or laser power to the spacecraft is considered which eliminates this penalty making the thruster significantly more effective from the thrust-to-weight viewpoint. The objective of the study was to investigate augmenting a rocket motor to increase the ISP into the 2,500 seconds range using MHD acceleration. Mission scenarios are presented to parametrically compare the MHD augmented motor. Accelerator performance is calculated for an array of cases which vary the mass throughput, magnetic field strength and MHD interaction level. Performance improved with size, magnetic field strength and interaction level, although lower interaction levels can also produce attractive configurations. Accelerator efficiencies are typically 80-90%. The results display a large regime for improved performance in which the extent of the regime is critically dependent upon the weight of the power receiving equipment (rectenna). It is concluded that this system has potential when used with an orbiting power station that transmits power to the space vehicle by microwave radiation or laser beams. The most critical technology improvement needed is a reduced weight rectenna system but more development is also needed on the MHD accelerator, which is currently underway with NASA sponsorship.

  18. Revisiting MHD stability comparison theorems: Some surprising new results

    NASA Astrophysics Data System (ADS)

    Cerfon, Antoine; Freidberg, Jeffrey

    2009-05-01

    The classic MHD stability comparison theorems (Kruskal-Oberman, Rosenbluth-Rostoker) show that ideal MHD yields the most stringent stability limits according to the hierarchy δWCGL>δWKIN>δWMHD. This has long justified the use of ideal MHD for conservative predictions of MHD stability boundaries. We reexamine these theorems, with the following conclusions:(1) It is crucial to distinguish between ergodic and closed field line systems.(2) It is essential to account for resonant particles in the kinetic MHD model.(3) For ergodic systems the original kinetic MHD analysis over-estimates stability: δWKIN>δWMHD. Our new result predicts δWKIN=δWMHD.(4) For closed line systems plasma compressibility effects become important, and resonant particle effects vanish. Both the original and new analysis predict δWKIN>δWMHD. However, using a Vlasov-Fluid model with Vlasov ions and fluid electrons we show that both δWKIN and δWMHD, while mathematically correct, yield the wrong physical result. The V-F model shows that at marginal stability the compressibility stabilization term vanishes identically! For ergodic systems, marginal stability is always incompressible, so δWKIN=δWMHD=δWVF. For compressible modes in closed line systems, however, perpendicular resonant particle effects cancel the stabilizing effect of plasma compressibility predicted by ideal and kinetic MHD: δWKIN>δWMHD>δWVF.

  19. MHD performance demonstration experiment, FY 1974 to FY 1984

    NASA Astrophysics Data System (ADS)

    Whitehead, G. L.; Christensen, L. S.; Felderman, R. J.

    1984-06-01

    A national program for the development of commercial, open-cycle, magnetohydrodynamic (MHD) power generation is described. The emphasis of that national program was, and is, on establishing the engineering feasibilty of using coal to fuel the MHD power system. In order to establish feasibility it was necessary to experimentally demonstrate that an MHD generator system simulating a commercial-sized device can convert 16 to 18% of the available thermal energy into electric power at an isentropic efficiency of 60 to 70%. A presidential decree encouraged any government agency which might possess an organic MHD capability to assist ERDA in formulating and executing the national program. Since the largest MHD facility in the United States was located at the Arnold Engineering Development Center (AEDC), it was selected to be the national program element to demonstrate performance. As a result, the AEDC has been under contract since December 1973 (first to ERDA, later to its successor, the department of Energy, DOE) to modify existing equipment and to design, fabricate, and install new hardware to perform the MHD Performance Demonstration Experiment. The MHD facility is described and all results achieved to date are summarized.

  20. Effect of fast electrons on the stability of resistive interchange modes in the TJ-II stellarator

    NASA Astrophysics Data System (ADS)

    García, L.; Ochando, M. A.; Carreras, B. A.; Carralero, D.; Hidalgo, C.; van Milligen, B. Ph.

    2016-06-01

    In this paper, we report on electromagnetic phenomena in low-β plasmas at the TJ-II stellarator, controlled by external heating. To understand the observations qualitatively, we introduce a simple modification of the standard resistive MHD equations, to include the potential impact of fast electrons on instabilities. The dominant instabilities of the modeling regime are resistive interchange modes, and calculations are performed in a configuration with similar characteristics as the TJ-II stellarator. The main effect of the trapping of fast electrons by magnetic islands induced by MHD instabilities is to increase the magnetic component of the fluctuations, changing the character of the instability to tearing-like and modifying the frequency of the modes. These effects seem to be consistent with some of the experimental observations.

  1. Test Particle Simulation of Acceleration in Cascading Current Sheet Obtained with 2.5D AMR MHD

    NASA Astrophysics Data System (ADS)

    Liu, Siming; Büchner, Jörg; Gan, Weiqun; Bárta, Miroslav; Zhou, Xiaowei

    2016-07-01

    With electro-magnetic field configuration derived from 2.5D AMR MHD simulations, we calculate the orbit of test charged particles with the guiding center approximation and study the particle acceleration by the induction and resistive electric fields. The induction field can lead to gradual acceleration via the drift of the particle guiding center in magnetic field curvature or gradient.The resistive electric field can lead to run away acceleration with particle energy changing drastically in regions with anomalous resistivity. We will discuss the implication of these results on the study of particle acceleration in turbulent reconnection current sheets.

  2. A MHD-turbulence model for solar corona

    NASA Astrophysics Data System (ADS)

    Romeou, Z.; Velli, M.; Einaudi, G.

    2009-02-01

    The disposition of energy in the solar corona has always been a problem of great interest. It remains an open question how the low temperature photosphere supports the occurence of solar extreme phenomena. In this work, a turbulent heating mechanism for the solar corona through the framework of reduced magnetohydrodynamics (RMHD) is proposed. Two-dimensional incompressible long time simulations of the average energy disposition have been carried out with the aim to reveal the characteristics of the long time statistical behavior of a two-dimensional cross-section of a coronal loop and the importance of the photospheric time scales in the understanding of the underlying mechanisms. It was found that for a slow, shear type photospheric driving the magnetic field in the loop self-organizes at large scales via an inverse MHD cascade. The system undergoes three distinct evolutionary phases. The initial forcing conditions are quickly “forgotten” giving way to an inverse cascade accompanied with and ending up to electric current dissipation. Scaling laws are being proposed in order to quantify the nonlinearity of the system response which seems to become more impulsive for decreasing resistivity. It is also shown that few, if any, qualitative changes in the above results occur by increasing spatial resolution.

  3. Power take-off analysis for diagonally connected MHD channels

    SciTech Connect

    Pan, Y C; Doss, E D

    1980-01-01

    The electrical loading of the power take-off region of diagonally connected MHD channels is investigated by a two-dimensional model. The study examines the loading schemes typical of those proposed for the U-25 and U-25 Bypass channels. The model is applicable for the following four cases: (1) connection with diodes only, (2) connection with diodes and equal resistors, (3) connection with diodes and variable resistances to obtain a given current distribution, and (4) connection with diodes and variable resistors under changing load. The analysis is applicable for the power take-off regions of single or multiple-output systems. The general behaviors of the current and the potential distributions in all four cases are discussed. The analytical results are in good agreement with the experimental data. It is found possible to design the electrical circuit of the channel in the take-off region so as to achieve a fairly even load current output under changing total load current.

  4. Detection of vancomycin-resistant enterococci from faecal samples of Iberian wolf and Iberian lynx, including Enterococcus faecium strains of CC17 and the new singleton ST573.

    PubMed

    Gonçalves, Alexandre; Igrejas, Gilberto; Radhouani, Hajer; López, María; Guerra, Ana; Petrucci-Fonseca, Francisco; Alcaide, Eva; Zorrilla, Irene; Serra, Rodrigo; Torres, Carmen; Poeta, Patrícia

    2011-12-01

    The aim of this study was to perform the molecular characterization of vancomycin resistant enterococci (VRE) within the faecal flora of Iberian wolf and Iberian lynx. The association with other resistance genes and the detection of virulence genes were also analysed. From 2008 to 2010, 365 faecal samples from Iberian wolf and Iberian lynx were collected and tested for VRE recovery. Mechanisms of resistance to vancomycin and other antibiotics, as well as genes encoding virulence factors were detected through PCR. Multilocus Sequence Typing (MLST) was performed for Enterococcus faecium strains. VRE were recovered in 8 of the 365 analysed samples. The vanA gene was identified in two E. faecium isolates recovered from Iberian wolf faecal samples and the remaining six showed intrinsic resistance (3 vanC1-E. gallinarum and 3 vanC2-E. casseliflavus, from Iberian wolf and Iberian lynx faecal samples, respectively). One vanA-containing isolate showed tetracycline and erythromycin resistance [with erm(B) and tet(L) genes] and the other one also exhibited ampicillin and kanamycin resistance [with erm(B), tet(M) and aph(3')-III genes]. One of the vanA-isolates revealed a new sequence type named ST573 and the other one belonged to the CC17 clonal complex (ST18). The hyl gene was detected in one E. casseliflavus and three E. gallinarum but not among vanA-positive isolates, and the occurrence of cylA and cylL genes was confirmed in two E. casseliflavus isolates. A low prevalence of VRE has been detected in faecal samples of Iberian wolf and Iberian lynx and strains with an acquired mechanism of resistance to vancomycin have not been detected among Iberian lynx.

  5. Effect of intradialytic resistance band exercise on physical function in patients on maintenance hemodialysis: a pilot study.

    PubMed

    Bullani, Roberto; El-Housseini, Youssef; Giordano, Fabrice; Larcinese, Anna; Ciutto, Lorella; Bertrand, Pauline Coti; Wuerzner, Grégoire; Burnier, Michel; Teta, Daniel

    2011-01-01

    Although physical activity is recommended in patients on maintenance hemodialysis (MHD), randomized controlled trials testing the effects of exercise in this population have given conflicting results. In general, aerobic exercises mostly failed to produce improvements in physical function, whereas resistance exercises, although less studied, appeared to be more promising. The use of sophisticated materials such as leg press and free weights may preclude widespread application of resistance training in patients on MHD. Simple and cheap elastic bands may thus be an attractive alternative. We tested the feasibility of a supervised intradialytic resistance band exercise training program, and its effects on physical function, in patients on MHD. A total of 11 unselected adult patients on MHD from our center, aged 70 ± 10.7 (mean ± standard deviation) years, including 8 men and 3 women, accepted to follow the program under the supervision of qualified physiotherapists. Thirty-six exercise sessions of moderate intensity (twice a week, mean duration 40 minutes each, during 4.5 to 6 months), mainly involving leg muscles against an elastic resistance, were performed. The exercise program was well tolerated and all patients completed it. Statistically significant improvements were observed in the following tests: Tinetti test, 23.9 ± 3.9 points before versus 25.7 ± 3.5 points after the program (P = .022); the Timed Up and Go test, 12.1 ± 6.6 versus 10 ± 5.8 seconds (P = .0156). Improvements in the 6-minute walk distance and in the one-leg balance tests just failed to reach statistical significance. In this single-center pilot study, an intradialytic resistance band exercise program was feasible, well tolerated, and showed encouraging results on physical function.

  6. Suppression of MHD fluctuations leading to improved confinement in a gun-driven spheromak.

    PubMed

    McLean, H S; Woodruff, S; Hooper, E B; Bulmer, R H; Hill, D N; Holcomb, C; Moller, J; Stallard, B W; Wood, R D; Wang, Z

    2002-03-25

    Magnetic fluctuations have been reduced to approximately 1% during discharges on the Sustained Spheromak Physics Experiment by shaping the spatial distribution of the bias magnetic flux in the device. In the resulting quiescent regime, the safety factor profile is nearly flat in the plasma and the dominant ideal and resistive MHD modes are greatly reduced. During this period, the temperature profile is peaked at the magnetic axis and maps onto magnetic flux contours. Energy confinement time is improved over previous reports in a driven spheromak.

  7. Movement of IS26-associated antibiotic resistance genes occurs via a translocatable unit that includes a single IS26 and preferentially inserts adjacent to another IS26.

    PubMed

    Harmer, Christopher J; Moran, Robert A; Hall, Ruth M

    2014-10-07

    The insertion sequence IS26 plays a key role in disseminating antibiotic resistance genes in Gram-negative bacteria, forming regions containing more than one antibiotic resistance gene that are flanked by and interspersed with copies of IS26. A model presented for a second mode of IS26 movement that explains the structure of these regions involves a translocatable unit consisting of a unique DNA segment carrying an antibiotic resistance (or other) gene and a single IS copy. Structures resembling class I transposons are generated via RecA-independent incorporation of a translocatable unit next to a second IS26 such that the ISs are in direct orientation. Repeating this process would lead to arrays of resistance genes with directly oriented copies of IS26 at each end and between each unique segment. This model requires that IS26 recognizes another IS26 as a target, and in transposition experiments, the frequency of cointegrate formation was 60-fold higher when the target plasmid contained IS26. This reaction was conservative, with no additional IS26 or target site duplication generated, and orientation specific as the IS26s in the cointegrates were always in the same orientation. Consequently, the cointegrates were identical to those formed via the known mode of IS26 movement when a target IS26 was not present. Intact transposase genes in both IS26s were required for high-frequency cointegrate formation as inactivation of either one reduced the frequency 30-fold. However, the IS26 target specificity was retained. Conversion of each residue in the DDE motif of the Tnp26 transposase also reduced the cointegration frequency. Importance: Resistance to antibiotics belonging to several of the different classes used to treat infections is a critical problem. Multiply antibiotic-resistant bacteria usually carry large regions containing several antibiotic resistance genes, and in Gram-negative bacteria, IS26 is often seen in these clusters. A model to explain the unusual

  8. Broken Symmetry and Coherent Structure in MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.

    2007-01-01

    Absolute equilibrium ensemble theory for ideal homogeneous magnetohydrodynamic (MHD) turbulence is fairly well developed. Theory and Simulation indicate that ideal MHD turbulence non-ergodic and contains coherent structure. The question of applicability real (i.e., dissipative) MHD turbulence is examined. Results from several very long time numerical simulations on a 64(exp 3) grid are presented. It is seen that coherent structure begins to form before decay dominates over nonlinearity. The connection with inverse spectral cascades and selective decay will also be discussed.

  9. A summary of the ECAS MHD power plant results

    NASA Technical Reports Server (NTRS)

    Seikel, G. R.; Harris, L. P.

    1976-01-01

    The performance and the cost of electricity (COE) for MHD systems utilizing coal or coal derived fuels are summarized along with a conceptual open cycle MHD plant design. The results show that open cycle coal fired recuperatively preheated MHD systems have potentially one of the highest coal-pile-to-bus bar efficiencies (48.3%) and also one of the lowest COE of the systems studied. Closed cycle, inert gas systems do not appear to have the potential of exceeding the efficiency of or competing with the COE of advanced steam plants.

  10. MHD instabilities in accretion mounds - I. 2D axisymmetric simulations

    NASA Astrophysics Data System (ADS)

    Mukherjee, Dipanjan; Bhattacharya, Dipankar; Mignone, Andrea

    2013-04-01

    We have performed stability analysis of axisymmetric accretion mounds on neutron stars in high-mass X-ray binaries by 2D magnetohydrodynamic (MHD) simulations with the PLUTO MHD code. We find that the mounds are stable with respect to interchange instabilities, but the addition of excess mass destabilizes the equilibria. Our simulations confirm that accretion mounds are unstable with respect to MHD instabilities beyond a threshold mass. We investigate both filled and hollow mounds and for the latter also compute the expected profile of cyclotron resonance scattering features (CRSF). In comparison to the CRSF from filled mounds reported in our earlier work, hollow mounds display wider and more complex line profiles.

  11. Emerging importance of mismatch repair components including UvrD helicase and their cross-talk with the development of drug resistance in malaria parasite.

    PubMed

    Ahmad, Moaz; Tuteja, Renu

    2014-12-01

    Human malaria is an important parasitic infection responsible for a significant number of deaths worldwide, particularly in tropical and subtropical regions. The recent scenario has worsened mainly because of the emergence of drug-resistant malaria parasites having the potential to spread across the world. Drug-resistant parasites possess a defective mismatch repair (MMR); therefore, it is essential to explore its mechanism in detail to determine the underlying cause. Recently, artemisinin-resistant parasites have been reported to exhibit nonsynonymous single nucleotide polymorphisms in genes involved in MMR pathways such as MutL homolog (MLH) and UvrD. Plasmodium falciparum MLH is an endonuclease required to restore the defective MMR in drug-resistant W2 strain of P. falciparum. Although the role of helicases in eukaryotic MMR has been questioned, the identification and characterization of the UvrD helicase and their cross-talk with MLH in P. falciparum suggests the possible involvement of UvrD in MMR. A comparative genome-wide analysis revealed the presence of the UvrD helicase in Plasmodium species, while it is absent in human host. Therefore, PfUvrD may emerge as a suitable drug target to control malaria. This review study is focused on recent developments in MMR biochemistry, emerging importance of the UvrD helicase, possibility of its involvement in MMR and the emerging cross-talk between MMR components and drug resistance in malaria parasite. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Incidence, Antimicrobial Resistance, and Molecular Characteristics of Nontyphoidal Salmonella Including Extended-Spectrum β-Lactamase Producers in Retail Chicken Meat.

    PubMed

    Choi, Dasom; Chon, Jung-Whan; Kim, Hong-Seok; Kim, Dong-Hyeon; Lim, Jong-Soo; Yim, Jin-Hyeok; Seo, Kun-Ho

    2015-11-01

    The present study was undertaken to determine the prevalence of Salmonella in 100 chicken carcass samples from five integrated broiler operation brands in Korea. Serotypes, antibiotic resistance patterns, extended-spectrum β-lactamase (ESBL) genotype, and clonal divergence using multilocus sequence typing of the isolated strains were analyzed. A total of 42 chicken samples were contaminated with nontyphoidal Salmonella (NTS) isolates: 16 isolates (38%) were Salmonella Virchow, 9 (21%) were Salmonella Bareilly, and 8 (19%) were Salmonella Infantis. A multidrug resistance (MDR; resistant to more than three classes of antibiotics) phenotype was observed in 29% of the isolates, which were resistant to five or more classes of antibiotics. The dominant MDR type was resistance to classes of penicillin, cephalosporins, aminoglycosides, quinolones, and tetracyclines. All the MDR isolates were positive for ESBL producers, and all but one (with the CTX-M-1 genotype) had the CTX-M-15 genotype. Multilocus sequence typing of the isolates revealed ST16 as the dominant sequence type; Salmonella Virchow, Salmonella Infantis, and Salmonella Richmond were all ST16, indicating a close genetic relationship between these serovars. This is the first study in Korea showing the CTX-M-1 type of NTS and the prevalence of ESBL-producing strains among NTS isolated from retail chicken meat. Our findings suggest that MDR Salmonella contamination is widely prevalent in retail chicken meat, and consumption of inadequately cooked products could lead to dissemination of NTS, which is hazardous to human health.

  13. Numerical linearized MHD model of flapping oscillations

    NASA Astrophysics Data System (ADS)

    Korovinskiy, D. B.; Ivanov, I. B.; Semenov, V. S.; Erkaev, N. V.; Kiehas, S. A.

    2016-06-01

    Kink-like magnetotail flapping oscillations in a Harris-like current sheet with earthward growing normal magnetic field component Bz are studied by means of time-dependent 2D linearized MHD numerical simulations. The dispersion relation and two-dimensional eigenfunctions are obtained. The results are compared with analytical estimates of the double-gradient model, which are found to be reliable for configurations with small Bz up to values ˜ 0.05 of the lobe magnetic field. Coupled with previous results, present simulations confirm that the earthward/tailward growth direction of the Bz component acts as a switch between stable/unstable regimes of the flapping mode, while the mode dispersion curve is the same in both cases. It is confirmed that flapping oscillations may be triggered by a simple Gaussian initial perturbation of the Vz velocity.

  14. A helically distorted MHD flux rope model

    NASA Technical Reports Server (NTRS)

    Theobald, Michael L.; Montgomery, David

    1990-01-01

    A flux rope model is proposed which has a variable degree of helical distortion from axisymmetry. The basis for this suggestion is a series of numerical and analytical investigations of magnetohydrodynamic states which result when an axial electric current is directed down on dc magnetic field. The helically distorted states involve a flow velocity and seem to be favored because of their lower rate of energy dissipation. Emphasis is on the magnetometer and particle energy analyzer traces that might be characteristic of such flux ropes. It is shown that even a fractionally small helical distortion may considerably alter the traces in minimum-variance coordinates. In short, what may be fairly common MHD processes can render a flux rope almost unrecognizable under standard diagnostics, even if the departures from axisymmetry are not great.

  15. Global MHD Models of the Solar Corona

    NASA Technical Reports Server (NTRS)

    Suess, S. T.; Rose, Franklin (Technical Monitor)

    2001-01-01

    Global magnetohydrodynamic (MHD) models of the solar corona are computationally intensive, numerically complex simulations that have produced important new results over the past few years. After a brief overview of how these models usually work, I will address three topics: (1) How these models are now routinely used to predict the morphology of the corona and analyze Earth and space-based remote observations of the Sun; (2) The direct application of these models to the analysis of physical processes in the corona and chromosphere and to the interpretation of in situ solar wind observations; and (3) The use of results from global models to validate the approximations used to make detailed studies of physical processes in the corona that are not otherwise possible using the global models themselves.

  16. Multimegawatt NEP with vapor core reactor MHD

    NASA Astrophysics Data System (ADS)

    Smith, Blair; Knight, Travis; Anghaie, Samim

    2002-01-01

    Efforts at the Innovative Nuclear Space Power and Propulsion Institute have assessed the feasibility of combining gaseous or vapor core reactors with magnetohydrodynamic power generators to provide extremely high quality, high density, and low specific mass electrical power for space applications. Innovative shielding strategies are employed to maintain an effective but relatively low mass shield, which is the most dominating part of multi-megawatt space power systems. The fission driven magnetohydrodynamic generator produces tens of kilowatt DC power at specific mass of less than 0.5 kg/kW for the total power system. The MHD output with minor conditioning is coupled to magnetoplasmadynamic thruster to achieve an overall NEP system specific mass of less than 1.0 kg/kW for power levels above 20 MWe. Few other concepts would allow comparable ensuing payload savings and flexible mission abort options for manned flights to Mars for example. .

  17. MHD simulation of the Bastille day event

    SciTech Connect

    Linker, Jon Torok, Tibor; Downs, Cooper; Lionello, Roberto; Titov, Viacheslav; Caplan, Ronald M.; Mikić, Zoran; Riley, Pete

    2016-03-25

    We describe a time-dependent, thermodynamic, three-dimensional MHD simulation of the July 14, 2000 coronal mass ejection (CME) and flare. The simulation starts with a background corona developed using an MDI-derived magnetic map for the boundary condition. Flux ropes using the modified Titov-Demoulin (TDm) model are used to energize the pre-event active region, which is then destabilized by photospheric flows that cancel flux near the polarity inversion line. More than 10{sup 33} ergs are impulsively released in the simulated eruption, driving a CME at 1500 km/s, close to the observed speed of 1700km/s. The post-flare emission in the simulation is morphologically similar to the observed post-flare loops. The resulting flux rope that propagates to 1 AU is similar in character to the flux rope observed at 1 AU, but the simulated ICME center passes 15° north of Earth.

  18. Drag reduction in turbulent MHD pipe flows

    NASA Technical Reports Server (NTRS)

    Orlandi, P.

    1996-01-01

    This is a preliminary study devoted to verifying whether or not direct simulations of turbulent Magneto-Hydro-Dynamic (MHD) flows in liquid metals reproduce experimental observations of drag reduction. Two different cases have been simulated by a finite difference scheme which is second order accurate in space and time. In the first case, an external azimuthal magnetic field is imposed. In this case, the magnetic field acts on the mean axial velocity and complete laminarization of the flow at N(sub a) = 30 has been achieved. In the second case, an axial magnetic field is imposed which affects only fluctuating velocities, and thus the action is less efficient. This second case is more practical, but comparison between numerical and experimental results is only qualitative.

  19. General Relativistic MHD Simulations of Jet Formation

    NASA Technical Reports Server (NTRS)

    Mizuno, Y.; Nishikawa, K.-I.; Hardee, P.; Koide, S.; Fishman, G. J.

    2005-01-01

    We have performed 3-dimensional general relativistic magnetohydrodynamic (GRMHD) simulations of jet formation from an accretion disk with/without initial perturbation around a rotating black hole. We input a sinusoidal perturbation (m = 5 mode) in the rotation velocity of the accretion disk. The simulation results show the formation of a relativistic jet from the accretion disk. Although the initial perturbation becomes weakened by the coupling among different modes, it survives and triggers lower modes. As a result, complex non-axisymmetric density structure develops in the disk and the jet. Newtonian MHD simulations of jet formation with a non-axisymmetric mode show the growth of the m = 2 mode but GRMHD simulations cannot see the clear growth of the m = 2 mode.

  20. MHD simulation of the Bastille day event

    NASA Astrophysics Data System (ADS)

    Linker, Jon; Torok, Tibor; Downs, Cooper; Lionello, Roberto; Titov, Viacheslav; Caplan, Ronald M.; Mikić, Zoran; Riley, Pete

    2016-03-01

    We describe a time-dependent, thermodynamic, three-dimensional MHD simulation of the July 14, 2000 coronal mass ejection (CME) and flare. The simulation starts with a background corona developed using an MDI-derived magnetic map for the boundary condition. Flux ropes using the modified Titov-Demoulin (TDm) model are used to energize the pre-event active region, which is then destabilized by photospheric flows that cancel flux near the polarity inversion line. More than 1033 ergs are impulsively released in the simulated eruption, driving a CME at 1500 km/s, close to the observed speed of 1700km/s. The post-flare emission in the simulation is morphologically similar to the observed post-flare loops. The resulting flux rope that propagates to 1 AU is similar in character to the flux rope observed at 1 AU, but the simulated ICME center passes 15° north of Earth.