Open-field behavior of house mice selectively bred for high voluntary wheel-running.

PubMed

Bronikowski, A M; Carter, P A; Swallow, J G; Girard, I A; Rhodes, J S; Garland, T

2001-05-01

Open-field behavioral assays are commonly used to test both locomotor activity and emotionality in rodents. We performed open-field tests on house mice (Mus domesticus) from four replicate lines genetically selected for high voluntary wheel-running for 22 generations and from four replicate random-bred control lines. Individual mice were recorded by video camera for 3 min in a 1-m2 open-field arena on 2 consecutive days. Mice from selected lines showed no statistical differences from control mice with respect to distance traveled, defecation, time spent in the interior, or average distance from the center of the arena during the trial. Thus, we found little evidence that open-field behavior, as traditionally defined, is genetically correlated with wheel-running behavior. This result is a useful converse test of classical studies that report no increased wheel-running in mice selected for increased open-field activity. However, mice from selected lines turned less in their travel paths than did control-line mice, and females from selected lines had slower travel times (longer latencies) to reach the wall. We discuss these results in the context of the historical open-field test and newly defined measures of open-field activity.

Altered Running Economy Directly Translates to Altered Distance-Running Performance.

PubMed

Hoogkamer, Wouter; Kipp, Shalaya; Spiering, Barry A; Kram, Rodger

2016-11-01

Our goal was to quantify if small (1%-3%) changes in running economy quantitatively affect distance-running performance. Based on the linear relationship between metabolic rate and running velocity and on earlier observations that added shoe mass increases metabolic rate by ~1% per 100 g per shoe, we hypothesized that adding 100 and 300 g per shoe would slow 3000-m time-trial performance by 1% and 3%, respectively. Eighteen male sub-20-min 5-km runners completed treadmill testing, and three 3000-m time trials wearing control shoes and identical shoes with 100 and 300 g of discreetly added mass. We measured rates of oxygen consumption and carbon dioxide production and calculated metabolic rates for the treadmill tests, and we recorded overall running time for the time trials. Adding mass to the shoes significantly increased metabolic rate at 3.5 m·s by 1.11% per 100 g per shoe (95% confidence interval = 0.88%-1.35%). While wearing the control shoes, participants ran the 3000-m time trial in 626.1 ± 55.6 s. Times averaged 0.65% ± 1.36% and 2.37% ± 2.09% slower for the +100-g and +300-g shoes, respectively (P < 0.001). On the basis of a linear fit of all the data, 3000-m time increased 0.78% per added 100 g per shoe (95% confidence interval = 0.52%-1.04%). Adding shoe mass predictably degrades running economy and slows 3000-m time-trial performance proportionally. Our data demonstrate that laboratory-based running economy measurements can accurately predict changes in distance-running race performance due to shoe modifications.

Walking, running and the evolution of short toes in humans.

PubMed

Rolian, Campbell; Lieberman, Daniel E; Hamill, Joseph; Scott, John W; Werbel, William

2009-03-01

The phalangeal portion of the forefoot is extremely short relative to body mass in humans. This derived pedal proportion is thought to have evolved in the context of committed bipedalism, but the benefits of shorter toes for walking and/or running have not been tested previously. Here, we propose a biomechanical model of toe function in bipedal locomotion that suggests that shorter pedal phalanges improve locomotor performance by decreasing digital flexor force production and mechanical work, which might ultimately reduce the metabolic cost of flexor force production during bipedal locomotion. We tested this model using kinematic, force and plantar pressure data collected from a human sample representing normal variation in toe length (N=25). The effect of toe length on peak digital flexor forces, impulses and work outputs was evaluated during barefoot walking and running using partial correlations and multiple regression analysis, controlling for the effects of body mass, whole-foot and phalangeal contact times and toe-out angle. Our results suggest that there is no significant increase in digital flexor output associated with longer toes in walking. In running, however, multiple regression analyses based on the sample suggest that increasing average relative toe length by as little as 20% doubles peak digital flexor impulses and mechanical work, probably also increasing the metabolic cost of generating these forces. The increased mechanical cost associated with long toes in running suggests that modern human forefoot proportions might have been selected for in the context of the evolution of endurance running.

Implementation of a Surgical Safety Checklist: Interventions to Optimize the Process and Hints to Increase Compliance

PubMed Central

Sendlhofer, Gerald; Mosbacher, Nina; Karina, Leitgeb; Kober, Brigitte; Jantscher, Lydia; Berghold, Andrea; Pregartner, Gudrun; Brunner, Gernot; Kamolz, Lars Peter

2015-01-01

Background A surgical safety checklist (SSC) was implemented and routinely evaluated within our hospital. The purpose of this study was to analyze compliance, knowledge of and satisfaction with the SSC to determine further improvements. Methods The implementation of the SSC was observed in a pilot unit. After roll-out into each operating theater, compliance with the SSC was routinely measured. To assess subjective and objective knowledge, as well as satisfaction with the SSC implementation, an online survey (N = 891) was performed. Results During two test runs in a piloting unit, 305 operations were observed, 175 in test run 1 and 130 in test run 2. The SSC was used in 77.1% of all operations in test run 1 and in 99.2% in test run 2. Within used SSCs, completion rates were 36.3% in test run 1 and 1.6% in test run 2. After roll-out, three unannounced audits took place and showed that the SSC was used in 95.3%, 91.9% and 89.9%. Within used SSCs, completion rates decreased from 81.7% to 60.6% and 53.2%. In 2014, 164 (18.4%) operating team members responded to the online survey, 160 of which were included in the analysis. 146 (91.3%) consultants and nursing staff reported to use the SSC regularly in daily routine. Conclusion These data show that the implementation of new tools such as the adapted WHO SSC needs constant supervision and instruction until it becomes self-evident and accepted. Further efforts, consisting mainly of hands-on leadership and training are necessary. PMID:25658317

High intensity interval training vs. high-volume running training during pre-season conditioning in high-level youth football: a cross-over trial.

PubMed

Faude, Oliver; Schnittker, Reinhard; Schulte-Zurhausen, Roman; Müller, Florian; Meyer, Tim

2013-01-01

We aimed at comparing the endurance effects of high-intensity interval training (HIIT) with high-volume running training (HVT) during pre-season conditioning in 20 high-level youth football players (15.9 (s 0.8) years). Players either conducted HVT or HIIT during the summer preparation period. During winter preparation they performed the other training programme. Before and after each training period several fitness tests were conducted: multi-stage running test (to assess the individual anaerobic threshold (IAT) and maximal running velocity (Vmax)), vertical jumping height, and straight sprinting. A significant increase from pre- to post-test was observed in IAT velocity (P < 0.001) with a greater increase after HVT (+0.8 km · h(-1) vs. +0.5 km · h(-1) after HIIT, P = 0.04). Maximal velocity during the incremental exercise test also slightly increased with time (P = 0.09). Forty per cent (HIIT) and 15% (HVT) of all players did not improve IAT beyond baseline variability. The players who did not respond to HIIT were significantly slower during 30 m sprinting than responders (P = 0.02). No further significant differences between responders and non-responders were observed. Jump heights deteriorated significantly after both training periods (P < 0.003). Both training programmes seem to be promising means to improve endurance capacity in high-level youth football players during pre-season conditioning.

AMPK and PPARδ agonists are exercise mimetics

PubMed Central

Narkar, Vihang A.; Downes, Michael; Yu, Ruth T.; Embler, Emi; Wang, Yong-Xu; Banayo, Ester; Mihaylova, Maria M.; Nelson, Michael C.; Zou, Yuhua; Juguilon, Henry; Kang, Heonjoong; Shaw, Reuben; Evans, Ronald M.

2008-01-01

SUMMARY The benefits of endurance exercise on general health make it desirable to identify orally active agents that would mimic or potentiate the effects of exercise to treat metabolic diseases. Although certain natural compounds, such as reseveratrol, have endurance-enhancing activities, their exact metabolic targets remain elusive. We therefore tested the effect of pathway-specific drugs on endurance capacities of mice in a treadmill running test. We found that PPARβ/δ agonist and exercise training synergistically increase oxidative myofibers and running endurance in adult mice. Because training activates AMPK and PGC1α, we then tested whether the orally active AMPK agonist AICAR might be sufficient to overcome the exercise requirement. Unexpectedly, even in sedentary mice, 4 weeks of AICAR treatment alone induced metabolic genes and enhanced running endurance by 44%. These results demonstrate that AMPK-PPARδ pathway can be targeted by orally active drugs to enhance training adaptation or even to increase endurance without exercise. PMID:18674809

Effect of 8 weeks of concurrent plyometric and running training on spatiotemporal and physiological variables of novice runners.

PubMed

Gómez-Molina, Josué; Ogueta-Alday, Ana; Camara, Jesus; Stickley, Christopher; García-López, Juan

2018-03-01

Concurrent plyometric and running training has the potential to improve running economy (RE) and performance through increasing muscle strength and power, but the possible effect on spatiotemporal parameters of running has not been studied yet. The aim of this study was to compare the effect of 8 weeks of concurrent plyometric and running training on spatiotemporal parameters and physiological variables of novice runners. Twenty-five male participants were randomly assigned into two training groups; running group (RG) (n = 11) and running + plyometric group (RPG) (n = 14). Both groups performed 8 weeks of running training programme, and only the RPG performed a concurrent plyometric training programme (two sessions per week). Anthropometric, physiological (VO 2max , heart rate and RE) and spatiotemporal variables (contact and flight times, step rate and length) were registered before and after the intervention. In comparison to RG, the RPG reduced step rate and increased flight times at the same running speeds (P < .05) while contact times remained constant. Significant increases in pre- and post-training (P < .05) were found in RPG for squat jump and 5 bound test, while RG remained unchanged. Peak speed, ventilatory threshold (VT) speed and respiratory compensation threshold (RCT) speed increased (P < .05) for both groups, although peak speed and VO 2max increased more in the RPG than in the RG. In conclusion, concurrent plyometric and running training entails a reduction in step rate, as well as increases in VT speed, RCT speed, peak speed and VO 2max . Athletes could benefit from plyometric training in order to improve their strength, which would contribute to them attaining higher running speeds.

Cloning and establishment of a line of rats for high levels of voluntary wheel running.

PubMed

Morishima-Yamato, Masaki; Hisaoka, Fumiko; Shinomiya, Sachiko; Harada, Nagakatsu; Matoba, Hideki; Takahashi, Akira; Nakaya, Yutaka

2005-06-17

We generated an original Wistar line of rats that displayed increased levels of wheel running, which we named SPORTS (Spontaneously-Running-Tokushima-Shikoku). Male SPORTS rats ran voluntarily in a running wheel almost six times longer than male control Wistar rats, established without selection for their running activity. The running phenotype of female SPORTS rats was the same as female control Wistar rats. However, male offspring from the cross-mating between a female SPORTS rat and a male control rat also showed a similar level of hyper-running activity as the original SPORTS line. Compared to control rats, male SPORTS rats had lower levels of mean body weight, abdominal fat and plasma insulin after 4 weeks of running. It is likely that all these beneficial changes observed in the SPORTS rats reflected the increases in glucose disposal we observed in oral glucose tolerance tests carried out on the animals. We also found hyper-running caused a significant increase in skeletal muscle oxidative capacity, measured as the ratio of malate dehydrogenase to phosphofructokinase activity, an index of aerobic metabolism. These results indicate that the SPORTS rat may be a good animal model for determining the mechanisms responsible for up-regulation of running motivation, in addition to investigating changes in nutrient metabolism induced by high intensity exercise.

Running With an Elastic Lower Limb Exoskeleton.

PubMed

Cherry, Michael S; Kota, Sridhar; Young, Aaron; Ferris, Daniel P

2016-06-01

Although there have been many lower limb robotic exoskeletons that have been tested for human walking, few devices have been tested for assisting running. It is possible that a pseudo-passive elastic exoskeleton could benefit human running without the addition of electrical motors due to the spring-like behavior of the human leg. We developed an elastic lower limb exoskeleton that added stiffness in parallel with the entire lower limb. Six healthy, young subjects ran on a treadmill at 2.3 m/s with and without the exoskeleton. Although the exoskeleton was designed to provide ~50% of normal leg stiffness during running, it only provided 24% of leg stiffness during testing. The difference in added leg stiffness was primarily due to soft tissue compression and harness compliance decreasing exoskeleton displacement during stance. As a result, the exoskeleton only supported about 7% of the peak vertical ground reaction force. There was a significant increase in metabolic cost when running with the exoskeleton compared with running without the exoskeleton (ANOVA, P < .01). We conclude that 2 major roadblocks to designing successful lower limb robotic exoskeletons for human running are human-machine interface compliance and the extra lower limb inertia from the exoskeleton.

Influence of footwear designed to boost energy return on running economy in comparison to a conventional running shoe.

PubMed

Sinclair, J; Mcgrath, R; Brook, O; Taylor, P J; Dillon, S

2016-01-01

Running economy is a reflection of the amount of inspired oxygen required to maintain a given velocity and is considered a determining factor for running performance. Athletic footwear has been advocated as a mechanism by which running economy can be enhanced. New commercially available footwear has been developed in order to increase energy return, although their efficacy has not been investigated. This study aimed to examine the effects of energy return footwear on running economy in relation to conventional running shoes. Twelve male runners completed 6-min steady-state runs in conventional and energy return footwear. Overall, oxygen consumption (VO2), heart rate, respiratory exchange ratio, shoe comfort and rating of perceived exertion were assessed. Moreover, participants subjectively indicated which shoe condition they preferred for running. Differences in shoe comfort and physiological parameters were examined using Wilcoxon signed-rank tests, whilst shoe preferences were tested using a chi-square analysis. The results showed that VO2 and respiratory exchange ratio were significantly lower, and shoe comfort was significantly greater, in the energy return footwear. Given the relationship between running economy and running performance, these observations indicate that the energy return footwear may be associated with enhanced running performance in comparison to conventional shoes.

Side-suspended High-Tc Superconducting Maglev Prototype Vehicle Running at a High Speed in an Evacuated Circular Test Track

NASA Astrophysics Data System (ADS)

Zhou, Dajin; Zhao, Lifeng; Cui, Chenyu; Zhang, Yong; Guo, Jianqiang; Zhao, Yong

2017-07-01

High-T c superconductor (HTS) and permanent magnetic guideway (PMG) based maglev train is intensively studied in China, Japan, Germany and Brazil, mainly through static or vibration test. Amongst these studies, only a few of reports are available for the direct and effective assessment on the dynamic performance of the HTS maglev vehicle by running on a straight or circular PMG track. The highest running speed of these experiments is lower than 50 km/h. In this paper, a side-suspended HTS permanent magnetic guideway maglev system was proposed and constructed in order to increase the running speed in a circular track. By optimizing the arrangement of YBCO bulks besides the PMG, the side-suspended HTS maglev prototype vehicle was successfully running stably at a speed as high as 150 km/h in a circular test track with 6.5 m in diameter, and in an evacuated tube environment, in which the pressure is 5 × 103 Pa.

The relationship between gamma frequency and running speed differs for slow and fast gamma rhythms in freely behaving rats

PubMed Central

Zheng, Chenguang; Bieri, Kevin Wood; Trettel, Sean Gregory; Colgin, Laura Lee

2015-01-01

In hippocampal area CA1 of rats, the frequency of gamma activity has been shown to increase with running speed (Ahmed and Mehta, 2012). This finding suggests that different gamma frequencies simply allow for different timings of transitions across cell assemblies at varying running speeds, rather than serving unique functions. However, accumulating evidence supports the conclusion that slow (~25–55 Hz) and fast (~60–100 Hz) gamma are distinct network states with different functions. If slow and fast gamma constitute distinct network states, then it is possible that slow and fast gamma frequencies are differentially affected by running speed. In this study, we tested this hypothesis and found that slow and fast gamma frequencies change differently as a function of running speed in hippocampal areas CA1 and CA3, and in the superficial layers of the medial entorhinal cortex (MEC). Fast gamma frequencies increased with increasing running speed in all three areas. Slow gamma frequencies changed significantly less across different speeds. Furthermore, at high running speeds, CA3 firing rates were low, and MEC firing rates were high, suggesting that CA1 transitions from CA3 inputs to MEC inputs as running speed increases. These results support the hypothesis that slow and fast gamma reflect functionally distinct states in the hippocampal network, with fast gamma driven by MEC at high running speeds and slow gamma driven by CA3 at low running speeds. PMID:25601003

Burrowing as a novel voluntary strength training method for mice: A comparison of various voluntary strength or resistance exercise methods.

PubMed

Roemers, P; Mazzola, P N; De Deyn, P P; Bossers, W J; van Heuvelen, M J G; van der Zee, E A

2018-04-15

Voluntary strength training methods for rodents are necessary to investigate the effects of strength training on cognition and the brain. However, few voluntary methods are available. The current study tested functional and muscular effects of two novel voluntary strength training methods, burrowing (digging a substrate out of a tube) and unloaded tower climbing, in male C57Bl6 mice. To compare these two novel methods with existing exercise methods, resistance running and (non-resistance) running were included. Motor coordination, grip strength and muscle fatigue were measured at baseline, halfway through and near the end of a fourteen week exercise intervention. Endurance was measured by an incremental treadmill test after twelve weeks. Both burrowing and resistance running improved forelimb grip strength as compared to controls. Running and resistance running increased endurance in the treadmill test and improved motor skills as measured by the balance beam test. Post-mortem tissue analyses revealed that running and resistance running induced Soleus muscle hypertrophy and reduced epididymal fat mass. Tower climbing elicited no functional or muscular changes. As a voluntary strength exercise method, burrowing avoids the confounding effects of stress and positive reinforcers elicited in forced strength exercise methods. Compared to voluntary resistance running, burrowing likely reduces the contribution of aerobic exercise components. Burrowing qualifies as a suitable voluntary strength training method in mice. Furthermore, resistance running shares features of strength training and endurance (aerobic) exercise and should be considered a multi-modal aerobic-strength exercise method in mice. Copyright © 2017 Elsevier B.V. All rights reserved.

Effects of Cycling Versus Running Training on Sprint and Endurance Capacity in Inline Speed Skating

PubMed Central

Stangier, Carolin; Abel, Thomas; Mierau, Julia; Hollmann, Wildor; Strüder, Heiko K.

2016-01-01

The purpose of this study was to compare the effects of running versus cycling training on sprint and endurance capacity in inline speed skating. Sixteen elite athletes (8 male, 8 female, 24 ± 8 yrs) were randomly assigned into 2 training groups performing either 2 session per week of treadmill running or ergometer cycling in addition to 3 skating specific sessions (technique, plyometrics, parkour) for 8 weeks. Training intensity was determined within non-specific (cycling or running) and effects on specific endurance capacity within a specific incremental exercise test. Before and after the intervention all athletes performed a specific (300m) and one non-specific (30s cycling or 200m running) all-out sprint test according to the group affiliation. To determine the accumulation of blood lactate (BLa) and glucose (BGL) 20 μl arterialized blood was drawn at rest, as well as in 1 min intervals for 10 min after the sprint test. The sport-specific peak oxygen uptake (VO2 peak) was significantly increased (+17%; p = 0.01) in both groups and highly correlated with the sprint performance (r = -0.71). BLa values decreased significantly (-18%, p = 0.02) after the specific sprint test from pre to post-testing without any group effect. However, BGL values only showed a significant decrease (-2%, p = 0.04) in the running group. The close relationship between aerobic capacity and sprint performance in inline speed skating highlights the positive effects of endurance training. Although both training programs were equally effective in improving endurance and sprint capacities, the metabolic results indicate a faster recovery after high intensity efforts for all athletes, as well as a higher reliance on the fat metabolism for athletes who trained in the running group. Key points In addition to a highly developed aerobic performance inline speed skaters also require a highly trained anaerobic capacity to be effective in the sprint sections such as the mass start, tactical attacks and finish line sprint. An 8-week low-intensity endurance training program of either cycling or running training combined with additional routine training improves classical aerobic characteristics (17% increase of VO2 peak), as well as values for acceleration and speed. Athletes who trained in the running group demonstrated a higher reliance on the fat metabolism in the sport-specific post-testing. The significant reduction in anaerobic ATP turnover during repeated sprints appears to be partially compensated by an increase in VO2 in subsequent sprint. The results revealed a close relationship between the aerobic capacity and sprint performance in inline speed skating. PMID:26957925

Effects of Short or Long Warm-up on Intermediate Running Performance.

PubMed

van den Tillaar, Roland; Vatten, Tormod; von Heimburg, Erna

2017-01-01

van den Tillaar, R, Vatten, T, and von Heimburg, E. Effects of short or long warm-up on intermediate running performance. J Strength Cond Res 31(1): 37-44, 2017-The aim of the study was to compare the effects of a long warm-up (general + specific) and a short warm-up (specific) on intermediate running performance (3-minute run). Thirteen experienced endurance-trained athletes (age 23.2 ± 2.3 years, body mass 79.8 ± 8.2 kg, body height 1.82 ± 0.05 m) conducted 2 types of warm-ups in a crossover design with 1 week in between: a long warm-up (10 minutes, 80% maximal heart rate, and 8 × 60 m sprint with increasing intensity and 1 minute rest in between) and a short warm-up (8 × 60 m sprint with increasing intensity and 1 minute rest in between). Each warm-up was followed by a 3-minute running test on a nonmotorized treadmill. Total running distance, running velocity at each 30 seconds, heart rate, blood lactate concentration, oxygen uptake, and rate of perceived exertion were measured. No significant differences in running performance variables and physiological parameters were found between the 2 warm-up protocols, except for the rate of perceived exertion and heart rate, which were higher after the long warm-up and after the 3-minute running test compared with the short warm-up. It was concluded that a short warm-up is as effective as a long warm-up for intermediate performance. Therefore, athletes can choose for themselves if they want to include a general part in their warm-up routines, even though it would not enhance their running performance more compared with only using a short, specific warm-up. However, to increase efficiency of time for training or competition, these short, specific warm-ups should be performed instead of long warm-ups.

Cognitive and locomotor/exploratory behavior after chronic exercise in the olfactory bulbectomy animal model of depression.

PubMed

Van Hoomissen, Jacqueline; Kunrath, Julie; Dentlinger, Renee; Lafrenz, Andrew; Krause, Mark; Azar, Afaf

2011-09-12

Despite the evidence that exercise improves cognitive behavior in animal models, little is known about these beneficial effects in animal models of pathology. We examined the effects of activity wheel (AW) running on contextual fear conditioning (CFC) and locomotor/exploratory behavior in the olfactory bulbectomy (OBX) model of depression, which is characterized by hyperactivity and changes in cognitive function. Twenty-four hours after the conditioning session of the CFC protocol, the animals were tested for the conditioned response in a conditioned and a novel context to test for the effects of both AW and OBX on CFC, but also the context specificity of the effect. OBX reduced overall AW running behavior throughout the experiment, but increased locomotor/exploratory behavior during CFC, thus demonstrating a context-dependent effect. OBX animals, however, displayed normal CFC behavior that was context-specific, indicating that aversively conditioned memory is preserved in this model. AW running increased freezing behavior during the testing session of the CFC protocol in the control animals but only in the conditioned context, supporting the hypothesis that AW running improves cognitive function in a context-specific manner that does not generalize to an animal model of pathology. Blood corticosterone levels were increased in all animals at the conclusion of the testing sessions, but levels were higher in AW compared to sedentary groups indicating an effect of exercise on neuroendocrine function. Given the differential results of AW running on behavior and neuroendocrine function after OBX, further exploration of the beneficial effects of exercise in animal models of neuropathology is warranted. Copyright © 2011 Elsevier B.V. All rights reserved.

Methodological framework for heart rate variability analysis during exercise: application to running and cycling stress testing.

PubMed

Hernando, David; Hernando, Alberto; Casajús, Jose A; Laguna, Pablo; Garatachea, Nuria; Bailón, Raquel

2018-05-01

Standard methodologies of heart rate variability analysis and physiological interpretation as a marker of autonomic nervous system condition have been largely published at rest, but not so much during exercise. A methodological framework for heart rate variability (HRV) analysis during exercise is proposed, which deals with the non-stationary nature of HRV during exercise, includes respiratory information, and identifies and corrects spectral components related to cardiolocomotor coupling (CC). This is applied to 23 male subjects who underwent different tests: maximal and submaximal, running and cycling; where the ECG, respiratory frequency and oxygen consumption were simultaneously recorded. High-frequency (HF) power results largely modified from estimations with the standard fixed band to those obtained with the proposed methodology. For medium and high levels of exercise and recovery, HF power results in a 20 to 40% increase. When cycling, HF power increases around 40% with respect to running, while CC power is around 20% stronger in running.

Increased adult hippocampal neurogenesis is not necessary for wheel running to abolish conditioned place preference for cocaine in mice.

PubMed

Mustroph, M L; Merritt, J R; Holloway, A L; Pinardo, H; Miller, D S; Kilby, C N; Bucko, P; Wyer, A; Rhodes, J S

2015-01-01

Recent evidence suggests that wheel running can abolish conditioned place preference (CPP) for cocaine in mice. Running significantly increases the number of new neurons in the hippocampus, and new neurons have been hypothesised to enhance plasticity and behavioral flexibility. Therefore, we tested the hypothesis that increased neurogenesis was necessary for exercise to abolish cocaine CPP. Male nestin-thymidine kinase transgenic mice were conditioned with cocaine, and then housed with or without running wheels for 32 days. Half of the mice were fed chow containing valganciclovir to induce apoptosis in newly divided neurons, and the other half were fed standard chow. For the first 10 days, mice received daily injections of bromodeoxyuridine (BrdU) to label dividing cells. On the last 4 days, mice were tested for CPP, and then euthanized for measurement of adult hippocampal neurogenesis by counting the number of BrdU-positive neurons in the dentate gyrus. Levels of running were similar in mice fed valganciclovir-containing chow and normal chow. Valganciclovir significantly reduced the numbers of neurons (BrdU-positive/NeuN-positive) in the dentate gyrus of both sedentary mice and runner mice. Valganciclovir-fed runner mice showed similar levels of neurogenesis as sedentary, normal-fed controls. However, valganciclovir-fed runner mice showed the same abolishment of CPP as runner mice with intact neurogenesis. The results demonstrate that elevated adult hippocampal neurogenesis resulting from running is not necessary for running to abolish cocaine CPP in mice. © 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Effects of endurance training and competition on exercise tests in relatively untrained people.

PubMed

Verstappen, F T; Janssen, G M; Does, R J

1989-10-01

One hundred fourteen subjects (34 +/- 8 years) without any competition background took part in an endurance training study to be completed after 1.5 years with running a marathon. Ultimately, 60 males and 18 females achieved that goal. The training program, carefully supervised, was divided into three phases with a maximum of 45, 70, and 110 km/week training volume and concluded with a performance race of 15, 25, and 42.195 km, respectively. Three days before and 3 and 5 days after each race, 35 subjects were selected to perform a progressive treadmill test and the remaining subjects participated in performing field tests of running 400 and 1000 m. The maximal velocity achieved in the treadmill test was 4.75 +/- 0.36 m.s-1 for males and 4.18 +/- 0.28 m.s-1 for females; it remained constant throughout the study. However, the running velocity at 4 mmol.1(-1) plasma lactate concentration increased about 10% from phase 1 to 3. In the females this rise already appeared to be completed in phase 2. Heart rate showed a tendency to increase at both submaximal and maximal exercise from training phase 1 to 2 and 3, whereas plasma lactate concentration showed a decreasing tendency. Three days after the 25 km and the marathon race the maximal running velocity in the exercise test was 2%-4% lower compared with the pre-race test (P less than 0.05). Five days after the race this difference again faded away. This small decline in running performance was not reflected in changes of physiologic responses such as heart rate or plasma lactate concentration.

Whole blood coagulation and platelet activation in the athlete: a comparison of marathon, triathlon and long distance cycling.

PubMed

Hanke, Alexander A; Staib, A; Görlinger, K; Perrey, M; Dirkmann, D; Kienbaum, P

2010-02-26

Serious thrombembolic events occur in otherwise healthy marathon athletes during competition. We tested the hypothesis that during heavy endurance sports coagulation and platelets are activated depending on the type of endurance sport with respect to its running fraction. 68 healthy athletes participating in marathon (MAR, running 42 km, n = 24), triathlon (TRI, swimming 2.5 km + cycling 90 km + running 21 km, n = 22), and long distance cycling (CYC, 151 km, n = 22) were included in the study. Blood samples were taken before and immediately after completion of competition to perform rotational thrombelastometry. We assessed coagulation time (CT), maximum clot firmness (MCF) after intrinsically activation and fibrin polymerization (FIBTEM). Furthermore, platelet aggregation was tested after activation with ADP and thrombin activating peptide 6 (TRAP) by using multiple platelet function analyzer. Complete data sets were obtained in 58 athletes (MAR: n = 20, TRI: n = 19, CYC: n = 19). CT significantly decreased in all groups (MAR -9.9%, TRI -8.3%, CYC -7.4%) without differences between groups. In parallel, MCF (MAR +7.4%, TRI +6.1%, CYC +8.3%) and fibrin polymerization (MAR +14.7%, TRI +6.1%, CYC +8.3%) were significantly increased in all groups. However, platelets were only activated during MAR and TRI as indicated by increased AUC during TRAP-activation (MAR +15.8%) and increased AUC during ADP-activation in MAR (+50.3%) and TRI (+57.5%). While coagulation is activated during physical activity irrespective of type we observed significant platelet activation only during marathon and to a lesser extent during triathlon. We speculate that prolonged running may increase platelet activity, possibly, due to mechanical alteration. Thus, particularly prolonged running may increase the risk of thrombembolic incidents in running athletes.

Whole blood coagulation and platelet activation in the athlete: A comparison of marathon, triathlon and long distance cycling

PubMed Central

2010-01-01

Introduction Serious thrombembolic events occur in otherwise healthy marathon athletes during competition. We tested the hypothesis that during heavy endurance sports coagulation and platelets are activated depending on the type of endurance sport with respect to its running fraction. Materials and Methods 68 healthy athletes participating in marathon (MAR, running 42 km, n = 24), triathlon (TRI, swimming 2.5 km + cycling 90 km + running 21 km, n = 22), and long distance cycling (CYC, 151 km, n = 22) were included in the study. Blood samples were taken before and immediately after completion of competition to perform rotational thrombelastometry. We assessed coagulation time (CT), maximum clot firmness (MCF) after intrinsically activation and fibrin polymerization (FIBTEM). Furthermore, platelet aggregation was tested after activation with ADP and thrombin activating peptide 6 (TRAP) by using multiple platelet function analyzer. Results Complete data sets were obtained in 58 athletes (MAR: n = 20, TRI: n = 19, CYC: n = 19). CT significantly decreased in all groups (MAR -9.9%, TRI -8.3%, CYC -7.4%) without differences between groups. In parallel, MCF (MAR +7.4%, TRI +6.1%, CYC +8.3%) and fibrin polymerization (MAR +14.7%, TRI +6.1%, CYC +8.3%) were significantly increased in all groups. However, platelets were only activated during MAR and TRI as indicated by increased AUC during TRAP-activation (MAR +15.8%) and increased AUC during ADP-activation in MAR (+50.3%) and TRI (+57.5%). Discussion While coagulation is activated during physical activity irrespective of type we observed significant platelet activation only during marathon and to a lesser extent during triathlon. We speculate that prolonged running may increase platelet activity, possibly, due to mechanical alteration. Thus, particularly prolonged running may increase the risk of thrombembolic incidents in running athletes. PMID:20452885

Heavy strength training improves running and cycling performance following prolonged submaximal work in well-trained female athletes.

PubMed

Vikmoen, Olav; Rønnestad, Bent R; Ellefsen, Stian; Raastad, Truls

2017-03-01

The purpose of this study was to investigate the effects of adding heavy strength training to female duathletes' normal endurance training on both cycling and running performance. Nineteen well-trained female duathletes ( V O 2max cycling: 54 ± 3 ml∙kg -1 ∙min -1 , VO 2max running: 53 ± 3 ml∙kg -1 ∙min -1 ) were randomly assigned to either normal endurance training ( E , n  = 8) or normal endurance training combined with strength training ( E+S , n  = 11). The strength training consisted of four lower body exercises [3 × 4-10 repetition maximum (RM)] twice a week for 11 weeks. Running and cycling performance were assessed using 5-min all-out tests, performed immediately after prolonged periods of submaximal work (3 h cycling or 1.5 h running). E+S increased 1RM in half squat (45 ± 22%) and lean mass in the legs (3.1 ± 4.0%) more than E Performance during the 5-min all-out test increased in both cycling (7.0 ± 4.5%) and running (4.7 ± 6.0%) in E+S, whereas no changes occurred in E The changes in running performance were different between groups. E+S reduced oxygen consumption and heart rate during the final 2 h of prolonged cycling, whereas no changes occurred in E No changes occurred during the prolonged running in any group. Adding strength training to normal endurance training in well-trained female duathletes improved both running and cycling performance when tested immediately after prolonged submaximal work. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

Economic growth, combustible renewables and waste consumption, and CO₂ emissions in North Africa.

PubMed

Ben Jebli, Mehdi; Ben Youssef, Slim

2015-10-01

This paper uses panel cointegration techniques and Granger causality tests to examine the dynamic causal link between per capita real gross domestic product (GDP), combustible renewables and waste (CRW) consumption, and CO2 emissions for a panel of five North African countries during the period 1971-2008. Granger causality test results suggest short- and long-run unidirectional causalities running from CO2 emissions and CRW consumption to real GDP and a short-run unidirectional causality running from CRW to CO2 emissions. The results from panel long-run fully modified ordinary least squares (FMOLS) and dynamic ordinary least squares (DOLS) estimates show that CO2 emissions and CRW consumption have a positive and statistically significant impact on GDP. Our policy recommendations are that these countries should use more CRW because this increases their output, reduces their energy dependency on fossil energy, and may decrease their CO2 emissions.

Development and testing of a new system for assessing wheel-running behaviour in rodents.

PubMed

Chomiak, Taylor; Block, Edward W; Brown, Andrew R; Teskey, G Campbell; Hu, Bin

2016-05-05

Wheel running is one of the most widely studied behaviours in laboratory rodents. As a result, improved approaches for the objective monitoring and gathering of more detailed information is increasingly becoming important for evaluating rodent wheel-running behaviour. Here our aim was to develop a new quantitative wheel-running system that can be used for most typical wheel-running experimental protocols. Here we devise a system that can provide a continuous waveform amenable to real-time integration with a high-speed video ideal for wheel-running experimental protocols. While quantification of wheel running behaviour has typically focused on the number of revolutions per unit time as an end point measure, the approach described here allows for more detailed information like wheel rotation fluidity, directionality, instantaneous velocity, and acceleration, in addition to total number of rotations, and the temporal pattern of wheel-running behaviour to be derived from a single trace. We further tested this system with a running-wheel behavioural paradigm that can be used for investigating the neuronal mechanisms of procedural learning and postural stability, and discuss other potentially useful applications. This system and its ability to evaluate multiple wheel-running parameters may become a useful tool for screening new potentially important therapeutic compounds related to many neurological conditions.

Reinforcement of drinking by running: effect of fixed ratio and reinforcement time1

PubMed Central

Premack, David; Schaeffer, Robert W.; Hundt, Alan

1964-01-01

Rats were required to complete varying numbers of licks (FR), ranging from 10 to 300, in order to free an activity wheel for predetermined times (CT) ranging from 2 to 20 sec. The reinforcement of drinking by running was shown both by an increased frequency of licking, and by changes in length of the burst of licking relative to operant-level burst length. In log-log coordinates, instrumental licking tended to be a linear increasing function of FR for the range tested, a linear decreasing function of CT for the range tested. Pause time was implicated in both of the above relations, being a generally increasing function of both FR and CT. PMID:14120150

REINFORCEMENT OF DRINKING BY RUNNING: EFFECT OF FIXED RATIO AND REINFORCEMENT TIME.

PubMed

PREMACK, D; SCHAEFFER, R W; HUNDT, A

1964-01-01

Rats were required to complete varying numbers of licks (FR), ranging from 10 to 300, in order to free an activity wheel for predetermined times (CT) ranging from 2 to 20 sec. The reinforcement of drinking by running was shown both by an increased frequency of licking, and by changes in length of the burst of licking relative to operant-level burst length. In log-log coordinates, instrumental licking tended to be a linear increasing function of FR for the range tested, a linear decreasing function of CT for the range tested. Pause time was implicated in both of the above relations, being a generally increasing function of both FR and CT.

Exhaustive Exercise-induced Oxidative Stress Alteration of Erythrocyte Oxygen Release Capacity.

PubMed

Xiong, Yanlian; Xiong, Yanlei; Wang, Yueming; Zhao, Yajin; Li, Yaojin; Ren, Yang; Wang, Ruofeng; Zhao, Mingzi; Hao, Yitong; Liu, Haibei; Wang, Xiang

2018-05-24

The aim of the present study is to explore the effect of exhaustive running exercise (ERE) in the oxygen release capacity of rat erythrocytes. Rats were divided into sedentary control (C), moderate running exercise (MRE) and exhaustive running exercise groups. The thermodynamics and kinetics properties of the erythrocyte oxygen release process of different groups were tested. We also determined the degree of band-3 oxidative and phosphorylation, anion transport activity and carbonic anhydrase isoform II(CAII) activity. Biochemical studies suggested that exhaustive running significantly increased oxidative injury parameters in TBARS and methaemoglobin levels. Furthermore, exhaustive running significantly decreased anion transport activity and carbonic anhydrase isoform II(CAII) activity. Thermodynamic analysis indicated that erythrocytes oxygen release ability also significantly increased due to elevated 2,3-DPG level after exhaustive running. Kinetic analysis indicated that exhaustive running resulted in significantly decreased T50 value. We presented evidence that exhaustive running remarkably impacted thermodynamics and kinetics properties of RBCs oxygen release. In addition, changes in 2,3-DPG levels and band-3 oxidation and phosphorylation could be the driving force for exhaustive running induced alterations in erythrocytes oxygen release thermodynamics and kinetics properties.

Voluntary wheel running in dystrophin-deficient (mdx) mice: Relationships between exercise parameters and exacerbation of the dystrophic phenotype.

PubMed

Smythe, Gayle M; White, Jason D

2011-12-18

Voluntary wheel running can potentially be used to exacerbate the disease phenotype in dystrophin-deficient mdx mice. While it has been established that voluntary wheel running is highly variable between individuals, the key parameters of wheel running that impact the most on muscle pathology have not been examined in detail. We conducted a 2-week test of voluntary wheel running by mdx mice and the impact of wheel running on disease pathology. There was significant individual variation in the average daily distance (ranging from 0.003 ± 0.005 km to 4.48 ± 0.96 km), culminating in a wide range (0.040 km to 67.24 km) of total cumulative distances run by individuals. There was also variation in the number and length of run/rest cycles per night, and the average running rate. Correlation analyses demonstrated that in the quadriceps muscle, a low number of high distance run/rest cycles was the most consistent indicator for increased tissue damage. The amount of rest time between running bouts was a key factor associated with gastrocnemius damage. These data emphasize the need for detailed analysis of individual running performance, consideration of the length of wheel exposure time, and the selection of appropriate muscle groups for analysis, when applying the use of voluntary wheel running to disease exacerbation and/or pre-clinical testing of the efficacy of therapeutic agents in the mdx mouse.

Mouse genetic differences in voluntary wheel running, adult hippocampal neurogenesis and learning on the multi-strain-adapted plus water maze

PubMed Central

Merritt, Jennifer; Rhodes, Justin S.

2014-01-01

Moderate levels of aerobic exercise broadly enhance cognition throughout the lifespan. One hypothesized contributing mechanism is increased adult hippocampal neurogenesis. Recently, we measured the effects of voluntary wheel running on adult hippocampal neurogenesis in 12 different mouse strains, and found increased neurogenesis in all strains, ranging from 2 to 5 fold depending on the strain. The purpose of this study was to determine the extent to which increased neurogenesis from wheel running is associated with enhanced performance on the water maze for 5 of the 12 strains, chosen based on their levels of neurogenesis observed in the previous study (C57BL/6J, 129S1/SvImJ, B6129SF1/J, DBA/2J, and B6D2F1/J). Mice were housed with or without a running wheels for 30 days then tested for learning and memory on the plus water maze, adapted for multiple strains, and rotarod test of motor performance. The first 10 days, animals were injected with BrdU to label dividing cells. After behavioral testing animals were euthanized to measure adult hippocampal neurogenesis using standard methods. Levels of neurogenesis depended on strain but all mice had a similar increase in neurogenesis in response to exercise. All mice acquired the water maze but performance depended on strain. Exercise improved water maze performance in all strains to a similar degree. Rotarod performance depended on strain. Exercise improved rotarod performance only in DBA/2J and B6D2F1/J mice. Taken together, results demonstrate that despite different levels of neurogenesis, memory performance and motor coordination in these mouse strains, all strains have the capacity to increase neurogenesis and improve learning on the water maze through voluntary wheel running. PMID:25435316

Is health care a luxury or a necessity or both? Evidence from Turkey.

PubMed

Yavuz, Nilgun Cil; Yilanci, Veli; Ozturk, Zehra Ayca

2013-02-01

This study investigates the effect of per capita income on per capita health expenditures in Turkey over the period 1975-2007 by using ARDL bounds test approach to the cointegration considering both demand and supply side variables. Since we reject the null hypothesis that there is no cointegration among the series, we estimate long run and short run elasticities. The results show that while income has no effect on health expenditures in the long run, it is a necessity good in the short run that is a 1% increase in per capita income creates an 0.75% increase in per capita health expenditures. On the other hand, by examining the coefficient of demand and supply side variables, we found that average length of stay and number of physicians has negative effect, percentage of older people has positive effect and infant mortality rate has no effect on health expenditures in both short and long runs.

Physical characteristics that predict involvement with the ball in recreational youth soccer.

PubMed

Ré, Alessandro H Nicolai; Cattuzzo, Maria Teresa; Henrique, Rafael Dos Santos; Stodden, David F

2016-09-01

This study examined the relative contribution of age, stage of puberty, anthropometric characteristics, health-related fitness, soccer-specific tests and match-related technical performance to variance in involvements with the ball during recreational 5-a-side small-sided (32 × 15 m) soccer matches. Using a cross-sectional design, 80 healthy male students (14.6 ± 0.5 years of age; range 13.6-15.4) who played soccer recreationally were randomly divided into 10 teams and played against each other. Measurements included height, body mass, pubertal status, health-related fitness (12-min walk/run test, standing long jump, 15-m sprint and sit-ups in 30 s), soccer-specific tests (kicking for speed, passing for accuracy and agility run with and without a ball), match-related technical performance (kicks, passes and dribbles) and involvements with the ball during matches. Forward multiple regression analysis revealed that cardiorespiratory fitness (12-min walk/run test) accounted for 36% of the variance in involvements with the ball. When agility with the ball (zigzag running) and power (standing long jump) were included among the predictors, the total explained variance increased to 62%. In conclusion, recreational adolescent players, regardless of their soccer-specific skills, may increase participation in soccer matches most through physical activities that promote improvement in cardiorespiratory fitness, muscle power and agility.

The antidepressant effect of running is associated with increased hippocampal cell proliferation.

PubMed

Bjørnebekk, Astrid; Mathé, Aleksander A; Brené, Stefan

2005-09-01

A common trait of antidepressant drugs, electroconvulsive treatment and physical exercise is that they relieve depression and up-regulate neurotrophic factors as well as cell proliferation and neurogenesis in the hippocampus. In order to identify possible biological underpinnings of depression and the antidepressant effect of running, we analysed cell proliferation, the level of the neurotrophic factor BDNF in hippocampus and dynorphin in striatum/accumbens in 'depressed' Flinders Sensitive Line rats (FSL) and Flinders Resistant Line (FRL) rats with and without access to running-wheels. The FRL strain exhibited a higher daily running activity than the FSL strain. Wheel-running had an antidepressant effect in the 'depressed' FSL rats, as indicated by the forced swim test. In the hippocampus, cell proliferation was lower in the 'depressed' rats compared to the control FRL rats but there was no difference in BDNF or dynorphin levels in striatum/accumbens. After 5 wk of running, cell proliferation increased in FSL but not in FRL rats. BDNF and dynorphin mRNA levels were increased in FRL but not to the same extent in the in FSL rats; thus, increased BDNF and dynorphin levels were correlated to the running activity but not to the antidepressant effect of running. The only parameter that was associated to basal level of 'depression' and to the antidepressant effect was cell proliferation in the hippocampus. Thus, suppression of cell proliferation in the hippocampus could constitute one of the mechanisms that underlie depression, and physical activity might be an efficient antidepressant.

Duration- and environment-dependent effects of repeated voluntary exercise on anxiety and cued fear in mice.

PubMed

Dubreucq, Sarah; Marsicano, Giovanni; Chaouloff, Francis

2015-04-01

Several studies have indicated that animal models of exercise, such as voluntary wheel running, might be endowed with anxiolytic properties. Using the light/dark test of unconditioned anxiety, we have reported that one confounding factor in the estimation of wheel running impacts on anxiety might be the housing condition of the sedentary controls. The present mouse study analyzed whether the aforementioned observation in the light/dark test (i) could be repeated in the elevated plus-maze and social interaction tests of unconditioned anxiety, (ii) extended to conditioned anxiety, as assessed during cued fear recall tests, and (iii) required unlimited daily access to the running wheel. Housing with a locked wheel or with a free wheel that allowed limited or unlimited running activity triggered anxiolysis in the light/dark test, but not in the elevated plus-maze test, compared to standard housing. In the social interaction test, the duration, but not the number, of social contacts was increased in mice provided unlimited (but not limited) access to a wheel, compared to standard housing or housing with a locked wheel. Lastly, freezing responses to a cue during fear recall tests indicated that the reduction in freezing observed in mice provided limited or unlimited access to the wheels was fully accounted for by housing with a wheel. Besides confirming that the housing condition of the sedentary controls might bias the estimation of the effects of wheel running on anxiety, this study further shows that this estimation is dependent on the test used to assess anxiety. Copyright © 2014 Elsevier B.V. All rights reserved.

Measurement of cardiorespiratory fitness in children from two commonly used field tests after accounting for body fatness and maturity.

PubMed

Hamlin, Michael J; Fraser, Meegan; Lizamore, Catherine A; Draper, Nick; Shearman, Jeremy P; Kimber, Nicholas E

2014-03-27

Body fat and maturation both influence cardiorespiratory fitness, however few studies have taken these variables into account when using field tests to predict children's fitness levels. The purpose of this study was to determine the relationship between two field tests of cardiorespiratory fitness (20 m Maximal Multistage Shuttle Run [20-MST], 550 m distance run [550-m]) and direct measurement of VO2max after adjustment for body fatness and maturity levels. Fifty-three participants (25 boys, 28 girls, age 10.6 ± 1.2 y, mean ± SD) had their body fat levels estimated using bioelectrical impedance (16.6% ± 6.0% and 20.0% ± 5.8% for boys and girls, respectively). Participants performed in random order, the 20-MST and 550-m run followed by a progressive treadmill test to exhaustion during which gas exchange measures were taken. Pearson correlation coefficient analysis revealed that the participants' performance in the 20-MST and 550-m run were highly correlated to VO2max obtained during the treadmill test to exhaustion (r = 0.70 and 0.59 for 20-MST and 550-m run, respectively). Adjusting for body fatness and maturity levels in a multivariate regression analysis increased the associations between the field tests and VO2max (r = 0.73 for 20-MST and 0.65 for 550-m). We may conclude that both the 20-MST and the 550-m distance run are valid field tests of cardiorespiratory fitness in New Zealand 8-13 year old children and incorporating body fatness and maturity levels explains an additional 5-7% of the variance.

Effects of Ramadan intermittent fasting on middle-distance running performance in well-trained runners.

PubMed

Brisswalter, Jeanick; Bouhlel, Ezzedine; Falola, Jean Marie; Abbiss, Christopher R; Vallier, Jean Marc; Hausswirth, Christophe; Hauswirth, Christophe

2011-09-01

To assess whether Ramadan intermittent fasting (RIF) affects 5000-m running performance and physiological parameters classically associated with middle-distance performance. Two experimental groups (Ramadan fasting, n = 9, vs control, n = 9) participated in 2 experimental sessions, one before RIF and the other at the last week of fasting. For each session, subjects completed 4 tests in the same order: a maximal running test, a maximal voluntary contraction (MVC) of knee extensor, 2 rectangular submaximal exercises on treadmill for 6 minutes at an intensity corresponding to the first ventilatory threshold (VT1), and a running performance test (5000 m). Eighteen, well-trained, middle-distance runners. Maximal oxygen consumption, MVC, running performance, running efficiency, submaximal VO(2) kinetics parameters (VO(2), VO(2)b, time constant τ, and amplitude A1) and anthropometric parameters were recorded or calculated. At the end of Ramadan fasting, a decrease in MVC was observed (-3.2%; P < 0.00001; η, 0.80), associated with an increase in the time constant of oxygen kinetics (+51%; P < 0.00007; η, 0.72) and a decrease in performance (-5%; P < 0.0007; η, 0.51). No effect was observed on running efficiency or maximal aerobic power. These results suggest that Ramadan changes in muscular performance and oxygen kinetics could affect performance during middle-distance events and need to be considered to choose training protocols during RIF.

Self-Motion Perception during Locomotor Recalibration: More than Meets the Eye

ERIC Educational Resources Information Center

Durgin, Frank H.; Pelah, Adar; Fox, Laura F.; Lewis, Jed; Kane, Rachel; Walley, Katherine A.

2005-01-01

Do locomotor after effects depend specifically on visual feedback? In 7 experiments, 116 college students were tested, with closed eyes, at stationary running or at walking to a previewed target after adaptation, with closed eyes, to treadmill locomotion. Subjects showed faster inadvertent drift during stationary running and increased distance…

Effects of foot orthotics on running economy: methodological considerations.

PubMed

Burke, Jeanmarie R; Papuga, M Owen

2012-05-01

The purpose of the study was to collect preliminary data to address methodological considerations that may impact subject-specific reactions to foot orthotics during running. Six endurance-trained recreational runners recruited from a chiropractic college campus wore their preferred running shoes and then inserted either their custom-made orthotics during 1 testing session or their shoe-fitted insoles during the other testing session. Comfort perception was measured for each footwear condition. Measurements of oxygen consumption (VO2) at several moderate exercise intensities, to mimic recreational running, generated an individual's economy-of-running line. Predicted running velocity at VO(2max) (vVO2max) was calculated as an index of endurance performance. Lower extremity muscle activity was recorded. Descriptive statistics, a repeated-measures analysis of variance model, and a paired t test were used to document any systematic changes in running economy, lower extremity muscle activities, and vVO2max within and across subjects as a function of footwear conditions. Decreases in VO2 at several moderate exercise intensities (F((1,5)footwear) = 10.37, P = .023) and increases in vVO2max (t(5) = 4.20, P = .008) occurred in all 6 subjects while wearing their orthotic intervention vs their shoe-fitted insoles. There were no consistent changes in lower extremity muscle activity. Methodological decisions to use a sustained incremental exercise protocol at several moderate exercise intensities and to measure comfort perception of a custom-molded foot orthosis were effective at documenting systematic improvements in running economy among the 6 recreational runners tested. The development of a less physically demanding sustained exercise protocol is necessary to determine underlying neuromuscular mechanisms and/or clinical effectiveness of orthotic interventions. Copyright © 2012 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

Endurance capacity of mice selectively bred for high voluntary wheel running.

PubMed

Meek, Thomas H; Lonquich, Brian P; Hannon, Robert M; Garland, Theodore

2009-09-15

Mice from four lines bred for high voluntary wheel activity run approximately 3-fold more revolutions per day and have elevated maximal oxygen consumption during forced treadmill exercise, as compared with four unselected control (C) lines. We hypothesized that these high runner (HR) lines would have greater treadmill endurance-running capacity. Ninety-six mice from generation 49 were familiarized with running on a motorized treadmill for 3 days. On days 4 and 5, mice were given an incremental speed test (starting at 20 m min(-1), increased 1.5 m min(-1) every 2 min) and endurance was measured as the total time or distance run to exhaustion. Blood samples were taken to measure glucose and lactate concentrations at rest during the photophase, during peak nightly wheel running, and immediately following the second endurance test. Individual differences in endurance time were highly repeatable between days (r=0.79), and mice tended to run longer on the second day (paired t-test, P<0.0001). Blood glucose following the treadmill test was low for all animals ( approximately 53 mg dl(-1)) and lactate was high ( approximately 6.5 mmol l(-1)), suggesting that exhaustion occurred. The HR lines had significantly higher endurance than the C lines (1-tailed P<0.05), whether or not body mass was used as a covariate in the analysis. The relationship between line means for wheel running and treadmill endurance differed between the sexes, reinforcing previous studies that indicate sex-specific responses to selective breeding. HR mice appear to have a higher endurance capacity than reported in the literature for inbred strains of mice or transgenics intended to enhance endurance.

Effects of chronic nitric oxide synthase inhibition on V'O2max and exercise capacity in mice.

PubMed

Wojewoda, M; Przyborowski, K; Sitek, B; Zakrzewska, A; Mateuszuk, L; Zoladz, J A; Chlopicki, S

2017-03-01

Acute inhibition of NOS by L-NAME (N ω -nitro-L-arginine methyl ester) is known to decrease maximal oxygen consumption (V'O 2max ) and impair maximal exercise capacity, whereas the effects of chronic L-NAME treatment on V'O 2max and exercise performance have not been studied so far. In this study, we analysed the effect of L-NAME treatment, (LN2 and LN12, respectively) on V'O 2max and exercise capacity (in maximal incremental running and prolonged sub-maximal incremental running tests), systemic NO bioavailability (plasma nitrite (NO 2 - ) and nitrate (NO 3 - )) and prostacyclin (PGI 2 ) production in C57BL6/J mice. Mice treated with L-NAME for 2 weeks (LN2) displayed higher V'O 2max and better running capacity than age-matched control mice. In LN2 mice, NO bioavailability was preserved, as evidenced by maintained NO 2 - plasma concentration. PGI 2 production was activated (increased 6-keto-PGF 1α plasma concentration) and the number of circulating erythrocytes (RBC) and haemoglobin concentration were increased. In mice treated with L-NAME for 12 weeks (LN12), NO bioavailability was decreased (lower NO 2 - plasma concentration), and 6-keto-PGF 1α plasma concentration and RBC number were not elevated compared to age-matched control mice. However, LN12 mice still performed better during the maximal incremental running test despite having lower V'O 2max . Interestingly, the LN12 mice showed poorer running capacity during the prolonged sub-maximal incremental running test. To conclude, short-term (2 weeks) but not long-term (12 weeks) treatment with L-NAME activated robust compensatory mechanisms involving preservation of NO2- plasma concentration, overproduction of PGI 2 and increased number of RBCs, which might explain the fully preserved exercise capacity despite the inhibition of NOS.

Enhanced aerobic exercise performance in women by a combination of three mineral Chelates plus two conditionally essential nutrients.

PubMed

DiSilvestro, Robert A; Hart, Staci; Marshall, Trisha; Joseph, Elizabeth; Reau, Alyssa; Swain, Carmen B; Diehl, Jason

2017-01-01

Certain essential and conditionally essential nutrients (CENs) perform functions involved in aerobic exercise performance. However, increased intake of such nutrient combinations has not actually been shown to improve such performance. For 1 mo, aerobically fit, young adult women took either a combination of 3 mineral glycinate complexes (daily dose: 36 mg iron, 15 mg zinc, and 2 mg copper) + 2 CENs (daily dose: 2 g carnitine and 400 mg phosphatidylserine), or the same combination with generic mineral complexes, or placebo ( n  = 14/group). In Trial 1, before and after 1 mo, subjects were tested for 3 mile run time (primary outcome), followed by distance covered in 25 min on a stationary bike (secondary outcome), followed by a 90 s step test (secondary outcome). To test reproducibility of the run results, and to examine a lower dose of carnitine, a second trial was done. New subjects took either mineral glycinates + CENs (1 g carnitine) or placebo ( n  = 17/group); subjects were tested for pre- and post-treatment 3 mile run time (primary outcome). In Trial 1, the mineral glycinates + CENs decreased 3 mile run time (25.6 ± 2.4 vs 26.5 ± 2.3 min, p  < 0.05, paired t-test) increased stationary bike distance after 25 min (6.5 ± 0.6 vs 6.0 ± 0.8 miles, p  < 0.05, paired t-test), and increased steps in the step test (43.8 ± 4.8 vs 40.3 ± 6.4 steps, p < 0.05, paired t-test). The placebo significantly affected only the biking distance, but it was less than for the glycinates-CENs treatment (0.2 ± 0.4. vs 0.5 ± 0.1 miles, p < 0.05, ANOVA + Tukey). The generic minerals + CENs only significantly affected the step test (44.1 ± 5.2 vs 41.0 ± 5.9 steps, p < 0.05, paired t-test) In Trial 2, 3 mile run time was decreased for the mineral glycinates + CENs (23.9 ± 3.1 vs 24.7 ± 2.5, p  < 0.005, paired t-test), but not by the placebo. All changes for Test Formula II or III were high compared to placebo (1.9 to 4.9, Cohen's D), and high for Test Formula II vs I for running and biking (3.2 & 3.5, Cohen's D). In summary, a combination of certain mineral complexes plus two CENs improved aerobic exercise performance in fit young adult women.

40 CFR 86.134-96 - Running loss test.

Code of Federal Regulations, 2014 CFR

2014-07-01

... running loss test procedure as approved for a specific vehicle. (4) High-altitude testing. For testing... 40 Protection of Environment 19 2014-07-01 2014-07-01 false Running loss test. 86.134-96 Section... Heavy-Duty Vehicles; Test Procedures § 86.134-96 Running loss test. (a) Overview. Gasoline- and methanol...

Acute changes in foot strike pattern and cadence affect running parameters associated with tibial stress fractures.

PubMed

Yong, Jennifer R; Silder, Amy; Montgomery, Kate L; Fredericson, Michael; Delp, Scott L

2018-05-18

Tibial stress fractures are a common and debilitating injury that occur in distance runners. Runners may be able to decrease tibial stress fracture risk by adopting a running pattern that reduces biomechanical parameters associated with a history of tibial stress fracture. The purpose of this study was to test the hypothesis that converting to a forefoot striking pattern or increasing cadence without focusing on changing foot strike type would reduce injury risk parameters in recreational runners. Running kinematics, ground reaction forces and tibial accelerations were recorded from seventeen healthy, habitual rearfoot striking runners while running in their natural running pattern and after two acute retraining conditions: (1) converting to forefoot striking without focusing on cadence and (2) increasing cadence without focusing on foot strike. We found that converting to forefoot striking decreased two risk factors for tibial stress fracture: average and peak loading rates. Increasing cadence decreased one risk factor: peak hip adduction angle. Our results demonstrate that acute adaptation to forefoot striking reduces different injury risk parameters than acute adaptation to increased cadence and suggest that both modifications may reduce the risk of tibial stress fractures. Copyright © 2018 Elsevier Ltd. All rights reserved.

Time-Motion Analysis of Four Automated Systems for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae by Nucleic Acid Amplification Testing.

PubMed

Williams, James A; Eddleman, Laura; Pantone, Amy; Martinez, Regina; Young, Stephen; Van Der Pol, Barbara

2014-08-01

Next-generation diagnostics for Chlamydia trachomatis and Neisseria gonorrhoeae are available on semi- or fully-automated platforms. These systems require less hands-on time than older platforms and are user friendly. Four automated systems, the ABBOTT m2000 system, Becton Dickinson Viper System with XTR Technology, Gen-Probe Tigris DTS system, and Roche cobas 4800 system, were evaluated for total run time, hands-on time, and walk-away time. All of the systems evaluated in this time-motion study were able to complete a diagnostic test run within an 8-h work shift, instrument setup and operation were straightforward and uncomplicated, and walk-away time ranged from approximately 90 to 270 min in a head-to-head comparison of each system. All of the automated systems provide technical staff with increased time to perform other tasks during the run, offer easy expansion of the diagnostic test menu, and have the ability to increase specimen throughput. © 2013 Society for Laboratory Automation and Screening.

Effectiveness of Start to Run, a 6-week training program for novice runners, on increasing health-enhancing physical activity: a controlled study

PubMed Central

2013-01-01

Background The use of the organized sports sector as a setting for health-promotion is a relatively new strategy. In the past few years, different countries have been investing resources in the organized sports sector for promoting health-enhancing physical activity. In the Netherlands, National Sports Federations were funded to develop and implement “easily accessible” sporting programs, aimed at the least active population groups. Start to Run, a 6-week training program for novice runners, developed by the Dutch Athletics Organization, is one of these programs. In this study, the effects of Start to Run on health-enhancing physical activity were investigated. Methods Physical activity levels of Start to Run participants were assessed by means of the Short QUestionnaire to ASsess Health-enhancing physical activity (SQUASH) at baseline, immediately after completing the program and six months after baseline. A control group, matched for age and sex, was assessed at baseline and after six months. Compliance with the Dutch physical activity guidelines was the primary outcome measure. Secondary outcome measures were the total time spent in physical activity and the time spent in each physical activity intensity category and domain. Changes in physical activity within groups were tested with paired t-tests and McNemar tests. Changes between groups were examined with multiple linear and logistic regression analyses. Results In the Start to Run group, the percentage of people who met the Dutch Norm for Health-enhancing Physical Activity, Fit-norm and Combi-norm increased significantly, both in the short- and longer-term. In the control group, no significant changes in physical activity were observed. When comparing results between groups, significantly more Start to Run participants compared with control group participants were meeting the Fit-norm and Combi-norm after six months. The differences in physical activity between groups in favor of the Start to Run group could be explained by an increase in the time spent in vigorous-intensity activities and sports activities. Conclusions Start to Run positively influences levels of health-enhancing physical activity of participants, both in the short- and longer-term. Based on these results, the use of the organized sports sector as a setting to promote health-enhancing physical activity seems promising. PMID:23898920

Running Injuries in the Participants of Ljubljana Marathon.

PubMed

Vitez, Luka; Zupet, Petra; Zadnik, Vesna; Drobnič, Matej

2017-10-01

The aim of our study was to determine the self-reported incidence and prevalence of running-related injuries among participants of the 18 th Ljubljana Marathon, and to identify risk factors for their occurrence. A customized questionnaire was distributed over registration. Independent samples of t-test and chi-square test were used to calculate the differences in risk factors occurrence in the injured and non-injured group. Factors which appeared significantly more frequently in the injured group were included further into multiple logistic regression analysis. The reported lifetime running injury (absence >2 weeks) incidence was: 46% none, 47% rarely, 4% occasionally, and 2% often. Most commonly injured body regions were: knee (30%), ankle and Achilles' tendon (24%), foot (15%), and calf (12%). Male gender, running history of 1-3 years, and history of previous injuries were risk factors for life-time running injury. In the season preceding the event, 65% of participants had not experienced any running injuries, 19% of them reported minor problems (max 2 weeks absenteeism), but 10% and 7% suffered from moderate (absence 3-4 weeks) or major (more than 4 weeks pause) injuries. BMI was identified as the solely risk factor. This self-reported study revealed a 53% lifetime prevalence of running-related injuries, with the predominate involvement of knee, ankle and Achilles' tendon. One out of three recreational runners experienced at least one minor running injury per season. It seems that male gender, short running experience, previous injury, and BMI do increase the probability for running-related injuries.

40 CFR 86.134-96 - Running loss test.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Running loss test. 86.134-96 Section... Heavy-Duty Vehicles; Test Procedures § 86.134-96 Running loss test. (a) Overview. Gasoline- and methanol-fueled vehicles are to be tested for running loss emissions during simulated high-temperature urban...

40 CFR 86.134-96 - Running loss test.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Running loss test. 86.134-96 Section... Heavy-Duty Vehicles; Test Procedures § 86.134-96 Running loss test. (a) Overview. Gasoline- and methanol-fueled vehicles are to be tested for running loss emissions during simulated high-temperature urban...

40 CFR 86.134-96 - Running loss test.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Running loss test. 86.134-96 Section... Heavy-Duty Vehicles; Test Procedures § 86.134-96 Running loss test. (a) Overview. Gasoline- and methanol-fueled vehicles are to be tested for running loss emissions during simulated high-temperature urban...

40 CFR 86.134-96 - Running loss test.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Running loss test. 86.134-96 Section... Heavy-Duty Vehicles; Test Procedures § 86.134-96 Running loss test. (a) Overview. Gasoline- and methanol-fueled vehicles are to be tested for running loss emissions during simulated high-temperature urban...

Exercise Intensity-Dependent Effects on Cognitive Control Function during and after Acute Treadmill Running in Young Healthy Adults

PubMed Central

Wohlwend, Martin; Olsen, Alexander; Håberg, Asta K.; Palmer, Helen S.

2017-01-01

The idea that physical activity differentially impacts upon performance of various cognitive tasks has recently gained increased interest. However, our current knowledge about how cognition is altered by acute physical activity is incomplete. To measure how different intensity levels of physical activity affect cognition during and after 1 bout of physical activity, 30 healthy, young participants were randomized to perform a not-X continuous performance test (CPT) during low (LI)- and moderate intensity (MI) running. The same participants were subsequently randomized to perform the not-X CPT post LI, MI, and high intensity (HI) running. In addition, exercise related mood changes were assessed through a self-report measure pre and post running at LI, MI, and HI. Results showed worsening of performance accuracy on the not-X CPT during one bout of moderate compared to low intensity running. Post running, there was a linear decrease in reaction time with increasing running intensity and no change in accuracy or mood. The decreased reaction times post HI running recovered back to baseline within 20 min. We conclude that accuracy is acutely deteriorated during the most straining physical activity while a transient intensity-dependent enhancement of cognitive control function is present following physical activity. PMID:28377735

Adding Weather to Wargames

DTIC Science & Technology

2007-01-01

Aid (IWEDA) we developed techniques that allowed significant improvement in weather effects and impacts for wargames. TAWS was run for numerous and...found that the wargame realism was increased without impacting the run time. While these techniques are applicable to wargames in general, we tested...them by incorporation into the Advanced Warfighting Simulation (AWARS) model. AWARS was modified to incorporate weather impacts upon sensor

Reduced wheel running and blunted effects of voluntary exercise in LPA1-null mice: The importance of assessing the amount of running in transgenic mice studies

PubMed Central

Castilla-Ortega, Estela; Rosell-Valle, Cristina; Blanco, Eduardo; Pedraza, Carmen; Chun, Jerold; de Fonseca, Fernando Rodríguez; Estivill-Torrús, Guillermo; Santín, Luis J.

2014-01-01

This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of free wheel running and were tested for open-field behavior and adult hippocampal neurogenesis (cell proliferation, immature neurons, cell survival). Running decreased anxiety-like behavior in both genotypes but increased exploration only in the normal mice. While running affected all neurogenesis-related measures in normal mice (especially in the suprapyramidal blade of the dentate gyrus), only a moderate increase in cell survival was found in the mutants. Importantly, the LPA1-nulls showed notably reduced running. Analysis suggested that defective running in the LPA1-null mice could contribute to explain the scarce benefit of the voluntary exercise treatment. On the other hand, a literature review revealed that voluntary exercise is frequently used to modulate behavior and the hippocampus in transgenic mice, but half of the studies did not assess the quantity of running, overlooking any potential running impairments. This study adds evidence to the relevance of the quantity of exercise performed, emphasizing the importance of its assessment in transgenic mice research. PMID:24055600

Carbon dioxide emissions, GDP, energy use, and population growth: a multivariate and causality analysis for Ghana, 1971-2013.

PubMed

Asumadu-Sarkodie, Samuel; Owusu, Phebe Asantewaa

2016-07-01

In this study, the relationship between carbon dioxide emissions, GDP, energy use, and population growth in Ghana was investigated from 1971 to 2013 by comparing the vector error correction model (VECM) and the autoregressive distributed lag (ARDL). Prior to testing for Granger causality based on VECM, the study tested for unit roots, Johansen's multivariate co-integration and performed a variance decomposition analysis using Cholesky's technique. Evidence from the variance decomposition shows that 21 % of future shocks in carbon dioxide emissions are due to fluctuations in energy use, 8 % of future shocks are due to fluctuations in GDP, and 6 % of future shocks are due to fluctuations in population. There was evidence of bidirectional causality running from energy use to GDP and a unidirectional causality running from carbon dioxide emissions to energy use, carbon dioxide emissions to GDP, carbon dioxide emissions to population, and population to energy use. Evidence from the long-run elasticities shows that a 1 % increase in population in Ghana will increase carbon dioxide emissions by 1.72 %. There was evidence of short-run equilibrium relationship running from energy use to carbon dioxide emissions and GDP to carbon dioxide emissions. As a policy implication, the addition of renewable energy and clean energy technologies into Ghana's energy mix can help mitigate climate change and its impact in the future.

Revisiting the emissions-energy-trade nexus: evidence from the newly industrializing countries.

PubMed

Ahmed, Khalid; Shahbaz, Muhammad; Kyophilavong, Phouphet

2016-04-01

This paper applies Pedroni's panel cointegration approach to explore the causal relationship between trade openness, carbon dioxide emissions, energy consumption, and economic growth for the panel of newly industrialized economies (i.e., Brazil, India, China, and South Africa) over the period of 1970-2013. Our panel cointegration estimation results found majority of the variables cointegrated and confirm the long-run association among the variables. The Granger causality test indicates bidirectional causality between carbon dioxide emissions and energy consumption. A unidirectional causality is found running from trade openness to carbon dioxide emission and energy consumption and economic growth to carbon dioxide emissions. The results of causality analysis suggest that the trade liberalization in newly industrialized economies induces higher energy consumption and carbon dioxide emissions. Furthermore, the causality results are checked using an innovative accounting approach which includes forecast-error variance decomposition test and impulse response function. The long-run coefficients are estimated using fully modified ordinary least square (FMOLS) method, and results conclude that the trade openness and economic growth reduce carbon dioxide emissions in the long run. The results of FMOLS test sound the existence of environmental Kuznets curve hypothesis. It means that trade liberalization induces carbon dioxide emission with increased national output, but it offsets that impact in the long run with reduced level of carbon dioxide emissions.

Interval training at 95% and 100% of the velocity at VO2 max: effects on aerobic physiological indexes and running performance.

PubMed

Denadai, Benedito S; Ortiz, Marcelo J; Greco, Camila C; de Mello, Marco T

2006-12-01

The objective of this study was to analyze the effect of two different high-intensity interval training (HIT) programs on selected aerobic physiological indices and 1500 and 5000 m running performance in well-trained runners. The following tests were completed (n=17): (i) incremental treadmill test to determine maximal oxygen uptake (VO2 max), running velocity associated with VO2 max (vVO2 max), and the velocity corresponding to 3.5 mmol/L of blood lactate concentration (vOBLA); (ii) submaximal constant-intensity test to determine running economy (RE); and (iii) 1500 and 5000 m time trials on a 400 m track. Runners were then randomized into 95% vVO2 max or 100% vVO2 max groups, and undertook a 4 week training program consisting of 2 HIT sessions (performed at 95% or 100% vVO2 max, respectively) and 4 submaximal run sessions per week. Runners were retested on all parameters at the completion of the training program. The VO2 max values were not different after training for both groups. There was a significant increase in post-training vVO2 max, RE, and 1500 m running performance in the 100% vVO2 max group. The vOBLA and 5000 m running performance were significantly higher after the training period for both groups. We conclude that vOBLA and 5000 m running performance can be significantly improved in well-trained runners using a 4 week training program consisting of 2 HIT sessions (performed at 95% or 100% vVO2 max) and 4 submaximal run sessions per week. However, the improvement in vVO2 max, RE, and 1500 m running performance seems to be dependent on the HIT program at 100% vVO2 max.

Physical exercises on a bicycle-ergometer and running track to prevent hypodynamia in workers of intellectual labor

NASA Technical Reports Server (NTRS)

Vasilyeva, V. V.; Korableva, Y. N.; Trunin, V. V.

1980-01-01

A program of exercises was developed and tested, consisting of a 12 minute session on a variable load bicycle ergometer and a 10-11 min. run with brief stretching and resting sessions between. Physical performance capacity was measured before, during, and after the period of the experiment and physical exams conducted. After a 4 month test period involving 30 men, aged 25-35, the program was found to be successful in increasing physical performance capacity. The PWC170 increased an average of 22 percent and maximum oxygen consumption 14 percent. Arterial pressure dropped (120/75 to 114/68), vital capacity of lungs increased by 6 percent, strength of respiratory muscles by 8.8 percent, duration of respiratory delay by 18 percent. Duration of cardiac cycles increased, stress index decreased. Cardiac contraction rate 2 minutes after work on the ergometer decreased from 118 to 102 bt/min.

Running Injuries in the Participants of Ljubljana Marathon

PubMed Central

Vitez, Luka; Zupet, Petra; Zadnik, Vesna; Drobnič, Matej

2017-01-01

Abstract Introduction The aim of our study was to determine the self-reported incidence and prevalence of running-related injuries among participants of the 18th Ljubljana Marathon, and to identify risk factors for their occurrence. Methods A customized questionnaire was distributed over registration. Independent samples of t-test and chi-square test were used to calculate the differences in risk factors occurrence in the injured and non-injured group. Factors which appeared significantly more frequently in the injured group were included further into multiple logistic regression analysis. Results The reported lifetime running injury (absence >2 weeks) incidence was: 46% none, 47% rarely, 4% occasionally, and 2% often. Most commonly injured body regions were: knee (30%), ankle and Achilles’ tendon (24%), foot (15%), and calf (12%). Male gender, running history of 1-3 years, and history of previous injuries were risk factors for life-time running injury. In the season preceding the event, 65% of participants had not experienced any running injuries, 19% of them reported minor problems (max 2 weeks absenteeism), but 10% and 7% suffered from moderate (absence 3-4 weeks) or major (more than 4 weeks pause) injuries. BMI was identified as the solely risk factor. Conclusions This self-reported study revealed a 53% lifetime prevalence of running-related injuries, with the predominate involvement of knee, ankle and Achilles’ tendon. One out of three recreational runners experienced at least one minor running injury per season. It seems that male gender, short running experience, previous injury, and BMI do increase the probability for running-related injuries. PMID:29062393

Responding for sucrose and wheel-running reinforcement: effect of body weight manipulation.

PubMed

Belke, Terry W

2004-02-27

As body weight increases, the excitatory strength of a stimulus signaling an opportunity to run should weaken to a greater degree than that of a stimulus signaling an opportunity to eat. To test this hypothesis, six male albino Wistar rats were placed in running wheels and exposed to a fixed interval 30-s schedule that produced either a drop of 15% sucrose solution or the opportunity to run for 15s as reinforcing consequences for lever pressing. Each reinforcer type was signaled by a different stimulus. The effect of varying body weight on responding maintained by these two reinforcers was investigated by systematically increasing and decreasing post-session food amounts. The initial body weight was 335 g. Body weights were increased to approximately 445 g and subsequently returned to 335 g. As body weight increased, overall and local lever-pressing rates decreased while post-reinforcement pauses lengthened. Analysis of post-reinforcement pauses and local lever-pressing rates in terms of transitions between successive reinforcers revealed that local response rates in the presence of stimuli signaling upcoming wheel and sucrose reinforcers were similarly affected. However, pausing in the presence of the stimulus signaling a wheel-running reinforcer lengthened to a greater extent than did pausing in the presence of the stimulus signaling sucrose. This result suggests that as body weight approaches ad-lib levels, the likelihood of initiation of responding to obtain an opportunity to run approaches zero and the animal "rejects" the opportunity to run in a manner similar to the rejection of less preferred food items in studies of food selectivity.

49 CFR 238.319 - Running brake test.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Running brake test. 238.319 Section 238.319... Requirements for Tier I Passenger Equipment § 238.319 Running brake test. (a) As soon as conditions safely permit, a running brake test shall be performed on each passenger train after the train has received, or...

49 CFR 238.319 - Running brake test.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Running brake test. 238.319 Section 238.319... Requirements for Tier I Passenger Equipment § 238.319 Running brake test. (a) As soon as conditions safely permit, a running brake test shall be performed on each passenger train after the train has received, or...

Are smokers rational addicts? Empirical evidence from the Indonesian Family Life Survey

PubMed Central

2011-01-01

Background Indonesia is one of the largest consumers of tobacco in the world, however there has been little work done on the economics addiction of tobacco. This study provides an empirical test of a rational addiction (henceforth RA) hypothesis of cigarette demand in Indonesia. Methods Four estimators (OLS, 2SLS, GMM, and System-GMM) were explored to test the RA hypothesis. The author adopted several diagnostics tests to select the best estimator to overcome econometric problems faced in presence of the past and future cigarette consumption (suspected endogenous variables). A short-run and long-run price elasticities of cigarettes demand was then calculated. The model was applied to individuals pooled data derived from three-waves a panel of the Indonesian Family Life Survey spanning the period 1993-2000. Results The past cigarette consumption coefficients turned out to be a positive with a p-value < 1%, implying that cigarettes indeed an addictive goods. The rational addiction hypothesis was rejected in favour of myopic ones. The short-run cigarette price elasticity for male and female was estimated to be-0.38 and -0.57, respectively, and the long-run one was -0.4 and -3.85, respectively. Conclusions Health policymakers should redesign current public health campaign against cigarette smoking in the country. Given the demand for cigarettes to be more prices sensitive for the long run (and female) than the short run (and male), an increase in the price of cigarettes could lead to a significant fall in cigarette consumption in the long run rather than as a constant source of government revenue. PMID:21345229

Beneficial effects of fluoxetine, reboxetine, venlafaxine, and voluntary running exercise in stressed male rats with anxiety- and depression-like behaviors.

PubMed

Lapmanee, Sarawut; Charoenphandhu, Jantarima; Charoenphandhu, Narattaphol

2013-08-01

Rodents exposed to mild but repetitive stress may develop anxiety- and depression-like behaviors. Whether this stress response could be alleviated by pharmacological treatments or exercise interventions, such as wheel running, was unknown. Herein, we determined anxiety- and depression-like behaviors in restraint stressed rats (2h/day, 5 days/week for 4 weeks) subjected to acute diazepam treatment (30min prior to behavioral test), chronic treatment with fluoxetine, reboxetine or venlafaxine (10mg/kg/day for 4 weeks), and/or 4-week voluntary wheel running. In elevated plus-maze (EPM) and forced swimming tests (FST), stressed rats spent less time in the open arms and had less swimming duration than the control rats, respectively, indicating the presence of anxiety- and depression-like behaviors. Stressed rats also developed learned fear as evaluated by elevated T-maze test (ETM). Although wheel running could reduce anxiety-like behaviors in both EPM and ETM, only diazepam was effective in the EPM, while fluoxetine, reboxetine, and venlafaxine were effective in the ETM. Fluoxetine, reboxetine, and wheel running, but not diazepam and venlafaxine, also reduced depression-like behavior in FST. Combined pharmacological treatment and exercise did not further reduce anxiety-like behavior in stressed rats. However, stressed rats treated with wheel running plus reboxetine or venlafaxine showed an increase in climbing duration in FST. In conclusion, regular exercise (voluntary wheel running) and pharmacological treatments, especially fluoxetine and reboxetine, could alleviate anxiety- and depression-like behaviors in stressed male rats. Copyright © 2013 Elsevier B.V. All rights reserved.

Compression socks and functional recovery following marathon running: a randomized controlled trial.

PubMed

Armstrong, Stuart A; Till, Eloise S; Maloney, Stephen R; Harris, Gregory A

2015-02-01

Compression socks have become a popular recovery aid for distance running athletes. Although some physiological markers have been shown to be influenced by wearing these garments, scant evidence exists on their effects on functional recovery. This research aims to shed light onto whether the wearing of compression socks for 48 hours after marathon running can improve functional recovery, as measured by a timed treadmill test to exhaustion 14 days following marathon running. Athletes (n = 33, age, 38.5 ± 7.2 years) participating in the 2012 Melbourne, 2013 Canberra, or 2013 Gold Coast marathons were recruited and randomized into the compression sock or placebo group. A graded treadmill test to exhaustion was performed 2 weeks before and 2 weeks after each marathon. Time to exhaustion, average and maximum heart rates were recorded. Participants were asked to wear their socks for 48 hours immediately after completion of the marathon. The change in treadmill times (seconds) was recorded for each participant. Thirty-three participants completed the treadmill protocols. In the compression group, average treadmill run to exhaustion time 2 weeks after the marathon increased by 2.6% (52 ± 103 seconds). In the placebo group, run to exhaustion time decreased by 3.4% (-62 ± 130 seconds), P = 0.009. This shows a significant beneficial effect of compression socks on recovery compared with placebo. The wearing of below-knee compression socks for 48 hours after marathon running has been shown to improve functional recovery as measured by a graduated treadmill test to exhaustion 2 weeks after the event.

Are smokers rational addicts? Empirical evidence from the Indonesian Family Life Survey.

PubMed

Hidayat, Budi; Thabrany, Hasbullah

2011-02-23

Indonesia is one of the largest consumers of tobacco in the world, however there has been little work done on the economics addiction of tobacco. This study provides an empirical test of a rational addiction (henceforth RA) hypothesis of cigarette demand in Indonesia. Four estimators (OLS, 2SLS, GMM, and System-GMM) were explored to test the RA hypothesis. The author adopted several diagnostics tests to select the best estimator to overcome econometric problems faced in presence of the past and future cigarette consumption (suspected endogenous variables). A short-run and long-run price elasticities of cigarettes demand was then calculated. The model was applied to individuals pooled data derived from three-waves a panel of the Indonesian Family Life Survey spanning the period 1993-2000. The past cigarette consumption coefficients turned out to be a positive with a p-value < 1%, implying that cigarettes indeed an addictive goods. The rational addiction hypothesis was rejected in favour of myopic ones. The short-run cigarette price elasticity for male and female was estimated to be-0.38 and -0.57, respectively, and the long-run one was -0.4 and -3.85, respectively. Health policymakers should redesign current public health campaign against cigarette smoking in the country. Given the demand for cigarettes to be more prices sensitive for the long run (and female) than the short run (and male), an increase in the price of cigarettes could lead to a significant fall in cigarette consumption in the long run rather than as a constant source of government revenue.

Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy.

PubMed

Puolakkainen, Tero; Ma, Hongqian; Kainulainen, Heikki; Pasternack, Arja; Rantalainen, Timo; Ritvos, Olli; Heikinheimo, Kristiina; Hulmi, Juha J; Kiviranta, Riku

2017-01-19

Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle degeneration and also high incidence of fractures. The aim of our study was to test whether inhibition of activin receptor IIB ligands with or without exercise could improve bone strength in the mdx mouse model for DMD. Thirty-two mdx mice were divided to running and non-running groups and to receive either PBS control or soluble activin type IIB-receptor (ActRIIB-Fc) once weekly for 7 weeks. Treatment of mdx mice with ActRIIB-Fc resulted in significantly increased body and muscle weights in both sedentary and exercising mice. Femoral μCT analysis showed increased bone volume and trabecular number (BV/TV +80%, Tb.N +70%, P < 0.05) in both ActRIIB-Fc treated groups. Running also resulted in increased bone volume and trabecular number in PBS-treated mice. However, there was no significant difference in trabecular bone structure or volumetric bone mineral density between the ActRIIB-Fc and ActRIIB-Fc-R indicating that running did not further improve bone structure in ActRIIB-Fc-treated mice. ActRIIB-Fc increased bone mass also in vertebrae (BV/TV +20%, Tb.N +30%, P < 0.05) but the effects were more modest. The number of osteoclasts was decreased in histological analysis and the expression of several osteoblast marker genes was increased in ActRIIB-Fc treated mice suggesting decreased bone resorption and increased bone formation in these mice. Increased bone mass in femurs translated into enhanced bone strength in biomechanical testing as the maximum force and stiffness were significantly elevated in ActRIIB-Fc-treated mice. Our results indicate that treatment of mdx mice with the soluble ActRIIB-Fc results in a robust increase in bone mass, without any additive effect by voluntary running. Thus ActRIIB-Fc could be an attractive option in the treatment of musculoskeletal disorders.

Influence of running stride frequency in heart rate variability analysis during treadmill exercise testing.

PubMed

Bailón, Raquel; Garatachea, Nuria; de la Iglesia, Ignacio; Casajús, Jose Antonio; Laguna, Pablo

2013-07-01

The analysis and interpretation of heart rate variability (HRV) during exercise is challenging not only because of the nonstationary nature of exercise, the time-varying mean heart rate, and the fact that respiratory frequency exceeds 0.4 Hz, but there are also other factors, such as the component centered at the pedaling frequency observed in maximal cycling tests, which may confuse the interpretation of HRV analysis. The objectives of this study are to test the hypothesis that a component centered at the running stride frequency (SF) appears in the HRV of subjects during maximal treadmill exercise testing, and to study its influence in the interpretation of the low-frequency (LF) and high-frequency (HF) components of HRV during exercise. The HRV of 23 subjects during maximal treadmill exercise testing is analyzed. The instantaneous power of different HRV components is computed from the smoothed pseudo-Wigner-Ville distribution of the modulating signal assumed to carry information from the autonomic nervous system, which is estimated based on the time-varying integral pulse frequency modulation model. Besides the LF and HF components, the appearance is revealed of a component centered at the running SF as well as its aliases. The power associated with the SF component and its aliases represents 22±7% (median±median absolute deviation) of the total HRV power in all the subjects. Normalized LF power decreases as the exercise intensity increases, while normalized HF power increases. The power associated with the SF does not change significantly with exercise intensity. Consideration of the running SF component and its aliases is very important in HRV analysis since stride frequency aliases may overlap with LF and HF components.

Fitness Assessment Comparison Between the "Jackie Chan Action Run" Videogame, 1-Mile Run/Walk, and the PACER.

PubMed

Haddock, Bryan; Siegel, Shannon; Costa, Pablo; Jarvis, Sarah; Klug, Nicholas; Medina, Ernie; Wilkin, Linda

2012-06-01

The purpose of this study was to examine whether a correlation existed among the scores of the "Jackie Chan Studio Fitness(™) Action Run" active videogame (XaviX(®), SSD Company, Ltd., Kusatsu, Japan), the 1-mile run/walk, and Progressive Aerobic Cardiovascular Endurance Run (PACER) aerobic fitness tests of the FITNESSGRAM(®) (The Cooper Institute, Dallas, TX) in order to provide a potential alternative testing method for days that are not environmentally desirable for outdoor testing. Participants were a convenience sample from physical education classes of students between the ages of 10 and 15 years. Participants (n=108) were randomly assigned to one of three groups with the only difference being the order of testing. The tests included the "Jackie Chan Action Run" active videogame, the 1-mile run/walk, and the PACER. Testing occurred on three different days during the physical education class. Rating of perceived exertion (RPE) was reported. Significant correlations (r=-0.598 to 0.312) were found among the three aerobic fitness tests administered (P<0.05). The RPE for the "Jackie Chan Action Run" was lower than the RPE for the 1-mile run/walk and the PACER (3.81±1.89, 5.93±1.77, and 5.71±2.14, respectively). The results suggest that the "Jackie Chan Action Run" test could be an alternative to the 1-mile run/walk and PACER, allowing physical education teachers to perform aerobic fitness testing in an indoor setting that requires less space. Also, children may be more willing to participate in the "Jackie Chan Action Run" based on the lower RPE.

FY 1993 report on aluminum-nitrate testing at the ETF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodman, M.D.D.; Wise, M.D.

1993-09-30

This report summarizes the progress of the Aluminum Nitrate Nonhydrate (ANN) testing program at the F/H-Area Effluent Treatment Facility (ETF) for Fiscal Year 1993. Three tests were conducted in the months of February, April, and September. The tests yielded data that validated earlier conclusions that the addition of ANN to non-routine feed has a positive effect on the performance of ETF`s submicron filtration unit. Performance was observed to increase from 30--309%, depending on the season. The data also supports SRTC`s earlier conclusion that an optimal aluminum concentration exists in the range of 30--40 ppm, and concentrations above this range beginmore » to retard filtration performance. A rudimentary mathematical model that would predict Stage 1 flux was also developed during FY93. The model allowed for a more concise comparison of filter test runs, as well as increase the efficiency of the testing program by allowing shorter test runs to be conducted. It is postulated that the model can be further optimized to include aluminum concentration and time of year as independent variables that determine Stage 1 flux. Such a model should unequivocally prove the merits of pretreating ETF`s wastewater with aluminum nitrate. To proceed with the development of the model, further testing is proposed with stringent control of the aluminum concentration in the feed. In order to account for seasonal effects, one test should be conducted each month for Fiscal Year 1994. High Level Waste Engineering requests permission to conduct these test runs according to the following schedule: conduct tests in even numbered months beginning with October with routine influent as it is collected from normal process sewer influents and conduct tests in odd numbered months beginning with November with non-routine feed from H-Retention Basin.« less

Effects of Performance Versus Game-Based Mobile Applications on Response to Exercise.

PubMed

Gillman, Arielle S; Bryan, Angela D

2016-02-01

Given the popularity of mobile applications (apps) designed to increase exercise participation, it is important to understand their effects on psychological predictors of exercise behavior. This study tested a performance feedback-based app compared to a game-based app to examine their effects on aspects of immediate response to an exercise bout. Twenty-eight participants completed a 30-min treadmill run while using one of two randomly assigned mobile running apps: Nike + Running, a performance-monitoring app which theoretically induces an associative, goal-driven state, or Zombies Run!, an app which turns the experience of running into a virtual reality game, theoretically inducing dissociation from primary exercise goals. The two conditions did not differ on primary motivational state outcomes; however, participants reported more associative attentional focus in the performance-monitoring app condition compared to more dissociative focus in the game-based app condition. Game-based and performance-tracking running apps may not have differential effects on goal motivation during exercise. However, game-based apps may help recreational exercisers dissociate from exercise more readily. Increasing the enjoyment of an exercise bout through the development of new and innovative mobile technologies is an important avenue for future research.

Linear and non-linear impact of Internet usage and financial deepening on electricity consumption for Turkey: empirical evidence from asymmetric causality.

PubMed

Faisal, Faisal; Tursoy, Turgut; Berk, Niyazi

2018-04-01

This study investigates the relationship between Internet usage, financial development, economic growth, capital and electricity consumption using quarterly data from 1993Q1 to 2014Q4. The integration order of the series is analysed using the structural break unit root test. The ARDL bounds test for cointegration in addition to the Bayer-Hanck (2013) combined cointegration test is applied to analyse the existence of cointegration among the variables. The study found strong evidence of a long-run relationship between the variables. The long-run results under the ARDL framework confirm the existence of an inverted U-shaped relationship between financial development and electricity consumption, not only in the long-run, but also in the short-run. The study also confirms the existence of a U-shaped relationship between Internet usage and electricity consumption; however, the effect is insignificant. Additionally, the influence of trade, capital and economic growth is examined in both the long run and short run (ARDL-ECM). Finally, the results of asymmetric causality suggest a positive shock in electricity consumption that has a positive causal impact on Internet usage. The authors recommend that the Turkish Government should direct financial institutions to moderate the investment in the ICT sector by advancing credits at lower cost for purchasing energy-efficient technologies. In doing so, the Turkish Government can increase productivity in order to achieve sustainable growth, while simultaneously reducing emissions to improve environmental quality.

Validity of the Nike+ device during walking and running.

PubMed

Kane, N A; Simmons, M C; John, D; Thompson, D L; Bassett, D R; Basset, D R

2010-02-01

We determined the validity of the Nike+ device for estimating speed, distance, and energy expenditure (EE) during walking and running. Twenty trained individuals performed a maximal oxygen uptake test and underwent anthropometric and body composition testing. Each participant was outfitted with a Nike+ sensor inserted into the shoe and an Apple iPod nano. They performed eight 6-min stages on the treadmill, including level walking at 55, 82, and 107 m x min(-1), inclined walking (82 m x min(-1)) at 5 and 10% grades, and level running at 134, 161, and 188 m x min(-1). Speed was measured using a tachometer and EE was measured by indirect calorimetry. Results showed that the Nike+ device overestimated the speed of level walking at 55 m x min(-1) by 20%, underestimated the speed of level walking at 107 m x min(-1) by 12%, but closely estimated the speed of level walking at 82 m x min(-1), and level running at all speeds (p<0.05). Similar results were found for distance. The Nike+ device overestimated the EE of level walking by 18-37%, but closely estimated the EE of level running (p<0.05). In conclusion the Nike+ in-shoe device provided reasonable estimates of speed and distance during level running at the three speeds tested in this study. However, it overestimated EE during level walking and it did not detect the increased cost of inclined locomotion.

Effect of added mass on treadmill performance and pulmonary function.

PubMed

Walker, Rachel E; Swain, David P; Ringleb, Stacie I; Colberg, Sheri R

2015-04-01

Military personnel engage in strenuous physical activity and load carriage. This study evaluated the role of body mass and of added mass on aerobic performance (uphill treadmill exercise) and pulmonary function. Performance on a traditional unloaded run test (4.8 km) was compared with performance on loaded tasks. Subjects performed an outdoor 4.8-km run and 4 maximal treadmill tests wearing loads of 0, 10, 20, and 30 kg. Subjects' pulmonary function (forced expired volume in 1 second [FEV1], forced vital capacity [FVC], and maximal voluntary ventilation [MVV]) was tested with each load, and peak values of heart rate, oxygen consumption ((Equation is included in full-text article.)), ventilation (VE), and respiratory exchange ratio (RER) were measured during each treadmill test. Performance on the 4.8-km run was correlated with treadmill performance, measured as time to exhaustion (TTE), with the strength of the correlation decreasing with load (r = 0.87 for 0 kg to 0.76 for 30 kg). Body mass was not correlated with TTE, other than among men with the 30-kg load (r = 0.48). During treadmill exercise, all peak responses other than RER decreased with load. Pulmonary function measures (FEV1, FVC, and MVV) decreased with load. Body mass was poorly correlated with treadmill performance, but added mass decreased performance. The decreased performance may be in part because of decreased pulmonary function. Unloaded 4.8-km run performance was correlated to unloaded uphill treadmill performance, but less so as load increased. Therefore, traditional run tests may not be an effective means of evaluating aerobic performance for military field operations.

Lower limb mechanics during moderate high-heel jogging and running in different experienced wearers.

PubMed

Fu, Fengqin; Zhang, Yan; Shu, Yang; Ruan, Guoqing; Sun, Jianjun; Baker, Julien S; Gu, Yaodong

2016-08-01

The aim of this study is to investigate the differences in lower limb kinematics and kinetics between experienced (EW) and inexperienced (IEW) moderate high-heel wearers during jogging and running. Eleven experienced female wearers of moderate high-heel shoes and eleven matched controls participated in jogging and running tests. A Vicon motion analysis system was used to capture kinematic data and a Kistler force platform was used to collect ground reaction force (GRF). There were no significant differences in jogging and running speed respectively. Compared with IEW, EW adopted larger stride length (SL) with lower stride frequency (SF) at each corresponding speed. During running, EW enlarged SL significantly while IEW increased both SL and SF significantly. Kinematic data showed that IEW had generally larger joint range of motion (ROM) and peak angles during stance phase. Speed effect was not obvious within IEW. EW exhibited a significantly increased maximal vertical GRF (Fz2) and vertical average loading rate (VALR) during running, which was potentially caused by overlong stride. These suggest that both EW and IEW are at high risk of joint injuries when running on moderate high heels. For wearers who have to do some running on moderate high heels, it is crucial to control joint stability and balance SL and SF consciously. Copyright © 2016 Elsevier B.V. All rights reserved.

The effect of muscle fatigue on in vivo tibial strains.

PubMed

Milgrom, Charles; Radeva-Petrova, Denitsa R; Finestone, Aharon; Nyska, Meir; Mendelson, Stephen; Benjuya, Nisim; Simkin, Ariel; Burr, David

2007-01-01

Stress fracture is a common musculoskeletal problem affecting athletes and soldiers. Repetitive high bone strains and strain rates are considered to be its etiology. The strain level necessary to cause fatigue failure of bone ex vivo is higher than the strains recorded in humans during vigorous physical activity. We hypothesized that during fatiguing exercises, bone strains may increase and reach levels exceeding those measured in the non-fatigued state. To test this hypothesis, we measured in vivo tibial strains, the maximum gastrocnemius isokinetic torque and ground reaction forces in four subjects before and after two fatiguing levels of exercise: a 2km run and a 30km desert march. Strains were measured using strain-gauged staples inserted percutaneously in the medial aspect of their mid-tibial diaphysis. There was a decrease in the peak gastrocnemius isokinetic torque of all four subjects' post-march as compared to pre-run (p=0.0001), indicating the presence of gastrocnemius muscle fatigue. Tension strains increased 26% post-run (p=0.002, 95 % confidence interval (CI) and 29% post-march (p=0.0002, 95% CI) as compared to the pre-run phase. Tension strain rates increased 13% post-run (p=0.001, 95% CI) and 11% post-march (p=0.009, 95% CI) and the compression strain rates increased 9% post-run (p=0.0004, 95% CI) and 17% post-march (p=0.0001, 95% CI). The fatigue state increases bone strains well above those recorded in rested individuals and may be a major factor in the stress fracture etiology.

Hot piston ring tests

NASA Technical Reports Server (NTRS)

Allen, David J.; Tomazic, William A.

1987-01-01

As part of the DOE/NASA Automotive Stirling Engine Project, tests were made at NASA Lewis Research Center to determine whether appendix gap losses could be reduced and Stirling engine performance increased by installing an additional piston ring near the top of each piston dome. An MTI-designed upgraded Mod I Automotive Stirling Engine was used. Unlike the conventional rings at the bottom of the piston, these hot rings operated in a high temperature environment (700 C). They were made of a high temperature alloy (Stellite 6B) and a high temperature solid lubricant coating (NASA Lewis-developed PS-200) was applied to the cylinder walls. Engine tests were run at 5, 10, and 15 MPa operating pressure over a range of operating speeds. Tests were run both with hot rings and without to provide a baseline for comparison. Minimum data to assess the potential of both the hot rings and high temperature low friction coating was obtained. Results indicated a slight increase in power and efficiency, an increase over and above the friction loss introduced by the hot rings. Seal leakage measurements showed a significant reduction. Wear on both rings and coating was low.

Kinematic and kinetic comparison of running in standard and minimalist shoes.

PubMed

Willy, Richard W; Davis, Irene S

2014-02-01

The purpose of this study was to determine whether running in a minimalist shoe results in a reduction in ground reaction forces and alters kinematics over standard shoe running. The secondary purpose of this study was to determine whether within-session accommodation to a novel minimalist shoe occurs. Subjects were 14 male, rearfoot striking runners who had never run in a minimalist shoe. Subjects were tested while running 3.35 m·s(-1) for 10 min on an instrumented treadmill in a minimalist and a standard shoe as three-dimensional lower extremity kinematics and kinetics were evaluated. Data were collected at minute 1 and then again after 10 min of running in both shoe conditions to evaluate accommodation to the shoe conditions. Shoe-time interactions were not found for any of the variables of interest. Minimalist shoe running resulted in no changes in step length (P = 0.967) or in step rate (P = 0.230). At footstrike, greater knee flexion (P = 0.001) and greater dorsiflexion angle (P = 0.025) were noted in the minimalist shoe. Vertical impact peak (P = 0.017) and average vertical loading rate (P < 0.000) were greater during minimalist shoe running. There were main effects of time as dorsiflexion angle decreased (P = 0.035), foot inclination at footstrike decreased (P = 0.048), and knee flexion at footstrike increased (P = 0.002), yet the vertical impact peak (P = 0.002) and average vertical loading rate (P < 0.000) increased. Running in a minimalist shoe appears to, at least in the short term, increase loading of the lower extremity over standard shoe running. The accommodation period resulted in less favorable landing mechanics in both shoes. These findings bring into question whether minimal shoes will provide enough feedback to induce an alteration that is similar to barefoot running.

Youth fitness testing: the effect of percentile-based evaluative feedback on intrinsic motivation.

PubMed

Whitehead, J R; Corbin, C B

1991-06-01

This study was a test of Deci and Ryan's (1985) cognitive evaluation theory in a fitness testing situation. More specifically, it was a test of Proposition 2 of that theory, which posits that external events that increase or decrease perceived competence will increase or decrease intrinsic motivation. Seventh and eighth grade schoolchildren (N = 105) volunteered for an experiment that was ostensibly to collect data on a new youth fitness test (the Illinois Agility Run). After two untimed practice runs, a specially adapted version of the Intrinsic Motivation Inventory (IMI) was administered as a pretest of intrinsic motivation. Two weeks later when subjects ran again, they were apparently electronically timed. In reality, the subjects were given bogus feedback. Subjects in a positive feedback condition were told their scores were above the 80th percentile, while those in a negative feedback condition were told their scores were below the 20th percentile. Those in a control condition received no feedback. The IMI was again administered to the subjects after their runs. Multivariate and subsequent univariate tests were significant for all four subscale dependent variables (perceived interest-enjoyment, competence, effort, and pressure-tension). Positive feedback enhanced all aspects of intrinsic motivation, whereas negative feedback decreased them. In a further test of cognitive evaluation theory, path analysis results supported the prediction that perceived competence would mediate changes in the other IMI subscales. Taken together, these results clearly support cognitive evaluation theory and also may have important implications regarding motivation for those who administer youth fitness tests.

Investigation of Storage Options for Scientific Computing on Grid and Cloud Facilities

NASA Astrophysics Data System (ADS)

Garzoglio, Gabriele

2012-12-01

In recent years, several new storage technologies, such as Lustre, Hadoop, OrangeFS, and BlueArc, have emerged. While several groups have run benchmarks to characterize them under a variety of configurations, more work is needed to evaluate these technologies for the use cases of scientific computing on Grid clusters and Cloud facilities. This paper discusses our evaluation of the technologies as deployed on a test bed at FermiCloud, one of the Fermilab infrastructure-as-a-service Cloud facilities. The test bed consists of 4 server-class nodes with 40 TB of disk space and up to 50 virtual machine clients, some running on the storage server nodes themselves. With this configuration, the evaluation compares the performance of some of these technologies when deployed on virtual machines and on “bare metal” nodes. In addition to running standard benchmarks such as IOZone to check the sanity of our installation, we have run I/O intensive tests using physics-analysis applications. This paper presents how the storage solutions perform in a variety of realistic use cases of scientific computing. One interesting difference among the storage systems tested is found in a decrease in total read throughput with increasing number of client processes, which occurs in some implementations but not others.

Investigation of storage options for scientific computing on Grid and Cloud facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garzoglio, Gabriele

In recent years, several new storage technologies, such as Lustre, Hadoop, OrangeFS, and BlueArc, have emerged. While several groups have run benchmarks to characterize them under a variety of configurations, more work is needed to evaluate these technologies for the use cases of scientific computing on Grid clusters and Cloud facilities. This paper discusses our evaluation of the technologies as deployed on a test bed at FermiCloud, one of the Fermilab infrastructure-as-a-service Cloud facilities. The test bed consists of 4 server-class nodes with 40 TB of disk space and up to 50 virtual machine clients, some running on the storagemore » server nodes themselves. With this configuration, the evaluation compares the performance of some of these technologies when deployed on virtual machines and on bare metal nodes. In addition to running standard benchmarks such as IOZone to check the sanity of our installation, we have run I/O intensive tests using physics-analysis applications. This paper presents how the storage solutions perform in a variety of realistic use cases of scientific computing. One interesting difference among the storage systems tested is found in a decrease in total read throughput with increasing number of client processes, which occurs in some implementations but not others.« less

Reduced wheel running and blunted effects of voluntary exercise in LPA1-null mice: the importance of assessing the amount of running in transgenic mice studies.

PubMed

Castilla-Ortega, Estela; Rosell-Valle, Cristina; Blanco, Eduardo; Pedraza, Carmen; Chun, Jerold; Rodríguez de Fonseca, Fernando; Estivill-Torrús, Guillermo; Santín, Luis J

2013-11-01

This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of free wheel running and were tested for open-field behavior and adult hippocampal neurogenesis (cell proliferation, immature neurons, cell survival). Running decreased anxiety-like behavior in both genotypes but increased exploration only in the normal mice. While running affected all neurogenesis-related measures in normal mice (especially in the suprapyramidal blade of the dentate gyrus), only a moderate increase in cell survival was found in the mutants. Importantly, the LPA1-nulls showed notably reduced running. Analysis suggested that defective running in the LPA1-null mice could contribute to explain the scarce benefit of the voluntary exercise treatment. On the other hand, a literature review revealed that voluntary exercise is frequently used to modulate behavior and the hippocampus in transgenic mice, but half of the studies did not assess the quantity of running, overlooking any potential running impairments. This study adds evidence to the relevance of the quantity of exercise performed, emphasizing the importance of its assessment in transgenic mice research. Copyright © 2013 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

The Effect of Training in Minimalist Running Shoes on Running Economy

PubMed Central

Ridge, Sarah T.; Standifird, Tyler; Rivera, Jessica; Johnson, A. Wayne; Mitchell, Ulrike; Hunter, Iain

2015-01-01

The purpose of this study was to examine the effect of minimalist running shoes on oxygen uptake during running before and after a 10-week transition from traditional to minimalist running shoes. Twenty-five recreational runners (no previous experience in minimalist running shoes) participated in submaximal VO2 testing at a self-selected pace while wearing traditional and minimalist running shoes. Ten of the 25 runners gradually transitioned to minimalist running shoes over 10 weeks (experimental group), while the other 15 maintained their typical training regimen (control group). All participants repeated submaximal VO2 testing at the end of 10 weeks. Testing included a 3 minute warm-up, 3 minutes of running in the first pair of shoes, and 3 minutes of running in the second pair of shoes. Shoe order was randomized. Average oxygen uptake was calculated during the last minute of running in each condition. The average change from pre- to post-training for the control group during testing in traditional and minimalist shoes was an improvement of 3.1 ± 15.2% and 2.8 ± 16.2%, respectively. The average change from pre- to post-training for the experimental group during testing in traditional and minimalist shoes was an improvement of 8.4 ± 7.2% and 10.4 ± 6.9%, respectively. Data were analyzed using a 2-way repeated measures ANOVA. There were no significant interaction effects, but the overall improvement in running economy across time (6.15%) was significant (p = 0.015). Running in minimalist running shoes improves running economy in experienced, traditionally shod runners, but not significantly more than when running in traditional running shoes. Improvement in running economy in both groups, regardless of shoe type, may have been due to compliance with training over the 10-week study period and/or familiarity with testing procedures. Key points Running in minimalist footwear did not result in a change in running economy compared to running in traditional footwear prior to 10 weeks of training. Both groups (control and experimental) showed an improvement in running economy in both types of shoes after 10 weeks of training. After transitioning to minimalist running shoes, running economy was not significantly different while running in traditional or minimalist footwear. PMID:26336352

The Effect of Training in Minimalist Running Shoes on Running Economy.

PubMed

Ridge, Sarah T; Standifird, Tyler; Rivera, Jessica; Johnson, A Wayne; Mitchell, Ulrike; Hunter, Iain

2015-09-01

The purpose of this study was to examine the effect of minimalist running shoes on oxygen uptake during running before and after a 10-week transition from traditional to minimalist running shoes. Twenty-five recreational runners (no previous experience in minimalist running shoes) participated in submaximal VO2 testing at a self-selected pace while wearing traditional and minimalist running shoes. Ten of the 25 runners gradually transitioned to minimalist running shoes over 10 weeks (experimental group), while the other 15 maintained their typical training regimen (control group). All participants repeated submaximal VO2 testing at the end of 10 weeks. Testing included a 3 minute warm-up, 3 minutes of running in the first pair of shoes, and 3 minutes of running in the second pair of shoes. Shoe order was randomized. Average oxygen uptake was calculated during the last minute of running in each condition. The average change from pre- to post-training for the control group during testing in traditional and minimalist shoes was an improvement of 3.1 ± 15.2% and 2.8 ± 16.2%, respectively. The average change from pre- to post-training for the experimental group during testing in traditional and minimalist shoes was an improvement of 8.4 ± 7.2% and 10.4 ± 6.9%, respectively. Data were analyzed using a 2-way repeated measures ANOVA. There were no significant interaction effects, but the overall improvement in running economy across time (6.15%) was significant (p = 0.015). Running in minimalist running shoes improves running economy in experienced, traditionally shod runners, but not significantly more than when running in traditional running shoes. Improvement in running economy in both groups, regardless of shoe type, may have been due to compliance with training over the 10-week study period and/or familiarity with testing procedures. Key pointsRunning in minimalist footwear did not result in a change in running economy compared to running in traditional footwear prior to 10 weeks of training.Both groups (control and experimental) showed an improvement in running economy in both types of shoes after 10 weeks of training.After transitioning to minimalist running shoes, running economy was not significantly different while running in traditional or minimalist footwear.

Higher Accuracy of the Lactate Minimum Test Compared to Established Threshold Concepts to Determine Maximal Lactate Steady State in Running.

PubMed

Wahl, Patrick; Zwingmann, Lukas; Manunzio, Christian; Wolf, Jacob; Bloch, Wilhelm

2018-05-18

This study evaluated the accuracy of the lactate minimum test, in comparison to a graded-exercise test and established threshold concepts (OBLA and mDmax) to determine running speed at maximal lactate steady state. Eighteen subjects performed a lactate minimum test, a graded-exercise test (2.4 m·s -1 start,+0.4 m·s -1 every 5 min) and 2 or more constant-speed tests of 30 min to determine running speed at maximal lactate steady state. The lactate minimum test consisted of an initial lactate priming segment, followed by a short recovery phase. Afterwards, the initial load of the subsequent incremental segment was individually determined and was increased by 0.1 m·s -1 every 120 s. Lactate minimum was determined by the lowest measured value (LM abs ) and by a third-order polynomial (LM pol ). The mean difference to maximal lactate steady state was+0.01±0.14 m·s -1 (LM abs ), 0.04±0.15 m·s -1 (LM pol ), -0.06±0.31 m·s 1 (OBLA) and -0.08±0.21 m·s 1 (mDmax). The intraclass correlation coefficient (ICC) between running velocity at maximal lactate steady state and LM abs was highest (ICC=0.964), followed by LM pol (ICC=0.956), mDmax (ICC=0.916) and OBLA (ICC=0.885). Due to the higher accuracy of the lactate minimum test to determine maximal lactate steady state compared to OBLA and mDmax, we suggest the lactate minimum test as a valid and meaningful concept to estimate running velocity at maximal lactate steady state in a single session for moderately up to well-trained athletes. © Georg Thieme Verlag KG Stuttgart · New York.

Experimental winter warming modifies thermal performance and primes acorn ants for warm weather.

PubMed

MacLean, Heidi J; Penick, Clint A; Dunn, Robert R; Diamond, Sarah E

2017-07-01

The frequency of warm winter days is increasing under global climate change, but how organisms respond to warmer winters is not well understood. Most studies focus on growing season responses to warming. Locomotor performance is often highly sensitive to temperature, and can determine fitness outcomes through a variety of mechanisms including resource acquisition and predator escape. As a consequence, locomotor performance, and its impacts on fitness, may be strongly affected by winter warming in winter-active species. Here we use the acorn ant, Temnothorax curvispinosus, to explore how thermal performance (temperature-driven plasticity) in running speed is influenced by experimental winter warming of 3-5°C above ambient in a field setting. We used running speed as a measure of performance as it is a common locomotor trait that influences acquisition of nest sites and food in acorn ants. Experimental winter warming significantly altered thermal performance for running speed at high (26 and 36°C) but not low test temperatures (6 and 16°C). Although we saw little differentiation in thermal performance at cooler test temperatures, we saw a marked increase in running speed at the hotter test temperatures for ants that experienced warmer winters compared with those that experienced cooler winters. Our results provide evidence that overwintering temperatures can substantially influence organismal performance, and suggest that we cannot ignore overwintering effects when forecasting organismal responses to environmental changes in temperature. Copyright © 2017 Elsevier Ltd. All rights reserved.

The effect of intermediate altitude on the Army Physical Fitness Test.

PubMed

Perry, M E; Browning, R J; Jackson, R; Meyer, J

1992-10-01

Official physical training records of personnel stationed at intermediate altitude (elevation 5,280 feet) for at least 1 year were reviewed to gauge the effect of altitude on 2-mile running performance. An average of 48 additional seconds (a 5% increase in time) was required to complete the run compared to sea-level values in the same subjects. Run times gradually diminished during the first 9 months of assignment to altitude before stability was established. These data indicate that acclimatization occurs over several months. Even with acclimatization, substantial loss of performance is associated with habitation at intermediate altitude.

[The effect of hypoxia preconditioning no binding activity of HIF-1 on the HRE with EPO in the hippocampus of mice].

PubMed

Shao, Guo; Zhou, Wei-Hua; Gao, Cui-Ying; Zhang, Ran; Lu, Guo-Wei

2007-02-01

To observe change of binding activity of HIF-1 with erythropoietin (EPO) hypoxia response element (HRE) in the hippocampus of mice preconditioned to hypoxia and explore relationship between the changes and the preconditioning. The hippocampus was removed from mice exposed to hypoxia for 0 run (control group), 1 run (H1 group) and 4 runs(H4 group). Electrophoretic mobility shift assays (EMSA), chromatin immunoprecipitation (ChIP)and real time PCR were used to detect the change of activity of HIF-1 on HRE of EPO. Both in vitro and in vivo binding tests showed that the HIF-1 DNA-binding activities were increased in group H1 and markedly increased in group H4. The increase of HIF-1 and HRE of EPO binding activities is thought be involved in hypoxic preconditioning.

The effect of pre-test carbohydrate ingestion on the anaerobic threshold, as determined by the lactate-minimum test.

PubMed

Rotstein, Arie; Dotan, Raffy; Zigel, Levana; Greenberg, Tally; Benyamini, Yael; Falk, Bareket

2007-12-01

The purpose of this study was to investigate the effect of pre-test carbohydrate (CHO) ingestion on anaerobic-threshold assessment using the lactate-minimum test (LMT). Fifteen competitive male distance runners capable of running 10 km in 33.5-43 min were used as subjects. LMT was performed following CHO (2x300 mL, 7% solution) or comparable placebo (Pl) ingestion, in a double-blind, randomized order. The LMT consisted of two high-intensity 1 min treadmill runs (17-21 km.h(-1)), followed by an 8 min recovery period. Subsequently, subjects performed 5 min running stages, incremented by 0.6 km.h(-1) and separated by 1 min blood-sampling intervals. Tests were terminated after 3 consecutive increases in blood-lactate concentration ([La]) had been observed. Finger-tip capillary blood was sampled for [La] and blood-glucose determination 30 min before the test's onset, during the recovery phase following the 2 high-intensity runs, and following each of the subsequent 5 min stages. Heart rate (HR) and rating of perceived exertion (RPE) were recorded after each stage. The lactate-minimum speed (LMS) was determined from the individual [La]-velocity plots and was considered reflective of the anaerobic threshold. Pre-test CHO ingestion had no effect on LMS (13.19+/-1.12 km.h(-1) vs. 13.17+/-1.08 km.h(-1) in CHO and Pl, respectively), nor on [La] and glucose concentration at that speed, or on HR and RPE responses. Pre-test CHO ingestion therefore does not affect LMS or the LMT-estimated anaerobic threshold.

Effect of training with and without a load on military fitness tests and marksmanship.

PubMed

Swain, David P; Ringleb, Stacie I; Naik, Dayanand N; Butowicz, Courtney M

2011-07-01

The purpose of this study was to determine whether military-style training performed while carrying a weighted vest and backpack (Load condition) resulted in superior training adaptations (specifically, changes in military fitness and marksmanship) than did more conventional training (No-Load condition). A total of 33 college-aged men and women (16 Load, 17 No-Load) completed all testing and 9 weeks of training (1 h·d, 4 d·wk). No-Load training consisted of military calisthenics, sprints, agility drills, and running. Load training was similar except that running was replaced with stair climbing, and Load increased across the 9 weeks to 20 kg for women and 30 kg for men. Pretraining and posttraining, all subjects performed an uphill treadmill test with full load to determine peak oxygen consumption (VO(2)peak), the marine physical fitness test (PFT) and combat fitness test (CFT) without load, other fitness tests, and an indoor marksmanship test using a laser-fitted carbine. The marksmanship test was performed with full load and done before and immediately after a 200-m shuttle run performed in 60 seconds. Both groups significantly improved their VO(2)peak, PFT, and CFT scores by similar amounts. Pretraining, shooting score decreased significantly after the 200-m run and then rapidly recovered, with no difference between groups. A similar, but nonsignificant, pattern in shooting scores was seen in both groups posttraining. In conclusion, loaded training did not produce measurable advantages compared with unloaded training in this population. A strenuous anaerobic challenge caused a temporary reduction in marksmanship.

Study Protocol: The influence of Running Therapy on executive functions and sleep of prisoners

PubMed Central

Meijers, Jesse; Harte, Joke; Meynen, Gerben; Cuijpers, Pim

2015-01-01

Background: Executive dysfunction appears to be related to increased recidivism. Of note is that sleep disturbances, which are highly prevalent in prisons, may attenuate executive functions. Thus, improving executive functions, either directly or indirectly through the improvement of sleep, may reduce recidivism. It is hypothesised that physical exercise, in the form of Running Therapy, has a direct positive effect on executive functions as well as an indirect effect through the improvement of sleep. Methods/Design: Seventy two (N = 72) detainees in various penitentiary institutions in the Netherlands will be recruited in this study. A baseline measurement, including six neuropsychological tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB), an assessment of sleep quality and duration using the Actiwatch (Actiwatch 2, Philips Respironics, Murrysville, PA, USA) and various other measurements will be administered before the start of the treatment. After 3 months of Running Therapy, participants will be assessed again with the same tests for neuropsychological and physical functioning. Primary outcomes are executive functioning and various sleep variables. Discussion: This study will be the first to investigate the possible influence of Running Therapy on the cognitive functioning, sleep and aggression in prisoners. PMID:26664703

Study Protocol: The influence of Running Therapy on executive functions and sleep of prisoners.

PubMed

Meijers, Jesse; Harte, Joke; Meynen, Gerben; Cuijpers, Pim

2015-01-01

Executive dysfunction appears to be related to increased recidivism. Of note is that sleep disturbances, which are highly prevalent in prisons, may attenuate executive functions. Thus, improving executive functions, either directly or indirectly through the improvement of sleep, may reduce recidivism. It is hypothesised that physical exercise, in the form of Running Therapy, has a direct positive effect on executive functions as well as an indirect effect through the improvement of sleep. Seventy two (N = 72) detainees in various penitentiary institutions in the Netherlands will be recruited in this study. A baseline measurement, including six neuropsychological tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB), an assessment of sleep quality and duration using the Actiwatch (Actiwatch 2, Philips Respironics, Murrysville, PA, USA) and various other measurements will be administered before the start of the treatment. After 3 months of Running Therapy, participants will be assessed again with the same tests for neuropsychological and physical functioning. Primary outcomes are executive functioning and various sleep variables. This study will be the first to investigate the possible influence of Running Therapy on the cognitive functioning, sleep and aggression in prisoners.

Wheel running in the wild.

PubMed

Meijer, Johanna H; Robbers, Yuri

2014-07-07

The importance of exercise for health and neurogenesis is becoming increasingly clear. Wheel running is often used in the laboratory for triggering enhanced activity levels, despite the common objection that this behaviour is an artefact of captivity and merely signifies neurosis or stereotypy. If wheel running is indeed caused by captive housing, wild mice are not expected to use a running wheel in nature. This however, to our knowledge, has never been tested. Here, we show that when running wheels are placed in nature, they are frequently used by wild mice, also when no extrinsic reward is provided. Bout lengths of running wheel behaviour in the wild match those for captive mice. This finding falsifies one criterion for stereotypic behaviour, and suggests that running wheel activity is an elective behaviour. In a time when lifestyle in general and lack of exercise in particular are a major cause of disease in the modern world, research into physical activity is of utmost importance. Our findings may help alleviate the main concern regarding the use of running wheels in research on exercise.

[Impacts on skin blood flow under moving cupping along meridians in different directions].

PubMed

Tian, Yu-Ying; Wang, Guang-Jun; Huang, Tao; Jia, Shu-Yong; Zhang, Yu-Qin; Zhang, Wei-Bo

2013-03-01

To compare the impacts on skin blood flow between moving cupping following the meridian running direction and that against the running direction. JLG-2 meridian cupping drainage instru ment was used for moving cupping on the back along the Bladder Meridian running course in either single direction for 20 times. The cupping device was Bian stone cup, 44 mm in inner diameter, negative pressure from -0.03 to -0.04 MPa. PeriScan PIM II laser Doppler perfusion imager was used to observe the changes in skin blood flow on the running course of the Bladder Meridian with cup moved up and down and in the same region on the contralateral Bladder Meridian. Blood flow was measured before cupping, at the immediate time after cupping and 10 min after cupping separately. Fourteen healthy volunteers received the test. The measuring region was subdivided into a moving cupping area, an upstream area, a downstream area, a contralateral moving cupping area, a contralateral upstream area and a contralateral downstream area. The mean blood flow was calculated in each area. Blood flow was increased significantly in each area and was more apparently increased in the moving cupping area. In comparison of the changing rate of blood flow between cupping following the meridian running direction and that against the running direction, it was only found that the changing rate in the upstream area of moving cupping against the running direction was significantly higher than that following the running direction (P < 0.05). The differences were not statistically significant in comparison among the other areas. Additionally, the changing rates of blood flow in the upstream and downstream area of the Bladder Meridian were increased significantly as compared with the contralateral Bladder Meridian. The local effects are similar between moving cupping following the meridian running direction and that against the running direction. The abscopal effect of moving cupping against the running direction is superior to that following the running direction. It is suggested that the dual-directional moving cupping is applicable for the treatment of local disorders and the abscopal effect is better with moving cupping against the meridian running direction.

Is Moderate Intensity Cycling Sufficient to Induce Cardiorespiratory and Biomechanical Modifications of Subsequent Running?

PubMed

Walsh, Joel A; Dawber, James P; Lepers, Romuald; Brown, Marc; Stapley, Paul J

2017-04-01

Walsh, JA, Dawber, JP, Lepers, R, Brown, M, and Stapley, PJ. Is moderate intensity cycling sufficient to induce cardiorespiratory and biomechanical modifications of subsequent running? J Strength Cond Res 31(4): 1078-1086, 2017-This study sought to determine whether prior moderate intensity cycling is sufficient to influence the cardiorespiratory and biomechanical responses during subsequent running. Cardiorespiratory and biomechanical variables measured after moderate intensity cycling were compared with control running at the same intensity. Eight highly trained, competitive triathletes completed 2 separate exercise tests; (a) a 10-minute control run (no prior cycling) and, (b) a 30-minute transition run (TR) (preceded by 20-minute of variable cadence cycling, i.e., run versus cycle-run). Respiratory, breathing frequency (fb), heart rate (HR), cost of running (Cr), rate constant, stride length, and stride frequency variables were recorded, normalized, and quantified at the mean response time (MRT), third minute, 10th minute (steady state), and overall for the control run (CR) and TR. Cost of running increased (p ≤ 0.05) at all respective times during the TR. The V[Combining Dot Above]E/V[Combining Dot Above]CO2 and respiratory exchange ratio (RER) were significantly (p < 0.01) elevated at the MRT and 10th minute of the TR. Furthermore, overall mean increases were recorded for Cr, V[Combining Dot Above]E, V[Combining Dot Above]E/V[Combining Dot Above]CO2, RER, fb (p < 0.01), and HR (p ≤ 0.05) during the TR. Rate constant values for oxygen uptake were significantly different between CR and TR (0.48 ± 0.04 vs. 0.89 ± 0.15; p < 0.01). Stride length decreased across all recorded points during the TR (p ≤ 0.05) and stride frequency increased at the MRT and 3 minutes (p < 0.01). The findings suggest that at moderate intensity, prior cycling influences the cardiorespiratory response during subsequent running. Furthermore, prior cycling seems to have a sustained effect on the Cr during subsequent running.

Effects of cognitive stimulation with a self-modeling video on time to exhaustion while running at maximal aerobic velocity: a pilot study.

PubMed

Hagin, Vincent; Gonzales, Benoît R; Groslambert, Alain

2015-04-01

This study assessed whether video self-modeling improves running performance and influences the rate of perceived exertion and heart rate response. Twelve men (M age=26.8 yr., SD=6; M body mass index=22.1 kg.m(-2), SD=1) performed a time to exhaustion running test at 100 percent maximal aerobic velocity while focusing on a video self-modeling loop to synchronize their stride. Compared to the control condition, there was a significant increase of time to exhaustion. Perceived exertion was lower also, but there was no significant change in mean heart rate. In conclusion, the video self-modeling used as a pacer apparently increased endurance by decreasing perceived exertion without affecting the heart rate.

Exploring storage and runoff generation processes for urban flooding through a physically based watershed model

NASA Astrophysics Data System (ADS)

Smith, B. K.; Smith, J. A.; Baeck, M. L.; Miller, A. J.

2015-03-01

A physically based model of the 14 km2 Dead Run watershed in Baltimore County, MD was created to test the impacts of detention basin storage and soil storage on the hydrologic response of a small urban watershed during flood events. The Dead Run model was created using the Gridded Surface Subsurface Hydrologic Analysis (GSSHA) algorithms and validated using U.S. Geological Survey stream gaging observations for the Dead Run watershed and 5 subbasins over the largest 21 warm season flood events during 2008-2012. Removal of the model detention basins resulted in a median peak discharge increase of 11% and a detention efficiency of 0.5, which was defined as the percent decrease in peak discharge divided by percent detention controlled area. Detention efficiencies generally decreased with increasing basin size. We tested the efficiency of detention basin networks by focusing on the "drainage network order," akin to the stream order but including storm drains, streams, and culverts. The detention efficiency increased dramatically between first-order detention and second-order detention but was similar for second and third-order detention scenarios. Removal of the soil compacted layer, a common feature in urban soils, resulted in a 7% decrease in flood peak discharges. This decrease was statistically similar to the flood peak decrease caused by existing detention. Current soil storage within the Dead Run watershed decreased flood peak discharges by a median of 60%. Numerical experiment results suggested that detention basin storage and increased soil storage have the potential to substantially decrease flood peak discharges.

40 CFR 86.1772-99 - Road load power, test weight, and inertia weight class determination.

Code of Federal Regulations, 2012 CFR

2012-07-01

... vehicle under all-electric power to complete the running loss test fuel tank temperature profile test sequence without air conditioning and the same vehicle tested over the running loss test fuel tank... fan modes with the system set at 72 deg. F. The running loss test fuel tank temperature profile test...

40 CFR 86.1772-99 - Road load power, test weight, and inertia weight class determination.

Code of Federal Regulations, 2011 CFR

2011-07-01

... vehicle under all-electric power to complete the running loss test fuel tank temperature profile test sequence without air conditioning and the same vehicle tested over the running loss test fuel tank... fan modes with the system set at 72 deg. F. The running loss test fuel tank temperature profile test...

40 CFR 86.1772-99 - Road load power, test weight, and inertia weight class determination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... vehicle under all-electric power to complete the running loss test fuel tank temperature profile test sequence without air conditioning and the same vehicle tested over the running loss test fuel tank... fan modes with the system set at 72 deg. F. The running loss test fuel tank temperature profile test...

Performance of the CMS precision electromagnetic calorimeter at LHC Run II and prospects for High-Luminosity LHC

NASA Astrophysics Data System (ADS)

Zhang, Zhicai

2018-04-01

Many physics analyses using the Compact Muon Solenoid (CMS) detector at the LHC require accurate, high-resolution electron and photon energy measurements. Following the excellent performance achieved during LHC Run I at center-of-mass energies of 7 and 8 TeV, the CMS electromagnetic calorimeter (ECAL) is operating at the LHC with proton-proton collisions at 13 TeV center-of-mass energy. The instantaneous luminosity delivered by the LHC during Run II has achieved unprecedented levels. The average number of concurrent proton-proton collisions per bunch-crossing (pileup) has reached up to 40 interactions in 2016 and may increase further in 2017. These high pileup levels necessitate a retuning of the ECAL readout and trigger thresholds and reconstruction algorithms. In addition, the energy response of the detector must be precisely calibrated and monitored. We present new reconstruction algorithms and calibration strategies that were implemented to maintain the excellent performance of the CMS ECAL throughout Run II. We will show performance results from the 2015-2016 data taking periods and provide an outlook on the expected Run II performance in the years to come. Beyond the LHC, challenging running conditions for CMS are expected after the High-Luminosity upgrade of the LHC (HL-LHC) . We review the design and R&D studies for the CMS ECAL and present first test beam studies. Particular challenges at HL-LHC are the harsh radiation environment, the increasing data rates, and the extreme level of pile-up events, with up to 200 simultaneous proton-proton collisions. We present test beam results of hadron irradiated PbWO crystals up to fluences expected at the HL-LHC . We also report on the R&D for the new readout and trigger electronics, which must be upgraded due to the increased trigger and latency requirements at the HL-LHC.

Single Common Powertrain Lubricant Development

DTIC Science & Technology

2012-01-01

2 2.2 ENGINE DURABILITY TESTING...Page Figure 1 – General Engine Products 6.5L(T) Test Cell Installation ............................................... 9 Figure 2 ... 2 Run 3 Repeatability Run - 1 Repeatability Run - 2 Repeatability Run - 3 3-Run Average Engine Oil Consumption [lb/hr] 0.061 0.082 0.086 0.076

Renewable energy consumption and economic growth in nine OECD countries: bounds test approach and causality analysis.

PubMed

Hung-Pin, Lin

2014-01-01

The purpose of this paper is to investigate the short-run and long-run causality between renewable energy (RE) consumption and economic growth (EG) in nine OECD countries from the period between 1982 and 2011. To examine the linkage, this paper uses the autoregressive distributed lag (ARDL) bounds testing approach of cointegration test and vector error-correction models to test the causal relationship between variables. The co-integration and causal relationships are found in five countries-United States of America (USA), Japan, Germany, Italy, and United Kingdom (UK). The overall results indicate that (1) a short-run unidirectional causality runs from EG to RE in Italy and UK; (2) long-run unidirectional causalities run from RE to EG for Germany, Italy, and UK; (3) a long-run unidirectional causality runs from EG to RE in USA, and Japan; (4) both long-run and strong unidirectional causalities run from RE to EG for Germany and UK; and (5) Finally, both long-run and strong unidirectional causalities run from EG to RE in only USA. Further evidence reveals that policies for renewable energy conservation may have no impact on economic growth in France, Denmark, Portugal, and Spain.

Renewable Energy Consumption and Economic Growth in Nine OECD Countries: Bounds Test Approach and Causality Analysis

PubMed Central

Hung-Pin, Lin

2014-01-01

The purpose of this paper is to investigate the short-run and long-run causality between renewable energy (RE) consumption and economic growth (EG) in nine OECD countries from the period between 1982 and 2011. To examine the linkage, this paper uses the autoregressive distributed lag (ARDL) bounds testing approach of cointegration test and vector error-correction models to test the causal relationship between variables. The co-integration and causal relationships are found in five countries—United States of America (USA), Japan, Germany, Italy, and United Kingdom (UK). The overall results indicate that (1) a short-run unidirectional causality runs from EG to RE in Italy and UK; (2) long-run unidirectional causalities run from RE to EG for Germany, Italy, and UK; (3) a long-run unidirectional causality runs from EG to RE in USA, and Japan; (4) both long-run and strong unidirectional causalities run from RE to EG for Germany and UK; and (5) Finally, both long-run and strong unidirectional causalities run from EG to RE in only USA. Further evidence reveals that policies for renewable energy conservation may have no impact on economic growth in France, Denmark, Portugal, and Spain. PMID:24558343

40 CFR 86.1438 - Test run-EPA.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Test run-EPA. 86.1438 Section 86.1438 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Short Test Procedures § 86.1438 Test run—EPA. (a) This section describes the test run performed by the...

40 CFR 86.1438 - Test run-EPA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Test run-EPA. 86.1438 Section 86.1438 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Short Test Procedures § 86.1438 Test run—EPA. (a) This section describes the test run performed by the...

40 CFR 86.1438 - Test run-EPA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 20 2013-07-01 2013-07-01 false Test run-EPA. 86.1438 Section 86.1438 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Short Test Procedures § 86.1438 Test run—EPA. (a) This section describes the test run performed by the...

40 CFR 86.1437 - Test run-manufacturer.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Test run-manufacturer. 86.1437 Section... Trucks; Certification Short Test Procedures § 86.1437 Test run—manufacturer. (a) This section describes the test run performed by the manufacturer for its data submittal pursuant to obtaining a certificate...

Advanced Coal Liquefaction Research and Development Facility, Wilsonville, Alabama. Run 260 with Black Thunder Mine subbituminous coal: Technical progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report presents the results of Run 260 performed at the Advanced Coal Liquefaction R&D Facility in Wilsonville. The run was started on July 17, 1990 and continued until November 14, 1990, operating in the Close-Coupled Integrated Two-Stage Liquefaction mode processing Black Thunder mine subbituminous coal (Wyodak-Anderson seam from Wyoming Powder River Basin). Both thermal/catalytic and catalytic/thermal tests were performed to determine the methods for reducing solids buildup in a subbituminous coal operation, and to improve product yields. A new, smaller interstage separator was tested to reduce solids buildup by increasing the slurry space velocity in the separator. In ordermore » to obtain improved coal and resid conversions (compared to Run 258) full-volume thermal reactor and 3/4-volume catalytic reactor were used. Shell 324 catalyst, 1/16 in. cylindrical extrudate, at a replacement rate of 3 lb/ton of MF coal was used in the catalytic stage. Iron oxide was used as slurry catalyst at a rate of 2 wt % MF coal throughout the run. (TNPS was the sulfiding agent.)« less

Lower-volume muscle-damaging exercise protects against high-volume muscle-damaging exercise and the detrimental effects on endurance performance.

PubMed

Burt, Dean; Lamb, Kevin; Nicholas, Ceri; Twist, Craig

2015-07-01

This study examined whether lower-volume exercise-induced muscle damage (EIMD) performed 2 weeks before high-volume muscle-damaging exercise protects against its detrimental effect on running performance. Sixteen male participants were randomly assigned to a lower-volume (five sets of ten squats, n = 8) or high-volume (ten sets of ten squats, n = 8) EIMD group and completed baseline measurements for muscle soreness, knee extensor torque, creatine kinase (CK), a 5-min fixed-intensity running bout and a 3-km running time-trial. Measurements were repeated 24 and 48 h after EIMD, and the running time-trial after 48 h. Two weeks later, both groups repeated the baseline measurements, ten sets of ten squats and the same follow-up testing (Bout 2). Data analysis revealed increases in muscle soreness and CK and decreases in knee extensor torque 24-48 h after the initial bouts of EIMD. Increases in oxygen uptake [Formula: see text], minute ventilation [Formula: see text] and rating of perceived exertion were observed during fixed-intensity running 24-48 h after EIMD Bout 1. Likewise, time increased and speed and [Formula: see text] decreased during a 3-km running time-trial 48 h after EIMD. Symptoms of EIMD, responses during fixed-intensity and running time-trial were attenuated in the days after the repeated bout of high-volume EIMD performed 2 weeks after the initial bout. This study demonstrates that the protective effect of lower-volume EIMD on subsequent high-volume EIMD is transferable to endurance running. Furthermore, time-trial performance was found to be preserved after a repeated bout of EIMD.

Total hydrocarbon content (THC) testing in liquid oxygen (LOX) systems

NASA Astrophysics Data System (ADS)

Meneghelli, B. J.; Obregon, R. E.; Ross, H. R.; Hebert, B. J.; Sass, J. P.; Dirschka, G. E.

2015-12-01

The measured Total Hydrocarbon Content (THC) levels in liquid oxygen (LOX) systems at Stennis Space Center (SSC) have shown wide variations. Examples of these variations include the following: 1) differences between vendor-supplied THC values and those obtained using standard SSC analysis procedures; and 2) increasing THC values over time at an active SSC test stand in both storage and run vessels. A detailed analysis of LOX sampling techniques, analytical instrumentation, and sampling procedures will be presented. Additional data obtained on LOX system operations and LOX delivery trailer THC values during the past 12-24 months will also be discussed. Field test results showing THC levels and the distribution of the THC's in the test stand run tank, modified for THC analysis via dip tubes, will be presented.

Total Hydrocarbon Content (THC) Testing in Liquid Oxygen (LOX)

NASA Technical Reports Server (NTRS)

Meneghelli, B. J.; Obregon, R. E.; Ross, H. R.; Hebert, B. J.; Sass, J. P.; Dirschka, G. E.

2016-01-01

The measured Total Hydrocarbon Content (THC) levels in liquid oxygen (LOX) systems at Stennis Space Center (SSC) have shown wide variations. Examples of these variations include the following: 1) differences between vendor-supplied THC values and those obtained using standard SSC analysis procedures; and 2) increasing THC values over time at an active SSC test stand in both storage and run vessels. A detailed analysis of LOX sampling techniques, analytical instrumentation, and sampling procedures will be presented. Additional data obtained on LOX system operations and LOX delivery trailer THC values during the past 12-24 months will also be discussed. Field test results showing THC levels and the distribution of the THC's in the test stand run tank, modified for THC analysis via dip tubes, will be presented.

Effect of intense interval workouts on running economy using three recovery durations.

PubMed

Zavorsky, G S; Montgomery, D L; Pearsall, D J

1998-02-01

The purposes of this study were to determine whether running economy (RE) is adversely affected following intense interval bouts of 10 x 400-m running, and whether there is an interaction effect between RE and recovery duration during the workouts. Twelve highly trained male endurance athletes [maximal oxygen consumption; VO2max = 72.5 (4.3) ml x kg(-1) x min(-1) mean (SD)] performed three interval running workouts of 10 x 400 m with a minimum of 4 days between runs. Recovery duration between the repetitions was randomly assigned at 60, 120 or 180 s. The velocity for each 400-m run was determined from a treadmill VO2max test. The average running velocity was 357.9 (9.0) m x min(-1). Following the workout, the rating of perceived exertion (RPE) increased significantly (P < 0.01) as recovery duration between the 400-m repetitions decreased (14.4, 16.1, and 17.7 at 180s, 120s, and 60 s recovery, respectively). Prior to and following each workout, RE was measured at speeds of 200 and 268 m x min(-1). Changes in RE from pre- to post-workout, as well as heart rate (HR) and respiratory exchange ratio (R) were similar for the three recovery conditions. When averaged across conditions, oxygen consumption (VO2) increased significantly (P < 0.01) from pre- to post-test [from 38.5 to 40.5 ml x kg(-1) x min(-1) at 200 m x min(-1), and from 53.1 to 54.5 ml x kg(-1) x min(-1) at 268 m x min(-1), respectively]. HR increased (from 124 to 138, and from 151 to 157 beats x min(-1) respectively) and R decreased (from 0.90 to 0.78, and from 0.93 to 0.89, respectively) at 200 and 268 m x min(-1), respectively (P < 0.01). This study showed that RE can be perturbed after a high-intensity interval workout and that the changes in VO2, HR and R were independent of the recovery duration between the repetitions.

40 CFR 90.409 - Engine dynamometer test run.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). (3) Record all pre-test data specified in § 90.405(c). (4) Start the test cycle (see § 90.410) within... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Engine dynamometer test run. 90.409... Test Procedures § 90.409 Engine dynamometer test run. (a) Engine and dynamometer start-up. (1) Only...

40 CFR 90.409 - Engine dynamometer test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

...). (3) Record all pre-test data specified in § 90.405(c). (4) Start the test cycle (see § 90.410) within... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Engine dynamometer test run. 90.409... Test Procedures § 90.409 Engine dynamometer test run. (a) Engine and dynamometer start-up. (1) Only...

40 CFR 90.409 - Engine dynamometer test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). (3) Record all pre-test data specified in § 90.405(c). (4) Start the test cycle (see § 90.410) within... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Engine dynamometer test run. 90.409... Test Procedures § 90.409 Engine dynamometer test run. (a) Engine and dynamometer start-up. (1) Only...

40 CFR 90.409 - Engine dynamometer test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (3) Record all pre-test data specified in § 90.405(c). (4) Start the test cycle (see § 90.410) within... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Engine dynamometer test run. 90.409... Test Procedures § 90.409 Engine dynamometer test run. (a) Engine and dynamometer start-up. (1) Only...

40 CFR 90.409 - Engine dynamometer test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (3) Record all pre-test data specified in § 90.405(c). (4) Start the test cycle (see § 90.410) within... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Engine dynamometer test run. 90.409... Test Procedures § 90.409 Engine dynamometer test run. (a) Engine and dynamometer start-up. (1) Only...

Computer-based testing of the modified essay question: the Singapore experience.

PubMed

Lim, Erle Chuen-Hian; Seet, Raymond Chee-Seong; Oh, Vernon M S; Chia, Boon-Lock; Aw, Marion; Quak, Seng-Hock; Ong, Benjamin K C

2007-11-01

The modified essay question (MEQ), featuring an evolving case scenario, tests a candidate's problem-solving and reasoning ability, rather than mere factual recall. Although it is traditionally conducted as a pen-and-paper examination, our university has run the MEQ using computer-based testing (CBT) since 2003. We describe our experience with running the MEQ examination using the IVLE, or integrated virtual learning environment (https://ivle.nus.edu.sg), provide a blueprint for universities intending to conduct computer-based testing of the MEQ, and detail how our MEQ examination has evolved since its inception. An MEQ committee, comprising specialists in key disciplines from the departments of Medicine and Paediatrics, was formed. We utilized the IVLE, developed for our university in 1998, as the online platform on which we ran the MEQ. We calculated the number of man-hours (academic and support staff) required to run the MEQ examination, using either a computer-based or pen-and-paper format. With the support of our university's information technology (IT) specialists, we have successfully run the MEQ examination online, twice a year, since 2003. Initially, we conducted the examination with short-answer questions only, but have since expanded the MEQ examination to include multiple-choice and extended matching questions. A total of 1268 man-hours was spent in preparing for, and running, the MEQ examination using CBT, compared to 236.5 man-hours to run it using a pen-and-paper format. Despite being more labour-intensive, our students and staff prefer CBT to the pen-and-paper format. The MEQ can be conducted using a computer-based testing scenario, which offers several advantages over a pen-and-paper format. We hope to increase the number of questions and incorporate audio and video files, featuring clinical vignettes, to the MEQ examination in the near future.

The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues.

PubMed

Pate, Kathryn M; Sherk, Vanessa D; Carpenter, R Dana; Weaver, Michael; Crapo, Silvia; Gally, Fabienne; Chatham, Lillian S; Goldstrohm, David A; Crapo, James D; Kohrt, Wendy M; Bowler, Russell P; Oberley-Deegan, Rebecca E; Regan, Elizabeth A

2015-03-15

Osteoarthritis (OA) is associated with increased mechanical damage to joint cartilage. We have previously found that extracellular superoxide dismutase (ECSOD) is decreased in OA joint fluid and cartilage, suggesting oxidant damage may play a role in OA. We explored the effect of forced running as a surrogate for mechanical damage in a transgenic mouse with reduced ECSOD tissue binding. Transgenic mice heterozygous (Het) for the human ECSOD R213G polymorphism and 129-SvEv (wild-type, WT) mice were exposed to forced running on a treadmill for 45 min/day, 5 days/wk, over 8 wk. At the end of the running protocol, knee joint tissue was obtained for histology, immunohistochemistry, and protein analysis. Sedentary Het and WT mice were maintained for comparison. Whole tibias were studied for bone morphometry, finite element analysis, and mechanical testing. Forced running improved joint histology in WT mice. However, when ECSOD levels were reduced, this beneficial effect with running was lost. Het ECSOD runner mice had significantly worse histology scores compared with WT runner mice. Runner mice for both strains had increased bone strength in response to the running protocol, while Het mice showed evidence of a less robust bone structure in both runners and untrained mice. Reduced levels of ECSOD in cartilage produced joint damage when joints were stressed by forced running. The bone tissues responded to increased loading with hypertrophy, regardless of mouse strain. We conclude that ECSOD plays an important role in protecting cartilage from damage caused by mechanical loading. Copyright © 2015 the American Physiological Society.

Health Risk Factors Associated with Acute Respiratory Illness Among U.S. Army Recruits Attending Basic Combat Training

DTIC Science & Technology

2012-06-11

Competitive athletes recognize peak performance on the field requires consistent intense practice off the field. Recreational sports enthusiasts to Olympic...challenging as a first time marathon runner. Recreational runners tend to run at comfortable distances and intensities, competitive athletes...level of aerobic fitness, as reflected by poor performance on the initial one-mile run test, may experience increased ARI incidence as 3   a result

40 CFR 86.137-90 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... filters to the weighing chamber for post-test conditioning, if applicable. (22) Disconnect the exhaust... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Dynamometer test run, gaseous and... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-90 Dynamometer test run, gaseous...

40 CFR 86.137-90 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... filters to the weighing chamber for post-test conditioning, if applicable. (22) Disconnect the exhaust... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Dynamometer test run, gaseous and... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-90 Dynamometer test run, gaseous...

40 CFR 86.137-90 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... filters to the weighing chamber for post-test conditioning, if applicable. (22) Disconnect the exhaust... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Dynamometer test run, gaseous and... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-90 Dynamometer test run, gaseous...

40 CFR 86.137-90 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... filters to the weighing chamber for post-test conditioning, if applicable. (22) Disconnect the exhaust... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Dynamometer test run, gaseous and... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-90 Dynamometer test run, gaseous...

40 CFR 86.137-94 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... filters to the weighing chamber for post-test conditioning, if applicable. (22) Disconnect the exhaust... 40 Protection of Environment 19 2014-07-01 2014-07-01 false Dynamometer test run, gaseous and... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-94 Dynamometer test run, gaseous...

40 CFR 92.126 - Test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (5) Read and record all required general and pre-test data (i.e., all required data other than data... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Test run. 92.126 Section 92.126... POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.126 Test run. (a) The following steps...

40 CFR 92.126 - Test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (5) Read and record all required general and pre-test data (i.e., all required data other than data... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Test run. 92.126 Section 92.126... POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.126 Test run. (a) The following steps...

40 CFR 92.126 - Test run.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). (5) Read and record all required general and pre-test data (i.e., all required data other than data... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Test run. 92.126 Section 92.126... POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.126 Test run. (a) The following steps...

40 CFR 92.126 - Test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). (5) Read and record all required general and pre-test data (i.e., all required data other than data... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Test run. 92.126 Section 92.126... POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.126 Test run. (a) The following steps...

40 CFR 92.126 - Test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

...). (5) Read and record all required general and pre-test data (i.e., all required data other than data... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Test run. 92.126 Section 92.126... POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.126 Test run. (a) The following steps...

Effects of size, sex, and voluntary running speeds on costs of locomotion in lines of laboratory mice selectively bred for high wheel-running activity.

PubMed

Rezende, Enrico L; Kelly, Scott A; Gomes, Fernando R; Chappell, Mark A; Garland, Theodore

2006-01-01

Selective breeding for over 35 generations has led to four replicate (S) lines of laboratory house mice (Mus domesticus) that run voluntarily on wheels about 170% more than four random-bred control (C) lines. We tested whether S lines have evolved higher running performance by increasing running economy (i.e., decreasing energy spent per unit of distance) as a correlated response to selection, using a recently developed method that allows for nearly continuous measurements of oxygen consumption (VO2) and running speed in freely behaving animals. We estimated slope (incremental cost of transport [COT]) and intercept for regressions of power (the dependent variable, VO2/min) on speed for 49 males and 47 females, as well as their maximum VO2 and speeds during wheel running, under conditions mimicking those that these lines face during the selection protocol. For comparison, we also measured COT and maximum aerobic capacity (VO2max) during forced exercise on a motorized treadmill. As in previous studies, the increased wheel running of S lines was mainly attributable to increased average speed, with males also showing a tendency for increased time spent running. On a whole-animal basis, combined analysis of males and females indicated that COT during voluntary wheel running was significantly lower in the S lines (one-tailed P=0.015). However, mice from S lines are significantly smaller and attain higher maximum speeds on the wheels; with either body mass or maximum speed (or both) entered as a covariate, the statistical significance of the difference in COT is lost (one-tailed P> or =0.2). Thus, both body size and behavior are key components of the reduction in COT. Several statistically significant sex differences were observed, including lower COT and higher resting metabolic rate in females. In addition, maximum voluntary running speeds were negatively correlated with COT in females but not in males. Moreover, males (but not females) from the S lines exhibited significantly higher treadmill VO2max as compared to those from C lines. The sex-specific responses to selection may in part be consequences of sex differences in body mass and running style. Our results highlight how differences in size and running speed can account for lower COT in S lines and suggest that lower COT may have coadapted in response to selection for higher running distances in these lines.

Downhill Running Excessive Training Inhibits Hypertrophy in Mice Skeletal Muscles with Different Fiber Type Composition.

PubMed

da Rocha, Alisson L; Pereira, Bruno C; Pauli, José R; de Souza, Claudio T; Teixeira, Giovana R; Lira, Fábio S; Cintra, Dennys E; Ropelle, Eduardo R; Júnior, Carlos R B; da Silva, Adelino S R

2016-05-01

The aim of this study was to verify the effects of running overtraining protocols performed in downhill, uphill, and without inclination on the proteins related to hypertrophy signaling pathway in extensor digitorum longus (EDL) and soleus of C57BL/6 mice. We also performed histological and stereological analyses. Rodents were divided into control (CT; sedentary mice), overtrained by downhill running (OTR/down), overtrained by uphill running (OTR/up), and overtrained by running without inclination (OTR). The incremental load, exhaustive, and grip force tests were used as performance evaluation parameters. 36 h after the grip force test, EDL and soleus were removed and immediately used for immunoblotting analysis or stored at -80°C for histological and stereological analyses. For EDL, OTR/down decreased the protein kinase B (Akt) and tuberous sclerosis protein 2 (TSC2) phosphorylation (p), and increased myostatin, receptor-activated Smads (pSMAD2-3), and insulin receptor substrate-1 (pIRS-1; Ser307/636). OTR/down also presented low and high relative proportions of cytoplasm and connective tissue, respectively. OTR/up increased the mammalian target of rapamycin (pmTOR), 70-kDa ribosomal protein S6 kinase 1 (pS6K1) and pSMAD2-3, and decreased pTSC2. OTR decreased pTSC2 and increased pIRS-1 (Ser636). For soleus, OTR/down increased S6 ribosomal protein (pS6RP) and pSMAD2-3, and decreased pIRS-1 (Ser639). OTR/up decreased pS6K1, pS6RP and pIRS-1 (Ser639), and increased pTSC2 (Ser939), and pSMAD2-3. OTR increased pS6RP, 4E-binding protein-1 (p4E-BP1), pTSC2 (Ser939), and pSMAD2-3, and decreased pIRS-1 (Ser639). In summary, OTR/down inhibited the skeletal muscle hypertrophy with concomitant signs of atrophy in EDL. The effects of OTR/up and OTR depended on the analyzed skeletal muscle type. © 2015 Wiley Periodicals, Inc.

Effects of Whole-body Vibration Training on Sprint Running Kinematics and Explosive Strength Performance

PubMed Central

Giorgos, Paradisis; Elias, Zacharogiannis

2007-01-01

The aim of this study was to investigate the effect of 6 wk of whole body vibration (WBV) training on sprint running kinematics and explosive strength performance. Twenty-four volunteers (12 women and 12 men) participated in the study and were randomised (n = 12) into the experimental and control groups. The WBV group performed a 6-wk program (16-30 min·d-1, 3 times a week) on a vibration platform. The amplitude of the vibration platform was 2.5 mm and the acceleration was 2.28 g. The control group did not participate in any training. Tests were performed Pre and post the training period. Sprint running performance was measured during a 60 m sprint where running time, running speed, step length and step rate were calculated. Explosive strength performance was measured during a counter movement jump (CMJ) test, where jump height and total number of jumps performed in a period of 30 s (30CVJT). Performance in 10 m, 20 m, 40 m, 50 m and 60 m improved significantly after 6 wk of WBV training with an overall improvement of 2.7%. The step length and running speed improved by 5.1% and 3.6%, and the step rate decreased by 3.4%. The countermovement jump height increased by 3.3%, and the explosive strength endurance improved overall by 7.8%. The WBV training period of 6 wk produced significant changes in sprint running kinematics and explosive strength performance. Key pointsWBV training.Sprint running kinematics.Explosive strength performance PMID:24149223

Strategies for Maximizing Successful Drug Substance Technology Transfer Using Engineering, Shake-Down, and Wet Test Runs.

PubMed

Abraham, Sushil; Bain, David; Bowers, John; Larivee, Victor; Leira, Francisco; Xie, Jasmina

2015-01-01

The technology transfer of biological products is a complex process requiring control of multiple unit operations and parameters to ensure product quality and process performance. To achieve product commercialization, the technology transfer sending unit must successfully transfer knowledge about both the product and the process to the receiving unit. A key strategy for maximizing successful scale-up and transfer efforts is the effective use of engineering and shake-down runs to confirm operational performance and product quality prior to embarking on good manufacturing practice runs such as process performance qualification runs. We consider key factors to consider in making the decision to perform shake-down or engineering runs. We also present industry benchmarking results of how engineering runs are used in drug substance technology transfers alongside the main themes and best practices that have emerged. Our goal is to provide companies with a framework for ensuring the "right first time" technology transfers with effective deployment of resources within increasingly aggressive timeline constraints. © PDA, Inc. 2015.

An Exploratory Study Investigating the Effects of Barefoot Running on Working Memory.

PubMed

Alloway, Ross G; Alloway, Tracy Packiam; Magyari, Peter M; Floyd, Shelley

2016-04-01

The aim of the present study was to compare the potential cognitive benefits of running barefoot compared to shod. Young adults (N = 72, M age = 24.4 years, SD = 5.5) ran both barefoot and shod on a running track while stepping on targets (poker chips) and when not stepping on targets. The main finding was that participants performed better on a working memory test when running barefoot compared to shod, but only when they had to step on targets. These results supported the idea that additional attention is needed when running barefoot to avoid stepping on objects that could potentially injure the foot. Significant increases in participant's heart rate were also found in the barefoot condition. No significant differences were found in participants' speed across conditions. These findings suggested that working memory may be enhanced after at least 16 minutes of barefoot running if the individual has to focus attention on the ground. © The Author(s) 2016.

Voluntary wheel running increases satellite cell abundance and improves recovery from disuse in gastrocnemius muscles from mice.

PubMed

Brooks, Matthew J; Hajira, Ameena; Mohamed, Junaith S; Alway, Stephen E

2018-06-01

Reloading of atrophied muscles after hindlimb suspension unloading (HSU) can induce injury and prolong recovery. Low-impact exercise, such as voluntary wheel running, has been identified as a nondamaging rehabilitation therapy in rodents, but its effects on muscle function, morphology, and satellite cell activity after HSU are unclear. This study tested the hypothesis that low-impact wheel running would increase satellite cell proliferation and improve recovery of muscle structure and function after HSU in mice. Young adult male and female C57BL/6 mice ( n = 6/group) were randomly placed into five groups. These included HSU without recovery (HSU), normal ambulatory recovery for 14 days after HSU (HSU+NoWR), and voluntary wheel running recovery for 14 days after HSU (HSU+WR). Two control groups were used: nonsuspended mouse cage controls (Control) and voluntary wheel running controls (ControlWR). Satellite cell activation was evaluated by providing mice 5-bromo-2'-deoxyuridine (BrdU) in their drinking water. As expected, HSU significantly reduced in vivo maximal force, decreased in vivo fatigability, and decreased type I and IIa myosin heavy chain (MHC) abundance in plantarflexor muscles. HSU+WR mice significantly improved plantarflexor fatigue resistance, increased type I and IIa MHC abundance, increased fiber cross-sectional area, and increased the percentage of type I and IIA muscle fibers in the gastrocnemius muscle. HSU+WR mice also had a significantly greater percentage of BrdU-positive and Pax 7-positive nuclei inside muscle fibers and a greater MyoD-to-Pax 7 protein ratio compared with HSU+NoWR mice. The mechanotransduction protein Yes-associated protein (YAP) was elevated with reloading after HSU, but HSU+WR mice had lower levels of the inactive phosphorylated YAP serine127 , which may have contributed to increased satellite cell activation with reloading after HSU. These results indicate that voluntary wheel running increased YAP signaling and satellite cell activity after HSU and this was associated with improved recovery. NEW & NOTEWORTHY Although satellite cell involvement in muscle remodeling has been challenged, the data in this study suggest that voluntary wheel running increased satellite cell activity and suppressed Yes-associated protein (YAP) protein relative to no wheel running and this was associated with improved muscle recovery of force, fatigue resistance, expression of type I myosin heavy chain, and greater fiber cross-sectional area after disuse.

Effects of Marathon Running on Aerobic Fitness and Performance in Recreational Runners One Week after a Race.

PubMed

Takayama, Fuminori; Aoyagi, Atsushi; Shimazu, Wataru; Nabekura, Yoshiharu

2017-01-01

It is not clear whether or not recreational runners can recover aerobic fitness and performance within one week after marathon running. This study aimed to investigate the effects of running a marathon race on aerobic fitness and performance one week later. Eleven recreational runners (six men, five women) completed the race in 3 h 36 min 20 s ± 41 min 34 s (mean ± standard deviation). Before and 7 days after the race, they performed a treadmill running test. Perceived muscle soreness was assessed before the race and for the following 7 days. The magnitude of changes in the treadmill running test was considered possibly trivial for maximal oxygen uptake ([Formula: see text]O 2 max) (mean difference -1.2 ml/kg/min; ±90% confidence limits 2 ml/kg/min), unclear for %[Formula: see text]O 2 max at anaerobic threshold (AT) (-0.5; ±4.1%) and RE (0.2; ±3.5 ml/kg/km), and likely trivial for both velocity at AT and peak (-0.2; ±0.49 km/h and -0.3; ±0.28 km/h). Perceived muscle soreness increased until 3 days after the race, but there were no clear differences between the values before the race and 4-7 days after it. These results show that physiological capacity associated with marathon running performance is recovered within 7 days after a marathon run.

Effects of Marathon Running on Aerobic Fitness and Performance in Recreational Runners One Week after a Race

PubMed Central

Aoyagi, Atsushi; Shimazu, Wataru

2017-01-01

It is not clear whether or not recreational runners can recover aerobic fitness and performance within one week after marathon running. This study aimed to investigate the effects of running a marathon race on aerobic fitness and performance one week later. Eleven recreational runners (six men, five women) completed the race in 3 h 36 min 20 s ± 41 min 34 s (mean ± standard deviation). Before and 7 days after the race, they performed a treadmill running test. Perceived muscle soreness was assessed before the race and for the following 7 days. The magnitude of changes in the treadmill running test was considered possibly trivial for maximal oxygen uptake (V˙O2max) (mean difference −1.2 ml/kg/min; ±90% confidence limits 2 ml/kg/min), unclear for %V˙O2max at anaerobic threshold (AT) (−0.5; ±4.1%) and RE (0.2; ±3.5 ml/kg/km), and likely trivial for both velocity at AT and peak (−0.2; ±0.49 km/h and −0.3; ±0.28 km/h). Perceived muscle soreness increased until 3 days after the race, but there were no clear differences between the values before the race and 4–7 days after it. These results show that physiological capacity associated with marathon running performance is recovered within 7 days after a marathon run. PMID:29138757

Impact of water quality on chlorine demand of corroding copper.

PubMed

Lytle, Darren A; Liggett, Jennifer

2016-04-01

Copper is widely used in drinking water premise plumbing system materials. In buildings such as hospitals, large and complicated plumbing networks make it difficult to maintain good water quality. Sustaining safe disinfectant residuals throughout a building to protect against waterborne pathogens such as Legionella is particularly challenging since copper and other reactive distribution system materials can exert considerable demands. The objective of this work was to evaluate the impact of pH and orthophosphate on the consumption of free chlorine associated with corroding copper pipes over time. A copper test-loop pilot system was used to control test conditions and systematically meet the study objectives. Chlorine consumption trends attributed to abiotic reactions with copper over time were different for each pH condition tested, and the total amount of chlorine consumed over the test runs increased with increasing pH. Orthophosphate eliminated chlorine consumption trends with elapsed time (i.e., chlorine demand was consistent across entire test runs). Orthophosphate also greatly reduced the total amount of chlorine consumed over the test runs. Interestingly, the total amount of chlorine consumed and the consumption rate were not pH dependent when orthophosphate was present. The findings reflect the complex and competing reactions at the copper pipe wall including corrosion, oxidation of Cu(I) minerals and ions, and possible oxidation of Cu(II) minerals, and the change in chlorine species all as a function of pH. The work has practical applications for maintaining chlorine residuals in premise plumbing drinking water systems including large buildings such as hospitals. Published by Elsevier Ltd.

Housing conditions modulate escitalopram effects on antidepressive-like behaviour and brain neurochemistry.

PubMed

Bjørnebekk, Astrid; Mathé, Aleksander A; Gruber, Susanne H M; Brené, Stefan

2008-12-01

Despite limited understanding of the pathophysiology of depression and the underlying mechanisms mediating antidepressant effects, there are several efficient treatments. The anhedonia symptoms of depression are characterized by decreased motivation and drive and imply possible malfunctioning of the mesolimbic dopamine system, whereas cognitive deficits might reflect decreased plasticity in hippocampus. In female Flinders Sensitive Line (FSL) rats, a model of depression, we compared the effects of three long-term antidepressant treatments: voluntary running, escitalopram and the combination of both on antidepressant-like behaviour in the Porsolt swim test (PST), and on regulation of mRNA for dopamine and neuropeptides in striatal dopamine pathways and brain-derived neurotrophic factor (BDNF) in hippocampus. Escitalopram diet attenuated running behaviour in FSL rats but not in non-depressed controls rats. In the PST the running group had increased climbing activity (noradrenergic/dopaminergic response), whereas the combination of escitalopram and running-wheel access increased swimming (serotonergic response). Running elevated mRNA for dynorphin in caudate putamen and BDNF in hippocampus. The combined treatment down-regulated D1 receptor and enkephalin mRNA in accumbens. Escitalopram alone did not affect behaviour or mRNA levels. We demonstrate a novel behavioural effect of escitalopram, i.e. attenuation of running in 'depressed' rats. The antidepressant-like effect of escitalopram was dependent on the presence of a running wheel, but not actual running indicating that the environment influenced the antidepressant effect of escitalopram. Different patterns of mRNA changes in hippocampus and brain reward pathways and responses in the PST by running and escitalopram suggest that antidepressant-like responses by running and escitalopram are achieved by different mechanisms.

In-shoe plantar pressure distribution and lower extremity muscle activity patterns of backward compared to forward running on a treadmill.

PubMed

Sterzing, Thorsten; Frommhold, Clivia; Rosenbaum, Dieter

2016-05-01

Backward locomotion in humans occurs during leisure, rehabilitation, and competitive sports. Little is known about its general biomechanical characteristics and how it affects lower extremity loading as well as muscle coordination. Thus, the purpose of this research was to analyze in-shoe plantar pressure patterns and lower extremity muscle activity patterns for backward compared to forward running. On a treadmill, nineteen runners performed forward running at their individually preferred speed, followed by backward running at 70% of their self-selected forward speed. In-shoe plantar pressures of nine foot regions and muscular activity of nine lower extremity muscles were recorded simultaneously over a one-minute interval. Backward and forward running variables were averaged over the accumulated steps and compared with Wilcoxon-signed rank tests (p<.05). For backward compared to forward running, in-shoe plantar pressure distribution showed a load increase under metatarsal heads I and II, as well as under the medial midfoot. This was indicated by higher maximum forces and peak pressures, and by longer contact times. Muscle activity showed significantly higher mean amplitudes during backward running in the semitendinosus, rectus femoris, vastus lateralis, and gluteus medius during stance, and in the rectus femoris during swing phase, while significantly lower mean amplitudes were observed in the tibialis anterior during swing phase. Observations indicate plantar foot loading and muscle activity characteristics that are specific for the running direction. Thus, backward running may be used on purpose for certain rehabilitation tasks, aiming to strengthen respective lower extremity muscles. Furthermore, the findings are relevant for sport specific backward locomotion training. Finally, results provide an initial baseline for innovative athletic footwear development aiming to increase comfort and performance during backward running. Copyright © 2016 Elsevier B.V. All rights reserved.

78 FR 67218 - Agency Information Collection Activities: Company-Run Annual Stress Test Reporting Template and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... Activities: Company-Run Annual Stress Test Reporting Template and Documentation for Covered Institutions With... titled, ``Company-Run Annual Stress Test Reporting Template and Documentation for Covered Institutions... under News and Issuances ( http://www.occ.treas.gov/tools-forms/forms/bank-operations/stress-test...

40 CFR 86.1234-96 - Running loss test.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 20 2013-07-01 2013-07-01 false Running loss test. 86.1234-96 Section... Emission Test Procedures for New Gasoline-Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1234-96 Running loss test. (a) Overview. Gasoline- and methanol...

40 CFR 86.1234-96 - Running loss test.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Running loss test. 86.1234-96 Section... Emission Test Procedures for New Gasoline-Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1234-96 Running loss test. (a) Overview. Gasoline- and methanol...

40 CFR 86.1234-96 - Running loss test.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Running loss test. 86.1234-96 Section... Emission Test Procedures for New Gasoline-Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1234-96 Running loss test. (a) Overview. Gasoline- and methanol...

40 CFR 86.1234-96 - Running loss test.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Running loss test. 86.1234-96 Section... Emission Test Procedures for New Gasoline-Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1234-96 Running loss test. (a) Overview. Gasoline- and methanol...

Running quietly reduces ground reaction force and vertical loading rate and alters foot strike technique.

PubMed

Phan, Xuan; Grisbrook, Tiffany L; Wernli, Kevin; Stearne, Sarah M; Davey, Paul; Ng, Leo

2017-08-01

This study aimed to determine if a quantifiable relationship exists between the peak sound amplitude and peak vertical ground reaction force (vGRF) and vertical loading rate during running. It also investigated whether differences in peak sound amplitude, contact time, lower limb kinematics, kinetics and foot strike technique existed when participants were verbally instructed to run quietly compared to their normal running. A total of 26 males completed running trials for two sound conditions: normal running and quiet running. Simple linear regressions revealed no significant relationships between impact sound and peak vGRF in the normal and quiet conditions and vertical loading rate in the normal condition. t-Tests revealed significant within-subject decreases in peak sound, peak vGRF and vertical loading rate during the quiet compared to the normal running condition. During the normal running condition, 15.4% of participants utilised a non-rearfoot strike technique compared to 76.9% in the quiet condition, which was corroborated by an increased ankle plantarflexion angle at initial contact. This study demonstrated that quieter impact sound is not directly associated with a lower peak vGRF or vertical loading rate. However, given the instructions to run quietly, participants effectively reduced peak impact sound, peak vGRF and vertical loading rate.

40 CFR 86.884-12 - Test run.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 19 2014-07-01 2014-07-01 false Test run. 86.884-12 Section 86.884-12... Engines; Smoke Exhaust Test Procedure § 86.884-12 Test run. (a) The temperature of the air supplied to the... taken for each test: (1) Start cooling system; (2) Warm up the engine by the procedure described in 40...

40 CFR 86.884-12 - Test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Test run. 86.884-12 Section 86.884-12... Heavy-Duty Engines; Smoke Exhaust Test Procedure § 86.884-12 Test run. (a) The temperature of the air... steps shall be taken for each test: (1) Start cooling system; (2) Warm up the engine by the procedure...

Acute and overuse injuries correlated to hours of training in master running athletes.

PubMed

Knobloch, Karsten; Yoon, Uzung; Vogt, Peter M

2008-07-01

The goal of the study was to determine the rate of running-associated tendinopathy in light of the amount of time training and other risk factors. 291 elite runners (average age 42 +/- 9 years) who ran an average of 65.2 +/- 28.3 km/week were included with an overall distance of 9,980,852 km (34,416 km/athlete). Descriptive statistics with Chi2-Test, Fisher-Exact-Test and Mann-Whitney-Test were used to calculate relative risks (RR). The overall injury rate was 0.08/1000 km (2.93/athlete). Overuse injuries (0.07/1000 km) were more frequent than acute injuries (0.01/1000 km). Achilles tendinopathy was the predominant injury (0.02/1000 km) followed by anterior knee pain (0.01/1000 km), and shin splints (0.01/1000 km). Achilles tendon rupture was rarely encountered (0.001/1000 km). At some time, 56.6% of the athletes had an Achilles tendon overuse injury, 46.4% anterior knee pain, 35.7% shin splints, and 12.7% had plantar fasciitis. Mid-portion Achilles tendinopathy was more common (0.01/1000 km) than insertional (0.005/1000 km). An asphalt running surface decreased mid-portion tendinopathy risk (RR 0.47, p = 0.02). In contrast, sand increased the relative risk for mid-portion Achilles tendinopathy tenfold (RR 10, CI 1.12 to 92.8, p = 0.01). Runners with more than 10 years experience had an increased risk (RR 1.6, p = 0.04) for Achilles tendinopathy. Achilles tendinopathy is the most common running-associated tendinopathy followed by runner's knee and shin splints.

Does respiratory muscle training increase physical performance?

PubMed

Sperlich, Billy; Fricke, Hannes; de Marées, Markus; Linville, John W; Mester, Joachim

2009-09-01

Special force units and military personnel undergo demanding physical exercise and might benefit from high-intensity respiratory muscle training (RMT) by increasing their endurance performance. This study examined the effects of a 6-week high-intensity RMT on running performance and oxygen uptake (VO2max) in a group of German Special Force Squad members. 17 participants were randomly assigned to a training or control group. Baseline and post-testing included a ramp test, as well as an incremental test on a treadmill, performed to physical exhaustion. VO2, respiratory exchange ratio, and heart rate were measured breath by breath. Furthermore, maximum running speed (V(max)), 4 mmol x 1(-1) lactate threshold (V4) and perception of respiratory effort were determined. During pulmonary testing, sustained maximum inspiratory and expiratory pressure (PI(max) and PE(max)) were obtained. RMT was performed daily at approximately 90% PI(max) for 6 weeks with 2 x 30 breath cycles using an Ultrabreathe lung trainer. No statistical differences were detected between the groups for any parameter after RMT. High-intensity RMT did not show any benefits on VO2max and endurance performance and are unlikely to be of benefit to military or paramilitary training programs for an increase in endurance performance.

Effect of increasing maximal aerobic exercise on serum muscles enzymes in professional field hockey players.

PubMed

Hazar, Muhsin; Otag, Aynur; Otag, Ilhan; Sezen, Mehmet; Sever, Ozan

2014-11-04

Exercise results in oxidative enzyme increase and micro-injuries in skeletal muscles. The aim of this study was to investigate the effect of maximal aerobic exercise on serum muscle enzymes in professional field hockey players. This study aims to determine the effect of increasing maximal aerobic exercise on creatine kinase (CK), creatine kinase-MB (CK-MB), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) serum levels. 31 young professional field hockey players (13 female and 18 male players) volunteered for this study. All participants underwent the shuttle run test. Blood samples were taken from each participant before the shuttle run test. Post test blood samples were taken immediately after exercise and one hour after respectively. Pre and post test CK, CK-MB, AST and ALT values were measured by means of auto analyzer using original kits. The acute post test measure of the CK level increased in male (p=0.002) and female (p=0.00) sportsmen. CK-MB values obtained one hour after the exercise was lower than those before the exercise in males (p=0.02). In females (p=0.017) and males (p=0.05) AST activity significantly increased immediately after exercise and decreased to resting activity 1 h recovery. ALT significantly increased immediately after exercise in female (p=0.03) and male (p=0.00) athletes and after 1 h recovery ALT activities decreased below resting values. The timing and severity of exercise used in our study increased CK values, decreased CK-MB values and AST, ALT values increased in female and male field hockey players.

Swimming and cycling overloaded training in triathlon has no effect on running kinematics and economy.

PubMed

Palazzetti, S; Margaritis, I; Guezennec, C Y

2005-04-01

The aim of the study was to verify whether an overloaded training (OT) in triathlon deteriorates running kinematics (RK) and running economy (RE). Thirteen well-trained male long-distance triathletes (age: 28.1 +/- 4.3 yrs; V.O (2max): 65.0 +/- 3.1 ml O (2) . min (-1) . kg (-1)) were divided into two groups: completed an individualized OT program (OG; n = 7) or maintained a normal level of training (NT) (CG; n = 6) for a duration of 3 weeks. Every week, each triathlete completed a standardized questionnaire to quantify the influence of training loads on mood state. To reach OT, total training load (h . 3 wk (-1)) was increased by 24 %; swimming and cycling total volumes were increased by 46 and 57 %, respectively, but the distance run was not modified in order to limit the risk of injuries. RK and RE were determined on treadmill test at 12 km . h (-1) before and after the 3 weeks. The 3-week swimming and cycling OT in triathlon was sufficiently stressful to alter mood state but not to deteriorate the running kinematics and economy parameters in our previously well-trained male long-distance triathletes.

Behavioral Traits are Affected by Selective Breeding for Increased Wheel-Running Behavior in Mice

PubMed Central

Jónás, I.; Schubert, K. A.; Reijne, A. C.; Scholte, J.; Garland, T.; Gerkema, M. P.; Scheurink, A. J. W.; Nyakas, C.

2010-01-01

Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and “information gathering” in the open-field test, either with increased upright positions or horizontal locomotion toward the middle ring. Furthermore, one of the selection lines had an increased risk-taking behavior relative to the control line in approaching a novel object placed in the center of the open field. However, anxiety behavior was increased in selection lines during the plus-maze test. Maze learning was not statistically different among lines, but routine behavior was increased in both selection lines when the maze exit after 2 days of testing was displaced. Specifically, in the displaced maze, selected mice traveled more frequently to the old, habituated exit, bypassing the new exit attached to their home cage. Although the generality of the results would need to be confirmed in future studies including all eight lines in the selection experiment, the increased routine and exploratory behavior (at least in the lines used in the present study) may be adaptive to sustain high activity levels. PMID:20369280

Optimal stride frequencies in running at different speeds.

PubMed

van Oeveren, Ben T; de Ruiter, Cornelis J; Beek, Peter J; van Dieën, Jaap H

2017-01-01

During running at a constant speed, the optimal stride frequency (SF) can be derived from the u-shaped relationship between SF and heart rate (HR). Changing SF towards the optimum of this relationship is beneficial for energy expenditure and may positively change biomechanics of running. In the current study, the effects of speed on the optimal SF and the nature of the u-shaped relation were empirically tested using Generalized Estimating Equations. To this end, HR was recorded from twelve healthy (4 males, 8 females) inexperienced runners, who completed runs at three speeds. The three speeds were 90%, 100% and 110% of self-selected speed. A self-selected SF (SFself) was determined for each of the speeds prior to the speed series. The speed series started with a free-chosen SF condition, followed by five imposed SF conditions (SFself, 70, 80, 90, 100 strides·min-1) assigned in random order. The conditions lasted 3 minutes with 2.5 minutes of walking in between. SFself increased significantly (p<0.05) with speed with averages of 77, 79, 80 strides·min-1 at 2.4, 2.6, 2.9 m·s-1, respectively). As expected, the relation between SF and HR could be described by a parabolic curve for all speeds. Speed did not significantly affect the curvature, nor did it affect optimal SF. We conclude that over the speed range tested, inexperienced runners may not need to adapt their SF to running speed. However, since SFself were lower than the SFopt of 83 strides·min-1, the runners could reduce HR by increasing their SFself.

Effect of Mandatory Unit and Individual Physical Training on Fitness in Military Men and Women.

PubMed

Anderson, Morgan K; Grier, Tyson; Canham-Chervak, Michelle; Bushman, Timothy T; Nindl, Bradley C; Jones, Bruce H

2017-09-01

The purpose of this study was to look at the effect of additional individual physical training (PT) in addition to mandatory unit PT as well as other risk factors on physical fitness. A cross-sectional design. This study was conducted on a US military installation. Participants were 6290 male and 558 female active duty US Army soldiers in 3 light infantry brigades. Participants completed self-administered questionnaires asking about individual characteristics, PT, and physical fitness. Cut points were established for soldiers scoring within the top 33% for each of the 3 Army Physical Fitness Test events (2-mile run, sit-ups, and push-ups) and top 50% in each of the tests combined for overall performance. Odds ratios and 95% confidence intervals from multivariate analyses were calculated. Variables impacting physical fitness performance of men and women included increased body mass index, leading unit PT sessions, and individual distance running mileage. Other variables impacting physical performance for men included increased age, smoking, and individual resistance training. Soldiers performing additional individual PT demonstrated a positive influence on fitness compared to unit PT participation alone. Increased age and being overweight/obese negatively influenced physical fitness. To enhance fitness performance through unit PT, running by ability groups and resistance training should be encouraged by leadership.

The Effect of Journal Roughness and Foil Coatings on the Performance of Heavily Loaded Foil Air Bearings

NASA Technical Reports Server (NTRS)

Radil, Kevin C.; DellaCorte, Christopher

2001-01-01

Foil air bearing load capacity tests were conducted to investigate if a solid lubricant coating applied to the surface of the bearing's top foil can function as a break-in coating. Two foil coating materials, a conventional soft polymer film (polyimide) and a hard ceramic (alumina), were independently evaluated against as-ground and worn (run-in) journals coated with NASA PS304, a high-temperature solid lubricant composite coating. The foil coatings were evaluated at journal rotational speeds of 30,000 rpm and at 25 C. Tests were also performed on a foil bearing with a bare (uncoated) nickel-based superalloy top foil to establish a baseline for comparison. The test results indicate that the presence of a top foil solid lubricant coating is effective at increasing the load capacity performance of the foil bearing. Compared to the uncoated baseline, the addition of the soft polymer coating on the top foil increased the bearing load coefficient by 120% when operating against an as-ground journal surface and 85 percent against a run-in journal surface. The alumina coating increased the load coefficient by 40% against the as-ground journal but did not have any affect when the bearing was operated with the run-in journal. The results suggest that the addition of solid lubricant films provide added lubrication when the air film is marginal indicating that as the load capacity is approached foil air bearings transition from hydrodynamic to mixed and boundary lubrication.

An alternative approach to the Army Physical Fitness Test two-mile run using critical velocity and isoperformance curves.

PubMed

Fukuda, David H; Smith, Abbie E; Kendall, Kristina L; Cramer, Joel T; Stout, Jeffrey R

2012-02-01

The purpose of this study was to evaluate the use of critical velocity (CV) and isoperformance curves as an alternative to the Army Physical Fitness Test (APFT) two-mile running test. Seventy-eight men and women (mean +/- SE; age: 22.1 +/- 0.34 years; VO2(MAX): 46.1 +/- 0.82 mL/kg/min) volunteered to participate in this study. A VO2(MAX) test and four treadmill running bouts to exhaustion at varying intensities were completed. The relationship between total distance and time-to-exhaustion was tracked for each exhaustive run to determine CV and anaerobic running capacity. A VO2(MAX) prediction equation (Coefficient of determination: 0.805; Standard error of the estimate: 3.2377 mL/kg/min) was developed using these variables. Isoperformance curves were constructed for men and women to correspond with two-mile run times from APFT standards. Individual CV and anaerobic running capacity values were plotted and compared to isoperformance curves for APFT 2-mile run scores. Fifty-four individuals were determined to receive passing scores from this assessment. Physiological profiles identified from this procedure can be used to assess specific aerobic or anaerobic training needs. With the use of time-to-exhaustion as opposed to a time-trial format used in the two-mile run test, pacing strategies may be limited. The combination of variables from the CV test and isoperformance curves provides an alternative to standardized time-trial testing.

We Run This City: Impact of a Community-School Fitness Program on Obesity, Health, and Fitness.

PubMed

Borawski, Elaine A; Jones, Sarah Drewes; Yoder, Laura Danosky; Taylor, Tara; Clint, Barbara A; Goodwin, Meredith A; Trapl, Erika S

2018-05-03

The We Run This City (WRTC) Youth Marathon Program is a community-supported, school-based fitness program designed to increase physical activity in a large, urban school district by engaging middle school youth to train 12 to 14 weeks to run or walk 1.2 miles, 6.2 miles, or 13.1 miles of the Rite Aid Cleveland Marathon. The objective of our study was to evaluate the effect of the intervention on adolescent health. We assessed changes in obesity, health, and fitness, measured before training and postintervention, among 1,419 sixth- to eighth-grade students participating in WRTC for the first time, with particular interest in the program's effect on overweight (85th-94th body mass index percentile) or obese (≥95th percentile) students. We collected data from 2009 through 2012, and analyzed it in 2016 and 2017. Outcomes of interest were body mass index (BMI), waist-to-hip ratio (WHR), elevated blood pressure, and fitness levels evaluated by using the Progressive Aerobic Cardiovascular Endurance Run (PACER) test and the sit-to-stand test. We saw significant improvements overall in fitness and blood pressure. Controlling for demographics, program event, and training dosage, BMI percentile increased among normal weight participants and decreased among overweight and obese participants (P < .001). WHR increased among obese participants, whereas reductions in blood pressure among those with elevated blood pressure were associated with higher amounts of training and lower baseline BMI. Even small amounts of regular physical activity can affect the health and fitness of urban youths. School-community partnerships offer a promising approach to increasing physical activity by supporting schools and making a school-based activity inclusive, fun, and connected to the broader fitness community.

Habituation contributes to within-session changes in free wheel running.

PubMed Central

Aoyama, K; McSweeney, F K

2001-01-01

Three experiments tested the hypothesis that habituation contributes to the regulation of wheel running. Rats ran in a wheel for 30-min sessions. Experiment 1 demonstrated spontaneous recovery. Rats ran more and the within-session decreases in running were smaller after 2 days of wheel deprivation than after 1 day. Experiment 2 demonstrated dishabituation. Running rate increased immediately after the termination of a brief extra event (application of the brake or flashing of the houselight). Experiment 3 demonstrated stimulus specificity. Rats completed the second half of the session in either the same wheel as the first half, or a different wheel. Second-half running was faster in the latter case. Within-session patterns of running were well described by equations that describe data from the habituation, motivation, and operant literatures. These results suggest that habituation contributes to the regulation of running. In fact, habituation provides a better explanation for the termination of wheel running than fatigue, the variable to which this termination is usually attributed. Overall, the present findings are consistent with the proposition that habituation and sensitization contribute to the regulation of several forms of motivated behavior. PMID:11768712

77 FR 62378 - Supervisory and Company-Run Stress Test Requirements for Covered Companies

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

... to Both Supervisory and Company-Run Stress Tests The Board designed the final rule in a manner to... to conduct supervisory stress test; and project a company's losses, pre-provision net revenue...-Run Stress Test Requirements; Final Rules #0;#0;Federal Register / Vol. 77 , No. 198 / Friday, October...

40 CFR 86.137-96 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Dynamometer test run, gaseous and particulate emissions. 86.137-96 Section 86.137-96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-96 Dynamometer test run, gaseous...

40 CFR 86.137-96 - Dynamometer test run, gaseous and particulate emissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Dynamometer test run, gaseous and particulate emissions. 86.137-96 Section 86.137-96 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... New Otto-Cycle Complete Heavy-Duty Vehicles; Test Procedures § 86.137-96 Dynamometer test run, gaseous...

Effects of step rate manipulation on joint mechanics during running.

PubMed

Heiderscheit, Bryan C; Chumanov, Elizabeth S; Michalski, Max P; Wille, Christa M; Ryan, Michael B

2011-02-01

the objective of this study was to characterize the biomechanical effects of step rate modification during running on the hip, knee, and ankle joints so as to evaluate a potential strategy to reduce lower extremity loading and risk for injury. three-dimensional kinematics and kinetics were recorded from 45 healthy recreational runners during treadmill running at constant speed under various step rate conditions (preferred, ± 5%, and ± 10%). We tested our primary hypothesis that a reduction in energy absorption by the lower extremity joints during the loading response would occur, primarily at the knee, when step rate was increased. less mechanical energy was absorbed at the knee (P < 0.01) during the +5% and +10% step rate conditions, whereas the hip (P < 0.01) absorbed less energy during the +10% condition only. All joints displayed substantially (P < 0.01) more energy absorption when preferred step rate was reduced by 10%. Step length (P < 0.01), center of mass vertical excursion (P < 0.01), braking impulse (P < 0.01), and peak knee flexion angle (P < 0.01) were observed to decrease with increasing step rate. When step rate was increased 10% above preferred, peak hip adduction angle (P < 0.01) and peak hip adduction (P < 0.01) and internal rotation (P < 0.01) moments were found to decrease. we conclude that subtle increases in step rate can substantially reduce the loading to the hip and knee joints during running and may prove beneficial in the prevention and treatment of common running-related injuries.

A training programme to improve hip strength in persons with lower limb amputation.

PubMed

Nolan, Lee

2012-03-01

To investigate the effect of a 10-week training programme on persons with a lower limb amputation and to determine if this training is sufficient to enable running. Seven transtibial, 8 transfemoral and 1 bilateral amputee (all resulting from trauma, tumour or congenital) were randomly assigned to a training (n  =8) or control group (n = 8). Isokinetic hip flexor and extensor strength at 60 and 120º/s and oxygen consumption while walking at 1.0 m/s were tested pre- and post- a 10-week period. The training group followed a twice weekly hip strengthening programme, while the control group continued with their usual activities. Running ability was determined pre-testing, and attempted after post-testing for the training group only. The training group increased hip strength and decreased oxygen consumption. Six amputees who were previously unable to run were able to after training. The control group decreased intact limb hip extensor strength. The training programme is sufficient to improve hip strength and enable running in persons with a lower limb amputation. As hip strength was reduced in those not following the training programme, it is recommended that strength training be undertaken regularly in order to avoid losing limb strength following amputation.

Effects of Heavy Strength Training on Running Performance and Determinants of Running Performance in Female Endurance Athletes

PubMed Central

Vikmoen, Olav; Raastad, Truls; Seynnes, Olivier; Bergstrøm, Kristoffer; Ellefsen, Stian; Rønnestad, Bent R.

2016-01-01

Purpose The purpose of the current study was to investigate the effects of adding strength training to normal endurance training on running performance and running economy in well-trained female athletes. We hypothesized that the added strength training would improve performance and running economy through altered stiffness of the muscle-tendon complex of leg extensors. Methods Nineteen female endurance athletes [maximal oxygen consumption (VO2max): 53±3 ml∙kg-1∙min-1, 5.8 h weekly endurance training] were randomly assigned to either normal endurance training (E, n = 8) or normal endurance training combined with strength training (E+S, n = 11). The strength training consisted of four leg exercises [3 x 4–10 repetition maximum (RM)], twice a week for 11 weeks. Muscle strength, 40 min all-out running distance, running performance determinants and patellar tendon stiffness were measured before and after the intervention. Results E+S increased 1RM in leg exercises (40 ± 15%) and maximal jumping height in counter movement jump (6 ± 6%) and squat jump (9 ± 7%, p < 0.05). This was accompanied by increased muscle fiber cross sectional area of both fiber type I (13 ± 7%) and fiber type II (31 ± 20%) in m. vastus lateralis (p < 0.05), with no change in capillary density in m. vastus lateralis or the stiffness of the patellar tendon. Neither E+S nor E changed running economy, fractional utilization of VO2max or VO2max. There were also no change in running distance during a 40 min all-out running test in neither of the groups. Conclusion Adding heavy strength training to endurance training did not affect 40 min all-out running performance or running economy compared to endurance training only. PMID:26953893

Effects of form-focused training on running biomechanics: A pilot randomized trial in untrained individuals

PubMed Central

Kumar, Deepak; McDermott, Kelly; Feng, Haojun; Goldman, Veronica; Luke, Anthony; Souza, Richard B; Hecht, Frederick M

2015-01-01

Objective To investigate the changes in running biomechanics after training in Form-Focused running using ChiRunning vs. Not-Form focused training and Self-Directed training in untrained individuals. Design Pilot study - Randomized controlled trial. Setting Research Institution with Tertiary Care Medical Center. Participants Seventeen subjects (9 males, 8 females) with pre-hypertension. Methods Twenty-two participants were randomized to three study arms but 17 completed the study. The study arms were: 1) group-based Form-Focused running using ChiRunning (enrolled, n =10; completed, n=7); 2) group-based conventional running (enrolled, n=6; completed, n=4); 3) self-directed training with educational materials (enrolled, n =6; completed, n=6). The training schedule was prescribed for 8 weeks with 4 weeks of follow-up. All subjects completed overground running motion analyses before and after training. Outcomes Ankle, knee, hip joint peak moments and powers; Average vertical loading rate (AVLR), impact peak, cadence, stride length, strike index, and stride reach. Paired T-tests were used to compare differences with-in groups over-time. Results Form-Focused group reduced their Stride Reach (P = .047) after the training but not the other groups. Form-Focused group showed a close to significant reduction in knee adduction moment (P = .051) and a reduction in the peak ankle eversion moment (P = .027). Self-Directed group showed an increase in the running speed, (P =.056) and increases in ankle and knee joint powers and moments. Conclusions There are differences in the changes in running biomechanics between individuals trained in running form that emphazies mid-foot strike, higher cadence, and shorter stride compared to those not trained in the thise technique. These differences may be associated with reduced lower extremity stress in individuals trained in this running form but future studies are needed to confirm these findings in larger samples. PMID:25633634

Parallel ALLSPD-3D: Speeding Up Combustor Analysis Via Parallel Processing

NASA Technical Reports Server (NTRS)

Fricker, David M.

1997-01-01

The ALLSPD-3D Computational Fluid Dynamics code for reacting flow simulation was run on a set of benchmark test cases to determine its parallel efficiency. These test cases included non-reacting and reacting flow simulations with varying numbers of processors. Also, the tests explored the effects of scaling the simulation with the number of processors in addition to distributing a constant size problem over an increasing number of processors. The test cases were run on a cluster of IBM RS/6000 Model 590 workstations with ethernet and ATM networking plus a shared memory SGI Power Challenge L workstation. The results indicate that the network capabilities significantly influence the parallel efficiency, i.e., a shared memory machine is fastest and ATM networking provides acceptable performance. The limitations of ethernet greatly hamper the rapid calculation of flows using ALLSPD-3D.

Causality links among renewable energy consumption, CO2 emissions, and economic growth in Africa: evidence from a panel ARDL-PMG approach.

PubMed

Attiaoui, Imed; Toumi, Hassen; Ammouri, Bilel; Gargouri, Ilhem

2017-05-01

This research examines the causality (For the remainder of the paper, the notion of causality refers to Granger causality.) links among renewable energy consumption (REC), CO 2 emissions (CE), non-renewable energy consumption (NREC), and economic growth (GDP) using an autoregressive distributed lag model based on the pooled mean group estimation (ARDL-PMG) and applying Granger causality tests for a panel consisting of 22 African countries for the period between 1990 and 2011. There is unidirectional and irreversible short-run causality from CE to GDP. The causal direction between CE and REC is unobservable over the short-term. Moreover, we find unidirectional, short-run causality from REC to GDP. When testing per pair of variables, there are short-run bidirectional causalities among REC, CE, and GDP. However, if we add CE to the variables REC and NREC, the causality to GDP is observable, and causality from the pair REC and NREC to economic growth is neutral. Likewise, if we add NREC to the variables GDP and REC, there is causality. There are bidirectional long-run causalities among REC, CE, and GDP, which supports the feedback assumption. Causality from GDP to REC is not strong for the panel. If we test per pair of variables, the strong causality from GDP and CE to REC is neutral. The long-run PMG estimates show that NREC and gross domestic product increase CE, whereas REC decreases CE.

Cumulative loads increase at the knee joint with slow-speed running compared to faster running: a biomechanical study.

PubMed

Petersen, Jesper; Sørensen, Henrik; Nielsen, Rasmus Østergaard

2015-04-01

Biomechanical cross-sectional study. To investigate the hypothesis that the cumulative load at the knee during running increases as running speed decreases. The knee joint load per stride decreases as running speed decreases. However, by decreasing running speed, the number of strides per given distance is increased. Running a given distance at a slower speed may increase the cumulative load at the knee joint compared with running the same distance at a higher speed, hence increasing the risk of running-related injuries in the knee. Kinematic and ground reaction force data were collected from 16 recreational runners, during steady-state running with a rearfoot strike pattern at 3 different speeds (mean ± SD): 8.02 ± 0.17 km/h, 11.79 ± 0.21 km/h, and 15.78 ± 0.22 km/h. The cumulative load (cumulative impulse) over a 1000-m distance was calculated at the knee joint on the basis of a standard 3-D inverse-dynamics approach. Based on a 1000-m running distance, the cumulative load at the knee was significantly higher at a slow running speed than at a high running speed (relative difference, 80%). The mean load per stride at the knee increased significantly across all biomechanical parameters, except impulse, following an increase in running speed. Slow-speed running decreases knee joint loads per stride and increases the cumulative load at the knee joint for a given running distance compared to faster running. The primary reason for the increase in cumulative load at slower speeds is an increase in number of strides needed to cover the same distance.

The Effects of a Duathlon Simulation on Ventilatory Threshold and Running Economy

PubMed Central

Berry, Nathaniel T.; Wideman, Laurie; Shields, Edgar W.; Battaglini, Claudio L.

2016-01-01

Multisport events continue to grow in popularity among recreational, amateur, and professional athletes around the world. This study aimed to determine the compounding effects of the initial run and cycling legs of an International Triathlon Union (ITU) Duathlon simulation on maximal oxygen uptake (VO2max), ventilatory threshold (VT) and running economy (RE) within a thermoneutral, laboratory controlled setting. Seven highly trained multisport athletes completed three trials; Trial-1 consisted of a speed only VO2max treadmill protocol (SOVO2max) to determine VO2max, VT, and RE during a single-bout run; Trial-2 consisted of a 10 km run at 98% of VT followed by an incremental VO2max test on the cycle ergometer; Trial-3 consisted of a 10 km run and 30 km cycling bout at 98% of VT followed by a speed only treadmill test to determine the compounding effects of the initial legs of a duathlon on VO2max, VT, and RE. A repeated measures ANOVA was performed to determine differences between variables across trials. No difference in VO2max, VT (%VO2max), maximal HR, or maximal RPE was observed across trials. Oxygen consumption at VT was significantly lower during Trial-3 compared to Trial-1 (p = 0.01). This decrease was coupled with a significant reduction in running speed at VT (p = 0.015). A significant interaction between trial and running speed indicate that RE was significantly altered during Trial-3 compared to Trial-1 (p < 0.001). The first two legs of a laboratory based duathlon simulation negatively impact VT and RE. Our findings may provide a useful method to evaluate multisport athletes since a single-bout incremental treadmill test fails to reveal important alterations in physiological thresholds. Key points Decrease in relative oxygen uptake at VT (ml·kg-1·min-1) during the final leg of a duathlon simulation, compared to a single-bout maximal run. We observed a decrease in running speed at VT during the final leg of a duathlon simulation; resulting in an increase of more than 2 minutes to complete a 5 km run. During our study, highly trained athletes were unable to complete the final 5 km run at the same intensity that they completed the initial 10 km run (in a laboratory setting). A better understanding, and determination, of training loads during multisport training may help to better periodize training programs; additional research is required. PMID:27274661

Validation of Supersonic Film Cooling Modeling for Liquid Rocket Engine Applications

NASA Technical Reports Server (NTRS)

Morris, Christopher I.; Ruf, Joseph H.

2010-01-01

Topics include: upper stage engine key requirements and design drivers; Calspan "stage 1" results, He slot injection into hypersonic flow (air); test articles for shock generator diagram, slot injector details, and instrumentation positions; test conditions; modeling approach; 2-d grid used for film cooling simulations of test article; heat flux profiles from 2-d flat plate simulations (run #4); heat flux profiles from 2-d backward facing step simulations (run #43); isometric sketch of single coolant nozzle, and x-z grid of half-nozzle domain; comparison of 2-d and 3-d simulations of coolant nozzles (run #45); flowfield properties along coolant nozzle centerline (run #45); comparison of 3-d CFD nozzle flow calculations with experimental data; nozzle exit plane reduced to linear profile for use in 2-d film-cooling simulations (run #45); synthetic Schlieren image of coolant injection region (run #45); axial velocity profiles from 2-d film-cooling simulation (run #45); coolant mass fraction profiles from 2-d film-cooling simulation (run #45); heat flux profiles from 2-d film cooling simulations (run #45); heat flux profiles from 2-d film cooling simulations (runs #47, #45, and #47); 3-d grid used for film cooling simulations of test article; heat flux contours from 3-d film-cooling simulation (run #45); and heat flux profiles from 3-d and 2-d film cooling simulations (runs #44, #46, and #47).

78 FR 15403 - Agency Information Collection Activities; Proposed Collection; Comment Request; Company-Run...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-11

... Activities; Proposed Collection; Comment Request; Company-Run Annual Stress Test Reporting Template and... Federal savings associations titled, ``Company-Run Annual Stress Test Reporting Template and Documentation....occ.gov/tools-forms/forms/bank-operations/stress-test-reporting.html ). SUPPLEMENTARY INFORMATION: The...

Lubricant Effects on Efficiency of a Helicopter Transmission

NASA Technical Reports Server (NTRS)

Mitchell, A. M.; Coy, J. J.

1982-01-01

Eleven different lubricants were used in efficiency tests conducted on the OH-58A helicopter main transmission using the NASA Lewis Research Center's 500 hp torque regenerative helicopter transmission test stand. Tests were run at oil-in temperatures of 355 K and 372 K. The efficiency was calculated from a heat balance on the water running through an oil to water heat exchanger which the transmission was heavily insulated. Results show an efficiency range from 98.3% to 98.8% which is a 50% variation relative to the losses associated with the maximum efficiency measured. For a given lubricant, the efficiency increased as temperature increased and viscosity decreased. There were two exceptions which could not be explained. Between lubricants, efficiency was not correlated with viscosity. There were relatively large variations in efficiency with the different lubricants whose viscosity generally fell in the 5 to 7 centistoke range. The lubricants had no significant effect on the vibration signature of the transmission.

Voluntary wheel-running attenuates insulin and weight gain and affects anxiety-like behaviors in C57BL6/J mice exposed to a high-fat diet.

PubMed

Hicks, Jasmin A; Hatzidis, Aikaterini; Arruda, Nicole L; Gelineau, Rachel R; De Pina, Isabella Monteiro; Adams, Kenneth W; Seggio, Joseph A

2016-09-01

It is widely accepted that lifestyle plays a crucial role on the quality of life in individuals, particularly in western societies where poor diet is correlated to alterations in behavior and the increased possibility of developing type-2 diabetes. While exercising is known to produce improvements to overall health, there is conflicting evidence on how much of an effect exercise has staving off the development of type-2 diabetes or counteracting the effects of diet on anxiety. Thus, this study investigated the effects of voluntary wheel-running access on the progression of diabetes-like symptoms and open field and light-dark box behaviors in C57BL/6J mice fed a high-fat diet. C57BL/6J mice were placed into either running-wheel cages or cages without a running-wheel, given either regular chow or a high-fat diet, and their body mass, food consumption, glucose tolerance, insulin and c-peptide levels were measured. Mice were also exposed to the open field and light-dark box tests for anxiety-like behaviors. Access to a running-wheel partially attenuated the obesity and hyperinsulinemia associated with high-fat diet consumption in these mice, but did not affect glucose tolerance or c-peptide levels. Wheel-running strongly increased anxiety-like and decreased explorative-like behaviors in the open field and light-dark box, while high-fat diet consumption produced smaller increases in anxiety. These results suggest that voluntary wheel-running can assuage some, but not all, of the physiological problems associated with high-fat diet consumption, and can modify anxiety-like behaviors regardless of diet consumed. Copyright © 2016 Elsevier B.V. All rights reserved.

On the effect of unsupported sleepers on the dynamic behaviour of a railway track

NASA Astrophysics Data System (ADS)

Zhu, J. Y.; Thompson, D. J.; Jones, C. J. C.

2011-09-01

The effect of unsupported sleepers on the dynamic behaviour of a railway track is studied based on vehicle-track dynamic interaction theory, using a model of the track as a Timoshenko beam supported on a periodic elastic foundation. Considering the vehicle's running speed and the number of unsupported sleepers, the track dynamic characteristics are investigated and verified in the time and frequency domains by experiments on a 1:5 scale model wheel-rail test rig. The results show that when hanging sleepers are present, leading to a discontinuous and irregular track support, additional wheel-rail interaction forces are generated. These forces increase as further sleepers become unsupported and as the vehicle's running speed increases. The adjacent supports experience increased dynamic forces which will lead to further deterioration of track quality and the formation of long wavelength track irregularities, which worsen the vehicles' running stability and riding comfort. Stationary transfer functions measurements of the dynamic behaviour of the track are also presented to support the findings.

Rod pumping and proppant flowback at the Lost Hills Field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, I.G.

1995-12-31

Proppant flowback from hydraulically fractured wells can lead to sand wear on the pump barrel and plunger and increased pulling costs on rod pumped wells. Two approaches for lengthening run times of the pumps were tried. One approach was to install pumps that will allow production of a sand laden fluid. Pressure actuated plunger (PAP) pumps were field tested and showed an average increase of 81.6% in run time. These split ring wiper pumps clean the barrel of sand prior to the passing of the plunger. The other approach was to keep the sand and from entering the pumps. Whenmore » down hole filters were utilized, run life of the pumps with the filters increases 135%. Well pulling cost savings of $11.91 per well-day and $9.24 per well-day are documented for the PAP pumps and filters, respectively. Application guidelines based on the sand loading rate and gross liquid production of the wells are presented, as well as some operational experiences.« less

Effects of medially wedged foot orthoses on knee and hip joint running mechanics in females with and without patellofemoral pain syndrome.

PubMed

Boldt, Andrew R; Willson, John D; Barrios, Joaquin A; Kernozek, Thomas W

2013-02-01

We examined the effects of medially wedged foot orthoses on knee and hip joint mechanics during running in females with and without patellofemoral pain syndrome (PFPS). We also tested if these effects depend on standing calcaneal eversion angle. Twenty female runners with and without PFPS participated. Knee and hip joint transverse and frontal plane peak angle, excursion, and peak internal knee and hip abduction moment were calculated while running with and without a 6° full-length medially wedged foot orthoses. Separate 3-factor mixed ANOVAs (group [PFPS, control] x condition [medial wedge, no medial wedge] x standing calcaneal angle [everted, neutral, inverted]) were used to test the effect of medially wedged orthoses on each dependent variable. Knee abduction moment increased 3% (P = .03) and hip adduction excursion decreased 0.6° (P < .01) using medially wedged foot orthoses. No significant group x condition or calcaneal angle x condition effects were observed. The addition of medially wedged foot orthoses to standardized running shoes had minimal effect on knee and hip joint mechanics during running thought to be associated with the etiology or exacerbation of PFPS symptoms. These effects did not appear to depend on injury status or standing calcaneal posture.

Deployable Aeroshell Flexible Thermal Protection System Testing

NASA Technical Reports Server (NTRS)

Hughes, Stephen J.; Ware, Joanne S.; DelCorso, Joseph A.; Lugo, Rafael A.

2009-01-01

Deployable aeroshells offer the promise of achieving larger aeroshell surface areas for entry vehicles than otherwise attainable without deployment. With the larger surface area comes the ability to decelerate high-mass entry vehicles at relatively low ballistic coefficients. However, for an aeroshell to perform even at the low ballistic coefficients attainable with deployable aeroshells, a flexible thermal protection system (TPS) is required that is capable of surviving reasonably high heat flux and durable enough to survive the rigors of construction handling, high density packing, deployment, aerodynamic loading and aerothermal heating. The Program for the Advancement of Inflatable Decelerators for Atmospheric Entry (PAIDAE) is tasked with developing the technologies required to increase the technology readiness level (TRL) of inflatable deployable aeroshells, and one of several of the technologies PAIDAE is developing for use on inflatable aeroshells is flexible TPS. Several flexible TPS layups were designed, based on commercially available materials, and tested in NASA Langley Research Center's 8 Foot High Temperature Tunnel (8ft HTT). The TPS layups were designed for, and tested at three different conditions that are representative of conditions seen in entry simulation analyses of inflatable aeroshell concepts. Two conditions were produced in a single run with a sting-mounted dual wedge test fixture. The dual wedge test fixture had one row of sample mounting locations (forward) at about half the running length of the top surface of the wedge. At about two thirds of the running length of the wedge, a second test surface drafted up at five degrees relative to the first test surface established the remaining running length of the wedge test fixture. A second row of sample mounting locations (aft) was positioned in the middle of the running length of the second test surface. Once the desired flow conditions were established in the test section the dual wedge test fixture, oriented at 5 degrees angle of attack down, was injected into the flow. In this configuration the aft sample mounting location was subjected to roughly twice the heat flux and surface pressure of the forward mounting location. The tunnel was run at two different conditions for the test series: 1) 'Low Pressure', and 2) 'High Pressure'. At 'Low Pressure' conditions the TPS layups were tested at 6W/cm2 and 11W/cm2 while at 'High Pressure' conditions the TPS layups were tested at 11W/cm2 and 20W/cm2. This paper details the test configuration of the TPS samples in the 8Ft HTT, the sample holder assembly, TPS sample layup construction, sample instrumentation, results from this testing, as well as lessons learned.

Criterion-Related Validity of the Distance- and Time-Based Walk/Run Field Tests for Estimating Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis.

PubMed

Mayorga-Vega, Daniel; Bocanegra-Parrilla, Raúl; Ornelas, Martha; Viciana, Jesús

2016-01-01

The main purpose of the present meta-analysis was to examine the criterion-related validity of the distance- and time-based walk/run tests for estimating cardiorespiratory fitness among apparently healthy children and adults. Relevant studies were searched from seven electronic bibliographic databases up to August 2015 and through other sources. The Hunter-Schmidt's psychometric meta-analysis approach was conducted to estimate the population criterion-related validity of the following walk/run tests: 5,000 m, 3 miles, 2 miles, 3,000 m, 1.5 miles, 1 mile, 1,000 m, ½ mile, 600 m, 600 yd, ¼ mile, 15 min, 12 min, 9 min, and 6 min. From the 123 included studies, a total of 200 correlation values were analyzed. The overall results showed that the criterion-related validity of the walk/run tests for estimating maximum oxygen uptake ranged from low to moderate (rp = 0.42-0.79), with the 1.5 mile (rp = 0.79, 0.73-0.85) and 12 min walk/run tests (rp = 0.78, 0.72-0.83) having the higher criterion-related validity for distance- and time-based field tests, respectively. The present meta-analysis also showed that sex, age and maximum oxygen uptake level do not seem to affect the criterion-related validity of the walk/run tests. When the evaluation of an individual's maximum oxygen uptake attained during a laboratory test is not feasible, the 1.5 mile and 12 min walk/run tests represent useful alternatives for estimating cardiorespiratory fitness. As in the assessment with any physical fitness field test, evaluators must be aware that the performance score of the walk/run field tests is simply an estimation and not a direct measure of cardiorespiratory fitness.

Corticosterone administration in drinking water decreases high-fat diet intake but not preference in male rats

PubMed Central

Boersma, Gretha J.; Tamashiro, Kellie L.; Moran, Timothy H.

2016-01-01

One of the mechanisms through which regular exercise contributes to weight maintenance could be by reducing intake and preference for high-fat (HF) diets. Indeed, we previously demonstrated that wheel-running rats robustly reduced HF diet intake and preference. The reduced HF diet preference by wheel running can be so profound that the rats consumed only the chow diet and completely avoided the HF diet. Because previous research indicates that exercise activates the hypothalamic-pituitary-adrenal axis and increases circulating levels of corticosterone, this study tested the hypothesis that elevation of circulating corticosterone is involved in wheel running-induced reduction in HF diet preference in rats. Experiment 1 measured plasma corticosterone levels under sedentary and wheel-running conditions in the two-diet-choice (high-carbohydrate chow vs. HF) feeding regimen. The results revealed that plasma corticosterone is significantly increased and positively correlated with the levels of running in wheel-running rats with two-diet choice. Experiments 2 and 3 determined whether elevated corticosterone without wheel running is sufficient to reduce HF diet intake and preference. Corticosterone was elevated by adding it to the drinking water. Compared with controls, corticosterone-drinking rats had reduced HF diet intake and body weight, but the HF diet preference between groups did not differ. The results of this study support a role for elevated corticosterone on the reduced HF diet intake during wheel running. The elevation of corticosterone alone, however, is not sufficient to produce a robust reduction in HF diet preference. PMID:26818055

Corticosterone administration in drinking water decreases high-fat diet intake but not preference in male rats.

PubMed

Boersma, Gretha J; Tamashiro, Kellie L; Moran, Timothy H; Liang, Nu-Chu

2016-04-15

One of the mechanisms through which regular exercise contributes to weight maintenance could be by reducing intake and preference for high-fat (HF) diets. Indeed, we previously demonstrated that wheel-running rats robustly reduced HF diet intake and preference. The reduced HF diet preference by wheel running can be so profound that the rats consumed only the chow diet and completely avoided the HF diet. Because previous research indicates that exercise activates the hypothalamic-pituitary-adrenal axis and increases circulating levels of corticosterone, this study tested the hypothesis that elevation of circulating corticosterone is involved in wheel running-induced reduction in HF diet preference in rats.Experiment 1 measured plasma corticosterone levels under sedentary and wheel-running conditions in the two-diet-choice (high-carbohydrate chow vs. HF) feeding regimen. The results revealed that plasma corticosterone is significantly increased and positively correlated with the levels of running in wheel-running rats with two-diet choice.Experiments 2 and 3 determined whether elevated corticosterone without wheel running is sufficient to reduce HF diet intake and preference. Corticosterone was elevated by adding it to the drinking water. Compared with controls, corticosterone-drinking rats had reduced HF diet intake and body weight, but the HF diet preference between groups did not differ. The results of this study support a role for elevated corticosterone on the reduced HF diet intake during wheel running. The elevation of corticosterone alone, however, is not sufficient to produce a robust reduction in HF diet preference. Copyright © 2016 the American Physiological Society.

Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice.

PubMed

Jiang, Lin; Ma, Jing; Zhang, Yi; Zhou, Chun-Ni; Zhang, Lei; Chao, Feng-Lei; Chen, Lin-Mu; Jiang, Rong; Wu, Hong; Tang, Yong

2018-08-01

To investigate the effect of running exercise on the number of the neurons in the hippocampus of young APP/PS1 mice, twenty 6-month-old male APP/ PS1 transgenic mice were randomly divided into the APP/PS1 control (AD control) group and the APP/PS1 running (AD running) group (10 mice per group), and ten wild-type mice of the littermate were regarded as the wild-type (WT) group. The AD running mice ran on motorized treadmill machiene for 4 months, while the WT mice and AD control mice were housed in standard condition without running. Then, Morris water maze tests (MWM) were used to assess the special learning and memory abilities of mice in three groups. The stereological methods were used to quantitatively evaluate the volume of the hippocampus, CA1/2, CA3 and the dentate gyrus (DG) and count the number of the neurons in CA1/2, CA3 and DG. We found that 4-month running effectively shortened the escape latency of young APP/PS1 control mice in MWM. More importantly, 4-month running effectively increased the volumes of the hippocampus, CA1/2, CA3 and DG and increased the number of neurons in CA1/2, CA3 and DG in young APP/PS1 mice. The present results suggested that 4-month running has significant beneficial effects on the spatial learning and memory capacities of young APP/PS1 mice and could delay the progress of atrophy of hippocampus and the neuron death in CA1/2, CA3 and DG in young APP/PS1 mice. Copyright © 2018 Elsevier B.V. All rights reserved.

Intensity related changes of running economy in recreational level distance runners.

PubMed

Engeroff, Tobias; Bernardi, Andreas; Niederer, Daniel; Wilke, Jan; Vogt, Lutz; Banzer, Winfried

2017-09-01

Running economy (RE) is often described as a key demand of running performance. The variety of currently used assessment methods with different running intensities and outcomes restricts interindividual comparability of RE in recreational level runners. The purpose of this study was to compare the influence of RE, assessed as oxygen cost (OC) and caloric unit cost (CUC), on running speed at individual physiological thresholds. Eighteen recreational runners performed: 1) a graded exercise test to estimate first ventilatory threshold (VT1), respiratory compensation point (RCP) and maximal oxygen uptake (VO2max); 2) discontinuous RE assessment to determine relative OC in milliliters per kilogram per kilometer (mL/kg/km) and CUC in kilocalories per kilogram per kilometer (kcal/kg/km) at three different running intensities: VT1, RCP and at a third standardized reference point (TP) in between. OC (mL/kg/km; at VT1: 235.4±26.2; at TP: 227.8±23.4; at RCP: 224.9±21.9) and CUC (kcal/kg/km at VT1: 1.18±0.13; at TP: 1.14±0.12; at RCP: 1.13±0.11) decreased with increasing intensities (P≤0.01). Controlling for the influence of sex OC and CUC linearly correlated with running speed at RCP and VO2max (P≤0.01). RE, even assessed at low intensity, is strongly related to running performance in recreational athletes. Both calculation methods used (OC and CUC) are sensitive for monitoring intensity related changes of substrate utilization. RE values decreased with higher running intensity indicating an increase of anaerobic and subsequent decrease of aerobic substrate utilization.

Anthropometric, Sprint, and High-Intensity Running Profiles of English Academy Rugby Union Players by Position.

PubMed

Darrall-Jones, Joshua D; Jones, Ben; Till, Kevin

2016-05-01

The purpose of this study was to evaluate the anthropometric, sprint, and high-intensity running profiles of English academy rugby union players by playing positions, and to investigate the relationships between anthropometric, sprint, and high-intensity running characteristics. Data were collected from 67 academy players after the off-season period and consisted of anthropometric (height, body mass, sum of 8 skinfolds [∑SF]), 40-m linear sprint (5-, 10-, 20-, and 40-m splits), the Yo-Yo intermittent recovery test level 1 (Yo-Yo IRTL-1), and the 30-15 intermittent fitness test (30-15 IFT). Forwards displayed greater stature, body mass, and ∑SF; sprint times and sprint momentum, with lower high-intensity running ability and sprint velocities than backs. Comparisons between age categories demonstrated body mass and sprint momentum to have the largest differences at consecutive age categories for forwards and backs; whereas 20-40-m sprint velocity was discriminate for forwards between under 16s, 18s, and 21s. Relationships between anthropometric, sprint velocity, momentum, and high-intensity running ability demonstrated body mass to negatively impact on sprint velocity (10 m; r = -0.34 to -0.46) and positively affect sprint momentum (e.g., 5 m; r = 0.85-0.93), with large to very large negative relationships with the Yo-Yo IRTL-1 (r = -0.65 to -0.74) and 30-15 IFT (r = -0.59 to -0.79). These findings suggest that there are distinct anthropometric, sprint, and high-intensity running ability differences between and within positions in junior rugby union players. The development of sprint and high-intensity running ability may be impacted by continued increases in body mass as there seems to be a trade-off between momentum, velocity, and the ability to complete high-intensity running.

CHANGES IN THE ANAEROBIC THRESHOLD IN AN ANNUAL CYCLE OF SPORT TRAINING OF YOUNG SOCCER PLAYERS

PubMed Central

Andrzejewski, M.; Wieczorek, A.; Barinow-Wojewódzki, A.; Jadczak, Ł.; Adrian, S.; Pietrzak, M.; Wieczorek, S.

2013-01-01

The aim of the study was to assess changes in the anaerobic threshold of young soccer players in an annual training cycle. A group of highly trained 15-18 year old players of KKS Lech Poznań were tested. The tests included an annual training macrocycle, and its individual stages resulted from the time structure of the sports training. In order to assess the level of exercise capacities of the players, a field exercise test of increasing intensity was carried out on a soccer pitch. The test made it possible to determine the 4 millimolar lactate threshold (T LA 4 mmol · l-1) on the basis of the lactate concentration in blood [LA], to establish the threshold running speed and the threshold heart rate [HR]. The threshold running speed at the level of the 4 millimolar lactate threshold was established using the two-point form of the equation of a straight line. The obtained indicators of the threshold running speed allowed for precise establishment of effort intensity used in individual training in developing aerobic endurance. In order to test the significance of differences in mean values between four dates of tests, a non-parametric Friedman ANOVA test was used. The significance of differences between consecutive dates of tests was determined using a post-hoc Friedman ANOVA test. The tests showed significant differences in values of selected indicators determined at the anaerobic threshold in various stages of an annual training cycle of young soccer players. The most beneficial changes in terms of the threshold running speed were noted on the fourth date of tests, when the participants had the highest values of 4.01 m · s-1 for older juniors, and 3.80 m · s-1 for younger juniors. This may be indicative of effective application of an individualized programme of training loads and of good preparation of teams for competition in terms of players’ aerobic endurance. PMID:24744480

Changes in the anaerobic threshold in an annual cycle of sport training of young soccer players.

PubMed

Sliwowski, R; Andrzejewski, M; Wieczorek, A; Barinow-Wojewódzki, A; Jadczak, L; Adrian, S; Pietrzak, M; Wieczorek, S

2013-06-01

The aim of the study was to assess changes in the anaerobic threshold of young soccer players in an annual training cycle. A group of highly trained 15-18 year old players of KKS Lech Poznań were tested. The tests included an annual training macrocycle, and its individual stages resulted from the time structure of the sports training. In order to assess the level of exercise capacities of the players, a field exercise test of increasing intensity was carried out on a soccer pitch. The test made it possible to determine the 4 millimolar lactate threshold (T LA 4 mmol · l(-1)) on the basis of the lactate concentration in blood [LA], to establish the threshold running speed and the threshold heart rate [HR]. The threshold running speed at the level of the 4 millimolar lactate threshold was established using the two-point form of the equation of a straight line. The obtained indicators of the threshold running speed allowed for precise establishment of effort intensity used in individual training in developing aerobic endurance. In order to test the significance of differences in mean values between four dates of tests, a non-parametric Friedman ANOVA test was used. The significance of differences between consecutive dates of tests was determined using a post-hoc Friedman ANOVA test. The tests showed significant differences in values of selected indicators determined at the anaerobic threshold in various stages of an annual training cycle of young soccer players. The most beneficial changes in terms of the threshold running speed were noted on the fourth date of tests, when the participants had the highest values of 4.01 m · s(-1) for older juniors, and 3.80 m · s(-1) for younger juniors. This may be indicative of effective application of an individualized programme of training loads and of good preparation of teams for competition in terms of players' aerobic endurance.

Existing agricultural ecosystem in China leads to environmental pollution: an econometric approach.

PubMed

Hongdou, Lei; Shiping, Li; Hao, Li

2018-06-17

Sustainable agriculture ensures food security and prevents starvation. However, the need to meet the increasing food demands of the growing population has led to poor and unsustainable agricultural practices, which promote environmental degradation. Given the contributions of agricultural ecosystems to environmental pollution, we investigated the impact of the agricultural ecosystem on environmental pollution in China using time series data from 1960 to 2014. We employed several methods for econometric analysis including the unit root test, Johansen test of cointegration, Granger causality test, and vector error correction model. Evidence based on the long-run elasticity indicates that a 1% increase in the emissions of carbon dioxide (CO 2 ) equivalent to nitrous oxide from synthetic fertilizers will increase the emissions of CO 2 by 1.52% in the long run. Similarly, a 1% increase in the area of harvested rice paddy, cereal production, biomass of burned crop residues, and agricultural GDP will increase the carbon dioxide emissions by 0.85, 0.63, 0.37, and 0.22%, respectively. The estimated results indicate that there are long-term equilibrium relationships among the selected variables considered for the agricultural ecosystem and carbon dioxide emissions. In particular, we identified bidirectional causal associations between CO 2 emissions, biomass of burned crop residues, and cereal production. Graphical abstract ᅟ.

The CMS Tier0 goes cloud and grid for LHC Run 2

DOE PAGES

Hufnagel, Dirk

2015-12-23

In 2015, CMS will embark on a new era of collecting LHC collisions at unprecedented rates and complexity. This will put a tremendous stress on our computing systems. Prompt Processing of the raw data by the Tier-0 infrastructure will no longer be constrained to CERN alone due to the significantly increased resource requirements. In LHC Run 2, we will need to operate it as a distributed system utilizing both the CERN Cloud-based Agile Infrastructure and a significant fraction of the CMS Tier-1 Grid resources. In another big change for LHC Run 2, we will process all data using the multi-threadedmore » framework to deal with the increased event complexity and to ensure efficient use of the resources. Furthermore, this contribution will cover the evolution of the Tier-0 infrastructure and present scale testing results and experiences from the first data taking in 2015.« less

Electrochemical disinfection of repeatedly recycled blackwater in a free-standing, additive-free toilet.

PubMed

Hawkins, Brian T; Sellgren, Katelyn L; Klem, Ethan J D; Piascik, Jeffrey R; Stoner, Brian R

2017-11-01

Decentralized, energy-efficient waste water treatment technologies enabling water reuse are needed to sustainably address sanitation needs in water- and energy-scarce environments. Here, we describe the effects of repeated recycling of disinfected blackwater (as flush liquid) on the energy required to achieve full disinfection with an electrochemical process in a prototype toilet system. The recycled liquid rapidly reached a steady state with total solids reliably ranging between 0.50 and 0.65% and conductivity between 20 and 23 mS/cm through many flush cycles over 15 weeks. The increase in accumulated solids was associated with increased energy demand and wide variation in the free chlorine contact time required to achieve complete disinfection. Further studies on the system at steady state revealed that running at higher voltage modestly improves energy efficiency, and established running parameters that reliably achieve disinfection at fixed run times. These results will guide prototype testing in the field.

Is trade openness good for environment in South Korea? The role of non-fossil electricity consumption.

PubMed

Zhang, Shun

2018-04-01

The paper investigates the linkage of carbon dioxide (CO 2 ) emissions, per capita real output, share of non-fossil electricity consumption, and trade openness in South Korea from 1971 to 2013. The empirical results indicate that the environmental Kuznets curve (EKC) is supported by autoregressive distributed lag (ARDL) test. Both short- and long-run estimates indicate that increasing non-fossil electricity consumption can mitigate environmental degradation, and increasing trade aggravates carbon dioxide emissions. By Granger causality, long-run causalities are found in both equations of CO 2 emissions and trade openness, as well as exports and imports. In the short-run, evidence indicates feedback linkage between output and trade, unidirectional linkages from trade to emissions, from emissions to output, and from output to non-fossil electricity use. Therefore, South Korea should strengthen the sustainable economy, consume clean energy, and develop green trade.

The CMS TierO goes Cloud and Grid for LHC Run 2

NASA Astrophysics Data System (ADS)

Hufnagel, Dirk

2015-12-01

In 2015, CMS will embark on a new era of collecting LHC collisions at unprecedented rates and complexity. This will put a tremendous stress on our computing systems. Prompt Processing of the raw data by the Tier-0 infrastructure will no longer be constrained to CERN alone due to the significantly increased resource requirements. In LHC Run 2, we will need to operate it as a distributed system utilizing both the CERN Cloud-based Agile Infrastructure and a significant fraction of the CMS Tier-1 Grid resources. In another big change for LHC Run 2, we will process all data using the multi-threaded framework to deal with the increased event complexity and to ensure efficient use of the resources. This contribution will cover the evolution of the Tier-0 infrastructure and present scale testing results and experiences from the first data taking in 2015.

78 FR 62942 - Agency Information Collection Activities; Proposed Collection; Comment Request; Company-Run...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... Activities; Proposed Collection; Comment Request; Company-Run Annual Stress Test Reporting Template and... Federal savings associations titled, ``Company-Run Annual Stress Test Reporting Template and Documentation... Web site under Tools and Forms ( http://www.occ.gov/tools-forms/forms/bank-operations/stress-test...

IR Camera Report for the 7 Day Production Test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holloway, Michael Andrew

2016-02-22

The following report gives a summary of the IR camera performance results and data for the 7 day production run that occurred from 10 Sep 2015 thru 16 Sep 2015. During this production run our goal was to see how well the camera performed its task of monitoring the target window temperature with our improved alignment procedure and emissivity measurements. We also wanted to see if the increased shielding would be effective in protecting the camera from damage and failure.

Using wheel availability to shape running behavior of the rat towards improved behavioral and neurobiological outcomes.

PubMed

Basso, Julia C; Morrell, Joan I

2017-10-01

Though voluntary wheel running (VWR) has been used extensively to induce changes in both behavior and biology, little attention has been given to the way in which different variables influence VWR. This lack of understanding has led to an inability to utilize this behavior to its full potential, possibly blunting its effects on the endpoints of interest. We tested how running experience, sex, gonadal hormones, and wheel apparatus influence VWR in a range of wheel access "doses". VWR increases over several weeks, with females eventually running 1.5 times farther and faster than males. Limiting wheel access can be used as a tool to motivate subjects to run but restricts maximal running speeds attained by the rodents. Additionally, circulating gonadal hormones regulate wheel running behavior, but are not the sole basis of sex differences in running. Limitations from previous studies include the predominate use of males, emphasis on distance run, variable amounts of wheel availability, variable light-dark cycles, and possible food and/or water deprivation. We designed a comprehensive set of experiments to address these inconsistencies, providing data regarding the "microfeatures" of running, including distance run, time spent running, running rate, bouting behavior, and daily running patterns. By systematically altering wheel access, VWR behavior can be finely tuned - a feature that we hypothesize is due to its positive incentive salience. We demonstrate how to maximize VWR, which will allow investigators to optimize exercise-induced changes in their behavioral and/or biological endpoints of interest. Published by Elsevier B.V.

Deconstruction of lignocellulosic biomass with hydrated cerium (III) chloride in water and ethanol

DOE PAGES

Akalin, Mehmet K.; Das, Parthapratim; Alper, Koray; ...

2017-08-08

Lignocellulosic biomass was decomposed to produce crude bio-oil in water and ethanol using hydrated cerium (III) chloride as a catalyst. Use of the catalyst affected not only the yield of crude bio-oil but also the composition of bio-crude for both water and ethanol. The catalyst had a detrimental effect on the crude bio-oil yields obtained from water processing for all runs. However, in ethanol, use of the catalyst improved the crude bio-oil yields in all tested runs. The solid residue yields decreased with the catalyst use in the runs with water but increased in all studies with ethanol, except thosemore » with the shortest tested residence time of 10 min. The highest crude bio-oil yield of 48.2 wt% was obtained at 300 °C using 5 mmol of hydrated cerium (III) chloride at a residence time of 90 min in ethanol. The heating values of the crude bio-oils increased with the catalyst use for both water and ethanol processing. In conclusion, the highest heating value of 33.3 MJ kg –1 was obtained with hydrated cerium (III) chloride at 300 °C and a residence time of 120 min.« less

Deconstruction of lignocellulosic biomass with hydrated cerium (III) chloride in water and ethanol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akalin, Mehmet K.; Das, Parthapratim; Alper, Koray

Lignocellulosic biomass was decomposed to produce crude bio-oil in water and ethanol using hydrated cerium (III) chloride as a catalyst. Use of the catalyst affected not only the yield of crude bio-oil but also the composition of bio-crude for both water and ethanol. The catalyst had a detrimental effect on the crude bio-oil yields obtained from water processing for all runs. However, in ethanol, use of the catalyst improved the crude bio-oil yields in all tested runs. The solid residue yields decreased with the catalyst use in the runs with water but increased in all studies with ethanol, except thosemore » with the shortest tested residence time of 10 min. The highest crude bio-oil yield of 48.2 wt% was obtained at 300 °C using 5 mmol of hydrated cerium (III) chloride at a residence time of 90 min in ethanol. The heating values of the crude bio-oils increased with the catalyst use for both water and ethanol processing. In conclusion, the highest heating value of 33.3 MJ kg –1 was obtained with hydrated cerium (III) chloride at 300 °C and a residence time of 120 min.« less

Small Column Ion Exchange Testing of Superlig 644 for Removal of 137Cs from Hanford Tank Waste Envelope A (Tank 241-AW-101)

DOE Office of Scientific and Technical Information (OSTI.GOV)

DE Kurath; DL Blanchard; JR Bontha

The current BNFL Inc. flow sheet for the pretreatment of the Hanford High-Level tank wastes includes the use of Superlig{reg_sign} materials for the removal of {sup 137}Cs from the aqueous fraction of the waste. The Superlig materials applicable to cesium removal include the cesium selective Superlig 632 and Superlig 644. These materials have been developed and supplied by IBC Advanced Technologies, Inc., American Fork, UT. The work contained in this report involves testing the Superlig 644 ion exchange material in a small dual column system (15 mL each; L/D = 5.7). The sample processed was approximately 2.5 L of dilutedmore » waste [Na{sup +}] = 4.6M from Tank 241-AW-101 (Envelope A). This waste had been previously clarified in a single tube cross-flow filtration unit. All ion exchange process steps were tested including resin bed preparation, loading, feed displacement water rinse, elution and resin regeneration. During the initial run, the lag column did not perform as expected so that the {sup 137}Cs concentration in the effluent composite was above the LAW treatment limits. This required a second column run with the partially decontaminated feed that was conducted at a higher flow rate. A summary of performance measures for both runs is shown in Table S1. The Cs {lambda} values represent a measure of the effective capacity of the SL-644 resin. The Cs {lambda} of 143 for the lead column in run 1 is very similar to the value obtained by the Savannah River Technology Center during Phase 1A testing. The larger Cs {lambda} value for run 2 reflects a general trend for the effective capacity of the SL-644 material to increase as the cesium concentration decreases. The low value for the lag column during the first run indicates that it did not perform as expected. This may have been due to insufficient conditioning of the bed prior to the start of the loading step or to air in the bed that caused channeling. Equilibrium data obtained with batch contacts using the AW-101 Cs IX feed indicates a range for the Cs {lambda} of 80--97. The maximum decontamination factor (DF) for {sup 137}CS is based on analysis of the first samples collected from each column and the concentration in the feed for each run. While the DF's are lower for the second run, this is attributed to the lower {sup 137}Cs concentration in the feed and the increased flowrate. The overall composite DF for run 2 was quite good since both columns functioned well. The overall DF for both runs was 3,000, which provided an effluent with a {sup 137}Cs concentration of 5.89E-02 Ci/m{sup 3} (C/C{sub 0} = 3.3 IE-04). The {sup 137}Cs concentration in the effluent composite was 7.3% of the contract limit for {sup 137}Cs and also below the basis of design limit.« less

Does a run/walk strategy decrease cardiac stress during a marathon in non-elite runners?

PubMed

Hottenrott, Kuno; Ludyga, Sebastian; Schulze, Stephan; Gronwald, Thomas; Jäger, Frank-Stephan

2016-01-01

Although alternating run/walk-periods are often recommended to novice runners, it is unclear, if this particular pacing strategy reduces the cardiovascular stress during prolonged exercise. Therefore, the aim of the study was to compare the effects of two different running strategies on selected cardiac biomarkers as well as marathon performance. Randomized experimental trial in a repeated measure design. Male (n=22) and female subjects (n=20) completed a marathon either with a run/walk strategy or running only. Immediately after crossing the finishing line cardiac biomarkers were assessed in blood taken from the cubital vein. Before (-7 days) and after the marathon (+4 days) subjects also completed an incremental treadmill test. Despite different pacing strategies, run/walk strategy and running only finished the marathon with similar times (04:14:25±00:19:51 vs 04:07:40±00:27:15 [hh:mm:ss]; p=0.377). In both groups, prolonged exercise led to increased B-type natriuretic peptide, creatine kinase MB isoenzyme and myoglobin levels (p<0.001), which returned to baseline 4 days after the marathon. Elevated cTnI concentrations were observable in only two subjects. B-type natriuretic peptide (r=-0.363; p=0.041) and myoglobin levels (r=-0.456; p=0.009) were inversely correlated with the velocity at the individual anaerobic threshold. Run/walk strategy compared to running only reported less muscle pain and fatigue (p=0.006) after the running event. In conclusion, the increase in cardiac biomarkers is a reversible, physiological response to strenuous exercise, indicating temporary stress on the myocyte and skeletal muscle. Although a combined run/walk strategy does not reduce the load on the cardiovascular system, it allows non-elite runners to achieve similar finish times with less (muscle) discomfort. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Health-Related Physical Fitness in Healthy Untrained Men: Effects on VO2max, Jump Performance and Flexibility of Soccer and Moderate-Intensity Continuous Running.

PubMed

Milanović, Zoran; Pantelić, Saša; Sporiš, Goran; Mohr, Magni; Krustrup, Peter

2015-01-01

The purpose of this study was to determine the effects of recreational soccer (SOC) compared to moderate-intensity continuous running (RUN) on all health-related physical fitness components in healthy untrained men. Sixty-nine participants were recruited and randomly assigned to one of three groups, of which sixty-four completed the study: a soccer training group (SOC; n = 20, 34±4 (means±SD) years, 78.1±8.3 kg, 179±4 cm); a running group (RUN; n = 21, 32±4 years, 78.0±5.5 kg, 179±7 cm); or a passive control group (CON; n = 23, 30±3 years, 76.6±12.0 kg, 178±8 cm). The training intervention lasted 12 weeks and consisted of three 60-min sessions per week. All participants were tested for each of the following physical fitness components: maximal aerobic power, minute ventilation, maximal heart rate, squat jump (SJ), countermovement jump with arm swing (CMJ), sit-and-reach flexibility, and body composition. Over the 12 weeks, VO2max relative to body weight increased more (p<0.05) in SOC (24.2%, ES = 1.20) and RUN (21.5%, ES = 1.17) than in CON (-5.0%, ES = -0.24), partly due to large changes in body mass (-5.9, -5.7 and +2.6 kg, p<0.05 for SOC, RUN and CON, respectively). Over the 12 weeks, SJ and CMJ performance increased more (p<0.05) in SOC (14.8 and 12.1%, ES = 1.08 and 0.81) than in RUN (3.3 and 3.0%, ES = 0.23 and 0.19) and CON (0.3 and 0.2%), while flexibility also increased more (p<0.05) in SOC (94%, ES = 0.97) than in RUN and CON (0-2%). In conclusion, untrained men displayed marked improvements in maximal aerobic power after 12 weeks of soccer training and moderate-intensity running, partly due to large decreases in body mass. Additionally soccer training induced pronounced positive effects on jump performance and flexibility, making soccer an effective broad-spectrum fitness training intervention.

Hercules Aerospace flywheel test results

NASA Astrophysics Data System (ADS)

Steele, R. S., Jr.; Babelay, E. F., Jr.; Sutton, B. J.

1981-06-01

The detailed results of the spin test evaluation of the Hercules Aerospace flywheel at the Oak Ridge Flywheel Evaluation Laboratory (ORFEL) are presented. Details of the static evaluation with radiography and measures of weight, inertia and natural frequencies are included. The flywheel was spun four times with the maximum speed being increased with each run. During the final run, the flywheel achieved 372 rps and stored 0.714 kWhr of kinetic energy at 37 Whr/kg. The ultimate speed was limited by a composite transverse strength that was somewhat lower than that used in the design of the flywheel. This resulted in internal cracking of the flywheel and, eventually, the loss of material from the outer circumference.

Torsion and Antero-Posterior Bending in the In Vivo Human Tibia Loading Regimes during Walking and Running

PubMed Central

Yang, Peng-Fei; Sanno, Maximilian; Ganse, Bergita; Koy, Timmo; Brüggemann, Gert-Peter; Müller, Lars Peter; Rittweger, Jörn

2014-01-01

Bending, in addition to compression, is recognized to be a common loading pattern in long bones in animals. However, due to the technical difficulty of measuring bone deformation in humans, our current understanding of bone loading patterns in humans is very limited. In the present study, we hypothesized that bending and torsion are important loading regimes in the human tibia. In vivo tibia segment deformation in humans was assessed during walking and running utilizing a novel optical approach. Results suggest that the proximal tibia primarily bends to the posterior (bending angle: 0.15°–1.30°) and medial aspect (bending angle: 0.38°–0.90°) and that it twists externally (torsion angle: 0.67°–1.66°) in relation to the distal tibia during the stance phase of overground walking at a speed between 2.5 and 6.1 km/h. Peak posterior bending and peak torsion occurred during the first and second half of stance phase, respectively. The peak-to-peak antero-posterior (AP) bending angles increased linearly with vertical ground reaction force and speed. Similarly, peak-to-peak torsion angles increased with the vertical free moment in four of the five test subjects and with the speed in three of the test subjects. There was no correlation between peak-to-peak medio-lateral (ML) bending angles and ground reaction force or speed. On the treadmill, peak-to-peak AP bending angles increased with walking and running speed, but peak-to-peak torsion angles and peak-to-peak ML bending angles remained constant during walking. Peak-to-peak AP bending angle during treadmill running was speed-dependent and larger than that observed during walking. In contrast, peak-to-peak tibia torsion angle was smaller during treadmill running than during walking. To conclude, bending and torsion of substantial magnitude were observed in the human tibia during walking and running. A systematic distribution of peak amplitude was found during the first and second parts of the stance phase. PMID:24732724

Torsion and antero-posterior bending in the in vivo human tibia loading regimes during walking and running.

PubMed

Yang, Peng-Fei; Sanno, Maximilian; Ganse, Bergita; Koy, Timmo; Brüggemann, Gert-Peter; Müller, Lars Peter; Rittweger, Jörn

2014-01-01

Bending, in addition to compression, is recognized to be a common loading pattern in long bones in animals. However, due to the technical difficulty of measuring bone deformation in humans, our current understanding of bone loading patterns in humans is very limited. In the present study, we hypothesized that bending and torsion are important loading regimes in the human tibia. In vivo tibia segment deformation in humans was assessed during walking and running utilizing a novel optical approach. Results suggest that the proximal tibia primarily bends to the posterior (bending angle: 0.15°-1.30°) and medial aspect (bending angle: 0.38°-0.90°) and that it twists externally (torsion angle: 0.67°-1.66°) in relation to the distal tibia during the stance phase of overground walking at a speed between 2.5 and 6.1 km/h. Peak posterior bending and peak torsion occurred during the first and second half of stance phase, respectively. The peak-to-peak antero-posterior (AP) bending angles increased linearly with vertical ground reaction force and speed. Similarly, peak-to-peak torsion angles increased with the vertical free moment in four of the five test subjects and with the speed in three of the test subjects. There was no correlation between peak-to-peak medio-lateral (ML) bending angles and ground reaction force or speed. On the treadmill, peak-to-peak AP bending angles increased with walking and running speed, but peak-to-peak torsion angles and peak-to-peak ML bending angles remained constant during walking. Peak-to-peak AP bending angle during treadmill running was speed-dependent and larger than that observed during walking. In contrast, peak-to-peak tibia torsion angle was smaller during treadmill running than during walking. To conclude, bending and torsion of substantial magnitude were observed in the human tibia during walking and running. A systematic distribution of peak amplitude was found during the first and second parts of the stance phase.

Photobiomodulation Therapy on Physiological and Performance Parameters During Running Tests: Dose-Response Effects.

PubMed

Dellagrana, Rodolfo André; Rossato, Mateus; Sakugawa, Raphael Luiz; Baroni, Bruno Mafredini; Diefenthaeler, Fernando

2018-02-22

This study was aimed at verifying effects of photobiomodulation therapy (PBMT) with different energy doses (15, 30, and 60 J per site) on physiological and performance parameters during running tests. Fifteen male recreational runners participated in a crossover, randomised, double-blind, and placebo-controlled trial. They performed testing protocol in 5 sessions with different treatments: control, placebo, and PBMT with 15, 30 or 60 J per site (14 sites in each lower limb). Physiological and performance variables were assessed during submaximal (at 8 km·h-1 and 9 km·h-1) and maximal running tests. PBMT with 30 J significantly (p<0.05) improved running economy (RE) at 8 and 9 km·h-1 (3.01% and 3.03%, respectively), rate of perceived exertion (RPE) at 8 km·h-1 (7.86%), velocity at VO2MAX (3.07%), peak of velocity (PV) (1.49%), and total time to exhaustion (TTE) (3.41%) compared to placebo. PBMT with 15 J improved RE at 9 km·h-1 (2.98%), RPE at 8 km·h-1 (4.80%), PV (1.33%), TTE (3.06%), and total distance (4.01%) compared to the placebo; while PBMT with 60 J only increased RE at 9 km·h-1 (3.87%) compared to placebo. All PBMT doses positively affected physiological and/or performance parameters; however magnitude-based inference reported that PBMT applied with 30 J led to more beneficial effects than 15 J and 60 J.

Comparative evaluation of the liver in dogs with a splenic mass by using ultrasonography and contrast-enhanced computed tomography

PubMed Central

Irausquin, Roelof A.; Scavelli, Thomas D.; Corti, Lisa; Stefanacci, Joseph D.; DeMarco, Joann; Flood, Shannon; Rohrbach, Barton W.

2008-01-01

Evaluation of dogs with splenic masses to better educate owners as to the extent of the disease is a goal of many research studies. We compared the use of ultrasonography (US) and contrast-enhanced computed tomography (CT) to evaluate the accuracy of detecting hepatic neoplasia in dogs with splenic masses, independently, in series, or in parallel. No significant difference was found between US and CT. If the presence or absence of ascites, as detected with US, was used as a pretest probability of disease in our population, the positive predictive value increased to 94% if the tests were run in series, and the negative predictive value increased to 95% if the tests were run in parallel. The study showed that CT combined with US could be a valuable tool in evaluation of dogs with splenic masses. PMID:18320977

A Monotonic Degradation Assessment Index of Rolling Bearings Using Fuzzy Support Vector Data Description and Running Time

PubMed Central

Shen, Zhongjie; He, Zhengjia; Chen, Xuefeng; Sun, Chuang; Liu, Zhiwen

2012-01-01

Performance degradation assessment based on condition monitoring plays an important role in ensuring reliable operation of equipment, reducing production downtime and saving maintenance costs, yet performance degradation has strong fuzziness, and the dynamic information is random and fuzzy, making it a challenge how to assess the fuzzy bearing performance degradation. This study proposes a monotonic degradation assessment index of rolling bearings using fuzzy support vector data description (FSVDD) and running time. FSVDD constructs the fuzzy-monitoring coefficient ε̄ which is sensitive to the initial defect and stably increases as faults develop. Moreover, the parameter ε̄ describes the accelerating relationships between the damage development and running time. However, the index ε̄ with an oscillating trend disagrees with the irreversible damage development. The running time is introduced to form a monotonic index, namely damage severity index (DSI). DSI inherits all advantages of ε̄ and overcomes its disadvantage. A run-to-failure test is carried out to validate the performance of the proposed method. The results show that DSI reflects the growth of the damages with running time perfectly. PMID:23112591

A monotonic degradation assessment index of rolling bearings using fuzzy support vector data description and running time.

PubMed

Shen, Zhongjie; He, Zhengjia; Chen, Xuefeng; Sun, Chuang; Liu, Zhiwen

2012-01-01

Performance degradation assessment based on condition monitoring plays an important role in ensuring reliable operation of equipment, reducing production downtime and saving maintenance costs, yet performance degradation has strong fuzziness, and the dynamic information is random and fuzzy, making it a challenge how to assess the fuzzy bearing performance degradation. This study proposes a monotonic degradation assessment index of rolling bearings using fuzzy support vector data description (FSVDD) and running time. FSVDD constructs the fuzzy-monitoring coefficient ε⁻ which is sensitive to the initial defect and stably increases as faults develop. Moreover, the parameter ε⁻ describes the accelerating relationships between the damage development and running time. However, the index ε⁻ with an oscillating trend disagrees with the irreversible damage development. The running time is introduced to form a monotonic index, namely damage severity index (DSI). DSI inherits all advantages of ε⁻ and overcomes its disadvantage. A run-to-failure test is carried out to validate the performance of the proposed method. The results show that DSI reflects the growth of the damages with running time perfectly.

Strength and Conditioning Training by the Danish National Handball Team Before an Olympic Tournament.

PubMed

Kvorning, Thue; Hansen, Mikkel R B; Jensen, Kurt

2017-07-01

Kvorning, T, Hansen, MRB, and Jensen, K. Strength and conditioning training by the Danish national handball team before an Olympic tournament. J Strength Cond Res 31(7): 1759-1765, 2017-The physical demands imposed on national team handball teams during the Olympics imply significant physical preparation to improve performance and reduce incidence of injuries. The purpose of this case report was to describe and analyze the strength and conditioning (S&C) training performed by the Danish national handball team before the Beijing Olympic Games. Eight weeks of S&C was divided into 5 weeks emphasizing muscle hypertrophy and long-interval running followed by 3 weeks emphasizing strength, power, and short-interval running. Body mass increased by 1.6% (p < 0.05), whereas body fat decreased by 1.0% (p < 0.05). No differences were seen in countermovement jump or jump-and-reach height (p > 0.05). Agility performance was evaluated by a T-test and improved by 2.5% (p < 0.05). Changes by 6% and 22% were seen in 1 repetition maximum (1RM) bench press and 1RM back squat, respectively. However, only the 1RM bench press increased significantly (p < 0.05). Running performance was tested by the Yo-Yo intermittent recovery test, level 2, and improved by 25% (p < 0.05). In conclusion, during 8 weeks of S&C training before the Beijing Olympics, body composition changed toward more muscle mass, better upper-body strength, better interval running, and agility performance, whereas no changes were seen in jumping or lower-body muscle strength. This case report may be used as a handy script for handball teams preparing for competition. Detailed and periodized S&C training programs for 8 weeks are provided and can be used by teams ranging from moderately to highly trained.

Voluntary Exercise Impairs Initial Delayed Spatial Alternation Performance in Estradiol Treated Ovariectomized Middle-Aged Rats

PubMed Central

Neese, Steven L.; Korol, Donna L.; Schantz, Susan L.

2013-01-01

Estrogens differentially modulate behavior in the adult female rodent. Voluntary exercise can also impact behavior, often reversing age associated decrements in memory processes. Our research group has published a series of papers reporting a deficit in the acquisition of an operant working memory task, delayed spatial alternation (DSA), following 17β-estradiol treatment to middle-aged ovariectomized (OVX) rats. The current study examined if voluntary exercise could attenuate the 17β-estradiol induced deficits on DSA performance. OVX 12-month old Long- Evans rats were implanted with a Silastic capsule containing 17β-estradiol (10% in cholesterol: low physiological range) or with a blank capsule. A subset of the 17β-estradiol and OVX untreated rats were given free access to a running wheel in their home cage. All rats were tested for 40 sessions on the DSA task. Surprisingly, we found running wheel access to impair initial acquisition of the DSA task in 17β-estradiol treated rats, an effect not seen in OVX untreated rats given running wheel access. This deficit was driven by an increase in perseverative responding on a lever no longer associated with reinforcement. We also report for the first time a 17β-estradiol induced impairment on the DSA task following a long intertrial delay (18-sec), an effect revealed following more extended testing than in our previous studies (15 additional sessions). Overall, running wheel access increased initial error rate on the DSA task in 17β-estradiol treated middle-aged OVX rats, and failed to prevent the 17β-estradiol induced deficits in performance of the operant DSA task in later testing sessions. PMID:24013039

Factors affecting running economy in trained distance runners.

PubMed

Saunders, Philo U; Pyne, David B; Telford, Richard D; Hawley, John A

2004-01-01

Running economy (RE) is typically defined as the energy demand for a given velocity of submaximal running, and is determined by measuring the steady-state consumption of oxygen (VO2) and the respiratory exchange ratio. Taking body mass (BM) into consideration, runners with good RE use less energy and therefore less oxygen than runners with poor RE at the same velocity. There is a strong association between RE and distance running performance, with RE being a better predictor of performance than maximal oxygen uptake (VO2max) in elite runners who have a similar VO2max). RE is traditionally measured by running on a treadmill in standard laboratory conditions, and, although this is not the same as overground running, it gives a good indication of how economical a runner is and how RE changes over time. In order to determine whether changes in RE are real or not, careful standardisation of footwear, time of test and nutritional status are required to limit typical error of measurement. Under controlled conditions, RE is a stable test capable of detecting relatively small changes elicited by training or other interventions. When tracking RE between or within groups it is important to account for BM. As VO2 during submaximal exercise does not, in general, increase linearly with BM, reporting RE with respect to the 0.75 power of BM has been recommended. A number of physiological and biomechanical factors appear to influence RE in highly trained or elite runners. These include metabolic adaptations within the muscle such as increased mitochondria and oxidative enzymes, the ability of the muscles to store and release elastic energy by increasing the stiffness of the muscles, and more efficient mechanics leading to less energy wasted on braking forces and excessive vertical oscillation. Interventions to improve RE are constantly sought after by athletes, coaches and sport scientists. Two interventions that have received recent widespread attention are strength training and altitude training. Strength training allows the muscles to utilise more elastic energy and reduce the amount of energy wasted in braking forces. Altitude exposure enhances discrete metabolic aspects of skeletal muscle, which facilitate more efficient use of oxygen. The importance of RE to successful distance running is well established, and future research should focus on identifying methods to improve RE. Interventions that are easily incorporated into an athlete's training are desirable.

The relationship between energy consumption and economic growth in Malaysia: ARDL bound test approach

NASA Astrophysics Data System (ADS)

Razali, Radzuan; Khan, Habib; Shafie, Afza; Hassan, Abdul Rahman

2016-11-01

The objective of this paper is to examine the short-run and long-run dynamic causal relationship between energy consumption and income per capita both in bivariate and multivariate framework over the period 1971-2014 in the case of Malaysia [1]. The study applies ARDL Bound test procedure for the long run co-integration and Granger causality test for investigation of causal link between the variables. The ARDL bound test confirms the existence of long run co-integration relationship between the variables. The causality test show a feed-back hypothesis between income per capita and energy consumption over the period in the case of Malaysia.

An fMRI study on variation of visuospatial cognitive performance of young male due to highly concentrated oxygen administration

NASA Astrophysics Data System (ADS)

Chung, Soon Cheol; Kim, Ik Hyeon; Tack, Gye Rae; Sohn, Jin Hun

2004-04-01

This study investigated the effects of 30% oxygen administration on the visuospatial cognitive performance using fMRI. Eight college students (right-handed, average age 23.5) were selected as subjects for this study. Oxygen supply equipment which gives 21% and 30% oxygen at a constant rate of 8L/min was developed for this study. To measure the performance of visuospatial cognition, two questionnaires with similar difficulty containing 20 questions each were also developed. Experiment was designed as two runs: run for visuospatial cognition test with normal air (21% of oxygen) and run for visuospatial cognition test with highly concentrated air (30% of oxygen). Run consists of 4 blocks and each block has 8 control problems and 5 visuospatial problems. Functional brain images were taken from 3T MRI using single-shot EPI method. Activities of neural network due to performing visuospatial cognition test were identified using subtraction procedure, and activation areas while performing visuospatial cognition test were extracted using double subtraction procedure. Activities were observed at occipital lobe, parietal lobe, and frontal lobe when performing visuospatial cognition test following both 21% and 30% oxygen administration. But in case of only 30% oxygen administration there were more activities at left precuneus, left cuneus, right postcentral gyrus, bilateral middle frontal gyri, right inferior frontal gyrus, left superior frontal gyrus, bilateral uvula, bilateral pyramis, and nodule compared with 21% oxygen administration. From results of visuospatial cognition test, accuracy rate increased in case of 30% oxygen administration. Thus it could be concluded that highly concentrated oxygen administration has positive effects on the visuospatial cognitive performance.

A novel mouse running wheel that senses individual limb forces: biomechanical validation and in vivo testing

PubMed Central

Roach, Grahm C.; Edke, Mangesh

2012-01-01

Biomechanical data provide fundamental information about changes in musculoskeletal function during development, adaptation, and disease. To facilitate the study of mouse locomotor biomechanics, we modified a standard mouse running wheel to include a force-sensitive rung capable of measuring the normal and tangential forces applied by individual paws. Force data were collected throughout the night using an automated threshold trigger algorithm that synchronized force data with wheel-angle data and a high-speed infrared video file. During the first night of wheel running, mice reached consistent running speeds within the first 40 force events, indicating a rapid habituation to wheel running, given that mice generated >2,000 force-event files/night. Average running speeds and peak normal and tangential forces were consistent throughout the first four nights of running, indicating that one night of running is sufficient to characterize the locomotor biomechanics of healthy mice. Twelve weeks of wheel running significantly increased spontaneous wheel-running speeds (16 vs. 37 m/min), lowered duty factors (ratio of foot-ground contact time to stride time; 0.71 vs. 0.58), and raised hindlimb peak normal forces (93 vs. 115% body wt) compared with inexperienced mice. Peak normal hindlimb-force magnitudes were the primary force component, which were nearly tenfold greater than peak tangential forces. Peak normal hindlimb forces exceed the vertical forces generated during overground running (50-60% body wt), suggesting that wheel running shifts weight support toward the hindlimbs. This force-instrumented running-wheel system provides a comprehensive, noninvasive screening method for monitoring gait biomechanics in mice during spontaneous locomotion. PMID:22723628

14 CFR 29.923 - Rotor drive system and control mechanism tests.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; and (ii) Absorbed by the rotors to be approved for the rotorcraft. (b) Endurance tests; takeoff run. The takeoff run must be conducted as follows: (1) Except as prescribed in paragraphs (b)(2) and (b)(3) of this section, the takeoff torque run must consist of 1 hour of alternate runs of 5 minutes at...

14 CFR 29.923 - Rotor drive system and control mechanism tests.

Code of Federal Regulations, 2011 CFR

2011-01-01

...; and (ii) Absorbed by the rotors to be approved for the rotorcraft. (b) Endurance tests; takeoff run. The takeoff run must be conducted as follows: (1) Except as prescribed in paragraphs (b)(2) and (b)(3) of this section, the takeoff torque run must consist of 1 hour of alternate runs of 5 minutes at...

14 CFR 29.923 - Rotor drive system and control mechanism tests.

Code of Federal Regulations, 2012 CFR

2012-01-01

...; and (ii) Absorbed by the rotors to be approved for the rotorcraft. (b) Endurance tests; takeoff run. The takeoff run must be conducted as follows: (1) Except as prescribed in paragraphs (b)(2) and (b)(3) of this section, the takeoff torque run must consist of 1 hour of alternate runs of 5 minutes at...

14 CFR 29.923 - Rotor drive system and control mechanism tests.

Code of Federal Regulations, 2013 CFR

2013-01-01

...; and (ii) Absorbed by the rotors to be approved for the rotorcraft. (b) Endurance tests; takeoff run. The takeoff run must be conducted as follows: (1) Except as prescribed in paragraphs (b)(2) and (b)(3) of this section, the takeoff torque run must consist of 1 hour of alternate runs of 5 minutes at...

14 CFR 29.923 - Rotor drive system and control mechanism tests.

Code of Federal Regulations, 2014 CFR

2014-01-01

...; and (ii) Absorbed by the rotors to be approved for the rotorcraft. (b) Endurance tests; takeoff run. The takeoff run must be conducted as follows: (1) Except as prescribed in paragraphs (b)(2) and (b)(3) of this section, the takeoff torque run must consist of 1 hour of alternate runs of 5 minutes at...

Short-Term Effects of Rolling Massage on Energy Cost of Running and Power of the Lower Limbs.

PubMed

Giovanelli, Nicola; Vaccari, Filippo; Floreani, Mirco; Rejc, Enrico; Copetti, Jasmine; Garra, Marco; Biasutti, Lea; Lazzer, Stefano

2018-05-10

Self-myofascial release (SMFR) is a type of self-massage that is becoming popular among athletes. However, SMFR effects on running performance have not been investigated yet. The aim of the present study was to evaluate the effects of SMFR on cost of running (Cr). In addition, we evaluated the effects of SMFR on lower limbs muscle power. The measurement of Cr and lower limb muscle power during squat jump (SJ) and counter movement jump (CMJ) were performed before (PRE), immediately after (POST) and 3hours after (POST 3h) a SMFR protocol (experimental condition). In the "control condition" testing session, the same measurements were performed without undergoing the SMFR protocol. Experimental and control conditions were tested in a randomized order. Cr at POST trended to increase as compared to PRE (+6.2±8.3%, p=0.052), while at POST 3h Cr was restored to PRE values (+0.28±9.5%, p=0.950). In the experimental condition, no significant "Time" effect was observed for maximal power exerted during SJ. On the other hand, maximal power exerted during CMJ at POST and POST 3h was significantly higher than that observed at PRE (+7.9±6.3%, p=0.002; and +10.0±8.7%, p=0.004, respectively). The rate of force development measured during CMJ also increased after SMFR, reaching statistical significance at 200 ms from force onset at POST 3h (+38.9%, p=0.024). an acute use of foam roller for SMFR performed immediately prior to running may negatively affect the endurance running performance, while its use should be added before explosive motor performances that include stretch-shortening cycles.

Effects of Step Rate Manipulation on Joint Mechanics during Running

PubMed Central

Heiderscheit, Bryan C.; Chumanov, Elizabeth S.; Michalski, Max P.; Wille, Christa M.; Ryan, Michael B.

2010-01-01

Purpose The objective of this study was to characterize the biomechanical effects of step rate modification during running on the hip, knee and ankle joints, so as to evaluate a potential strategy to reduce lower extremity loading and risk for injury. Methods Three-dimensional kinematics and kinetics were recorded from 45 healthy recreational runners during treadmill running at constant speed under various step rate conditions (preferred, ± 5% and ± 10%). We tested our primary hypothesis that a reduction in energy absorption by the lower extremity joints during the loading response would occur, primarily at the knee, when step rate was increased. Results Less mechanical energy was absorbed at the knee (p<0.01) during the +5% and +10% step rate conditions, while the hip (p<0.01) absorbed less energy during the +10% condition only. All joints displayed substantially (p<0.01) more energy absorption when preferred step rate was reduced by 10. Step length (p<0.01), center of mass vertical excursion (p<0.01), breaking impulse (p<0.01) and peak knee flexion angle (p<0.01) were observed to decrease with increasing step rate. When step rate was increased 10% above preferred, peak hip adduction angle (p<0.01), as well as peak hip adduction (p<0.01) and internal rotation (p<0.01) moments, were found to decrease. Conclusion We conclude that subtle increases in step rate can substantially reduce the loading to the hip and knee joints during running and may prove beneficial in the prevention and treatment of common running-related injuries. PMID:20581720

Running economy and energy cost of running with backpacks.

PubMed

Scheer, Volker; Cramer, Leoni; Heitkamp, Hans-Christian

2018-05-02

Running is a popular recreational activity and additional weight is often carried in backpacks on longer runs. Our aim was to examine running economy and other physiological parameters while running with a 1kg and 3 kg backpack at different submaximal running velocities. 10 male recreational runners (age 25 ± 4.2 years, VO2peak 60.5 ± 3.1 ml·kg-1·min-1) performed runs on a motorized treadmill of 5 minutes durations at three different submaximal speeds of 70, 80 and 90% of anaerobic lactate threshold (LT) without additional weight, and carrying a 1kg and 3 kg backpack. Oxygen consumption, heart rate, lactate and RPE were measured and analysed. Oxygen consumption, energy cost of running and heart rate increased significantly while running with a backpack weighing 3kg compared to running without additional weight at 80% of speed at lactate threshold (sLT) (p=0.026, p=0.009 and p=0.003) and at 90% sLT (p<0.001, p=0.001 and p=0.001). Running with a 1kg backpack showed a significant increase in heart rate at 80% sLT (p=0.008) and a significant increase in oxygen consumption and heart rate at 90% sLT (p=0.045 and p=0.007) compared to running without additional weight. While running at 70% sLT running economy and cardiovascular effort increased with weighted backpack running compared to running without additional weight, however these increases did not reach statistical significance. Running economy deteriorates and cardiovascular effort increases while running with additional backpack weight especially at higher submaximal running speeds. Backpack weight should therefore be kept to a minimum.

Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach.

PubMed

Zhai, Shiyan; Song, Genxin; Qin, Yaochen; Ye, Xinyue; Lee, Jay

2017-01-01

This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a long-run relationship among climate change, technical progress, and the wheat yield per unit area. In the long run, agricultural machinery and fertilizer use both had significantly positive impacts on the per unit area wheat yield. A 1% increase in the aggregate quantity of fertilizer use increased the wheat yield by 0.19%. Additionally, a 1% increase in machine use increased the wheat yield by 0.21%. In contrast, precipitation during the wheat growth period (from emergence to maturity, consisting of the period from last October to June) led to a decrease in the wheat yield per unit area. In the short run, the coefficient of the aggregate quantity of fertilizer used was negative. Land size had a significantly positive impact on the per unit area wheat yield in the short run. There was no significant short-run or long-run impact of temperature on the wheat yield per unit area in Henan Province. The results of our analysis suggest that climate change had a weak impact on the wheat yield, while technical progress played an important role in increasing the wheat yield per unit area. The results of this study have implications for national and local agriculture policies under climate change. To design well-targeted agriculture adaptation policies for the future and to reduce the adverse effects of climate change on the wheat yield, climate change and technical progress factors should be considered simultaneously. In addition, adaptive measures associated with technical progress should be given more attention.

Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach

PubMed Central

Qin, Yaochen; Lee, Jay

2017-01-01

This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a long-run relationship among climate change, technical progress, and the wheat yield per unit area. In the long run, agricultural machinery and fertilizer use both had significantly positive impacts on the per unit area wheat yield. A 1% increase in the aggregate quantity of fertilizer use increased the wheat yield by 0.19%. Additionally, a 1% increase in machine use increased the wheat yield by 0.21%. In contrast, precipitation during the wheat growth period (from emergence to maturity, consisting of the period from last October to June) led to a decrease in the wheat yield per unit area. In the short run, the coefficient of the aggregate quantity of fertilizer used was negative. Land size had a significantly positive impact on the per unit area wheat yield in the short run. There was no significant short-run or long-run impact of temperature on the wheat yield per unit area in Henan Province. The results of our analysis suggest that climate change had a weak impact on the wheat yield, while technical progress played an important role in increasing the wheat yield per unit area. The results of this study have implications for national and local agriculture policies under climate change. To design well-targeted agriculture adaptation policies for the future and to reduce the adverse effects of climate change on the wheat yield, climate change and technical progress factors should be considered simultaneously. In addition, adaptive measures associated with technical progress should be given more attention. PMID:28950027

Exercise protects myelinated fibers of white matter in a rat model of depression.

PubMed

Xiao, Qian; Wang, Feifei; Luo, Yanmin; Chen, Linmu; Chao, Fenglei; Tan, Chuanxue; Gao, Yuan; Huang, Chunxia; Zhang, Lei; Liang, Xin; Tang, Jing; Qi, Yingqing; Jiang, Lin; Zhang, Yi; Zhou, Chunni; Tang, Yong

2018-02-15

The antidepressive effects of exercise have been a focus of research and are hypothesized to remodel the brain networks constructed by myelinated fibers. However, whether the antidepressant effects of exercise are dependent on changes in white matter myelination are unknown. Therefore, we chose chronic unpredictable stress (CUS) as a model of depression and designed an experiment. After a 4-week CUS period, 40 animals were tested using the sucrose preference test (SPT) and the open field test (OFT). The depressed rats then underwent 4-week running exercise. Next, electron microscopy and unbiased stereological methods were used to investigate white matter changes in the rats. After the 4-week CUS stimulation, body weight, sucrose preference and scores on the OFT were significantly lower in the depression rats than in the unstressed rats (p < .05). After undergoing a 4-week running exercise, the depression rats showed a significantly greater sucrose preference than the depression control rats without running exercise (p < .05). Furthermore, the white matter parameters of the depression rats (including the white matter volumes, the length and volumes of myelinated fibers, and the volumes and thickness of the myelin sheaths) were significantly reduced after the CUS period (p < .05). However, these white matter parameters were significantly increased after running exercise (p < .05). The present study is the first to provide evidence that running exercise has positive effects on white matter and the myelinated fibers of white matter in depressed rats, and this evidence might provide an important theoretical basis for the exercise-mediated treatment of depression. © 2017 Wiley Periodicals, Inc.

Fatigue limit and Hysteresis Behavior of Type 304L Stainless Steel in Air and PWR Water, at 150°C and 300°C

NASA Astrophysics Data System (ADS)

Solomon, H. D.; Amzallag, C.; Vallee, A. J.; DeLair, R. E.

This is a study of the 107 cycle fatigue limit of Type 304L Stainless Steel, as measured in fully reversed (R=-1) load-controlled tests, at 150°C and 300°C, in air and PWR water. The staircase method was used to determine the fatigue limit. The tests run here utilized a cycle frequency of 1.818Hz and are compared to other tests from the literature that were run at 30Hz. The fatigue limit measured in the tests run at the high frequency was higher than that measured here. This is explained by measurements of the strain developed during cycling, using the different cycle frequencies. The tests run at the higher frequencies yielded lower strains for a given stress and, as expected, this resulted in higher fatigue limits. Using 107 cycles to define a run-out also led to a lower fatigue limit. These results are important as most previous fatigue limit measurements utilized 106 cycles or less to define a run-out, and when lives as long as 107 cycles are used the tests are generally run at high cycle frequencies, thus leading to higher fatigue limits than those measured here.

Improved running performance in hot humid conditions following whole body precooling.

PubMed

Booth, J; Marino, F; Ward, J J

1997-07-01

On two separate occasions, eight subjects controlled speed to run the greatest distance possible in 30 min in a hot, humid environment (ambient temperature 32 degrees C, relative humidity 60%). For the experimental test (precooling), exercise was preceeded by cold-water immersion. Precooling increased the distance run by 304 +/- 166 m (P < 0.05). Precooling decreased the pre-exercise rectal and mean skin temperature by 0.7 degrees C and 5.9 degrees C, respectively (P < 0.05). Rectal and mean skin temperature were decreased up to 20 and 25 min during exercise, respectively (P < 0.05). Mean body temperature decreased from 36.5 +/- 0.1 degrees C to 33.8 +/- 0.2 degrees C following precooling (P < 0.05) and remained lower throughout exercise (P < 0.01) and at the end of exercise (by 0.8 degrees C; P < 0.05). The rate of heat storage at the end of exercise increased from 113 +/- 45 to 249 +/- 55 W.m-2 (P < 0.005). Precooling lowered the heart rate at rest (13%), 5 (9%), and 10 min (10%) exercise (P < 0.05) and increased the end of exercise blood lactate from 4.9 +/- 0.5 to 7.4 +/- 0.9 mmol.L-1 (P < 0.01). The VO2 at 10 and 20 min of exercise and total body sweating are not different between tests. In conclusion, water immersion precooling increased exercise endurance in hot, humid conditions with an enhanced rate of heat storage and decreased thermoregulatory strain.

The biomechanical differences between barefoot and shod distance running: a systematic review and preliminary meta-analysis.

PubMed

Hall, Jonathan P L; Barton, Christian; Jones, Paul Remy; Morrissey, Dylan

2013-12-01

Distance running continues to experience increased participation in the Western world, although it is associated with high injury rates. Barefoot running has been increasingly proposed as a means to prevent overuse injury due to various biomechanical differences, including reduced joint loading rates and altered kinematics and muscle activity patterns compared to shod running. The aim of this review was to systematically evaluate biomechanical differences between running barefoot and shod, including the quality of available evidence, in order to provide guidance on the phenomenon of barefoot running to the running and sports medicine communities. A comprehensive search of MEDLINE, Web of Knowledge and EMBASE from inception to January 2013 was performed. Trials evaluating injury-free recreational or competitive adults who participate in long-distance running (≥5 km), where a comparison of barefoot and shod running lower-limb kinetics, kinematics and/or electromyography were included. Studies examining sprinting and studies of single-subject design were excluded. Following initial searching, two reviewers identified a shortlist of relevant studies based on title and abstract, with the full text of these studies being tested against the inclusion criteria. References of included studies were examined and citation tracking was performed in Web of Knowledge. Two independent reviewers evaluated the methodological quality of each included study using a modified version of the Downs and Black quality index. Results of the quality assessment were used to identify high- and low-quality studies, data pooling was completed where possible and levels of evidence were determined based on the van Tulder criteria. Eighteen studies were identified, all of low methodological quality. Effect size (ES) calculation was possible for 12 studies. Pooled results indicate moderate evidence that barefoot running is associated with reduced peak ground reaction force (GRF), increased foot and ankle plantarflexion and increased knee flexion at ground contact compared with running in a neutral shoe. Limited evidence indicates barefoot running is associated with reduced impact GRF, reduced peak knee flexion and varus joint moments, and a higher stride frequency compared to a neutral shoe. Very limited to limited evidence also indicates power absorption at the knee is decreased while being increased at the ankle whilst barefoot running. Additionally, the effects of barefoot running on loading rate appear dependent on strike pattern adopted, with a forefoot strike pattern found to reduce loading rate, whilst a rearfoot strike pattern increases loading rate when running barefoot compared to shod. Key methodological weaknesses that must be addressed in future research were identified. Of particular note were absence of investigator blinding, infrequent intervention randomisation, small sample sizes and lack of evaluation following habituation. Two studies could not be retrieved because of publication in a non-English-language journal. Of particular note is that the validity of the body of work is compromised by the lack of evaluation after habituation, or re-training, of previously shod rearfoot-striking runners to barefoot forefoot-striking running styles. There has been a great deal of publicity for barefoot running, and many claims made about its effects and risks. Despite a large amount of biomechanical data available for meta-analysis, clear guidance for clinical practice is limited because of the low methodological quality of the associated studies. Preliminary biomechanical differences identified suggest barefoot running may be associated with positive biomechanical changes in regards to injury prevention, although this may be dependent on strike pattern adopted. Further research employing more robust methodology, which addresses weaknesses highlighted in this review, is needed to confirm current preliminary evidence. Additionally, prospective research would have higher validity were the biomechanical effects of habituating to barefoot running fully examined alongside an evaluation of prevention of repetitive use injury.

An Isolator System for minimally invasive surgery: the new design

PubMed Central

Jansen, Frank-Willem; Dankelman, Jenny

2010-01-01

Background The risk of obtaining a postsurgical infection depends highly on the air quality surrounding the exposed tissue, surgical instruments, and materials. Many isolators for open surgery have been invented to create a contained sterile volume around the exposed tissue. With the use of an isolator, a surgical procedure can be performed outside sterile environments. The goal of this study was to design an Isolator System (IS) for standard laparoscopic instruments while instrument movements are not restricted. Methods The developed IS consists of a sleeve to protect the instrument shaft and tip and a special balloon to protect the incision and trocar tube. A coupling mechanism connected at the sleeve allows instrument changes without contamination of the isolated parts. Smoke tests were performed to show that outside air does not enter the new IS during a simulated laparoscopic procedure. Eight test runs and one baseline run inside a contained volume filled with thick smoke were performed to investigate whether smoke particles entered the Isolator System. Filters were used to identify smoke entering the Isolator System. Results Seven filters showed no trace of smoke particles. In one test run, a part of the IS loosened and a small brown spot was visible. The filter from the baseline run was completely covered with a thick layer of particles, proving the effectiveness of the test. During all test runs, the isolated instrument was successfully locked on and unlocked from the isolated trocar. Instrument movements gave no complications. After removal of the isolated instrument, it took three novices an average of 3.1 (standard deviation (SD), 0.7) seconds to replace it correctly on the isolated trocar. Conclusions The designed IS for laparoscopy can increase sterility in environments where sterility cannot be guaranteed. The current design is developed for laparoscopy, but it can easily be adapted for other fields in minimally invasive surgery. PMID:20108141

Relationship between physical activity, physical fitness and multiple metabolic risk in youths from Muzambinho's study.

PubMed

Barbosa, João Paulo Dos Anjos Souza; Basso, Luciano; Seabra, André; Prista, Antonio; Tani, Go; Maia, José António Ribeiro; Forjaz, Cláudia Lúcia De Moraes

2016-08-01

Negative associations between physical activity (PA), physical fitness and multiple metabolic risk factors (MMRF) in youths from populations with low PA are reported. The persistence of this association in moderately-to highly active populations is not, however, well established. The aim of the present study was to investigate this association in a Brazilian city with high frequency of active youths. We assessed 122 subjects (9.9 ± 1.3 years) from Muzambinho city. Body mass index, waist circumference, glycaemia, cholesterolaemia, systolic and diastolic blood pressures were measured. Maximal handgrip strength and one-mile walk/run test were used. Leisure time PA was assessed by interview. Poisson regression was used in the analysis. The model explained 11% of the total variance. Only relative muscular strength and one-mile walk/run were statistically significant (p < .05). Those who needed more time to cover the one-mile walk/run test had an increased in metabolic risk of 11%, and those with greater strength reduced the risk by about 82%. In conclusion, children and youths from an active population who need less time to cover the one-mile walk/run test or who had greater muscular strength showed a reduced metabolic risk. These results suggest that even in children and youths with high leisure time PA, a greater aerobic fitness and strength might help to further reduce their MMRF.

Exercise Increases Markers of Spermatogenesis in Rats Selectively Bred for Low Running Capacity.

PubMed

Torma, Ferenc; Koltai, Erika; Nagy, Enikő; Ziaaldini, Mohammad Mosaferi; Posa, Aniko; Koch, Lauren G; Britton, Steven L; Boldogh, Istvan; Radak, Zsolt

2014-01-01

The oxidative stress effect of exercise training on testis function is under debate. In the present study we used a unique rat model system developed by artificial selection for low and high intrinsic running capacity (LCR and HCR, respectively) to evaluate the effects of exercise training on apoptosis and spermatogenesis in testis. Twenty-four 13-month-old male rats were assigned to four groups: control LCR (LCR-C), trained LCR (LCR-T), control HCR (HCR-C), and trained HCR (HCR-T). Ten key proteins connecting aerobic exercise capacity and general testes function were assessed, including those that are vital for mitochondrial biogenesis. The VO2 max of LCR-C group was about 30% lower than that of HCR-C rats, and the SIRT1 levels were also significantly lower than HCR-C. Twelve weeks of training significantly increased maximal oxygen consumption in LCR by nearly 40% whereas HCR remained unchanged. LCR-T had significantly higher levels of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1α), decreased levels of reactive oxygen species and increased acetylated p53 compared to LCR-C, while training produced no significant changes for these measures in HCR rats. BAX and Blc-2 were not different among all four groups. The levels of outer dense fibers -1 (Odf-1), a marker of spermatogenesis, increased in LCR-T rats, but decreased in HCR-TR rats. Moreover, exercise training increased the levels of lactate dehydrogenase C (LDHC) only in LCR rats. These data suggest that rats with low inborn exercise capacity can increase whole body oxygen consumption and running exercise capacity with endurance training and, in turn, increase spermatogenesis function via reduction in ROS and heightened activity of p53 in testes.

Reliability and validity of pressure and temporal parameters recorded using a pressure-sensitive insole during running.

PubMed

Mann, Robert; Malisoux, Laurent; Brunner, Roman; Gette, Paul; Urhausen, Axel; Statham, Andrew; Meijer, Kenneth; Theisen, Daniel

2014-01-01

Running biomechanics has received increasing interest in recent literature on running-related injuries, calling for new, portable methods for large-scale measurements. Our aims were to define running strike pattern based on output of a new pressure-sensitive measurement device, the Runalyser, and to test its validity regarding temporal parameters describing running gait. Furthermore, reliability of the Runalyser measurements was evaluated, as well as its ability to discriminate different running styles. Thirty-one healthy participants (30.3 ± 7.4 years, 1.78 ± 0.10 m and 74.1 ± 12.1 kg) were involved in the different study parts. Eleven participants were instructed to use a rearfoot (RFS), midfoot (MFS) and forefoot (FFS) strike pattern while running on a treadmill. Strike pattern was subsequently defined using a linear regression (R(2)=0.89) between foot strike angle, as determined by motion analysis (1000 Hz), and strike index (SI, point of contact on the foot sole, as a percentage of foot sole length), as measured by the Runalyser. MFS was defined by the 95% confidence interval of the intercept (SI=43.9-49.1%). High agreement (overall mean difference 1.2%) was found between stance time, flight time, stride time and duty factor as determined by the Runalyser and a force-measuring treadmill (n=16 participants). Measurements of the two devices were highly correlated (R ≥ 0.80) and not significantly different. Test-retest intra-class correlation coefficients for all parameters were ≥ 0.94 (n=14 participants). Significant differences (p<0.05) between FFS, RFS and habitual running were detected regarding SI, stance time and stride time (n=24 participants). The Runalyser is suitable for, and easily applicable in large-scale studies on running biomechanics. Copyright © 2013 Elsevier B.V. All rights reserved.

Separating the effects of shelter from additional cage enhancements for group-housed BALB/cJ mice.

PubMed

Swetter, Brentt J; Karpiak, Christie P; Cannon, J Timothy

2011-05-20

Enrichment studies with rodents have demonstrated that cage enhancements can improve animal welfare and performance on common behavioral measures, but few studies have compared more than one type of enrichment or controlled for confounds, and some have revealed undesirable effects including increased aggression. We compared effects on male (n=51) and female (n=52) BALB/cJ mice of three common additions to a standard home cage: shelter, shelter+running wheel, and shelter+novel objects. Mice in all conditions lived in standard sized cages with 3-4 mice per cage. Males evidenced significant condition effects. Shelter increased longevity and maintained low levels of aggression. Adding a running wheel increased aggression over shelter alone, changed behavior in the elevated plus (EP) and open field (OF), and maintained the improved longevity seen in all shelter conditions. Novel objects impacted behavioral measures compared to the standard condition. An Igloo shelter without running wheel creates a very different home cage environment than the same shelter with the running wheel attached. Shelter, with positive impact on animal welfare, minimal effects on some common behavioral measures, and some positive effects on test variance, warrants consideration for routine inclusion with group-housed BALB/cJ males. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

40 CFR Appendix B to Part 61 - Test Methods

Code of Federal Regulations, 2010 CFR

2010-07-01

... below 28 liters/min (1.0 cfm). 8.2.2Perform test runs such that samples are obtained over a period or... cyclic operations, run sufficient tests for the accurate determination of the emissions that occur over... indicated by reddening (liberation of free iodine) in the first impinger. In these cases, the sample run may...

MICROSTRUCTURAL AND MECHANICAL CHARACTERIZATION OF 2-D AND 3-D SiC/SiNC CERAMIC MATRIX COMPOSITES

DTIC Science & Technology

2018-02-23

48 5.2 Residual Strength of Test Specimens Reaching Run -Out ...........................................48 5.3 Fracture...46 Table 10. Residual Strength Tension Test Results for Creep Rupture Specimens Reaching Run - Out...Residual Strength Tension Test Results for Fatigue Specimens Reaching Run -Out . 49 vii Distribution Statement A. Approved for public release

40 CFR Appendix B to Part 61 - Test Methods

Code of Federal Regulations, 2013 CFR

2013-07-01

... below 28 liters/min (1.0 cfm). 8.2.2Perform test runs such that samples are obtained over a period or... cyclic operations, run sufficient tests for the accurate determination of the emissions that occur over... indicated by reddening (liberation of free iodine) in the first impinger. In these cases, the sample run may...

40 CFR Appendix B to Part 61 - Test Methods

Code of Federal Regulations, 2012 CFR

2012-07-01

... below 28 liters/min (1.0 cfm). 8.2.2Perform test runs such that samples are obtained over a period or... cyclic operations, run sufficient tests for the accurate determination of the emissions that occur over... indicated by reddening (liberation of free iodine) in the first impinger. In these cases, the sample run may...

40 CFR Appendix B to Part 61 - Test Methods

Code of Federal Regulations, 2011 CFR

2011-07-01

... below 28 liters/min (1.0 cfm). 8.2.2Perform test runs such that samples are obtained over a period or... cyclic operations, run sufficient tests for the accurate determination of the emissions that occur over... indicated by reddening (liberation of free iodine) in the first impinger. In these cases, the sample run may...

40 CFR Appendix B to Part 61 - Test Methods

Code of Federal Regulations, 2014 CFR

2014-07-01

... below 28 liters/min (1.0 cfm). 8.2.2Perform test runs such that samples are obtained over a period or... cyclic operations, run sufficient tests for the accurate determination of the emissions that occur over... indicated by reddening (liberation of free iodine) in the first impinger. In these cases, the sample run may...

40 CFR Table 1 to Subpart Cccc of... - Emission Limitations

Code of Federal Regulations, 2011 CFR

2011-07-01

... per dry standard cubic meter 3-run average (1 hour minimum sample time per run) Performance test (Method 29 of appendix A of this part). Carbon monoxide 157 parts per million by dry volume 3-run average (1 hour minimum sample time per run) Performance test (Method 10, 10A, or 10B of appendix A of this...

40 CFR Table 1 to Subpart Cccc of... - Emission Limitations

Code of Federal Regulations, 2010 CFR

2010-07-01

... per dry standard cubic meter 3-run average (1 hour minimum sample time per run) Performance test (Method 29 of appendix A of this part). Carbon monoxide 157 parts per million by dry volume 3-run average (1 hour minimum sample time per run) Performance test (Method 10, 10A, or 10B of appendix A of this...

40 CFR Table 2 to Subpart Dddd of... - Model Rule-Emission Limitations

Code of Federal Regulations, 2010 CFR

2010-07-01

... meter 3-run average (1 hour minimum sample time per run) Performance test (Method 29 of appendix A of this part) Carbon monoxide 157 parts per million by dry volume 3-run average (1 hour minimum sample time per run) Performance test (Method 10, 10A, or 10B, of appendix A of this part) Dioxins/furans...

Criterion-Related Validity of the Distance- and Time-Based Walk/Run Field Tests for Estimating Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis

PubMed Central

Mayorga-Vega, Daniel; Bocanegra-Parrilla, Raúl; Ornelas, Martha; Viciana, Jesús

2016-01-01

Objectives The main purpose of the present meta-analysis was to examine the criterion-related validity of the distance- and time-based walk/run tests for estimating cardiorespiratory fitness among apparently healthy children and adults. Materials and Methods Relevant studies were searched from seven electronic bibliographic databases up to August 2015 and through other sources. The Hunter-Schmidt’s psychometric meta-analysis approach was conducted to estimate the population criterion-related validity of the following walk/run tests: 5,000 m, 3 miles, 2 miles, 3,000 m, 1.5 miles, 1 mile, 1,000 m, ½ mile, 600 m, 600 yd, ¼ mile, 15 min, 12 min, 9 min, and 6 min. Results From the 123 included studies, a total of 200 correlation values were analyzed. The overall results showed that the criterion-related validity of the walk/run tests for estimating maximum oxygen uptake ranged from low to moderate (rp = 0.42–0.79), with the 1.5 mile (rp = 0.79, 0.73–0.85) and 12 min walk/run tests (rp = 0.78, 0.72–0.83) having the higher criterion-related validity for distance- and time-based field tests, respectively. The present meta-analysis also showed that sex, age and maximum oxygen uptake level do not seem to affect the criterion-related validity of the walk/run tests. Conclusions When the evaluation of an individual’s maximum oxygen uptake attained during a laboratory test is not feasible, the 1.5 mile and 12 min walk/run tests represent useful alternatives for estimating cardiorespiratory fitness. As in the assessment with any physical fitness field test, evaluators must be aware that the performance score of the walk/run field tests is simply an estimation and not a direct measure of cardiorespiratory fitness. PMID:26987118

Comparison of physiological and acid-base balance response during uphill, level and downhill running performed at constant velocity.

PubMed

Maciejczyk, Marcin; Więcek, M; Szymura, J; Szyguła, Z

2013-09-01

The purpose of this study was to compare the physiological and the acid-base balance response to running at various slope angles. Ten healthy men 22.3 ± 1.56 years old participated in the study. The study consisted of completing the graded test until exhaustion and three 45-minute runs. For the first 30 minutes, runs were performed with an intensity of approximately 50% VO2max, while in the final 15 minutes the slope angle of treadmill was adjusted (0°; +4.5°; -4.5°), and a fixed velocity of running was maintained. During concentric exercise, a significant increase in the levels of physiological indicators was reported; during eccentric exercise, a significant decrease in the level of the analyzed indicators was observed. Level running did not cause significant changes in the indicators of acid-base balance. The indicators of acid-base balance changed significantly in the case of concentric muscle work (in comparison to level running) and after the eccentric work, significant and beneficial changes were observed in most of the biochemical indicators. The downhill run can be used for a partial regeneration of the body during exercise, because during this kind of effort an improvement of running economy was observed, and this type of effort did not impair the acid-base balance of body.

Treadmill running prevents age-related memory deficit and alters neurotrophic factors and oxidative damage in the hippocampus of Wistar rats.

PubMed

Vanzella, Cláudia; Neves, Juliana Dalibor; Vizuete, Adriana Fernanda; Aristimunha, Dirceu; Kolling, Janaína; Longoni, Aline; Gonçalves, Carlos Alberto Saraiva; Wyse, Angela T S; Netto, Carlos Alexandre

2017-09-15

Clinical and pre-clinical studies indicate that exercise is beneficial to many aspects of brain function especially during aging. The present study investigated the effects of a treadmill running protocol in young (3month-old) and aged (22month-old) male Wistar rats, on: I) cognitive function, as assessed by spatial reference memory in the Morris water maze; II) oxidative stress parameters and the expression of neurotrophic factors BDNF, NT-3, IGF-1 and VEGF in the hippocampus. Animals of both ages were assigned to sedentary (non-exercised) and exercised (20min of daily running sessions, 3 times per week for 4weeks) groups. Cognition was assessed by a reference memory task run in the Morris water maze; twenty four hours after last session of behavioral testing hippocampi were collected for biochemical analysis. Results demonstrate that the moderate treadmill running exercise: I) prevented age-related deficits in reference memory in the Morris water maze; II) prevented the age-related increase of reactive oxygen species levels and lipid peroxidation in the hippocampus; III) caused an increase of BDNF, NT-3 and IGF-1 expression in the hippocampus of aged rats. Taken together, results suggest that both exercise molecular effects, namely the reduction of oxidative stress and the increase of neurotrophic factors expression in the hippocampus, might be related to its positive effect on memory performance in aged rats. Copyright © 2017 Elsevier B.V. All rights reserved.

Physiological effects of bioceramic material: harvard step, resting metabolic rate and treadmill running assessments.

PubMed

Leung, Ting-Kai; Kuo, Chia-Hua; Lee, Chi-Ming; Kan, Nai-Wen; Hou, Chien-Wen

2013-12-31

Previous biomolecular and animal studies have shown that a room-temperature far-infrared-rayemitting ceramic material (bioceramic) demonstrates physical-biological effects, including the normalization of psychologically induced stress-conditioned elevated heart rate in animals. In this clinical study, the Harvard step test, the resting metabolic rate (RMR) assessment and the treadmill running test were conducted to evaluate possible physiological effects of the bioceramic material in human patients. The analysis of heart rate variability (HRV) during the Harvard step test indicated that the bioceramic material significantly increased the high-frequency (HF) power spectrum. In addition, the results of RMR analysis suggest that the bioceramic material reduced oxygen consumption (VO2). Our results demonstrate that the bioceramic material has the tendency to stimulate parasympathetic responses, which may reduce resting energy expenditure and improve cardiorespiratory recovery following exercise.

Spontaneous Entrainment of Running Cadence to Music Tempo.

PubMed

Van Dyck, Edith; Moens, Bart; Buhmann, Jeska; Demey, Michiel; Coorevits, Esther; Dalla Bella, Simone; Leman, Marc

Since accumulating evidence suggests that step rate is strongly associated with running-related injuries, it is important for runners to exercise at an appropriate running cadence. As music tempo has been shown to be capable of impacting exercise performance of repetitive endurance activities, it might also serve as a means to (re)shape running cadence. The aim of this study was to validate the impact of music tempo on running cadence. Sixteen recreational runners ran four laps of 200 m (i.e. 800 m in total); this task was repeated 11 times with a short break in between each four-lap sequence. During the first lap of a sequence, participants ran at a self-paced tempo without musical accompaniment. Running cadence of the first lap was registered, and during the second lap, music with a tempo matching the assessed cadence was played. In the final two laps, the music tempo was either increased/decreased by 3.00, 2.50, 2.00, 1.50, or 1.00 % or was kept stable. This range was chosen since the aim of this study was to test spontaneous entrainment (an average person can distinguish tempo variations of about 4 %). Each participant performed all conditions. Imperceptible shifts in musical tempi in proportion to the runner's self-paced running tempo significantly influenced running cadence ( p  < .001). Contrasts revealed a linear relation between the tempo conditions and adaptation in running cadence ( p  < .001). In addition, a significant effect of condition on the level of entrainment was revealed ( p  < .05), which suggests that maximal effects of music tempo on running cadence can only be obtained up to a certain level of tempo modification. Finally, significantly higher levels of tempo entrainment were found for female participants compared to their male counterparts ( p  < .05). The applicable contribution of these novel findings is that music tempo could serve as an unprompted means to impact running cadence. As increases in step rate may prove beneficial in the prevention and treatment of common running-related injuries, this finding could be especially relevant for treatment purposes, such as exercise prescription and gait retraining. Music tempo can spontaneously impact running cadence.A basin for unsolicited entrainment of running cadence to music tempo was discovered.The effect of music tempo on running cadence proves to be stronger for women than for men.

Progression in Running Intensity or Running Volume and the Development of Specific Injuries in Recreational Runners: Run Clever, a Randomized Trial Using Competing Risks.

PubMed

Ramskov, Daniel; Rasmussen, Sten; Sørensen, Henrik; Parner, Erik Thorlund; Lind, Martin; Nielsen, Rasmus

2018-06-12

Study Design Randomized clinical trial, etiology. Background Training intensity and volume have been proposed to be associated with specific running-related injuries. If such an association exists, secondary preventive measures could be initiated by clinicians based on symptoms of a specific injury diagnosis. Objectives To test the following hypotheses: (i) A running schedule focusing on intensity will increase the risk of sustaining Achilles tendinopathy, gastrocnemius injuries and plantar fasciitis compared with hypothesized volume-related injuries. (ii) A running schedule focusing on running volume will increase the risk of sustaining patellofemoral pain syndrome, iliotibial band syndrome and patellar tendinopathy compared with hypothesized intensity-related injuries. Methods Healthy recreational runners were included in a 24-week follow-up, divided into 8-week preconditioning and 16-week specific focus-training. Participants were randomized to one of two running schedules: Schedule Intensity(Sch-I) or Schedule Volume(Sch-V). Sch-I progressed the amount of high intensity running (≥88% VO2max) each week. Sch-V progressed total weekly running volume. Global positioning system watch or smartphone collected data on running. Running-related injuries were diagnosed based on a clinical examination. Estimates were risk difference (RD) and 95%CI. Results Of 447 runners, a total of 80 sustained an injury (Sch-I n=36; Sch-V n=44). Risk of intensity injuries in Sch-I were: RD 2-weeks =-0.8%[-5.0;3.4]; RD 4-weeks =-0.8%[-6.7;5.1]; RD 8-weeks =-2.0%[-9.2;5.1]; RD 16-weeks =-5.1%[-16.5;6.3]. Risk of volume injuries in Sch-V were: RD 2-weeks =-0.9%[-5.0;3.2]; RD 4-weeks =-2.0%[-7.5;3.5]; RD 8-weeks =-3.2%[-9.1;2.7]; RD 16-weeks =-3.4%[-13.2;6.2]. Conclusion No difference in risk of hypothesized intensity and volume specific running-related injuries exist between running schedules focused on progression in either running intensity or volume. Level of Evidence Etiology, level 1b. J Orthop Sports Phys Ther, Epub 12 Jun 2018. doi:10.2519/jospt.2018.8062.

Chandra X-ray Center Science Data Systems Regression Testing of CIAO

NASA Astrophysics Data System (ADS)

Lee, N. P.; Karovska, M.; Galle, E. C.; Bonaventura, N. R.

2011-07-01

The Chandra Interactive Analysis of Observations (CIAO) is a software system developed for the analysis of Chandra X-ray Observatory observations. An important component of a successful CIAO release is the repeated testing of the tools across various platforms to ensure consistent and scientifically valid results. We describe the procedures of the scientific regression testing of CIAO and the enhancements made to the testing system to increase the efficiency of run time and result validation.

Enhancing physical performance in elite junior tennis players with a caffeinated energy drink.

PubMed

Gallo-Salazar, César; Areces, Francisco; Abián-Vicén, Javier; Lara, Beatriz; Salinero, Juan José; Gonzalez-Millán, Cristina; Portillo, Javier; Muñoz, Victor; Juarez, Daniel; Del Coso, Juan

2015-04-01

The aim of this study was to investigate the effectiveness of a caffeinated energy drink to enhance physical performance in elite junior tennis players. In 2 different sessions separated by 1 wk, 14 young (16 ± 1 y) elite-level tennis players ingested 3 mg caffeine per kg body mass in the form of an energy drink or the same drink without caffeine (placebo). After 60 min, participants performed a handgrip-strength test, a maximal-velocity serving test, and an 8 × 15-m sprint test and then played a simulated singles match (best of 3 sets). Instantaneous running speed during the matches was assessed using global positioning (GPS) devices. Furthermore, the matches were videotaped and notated afterward. In comparison with the placebo drink, the ingestion of the caffeinated energy drink increased handgrip force by ~4.2% ± 7.2% (P = .03) in both hands, the running pace at high intensity (46.7 ± 28.5 vs 63.3 ± 27.7 m/h, P = .02), and the number of sprints (12.1 ± 1.7 vs 13.2 ± 1.7, P = .05) during the simulated match. There was a tendency for increased maximal running velocity during the sprint test (22.3 ± 2.0 vs 22.9 ± 2.1 km/h, P = .07) and higher percentage of points won on service with the caffeinated energy drink (49.7% ± 9.8% vs 56.4% ± 10.0%, P = .07) in comparison with the placebo drink. The energy drink did not improve ball velocity during the serving test (42.6 ± 4.8 vs 42.7 ± 5.0 m/s, P = .49). The preexercise ingestion of caffeinated energy drinks was effective to enhance some aspects of physical performance of elite junior tennis players.

RP-1 Thermal Stability and Copper Based Materials Compatibility Study

NASA Technical Reports Server (NTRS)

Stiegemeier, B. R.; Meyer, M. L.; Driscoll, E.

2005-01-01

A series of electrically heated tube tests was performed at the NASA Glenn Research Center s Heated Tube Facility to investigate the effect that sulfur content, test duration, and tube material play in the overall thermal stability and materials compatibility characteristics of RP-1. Scanning-electron microscopic (SEM) analysis in conjunction with energy dispersive spectroscopy (EDS) were used to characterize the condition of the tube inner wall surface and any carbon deposition or corrosion formed during these runs. Results of the parametric study indicate that tests with standard RP-1 (total sulfur -23 ppm) and pure copper tubing are characterized by a depostion/deposit shedding process producing local wall temperature swings as high as 500 F. The effect of this shedding is to keep total carbon deposition levels relatively constant for run times from 20 minutes up to 5 hours, though increasing tube pressure drops were observed in all runs. Reduction in the total sulfur content of the fuel from 23 ppm to less than 0.1 ppm resulted in the elimination of deposit shedding, local wall temperature variation, and the tube pressure drop increases that were observed in standard sulfur level RP-1 tests. The copper alloy GRCop-84, a copper alloy developed specifically for high heat flux applications, was found to exhibit higher carbon deposition levels compared to identical tests performed in pure copper tubes. Results of the study are consistent with previously published heated tube data which indicates that small changes in fuel total sulfur content can lead to significant differences in the thermal stability of kerosene type fuels and their compatibility with copper based materials. In conjunction with the existing thermal stability database, these findings give insight into the feasibility of cooling a long life, high performance, high-pressure liquid rocket combustor and nozzle with RP-1.

Measuring joint kinematics of treadmill walking and running: Comparison between an inertial sensor based system and a camera-based system.

PubMed

Nüesch, Corina; Roos, Elena; Pagenstert, Geert; Mündermann, Annegret

2017-05-24

Inertial sensor systems are becoming increasingly popular for gait analysis because their use is simple and time efficient. This study aimed to compare joint kinematics measured by the inertial sensor system RehaGait® with those of an optoelectronic system (Vicon®) for treadmill walking and running. Additionally, the test re-test repeatability of kinematic waveforms and discrete parameters for the RehaGait® was investigated. Twenty healthy runners participated in this study. Inertial sensors and reflective markers (PlugIn Gait) were attached according to respective guidelines. The two systems were started manually at the same time. Twenty consecutive strides for walking and running were recorded and each software calculated sagittal plane ankle, knee and hip kinematics. Measurements were repeated after 20min. Ensemble means were analyzed calculating coefficients of multiple correlation for waveforms and root mean square errors (RMSE) for waveforms and discrete parameters. After correcting the offset between waveforms, the two systems/models showed good agreement with coefficients of multiple correlation above 0.950 for walking and running. RMSE of the waveforms were below 5° for walking and below 8° for running. RMSE for ranges of motion were between 4° and 9° for walking and running. Repeatability analysis of waveforms showed very good to excellent coefficients of multiple correlation (>0.937) and RMSE of 3° for walking and 3-7° for running. These results indicate that in healthy subjects sagittal plane joint kinematics measured with the RehaGait® are comparable to those using a Vicon® system/model and that the measured kinematics have a good repeatability, especially for walking. Copyright © 2017 Elsevier Ltd. All rights reserved.

On the causal links between health indicator, output, combustible renewables and waste consumption, rail transport, and CO2 emissions: the case of Tunisia.

PubMed

Ben Jebli, Mehdi

2016-08-01

This study employs the autoregressive distributed lag (ARDL) approach and Granger causality test to investigate the short- and long-run relationships between health indicator, real GDP, combustible renewables and waste consumption, rail transport, and carbon dioxide (CO2) emissions for the case of Tunisia, spanning the period of 1990-2011. The empirical findings suggest that the Fisher statistic of the Wald test confirm the existence of a long-run relationship between the variables. Moreover, the long-run estimated elasticities of the ARDL model provide that output and combustible renewables and waste consumption have a positive and statistically significant impact on health situation, while CO2 emissions and rail transport both contribute to the decrease of health indicator. Granger causality results affirm that, in the short-run, there is a unidirectional causality running from real GDP to health, a unidirectional causality from health to combustible renewables and waste consumption, and a unidirectional causality from all variables to CO2 emissions. In the long-run, all the computed error correction terms are significant and confirm the existence of long-run association among the variables. Our recommendations for the Tunisian policymakers are as follows: (i) exploiting wastes and renewable fuels can be a good strategy to eliminate pollution caused by emissions and subsequently improve health quality, (ii) the use of renewable energy as a main source for national rail transport is an effective strategy for public health, (iii) renewable energy investment projects are beneficial plans for the country as this contributes to the growth of its own economy and reduce energy dependence, and (iii) more renewable energy consumption leads not only to decrease pollution but also to stimulate health situation because of the increase of doctors and nurses numbers.

Anaerobic fitness tests: what are we measuring?

PubMed

Van Praagh, Emmanuel

2007-01-01

Anaerobic fitness, during growth and development, has not received the same attention from researchers as aerobic fitness. This is surprising given the level of anaerobic energy used daily during childhood and adolescence. During physical activity and sport, the child is spontaneously more attracted to short-burst movements than to long-term activities. It is, however, well known that in anaerobic activities such as sprint cycling, sprint running or sprint swimming, the child's performance is distinctly poorer than that of the adult. This partly reflects the child's lesser ability to generate mechanical energy from chemical energy sources during short-term high-intensity work or exercise. Direct measurements of the rate or capacity of anaerobic pathways for energy turnover presents several ethical and methodological difficulties. Therefore, rather than measure energy supply, pediatric exercise scientists have concentrated on measuring short-term power output by means of standardized protocol tests such as short-term cycling power tests, running tests or vertical jump tests. There is, however, no perfect test and, therefore, it is important to acknowledge the benefits and limitations of each testing method. Mass-related short-term power output was shown to increase dramatically during growth and development, whereas the corresponding increase in peak blood lactate was considerably lower. This suggests that the observed difference between children and adolescents during short-term power output testing may be related to neuromuscular factors, hormonal factors and improved motor coordination.

Testing for purchasing power parity in the long-run for ASEAN-5

NASA Astrophysics Data System (ADS)

Choji, Niri Martha; Sek, Siok Kun

2017-04-01

For more than a decade, there has been a substantial interest in testing for the validity of the purchasing power parity (PPP) hypothesis empirically. This paper performs a test on revealing a long-run relative Purchasing Power Parity for a group of ASEAN-5 countries for the period of 1996-2016 using monthly data. For this purpose, we used the Pedroni co-integration method to test for the long-run hypothesis of purchasing power parity. We first tested for the stationarity of the variables and found that the variables are non-stationary at levels but stationary at first difference. Results of the Pedroni test rejected the null hypothesis of no co-integration meaning that we have enough evidence to support PPP in the long-run for the ASEAN-5 countries over the period of 1996-2016. In other words, the rejection of null hypothesis implies a long-run relation between nominal exchange rates and relative prices.

Running shoes increase achilles tendon load in walking: an acoustic propagation study.

PubMed

Wearing, Scott C; Reed, Lloyd; Hooper, Sue L; Bartold, Simon; Smeathers, James E; Brauner, Torsten

2014-08-01

Footwear remains a prime candidate for the prevention and rehabilitation of Achilles tendinopathy because it is thought to decrease tension in the tendon through elevation of the heel. However, evidence for this effect is equivocal. This study used an acoustic transmission technique to investigate the effect of running shoes on Achilles tendon loading during barefoot and shod walking. Acoustic velocity was measured in the Achilles tendon of 12 recreationally active males (age, 31 ± 9 yr; height, 1.78 ± 0.06 m; weight, 81.0 ± 16.9 kg) during barefoot and shod walking at matched self-selected speed (3.4 ± 0.7 km·h). Standard running shoes incorporating a 10-mm heel offset were used. Vertical ground reaction force and spatiotemporal parameters were determined with an instrumented treadmill. Axial acoustic velocity in the Achilles tendon was measured using a custom-built ultrasonic device. All data were acquired at a rate of 100 Hz during 10 s of steady-state walking. Statistical comparisons between barefoot and shod conditions were made using paired t-tests and repeated-measure ANOVA. Acoustic velocity in the Achilles tendon was highly reproducible and was typified by two maxima (P1, P2) and minima (M1, M2) during walking. Footwear resulted in a significant increase in step length, stance duration, and peak vertical ground reaction force compared with barefoot walking. Peak acoustic velocity in the Achilles tendon (P1, P2) was significantly higher with running shoes. Peak acoustic velocity in the Achilles tendon was higher with footwear, suggesting that standard running shoes with a 10-mm heel offset increase tensile load in the Achilles tendon. Although further research is required, these findings question the therapeutic role of standard running shoes in Achilles tendinopathy.

Speed and agility of 12- and 14-year-old elite male basketball players.

PubMed

Jakovljevic, Sasa T; Karalejic, Milivoje S; Pajic, Zoran B; Macura, Marija M; Erculj, Frane F

2012-09-01

The aims of this study were (a) to identify and compare the speed and agility of 12- and 14-year-old elite male basketball players and (b) to investigate relations between speed and agility for both age groups of basketball players, to help coaches to improve their work. Sixty-four players aged 12 (M = 11.98 years, SD = 0.311) and 54 players aged 14 (M = 14.092 years, SD = 0.275) were tested. Three agility tests: agility t-test, zigzag agility drill, and agility run 4 × 15 m and 3 speed tests: 20-m run, 30-m run, and 50-m run were applied. Fourteen-year-old players achieved significantly better results in all speed and agility tests compared with 12-year-old players. The correlation coefficient (r = 0.81, p = 0.001) showed that 12-year-old players have the same ability in the 30- and 50-m runs. The other correlation coefficient (r = 0.59, p = 0.001) indicated that 20- and 30-m runs had inherently different qualities. The correlation coefficients between agility tests were <0.71, and therefore, each test in this group represents a specific task. In 14-year-old players, the correlation coefficients between the speed test results were <0.71. In contrast, the correlation coefficients between the agility tests were >0.71, which means that all the 3 tests represent the same quality. During the speed training of 12-year-old players, it is advisable to focus on shorter running distances, up to 30 m. During the agility training of the same players, it is useful to apply exercises with various complexities. In speed training of the 14-year-old players, the 30- and 50-m runs should be applied, and agility training should include more specific basketball movements and activities.

Experimental evaluation of oxygen-enriched air and emulsified fuels in a six-cylinder diesel engine

NASA Astrophysics Data System (ADS)

Sekar, R. R.; Marr, W. W.; Cole, R. L.; Marciniak, T. J.; Longman, D. E.

1993-01-01

The objectives of this investigation are to (1) determine the technical feasibility of using oxygen-enriched air to increase the efficiency of and reduce emissions from diesel engines, (2) examine the effects of water-emulsified fuel on the formation of nitrogen oxides in oxygen-enriched combustion, and (3) investigate the use of lower-grade fuels in high-speed diesel engines by emulsifying the fuel with water. These tests, completed on a Caterpillar model 3406B, six-cylinder engine are a scale-up from previous, single-cylinder-engine tests. The engine was tested with (1) intake-air oxygen levels up to 30%, (2) water content up to 20% of the fuel, (3) three fuel-injection timings, and (4) three fuel-flow rates (power levels). The Taguchi technique for experimental design was used to minimize the number of experimental points in the test matrix. Four separate test matrices were run to cover two different fuel-flow-rate strategies and two different fuels (No. 2 diesel and No. 6 diesel). A liquid-oxygen tank located outside the test cell supplied the oxygen for the tests. The only modification of the engine was installation of a pressure transducer in one cylinder. All tests were run at 1800 rpm, which corresponds to the synchronous speed of a 60-Hz generator. Test results show that oxygen enrichment results in power increases of 50% or more while significantly decreasing the levels of smoke and particulates emitted. The increase in power was accompanied by a small increase in thermal efficiency. Maximum engine power was limited by the test-cell dynamometer capacity and the capacity of the fuel-injection pump. Oxygen enrichment increases nitrogen-oxide emissions significantly. No adverse effects of oxygen enrichment on the turbocharger were observed. The engine operated successfully with No. 6 fuel, but it operated at a lower thermal efficiency and emitted more smoke and particulates than with No. 2 fuel.

14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Gross dimensions of aircraft and location of engines. (iii) Aircraft gross weight for each test run. (iv... arithmetic average of the corrected noise measurements for all valid test runs at the takeoff, level flyovers... limit for all valid test runs under section H36.111(d) of this appendix applies separately to the EPNdB...

14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Gross dimensions of aircraft and location of engines. (iii) Aircraft gross weight for each test run. (iv... arithmetic average of the corrected noise measurements for all valid test runs at the takeoff, level flyovers... limit for all valid test runs under section H36.111(d) of this appendix applies separately to the EPNdB...

14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Gross dimensions of aircraft and location of engines. (iii) Aircraft gross weight for each test run. (iv... arithmetic average of the corrected noise measurements for all valid test runs at the takeoff, level flyovers... limit for all valid test runs under section H36.111(d) of this appendix applies separately to the EPNdB...

14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Gross dimensions of aircraft and location of engines. (iii) Aircraft gross weight for each test run. (iv... arithmetic average of the corrected noise measurements for all valid test runs at the takeoff, level flyovers... limit for all valid test runs under section H36.111(d) of this appendix applies separately to the EPNdB...

A Modified T-Test for Football Referees to Test Agility, Quickness and Sprint Performances

ERIC Educational Resources Information Center

Muniroglu, S.; Subak, E.

2018-01-01

The football referees perform many actions as jogging, running, sprinting, side steps and backward steps during a football match. Further, the football referees change match activities every 5-6 seconds. Many tests are being conducted to determine the physical levels and competences of football referees like 50 m running, 200 m running, 12 minutes…

Effects of Run-Up Velocity on Performance, Kinematics, and Energy Exchanges in The Pole Vault

PubMed Central

Linthorne, Nicholas P.; Weetman, A. H. Gemma

2012-01-01

This study examined the effect of run-up velocity on the peak height achieved by the athlete in the pole vault and on the corresponding changes in the athlete's kinematics and energy exchanges. Seventeen jumps by an experienced male pole vaulter were video recorded in the sagittal plane and a wide range of run-up velocities (4.5-8.5 m/s) was obtained by setting the length of the athlete's run-up (2-16 steps). A selection of performance variables, kinematic variables, energy variables, and pole variables were calculated from the digitized video data. We found that the athlete's peak height increased linearly at a rate of 0.54 m per 1 m/s increase in run-up velocity and this increase was achieved through a combination of a greater grip height and a greater push height. At the athlete's competition run-up velocity (8.4 m/s) about one third of the rate of increase in peak height arose from an increase in grip height and about two thirds arose from an increase in push height. Across the range of run-up velocities examined here the athlete always performed the basic actions of running, planting, jumping, and inverting on the pole. However, he made minor systematic changes to his jumping kinematics, vaulting kinematics, and selection of pole characteristics as the run-up velocity increased. The increase in run-up velocity and changes in the athlete's vaulting kinematics resulted in substantial changes to the magnitudes of the energy exchanges during the vault. A faster run-up produced a greater loss of energy during the take-off, but this loss was not sufficient to negate the increase in run-up velocity and the increase in work done by the athlete during the pole support phase. The athlete therefore always had a net energy gain during the vault. However, the magnitude of this gain decreased slightly as run-up velocity increased. Key pointsIn the pole vault the optimum technique is to run-up as fast as possible.The athlete's vault height increases at a rate of about 0.5 m per 1 m/s increase in run-up velocity.The increase in vault height is achieved through a greater grip height and a greater push height. At the athlete's competition run-up velocity about one third of the rate of increase in vault height arises from an increase in grip height and two thirds arises from an increase in push height.The athlete has a net energy gain during the vault. A faster run-up velocity produces a greater loss of energy during the take-off but this loss of energy is not sufficient to negate the increase in run-up velocity and the increase in the work done by the athlete during the pole support phase. PMID:24149197

Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running.

PubMed

Johnson, R A; Rhodes, J S; Jeffrey, S L; Garland, T; Mitchell, G S

2003-01-01

Voluntary wheel running in rats increases hippocampal brain-derived neurotrophic factor (BDNF) expression, a neurochemical important for neuronal survival, differentiation, connectivity and synaptic plasticity. Here, we report the effects of wheel running on BDNF and neurotrophin-3 (NT-3) protein levels in normal control mice, and in mice selectively bred (25 generations) for increased voluntary wheel running. We hypothesized that increased voluntary wheel running in selected (S) mice would increase CNS BDNF and NT-3 protein levels more than in control (C) mice. Baseline hippocampal BDNF levels (mice housed without running wheels) were similar in S and C mice. Following seven nights of running, hippocampal BDNF increased significantly more in S versus C mice, and levels were correlated with distance run (considering C and S mice together). Spinal and cerebellar BDNF and hippocampal NT-3 levels were not significantly affected by wheel running in any group, but there was a small, positive correlation between spinal C3-C6 BDNF levels and distance run (considering C and S mice together). This is the first study to demonstrate that mice which choose to run more have greater elevations in hippocampal BDNF, suggesting enhanced potential for exercise-induced hippocampal neuroplasticity.

Hercules Aerospace flywheel test results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steele, R.S. Jr.; Babelay, E.F. Jr.; Sutton, B.J.

1981-06-01

The detailed results of the spin test evaluation of the Hercules Aerospace flywheel at the Oak Ridge Flywheel Evaluation Laboratory (ORFEL) are presented. Details of the static evaluation with radiography and measures of weight, inertia, and natural frequencies are included. The flywheel was spun four times with the maximum speed being increased with each run. During the final run, the flywheel achieved 372 rps and stored 0.714 kWhr of kinetic energy at 37 Whr/kg. The ultimate speed was limited by a composite transverse strength that was somewhat lower than that used in the design of the flywheel. This resulted inmore » internal cracking of the flywheel and, eventually, the loss of material from the outer circumference.« less

Rocker shoe, minimalist shoe, and standard running shoe: a comparison of running economy.

PubMed

Sobhani, Sobhan; Bredeweg, Steef; Dekker, Rienk; Kluitenberg, Bas; van den Heuvel, Edwin; Hijmans, Juha; Postema, Klaas

2014-05-01

Running with rocker shoes is believed to prevent lower limb injuries. However, it is not clear how running in these shoes affects the energy expenditure. The purpose of this study was, therefore, to assess the effects of rocker shoes on running economy in comparison with standard and minimalist running shoes. Cross-over design. Eighteen endurance female runners (age=23.6 ± 3 years), who were inexperienced in running with rocker shoes and with minimalist/barefoot running, participated in this study. Oxygen consumption, carbon dioxide production, heart rate and rate of perceived exertion were measured while participants completed a 6-min sub-maximal treadmill running test for each footwear condition. The data of the last 2 min of each shoe condition were averaged for analysis. A linear mixed model was used to compare differences among three footwear conditions. Oxygen consumption during running with rocker shoes was on average 4.5% higher than with the standard shoes (p<0.001) and 5.6% higher than with the minimalist shoe (p<0.001). No significant differences were found in heart rate and rate of perceived exertion across three shoe conditions. Female runners, who are not experienced in running with the rocker shoes and minimalist shoes, show more energy expenditure during running with the rocker shoes compared with the standard and minimalist shoes. As the studied shoes were of different masses, part of the effect of increased energy expenditure with the rocker shoe is likely to be due to its larger mass as compared with standard running shoes and minimalist shoes. Copyright © 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Individual responses to short-term heat acclimatisation as predictors of football performance in a hot, dry environment.

PubMed

Racinais, Sebastien; Mohr, Magni; Buchheit, Martin; Voss, Sven Christian; Gaoua, Nadia; Grantham, Justin; Nybo, Lars

2012-09-01

To identify the relationship between field performance in a hot environment and individual heat acclimatisation responses in football players. Nineteen semiprofessional football players completed a match in 21°C followed by 6 days of acclimatisation in dry heat (38-43°C, 12-30% relative humidity) and a match in ~43°C. A heat-response test (30 min walk+30 min seated; 44°C) was performed at the beginning and end of the acclimatisation period. The acclimatisation period increased sweat rate by 34% during a standard heat-exposure test and reduced sweat sodium concentration by 18% (both p≤0.005). Plasma volume changes showed large interindividual differences (-10 to +20%). Match-running performance was impaired in hot ambient condition and demonstrated marked interindividual differences (total distance -6.0±5.8%, high-intensity running -16.4±21.5%, both p≤0.002). Only haematological markers investigated during the heat-response test correlated with the ability of the player to cope with heat stress in a competitive situation; that is, changes in haematocrit between the heat-response tests were correlated to changes in total running during the game, r=-0.75; 90%CI [-0.88 to -0.51]. Heat acclimatisation responses and in turn, match-running performance in the heat, are highly individual. The players displaying the largest haematological adaptations were able to maintain the same activity when playing in the heat as when playing in temperate conditions. As such, team doctors might use acclimatisation indicators obtained from a heat-response test to predict the ability of individual players to cope with heat in competitive situations and individualise their preparation accordingly.

Mean platelet volume (MPV) predicts middle distance running performance.

PubMed

Lippi, Giuseppe; Salvagno, Gian Luca; Danese, Elisa; Skafidas, Spyros; Tarperi, Cantor; Guidi, Gian Cesare; Schena, Federico

2014-01-01

Running economy and performance in middle distance running depend on several physiological factors, which include anthropometric variables, functional characteristics, training volume and intensity. Since little information is available about hematological predictors of middle distance running time, we investigated whether some hematological parameters may be associated with middle distance running performance in a large sample of recreational runners. The study population consisted in 43 amateur runners (15 females, 28 males; median age 47 years), who successfully concluded a 21.1 km half-marathon at 75-85% of their maximal aerobic power (VO2max). Whole blood was collected 10 min before the run started and immediately thereafter, and hematological testing was completed within 2 hours after sample collection. The values of lymphocytes and eosinophils exhibited a significant decrease compared to pre-run values, whereas those of mean corpuscular volume (MCV), platelets, mean platelet volume (MPV), white blood cells (WBCs), neutrophils and monocytes were significantly increased after the run. In univariate analysis, significant associations with running time were found for pre-run values of hematocrit, hemoglobin, mean corpuscular hemoglobin (MCH), red blood cell distribution width (RDW), MPV, reticulocyte hemoglobin concentration (RetCHR), and post-run values of MCH, RDW, MPV, monocytes and RetCHR. In multivariate analysis, in which running time was entered as dependent variable whereas age, sex, blood lactate, body mass index, VO2max, mean training regimen and the hematological parameters significantly associated with running performance in univariate analysis were entered as independent variables, only MPV values before and after the trial remained significantly associated with running time. After adjustment for platelet count, the MPV value before the run (p = 0.042), but not thereafter (p = 0.247), remained significantly associated with running performance. The significant association between baseline MPV and running time suggest that hyperactive platelets may exert some pleiotropic effects on endurance performance.

Testing for the validity of purchasing power parity theory both in the long-run and the short-run for ASEAN-5

NASA Astrophysics Data System (ADS)

Choji, Niri Martha; Sek, Siok Kun

2017-11-01

The purchasing power parity theory says that the trade rates among two nations ought to be equivalent to the proportion of the total price levels between the two nations. For more than a decade, there has been substantial interest in testing for the validity of the Purchasing Power Parity (PPP) empirically. This paper performs a series of tests to see if PPP is valid for ASEAN-5 nations for the period of 2000-2016 using monthly data. For this purpose, we conducted four different tests of stationarity, two cointegration tests (Pedroni and Westerlund), and also the VAR model. The stationarity (unit root) tests reveal that the variables are not stationary at levels however stationary at first difference. Cointegration test results did not reject the H0 of no cointegration implying the absence long-run association among the variables and results of the VAR model did not reveal a strong short-run relationship. Based on the data, we, therefore, conclude that PPP is not valid in long-and short-run for ASEAN-5 during 2000-2016.

Match running performance and fitness in youth soccer.

PubMed

Buchheit, M; Mendez-Villanueva, A; Simpson, B M; Bourdon, P C

2010-11-01

The activity profiles of highly trained young soccer players were examined in relation to age, playing position and physical capacity. Time-motion analyses (global positioning system) were performed on 77 (U13-U18; fullbacks [FB], centre-backs [CB], midfielders [MD], wide midfielders [W], second strikers [2 (nd)S] and strikers [S]) during 42 international club games. Total distance covered (TD) and very high-intensity activities (VHIA; >16.1 km·h (-1)) were computed during 186 entire player-matches. Physical capacity was assessed via field test measures (e. g., peak running speed during an incremental field test, VVam-eval). Match running performance showed an increasing trend with age ( P<0.001, partial eta-squared (η (2)): 0.20-0.45). When adjusted for age and individual playing time, match running performance was position-dependent ( P<0.001, η (2): 0.13-0.40). MD covered the greater TD; CB the lowest ( P<0.05). Distance for VHIA was lower for CB compared with all other positions ( P<0.05); W and S displayed the highest VHIA ( P<0.05). Relationships between match running performance and physical capacities were position-dependent, with poor or non-significant correlations within FB, CB, MD and W (e. g., VHIA vs. VVam-eval: R=0.06 in FB) but large associations within 2 (nd)S and S positions (e. g., VHIA vs. VVam-eval: R=0.70 in 2 (nd)S). In highly trained young soccer players, the importance of fitness level as a determinant of match running performance should be regarded as a function of playing position.

Physiological responses of young thoroughbred horses to intermittent high-intensity treadmill training

PubMed Central

2013-01-01

Background Training of young Thoroughbred horses must balance development of cardiopulmonary function and aerobic capacity with loading of the musculoskeletal system that can potentially cause structural damage and/or lameness. High-speed equine treadmills are sometimes used to supplement exercise on a track in the training of young Thoroughbreds because the horse can run at high speeds but without the added weight of a rider. We tested the hypothesis that intermittent high-intensity exercise on a treadmill of young Thoroughbred horses entering training can enhance development of aerobic capacity (Vo2max) and running performance more than conventional training under saddle, and do so without causing lameness. Results Twelve yearling Thoroughbreds trained for 8 months with conventional riding (C) only, conventional riding plus a short (2 month, S) interval of once-per-week high-intensity treadmill exercise, or a long (8 month, L) interval of once-per-week high-intensity treadmill exercise. Three treadmill exercise tests evaluated Vo2max, oxygen transport and running performance variables in June of the yearling year (only for L), October of the yearling year and April of the 2-year-old year. No horses experienced lameness during the study. Aerobic capacity increased in all groups after training. In both October and April, Vo2max in L was higher than in C, but did not differ between L and S or S and C. Running speeds eliciting Vo2max also increased in all groups after training, with S (809 ± 3 m/s) and L (804 ± 9 m/s) higher than C (764 ± 27 m/s). Maximum heart rate decreased for all groups after training. Hematocrit and hemoglobin concentration increased for L throughout training. Conclusions Young Thoroughbred horses can increase aerobic capacity and running performance more than by strictly using track training under saddle with the addition of intermittent high-intensity treadmill exercise, and they can do so without experiencing lameness. This finding suggests that young racehorses might be able to achieve higher aerobic fitness during training without subjecting their musculoskeletal systems to increased loading and risk of developing lameness. The findings of this preliminary study do not indicate a specific protocol to best achieve this goal. PMID:23957961

Thermoregulatory responses to skin wetting during prolonged treadmill running.

PubMed

Bassett, D R; Nagle, F J; Mookerjee, S; Darr, K C; Ng, A V; Voss, S G; Napp, J P

1987-02-01

We examined the physiological responses to skin wetting during a 120-min level treadmill run to assess whether skin wetting would reduce the dehydration and the increase in core temperature associated with prolonged exercise. Testing was conducted in an environmental chamber (T = 29.5 degrees C, wind velocity = 3 m X sec-1) under two different humidity conditions (33 or 66% relative humidity). Ten male subjects performed two runs in each humidity condition; one served as a control run. The other included spraying the body with 50 ml of water (T = 29.5 degrees C) every 10 min. Spraying had no effect on rectal temperature (Tre), heart rate, oxygen consumption, perceived exertion, sweat loss, or percent change in plasma volume in both the humid and the dry conditions. Spraying produced a significant reduction in mean skin temperature (Tsk), which increased the (Tre - Tsk) gradient. At the same time, overall skin conductance (K) was decreased, presumably as a result of cutaneous vasoconstriction due to the low Tsk. Since heat transfer from the body's core to the skin is expressed by the equation: heat transfer = K X (Tre - Tsk) the spraying had no effect on heat transfer away from the core, and Tre remained unchanged.

Effect of resistance training regimens on treadmill running and neuromuscular performance in recreational endurance runners.

PubMed

Mikkola, Jussi; Vesterinen, Ville; Taipale, Ritva; Capostagno, Benoit; Häkkinen, Keijo; Nummela, Ari

2011-10-01

The purpose of this study was to assess the effects of heavy resistance, explosive resistance, and muscle endurance training on neuromuscular, endurance, and high-intensity running performance in recreational endurance runners. Twenty-seven male runners were divided into one of three groups: heavy resistance, explosive resistance or muscle endurance training. After 6 weeks of preparatory training, the groups underwent an 8-week resistance training programme as a supplement to endurance training. Before and after the 8-week training period, maximal strength (one-repetition maximum), electromyographic activity of the leg extensors, countermovement jump height, maximal speed in the maximal anaerobic running test, maximal endurance performance, maximal oxygen uptake ([V·]O(₂max)), and running economy were assessed. Maximal strength improved in the heavy (P = 0.034, effect size ES = 0.38) and explosive resistance training groups (P = 0.003, ES = 0.67) with increases in leg muscle activation (heavy: P = 0.032, ES = 0.38; explosive: P = 0.002, ES = 0.77). Only the heavy resistance training group improved maximal running speed in the maximal anaerobic running test (P = 0.012, ES = 0.52) and jump height (P = 0.006, ES = 0.59). Maximal endurance running performance was improved in all groups (heavy: P = 0.005, ES = 0.56; explosive: P = 0.034, ES = 0.39; muscle endurance: P = 0.001, ES = 0.94), with small though not statistically significant improvements in [V·]O(₂max) (heavy: ES = 0.08; explosive: ES = 0.29; muscle endurance: ES = 0.65) and running economy (ES in all groups < 0.08). All three modes of strength training used concurrently with endurance training were effective in improving treadmill running endurance performance. However, both heavy and explosive strength training were beneficial in improving neuromuscular characteristics, and heavy resistance training in particular contributed to improvements in high-intensity running characteristics. Thus, endurance runners should include heavy resistance training in their training programmes to enhance endurance performance, such as improving sprinting ability at the end of a race.

Effects of Physical Training and Fitness on Running Injuries in Physically Active Young Men.

PubMed

Grier, Tyson L; Canham-Chervak, Michelle; Anderson, Morgan K; Bushman, Timothy T; Jones, Bruce H

2017-01-01

Grier, TL, Canham-Chervak, M, Anderson, MK, Bushman, TT, and Jones, BH. Effects of physical training and fitness on running injuries in physically active young men. J Strength Cond Res 31(1): 207-216, 2017-The purpose of this investigation was to determine the effects of physical training (PT) and fitness on risks for running-related injuries (RRIs) in physically active young men. Personal characteristics, PT, Army Physical Fitness Test scores, and injury data were obtained by survey. Army Physical Fitness Test variables (push-ups, sit-ups, and 2-mile run) were converted into quartiles (Q), where Q1 = lowest performance and Q4 = highest performance. Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated using multivariate logistic regression. Over 4,000 (n = 4,236) soldiers were surveyed. Running injury incidence was 14%. A greater risk of an RRI was associated with older age (OR31+/<22 years = 1.62, 95% CI, 1.21-2.18), higher BMI ((Equation is included in full-text article.)), and total distance ran per week during unit PT (OR16.1+/1-5 miles = 1.66, 95% CI, 1.15-2.41). A lower risk of an RRI was associated with total distance run per week during personal PT (OR5.1-10/1-5 miles = 0.70, 95% CI, 0.53-0.91, OR10.1-16 +/1-5 miles = 0.58, 95% CI, 0.35-0.97, OR16.1+/1-5 miles = 0.54, 95% CI, 0.30-0.98), higher aerobic endurance as measured by 2-mile run performance (ORQ4/Q1 = 0.50, 95% CI, 0.35-0.72), and unit resistance training ≥3 times a week (OR≥3 times per week/none = 0.46, 95% CI, 0.29-0.73). Greater personal PT running mileage decreased injuries in this population suggesting that the increased protective effect of higher aerobic fitness outweighed the injurious effect of running more miles during personal PT. Countermeasures to prevent RRIs could entail enhancing aerobic endurance, providing opportunities for personal aerobic training, monitoring for excessive unit PT running mileage and encouraging unit resistance training ≥3 times per week.

Health-Related Physical Fitness in Healthy Untrained Men: Effects on VO2max, Jump Performance and Flexibility of Soccer and Moderate-Intensity Continuous Running

PubMed Central

Milanović, Zoran; Pantelić, Saša; Sporiš, Goran; Mohr, Magni; Krustrup, Peter

2015-01-01

The purpose of this study was to determine the effects of recreational soccer (SOC) compared to moderate-intensity continuous running (RUN) on all health-related physical fitness components in healthy untrained men. Sixty-nine participants were recruited and randomly assigned to one of three groups, of which sixty-four completed the study: a soccer training group (SOC; n = 20, 34±4 (means±SD) years, 78.1±8.3 kg, 179±4 cm); a running group (RUN; n = 21, 32±4 years, 78.0±5.5 kg, 179±7 cm); or a passive control group (CON; n = 23, 30±3 years, 76.6±12.0 kg, 178±8 cm). The training intervention lasted 12 weeks and consisted of three 60-min sessions per week. All participants were tested for each of the following physical fitness components: maximal aerobic power, minute ventilation, maximal heart rate, squat jump (SJ), countermovement jump with arm swing (CMJ), sit-and-reach flexibility, and body composition. Over the 12 weeks, VO2max relative to body weight increased more (p<0.05) in SOC (24.2%, ES = 1.20) and RUN (21.5%, ES = 1.17) than in CON (-5.0%, ES = -0.24), partly due to large changes in body mass (-5.9, -5.7 and +2.6 kg, p<0.05 for SOC, RUN and CON, respectively). Over the 12 weeks, SJ and CMJ performance increased more (p<0.05) in SOC (14.8 and 12.1%, ES = 1.08 and 0.81) than in RUN (3.3 and 3.0%, ES = 0.23 and 0.19) and CON (0.3 and 0.2%), while flexibility also increased more (p<0.05) in SOC (94%, ES = 0.97) than in RUN and CON (0–2%). In conclusion, untrained men displayed marked improvements in maximal aerobic power after 12 weeks of soccer training and moderate-intensity running, partly due to large decreases in body mass. Additionally soccer training induced pronounced positive effects on jump performance and flexibility, making soccer an effective broad-spectrum fitness training intervention. PMID:26305880

Stereological Study on the Positive Effect of Running Exercise on the Capillaries in the Hippocampus in a Depression Model.

PubMed

Chen, Linmu; Zhou, Chunni; Tan, Chuanxue; Wang, Feifei; Gao, Yuan; Huang, Chunxia; Zhang, Yi; Jiang, Lin; Tang, Yong

2017-01-01

Running exercise is an effective method to improve depressive symptoms when combined with drugs. However, the underlying mechanisms are not fully clear. Cerebral blood flow perfusion in depressed patients is significantly lower in the hippocampus. Physical activity can achieve cerebrovascular benefits. The purpose of this study was to evaluate the impacts of running exercise on capillaries in the hippocampal CA1 and dentate gyrus (DG) regions. The chronic unpredictable stress (CUS) depression model was used in this study. CUS rats were given 4 weeks of running exercise from the fifth week to the eighth week (20 min every day from Monday to Friday each week). The sucrose consumption test was used to measure anhedonia. Furthermore, stereological methods were used to investigate the capillary changes among the control group, CUS/Standard group and CUS/Running group. Sucrose consumption significantly increased in the CUS/Running group. Running exercise has positive effects on the capillaries parameters in the hippocampal CA1 and DG regions, such as the total volume, total length and total surface area. These results demonstrated that capillaries are protected by running exercise in the hippocampal CA1 and DG might be one of the structural bases for the exercise-induced treatment of depression-like behavior. These results suggest that drugs and behavior influence capillaries and may be considered as a new means for depression treatment in the future.

Graduated Compression Stockings for Runners: Friend, Foe, or Fake?

PubMed Central

Bovenschen, H. Jorn; te Booij, Mariëlle; van der Vleuten, Carine J. M.

2013-01-01

Objective: To assess the effect of graduated compression stockings (GCS) on lower leg volume and leg complaints in runners during and after exercise. Design: Cross-sectional study. Setting: Radboud University Nijmegen Medical Centre and an outdoor running track in Nijmegen, The Netherlands. Patients or Other Participants: Thirteen Dutch trained recreational runners. Intervention(s): Participants used a GCS on 1 leg during running. Main Outcome Measures: (1) Lower leg volume of both legs was measured at baseline, directly after running, and at 5 minutes and 30 minutes after running using a validated perometer. (2) Leg complaints were reported on questionnaires at set intervals. Results: (1) In both experiments, the legs with GCS showed a reduction in mean (± SEM) leg volume directly after running, as compared with the leg without GCS: −14.1 ± 7.6 mL (P = .04) for the 10-km running track and −53.5 ± 17.8 mL (P = .03) for the maximum exercise test. This effect was not observed at 5 and 30 minutes after running. (2) No differences in leg complaints were reported in either experiment. Conclusions: The GCS prevented an increase in leg volume just after the running exercise. However, this result was not accompanied by a reduction in subjective questionnaire-reported leg complaints. The practical consequences of the present findings need further study. PMID:23672387

Running exercise protects the capillaries in white matter in a rat model of depression.

PubMed

Chen, Lin-Mu; Zhang, Ai-Pin; Wang, Fei-Fei; Tan, Chuan-Xue; Gao, Yuan; Huang, Chun-Xia; Zhang, Yi; Jiang, Lin; Zhou, Chun-Ni; Chao, Feng-Lei; Zhang, Lei; Tang, Yong

2016-12-01

Running has been shown to improve depressive symptoms when used as an adjunct to medication. However, the mechanisms underlying the antidepressant effects of running are not fully understood. Changes of capillaries in white matter have been discovered in clinical patients and depression model rats. Considering the important part of white matter in depression, running may cause capillary structural changes in white matter. Chronic unpredictable stress (CUS) rats were provided with a 4-week running exercise (from the fifth week to the eighth week) for 20 minutes each day for 5 consecutive days each week. Anhedonia was measured by a behavior test. Furthermore, capillary changes were investigated in the control group, the CUS/Standard group, and the CUS/Running group using stereological methods. The 4-week running increased sucrose consumption significantly in the CUS/Running group and had significant effects on the total volume, total length, and total surface area of the capillaries in the white matter of depression rats. These results demonstrated that exercise-induced protection of the capillaries in white matter might be one of the structural bases for the exercise-induced treatment of depression. It might provide important parameters for further study of the vascular mechanisms of depression and a new research direction for the development of clinical antidepressant means. J. Comp. Neurol. 524:3577-3586, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Self-Reported Minimalist Running Injury Incidence and Severity: A Pilot Study.

PubMed

Ostermann, Katrina; Ridpath, Lance; Hanna, Jandy B

2016-08-01

Minimalist running entails using shoes with a flexible thin sole and is popular in the United States. Existing literature disagrees over whether minimalist running shoes (MRS) improve perceived severity of injuries associated with running in traditional running shoes (TRS). Additionally, the perceived injury patterns associated with MRS are relatively unknown. To examine whether injury incidence and severity (ie, degree of pain) by body region change after switching to MRS, and to determine if transition times affect injury incidences or severity with MRS. Runners who were either current or previous users of MRS were recruited to complete an Internet-based survey regarding self-reported injury before switching to MRS and whether self-reported pain from that injury decreased after switching. Questions regarding whether new injuries developed in respondents after switching to MRS were also included. Analyses were calculated using t tests, Wilcoxon signed rank tests, and Fischer exact tests. Forty-seven runners completed the survey, and 16 respondents reported injuries before switching to MRS. Among these respondents, pain resulting from injuries of the feet (P=.03) and knees (P=.01) decreased. Eighteen respondents (38.3%) indicated they sustained new injuries after switching to MRS, but the severity of these did not differ significantly from no injury. Neither time allowed for transition to MRS nor use or disuse of a stretching routine during this period was correlated with an increase in the incidence or severity of injuries. After switching to MRS, respondents perceived an improvement in foot and knee injuries. Additionally, respondents using MRS reported an injury rate of 38.3%, compared with the approximately 64% that the literature reports among TRS users. Future studies should be expanded to determine the full extent of the differences in injury patterns between MRS and TRS.

Electrochemical disinfection of repeatedly recycled blackwater in a free‐standing, additive‐free toilet

PubMed Central

Sellgren, Katelyn L.; Klem, Ethan J. D.; Piascik, Jeffrey R.; Stoner, Brian R.

2017-01-01

Abstract Decentralized, energy‐efficient waste water treatment technologies enabling water reuse are needed to sustainably address sanitation needs in water‐ and energy‐scarce environments. Here, we describe the effects of repeated recycling of disinfected blackwater (as flush liquid) on the energy required to achieve full disinfection with an electrochemical process in a prototype toilet system. The recycled liquid rapidly reached a steady state with total solids reliably ranging between 0.50 and 0.65% and conductivity between 20 and 23 mS/cm through many flush cycles over 15 weeks. The increase in accumulated solids was associated with increased energy demand and wide variation in the free chlorine contact time required to achieve complete disinfection. Further studies on the system at steady state revealed that running at higher voltage modestly improves energy efficiency, and established running parameters that reliably achieve disinfection at fixed run times. These results will guide prototype testing in the field. PMID:29242713

Modeling of Aerodynamic Force Acting in Tunnel for Analysis of Riding Comfort in a Train

NASA Astrophysics Data System (ADS)

Kikko, Satoshi; Tanifuji, Katsuya; Sakanoue, Kei; Nanba, Kouichiro

In this paper, we aimed to model the aerodynamic force that acts on a train running at high speed in a tunnel. An analytical model of the aerodynamic force is developed from pressure data measured on car-body sides of a test train running at the maximum revenue operation speed. The simulation of an 8-car train running while being subjected to the modeled aerodynamic force gives the following results. The simulated car-body vibration corresponds to the actual vibration both qualitatively and quantitatively for the cars at the rear of the train. The separation of the airflow at the tail-end of the train increases the yawing vibration of the tail-end car while it has little effect on the car-body vibration of the adjoining car. Also, the effect of the moving velocity of the aerodynamic force on the car-body vibration is clarified that the simulation under the assumption of a stationary aerodynamic force can markedly increase the car-body vibration.

Comparison of gradual and rapid onset runs in a short-arm centrifugation

NASA Astrophysics Data System (ADS)

Miyamoto, A.; Saga, K.; Kinoue, T.; Nakazato, T.; Hirayanagi, K.; Yajima, K.; Hayashi, S.; Matsumoto, S.

A gradual onset run (GOR) in a short-arm centrifugation was performed on ten healthy students. The centrifuge had a 1.8 m radius, and the subjects sat on a chair in a cabin. The Gz force increased to 2.2 Gz at 0.1 °/sec 2 for 32 min. and the same Gz-level was maintained for 20 min. Three out of ten subjects completed the whole protocol; the load on the others was terminated because of symptoms or increased heart rate. There were few symptoms such as vertigo, that was a common problem with a rapid onset run (ROR) in former experiments, due to the short-arm centrifugation. The changes of the flicker test after the load were much less in the GOR protocol than in the ROR protocol, even in the terminated group. GOR seemed preferable to ROR in preventing vertigo even though it took longer to reach the necessary G load.

Pyrotechnic hazards classification and evaluation program. Run-up reaction testing in pyrotechnic dust suspensions

NASA Technical Reports Server (NTRS)

1971-01-01

A preliminary investigation of the parameters included in run-up dust reactions is presented. Two types of tests were conducted: (1) ignition criteria of large bulk pyrotechnic dusts, and (2) optimal run-up conditions of large bulk pyrotechnic dusts. These tests were used to evaluate the order of magnitude and gross scale requirements needed to induce run-up reactions in pyrotechnic dusts and to simulate at reduced scale an accident that occurred in a manufacturing installation. Test results showed that propagation of pyrotechnic dust clouds resulted in a fireball of relatively long duration and large size. In addition, a plane wave front was observed to travel down the length of the gallery.

Acute Lower Extremity Running Kinematics After a Hamstring Stretch

PubMed Central

Davis Hammonds, Autumn L.; Laudner, Kevin G.; McCaw, Steve; McLoda, Todd A.

2012-01-01

Context: Limited passive hamstring flexibility might affect kinematics, performance, and injury risk during running. Pre-activity static straight-leg raise stretching often is used to gain passive hamstring flexibility. Objective: To investigate the acute effects of a single session of passive hamstring stretching on pelvic, hip, and knee kinematics during the swing phase of running. Design: Randomized controlled clinical trial. Setting: Biomechanics research laboratory. Patients or Other Participants: Thirty-four male (age = 21.2 ± 1.4 years) and female (age = 21.3±2.0 years) recreational athletes. Intervention(s): Participants performed treadmill running pretests and posttests at 70% of their age-predicted maximum heart rate. Pelvis, hip, and knee joint angles during the swing phase of 5 consecutive gait cycles were collected using a motion analysis system. Right and left hamstrings of the intervention group participants were passively stretched 3 times for 30 seconds in random order immediately after the pretest. Control group participants performed no stretching or movement between running sessions. Main Outcome Measure(s): Six 2-way analyses of variance to determine joint angle differences between groups at maximum hip flexion and maximum knee extension with an α level of .008. Results: Flexibility increased between pretest and post-test in all participants (F1,30 = 80.61, P<.001). Anterior pelvic tilt (F1,30 = 0.73, P=.40), hip flexion (F1,30 = 2.44, P=.13), and knee extension (F1,30 = 0.06, P=.80) at maximum hip flexion were similar between groups throughout testing. Anterior pelvic tilt (F1,30 = 0.69, P=.41), hip flexion (F1,30 = 0.23, P=.64), and knee extension (F1,30 = 3.38, P=.62) at maximum knee extension were similar between groups throughout testing. Men demonstrated greater anterior pelvic tilt than women at maximum knee extension (F1,30 = 13.62, P=.001). Conclusions: A single session of 3 straight-leg raise hamstring stretches did not change pelvis, hip, or knee running kinematics. PMID:22488225

Chronic and acute inspiratory muscle loading augment the effect of a 6-week interval program on tolerance of high-intensity intermittent bouts of running.

PubMed

Tong, Tom K; Fu, Frank H; Eston, Roger; Chung, Pak-Kwong; Quach, Binh; Lu, Kui

2010-11-01

This study examined the hypothesis that chronic (training) and acute (warm-up) loaded ventilatory activities applied to the inspiratory muscles (IM) in an integrated manner would augment the training volume of an interval running program. This in turn would result in additional improvement in the maximum performance of the Yo-Yo intermittent recovery test in comparison with interval training alone. Eighteen male nonprofessional athletes were allocated to either an inspiratory muscle loading (IML) group or control group. Both groups participated in a 6-week interval running program consisting of 3-4 workouts (1-3 sets of various repetitions of selected distance [100-2,400 m] per workout) per week. For the IML group, 4-week IM training (30 inspiratory efforts at 50% maximal static inspiratory pressure [P0] per set, 2 sets·d-1, 6 d·wk-1) was applied before the interval program. Specific IM warm-up (2 sets of 30 inspiratory efforts at 40% P0) was performed before each workout of the program. For the control group, neither IML was applied. In comparison with the control group, the interval training volume as indicated by the repeatability of running bouts at high intensity was approximately 27% greater in the IML group. Greater increase in the maximum performance of the Yo-Yo test (control: 16.9 ± 5.5%; IML: 30.7 ± 4.7% baseline value) was also observed after training. The enhanced exercise performance was partly attributable to the greater reductions in the sensation of breathlessness and whole-body metabolic stress during the Yo-Yo test. These findings show that the combination of chronic and acute IML into a high-intensity interval running program is a beneficial training strategy for enhancing the tolerance to high-intensity intermittent bouts of running.

Bridge Crossing Simulator

DTIC Science & Technology

2014-10-07

is counted as. Per the TDTC, a test bridge with longitudinal and/or lateral symmetry under non- eccentric loading can be considered as 1, 2, or 4...Level Run036 3 MLC70T (tracked) BA Run046 6 AB Run055 9 AB Run060 9 BA Run064 12 BA Run071 15 AB Run155 3 MLC96W ( wheeled ) AB...Run331 9 AB Run359 15 AB Run430 12 MLC96W ( wheeled ) BA Run434 12 AB Run447 3 BA Bank Condition: Side Slope, Even Strain Channels High

Experience in Grid Site Testing for ATLAS, CMS and LHCb with HammerCloud

NASA Astrophysics Data System (ADS)

Elmsheuser, Johannes; Medrano Llamas, Ramón; Legger, Federica; Sciabà, Andrea; Sciacca, Gianfranco; Úbeda García, Mario; van der Ster, Daniel

2012-12-01

Frequent validation and stress testing of the network, storage and CPU resources of a grid site is essential to achieve high performance and reliability. HammerCloud was previously introduced with the goals of enabling VO- and site-administrators to run such tests in an automated or on-demand manner. The ATLAS, CMS and LHCb experiments have all developed VO plugins for the service and have successfully integrated it into their grid operations infrastructures. This work will present the experience in running HammerCloud at full scale for more than 3 years and present solutions to the scalability issues faced by the service. First, we will show the particular challenges faced when integrating with CMS and LHCb offline computing, including customized dashboards to show site validation reports for the VOs and a new API to tightly integrate with the LHCbDIRAC Resource Status System. Next, a study of the automatic site exclusion component used by ATLAS will be presented along with results for tuning the exclusion policies. A study of the historical test results for ATLAS, CMS and LHCb will be presented, including comparisons between the experiments’ grid availabilities and a search for site-based or temporal failure correlations. Finally, we will look to future plans that will allow users to gain new insights into the test results; these include developments to allow increased testing concurrency, increased scale in the number of metrics recorded per test job (up to hundreds), and increased scale in the historical job information (up to many millions of jobs per VO).

Sexually dimorphic effects of postnatal treatment on the development of activity-based anorexia in adolescent and adult rats.

PubMed

Hancock, Stephanie D; Grant, Virginia L

2009-12-01

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis is a marked feature of anorexia nervosa. Using a modified version of the activity-based animal model of anorexia nervosa, we examine whether factors known to affect HPA axis activity influence the development of activity-based anorexia (ABA). Male and female rats were subjected to maternal separation or handling procedures during the first two postnatal weeks and tested in a mild version of the ABA paradigm, comprised of 2-hr daily running wheel access followed by 1-hr food access, either in adolescence or adulthood. Compared to handled females, maternally separated females demonstrated greater increases in wheel running and a more pronounced running-induced suppression of food intake during adolescence, but not in adulthood. In contrast, it was only in adulthood that wheel running produced more prolonged anorexic effects in maternally separated than in handled males. These findings highlight the interplay between early postnatal treatment, sex of the animal, and developmental age on running, food intake, and rate of body weight loss in a mild version of the ABA paradigm.

Voluntary Running-Wheel Exercise Decreases the Threshold for Rewarding Intracranial Self-Stimulation

PubMed Central

Morris, Michael J.; Na, Elisa S.; Johnson, Alan Kim

2015-01-01

Physical exercise has mood-enhancing and antidepressant properties although the mechanisms underlying these effects are not known. The present experiment investigated the effects of prolonged access to a running wheel on electrical self-stimulation of the lateral hypothalamus (LHSS), a measure of hedonic state, in rats. Rats with continuous voluntary access to a running wheel for either 2 or 5 weeks exhibited dramatic leftward shifts in the effective current 50 (ECu50; current value that supports half of maximum responding) of their LHSS current-response functions compared to their baselines, indicating a decrease in reward threshold, whereas control rats current-response functions after 2 or 5 weeks were not significantly different from baseline. An inverse correlation existed between the change in ECu50 from baseline and the amount an animal had run in the day prior to LHSS testing, indicating that animals that exhibited higher levels of running showed a more robust decrease in LHSS threshold. We conclude that long-term voluntary exercise increases sensitivity to rewarding stimuli, which may contribute to its antidepressant properties. PMID:22845707

Voluntary running-wheel exercise decreases the threshold for rewarding intracranial self-stimulation.

PubMed

Morris, Michael J; Na, Elisa S; Johnson, Alan Kim

2012-08-01

Physical exercise has mood-enhancing and antidepressant properties although the mechanisms underlying these effects are not known. The present experiment investigated the effects of prolonged access to a running wheel on electrical self-stimulation of the lateral hypothalamus (LHSS), a measure of hedonic state, in rats. Rats with continuous voluntary access to a running wheel for either 2 or 5 weeks exhibited dramatic leftward shifts in the effective current 50 (ECu50; current value that supports half of maximum responding) of their LHSS current-response functions compared to their baselines, indicating a decrease in reward threshold, whereas control rats current-response functions after 2 or 5 weeks were not significantly different from baseline. An inverse correlation existed between the change in ECu50 from baseline and the amount an animal had run in the day prior to LHSS testing, indicating that animals that exhibited higher levels of running showed a more robust decrease in LHSS threshold. We conclude that long-term voluntary exercise increases sensitivity to rewarding stimuli, which may contribute to its antidepressant properties.

Voluntary Wheel Running Does not Affect Lipopolysaccharide-Induced Depressive-Like Behavior in Young Adult and Aged Mice

PubMed Central

Martin, Stephen A.; Dantzer, Robert; Kelley, Keith W.; Woods, Jeffrey A.

2014-01-01

Peripheral stimulation of the innate immune system with lipopolysaccharide (LPS) causes prolonged depressive-like behavior in aged mice that is dependent on indoleamine 2,3 dioxygenase (IDO) activation. Regular moderate intensity exercise training has been shown to exert neuroprotective effects that might reduce depressive-like behavior in aged mice. The purpose of this study was to test the hypothesis that voluntary wheel running would attenuate LPS-induced depressive-like behavior and brain IDO gene expression in 4-month-old and 22-month-old C57BL/6J mice. Mice were housed with a running wheel (Voluntary Wheel Running, VWR) or no wheel (Standard) for 30 days (young adult mice) or 70 days (aged mice), after which they were intraperitoneally injected with LPS (young adult mice: 0.83 mg/kg; aged mice: 0.33 mg/kg). Young adult VWR mice ran on average 6.9 km/day, while aged VWR mice ran on average 3.4 km/day. Both young adult and aged VWR mice increased their forced exercise tolerance compared to their respective Standard control groups. VWR had no effect on LPS-induced anorexia, weight-loss, increased immobility in the tail suspension test, and decreased sucrose preference in either young adult or aged mice. Four (young adult mice) and twenty-four (aged mice) hours after injection of LPS transcripts for TNF-α, IL-1β, IL-6, and IDO were upregulated in the whole brain independently of VWR. These results indicate that prolonged physical exercise has no effect on the neuroinflammatory response to LPS and its behavioral consequences. PMID:24281669

Voluntary Exercise Produces Antidepressant and Anxiolytic Behavioral Effects in Mice

PubMed Central

Duman, Catharine H.; Schlesinger, Lee; Russell, David S.; Duman, Ronald S.

2008-01-01

Reports of beneficial effects of exercise on psychological health in humans are increasingly supported by basic research studies. Exercise is hypothesized to regulate antidepressant-related mechanisms and we therefore characterized the effects of chronic exercise in mouse behavioral paradigms relevant to antidepressant actions. Mice given free access to running wheels showed antidepressant-like behavior in learned helplessness, forced-swim (FST) and tail suspension paradigms. These responses were similar to responses of antidepressant drug-treated animals. When tested under conditions where locomotor activity was not altered, exercising mice also showed reduced anxiety compared to sedentary control mice. In situ hybridization analysis showed that BDNF mRNA was increased in specific subfields of hippocampus after wheel running. We chose one paradigm, the FST, in which to investigate a functional role for brain-derived neurotrophic factor (BDNF) in the behavioral response to exercise. We tested mice heterozygous for a deletion of the BDNF gene in the FST after wheel-running. Exercising wild-type mice showed the expected antidepressant-like behavioral response in the FST but exercise was ineffective in improving FST performance in heterozygous BDNF knockout mice. A possible functional contribution of a BDNF signaling pathway to FST performance in exercising mice was investigated using the specific MEK inhibitor PD184161 to block the MAPK signaling pathway. Subchronic administration of PD184161 to exercising mice blocked the antidepressant-like behavioral response seen in vehicle-treated exercising mice in the FST. In summary, chronic wheel-running exercise in mice results in antidepressant-like behavioral changes that may involve a BDNF related mechanism similar to that hypothesized for antidepressant drug treatment. PMID:18267317

40 CFR Table 6 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Incinerators on and After [Date to be specified in...

Code of Federal Regulations, 2012 CFR

2012-07-01

... per million dry volume 3-run average (1 hour minimum sample time per run) Performance test (Method 10... (Reapproved 2008) c. Oxides of nitrogen 53 parts per million dry volume 3-run average (1 hour minimum sample... average (1 hour minimum sample time per run) Performance test (Method 6 or 6c at 40 CFR part 60, appendix...

40 CFR Table 6 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Incinerators on and After [Date to be specified in...

Code of Federal Regulations, 2011 CFR

2011-07-01

... per million dry volume 3-run average (1 hour minimum sample time per run) Performance test (Method 10... (Reapproved 2008) c. Oxides of nitrogen 53 parts per million dry volume 3-run average (1 hour minimum sample... average (1 hour minimum sample time per run) Performance test (Method 6 or 6c at 40 CFR part 60, appendix...

40 CFR Table 2 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Incinerators Before [Date to be specified in state...

Code of Federal Regulations, 2014 CFR

2014-07-01

... parts per million by dry volume 3-run average (1 hour minimum sample time per run) Performance test..., appendix A-4). Oxides of nitrogen 388 parts per million by dry volume 3-run average (1 hour minimum sample... (1 hour minimum sample time per run) Performance test (Method 6 or 6c of appendix A of this part) a...

40 CFR Table 2 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Incinerators Before [Date to be specified in state...

Code of Federal Regulations, 2013 CFR

2013-07-01

... parts per million by dry volume 3-run average (1 hour minimum sample time per run) Performance test..., appendix A-4). Oxides of nitrogen 388 parts per million by dry volume 3-run average (1 hour minimum sample... (1 hour minimum sample time per run) Performance test (Method 6 or 6c of appendix A of this part) a...

Voluntary physical activity prevents insulin resistance in a tissue specific manner.

PubMed

Sarvas, Jessica L; Otis, Jeffrey S; Khaper, Neelam; Lees, Simon J

2015-02-01

Physical inactivity and a sedentary lifestyle are risk factors for the development of type 2 diabetes. Here, we identified the effects 8 weeks of voluntary physical activity had on the prevention of insulin resistance in mouse skeletal muscles and liver (a hallmark of T2D). To do this, 8 week old C57BL/6J mice with (RUN) and without (SED) voluntary access to running wheels were fed a standard rodent chow ad libitum for 8 weeks. In the liver, there was a 2.5-fold increase in insulin stimulated Akt(SER) (473) phosphorylation, and a threefold increase in insulin-stimulated (0.5 U/kg) GSK3β(SER) (9) phosphorylation in RUN compared to SED mice. Although not induced in skeletal muscles, there was a twofold increase in SOCS3 expression in SED compared to RUN mice in the liver. There was no difference in the glucose tolerance test between groups. This study was the first to show differences in liver insulin sensitivity after 8 weeks of voluntary physical activity, and increased SOCS3 expression in the liver of sedentary mice compared to active mice. These findings demonstrate that even in young mice that would normally be considered healthy, the lack of physical activity leads to insulin resistance representing the initial pathogenesis of impaired glucose metabolism leading to type 2 diabetes. © 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

The bending stiffness of shoes is beneficial to running energetics if it does not disturb the natural MTP joint flexion.

PubMed

Oh, Keonyoung; Park, Sukyung

2017-02-28

A local minimum for running energetics has been reported for a specific bending stiffness, implying that shoe stiffness assists in running propulsion. However, the determinant of the metabolic optimum remains unknown. Highly stiff shoes significantly increase the moment arm of the ground reaction force (GRF) and reduce the leverage effect of joint torque at ground push-off. Inspired by previous findings, we hypothesized that the restriction of the natural metatarsophalangeal (MTP) flexion caused by stiffened shoes and the corresponding joint torque changes may reduce the benefit of shoe bending stiffness to running energetics. We proposed the critical stiffness, k cr , which is defined as the ratio of the MTP joint (MTPJ) torque to the maximal MTPJ flexion angle, as a possible threshold of the elastic benefit of shoe stiffness. 19 subjects participated in a running test while wearing insoles with five different bending stiffness levels. Joint angles, GRFs, and metabolic costs were measured and analyzed as functions of the shoe stiffness. No significant changes were found in the take-off velocity of the center of mass (CoM), but the horizontal ground push-offs were significantly reduced at different shoe stiffness levels, indicating that complementary changes in the lower-limb joint torques were introduced to maintain steady running. Slight increases in the ankle, knee, and hip joint angular impulses were observed at stiffness levels exceeding the critical stiffness, whereas the angular impulse at the MTPJ was significantly reduced. These results indicate that the shoe bending stiffness is beneficial to running energetics if it does not disturb the natural MTPJ flexion. Copyright © 2017 Elsevier Ltd. All rights reserved.

40 CFR 75.81 - Monitoring of Hg mass emissions and heat input at the unit level.

Code of Federal Regulations, 2010 CFR

2010-07-01

... concentration (µg/scm) from any of the test runs or 0.50 µg/scm, whichever is greater Qmax = Maximum potential...” in Equation 1. Also, note that if the highest Hg concentration measured in any test run is less than... updated value shall either be the highest Hg concentration measured in any of the test runs or 0.50 µg/scm...

Seasonal variations in body composition, maximal oxygen uptake, and gas exchange threshold in cross-country skiers.

PubMed

Polat, Metin; Korkmaz Eryılmaz, Selcen; Aydoğan, Sami

2018-01-01

In order to ensure that athletes achieve their highest performance levels during competitive seasons, monitoring their long-term performance data is crucial for understanding the impact of ongoing training programs and evaluating training strategies. The present study was thus designed to investigate the variations in body composition, maximal oxygen uptake (VO 2max ), and gas exchange threshold values of cross-country skiers across training phases throughout a season. In total, 15 athletes who participate in international cross-country ski competitions voluntarily took part in this study. The athletes underwent incremental treadmill running tests at 3 different time points over a period of 1 year. The first measurements were obtained in July, during the first preparation period; the second measurements were obtained in October, during the second preparation period; and the third measurements were obtained in February, during the competition period. Body weight, body mass index (BMI), body fat (%), as well as VO 2max values and gas exchange threshold, measured using V-slope method during the incremental running tests, were assessed at all 3 time points. The collected data were analyzed using SPSS 20 package software. Significant differences between the measurements were assessed using Friedman's twoway variance analysis with a post hoc option. The athletes' body weights and BMI measurements at the third point were significantly lower compared with the results of the second measurement ( p <0.001). Moreover, the incremental running test time was significantly higher at the third measurement, compared with both the first ( p <0.05) and the second ( p <0.01) measurements. Similarly, the running speed during the test was significantly higher at the third measurement time point compared with the first measurement time point ( p <0.05). Body fat (%), time to reach the gas exchange threshold, running speed at the gas exchange threshold, VO 2max , amount of oxygen consumed at gas exchange threshold level (VO 2GET ), maximal heart rate (HR max ), and heart rate at gas exchange threshold level (HR GET ) values did not significantly differ between the measurement time points ( p >0.05). VO 2max and gas exchange threshold values recorded during the third measurements, the timing of which coincided with the competitive season of the cross-country skiers, did not significantly change, but their incremental running test time and running speed significantly increased while their body weight and BMI significantly decreased. These results indicate that the cross-country skiers developed a tolerance for high-intensity exercise and reached their highest level of athletic performance during the competitive season.

Improving Running Economy by Transitioning to Minimalist Footwear: A Randomised Controlled Trial.

PubMed

Lindlein, K; Zech, A; Zoch, A; Braumann, K-M; Hollander, K

2018-05-25

Ongoing debates about benefits and risks of barefoot- and minimally-shod running have, to date, revealed no conclusive findings for long-term effects on physical performance. The purpose of this study was to examine the effects of an 8-week transition to minimalist footwear (MFW) on running economy (RE). Randomised controlled trial. Thirty-two male, habitually-shod runners were assigned randomly to an 8-week training intervention either in minimalist (=intervention group) or conventional running shoes (=control group). The intervention consisted of a gradual increase in use of the new footwear by 5% of the individual weekly distance. Before and after the intervention, a VO 2 max test was followed by a submaximal RE test at 70% and 80% of vVO 2 max in both shoe conditions 7days later. RE was measured at the submaximal tests and expressed as caloric unit cost (kcalkg -1 km -1 ) and oxygen consumption (mlkg -1 km -1 ). RE improved in the intervention group over time compared to the control group with small to moderate effect sizes (ES) in both shoe conditions: Effects on RE (kcalkg -1 km -1 ) in conventional running shoes: ES vVO 2 70%: 0.68 (95% CI: -0.14 to 1.51), ES vVO 2 80%: 0.78 (95% CI: 0-1.56). In minimalist footwear: ES vVO 2 70%: 0.3 (95% CI: -0.54 to 1.14), ES vVO 2 80%: 0.42 (95% CI: -0.41 to 1.25). These effects were not statistically significant (p>0.05). The repeated-measures ANOVA also showed no group by time interactions for all submaximal RE testing conditions (p>0.05). Although not reaching statistical significance, training in MFW compared to CRS resulted in small to moderate improvements in RE. Copyright © 2018 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

The effect of sprinting after each set of heavy resistance training on the running speed and jumping performance of young basketball players.

PubMed

Tsimahidis, Konstantinos; Galazoulas, Christos; Skoufas, Dimitrios; Papaiakovou, Georgios; Bassa, Eleni; Patikas, Dimitrios; Kotzamanidis, Christos

2010-08-01

The purpose of this study was to investigate the effect of a 10-week heavy resistance combined with a running training program on the strength, running speed (RS), and vertical jump performance of young basketball players. Twenty-six junior basketball players were equally divided in 2 groups. The control (CON) group performed only technical preparation and the group that followed the combined training program (CTP) performed additionally 5 sets of 8-5 repetition maximum (RM) half squat with 1 30-m sprint after each set. The evaluation took place before training and after the 5th and 10th weeks of training. Apart from the 1RM half squat test, the 10- and 30-m running time was measured using photocells and the jump height (squat, countermovement jump, and drop jump) was estimated taking into account the flight time. The 1RM increased by 30.3 +/- 1.5% at the 10th week of training for the CTP group (p < 0.05), whereas the CON group showed no significant increase (1.1 +/- 1.6%, p > 0.05). In general, all measured parameters showed a statistically significant increase after the 5th and 10th weeks (p < 0.05), in contrast to the CON group (p > 0.05). This suggests that the applied CTP is beneficial for the strength, RS, and jump height of young basketball players. The observed adaptations in the CTP group could be attributed to learning factors and to a more optimal transfer of the strength gain to running and jumping performance.

A Laboratory Test for the Examination of Alactic Running Performance

PubMed Central

Kibele, Armin; Behm, David

2005-01-01

A new testing procedure is introduced to evaluate the alactic running performance in a 10s sprint task with near-maximal movement velocity. The test is performed on a motor-equipped treadmill with inverted polarity that increases mechanical resistance instead of driving the treadmill belt. As a result, a horizontal force has to be exerted against the treadmill surface in order to overcome the resistant force of the engine and to move the surface in a backward direction. For this task, subjects lean with their hands towards the front safety barrier of the treadmill railing with a slightly inclined body posture. The required skill resembles the pushing movement of bobsleigh pilots at the start of a race. Subjects are asked to overcome this mechanical resistance and to cover as much distance as possible within a time period of 10 seconds. Fifteen male students (age: 27.7 ± 4.1 years, body height: 1.82 ± 0.46 m, body mass: 78.3 ± 6.7 kg) participated in a study. As the resistance force was set to 134 N, subjects ran 35.4 ± 2.6 m on the average corresponding to a mean running velocity of 3.52 ± 0.25 m·s-1. The validity of the new test was examined by statistical inference with various measures related to alactic performance including a metabolic equivalent to estimate alactic capacity (2892 ± 525 mL O2), an estimate for the oxygen debt (2662 ± 315 ml), the step test by Margaria to estimate alactic energy flow (1691 ± 171 W), and a test to measure the maximal strength in the leg extensor muscles (2304 ± 351 N). The statistical evaluation showed that the new test is in good agreement with the theoretical assumptions for alactic performance. Significant correlation coefficients were found between the test criteria and the measures for alactic capacity (r = 0.79, p < 0.01) as well as alactic power (r = 0.77, p < 0.01). The testing procedure is easy to administer and it is best suited to evaluate the alactic capacity for bobsleigh pilots as well as for any other running discipline. Key Points New testing procedure for the evaluation of alactic running performance. 10s treadmill sprint task with near-maximal movement velocity similar to a bob sleigh start. Treadmill motor is used with inverted polarity to establish mechanical resistance rather than acceleration. Highly significant correlations found between test criteria and alactic performance measures. PMID:24501570

Individual Responses to a Barefoot Running Program: Insight Into Risk of Injury.

PubMed

Tam, Nicholas; Tucker, Ross; Astephen Wilson, Janie L

2016-03-01

Barefoot running is of popular interest because of its alleged benefits for runners, including reduced injury risk and increased economy of running. There is a dearth in understanding whether all runners can gain the proposed benefits of barefoot running and how barefoot running may affect long-term injury risk. The purpose of this study was to determine whether runners can achieve the proposed favorable kinematic changes and reduction in loading rate after a progressive training program that included barefoot running. It was hypothesized that not all individuals would experience a decrease in initial loading rate facilitated by increased ankle plantar flexion after a progressive barefoot running program; it was further hypothesized that relationships exist between changes in initial loading rate and sagittal ankle angle. Descriptive laboratory study. A total of 26 habitually shod runners completed an 8-week, progressively introduced barefoot running program. Pre- and postintervention barefoot and shod kinematics, electromyography, and ground-reaction force data of the lower limb were collected. Ankle and knee kinematics and kinetics, initial loading rates, spatiotemporal variables, muscle activity during preactivation, and ground contact were assessed in both conditions before and after the intervention. Individual responses were analyzed by separating runners into nonresponders, negative responders, and positive responders based on no change, increase, and decrease in barefoot initial loading rate, respectively. No biomechanical changes were found in the group after the intervention. However, condition differences did persist during both preactivation and ground contact. The positive-responder group had greater plantar flexion, increased biceps femoris and gluteus medius preactivation, and decreased rectus femoris muscle activity between testing periods. The negative responders landed in greater barefoot dorsiflexion after the intervention, and the nonresponders did not change. An overall change in ankle flexion angle was associated with a change in initial loading rate (r(2) = 0.345, P = .002) in the barefoot but not shod condition. Eight weeks of progressive barefoot running did not change overall group biomechanics, but subgroups of responders (25% of the entire group) were identified who had specific changes that reduced the initial loading rate. It appears that changes in initial loading rate are explained by changes in ankle flexion angle at initial ground contact. Uninstructed barefoot running training does not reduce initial loading rate in all runners transitioning from shod to barefoot conditions. Some factors have been identified that may assist sports medicine professionals in the evaluation and management of runners at risk of injury. Conscious instruction to runners may be required for them to acquire habitual barefoot running characteristics and to reduce risk of injury. © 2016 The Author(s).

DIRECT LIQUEFACTION PROOF OF CONCEPT

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The eighth bench scale test of POC program, Run PB-08, was successfully completed from August 8 to August 26, 1997. A total of five operating conditions were tested aiming at evaluating the reactivity of different pyrolysis oils in liquefaction of a Wyoming sub-bituminous coal (Black Thunder coal). For the first time, water soluble promoters were incorporated into the iron-based GelCat to improve the dispersion of the promoter metals in the feed blend. The concentration of the active metals, Mo and Fe, was 100 and 1000 ppm of moisture-free coal, respectively. Black Thunder coal used in this run was the samemore » batch as tested in HTI�s Run POC-02. Similar to Runs PB-01 through 7, this run employed two back mixed slurry reactors, an interstage gas/slurry separator and a direct-coupled hydrotreater. In addition to the hot vapor from the second stage separator, the first stage separator overhead liquid was also fed to the hydrotreater, which was packed with Criterion C-411 hydrotreating catalyst. Pyrolysis oil was produced off-line from a pyrolysis unit acquired from University of Wyoming. Solids rejection was achieved by purging out pressure filter solid. The recycle solvents consisted of O-6 separator bottoms and pressure filter liquid (PFL). The Run PB-08 proceeded very smoothly without any interruptions. Coal conversion consistently above 90W% was achieved. High resid conversion and distillate yield have been obtained from co-processing of coal and 343°C+ (650°F+) pyrolysis oil. Light gas (C 1-C 3 ) yield was minimized and hydrogen consumption was reduced due to the introduction of pyrolysis oil, compared with conventional coal-derived solvent. Catalytic activity was improved by incorporating a promoter metal into the iron-based GelCat. It seemed that lowering the first stage temperature to 435°C might increase the hydrogenation function of the promoter metal. In comparison with previous coal-waste coprocessing run (PB-06), significant improvements in the process performance were achieved due to catalyst modification and integration of pyrolysis technique into liquefaction.« less

Influences on the Test-Retest Reliability of Functional Connectivity MRI and its Relationship with Behavioral Utility.

PubMed

Noble, Stephanie; Spann, Marisa N; Tokoglu, Fuyuze; Shen, Xilin; Constable, R Todd; Scheinost, Dustin

2017-11-01

Best practices are currently being developed for the acquisition and processing of resting-state magnetic resonance imaging data used to estimate brain functional organization-or "functional connectivity." Standards have been proposed based on test-retest reliability, but open questions remain. These include how amount of data per subject influences whole-brain reliability, the influence of increasing runs versus sessions, the spatial distribution of reliability, the reliability of multivariate methods, and, crucially, how reliability maps onto prediction of behavior. We collected a dataset of 12 extensively sampled individuals (144 min data each across 2 identically configured scanners) to assess test-retest reliability of whole-brain connectivity within the generalizability theory framework. We used Human Connectome Project data to replicate these analyses and relate reliability to behavioral prediction. Overall, the historical 5-min scan produced poor reliability averaged across connections. Increasing the number of sessions was more beneficial than increasing runs. Reliability was lowest for subcortical connections and highest for within-network cortical connections. Multivariate reliability was greater than univariate. Finally, reliability could not be used to improve prediction; these findings are among the first to underscore this distinction for functional connectivity. A comprehensive understanding of test-retest reliability, including its limitations, supports the development of best practices in the field. © The Author 2017. Published by Oxford University Press.

Analysis of Elements of the Continuous Monitoring Program

DTIC Science & Technology

2009-12-01

reasons for differences in financial reporting between the CMP and BOR and provide COMNAVSURFOR the opportunity to increase financial reporting timeliness...accuracy, and completeness of the surface fleet. A methodology was developed to analyze financial reporting within the cruiser and frigate classes...the different groupings. A Beta Test was run on six ships for two months, which tested the recommended alternatives to financial reporting and

Twelve Weeks of Plyometric Training Improves Motor Performance of 7- to 9-Year-Old Boys Who Were Overweight/Obese: A Randomized Controlled Intervention.

PubMed

Nobre, Gabriela G; de Almeida, Marcelus B; Nobre, Isabele G; Dos Santos, Fernanda K; Brinco, Raphael A; Arruda-Lima, Thalison R; de-Vasconcelos, Kenya L; de-Lima, Jociellen G; Borba-Neto, Manoel E; Damasceno-Rodrigues, Emmanuel M; Santos-Silva, Steve M; Leandro, Carol G; Moura-Dos-Santos, Marcos A

2017-08-01

Nobre, GG, de Almeida, MB, Nobre, IG, dos Santos, FK, Brinco, RA, Arruda-Lima, TR, de-Vasconcelos, KL, de-Lima, JG, Borba-Neto, ME, Damasceno-Rodrigues, EM, Santos-Silva, SM, Leandro, CG, and Moura-dos-Santos, MA. Twelve weeks of plyometric training improves motor performance of 7- to 9-year-old boys who were overweight/obese: a randomized controlled intervention. J Strength Cond Res 31(8): 2091-2099, 2017-The prevalence of childhood overweight/obesity has increased, and physical training at school may to be effective to combat this scenario. We analyzed the effects of a protocol of plyometric training on body composition and motor performance of boys who were overweight/obese aged 7-9 years. The sample was randomly assigned into 2 groups: plyometric training group (T, n = 40) and control group (C, n = 19). Training consisted of 20 min·d (twice a week, during 12 weeks) of lower extremity plyometric exercise. Health-related physical fitness was measured by handgrip strength, standing long jump (SLJ), curl-ups, sit and reach, square test, running speed, and mile run test. Gross motor coordination was evaluated by means of the Körperkoordinations-test für Kinder (KTK) tests. Baseline and postintervention differences were investigated, and effect size was estimated through Cohen's d coefficient. Both groups showed increased body weight, height, and sitting height after intervention with a negligible effect size. Only T group showed increased fat-free mass (p = 0.011) compared with baseline values with small effect size. Plyometric training improved handgrip strength (d = 0.23), sit and reach (d = 0.18), curl-ups (d = 0.39), SLJ (d = 0.80), agility (d = 0.48), and time in the mile run test (d = 0.38). For gross motor coordination results, T group showed better performance in all tests after plyometric training with moderate/large effect size. Thus, 12 weeks of PT improved health-related physical fitness components and motor coordination acquisition of 7- to 9-year-old boys who were overweight/obese.

Advanced overlay: sampling and modeling for optimized run-to-run control

NASA Astrophysics Data System (ADS)

Subramany, Lokesh; Chung, WoongJae; Samudrala, Pavan; Gao, Haiyong; Aung, Nyan; Gomez, Juan Manuel; Gutjahr, Karsten; Park, DongSuk; Snow, Patrick; Garcia-Medina, Miguel; Yap, Lipkong; Demirer, Onur Nihat; Pierson, Bill; Robinson, John C.

2016-03-01

In recent years overlay (OVL) control schemes have become more complicated in order to meet the ever shrinking margins of advanced technology nodes. As a result, this brings up new challenges to be addressed for effective run-to- run OVL control. This work addresses two of these challenges by new advanced analysis techniques: (1) sampling optimization for run-to-run control and (2) bias-variance tradeoff in modeling. The first challenge in a high order OVL control strategy is to optimize the number of measurements and the locations on the wafer, so that the "sample plan" of measurements provides high quality information about the OVL signature on the wafer with acceptable metrology throughput. We solve this tradeoff between accuracy and throughput by using a smart sampling scheme which utilizes various design-based and data-based metrics to increase model accuracy and reduce model uncertainty while avoiding wafer to wafer and within wafer measurement noise caused by metrology, scanner or process. This sort of sampling scheme, combined with an advanced field by field extrapolated modeling algorithm helps to maximize model stability and minimize on product overlay (OPO). Second, the use of higher order overlay models means more degrees of freedom, which enables increased capability to correct for complicated overlay signatures, but also increases sensitivity to process or metrology induced noise. This is also known as the bias-variance trade-off. A high order model that minimizes the bias between the modeled and raw overlay signature on a single wafer will also have a higher variation from wafer to wafer or lot to lot, that is unless an advanced modeling approach is used. In this paper, we characterize the bias-variance trade off to find the optimal scheme. The sampling and modeling solutions proposed in this study are validated by advanced process control (APC) simulations to estimate run-to-run performance, lot-to-lot and wafer-to- wafer model term monitoring to estimate stability and ultimately high volume manufacturing tests to monitor OPO by densely measured OVL data.

Effects of Spontaneous Locomotion on the Cricket's Walking Response to a Wind Stimulus

NASA Astrophysics Data System (ADS)

Gras, Heribert; Bartels, Anke

Tethered walking crickets often respond to single wind puffs (50ms duration) directed from 45° left or right to the abdominal cerci with a short running bout of about 300ms, followed by normal locomotion. To test for an effect of the current behavioral state on the running response, we applied wind stimuli when the insect attained a predefined translatorial and/or rotatorial velocity during spontaneous walking. The latency, duration, and velocity profile of the running bout always proved to be constant, representing a reflexlike all-or-nothing reaction, while the probability of this response was low after even brief standing and increased with the forward speed of spontaneous walking at the moment of stimulation. In contrast, the current rotatorial speed did not affect the stimulus response.

Effects of a capacitive-resistive electric transfer therapy on physiological and biomechanical parameters in recreational runners: A randomized controlled crossover trial.

PubMed

Duñabeitia, Iratxe; Arrieta, Haritz; Torres-Unda, Jon; Gil, Javier; Santos-Concejero, Jordan; Gil, Susana M; Irazusta, Jon; Bidaurrazaga-Letona, Iraia

2018-05-26

This study compared the effects of a capacitive-resistive electric transfer therapy (Tecar) and passive rest on physiological and biomechanical parameters in recreational runners when performed shortly after an exhausting training session. Randomized controlled crossover trial. University biomechanical research laboratory. Fourteen trained male runners MAIN OUTCOME MEASURES: Physiological (running economy, oxygen uptake, respiratory exchange ratio, ventilation, heart rate, blood lactate concentration) and biomechanical (step length; stride angle, height, frequency, and contact time; swing time; contact phase; support phase; push-off phase) parameters were measured during two incremental treadmill running tests performed two days apart after an exhaustive training session. When running at 14 km/h and 16 km/h, the Tecar treatment group presented greater increases in stride length (p < 0.001), angle (p < 0.05) and height (p < 0.001) between the first and second tests than the control group and, accordingly, greater decreases in stride frequency (p < 0.05). Physiological parameters were similar between groups. The present study suggests that a Tecar therapy intervention enhances biomechanical parameters in recreational runners after an exhaustive training session more than passive rest, generating a more efficient running pattern without affecting selected physiological parameters. Copyright © 2018 Elsevier Ltd. All rights reserved.

Effects of the progressive walking-to-running technique on gait kinematics, ultrasound imaging, and motor function in spastic diplegic cerebral palsy - an experimenter-blind case study.

PubMed

Lee, Nam Gi; Jeong, Su Ji; You, Joshua Sung Hyun; Cho, Kang Hee; Lee, Tae Heon

2013-01-01

The purpose of this study was to investigate the effects of the progressive walking-to-running technique (PWRT) in a child with spastic diplegic cerebral palsy (CP). A single case study with pre-/post-test. An 11-year-old male, diagnosed with spastic diplegic CP. The PWRT was provided for 60 minutes a day, 2 times a week for 12 weeks. Gross motor function tests, ultrasound imaging, hand-held dynamometer, and the Vicon motion capture system were used to determine motor function, muscle size and strength, and gait kinematics. Gross motor function was improved after the intervention. The size of right and left rectus femoris and tibialis anterior muscles in their contracted states were enhanced by 1.36, 5.09, 83.74, and 54.37%, respectively. Associated muscle strength was also increased by 58.8, 30.8, 28.0, and 118.2% in both rectus femoris and tibialis anterior muscles. Left stride length, walking speed, maximal flexion-extension angular excursion of the hip joint were enhanced by 95.7, 87.8, and 100.4% after PWRT, respectively. Our novel walking-running training paradigm was effective for restoring gait and running ability in a child with spastic diplegic CP.

Finite element simulation of structural performance on flexible pavements with stabilized base/treated subbase materials under accelerated loading.

DOT National Transportation Integrated Search

2011-12-01

Accelerated pavement testing (APT) has been increasingly used by state highway agencies in recent years for evaluating pavement structures and/or materials. However, running an APT experiment is expensive. It requires costly accelerated loading devic...

Estrogen and voluntary exercise interact to attenuate stress-induced corticosterone release but not anxiety-like behaviors in female rats.

PubMed

Jones, Alexis B; Gupton, Rebecca; Curtis, Kathleen S

2016-09-15

The beneficial effects of physical exercise to reduce anxiety and depression and to alleviate stress are increasingly supported in research studies. The role of ovarian hormones in interactions between exercise and anxiety/stress has important implications for women's health, given that women are at increased risk of developing anxiety-related disorders, particularly during and after the menopausal transition. In these experiments, we tested the hypothesis that estrogen enhances the positive impact of exercise on stress responses by investigating the combined effects of exercise and estrogen on anxiety-like behaviors and stress hormone levels in female rats after an acute stressor. Ovariectomized female rats with or without estrogen were given access to running wheels for one or three days of voluntary running immediately after or two days prior to being subjected to restraint stress. We found that voluntary running was not effective at reducing anxiety-like behaviors, whether or not rats were subjected to restraint stress. In contrast, stress-induced elevations of stress hormone levels were attenuated by exercise experience in estrogen-treated rats, but were increased in rats without estrogen. These results suggest that voluntary exercise may be more effective at reducing stress hormone levels if estrogen is present. Additionally, exercise experience, or the distance run, may be important in reducing stress. Copyright © 2016 Elsevier B.V. All rights reserved.

You sneeze, you lose:: The impact of pollen exposure on cognitive performance during high-stakes high school exams.

PubMed

Bensnes, Simon Søbstad

2016-09-01

Pollen is known to cause allergic reactions and affect cognitive performance in around 20% of the population. Although pollen season peaks when students take high-stakes exams, the effect of pollen allergies on school performance has received nearly no attention from economists. Using a student fixed effects model and administrative Norwegian data, this paper finds that increasing the ambient pollen levels by one standard deviation at the mean leads to a 2.5% standard deviation decrease in test scores, with potentially larger effects for allergic students. There also appear to be longer-run effects. The findings imply that random increases in pollen counts reduce test scores for allergic students relative to their peers, who consequently will be at a disadvantage when competing for jobs or higher education. This paper contributes to the literature by illuminating the interplay between individual health and human capital accumulation, which in turn can impact long-run economic growth. Copyright © 2016 Elsevier B.V. All rights reserved.

Rethinking stereotype reliance. Understanding the connection between female candidates and gender stereotypes.

PubMed

Bauer, Nichole M

2013-01-01

Increasing numbers of female candidates are running for Congress in American national elections. Despite the rise in female candidates running for office, women are not significantly increasing their presence in the House and Senate. A much hypothesized influence over the electoral fates of female candidates is the role of gender stereotypes. However, political science scholars have struggled to pinpoint the effect of stereotypes on vote choice, if there is any effect. This essay compares the way social psychology and political science scholars theoretically, conceptually and empirically test for gender stereotype influence over evaluations of female candidates and politicians. Differences emerge in the theoretical assumptions made in the two disciplines, the types of measures used in research, and the empirical tests conducted to demonstrate the presence or absence of stereotypes in evaluations of women. The discussion explores how scholars studying female candidates and politicians can integrate insights from social psychology to clarify the role of stereotypes in candidate evaluation and choice.

Full-scale Wind-tunnel and Flight Tests of a Fairchild 22 Airplane Equipped with a Fowler Flap

NASA Technical Reports Server (NTRS)

Dearborn, C H; Soule, H A

1936-01-01

Full-scale wind-tunnel and flight tests were made of a Fairchild 22 airplane equipped with a Fowler flap to determine the effect of the flap on the performance and control characteristics of the airplane. In the wind-tunnel tests of the airplane with the horizontal tail surfaces removed, the flap was found to increase the maximum lift coefficient from 1.27 to 2.41. In the flight test, the flap was found to decrease the minimum speed from 58.8 to 44.4 miles per hour. The required take-off run to attain an altitude of 50 feet was reduced from 935 feet to 700 feet by the use of the flap, the minimum distance being obtained with five-sixths full deflection. The landing run from a height of 50 feet was reduced one-third. The longitudinal and directional control was adversely affected by the flap, indicating that the design of the tail surfaces is more critical with a flapped than a plain wing.

40 CFR 63.1546 - Performance testing.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 13 2012-07-01 2012-07-01 false Performance testing. 63.1546 Section... Emission Standards for Hazardous Air Pollutants for Primary Lead Smelting § 63.1546 Performance testing. (a... performance test shall consist of at least three runs. For each test run with Method 12 or Method 29, the...

History of United States Army physical fitness and physical readiness training.

PubMed

Knapik, Joseph J; East, Whitfield B

2014-01-01

This article traces the history of US Army physical fitness assessments from the first test developed for Cadets at the US Military Academy in 1858 through efforts to revise the current Army Physical Fitness Test (APFT). The first "Individual Efficiency Test" (1920) for all Soldiers consisted of a 100-yard run, running broad jump, wall climb, hand grenade throw, and obstacle course. The first scientific efforts involved testing of 400 Soldiers and a factor analysis of 25 individual test items. In 1944, this resulted in a 7-item test (pull-up, burpee, squat jump, push-up, man-carry, sit-up and 300-yard run) with a 100-point scoring system. In 1943, women were encouraged to take a "self-assessment" consisting of push-ups, bent knee sit-ups, wing lifts, squat thrusts, running, and a stork stand. In 1946, age-adjusted standards were introduced and in 1965 semiannual fitness assessments were mandated. The number of tests proliferated in the 1969-1973 period with 7 separate assessments. The current APFT consisting of push-ups, sit-ups, and a 2-mile run was introduced in 1980 and alternative tests for those with physical limitations in 1982. Current efforts to revise the assessment involve systematic literature reviews and validating the relationship between test items and common Soldiering tasks.

Defensive Swarm: An Agent Based Modeling Analysis

DTIC Science & Technology

2017-12-01

INITIAL ALGORITHM (SINGLE- RUN ) TESTING .........................43  1.  Patrol Algorithm—Passive...scalability are therefore quite important to modeling in this highly variable domain. One can force the software to run the gamut of options to see...changes in operating constructs or procedures. Additionally, modelers can run thousands of iterations testing the model under different circumstances

The Relationship between Field Tests of Anaerobic Power and 10-km Run Performance.

ERIC Educational Resources Information Center

Sinnett, Aaron M.; Berg, Kris; Latin, Richard W.; Noble, John M.

2001-01-01

Investigated the relationship between several field tests of anaerobic power (e.g., +various sprints, vertical jumps, and a plyometric leap) and distance running performance in trained adult male and female runners. Results indicate that anaerobic power is significantly related to distance running performance and may explain a meaningful…

The 1-mile walk test is a valid predictor of VO(2max) and is a reliable alternative fitness test to the 1.5-mile run in U.S. Air Force males.

PubMed

Weiglein, Laura; Herrick, Jeffery; Kirk, Stacie; Kirk, Erik P

2011-06-01

The purpose of this study was to assess the validity of the 1-mile walk (Rockport Walk Test) as a predictor of VO(2max) and determine whether the 1-mile walk is a reliable alternative to the 1.5-mile run in moderately fit to highly fit U.S. Air Force males. Twenty-four (33.0 +/- 1.5 years) males completed a maximal treadmill VO(2max) (50.3 +/- 1.4 mL/ kg/min), 1-mile walk, and 1.5-mile run. For the 1-mile walk, there were no significant differences between measured and predicted VO(2max) (p = 0.177, r = 0.817). There were no significant differences (p = 0.573) between points scored in the Air Force Fitness Test for the 1-mile walk and 1.5-mile run tests. In conclusion, the 1-mile walk test is a valid predictor of VO(2max) and can be used as an alternative fitness test to the 1.5-mile run in assessing cardiovascular fitness in Air Force males.

Physiological and Biomechanical Responses of Highly Trained Distance Runners to Lower-Body Positive Pressure Treadmill Running.

PubMed

Barnes, Kyle R; Janecke, Jessica N

2017-11-21

As a way to train at faster running speeds, add training volume, prevent injury, or rehabilitate after an injury, lower-body positive pressure treadmills (LBPPT) have become increasingly commonplace among athletes. However, there are conflicting evidence and a paucity of data describing the physiological and biomechanical responses to LBPPT running in highly trained or elite caliber runners at the running speeds they habitually train at, which are considerably faster than those of recreational runners. Furthermore, data is lacking regarding female runners' responses to LBPPT running. Therefore, this study was designed to evaluate the physiological and biomechanical responses to LBPPT running in highly trained male and female distance runners. Fifteen highly trained distance runners (seven male; eight female) completed a single running test composed of 4 × 9-min interval series at fixed percentages of body weight ranging from 0 to 30% body weight support (BWS) in 10% increments on LBPPT. The first interval was always conducted at 0% BWS; thereafter, intervals at 10, 20, and 30% BWS were conducted in random order. Each interval consisted of three stages of 3 min each, at velocities of 14.5, 16.1, and 17.7 km·h -1 for men and 12.9, 14.5, and 16.1 km·h -1 for women. Expired gases, ventilation, breathing frequency, heart rate (HR), rating of perceived exertion (RPE), and stride characteristics were measured during each running speed and BWS. Male and female runners had similar physiological and biomechanical responses to running on LBPPT. Increasing BWS increased stride length (p < 0.02) and flight duration (p < 0.01) and decreased stride rate (p < 0.01) and contact time (p < 0.01) in small-large magnitudes. There was a large attenuation of oxygen consumption (VO 2 ) relative to BWS (p < 0.001), while there were trivial-moderate reductions in respiratory exchange ratio, minute ventilation, and respiratory frequency (p > 0.05), and small-large effects on HR and RPE (p < 0.01). There were trivial-small differences in V E , respiratory frequency, HR, and RPE for a given VO 2 across various BWS (p > 0.05). The results indicate the male and female distance runners have similar physiological and biomechanical responses to LBPPT running. Overall, the biomechanical changes during LBPPT running all contributed to less metabolic cost and corresponding physiological changes.

Running Promotes Wakefulness and Increases Cataplexy in Orexin Knockout Mice

PubMed Central

España, Rodrigo A.; McCormack, Sarah L.; Mochizuki, Takatoshi; Scammell, Thomas E.

2007-01-01

Study Objective: People with narcolepsy and mice lacking orexin/hypocretin have disrupted sleep/wake behavior and reduced physical activity. Our objective was to identify physiologic mechanisms through which orexin deficiency reduces locomotor activity. Design: We examined spontaneous wheel running activity and its relationship to sleep/wake behavior in wild type (WT) and orexin knockout (KO) mice. Additionally, given that physical activity promotes alertness, we also studied whether orexin deficiency reduces the wake-promoting effects of exercise. Measurements and Results: Orexin KO mice ran 42% less than WT mice. Their ability to run appeared normal as they initiated running as often as WT mice and ran at normal speeds. However, their running bouts were considerably shorter, and they often had cataplexy or quick transitions into sleep after running. Wheel running increased the total amount of wakefulness in WT and orexin KO mice similarly, however, KO mice continued to have moderately fragmented sleep/wake behavior. Wheel running also doubled the amount of cataplexy by increasing the probability of transitioning into cataplexy. Conclusions: Orexin KO mice run significantly less than normal, likely due to sleepiness, imminent cataplexy, or a reduced motivation to run. Orexin is not required for the wake-promoting effects of wheel running given that both WT and KO mice had similar increases in wakefulness with running wheels. In addition, the clear increase in cataplexy with wheel running suggests the possibility that positive emotions or reward can trigger murine cataplexy, similar to that seen in people and dogs with narcolepsy. Citation: España RA; McCormack SL; Mochizuki T; Scammell TE. Running promotes wakefulness and increases cataplexy in orexin knockout mice. SLEEP 2007;30(11):1417-1425. PMID:18041476

Load-carriage distance run and push-ups tests: no body mass bias and occupationally relevant.

PubMed

Vanderburgh, Paul M; Mickley, Nicholas S; Anloague, Philip A

2011-09-01

Recent research has demonstrated body mass (M) bias in military physical fitness tests favoring lighter, not just leaner, service members. Mathematical modeling predicts that a distance run carrying a backpack of 30 lbs would eliminate M-bias. The purpose of this study was to empirically test this prediction for the U.S. Army push-ups and 2-mile run tests. Two tests were performed for both events for each of 56 university Reserve Officer Training Corps male cadets: with (loaded) and without backpack (unloaded). Results indicated significant M-bias in the unloaded and no M-bias in the loaded condition for both events. Allometrically scaled scores for both events were worse in the loaded vs. unloaded conditions, supporting a hypothesis not previously tested. The loaded push-ups and 2-mile run appear to remove M-bias and are probably more occupationally relevant as military personnel are often expected to carry external loads.

Tactical Vehicle Climate Control Testing

DTIC Science & Technology

2017-03-31

MIL-STD-810G CN1. The greatest care must be taken to monitor this parameter during periods where the vehicle engine is running while in the chamber...a drain plug, wire pass-through, or the gunner’s hatch that can remain closed throughout testing to prevent damaging the cables. Avoid running ...drain plug, wire pass-through, or the gunner’s hatch, that can remain closed throughout testing to prevent damaging the cables. Avoid running cables

As-Run Physics Analysis for the UCSB-1 Experiment in the Advanced Test Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nielsen, Joseph Wayne

2015-09-01

The University of California Santa Barbara (UCSB) -1 experiment was irradiated in the A-10 position of the ATR. The experiment was irradiated during cycles 145A, 145B, 146A, and 146B. Capsule 6A was removed from the test train following Cycle 145A and replaced with Capsule 6B. This report documents the as-run physics analysis in support of Post-Irradiation Examination (PIE) of the test. This report documents the as-run fluence and displacements per atom (DPA) for each capsule of the experiment based on as-run operating history of the ATR. Average as-run heating rates for each capsule are also presented in this report tomore » support the thermal analysis.« less

On-board measurement of particle numbers and their size distribution from a light-duty diesel vehicle: Influences of VSP and altitude.

PubMed

Liu, Jia; Ge, Yunshan; Wang, Xin; Hao, Lijun; Tan, Jianwei; Peng, Zihang; Zhang, Chuanzhen; Gong, Huiming; Huang, Ying

2017-07-01

In this study, the particle size-resolved distribution from a China-3 certificated light-duty diesel vehicle was measured by using a portable emission measurement system (PEMS). In order to examine the influences of vehicle specific power (VSP) and high-altitude operation, measurements were conducted at 8 constant speeds, which ranged from 10 to 80km/hr at 10km/hr intervals, and two different high altitudes, namely 2200 and 3200m. The results demonstrated that the numbers of particles in all size ranges decreased significantly as VSP increased when the test vehicle was running at lower speeds (<20km/hr), while at a moderate speed (between 30 and 60km/hr), the particle number was statistically insensitive to increase VSP. Under high-speed cruising conditions, the numbers of ultrafine particles and PM 2.5 were insensitive to changes in VSP, but the numbers of nanoparticles and PM 10 surged considerably. An increase in the operational altitude of the test vehicle resulted in increased particle number emissions at low and high driving speeds; however, particle numbers obtained at moderate speeds decreased as altitude rose. When the test vehicle was running at moderate speeds, particle numbers measured at the two altitudes were very close, except for comparatively higher number concentrations of nanoparticles measured at 2200m. Copyright © 2017. Published by Elsevier B.V.

The Effects of a Periodized vs. Traditional Military Training Program on 2-Mile Run Performance During the Army Physical Fitness Test (APFT).

PubMed

Stone, Brandon L; Heishman, Aaron D; Campbell, Jay A

2017-07-31

The purpose of this study was to compare the effects of an experimental versus traditional military run training on 2-mile run ability in Army Reserve Officer Training Corps (ROTC) cadets. Fifty college-aged cadets were randomly placed into two groups and trained for four weeks with either an experimental running program (EXP, n=22) comprised of RPE intensity-specific, energy system based intervals or with traditional military running program (TRA, n=28) utilizing a crossover study design. A 2-mile run assessment was performed just prior to the start, at the end of the first 4 weeks, and again after the second 4 weeks of training following crossover. The EXP program significantly decreased 2-mile run times (961.3s ± 155.8s to 943.4 ± 140.2s, P=0.012, baseline to post 1) while the TRA group experienced a significant increase in run times (901.0 ± 79.2s vs. 913.9 ± 82.9s) over the same training period. There was a moderate effect size (d = 0.61, P=0.07) for the experimental run program to "reverse" the adverse effects of the traditional program within the 4-week training period (post 1 to post 2) following treatment crossover. Thus, for short-term training of military personnel, RPE intensity specific running program comprised of aerobic and anaerobic system development can enhance 2-mile run performance superior of a traditional program while reducing training volume (60 min per session vs. 43.2 min per session, respectively). Future research should extend the training period to determine efficacy of this training approach for long term improvement of aerobic capacity and possible reduction of musculoskeletal injury.

Running increases ethanol preference.

PubMed

Werme, Martin; Lindholm, Sara; Thorén, Peter; Franck, Johan; Brené, Stefan

2002-07-18

Wheel running performed by rats is reinforcing, rewarding and possibly addictive. In this study we analyzed if wheel running could affect ethanol preference. Lewis rats, known to be both addiction-prone and to develop an excessive wheel running behavior, were given access to ethanol in a two-bottle free-choice paradigm. The animals reached a high and stable ethanol intake after 5 weeks. In the next phase, rats were subjected to ethanol withdrawal for 1, 2 or 4 weeks with or without access to running wheels. Finally animals were again given access to ethanol in the same two-bottle free-choice paradigm, combined with access to running wheels. The rats that ran in running wheels during 1 or 2, but not 4, weeks of ethanol withdrawal increased both ethanol intake and preference as compared with the control group that did not have access to the wheels. Previous studies have demonstrated that low doses of morphine increases ethanol preference. Here we show that also running potentiates ethanol intake and preference. Thus, running which shares many of the reinforcing properties with addictive drugs appears to potentiate rats to an increased preference for ethanol. Our results describe a behavioral interaction where running increases ethanol consumption.

An indirect continuous running multistage field test: the Université de Montréal track test.

PubMed

Léger, L; Boucher, R

1980-06-01

The object of this study was to report on the validity and reliability of the Université de Montréal Track Test (UM-TT). The UM-TT is a continuous maximal indirect multistage running field test based on the energy cost of running. The first stage is set at a walking speed that requires 5 Mets; thereafter the speed is increased by 1 Met every two minutes. In order to assess the validity of the UM-TT, 25 subjects, 24.4 +/- 2.8 years old (X +/- SD) had their VO2max predicted with the UM-TT and measured directly with a running multistage treadmill test. Averages (+/- SD) were not significantly different (61.5 +/- 10.6 and 61.4 +/- 10.9 ml O2 . kg-1 . min-1, respectively), other statistics being r = 0.96, delta = 0.09 +/- 2.90 ml O2 . kg-1 . min-1 and Syx = 2.81 ml O2 . kg-1 . min-1. Seven males, 20.6 +/- 1.0 years old, had also their VO2max measured directly during the UM-TT. Comparison of predicted and directly measured VO2max yielded similar results: 70.0 +/- 4.5 and 70.7 +/- 6.0 ml O2 . kg-1 . min-1, respectively with r = 0.66, delta = 0.67 +/- 4.53 and Syx = 3.71. Reliability of the UM-TT was assessed by repeating the test twice on 60 subjects (49 males and 11 females; 39 subjects below 30 years old and 21, above; and 30 subjects below and above 15 Mets). Results were as follows: X +/- SD = 54.1 +/- 8.2 and 54.2 +/- 8.5, r = 0.97, delta 0.11 +/- 1.92, and Syx = 1.92. Similar reliability trends were observed for each one of the subgroups of subjects. It is concluded that the UM-TT is valid and reliable to estimate the VO2max of trained and untrained young and middle-age males and females.

Running Performance of a Pinning-Type Superconducting Magnetic Levitation Guide

NASA Astrophysics Data System (ADS)

Okano, M.; Iwamoto, T.; Furuse, M.; Fuchino, S.; Ishii, I.

2006-06-01

A pinning-type superconducting magnetic levitation guide with bulk high-Tc superconductors was studied for use as a goods transportation system, an energy storage system, etc. A superconducting magnetic levitation running test apparatus with a circular track of ca. 38 m length, 12 m diameter, which comprises the magnetic rail constituted by Nd-B-Fe rare-earth permanent magnets and steel plates, was manufactured to examine loss and high-speed performance of the magnetic levitation guide. Running tests were conducted in air. These tests clarify that a vehicle supported by a superconducting magnetic levitation guide runs stably at speeds greater than 42 km/h above the circular track.

Three essays in energy consumption: Time series analyses

NASA Astrophysics Data System (ADS)

Ahn, Hee Bai

1997-10-01

Firstly, this dissertation investigates that which demand specification is an appropriate model for long-run energy demand between the conventional demand specification and the limited demand specification. In order to determine the components of a stable long-run demand for different sectors of the energy industry, I perform cointegration tests by using the Johansen test procedure. First, I test the conventional demand specification including prices and income as components. Second, I test a limited demand specification only income as a component. The reason for performing these tests is that we can determine that which demand specification is a good long-run predictor of energy consumption between the two demand specifications by using the cointegration tests. Secondly, for the purpose of planning and forecasting energy demand in case of cointegrated system, long-run elasticities are of particular interest. To retrieve the optimal level of energy demand in case of price shock, we need long-run elasticities rather than short-run elasticities. The energy demand study provides valuable information to the energy policy makers who are concerned about the long-run impact of taxes and tariffs. A long-run price elasticity is a primary barometer of the substitution effect between energy and non-energy inputs and long-run income elasticity is an important factor since we can measure the energy demand growing slowly or fast than in the past depending on the magnitude of long-run elasticity. The one other problem in estimating the total energy demand is that there exists an aggregation bias stemming from the process of summation in four different energy types for the total aggregation prices and total aggregation energy consumption. In order to measure the aggregation bias between the Btu aggregation method and the Divisia Index method, i.e., which methodology has less aggregation bias in the long-run, I compare the two estimation results with calculated results estimated on a disaggregated basis. Thus, we can confirm whether or not the theoretically superior methodology has less aggregation bias in empirical estimation. Thirdly, I investigate the causal relationships between energy use and GDP. In order to detect causal relationships both in the long-run and in the short-run, the VECM (Vector Error Correction Model) can be used if there exists cointegration relationships among the variables. I detect the causal effects between energy use and GDP by estimating the VECM based on the multivariate production function including the labor and capital variables.

Static Stretching Alters Neuromuscular Function and Pacing Strategy, but Not Performance during a 3-Km Running Time-Trial

PubMed Central

Damasceno, Mayara V.; Duarte, Marcos; Pasqua, Leonardo A.; Lima-Silva, Adriano E.; MacIntosh, Brian R.; Bertuzzi, Rômulo

2014-01-01

Purpose Previous studies report that static stretching (SS) impairs running economy. Assuming that pacing strategy relies on rate of energy use, this study aimed to determine whether SS would modify pacing strategy and performance in a 3-km running time-trial. Methods Eleven recreational distance runners performed a) a constant-speed running test without previous SS and a maximal incremental treadmill test; b) an anthropometric assessment and a constant-speed running test with previous SS; c) a 3-km time-trial familiarization on an outdoor 400-m track; d and e) two 3-km time-trials, one with SS (experimental situation) and another without (control situation) previous static stretching. The order of the sessions d and e were randomized in a counterbalanced fashion. Sit-and-reach and drop jump tests were performed before the 3-km running time-trial in the control situation and before and after stretching exercises in the SS. Running economy, stride parameters, and electromyographic activity (EMG) of vastus medialis (VM), biceps femoris (BF) and gastrocnemius medialis (GA) were measured during the constant-speed tests. Results The overall running time did not change with condition (SS 11:35±00:31 s; control 11:28±00:41 s, p = 0.304), but the first 100 m was completed at a significantly lower velocity after SS. Surprisingly, SS did not modify the running economy, but the iEMG for the BF (+22.6%, p = 0.031), stride duration (+2.1%, p = 0.053) and range of motion (+11.1%, p = 0.0001) were significantly modified. Drop jump height decreased following SS (−9.2%, p = 0.001). Conclusion Static stretch impaired neuromuscular function, resulting in a slow start during a 3-km running time-trial, thus demonstrating the fundamental role of the neuromuscular system in the self-selected speed during the initial phase of the race. PMID:24905918

Running promotes wakefulness and increases cataplexy in orexin knockout mice.

PubMed

España, Rodrigo A; McCormack, Sarah L; Mochizuki, Takatoshi; Scammell, Thomas E

2007-11-01

People with narcolepsy and mice lacking orexin/hypocretin have disrupted sleep/wake behavior and reduced physical activity. Our objective was to identify physiologic mechanisms through which orexin deficiency reduces locomotor activity. We examined spontaneous wheel running activity and its relationship to sleep/wake behavior in wild type (WT) and orexin knockout (KO) mice. Additionally, given that physical activity promotes alertness, we also studied whether orexin deficiency reduces the wake-promoting effects of exercise. Orexin KO mice ran 42% less than WT mice. Their ability to run appeared normal as they initiated running as often as WT mice and ran at normal speeds. However, their running bouts were considerably shorter, and they often had cataplexy or quick transitions into sleep after running. Wheel running increased the total amount of wakefulness in WT and orexin KO mice similarly, however, KO mice continued to have moderately fragmented sleep/wake behavior. Wheel running also doubled the amount of cataplexy by increasing the probability of transitioning into cataplexy. Orexin KO mice run significantly less than normal, likely due to sleepiness, imminent cataplexy, or a reduced motivation to run. Orexin is not required for the wake-promoting effects of wheel running given that both WT and KO mice had similar increases in wakefulness with running wheels. In addition, the clear increase in cataplexy with wheel running suggests the possibility that positive emotions or reward can trigger murine cataplexy, similar to that seen in people and dogs with narcolepsy.

Common Leg Injuries of Long-Distance Runners

PubMed Central

Gallo, Robert A.; Plakke, Michael; Silvis, Matthew L.

2012-01-01

Context Long-distance running (greater than 3000 m) is often recommended to maintain a healthy lifestyle. Running injury rates increase significantly when weekly mileage extends beyond 40 miles cumulatively. With the development of running analysis and other diagnostic tests, injuries to the leg secondary to bone, musculotendinous, and vascular causes can be diagnosed and successfully managed. Evidence Acquisition Searches used the terms running, injuries, lower extremity, leg, medial tibial stress syndrome, compartment syndrome, stress fractures, popliteal artery entrapment, gastrocnemius soleus tears, and Achilles tendinopathy. Sources included Medline, Google Scholar, and Ovid from 1970 through January 2012. Results Tibial stress fractures and medial tibial stress syndrome can sometimes be prevented and/or treated by correcting biomechanical abnormalities. Exertional compartment syndrome and popliteal artery entrapment syndrome are caused by anatomic abnormalities and are difficult to treat without surgical correction. Conclusion Leg pain due to bone, musculotendinous, and vascular causes is common among long-distance runners. Knowledge of the underlying biomechanical and/or anatomic abnormality is necessary to successfully treat these conditions. PMID:24179587

40 CFR 63.1546 - Performance testing.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Performance testing. 63.1546 Section 63... Emission Standards for Hazardous Air Pollutants for Primary Lead Smelting § 63.1546 Performance testing. (a... performance test shall consist of at least three runs. For each test run with Method 12 or Method 29, the...

Voluntary Running Exercise-Mediated Enhanced Neurogenesis Does Not Obliterate Retrograde Spatial Memory.

PubMed

Kodali, Maheedhar; Megahed, Tarick; Mishra, Vikas; Shuai, Bing; Hattiangady, Bharathi; Shetty, Ashok K

2016-08-03

Running exercise (RE) improves cognition, formation of anterograde memories, and mood, alongside enhancing hippocampal neurogenesis. A previous investigation in a mouse model showed that RE-induced increased neurogenesis erases retrograde memory (Akers et al., 2014). However, it is unknown whether RE-induced forgetting is common to all species. We ascertained whether voluntary RE-induced enhanced neurogenesis interferes with the recall of spatial memory in rats. Young rats assigned to either sedentary (SED) or running exercise (RE) groups were first subjected to eight learning sessions in a water maze. A probe test (PT) conducted 24 h after the final training session confirmed that animals in either group had a similar ability for the recall of short-term memory. Following this, rats in the RE group were housed in larger cages fitted with running wheels, whereas rats in the SED group remained in standard cages. Animals in the RE group ran an average of 78 km in 4 weeks. A second PT performed 4 weeks after the first PT revealed comparable ability for memory recall between animals in the RE and SED groups, which was evidenced through multiple measures of memory retrieval function. The RE group displayed a 1.5- to 2.1-fold higher hippocampal neurogenesis than SED rats. Additionally, both moderate and brisk RE did not interfere with the recall of memory, although increasing amounts of RE proportionally enhanced neurogenesis. In conclusion, RE does not impair memory recall ability in a rat model despite substantially increasing neurogenesis. Running exercise (RE) improves new memory formation along with an increased neurogenesis in the hippocampus. In view of a recent study showing that RE-mediated increased hippocampal neurogenesis promotes forgetfulness in a mouse model, we ascertained whether a similar adverse phenomenon exists in a rat model. Memory recall ability examined 4 weeks after learning confirmed that animals that had run a mean of 78 km and displayed a 1.5- to 2.1-fold increase in hippocampal neurogenesis demonstrated similar proficiency for memory recall as animals that had remained sedentary. Furthermore, both moderate and brisk RE did not interfere with memory recall, although increasing amounts of RE proportionally enhanced neurogenesis, implying that RE has no adverse effects on memory recall. Copyright © 2016 the authors 0270-6474/16/368112-11$15.00/0.

NDIA 2018 IM and EM Technology Symposium: Innovative Insensitive Munition Solutions for Enhanced Warfighter Effectiveness

DTIC Science & Technology

2018-04-26

decomposition of explosives, test materials and their mixtures. A DSC for each individual explosive, test material and mixture shall be run in duplicate... run in duplicate • Explosives and test materials are mixed in a 1:1 (w/w) ratio • Samples are heated at a rate of 5°C/min from room temperature to...warrants it. If a reaction occurs in ten trials, the load is reduced until there are no reactions observed in ten trials. The ESD test was run per a

Is the COL5A1 rs12722 gene polymorphism associated with running economy?

PubMed

Bertuzzi, Rômulo; Pasqua, Leonardo A; Bueno, Salomão; Lima-Silva, Adriano Eduardo; Matsuda, Monique; Marquezini, Monica; Saldiva, Paulo H

2014-01-01

The COL5A1 rs12722 polymorphism is considered to be a novel genetic marker for endurance running performance. It has been postulated that COL5A1 rs12722 may influence the elasticity of tendons and the energetic cost of running. To date, there are no experimental data in the literature supporting the relationship between range of motion, running economy, and the COL5A1 rs12722 gene polymorphism. Therefore, the main purpose of the current study was to analyze the influence of the COL5A1rs12722 polymorphism on running economy and range of motion. One hundred and fifty (n = 150) physically active young men performed the following tests: a) a maximal incremental treadmill test, b) two constant-speed running tests (10 km · h(-1)) and 12 km · h(-1)) to determine the running economy, and c) a sit-and-reach test to determine the range of motion. All of the subjects were genotyped for the COL5A1 rs12722 single-nucleotide polymorphism. The genotype frequencies were TT = 27.9%, CT = 55.8%, and CC = 16.3%. There were no significant differences between COL5A1 genotypes for running economy measured at 10 km · h(-1) (p = 0.232) and 12 km · h(-1) (p = 0.259). Similarly, there were no significant differences between COL5A1 genotypes for range of motion (p = 0.337). These findings suggest that the previous relationship reported between COL5A1 rs12722 genotypes and running endurance performance might not be mediated by the energetic cost of running.

Is the COL5A1 rs12722 Gene Polymorphism Associated with Running Economy?

PubMed Central

Bertuzzi, Rômulo; Pasqua, Leonardo A.; Bueno, Salomão; Lima-Silva, Adriano Eduardo; Matsuda, Monique; Marquezini, Monica; Saldiva, Paulo H.

2014-01-01

The COL5A1 rs12722 polymorphism is considered to be a novel genetic marker for endurance running performance. It has been postulated that COL5A1 rs12722 may influence the elasticity of tendons and the energetic cost of running. To date, there are no experimental data in the literature supporting the relationship between range of motion, running economy, and the COL5A1 rs12722 gene polymorphism. Therefore, the main purpose of the current study was to analyze the influence of the COL5A1rs12722 polymorphism on running economy and range of motion. One hundred and fifty (n = 150) physically active young men performed the following tests: a) a maximal incremental treadmill test, b) two constant-speed running tests (10 km•h−1 and 12 km•h−1) to determine the running economy, and c) a sit-and-reach test to determine the range of motion. All of the subjects were genotyped for the COL5A1 rs12722 single-nucleotide polymorphism. The genotype frequencies were TT = 27.9%, CT = 55.8%, and CC = 16.3%. There were no significant differences between COL5A1 genotypes for running economy measured at 10 km•h−1 (p = 0.232) and 12 km•h−1 (p = 0.259). Similarly, there were no significant differences between COL5A1 genotypes for range of motion (p = 0.337). These findings suggest that the previous relationship reported between COL5A1 rs12722 genotypes and running endurance performance might not be mediated by the energetic cost of running. PMID:25188268

Progression of mechanical properties during on-field sprint running after returning to sports from a hamstring muscle injury in soccer players.

PubMed

Mendiguchia, J; Samozino, P; Martinez-Ruiz, E; Brughelli, M; Schmikli, S; Morin, J-B; Mendez-Villanueva, A

2014-07-01

The objectives of this study were to examine the consequences of an acute hamstring injury on performance and mechanical properties of sprint-running at the time of returning to sports and after the subsequent ~2 months of regular soccer training after return. 28 semi-professional male soccer players, 14 with a recent history of unilateral hamstring injury and 14 without prior injury, participated in the study. All players performed two 50-m maximal sprints when cleared to return to play (Test 1), and 11 injured players performed the same sprint test about 2 months after returning to play (Test 2). Sprint performance (i. e., speed) was measured via a radar gun and used to derive linear horizontal force-velocity relationships from which the following variables obtained: theoretical maximal velocity (V(0)), horizontal force (F(H0)) and horizontal power (Pmax). Upon returning to sports the injured players were moderately slower compared to the uninjured players. F H0 and Pmax were also substantially lower in the injured players. At Test 2, the injured players showed a very likely increase in F(H0) and Pmax concomitant with improvements in early acceleration performance. Practitioners should consider assessing and training horizontal force production during sprint running after acute hamstring injuries in soccer players before they return to sports. © Georg Thieme Verlag KG Stuttgart · New York.

Comparison of Sprint and Run Times with Performance on the Wingate Anaerobic Test.

ERIC Educational Resources Information Center

Tharp, Gerald D.; And Others

1985-01-01

Male volunteers were studied to examine the relationship between the Wingate Anaerobic Test (WAnT) and sprint-run times and to determine the influence of age and weight. Results indicate the WAnT is a moderate predictor of dash and run times but becomes a stronger predictor when adjusted for body weight. (Author/MT)

14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

Code of Federal Regulations, 2014 CFR

2014-01-01

... for each test run. (iv) Aircraft configuration, including landing gear positions. (v) Airspeed in... runs at the takeoff, level flyovers, and approach conditions. The 90 percent confidence limit applies... limit for all valid test runs under section H36.111(d) of this appendix applies separately to the EPNdB...

Voluntary wheel running increases bile acid as well as cholesterol excretion and decreases atherosclerosis in hypercholesterolemic mice.

PubMed

Meissner, Maxi; Lombardo, Elisa; Havinga, Rick; Tietge, Uwe J F; Kuipers, Folkert; Groen, Albert K

2011-10-01

Regular physical activity decreases the risk for atherosclerosis but underlying mechanisms are not fully understood. We questioned whether voluntary wheel running provokes specific modulations in cholesterol turnover that translate into a decreased atherosclerotic burden in hypercholesterolemic mice. Male LDLR-deficient mice (8 weeks old) had either access to a voluntary running wheel for 12 weeks (RUN) or remained sedentary (CONTROL). Both groups were fed a western-type/high cholesterol diet. Running activity and food intake were recorded. At 12 weeks of intervention, feces, bile and plasma were collected to determine fecal, biliary and plasma parameters of cholesterol metabolism and plasma cytokines. Atherosclerotic lesion size was determined in the aortic root. RUN weighed less (∼13%) while food consumption was increased by 17% (p=0.004). Plasma cholesterol levels were decreased by 12% (p=0.035) and plasma levels of pro-atherogenic lipoproteins decreased in RUN compared to control. Running modulated cholesterol catabolism by enhancing cholesterol turnover: RUN displayed an increased biliary bile acid secretion (68%, p=0.007) and increased fecal bile acid (93%, p=0.009) and neutral sterol (33%, p=0.002) outputs compared to control indicating that reverse cholesterol transport was increased in RUN. Importantly, aortic lesion size was decreased by ∼33% in RUN (p=0.033). Voluntary wheel running reduces atherosclerotic burden in hypercholesterolemic mice. An increased cholesterol turnover, specifically its conversion into bile acids, may underlie the beneficial effect of voluntary exercise in mice. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

40 CFR 60.533 - Compliance and certification.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., including the complete test report and, for all test runs: Raw data sheets, laboratory technician notes... each test run in a certification test series, two photographs of the fuel load: One before and one... of blower motors and the fan blade size. (3) Any change in the materials used for the following...

40 CFR 60.533 - Compliance and certification.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., including the complete test report and, for all test runs: Raw data sheets, laboratory technician notes... each test run in a certification test series, two photographs of the fuel load: One before and one... of blower motors and the fan blade size. (3) Any change in the materials used for the following...

40 CFR 60.533 - Compliance and certification.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., including the complete test report and, for all test runs: Raw data sheets, laboratory technician notes... each test run in a certification test series, two photographs of the fuel load: One before and one... of blower motors and the fan blade size. (3) Any change in the materials used for the following...

40 CFR 60.533 - Compliance and certification.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., including the complete test report and, for all test runs: Raw data sheets, laboratory technician notes... each test run in a certification test series, two photographs of the fuel load: One before and one... of blower motors and the fan blade size. (3) Any change in the materials used for the following...

40 CFR 60.533 - Compliance and certification.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., including the complete test report and, for all test runs: Raw data sheets, laboratory technician notes... each test run in a certification test series, two photographs of the fuel load: One before and one... of blower motors and the fan blade size. (3) Any change in the materials used for the following...

The development and validation of the Closed-set Mandarin Sentence (CMS) test.

PubMed

Tao, Duo-Duo; Fu, Qian-Jie; Galvin, John J; Yu, Ya-Feng

2017-09-01

Matrix-styled sentence tests offer a closed-set paradigm that may be useful when evaluating speech intelligibility. Ideally, sentence test materials should reflect the distribution of phonemes within the target language. We developed and validated the Closed-set Mandarin Sentence (CMS) test to assess Mandarin speech intelligibility in noise. CMS test materials were selected to be familiar words and to represent the natural distribution of vowels, consonants, and lexical tones found in Mandarin Chinese. Ten key words in each of five categories (Name, Verb, Number, Color, and Fruit) were produced by a native Mandarin talker, resulting in a total of 50 words that could be combined to produce 100,000 unique sentences. Normative data were collected in 10 normal-hearing, adult Mandarin-speaking Chinese listeners using a closed-set test paradigm. Two test runs were conducted for each subject, and 20 sentences per run were randomly generated while ensuring that each word was presented only twice in each run. First, the level of the words in each category were adjusted to produce equal intelligibility in noise. Test-retest reliability for word-in-sentence recognition was excellent according to Cronbach's alpha (0.952). After the category level adjustments, speech reception thresholds (SRTs) for sentences in noise, defined as the signal-to-noise ratio (SNR) that produced 50% correct whole sentence recognition, were adaptively measured by adjusting the SNR according to the correctness of response. The mean SRT was -7.9 (SE=0.41) and -8.1 (SE=0.34) dB for runs 1 and 2, respectively. The mean standard deviation across runs was 0.93 dB, and paired t-tests showed no significant difference between runs 1 and 2 (p=0.74) despite random sentences being generated for each run and each subject. The results suggest that the CMS provides large stimulus set with which to repeatedly and reliably measure Mandarin-speaking listeners' speech understanding in noise using a closed-set paradigm.

DWPF SIMULANT CPC STUDIES FOR SB7B

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koopman, D.

2011-11-01

Lab-scale DWPF simulations of Sludge Batch 7b (SB7b) processing were performed. Testing was performed at the Savannah River National Laboratory - Aiken County Technology Laboratory (SRNL-ACTL). The primary goal of the simulations was to define a likely operating window for acid stoichiometry for the DWPF Sludge Receipt and Adjustment Tank (SRAT). In addition, the testing established conditions for the SRNL Shielded Cells qualification simulation of SB7b-Tank 40 blend, supported validation of the current glass redox model, and validated the coupled process flowsheet at the nominal acid stoichiometry. An acid window of 105-140% by the Koopman minimum acid (KMA) equation (107-142%more » DWPF Hsu equation) worked for the sludge-only flowsheet. Nitrite was present in the SRAT product for the 105% KMA run at 366 mg/kg, while SME cycle hydrogen reached 94% of the DWPF Slurry Mix Evaporator (SME) cycle limit in the 140% KMA run. The window was determined for sludge with added caustic (0.28M additional base, or roughly 12,000 gallons 50% NaOH to 820,000 gallons waste slurry). A suitable processing window appears to be 107-130% DWPF acid equation for sludge-only processing allowing some conservatism for the mapping of lab-scale simulant data to full-scale real waste processing including potentially non-conservative noble metal and mercury concentrations. This window should be usable with or without the addition of up to 7,000 gallons of caustic to the batch. The window could potentially be wider if caustic is not added to SB7b. It is recommended that DWPF begin processing SB7b at 115% stoichiometry using the current DWPF equation. The factor could be increased if necessary, but changes should be made with caution and in small increments. DWPF should not concentrate past 48 wt.% total solids in the SME cycle if moderate hydrogen generation is occurring simultaneously. The coupled flowsheet simulation made more hydrogen in the SRAT and SME cycles than the sludge-only run with the same acid stoichiometric factor. The slow acid addition in MCU seemed to alter the reactions that consumed the small excess acid present such that hydrogen generation was promoted relative to sludge-only processing. The coupled test reached higher wt.% total solids, and this likely contributed to the SME cycle hydrogen limit being exceeded at 110% KMA. It is clear from the trends in the SME processing GC data, however, that the frit slurry formic acid contributed to driving the hydrogen generation rate above the SME cycle limit. Hydrogen generation rates after the second frit addition generally exceeded those after the first frit addition. SRAT formate loss increased with increasing acid stoichiometry (15% to 35%). A substantial nitrate gain which was observed to have occurred after acid addition (and nitrite destruction) was reversed to a net nitrate loss in runs with higher acid stoichiometry (nitrate in SRAT product less than sum of sludge nitrate and added nitric acid). Increased ammonium ion formation was also indicated in the runs with nitrate loss. Oxalate loss on the order 20% was indicated in three of the four acid stoichiometry runs and in the coupled flowsheet run. The minimum acid stoichiometry run had no indicated loss. The losses were of the same order as the official analytical uncertainty of the oxalate concentration measurement, but were not randomly distributed about zero loss, so some actual loss was likely occurring. Based on the entire set of SB7b test data, it is recommended that DWPF avoid concentrating additional sludge solids in single SRAT batches to limit the concentrations of noble metals to SB7a processing levels (on a grams noble metal per SRAT batch basis). It is also recommended that DWPF drop the formic acid addition that accompanies the process frit 418 additions, since SME cycle data showed considerable catalytic activity for hydrogen generation from this additional acid (about 5% increase in stoichiometry occurred from the frit formic acid). Frit 418 also does not appear to need formic acid addition to prevent gel formation in the frit slurry. Simulant processing was successful using 100 ppm of 747 antifoam added prior to nitric acid instead of 200 ppm. This is a potential area for DWPF to cut antifoam usage in any future test program. An additional 100 ppm was added before formic acid addition. Foaming during formic acid addition was not observed. No build-up of oily or waxy material was observed in the off-gas equipment. Lab-scale mercury stripping behavior was similar to SB6 and SB7a. More mercury was unaccounted for as the acid stoichiometry increased.« less

CO2 emissions, real output, energy consumption, trade, urbanization and financial development: testing the EKC hypothesis for the USA.

PubMed

Dogan, Eyup; Turkekul, Berna

2016-01-01

This study aims to investigate the relationship between carbon dioxide (CO2) emissions, energy consumption, real output (GDP), the square of real output (GDP(2)), trade openness, urbanization, and financial development in the USA for the period 1960-2010. The bounds testing for cointegration indicates that the analyzed variables are cointegrated. In the long run, energy consumption and urbanization increase environmental degradation while financial development has no effect on it, and trade leads to environmental improvements. In addition, this study does not support the validity of the environmental Kuznets curve (EKC) hypothesis for the USA because real output leads to environmental improvements while GDP(2) increases the levels of gas emissions. The results from the Granger causality test show that there is bidirectional causality between CO2 and GDP, CO2 and energy consumption, CO2 and urbanization, GDP and urbanization, and GDP and trade openness while no causality is determined between CO2 and trade openness, and gas emissions and financial development. In addition, we have enough evidence to support one-way causality running from GDP to energy consumption, from financial development to output, and from urbanization to financial development. In light of the long-run estimates and the Granger causality analysis, the US government should take into account the importance of trade openness, urbanization, and financial development in controlling for the levels of GDP and pollution. Moreover, it should be noted that the development of efficient energy policies likely contributes to lower CO2 emissions without harming real output.

Cold-gas experiments to study the flow separation characteristics of a dual-bell nozzle during its transition modes

NASA Astrophysics Data System (ADS)

Verma, S. B.; Stark, R.; Nuerenberger-Genin, C.; Haidn, O.

2010-06-01

An experimental investigation has been carried out to study the effect of test environment on transition characteristics and the flow unsteadiness associated with the transition modes of a dual-bell nozzle. Cold-gas tests using gaseous nitrogen were carried out in (i) a horizontal test-rig with nozzle exhausting into atmospheric conditions and, (ii) a high altitude simulation chamber with nozzle operation under self-evacuation mode. Transient tests indicate that increasing δP 0/ δt (the rate of stagnation chamber pressure change) reduces the amplitude of pressure fluctuations of the separation shock at the wall inflection point. This is preferable from the viewpoint of lowering the possible risk of any structural failure during the transition mode. Sea-level tests show 15-17% decrease in the transition nozzle pressure ratio (NPR) during subsequent tests in a single run primarily due to frost formation in the nozzle extension up to the wall inflection location. Frost reduces the wall inflection angle and hence, the transition NPR. However, tests inside the altitude chamber show nearly constant NPR value during subsequent runs primarily due to decrease in back temperature with decrease in back pressure that prevents any frost formation.

ALICE HLT Run 2 performance overview.

NASA Astrophysics Data System (ADS)

Krzewicki, Mikolaj; Lindenstruth, Volker; ALICE Collaboration

2017-10-01

For the LHC Run 2 the ALICE HLT architecture was consolidated to comply with the upgraded ALICE detector readout technology. The software framework was optimized and extended to cope with the increased data load. Online calibration of the TPC using online tracking capabilities of the ALICE HLT was deployed. Offline calibration code was adapted to run both online and offline and the HLT framework was extended to support that. The performance of this schema is important for Run 3 related developments. An additional data transport approach was developed using the ZeroMQ library, forming at the same time a test bed for the new data flow model of the O2 system, where further development of this concept is ongoing. This messaging technology was used to implement the calibration feedback loop augmenting the existing, graph oriented HLT transport framework. Utilising the online reconstruction of many detectors, a new asynchronous monitoring scheme was developed to allow real-time monitoring of the physics performance of the ALICE detector, on top of the new messaging scheme for both internal and external communication. Spare computing resources comprising the production and development clusters are run as a tier-2 GRID site using an OpenStack-based setup. The development cluster is running continuously, the production cluster contributes resources opportunistically during periods of LHC inactivity.

Renewable energy, carbon emissions, and economic growth in 24 Asian countries: evidence from panel cointegration analysis.

PubMed

Lu, Wen-Cheng

2017-11-01

This article aims to investigate the relationship among renewable energy consumption, carbon dioxide (CO 2 ) emissions, and GDP using panel data for 24 Asian countries between 1990 and 2012. Panel cross-sectional dependence tests and unit root test, which considers cross-sectional dependence across countries, are used to ensure that the empirical results are correct. Using the panel cointegration model, the vector error correction model, and the Granger causality test, this paper finds that a long-run equilibrium exists among renewable energy consumption, carbon emission, and GDP. CO 2 emissions have a positive effect on renewable energy consumption in the Philippines, Pakistan, China, Iraq, Yemen, and Saudi Arabia. A 1% increase in GDP will increase renewable energy by 0.64%. Renewable energy is significantly determined by GDP in India, Sri Lanka, the Philippines, Thailand, Turkey, Malaysia, Jordan, United Arab Emirates, Saudi Arabia, and Mongolia. A unidirectional causality runs from GDP to CO 2 emissions, and two bidirectional causal relationships were found between CO 2 emissions and renewable energy consumption and between renewable energy consumption and GDP. The findings can assist governments in curbing pollution from air pollutants, execute energy conservation policy, and reduce unnecessary wastage of energy.

Method of well testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ringgenberg, P.D.; Burris, W.J.

1988-06-28

A method is described of flow testing a formation in a wellbore, comprising: providing a testing string including at least one annulus pressure responsive tool bore closure valve; providing a packer and setting the packer in the wellbore to seal thereacross; running the testing string into the wellbore with the tool bore closure valve in an open position; stinging into the set packer with the bottom of the testing string; increasing pressure a first time in the wellbore annulus around the testing string and above the set packer without cycling the tool bore closure valve; reducing pressure in the wellboremore » annulus; closing the tool bore closure valve responsive to the pressure reduction; increasing pressure a second time in the wellbore annulus; reopening the tool bore closure valve responsive to the second increase; and flowing fluids from the formation through the reopened tool bore closure valve.« less

40 CFR 91.409 - Engine dynamometer test run.

Code of Federal Regulations, 2014 CFR

2014-07-01

... all pre-test data specified in § 91.405(c). (4) Start the test cycle (see § 91.410) within 10 minutes... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Engine dynamometer test run. 91.409... (CONTINUED) CONTROL OF EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Gaseous Exhaust Test Procedures § 91.409...

40 CFR 91.409 - Engine dynamometer test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

... all pre-test data specified in § 91.405(c). (4) Start the test cycle (see § 91.410) within 10 minutes... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Engine dynamometer test run. 91.409... (CONTINUED) CONTROL OF EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Gaseous Exhaust Test Procedures § 91.409...

40 CFR 89.407 - Engine dynamometer test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Perform the pre-test procedure as specified in § 89.406. (3) Read and record the general test data as... (c)(5)(i) through (iii) of this section. (6) Read and record all pre-test data specified in § 89.405... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Engine dynamometer test run. 89.407...

40 CFR 91.409 - Engine dynamometer test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

... all pre-test data specified in § 91.405(c). (4) Start the test cycle (see § 91.410) within 10 minutes... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Engine dynamometer test run. 91.409... (CONTINUED) CONTROL OF EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Gaseous Exhaust Test Procedures § 91.409...

40 CFR 89.407 - Engine dynamometer test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Perform the pre-test procedure as specified in § 89.406. (3) Read and record the general test data as... (c)(5)(i) through (iii) of this section. (6) Read and record all pre-test data specified in § 89.405... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Engine dynamometer test run. 89.407...

40 CFR 91.409 - Engine dynamometer test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

... all pre-test data specified in § 91.405(c). (4) Start the test cycle (see § 91.410) within 10 minutes... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Engine dynamometer test run. 91.409... (CONTINUED) CONTROL OF EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Gaseous Exhaust Test Procedures § 91.409...

40 CFR 89.407 - Engine dynamometer test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Perform the pre-test procedure as specified in § 89.406. (3) Read and record the general test data as... (c)(5)(i) through (iii) of this section. (6) Read and record all pre-test data specified in § 89.405... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Engine dynamometer test run. 89.407...

40 CFR 91.409 - Engine dynamometer test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

... all pre-test data specified in § 91.405(c). (4) Start the test cycle (see § 91.410) within 10 minutes... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Engine dynamometer test run. 91.409... (CONTINUED) CONTROL OF EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Gaseous Exhaust Test Procedures § 91.409...

40 CFR 89.407 - Engine dynamometer test run.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Perform the pre-test procedure as specified in § 89.406. (3) Read and record the general test data as... (c)(5)(i) through (iii) of this section. (6) Read and record all pre-test data specified in § 89.405... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Engine dynamometer test run. 89.407...

40 CFR 89.407 - Engine dynamometer test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Perform the pre-test procedure as specified in § 89.406. (3) Read and record the general test data as... (c)(5)(i) through (iii) of this section. (6) Read and record all pre-test data specified in § 89.405... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Engine dynamometer test run. 89.407...

Supervised oral HIV self-testing is accurate in rural KwaZulu-Natal, South Africa.

PubMed

Martínez Pérez, Guillermo; Steele, Sarah J; Govender, Indira; Arellano, Gemma; Mkwamba, Alec; Hadebe, Menzi; van Cutsem, Gilles

2016-06-01

To achieve UNAIDS 90-90-90 targets, alternatives to conventional HIV testing models are necessary in South Africa to increase population awareness of their HIV status. One of the alternatives is oral mucosal transudates-based HIV self-testing (OralST). This study describes implementation of counsellor-introduced supervised OralST in a high HIV prevalent rural area. Cross-sectional study conducted in two government-run primary healthcare clinics and three Médecins Sans Frontières-run fixed-testing sites in uMlalazi municipality, KwaZulu-Natal. Lay counsellors sampled and recruited eligible participants, sought informed consent and demonstrated the use of the OraQuick(™) OralST. The participants used the OraQuick(™) in front of the counsellor and underwent a blood-based Determine(™) and a Unigold(™) rapid diagnostic test as gold standard for comparison. Primary outcomes were user error rates, inter-rater agreement, sensitivity, specificity and predictive values. A total of 2198 participants used the OraQuick(™) , of which 1005 were recruited at the primary healthcare clinics. Of the total, 1457 (66.3%) were women. Only two participants had to repeat their OraQuick(™) . Inter-rater agreement was 99.8% (Kappa 0.9925). Sensitivity for the OralST was 98.7% (95% CI 96.8-99.6), and specificity was 100% (95% CI 99.8-100). This study demonstrates high inter-rater agreement, and high accuracy of supervised OralST. OralST has the potential to increase uptake of HIV testing and could be offered at clinics and community testing sites in rural South Africa. Further research is necessary on the potential of unsupervised OralST to increase HIV status awareness and linkage to care. © 2016 John Wiley & Sons Ltd.

12 CFR 252.152 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) ENHANCED PRUDENTIAL STANDARDS (REGULATION YY) Company-Run Stress Test Requirements for Banking... on the first day of a stress test cycle (on October 1) over which the relevant projections extend. (k... in the company-run stress tests, including, but not limited to, baseline, adverse, and severely...

Tradeoffs between impact loading rate, vertical impulse and effective mass for walkers and heel strike runners wearing footwear of varying stiffness.

PubMed

Addison, Brian J; Lieberman, Daniel E

2015-05-01

Humans experience repetitive impact forces beneath the heel during walking and heel strike running that cause impact peaks characterized by high rates and magnitudes of loading. Impact peaks are caused by the exchange of momentum between the ground and a portion of the body that comes to a full stop (the effective mass) during the period of the impact peak. A number of factors can influence this exchange of momentum, including footwear stiffness. This study presents and tests an impulse-momentum model of impact mechanics which predicts that effective mass and vertical impulse is greater in walkers and heel strike runners wearing less stiff footwear. The model also predicts a tradeoff between impact loading rate and effective mass, and between impact loading rate and vertical impulse among individuals wearing footwear of varying stiffness. We tested this model using 19 human subjects walking and running in minimal footwear and in two experimental footpads. Subjects walked and ran on an instrumented treadmill and 3D kinematic data were collected. As predicted, both vertical impulse (walking: F(2,54)=52.0, p=2.6E-13; running: F(2,54)=25.2, p=1.8E-8) and effective mass (walking: F(2,54)=12.1, p=4.6E-5; running: F(2,54)=15.5, p=4.7E-6) increase in less stiff footwear. In addition, there is a significant inverse relationship between impact loading rate and vertical impulse (walking: r=-0.88, p<0.0001; running: r=-0.78, p<0.0001) and between impact loading rate and effective mass (walking: r=-0.88, p<0.0001; running: r=-0.82, p<0.0001). The tradeoff relationships documented here raise questions about how and in what ways the stiffness of footwear heels influence injury risk during human walking and running. Copyright © 2015 Elsevier Ltd. All rights reserved.

Warm-up with a weighted vest improves running performance via leg stiffness and running economy.

PubMed

Barnes, K R; Hopkins, W G; McGuigan, M R; Kilding, A E

2015-01-01

To determine the effects of "strides" with a weighted-vest during a warm-up on endurance performance and its potential neuromuscular and metabolic mediators. A bout of resistance exercise can enhance subsequent high-intensity performance, but little is known about such priming exercise for endurance performance. A crossover with 5-7 days between an experimental and control trial was performed by 11 well-trained distance runners. Each trial was preceded by a warm-up consisting of a 10-min self-paced jog, a 5-min submaximal run to determine running economy, and six 10-s strides with or without a weighted-vest (20% of body mass). After a 10-min recovery period, runners performed a series of jumps to determine leg stiffness and other neuromuscular characteristics, another 5-min submaximal run, and an incremental treadmill test to determine peak running speed. Clinical and non-clinical forms of magnitude-based inference were used to assess outcomes. Correlations and linear regression were used to assess relationships between performance and underlying measures. The weighted-vest condition resulted in a very-large enhancement of peak running speed (2.9%; 90% confidence limits ±0.8%), a moderate increase in leg stiffness (20.4%; ±4.2%) and a large improvement in running economy (6.0%; ±1.6%); there were also small-moderate clear reductions in cardiorespiratory measures. Relationships between change scores showed that changes in leg stiffness could explain all the improvements in performance and economy. Strides with a weighted-vest have a priming effect on leg stiffness and running economy. It is postulated the associated major effect on peak treadmill running speed will translate into enhancement of competitive endurance performance. Copyright © 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

The Reliability of a 5km Run Test on a Motorized Treadmill

ERIC Educational Resources Information Center

Driller, Matthew; Brophy-Williams, Ned; Walker, Anthony

2017-01-01

The purpose of the present study was to determine the reliability of a 5km run test on a motorized treadmill. Over three consecutive weeks, 12 well-trained runners completed three 5km time trials on a treadmill following a standardized warm-up. Runners were partially-blinded to their running speed and distance covered. Total time to complete the…

Comparison of Effects of Running and Playing Exercises on Differential Leucocyte Count in Young Elite Athletes

ERIC Educational Resources Information Center

Cenikli, Abdullah

2016-01-01

The aims of the present research are to test the effects of running and playing exercises on leucocyte and differential leucocyte accounts, and to test the possible differences between running and playing exercises in terms of leucocyte accounts. They were thirty two male young soccer players. Participants arrived at the laboratory after a 12-hour…

Catalytic co-aromatization of ethanol and methane

DOE PAGES

Wang, Aiguo; He, Peng; Yung, Matthew; ...

2016-06-06

This study demonstrates the technical feasibility of simultaneously converting ethanol and methane into liquid hydrocarbons at mild reaction conditions (400 °C and 1 atm) over silver and/or zinc modified zeolite catalysts. After GC-MS analysis, it is worth noting that aromatics are the major compounds contained in the liquid product collected from the run when 1%Ag/ZSM-5, particularly after H 2 pretreatment, is charged. Compared to the performance exhibited from the run with pure HZSM-5 support engaged, Ag addition into the HZSM-5 framework favors aromatics formation, which might be closely associated with better Ag dispersion and more abundance of strong surface acidicmore » sites where aromatization might take place while Zn loading exerts a detrimental effect on the production of aromatics but promotes the ether generation possibly through dehydration reaction. Referred to that from its N 2 counterpart, the increased aromatics formation of the collected liquid product when methane is present indicates that methane existence might facilitate ethanol aromatization. Moreover, combined with the increased carbon number in the formed aromatics from CH 4 run when H 2 run is referred and zero liquid formation from CH 4-alone test as well as more prominent endothermic feature of methane run and more importantly the notably increased 13C signals in 13C NMR spectra of the liquid product collected during ethanol conversion under 13CH 4 environment, all the observations suggest that methane might be activated nonoxidatively and converted into higher hydrocarbons, preferentially into aromatics if suitable catalyst is charged under the assistance of co-existing oxygenated hydrocarbon. Lastly, the reported synergetic effect could potentially lead to the more economic utilization of abundant natural gas and cellulosic ethanol.« less

Responding for sucrose and wheel-running reinforcement: effect of pre-running.

PubMed

Belke, Terry W

2006-01-10

Six male albino Wistar rats were placed in running wheels and exposed to a fixed interval 30-s schedule that produced either a drop of 15% sucrose solution or the opportunity to run for 15s as reinforcing consequences for lever pressing. Each reinforcer type was signaled by a different stimulus. To assess the effect of pre-running, animals were allowed to run for 1h prior to a session of responding for sucrose and running. Results showed that, after pre-running, response rates in the later segments of the 30-s schedule decreased in the presence of a wheel-running stimulus and increased in the presence of a sucrose stimulus. Wheel-running rates were not affected. Analysis of mean post-reinforcement pauses (PRP) broken down by transitions between successive reinforcers revealed that pre-running lengthened pausing in the presence of the stimulus signaling wheel running and shortened pauses in the presence of the stimulus signaling sucrose. No effect was observed on local response rates. Changes in pausing in the presence of stimuli signaling the two reinforcers were consistent with a decrease in the reinforcing efficacy of wheel running and an increase in the reinforcing efficacy of sucrose. Pre-running decreased motivation to respond for running, but increased motivation to work for food.

Caffeine-containing energy drink improves physical performance in female soccer players.

PubMed

Lara, Beatriz; Gonzalez-Millán, Cristina; Salinero, Juan Jose; Abian-Vicen, Javier; Areces, Francisco; Barbero-Alvarez, Jose Carlos; Muñoz, Víctor; Portillo, Luis Javier; Gonzalez-Rave, Jose Maria; Del Coso, Juan

2014-05-01

There is little information about the effects of caffeine intake on female team-sport performance. The aim of this study was to investigate the effectiveness of a caffeine-containing energy drink to improve physical performance in female soccer players during a simulated game. A double-blind, placebo controlled and randomized experimental design was used in this investigation. In two different sessions, 18 women soccer players ingested 3 mg of caffeine/kg in the form of an energy drink or an identical drink with no caffeine content (placebo). After 60 min, they performed a countermovement jump (CMJ) and a 7 × 30 m sprint test followed by a simulated soccer match (2 × 40 min). Individual running distance and speed were measured using GPS devices. In comparison to the placebo drink, the ingestion of the caffeinated energy drink increased the CMJ height (26.6 ± 4.0 vs 27.4 ± 3.8 cm; P < 0.05) and the average peak running speed during the sprint test (24.2 ± 1.6 vs 24.5 ± 1.7 km/h; P < 0.05). During the simulated match, the energy drink increased the total running distance (6,631 ± 1,618 vs 7,087 ± 1,501 m; P < 0.05), the number of sprints bouts (16 ± 9 vs 21 ± 13; P < 0.05) and the running distance covered at >18 km/h (161 ± 99 vs 216 ± 103 m; P < 0.05). The ingestion of the energy drink did not affect the prevalence of negative side effects after the game. An energy drink with a dose equivalent to 3 mg of caffeine/kg might be an effective ergogenic aid to improve physical performance in female soccer players.

Physiological consequences of military high-speed boat transits.

PubMed

Myers, Stephen D; Dobbins, Trevor D; King, Stuart; Hall, Benjamin; Ayling, Ruth M; Holmes, Sharon R; Gunston, Tom; Dyson, Rosemary

2011-09-01

The purpose of this study was to investigate the consequences of a high-speed boat transit on physical performance. Twenty-four Royal Marines were randomly assigned to a control (CON) or transit (TRAN) group. The CON group sat onshore for 3 h whilst the TRAN group completed a 3-h transit in open-boats running side-by-side, at 40 knots in moderate-to-rough seas, with boat deck and seat-pan acceleration recorded. Performance tests (exhaustive shuttle-run, handgrip, vertical-jump, push-up) were completed pre- and immediately post-transit/sit, with peak heart rate (HRpeak) and rating of perceived exertion (RPE) recorded. Serial blood samples (pre, 24, 36, 48, 72 h) were analyzed for creatine kinase (CK) activity. The transit was typified by frequent high shock impacts, but moderate mean heart rates (<45% HRpeak). The TRAN group post-transit run distance (-219 m, P < 0.01) and vertical-jump height (5%, P < 0.05) were reduced, the CON group showed no change. The TRAN group post-transit test RPE increased (P < 0.05), however, HRpeak was similar for each group (98%). Post-transit CK activity increased in the TRAN group up to 72 h (P < 0.01) and also, but less markedly, in the CON group (24 and 48 h, P < 0.05). Post-transit run and jump performances were reduced despite mean transit heart rates indicating low energy expenditure. The greater TRAN CK activity suggests muscle damage may have been a contributory factor. These findings have operational implications for Special Forces/naval/police/rescue services carrying out demanding, high-risk physical tasks during and immediately after high-speed boat transits.

Small axial compressor technology, volume 1

NASA Technical Reports Server (NTRS)

Holman, F. F.; Kidwell, J. R.; Ware, T. C.

1976-01-01

A scaled single-stage, highly-loaded, axial-flow transonic compressor was tested at speeds from 70 to 110% design equivalent speed to evaluate the effects of scaling compromises and the individual and combined effects of rotor tip running clearance and rotor shroud casing treatment on the overall and blade element performance. At design speed and 1% tip clearance the stage demonstrated an efficiency of 83.2% at 96.4% design flow and a pressure ratio of 1.865. Casing treatment increased design speed surge margin 2.0 points to 12.8%. Overall performance was essentially unchanged. An increase in rotor running clearance to 2.2%, with smooth casing, reduced design speed peak efficiency 5.7 points, flow by 7.4%, pressure ratio to 1.740, and surge margin to 5.4%. Reinstalling casing treatment regained 3.5 points in design speed peak efficiency, 4.7% flow, increased pressure ratio to 1.800 and surge margin to 8.7%.

Fitness Assessment Comparison Between the “Jackie Chan Action Run” Videogame, 1-Mile Run/Walk, and the PACER

PubMed Central

Siegel, Shannon; Costa, Pablo; Jarvis, Sarah; Klug, Nicholas; Medina, Ernie; Wilkin, Linda

2012-01-01

Abstract Objective The purpose of this study was to examine whether a correlation existed among the scores of the “Jackie Chan Studio Fitness™ Action Run” active videogame (XaviX®, SSD Company, Ltd., Kusatsu, Japan), the 1-mile run/walk, and Progressive Aerobic Cardiovascular Endurance Run (PACER) aerobic fitness tests of the FITNESSGRAM® (The Cooper Institute, Dallas, TX) in order to provide a potential alternative testing method for days that are not environmentally desirable for outdoor testing. Subjects and Methods Participants were a convenience sample from physical education classes of students between the ages of 10 and 15 years. Participants (n=108) were randomly assigned to one of three groups with the only difference being the order of testing. The tests included the “Jackie Chan Action Run” active videogame, the 1-mile run/walk, and the PACER. Testing occurred on three different days during the physical education class. Rating of perceived exertion (RPE) was reported. Results Significant correlations (r=−0.598 to 0.312) were found among the three aerobic fitness tests administered (P<0.05). The RPE for the “Jackie Chan Action Run” was lower than the RPE for the 1-mile run/walk and the PACER (3.81±1.89, 5.93±1.77, and 5.71±2.14, respectively). Conclusions The results suggest that the “Jackie Chan Action Run” test could be an alternative to the 1-mile run/walk and PACER, allowing physical education teachers to perform aerobic fitness testing in an indoor setting that requires less space. Also, children may be more willing to participate in the “Jackie Chan Action Run” based on the lower RPE. PMID:26193440

16 Weeks of Progressive Barefoot Running Training Changes Impact Force and Muscle Activation in Habitual Shod Runners

PubMed Central

Mezêncio, Bruno; Amadio, Alberto Carlos; Serrão, Julio Cerca

2016-01-01

Short-term effects of barefoot and simulated barefoot running have been widely discussed in recent years. Consequences of adopting barefoot running for a long period, including as a training approach, still remain unknown. The present study evaluated the influence of 16 weeks of progressive barefoot running training on impact force and muscle activation in habitual shod runners. Six habitual shod runners (3 men and 3 women, 29.5 ± 7.3 years) were tested barefoot (BF) and shod (SH), before and after 16 weeks of progressive barefoot running training. Tests consisted of running on instrumented treadmill at 9 km/h, for 10 minutes in each experimental condition. Nine data acquisitions (10 s) of vertical ground reaction force (VGRF) and electromyographic (EMG) signal were conducted in each experimental condition for each test. BF training was effective to alter VGRF and EMG parameters of running in habitual shod runners, regardless of footwear condition (SH or BF). The magnitude of first peak of VGRF (Fy1) and the impulse of the first 50 ms decreased after training for BF and SH (p<0.01). The activation reduced from PRE to POST training for four muscles in BF running (p<0.001), whereas only muscle gastrocnemius lateralis decreased significantly its activation (p<0.01) in SH running. A 16-week progressive barefoot running training seems to be an effective training strategy to reduce impact force, improve shock attenuation and to decrease muscle activation intensity, not only in BF running, but also in SH running, although BF condition seems to be more influenced by BF training. PMID:27907069

The effects of below-elbow immobilization on driving performance.

PubMed

Jones, Evan M; Barrow, Aaron E; Skordas, Nic J; Green, David P; Cho, Mickey S

2017-02-01

There is limited research to guide physicians and patients in deciding whether it is safe to drive while wearing various forms of upper extremity immobilization. The purpose of this study is to evaluate the effect of below-elbow removable splints and fiberglass casts on automobile driving performance. 20 healthy subjects completed 10 runs through a closed, cone-marked driving course while wearing a randomized sequence of four different types of immobilization on each extremity (short arm thumb spica fiberglass cast, short arm fiberglass cast, short arm thumb spica splint, and short arm wrist splint). The first and last driving runs were without immobilization and served as controls. Performance was measured based on evaluation by a certified driving instructor (pass/fail scoring), cones hit, run time, and subject-perceived driving difficulty (1-10 analogue scoring). The greatest number of instructor-scored failures occurred while immobilized in right arm spica casts (n=6; p=0.02) and left arm spica casts (n=5; p=0.049). The right arm spica cast had the highest subject-perceived difficulty (5.2±1.9; p<0.001). All forms of immobilization had significantly increased perceived difficulty compared to control, except for the left short arm splint (2.5±1.6; p>0.05). There was no significant difference in number of cones hit or driving time between control runs and runs with any type of immobilization. Drivers should use caution when wearing any of the forms of upper extremity immobilization tested in this study. All forms of immobilization, with exception of the left short arm splint significantly increased perceived driving difficulty. However, only the fiberglass spica casts (both left and right arm), significantly increased drive run failures due to loss of vehicle control. We recommend against driving when wearing a below-elbow fiberglass spica cast on either extremity. Copyright © 2016. Published by Elsevier Ltd.

Hippocampal Neurogenesis and Dendritic Plasticity Support Running-Improved Spatial Learning and Depression-Like Behaviour in Stressed Rats

PubMed Central

Tong, Jian-Bin; Wong, Richard; Ching, Yick-Pang; Qiu, Guang; Tang, Siu-Wa; Lee, Tatia M. C.; So, Kwok-Fai

2011-01-01

Exercise promotes hippocampal neurogenesis and dendritic plasticity while stress shows the opposite effects, suggesting a possible mechanism for exercise to counteract stress. Changes in hippocampal neurogenesis and dendritic modification occur simultaneously in rats with stress or exercise; however, it is unclear whether neurogenesis or dendritic remodeling has a greater impact on mediating the effect of exercise on stress since they have been separately examined. Here we examined hippocampal cell proliferation in runners treated with different doses (low: 30 mg/kg; moderate: 40 mg/kg; high: 50 mg/kg) of corticosterone (CORT) for 14 days. Water maze task and forced swim tests were applied to assess hippocampal-dependent learning and depression-like behaviour respectively the day after the treatment. Repeated CORT treatment resulted in a graded increase in depression-like behaviour and impaired spatial learning that is associated with decreased hippocampal cell proliferation and BDNF levels. Running reversed these effects in rats treated with low or moderate, but not high doses of CORT. Using 40 mg/kg CORT-treated rats, we further studied the role of neurogenesis and dendritic remodeling in mediating the effects of exercise on stress. Co-labelling with BrdU (thymidine analog) /doublecortin (immature neuronal marker) showed that running increased neuronal differentiation in vehicle- and CORT-treated rats. Running also increased dendritic length and spine density in CA3 pyramidal neurons in 40 mg/kg CORT-treated rats. Ablation of neurogenesis with Ara-c infusion diminished the effect of running on restoring spatial learning and decreasing depression-like behaviour in 40 mg/kg CORT-treated animals in spite of dendritic and spine enhancement. but not normal runners with enhanced dendritic length. The results indicate that both restored hippocampal neurogenesis and dendritic remodelling within the hippocampus are essential for running to counteract stress. PMID:21935393

Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons

PubMed Central

Noble, Emily E.; Mavanji, Vijayakumar; Little, Morgan R.; Billington, Charles J.; Kotz, Catherine M.; Wang, ChuanFeng

2014-01-01

Background Previous studies have shown that a western diet impairs, whereas physical exercise enhances hippocampus-dependent learning and memory. Both diet and exercise influence expression of hippocampal brain-derived neurotrophic factor (BDNF), which is associated with improved cognition. We hypothesized that exercise reverses diet-induced cognitive decline while increasing hippocampal BDNF. Methods To test the effects of exercise on hippocampal-dependent memory, we compared cognitive scores of Sprague-Dawley rats exercised by voluntary running wheel (RW) access or forced treadmill (TM) to sedentary (Sed) animals. Memory was tested by two-way active avoidance test (TWAA), in which animals are exposed to a brief shock in a specific chamber area. When an animal avoids, escapes or has reduced latency to do either, this is considered a measure of memory. In a second experiment, rats were fed either a high-fat diet or control diet for 16 weeks, then randomly assigned to running wheel access or sedentary condition, and TWAA memory was tested once a week for seven weeks of exercise intervention. Results Both groups of exercised animals had improved memory as indicated by reduced latency to avoid and escape shock, and increased avoid and escape episodes (p<0.05). Exposure to a high-fat diet resulted in poor performance during both the acquisition and retrieval phases of the memory test as compared to controls. Exercise reversed high-fat diet-induced memory impairment, and increased brain-derived neurotrophic factor (BDNF) in neurons of the hippocampal CA3 region. Conclusions These data suggest that exercise improves memory retrieval, particularly with respect to avoiding aversive stimuli, and may be beneficial in protecting against diet induced cognitive decline, likely via elevated BDNF in neurons of the CA3 region. PMID:24755094

Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons.

PubMed

Noble, Emily E; Mavanji, Vijayakumar; Little, Morgan R; Billington, Charles J; Kotz, Catherine M; Wang, ChuanFeng

2014-10-01

Previous studies have shown that a western diet impairs, whereas physical exercise enhances hippocampus-dependent learning and memory. Both diet and exercise influence expression of hippocampal brain-derived neurotrophic factor (BDNF), which is associated with improved cognition. We hypothesized that exercise reverses diet-induced cognitive decline while increasing hippocampal BDNF. To test the effects of exercise on hippocampal-dependent memory, we compared cognitive scores of Sprague-Dawley rats exercised by voluntary running wheel (RW) access or forced treadmill (TM) to sedentary (Sed) animals. Memory was tested by two-way active avoidance test (TWAA), in which animals are exposed to a brief shock in a specific chamber area. When an animal avoids, escapes or has reduced latency to do either, this is considered a measure of memory. In a second experiment, rats were fed either a high-fat diet or control diet for 16 weeks, then randomly assigned to running wheel access or sedentary condition, and TWAA memory was tested once a week for 7 weeks of exercise intervention. Both groups of exercised animals had improved memory as indicated by reduced latency to avoid and escape shock, and increased avoid and escape episodes (p<0.05). Exposure to a high-fat diet resulted in poor performance during both the acquisition and retrieval phases of the memory test as compared to controls. Exercise reversed high-fat diet-induced memory impairment, and increased brain-derived neurotrophic factor (BDNF) in neurons of the hippocampal CA3 region. These data suggest that exercise improves memory retrieval, particularly with respect to avoiding aversive stimuli, and may be beneficial in protecting against diet induced cognitive decline, likely via elevated BDNF in neurons of the CA3 region. Published by Elsevier Inc.

Running economy and body composition between competitive and recreational level distance runners.

PubMed

Mooses, Martin; Jürimäe, J; Mäestu, J; Mooses, K; Purge, P; Jürimäe, T

2013-09-01

The aim of the present study was to compare running economy between competitive and recreational level athletes at their individual ventilatory thresholds on track and to compare body composition parameters that are related to the individual running economy measured on track. We performed a cross-sectional analysis of a total 45 male runners classified as competitive runners (CR; n = 28) and recreational runners (RR; n = 17). All runners performed an incremental test on treadmill until voluntary exhaustion and at least 48 h later a 2 × 2000 m test at indoor track with intensities according to ventilatory threshold 1, ventilator threshold 2. During the running tests, athletes wore portable oxygen analyzer. Body composition was measured with Dual energy X-ray absorptiometry (DXA) method. Running economy at the first ventilatory threshold was not significantly related to any of the measured body composition values or leg mass ratios either in the competitive or in the recreational runners group. This study showed that there was no difference in the running economy between distance runners with different performance level when running on track, while there was a difference in the second ventilatory threshold speed in different groups of distance runners. Differences in running economy between competitive and recreational athletes cannot be explained by body composition and/or different leg mass ratios.

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and the run average); (B) The raw data and results for all required pre-test, post-test, pre-run and...-day calibration error tests, all daily system integrity checks (Hg monitors, only), and all off-line calibration demonstrations, including any follow-up tests after corrective action: (i) Component-system...

77 FR 62396 - Annual Company-Run Stress Test Requirements for Banking Organizations With Total Consolidated...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

... in the stress test, for each quarter of the planning horizon, aggregate losses, pre-provision net... Company-Run Stress Test Requirements for Banking Organizations With Total Consolidated Assets Over $10... regulatory agency to conduct stress tests on an annual basis. The Board is adopting this final rule to...

Adolescents' Interest and Performances in Aerobic Fitness Testing

ERIC Educational Resources Information Center

Zhu, Xihe; Chen, Senlin; Parrott, James

2014-01-01

This study examined adolescents' interest in aerobic fitness testing and its relation to the test performances. Adolescents (N = 356) from three middle schools participated in the study. The participants took two aerobic fitness tests: the Progressive Aerobic Cardiovascular Endurance Run (PACER) and One-Mile Run (1MR) with a two-day interval, and…

40 CFR 86.535-90 - Dynamometer procedure.

Code of Federal Regulations, 2010 CFR

2010-07-01

... run consists of two tests, a “cold” start test and a “hot” start test following the “cold” start by 10... Administrator. (d) Practice runs over the prescribed driving schedule may be performed at test points, provided... the proper speed-time relationship, or to permit sampling system adjustments. (e) The drive wheel...

Significance of heel pad confinement for the shock absorption at heel strike.

PubMed

Jørgensen, U; Ekstrand, J

1988-12-01

Shock absorption (SA) is a simple way to reduce the body load and can be used in the prevention and treatment of injuries. The heel pad is the most important shock absorber in the shoe heel complex. The purpose of this study was to investigate whether the SA at heel strike can be increased by heel support in people and shoes with high or low SA. The impact forces at heel strike were measured on an AMTI (R) force platform. Fourteen legs were tested in seven persons (nine with normal and five with low heel pad SA) in gait analysis and in human drop tests. The tests were performed barefooted, and in a soccer and a running shoe (selected by shoe drop test), with and without the distal 2 cm of the heel counter. The heel pad confinement produced by the heel counter (the heel counter effect) increased the SA in both shoe types significantly in both impact situations. The mean increase in SA was 8.8% (range 5.8%-15.5%). The heel counter effect was in all situations significantly higher in persons with low heel pad shock absorbency (LHPSA) than in those with normal heel pads. The barefoot impact peak force per kg body weight was significantly higher (6% mean) on the side with LHPSA. The running shoe provided the significantly greatest SA compared with the soccer shoe. It is concluded that the shock absorbency at heel strike can be increased significantly by heel support, with highest effect in persons with LHPSA, both in shoes with high and low SA.(ABSTRACT TRUNCATED AT 250 WORDS)

14 CFR 33.88 - Engine overtemperature test.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Block Tests; Turbine Aircraft Engines § 33.88 Engine overtemperature... this run, the turbine assembly must be within serviceable limits. (b) In addition to the test... this run, the turbine assembly may exhibit distress beyond the limits for an overtemperature condition...

14 CFR 33.88 - Engine overtemperature test.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Block Tests; Turbine Aircraft Engines § 33.88 Engine overtemperature... this run, the turbine assembly must be within serviceable limits. (b) In addition to the test... this run, the turbine assembly may exhibit distress beyond the limits for an overtemperature condition...

14 CFR 33.88 - Engine overtemperature test.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Block Tests; Turbine Aircraft Engines § 33.88 Engine overtemperature... this run, the turbine assembly must be within serviceable limits. (b) In addition to the test... this run, the turbine assembly may exhibit distress beyond the limits for an overtemperature condition...

A low speed wind tunnel test of a 0.050 scale model of shuttle orbiter (model 089B) to investigate the longitudinal and lateral directional effects of canard and tail configurational modifications in the LTV LSWT (MA14)

NASA Technical Reports Server (NTRS)

Chambliss, E. B.

1976-01-01

A low speed wind tunnel test was conducted to determine the effects of 6 canard configurations on the 0.050 scale model of shuttle orbiter 089B. In addition, two horizontal tail configurations were tested at two positions on the model as were two wing configurations. Since this test was restricted to 103 runs, only a limited number of permutations of the configurational changes could be tested. The testing was done in the 15 by 20 foot section of the LSWT and consisted of pitch polars, one yawed polar and several yaw runs. The pitch polars encompassed an alpha range from 0 to 28 deg; the yawed polar was run at beta = +2 degrees and the yaw runs covered a beta range from -6 to +6 deg at angles-of-attack of 0, 4, 10, 16, and 20 deg.

Forward conditioning with wheel running causes place aversion in rats.

PubMed

Masaki, Takahisa; Nakajima, Sadahiko

2008-09-01

Backward pairings of a distinctive chamber as a conditioned stimulus and wheel running as an unconditioned stimulus (i.e., running-then-chamber) can produce a conditioned place preference in rats. The present study explored whether a forward conditioning procedure with these stimuli (i.e., chamber-then-running) would yield place preference or aversion. Confinement of a rat in one of two distinctive chambers was followed by a 20- or 60-min running opportunity, but confinement in the other was not. After four repetitions of this treatment (i.e., differential conditioning), a choice preference test was given in which the rat had free access to both chambers. This choice test showed that the rats given 60-min running opportunities spent less time in the running-paired chamber than in the unpaired chamber. Namely, a 60-min running opportunity after confinement in a distinctive chamber caused conditioned aversion to that chamber after four paired trials. This result was discussed with regard to the opponent-process theory of motivation.

Circadian wheel-running activity during withdrawal from chronic intermittent ethanol exposure in mice

PubMed Central

Logan, Ryan W.; Seggio, Joseph A.; Robinson, Stacy L.; Richard, Gregory R.; Rosenwasser, Alan M.

2010-01-01

Alcohol withdrawal is associated with affective-behavioral disturbances in both human alcoholics and in animal models. In general, these phenomena are potentiated by increased alcohol exposure duration and by prior withdrawal episodes. Previous studies have also reported locomotor hypoactivity during ethanol withdrawal in rats and mice, but only in novel test environments, not in the home-cage. In the present study, we examined the effects of withdrawal from chronic intermittent ethanol (CIE) vapor exposure on the level and circadian periodicity of wheel-running activity in C57BL/6J mice. CIE treatment resulted in reductions in wheel-running activity relative to plain-air controls that persisted for about one week after withdrawal. Analysis of circadian waveforms indicated that reduced activity occurred throughout the night phase, but that daily activity patterns were otherwise unaltered. CIE failed to alter free-running circadian period or phase in animals maintained under constant darkness. These results show that ethanol withdrawal can result in locomotor hypoactivity even in the habitual, home-cage environment, and suggest that withdrawal-related reductions in wheel-running activity may reflect the specific motivational significance of this behavior. PMID:20682191

The Construct Validity of the CODA and Repeated Sprint Ability Tests in Football Referees.

PubMed

Riiser, Amund; Andersen, Vidar; Castagna, Carlo; Arne Pettersen, Svein; Saeterbakken, Atle; Froyd, Christian; Ylvisaker, Einar; Naess Kjosnes, Terje; Fusche Moe, Vegard

2018-06-14

As of 2017, the international football federation introduced the change of direction ability test (CODA) and the 5×30 m sprint test for assistant referees (ARs) and continued the 6×40 m sprint test for field referees (FRs) as mandatory tests. The aim of this study was to evaluate the association between performance in these tests and running performance during matches at the top level in Norway. The study included 9 FRs refereeing 21 matches and 19 ARs observed 53 times by a local positioning system at three stadiums during the 2016 season. Running performance during matches was assessed by high-intensity running (HIR) distance, HIR counts, acceleration distance, and acceleration counts. For the ARs, there was no association between the CODA test with high-intensity running or acceleration ( P >0.05). However, the 5×30 m sprint test was associated with HIR count during the entire match (E -12.9, 95% CI -25.4 to -0.4) and the 5-min period with the highest HIR count (E -2.02, 95% CI -3.55 to -0.49). For the FRs, the 6×40 m fitness test was not associated with running performance during matches ( P >0.05). In conclusion, performance in these tests had weak or no associations with accelerations or HIR in top Norwegian referees during match play. © Georg Thieme Verlag KG Stuttgart · New York.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Twelve catalyst test runs were made; ten of these runs used catalysts that contained cobalt as the metal component, while the remaining two runs used catalysts that contained iron as the metal component. Five of the ten cobalt catalyst test runs were made with the catalysts containing one of two different shape selective components (UCC-101 and UCC-108) at two different metal component: shape selective component ratios (1:1 and 3:14). The remaining five cobalt catalyst test runs were made with the catalysts containing different additives incorporated into the cobalt. The five cobalt catalyst test runs using catalysts with different additives showedmore » that these additives had pronounced effects on the catalysts' activity, selectivity, and stability. The most outstanding effect was realized with the additive used in the Run 9 catalyst. This additive greatly improved the stability of the catalyst. While having the same initial activity of an additive-free catalyst, its deactivation rate was only one fourth of that of the additive-free catalyst. Futhermore, this additive improved the quality of the hydrocarbon product, which had a high, stable yield of olefins, and, unlike the product of any other cobalt/UCC-101 catalyst, was free of suspended wax. This lack of suspended wax resulted in jet fuel and diesel oil fractions that had substantially lower pour points than did the fractions produced from an additive-free catalyst.« less

Effects of physical exercise and social isolation on anxiety-related behaviors in two inbred rat strains.

PubMed

Mazur, F G; Oliveira, L F G; Cunha, M P; Rodrigues, A L S; Pértile, R A N; Vendruscolo, L F; Izídio, G S

2017-09-01

We investigated the effects of physical exercise (PE) on locomotor activity and anxiety-like behavior in Lewis (LEW) and Spontaneously Hypertensive Rats (SHR) male rats. Rats received either four weeks of forced training, 5days/week, on a treadmill (experiment 1) or were given 21days of free access to running wheels (experiment 2). We also tested the effects of social isolation (SI) (seven days of isolation - experiment 3) on behavior. In experiment 1, 20% of LEW rats and 63% of SHR rats completed the training protocol. PE significantly increased central and peripheral locomotion in the open field (OF) and entries into the open arms in the elevated plus-maze (EPM) in both strains. In experiment 2, the distance traveled by SHR rats on running wheels was significantly higher compared with LEW rats. PE on running wheels also increased the time spent in the center of the OF in SHR rats only. In experiment 3, SI decreased central and peripheral locomotion in the OF in both strains. In summary, forced PE on a treadmill reduced anxiety-like behavior and increased locomotion in male rats of both strains, whereas voluntary PE on running wheels decreased anxiety-like behavior in SHR rats only. SI decreased locomotion in both strains in the OF. This study suggests that spontaneous activity levels are genotype-dependent and the effects of PE depend on the type of exercise performed. Copyright © 2017 Elsevier B.V. All rights reserved.

Increased xanthine oxidase-related ROS production and TRPV1 synthesis preceding DOMS post-eccentric exercise in rats.

PubMed

Retamoso, Leandro T; Silveira, Mauro E P; Lima, Frederico D; Busanello, Guilherme L; Bresciani, Guilherme; Ribeiro, Leandro R; Chagas, Pietro M; Nogueira, Cristina W; Braga, Ana Claudia M; Furian, Ana Flávia; Oliveira, Mauro S; Fighera, Michele R; Royes, Luiz Fernando F

2016-05-01

It is well-known that unaccustomed exercise, especially eccentric exercise, is associated to delayed onset muscle soreness (DOMS). Whether DOMS is associated with reactive oxygen species (ROS) and the transient receptor potential vanilloid 1 (TRPV1) is still an open question. Thus, the aim of this study was to investigate the association between TRPV1 and xanthine oxidase-related ROS production in muscle and DOMS after a bout of eccentric exercise. Male Wistar rats performed a downhill running exercise on a treadmill at a -16° tilt and a constant speed for 90min (5min/bout separated by 2min of rest). Mechanical allodynia and grip force tests were performed before and 1, 3, 6, 9, 12, 24, 48 and 72h after the downhill running. Biochemical assays probing oxidative stress, purine degradation, xanthine oxidase activity, Ca(2+) ATPase activity and TRPV1 protein content were performed in gastrocnemius muscle at 12, 24, and 48h after the downhill running. Our statistical analysis showed an increase in mechanical allodynia and a loss of strength after the downhill running. Similarly, an increase in carbonyl, xanthine oxidase activity, uric acid levels and TRPV1 immunoreactivity were found 12h post-exercise. On the other hand, Ca(2+) ATPase activity decreased in all analyzed times. Our results suggest that a possible relationship between xanthine oxidase-related ROS and TRPV1 may exist during the events preceding eccentric exercise-related DOMS. Copyright © 2016 Elsevier Inc. All rights reserved.

Comparison of step-by-step kinematics in repeated 30m sprints in female soccer players.

PubMed

van den Tillaar, Roland

2018-01-04

The aim of this study was to compare kinematics in repeated 30m sprints in female soccer players. Seventeen subjects performed seven 30m sprints every 30s in one session. Kinematics were measured with an infrared contact mat and laser gun, and running times with an electronic timing device. The main findings were that sprint times increased in the repeated sprint ability test. The main changes in kinematics during the repeated sprint ability test were increased contact time and decreased step frequency, while no change in step length was observed. The step velocity increased in almost each step until the 14, which occurred around 22m. After this, the velocity was stable until the last step, when it decreased. This increase in step velocity was mainly caused by the increased step length and decreased contact times. It was concluded that the fatigue induced in repeated 30m sprints in female soccer players resulted in decreased step frequency and increased contact time. Employing this approach in combination with a laser gun and infrared mat for 30m makes it very easy to analyse running kinematics in repeated sprints in training. This extra information gives the athlete, coach and sports scientist the opportunity to give more detailed feedback and help to target these changes in kinematics better to enhance repeated sprint performance.

Physical Fitness and Body Anthropometrics Profiles of the Female Recruits Entering to Voluntary Military Service.

PubMed

Santtila, Matti; Pihlainen, Kai; Koski, Harri; Ojanen, Tommi; Kyröläinen, Heikki

2018-06-13

The physical fitness of male conscripts has decreased, and body mass increased during the last few decades, especially in Nordic countries. However, limited research-based reports are available concerning the physical fitness profiles of female recruits. Therefore, the purpose of this study was to investigate changes in physical fitness and body composition of female recruits entering voluntary Finnish military service between the years 2005 and 2015. Data were collected from the initial fitness tests performed in military units during the first 2 weeks of military service. A total of 3,875 healthy female recruits (19.9 ± 2.1 year) participated in the fitness tests. Fitness tests consisted 12-minute running test and muscle fitness tests, which were sit-ups, push-ups, and standing long jump. Increases in mean body mass (4.2%, p ≤ 0.01) and body mass index (3.8%, p < 0.01) were observed between 2005 and 2015. In addition, the proportion of overweight and obese female recruits increased by 12% (p ≤ 0.001). Mean endurance performance and overall muscle fitness remained unaltered during the study period, except for a decline in push-ups performance. However, the proportion of female recruits with poor endurance performance increased from 19.6% to 27.8% (p ≤ 0.001) between 2005 and 2015. Body mass was inversely associated with 12-minute running test distance (r = -0.35, p ≤ 0.001) and muscle fitness index (r = -0.25, p ≤ 0.001). In conclusion, the present study revealed that an increasing proportion of female recruits are overweight and/or have poor endurance performance, which are known risk factors for musculoskeletal injuries and premature discharge from military service. Therefore, specialized training programs should be designed specifically for female recruits with lower levels of fitness prior to military service.

The role of the estrogen receptor α in the medial preoptic area in sexual incentive motivation, proceptivity and receptivity, anxiety, and wheel running in female rats.

PubMed

Spiteri, Thierry; Ogawa, Sonoko; Musatov, Sergei; Pfaff, Donald W; Agmo, Anders

2012-04-21

Ovariectomized females were given an infusion in the medial preoptic area (MPOA) of a viral vector carrying either a shRNA directed against the estrogen receptor α (ERα) or luciferase. The females were subjected to a test for sexual incentive motivation immediately followed by a test for receptivity and proceptive behaviors. Two weeks later they were tested in the light/dark choice procedure, and after another 2 weeks they were subjected to a test in a brightly lit open field. Finally, the females were given free access to a running wheel for 88h. The females were treated with estradiol benzoate (EB), 18 or 1.5μg/kg, in randomized order 52h before each test except the running wheel. In that experiment, they were given EB 48h after introduction into the wheel cage. They were given progesterone, 1mg/rat, about 4h before all tests, except the running wheel. The shRNA reduced the number of ERα with 83%. Females with few ERα in the MPOA showed increased lordosis quotient after the 1.5μg/kg dose of EB. There was no effect on proceptive behaviors or on rejections. When given the 18μg/kg EB dose, there was no difference between females with few preoptic ERα and controls. In the test for sexual incentive motivation, females with few preoptic ERα approached the castrated male incentive more than controls, regardless of EB dose. They also moved a shorter distance. In the light/dark choice test as well as in the open field, females with few ERα in the MPOA showed signs of reduced fear/anxiety, since they spent more time in the light part of the dark/light box and in the center of the open field. Finally, the data from the running wheel showed that females with few preoptic ERα failed to show enhanced activity after treatment with EB. These data show that the preoptic ERα inhibits lordosis in females with an intermediate level of receptivity while it fails to do so in fully receptive females. The ERα in the MPOA seems to be necessary for selective approach to a sexual incentive. Finally, activation of this receptor appears to have anxiogenic effects in the procedures employed here. A hypothesis for how all these actions of the preoptic ERα contributes to efficient reproductive behavior is outlined. Copyright © 2012 Elsevier B.V. All rights reserved.

The Influence of Rotations on Match Running Performance in Female Australian Football Midfielders.

PubMed

Black, Georgia M; Gabbett, Tim J; Johnston, Richard D; Naughton, Geraldine; Cole, Michael H; Dawson, Brian

2018-04-01

With female Australian football (AF) gaining popularity, understanding match demands is becoming increasingly important. The aim of this study was to compare running performances of rotated and whole-quarter state-level female AF players during match quarters. Twenty-two state-level female AF midfielders wore Global Positioning System units during 14 games to evaluate activity profiles. The Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1) was used as a measure of high-intensity running ability. Data were categorized into whole quarter, rotation bout 1, and rotation bout 2 before being further divided into quartiles. Players were separated into high- or low-Yo-Yo IR1 groups using a median split based on their Yo-Yo IR1 performance. Short (4-6 min), moderate (6-12 min), and long (12-18 min) on-field bout activity profiles were compared with whole-quarter players. High Yo-Yo IR1 performance allowed players to cover greater relative distances (ES = 0.57-0.88) and high-speed distances (ES = 0.57-0.86) during rotations. No differences were reported between Yo-Yo IR1 groups when players were required to play whole quarters (ES ≤ 0.26, likelihood ≤64%). Players who were on field for short to moderate durations exhibited greater activity profiles than whole-quarter players. Superior high-speed running ability results in a greater activity profile than for players who possess lower high-speed running ability. The findings also highlight the importance of short to moderate (4-12 min) rotation periods and may be used to increase high-intensity running performance within quarters in female AF players.

The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression.

PubMed

Bjørnebekk, Astrid; Mathé, Aleksander A; Brené, Stefan

2010-07-01

One hypothesis of depression is that it is caused by reduced neuronal plasticity including hippocampal neurogenesis. In this study, we compared the effects of three long-term antidepressant treatments: escitalopram, voluntary running, and their combination on hippocampal cell proliferation, NPY and the NPY-Y1 receptor mRNAs, targets assumed to be important for hippocampal plasticity and mood disorders. An animal model of depression, the Flinders Sensitive Line (FSL) rat, was used and female rats were chosen because the majority of the depressed population is females. We investigated if these treatments were correlated to immobility, swimming, and climbing behaviors, which are associated with an overall, serotonergic-like and noradrenergic-like antidepressant response, in the Porsolt swim test (PST). Interestingly, while escitalopram, running and their combination increased the number of hippocampal BrdU immunoreactive cells, the antidepressant-like effect was only detected in the running group and the group with access both to running wheel and escitalopram. Hippocampal NPY mRNA and the NPY-Y1 receptor mRNA were elevated by running and the combined treatment. Moreover, correlations were detected between NPY mRNA levels and climbing and cell proliferation and NPY-Y1 receptor mRNA levels and swimming. Our results suggest that increased cell proliferation is not necessarily associated with an antidepressant effect. However, treatments that were associated with an antidepressant-like effect did regulate hippocampal levels of mRNAs encoding NPY and/or the NPY-Y1 receptor and support the notion that NPY can stimulate cell proliferation and induce an antidepressant-like response. Copyright 2009 Wiley-Liss, Inc.

Loss of Cdk5 function in the nucleus accumbens decreases wheel running and may mediate age-related declines in voluntary physical activity.

PubMed

Ruegsegger, Gregory N; Toedebusch, Ryan G; Childs, Thomas E; Grigsby, Kolter B; Booth, Frank W

2017-01-01

Physical inactivity, which drastically increases with advancing age, is associated with numerous chronic diseases. The nucleus accumbens (the pleasure and reward 'hub' in the brain) influences wheel running behaviour in rodents. RNA-sequencing and subsequent bioinformatics analysis led us to hypothesize a potential relationship between the regulation of dendritic spine density, the molecules involved in synaptic transmission, and age-related reductions in wheel running. Upon completion of follow-up studies, we developed the working model that synaptic plasticity in the nucleus accumbens is central to age-related changes in voluntary running. Testing this hypothesis, inhibition of Cdk5 (comprising a molecule central to the processes described above) in the nucleus accumbens reduced wheel running. The results of the present study show that reductions in synaptic transmission and Cdk5 function are related to decreases in voluntary running behaviour and provide guidance for understanding the neural mechanisms that underlie age-dependent reductions in the motivation to be physically active. Increases in age are often associated with reduced levels of physical activity, which, in turn, associates with the development of numerous chronic diseases. We aimed to assess molecular differences in the nucleus accumbens (NAc) (a specific brain nucleus postulated to influence rewarding behaviour) with respect to wheel running and sedentary female Wistar rats at 8 and 14 weeks of age. RNA-sequencing was used to interrogate transcriptomic changes between 8- and 14-week-old wheel running rats, and select transcripts were later analysed by quantitative RT-PCR in age-matched sedentary rats. Voluntary wheel running was greatest at 8 weeks and had significantly decreased by 12 weeks. From 619 differentially expressed mRNAs, bioinformatics suggested that cAMP-mediated signalling, dopamine- and cAMP-regulated neuronal phosphoprotein of 32 kDa feedback, and synaptic plasticity were greater in 8- vs. 14-week-old rats. In depth analysis of these networks showed significant (∼20-30%; P < 0.05) decreases in cell adhesion molecule (Cadm)4 and p39 mRNAs, as well as their proteins from 8 to 14 weeks of age in running and sedentary rats. Furthermore, Cadm4, cyclin-dependent kinase 5 (Cdk5) and p39 mRNAs were significantly correlated with voluntary running distance. Analysis of dendritic spine density in the NAc showed that wheel access increased spine density (P < 0.001), whereas spine density was lower in 14- vs. 8-week-old sedentary rats (P = 0.03). Intriguingly, intra-NAc injection of the Cdk5 inhibitor roscovitine, dose-dependently decreased wheel running. Collectively, these experiments suggest that an age-dependent loss in synaptic function and Cdk5/p39 activity in the NAc may be partially responsible for age-related declines in voluntary running behaviour. © 2016 The Authors. The Journal of Physiology © 2016 The Physiological Society.

Loss of Cdk5 function in the nucleus accumbens decreases wheel running and may mediate age‐related declines in voluntary physical activity

PubMed Central

Ruegsegger, Gregory N.; Toedebusch, Ryan G.; Childs, Thomas E.; Grigsby, Kolter B.

2016-01-01

Key points Physical inactivity, which drastically increases with advancing age, is associated with numerous chronic diseases.The nucleus accumbens (the pleasure and reward ‘hub’ in the brain) influences wheel running behaviour in rodents.RNA‐sequencing and subsequent bioinformatics analysis led us to hypothesize a potential relationship between the regulation of dendritic spine density, the molecules involved in synaptic transmission, and age‐related reductions in wheel running. Upon completion of follow‐up studies, we developed the working model that synaptic plasticity in the nucleus accumbens is central to age‐related changes in voluntary running.Testing this hypothesis, inhibition of Cdk5 (comprising a molecule central to the processes described above) in the nucleus accumbens reduced wheel running.The results of the present study show that reductions in synaptic transmission and Cdk5 function are related to decreases in voluntary running behaviour and provide guidance for understanding the neural mechanisms that underlie age‐dependent reductions in the motivation to be physically active. Abstract Increases in age are often associated with reduced levels of physical activity, which, in turn, associates with the development of numerous chronic diseases. We aimed to assess molecular differences in the nucleus accumbens (NAc) (a specific brain nucleus postulated to influence rewarding behaviour) with respect to wheel running and sedentary female Wistar rats at 8 and 14 weeks of age. RNA‐sequencing was used to interrogate transcriptomic changes between 8‐ and 14‐week‐old wheel running rats, and select transcripts were later analysed by quantitative RT‐PCR in age‐matched sedentary rats. Voluntary wheel running was greatest at 8 weeks and had significantly decreased by 12 weeks. From 619 differentially expressed mRNAs, bioinformatics suggested that cAMP‐mediated signalling, dopamine‐ and cAMP‐regulated neuronal phosphoprotein of 32 kDa feedback, and synaptic plasticity were greater in 8‐ vs. 14‐week‐old rats. In depth analysis of these networks showed significant (∼20–30%; P < 0.05) decreases in cell adhesion molecule (Cadm)4 and p39 mRNAs, as well as their proteins from 8 to 14 weeks of age in running and sedentary rats. Furthermore, Cadm4, cyclin‐dependent kinase 5 (Cdk5) and p39 mRNAs were significantly correlated with voluntary running distance. Analysis of dendritic spine density in the NAc showed that wheel access increased spine density (P < 0.001), whereas spine density was lower in 14‐ vs. 8‐week‐old sedentary rats (P = 0.03). Intriguingly, intra‐NAc injection of the Cdk5 inhibitor roscovitine, dose‐dependently decreased wheel running. Collectively, these experiments suggest that an age‐dependent loss in synaptic function and Cdk5/p39 activity in the NAc may be partially responsible for age‐related declines in voluntary running behaviour. PMID:27461471

Adaptive Integration of Nonsmooth Dynamical Systems

DTIC Science & Technology

2017-10-11

controlled time stepping method to interactively design running robots. [1] John Shepherd, Samuel Zapolsky, and Evan M. Drumwright, “Fast multi-body...software like this to test software running on my robots. Started working in simulation after attempting to use software like this to test software... running on my robots. The libraries that produce these beautiful results have failed at simulating robotic manipulation. Postulate: It is easier to

Effects of changing speed on knee and ankle joint load during walking and running.

PubMed

de David, Ana Cristina; Carpes, Felipe Pivetta; Stefanyshyn, Darren

2015-01-01

Joint moments can be used as an indicator of joint loading and have potential application for sports performance and injury prevention. The effects of changing walking and running speeds on joint moments for the different planes of motion still are debatable. Here, we compared knee and ankle moments during walking and running at different speeds. Data were collected from 11 recreational male runners to determine knee and ankle joint moments during different conditions. Conditions include walking at a comfortable speed (self-selected pacing), fast walking (fastest speed possible), slow running (speed corresponding to 30% slower than running) and running (at 4 m · s(-1) ± 10%). A different joint moment pattern was observed between walking and running. We observed a general increase in joint load for sagittal and frontal planes as speed increased, while the effects of speed were not clear in the transverse plane moments. Although differences tend to be more pronounced when gait changed from walking to running, the peak moments, in general, increased when speed increased from comfortable walking to fast walking and from slow running to running mainly in the sagittal and frontal planes. Knee flexion moment was higher in walking than in running due to larger knee extension. Results suggest caution when recommending walking over running in an attempt to reduce knee joint loading. The different effects of speed increments during walking and running should be considered with regard to the prevention of injuries and for rehabilitation purposes.

77 FR 49485 - Agency Information Collection Activities: Proposed Information Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... requirement for national banks and Federal savings associations titled, ``Company-Run Annual Stress Test... proposed information collection: Title: Company-Run Annual Stress Test Reporting Template and Documentation... stress tests \\2\\ and requires the primary financial regulatory agency \\3\\ of those financial companies to...

77 FR 66663 - Agency Information Collection Activities: Proposed Information Collection; Submission for OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-06

... titled, ``Company-Run Annual Stress Test Reporting Template and Documentation for Covered Institutions... review and clearance. Company-Run Annual Stress Test Reporting Template and Documentation for Covered... savings associations, to conduct annual stress tests \\2\\ and requires the primary financial regulatory...

Compensations for increased rotational inertia during human cutting turns.

PubMed

Qiao, Mu; Brown, Brian; Jindrich, Devin L

2014-02-01

Locomotion in a complex environment is often not steady state, but unsteady locomotion (stability and maneuverability) is not well understood. We investigated the strategies used by humans to perform sidestep cutting turns when running. Previous studies have argued that because humans have small yaw rotational moments of inertia relative to body mass, deceleratory forces in the initial velocity direction that occur during the turning step, or 'braking' forces, could function to prevent body over-rotation during turns. We tested this hypothesis by increasing body rotational inertia and testing whether braking forces during stance decreased. We recorded ground reaction force and body kinematics from seven participants performing 45 deg sidestep cutting turns and straight running at five levels of body rotational inertia, with increases up to fourfold. Contrary to our prediction, braking forces remained consistent at different rotational inertias, facilitated by anticipatory changes to body rotational speed. Increasing inertia revealed that the opposing effects of several turning parameters, including rotation due to symmetrical anterior-posterior forces, result in a system that can compensate for fourfold changes in rotational inertia with less than 50% changes to rotational velocity. These results suggest that in submaximal effort turning, legged systems may be robust to changes in morphological parameters, and that compensations can involve relatively minor adjustments between steps to change initial stance conditions.

Compensations for increased rotational inertia during human cutting turns

PubMed Central

Qiao, Mu; Brown, Brian; Jindrich, Devin L.

2014-01-01

Locomotion in a complex environment is often not steady state, but unsteady locomotion (stability and maneuverability) is not well understood. We investigated the strategies used by humans to perform sidestep cutting turns when running. Previous studies have argued that because humans have small yaw rotational moments of inertia relative to body mass, deceleratory forces in the initial velocity direction that occur during the turning step, or ‘braking’ forces, could function to prevent body over-rotation during turns. We tested this hypothesis by increasing body rotational inertia and testing whether braking forces during stance decreased. We recorded ground reaction force and body kinematics from seven participants performing 45 deg sidestep cutting turns and straight running at five levels of body rotational inertia, with increases up to fourfold. Contrary to our prediction, braking forces remained consistent at different rotational inertias, facilitated by anticipatory changes to body rotational speed. Increasing inertia revealed that the opposing effects of several turning parameters, including rotation due to symmetrical anterior–posterior forces, result in a system that can compensate for fourfold changes in rotational inertia with less than 50% changes to rotational velocity. These results suggest that in submaximal effort turning, legged systems may be robust to changes in morphological parameters, and that compensations can involve relatively minor adjustments between steps to change initial stance conditions. PMID:24115061

Analysis of Flexible Car Body of Straddle Monorail Vehicle

NASA Astrophysics Data System (ADS)

Zhong, Yuanmu

2018-03-01

Based on the finite element model of straddle monorail vehicle, a rigid-flexible coupling dynamic model considering vehicle body’s flexibility is established. The influence of vertical stiffness and vertical damping of the running wheel on the modal parameters of the car body is analyzed. The effect of flexible car body on modal parameters and vehicle ride quality is also studied. The results show that when the vertical stiffness of running wheel is less than 1 MN / m, the car body bounce and pitch frequency increase with the increasing of the vertical stiffness of the running wheel, when the running wheel vertical stiffness is 1MN / m or more, car body bounce and pitch frequency remained unchanged; When the vertical stiffness of the running wheel is below 1.8 MN / m, the vehicle body bounce and pitch damping ratio increase with the increasing of the vertical stiffness of the running wheel; When the running wheel vertical stiffness is 1.8MN / m or more, the car body bounce and pitch damping ratio remained unchanged; The running wheel vertical damping on the car body bounce and pitch frequency has no effect; Car body bounce and pitch damping ratio increase with the increasing of the vertical damping of the running wheel. The flexibility of the car body has no effect on the modal parameters of the car, which will improve the vehicle ride quality index.

Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratory.

PubMed

Pham, Therese M; Brené, Stefan; Baumans, Vera

2005-01-01

Physical cage enrichment--exercise devices for rodents in the laboratory--often includes running wheels. This study compared responses of mice in enriched physical and social conditions and in standard social conditions to wheel running, individual housing, and open-field test. The study divided into 6 groups, 48 female BALB/c mice group housed in enriched and standard conditions. On alternate days, the study exposed 2 groups to individual running wheel cages. It intermittently separated from their cage mates and housed individually 2 groups with no running wheels; 2 control groups remained in enriched or standard condition cages. There were no significant differences between enriched and standard group housed mice in alternate days' wheel running. Over time, enriched, group housed mice ran less. Both groups responded similarly to individual housing. In open-field test, mice exposed to individual housing without running wheel moved more and faster than wheel running and home cage control mice. They have lower body weights than group housed and wheel running mice. Intermittent withdrawal of individual housing affects the animals more than other commodities. Wheel running normalizes some effects of intermittent separation from the enriched, social home cage.

40 CFR 86.340-79 - Gasoline-fueled engine dynamometer test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Observe pre-test procedures; § 86.339; (3) Start cooling system; (4) Start engine and operate in... be 5 minutes ±30 seconds. Sample flow may begin during the warm-up; (5) Read and record all pre-test... test run. 86.340-79 Section 86.340-79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

40 CFR 86.340-79 - Gasoline-fueled engine dynamometer test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Observe pre-test procedures; § 86.339; (3) Start cooling system; (4) Start engine and operate in... be 5 minutes ±30 seconds. Sample flow may begin during the warm-up; (5) Read and record all pre-test... test run. 86.340-79 Section 86.340-79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

40 CFR 86.341-79 - Diesel engine dynamometer test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

... and sample probes as required; (2) Observe pre-test procedure, § 86.339; (3) Read and record the... observed torque for the rated and intermediate speeds; (8) Read and record all pre-test data specified in... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Diesel engine dynamometer test run. 86...

40 CFR 86.341-79 - Diesel engine dynamometer test run.

Code of Federal Regulations, 2013 CFR

2013-07-01

... and sample probes as required; (2) Observe pre-test procedure, § 86.339; (3) Read and record the... observed torque for the rated and intermediate speeds; (8) Read and record all pre-test data specified in... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Diesel engine dynamometer test run. 86...

40 CFR 86.341-79 - Diesel engine dynamometer test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and sample probes as required; (2) Observe pre-test procedure, § 86.339; (3) Read and record the... observed torque for the rated and intermediate speeds; (8) Read and record all pre-test data specified in... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Diesel engine dynamometer test run. 86...

40 CFR 86.340-79 - Gasoline-fueled engine dynamometer test run.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Observe pre-test procedures; § 86.339; (3) Start cooling system; (4) Start engine and operate in... be 5 minutes ±30 seconds. Sample flow may begin during the warm-up; (5) Read and record all pre-test... test run. 86.340-79 Section 86.340-79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

40 CFR 86.340-79 - Gasoline-fueled engine dynamometer test run.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Observe pre-test procedures; § 86.339; (3) Start cooling system; (4) Start engine and operate in... be 5 minutes ±30 seconds. Sample flow may begin during the warm-up; (5) Read and record all pre-test... test run. 86.340-79 Section 86.340-79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

40 CFR 86.341-79 - Diesel engine dynamometer test run.

Code of Federal Regulations, 2011 CFR

2011-07-01

... and sample probes as required; (2) Observe pre-test procedure, § 86.339; (3) Read and record the... observed torque for the rated and intermediate speeds; (8) Read and record all pre-test data specified in... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Diesel engine dynamometer test run. 86...

Physical Fitness Test Battery for Mentally Retarded Children (Trainable and Educable).

ERIC Educational Resources Information Center

Fait, Hollis F.

A physical fitness test battery for educable and trainable mentally handicapped children is presented. Instructions are given for administering the test; descriptions are given of the seven test items, including the 25 yard run, bent arm hang, leg lift, static balance, thrust, and 300 yard run-walk. Rationale for the items and factors in…

A Primer-Test Centered Equating Method for Setting Cut-Off Scores

ERIC Educational Resources Information Center

Zhu, Weimo; Plowman, Sharon Ann; Park, Youngsik

2010-01-01

This study evaluated the use of a new primary field test method based on test equating to address inconsistent classification among field tests. We analyzed students' information on the Progressive Aerobic Cardiovascular Endurance Run (PACER), mile run (MR), and VO[subscript 2]max from three data sets (college: n = 94; middle school: n = 39;…

40 CFR 63.5993 - What performance tests and other procedures must I use?

Code of Federal Regulations, 2010 CFR

2010-07-01

... CATEGORIES National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing General... specified in § 63.7(e)(1). (d) You must conduct three separate test runs for each performance test required... test run must last at least 1 hour. (e) If you are complying with the emission limitations using a...

Home cage wheel running is an objective and clinically relevant method to assess inflammatory pain in male and female rats

PubMed Central

Kandasamy, Ram; Calsbeek, Jonas J.; Morgan, Michael M.

2016-01-01

Background The assessment of nociception in preclinical studies is undergoing a transformation from pain-evoked to pain-depressed tests to more closely mimic the effects of clinical pain. Many inflammatory pain-depressed behaviors (reward seeking, locomotion) have been examined, but these tests are limited because of confounds such as stress and difficulties in quantifying behavior. New Method The present study evaluates home cage wheel running as an objective method to assess the magnitude and duration of inflammatory pain in male and female rats. Results Injection of Complete Freund’s Adjuvant (CFA) into the right hindpaw to induce inflammatory pain almost completely inhibited wheel running for 2 days in males and females. Wheel running gradually returned to baseline levels within 12 days despite persistent mechanical hypersensitivity (von Frey test). Comparison with Existing Methods Continuously monitoring home cage wheel running improves on previous studies examining inflammatory pain-depressed wheel running because it is more sensitive to noxious stimuli, avoids the stress of removing the rat from its cage for testing, and provides a complete analysis of the time course for changes in nociception. Conclusions The present data indicate that home cage wheel running is a clinically relevant method to assess inflammatory pain in the rat. The decrease in activity caused by inflammatory pain and subsequent gradual recovery mimics the changes in activity caused by pain in humans. The tendency for pain-depressed wheel running to be greater in female than male rats is consistent with the tendency for women to be at greater risk of chronic pain than men. PMID:26891874

Excessive eccentric exercise leads to transitory hypothalamic inflammation, which may contribute to the low body weight gain and food intake in overtrained mice.

PubMed

Pereira, B C; da Rocha, A L; Pauli, J R; Ropelle, E R; de Souza, C T; Cintra, D E; Sant'Ana, M R; da Silva, A S R

2015-12-17

Low body weight gain and food intake are related to exhaustive training and overtraining; however, the molecular mechanisms responsible for these alterations remain unknown. The main aim of this study was to evaluate the effects of running overtraining (OT) protocols performed downhill, uphill and without inclination on the inflammatory pathway in the mouse hypothalamus. The rodents were randomized into the control (C), overtrained by downhill running (OTR/down), overtrained by uphill running (OTR/up) and overtrained by running without inclination (OTR) groups. The body weights and food intake were recorded daily. The incremental load, exhaustive, rotarod and grip force tests were used to measure performance. At 36 h after the grip force test was performed at the end of OT protocols (i.e., week eight) and/or after a 2-week total recovery period (i.e., week 10), the hypothalamus and gastrocnemius were extracted for immunoblotting analysis. In addition, the serum was used to determine cytokine and leptin concentrations. From week 0 to week 8, the OTR/down group exhibited decreased body weight and food intake, and the OTR/up group increased their food intake. At week 10, the OTR/down group exhibited increased body weight, while the OTR group decreased their food intake. The OTR/down group exhibited increased IL-1beta, IL-6, TNF-alpha, pSAPK/JNK and SOCS3 levels at week eight. The OTR/down, OTR/up and OTR groups exhibited increased IL-10 levels at week 10. The OTR/up group displayed increased pJAK2 levels at week eight. While the OTR/down group exhibited increased IL-1beta levels, the OTR/down and OTR/up groups exhibited increased IL-6 and TNF-alpha levels, but decreased IL-10 levels in the gastrocnemius at week eight. The three OT protocols increased the IL-1beta and IL-6 levels, but only the OTR/down and OTR/up groups had increased TNF-alpha levels in serum at week eight. The serum leptin levels were lower for the OTR group compared with the CT group at week eight. In conclusion, the OTR/down protocol induced transitory hypothalamic inflammation with concomitant reductions in the body weight and food intake. After the 2-week total recovery period, the OTR/down group had reversed the hypothalamic inflammation, with the concomitant normalization of the body weight and food intake. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

Maintaining vigorous activity attenuates 7-yr weight gain in 8340 runners.

PubMed

Williams, Paul T

2007-05-01

Body weight generally increases with aging in Western societies. Although training studies show that exercise produces acute weight loss, it is unclear whether the long-term maintenance of vigorous exercise attenuates the trajectory of age-related weight gain. Specifically, prior studies have not tested whether the maintenance of physical activity, in the absence of any change in activity, prevents weight gain. Prospective study of 6119 male and 2221 female runners whose running distances changed < 5 km x wk(-1) between baseline and follow-up surveys 7 yr later. On average, men who maintained modest (0-23 km x wk(-1)), intermediate (24-47 km x wk(-1)), or prolonged running distances (> or = 48 km x wk(-1)) all gained weight through age 64; however, those who maintained > or = 48 km x wk(-1) had one half the average annual weight gain of those who maintained < 24 km x wk(-1). For example, between the ages of 35 and 44 in men and 30 and 39 yr in women, those who maintained < 24 km x wk(-1) gained, on average, 2.1 and 2.9 kg more per decade than those averaging > 48 km x wk(-1). Age-related weight gain, and its attenuation by maintained exercise, were both greater in younger than in older men. Men's gains in waist circumference with age, and its attenuation by maintaining running, were the same in older and younger men. Regardless of age, women increased their body weight, waist circumference, and hip circumference over time, and these measurements were attenuated in proportion to their maintained running distance. In both sexes, running disproportionately prevented more extreme increases in weight. As they aged, men and women gained less weight in proportion to their levels of sustained vigorous activity. This long-term beneficial effect is in addition to the acute weight loss that occurs with increased activity.

Long-Term Exercise Is a Potent Trigger for ΔFosB Induction in the Hippocampus along the dorso–ventral Axis

PubMed Central

Nishijima, Takeshi; Kawakami, Masashi; Kita, Ichiro

2013-01-01

Physical exercise improves multiple aspects of hippocampal function. In line with the notion that neuronal activity is key to promoting neuronal functions, previous literature has consistently demonstrated that acute bouts of exercise evoke neuronal activation in the hippocampus. Repeated activating stimuli lead to an accumulation of the transcription factor ΔFosB, which mediates long-term neural plasticity. In this study, we tested the hypothesis that long-term voluntary wheel running induces ΔFosB expression in the hippocampus, and examined any potential region-specific effects within the hippocampal subfields along the dorso–ventral axis. Male C57BL/6 mice were housed with or without a running wheel for 4 weeks. Long-term wheel running significantly increased FosB/ΔFosB immunoreactivity in all hippocampal regions measured (i.e., in the DG, CA1, and CA3 subfields of both the dorsal and ventral hippocampus). Results confirmed that wheel running induced region-specific expression of FosB/ΔFosB immunoreactivity in the cortex, suggesting that the uniform increase in FosB/ΔFosB within the hippocampus is not a non-specific consequence of running. Western blot data indicated that the increased hippocampal FosB/ΔFosB immunoreactivity was primarily due to increased ΔFosB. These results suggest that long-term physical exercise is a potent trigger for ΔFosB induction throughout the entire hippocampus, which would explain why exercise can improve both dorsal and ventral hippocampus-dependent functions. Interestingly, we found that FosB/ΔFosB expression in the DG was positively correlated with the number of doublecortin-immunoreactive (i.e., immature) neurons. Although the mechanisms by which ΔFosB mediates exercise-induced neurogenesis are still uncertain, these data imply that exercise-induced neurogenesis is at least activity dependent. Taken together, our current results suggest that ΔFosB is a new molecular target involved in regulating exercise-induced hippocampal plasticity. PMID:24282574

13-Foot Diameter Hydrogen Tank Tested in the K-Site Test Chamber

NASA Image and Video Library

1967-09-21

A 13-foot diameter mounted inside the large test chamber at the Cryogenic Propellant Tank, or K-Site, at National Aeronautics and Space Administration’s (NASA) Plum Brook Station. The 25-foot test chamber and 20-foot access door were designed to test liquid hydrogen fuel tanks up to 18 feet in diameter in conditions that simulated launches and spaceflight. Shakers were installed to test the effects of launch vibration on the tanks and their insulation. The K Site chamber was also equipped with cold walls that could be cooled with either liquid nitrogen or liquid hydrogen and vacuum pumps that could reduce pressure levels to 10-8 torr. This 13-foot tank passed its initial acceptance tests in K-Site on August 24, 1966. Delays in the modification of the tank postponed further tests of the tank until May 1967. Four pressure hold tests and expulsion runs were made in May using gaseous hydrogen or gaseous helium at 300R and 520R. In June a straight pipe injector test was run and two pressure effect tests at 35 and 75psi. Propellant slosh tests were successfully run in August. This photograph was taken the day after the program’s final runs on September 12, 1967.

78 FR 51272 - Agency Information Collection Activities: Revision of an Approved Information Collection; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

... requirement for national banks and Federal savings associations titled, ``Company-Run Annual Stress Test...://www.occ.treas.gov/tools-forms/forms/bank-operations/stress-test-reporting.html ). SUPPLEMENTARY...: Title: Company-Run Annual Stress Test Reporting Template and Documentation for Covered Institutions with...

40 CFR 1045.501 - How do I run a valid emission test?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false How do I run a valid emission test? 1045.501 Section 1045.501 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Test...

40 CFR 1045.501 - How do I run a valid emission test?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false How do I run a valid emission test? 1045.501 Section 1045.501 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Test...

40 CFR 1045.501 - How do I run a valid emission test?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I run a valid emission test? 1045.501 Section 1045.501 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Test...

40 CFR 1045.501 - How do I run a valid emission test?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false How do I run a valid emission test? 1045.501 Section 1045.501 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Test...

40 CFR 1045.501 - How do I run a valid emission test?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false How do I run a valid emission test? 1045.501 Section 1045.501 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Test...

75 FR 44948 - California State Motor Vehicle Pollution Control Standards; Within-the-Scope Determination for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... amendments to its evaporative emission test procedures, four-wheel drive dynamometer provisions, and vehicle... manufacturer has certified vehicles using an alternative running loss test procedure, CARB may conduct... manufacturer's approved alternative running loss test procedure; (3) provide manufacturers an option to use an...

Experimental evaluation of tool run-out in micro milling

NASA Astrophysics Data System (ADS)

Attanasio, Aldo; Ceretti, Elisabetta

2018-05-01

This paper deals with micro milling cutting process focusing the attention on tool run-out measurement. In fact, among the effects of the scale reduction from macro to micro (i.e., size effects) tool run-out plays an important role. This research is aimed at developing an easy and reliable method to measure tool run-out in micro milling based on experimental tests and an analytical model. From an Industry 4.0 perspective this measuring strategy can be integrated into an adaptive system for controlling cutting forces, with the objective of improving the production quality, the process stability, reducing at the same time the tool wear and the machining costs. The proposed procedure estimates the tool run-out parameters from the tool diameter, the channel width, and the phase angle between the cutting edges. The cutting edge phase measurement is based on the force signal analysis. The developed procedure has been tested on data coming from micro milling experimental tests performed on a Ti6Al4V sample. The results showed that the developed procedure can be successfully used for tool run-out estimation.

NASA CF6 jet engine diagnostics program: Long-term CF6-6D low-pressure turbine deterioration

NASA Technical Reports Server (NTRS)

Smith, J. J.

1979-01-01

Back-to-back performance tests were run on seven airline low pressure turbine (LPT) modules and four new CF6-6D modules. Back-to-back test cell runs, in which an airline LPT module was directly compared to a new production module, were included. The resulting change, measured in fuel burn, equaled the level of LPT module deterioration. Three of the LPT modules were analytically inspected followed by a back-to-back test cell run to evaluate current refurbishment techniques.

Muscular strategy shift in human running: dependence of running speed on hip and ankle muscle performance.

PubMed

Dorn, Tim W; Schache, Anthony G; Pandy, Marcus G

2012-06-01

Humans run faster by increasing a combination of stride length and stride frequency. In slow and medium-paced running, stride length is increased by exerting larger support forces during ground contact, whereas in fast running and sprinting, stride frequency is increased by swinging the legs more rapidly through the air. Many studies have investigated the mechanics of human running, yet little is known about how the individual leg muscles accelerate the joints and centre of mass during this task. The aim of this study was to describe and explain the synergistic actions of the individual leg muscles over a wide range of running speeds, from slow running to maximal sprinting. Experimental gait data from nine subjects were combined with a detailed computer model of the musculoskeletal system to determine the forces developed by the leg muscles at different running speeds. For speeds up to 7 m s(-1), the ankle plantarflexors, soleus and gastrocnemius, contributed most significantly to vertical support forces and hence increases in stride length. At speeds greater than 7 m s(-1), these muscles shortened at relatively high velocities and had less time to generate the forces needed for support. Thus, above 7 m s(-1), the strategy used to increase running speed shifted to the goal of increasing stride frequency. The hip muscles, primarily the iliopsoas, gluteus maximus and hamstrings, achieved this goal by accelerating the hip and knee joints more vigorously during swing. These findings provide insight into the strategies used by the leg muscles to maximise running performance and have implications for the design of athletic training programs.

Reagent and labor cost optimization through automation of fluorescence in situ hybridization (FISH) with the VP 2000: an Italian case study.

PubMed

Zanatta, Lucia; Valori, Laura; Cappelletto, Eleonora; Pozzebon, Maria Elena; Pavan, Elisabetta; Dei Tos, Angelo Paolo; Merkle, Dennis

2015-02-01

In the modern molecular diagnostic laboratory, cost considerations are of paramount importance. Automation of complex molecular assays not only allows a laboratory to accommodate higher test volumes and throughput but also has a considerable impact on the cost of testing from the perspective of reagent costs, as well as hands-on time for skilled laboratory personnel. The following study tracked the cost of labor (hands-on time) and reagents for fluorescence in situ hybridization (FISH) testing in a routine, high-volume pathology and cytogenetics laboratory in Treviso, Italy, over a 2-y period (2011-2013). The laboratory automated FISH testing with the VP 2000 Processor, a deparaffinization, pretreatment, and special staining instrument produced by Abbott Molecular, and compared hands-on time and reagent costs to manual FISH testing. The results indicated significant cost and time saving when automating FISH with VP 2000 when more than six FISH tests were run per week. At 12 FISH assays per week, an approximate total cost reduction of 55% was observed. When running 46 FISH specimens per week, the cost saving increased to 89% versus manual testing. The results demonstrate that the VP 2000 processor can significantly reduce the cost of FISH testing in diagnostic laboratories. © 2014 Society for Laboratory Automation and Screening.

Development and Prevention of Running-Related Osteoarthritis.

PubMed

Ni, Guo-Xin

2016-01-01

Studies investigating the effect of running on risk for developing osteoarthritis at weight-bearing joints have reported with conflicting results. Generally, moderate-level running is not likely detrimental to joint health. However, many factors may be associated with the increased risk of developing osteoarthritis in runners. Factors often implicated in the development of osteoarthritis comprise those that increase joint vulnerability and those which increase joint loading. It is therefore suggested that running has different effects on different people. Efforts should be made to identify those with joint vulnerability and joint loading, and measures should be taken to have those factors and/or their running programs modified to run safely. Further investigations are needed to examine the effect of running on joint health under different conditions to confirm the association between exposure to risk factors and development of osteoarthritis, as well as to validate the effectiveness of measures for preventing running-related osteoarthritis.

Assessing locomotor skills development in childhood using wearable inertial sensor devices: the running paradigm.

PubMed

Masci, Ilaria; Vannozzi, Giuseppe; Bergamini, Elena; Pesce, Caterina; Getchell, Nancy; Cappozzo, Aurelio

2013-04-01

Objective quantitative evaluation of motor skill development is of increasing importance to carefully drive physical exercise programs in childhood. Running is a fundamental motor skill humans adopt to accomplish locomotion, which is linked to physical activity levels, although the assessment is traditionally carried out using qualitative evaluation tests. The present study aimed at investigating the feasibility of using inertial sensors to quantify developmental differences in the running pattern of young children. Qualitative and quantitative assessment tools were adopted to identify a skill-sensitive set of biomechanical parameters for running and to further our understanding of the factors that determine progression to skilled running performance. Running performances of 54 children between the ages of 2 and 12 years were submitted to both qualitative and quantitative analysis, the former using sequences of developmental level, the latter estimating temporal and kinematic parameters from inertial sensor measurements. Discriminant analysis with running developmental level as dependent variable allowed to identify a set of temporal and kinematic parameters, within those obtained with the sensor, that best classified children into the qualitative developmental levels (accuracy higher than 67%). Multivariate analysis of variance with the quantitative parameters as dependent variables allowed to identify whether and which specific parameters or parameter subsets were differentially sensitive to specific transitions between contiguous developmental levels. The findings showed that different sets of temporal and kinematic parameters are able to tap all steps of the transitional process in running skill described through qualitative observation and can be prospectively used for applied diagnostic and sport training purposes. Copyright © 2012 Elsevier B.V. All rights reserved.

Initial test results using the GEOS-3 engineering model altimeter

NASA Technical Reports Server (NTRS)

Hayne, G. S.; Clary, J. B.

1977-01-01

Data from a series of experimental tests run on the engineering model of the GEOS 3 radar altimeter using the Test and Measurement System (TAMS) designed for preflight testing of the radar altimeter are presented. These tests were conducted as a means of preparing and checking out a detailed test procedure to be used in running similar tests on the GEOS 3 protoflight model altimeter systems. The test procedures and results are also included.

Relationship between percentages of heart rate reserve and oxygen uptake reserve during cycling and running: a validation study.

PubMed

Guimarães, Giovanna C; Farinatti, Paulo T V; Midgley, Adrian W; Vasconcellos, Fabrício; Vigário, Patrícia; Cunha, Felipe A

2017-06-22

The present study investigated the relationship between percentages of heart rate reserve (%HRR) and oxygen uptake reserve (%VO2R) during a cardiopulmonary exercise test (CPET) and discrete bouts of isocaloric cycling and treadmill running. Thirty men visited the laboratory three times for anthropometrical and resting VO2 assessments, and perform cycling and running CPETs. Ten men visited the laboratory twice more to investigate the validity of the %HRR-%VO2R relationships during isocaloric bouts of cycling and running at 75% VO2R with energy expenditures of 400 kcals. The %HRR was significantly higher than the %VO2R during both CPETs at all exercise intensities (P < 0.001). During isocaloric exercise bouts, mean %HRR-%VO2R differences of 6.5% and 7.0% were observed for cycling and running, respectively (P = 0.007 to P < 0.001). The %HRR and %VO2R increased over time (P < 0.001), the rate of which was influenced by exercise modality (P < 0.001). On average, heart rate was 5 (P = 0.007) and 8 (P < 0.001) beats·min higher than predicted from the second energy expenditure quartile for cycling and running, respectively; however, observed VO2 was lower than predicted during all quartiles for cycling, and the first quartile for running. Consequently, time to achieve the target energy expenditure was greater than predicted (P < 0.01). In conclusion, the %HRR-%VO2R relationship observed during CPET data did not accurately transpose to prolonged isocaloric bouts of cycling and running. Additionally, power outputs and speeds defined by the ACSM equations for cycling and running, respectively, overestimated VO2 and energy expenditure.

Rediscovering a Stream in Danville, Kentucky: The Clark Run Corridor and Trails Project.

ERIC Educational Resources Information Center

Bright, Debra

1998-01-01

In Danville, Kentucky, the community cooperated in converting a neglected stream into a walking trail and park network, resulting in increased community pride, environmental awareness, community revitalization, and public-private cooperation. The local middle school regularly tests the water, and the local college's annual clean-up party earned an…

The Effect of Three Message Organization Variables Upon Listener Comprehension.

ERIC Educational Resources Information Center

Johnson, Arlee W.

Public speaking texts urge speakers to organize their message in order to increase their audience's comprehension of it. Tests were run to determine if listeners understand better when three message organization variables are employed in a speech: explicit statement of the central idea, explicit statement of the main points, and transitions before…

Relationship between Running Speed and Cognitive Processes in Orienteering: Two Empirical Studies.

ERIC Educational Resources Information Center

Cheshikhina, Valentina V.

1993-01-01

Fourteen qualified orienteers completed a stepwise increased treadmill velocity test in which controls had to be transferred from a master map. Orienteering accuracy was greatest at the anaerobic threshold speed. In a second study, 17 orienteers performed arithmetic tasks before and after a treadmill workout. Performance was significantly better…

Soy protein is beneficial but high-fat diet and voluntary running are detrimental to bone structure in mice.

PubMed

Yan, Lin; Graef, George L; Nielsen, Forrest H; Johnson, LuAnn K; Cao, Jay

2015-06-01

Physical activity and soy protein isolate (SPI) augmentation have been reported to be beneficial for bone health. We hypothesized that combining voluntary running and SPI intake would alleviate detrimental changes in bone induced by a high-fat diet. A 2 × 2 × 2 experiment was designed with diets containing 16% or 45% of energy as corn oil and 20% SPI or casein fed to sedentary or running male C57BL/6 mice for 14 weeks. Distal femurs were assessed for microstructural changes. The high-fat diet significantly decreased trabecular number (Tb.N) and bone mineral density (BMD) and increased trabecular separation (Tb.Sp). Soy protein instead of casein, regardless of fat content, in the diet significantly increased bone volume fraction, Tb.N, connectivity density, and BMD and decreased Tb.Sp. Voluntary running, regardless of fat content, significantly decreased bone volume fraction, Tb.N, connectivity density, and BMD and increased Tb.Sp. The high-fat diet significantly decreased osteocalcin and increased tartrate-resistant acid phosphatase 5b (TRAP 5b) concentrations in plasma. Plasma concentrations of osteocalcin were increased by both SPI and running. Running alleviated the increase in TRAP 5b induced by the high-fat diet. These findings demonstrate that a high-fat diet is deleterious, and SPI is beneficial to trabecular bone properties. The deleterious effect of voluntary running on trabecular structural characteristics indicates that there may be a maximal threshold of running beyond which beneficial effects cease and detrimental effects occur. Increases in plasma osteocalcin and decreases in plasma TRAP 5b in running mice suggest that a compensatory response occurs to counteract the detrimental effects of excessive running. Published by Elsevier Inc.

Rolling-element fatigue life with traction fluids and automatic transmission fluid in a high-speed rolling-contact rig

NASA Technical Reports Server (NTRS)

Parker, R. J.; Nahm, A. H.; Loewenthal, S. H.

1982-01-01

Rolling-element fatigue tests were run in standard and high-speed rolling-contact rigs at bar speeds from 5000 to 50,000 rpm to determine the effects of speed and lubricant film parameter on rolling-element fatigue life. AISI 52100 test bars were tested at a maximum Hertz stress of 4.83 GPa (700,000 psi) with three traction fluids and an automatic transmission fluid. Rolling-element fatigue life increased with speed, with the greatest increases occurring from 10,000 to 50,000 rpm. The life data tended to follow published life-versus-lubricant-film-parameter data up to a film parameter of approximately 3.

Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen.

PubMed

Werme, M; Thorén, P; Olson, L; Brené, S

2000-08-01

Physical activities such as long-distance running can be habit forming and associated with a sense of well-being to a degree that justifies comparison with drug-induced addictive behaviours. To understand molecular similarities and dissimilarities controlling these behaviours in humans we compared the effects of running in running wheels to the effects of chronic cocaine or morphine administration on mRNA levels in brain reward pathways in the inbred Fischer and Lewis rat strains. These strains are both inbred from the Sprague-Dawley strain; Lewis rats display a higher preference towards addictive drugs and running than do Fischer rats. After chronic cocaine or running a similar increase of dynorphin mRNA in medial caudate putamen was found in the Lewis rat, suggesting common neuronal adaptations in this brain region to both cocaine and running. Fischer and Lewis rats both responded to cocaine with increased dynorphin mRNA levels in medial caudate putamen. However, only Lewis rats increased dynorphin mRNA after running, possibly reflecting the much higher degree of running by the Lewis strain as compared to the Fischer strain. Moreover, the running-induced upregulation of dynorphin mRNA was blocked by the opioid receptor antagonist naloxone. We suggest that running increases dynorphin mRNA by a mechanism that involves endogenous opioids. The voluntary wheel-running model in rats might be used to study natural reward and compulsive behaviours and possibly also to screen candidate drugs for treatment of compulsive disorders.

Analysis Of Rearfoot Motion In Running Shoes

NASA Astrophysics Data System (ADS)

Cooper, Les

1986-12-01

In order to produce better shoes that cushion athletes from the high impact forces of running and still provide stability to the foot it is essential to have a method of quickly and reliably evaluating the performance of prototype shoes. The analysis of rear-foot motion requires the use of film or video recordings of test subjects running on a treadmill. Specific points on the subject are tracked to give a measure of inversion or eversion of the heel. This paper describes the testing procedure and its application to running shoe design. A comparison of film and video systems is also discussed.

Voluntary resistance running wheel activity pattern and skeletal muscle growth in rats.

PubMed

Legerlotz, Kirsten; Elliott, Bradley; Guillemin, Bernard; Smith, Heather K

2008-06-01

The aims of this study were to characterize the pattern of voluntary activity of young rats in response to resistance loading on running wheels and to determine the effects of the activity on the growth of six limb skeletal muscles. Male Sprague-Dawley rats (4 weeks old) were housed individually with a resistance running wheel (R-RUN, n = 7) or a conventional free-spinning running wheel (F-RUN, n = 6) or without a wheel, as non-running control animals (CON, n = 6). The torque required to move the wheel in the R-RUN group was progressively increased, and the activity (velocity, distance and duration of each bout) of the two running wheel groups was recorded continuously for 45 days. The R-RUN group performed many more, shorter and faster bouts of running than the F-RUN group, yet the mean daily distance was not different between the F-RUN (1.3 +/- 0.2 km) and R-RUN group (1.4 +/- 0.6 km). Only the R-RUN resulted in a significantly (P < 0.05) enhanced muscle wet mass, relative to the increase in body mass, of the plantaris (23%) and vastus lateralis muscle (17%), and the plantaris muscle fibre cross-sectional area, compared with CON. Both F-RUN and R-RUN led to a significantly greater wet mass relative to increase in body mass and muscle fibre cross-sectional area in the soleus muscle compared with CON. We conclude that the pattern of voluntary activity on a resistance running wheel differs from that on a free-spinning running wheel and provides a suitable model to induce physiological muscle hypertrophy in rats.

Setting Time Limits on Tests

ERIC Educational Resources Information Center

van der Linden, Wim J.

2011-01-01

It is shown how the time limit on a test can be set to control the probability of a test taker running out of time before completing it. The probability is derived from the item parameters in the lognormal model for response times. Examples of curves representing the probability of running out of time on a test with given parameters as a function…

9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

Influence of the Lower Jaw Position on the Running Pattern.

PubMed

Maurer, Christian; Stief, Felix; Jonas, Alexander; Kovac, Andrej; Groneberg, David Alexander; Meurer, Andrea; Ohlendorf, Daniela

2015-01-01

The effects of manipulated dental occlusion on body posture has been investigated quite often and discussed controversially in the literature. Far less attention has been paid to the influence of dental occlusion position on human movement. If human movement was analysed, it was mostly while walking and not while running. This study was therefore designed to identify the effect of lower jaw positions on running behaviour according to different dental occlusion positions. Twenty healthy young recreational runners (mean age = 33.9±5.8 years) participated in this study. Kinematic data were collected using an eight-camera Vicon motion capture system (VICON Motion Systems, Oxford, UK). Subjects were consecutively prepared with four different dental occlusion conditions in random order and performed five running trials per test condition on a level walkway with their preferred running shoes. Vector based pattern recognition methods, in particular cluster analysis and support vector machines (SVM) were used for movement pattern identification. Subjects exhibited unique movement patterns leading to 18 clusters for the 20 subjects. No overall classification of the splint condition could be observed. Within individual subjects different running patterns could be identified for the four splint conditions. The splint conditions lead to a more symmetrical running pattern than the control condition. The influence of an occlusal splint on running pattern can be confirmed in this study. Wearing a splint increases the symmetry of the running pattern. A more symmetrical running pattern might help to reduce the risk of injuries or help in performance. The change of the movement pattern between the neutral condition and any of the three splint conditions was significant within subjects but not across subjects. Therefore the dental splint has a measureable influence on the running pattern of subjects, however subjects individuality has to be considered when choosing the optimal splint condition for a specific subject.

Lower limb muscle activity during forefoot and rearfoot strike running techniques.

PubMed

Landreneau, Lindsey L; Watts, Kayla; Heitzman, Jill E; Childers, W Lee

2014-12-01

Distance running offers a method to improve fitness but also has a risk of lower limb overuse injuries. Foot strike technique has been suggested as a method to alter loading of the lower limb and possibly minimize injury risk. However, there is a dearth of information regarding neuromuscular response to variations in running techniques. The purpose of this investigation was to compare the EMG activity that occurs during FFS running and RFS running, focusing on the biceps femoris, semitendenosis, rectus femoris, vastus medialis oblique, tibialis anterior (TA), medial head of gastrocnemeus (MGas), lateral head of gastrocnemius (LGas), and soleus. healthy adults (6 male, 8 female; age, 24.2 ± 0.8 years, height 170.1 ± 7.8 cm; mass 69.8 ±10.9 kg; Body Mass Index 24.1 ± 3.0 kg·m2) participated in the study. All participants performed a RFS and FFS running trial at 8.85 kph. A 3D motion capture system was used to collect kinematic data and electromyography was used to define muscle activity. Two-tailed paired t-tests were used to examine differences in outcomes between RFS and FFS conditions. The ankle was significantly more plantarflexed during FFS running (p = .0001) but there were no significant differences in knee and hip angles (p = .618 & .200, respectively). There was significantly less activity in tibialis anterior (TA) (p < .0001) and greater activity in the MGas (p= .020) during FFS running. The LGas and soleus did not change activity (p = .437 & .490, respectively). FFS running demonstrated lower muscular activity in the TA and increased activation in the MGas. FFS and RFS running have the potential to off-load injury prone tissues by changing between techniques. However, future studies will be necessary to establish more direct mechanistic connections between running technique and injury.

Effect of whey protein hydrolysate on performance and recovery of top-class orienteering runners.

PubMed

Hansen, Mette; Bangsbo, Jens; Jensen, Jørgen; Bibby, Bo Martin; Madsen, Klavs

2015-04-01

This trial aimed to examine the effect of whey protein hydrolysate intake before and after exercise sessions on endurance performance and recovery in elite orienteers during a training camp. Eighteen elite orienteers participated in a randomized controlled intervention trial during a 1-week training camp (13 exercise sessions). Half of the runners (PRO-CHO) ingested a protein drink before (0.3 g kg(-1)) and a protein-carbohydrate drink after (0.3 g protein kg(-1) and 1 g carbohydrate kg(-1)) each exercise session. The others ingested energy and time-matched carbohydrate drinks (CHO). A 4-km run-test with 20 control points was performed before and on the last day of the intervention. Blood and saliva were obtained in the mornings, before and after run-tests, and after the last training session. During the intervention, questionnaires were fulfilled regarding psychological sense of performance capacity and motivation. PRO-CHO and not CHO improved performance in the 4-km run-test (interaction p < .05). An increase in serum creatine kinase was observed during the week, which was greater in CHO than PRO-CHO (interaction p < .01). Lactate dehydrogenase (p < .001) and cortisol (p = .057) increased during the week, but the change did not differ between groups. Reduction in sense of performance capacity during the intervention was greater in CHO (p < .05) than PRO-CHO. In conclusion, ingestion of whey protein hydrolysate before and after each exercise session improves performance and reduces markers of muscle damage during a strenuous 1-week training camp. The results indicate that protein supplementation in conjunction with each exercise session facilitates the recovery from strenuous training in elite orienteers.

Oxidative Capacity and Fatigability in Run Trained Malignant Hyperthermia Susceptible Mice

PubMed Central

Rouviere, Clement; Corona, Benjamin T.; Ingalls, Christopher P.

2011-01-01

Introduction The purpose of this study was to test the hypothesis that Malignant Hyperthermia model mice (RyR1Y522S/wt) are more vulnerable to exercise-induced muscle injury and fatigability and adapt less to run training. Methods Following 6 weeks of voluntary wheel running, we measured anterior crural muscle fatigability, muscle injury, and cytochrome oxidase (COX) and citrate synthase (CS). Results Although RyR1Y522S/wt mice ran without experiencing MH episodes, they ran 42% less distance than wild type (WT) mice. Muscles from WT mice exhibited increased fatigue resistance and COX content after training. Muscles from RyR1Y522S/wt mice demonstrated no significant change in fatigability or COX and CS after training. However, muscles from RyR1Y522S/wt mice displayed less intrinsic fatigability and greater COX/CS content and muscle damage than WT mice. Discussion RyR1Y522S/wt mice can run without experiencing rhabdomyolysis, and their inability to adapt to training appears to stem from intrinsic enhancement of mitochondrial enzymes and fatigue resistance. PMID:22431093

Oxidative capacity and fatigability in run-trained malignant hyperthermia-susceptible mice.

PubMed

Rouviere, Clement; Corona, Benjamin T; Ingalls, Christopher P

2012-04-01

The purpose of this study was to test the hypothesis that malignant hyperthermia model mice (RyR1Y522S/wt) are more vulnerable to exercise-induced muscle injury and fatigability and adapt less to run training. After 6 weeks of voluntary wheel running, we measured anterior crural muscle fatigability, muscle injury, and cytochrome oxidase (COX) and citrate synthase (CS). Although RyR1Y522S/wt mice ran without undergoing MH episodes, they ran 42% less distance than wild-type (WT) mice. Muscles from WT mice exhibited increased fatigue resistance and COX content after training. Muscles from RyR1Y522S/wt mice demonstrated no significant change in fatigability or COX and CS after training. However, muscles from RyR1Y522S/wt mice displayed less intrinsic fatigability and greater COX/CS content and muscle damage than WT mice. RyR1Y522S/wt mice can run without having rhabdomyolysis, and their inability to adapt to training appears to stem from intrinsic enhancement of mitochondrial enzymes and fatigue resistance. Copyright © 2012 Wiley Periodicals, Inc.

Shock Transmission and Fatigue in Human Running.

PubMed

Verbitsky, Oleg; Mizrahi, Joseph; Voloshin, Arkady; Treiger, July; Isakov, Eli

1998-08-01

The goal of this research was to analyze the effects of fatigue on the shock waves generated by foot strike. Twenty-two subjects were instrumented with an externally attached, lightweight accelerometer placed over the tibial tuberosity. The subjects ran on a treadmill for 30 min at a speed near their anaerobic threshold. Fatigue was established when the end-tidal CO 2 pressure decreased. The results indicated that approximately half of the subjects reached the fatigue state toward the end of the test. Whenever fatigue occurred, the peak acceleration was found to increase. It was thus concluded that there is a clear association between fatigue and increased heel strike-induced shock waves. These results have a significant implication for the etiology of running injuries, since shock wave attenuation has been previously reported to play an important role in preventing such injuries.

Even One Is Too Much: Sole Presence of One of the Risk Factors Overweight, Lack of Exercise, and Smoking Reduces Physical Fitness of Young Soldiers.

PubMed

Leyk, Dieter; Witzki, Alexander; Willi, Gorges; Rohde, Ulrich; Rüther, Thomas

2015-11-01

Health and physical fitness are key factors for soldiers. Increased sedentary military work, significant sitting periods during commuting and leisure time, and unhealthy dietary habits have caused a considerable increase in the number of physically unfit soldiers. Even worse, the adoption of harmful lifestyle habits occurs increasingly earlier in life. The aim of this cross-sectional study was (a) to determine the physical fitness of young male soldiers and (b) to investigate the association between physical fitness and both the presence and frequency of the health risk factors overweight, smoking, and lack of exercise. A total of 4,553 volunteers aged 18-25 years performed the Basis Fitness Test consisting of the 3 disciplines agility (11 × 10 m shuttle sprint), strength (flexed-arm hang), and endurance (1,000-m run). The presence and frequency of risk factors were determined by means of anthropometric measures (body mass index, waist circumference) and questionnaire data. The portion of soldiers without risk factors decreased from 49.4% (18-year-olds) to 16.4% for 25-year-olds. Persons without risk factors completed the agility test in 41.1 ± 3.7 seconds, flexed-arm hang in 60.1 ± 19.7 seconds, and 1,000-m run in 235 ± 32 seconds. Physical performance in all dimensions tested (agility, strength, endurance) notably deteriorated with the sole presence of one of the risk factors overweight, smoking, and lack of exercise. Any further risk factor led to further fitness decreases (p < 0.001). Mean performances of soldiers with 3 risk factors were 46.7 ± 4.1 seconds (11 × 10 m shuttle sprint), 27.6 ± 6.4 seconds (flexed-arm hang), and 298 ± 45 seconds (1,000-m run). Impacts of unhealthy lifestyles and significant losses in physical fitness are already visible in young male soldiers. Armed Forces must intensify their efforts to maintain health and performance of their soldiers.

Investigation of package sealing using organic adhesives

NASA Technical Reports Server (NTRS)

Perkins, K. L.; Licari, J. J.

1977-01-01

A systematic study was performed to evaluate the suitability of adhesives for sealing hybrid packages. Selected adhesives were screened on the basis of their ability to seal gold-plated Kovar butterfly-type packages that retain their seal integrity after individual exposures to increasingly severe temperature-humidity environments. Tests were also run using thermal shock, temperature cycling, mechanical shock and temperature aging. The four best adhesives were determined and further tested in a 60 C/98% RH environment and continuously monitored in regard to moisture content. Results are given, however, none of the tested adhesives passed all the tests.

40 CFR 86.1237-85 - Dynamometer runs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Dynamometer runs. 86.1237-85 Section... Methanol-Fueled Heavy-Duty Vehicles § 86.1237-85 Dynamometer runs. (a) The vehicle shall be either driven... the diurnal loss test and beginning of the hot soak preparation run shall not exceed 3 minutes, and...

A Review of Safety Practices and Safety Training for the Explosives Field

DTIC Science & Technology

1985-02-01

reworking. This was discovered when an impact test was run on the received material and a "GO" occurred. If the received material bad been handled as...exist, small quantities of the explosive or explosive mixture should -be subjected to- sensitivity tests (including at least spark sensitivity, impact ...increases more energy is put into the nix which must be considered with respect to blending speeds and tolerances in equip- ment and temperatures. Also

The Effect of Increasing Inertia upon Vertical Ground Reaction Forces during Locomotion

NASA Technical Reports Server (NTRS)

DeWitt, John K.; Hagan, R. Donald; Cromwell, Ronita L.

2007-01-01

The addition of inertia to exercising astronauts could increase ground reaction forces and potentially provide a greater health benefit. However, conflicting results have been reported regarding the adaptations to additional mass (inertia) without additional net weight (gravitational force) during locomotion. We examined the effect of increasing inertia while maintaining net gravitational force on vertical ground reaction forces and kinematics during walking and running. Vertical ground reaction force was measured for ten healthy adults (5 male/5 female) during walking (1.34 m/s) and running (3.13 m/s) using a force-measuring treadmill. Subjects completed locomotion at normal weight and mass, and at 10, 20, 30, and 40% of added inertial force. The added gravitational force was relieved with overhead suspension, so that the net force between the subject and treadmill at rest remained equal to 100% body weight. Peak vertical impact forces and loading rates increased with increased inertia during walking, and decreased during running. As inertia increased, peak vertical propulsive forces decreased during walking and did not change during running. Stride time increased during walking and running, and contact time increased during running. Vertical ground reaction force production and adaptations in gait kinematics were different between walking and running. The increased inertial forces were utilized independently from gravitational forces by the motor control system when determining coordination strategies.

Fundamental movement skills testing in children with cerebral palsy.

PubMed

Capio, Catherine M; Sit, Cindy H P; Abernethy, Bruce

2011-01-01

To examine the inter-rater reliability and comparative validity of product-oriented and process-oriented measures of fundamental movement skills among children with cerebral palsy (CP). In total, 30 children with CP aged 6 to 14 years (Mean = 9.83, SD = 2.5) and classified in Gross Motor Function Classification System (GMFCS) levels I-III performed tasks of catching, throwing, kicking, horizontal jumping and running. Process-oriented assessment was undertaken using a number of components of the Test of Gross Motor Development (TGMD-2), while product-oriented assessment included measures of time taken, distance covered and number of successful task completions. Cohen's kappa, Spearman's rank correlation coefficient and tests to compare correlated correlation coefficients were performed. Very good inter-rater reliability was found. Process-oriented measures for running and jumping had significant associations with GMFCS, as did seven product-oriented measures for catching, throwing, kicking, running and jumping. Product-oriented measures of catching, kicking and running had stronger associations with GMFCS than the corresponding process-oriented measures. Findings support the validity of process-oriented measures for running and jumping and of product-oriented measures of catching, throwing, kicking, running and jumping. However, product-oriented measures for catching, kicking and running appear to have stronger associations with functional abilities of children with CP, and are thus recommended for use in rehabilitation processes.

Experimental Evaluation of Cermet Turbine Stator Blades for Use at Elevated Gas Temperatures

NASA Technical Reports Server (NTRS)

Chiarito, Patrick T.; Johnston, James R.

1959-01-01

The suitability of cermets for turbine stator blades of a modified turbojet engine was determined at an average turbine-inlet-gas temperature of 2000 F. Such an increase in temperature would yield a premium in thrust from a service engine. Because the cermet blades require no cooling, all the available compressor bleed air could be used to cool a turbine made from conventional ductile alloys. Cermet blades were first run in 100-hour endurance tests at normal gas temperatures in order to evaluate two methods for mounting them. The elevated gas-temperature test was then run using the method of support considered best for high-temperature operation. After 52 hours at 2000 F, one of the group of four cermet blades fractured probably because of end loads resulting from thermal distortion of the spacer band of the nozzle diaphragm. Improved design of a service engine would preclude this cause of premature failure.

Lean Six Sigma in Health Care: Improving Utilization and Reducing Waste.

PubMed

Almorsy, Lamia; Khalifa, Mohamed

2016-01-01

Healthcare costs have been increasing worldwide mainly due to over utilization of resources. The savings potentially achievable from systematic, comprehensive, and cooperative reduction in waste are far higher than from more direct and blunter cuts in care and coverage. At King Faisal Specialist Hospital and Research Center inappropriate and over utilization of the glucose test strips used for whole blood glucose determination using glucometers was observed. The hospital implemented a project to improve its utilization. Using the Six Sigma DMAIC approach (Define, Measure, Analyze, Improve and Control), an efficient practice was put in place including updating the related internal policies and procedures and the proper implementation of an effective users' training and competency check off program. That resulted in decreasing the unnecessary Quality Control (QC) runs from 13% to 4%, decreasing the failed QC runs from 14% to 7%, lowering the QC to patient testing ratio from 24/76 to 19/81.

The Effect of Increasing Mass upon Locomotion

NASA Technical Reports Server (NTRS)

DeWitt, John; Hagan, Donald

2007-01-01

The purpose of this investigation was to determine if increasing body mass while maintaining bodyweight would affect ground reaction forces and joint kinetics during walking and running. It was hypothesized that performing gait with increased mass while maintaining body weight would result in greater ground reaction forces, and would affect the net joint torques and work at the ankle, knee and hip when compared to gait with normal mass and bodyweight. Vertical ground reaction force was measured for ten subjects (5M/5F) during walking (1.34 m/s) and running (3.13 m/s) on a treadmill. Subjects completed one minute of locomotion at normal mass and bodyweight and at four added mass (AM) conditions (10%, 20%, 30% and 40% of body mass) in random order. Three-dimensional joint position data were collected via videography. Walking and running were analyzed separately. The addition of mass resulted in several effects. Peak impact forces and loading rates increased during walking, but decreased during running. Peak propulsive forces decreased during walking and did not change during running. Stride time increased and hip extensor angular impulse and positive work increased as mass was added for both styles of locomotion. Work increased at a greater rate during running than walking. The adaptations to additional mass that occur during walking are different than during running. Increasing mass during exercise in microgravity may be beneficial to increasing ground reaction forces during walking and strengthening hip musculature during both walking and running. Future study in true microgravity is required to determine if the adaptations found would be similar in a weightless environment.

Experimental study of the effects of secondary air on the emissions and stability of a lean premixed combustor

NASA Technical Reports Server (NTRS)

Roffe, G.; Raman, R. S. V.

1981-01-01

Tests were run using a perforated plate flameholder with a relatively short attached recirculation zone and a vee gutter flameholder with a relatively long attached recirculation zone. Combustor streamlines were traced in cold flow tests at ambient pressure. The amount of secondary air entrainment in the recirculation zones of the flameholders was determined by tracer gas testing at cold flow ambient pressure conditions. Combustion tests were caried out at entrance conditions of 0.5 MPa/630K and emission of NOx, CO and unburned hydrocarbons were measured along with lean stability and flashback limits. The degree of entrainment increases as dilution air injection decreases. Flashback appears to be a function of overall equivalence ratio and resistance to flashback increases with increasing combustor entrance velocity. Lean stability limit appears to be a function of both primary zone and flameholder recirculation zone equivalence ratios and resistance to lean blowout increases with increasing combustor entrance velocity.

Functional Movement Screen for Predicting Running Injuries in 18- to 24-Year-Old Competitive Male Runners.

PubMed

Hotta, Takayuki; Nishiguchi, Shu; Fukutani, Naoto; Tashiro, Yuto; Adachi, Daiki; Morino, Saori; Shirooka, Hidehiko; Nozaki, Yuma; Hirata, Hinako; Yamaguchi, Moe; Aoyama, Tomoki

2015-10-01

The purpose of this study was to investigate whether the functional movement screen (FMS) could predict running injuries in competitive runners. Eighty-four competitive male runners (average age = 20.0 ± 1.1 years) participated. Each subject performed the FMS, which consisted of 7 movement tests (each score range: 0-3, total score range: 0-21), during the preseason. The incidence of running injuries (time lost because of injury ≤ 4 weeks) was investigated through a follow-up survey during the 6-month season. Mann-Whitney U-tests were used to investigate which movement tests were significantly associated with running injuries. The receiver-operator characteristic (ROC) analysis was used to determine the cutoff. The mean FMS composite score was 14.1 ± 2.3. The ROC analysis determined the cutoff at 14/15 (sensitivity = 0.73, specificity = 0.54), suggesting that the composite score had a low predictability for running injuries. However, the total scores (0-6) from the deep squat (DS) and active straight leg raise (ASLR) tests (DS and ASLR), which were significant with the U-test, had relatively high predictability at the cutoff of 3/4 (sensitivity = 0.73, specificity = 0.74). Furthermore, the multivariate logistic regression analysis revealed that the DS and ASLR scores of ≤3 significantly influenced the incidence of running injuries after adjusting for subjects' characteristics (odds ratio = 9.7, 95% confidence interval = 2.1-44.4). Thus, the current study identified the DS and ASLR score as a more effective method than the composite score to screen the risk of running injuries in competitive male runners.

Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo.

PubMed

Lee-Young, R S; Ayala, J E; Fueger, P T; Mayes, W H; Kang, L; Wasserman, D H

2011-07-01

Skeletal muscle AMP-activated protein kinase (AMPK)α2 activity is impaired in obese, insulin-resistant individuals during exercise. We determined whether this defect contributes to the metabolic dysregulation and reduced exercise capacity observed in the obese state. C57BL/6J wild-type (WT) mice and/or mice expressing a kinase dead AMPKα2 subunit in skeletal muscle (α2-KD) were fed chow or high-fat (HF) diets from 3 to 16 weeks of age. At 15 weeks, mice performed an exercise stress test to determine exercise capacity. In WT mice, muscle glucose uptake and skeletal muscle AMPKα2 activity was assessed in chronically catheterized mice (carotid artery/jugular vein) at 16 weeks. In a separate study, HF-fed WT and α2-KD mice performed 5 weeks of exercise training (from 15 to 20 weeks of age) to test whether AMPKα2 is necessary to restore work tolerance. HF-fed WT mice had reduced exercise tolerance during an exercise stress test, and an attenuation in muscle glucose uptake and AMPKα2 activity during a single bout of exercise (P<0.05 versus chow). In chow-fed α2-KD mice, running speed and time were impaired ∼45 and ∼55%, respectively (P<0.05 versus WT chow); HF feeding further reduced running time ∼25% (P<0.05 versus α2-KD chow). In response to 5 weeks of exercise training, HF-fed WT and α2-KD mice increased maximum running speed ∼35% (P<0.05 versus pre-training) and maintained body weight at pre-training levels, whereas body weight increased in untrained HF WT and α2-KD mice. Exercise training restored running speed to levels seen in healthy, chow-fed mice. HF feeding impairs AMPKα2 activity in skeletal muscle during exercise in vivo. Although this defect directly contributes to reduced exercise capacity, findings in HF-fed α2-KD mice show that AMPKα2-independent mechanisms are also involved. Importantly, α2-KD mice on a HF-fed diet adapt to regular exercise by increasing exercise tolerance, demonstrating that this adaptation is independent of skeletal muscle AMPKα2 activity.

Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind, randomised, controlled trial.

PubMed

Paulsen, Gøran; Cumming, Kristoffer T; Holden, Geir; Hallén, Jostein; Rønnestad, Bent Ronny; Sveen, Ole; Skaug, Arne; Paur, Ingvild; Bastani, Nasser E; Østgaard, Hege Nymo; Buer, Charlotte; Midttun, Magnus; Freuchen, Fredrik; Wiig, Havard; Ulseth, Elisabeth Tallaksen; Garthe, Ina; Blomhoff, Rune; Benestad, Haakon B; Raastad, Truls

2014-04-15

In this double-blind, randomised, controlled trial, we investigated the effects of vitamin C and E supplementation on endurance training adaptations in humans. Fifty-four young men and women were randomly allocated to receive either 1000 mg of vitamin C and 235 mg of vitamin E or a placebo daily for 11 weeks. During supplementation, the participants completed an endurance training programme consisting of three to four sessions per week (primarily of running), divided into high-intensity interval sessions [4-6 × 4-6 min; >90% of maximal heart rate (HRmax)] and steady state continuous sessions (30-60 min; 70-90% of HRmax). Maximal oxygen uptake (VO2 max ), submaximal running and a 20 m shuttle run test were assessed and blood samples and muscle biopsies were collected, before and after the intervention. Participants in the vitamin C and E group increased their VO2 max (mean ± s.d.: 8 ± 5%) and performance in the 20 m shuttle test (10 ± 11%) to the same degree as those in the placebo group (mean ± s.d.: 8 ± 5% and 14 ± 17%, respectively). However, the mitochondrial marker cytochrome c oxidase subunit IV (COX4) and cytosolic peroxisome proliferator-activated receptor-γ coactivator 1 α (PGC-1α) increased in the m. vastus lateralis in the placebo group by 59 ± 97% and 19 ± 51%, respectively, but not in the vitamin C and E group (COX4: -13 ± 54%; PGC-1α: -13 ± 29%; P ≤ 0.03, between groups). Furthermore, mRNA levels of CDC42 and mitogen-activated protein kinase 1 (MAPK1) in the trained muscle were lower in the vitamin C and E group than in the placebo group (P ≤ 0.05). Daily vitamin C and E supplementation attenuated increases in markers of mitochondrial biogenesis following endurance training. However, no clear interactions were detected for improvements in VO2 max and running performance. Consequently, vitamin C and E supplementation hampered cellular adaptations in the exercised muscles, and although this did not translate to the performance tests applied in this study, we advocate caution when considering antioxidant supplementation combined with endurance exercise.

Do Generous Welfare States Generate Efficiency Gains Which Counterbalance Short Run Losses? Testing Downside Risk Theory with Economic Panel Data for the U.S., Germany and the Netherlands

ERIC Educational Resources Information Center

Headey, Bruce; Muffels, Ruud

2008-01-01

The purpose of the paper is to assess the theory that the downside risk insurance provided by more generous welfare states generates long run efficiency gains, which counterbalance the short run efficiency losses caused by work disincentives in these states (Feldstein 1974, 1976; Sinn 1995, 1996). Testing downside risk theory requires long term…

Effects of alcohol on attention orienting and dual-task performance during simulated driving: an event-related potential study.

PubMed

Wester, Anne E; Verster, Joris C; Volkerts, Edmund R; Böcker, Koen B E; Kenemans, J Leon

2010-09-01

Driving is a complex task and is susceptible to inattention and distraction. Moreover, alcohol has a detrimental effect on driving performance, possibly due to alcohol-induced attention deficits. The aim of the present study was to assess the effects of alcohol on simulated driving performance and attention orienting and allocation, as assessed by event-related potentials (ERPs). Thirty-two participants completed two test runs in the Divided Attention Steering Simulator (DASS) with blood alcohol concentrations (BACs) of 0.00%, 0.02%, 0.05%, 0.08% and 0.10%. Sixteen participants performed the second DASS test run with a passive auditory oddball to assess alcohol effects on involuntary attention shifting. Sixteen other participants performed the second DASS test run with an active auditory oddball to assess alcohol effects on dual-task performance and active attention allocation. Dose-dependent impairments were found for reaction times, the number of misses and steering error, even more so in dual-task conditions, especially in the active oddball group. ERP amplitudes to novel irrelevant events were also attenuated in a dose-dependent manner. The P3b amplitude to deviant target stimuli decreased with blood alcohol concentration only in the dual-task condition. It is concluded that alcohol increases distractibility and interference from secondary task stimuli, as well as reduces attentional capacity and dual-task integrality.

Self-motivated and stress-response performance assays in mice are age-dependent.

PubMed

Ge, Xuan; Ciol, Marcia A; Pettan-Brewer, Christina; Goh, Jorming; Rabinovitch, Peter; Ladiges, Warren

2017-05-01

Chronic health conditions of the elderly lead to limitations in physical activity with disability, anxiety, and increased need for medical care and assisted living conditions. Physical performance tests are used to screen for pending loss of mobility and can serve as endpoints to monitor the effectiveness of intervention measures. Since limited mobility is associated with the physical and mental health of a person, evaluation of this in preclinical aging studies in mice will provide a translational approach for testing new intervention strategies. We assessed physiological parameters in 4, 12, 20 and 28month old C57BL/6 and CB6F1 male mice using a rotating rod, a free running wheel, and a photo beam activity field, designed to determine changes in coordinated walking ability, self-motivated running distance, and anxiety response to a novel environment, respectively. Older mice showed decreased coordinated walking times and decreased running distances, predictive of physical performance ability and motivation in the elderly. Changes in both lateral and vertical movements were observed in a novel cage environment suggesting different levels of anxiety. Because the genetic background of the two mouse strains influenced test results in an age-dependent manner, it is imperative to recognize that diverse genetic backgrounds in mice may yield different data in preclinical studies and would need to be interpreted individually for translational applications. Copyright © 2017 Elsevier Inc. All rights reserved.