Influence of inland aerosol loading on the monsoon over Indian subcontinent

NASA Astrophysics Data System (ADS)

Satyanarayana, M.; Krishnakumar, V.; Mahadevan Pillai, V. P.; Radhakrishnan, S. R.; Raghunath, K.

2008-12-01

The monsoon water cycle is the lifeline to over 60% of the world's population. The study on the behavioral change of Indian monsoon due to aerosol loading will help for the better understanding of Indian Monsoon. Aerosol system influences the atmosphere in two ways; it affects directly the radiation budget and indirectly provides condensation nuclei required for the clouds. The precipitation of the clouds in the monsoon season depends on the microphysical properties of the clouds. The effect of aerosol on cirrus clouds is being looked into through this work as an effort to study the role of aerosol on Indian Monsoon. The microphysical properties of high altitude clouds were obtained from the ground based lidar experiments at a low latitude station in the Indian subcontinent. Measurements during the Indian monsoon period from the inland station National Atmospheric Research Laboratory (NARL) Gadanki (13.5_ N, 79.2_ E), Tirupati, India were used for the investigation. The depolarization characteristics of the cirrus clouds were measured and the correlation between the depolarization and the precipitation characteristics were studied. The results obtained over a period of one year from January 1998 to December 1998 were presented.

Aridification driven diversification of fan-throated lizards from the Indian subcontinent.

PubMed

Deepak, V; Karanth, Praveen

2018-03-01

The establishment of monsoon climate and the consequent aridification has been one of the most important climate change episodes in the Indian subcontinent. However, little is known about how these events might have shaped the diversification patterns among the widely distributed taxa. Fan-throated lizards (FTL) (Genus: Sitana, Sarada) are widespread, diurnal and restricted to the semi-arid zones of the Indian subcontinent. We sampled FTL in 107 localities across its range. We used molecular species delimitation method and delineated 15 species including six putative species. Thirteen of them were distinguishable based on morphology but two sister species were indistinguishable and have minor overlaps in distribution. Five fossils were used to calibrate and date the phylogeny. Diversification of fan-throated lizards lineage started ~18 mya and higher lineage diversification was observed after 11 my. The initial diversification corresponds to the time when monsoon climate was established and the latter was a period of intensification of monsoon and initiation of aridification. Thirteen out of the fifteen FTL species delimited are from Peninsular India; this is probably due to the landscape heterogeneity in this region. The species poor sister genus Otocryptis is paraphyletic and probably represents relict lineages which are now confined to forested areas. Thus, the seasonality led changes in habitat, from forests to open habitats appear to have driven diversification of fan-throated lizards. Copyright © 2017 Elsevier Inc. All rights reserved.

Geographic patterns of networks derived from extreme precipitation over the Indian subcontinent

NASA Astrophysics Data System (ADS)

Stolbova, Veronika; Bookhagen, Bodo; Marwan, Norbert; Kurths, Juergen

2014-05-01

Complex networks (CN) and event synchronization (ES) methods have been applied to study a number of climate phenomena such as Indian Summer Monsoon (ISM), South-American Monsoon, and African Monsoon. These methods proved to be powerful tools to infer interdependencies in climate dynamics between geographical sites, spatial structures, and key regions of the considered climate phenomenon. Here, we use these methods to study the spatial temporal variability of the extreme rainfall over the Indian subcontinent, in order to filter the data by coarse-graining the network, and to identify geographic patterns that are signature features (spatial signatures) of the ISM. We find four main geographic patterns of networks derived from extreme precipitation over the Indian subcontinent using up-to-date satellite-derived, and high temporal and spatial resolution rain-gauge interpolated daily rainfall datasets. In order to prove that our results are also relevant for other climatic variables like pressure and temperature, we use re-analysis data provided by the National Center for Environmental Prediction and National Center for Atmospheric Research (NCEP/NCAR). We find that two of the patterns revealed from the CN extreme rainfall analysis coincide with those obtained for the pressure and temperature fields, and all four above mentioned patterns can be explained by topography, winds, and monsoon circulation. CN and ES enable to select the most informative regions for the ISM, providing realistic description of the ISM dynamics with fewer data, and also help to infer geographic pattern that are spatial signatures of the ISM. These patterns deserve a special attention for the meteorologists and can be used as markers of the ISM variability.

Global effects on Ionospheric Weather over the Indian subcontinent at Sunrise and Sunset

NASA Astrophysics Data System (ADS)

Basak, Tamal; Chakrabarti, S. K.; Pal, S.

2010-10-01

Study of Very Low Frequency (VLF) electromagnetic wave is very important for knowing the behavior of the Ionospheric layers due to Sunrise-Sunset, Earthquakes, Solar flares, Solar eclipses and other terrestrial and extra terrestrial radiations. We study the properties of the variation of the VLF signal strength theoretically all over Indian sub-continent. As an example, we concentrate on the VLF signal transmitted by Indian Naval Transmitter VTX at Vijayanarayanam (Latitude 08°23', Longitude 77°45') near the southern tip of Indian subcontinent. As has been noticed, several receiving stations placed during the VLF campaign in all over India, the VLF signal strength varies significantly with place and time. To understand the diurnal and seasonal variation of the received signal, a complete knowledge of physics of intensity distribution of the VLF signal is essential. The spatial variation of VLF signal plays an important role in selecting future VLF stations. In the wave-hop theoretical model presented here, horizontally stratified ionospheric layers have been considered. The VLF wave emitted by the transmitter has both the ground wave and the sky wave components. The ground wave attenuates during propagation. The sky wave component experiences reflections by the ionosphere on its way to the receiver and its attenuation depends on the degree of ionization. Intensity variation occurs at a given receiver location for interference among singly and multiply reflected waves. This has been simulated considering some simplified and justifiable assumptions. This spatial variation wave-hop theoretical model developed here has been compared with LWPC code generated results.

Global effects on Ionospheric Weather over the Indian subcontinent at Sunrise and Sunset

DOE Office of Scientific and Technical Information (OSTI.GOV)

Basak, Tamal; Pal, S.; Chakrabarti, S. K.

2010-10-20

Study of Very Low Frequency (VLF) electromagnetic wave is very important for knowing the behavior of the Ionospheric layers due to Sunrise-Sunset, Earthquakes, Solar flares, Solar eclipses and other terrestrial and extra terrestrial radiations. We study the properties of the variation of the VLF signal strength theoretically all over Indian sub-continent. As an example, we concentrate on the VLF signal transmitted by Indian Naval Transmitter VTX at Vijayanarayanam (Latitude 08 deg. 23', Longitude 77 deg. 45') near the southern tip of Indian subcontinent. As has been noticed, several receiving stations placed during the VLF campaign in all over India, themore » VLF signal strength varies significantly with place and time. To understand the diurnal and seasonal variation of the received signal, a complete knowledge of physics of intensity distribution of the VLF signal is essential. The spatial variation of VLF signal plays an important role in selecting future VLF stations. In the wave-hop theoretical model presented here, horizontally stratified ionospheric layers have been considered. The VLF wave emitted by the transmitter has both the ground wave and the sky wave components. The ground wave attenuates during propagation. The sky wave component experiences reflections by the ionosphere on its way to the receiver and its attenuation depends on the degree of ionization. Intensity variation occurs at a given receiver location for interference among singly and multiply reflected waves. This has been simulated considering some simplified and justifiable assumptions. This spatial variation wave-hop theoretical model developed here has been compared with LWPC code generated results.« less

Efficacy, Safety and Cost of Insecticide Treated Wall Lining, Insecticide Treated Bed Nets and Indoor Wall Wash with Lime for Visceral Leishmaniasis Vector Control in the Indian Sub-continent: A Multi-country Cluster Randomized Controlled Trial

PubMed Central

Das, Pradeep; Ghosh, Debashis; Priyanka, Jyoti; Matlashewski, Greg; Kroeger, Axel; Upfill-Brown, Alexander

2016-01-01

Background We investigated the efficacy, safety and cost of lime wash of household walls plus treatment of sand fly breeding places with bleach (i.e. environmental management or EM), insecticide impregnated durable wall lining (DWL), and bed net impregnation with slow release insecticide (ITN) for sand fly control in the Indian sub-continent. Methods This multi-country cluster randomized controlled trial had 24 clusters in each three sites with eight clusters per high, medium or low sand fly density stratum. Every cluster included 45–50 households. Five households from each cluster were randomly selected for entomological measurements including sand fly density and mortality at one, three, nine and twelve months post intervention. Household interviews were conducted for socioeconomic information and intervention acceptability assessment. Cost for each intervention was calculated. There was a control group without intervention. Findings Sand fly mortality [mean and 95%CI] ranged from 84% (81%-87%) at one month to 74% (71%-78%) at 12 months for DWL, 75% (71%-79%) at one month to 49% (43%-55%) at twelve months for ITN, and 44% (34%-53%) at one month to 22% (14%-29%) at twelve months for EM. Adjusted intervention effect on sand fly density measured by incidence rate ratio ranged from 0.28 (0.23–0.34) at one month to 0.62 (0.51–0.75) at 12 months for DWL; 0.72 (0.62–0.85) at one month to 1.02 (0.86–1.22) at 12 months for ITN; and 0.89 (0.76–1.03) at one months to 1.49 (1.26–1.74) at 12 months for EM. Household acceptance of EM was 74% compared to 94% for both DWL and ITN. Operational cost per household in USD was about 5, 8, and 2 for EM, DWL and ITN, respectively. Minimal adverse reactions were reported for EM and ITN while 36% of households with DWL reported transient itching. Interpretation DWL is the most effective, durable and acceptable control method followed by ITN. The Visceral Leishmaniasis (VL) Elimination Program in the Indian sub-continent

Permian biogeography of the Indian subcontinent with special reference to the marine fauna

NASA Astrophysics Data System (ADS)

Singh, Trilochan

Permian biogeography of the Indian subcontinent is discussed in the light of brachiopods and associated fossils from different localities. The discussion is based primarily on the Permian "biome" concept of Waterhouse and Bonham-Carter (1975), wherein three biomes are proposed: group A of subpolar, group B of temperate, and group C of tropical character. Data on the occurrence of Permian brachiopods and associated fossils are given for the Salt Range, Karakoram, and Himalayan regions of India, Nepal, Bhutan, Tibet, and Peninsular India with respect to the age of the fauna. Marine Permian localities of the Himalayan region include those of Ladakh, Zanskar, Lahaul and Spiti, Kashmir, Bhadarwah-Bhallesh-Chamba, Kinnaur, Garhwal, Kumaun, Darjeeling, Sikkim, and Arunachal Pradesh. Permian marine localities of Peninsular India, which forms a part of central Gondwanaland, include those of Bap, Badhaura, Umaria, Manendragarh, and Daltonganj, where marine transgression occurred in Early Permian time. The faunas of these localities are discussed with respect to their age, which falls into two groups, Early and Late Permian. It is suggested that widespread colder climatic conditions prevailed in the Indian subcontinent during the early Early Permian. Similar conditions continued in most of the localities until the late Early Permian, except at west Karakoram (Shaksgam valley), Zanskar, north Tibet (central and western part), and the Salt Range. However, during the Late Permian, climatic conditions were varied. Cold climatic conditions prevailed in north Tibet (central part), Kumaun Tethyan Himalaya, and south Tibet; temperate conditions occurred in west Karakoram (Shaksgam valley), Zanskar, Lahaul and Spiti, Bhadarwah-Bhallesh-Chamba, north Nepal, and north Sikkim; and tropical conditions occurred in the Salt Range, east Karakoram, Ladakh, Kashmir, and north Tibet (western and eastern parts). At a few localities there appear to be some anomalies that might be due to lack of

Globalization and Multilingualism: Case Studies of Indigenous Culture-Based Education from the Indian Sub-Continent and Their Implications

ERIC Educational Resources Information Center

Singh, Navin Kumar

2013-01-01

This paper presents some of the major program initiatives honoring Indigenous knowledge, culture, heritage, arts, and skills through curricular reforms and culturally appropriate educational practices on the Indian sub-continent. It presents case studies of Indigenous culture-based education, with reference to mother tongue and multicultural…

Tracing the geographic origin of traded leopard body parts in the indian subcontinent with DNA-based assignment tests.

PubMed

Mondol, Samrat; Sridhar, Vanjulavalli; Yadav, Prasanjeet; Gubbi, Sanjay; Ramakrishnan, Uma

2015-04-01

Illicit trade in wildlife products is rapidly decimating many species across the globe. Such trade is often underestimated for wide-ranging species until it is too late for the survival of their remaining populations. Policing this trade could be vastly improved if one could reliably determine geographic origins of illegal wildlife products and identify areas where greater enforcement is needed. Using DNA-based assignment tests (i.e., samples are assigned to geographic locations), we addressed these factors for leopards (Panthera pardus) on the Indian subcontinent. We created geography-specific allele frequencies from a genetic reference database of 173 leopards across India to infer geographic origins of DNA samples from 40 seized leopard skins. Sensitivity analyses of samples of known geographic origins and assignments of seized skins demonstrated robust assignments for Indian leopards. We found that confiscated pelts seized in small numbers were not necessarily from local leopards. The geographic footprint of large seizures appeared to be bigger than the cumulative footprint of several smaller seizures, indicating widespread leopard poaching across the subcontinent. Our seized samples had male-biased sex ratios, especially the large seizures. From multiple seized sample assignments, we identified central India as a poaching hotspot for leopards. The techniques we applied can be used to identify origins of seized illegal wildlife products and trade routes at the subcontinent scale and beyond. © 2014 Society for Conservation Biology.

Pseudovitamin D deficiency rickets—a report from the Indian subcontinent

PubMed Central

Zargar, A. H.; Mithal, A.; Wani, A. I.; Laway, B. A.; Masoodi, S. R.; Bashir, M. I.; Ganie, M. A.

2000-01-01

Pseudovitamin D deficiency rickets (also called vitamin D dependent rickets type I) is one of the types of inherited rickets and is caused by a deficit in renal 25-hydroxyvitamin D 1α-hydroxylase. This form of rickets has not been reported from the Indian subcontinent. Three patients with this disorder are presented. These patients were all females aged 3-20 years and presented with growth failure and skeletal deformities. All had florid clinical and radiological rickets. The biochemical abnormalities seen included hypocalcaemia, hypophosphataemia, and hyperphosphatasia. All patients had grossly raised 25-hydroxyvitamin D concentrations and markedly low to undetectable concentrations of 1,25-dihydroxyvitamin D. A disturbing feature of this study was the late referral of the patients.


Keywords: 1α-hydroxylase; calcitriol; inherited rickets; vitamin D dependent rickets PMID:10824056

Predicting potential distribution of poorly known species with small database: the case of four-horned antelope Tetracerus quadricornis on the Indian subcontinent.

PubMed

Pokharel, Krishna Prasad; Ludwig, Tobias; Storch, Ilse

2016-04-01

Information gaps on the distribution of data deficient and rare species such as four-horned antelope (FHA) in Nepal may impair their conservation. We aimed to empirically predict the distribution of FHA in Nepal with the help of data from the Indian subcontinent. Additionally, we wanted to identify core areas and gaps within the reported range limits and to assess the degree of isolation of known Nepalese populations from the main distribution areas in India. The tropical part of the Indian subcontinent (65°-90° eastern longitude, 5°-30° northern latitude), that is, the areas south of the Himalayan Mountains. Using MaxEnt and accounting for sampling bias, we developed predictive distribution models from environmental and topographical variables, and known presence locations of the study species in India and Nepal. We address and discuss the use of target group vs. random background. The prediction map reveals a disjunct distribution of FHA with core areas in the tropical parts of central to southern-western India. At the scale of the Indian subcontinent, suitable FHA habitat area in Nepal was small. The Indo-Gangetic Plain isolates Nepalese from the Indian FHA populations, but the distribution area extends further south than proposed by the current IUCN map. A low to intermediate temperature seasonality as well as low precipitation during the dry and warm season contributed most to the prediction of FHA distribution. The predicted distribution maps confirm other FHA range maps but also indicate that suitable areas exist south of the known range. Results further highlight that small populations in the Nepalese Terai Arc are isolated from the Indian core distribution and therefore might be under high extinction risk.

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent.

PubMed

Imamura, Hideo; Downing, Tim; Van den Broeck, Frederik; Sanders, Mandy J; Rijal, Suman; Sundar, Shyam; Mannaert, An; Vanaerschot, Manu; Berg, Maya; De Muylder, Géraldine; Dumetz, Franck; Cuypers, Bart; Maes, Ilse; Domagalska, Malgorzata; Decuypere, Saskia; Rai, Keshav; Uranw, Surendra; Bhattarai, Narayan Raj; Khanal, Basudha; Prajapati, Vijay Kumar; Sharma, Smriti; Stark, Olivia; Schönian, Gabriele; De Koning, Harry P; Settimo, Luca; Vanhollebeke, Benoit; Roy, Syamal; Ostyn, Bart; Boelaert, Marleen; Maes, Louis; Berriman, Matthew; Dujardin, Jean-Claude; Cotton, James A

2016-03-22

Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector-borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to 80% of global VL and over 30,000 deaths per year. Resistance against antimonial drugs has probably been a contributing factor in the persistence of this epidemic. Here we use whole genome sequences from 204 clinical isolates to track the evolution and epidemiology of L. donovani from the ISC. We identify independent radiations that have emerged since a bottleneck coincident with 1960s DDT spraying campaigns. A genetically distinct population frequently resistant to antimonials has a two base-pair insertion in the aquaglyceroporin gene LdAQP1 that prevents the transport of trivalent antimonials. We find evidence of genetic exchange between ISC populations, and show that the mutation in LdAQP1 has spread by recombination. Our results reveal the complexity of L. donovani evolution in the ISC in response to drug treatment.

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

PubMed Central

Imamura, Hideo; Downing, Tim; Van den Broeck, Frederik; Sanders, Mandy J; Rijal, Suman; Sundar, Shyam; Mannaert, An; Vanaerschot, Manu; Berg, Maya; De Muylder, Géraldine; Dumetz, Franck; Cuypers, Bart; Maes, Ilse; Domagalska, Malgorzata; Decuypere, Saskia; Rai, Keshav; Uranw, Surendra; Bhattarai, Narayan Raj; Khanal, Basudha; Prajapati, Vijay Kumar; Sharma, Smriti; Stark, Olivia; Schönian, Gabriele; De Koning, Harry P; Settimo, Luca; Vanhollebeke, Benoit; Roy, Syamal; Ostyn, Bart; Boelaert, Marleen; Maes, Louis; Berriman, Matthew; Dujardin, Jean-Claude; Cotton, James A

2016-01-01

Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector-borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to 80% of global VL and over 30,000 deaths per year. Resistance against antimonial drugs has probably been a contributing factor in the persistence of this epidemic. Here we use whole genome sequences from 204 clinical isolates to track the evolution and epidemiology of L. donovani from the ISC. We identify independent radiations that have emerged since a bottleneck coincident with 1960s DDT spraying campaigns. A genetically distinct population frequently resistant to antimonials has a two base-pair insertion in the aquaglyceroporin gene LdAQP1 that prevents the transport of trivalent antimonials. We find evidence of genetic exchange between ISC populations, and show that the mutation in LdAQP1 has spread by recombination. Our results reveal the complexity of L. donovani evolution in the ISC in response to drug treatment. DOI: http://dx.doi.org/10.7554/eLife.12613.001 PMID:27003289

Comparison of Indian subcontinent and Middle East acute heart failure patients: Results from the Gulf Acute Heart Failure Registry

PubMed Central

Panduranga, Prashanth; Al-Zakwani, Ibrahim; Sulaiman, Kadhim; Al-Habib, Khalid; Alsheikh-Ali, Alawi; Al-Suwaidi, Jassim; Al-Mahmeed, Wael; Al-Faleh, Hussam; Elasfar, Abdelfatah; Ridha, Mustafa; Bulbanat, Bassam; Al-Jarallah, Mohammed; Asaad, Nidal; Bazargani, Nooshin; Al-Motarreb, Ahmed; Amin, Haitham

2016-01-01

Objective To compare Middle East Arabs and Indian subcontinent acute heart failure (AHF) patients. Methods AHF patients admitted from February 14, 2012 to November 14, 2012 in 47 hospitals among 7 Middle East countries. Results The Middle Eastern Arab group (4157) was older (60 vs. 54 years), with high prevalence of coronary artery disease (48% vs. 37%), valvular heart disease (14% vs. 7%), atrial fibrillation (12% vs. 7%), and khat chewing (21% vs. 1%). Indian subcontinent patients (382) were more likely to be smokers (36% vs. 21%), alcohol consumers (11% vs. 2%), diabetic (56% vs. 49%) with high prevalence of AHF with reduced ejection fraction (76% vs. 65%), and with acute coronary syndrome (46% vs. 26%). In-hospital mortality was 6.5% with no difference, but 3-month and 12-month mortalities were significantly high among Middle East Arabs, (13.7% vs. 7.6%) and (22.8% vs. 17.1%), respectively. Conclusions AHF patients from this region are a decade younger than Western patients with high prevalence of ischemic heart disease, diabetes mellitus, and AHF with reduced ejection fraction. There is an urgent need to control risk factors among both groups, as well as the need for setting up heart failure clinics for better postdischarge management. PMID:27056651

Natural disaster-induced environmental migration from the Indian subcontinent resulting in malaria outbreak in Greece

NASA Astrophysics Data System (ADS)

Mavrouli, Maria; Mavroulis, Spyridon; Piperaki, Evangelia-Theofano; Hadjichristodoulou, Christos; Tsakris, Athanassios

2017-04-01

Extreme hydrometeorological disasters such as floods and hurricanes can severely damage human life, natural and built environment and economic development. Consequently, they can result in environmental migration (EM). In case of infectious disease (ID) outbreaks during the post-disaster period and subsequent EM, environmental refugees from endemic regions serve as ID carriers to their new residence sites altering the spatial ID distribution and incidence. The continuous massive influx of environmental refugees from malaria endemic regions to non-endemic ones can build up a parasite reservoir among naive host populations. Initially, serum specimens were collected in 2012 from asymptomatic individuals, 298 Greeks and 721 immigrants residing in areas of documented local malaria transmission in Laconia (Southern Peloponnese) and in Eastern Attica, Greece. Sera were tested for antibodies against Plasmodium vivax and P. falciparum using the Malaria-Ab ELISA (IBL International GMBH, Hamburg, Germany). Taking into account that Greece has been declared malaria free by the WHO since 1974, we conducted an extensive and systematic literature review related to natural disasters leading among others to increased malaria risk in Indian Subcontinent and respective forced EM in order to detect relative possible causes of reintroduction and localized outbreaks of malaria in Greece. Regarding the country of origin, information was available for 685 (95%) of the 721 immigrants. Of the 678 immigrants from Indian Subcontinent, 627 (92.5%) originated from Pakistan, 24 (3.53%) Afghanistan, 24 (3.53%) India and 3 (0.44%) Bangladesh. Of the 721 immigrants, 582 and 124 resided in Laconia and Eastern Attica respectively. Seventy-one immigrants residing in Laconia and 14 in Eastern Attica were positive for antimalarial antibodies, while none of the 298 Greeks residing in Laconia (N=248) and Attica (N=50) was found positive. Based on already published scientific data, Pakistan has been exposed

Cereal based functional food of Indian subcontinent: a review.

PubMed

Das, Arpita; Raychaudhuri, Utpal; Chakraborty, Runu

2012-12-01

Due to constant health awareness and readily available information on usefulness of different diet and their direct link with health, the demand of functional food is increasing day by day. The concept of functional foods includes foods or food ingredients that exert a beneficial effect on host health and/or reduce the risk of chronic disease beyond basic nutritional functions. Increasing awareness of consumer health and interest in functional foods to achieve a healthy lifestyle has resulted in the need for food products with versatile health-benefiting properties. Cereal- and cereal component-based food products offer opportunities to include probiotics, prebiotics, and fibers in the human diet. Various growth studies using probiotic Lactic acid bacteria on cereal-based substrates and utilization of whole grain or components as high-fiber foods in developing novel food products lend support to the idea that cereal-based media may well be good probiotic carriers. It is essential that science and traditional knowledge should go together to find mutually beneficial results. In the Indian subcontinent, making use of fermented food and beverages using local food crops and other biological resources are very common. But the nature of the products and the base material vary from region to region.

Towards elimination of visceral leishmaniasis in the Indian subcontinent-Translating research to practice to public health.

PubMed

Hirve, Siddhivinayak; Kroeger, Axel; Matlashewski, Greg; Mondal, Dinesh; Banjara, Megha Raj; Das, Pradeep; Be-Nazir, Ahmed; Arana, Byron; Olliaro, Piero

2017-10-01

The decade following the Regional Strategic Framework for Visceral Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of VL burden in the Indian subcontinent. The Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the World Health Organization (WHO) and other stakeholders, has coordinated and financed research for the development of new innovative tools and strategies to support the regional VL elimination initiative. This paper describes the process of the TDR's engagement and contribution to this initiative. Multiple databases were searched to identify 152 scientific papers and reports with WHO funding or authorship affiliation around the following 3 framework strategies: detection of new cases, morbidity reduction, and prevention of infection. TDR has played a critical role in the evaluation and subsequent use of the 39-aminoacid-recombinant kinesin antigen (rK39) rapid diagnostic test (RDT) as a confirmatory test for VL in the national program. TDR has supported the clinical research and development of miltefosine and single-dose liposomal amphotericin B as a first-line treatment against VL. TDR has engaged with in-country researchers, national programme managers, and partners to generate evidence-based interventions for early detection and treatment of VL patients. TDR evaluated the quality, community acceptance, and cost effectiveness of indoor residual spraying, insecticide-treated bed nets, insecticide-impregnated durable wall linings, insecticidal paint, and environmental management as tools for integrated vector management in reducing sandfly density. TDR's engagement with country policy makers, scientists, and clinicians in the development of effective diagnosis, treatment, case detection, and vector control represents an important example of TDR's stewardship toward the elimination of VL in the Indian subcontinent.

Literature of the Indian Subcontinent.

ERIC Educational Resources Information Center

Dimock, Edward C., Jr.

Indian literature is intimately bound up with the Indian religious system. The earliest sacred writings are the Vedas. In addition to being poetry on nature, and later on, ritual formulae for controlling the universe, the Vedas have philosophical speculation. A large part of classical Indian literature consists of writing commentaries on…

First report of Perkinsus beihaiensis in Crassostrea madrasensis from the Indian subcontinent.

PubMed

Sanil, N K; Suja, G; Lijo, J; Vijayan, K K

2012-04-26

Protozoan parasites of the genus Perkinsus are considered important pathogens responsible for mass mortalities in many wild and farmed bivalve populations. The present study was initiated to screen populations of the Indian edible oyster Crassostrea madrasensis, a promising candidate for aquaculture along the Indian coasts, for the presence of Perkinsus spp. The study reports the presence of P. beihaiensis for the first time in C. madrasensis populations from the Indian subcontinent and south Asia. Samples collected from the east and west coasts of India were subjected to Ray's fluid thioglycollate medium (RFTM) culture and histology which indicated the presence of Perkinsus spp. PCR screening of the tissues using specific primers amplified the product specific to the genus Perkinsus. The taxonomic affinities of the parasites were determined by sequencing both internal transcribed spacer (ITS) and actin genes followed by basic local alignment search tool (BLAST) analysis. Analysis based on the ITS sequences showed 98 to 100% identity to Perkinsus spp. (P. beihaiensis and Brazilian Perkinsus sp.). The pairwise genetic distance values and phylogenetic analysis confirmed that 2 of the present samples belonged to the P. beihaiensis clade while the other 4 showed close affinities with the Brazilian Perkinsus sp. clade. The genetic divergence data, close affinity with the Brazilian Perkinsus sp., and co-existence with P. beihaiensis in the same host species in the same habitat show that the remaining 4 samples exhibit some degree of variation from P. beihaiensis. As expected, the sequencing of actin genes did not show any divergence among the samples studied. They probably could be intraspecific variants of P. beihaiensis having a separate lineage in the process of evolution.

Seasonal variability of aerosol optical depth over Indian subcontinent

USGS Publications Warehouse

Prasad, A.K.; Singh, R.P.; Singh, A.; Kafatos, M.

2005-01-01

Ganga basin extends 2000 km E-W and about 400 km N-S and is bounded by Himalayas in the north. This basin is unequivocally found to be affected by high aerosols optical depth (AOD) (>0.6) throughout the year. Himalayas restricts movement of aerosols toward north and as a result dynamic nature of aerosol is seen over the Ganga basin. High AOD in this region has detrimental effects on health of more than 460 million people living in this part of India besides adversely affecting clouds formation, monsoonal rainfall pattern and Normalized Difference Vegetation Index (NDVI). Severe drought events (year 2002) in Ganga basin and unexpected failure of monsoon several times, occurred in different parts of Indian subcontinent. Significant rise in AOD (18.7%) over the central part of basin (Kanpur region) have been found to cause substantial decrease in NDVI (8.1%) since 2000. A negative relationship is observed between AOD and NDVI, magnitude of which differs from region to region. Efforts have been made to determine general distribution of AOD and its dominant departure in recent years spatially using Moderate Resolution Imaging Spectroradiometer (MODIS) data. The seasonal changes in aerosol optical depth over the Indo-Gangetic basin is found to very significant as a result of the increasing dust storm events in recent years. ?? 2005 IEEE.

Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent

PubMed Central

Imamura, H.; Zander, D.; D’Haenens, E.; Maes, I.; Domagalska, M. A.; Clos, J.

2018-01-01

ABSTRACT Antimonials (Sb) were used for decades for chemotherapy of visceral leishmaniasis (VL). Now abandoned in the Indian subcontinent (ISC) because of Leishmania donovani resistance, this drug offers a unique model for understanding drug resistance dynamics. In a previous phylogenomic study, we found two distinct populations of L. donovani: the core group (CG) in the Gangetic plains and ISC1 in the Nepalese highlands. Sb resistance was only encountered within the CG, and a series of potential markers were identified. Here, we analyzed the development of resistance to trivalent antimonials (SbIII) upon experimental selection in ISC1 and CG strains. We observed that (i) baseline SbIII susceptibility of parasites was higher in ISC1 than in the CG, (ii) time to SbIII resistance was higher for ISC1 parasites than for CG strains, and (iii) untargeted genomic and metabolomic analyses revealed molecular changes along the selection process: these were more numerous in ISC1 than in the CG. Altogether these observations led to the hypothesis that CG parasites are preadapted to SbIII resistance. This hypothesis was experimentally confirmed by showing that only wild-type CG strains could survive a direct exposure to the maximal concentration of SbIII. The main driver of this preadaptation was shown to be MRPA, a gene involved in SbIII sequestration and amplified in an intrachromosomal amplicon in all CG strains characterized so far. This amplicon emerged around 1850 in the CG, well before the implementation of antimonials for VL chemotherapy, and we discuss here several hypotheses of selective pressure that could have accompanied its emergence. IMPORTANCE The “antibiotic resistance crisis” is a major challenge for scientists and medical professionals. This steady rise in drug-resistant pathogens also extends to parasitic diseases, with antimony being the first anti-Leishmania drug that fell in the Indian subcontinent (ISC). Leishmaniasis is a major but neglected

Ethnobotanical uses of neem (Azadirachta indica A.Juss.; Meliaceae) leaves in Bali (Indonesia) and the Indian subcontinent in relation with historical background and phytochemical properties.

PubMed

Sujarwo, Wawan; Keim, Ary P; Caneva, Giulia; Toniolo, Chiara; Nicoletti, Marcello

2016-08-02

Neem (Azadirachta indica; Meliaceae) is widely known for its cold pressed seed oil, mainly used as insecticide, but also for cosmetic, medicinal and agricultural uses. The seed oil is widely employed in the Indian subcontinent, and the leaves seem to have a lower relevance, but the ethnobotanical information of Bali (Indonesia) considers the utilisation of leaves for medicinal properties. We report ethnopharmacological information about current uses of neem, in particular of the leaves, besides the insecticidal one, we discuss on the historical background of their uses. Ethnobotanical data were collected using both literature and scientific references and semi-structured interviews with 50 informants (ages ranged between 14 and 76 years old) through the snowball method in thirteen aga (indigenous Balinese) villages, following Ethic code procedures. The informants were asked to specify: which part of the plant was used, and how that plant part was used. Plant specimens were collected, identified and made into herbarium voucher. In consideration of the high variability and complex chemical constituent of neem, a HPTLC analysis of neem leaves coming from both the Indonesian island of Bali and the Indian subcontinent was carried out. The data on the medical use of traditional preparations from leaves of neem display a wide spectrum of applications. In the Indian subcontinent, neem leaves are used to treat dental and gastrointestinal disorders, malaria fevers, skin diseases, and as insects repellent, while the Balinese used neem leaves as a diuretic and for diabetes, headache, heartburn, and stimulating the appetite. Differences in utilisation cannot be related to chemical differences and other constituents besides limonoids must be investigated and related to the multipurpose activity of neem. This study revealed that neem leaves are believed to treat diabetes in both Balinese and Indian communities. Limonoids can not be considered the only responsible of digestive

A dipole pattern of summertime rainfall across the Indian subcontinent and the Tibetan Plateau

NASA Astrophysics Data System (ADS)

Jiang, X.; Ting, M.

2017-12-01

The Tibetan Plateau (TP) has long been regarded as a key driver for the formation and variations of the Indian summer monsoon (ISM). Recent studies, however, indicated that the ISM also exerts a considerable impact on rainfall variations in the TP, suggesting that the ISM and the TP should be considered as an interactive system. From this perspective, we investigate the co-variability of the July-August mean rainfall across the Indian subcontinent (IS) and the TP. We found that the interannual variation of IS and TP rainfall exhibits a dipole pattern in which rainfall in the central and northern IS tends to be out of phase with that in the southeastern TP. This dipole pattern is associated with significant anomalies in rainfall, atmospheric circulation, and water vapor transport over the Asian continent and nearby oceans. Rainfall anomalies and the associated latent heating in the central and northern IS tend to induce changes in regional circulation -that suppress rainfall in the southeastern TP and vice versa. Furthermore, the sea surface temperature anomalies in the tropical southeastern Indian Ocean can trigger the dipole rainfall pattern by suppressing convection over the central IS and the northern Bay of Bengal, which further induces anomalous anticyclonic circulation to the south of TP that favors more rainfall in the southeastern TP by transporting more water vapor to the region. The dipole pattern is also linked to the Silk-Road wave train due to its link to rainfall over the northwestern IS.

Population Stratification and Underrepresentation of Indian Subcontinent Genetic Diversity in the 1000 Genomes Project Dataset

PubMed Central

Sengupta, Dhriti; Choudhury, Ananyo; Basu, Analabha; Ramsay, Michèle

2016-01-01

Genomic variation in Indian populations is of great interest due to the diversity of ancestral components, social stratification, endogamy and complex admixture patterns. With an expanding population of 1.2 billion, India is also a treasure trove to catalogue innocuous as well as clinically relevant rare mutations. Recent studies have revealed four dominant ancestries in populations from mainland India: Ancestral North-Indian (ANI), Ancestral South-Indian (ASI), Ancestral Tibeto–Burman (ATB) and Ancestral Austro-Asiatic (AAA). The 1000 Genomes Project (KGP) Phase-3 data include about 500 genomes from five linguistically defined Indian-Subcontinent (IS) populations (Punjabi, Gujrati, Bengali, Telugu and Tamil) some of whom are recent migrants to USA or UK. Comparative analyses show that despite the distinct geographic origins of the KGP-IS populations, the ANI component is predominantly represented in this dataset. Previous studies demonstrated population substructure in the HapMap Gujrati population, and we found evidence for additional substructure in the Punjabi and Telugu populations. These substructured populations have characteristic/significant differences in heterozygosity and inbreeding coefficients. Moreover, we demonstrate that the substructure is better explained by factors like differences in proportion of ancestral components, and endogamy driven social structure rather than invoking a novel ancestral component to explain it. Therefore, using language and/or geography as a proxy for an ethnic unit is inadequate for many of the IS populations. This highlights the necessity for more nuanced sampling strategies or corrective statistical approaches, particularly for biomedical and population genetics research in India. PMID:27797945

Planetary boundary layer height over the Indian subcontinent: Variability and controls with respect to monsoon

NASA Astrophysics Data System (ADS)

Sathyanadh, Anusha; Prabhakaran, Thara; Patil, Chetana; Karipot, Anandakumar

2017-10-01

Planetary boundary layer (PBL) height characteristics over the Indian sub-continent at diurnal to seasonal scales and its controlling factors in relation to monsoon are investigated. The reanalysis (Modern Era Retrospective analysis for Research and Applications, MERRA) PBL heights (PBLH) used for the study are validated against those derived from radiosonde observations and radio occultation air temperature and humidity profiles. The radiosonde observations include routine India Meteorological Department observations at two locations (coastal and an inland) for one full year and campaign based early afternoon radiosonde observations at six inland locations over the study region for selected days from May-September 2011. The temperature and humidity profiles from radio occultations spread over the sub-continent at irregular timings during the year 2011. The correlations and root mean square errors are in the range 0.74-0.83 and 407 m-643 m, respectively. Large pre-monsoon, monsoon and post-monsoon variations in PBL maximum height (1000 m-4000 m), time of occurrence of maximum height (11:00 LST-17:00 LST) and growth rate (100 to 400 m h- 1) are noted over the land, depending on geographical location and more significantly on the moisture availability which influences the surface sensible and latent heat fluxes. The PBLH variations associated with active-break intra-seasonal monsoon oscillations are up to 1000 m over central Indian locations. Inter relationship between the PBLH and the controlling factors, i.e. Evaporative Fraction, net radiation, friction velocity, surface Richardson number, and scalar diffusivity fraction, show significant variation between dry and wet PBL regimes, which also varies with geographical location. Evaporative fraction has dominant influence on the PBLH over the region. Enhanced entrainment during monsoon contributes to reduction in PBLH, whereas the opposite effect is noted during dry period. Linear regression, cross wavelet and

Continuity of mammalian fauna over the last 200,000 y in the Indian subcontinent

PubMed Central

Roberts, Patrick; Delson, Eric; Miracle, Preston; Ditchfield, Peter; Roberts, Richard G.; Jacobs, Zenobia; Blinkhorn, James; Ciochon, Russell L.; Fleagle, John G.; Frost, Stephen R.; Gilbert, Christopher C.; Gunnell, Gregg F.; Harrison, Terry; Korisettar, Ravi; Petraglia, Michael D.

2014-01-01

Mammalian extinction worldwide during the Late Pleistocene has been a major focus for Quaternary biochronology and paleoecology. These extinctions have been variably attributed to the impacts of climate change and human interference. However, until relatively recently, research has been largely restricted to the Americas, Europe, and Australasia. We present the oldest Middle–Late Pleistocene stratified and numerically dated faunal succession for the Indian subcontinent from the Billasurgam cave complex. Our data demonstrate continuity of 20 of 21 identified mammalian taxa from at least 100,000 y ago to the present, and in some cases up to 200,000 y ago. Comparison of this fossil record to contemporary faunal ranges indicates some geographical redistribution of mammalian taxa within India. We suggest that, although local extirpations occurred, the majority of taxa survived or adapted to substantial ecological pressures in fragmented habitats. Comparison of the Indian record with faunal records from Southeast and Southwest Asia demonstrates the importance of interconnected mosaic habitats to long-term faunal persistence across the Asian tropics. The data presented here have implications for mammalian conservation in India today, where increasing ecological circumscription may leave certain taxa increasingly endangered in the most densely populated region of the world. PMID:24711426

Visceral Leishmaniasis on the Indian Subcontinent: Modelling the Dynamic Relationship between Vector Control Schemes and Vector Life Cycles.

PubMed

Poché, David M; Grant, William E; Wang, Hsiao-Hsuan

2016-08-01

Visceral leishmaniasis (VL) is a disease caused by two known vector-borne parasite species (Leishmania donovani, L. infantum), transmitted to man by phlebotomine sand flies (species: Phlebotomus and Lutzomyia), resulting in ≈50,000 human fatalities annually, ≈67% occurring on the Indian subcontinent. Indoor residual spraying is the current method of sand fly control in India, but alternative means of vector control, such as the treatment of livestock with systemic insecticide-based drugs, are being evaluated. We describe an individual-based, stochastic, life-stage-structured model that represents a sand fly vector population within a village in India and simulates the effects of vector control via fipronil-based drugs orally administered to cattle, which target both blood-feeding adults and larvae that feed on host feces. Simulation results indicated efficacy of fipronil-based control schemes in reducing sand fly abundance depended on timing of drug applications relative to seasonality of the sand fly life cycle. Taking into account cost-effectiveness and logistical feasibility, two of the most efficacious treatment schemes reduced population peaks occurring from April through August by ≈90% (applications 3 times per year at 2-month intervals initiated in March) and >95% (applications 6 times per year at 2-month intervals initiated in January) relative to no control, with the cumulative number of sand fly days occurring April-August reduced by ≈83% and ≈97%, respectively, and more specifically during the summer months of peak human exposure (June-August) by ≈85% and ≈97%, respectively. Our model should prove useful in a priori evaluation of the efficacy of fipronil-based drugs in controlling leishmaniasis on the Indian subcontinent and beyond.

Population Stratification and Underrepresentation of Indian Subcontinent Genetic Diversity in the 1000 Genomes Project Dataset.

PubMed

Sengupta, Dhriti; Choudhury, Ananyo; Basu, Analabha; Ramsay, Michèle

2016-12-31

Genomic variation in Indian populations is of great interest due to the diversity of ancestral components, social stratification, endogamy and complex admixture patterns. With an expanding population of 1.2 billion, India is also a treasure trove to catalogue innocuous as well as clinically relevant rare mutations. Recent studies have revealed four dominant ancestries in populations from mainland India: Ancestral North-Indian (ANI), Ancestral South-Indian (ASI), Ancestral Tibeto-Burman (ATB) and Ancestral Austro-Asiatic (AAA). The 1000 Genomes Project (KGP) Phase-3 data include about 500 genomes from five linguistically defined Indian-Subcontinent (IS) populations (Punjabi, Gujrati, Bengali, Telugu and Tamil) some of whom are recent migrants to USA or UK. Comparative analyses show that despite the distinct geographic origins of the KGP-IS populations, the ANI component is predominantly represented in this dataset. Previous studies demonstrated population substructure in the HapMap Gujrati population, and we found evidence for additional substructure in the Punjabi and Telugu populations. These substructured populations have characteristic/significant differences in heterozygosity and inbreeding coefficients. Moreover, we demonstrate that the substructure is better explained by factors like differences in proportion of ancestral components, and endogamy driven social structure rather than invoking a novel ancestral component to explain it. Therefore, using language and/or geography as a proxy for an ethnic unit is inadequate for many of the IS populations. This highlights the necessity for more nuanced sampling strategies or corrective statistical approaches, particularly for biomedical and population genetics research in India. © The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Phylogeography of the Small Indian Civet and Origin of Introductions to Western Indian Ocean Islands.

PubMed

Gaubert, Philippe; Patel, Riddhi P; Veron, Géraldine; Goodman, Steven M; Willsch, Maraike; Vasconcelos, Raquel; Lourenço, André; Sigaud, Marie; Justy, Fabienne; Joshi, Bheem Dutt; Fickel, Jörns; Wilting, Andreas

2017-05-01

The biogeographic dynamics affecting the Indian subcontinent, East and Southeast Asia during the Plio-Pleistocene has generated complex biodiversity patterns. We assessed the molecular biogeography of the small Indian civet (Viverricula indica) through mitogenome and cytochrome b + control region sequencing of 89 historical and modern samples to (1) establish a time-calibrated phylogeography across the species' native range and (2) test introduction scenarios to western Indian Ocean islands. Bayesian phylogenetic analyses identified 3 geographic lineages (East Asia, sister-group to Southeast Asia and the Indian subcontinent + northern Indochina) diverging 3.2-2.3 million years ago (Mya), with no clear signature of past demographic expansion. Within Southeast Asia, Balinese populations separated from the rest 2.6-1.3 Mya. Western Indian Ocean populations were assigned to the Indian subcontinent + northern Indochina lineage and had the lowest mitochondrial diversity. Approximate Bayesian computation did not distinguish between single versus multiple introduction scenarios. The early diversification of the small Indian civet was likely shaped by humid periods in the Late Pliocene-Early Pleistocene that created evergreen rainforest barriers, generating areas of intra-specific endemism in the Indian subcontinent, East, and Southeast Asia. Later, Pleistocene dispersals through drier conditions in South and Southeast Asia were likely, giving rise to the species' current natural distribution. Our molecular data supported the delineation of only 4 subspecies in V. indica, including an endemic Balinese lineage. Our study also highlighted the influence of prefirst millennium AD introductions to western Indian Ocean islands, with Indian and/or Arab traders probably introducing the species for its civet oil. © The American Genetic Association 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Modeling of sub-ionospheric VLF signal perturbations associated with total solar eclipse, 2009 in Indian subcontinent

NASA Astrophysics Data System (ADS)

Pal, Sujay; Chakrabarti, Sandip K.; Mondal, Sushanta K.

2012-07-01

During the total solar eclipse of 2009, a week-long campaign was conducted in the Indian sub-continent to study the low-latitude D-region ionosphere using the very low frequency (VLF) signal from the Indian Navy transmitter (call sign: VTX3) operating at 18.2 kHz. It was observed that in several places, the signal amplitude is enhanced while in other places the amplitude is reduced. We simulated the observational results using the well known Long Wavelength Propagation Capability (LWPC) code. As a first order approximation, the ionospheric parameters were assumed to vary according to the degree of solar obscuration on the way to the receivers. This automatically brought in non-uniformity of the ionospheric parameters along the propagation paths. We find that an assumption of 4 km increase of lower ionospheric height for places going through totality in the propagation path simulate the observations very well at Kathmandu and Raiganj. We find an increase of the height parameter by h'=+3.0 km for the VTX-Malda path and h'=+1.8 km for the VTX-Kolkata path. We also present, as an example, the altitude variation of electron number density throughout the eclipse time at Raiganj.

Influence of water stress on the carbon isotopic composition of modern plants: Implications for C4 plant appearance in Indian subcontinent

NASA Astrophysics Data System (ADS)

Basu, S.; Ghosh, S.; Sanyal, P.

2016-12-01

The carbon isotopic composition (d13C) of modern terrestrial plants (C3 and C4) provides the baseline to understand past vegetation composition, paleodietary changes and animal migration etc. Accuracy of past environment reconstruction is dependent on the end-member d13C values of plants which found to vary in regional scale. For instance, the d13C values of Indian C3 plants (d13CC3) are 1 to 2‰ more negative compared to global mean. As observed, most of the previous database is devoid of samples from tropical monsoon realm (like India) and the difference between global and regional mean may introduce errors in vegetation reconstruction. To constrain end-member d13CC3 value, published and newly generated results from wide range of mean annual precipitation (MAP: 1-11,700 mm) are compiled which is ca. 1.5 higher in sample size (n=2440) compared to previous database. Using logarithmic function, new relationship between d13C value and MAP (d13CC3 (‰) =20.1585(0.3061)-1.1276(0.0489)ln(MAP+700)) is proposed. The modeled mean d13CC3 value (-28.9‰) is close to average d13CC3 value for Indian plants (-29.1‰) and suggests the importance of vegetation from low-latitudinal tropical region in global compilation. It was observed that C3 plants, on a global scale, are less sensitive to wet climate relative to dry condition. This inference is in agreement with the paleoclimatic data from Indian subcontinent for the late Quaternary period. Despite well established correlation between d13CC3 value and MAP, previous investigation from Indian subcontinent used fixed end-member values to reconstruct past vegetation and total change in the d13C value of proxies was attributed to changes in relative abundance of C3 and C4 plants. Using region-specific mean d13C value of plants, after correcting for changing MAP and error propagation, existence of C4 before ca. 11 Ma plant is observed; earlier to previous reported timing.

mtDNA from the Early Bronze Age to the Roman Period Suggests a Genetic Link between the Indian Subcontinent and Mesopotamian Cradle of Civilization

PubMed Central

Witas, Henryk W.; Tomczyk, Jacek; Jędrychowska-Dańska, Krystyna; Chaubey, Gyaneshwer; Płoszaj, Tomasz

2013-01-01

Ancient DNA methodology was applied to analyse sequences extracted from freshly unearthed remains (teeth) of 4 individuals deeply deposited in slightly alkaline soil of the Tell Ashara (ancient Terqa) and Tell Masaikh (ancient Kar-Assurnasirpal) Syrian archaeological sites, both in the middle Euphrates valley. Dated to the period between 2.5 Kyrs BC and 0.5 Kyrs AD the studied individuals carried mtDNA haplotypes corresponding to the M4b1, M49 and/or M61 haplogroups, which are believed to have arisen in the area of the Indian subcontinent during the Upper Paleolithic and are absent in people living today in Syria. However, they are present in people inhabiting today’s Tibet, Himalayas, India and Pakistan. We anticipate that the analysed remains from Mesopotamia belonged to people with genetic affinity to the Indian subcontinent since the distribution of identified ancient haplotypes indicates solid link with populations from the region of South Asia-Tibet (Trans-Himalaya). They may have been descendants of migrants from much earlier times, spreading the clades of the macrohaplogroup M throughout Eurasia and founding regional Mesopotamian groups like that of Terqa or just merchants moving along trade routes passing near or through the region. None of the successfully identified nuclear alleles turned out to be ΔF508 CFTR, LCT-13910T or Δ32 CCR5. PMID:24040024

Analysis of MAGSAT and surface data of the Indian region

NASA Technical Reports Server (NTRS)

Agarwal, G. C. (Principal Investigator)

1983-01-01

Techniques and significant results of an analysis of MAGSAT and surface data of the Indian region are described. Specific investigative tasks included: (1) use of the multilevel data at different altitudes to develop a model for variation of magnetic anomaly with altitude; (2) development of the regional model for the description of main geomagnetic field for the Indian sub-continent using MAGSAT and observatory data; (3) development of regional mathematical model of secular variations over the Indian sub-continent; and (4) downward continuation of the anomaly field obtained from MAGSAT and its combination with the existing observatory data to produce a regional anomaly map for elucidating tectonic features of the Indian sub-continent.

Decreasing Indian summer monsoon on the northern Indian sub-continent during the last 180 years: evidence from five tree-ring cellulose oxygen isotope chronologies

NASA Astrophysics Data System (ADS)

Xu, Chenxi; Sano, Masaki; Priyadarshan Dimri, Ashok; Ramesh, Rengaswamy; Nakatsuka, Takeshi; Shi, Feng; Guo, Zhengtang

2018-05-01

We have constructed a regional tree-ring cellulose oxygen isotope (δ18O) record for the northern Indian sub-continent based on two new records from northern India and central Nepal and three published records from northwestern India, western Nepal and Bhutan. The record spans the common interval from 1743 to 2008 CE. Correlation analysis reveals that the record is significantly and negatively correlated with the three regional climatic indices: all India rainfall (AIR; r = -0.5, p < 0.001, n = 138), Indian monsoon index (IMI; r = -0.45, p < 0.001, n = 51) and the intensity of monsoonal circulation (r = -0.42, p < 0.001, n = 51). The close relationship between tree-ring cellulose δ18O and the Indian summer monsoon (ISM) can be explained by oxygen isotope fractionation mechanisms. Our results indicate that the regional tree-ring cellulose δ18O record is suitable for reconstructing high-resolution changes in the ISM. The record exhibits significant interannual and long-term variations. Interannual changes are closely related to the El Niño-Southern Oscillation (ENSO), which indicates that the ISM was affected by ENSO in the past. However, the ISM-ENSO relationship was not consistent over time, and it may be partly modulated by Indian Ocean sea surface temperature (SST). Long-term changes in the regional tree-ring δ18O record indicate a possible trend of weakened ISM intensity since 1820. Decreasing ISM activity is also observed in various high-resolution ISM records from southwest China and Southeast Asia, and may be the result of reduced land-ocean thermal contrasts since 1820 CE.

What drives observed space-borne variations of formaldehyde columns over the Indian subcontinent?

NASA Astrophysics Data System (ADS)

Surl, Luke; Palmer, Paul

2017-04-01

Oxidation of volatile organic compounds (VOCs) leads to the formation of secondary air pollutants (e.g. formaldehyde, HCHO) and secondary organic aerosol linked with deleterious impacts on human health. Our focus in this study is the Indian subcontinent where there is a range of chemical environments that span forest ecosystems (dominated by biogenic VOCs) to megacities that are sometimes influenced by upwind sources (e.g. agricultural burning), both with and without some marine influence. To understand this range of environments we use space-borne column observations of HCHO from the Ozone Monitoring Instrument (OMI), in coordination with the GEOS-Chem atmospheric chemistry transport model, to provide insight into the emissions and photochemical processes in the atmosphere. As part of this work we have developed a HCHO vertical column product using slant column retrievals from the NASA OMHCHO v003 product combined with air-mass factors determined by a high-resolution (c25 km), nested run of the GEOS-Chem model. We report our analysis for a calendar year, studying in particular seasonal cycles associated with biogenic emissions, agricultural burning, and meteorology (most notably monsoon dynamics). We also consider the extent to which these satellite data can provide information on city-sized spatial scales, and investigate such an approach for some of India's megacities.

The assessment of Global Precipitation Measurement estimates over the Indian subcontinent

NASA Astrophysics Data System (ADS)

Murali Krishna, U. V.; Das, Subrata Kumar; Deshpande, Sachin M.; Doiphode, S. L.; Pandithurai, G.

2017-08-01

Accurate and real-time precipitation estimation is a challenging task for current and future spaceborne measurements, which is essential to understand the global hydrological cycle. Recently, the Global Precipitation Measurement (GPM) satellites were launched as a next-generation rainfall mission for observing the global precipitation characteristics. The purpose of the GPM is to enhance the spatiotemporal resolution of global precipitation. The main objective of the present study is to assess the rainfall products from the GPM, especially the Integrated Multi-satellitE Retrievals for the GPM (IMERG) data by comparing with the ground-based observations. The multitemporal scale evaluations of rainfall involving subdaily, diurnal, monthly, and seasonal scales were performed over the Indian subcontinent. The comparison shows that the IMERG performed better than the Tropical Rainfall Measuring Mission (TRMM)-3B42, although both rainfall products underestimated the observed rainfall compared to the ground-based measurements. The analyses also reveal that the TRMM-3B42 and IMERG data sets are able to represent the large-scale monsoon rainfall spatial features but are having region-specific biases. The IMERG shows significant improvement in low rainfall estimates compared to the TRMM-3B42 for selected regions. In the spatial distribution, the IMERG shows higher rain rates compared to the TRMM-3B42, due to its enhanced spatial and temporal resolutions. Apart from this, the characteristics of raindrop size distribution (DSD) obtained from the GPM mission dual-frequency precipitation radar is assessed over the complex mountain terrain site in the Western Ghats, India, using the DSD measured by a Joss-Waldvogel disdrometer.

A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals.

PubMed

Silva, Marina; Oliveira, Marisa; Vieira, Daniel; Brandão, Andreia; Rito, Teresa; Pereira, Joana B; Fraser, Ross M; Hudson, Bob; Gandini, Francesca; Edwards, Ceiridwen; Pala, Maria; Koch, John; Wilson, James F; Pereira, Luísa; Richards, Martin B; Soares, Pedro

2017-03-23

India is a patchwork of tribal and non-tribal populations that speak many different languages from various language families. Indo-European, spoken across northern and central India, and also in Pakistan and Bangladesh, has been frequently connected to the so-called "Indo-Aryan invasions" from Central Asia ~3.5 ka and the establishment of the caste system, but the extent of immigration at this time remains extremely controversial. South India, on the other hand, is dominated by Dravidian languages. India displays a high level of endogamy due to its strict social boundaries, and high genetic drift as a result of long-term isolation which, together with a very complex history, makes the genetic study of Indian populations challenging. We have combined a detailed, high-resolution mitogenome analysis with summaries of autosomal data and Y-chromosome lineages to establish a settlement chronology for the Indian Subcontinent. Maternal lineages document the earliest settlement ~55-65 ka (thousand years ago), and major population shifts in the later Pleistocene that explain previous dating discrepancies and neutrality violation. Whilst current genome-wide analyses conflate all dispersals from Southwest and Central Asia, we were able to tease out from the mitogenome data distinct dispersal episodes dating from between the Last Glacial Maximum to the Bronze Age. Moreover, we found an extremely marked sex bias by comparing the different genetic systems. Maternal lineages primarily reflect earlier, pre-Holocene processes, and paternal lineages predominantly episodes within the last 10 ka. In particular, genetic influx from Central Asia in the Bronze Age was strongly male-driven, consistent with the patriarchal, patrilocal and patrilineal social structure attributed to the inferred pastoralist early Indo-European society. This was part of a much wider process of Indo-European expansion, with an ultimate source in the Pontic-Caspian region, which carried closely related Y

Simultaneous quantification of stevioside and rebaudioside A in different stevia samples collected from the Indian subcontinent

PubMed Central

Chester, Karishma; Tamboli, Ennus T.; Singh, Mhaveer; Ahmad, Sayeed

2012-01-01

Background: A high performance thin layer chromatographic (HPTLC) method was developed for simultaneous estimation of stevioside and rebaudioside A in Stevia rebaudiana samples collected from different regions of Indian subcontinent. Materials and Methods: The separation was achieved by using acetone: ethyl acetate: water (5:4:1, v/v/v) as the solvent system on precoated silica gel 60 F254 TLC plates. The densitometric quantification of stevia glycosides was carried out at wavelength 360 nm in absorption mode after spraying with anisaldehyde sulphuric acid as detecting reagent. Results: The well resolved peaks for stevioside and rebaudioside A were observed at Rf values 0.31± 0.02 and 0.21± 0.02 respectively. The calibration curves were found linear with a wide range of concentration 100 - 2000 ng spot-1 with good correlation coefficient 0.996 and 0.991 for stevioside and rebaudioside A, respectively. Conclusions: The proposed method was validated as per the ICH (International Conferences on Harmonization) guidelines and found simple, sensitive, economic, reproducible, robust and accurate for quantitative analysis of stevia glycosides, which can be applied for quality control of stevia as well as to check. PMID:23248559

Assessment of Unusual Gigantic Jets observed during the Monsoon season: First observations from Indian Subcontinent.

PubMed

Singh, Rajesh; Maurya, Ajeet K; Chanrion, Olivier; Neubert, Torsten; Cummer, Steven A; Mlynarczyk, Janusz; Cohen, Morris B; Siingh, Devendraa; Kumar, Sushil

2017-11-27

Gigantic Jets are electric discharges from thunderstorm cloud tops to the bottom of ionosphere at ~90 km altitude and electrically connect the troposphere and lower ionosphere. Since their first report in 2002, sporadic observations have been reported from ground and space based observations. Here we report first observations of Gigantic Jets in Indian subcontinent over the Indo-Gangetic plains during the monsoon season. Two storms each produced two jets with characteristics not documented so far. Jets propagated ~37 km up remarkably in ~5 ms with velocity of ~7.4 × 10 6 ms -1 and disappeared within ~40-80 ms, which is faster compared to jets reported earlier. The electromagnetic signatures show that they are of negative polarity, transporting net negative charge of ~17-23 C to the lower ionosphere. One jet had an unusual form observed for the first time, which emerged from the leading edge of a slowly drifting complex convective cloud close to the highest regions at ~17 km altitude. A horizontal displacement of ~10 km developed at ~50 km altitude before connecting to the lower ionosphere. Modeling of these Gigantic jets suggests that Gigantic Jets may bend when initiated at the edge of clouds with misaligned vertical charge distribution.

A review on Anopheles culicifacies: from bionomics to control with special reference to Indian subcontinent.

PubMed

Barik, T K; Sahu, B; Swain, V

2009-02-01

Anopheles culicifacies, is a complex of five isomorphic sibling species A, B, C, D and E and is considered to be the major malaria vector in the Indian subcontinent. Despite numerous studies, it is difficult to have a global view of the ecological and bionomical characteristics of the individual sibling species, as different identification methods have been used. Major biological and ecological trends such as the high plasticity of behaviour and the sympatry of species are addressed. In spite of the availability of rapid molecular identification tools, we still lack important information concerning the biological characteristics of each sibling species. Resistance to insecticide is alarming as it has developed quadruple resistance in two states of India. An intensified and appropriate intervention measure to interrupt transmission is the call of the day. The authors focus on (1) reviewing the vectorial aspects of An. culicifacies (2) discussing recently published data on bionomics of each sibling species, (3) identifying lacunae in the understanding of the Culicifacies complex, and (4) exploring the possibility of proper control measures. Our understanding of the bionomics of all the five sibling species would certainly help, keeping in mind the climatic changes we are to face in the next few years.

Species and genetic diversity in the genus Drosophila inhabiting the Indian subcontinent.

PubMed

Singh, Bashisth N

2015-06-01

Biodiversity is the sum total of all living things on the earth with particular reference to the profound variety in structure,function and genetic constitution. It includes both number and frequency of species or genes in a given assemblage and the variety of resulting ecosystems in a region. It is usually considered at three different levels: genetic, species and ecological diversities. Genus Drosophila belongs to the family Drosophilidae (class Insecta, order Diptera), characterized by rich species diversity at global level and also in India, which is a megadiverse country. At global level, more than 1500 species have been described and several thousands estimated. Hawaiian Islands are particularly rich in species diversity with more than 500 species which provides a unique opportunity to study evolution in genus Drosophila. About 150 species of Drosophila have been reported from India. Certain species of Drosophila found in India have been investigated for genetic diversity within the species. In this regard, Drosophila ananassae is noteworthy. It is a cosmopolitan and domestic species with common occurrence in India and is endowed with many genetic peculiarities. Population genetics and evolutionary studies in this species have revealed as to how genetic diversity within a species play an important role in adaptation of populations to varying environments. In addition, the work carried on D. melanogaster, D. nasuta, D. bipectinata and certain other species in India has shown that these species vary in degree and pattern of genetic diversity, and have evolved different mechanisms for adjusting to their environments. The ecological adaptations to various kinds of stress studied in certain species of Drosophila inhabiting the Indian subcontinent are also discussed.

Chemical and structural analysis of gallstones from the Indian subcontinent.

PubMed

Ramana Ramya, J; Thanigai Arul, K; Epple, M; Giebel, U; Guendel-Graber, J; Jayanthi, V; Sharma, M; Rela, M; Narayana Kalkura, S

2017-09-01

Representative gallstones from north and southern parts of India were analyzed by a combination of physicochemical methods: X-ray diffraction (XRD), infrared spectroscopy (IR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), CHNS analysis, thermal analysis and Nuclear Magnetic Resonance (NMR) spectroscopy ( 1 H and 13 C). The stones from north Indian were predominantly consisting of cholesterol monohydrate and anhydrous cholesterol which was confirmed by XRD analysis. FTIR spectroscopy confirmed the presence of cholesterol and calcium bilirubinate in the south Indian gallstones. EDX spectroscopy revealed the presence of carbon, nitrogen, oxygen, calcium, sulfur, sodium and magnesium and chloride in both south Indian and north Indian gallstones. FTIR and NMR spectroscopy confirmed the occurrence of cholesterol in north Indian gallstones. The respective colour of the north Indian and south Indian gallstones was yellowish and black. The morphology of the constituent crystals of the north Indian and south Indian gallstones were platy and globular respectively. The appreciable variation in colour, morphology and composition of south and north Indian gallstones may be due to different food habit and habitat. Copyright © 2017 Elsevier B.V. All rights reserved.

Atmospheric circulation feedback on west Asian dust and Indian monsoon rainfall

NASA Astrophysics Data System (ADS)

Kaskaoutis, Dimitris; Houssos, Elias; Gautam, Ritesh; Singh, Ramesh; Rashki, Alireza; Dumka, Umesh

2016-04-01

Classification of the atmospheric circulation patterns associated with high aerosol loading events over the Ganges valley, via the synergy of Factor and Cluster analysis techniques, has indicated six different synoptic weather patterns, two of which mostly occur during late pre-monsoon and monsoon seasons (May to September). The current study focuses on examining these two specific clusters that are associated with different mean sea level pressure (MSLP), geopotential height at 700 hPa (Z700) and wind fields that seem to affect the aerosol (mostly dust) emissions and precipitation distribution over the Indian sub-continent. Furthermore, the study reveals that enhanced aerosol presence over the Arabian Sea is positively associated with increased rainfall over the Indian landmass. The increased dust over the Arabian Sea and rainfall over India are associated with deepening of the northwestern Indian and Arabian lows that increase thermal convection and convergence of humid air masses into Indian landmass, resulting in larger monsoon precipitation. For this cluster, negative MSLP and Z700 anomalies are observed over the Arabian Peninsula that enhance the dust outflow from Arabia and, concurrently, the southwesterly air flow resulting in increase in monsoon precipitation over India. The daily precipitation over India is found to be positively correlated with the aerosol loading over the Arabian Sea for both weather clusters, thus verifying recent results from satellite observations and model simulations concerning the modulation of the Indian summer monsoon rainfall by the Arabian dust. The present work reveals that in addition to the radiative impacts of dust on modulating the monsoon rainfall, differing weather patterns favor changes in dust emissions, accumulation as well as rainfall distribution over south Asia.

Mitochondrial DNA history of Sri Lankan ethnic people: their relations within the island and with the Indian subcontinental populations.

PubMed

Ranaweera, Lanka; Kaewsutthi, Supannee; Win Tun, Aung; Boonyarit, Hathaichanoke; Poolsuwan, Samerchai; Lertrit, Patcharee

2014-01-01

Located only a short distance off the southernmost shore of the Greater Indian subcontinent, the island of Sri Lanka has long been inhabited by various ethnic populations. Mainly comprising the Vedda, Sinhalese (Up- and Low-country) and Tamil (Sri Lankan and Indian); their history of settlements on the island and the biological relationships among them have remained obscure. It has been hypothesized that the Vedda was probably the earliest inhabitants of the area, followed by Sinhalese and Tamil from the Indian mainland. This study, in which 271 individuals, representing the Sri Lankan ethnic populations mentioned, were typed for their mitochondrial DNA (mtDNA) hypervariable segment 1 (HVS-1) and part of hypervariable segment 2 (HVS-2), provides implications for their settlement history on the island. From the phylogenetic, principal coordinate and analysis of molecular variance results, the Vedda occupied a position separated from all other ethnic people of the island, who formed relatively close affiliations among themselves, suggesting a separate origin of the former. The haplotypes and analysis of molecular variance revealed that Vedda people's mitochondrial sequences are more related to the Sinhalese and Sri Lankan Tamils' than the Indian Tamils' sequences. MtDNA haplogroup analysis revealed that several West Eurasian haplogroups as well as Indian-specific mtDNA clades were found amongst the Sri Lankan populations. Through a comparison with the mtDNA HVS-1 and part of HVS-2 of Indian database, both Tamils and Sinhalese clusters were affiliated with Indian subcontinent populations than Vedda people who are believed to be the native population of the island of Sri Lanka.

Precipitation Seasonality over the Indian Subcontinent: Assessment of Gauge, Reanalyses and Satellite Products

NASA Astrophysics Data System (ADS)

Renwick, J. A.; Rana, S.; McGregor, J.

2015-12-01

This work addresses the seasonal (winter, pre-monsoon, monsoon and post-monsoon) performance of seven precipitation products from three different data sources: gridded station data, satellite-derived data and reanalyses products over the Indian Subcontinent, for a period of 10 years (1997/98 to 2006/07). Precipitation products evaluated are the Asian Precipitation - Highly Resolved Observational Data Integration Towards Evaluation of Water Resources (APHRODITE), the Climate Prediction Center unified gauge (CPC-uni), the Global Precipitation Climatology project (GPCP), Tropical Rainfall Measuring Mission (TRMM) post real-time research products (3B42-V6 and 3B42-V7), the Climate Forecast System Reanalysis (CFSR) and the European Centre for Medium-Range Weather Forecasts (ECMWF) Interim Re-Analysis (ERA-Interim). Several verification measures are employed to assess the accuracy of the data. All datasets capture the large-scale characteristics of the seasonal mean precipitation distribution, albeit with pronounced seasonal and/or regional differences. Compared to APHRODITE, the gauge-only (CPC-uni) and the satellite-derived precipitation products (GPCP, 3B42-V6 and 3B42-V7) capture the summer monsoon rainfall variability better than CFSR and ERA-Interim. Similar conclusions were drawn for the post-monsoon season, with the exception of 3B42-V7, which underestimates post-monsoon precipitation. Over mountainous regions 3B42-V7 shows an appreciable improvement over 3B42-V6 and other gauge-based precipitation products. Significantly large biases/errors occur during the winter months, which is likely related to the uncertainty in observations that artificially inflate the existing error in reanalyses and satellite retrievals.

Collision-induced tectonism along the northwestern margin of the Indian subcontinent as recorded in the Upper Paleocene to Middle Eocene strata of central Pakistan (Kirthar and Sulaiman Ranges)

USGS Publications Warehouse

Warwick, Peter D.; Johnson, Edward A.; Khan, Intizar H.

1998-01-01

Outcrop data from the Upper Paleocene to Middle Eocene Ghazij Formation of central Pakistan provide information about the depositional environments, source areas, and paleogeographic and tectonic settings along the northwestern margin of the Indian subcontinent during the closing of the Tethys Ocean. In this region, in the lower part of the exposed stratigraphic sequence, are various marine carbonate-shelf deposits (Jurassic to Upper Paleocene). Overlying these strata is the Ghazij, which consists of marine mudstone (lower part), paralic sandstone and mudstone (middle part), and terrestrial mudstone and conglomerate (upper part). Petrographic examination of sandstone samples from the middle and upper parts reveals that rock fragments of the underlying carbonate-shelf deposits are dominant; also present are volcanic rock fragments and chromite grains. Paleocurrent measurements from the middle and upper parts suggest that source areas were located northwest of the study area. We postulate that the source areas were uplifted by the collision of the subcontinent with a landmass during the final stages of the closing of the Tethys Ocean. Middle Eocene carbonate-shelf deposits that overlie the Ghazij record a return to marine conditions prior to the Miocene to Pleistocene sediment influx denoting the main collision with Eurasia.

Quantifying Uncertainty in Instantaneous Orbital Data Products of TRMM over Indian Subcontinent

NASA Astrophysics Data System (ADS)

Jayaluxmi, I.; Nagesh, D.

2013-12-01

In the last 20 years, microwave radiometers have taken satellite images of earth's weather proving to be a valuable tool for quantitative estimation of precipitation from space. However, along with the widespread acceptance of microwave based precipitation products, it has also been recognized that they contain large uncertainties. While most of the uncertainty evaluation studies focus on the accuracy of rainfall accumulated over time (e.g., season/year), evaluation of instantaneous rainfall intensities from satellite orbital data products are relatively rare. These instantaneous products are known to potentially cause large uncertainties during real time flood forecasting studies at the watershed scale. Especially over land regions, where the highly varying land surface emissivity offer a myriad of complications hindering accurate rainfall estimation. The error components of orbital data products also tend to interact nonlinearly with hydrologic modeling uncertainty. Keeping these in mind, the present study fosters the development of uncertainty analysis using instantaneous satellite orbital data products (version 7 of 1B11, 2A25, 2A23) derived from the passive and active sensors onboard Tropical Rainfall Measuring Mission (TRMM) satellite, namely TRMM microwave imager (TMI) and Precipitation Radar (PR). The study utilizes 11 years of orbital data from 2002 to 2012 over the Indian subcontinent and examines the influence of various error sources on the convective and stratiform precipitation types. Analysis conducted over the land regions of India investigates three sources of uncertainty in detail. These include 1) Errors due to improper delineation of rainfall signature within microwave footprint (rain/no rain classification), 2) Uncertainty offered by the transfer function linking rainfall with TMI low frequency channels and 3) Sampling errors owing to the narrow swath and infrequent visits of TRMM sensors. Case study results obtained during the Indian summer

Evaluation of haplotype diversity of Achatina fulica (Lissachatina) [Bowdich] from Indian sub-continent by means of 16S rDNA sequence and its phylogenetic relationships with other global populations.

PubMed

Ayyagari, Vijaya Sai; Sreerama, Krupanidhi

2017-08-01

Achatina fulica (Lissachatina fulica) is one of the most invasive species found across the globe causing a significant damage to crops, vegetables, and horticultural plants. This terrestrial snail is native to east Africa and spread to different parts of the world by introductions. India, a hot spot for biodiversity of several endemic gastropods, has witnessed an outburst of this snail population in several parts of the country posing a serious threat to crop loss and also to human health. With an objective to evaluate the genetic diversity of this snail, we have sampled this snail from different parts of India and analyzed its haplotype diversity by means of 16S rDNA sequence information. Apart from this, we have studied the phylogenetic relationships of the isolates sequenced in the present study in relation with other global populations by Bayesian and Maximum-likelihood approaches. Of the isolates sequenced, haplotype 'C' is the predominant one. A new haplotype 'S' from the state of Odisha was observed. The isolates sequenced in the present study clustered with its conspecifics from the Indian sub-continent. Haplotype network analyses were also carried out for studying the evolution of different haplotypes. It was observed that haplotype 'S' was associated with a Mauritius haplotype 'H', indicating the possibility of multiple introductions of A. fulica to India.

On the shortening of Indian summer monsoon season in a warming scenario

NASA Astrophysics Data System (ADS)

Sabeerali, C. T.; Ajayamohan, R. S.

2018-03-01

Assessing the future projections of the length of rainy season (LRS) has paramount societal impact considering its potential to alter the seasonal mean rainfall over the Indian subcontinent. Here, we explored the projections of LRS using both historical and Representative Concentration Pathways 8.5 (RCP8.5) simulations of the Coupled Model Intercomparison Project Phase5 (CMIP5). RCP8.5 simulations project shortening of the LRS of Indian summer monsoon by altering the timing of onset and withdrawal dates. Most CMIP5 RCP8.5 model simulations indicate a faster warming rate over the western tropical Indian Ocean compared to other regions of the Indian Ocean. It is found that the pronounced western Indian Ocean warming and associated increase in convection results in warmer upper troposphere over the Indian Ocean compared to the Indian subcontinent, reducing the meridional gradient in upper tropospheric temperature (UTT) over the Asian summer monsoon (ASM) domain. The weakening of the meridional gradient in UTT induces weakening of easterly vertical wind shear over the ASM domain during first and last phase of monsoon, facilitate delayed (advanced) monsoon onset (withdrawal) dates, ensues the shortening of LRS of the Indian summer monsoon in a warming scenario.

Review of the leafhopper genus Penthimia Germar (Hemiptera: Cicadellidae: Deltocephalinae) from the Indian subcontinent with description of seven new species.

PubMed

Shobharani, M; Viraktamath, C A; Webb, M D

2018-01-02

Species of the leafhopper genus Penthimia Germar known from the Indian subcontinent are reviewed based on the examination of type specimens. Seven new species of the genus, Penthimia curvata sp. nov. (Karnataka: Bandipur), P. meghalayensis sp. nov. (Meghalaya: Nangpoh), P. neoattenuata sp. nov. (India: Tamil Nadu), P. ribhoi sp. nov. (India: Meghalaya), P. sahyadrica sp. nov. (Karnataka: Dharmasthala, Agumbe; Kerala: Thekkady), P. spiculata sp. nov. (Karnataka: Nagarahole) and P. tumida sp. nov. (Tamil Nadu: Ootacamund; Kerala: Munnar) are described. The following nomenclatorial changes are proposed: Penthimia alba Zahniser, McKamey Dmitriev, 2012 (replacement name for P. thoracica Distant, 1918, nec Panzer, 1799), syn. nov. of P. quadrinotata Distant, 1918; Neodartus scutellatus Distant, 1908 syn. nov. of Penthimia ereba Distant 1908; P. nilgiriensis Distant, 1918 syn. nov. of P. montana Distant, 1918; P. scutellata (Distant) comb. nov. (from genus Neodartus); a lectotype is designated for P. maculosa Distant, stat. revived, thereby removing its synonymy with P. scapularis Distant. The following other lectotypes are designated: P. attenuata Distant, P. subniger Distant, P. scapularis Distant, P. distanti Baker, P. ereba Distant, N. scutellatus Distant, P. fraterna Distant, P. funebris Distant, P. juno Distant, P. maculosa Distant, P. montana Distant, P. noctua Distant, P. quadrinotata Distant, P. alba Zahniser, McKamey Dmitriev. Examination of types of Penthimia rufopunctata Motschulsky revealed that it belongs to Penthimia and hence it is transferred back to that genus from Neodartus, revised placement. The following species previously included in the genus Penthimia are transferred to the genera Tambila Distant and Vulturnus Kirkaldy: Tambila badia (Distant) comb. nov., T. majuscula (Distant) comb. nov., T. vittatifrons (Distant) comb. nov., T. variabilis (Distant) comb. nov. and Vulturnus flavocapitata (Distant) comb. nov. Three species are treated in a new

Insecticide resistance status in the whitefly, Bemisia tabaci genetic groups Asia-I, Asia-II-1 and Asia-II-7 on the Indian subcontinent

PubMed Central

Naveen, N. C.; Chaubey, Rahul; Kumar, Dinesh; Rebijith, K. B.; Rajagopal, Raman; Subrahmanyam, B.; Subramanian, S.

2017-01-01

The present study is a summary of the current level of the insecticide resistance to selected organophosphates, pyrethroids, and neonicotinoids in seven Indian field populations of Bemisia tabaci genetic groups Asia-I, Asia-II-1, and Asia-II-7. Susceptibility of these populations was varied with Asia-II-7 being the most susceptible, while Asia-I and Asia-II-1 populations were showing significant resistance to these insecticides. The variability of the LC50 values was 7x for imidacloprid and thiamethoxam, 5x for monocrotophos and 3x for cypermethrin among the Asia-I, while, they were 7x for cypermethrin, 6x for deltamethrin and 5x for imidacloprid within the Asia-II-1 populations. When compared with the most susceptible, PUSA population (Asia-II-7), a substantial increase in resistant ratios was observed in both the populations of Asia-I and Asia-II-1. Comparative analysis during 2010–13 revealed a decline in susceptibility in Asia-I and Asia-II-1 populations of B. tabaci to the tested organophosphate, pyrethroid, and neonicotinoid insecticides. Evidence of potential control failure was detected using probit analysis estimates for cypermethrin, deltamethrin, monocrotophos and imidacloprid. Our results update resistance status of B. tabaci in India. The implications of insecticide resistance management of B. tabaci on Indian subcontinent are discussed. PMID:28098188

Regional distribution of the high-altitude clouds over the Indian subcontinent and surrounding oceanic regions based on seven years of satellite observations

NASA Astrophysics Data System (ADS)

Meenu, S.; Rajeev, K.; Parameswaran, K.; Suresh Raju, C.

2006-12-01

Quantitative estimates of the spatio-temporal variations in deep convective events over the Indian subcontinent, Arabian Sea, Bay of Bengal, and tropical Indian Ocean are carried out using the data obtained from Advanced Very High Resolution Radiometer (AVHRR) onboard NOAA-14 and NOAA-16 during the period 1996-2003. Pixels having thermal IR brightness temperature (BT) less than 245K are considered as high altitude clouds and those having BT<220 K are considered as very high altitude clouds. Very deep convective clouds are observed over north Bay of Bengal during the Asian summer monsoon season when the mean cloud top temperature reaches as low as 190K. Over the Head Bay of Bengal (HBoB) from June to September, more than 50% of the observed clouds are deep convective type and more than half of these deep convective clouds are very deep convective clouds. Histogram analysis of the cloud top temperatures during this period shows that over HBoB the most prominent cloud top temperature of the deep convective clouds is ~205K over the HBoB while that over southeast Arabian Sea (SEAS) is ~220K. This indicates that most probably the cloud top altitude over HBoB is ~2 km larger than that over SEAS during the Asian summer monsoon period. Another remarkable feature observed during the Asian summer monsoon period is the significantly low values of deep convective clouds observed over the south Bay of Bengal close to Srilanka, which appears as a large pool of reduced cloud amount surrounded by regions of large-scale deep convection. Over both SEAS and HBoB, the total, deep convective and very deep convective cloud amounts as well as their corresponding cloud top temperatures (or the altitude of the cloud top) undergo large seasonal variations, while such variations are less prominent over the eastern equatorial Indian Ocean.

Emission, absorption and group delay of microwaves in the atmosphere in relation to water vapour content over the Indian subcontinent

NASA Technical Reports Server (NTRS)

Sen, A. K.; Gupta, A. K. D.; Karmakar, P. K.; Barman, S. D.; Bhattacharya, A. B.; Purkait, N.; Gupta, M. K. D.; Sehra, J. S.

1985-01-01

The advent of satellite communication for global coverage has apparently indicated a renewed interest in the studies of radio wave propagation through the atmosphere, in the VHF, UHF and microwave bands. The extensive measurements of atmosphere constituents, dynamics and radio meterological parameters during the Middle Atmosphere Program (MAP) have opened up further the possibilities of studying tropospheric radio wave propagation parameters, relevant to Earth/space link design. The three basic parameters of significance to radio propagation are thermal emission, absorption and group delay of the atmosphere, all of which are controlled largely by the water vapor content in the atmosphere, particular at microwave bands. As good emitters are also good absorbers, the atmospheric emission as well as the absorption attains a maximum at the frequency of 22.235 GHz, which is the peak of the water vapor line. The group delay is practically independent of frequency in the VHF, UHF and microwave bands. However, all three parameters exhibit a similar seasonal dependence originating presumably from the seasonal dependence of the water vapor content. Some of the interesting results obtained from analyses of radiosonde data over the Indian subcontinent collected by the India Meteorological Department is presented.

High-Resolution Soil Moisture Retrieval using SMAP-L Band Radiometer and RISAT-C band Radar Data for the Indian Subcontinent

NASA Astrophysics Data System (ADS)

Singh, G.; Das, N. N.; Panda, R. K.; Mohanty, B.; Entekhabi, D.; Bhattacharya, B. K.

2016-12-01

Soil moisture status at high resolution (1-10 km) is vital for hydrological, agricultural and hydro-metrological applications. The NASA Soil Moisture Active Passive (SMAP) mission had potential to provide reliable soil moisture estimate at finer spatial resolutions (3 km and 9 km) at the global extent, but suffered a malfunction of its radar, consequently making the SMAP mission observations only from radiometer that are of coarse spatial resolution. At present, the availability of high-resolution soil moisture product is limited, especially in developing countries like India, which greatly depends on agriculture for sustaining a huge population. Therefore, an attempt has been made in the reported study to combine the C-band synthetic aperture radar (SAR) data from Radar Imaging Satellite (RISAT) of the Indian Space Research Organization (ISRO) with the SMAP mission L-band radiometer data to obtain high-resolution (1 km and 3 km) soil moisture estimates. In this study, a downscaling approach (Active-Passive Algorithm) implemented for the SMAP mission was used to disaggregate the SMAP radiometer brightness temperature (Tb) using the fine resolution SAR backscatter (σ0) from RISAT. The downscaled high-resolution Tb was then subjected to tau-omega model in conjunction with high-resolution ancillary data to retrieve soil moisture at 1 and 3 km scale. The retrieved high-resolution soil moisture estimates were then validated with ground based soil moisture measurement under different hydro-climatic regions of India. Initial results show tremendous potential and reasonable accuracy for the retrieved soil moisture at 1 km and 3 km. It is expected that ISRO will implement this approach to produce high-resolution soil moisture estimates for the Indian subcontinent.

Assessment of aerosol indirect effects over Indian subcontinent using long term MODIS aerosol and cloud data

NASA Astrophysics Data System (ADS)

Das, Saurabh; Maitra, Animesh; Saha, Upal; De, Arijit

Aerosols have direct consequences on climate research and in climate change study due to its role in radiative forcing. The modulation of cloud properties due to the presence of aerosol is another important factor in understanding of the climate change scenario. However, the relationship between these two is mostly indirect as the meteorological conditions have a strong impact on the relationship. Cloud effective radius and decreases in precipitation efficiency are interlinked with the increase of aerosols. The net effect is that the cloud liquid water path and cloud lifetime increase with AOD. Though these facts are included in the global climate models (GCM), the quantitative estimation of aerosol indirect efficiency (AIE) varied widely. Some recent studies indicate an increasing trend of the aerosol optical depth over the Indian landmass. The anthropogenic activities are linked with this increase in aerosols. In general, aerosol increase can affect the cloud radius and leads to formation of non-precipitating cloud. However, the chemical composition of aerosols may also be an important factor. It is therefore necessary to have better understanding of the relationship for predicting the future climate which may be affected by such human activities. In this paper, the relation of aerosol optical depth (AOD) with cloud effective radius (CER) has been investigated over the Indian subcontinent using the long term MODIS observations. MODIS can able to provide reliable AOD information over the land surface. It also able to provide information of the cloud effective radius of the same observation point. A grid-wise correlation analysis can thus be performed to estimate the relation between AOD and CER. Result indicates both positive and negative AIE of AOD on CER. To identify the possible reason for such variability in the AIE, the role of anthropogenic aerosols and water vapor is investigated. The study on the efficiency of aerosol indirect effect indicates that a large

Lippia javanica (Burm.f.) Spreng.: Traditional and Commercial Uses and Phytochemical and Pharmacological Significance in the African and Indian Subcontinent

PubMed Central

2017-01-01

Lippia javanica occurs naturally in central, eastern, and southern Africa and has also been recorded in the tropical Indian subcontinent. The potential of L. javanica as herbal or recreational tea and herbal medicine and its associated phytochemistry and biological properties are reviewed. The extensive literature survey revealed that L. javanica is used as herbal tea and has ethnomedicinal applications such as in colds, cough, fever, malaria, wounds, diarrhoea, chest pains, bronchitis, and asthma. Multiple classes of phytochemicals including volatile and nonvolatile secondary metabolites such as alkaloids, amino acids, flavonoids, iridoids, and triterpenes as well as several minerals have been identified from L. javanica. Scientific studies on L. javanica indicate that it has a wide range of pharmacological activities which include anticancer, antiamoebic, antidiabetic, antimalarial, antimicrobial, antioxidant, antiplasmodial, and pesticidal effects. Although many of the traditional uses of L. javanica have been validated by phytochemical and pharmacological studies, there are still some gaps where current knowledge could be improved. Lippia javanica is popular as both herbal and recreational tea, but there is need for more precise studies to evaluate the safety and clinical value of its main active crude and pure compounds and to clarify their mechanisms of action. PMID:28115974

Indian Monsoon Depression: Climatology and Variability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoon, Jin-Ho; Huang, Wan-Ru

The monsoon climate is traditionally characterized by large seasonal rainfall and reversal of wind direction (e.g., Krishnamurti 1979). Most importantly this rainfall is the major source of fresh water to various human activities such as agriculture. The Indian subcontinent resides at the core of the Southeast Asian summer monsoon system, with the monsoon trough extended from northern India across Indochina to the Western Tropical Pacific (WTP). Large fraction of annual rainfall occurs during the summer monsoon season, i.e., June - August with two distinct maxima. One is located over the Bay of Bengal with rainfall extending northwestward into eastern andmore » central India, and the other along the west coast of India where the lower level moist wind meets the Western Ghat Mountains (Saha and Bavardeckar 1976). The rest of the Indian subcontinent receives relatively less rainfall. Various weather systems such as tropical cyclones and weak disturbances contribute to monsoon rainfall (Ramage 1971). Among these systems, the most efficient rain-producing system is known as the Indian monsoon depression (hereafter MD). This MD is critical for monsoon rainfall because: (i) it occurs about six times during each summer monsoon season, (ii) it propagates deeply into the continent and produces large amounts of rainfall along its track, and (iii) about half of the monsoon rainfall is contributed to by the MDs (e.g., Krishnamurti 1979). Therefore, understanding various properties of the MD is a key towards comprehending the veracity of the Indian summer monsoon and especially its hydrological process.« less

Identification of tipping elements of the Indian Summer Monsoon using climate network approach

NASA Astrophysics Data System (ADS)

Stolbova, Veronika; Surovyatkina, Elena; Kurths, Jurgen

2015-04-01

Spatial and temporal variability of the rainfall is a vital question for more than one billion of people inhabiting the Indian subcontinent. Indian Summer Monsoon (ISM) rainfall is crucial for India's economy, social welfare, and environment and large efforts are being put into predicting the Indian Summer Monsoon. For predictability of the ISM, it is crucial to identify tipping elements - regions over the Indian subcontinent which play a key role in the spatial organization of the Indian monsoon system. Here, we use climate network approach for identification of such tipping elements of the ISM. First, we build climate networks of the extreme rainfall, surface air temperature and pressure over the Indian subcontinent for pre-monsoon, monsoon and post-monsoon seasons. We construct network of extreme rainfall event using observational satellite data from 1998 to 2012 from the Tropical Rainfall Measuring Mission (TRMM 3B42V7) and reanalysis gridded daily rainfall data for a time period of 57 years (1951-2007) (Asian Precipitation Highly Resolved Observational Data Integration Towards the Evaluation of Water Resources, APHRODITE). For the network of surface air temperature and pressure fields, we use re-analysis data provided by the National Center for Environmental Prediction and National Center for Atmospheric Research (NCEP/NCAR). Second, we filter out data by coarse-graining the network through network measures, and identify tipping regions of the ISM. Finally, we compare obtained results of the network analysis with surface wind fields and show that occurrence of the tipping elements is mostly caused by monsoonal wind circulation, migration of the Intertropical Convergence Zone (ITCZ) and Westerlies. We conclude that climate network approach enables to select the most informative regions for the ISM, providing realistic description of the ISM dynamics with fewer data, and also help to identify tipping regions of the ISM. Obtained tipping elements deserve a

Dynamics of changing impacts of tropical Indo-Pacific variability on Indian and Australian rainfall

NASA Astrophysics Data System (ADS)

Li, Ziguang; Cai, Wenju; Lin, Xiaopei

2016-08-01

A positive Indian Ocean Dipole (IOD) and a warm phase of the El Niño-Southern Oscillation (ENSO) reduce rainfall over the Indian subcontinent and southern Australia. However, since the 1980s, El Niño’s influence has been decreasing, accompanied by a strengthening in the IOD’s influence on southern Australia but a reversal in the IOD’s influence on the Indian subcontinent. The dynamics are not fully understood. Here we show that a post-1980 weakening in the ENSO-IOD coherence plays a key role. During the pre-1980 high coherence, ENSO drives both the IOD and regional rainfall, and the IOD’s influence cannot manifest itself. During the post-1980 weak coherence, a positive IOD leads to increased Indian rainfall, offsetting the impact from El Niño. Likewise, the post-1980 weak ENSO-IOD coherence means that El Niño’s pathway for influencing southern Australia cannot fully operate, and as positive IOD becomes more independent and more frequent during this period, its influence on southern Australia rainfall strengthens. There is no evidence to support that greenhouse warming plays a part in these decadal fluctuations.

Dynamics of changing impacts of tropical Indo-Pacific variability on Indian and Australian rainfall.

PubMed

Li, Ziguang; Cai, Wenju; Lin, Xiaopei

2016-08-22

A positive Indian Ocean Dipole (IOD) and a warm phase of the El Niño-Southern Oscillation (ENSO) reduce rainfall over the Indian subcontinent and southern Australia. However, since the 1980s, El Niño's influence has been decreasing, accompanied by a strengthening in the IOD's influence on southern Australia but a reversal in the IOD's influence on the Indian subcontinent. The dynamics are not fully understood. Here we show that a post-1980 weakening in the ENSO-IOD coherence plays a key role. During the pre-1980 high coherence, ENSO drives both the IOD and regional rainfall, and the IOD's influence cannot manifest itself. During the post-1980 weak coherence, a positive IOD leads to increased Indian rainfall, offsetting the impact from El Niño. Likewise, the post-1980 weak ENSO-IOD coherence means that El Niño's pathway for influencing southern Australia cannot fully operate, and as positive IOD becomes more independent and more frequent during this period, its influence on southern Australia rainfall strengthens. There is no evidence to support that greenhouse warming plays a part in these decadal fluctuations.

Indian story on semen loss and related Dhat syndrome.

PubMed

Prakash, Om; Kar, Sujit Kumar; Sathyanarayana Rao, T S

2014-10-01

India is a country of many religions and ancient cultures. Indian culture is largely directed by the Vedic culture since time immemorial. Later Indian culture is influenced by Buddhism, Islam, and Christianity. Indian belief system carries the footprints of these cultures. Every culture describes human behaviors and an interpretation of each human behavior is largely influenced by the core cultural belief system. Sexuality is an important domain which is colored by different cultural colors. Like other cultures, Indian culture believes "semen" as the precious body fluid which needs to be preserved. Most Indian beliefs consider loss of semen as a threat to the individual. Ancient Indian literature present semen loss as a negative health related event. Dhat syndrome (related to semen loss) is a culture-bound syndrome seen in the natives of Indian subcontinent. This article gathers the Indian concepts related to semen loss. It also outlines belief systems behind problems of Dhat syndrome.

Indian story on semen loss and related Dhat syndrome

PubMed Central

Prakash, Om; Kar, Sujit Kumar; Sathyanarayana Rao, T. S.

2014-01-01

India is a country of many religions and ancient cultures. Indian culture is largely directed by the Vedic culture since time immemorial. Later Indian culture is influenced by Buddhism, Islam, and Christianity. Indian belief system carries the footprints of these cultures. Every culture describes human behaviors and an interpretation of each human behavior is largely influenced by the core cultural belief system. Sexuality is an important domain which is colored by different cultural colors. Like other cultures, Indian culture believes “semen” as the precious body fluid which needs to be preserved. Most Indian beliefs consider loss of semen as a threat to the individual. Ancient Indian literature present semen loss as a negative health related event. Dhat syndrome (related to semen loss) is a culture-bound syndrome seen in the natives of Indian subcontinent. This article gathers the Indian concepts related to semen loss. It also outlines belief systems behind problems of Dhat syndrome. PMID:25568479

Venous thromboembolism risk and postpartum lying-in: Acculturation of Indian and Chinese women.

PubMed

Melov, Sarah J; Hitos, Kerry

2018-03-01

many cultures have a set time of traditional rest in the postpartum period. There is limited information on how this activity may potentially increase the risk of venous thromboembolism (VTE). We aimed to investigate VTE risk by determining the prevalence of the cultural practice of postpartum "lying-in", quantifying activity and determining the factors that influence this tradition in women from China and the Indian subcontinent (India, Bangladesh, Pakistan and Sri Lanka) at an Australian tertiary referral hospital. we surveyed a prospective cohort of 150 women aged ≥ 18 years who self-identified culturally as from the Indian subcontinent or Chinese, at baseline (≥ 32 weeks gestation) and at follow-up (six to eight weeks postpartum). Demographic details collected included VTE risk factors such as caesarean section, lack of graduated compression stockings (GCS), postpartum haemorrhage greater than 1000mL, comorbidities and immobility. We quantified postpartum activities and investigated factors that might influence inactivity. there were 100 women identifying as from the Indian subcontinent and 50 women identifying as Chinese recruited at the baseline of over 32 weeks' gestation. Most of the study participants (85%) rested in the postpartum period for cultural reasons. Of the women surveyed, 51% rested in bed as much as possible in the postpartum period. We found a significant correlation between increased number of children and decreased overall immobility or rest (P = 0.03). Overall, 91% of participants had relative live-in help, and this significantly increased the risk of immobility by more than six-fold (odds ratio [OR], 6.17; 95% CI, 1.6-23.5; P = 0.008). Furthermore, a vaginal compared to a caesarean birth increased immobility risk by almost 3.5 times (OR, 3.4; 95% CI, 1.20-9.4; P = 0.021). acculturation is highly individualised, however postpartum rest remains prevalent in women who identify themselves culturally as from the Indian subcontinent or as

Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent.

PubMed

Zhang, Xiaoming; Liao, Shiyu; Qi, Xuebin; Liu, Jiewei; Kampuansai, Jatupol; Zhang, Hui; Yang, Zhaohui; Serey, Bun; Sovannary, Tuot; Bunnath, Long; Seang Aun, Hong; Samnom, Ham; Kangwanpong, Daoroong; Shi, Hong; Su, Bing

2015-10-20

Analyses of an Asian-specific Y-chromosome lineage (O2a1-M95)--the dominant paternal lineage in Austro-Asiatic (AA) speaking populations, who are found on both sides of the Bay of Bengal--led to two competing hypothesis of this group's geographic origin and migratory routes. One hypothesis posits the origin of the AA speakers in India and an eastward dispersal to Southeast Asia, while the other places an origin in Southeast Asia with westward dispersal to India. Here, we collected samples of AA-speaking populations from mainland Southeast Asia (MSEA) and southern China, and genotyped 16 Y-STRs of 343 males who belong to the O2a1-M95 lineage. Combining our samples with previous data, we analyzed both the Y-chromosome and mtDNA diversities. We generated a comprehensive picture of the O2a1-M95 lineage in Asia. We demonstrated that the O2a1-M95 lineage originated in the southern East Asia among the Daic-speaking populations ~20-40 thousand years ago and then dispersed southward to Southeast Asia after the Last Glacial Maximum before moving westward to the Indian subcontinent. This migration resulted in the current distribution of this Y-chromosome lineage in the AA-speaking populations. Further analysis of mtDNA diversity showed a different pattern, supporting a previously proposed sex-biased admixture of the AA-speaking populations in India.

Hemostatic interference of Indian king cobra (Ophiophagus hannah) Venom. Comparison with three other snake venoms of the subcontinent.

PubMed

Gowtham, Yashonandana J; Kumar, M S; Girish, K S; Kemparaju, K

2012-06-01

Unlike Naja naja, Bungarus caeruleus, Echis carinatus, and Daboia/Vipera russellii venoms, Ophiophagus hannah venom is medically ignored in the Indian subcontinent. Being the biggest poisonous snake, O. hannah has been presumed to inject several lethal doses of venom in a single bite. Lack of therapeutic antivenom to O. hannah bite in India makes any attempt to save the victim a difficult exercise. This study was initiated to compare O. hannah venom with the above said venoms for possible interference in hemostasis. Ophiophagus hannah venom was found to actively interfere in hemostatic stages such as fibrin clot formation, platelet activation/aggregation, and fibrin clot dissolution. It decreased partial thromboplastin time (aPTT), prothrombin time (PT), and thrombin clotting time (TCT). These activities are similar to that shown by E. carinatus and D. russellii venoms, and thus O. hannah venom was found to exert procoagulant activity through the common pathway of blood coagulation, while N. naja venom increased aPTT and TCT but not PT, and hence it was found to exert anticoagulant activity through the intrinsic pathway. Venoms of O. hannah, E. carinatus, and D. russellii lack plasminogen activation property as they do not hydrolyze azocasein, while they all show plasmin-like activity by degrading the fibrin clot. Although N. naja venom did not degrade azocasein, unlike other venoms, it showed feeble plasmin-like activity on fibrin clot. Venom of E. carinatus induced clotting of human platelet rich plasma (PRP), while the other three venoms interfered in agonist-induced platelet aggregation in PRP. Venom of O. hannah least inhibited the ADP induced platelet aggregation as compared to D. russellii and N. naja venoms. All these three venoms showed complete inhibition of epinephrine-induced aggregation at varied doses. However, O. hannah venom was unique in inhibiting thrombin induced aggregation.

Sustainable Development in Indian Automotive Component Clusters

NASA Astrophysics Data System (ADS)

Bhaskaran, E.

2013-01-01

India is the world's second fastest growing auto market and boasts of the sixth largest automobile industry after China, the US, Germany, Japan and Brazil. The Indian auto component industry recorded its highest year-on-year growth of 34.2 % in 2010-2011, raking in revenue of US 39.9 billion; major contribution coming from exports at US five billion and fresh investment from the US at around US two billion. For inclusive growth and sustainable development most of the auto components manufacturers has adopted the cluster development approach. The objective is to study the technical efficiency (θ), peer weights (λ i ), input slacks (S-) and output slacks (S+) of four Auto Component Clusters (ACC) in India. The methodology adopted is using Data Envelopment Analysis of Input Oriented Banker Charnes Cooper Model by taking number of units and number of employments as inputs and sales and exports in crores as an outputs. The non-zero λ i 's represents the weights for efficient clusters. The S > 0 obtained for one ACC reveals the excess no. of units (S-) and employment (S-) and shortage in sales (S+) and exports (S+). However the variable returns to scale are increasing for three clusters, constant for one more cluster and with nil decrease. To conclude, for inclusive growth and sustainable development, the inefficient ACC should increase their turnover and exports, as decrease in no. of enterprises and employment is practically not possible. Moreover for sustainable development, the ACC should strengthen infrastructure interrelationships, technology interrelationships, procurement interrelationships, production interrelationships and marketing interrelationships to increase productivity and efficiency to compete in the world market.

PTSD in post-road traffic accident patients requiring hospitalization in Indian subcontinent: A review on magnitude of the problem and management guidelines.

PubMed

Undavalli, Chaitanya; Das, Piyush; Dutt, Taru; Bhoi, Sanjeev; Kashyap, Rahul

2014-10-01

Traumatic events after a road traffic accident (RTA) can be physical and/or psychological. Posttraumatic stress disorder (PTSD) is one of the major psychological conditions which affect accident victims. Psychological issues may not be addressed in the emergency department(ED) immediately. There have been reports about a mismatch between the timely referrals from ED to occupational or primary care services for these issues. If left untreated, there may be adverse effects on quality of life (QOL) and work productivity. Hospital expenses, loss of income, and loss of work could create a never ending cycle for financial difficulties and burden in trauma victims. The aim of our review is to address the magnitude of PTSD in post-RTA hospitalized patients in Indian subcontinent population. We also attempted to emphasis on few management guidelines. A comprehensive search was conducted on major databases with Medical Subject Headings (MeSH) term 'PTSD or post-traumatic stress' and Emergency department and vehicle or road or highway or automobile or car or truck or trauma and India. Out of 120 studies, a total of six studies met our inclusion criteria and were included in the review. Our interpretation of the problem is that; hospital expenditure due to trauma, time away from work during hospitalization, and reduction in work performance, are three major hits that can lead RTA victims to financial crisis. Proposed management guidelines are; establish a coordinated triage, implementing a screening tool in the ED, and provide psychological counseling.

Coronary heart disease in Indian Asians.

PubMed

Tan, Sian-Tsung; Scott, William; Panoulas, Vasileios; Sehmi, Joban; Zhang, Weihua; Scott, James; Elliott, Paul; Chambers, John; Kooner, Jaspal S

2014-01-01

The Indian Asian population accounts for a fifth of all global deaths from coronary heart disease (CHD). CHD deaths on the Indian subcontinent have doubled since 1990, and are predicted to rise a further 50% by 2030. Reasons underlying the increased CHD mortality among Indian Asians remain unknown. Although conventional cardiovascular risk factors contribute to CHD in Indian Asians as in other populations, these do not account for their increased risk. Type-2 diabetes, insulin resistance and related metabolic disturbances are more prevalent amongst Indian Asians than Europeans, and have been proposed as major determinants of higher CHD risk among Indian Asians. However, this view is not supported by prospective data. Genome-wide association studies have not identified differences in allele frequencies or effect sizes in known loci to explain the increased CHD risk in Indian Asians. Limited knowledge of mechanisms underlying higher CHD risk amongst Indian Asians presents a major obstacle to reducing the burden of CHD in this population. Systems biology approaches such as genomics, epigenomics, metabolomics and transcriptomics, provide a non-biased approach for discovery of novel biomarkers and disease pathways underlying CHD. Incorporation of these 'omic' approaches in prospective Indian Asian cohorts such as the London Life Sciences Population Study (LOLIPOP) provide an exciting opportunity for the identification of new risk factors underlying CHD in this high risk population.

Molar Tooth Sign with Deranged Liver Function Tests: An Indian Case with COACH Syndrome.

PubMed

Sanjeev, Rama Krishna; Kapoor, Seema; Goyal, Manisha; Kapur, Rajiv; Gleeson, Joseph Gerard

2015-01-01

We report the first genetically proven case of COACH syndrome from the Indian subcontinent in a 6-year-old girl who presented with typical features of Joubert syndrome along with hepatic involvement. Mutation analysis revealed compound heterozygous missense mutation in the known gene TMEM67 (also called MKS3).

Astronomy of Indian Cities, Temples, and Pilgrimage Centers

NASA Astrophysics Data System (ADS)

McKim Malville, J.

Throughout the Indian subcontinent, there are regions where culture and geography join to create a landscape that is infused with meaning and power. These sites are often tirthas, places of extensive mythological associations where many believe that spirit can cross between different realms. Tirthas may be important fords of rivers, summits of hills where the heaven and the earth seem unusually close, or locations where Hindu deities have entered the world. Many contain a symbolic cosmology or visual astronomical sightlines, primarily to the solstices. Two tirthas are discussed: Varanasi, the most important pilgrimage destination for the whole of Hindu India, and Vijayanagara, once a major pilgrimage center of southern India, which became the capital city of the Hindu empire that controlled the southern part of the subcontinent. The concept of self-organized criticality is introduced as a useful technique for analyzing pilgrimage systems.

The earliest settlers' antiquity and evolutionary history of Indian populations: evidence from M2 mtDNA lineage

PubMed Central

2008-01-01

Background The "out of Africa" model postulating single "southern route" dispersal posits arrival of "Anatomically Modern Human" to Indian subcontinent around 66–70 thousand years before present (kyBP). However the contributions and legacy of these earliest settlers in contemporary Indian populations, owing to the complex past population dynamics and later migrations has been an issue of controversy. The high frequency of mitochondrial lineage "M2" consistent with its greater age and distribution suggests that it may represent the phylogenetic signature of earliest settlers. Accordingly, we attempted to re-evaluate the impact and contribution of earliest settlers in shaping the genetic diversity and structure of contemporary Indian populations; using our newly sequenced 72 and 4 published complete mitochondrial genomes of this lineage. Results The M2 lineage, harbouring two deep rooting subclades M2a and M2b encompasses approximately one tenth of the mtDNA pool of studied tribes. The phylogeographic spread and diversity indices of M2 and its subclades among the tribes of different geographic regions and linguistic phyla were investigated in detail. Further the reconstructed demographic history of M2 lineage as a surrogate of earliest settlers' component revealed that the demographic events with pronounced regional variations had played pivotal role in shaping the complex net of populations phylogenetic relationship in Indian subcontinent. Conclusion Our results suggest that tribes of southern and eastern region along with Dravidian and Austro-Asiatic speakers of central India are the modern representatives of earliest settlers of subcontinent. The Last Glacial Maximum aridity and post LGM population growth mechanised some sort of homogeneity and redistribution of earliest settlers' component in India. The demic diffusion of agriculture and associated technologies around 3 kyBP, which might have marginalized hunter-gatherer, is coincidental with the decline of

Implication of vector characteristics of Phlebotomus argentipes in the kala-azar elimination programme in the Indian sub-continent.

PubMed

Chowdhury, Rajib; Kumar, Vijay; Mondal, Dinesh; Das, Murari Lal; Das, Pradeep; Dash, Aditya Prasad; Kroeger, Axel

2016-05-01

Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rainfall, wind speed, relative humidity, soil moisture, pH, and organic carbon are known to influence the oviposition of female sand flies, as well as the survival and development of larvae. However, more detailed knowledge on vector behavior, such as biting times, breeding places, and preferred hosts are needed to design optimal evidence-based vector control interventions. In order to facilitate rational decisions regarding VL vector control, a systematic review was conducted to identify the prevailing practice and knowledge gaps in relation to vector bionomics and behavior. Search terms included 'sand fly bionomics', 'habitat', and 'visceral leishmaniasis/kala-azar vector control' using the Boolean operator AND to identify the country of interest, namely: Bangladesh, India, and Nepal. Both PubMed and Google search engines were used. Additional unpublished documents in the three countries were also analyzed. Information on the life cycle of VL vectors, their breeding behavior, infection rate with L. donovani, feeding behavior, and seasonal variation are useful for designing vector control operations. Unfortunately, none of the studies on the life cycle of P. argentipes was conducted in field settings of the ISC, so the publications from other locations had to be used for determining the duration of life cycle and development from egg to adult. However, information about breeding places, seasonal variation of vector densities, and 47 out of the selected 51 papers are available from the ISC and can be used for intelligent design of control operations. Vector control services should undertake routine insecticide resistance monitoring and adapt indoor residual spraying

Implication of vector characteristics of Phlebotomus argentipes in the kala-azar elimination programme in the Indian sub-continent

PubMed Central

Chowdhury, Rajib; Kumar, Vijay; Mondal, Dinesh; Das, Murari Lal; Das, Pradeep; Dash, Aditya Prasad

2016-01-01

Background Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rainfall, wind speed, relative humidity, soil moisture, pH, and organic carbon are known to influence the oviposition of female sand flies, as well as the survival and development of larvae. However, more detailed knowledge on vector behavior, such as biting times, breeding places, and preferred hosts are needed to design optimal evidence-based vector control interventions. Methods In order to facilitate rational decisions regarding VL vector control, a systematic review was conducted to identify the prevailing practice and knowledge gaps in relation to vector bionomics and behavior. Search terms included ‘sand fly bionomics’, ‘habitat’, and ‘visceral leishmaniasis/kala-azar vector control’ using the Boolean operator AND to identify the country of interest, namely: Bangladesh, India, and Nepal. Both PubMed and Google search engines were used. Additional unpublished documents in the three countries were also analyzed. Results Information on the life cycle of VL vectors, their breeding behavior, infection rate with L. donovani, feeding behavior, and seasonal variation are useful for designing vector control operations. Unfortunately, none of the studies on the life cycle of P. argentipes was conducted in field settings of the ISC, so the publications from other locations had to be used for determining the duration of life cycle and development from egg to adult. However, information about breeding places, seasonal variation of vector densities, and 47 out of the selected 51 papers are available from the ISC and can be used for intelligent design of control operations. Conclusion Vector control services should undertake routine insecticide

Performance of Regional Climate Model in Simulating Monsoon Onset Over Indian Subcontinent

NASA Astrophysics Data System (ADS)

Bhatla, R.; Mandal, B.; Verma, Shruti; Ghosh, Soumik; Mall, R. K.

2018-06-01

The performance of various Convective Parameterization Schemes (CPSs) of Regional Climate Model version 4.3 (RegCM-4.3) for simulation of onset phase of Indian summer monsoon (ISM) over Kerala was studied for the period of 2001-2010. The onset date and its associated spatial variation were simulated using RegCM-4.3 four core CPS, namely Kuo, Tiedtke, Emanuel and Grell; and with two mixed convection schemes Mix98 (Emanuel over land and Grell over ocean) and Mix99 (Grell over land and Emanuel over ocean) on the basis of criteria given by the India Meteorological Department (IMD) (Pai and Rajeevan in Indian summer monsoon onset: variability and prediction. National Climate Centre, India Meteorological Department, 2007). It has been found that out of six CPS, two schemes, namely Tiedtke and Mix99 simulated the onset date properly. The onset phase is characterized with several transition phases of atmosphere. Therefore, to study the thermal response or the effect of different sea surface temperature (SST), namely ERA interim (ERSST) and weekly optimal interpolation (OI_WK SST) on Indian summer monsoon, the role of two different types of SST has been used to investigate the simulated onset date. In addition, spatial atmospheric circulation pattern during onset phase were analyzed using reanalyze dataset of ERA Interim (EIN15) and National Oceanic and Atmospheric Administration (NOAA), respectively, for wind and outgoing long-wave radiation (OLR) pattern. Among the six convective schemes of RegCM-4.3 model, Tiedtke is in good agreement with actual onset dates and OI_WK SST forcing is better for simulating onset of ISM over Kerala.

Independent origins of Indian caste and tribal paternal lineages.

PubMed

Cordaux, Richard; Aunger, Robert; Bentley, Gillian; Nasidze, Ivane; Sirajuddin, S M; Stoneking, Mark

2004-02-03

The origins of the nearly one billion people inhabiting the Indian subcontinent and following the customs of the Hindu caste system are controversial: are they largely derived from Indian local populations (i.e. tribal groups) or from recent immigrants to India? Archaeological and linguistic evidence support the latter hypothesis, whereas recent genetic data seem to favor the former hypothesis. Here, we analyze the most extensive dataset of Indian caste and tribal Y chromosomes to date. We find that caste and tribal groups differ significantly in their haplogroup frequency distributions; caste groups are homogeneous for Y chromosome variation and more closely related to each other and to central Asian groups than to Indian tribal or any other Eurasian groups. We conclude that paternal lineages of Indian caste groups are primarily descended from Indo-European speakers who migrated from central Asia approximately 3,500 years ago. Conversely, paternal lineages of tribal groups are predominantly derived from the original Indian gene pool. We also provide evidence for bidirectional male gene flow between caste and tribal groups. In comparison, caste and tribal groups are homogeneous with respect to mitochondrial DNA variation, which may reflect the sociocultural characteristics of the Indian caste society.

A Lagrangian analysis of cold cloud clusters and their life cycles with satellite observations

PubMed Central

Esmaili, Rebekah Bradley; Tian, Yudong; Vila, Daniel Alejandro; Kim, Kyu-Myong

2018-01-01

Cloud movement and evolution signify the complex water and energy transport in the atmosphere-ocean-land system. Detecting, clustering, and tracking clouds as semi-coherent cluster objects enables study of their evolution which can complement climate model simulations and enhance satellite retrieval algorithms, where there are large gaps between overpasses. Using an area-overlap cluster tracking algorithm, in this study we examine the trajectories, horizontal extent, and brightness temperature variations of millions of individual cloud clusters over their lifespan, from infrared satellite observations at 30-minute, 4-km resolution, for a period of 11 years. We found that the majority of cold clouds were both small and short-lived and that their frequency and location are influenced by El Niño. More importantly, this large sample of individually tracked clouds shows their horizontal size and temperature evolution. Longer lived clusters tended to achieve their temperature and size maturity milestones at different times, while these stages often occurred simultaneously in shorter lived clusters. On average, clusters with this lag also exhibited a greater rainfall contribution than those where minimum temperature and maximum size stages occurred simultaneously. Furthermore, by examining the diurnal cycle of cluster development over Africa and the Indian subcontinent, we observed differences in the local timing of the maximum occurrence at different life cycle stages. Over land there was a strong diurnal peak in the afternoon while over the ocean there was a semi-diurnal peak composed of longer-lived clusters in the early morning hours and shorter-lived clusters in the afternoon. Building on regional specific work, this study provides a long-term, high-resolution, and global survey of object-based cloud characteristics. PMID:29744257

A Lagrangian analysis of cold cloud clusters and their life cycles with satellite observations.

PubMed

Esmaili, Rebekah Bradley; Tian, Yudong; Vila, Daniel Alejandro; Kim, Kyu-Myong

2016-10-16

Cloud movement and evolution signify the complex water and energy transport in the atmosphere-ocean-land system. Detecting, clustering, and tracking clouds as semi-coherent cluster objects enables study of their evolution which can complement climate model simulations and enhance satellite retrieval algorithms, where there are large gaps between overpasses. Using an area-overlap cluster tracking algorithm, in this study we examine the trajectories, horizontal extent, and brightness temperature variations of millions of individual cloud clusters over their lifespan, from infrared satellite observations at 30-minute, 4-km resolution, for a period of 11 years. We found that the majority of cold clouds were both small and short-lived and that their frequency and location are influenced by El Niño. More importantly, this large sample of individually tracked clouds shows their horizontal size and temperature evolution. Longer lived clusters tended to achieve their temperature and size maturity milestones at different times, while these stages often occurred simultaneously in shorter lived clusters. On average, clusters with this lag also exhibited a greater rainfall contribution than those where minimum temperature and maximum size stages occurred simultaneously. Furthermore, by examining the diurnal cycle of cluster development over Africa and the Indian subcontinent, we observed differences in the local timing of the maximum occurrence at different life cycle stages. Over land there was a strong diurnal peak in the afternoon while over the ocean there was a semi-diurnal peak composed of longer-lived clusters in the early morning hours and shorter-lived clusters in the afternoon. Building on regional specific work, this study provides a long-term, high-resolution, and global survey of object-based cloud characteristics.

A Lagrangian Analysis of Cold Cloud Clusters and Their Life Cycles With Satellite Observations

NASA Technical Reports Server (NTRS)

Esmaili, Rebekah Bradley; Tian, Yudong; Vila, Daniel Alejandro; Kim, Kyu-Myong

2016-01-01

Cloud movement and evolution signify the complex water and energy transport in the atmosphere-ocean-land system. Detecting, clustering, and tracking clouds as semi coherent cluster objects enables study of their evolution which can complement climate model simulations and enhance satellite retrieval algorithms, where there are large gaps between overpasses. Using an area-overlap cluster tracking algorithm, in this study we examine the trajectories, horizontal extent, and brightness temperature variations of millions of individual cloud clusters over their lifespan, from infrared satellite observations at 30-minute, 4-km resolution, for a period of 11 years. We found that the majority of cold clouds were both small and short-lived and that their frequency and location are influenced by El Nino. More importantly, this large sample of individually tracked clouds shows their horizontal size and temperature evolution. Longer lived clusters tended to achieve their temperature and size maturity milestones at different times, while these stages often occurred simultaneously in shorter lived clusters. On average, clusters with this lag also exhibited a greater rainfall contribution than those where minimum temperature and maximum size stages occurred simultaneously. Furthermore, by examining the diurnal cycle of cluster development over Africa and the Indian subcontinent, we observed differences in the local timing of the maximum occurrence at different life cycle stages. Over land there was a strong diurnal peak in the afternoon while over the ocean there was a semi-diurnal peak composed of longer-lived clusters in the early morning hours and shorter-lived clusters in the afternoon. Building on regional specific work, this study provides a long-term, high-resolution, and global survey of object-based cloud characteristics.

Gondwana to Asia: Plate tectonics, paleogeography and the biological connectivity of the Indian sub-continent from the Middle Jurassic through latest Eocene (166 35 Ma)

NASA Astrophysics Data System (ADS)

Ali, Jason R.; Aitchison, Jonathan C.

2008-06-01

Using the most up-to-the-date information available, we present a considerably revised plate tectonic and paleogeographic model for the Indian Ocean bordering continents, from Gondwana's Middle Jurassic break-up through to India's collision with Asia in the middle Cenozoic. The landmass framework is then used to explore the sometimes complex and occasionally counter-intuitive patterns that have been observed in the fossil and extant biological records of India, Madagascar, Africa and eastern Eurasia, as well those of the more distal continents. Although the paleogeographic model confirms the traditional view that India became progressively more isolated from the major landmasses during the Cretaceous and Paleocene, it is likely that at various times minor physiographic features (principally ocean islands) provided causeways and/or stepping-stone trails along which land animals could have migrated to/from the sub-continent. Aside from a likely link (albeit broken by several marine gaps) to Africa for much of this time (it is notable, that the present-day/recent biota of Madagascar indicates that the ancestors of five land-mammal orders, plus bats, crossed the > 400-km-wide Mozambique Channel at different times in the Cenozoic), it is possible that the Kerguelen Plateau connected India and Australia-Antarctica in the mid-Cretaceous (approximately 115-90 Ma). Later, the Seychelles-Mascarene Plateau and nearby elevated sea-floor areas could have allowed faunas to pass between southern India and Madagascar in the Late Cretaceous, from around 85-65 Ma, with an early Cenozoic extension to this path forming as a result of the Reunion hot-spot trace islands growing on the ocean floor to the SSW of India. The modelling also suggests that India's northward passage towards Asia, with eventual collision at 35 Ma, involved the NE corner of the sub-continent making a glancing contact with Sumatra, followed by Burma from ~ 57 Ma (late Paleocene) onwards, a scenario which is

Pharmacologic overview of Withania somnifera, the Indian Ginseng.

PubMed

Dar, Nawab John; Hamid, Abid; Ahmad, Muzamil

2015-12-01

Withania somnifera, also called 'Indian ginseng', is an important medicinal plant of the Indian subcontinent. It is widely used, singly or in combination, with other herbs against many ailments in Indian Systems of Medicine since time immemorial. Withania somnifera contains a spectrum of diverse phytochemicals enabling it to have a broad range of biological implications. In preclinical studies, it has shown anti-microbial, anti-inflammatory, anti-tumor, anti-stress, neuroprotective, cardioprotective, and anti-diabetic properties. Additionally, it has demonstrated the ability to reduce reactive oxygen species, modulate mitochondrial function, regulate apoptosis, and reduce inflammation and enhance endothelial function. In view of these pharmacologic properties, W. somnifera is a potential drug candidate to treat various clinical conditions, particularly related to the nervous system. In this review, we summarize the pharmacologic characteristics and discuss the mechanisms of action and potential therapeutic applications of the plant and its active constituents.

Use of microwave satellite data to study variations in rainfall over the Indian Ocean

NASA Technical Reports Server (NTRS)

Hinton, Barry B.; Martin, David W.; Auvine, Brian; Olson, William S.

1990-01-01

The University of Wisconsin Space Science and Engineering Center mapped rainfall over the Indian Ocean using a newly developed Scanning Multichannel Microwave Radiometer (SMMR) rain-retrieval algorithm. The short-range objective was to characterize the distribution and variability of Indian Ocean rainfall on seasonal and annual scales. In the long-range, the objective is to clarify differences between land and marine regimes of monsoon rain. Researchers developed a semi-empirical algorithm for retrieving Indian Ocean rainfall. Tools for this development have come from radiative transfer and cloud liquid water models. Where possible, ground truth information from available radars was used in development and testing. SMMR rainfalls were also compared with Indian Ocean gauge rainfalls. Final Indian Ocean maps were produced for months, seasons, and years and interpreted in terms of historical analysis over the sub-continent.

Mechanisms for the intraseasonal variability of tropospheric ozone over the Indian Ocean during the winter monsoon

NASA Astrophysics Data System (ADS)

Chatfield, R. B.; Guan, H.; Thompson, A. M.; Smit, H. G. J.

2007-05-01

We synthesize daily sonde (vertical) information and daily satellite (horizontal) information to provide an empirical description of ozone origins over the northern Indian Ocean during the INDOEX (Indian Ocean Experiment) field campaign (February-March 1999). This area is shown to be a significant portion of the "high-ozone tropics". East-west O3 features and their flow are identified, and ozone origins are compared to other tropical regions, using water vapor as a second tracer. In the study period, multiple processes contribute to O3 column enhancements, their importance varying strongly by latitude: (1) Low-altitude O3 pollution over the northern Indian Ocean mainly originates from the Indian subcontinent and is traceable to high emission areas. Convective activity south of Sri Lanka helps direct ozone outflow from the northern Indian subcontinent. (2) Middle tropospheric O3 maxima over the northern Indian Ocean originate from various sources, often transitioning within a few hours. Convective venting of Asian pollutants can add 20-30 ppbv to the middle troposphere at 5°N-10°N, alternating with stratospheric influence. (3) A number of cases suggest that strong mixing-in of stratospheric air along the subtropical jet raised tropospheric O3 in early March by ˜40-50 ppbv, especially poleward of ˜10°N. (4) Influences of lightning and large-scale biomass burning were not strong during this period, in contrast to the situation in Africa and the South Atlantic or locally in Southeast Asia. This work illustrates successes and limitations in approaches to synthesizing disparate information on trace-gas distributions taken from satellite retrieval products and ozonesondes.

Mechanisms for the Intraseasonal Variability of Tropospheric Ozone over the Indian Ocean during the Winter Monsoon

NASA Technical Reports Server (NTRS)

Chatfield, R. b.; Guan, H.; Thompson, A. M.; Smit, H. G. J.

2007-01-01

We synthesize daily sonde (vertical) information and daily satellite (horizontal) information to provide an empirical description of ozone origins over the northern Indian Ocean during the INDOEX (Indian Ocean Experiment) field campaign (February-March 1999). This area is shown to be a significant portion of the "high-ozone tropics". East-west O3 features and their flow are identified, and ozone origins are compared to other tropical regions, using water vapor as a second tracer. In the study period, multiple processes contribute to O3 column enhancements, their importance varying strongly by latitude: (1) Low-altitude O3 pollution over the northern Indian Ocean mainly originates from the Indian subcontinent and is traceable to high emission areas. Convective activity south of Sri Lanka helps direct ozone outflow from the northern Indian subcontinent. (2) Middle tropospheric O3 maxima over the northern Indian Ocean originate from various sources, often transitioning within a few hours. Convective venting of Asian pollutants can add 20-30 ppbv to the middle troposphere at 5degN-10degN, alternating with stratospheric influence. (3) A number of cases suggest that strong mixing-in of stratospheric air along the subtropical jet raised tropospheric O3 in early March by approx.40-50 ppbv, especially poleward of approx. 10degN. (4) Influences of lightning and large-scale biomass burning were not strong during this period, in contrast to the situation in Africa and the South Atlantic or locally in Southeast Asia. This work illustrates successes and limitations in approaches to synthesizing disparate information on trace-gas distributions taken from satellite retrieval products and ozonesondes.

Indian Ocean and Indian summer monsoon: relationships without ENSO in ocean-atmosphere coupled simulations

NASA Astrophysics Data System (ADS)

Crétat, Julien; Terray, Pascal; Masson, Sébastien; Sooraj, K. P.; Roxy, Mathew Koll

2017-08-01

The relationship between the Indian Ocean and the Indian summer monsoon (ISM) and their respective influence over the Indo-Western North Pacific (WNP) region are examined in the absence of El Niño Southern Oscillation (ENSO) in two partially decoupled global experiments. ENSO is removed by nudging the tropical Pacific simulated sea surface temperature (SST) toward SST climatology from either observations or a fully coupled control run. The control reasonably captures the observed relationships between ENSO, ISM and the Indian Ocean Dipole (IOD). Despite weaker amplitude, IODs do exist in the absence of ENSO and are triggered by a boreal spring ocean-atmosphere coupled mode over the South-East Indian Ocean similar to that found in the presence of ENSO. These pure IODs significantly affect the tropical Indian Ocean throughout boreal summer, inducing a significant modulation of both the local Walker and Hadley cells. This meridional circulation is masked in the presence of ENSO. However, these pure IODs do not significantly influence the Indian subcontinent rainfall despite overestimated SST variability in the eastern equatorial Indian Ocean compared to observations. On the other hand, they promote a late summer cross-equatorial quadrupole rainfall pattern linking the tropical Indian Ocean with the WNP, inducing important zonal shifts of the Walker circulation despite the absence of ENSO. Surprisingly, the interannual ISM rainfall variability is barely modified and the Indian Ocean does not force the monsoon circulation when ENSO is removed. On the contrary, the monsoon circulation significantly forces the Arabian Sea and Bay of Bengal SSTs, while its connection with the western tropical Indian Ocean is clearly driven by ENSO in our numerical framework. Convection and diabatic heating associated with above-normal ISM induce a strong response over the WNP, even in the absence of ENSO, favoring moisture convergence over India.

High prevalence of inflammatory bowel disease in United States residents of Indian ancestry.

PubMed

Malhotra, Reenu; Turner, Kevin; Sonnenberg, Amnon; Genta, Robert M

2015-04-01

It is unclear whether the reported low prevalence of inflammatory bowel disease (IBD) in Southern and Eastern Asia is real (caused by genetic or environmental factors) or spurious (because of differences in awareness of the condition among physicians or different interpretations of endoscopic and histologic features). We aimed to estimate the prevalence of IBD in patients of different ethnicities who underwent endoscopy in the United States, with ileocolonic biopsies evaluated by a single group of gastrointestinal pathologists. We used a national pathology database to collect data on 1,027,977 subjects who underwent colonoscopy with ileocolonic biopsies from January 2008 through December 2013 throughout the United States; mucosal biopsy specimens were evaluated and reported by 1 group of 35 histopathologists. Patients were stratified into the following ancestries: Indian (persons with ancestry in the Indian subcontinent), East Asian (China, Korea, Japan, and Vietnam), Hispanic, Jewish, and Other. The prevalence of ulcerative colitis (UC), Crohn's disease (CD), and indeterminate colitis was determined for each ethnic group. In the study population, 30,812 patients were diagnosed with IBD (20,308 with UC, 7706 with CD, and 2798 with indeterminate colitis). UC was more commonly associated with Indian and Jewish ethnicity and less commonly associated with East Asian and Hispanic ethnicity. Similar patterns also applied to CD and to all types of IBD analyzed jointly. Among Indian patients, 11.7% of those of Gujarati origins had IBD, compared with 7.9% of other Indians (odds ratio, 1.5; 95% confidence interval, 1.14-2.11). Patients of Indian origin living in the United States have a greater risk for all types of IBD than other American populations. East Asians and Hispanics have a lower risk, possibly similar to that of the populations still living in their original countries. These findings may have relevance to the practice of gastroenterology in countries where there

Understanding of the Regional Aerosol Characterization over the North-eastern part of the Indian Subcontinent: South-Asian Region

NASA Astrophysics Data System (ADS)

Dahutia, P.; Pathak, B.

2016-12-01

The north-eastern region (NER) of India is a part of Indian subcontinent owing a unique topography surrounded by three sides by high mountain and open in the west. The long-term characterization of aerosol and its effect on climate is carried out in 11 locations over NER of India along with two adjoining locations Dhaka (DAC) and Banmauk (BNK) (22-30°N and 88-98°E) using multiple satellite retrievals and model data. Quality assured monthly Level 3 Collection 6 data of MODerate Resolution Imaging Spectroradiometer (MODIS) data retrieved from both Aqua and Terra having 1°×1° resolution of columnar Aerosol Optical Depth (AOD) and its associated parameters for the period of 2001-2014. Investigation revealed a distinct spatio-temporal variation over all the locations with highest climatological mean AOD in Dhaka (0.66±0.19) and lowest in high altitude location Thimphu (0.17±0.1). The parameter Absorbing aerosols Index (AAI) from combine TOMS and OMI instrument is used to study absorbing aerosols during 1979-2014. The seasonal AOD and AAI are highest during pre-monsoon months while lowest in retreating monsoon in all the locations. The continuous wavelet transform (CWT) analysis of non-smoothen time-series of AOD revealed the strong annual oscillation (AO) of total columnar aerosol loading. The annual trend analysis of aerosol parameters shows a statistically significant (i.e., p<0.05) increasing trends of AOD ( 0.009-0.001year-1) as well as AAI ( 0.015-0.001year-1) over all locations. The simultaneous increase in Angtröm Exponent (AE) along with AOD and AAI indicates the enhancement of anthropogenic aerosols which might have a contribution to the climate change. The performed long-term (1979-2014) regression analysis of seasonal and annual mean of Net Surface Downward Shortwave Flux (NSDSF), Cloud Optical Depth (COD), rainfall and temperature shows a signature of climate change over this region. The opposite trend of COD (increasing) and NSDSF (decreasing

Extensive Variation and Sub-Structuring in Lineage A mtDNA in Indian Sheep: Genetic Evidence for Domestication of Sheep in India

PubMed Central

Singh, Sachin; Kumar Jr, Satish; Kolte, Atul P.; Kumar, Satish

2013-01-01

Previous studies on mitochondrial DNA analysis of sheep from different regions of the world have revealed the presence of two major- A and B, and three minor- C, D and E maternal lineages. Lineage A is more frequent in Asia and lineage B is more abundant in regions other than Asia. We have analyzed mitochondrial DNA sequences of 330 sheep from 12 different breeds of India. Neighbor-joining analysis revealed lineage A, B and C in Indian sheep. Surprisingly, multidimensional scaling plot based on FST values of control region of mtDNA sequences showed significant breed differentiation in contrast to poor geographical structuring reported earlier in this species. The breed differentiation in Indian sheep was essentially due to variable contribution of two major lineages to different breeds, and sub- structuring of lineage A, possibly the latter resulting from genetic drift. Nucleotide diversity of this lineage was higher in Indian sheep (0.014 ± 0.007) as compared to that of sheep from other regions of the world (0.009 ± 0.005 to 0.01 ± 0.005). Reduced median network analysis of control region and cytochrome b gene sequences of Indian sheep when analyzed along with available published sequences of sheep from other regions of the world showed that several haplotypes of lineage A were exclusive to Indian sheep. Given the high nucleotide diversity in Indian sheep and the poor sharing of lineage A haplotypes between Indian and non-Indian sheep, we propose that lineage A sheep has also been domesticated in the east of Near East, possibly in Indian sub-continent. Finally, our data provide support that lineage B and additional lineage A haplotypes of sheep might have been introduced to Indian sub-continent from Near East, probably by ancient sea trade route. PMID:24244282

Indian Monsoon Rainfall Variability During the Common Era: Implications on the Ancient Civilization

NASA Astrophysics Data System (ADS)

Pothuri, D.

2017-12-01

Indian monsoon rainfall variability was reconstructed during last two millennia by using the δ18Ow from a sediment core in the Krishna-Godavari Basin. Higher δ18Ow values during Dark Age Cold Period (DACP) (1550 to 1250 years BP) and Little Ice Age (LIA) (700 to 200 years BP) represent less Indian monsoon rainfall. Whereas during Medieval Warm Period (MWP) (1200 to 800 years BP) and major portion of Roman Warm Period (RWP) 2000 to 1550 years BP) document more rainfall in the Indian subcontinent as evident from lower δ18Ow values. A significant correlation exist between the Bay of Bengal (BoB) sea surface temperature (SST) and Indian monsoon proxy (i.e. δ18Ow), which suggests that; (i) the forcing mechanism of the Indian monsoon rainfall variability during last two millennia was controlled by the thermal contrast between the Indian Ocean and Asian Land Mass, and (ii) the evaporation processes in the BoB and associated SST are strongly coupled with the Indian Monsoon variability over the last two millennia.

Global Phylogeny of Mycobacterium tuberculosis Based on Single Nucleotide Polymorphism (SNP) Analysis: Insights into Tuberculosis Evolution, Phylogenetic Accuracy of Other DNA Fingerprinting Systems, and Recommendations for a Minimal Standard SNP Set†

PubMed Central

Filliol, Ingrid; Motiwala, Alifiya S.; Cavatore, Magali; Qi, Weihong; Hazbón, Manzour Hernando; Bobadilla del Valle, Miriam; Fyfe, Janet; García-García, Lourdes; Rastogi, Nalin; Sola, Christophe; Zozio, Thierry; Guerrero, Marta Inírida; León, Clara Inés; Crabtree, Jonathan; Angiuoli, Sam; Eisenach, Kathleen D.; Durmaz, Riza; Joloba, Moses L.; Rendón, Adrian; Sifuentes-Osornio, José; Ponce de León, Alfredo; Cave, M. Donald; Fleischmann, Robert; Whittam, Thomas S.; Alland, David

2006-01-01

We analyzed a global collection of Mycobacterium tuberculosis strains using 212 single nucleotide polymorphism (SNP) markers. SNP nucleotide diversity was high (average across all SNPs, 0.19), and 96% of the SNP locus pairs were in complete linkage disequilibrium. Cluster analyses identified six deeply branching, phylogenetically distinct SNP cluster groups (SCGs) and five subgroups. The SCGs were strongly associated with the geographical origin of the M. tuberculosis samples and the birthplace of the human hosts. The most ancestral cluster (SCG-1) predominated in patients from the Indian subcontinent, while SCG-1 and another ancestral cluster (SCG-2) predominated in patients from East Asia, suggesting that M. tuberculosis first arose in the Indian subcontinent and spread worldwide through East Asia. Restricted SCG diversity and the prevalence of less ancestral SCGs in indigenous populations in Uganda and Mexico suggested a more recent introduction of M. tuberculosis into these regions. The East African Indian and Beijing spoligotypes were concordant with SCG-1 and SCG-2, respectively; X and Central Asian spoligotypes were also associated with one SCG or subgroup combination. Other clades had less consistent associations with SCGs. Mycobacterial interspersed repetitive unit (MIRU) analysis provided less robust phylogenetic information, and only 6 of the 12 MIRU microsatellite loci were highly differentiated between SCGs as measured by GST. Finally, an algorithm was devised to identify two minimal sets of either 45 or 6 SNPs that could be used in future investigations to enable global collaborations for studies on evolution, strain differentiation, and biological differences of M. tuberculosis. PMID:16385065

Programme of Indian Centre for Space Physics using Very Low Frequency Radio Waves

NASA Astrophysics Data System (ADS)

Chakrabarti, Sandip Kumar; Sasmal, Sudipta; Pal, Sujay; Kanta Maji, Surya; Ray, Suman

Indian Centre for Space Physics conducted two major VLF campaigns all over Indian Sub-continent to study the propagation effects of VLF radio waves. It made multi-receiver observations during solar eclipse. ICSP not only recorded multitudes of solar flares, it also reproduced VLF observation from ab initio calculation. ICSP extended its study to the field of earthquake predictions using signal anomalies and using case by case studies as well as statistical analysis, showed that anomalies are real and more studies are required to understand them. Using earth as a gigantic detector, it detected ionospheric perturbations due to soft gamma-ray repeaters and gamma-ray bursts.

Timing and Nature of Appearance of C4 Plants in the Indian Subcontinent: Clue from Isotopic Ratios of Biomarker

NASA Astrophysics Data System (ADS)

Sanyal, P.

2014-12-01

Appearance and expansion of C4 plants during the late Miocene was first documented from Siwalik Group of sediments using carbon isotope ratio of soil carbonates. It was proposed that C4 plants appeared drastically in response to change in hydrological cycle. Subsequently, various workers documented evolution and expansion of C4 plants from different Siwalik sections of India, Nepal and Pakistan. Although evolution and expansion of C4 plants was documented in all these studies but nature and timing of expansion of C4 plants showed variations from section to sections. Even from same section, the results varied with change in proxies. The hydrological changes also differ regionally. One of the reasons of differences in results was lack of modern data set from the Indian subcontinent. For example, in many cases δ18O values of New Delhi rainwater has been considered as reference data set and applied to site of investigation with some corrections. The average δ13C values of C3 and C4 plants was considered as -27‰ and -12.5‰ respectively, but modern C3 plants in the Gangetic plain is almost 2.5‰ lower than the value used in those studies. Additional problem raised as preservation of pristine isotopic character of soil organic matter is also apprehensive. To resolve all these issues, the δ13C value of long chain alkane have been used to reconstruct C3-C4 plants after isotopic characterization of modern plants and their biomarker from the Gangetic plain which is equivalent to the past Siwalik flood plain. Additionally, δD values of long chain alkane were also measured. Variations of d13C values of long chain alkane with time show presence of C4 plants in Siwalik from 11 Ma ago and since then gradual increase in C4 plants till 6 Ma followed by a sharp increase. The statistically significant correlation between δD and δ13C values of long chain alkane show that positive impact of hydrological change on abundance of C3-C4 plants.

Alu polymorphic insertions reveal genetic structure of north Indian populations.

PubMed

Tripathi, Manorama; Tripathi, Piyush; Chauhan, Ugam Kumari; Herrera, Rene J; Agrawal, Suraksha

2008-10-01

The Indian subcontinent is characterized by the ancestral and cultural diversity of its people. Genetic input from several unique source populations and from the unique social architecture provided by the caste system has shaped the current genetic landscape of India. In the present study 200 individuals each from three upper-caste and four middle-caste Hindu groups and from two Muslim populations in North India were examined for 10 polymorphic Alu insertions (PAIs). The investigated PAIs exhibit high levels of polymorphism and average heterozygosity. Limited interpopulation variance and genetic flow in the present study suggest admixture. The results of this study demonstrate that, contrary to common belief, the caste system has not provided an impermeable barrier to genetic exchange among Indian groups.

Reconstructing the Indian Origin and Dispersal of the European Roma: A Maternal Genetic Perspective

PubMed Central

Mendizabal, Isabel; Valente, Cristina; Gusmão, Alfredo; Alves, Cíntia; Gomes, Verónica; Goios, Ana; Parson, Walther; Calafell, Francesc; Alvarez, Luis; Amorim, António; Gusmão, Leonor

2011-01-01

Previous genetic, anthropological and linguistic studies have shown that Roma (Gypsies) constitute a founder population dispersed throughout Europe whose origins might be traced to the Indian subcontinent. Linguistic and anthropological evidence point to Indo-Aryan ethnic groups from North-western India as the ancestral parental population of Roma. Recently, a strong genetic hint supporting this theory came from a study of a private mutation causing primary congenital glaucoma. In the present study, complete mitochondrial control sequences of Iberian Roma and previously published maternal lineages of other European Roma were analyzed in order to establish the genetic affinities among Roma groups, determine the degree of admixture with neighbouring populations, infer the migration routes followed since the first arrival to Europe, and survey the origin of Roma within the Indian subcontinent. Our results show that the maternal lineage composition in the Roma groups follows a pattern of different migration routes, with several founder effects, and low effective population sizes along their dispersal. Our data allowed the confirmation of a North/West migration route shared by Polish, Lithuanian and Iberian Roma. Additionally, eleven Roma founder lineages were identified and degrees of admixture with host populations were estimated. Finally, the comparison with an extensive database of Indian sequences allowed us to identify the Punjab state, in North-western India, as the putative ancestral homeland of the European Roma, in agreement with previous linguistic and anthropological studies. PMID:21264345

Indian Independence and the Question of Pakistan. [Student Text and] Teacher Resource Book. Choices for the 21st Century.

ERIC Educational Resources Information Center

Fox, Sarah Cleveland

This document includes a student text and a teacher resource book. The student booklet provides an overview of the history of the Indian subcontinent, focuses on key events leading up to partition, and explores the origins of the conflict in Kashmir. It notes that to understand the conflict in Kashmir, people must examine the period of British…

Effect of village-wide use of long-lasting insecticidal nets on visceral Leishmaniasis vectors in India and Nepal: a cluster randomized trial.

PubMed

Picado, Albert; Das, Murari L; Kumar, Vijay; Kesari, Shreekant; Dinesh, Diwakar S; Roy, Lalita; Rijal, Suman; Das, Pradeep; Rowland, Mark; Sundar, Shyam; Coosemans, Marc; Boelaert, Marleen; Davies, Clive R

2010-01-26

Visceral leishmaniasis (VL) control in the Indian subcontinent is currently based on case detection and treatment, and on vector control using indoor residual spraying (IRS). The use of long-lasting insecticidal nets (LN) has been postulated as an alternative or complement to IRS. Here we tested the impact of comprehensive distribution of LN on the density of Phlebotomus argentipes in VL-endemic villages. A cluster-randomized controlled trial with household P. argentipes density as outcome was designed. Twelve clusters from an ongoing LN clinical trial--three intervention and three control clusters in both India and Nepal--were selected on the basis of accessibility and VL incidence. Ten houses per cluster selected on the basis of high pre-intervention P. argentipes density were monitored monthly for 12 months after distribution of LN using CDC light traps (LT) and mouth aspiration methods. Ten cattle sheds per cluster were also monitored by aspiration. A random effect linear regression model showed that the cluster-wide distribution of LNs significantly reduced the P. argentipes density/house by 24.9% (95% CI 1.80%-42.5%) as measured by means of LTs. The ongoing clinical trial, designed to measure the impact of LNs on VL incidence, will confirm whether LNs should be adopted as a control strategy in the regional VL elimination programs. The entomological evidence described here provides some evidence that LNs could be usefully deployed as part of the VL control program. ClinicalTrials.gov CT-2005-015374.

A cross-sectional comparative study of gut bacterial community of Indian and Finnish children.

PubMed

Kumbhare, Shreyas V; Kumar, Himanshu; Chowdhury, Somak P; Dhotre, Dhiraj P; Endo, Akihito; Mättö, Jaana; Ouwehand, Arthur C; Rautava, Samuli; Joshi, Ruchi; Patil, Nitinkumar P; Patil, Ravindra H; Isolauri, Erika; Bavdekar, Ashish R; Salminen, Seppo; Shouche, Yogesh S

2017-09-05

The human gut microbiome plays a crucial role in the compositional development of gut microbiota. Though well documented in western pediatrics population, little is known about how various host conditions affect populations in different geographic locations such as the Indian subcontinent. Given the impact of distinct environmental conditions, our study assess the gut bacterial diversity of a small cohort of Indian and Finnish children and investigated the influence of FUT2 secretor status and birth mode on the gut microbiome of these populations. Using multiple profiling techniques, we show that the gut bacterial community structure in 13-14-year-old Indian (n = 47) and Finnish (n = 52) children differs significantly. Specifically, Finnish children possessed higher Blautia and Bifidobacterium, while genera Prevotella and Megasphaera were predominant in Indian children. Our study also demonstrates a strong influence of FUT2 and birth mode variants on specific gut bacterial taxa, influence of which was noticed to differ between the two populations under study.

Profiling of Human Acquired Immunity Against the Salivary Proteins of Phlebotomus papatasi Reveals Clusters of Differential Immunoreactivity

PubMed Central

Geraci, Nicholas S.; Mukbel, Rami M.; Kemp, Michael T.; Wadsworth, Mariha N.; Lesho, Emil; Stayback, Gwen M.; Champion, Matthew M.; Bernard, Megan A.; Abo-Shehada, Mahmoud; Coutinho-Abreu, Iliano V.; Ramalho-Ortigão, Marcelo; Hanafi, Hanafi A.; Fawaz, Emadeldin Y.; El-Hossary, Shabaan S.; Wortmann, Glenn; Hoel, David F.; McDowell, Mary Ann

2014-01-01

Phlebotomus papatasi sand flies are among the primary vectors of Leishmania major parasites from Morocco to the Indian subcontinent and from southern Europe to central and eastern Africa. Antibody-based immunity to sand fly salivary gland proteins in human populations remains a complex contextual problem that is not yet fully understood. We profiled the immunoreactivities of plasma antibodies to sand fly salivary gland sonicates (SGSs) from 229 human blood donors residing in different regions of sand fly endemicity throughout Jordan and Egypt as well as 69 US military personnel, who were differentially exposed to P. papatasi bites and L. major infections in Iraq. Compared with plasma from control region donors, antibodies were significantly immunoreactive to five salivary proteins (12, 26, 30, 38, and 44 kDa) among Jordanian and Egyptian donors, with immunoglobulin G4 being the dominant anti-SGS isotype. US personnel were significantly immunoreactive to only two salivary proteins (38 and 14 kDa). Using k-means clustering, donors were segregated into four clusters distinguished by unique immunoreactivity profiles to varying combinations of the significantly immunogenic salivary proteins. SGS-induced cellular proliferation was diminished among donors residing in sand fly-endemic regions. These data provide a clearer picture of human immune responses to sand fly vector salivary constituents. PMID:24615125

The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste Populations

PubMed Central

Kivisild, T.; Rootsi, S.; Metspalu, M.; Mastana, S.; Kaldma, K.; Parik, J.; Metspalu, E.; Adojaan, M.; Tolk, H.-V.; Stepanov, V.; Gölge, M.; Usanga, E.; Papiha, S. S.; Cinnioğlu, C.; King, R.; Cavalli-Sforza, L.; Underhill, P. A.; Villems, R.

2003-01-01

Two tribal groups from southern India—the Chenchus and Koyas—were analyzed for variation in mitochondrial DNA (mtDNA), the Y chromosome, and one autosomal locus and were compared with six caste groups from different parts of India, as well as with western and central Asians. In mtDNA phylogenetic analyses, the Chenchus and Koyas coalesce at Indian-specific branches of haplogroups M and N that cover populations of different social rank from all over the subcontinent. Coalescence times suggest early late Pleistocene settlement of southern Asia and suggest that there has not been total replacement of these settlers by later migrations. H, L, and R2 are the major Indian Y-chromosomal haplogroups that occur both in castes and in tribal populations and are rarely found outside the subcontinent. Haplogroup R1a, previously associated with the putative Indo-Aryan invasion, was found at its highest frequency in Punjab but also at a relatively high frequency (26%) in the Chenchu tribe. This finding, together with the higher R1a-associated short tandem repeat diversity in India and Iran compared with Europe and central Asia, suggests that southern and western Asia might be the source of this haplogroup. Haplotype frequencies of the MX1 locus of chromosome 21 distinguish Koyas and Chenchus, along with Indian caste groups, from European and eastern Asian populations. Taken together, these results show that Indian tribal and caste populations derive largely from the same genetic heritage of Pleistocene southern and western Asians and have received limited gene flow from external regions since the Holocene. The phylogeography of the primal mtDNA and Y-chromosome founders suggests that these southern Asian Pleistocene coastal settlers from Africa would have provided the inocula for the subsequent differentiation of the distinctive eastern and western Eurasian gene pools. PMID:12536373

Small bowel morphology in British Indian and Afro-Caribbean subjects: evidence of tropical enteropathy.

PubMed Central

Wood, G M; Gearty, J C; Cooper, B T

1991-01-01

Distal duodenal biopsy specimens taken from 30 white, 35 Indian, and 20 Afro-Caribbean residents of West Birmingham during routine endoscopy for dyspepsia, were assessed by dissecting microscopy and morphometry. Finger-shaped villi were significantly less frequent in the Indian and Afro-Caribbean subjects than in the white subjects when assessed by dissecting microscopy (p less than 0.005), and both immigrant groups had decreased mucosal thickness (p less than 0.01), villous height (p less than 0.001), villous:crypt ratios (p less than 0.01) and enterocyte height (p less than 0.05) compared with the white group. In the Indian subjects, villous height and villous:crypt ratios correlated significantly with the time since the last visit to the Indian subcontinent (p less than 0.005). Serum alkaline phosphatase values were significantly higher in the Indian subjects compared with the whites (p less than 0.02), and serum globulins were increased in both the Afro-Caribbean and Indian subjects (p less than 0.01). There were no correlations between morphometric indices and body habitus or biochemical or haematological indices and the long term effect of the morphological changes is not clear. PMID:2013420

Rainfall seasonality on the Indian subcontinent during the Cretaceous greenhouse.

PubMed

Ghosh, Prosenjit; Prasanna, K; Banerjee, Yogaraj; Williams, Ian S; Gagan, Michael K; Chaudhuri, Atanu; Suwas, Satyam

2018-05-31

The Cretaceous greenhouse climate was accompanied by major changes in Earth's hydrological cycle, but seasonally resolved hydroclimatic reconstructions for this anomalously warm period are rare. We measured the δ 18 O and CO 2 clumped isotope Δ 47 of the seasonal growth bands in carbonate shells of the mollusc Villorita cyprinoides (Black Clam) growing in the Cochin estuary, in southern India. These tandem records accurately reconstruct seasonal changes in sea surface temperature (SST) and seawater δ 18 O, allowing us to document freshwater discharge into the estuary, and make inferences about rainfall amount. The same analytical approach was applied to well-preserved fossil remains of the Cretaceous (Early Maastrichtian) mollusc Phygraea (Phygraea) vesicularis from the nearby Kallankuruchchi Formation in the Cauvery Basin of southern India. The palaeoenvironmental record shows that, unlike present-day India, where summer rainfall predominates, most rainfall in Cretaceous India occurred in winter. During the Early Maastrichtian, the Indian plate was positioned at ~30°S latitude, where present-day rainfall and storm activity is also concentrated in winter. The good match of the Cretaceous climate and present-day climate at ~30°S suggests that the large-scale atmospheric circulation and seasonal hydroclimate patterns were similar to, although probably more intense than, those at present.

Potential impact of the May Southern Hemisphere annular mode on the Indian summer monsoon rainfall

NASA Astrophysics Data System (ADS)

Dou, Juan; Wu, Zhiwei; Zhou, Yefan

2017-04-01

El Niño-Southern Oscillation (ENSO) is probably a most important external forcing to Indian summer monsoon (ISM) rainfall (ISMR), yet the observed ENSO-ISMR relationship has become weak in recent years. It's essential to explore other predominant modes of variability which can contribute to the ISMR. As the leading mode of the variability in Southern Hemisphere (SH) extratropical atmospheric circulation, the SH annular mode (SAM) has potential influence both on the northern and southern hemispheric climate. The present study investigates the relationship between the SAM and ISMR. It is found that the May SAM exhibits a significant positive correlation with the monsoon precipitation over the Indian sub-continent and the adjacent areas in JunetJuly (JJ). Observational and numerical evidences indicate that the May SAM anomaly can trigger a South Indian Ocean dipole (SIOD) sea surface temperature anomaly (SSTA) through air-sea interactions. The SIOD SSTA persisting into the following months of JJ excites abnormal meridional circulation and modulates the low-level cross-equatorial flow. Accordingly, the ascending (or descending) motion and water vapor transportation are enhanced (or suppressed), which favors more (or less) precipitation over the Indian sub-continent and the adjacent areas. In fact, the SIOD SSTA plays an "ocean bridge" role to "prolong" the influence of the May SAM to the subsequent season and in turn impacts on the ISMR. Moreover, an empirical model is established to forecast the JJ ISMR strength based on the ENSO, Indian Ocean Dipole (IOD) and May SAM. The hindcast is carried out for the period 1979-2014, and performs better than the multimodel ensemble mean (MME) obtained from the Development of a European MME system for seasonal to interannual prediction (DEMETER) project. Since all these predictors can be monitored in real time before the early boreal summer, the empirical model might provide a practical real-time forecast tool for predicting ISMR

Potential impact of the May Southern Hemisphere annular mode on the Indian summer monsoon rainfall

NASA Astrophysics Data System (ADS)

Dou, Juan; Wu, Zhiwei; Zhou, Yefan

2017-08-01

El Niño-Southern Oscillation (ENSO) is probably a most important external forcing to Indian summer monsoon (ISM) rainfall (ISMR), yet the observed ENSO-ISMR relationship has become weak in recent years. It's essential to explore other predominant modes of variability which can contribute to the ISMR. As the leading mode of the variability in Southern Hemisphere (SH) extratropical atmospheric circulation, the SH annular mode (SAM) has potential influence both on the northern and southern hemispheric climate. The present study investigates the relationship between the SAM and ISMR. It is found that the May SAM exhibits a significant positive correlation with the monsoon precipitation over the Indian sub-continent and the adjacent areas in June-July (JJ). Observational and numerical evidences indicate that the May SAM anomaly can trigger a South Indian Ocean dipole (SIOD) sea surface temperature anomaly (SSTA) through air-sea interactions. The SIOD SSTA persisting into the following months of JJ excites abnormal meridional circulation and modulates the low-level cross-equatorial flow. Accordingly, the ascending (or descending) motion and water vapor transportation are enhanced (or suppressed), which favors more (or less) precipitation over the Indian sub-continent and the adjacent areas. In fact, the SIOD SSTA plays an "ocean bridge" role to "prolong" the influence of the May SAM to the subsequent season and in turn impacts on the ISMR. Moreover, an empirical model is established to forecast the JJ ISMR strength based on the ENSO, Indian Ocean Dipole and May SAM. The hindcast is carried out for the period 1979-2014, and performs better than the multimodel ensemble mean (MME) obtained from the Development of a European MME system for seasonal to interannual prediction (DEMETER) project. Since all these predictors can be monitored in real time before the early boreal summer, the empirical model might provide a practical real-time forecast tool for predicting ISMR

Anisotropy in the lowermost mantle beneath the Indian Ocean Geoid Low from ScS splitting measurements

NASA Astrophysics Data System (ADS)

Padma Rao, B.; Ravi Kumar, M.; Singh, Arun

2017-02-01

The Indian Ocean Geoid Low (IOGL) to the south of Indian subcontinent is the world's largest geoid anomaly. In this study, we investigate the seismic anisotropy of the lowermost mantle beneath the IOGL by analyzing splitting of high-quality ScS phases corrected for source and receiver side upper mantle anisotropy. Results reveal significant anisotropy (˜1.01%) in the D'' layer. The observed fast axis polarization azimuths in the ray coordinate system indicate a TTI (transverse isotropy with a tilted axis of symmetry) style of anisotropy. Lattice Preferred Orientation (LPO) deformation of the palaeo-subducted slabs experiencing high shear strain is a plausible explanation for the observed anisotropy beneath the IOGL.

The great Indian haze revisited: aerosol distribution effects on microphysical and optical properties of warm clouds over peninsular India

NASA Astrophysics Data System (ADS)

Ghanti, R.; Ghosh, S.

2010-03-01

The Indian subcontinent is undergoing a phase of rapid urbanisation. Inevitable fallout of this process is a concomitant increase in air pollution much of which can be attributed to the infamous great Indian haze phenomena. One observes that the aerosol size distributions vary considerably along the Bay of Bengal (BOB), Arabian Sea (AS) and the Indian Ocean (IO), although, the dynamical attributes are very similar, particularly over the BOB and the AS during this season. Unlike major European studies (e.g. Aerosol Characterization Experiment-2, Ghosh et al., 2005), there are no cloud microphysical modelling studies to complement these observational results for the Indian sub-continent. Ours is the first modelling study over this important region where a time-tested model (O'Dowd et al., 1999a; Ghosh et al., 2007; Rap et al., 2009) is used to obtain cloud microphysical and optical properties from observed aerosol size distributions. Un-activated aerosol particles and very small cloud droplets have to be treated specially to account for non-ideal effects-our model does this effectively yielding realistic estimate of cloud droplet number concentrations (Nc). Empirical relationships linking aerosol concentration to (Nc) yield a disproportionately higher Nc suggesting that such empirical formulations should be used with caution. Our modelling study reveals that the cloud's microphysical and optical properties are very similar along the AS and the BOB despite them having disparate dry aerosol spectral distributions. This is non-intuitive, as one would expect changes in microphysical development with widely different aerosol distributions. There is some increase in cloud droplet numbers with increased haze concentrations but much less than a simple proportion would indicate.

Characteristics, management, and outcomes of spontaneous osteonecrosis of the knee in Indian population.

PubMed

Bhatnagar, Nishit; Sharma, Siddharth; Gautam, Virender Kumar; Kumar, Ajeet; Tiwari, Anurag

2018-03-18

Spontaneous osteonecrosis of the knee affects the medial femoral condyle in patients above 55 years of age. Many reports and studies are available from western countries. But there is a gross paucity of literature on spontaneous osteonecrosis of the knee (SPONK) in the Indian subcontinent, either it is under-reported or detected at a later stage. The aim of our study was to detect SPONK in Indian population and describe its characteristics, treatment, and outcome. A prospective study was conducted over a period of three years. All patients above 18 years with knee pain at rest and medial condyle tenderness without joint laxity were evaluated with plain radiographs and MRI. Further tests were done if radiological signs of osteonecrosis were present. Various parameters were recoded like Visual Analog Scale (VAS), Knee Society Score (KSS), and MRI Osteoarthritis Knee Score. Conservative treatment consisted of a combination of NSAIDs and bisphosphonates. Decompression with bone grafting was done if there was no improvement or deterioration at three month follow-up. Ten patients were diagnosed with SPONK. The mean age was 50 years with male predominance (60%) with the involvement of medial femoral condyle (80%) or left knee (70%). Most cases were in Koshino stage 1. Mean VAS was 6.5 and mean KSS was 59. All clinical parameters showed improvement at one year. A study with a bigger sample size and longer follow-up is needed to fill the lacunae of literature on this topic from the Indian subcontinent. In spite of the limitations, we did observe that in our population, males were more commonly affected than females, which is contrary to most studies on the subject. Also, the disease had an early age of onset (50 years) in Indian population as compared to Western and East Asian populations. Combined therapy of NSAIDs and bisphosphonates shows excellent results over a period of one year. Joint-preserving surgeries are effective even in Koshino stage 3 SPONK.

More-frequent extreme northward shifts of eastern Indian Ocean tropical convergence under greenhouse warming

PubMed Central

Weller, Evan; Cai, Wenju; Min, Seung-Ki; Wu, Lixin; Ashok, Karumuri; Yamagata, Toshio

2014-01-01

The Intertropical Convergence Zone (ITCZ) in the tropical eastern Indian Ocean exhibits strong interannual variability, often co-occurring with positive Indian Ocean Dipole (pIOD) events. During what we identify as an extreme ITCZ event, a drastic northward shift of atmospheric convection coincides with an anomalously strong north-minus-south sea surface temperature (SST) gradient over the eastern equatorial Indian Ocean. Such shifts lead to severe droughts over the maritime continent and surrounding islands but also devastating floods in southern parts of the Indian subcontinent. Understanding future changes of the ITCZ is therefore of major scientific and socioeconomic interest. Here we find a more-than-doubling in the frequency of extreme ITCZ events under greenhouse warming, estimated from climate models participating in the Coupled Model Intercomparison Project phase 5 that are able to simulate such events. The increase is due to a mean state change with an enhanced north-minus-south SST gradient and a weakened Walker Circulation, facilitating smaller perturbations to shift the ITCZ northwards. PMID:25124737

Southern Oscillation in surface circulation and climate over the tropical Atlantic, eastern Pacific, and Indian Oceans as captured by cluster analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolter, K.

Clusters of sea level pressure (SLP), surface wind, cloudiness, and sea surface temperature (SST) in the domain of the tropical Atlantic, eastern Pacific, and Indian Oceans are introduced and discussed in terms of general circulation and climate. They appear to capture well the large-scale degrees of freedom of the seasonal fields. In the Atlantic, and, to a lesser extent, in the eastern Pacific, most analyzed fields group into zonally oriented trade wind clusters. These are separated distinctly by the near-equatorial trough axis. By contrast, the Indian Ocean features strong interhemispheric connections associations with the monsoon systems of boreal summer and,more » to a lesser degree, of boreal winter. The usefulness of clusters thus established is elucidated with respect to the Southern Oscillation (SO). General circulation changes associated with this planetary pressure seesaw are deduced from the correlation maps of surface field clusters for January/February and July/August. During the positive SO phase (i.e., anomalously high pressure over the eastern Pacific and anomalously low pressure over Indonesia), both the Atlantic and eastern Pacific near-equatorial troughs are inferred to be shifted towards the north from July/August SLP, wind, and cloudiness fields. While eastern Pacific trade winds are weakened in both seasons in the positive PO phase, the Atlantic trades appear strengthened at the same time in the winter hemisphere only. Over the Indian Ocean, the monsoon circulation seems to be strengthened during the positive SO phase, with the summer monsoon displaying a more complex picture. Its SLP, cloudiness, and SST fields support an enhanced southwest monsoon, while its surface winds appear largely inconclusive. SST is lowered during the positive SO phase in all three tropical oceans.« less

Cross-reactivity and neutralization of Indian King cobra (Ophiophagus hannah) venom by polyvalent and monovalent antivenoms.

PubMed

Gowtham, Yashonandana J; Mahadeswaraswamy, Y H; Girish, K S; K, Kemparaju

2014-07-01

The venom of the largest venomous snake, the king cobra (Ophiophagus hannah), is still out of league for the production of therapeutic polyvalent antivenom nor it is characterized immunologically in the Indian subcontinent. In the present study, the king cobra venom is comparatively studied for the cross-reactivity/reactivity and toxicity neutralization by the locally available equine therapeutic polyvalent BSV and VB antivenoms, and monovalent antivenom (OH-IgG) prepared in rabbit. None of the two therapeutic antivenoms procured from two different firms showed any signs of cross-reactivity in terms of antigen-antibody precipitin lines in immunodouble diffusion assay; however, a weak and an insignificant cross-reactivity pattern was observed in ELISA and Western blot studies. Further, both BSV and VB antivenoms failed to neutralize proteolytic, hyaluronidase and phospholipase activities as well as toxic properties such as edema, myotoxicity and lethality of the venom. As expected, OH-IgG showed strong reactivity in immunodouble diffusion, ELISA and in Western blot analysis and also neutralized both enzyme activities as well as the toxic properties of the venom. Thus, the study provides insight into the likely measures that are to be taken in cases of accidental king cobra bites for which the Indian subcontinent is still not prepared for. Copyright © 2014 Elsevier B.V. All rights reserved.

Cow urine, Indian yellow, and art forgeries: An update.

PubMed

Smith, Gregory Dale

2017-07-01

In a recent technical note in this Journal, de Faria et al., 2017 [1] reported the Raman spectrum of authentic Indian yellow artists' pigment, correcting a decades old reference spectrum that has led to the misidentification of this pigment in artworks that actually contained tartrazine yellow. The present communication provides additional information and corrects important experimental details mentioned by de Faria et al. that should lead to further identifications of the authentic pigment in artworks. Despite their claim that the analysis of this naturally fluorescent colorant is only possible with Fourier transform (FT) instruments, the ready characterization of two authentic samples of historic Indian yellow pigment is demonstrated here using commonly available visible and near-infrared excitation sources on a dispersive Raman microspectrometer. To highlight the importance of the proper identification of dyes and colorants, the authentication and art historical implications of previous literature reports that have misidentified Indian yellow on historic documents are more thoroughly discussed here from a forensic science point of view. The numerous modern pigments that are sold as imitation Indian yellow are addressed and analyzed, allowing the ready noninvasive detection of anachronistic colorants in attempted forgeries. Finally, this unusual pigment is positively identified for the first time using non-invasive dispersive Raman microspectroscopy on a historic object of uncertain date, a highly decorative manuscript from the Indian subcontinent. Copyright © 2017 Elsevier B.V. All rights reserved.

Genetic evidence on the origins of Indian caste populations.

PubMed

Bamshad, M; Kivisild, T; Watkins, W S; Dixon, M E; Ricker, C E; Rao, B B; Naidu, J M; Prasad, B V; Reddy, P G; Rasanayagam, A; Papiha, S S; Villems, R; Redd, A J; Hammer, M F; Nguyen, S V; Carroll, M L; Batzer, M A; Jorde, L B

2001-06-01

The origins and affinities of the approximately 1 billion people living on the subcontinent of India have long been contested. This is owing, in part, to the many different waves of immigrants that have influenced the genetic structure of India. In the most recent of these waves, Indo-European-speaking people from West Eurasia entered India from the Northwest and diffused throughout the subcontinent. They purportedly admixed with or displaced indigenous Dravidic-speaking populations. Subsequently they may have established the Hindu caste system and placed themselves primarily in castes of higher rank. To explore the impact of West Eurasians on contemporary Indian caste populations, we compared mtDNA (400 bp of hypervariable region 1 and 14 restriction site polymorphisms) and Y-chromosome (20 biallelic polymorphisms and 5 short tandem repeats) variation in approximately 265 males from eight castes of different rank to approximately 750 Africans, Asians, Europeans, and other Indians. For maternally inherited mtDNA, each caste is most similar to Asians. However, 20%-30% of Indian mtDNA haplotypes belong to West Eurasian haplogroups, and the frequency of these haplotypes is proportional to caste rank, the highest frequency of West Eurasian haplotypes being found in the upper castes. In contrast, for paternally inherited Y-chromosome variation each caste is more similar to Europeans than to Asians. Moreover, the affinity to Europeans is proportionate to caste rank, the upper castes being most similar to Europeans, particularly East Europeans. These findings are consistent with greater West Eurasian male admixture with castes of higher rank. Nevertheless, the mitochondrial genome and the Y chromosome each represents only a single haploid locus and is more susceptible to large stochastic variation, bottlenecks, and selective sweeps. Thus, to increase the power of our analysis, we assayed 40 independent, biparentally inherited autosomal loci (1 LINE-1 and 39 Alu elements

Career Cluster Activity Book, Intermediate Level. Learn About the Fifteen Career Clusters and Color the Pictures.

ERIC Educational Resources Information Center

White Hawk, Sharon, Ed.

Simple black and white illustrations portray one occupation for each of 15 career clusters. Directed toward the Indian student and showing Indians at work in the occupations depicted, the illustrations are intended to create an awareness, understanding, and motivation for Indian students to become involved in work, both on and off the reservation.…

Exploring domestic violence and social distress in Australian-Indian migrants through community theater.

PubMed

O'Connor, Manjula; Colucci, Erminia

2016-02-01

In many parts of the world, young adult women have higher levels of common mental disorders than men. The exacerbation of domestic violence (DV) by migration is a salient social determinant of poor mental health. Ecological models describe factors contributing to DV as operating at individual, family, cultural, and societal levels. We explored the interplay among these factors in an Indian community living in Melbourne, Australia, in a qualitative participatory action research study using a modified Forum Theater approach. We here present findings on connections between migration, societal factors, and social/family/cultural factors in DV. The study captured the voices of women living in the community as they describe how DV contributes to their emotional difficulties. Improved understanding of the sociocultural dynamics of DV and the associated social distress in this migrant Indian community can be used to guide the development of culturally sensitive prevention and response programs to assist migrant women from the Indian subcontinent who present with psychopathology and suicidal behaviors associated with DV. © The Author(s) 2015.

Young Vs Old Colorectal Cancer in Indian Subcontinent: a Tertiary Care Center Experience.

PubMed

Pokharkar, Ashish B; Bhandare, Manish; Patil, Prachi; Mehta, Shaesta; Engineer, Reena; Saklani, Avanish P

2017-12-01

This study aims to compare patient, tumor, treatment-related factors and survival between young (<45 years) and old (>45 years) Indian colorectal cancer (CRC) patients. Total 778 patients of CRC were registered at tertiary cancer center in India between 1 August 2013 and 31 July 2014. Patients were followed up for median period of 27.73 months. Data regarding patient, tumor, treatment and survival-related factors were collected. Patients were divided in young (≤45 years) and old (>45 years) age groups. Statistical analysis was done with SPSS software version 23. Young age group patients presented more commonly with poor histology, node-positive disease, and rectal site. Younger age group patients received multiple lines of neoadjuvant treatment. There was no significant overall survival difference in both groups of patients. On stratified stage-wise analysis, no significant overall survival (OS) difference was found between two groups (young vs old-1- and 3-year OS: 85.2 and 61.5% vs 81.5 and 64.5%, respectively; P  = 0.881). On univariate analysis, gender, performance status, site, stage, differentiation, TRG, CRM status, signet ring type, and CEA level were significant prognostic factors. In disease-free survival (DFS) analysis, it is found that there is statistically significant difference in DFS (young vs old: 1 and 3 years; 77.6 and 62.8% vs 85.8 and 74.1%, respectively; P value, 0.02), but when OS was analyzed for same group of patient, there was no statistical difference ( P  = 0.302). This study confirms the high incidence rates of CRC in young Indian patients. There is no OS difference between two age groups. In operated group of patients, there is higher DFS in older patients but no OS advantage at 3 years follow-up. Further long-term follow-up is required to see any OS difference.

Association of Intact dupA (dupA1) rather than dupA1 cluster with duodenal ulcer in Indian population.

PubMed

Alam, Jawed; Ghosh, Prachetash; Ganguly, Mou; Sarkar, Avijit; De, Ronita; Mukhopadhyay, Asish K

2015-01-01

The duodenal ulcer promoting gene (dupA) and dupA cluster in Helicobacter pylori have been described as a risk factor for duodenal ulcer development in some populations. Polymorphic gene dupA can be divided into two groups, intact dupA1 (long or short type based on the presence or absence of 615-bp extra sequences at the 5' region) having complete reading frame and other truncated dupA2 having frame-shift mutation. This study was aimed to elucidate the role of dupA of H. pylori and their clusters in the disease manifestation of Indian population. A total of 170 H. pylori strains were screened for the presence of dupA, dupA alleles and dupA cluster by PCR and sequencing. Pro-inflammatory cytokine (IL-8) with different dupA variant H. pylori stimulated gastric epithelial cells (AGS cells) was measured by ELISA. A total of 50 strains (29.4%) were positive for dupA among the tested 170 strains. The prevalence of dupA1 in duodenal ulcer (DU) and non-ulcer dyspepsia (NUD) populations was found to be 25.5% (25/98) and 11.1% (8/72), respectively and 16.4% (28/170) of the tested strains had dupA1, cagA and vacAs1m1 positive. The distribution of long and short type dupA1 has not been significantly associated with the disease outcome. The dupA cluster analysis showed that 10.2% (10/98) and 8.3% (6/72) strains were positive among DU and NUD, respectively. IL-8 production was significantly higher in dupA1(+) , cagA (+), vacA (+) (902.5 ± 79.01 pg/mL) than dupA2 (+) , cagA (+) , vacA (+) (536.0 ± 100.4 pg/mL, P = 0.008) and dupA (-), cagA (+), vacA (+) (549.7 ± 104.1 pg/mL, P = 0.009). Phylogenetic analysis of dupA indicated that the Indian H. pylori strains clustered with East Asian strains but distinct from Western strains. This is the first known genetic element of Indian H. pylori that is genetically closer to the East Asian strains but differed from the Western strains. The intact dupA1 was significantly associated with DU than NUD (P = 0

Climate change: The challenges for public health preparedness and response- An Indian case study.

PubMed

Patil, Rajan R; Deepa, T M

2007-09-01

Extremes weather changes surpassing their usual statistical ranges and tumbling records in India could be an early warning bell of global warming. Extreme weather events like the recent record setting in western Indian city of Mumbai or all time high fatalities due to the heat wave in southern Indian states or increasing vulnerability of easten Indian states to flood could all be a manifestation of climate change in the Asian subcontinent. While the skeptics may be inclined to dismiss these events as simple local aberrations, when viewed in an epidemiological paradigm in terms of person, time and space couple with frequency, intensity and fatalities, it could well be an early manifestation of climate change. Global warming poses serious challenge to the health sector and hence warrants emergency health preparedness and response. Climate-sensitive diseases are among the largest global killers, hence major brunt of global climate change in terms of adverse health impact will be mostly borne by poor and developing countries in Asia, given the levels of poverty, nutional levels and poor public health infrastructure.

Molecular Characterization and Meta-Analysis of Gut Microbial Communities Illustrate Enrichment of Prevotella and Megasphaera in Indian Subjects.

PubMed

Bhute, Shrikant; Pande, Pranav; Shetty, Sudarshan A; Shelar, Rahul; Mane, Sachin; Kumbhare, Shreyas V; Gawali, Ashwini; Makhani, Hemal; Navandar, Mohit; Dhotre, Dhiraj; Lubree, Himangi; Agarwal, Dhiraj; Patil, Rutuja; Ozarkar, Shantanu; Ghaskadbi, Saroj; Yajnik, Chittaranjan; Juvekar, Sanjay; Makharia, Govind K; Shouche, Yogesh S

2016-01-01

The gut microbiome has varied impact on the wellbeing of humans. It is influenced by different factors such as age, dietary habits, socio-economic status, geographic location, and genetic makeup of individuals. For devising microbiome-based therapies, it is crucial to identify population specific features of the gut microbiome. Indian population is one of the most ethnically, culturally, and geographically diverse, but the gut microbiome features remain largely unknown. The present study describes gut microbial communities of healthy Indian subjects and compares it with the microbiota from other populations. Based on large differences in alpha diversity indices, abundance of 11 bacterial phyla and individual specific OTUs, we report inter-individual variations in gut microbial communities of these subjects. While the gut microbiome of Indians is different from that of Americans, it shared high similarity to individuals from the Indian subcontinent i.e., Bangladeshi. Distinctive feature of Indian gut microbiota is the predominance of genus Prevotella and Megasphaera. Further, when compared with other non-human primates, it appears that Indians share more OTUs with omnivorous mammals. Our metagenomic imputation indicates higher potential for glycan biosynthesis and xenobiotic metabolism in these subjects. Our study indicates urgent need of identification of population specific microbiome biomarkers of Indian subpopulations to have more holistic view of the Indian gut microbiome and its health implications.

Lifestyle Choices Fuel Epidemics of Diabetes and Cardiovascular Disease Among Asian Indians.

PubMed

O'Keefe, Evan L; DiNicolantonio, James J; Patil, Harshal; Helzberg, John H; Lavie, Carl J

2016-01-01

Within the next 15years, India is projected to overtake China as the world's most populous nation. Due to the rapid pace of urbanization and modernization fueling population growth, in conjunction with a genetic predisposition to insulin resistance, India is suffering a rising epidemic of non-communicable diseases (NCDs), including coronary artery disease (CAD), type 2 diabetes mellitus (T2DM), and stroke. In addition to the genetic predisposition, major negative lifestyle factors are contributing to the alarming outbreak of cardiovascular disease (CVD) among the Asian Indian population; these factors include: 1) a diet high in added sugar, refined grains and other processed foods, 2) physical inactivity, 3) vitamin D deficiency (VDD), and 4) smoking/pollution. These risk factors are all highly modifiable, and steps to improve these issues should be taken urgently to avoid a worsening NCD crisis among the inhabitants of the South Asian subcontinent as well as for people with Asian Indian ethnicity worldwide. Copyright © 2015 Elsevier Inc. All rights reserved.

Role of Oceanic and Terrestrial Atmospheric Moisture Sources in Intraseasonal Variability of Indian Summer Monsoon Rainfall.

PubMed

Pathak, Amey; Ghosh, Subimal; Kumar, Praveen; Murtugudde, Raghu

2017-10-06

Summer Monsoon Rainfall over the Indian subcontinent displays a prominent variability at intraseasonal timescales with 10-60 day periods of high and low rainfall, known as active and break periods, respectively. Here, we study moisture transport from the oceanic and terrestrial sources to the Indian landmass at intraseasonal timescales using a dynamic recycling model, based on a Lagrangian trajectory approach applied to the ECMWF-ERA-interim reanalysis data. Intraseasonal variation of monsoon rainfall is associated with both a north-south pattern from the Indian landmass to the Indian Ocean and an east-west pattern from the Core Monsoon Zone (CMZ) to eastern India. We find that the oceanic sources of moisture, namely western and central Indian Oceans (WIO and CIO) contribute to the former, while the major terrestrial source, Ganga basin (GB) contributes to the latter. The formation of the monsoon trough over Indo-Gangetic plain during the active periods results in a high moisture transport from the Bay of Bengal and GB into the CMZ in addition to the existing southwesterly jet from WIO and CIO. Our results indicate the need for the correct representation of both oceanic and terrestrial sources of moisture in models for simulating the intraseasonal variability of the monsoon.

Impact of comprehensive cardiovascular risk reduction programme on risk factor clustering associated with elevated blood pressure in an Indian industrial population.

PubMed

Jeemon, Panniyammakal; Prabhakaran, Dorairaj; Goenka, Shifalika; Ramakrishnan, Lakshmy; Padmanabhan, Sandosh; Huffman, Mark; Joshi, Prashant; Sivasankaran, Sivasubramonian; Mohan, B V M; Ahmed, F; Ramanathan, Meera; Ahuja, R; Sinha, Nakul; Thankappan, K R; Reddy, K S

2012-04-01

Cardiovascular risk factors clustering associated with blood pressure (BP) has not been studied in the Indian population. This study was aimed at assessing the clustering effect of cardiovascular risk factors with suboptimal BP in Indian population as also the impact of risk reduction interventions. Data from 10543 individuals collected in a nation-wide surveillance programme in India were analysed. The burden of risk factors clustering with blood pressure and coronary heart disease (CHD) was assessed. The impact of a risk reduction programmme on risk factors clustering was prospectively studied in a sub-group. Mean age of participants was 40.9 ± 11.0 yr. A significant linear increase in number of risk factors with increasing blood pressure, irrespective of stratifying using different risk factor thresholds was observed. While hypertension occurred in isolation in 2.6 per cent of the total population, co-existence of hypertension and >3 risk factors was observed in 12.3 per cent population. A comprehensive risk reduction programme significantly reduced the mean number of additional risk factors in the intervention population across the blood pressure groups, while it continued to be high in the control arm without interventions (both within group and between group P<0.001). The proportion of 'low risk phenotype' increased from 13.4 to 19.9 per cent in the intervention population and it was decreased from 27.8 to 10.6 per cent in the control population (P<0.001). The proportion of individuals with hypertension and three more risk factors decreased from 10.6 to 4.7 per cent in the intervention arm while it was increased from 13.3 to 17.8 per cent in the control arm (P<0.001). Our findings showed that cardiovascular risk factors clustered together with elevated blood pressure and a risk reduction programme significantly reduced the risk factors burden.

Month-to-month variability of Indian summer monsoon rainfall in 2016: role of the Indo-Pacific climatic conditions

NASA Astrophysics Data System (ADS)

Chowdary, Jasti S.; Srinivas, G.; Du, Yan; Gopinath, K.; Gnanaseelan, C.; Parekh, Anant; Singh, Prem

2018-03-01

Indian summer monsoon (ISM) rainfall during 2016 exhibited a prominent month-to-month fluctuations over India, with below normal rainfall in June and August and above normal rainfall in July. The factors determining the month-to-month fluctuations in ISM rainfall during 2016 are investigated with main focus on the Indo-Pacific climatic anomalies. Warm sea surface temperature (SST) anomalies associated with super El Niño 2015 disappeared by early summer 2016 over the central and eastern Pacific. On the other hand, negative Indian Ocean dipole (IOD) like SST anomaly pattern over the equatorial Indian Ocean and anomalous anticyclonic circulation over the western North Pacific (WNP) are reported in summer 2016 concurrently with decaying El Niño/developing La Niña phase. Observations revealed that the low rainfall over central north India in June is due to moisture divergence caused by the westward extension of ridge corresponding to WNP anticyclone and subsidence induced by local Hadley cell partly related to negative IOD. Low level convergence of southeasterly wind from Bay of Bengal associated with weak WNP anticyclone and northwesterly wind corresponding to anticyclonic circulation over the northwest India remarkably contributed to positive rainfall in July over most of the Indian subcontinent. While reduced rainfall over the Indian subcontinent in August 2016 is associated with the anomalous moisture transport from ISM region to WNP region, in contrast to July, due to local cyclogenesis corroborated by number of tropical cyclones in the WNP. In addition to this, subsidence related to strong convection supported by cyclonic circulation over the WNP also resulted in low rainfall over the ISM region. Coupled General Circulation model sensitivity experiments confirmed that strong convective activities associated with cyclonic circulation over the WNP is primarily responsible for the observed negative ISM rainfall anomalies in August 2016. It is noted that the Indo

Genetic Evidence on the Origins of Indian Caste Populations

PubMed Central

Bamshad, Michael; Kivisild, Toomas; Watkins, W. Scott; Dixon, Mary E.; Ricker, Chris E.; Rao, Baskara B.; Naidu, J. Mastan; Prasad, B.V. Ravi; Reddy, P. Govinda; Rasanayagam, Arani; Papiha, Surinder S.; Villems, Richard; Redd, Alan J.; Hammer, Michael F.; Nguyen, Son V.; Carroll, Marion L.; Batzer, Mark A.; Jorde, Lynn B.

2001-01-01

The origins and affinities of the ∼1 billion people living on the subcontinent of India have long been contested. This is owing, in part, to the many different waves of immigrants that have influenced the genetic structure of India. In the most recent of these waves, Indo-European-speaking people from West Eurasia entered India from the Northwest and diffused throughout the subcontinent. They purportedly admixed with or displaced indigenous Dravidic-speaking populations. Subsequently they may have established the Hindu caste system and placed themselves primarily in castes of higher rank. To explore the impact of West Eurasians on contemporary Indian caste populations, we compared mtDNA (400 bp of hypervariable region 1 and 14 restriction site polymorphisms) and Y-chromosome (20 biallelic polymorphisms and 5 short tandem repeats) variation in ∼265 males from eight castes of different rank to ∼750 Africans, Asians, Europeans, and other Indians. For maternally inherited mtDNA, each caste is most similar to Asians. However, 20%–30% of Indian mtDNA haplotypes belong to West Eurasian haplogroups, and the frequency of these haplotypes is proportional to caste rank, the highest frequency of West Eurasian haplotypes being found in the upper castes. In contrast, for paternally inherited Y-chromosome variation each caste is more similar to Europeans than to Asians. Moreover, the affinity to Europeans is proportionate to caste rank, the upper castes being most similar to Europeans, particularly East Europeans. These findings are consistent with greater West Eurasian male admixture with castes of higher rank. Nevertheless, the mitochondrial genome and the Y chromosome each represents only a single haploid locus and is more susceptible to large stochastic variation, bottlenecks, and selective sweeps. Thus, to increase the power of our analysis, we assayed 40 independent, biparentally inherited autosomal loci (1 LINE-1 and 39 Alu elements) in all of the caste and

Desert Dust and Monsoon Rain

NASA Technical Reports Server (NTRS)

Lau, William K. M.; Kim, Kyu-Myong

2014-01-01

For centuries, inhabitants of the Indian subcontinent have know that heavy dust events brought on by strong winds occur frequently in the pre-monsoon season, before the onset of heavy rain. Yet scientists have never seriously considered the possibility that natural dust can affect monsoon rainfall. Up to now, most studies of the impacts of aerosols on Indian monsoon rainfall have focused on anthropogenic aerosols in the context of climate change. However, a few recent studies have show that aerosols from antropogenic and natural sources over the Indian subcontinent may affect the transition from break to active monsoon phases on short timescales of days to weeks. Writing in Nature Geoscience, Vinoj and colleagues describe how they have shown that desert dust aerosols over the Arabian Sea and West Asia can strenghten the summer monsoon over the Indial subcontinent in a matter of days.

Fat distribution and insulin resistance in young adult nonobese Asian Indian women.

PubMed

Szuszkiewicz-Garcia, Magdalene; Li, Rong; Grundy, Scott M; Abate, Nicola; Chandalia, Manisha

2012-10-01

Although Asian Indian (people of Indian subcontinent descent) men are shown to have higher total and truncal body fat as well as greater insulin resistance compared to white men matched for total body fat and age, data in women are not conclusive. The objective of this study was to compare total and regional fat distribution and insulin sensitivity between healthy young premenopausal Asian Indian and white women of similar body mass index (BMI). Twenty Asian Indian women (65% immigrants and 35% first generation living in Dallas) and 31 white women of similar age and BMI [age 24±3 vs. 25±4; BMI 22±4 vs. 23±5; mean±standard deviation (SD) in Asian Indian and white, respectively] without diabetes were evaluated with anthropometric measurements, underwater weighing for percentage of total body fat mass, magnetic resonance imaging of whole abdomen for measurement of abdominal subcutaneous and intraperitoneal fat mass, and euglycemic-hyperinsulinemic clamp study for measurement of insulin sensitivity. There were no differences in waist or hip circumference, total body subcutaneous abdominal or intraperitoneal fat mass, fasting plasma glucose, and insulin levels between Asian Indian women and white women. The peripheral glucose disposal rate (Rd) during hyperinsulinemic-euglycemic clamp was found to be almost identical in the two study groups (median value of 6.9 and 6.8 mg/min per kg of body weight, for Asian Indians and whites, respectively). For similar total or regional fat content, the glucose disposal rate was comparable in the two study groups. In conclusion, we demonstrate that young Asian Indian women do not have excess abdominal or intraperitoneal fat or insulin resistance for similar BMI compared to white women of European descent.

Fat Distribution and Insulin Resistance in Young Adult Nonobese Asian Indian Women

PubMed Central

Szuszkiewicz-Garcia, Magdalene; Li, Rong; Grundy, Scott M.; Abate, Nicola

2012-01-01

Abstract Although Asian Indian (people of Indian subcontinent descent) men are shown to have higher total and truncal body fat as well as greater insulin resistance compared to white men matched for total body fat and age, data in women are not conclusive. The objective of this study was to compare total and regional fat distribution and insulin sensitivity between healthy young premenopausal Asian Indian and white women of similar body mass index (BMI). Twenty Asian Indian women (65% immigrants and 35% first generation living in Dallas) and 31 white women of similar age and BMI [age 24±3 vs. 25±4; BMI 22±4 vs. 23±5; mean±standard deviation (SD) in Asian Indian and white, respectively] without diabetes were evaluated with anthropometric measurements, underwater weighing for percentage of total body fat mass, magnetic resonance imaging of whole abdomen for measurement of abdominal subcutaneous and intraperitoneal fat mass, and euglycemic–hyperinsulinemic clamp study for measurement of insulin sensitivity. There were no differences in waist or hip circumference, total body subcutaneous abdominal or intraperitoneal fat mass, fasting plasma glucose, and insulin levels between Asian Indian women and white women. The peripheral glucose disposal rate (Rd) during hyperinsulinemic–euglycemic clamp was found to be almost identical in the two study groups (median value of 6.9 and 6.8 mg/min per kg of body weight, for Asian Indians and whites, respectively). For similar total or regional fat content, the glucose disposal rate was comparable in the two study groups. In conclusion, we demonstrate that young Asian Indian women do not have excess abdominal or intraperitoneal fat or insulin resistance for similar BMI compared to white women of European descent. PMID:22746275

Pattern of Glacier Recession in Indian Himalaya

NASA Astrophysics Data System (ADS)

Singh, Ajay; Patwardhan, Anand

All currently available climate models predict a near-surface warming trend under the influence of rising levels of greenhouse gases in the atmosphere. In addition to the direct effects on climate — for example, on the frequency of heat waves — this increase in surface temperatures has important consequences for the cryosphere subsequently hydrological cycle, particularly in regions where water supply is currently dominated by melting snow or ice. The Indian Himalayan region occupies a special place in the mountain ecosystems of the world. These geodynamically young mountains are not only important from the standpoint of climate and as a provider of life, giving water to a large part of the Indian subcontinent, but they also harbor a rich variety of flora, fauna, human communities and cultural diversity. Glaciers in this region are changing in area as well as in volume like those in other parts of the world. Studies have been carried out for recession in some of these glaciers using remote sensing as well as field observation techniques. Spatiotemporal pattern in the recession rate of the studied glaciers has been presented in this paper. Plausible causes for the recession have been also discussed. Finally, future scopes for observation and analysis in glaciers recession have been suggested.

The Case for High Resolution Extended 6-Loci HLA Typing for Identifying Related Donors in the Indian Subcontinent.

PubMed

Agarwal, Rajat Kumar; Kumari, Ankita; Sedai, Amit; Parmar, Lalith; Dhanya, Rakesh; Faulkner, Lawrence

2017-09-01

%) consanguinity was unknown. We identified 18 donors (6%; 13 siblings and 5 parents) who would have been considered a 12/12 match by LR HLA typing alone but were found not to match on extended HR typing. In this group, 11 donors (61%) were from consanguineous families, 3 donors (17%) had no reported consanguinity, and in 4 donors (22%) consanguinity was unknown. Outcome analysis showed that the actuarial proportion of patients with GVHD was 4% in the FT group compared with 16% in the ST group, with log-rank P = .1952. The ST group included 2 patients with grade III-IV acute GVHD and 1 patient each with moderate and severe chronic GVHD, whereas the FT group only 1 patient with grade III acute GVHD. We conclude that even in the context of related donors, the use of LR and/or 3-loci (A, B, and DRB1) HR HLA typing might result in a sizable risk of missing a clinically relevant mismatch, which may have an adverse impact on transplantation outcomes. In the Indian subcontinent, this observation is not limited to putatively compatible parents or consanguineous families; we recommend full 6-loci HR HLA typing even for matched related BMTs. Copyright © 2017 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

Mitochondrial DNA analyses revealed low genetic diversity in the endangered Indian wild ass Equus hemionus khur.

PubMed

Khaire, Devendra; Atkulwar, Ashwin; Farah, Sameera; Baig, Mumtaz

2017-09-01

The Indian wild ass Equus hemionus khur, belonging to ass-like equid branch, inhabits the dry and arid desert of the Little Rann of Kutch, Gujarat. The E. h. khur is the sole survivor of Asiatic wild ass species/subspecies in South Asia. To provide first ever insights into the genetic diversity, phylogeny, and demography of the endangered Indian wild ass, we sampled 52 free-ranging individuals from the Little Rann of Kutch by using a non-invasive methodology. The sequencing of 230 bp in cytochrome b (Cyt b) and displacement loop (D-loop) region revealed that current ∼4000 extant population of Indian wild ass harbours low genetic diversity. Phylogenetic analyses confirmed that E. h. khur, E. h. onager, and E. h. kulan belong to a single strict monophyletic clade. Therefore, we suggest the delimitation of the five E. hemionus subspecies in vogue to a single species E. hemionus. The application of molecular clock confirmed that the Asiatic wild ass had undergone diversification 0.65 Million years ago. Demographic measurements assessed using a Bayesian skyline plot demonstrated decline in the maternal effective population size of the Indian wild ass during different periods; these periods coincided with the origin and rise of the Indus civilization in the northwest of the Indian subcontinent during the Neolithic. In conclusion, maintaining high genetic diversity in the existing isolated population of 4000 Indian wild asses inhabiting the wild ass sanctuary is important compared with subspecies preservation alone.

Description of a New Quadrigyrid Acanthocephalan from Kashmir, with Notes on Metal Analysis and Histopathology, and a Key to Species of the Subgenus Acanthosentis from the Indian Subcontinent.

PubMed

Amin, Omar M; Heckmann, Richard A; Zargar, Ummer Rashid

2017-10-01

Acanthogyrus (Acanthosentis) kashmirensis n. sp. is described from recently collected acanthocephalan specimens in the Jhelum River in northern Kashmir that are conspecific with Neoechinorhynchus kashmirensis Fotedar and Dhar, 1977 originally described in a Ph.D. thesis in 1972 from 4 species of cyprinid fishes: Tor tor Hamilton, Bangana diplostoma (Heckel) (syn. Labeo diplostoma Heckel), Labeo rohita Hamilton, and Ptychobarbus sp. Steindachner. The poor unpublished diagnosis was followed by 1 uninformative abstract in a scientific meeting in 1977. The acanthocephalan was later designated as invalid because of the lack of a formal published description and absence of information on deposited type or voucher specimens. Recent collections of specimens of the same species were made from 2 other cyprinid species of cyprinid fishes, Schizothorax plagiostomus Heckel and Schizothorax labiatus (McClelland) from the Sandran River, a tributary of the Jhelum River, in southern Kashmir. It is now possible to provide a full description of these specimens and reassign them in the subgenus Acanthosentis Verma and Datta, 1929 based on the finding of circles of vestigial spines at the anterior end of the trunk of male and female specimens. These vestigial spines are barely visible and easy to miss with optical microscopy. The new species is also characterized by having (1) a para-receptacle structure in males and females, (2) unique double Saefftigen's pouches, (3) large round single-nucleated cells in the proboscis, and (4) the lemnisci being either equal or distinctly unequal with no intermediate states. A key to the species of Acanthosentis of the Indian subcontinent is provided. Histopathological sections show extensive damage to the host intestine with subsequent blood loss, cell necrosis, and attempted encapsulation. Results of the energy dispersive X-ray analysis (EDAX) study show hollow hooks high in sulfur but with limited calcium ions. Hooks of most acanthocephalans

Regime shift of Indian summer monsoon rainfall to a persistent arid state: external forcing versus internal variability

NASA Astrophysics Data System (ADS)

Srivastava, Ankur; Pradhan, Maheswar; Goswami, B. N.; Rao, Suryachandra A.

2017-11-01

The high propensity of deficient monsoon rainfall over the Indian sub-continent in the recent 3 decades (seven deficient monsoons against 3 excess monsoon years) compared to the prior 3 decades has serious implications on the food and water resources in the country. Motivated by the need to understand the high occurrence of deficient monsoon during this period, we examine the change in predictability of the Indian summer monsoon (ISM) and its teleconnections with Indo-Pacific sea surface temperatures between the two periods. The shift in the tropical climate in the late 1970s appears to be one of the major reasons behind this. We find an increased predictability of the ISM in the recent 3 decades owing to reduced `internal' interannual variability (IAV) due to the high-frequency modes, while the `external' IAV arising from the low-frequency modes has remained largely the same. The Indian Ocean Dipole-ISM teleconnection has become positive during the monsoon season in the recent period thereby compensating for the weakened ENSO-ISM teleconnection. The central Pacific El-Niño and the Indian Ocean (IO) warming during the recent 3 decades are working together to realise enhanced ascending motion in the equatorial IO between 70°E and 100°E, preconditioning the Indian monsoon system prone to a deficient state.

Imaging Lithospheric Structure beneath the Indian continent

NASA Astrophysics Data System (ADS)

Maurya, S.; Montagner, J. P.; Mangalampally, R. K.; Stutzmann, E.; Burgos, G.; Kumar, P.; Davuluri, S.

2015-12-01

The lithospheric structure and thickness to the LAB are the most debated issues, especially beneath continents. In this context, the structure and thickness of the Indian lithosphere has been controversial. Paleomagnetic data reveals that the Indian continent moved northwards at exceptionally high speeds (18-20 cm/year) and subsequently slowed down to 4-5 cm/year after its collision with Asia ≈40 Myr ago. This super mobility has been explained by an unusually thin Indian lithosphere (≈100 km; Kumar et al., 2007) in contradiction with the thick lithosphere that commonly underlies old cratonic nuclei. It is pertinent to note that the thermobarometric estimates on the ultramafic xenoliths from 65 Myr kimberlites of the Central India (Babu et al. 2009) suggest an approximately 175 km thick lithosphere. Also, recent results of P and S wave travel time tomography of India suggest that the lithospheric roots are not uniformly thick on a regional scale. Although high velocity roots typical of Precambrian shields are preserved beneath a few cratons of the Indian shield, they seem to have suffered attrition, in the plume ravaged regions like the NDVP and the Southern SGT (Singh et al., 2014). We assembled a new massive surface wave database towards obtaining 3D isotropic and anisotropic models for the Indian sub-continent, using surface waves. This necessitated processing of data from more than 500 seismic broadband stations across India and surrounding regions. Surface waves group and phase dispersion measurements are performed in a broad frequency range (16-250s). Our phase velocity anomaly maps recover most of the known geological structures. The cratons are associated with high velocity (4-6%) anomalies till 200 sec, with the WDC being faster than the EDC. Slow velocities in NW India and very high velocity anomalies (6-8%) beneath the central part of the Indo-Gangetic plains are possibly associated with the subducting Indian lithosphere. The LAB depths inferred from

Restricted genetic variation in populations of Achatina (Lissachatina) fulica outside of East Africa and the Indian Ocean Islands points to the Indian Ocean Islands as the earliest known common source.

PubMed

Fontanilla, Ian Kendrich C; Sta Maria, Inna Mikaella P; Garcia, James Rainier M; Ghate, Hemant; Naggs, Fred; Wade, Christopher M

2014-01-01

The Giant African Land Snail, Achatina ( =  Lissachatina) fulica Bowdich, 1822, is a tropical crop pest species with a widespread distribution across East Africa, the Indian subcontinent, Southeast Asia, the Pacific, the Caribbean, and North and South America. Its current distribution is attributed primarily to the introduction of the snail to new areas by Man within the last 200 years. This study determined the extent of genetic diversity in global A. fulica populations using the mitochondrial 16S ribosomal RNA gene. A total of 560 individuals were evaluated from 39 global populations obtained from 26 territories. Results reveal 18 distinct A. fulica haplotypes; 14 are found in East Africa and the Indian Ocean islands, but only two haplotypes from the Indian Ocean islands emerged from this region, the C haplotype, now distributed across the tropics, and the D haplotype in Ecuador and Bolivia. Haplotype E from the Philippines, F from New Caledonia and Barbados, O from India and Q from Ecuador are variants of the emergent C haplotype. For the non-native populations, the lack of genetic variation points to founder effects due to the lack of multiple introductions from the native range. Our current data could only point with certainty to the Indian Ocean islands as the earliest known common source of A. fulica across the globe, which necessitates further sampling in East Africa to determine the source populations of the emergent haplotypes.

Restricted Genetic Variation in Populations of Achatina (Lissachatina) fulica outside of East Africa and the Indian Ocean Islands Points to the Indian Ocean Islands as the Earliest Known Common Source

PubMed Central

Fontanilla, Ian Kendrich C.; Sta. Maria, Inna Mikaella P.; Garcia, James Rainier M.; Ghate, Hemant; Naggs, Fred; Wade, Christopher M.

2014-01-01

The Giant African Land Snail, Achatina ( = Lissachatina) fulica Bowdich, 1822, is a tropical crop pest species with a widespread distribution across East Africa, the Indian subcontinent, Southeast Asia, the Pacific, the Caribbean, and North and South America. Its current distribution is attributed primarily to the introduction of the snail to new areas by Man within the last 200 years. This study determined the extent of genetic diversity in global A. fulica populations using the mitochondrial 16S ribosomal RNA gene. A total of 560 individuals were evaluated from 39 global populations obtained from 26 territories. Results reveal 18 distinct A. fulica haplotypes; 14 are found in East Africa and the Indian Ocean islands, but only two haplotypes from the Indian Ocean islands emerged from this region, the C haplotype, now distributed across the tropics, and the D haplotype in Ecuador and Bolivia. Haplotype E from the Philippines, F from New Caledonia and Barbados, O from India and Q from Ecuador are variants of the emergent C haplotype. For the non-native populations, the lack of genetic variation points to founder effects due to the lack of multiple introductions from the native range. Our current data could only point with certainty to the Indian Ocean islands as the earliest known common source of A. fulica across the globe, which necessitates further sampling in East Africa to determine the source populations of the emergent haplotypes. PMID:25203830

Assessing the impact of the Indian Ocean tsunami on households: a modified domestic assets index approach.

PubMed

Arlikatti, Sudha; Peacock, Walter Gillis; Prater, Carla S; Grover, Himanshu; Sekar, Arul S Gnana

2010-07-01

This paper offers a potential measurement solution for assessing disaster impacts and subsequent recovery at the household level by using a modified domestic assets index (MDAI) approach. Assessment of the utility of the domestic assets index first proposed by Bates, Killian and Peacock (1984) has been confined to earthquake areas in the Americas and southern Europe. This paper modifies and extends the approach to the Indian sub-continent and to coastal surge hazards utilizing data collected from 1,000 households impacted by the Indian Ocean tsunami (2004) in the Nagapattinam district of south-eastern India. The analyses suggest that the MDAI scale is a reliable and valid measure of household living conditions and is useful in assessing disaster impacts and tracking recovery efforts over time. It can facilitate longitudinal studies, encourage cross-cultural, cross-national comparisons of disaster impacts and inform national and international donors of the itemized monetary losses from disasters at the household level.

Genetic Evidence for Recent Population Mixture in India

PubMed Central

Moorjani, Priya; Thangaraj, Kumarasamy; Patterson, Nick; Lipson, Mark; Loh, Po-Ru; Govindaraj, Periyasamy; Berger, Bonnie; Reich, David; Singh, Lalji

2013-01-01

Most Indian groups descend from a mixture of two genetically divergent populations: Ancestral North Indians (ANI) related to Central Asians, Middle Easterners, Caucasians, and Europeans; and Ancestral South Indians (ASI) not closely related to groups outside the subcontinent. The date of mixture is unknown but has implications for understanding Indian history. We report genome-wide data from 73 groups from the Indian subcontinent and analyze linkage disequilibrium to estimate ANI-ASI mixture dates ranging from about 1,900 to 4,200 years ago. In a subset of groups, 100% of the mixture is consistent with having occurred during this period. These results show that India experienced a demographic transformation several thousand years ago, from a region in which major population mixture was common to one in which mixture even between closely related groups became rare because of a shift to endogamy. PMID:23932107

Ferritin as a Risk Factor for Glucose Intolerance amongst Men and Women Originating from the Indian Subcontinent.

PubMed

Hughes, Elizabeth A; Patel, Jeetesh V; Bredow, Zosia; Gill, Paramjit S; Chackathayil, Julia; Agaoglu, Elif S; Flinders, Paul; Mirrielees, Rebecca

2015-01-01

Background. Serum ferritin predicts the onset of diabetes; however, this relationship is not clear amongst South Asians, a population susceptible to glucose intolerance and anaemia. Objective. This study tests whether ferritin levels reflect glucose tolerance in South Asians, independent of lifestyle exposures associated with Indian or British residence. Methods. We randomly sampled 227 Gujaratis in Britain (49.8 (14.4) years, 50% men) and 277 contemporaries living in Gujarati villages (47.6 (11.8) years, 41% men). Both groups underwent a 75 g oral-glucose-tolerance test. We evaluated lifestyle parameters with standardised questionnaires and conducted comprehensive clinical and lab measurements. Results. Across sites, the age-adjusted prevalence of diabetes was 9.8%. Serum ferritin was higher amongst diabetics (P = 0.005), irrespective of site, gender, and central obesity (P ≤ 0.02), and was associated with fasting and postchallenge glucose, anthropometry, blood pressure, triglycerides, and nonesterified fatty acids (P < 0.001). Diabetes was less in those with low ferritin (<20 mg/mL), P < 0.008, and risk estimate = 0.35 (95% CI 0.15-0.81), as were blood pressure and metabolic risk factors. On multivariate analysis, diabetes was independently associated with ferritin (P = 0.001) and age (P < 0.001). Conclusion. Ferritin levels are positively associated with glucose intolerance in our test groups, independent of gender and Indian or UK lifestyle factors.

Mitochondrial population genomic analyses reveal population structure and demography of Indian Plasmodium falciparum.

PubMed

Tyagi, Suchi; Das, Aparup

2015-09-01

Inference on the genetic diversity of Plasmodium falciparum populations could help in better management of malaria. A very recent study with mitochondrial (mt) genomes in global P. falciparum had revealed interesting evolutionary genetic patterns of Indian isolates in comparison to global ones. However, no population genetic study using the whole mt genome sequences of P. falciparum isolates collected in the entire distribution range in India has yet been performed. We herewith have analyzed 85 whole mt genomes (48 already published and 37 entirely new) sampled from eight differentially endemic Indian locations to estimate genetic diversity and infer population structure and historical demography of Indian P. falciparum. We found 19 novel Indian-specific Single Nucleotide Polymorphisms (SNPs) and 22 novel haplotypes segregating in Indian P. falciparum. Accordingly, high haplotype and nucleotide diversities were detected in Indian P. falciparum in comparison to many other global isolates. Indian P. falciparum populations were found to be moderately sub-structured with four different genetic clusters. Interestingly, group of local populations aggregate to form each cluster; while samples from Jharkhand and Odisha formed a single cluster, P. falciparum isolates from Asom formed an independent one. Similarly, Surat, Bilaspur and Betul formed a single cluster and Goa and Mangalore formed another. Interestingly, P. falciparum isolates from the two later populations were significantly genetically differentiated from isolates collected in other six Indian locations. Signature of historical population expansion was evident in five population samples, and the onset of expansion event was found to be very similar to African P. falciparum. In agreement with the previous finding, the estimated Time to Most Recent Common Ancestor (TMRCA) and the effective population size were high in Indian P. falciparum. All these genetic features of Indian P. falciparum with high mt genome

When Indian crabs were not yet Asian - biogeographic evidence for Eocene proximity of India and Southeast Asia

PubMed Central

2010-01-01

Background The faunal and floral relationship of northward-drifting India with its neighboring continents is of general biogeographic interest as an important driver of regional biodiversity. However, direct biogeographic connectivity of India and Southeast Asia during the Cenozoic remains largely unexplored. We investigate timing, direction and mechanisms of faunal exchange between India and Southeast Asia, based on a molecular phylogeny, molecular clock-derived time estimates and biogeographic reconstructions of the Asian freshwater crab family Gecarcinucidae. Results Although the Gecarcinucidae are not an element of an ancient Gondwana fauna, their subfamily Gecarcinucinae, and probably also the Liotelphusinae, evolved on the Indian Subcontinent and subsequently dispersed to Southeast Asia. Estimated by a model testing approach, this dispersal event took place during the Middle Eocene, and thus before the final collision of India and the Tibet-part of Eurasia. Conclusions We postulate that the India and Southeast Asia were close enough for exchange of freshwater organisms during the Middle Eocene, before the final Indian-Eurasian collision. Our data support geological models that assume the Indian plate having tracked along Southeast Asia during its move northwards. PMID:20849594

Vegetarian diet as a risk factor for tuberculosis in immigrant south London Asians.

PubMed Central

Strachan, D. P.; Powell, K. J.; Thaker, A.; Millard, F. J.; Maxwell, J. D.

1995-01-01

BACKGROUND--In a previous retrospective study of tuberculosis in south London among Asian immigrants from the Indian subcontinent Hindu Asians were found to have a significantly increased risk for tuberculosis compared with Muslims. This finding has been further investigated by examining the role of socioeconomic and lifestyle variables, including diet, as risk factors for tuberculosis in Asian immigrants from the Indian subcontinent resident in south London. METHODS--Using a case-control study technique Asian immigrants from the Indian subcontinent diagnosed with tuberculosis during the past 10 years and two Asian control groups (community and outpatient clinic controls) from the Indian subcontinent were investigated. Cases and community controls were approached by letter. A structured questionnaire concerning a range of demographic, migration, socioeconomic, dietary, and health topics was administered by a single trained interviewer to subjects (56 cases and 100 controls) who agreed to participate. RESULTS--The results confirmed earlier findings that Hindu Asians had an increased risk of tuberculosis compared with Muslims. However, further analysis revealed that religion had no independent influence after adjustment for vegetarianism (common among Hindu Asians). Unadjusted odds ratios for tuberculosis among vegetarians were 2.7 (95% CI 1.1 to 6.4) using community controls, and 4.3 (95% CI 1.8 to 10.4) using clinic controls. There was a trend of increasing risk of tuberculosis with decreasing frequency of meat or fish consumption. Lactovegetarians had an 8.5 fold risk (95% CI 1.6 to 45.4) compared with daily meat/fish eaters. Adjustment for a range of other socioeconomic, migration, and lifestyle variables made little difference to the relative risks derived using either community or clinic controls. CONCLUSIONS--These results indicate that a vegetarian diet is an independent risk factor for tuberculosis in immigrant Asians. The mechanism is unexplained. However

Diversity and divergence among the tribal populations of India.

PubMed

Watkins, W S; Prasad, B V R; Naidu, J M; Rao, B B; Bhanu, B A; Ramachandran, B; Das, P K; Gai, P B; Reddy, P C; Reddy, P G; Sethuraman, M; Bamshad, M J; Jorde, L B

2005-11-01

Tribal populations of the Indian subcontinent have been of longstanding interest to anthropologists and human geneticists. To investigate the relationship of Indian tribes to Indian castes and continental populations, we analyzed 45 unlinked autosomal STR loci in 9 tribal groups, 8 castes, and 18 populations from Africa, Europe and East Asia. South Indian tribal populations demonstrate low within-population heterozygosity (range: 0.54 - 0.69), while tribal populations sampled further north and east have higher heterozygosity (range: 0.69 - 0.74). Genetic distance estimates show that tribal Indians are more closely related to caste Indians than to other major groups. Between-tribe differentiation is high and exceeds that for eight sub-Saharan African populations (4.8% vs. 3.7%). Telugu-speaking populations are less differentiated than non-Telugu speakers (F(ST): 0.029 vs. 0.079), but geographic distance was not predictive of genetic affinity between tribes. South Indian tribes show significant population structure, and individuals can be clustered statistically into groups that correspond with their tribal affiliation. These results are consistent with high levels of genetic drift and isolation in Indian tribal populations, particularly those of South India, and they imply that these populations may be potential candidates for linkage disequilibrium and association mapping.

Intraseasonal SST-precipitation coupling during the Indian Summer Monsoon, and its modulation by the Indian Ocean Dipole

NASA Astrophysics Data System (ADS)

Jongaramrungruang, S.; Seo, H.; Ummenhofer, C.

2016-02-01

The Indian Summer Monsoon (ISM) plays a crucial role in shaping the large proportion of the total precipitation over the Indian subcontinent each year. The ISM rainfall exhibits a particularly strong intraseasonal variability, that has profound socioeconomic consequences, such as agricultural planning and flood preparation. However, our understanding of the variability on this time scale is still limited due to sparse data availability in the past. In this study, we used a combination of state-of-the-art high-resolution satellite estimate of rainfall, objectively analyzed surface flux, as well as atmospheric reanalysis product to investigate the nature of the ISM intraseasonal rainfall variability and how it varies year to year. The emphasis is placed on the Bay of Bengal (BoB) where the intraseasonal ocean-atmosphere coupling is most prominent. Results show that the maximum warming of SST leads the onset of heavy precipitation event by 3-5 days, and that surface heat flux and surface wind speed are weak prior to the rain but amplifies and peaks after the rain reaches its maximum. Furthermore, the Indian Ocean Dipole (IOD) significantly affects the observed intraseasonal SST-precipitation relationship. The pre-convection SST warming is stronger and more pronounced during the negative phase of the IOD, while the signal is weaker and less organized in the positive phase. This is explained by the column-integrated moisture budget analysis which reveals that, during the ISM heavy rainfall in the BoB, there is more moisture interchange in the form of enhanced vertical advection from the ocean to atmosphere in negative IOD years as compared to positive IOD years. Knowing the distinction of ISM variabilities during opposite phases of the IOD will help contribute to a more reliable prediction of ISM activities.

Trace Gases and Aerosols Simulated Over the Indian Domain: Evaluation of the Model Wrf-Chem

NASA Astrophysics Data System (ADS)

Michael, M.; Yadav, A.; Tripathi, S. N.; Venkataraman, C.; Kanawade, V. P.

2012-12-01

As the anthropogenic emissions from the Asian countries contribute substantially to the global aerosol loading, the study of the distribution of trace gases and aerosols over this region has received increasing attention in recent years. In the present work, the aerosol properties over the Indian domain during the pre-monsoon season has been addressed. The "online" meteorological and chemical transport Weather Research and Forecasting-Chemistry (WRF-Chem) model has been implemented over Indian subcontinent for three consecutive summers in 2008, 2009 and 2010.The initial and boundary conditions are obtained from NCAR reanalysis data. The global emission inventories (REanalysis of the TROpospheric chemical composition (RETRO) and Emissions Database for Global Atmospheric Research (EDGAR)) have been used and are projected for the period of study using the method provided in Ohara et al. (2007). The emission rates of sulfur dioxide, black carbon, organic carbon and PM2.5 available in the global inventory are replaced with the high resolution emission inventory developed over India for the present study. The model simulates meteorological parameters, trace gases and particulate matter. Simulated mixing ratios of trace gases (Ozone, carbon monoxide, nitrogen oxides, and SO2) are compared with ground based as well as satellite observations over India with specific focus on Indo-Gangetic Plain. Simulated aerosol optical depth are in good agreement with those observed by Aerosol Robotic Network (AERONET). The vertical profiles of extinction coefficient have been compared with the Micro Pulse Lidar Network (MPLnet) data. The simulated mass concentration of BC shows very good agreement with those observed at a few ground stations. The vertical profiles of BC have also been compared with aircraft observations carried out during summer of 2008 and 2009, resulting in good agreement. This study shows that WRF-Chem model captures many important features of the observations and

Towards elimination of visceral leishmaniasis in the Indian subcontinent—Translating research to practice to public health

PubMed Central

Kroeger, Axel; Matlashewski, Greg; Mondal, Dinesh; Banjara, Megha Raj; Das, Pradeep; Be-Nazir, Ahmed; Arana, Byron; Olliaro, Piero

2017-01-01

Background The decade following the Regional Strategic Framework for Visceral Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of VL burden in the Indian subcontinent. The Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the World Health Organization (WHO) and other stakeholders, has coordinated and financed research for the development of new innovative tools and strategies to support the regional VL elimination initiative. This paper describes the process of the TDR’s engagement and contribution to this initiative. Methodology/principal findings Multiple databases were searched to identify 152 scientific papers and reports with WHO funding or authorship affiliation around the following 3 framework strategies: detection of new cases, morbidity reduction, and prevention of infection. TDR has played a critical role in the evaluation and subsequent use of the 39-aminoacid–recombinant kinesin antigen (rK39) rapid diagnostic test (RDT) as a confirmatory test for VL in the national program. TDR has supported the clinical research and development of miltefosine and single-dose liposomal amphotericin B as a first-line treatment against VL. TDR has engaged with in-country researchers, national programme managers, and partners to generate evidence-based interventions for early detection and treatment of VL patients. TDR evaluated the quality, community acceptance, and cost effectiveness of indoor residual spraying, insecticide-treated bed nets, insecticide-impregnated durable wall linings, insecticidal paint, and environmental management as tools for integrated vector management in reducing sandfly density. Conclusions/significance TDR’s engagement with country policy makers, scientists, and clinicians in the development of effective diagnosis, treatment, case detection, and vector control represents an important example of TDR’s stewardship toward the elimination of VL in the Indian subcontinent

Evolution of the net surface shortwave radiation over the Indian Ocean during summer MONEX (1979) - A satellite description

NASA Technical Reports Server (NTRS)

Gautier, C.

1986-01-01

The evolution of the net shortwave (NSW) radiation fields during the monsoon of 1979 was analyzed, using geostationary satellite data, collected before, during, and after the monsoon onset. It is seen, from the time sequence of NSW fields, that during the preonset phase the characteristics of the NSW field are dominated by a strong maximum in the entire Arabian Sea and by a strong minimum in the central and eastern equatorial Indian Ocean, the minimum being associated with the intense convective activity occurring in that region. As the season evolves, the minima of NSW associated with the large scale convective activity propagate westward in the equatorial ocean. During the monsoon onset, there occurs an explosive onset of the convection activity in the Arabian Sea: the maximum has retreated towards the Somalia coast, and most of the sea then experiences a strong minimum of NSW associated with the intense precipitation occurring along the southwestern coast of the Indian subcontinent.

Bhasma : The ancient Indian nanomedicine

PubMed Central

Pal, Dilipkumar; Sahu, Chandan Kumar; Haldar, Arindam

2014-01-01

Ayurveda and other Indian system of medicine use metals, but their use is also amply described in Chinese and Egyptian civilization in 2500 B.C. Bhasma are unique ayurvedic metallic/minerals preparation, treated with herbal juice or decoction and exposed for Ayurveda, which are known in Indian subcontinent since 7th century A.D. and widely recommended for treatment of a variety of chronic ailments. Animal's derivative such as horns, shells, feathers, metallic, nonmetallic and herbals are normally administered as Bhasma. A Bhasma means an ash obtained through incineration; the starter material undergoes an elaborate process of purification and this process is followed by the reaction phase, which involves incorporation of some other minerals and/or herbal extract. There are various importance of Bhasma like maintaining optimum alkalinity for optimum health, neutralizing harmful acids that lead to illness; because Bhasma do not get metabolized so they don’t produce any harmful metabolite, rather it breakdowns heavy metals in the body. Methods including for Bhasma preparation are parpati, rasayoga, sindora, etc., Bhasma which contain Fe, Cu, S or other manufacturing process plays a specific role in the final product(s). Particle size (1-2 μ) reduced significantly, which may facilitate absorption and assimilation of the drug into the body system. Standardization of Bhasma is utmost necessary to confirm its identity and to determine its quality, purity safety, effectiveness and acceptability of the product. But the most important challenges faced by these formulations are the lack of complete standardization by physiochemical parameters. PMID:24696811

Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease

PubMed Central

Shanker, Jayashree; Perumal, Ganapathy; Rao, Veena S; Khadrinarasimhiah, Natesha B; John, Shibu; Hebbagodi, Sridhara; Mukherjee, Manjari; Kakkar, Vijay V

2008-01-01

Background The APOA1-C3-A5 gene cluster plays an important role in the regulation of lipids. Asian Indians have an increased tendency for abnormal lipid levels and high risk of Coronary Artery Disease (CAD). Therefore, the present study aimed to elucidate the relationship of four single nucleotide polymorphisms (SNPs) in the Apo11q cluster, namely the -75G>A, +83C>T SNPs in the APOA1 gene, the Sac1 SNP in the APOC3 gene and the S19W variant in the APOA5 gene to plasma lipids and CAD in 190 affected sibling pairs (ASPs) belonging to Asian Indian families with a strong CAD history. Methods & results Genotyping and lipid assays were carried out using standard protocols. Plasma lipids showed a strong heritability (h2 48% – 70%; P < 0.0001). A subset of 77 ASPs with positive sign of Logarithm of Odds (LOD) score showed significant linkage to CAD trait by multi-point analysis (LOD score 7.42, P < 0.001) and to Sac1 (LOD score 4.49) and -75G>A (LOD score 2.77) SNPs by single-point analysis (P < 0.001). There was significant proportion of mean allele sharing (pi) for the Sac1 (pi 0.59), -75G>A (pi 0.56) and +83C>T (pi 0.52) (P < 0.001) SNPs, respectively. QTL analysis showed suggestive evidence of linkage of the Sac1 SNP to Total Cholesterol (TC), High Density Lipoprotein-cholesterol (HDL-C) and Apolipoprotein B (ApoB) with LOD scores of 1.42, 1.72 and 1.19, respectively (P < 0.01). The Sac1 and -75G>A SNPs along with hypertension showed maximized correlations with TC, TG and Apo B by association analysis. Conclusion The APOC3-Sac1 SNP is an important genetic variant that is associated with CAD through its interaction with plasma lipids and other standard risk factors among Asian Indians. PMID:18801202

Demographic loss, genetic structure and the conservation implications for Indian tigers.

PubMed

Mondol, Samrat; Bruford, Michael W; Ramakrishnan, Uma

2013-07-07

India is home to approximately 60 per cent of the world's remaining wild tigers, a species that has declined in the last few centuries to occupy less than 7 per cent of its former geographical range. While Indian tiger numbers have somewhat stabilized in recent years, they remain low and populations are highly fragmented. Therefore, the application of evidence-based demographic and genetic management to enhance the remaining populations is a priority. In this context, and using genetic data from historical and modern tigers, we investigated anthropogenic impacts on genetic variation in Indian tigers using mitochondrial and nuclear genetic markers. We found a very high number of historical mitochondrial DNA variants, 93 per cent of which are not detected in modern populations. Population differentiation was higher in modern tigers. Simulations incorporating historical data support population decline, and suggest high population structure in extant populations. Decreased connectivity and habitat loss as a result of ongoing fragmentation in the Indian subcontinent has therefore resulted in a loss of genetic variants and increased genetic differentiation among tiger populations. These results highlight that anthropogenic fragmentation and species-specific demographic processes can interact to alter the partitioning of genetic variation over very short time scales. We conclude that ongoing strategies to maximize the size of some tiger populations, at the expense of losing others, is an inadequate conservation strategy, as it could result in a loss of genetic diversity that may be of adaptive significance for this emblematic species.

Demographic loss, genetic structure and the conservation implications for Indian tigers

PubMed Central

Mondol, Samrat; Bruford, Michael W.; Ramakrishnan, Uma

2013-01-01

India is home to approximately 60 per cent of the world's remaining wild tigers, a species that has declined in the last few centuries to occupy less than 7 per cent of its former geographical range. While Indian tiger numbers have somewhat stabilized in recent years, they remain low and populations are highly fragmented. Therefore, the application of evidence-based demographic and genetic management to enhance the remaining populations is a priority. In this context, and using genetic data from historical and modern tigers, we investigated anthropogenic impacts on genetic variation in Indian tigers using mitochondrial and nuclear genetic markers. We found a very high number of historical mitochondrial DNA variants, 93 per cent of which are not detected in modern populations. Population differentiation was higher in modern tigers. Simulations incorporating historical data support population decline, and suggest high population structure in extant populations. Decreased connectivity and habitat loss as a result of ongoing fragmentation in the Indian subcontinent has therefore resulted in a loss of genetic variants and increased genetic differentiation among tiger populations. These results highlight that anthropogenic fragmentation and species-specific demographic processes can interact to alter the partitioning of genetic variation over very short time scales. We conclude that ongoing strategies to maximize the size of some tiger populations, at the expense of losing others, is an inadequate conservation strategy, as it could result in a loss of genetic diversity that may be of adaptive significance for this emblematic species. PMID:23677341

Can genetics help us understand Indian social history?

PubMed

Thapar, Romila

2014-06-26

Attempts have been made recently to determine the identity of the so-called "Aryans" as components of the Indian population by using DNA analysis. This is largely to ascertain whether they were indigenous to India or were foreign arrivals. Similar attempts have been made to trace the origins of caste groups on the basis of varna identities and record their distribution. The results so far have been contradictory and, therefore, not of much help to social historians. There are problems in the defining of categories and the techniques of analysis. Aryan is a linguistic and cultural category and not a biological one. Caste groups have no well-defined and invariable boundaries despite marriage codes. Various other categories have been assimilated into particular castes as part of the evolution of social history on the subcontinent. A few examples of these are discussed. The problems with using DNA analysis are also touched on. Copyright © 2014 Cold Spring Harbor Laboratory Press; all rights reserved.

Spirituality as an ethical challenge in Indian palliative care: A systematic review.

PubMed

Gielen, Joris; Bhatnagar, Sushma; Chaturvedi, Santosh K

2016-10-01

Spiritual care is recognized as an essential component of palliative care (PC). However, patients' experience of spirituality is heavily context dependent. In addition, Western definitions and findings regarding spirituality may not be applicable to patients of non-Western origin, such as Indian PC patients. Given the particular sociocultural, religious, and economic conditions in which PC programs in India operate, we decided to undertake a systematic review of the literature on spirituality among Indian PC patients. We intended to assess how spirituality has been interpreted and operationalized in studies of this population, to determine which dimensions of spirituality are important for patients, and to analyze its ethical implications. In January of 2015, we searched five databases (ATLA, CINAHL, EMBASE, PsycINFO, and PubMed) using a combination of controlled and noncontrolled vocabulary. A content analysis of all selected reports was undertaken to assess the interpretation and dimensions of spirituality. Data extraction from empirical studies was done using a data-extraction sheet. A total of 39 empirical studies (12 qualitative, 21 quantitative, and 6 mixed-methods) and 18 others (10 reviews, 4 opinion articles, and 4 case studies) were retrieved. To date, no systematic review on spirituality in Indian PC has been published. Spirituality was the main focus of only six empirical studies. The content analysis revealed three dimensions of spirituality: (1) the relational dimension, (2) the existential dimension, and (3) the values dimension. Religion is prominent in all these dimensions. Patients' experiences of spirituality are determined by the specifically Indian context, which leads to particular ethical issues. Since spiritual well-being greatly impacts quality of life, and because of the substantial presence of people of Indian origin living outside the subcontinent, the findings of our review have international relevance. Moreover, our review illustrates

Evidence for long-lived subduction of an ancient tectonic plate beneath the southern Indian Ocean: Ancient Slab Beneath the Indian Ocean

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simmons, N. A.; Myers, S. C.; Johannesson, G.

In this study, ancient subducted tectonic plates have been observed in past seismic images of the mantle beneath North America and Eurasia, and it is likely that other ancient slab structures have remained largely hidden, particularly in the seismic-data-limited regions beneath the vast oceans in the Southern Hemisphere. Here we present a new global tomographic image, which shows a slab-like structure beneath the southern Indian Ocean with coherency from the upper mantle to the core-mantle boundary region—a feature that has never been identified. We postulate that the structure is an ancient tectonic plate that sank into the mantle along anmore » extensive intraoceanic subduction zone that migrated southwestward across the ancient Tethys Ocean in the Mesozoic Era. Slab material still trapped in the transition zone is positioned near the edge of East Gondwana at 140 Ma suggesting that subduction terminated near the margin of the ancient continent prior to breakup and subsequent dispersal of its subcontinents.« less

Evidence for long-lived subduction of an ancient tectonic plate beneath the southern Indian Ocean: Ancient Slab Beneath the Indian Ocean

DOE PAGES

Simmons, N. A.; Myers, S. C.; Johannesson, G.; ...

2015-11-14

In this study, ancient subducted tectonic plates have been observed in past seismic images of the mantle beneath North America and Eurasia, and it is likely that other ancient slab structures have remained largely hidden, particularly in the seismic-data-limited regions beneath the vast oceans in the Southern Hemisphere. Here we present a new global tomographic image, which shows a slab-like structure beneath the southern Indian Ocean with coherency from the upper mantle to the core-mantle boundary region—a feature that has never been identified. We postulate that the structure is an ancient tectonic plate that sank into the mantle along anmore » extensive intraoceanic subduction zone that migrated southwestward across the ancient Tethys Ocean in the Mesozoic Era. Slab material still trapped in the transition zone is positioned near the edge of East Gondwana at 140 Ma suggesting that subduction terminated near the margin of the ancient continent prior to breakup and subsequent dispersal of its subcontinents.« less

Multiple Sclerosis in Keralite siblings after migration to the Middle East: a report of familial Multiple Sclerosis from India.

PubMed

Narayan, Sunil K; Kumar, Sudhir; Prabhakar, P; Elangovan, S; Baumann, Nicole; Verma, I C

2007-09-15

To report Multiple Sclerosis (MS) in two migrant Indian siblings in the Middle East. MS was thought to be rare in the Indian subcontinent, but, of late, with ready availability of Magnetic Resonance Imaging (MRI) scan, evoked potential studies and immunoglobulin estimation in this part of the developing world, there have been several reports of definite cases of MS from India. However familial MS remains hitherto unreported from the Indian subcontinent. A 39-year-old South Indian Hindu female presented with an episode of hemiparesis which remitted with treatment. Three months later she had a relapse in an acute disseminated form, with residual deficits in gait, vision and mental faculties. MRI revealed discrete and confluent plaques in the centrum semiovale. Four years later, her brother was diagnosed to have central demyelinating disease with discrete and confluent plaques in the cervical cord and corona radiata when he presented at age 39 with neck pain and episodic tonic spasms in the lower limbs. Leucodystrophies were ruled out through appropriate biochemical tests. Cases satisfied diagnostic criteria for MS and were confirmed by follow up. HLA associations were studied. Starting a decade after migration from the South Indian state of Kerala to the Middle East, the disease had slow secondary progression in the female but a stable benign course, so far, in the male sibling. This is the first case report of familial MS from the Indian subcontinent. Onset of MS in South Indian siblings after several years of stay in the Middle East may support aetiological postulations of gene-environment interactions.

Investigation on the monthly variation of cirrus optical properties over the Indian subcontinent using cloud-aerosol lidar and infrared pathfinder satellite observation (Calipso)

NASA Astrophysics Data System (ADS)

Dhaman, Reji K.; Satyanarayana, Malladi; Jayeshlal, G. S.; Mahadevan Pillai, V. P.; Krishnakumar, V.

2016-05-01

Cirrus clouds have been identified as one of the atmospheric component which influence the radiative processes in the atmosphere and plays a key role in the Earth Radiation Budget. CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation) is a joint NASA-CNES satellite mission designed to provide insight in understanding of the role of aerosols and clouds in the climate system. This paper reports the study on the variation of cirrus cloud optical properties of over the Indian sub - continent for a period of two years from January 2009 to December 2010, using cloud-aerosol lidar and infrared pathfinder satellite observations (Calipso). Indian Ocean and Indian continent is one of the regions where cirrus occurrence is maximum particularly during the monsoon periods. It is found that during the south-west monsoon periods there is a large cirrus cloud distribution over the southern Indian land masses. Also it is observed that the north-east monsoon periods had optical thick clouds hugging the coast line. The summer had large cloud formation in the Arabian Sea. It is also found that the land masses near to the sea had large cirrus presence. These cirrus clouds were of high altitude and optical depth. The dependence of cirrus cloud properties on cirrus cloud mid-cloud temperature and geometrical thickness are generally similar to the results derived from the ground-based lidar. However, the difference in macrophysical parameter variability shows the limits of space-borne-lidar and dissimilarities in regional climate variability and the nature and source of cloud nuclei in different geographical regions.

Diversity in the representation of large-scale circulation associated with ENSO-Indian summer monsoon teleconnections in CMIP5 models

NASA Astrophysics Data System (ADS)

Ramu, Dandi A.; Chowdary, Jasti S.; Ramakrishna, S. S. V. S.; Kumar, O. S. R. U. B.

2018-04-01

Realistic simulation of large-scale circulation patterns associated with El Niño-Southern Oscillation (ENSO) is vital in coupled models in order to represent teleconnections to different regions of globe. The diversity in representing large-scale circulation patterns associated with ENSO-Indian summer monsoon (ISM) teleconnections in 23 Coupled Model Intercomparison Project Phase 5 (CMIP5) models is examined. CMIP5 models have been classified into three groups based on the correlation between Niño3.4 sea surface temperature (SST) index and ISM rainfall anomalies, models in group 1 (G1) overestimated El Niño-ISM teleconections and group 3 (G3) models underestimated it, whereas these teleconnections are better represented in group 2 (G2) models. Results show that in G1 models, El Niño-induced Tropical Indian Ocean (TIO) SST anomalies are not well represented. Anomalous low-level anticyclonic circulation anomalies over the southeastern TIO and western subtropical northwest Pacific (WSNP) cyclonic circulation are shifted too far west to 60° E and 120° E, respectively. This bias in circulation patterns implies dry wind advection from extratropics/midlatitudes to Indian subcontinent. In addition to this, large-scale upper level convergence together with lower level divergence over ISM region corresponding to El Niño are stronger in G1 models than in observations. Thus, unrealistic shift in low-level circulation centers corroborated by upper level circulation changes are responsible for overestimation of ENSO-ISM teleconnections in G1 models. Warm Pacific SST anomalies associated with El Niño are shifted too far west in many G3 models unlike in the observations. Further large-scale circulation anomalies over the Pacific and ISM region are misrepresented during El Niño years in G3 models. Too strong upper-level convergence away from Indian subcontinent and too weak WSNP cyclonic circulation are prominent in most of G3 models in which ENSO-ISM teleconnections are

Indian programme on middle atmosphere - Some results

NASA Astrophysics Data System (ADS)

Mitra, A. P.

An account of the very extensive program on the middle atmosphere carried out in India since 1982 is presented. Three rocket ranges (Thumba, SHAR and Balasore), a high altitude balloon facility at Hyderabad, a lidar at Thumba, a laser heterodyning system at Delhi, a meteor radar in Thumba, a network of UVB and multiwavelength radiometers, and a host of conventional ground based facilities scattered over the entire subcontinent were used. These facilities covered a range of latitudes from 8 deg N to 34 deg N and largely around the same longitude zone of 75 deg E. The nature of the Indian effort is the emphasis on campaign mode operations, knitting special rocket and balloon efforts with more conventional ground based activities around specific themes. Major campaigns carried out included: (1) Indo-Soviet Ozone Intercomparison campaigns in 1983 and 1987, (2) Aerosol campaign (3), Ionization and conductivity campaigns, (4) Equatorial Wave Campaign, (5) Antarctic Ozone Hole campaign in Dakshin Gangotri. A few of the more important findings are outlined.

Different impacts of mega-ENSO and conventional ENSO on the Indian summer rainfall: developing phase

NASA Astrophysics Data System (ADS)

Zhang, Lei; Wu, Zhiwei; Zhou, Yefan

2016-04-01

Mega-El Niño-Southern Oscillation (ENSO), a boarder version of conventional ENSO, is found to be a main driving force of Northern Hemisphere summer monsoon rainfall including the Indian summer rainfall (ISR). The simultaneous impacts of "pure" mega-ENSO and "pure" conventional ENSO events on the ISR in its developing summer remains unclear. This study examines the different linkages between mega-ENSO-ISR and conventional ENSO-ISR. During the developing summer of mega-El Niño, negative rainfall anomalies are seen over the northeastern Indian subcontinent, while the anomalous rainfall pattern is almost the opposite for mega-La Niña; as for the conventional ENSO, the approximate "linear opposite" phenomenon vanishes. Furthermore, the global zonal wave trains anomalous are found at mid-latitude zones, with a local triple circulation pattern over the central-east Eurasia during mega-ENSO events, which might be an explanation of corresponding rainfall response over the Indian Peninsula. Among 106-year historical run (1900-2005) of 9 state-of-the-art models from the Coupled Model Inter-comparison Project Phase 5 (CMIP5), HadGEM2-ES performs a promising skill in simulating the anomalous circulation pattern over mid-latitude and central-east Eurasia while CanESM2 cannot. Probably, it is the models' ability of capturing the mega-ENSO-ISR linkage and the characteristic of mega-ENSO that make the difference.

Diversification of rhacophorid frogs provides evidence for accelerated faunal exchange between India and Eurasia during the Oligocene.

PubMed

Li, Jia-Tang; Li, Yang; Klaus, Sebastian; Rao, Ding-Qi; Hillis, David M; Zhang, Ya-Ping

2013-02-26

The accretion of the Indian subcontinent to Eurasia triggered a massive faunal and floral exchange, with Gondwanan taxa entering into Asia and vice versa. The traditional view on the Indian-Asian collision assumes contact of the continental plates during the Early Eocene. Many biogeographic studies rely on this assumption. However, the exact mode and timing of this geological event is still under debate. Here we address, based on an extensive phylogenetic analysis of rhacophorid tree frogs, if there was already a Paleogene biogeographic link between Southeast Asia and India; in which direction faunal exchange occurred between India and Eurasia within the Rhacophoridae; and if the timing of the faunal exchange correlates with one of the recently suggested geological models. Rhacophorid tree frogs showed an early dispersal from India to Asia between 46 and 57 Ma, as reconstructed from the fossil record. During the Middle Eocene, however, faunal exchange ceased, followed by increase of rhacophorid dispersal events between Asia and the Indian subcontinent during the Oligocene that continued until the Middle Miocene. This corroborates recent geological models that argue for a much later final collision between the continental plates. We predict that the Oligocene faunal exchange between the Indian subcontinent and Asia, as shown here for rhacophorid frogs, also applies for other nonvolant organisms with an Indian-Asian distribution, and suggest that previous studies that deal with this faunal interchange should be carefully reinvestigated.

Coming to America: betel nut and oral submucous fibrosis.

PubMed

Aziz, Shahid R

2010-04-01

Oral submucous fibrosis (OSF) is an insidious precancerous disease affecting the oral cavity, pharynx and upper digestive tract. Its etiology is linked directly to betel nut use, which is common to the Indian subcontinent. With the increase in immigration of people from the Indian subcontinent to the United States, many American dental professionals will encounter this disease in the near future. The author provides a general overview of OSF. The author provides a literature review of OSF, including its epidemiology, etiology, clinical presentation, histopathology and treatment modalities. OSF is a precancerous oral disease linked definitively to the use of betel nut. It is endemic to people in the Indian subcontinent. Patients' primary complaint is progressive trismus. Treatment is based on disease severity. OSF is a debilitating but preventable oral disease. Its incidence in the United States will increase as the South Asian immigrant population expands. Consequently, American dental professionals may encounter patients with this disease, and it is important that they are aware of it. In addition, for dental care professionals practicing in a South Asian American community, public health education is important to inform the population about the deleterious oral health effects of betel nut consumption.

12 CFR 1281.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Indian or Alaskan Native—a person having origins in any of the original peoples of North and South... Indian subcontinent, including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam; (3) Black or African American—a person having origins...

12 CFR 1281.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Indian or Alaskan Native—a person having origins in any of the original peoples of North and South... Indian subcontinent, including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam; (3) Black or African American—a person having origins...

Prediction model for peninsular Indian summer monsoon rainfall using data mining and statistical approaches

NASA Astrophysics Data System (ADS)

Vathsala, H.; Koolagudi, Shashidhar G.

2017-01-01

In this paper we discuss a data mining application for predicting peninsular Indian summer monsoon rainfall, and propose an algorithm that combine data mining and statistical techniques. We select likely predictors based on association rules that have the highest confidence levels. We then cluster the selected predictors to reduce their dimensions and use cluster membership values for classification. We derive the predictors from local conditions in southern India, including mean sea level pressure, wind speed, and maximum and minimum temperatures. The global condition variables include southern oscillation and Indian Ocean dipole conditions. The algorithm predicts rainfall in five categories: Flood, Excess, Normal, Deficit and Drought. We use closed itemset mining, cluster membership calculations and a multilayer perceptron function in the algorithm to predict monsoon rainfall in peninsular India. Using Indian Institute of Tropical Meteorology data, we found the prediction accuracy of our proposed approach to be exceptionally good.

14 CFR 152.403 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... East, Southeast Asia, the Indian subcontinent, or the Pacific Islands, including, but not limited to China, Japan, Korea, the Philippine Islands, and Samoa; or (4) American Indian or Alaskan Native: A... part; Underutilization means having fewer minorities or women in a particular job group than would...

14 CFR 152.403 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... East, Southeast Asia, the Indian subcontinent, or the Pacific Islands, including, but not limited to China, Japan, Korea, the Philippine Islands, and Samoa; or (4) American Indian or Alaskan Native: A... part; Underutilization means having fewer minorities or women in a particular job group than would...

12 CFR 1281.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... categories: (1) American Indian or Alaskan Native—a person having origins in any of the original peoples of..., or the Indian subcontinent, including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam; (3) Black or African American—a person having...

14 CFR 152.403 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... East, Southeast Asia, the Indian subcontinent, or the Pacific Islands, including, but not limited to China, Japan, Korea, the Philippine Islands, and Samoa; or (4) American Indian or Alaskan Native: A... Mexican, Puerto Rican, Cuban, Central or South American or other Spanish culture or origin, regardless of...

Gene diversity in some Muslim populations of North India.

PubMed

Aarzoo, S Shabana; Afzal, Mohammad

2005-06-01

North Indian Muslim populations have historical, linguistic, and socioreligious significance to the Indian subcontinent. Although sociocultural and political dimensions of their demography are well documented, no detailed genetic structure of the populations is available. We have undertaken a survey of the gene frequencies of the ABO, Rh, PTC taste ability, sickling, and G6PD systems for different endogamous groups: Sheikh, Syed, Pathan, Ansari, Saifi, and Hindu Bania. All the groups at most loci showed statistically nonsignificant differences, except for ABO and PTC traits, for which interpopulational differences were seen. Heterozygosity ranged from 0.048 to 0.617 among the Sheikh, 0.149 to 0.599 among the Pathan, 0.105 to 0.585 among the Ansari, 0.25 to 0.869 among the Syed, 0.107 to 0.565 among the Saifi, and 0.100 to 0.492 among the Hindu Bania. The average D(ST) and G(ST) values for the five marker loci were 0.0625 +/- 0.098 and 0.1072 +/- 0.041, respectively. A dendrogram was constructed using the UPGMA clustering method. Our results revealed that the Pathan and the Sheikh form one cluster, the Syed and the Hindu Bania form another cluster, and the two clusters join together (the so-called higher caste); also, the Saifi and the Ansari form a separate cluster (lower caste). The results of the genetic distance analysis are useful for understanding the pattern of genetic relationships between different endogamous groups of Muslims.

Characterization of Different Land Classes and Disaster Monitoring Using Microwave Land Emissivity for the Indian Subcontinent

NASA Astrophysics Data System (ADS)

Saha, Korak; Raju, Suresh; Antony, Tinu; Krishna Moorthy, K.

Despite the ability of satellite borne microwave radiometers to measure the atmospheric pa-rameters, liquid water and the microphysical properties of clouds, they have serious limitations over the land owing its large and spatially heterogeneous emissivity compared to the relatively low and homogenous oceans. This calls for determination of the spatial maps of land-surface emissivity with accuracies better than ˜2%. In this study, the characterization of microwave emissivity of different land surface classes over the Indian region is carried out with the forth-coming Indo-French microwave satellite program Megha-Tropiques in focus. The land emissivity is retrieved using satellite microwave radiometer data from Special Sensor Microwave/Imager (SSM/I) and TRMM Microwave Imager (TMI) at 10, 19, 22, 37 and 85 GHz. After identify-ing the clear sky daily data, the microwave radiative transfer computation, is applied to the respective daily atmospheric profile for deducing the upwelling and downwelling atmospheric radiations. This, along with the skin temperature data, is used to retrieve land emission from satellites data. The emissivity maps of placecountry-regionIndia for three months representing winter (January) and post-monsoon (September-October) seasons of 2008 at V and H polar-izations of all the channels (except for 22 GHz) are generated. Though the land emissivity values in V-polarization vary between 0.5 and ˜1, some land surface classes such as the desert region, marshy land, fresh snow covered region and evergreen forest region, etc, show distinct emissivity characteristics. On this basis few typical classes having uniform physical properties over sufficient area are identified. Usually the Indian desert region is dry and shows low emis-sivity (˜0.88 in H-polarisation) and high polarization difference, V-H (˜0.1). Densely vegetated zones of tropical rain forests exhibit high emissivity values (˜0.95) and low polarization dif-ference (lt;0.01). The

[Tuberculosis among Trio-Indians in Surinam].

PubMed

van Crevel, R; van Doorninck, D J; van Ams, J E; Fat, H Tjon; Vreden, S G; van der Meer, J M

2004-02-28

Evaluation of the extent and possible causes of the increased incidence of tuberculosis among Amazonian Indians in Surinam. Descriptive. In two cross-sectional surveys in 1998 and 2000, the inhabitants of Kwamalasamutu, a village of Trio-Indians in Surinam, were examined for the presence of active and latent tuberculosis. Previous cases from the period 1995-2000 were evaluated retrospectively by consulting individual physicians and the archives of the 'Medische Zending' (Medical Mission), the 'Diakonessenhuis' hospital, the clinic for pulmonary diseases, and the Central Laboratory. Family ties and other factors that might be associated with tuberculosis were examined. Spoligotyping was done on all patient isolates. Between 1995 and 2000, active tuberculosis was diagnosed in 25 Indians from Kwamalasamutu, equal to 4.2 cases/1000 person-years (95% CI: 2.7-6.1). Tuberculin skin tests were positive in 105/733 Indians (14.3%). Cases of tuberculosis were found predominantly within certain families, who were genetically related. Spoligotyping of 5 Mycobacterium tuberculosis isolates from Trio-Indians showed unique patterns, which were also found in 34 isolates from elsewhere in Surinam. Tuberculosis was relatively common among Trio-Indians, clustering in certain families. This isolated tribe may have a genetic predisposition for tuberculosis, but their lifestyle and limited access to health care certainly play a role as well.

Sensitivity of convective precipitation to soil moisture and vegetation during break spell of Indian summer monsoon

NASA Astrophysics Data System (ADS)

Kutty, Govindan; Sandeep, S.; Vinodkumar; Nhaloor, Sreejith

2017-07-01

Indian summer monsoon rainfall is characterized by large intra-seasonal fluctuations in the form of active and break spells in rainfall. This study investigates the role of soil moisture and vegetation on 30-h precipitation forecasts during the break monsoon period using Weather Research and Forecast (WRF) model. The working hypothesis is that reduced rainfall, clear skies, and wet soil condition during the break monsoon period enhance land-atmosphere coupling over central India. Sensitivity experiments are conducted with modified initial soil moisture and vegetation. The results suggest that an increase in antecedent soil moisture would lead to an increase in precipitation, in general. The precipitation over the core monsoon region has increased by enhancing forest cover in the model simulations. Parameters such as Lifting Condensation Level, Level of Free Convection, and Convective Available Potential Energy indicate favorable atmospheric conditions for convection over forests, when wet soil conditions prevail. On spatial scales, the precipitation is more sensitive to soil moisture conditions over northeastern parts of India. Strong horizontal gradient in soil moisture and orographic uplift along the upslopes of Himalaya enhanced rainfall over the east of Indian subcontinent.

Pleistocene Indian Monsoon Rainfall Variability

NASA Astrophysics Data System (ADS)

Yirgaw, D. G.; Hathorne, E. C.; Giosan, L.; Collett, T. S.; Sijingeo, A. V.; Nath, B. N.; Frank, M.

2014-12-01

The past variability of the Indian Monsoon is mostly known from records of wind strength over the Arabian Sea. Here we investigate proxies for fresh water input and runoff in a region of strong monsoon precipitation that is a major moisture source for the east Asian Monsoon. A sediment core obtained by the IODP vessel JOIDES Resolution and a gravity core from the Alcock Seamount complex in the Andaman Sea are used to examine the past monsoon variability on the Indian sub-continent and directly over the ocean. The current dataset covers the last glacial and deglacial but will eventually provide a Pleistocene record. We utilise the ecological habitats of G. sacculifer and N. dutertrei to investigate the freshwater-induced stratification with paired Mg/Ca and δ18O analyses to estimate seawater δ18O (δ18Osw). During the last 60 kyrs, Ba/Ca ratios and δ18Osw values generally agree well between the two cores and suggest the weakest surface runoff and monsoon during the LGM and strongest monsoon during the Holocene. The difference in δ18O between the species, interpreted as a proxy for upper ocean stratification, implies stratification developed around 37 ka and remained relatively constant during the LGM, deglacial and Holocene. To investigate monsoon variability for intervals in the past, single shell Mg/Ca and δ18O analyses have been conducted. Mg/Ca ratios from individual shells of N. dutertrei suggest relatively small changes in temperature. However, individual N. dutertrei δ18O differ greatly between the mid-Holocene and samples from the LGM and a nearby core top. The mid-Holocene individuals have a greater range and large skew towards negative values indicating greater fresh water influence.

Phlebotomus argentipes seasonal patterns in India and Nepal.

PubMed

Picado, Albert; Das, Murari Lal; Kumar, Vijay; Dinesh, Diwakar S; Rijal, Suman; Singh, Shri P; Das, Pradeep; Coosemans, Marc; Boelaert, Marleen; Davies, Clive

2010-03-01

The current control of Phebotomus argentipes (Annandale and Brunetti), the vector of Leishmania donovani (Laveran and Mesnil), on the Indian subcontinent is base on indoor residual spraying. The efficacy of this method depends, among other factors, on the timing and number of spraying rounds, which depend on the P. argentipes seasonality. To describe P. argentipes' seasonal patterns, six visceral leishmaniasis (VL) endemic villages, three in Muzaffarpur and three in Sunsari districts in India and Nepal, respectively, were selected based on accessibility and VL incidence. Ten houses per cluster with the highest P. argentipes density were monitored monthly for 15-16 mo using Center for Disease Control and Prevention light traps. Minimum and maximum temperature and rainfall data for the months January 2006 through December 2007 were collected from the nearest available weather stations. Backwards stepwise regression was used to generate the minimal adequate model for explaining the monthly variation in P. argentipes populations. The seasonality of P. argentipes is similar in India and Nepal, with two annual density peaks around May and October. Monthly P. argentipes density is positively associated with temperature and negatively associated with rainfall in both study sites. The multivariate climate model explained 57% of the monthly vectorial abundance. Vector control programs against P. argentipes (i.e., indoor residual spraying) should take into account the seasonal described here when implementing and monitoring interventions. Monitoring simple meteorological variables (i.e., temperature, rainfall) may allow prediction of VL epidemics on the Indian subcontinent.

Effect of untreated bed nets on blood-fed Phlebotomus argentipes in kala-azar endemic foci in Nepal and India.

PubMed

Picado, Albert; Kumar, Vijay; Das, Murari; Burniston, Ian; Roy, Lalita; Suman, Rijal; Dinesh, Diwakar; Coosemans, Marc; Sundar, Shyam; Shreekant, Kesari; Boelaert, Marleen; Davies, Clive; Cameron, Mary

2009-12-01

Observational studies in the Indian subcontinent have shown that untreated nets may be protective against visceral leishmaniasis (VL). In this study, we evaluated the effect of untreated nets on the blood feeding rates of Phlebotomus argentipes as well as the human blood index (HBI) in VL endemic villages in India and Nepal. The study had a 'before and after intervention' design in 58 households in six clusters. The use of untreated nets reduced the blood feeding rate by 85% (95% CI 76.5-91.1%) and the HBI by 42.2% (95% CI 11.1-62.5%). These results provide circumstantial evidence that untreated nets may provide some degree of personal protection against sand fly bites.

Mid-late Holocene climate variability in the Indian monsoon: Evidence from continental shelf sediments adjacent to Rushikulya river, eastern India

NASA Astrophysics Data System (ADS)

Ankit, Yadav; Kumar, Prem; Anoop, Ambili; Mishra, Praveen K.; Varghese, Saju

2017-04-01

We present elemental and grain-size distributions obtained from the sediment core of the continental shelf adjacent to the Rushikulya river mouth, eastern India to quantify the paleoclimatic changes. The retrieved 1.60 m long well-dated core spans the past ca. 6800 cal BP. The modern spatial distribution of grain size and geochemistry of the inner-mid shelf sediments has been carried out to understand the seafloor morphology and sedimentary processes. Based on the mod- ern investigations, the proportion of particle size (clay vs sand) and variation in elemental values (TiO2 vs Al2O3) has been used to interpret the changes in terrigenous supply. The grain-size and elemental distribution data from the core sediments indicates a period of enhanced surface water runoff from 6800 to 3100 cal BP followed by a drier condition (3100 cal BP to present) suggesting weakening of monsoon. The weakening of the monsoonal strength is coeval with other records from the Indian sub-continent and suggests response of Indian monsoon to changing solar insolation during late Holocene.

Indian Monsoon Low-Pressure Systems Feed Up-and-Over Moisture Transport to the Southwestern Tibetan Plateau

NASA Astrophysics Data System (ADS)

Dong, Wenhao; Lin, Yanluan; Wright, Jonathon S.; Xie, Yuanyu; Xu, Fanghua; Xu, Wenqing; Wang, Yan

2017-11-01

As an integral part of the South Asian summer monsoon system, monsoon low-pressure systems (LPSs) bring large amounts of precipitation to agrarian north and central India during their passage across the subcontinent. In this study, we investigate the role of LPSs in supplying moisture from north and central India to the southwestern Tibetan Plateau (SWTP) and quantify the contribution of these systems to summer rainfall over the SWTP. The results show that more than 60% of total summer rainfall over the SWTP is related to LPS occurrence. LPSs are associated with a 15% rise in average daily rainfall and a 10% rise in rainy days over the SWTP. This relationship is maintained primarily through up-and-over transport, in which convectively lifted moisture over the Indian subcontinent is swept over the SWTP by southwesterly winds in the middle troposphere. LPSs play two roles in supplying up-and-over moisture transport. First, these systems elevate large amounts of water vapor and condensed water to the midtroposphere. Second, the circulations associated with LPSs interact with the background westerlies to induce southwesterly flow in the midtroposphere, transporting elevated moisture and condensate over the Himalayan Mountains. Our findings indicate that LPSs are influential in extending the northern boundary of the South Asian monsoon system across the Himalayas into the interior of the SWTP. The strength of this connection depends on both LPS characteristics and the configuration of the midtropospheric circulation, particularly the prevailing westerlies upstream of the SWTP.

SMMR-SSM/I derived Greenland Sea ice variability: links with Indian and Korean Monsoons

NASA Astrophysics Data System (ADS)

Prabhu, Amita; Oh, Jaiho; Kim, In-won; Kripalani, R. H.; Pandithurai, G.

2018-02-01

Greenland Sea ice area (GRESIA) in boreal autumn and its association with the subsequent summer monsoon rainfall over India and South Korea is assessed for the period 1983-2013. It is found that GRESIA in the month of October has a significant positive relation (correlation coefficient (cc) = 0.45) with the subsequent Indian monsoon rainfall (IMR) while having a significant negative relation (cc = -0.40) with the ensuing Korean monsoon rainfall (KMR). GRESIA episodes in the preceding autumn impact the ensuing summer monsoon rainfall over India (South Korea) adversely (favourably). While central Pacific sea surface temperatures (SSTs) play a mediating role in transmitting the GRESIA signal towards the Indian subcontinent, snow over eastern Eurasia, just north of the Korea-Japan peninsula, plays a mediating role in transmitting the GRESIA signal towards the Korean peninsula. Although, the anomalies of equatorial central Pacific SSTs and eastern Eurasian snow play a crucial role in modulating IMR and KMR respectively, the GRESIA variability also plays a dominant role in modulating the monsoon variability over both the regions. Thus, a combination of autumn GRESIA along with SSTs over the central Pacific and snow over the eastern Eurasia, may possibly serve as a unique precursor to presage Asia's two diverse regional subsystems.

First record of the African-Indian centipede genus Digitipes Attems, 1930 (Scolopendromorpha: Otostigminae) from Myanmar, and the systematic position of a new species based on molecular phylogenetics.

PubMed

Siriwut, Warut; Edgecombe, Gregory D; Sutcharit, Chirasak; Tongkerd, Piyoros; Panha, Somsak

2015-03-11

The first Southeast Asian record of the scolopendrid centipede Digitipes Attems, 1930, has been collected and analyzed based on a new species from Myanmar, males possessing a distomedial process on the ultimate leg femur that is diagnostic of the genus. Digitipes kalewaensis n. sp., described herein, is distinguished from other members of Digitipes by its 2.5 to 2.7 dorsally glabrous antennal articles, an unusually long basal suture on the tooth-plates, absence of a lateral spine on the coxopleural process, and a lack of median and dorso-median spines on the ultimate leg prefemur. Maximum likelihood and Bayesian analyses of two molecular markers (mitochondrial COI and 16S rRNA) supported the proposal of a new species from Myanmar. The phylogenetic tree identifies Digitipes barnabasi from the Western Ghats, India, in a polytomy with members of other genera of Otostigminae (Otostigmus, Ethmostigmus and Rhysida) and a robust Indian-Burmese Digitipes clade in which D. kalewaensis n. sp. is resolved as sister group to a clade composed of most Indian species. Available molecular dates for the diversification of Indian Digitipes are consistent with introduction of the genus into SE Asia when the Indian subcontinent made contact with Myanmar in the early Palaeogene.

A sustainable model for cochlear implantation in the developing world: perspectives from the Indian subcontinent.

PubMed

Sampath Kumar, Raghunandhan; Kameswaran, Mohan

2018-06-01

The overall prevalence of deafness in India is 0.2%, but the prevalence in the southern state of Tamil Nadu is much higher (around 0.6%) because of consanguinity. Especially in India, establishing cochlear implantation as a treatment modality for hearing loss has been a daunting task, but in the last decade, the cochlear implantation program has emerged as an unqualified success in many states, with over 20 000 cochlear implantations done till date. Several states are sponsoring free implants to children under the age of 6 years and below poverty line. Nearly 3000 cochlear implantations have been performed in Tamil Nadu under the Chief Minister's Comprehensive Health Insurance Scheme, with the goal to have a 'deafness free Tamil Nadu' by 2025. This scheme covers nearly 40 million people in rural areas. Valuable lessons have been learnt from this social experiment. One of the cornerstones of this scheme is the method to deliver habilitation via satellite centers in rural areas at the doorstep of the patient. The outcomes in peripheral centers were found to be statistically similar to those in the main center and correlated well with duration of habilitation. Opening up satellite centers for habilitation across the state of Tamil Nadu has greatly helped to improve the attendance and outcomes. The Indian model has been hugely successful and has helped start similar cochlear implantation programs in neighboring countries such as Nepal, Sri Lanka and Bangladesh.

The study of Cutaneous Lupus Erythematosus Disease Area and Severity Index in Indian patients with systemic lupus erythematosus.

PubMed

Salphale, P; Danda, D; Chandrashekar, L; Peter, D; Jayaseeli, N; George, R

2011-12-01

The Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) is a newly described tool used to assess the activity of and damage caused by cutaneous lupus erythematosus (CLE). There is a paucity of data on CLASI from the Indian subcontinent. We sought to determine the applicability of CLASI in specific lesions of CLE in patients with systemic lupus erythematosus (SLE) attending a tertiary care hospital in India. In this prospective, cross-sectional study, 93 patients of SLE with cutaneous lesions were recruited. CLASI activity and damage scores of lupus erythematosus (LE)-specific skin lesions were done in 75 patients with SLE. The mean CLASI activity score was 15.4 ± 9.4 (range 0-39) and the mean damage score was 6.87 ± 7.75 (range 0-30). Higher mean CLASI activity scores were seen in patients with a combination of acute, subacute and chronic CLE and in those with widespread lesions. Patients with longstanding disease and long duration of skin lesions had higher damage scores. This study shows that CLASI is an effective tool to assess cutaneous activity of LE-specific lesions, and the damage caused by them, in Indian patients.

The flip-or-flop boutique: Marine debris on the shores of St Brandon's rock, an isolated tropical atoll in the Indian Ocean.

PubMed

Bouwman, Hindrik; Evans, Steven W; Cole, Nik; Choong Kwet Yive, Nee Sun; Kylin, Henrik

2016-03-01

Isolated coral atolls are not immune from marine debris accumulation. We identified Southeast Asia, the Indian sub-continent, and the countries on the Arabian Sea as most probable source areas of 50 000 items on the shores of St. Brandon's Rock (SBR), Indian Ocean. 79% of the debris was plastics. Flip-flops, energy drink bottles, and compact fluorescent lights (CFLs) were notable item types. The density of debris (0.74 m(-)(1) shore length) is comparable to similar islands but less than mainland sites. Intact CFLs suggests product-facilitated long-range transport of mercury. We suspect that aggregated marine debris, scavenged by the islands from currents and gyres, could re-concentrate pollutants. SBR islets accumulated debris types in different proportions suggesting that many factors act variably on different debris types. Regular cleaning of selected islets will take care of most of the accumulated debris and may improve the ecology and tourism potential. However, arrangements and logistics require more study. Copyright © 2016 Elsevier Ltd. All rights reserved.

Predicting onset and withdrawal of Indian Summer Monsoon in 2016: results of Tipping elements approach

NASA Astrophysics Data System (ADS)

Surovyatkina, Elena; Stolbova, Veronika; Kurths, Jurgen

2017-04-01

The monsoon is the season of rain caused by a global seasonal reverse in winds direction and a change in pressure distribution. The Southwest winds bring summer monsoon to India. The economy of India is able to maintain its GDP in the wake of a good monsoon. However, if monsoon gets delayed by even two weeks, it can spell disaster because the high population depending on agriculture - 70% of its people directly related to farming. Agriculture, in turn, is dependent on the monsoon. Although the rainy season happens annually between June and September, the time of monsoon season's onset and withdrawal varies within a month from year to year. The important feature of the monsoon is that it starts and ends suddenly. Hence, despite enormous progress having been made in predicting monsoon since 1886, it remains a significant scientific challenge. To make predictions of monsoon timing in 2016, we applied our recently developed method [1]. Our approach is based on a teleconnection between the Eastern Ghats (EG) and North Pakistan (NP) - Tipping Elements of Indian Summer Monsoon. Both our predictions - for monsoon onset and withdrawal - were made for the Eastern Ghats region (EG-20N,80E) in the central part of India, while the Indian Meteorological Department forecasts monsoon over Kerala - a state at the southern tip of the Indian subcontinent. Our prediction for monsoon onset was published on May 6-th, 2016 [2]. We predicted the monsoon arrival to the EG on the 13th of June with a deviation of +/-4 days. In fact, monsoon onset was on June 17-th, that was confirmed by information from meteorological stations located around the EG-region. Hence, our prediction of monsoon onset (made 40 days in advance) was correct. We delivered the prediction of monsoon withdrawal on July 27, 2016 [3], announcing the monsoon withdrawal from the EG on October 5-th with a deviation of +/-5 days. The actual monsoon withdrawal started on October 10-th when the relative humidity in the region

Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers.

PubMed

van Hattem, Jarne M; Arcilla, Maris S; Bootsma, Martin Cj; van Genderen, Perry J; Goorhuis, Abraham; Grobusch, Martin P; Molhoek, Nicky; Oude Lashof, Astrid Ml; Schultsz, Constance; Stobberingh, Ellen E; Verbrugh, Henri A; de Jong, Menno D; Melles, Damian C; Penders, John

2016-07-01

The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.

Anomalous intraseasonal events in the thermocline ridge region of Southern Tropical Indian Ocean and their regional impacts

NASA Astrophysics Data System (ADS)

Jayakumar, A.; Gnanaseelan, C.

2012-03-01

The present study explores the mechanisms responsible for the strong intraseasonal cooling events in the Thermocline Ridge region of the southwestern Indian Ocean. Air sea interface and oceanic processes associated with Madden Julian Oscillation are studied using an Ocean General Circulation Model and satellite observations. Sensitivity experiments are designed to understand the ocean response to intraseasonal forcing with a special emphasis on 2002 cooling events, which recorded the strongest intraseasonal perturbations during the last well-observed decade. This event is characterized by anomalous Walker circulation over the tropical Indian Ocean and persistent intraseasonal heat flux anomaly for a longer duration than is typical for similar events (but without any favorable preconditioning of ocean basic state at the interannual timescale). The model heat budget analysis during 1996 to 2007 revealed an in-phase relationship between atmospheric fluxes associated with Madden Julian Oscillation and the subsurface oceanic processes during the intense cooling events of 2002. The strong convection, reduced shortwave radiation and increased evaporation have contributed to the upper ocean heat loss in addition to the slower propagation of active phase of convection, which supported the integration of longer duration of forcing. The sensitivity experiments revealed that dynamic response of ocean through entrainment at the intraseasonal timescale primarily controls the biological response during the event, with oceanic interannual variability playing a secondary role. This study further speculates the role of oceanic intraseasonal variability in the 2002 droughts over Indian subcontinent.

Genetic variants on apolipoprotein gene cluster influence triglycerides with a risk of coronary artery disease among Indians.

PubMed

AshokKumar, Manickaraj; Subhashini, Navaneethan Gnana Veera; SaiBabu, Ramineni; Ramesh, Arabandi; Cherian, Kotturathu Mammen; Emmanuel, Cyril

2010-01-01

Apolipoprotein C3 and apolipoprotien A5 are proteins coded from the APOA1/C3/A4/A5 gene cluster. Sst I polymorphism on apolipoprotein C3 and -1131C polymorphism of apolipoprotien A5 are key variants involved in triglyceride metabolism and cause a significant cardio-metabolic risk. Here, we have evaluated these two variants for their roles in coronary artery disease in patients of the Indian population. The apolipoprotein gene cluster variants were analysed in 416 angiographically determined coronary artery disease patients and matched 416 controls using polymerase chain reaction-restriction fragment length polymorphism. The characteristics of the study subjects were analyzed statistically for their association with the polymorphisms. The alleles were combined as haplotypes and their combined risks were evaluated. The minor allele genotypes of both apolipoprotein C3 (S2) and apolipoprotien A5 (C) had a significant risk for coronary artery disease. The S2 allele genotyped patients had a significantly increased triglyceride level (P < 0.001) and increased triglycerides were observed among both patient and control CC genotype carriers. We identified the haplotype S2/C with a significant increased risk (P < 0.001) to coronary artery disease with increased levels of circulating triglycerides compared to other haplotypes in patients. We conclude that the variants on apolipoprotein C3 and apolipoprotien A5 modulate serum triglyceride levels and increase the risk of coronary artery disease.

The role of potential vorticity anomalies in the Somali Jet on Indian Summer Monsoon Intraseasonal Variability

NASA Astrophysics Data System (ADS)

Rai, P.; Joshi, M.; Dimri, A. P.; Turner, A. G.

2018-06-01

The climate of the Indian subcontinent is dominated by rainfall arising from the Indian summer monsoon (ISM) during June to September. Intraseasonal variability during the monsoon is characterized by periods of heavy rainfall interspersed by drier periods, known as active and break events respectively. Understanding and predicting such events is of vital importance for forecasting human impacts such as water resources. The Somali Jet is a key regional feature of the monsoon circulation. In the present study, we find that the spatial structure of Somali Jet potential vorticity (PV) anomalies varies considerably during active and break periods. Analysis of these anomalies shows a mechanism whereby sea surface temperature (SST) anomalies propagate north/northwestwards through the Arabian Sea, caused by a positive feedback loop joining anomalies in SST, convection, modification of PV by diabatic heating and mixing in the atmospheric boundary layer, wind-stress curl, and ocean upwelling processes. The feedback mechanism is consistent with observed variability in the coupled ocean-atmosphere system on timescales of approximately 20 days. This research suggests that better understanding and prediction of monsoon intraseasonal variability in the South Asian monsoon may be gained by analysis of the day-to-day dynamical evolution of PV in the Somali Jet.

The role of potential vorticity anomalies in the Somali Jet on Indian Summer Monsoon Intraseasonal Variability

NASA Astrophysics Data System (ADS)

Rai, P.; Joshi, M.; Dimri, A. P.; Turner, A. G.

2017-08-01

The climate of the Indian subcontinent is dominated by rainfall arising from the Indian summer monsoon (ISM) during June to September. Intraseasonal variability during the monsoon is characterized by periods of heavy rainfall interspersed by drier periods, known as active and break events respectively. Understanding and predicting such events is of vital importance for forecasting human impacts such as water resources. The Somali Jet is a key regional feature of the monsoon circulation. In the present study, we find that the spatial structure of Somali Jet potential vorticity (PV) anomalies varies considerably during active and break periods. Analysis of these anomalies shows a mechanism whereby sea surface temperature (SST) anomalies propagate north/northwestwards through the Arabian Sea, caused by a positive feedback loop joining anomalies in SST, convection, modification of PV by diabatic heating and mixing in the atmospheric boundary layer, wind-stress curl, and ocean upwelling processes. The feedback mechanism is consistent with observed variability in the coupled ocean-atmosphere system on timescales of approximately 20 days. This research suggests that better understanding and prediction of monsoon intraseasonal variability in the South Asian monsoon may be gained by analysis of the day-to-day dynamical evolution of PV in the Somali Jet.

Evidence of late Palaeocene-early Eocene equatorial rain forest refugia in southern Western Ghats, India.

PubMed

Prasad, V; Farooqui, A; Tripathi, S K M; Garg, R; Thakur, B

2009-11-01

Equatorial rain forests that maintain a balance between speciation and extinction are hot-spots for studies of biodiversity. Western Ghats in southern India have gained attention due to high tropical biodiversity and endemism in their southern most area. We attempted to track the affinities of the pollen fl ora of the endemic plants of Western Ghat area within the fossil palynoflora of late Palaeocene-early Eocene (approximately 55-50 Ma) sedimentary deposits of western and northeastern Indian region. The study shows striking similarity of extant pollen with twenty eight most common fossil pollen taxa of the early Palaeogene. Widespread occurrences of coal and lignite deposits during early Palaeogene provide evidence of existence of well diversified rain forest community and swampy vegetation in the coastal low lying areas all along the western and northeastern margins of the Indian subcontinent. Prevalence of excessive humid climate during this period has been seen as a result of equatorial positioning of Indian subcontinent, superimposed by a long term global warming phase (PETM and EECO) during the early Palaeogene. The study presents clear evidence that highly diversifi ed equatorial rain forest vegetation once widespread in the Indian subcontinent during early Palaeogene times, are now restricted in a small area as a refugia in the southernmost part of the Western Ghat area. High precipitation and shorter periods of dry months seem to have provided suitable environment to sustain lineages of ancient tropical vegetation in this area of Western Ghats in spite of dramatic climatic changes subsequent to the post India-Asia collision and during the Quaternary and Recent times.

A novel CANT1 mutation in three Indian patients with Desbuquois dysplasia Kim type.

PubMed

Singh, Ankur; Kim, Ok-Hwa; Iida, Aritoshi; Park, Woong-Yang; Ikegawa, Shiro; Kapoor, Seema

2015-02-01

Desbuquois dysplasia (DBQD) is a rare skeletal dysplasia characterized by severe short stature, laxity, dislocation of multiple joints and developmental delay. DBQD is clinically heterogeneous. Distinct radiographic hand abnormalities such as the presence of extra-ossification distal to the second metacarpal or normal hand has led to its classification into types 1 and 2. Furthermore, the third type of DBQD, Kim type has been reported which is characterized by short metacarpals and elongated phalanges. However, DBQD Kim type has been exclusively reported in Japanese and Korean and its clinical characteristics remain to be delineated. Mutations in the calcium-activated nucleotidase 1 (CANT1) gene have been reported in all three types of DBQD. Previously reported patients with DBQD Kim type had a common mutation c.676G>A (p.Val226Met), which had a common founder between Japanese and Korean. Here, we report 3 Indian patients with DBQD, Kim type from 2 families which were unrelated to each other. We identified a novel mutation of CANT1, c.467C>T (p.Ser156Phe), in all the patients in the homozygous form. Our results show that DBQD Kim type is not exclusive to East Asians and also report a novel mutation from the Indian subcontinent. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Evaluation of seven common lipid associated loci in a large Indian sib pair study.

PubMed

Rafiq, Sajjad; Venkata, Kranthi Kumar M; Gupta, Vipin; Vinay, D G; Spurgeon, Charles J; Parameshwaran, Smitha; Madana, Sandeep N; Kinra, Sanjay; Bowen, Liza; Timpson, Nicholas J; Smith, George Davey; Dudbridge, Frank; Prabhakaran, Dorairaj; Ben-Shlomo, Yoav; Reddy, K Srinath; Ebrahim, Shah; Chandak, Giriraj R

2012-11-14

Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is important since it would suggest wider relevance for these findings. Given the rising prevalence of metabolic disorders and heart disease in the Indian sub-continent, these studies could be of future clinical relevance. We studied seven common variants associated with a variety of lipid traits in previous GWASs. The study sample comprised of 3178 sib-pairs recruited as participants for the Indian Migration Study (IMS). Associations with various lipid parameters and quantitative traits were analyzed using the Fulker genetic association model. We replicated five of the 7 main effect associations with p-values ranging from 0.03 to 1.97x10(-7). We identified particularly strong association signals at rs662799 in APOA5 (beta=0.18 s.d, p=1.97 x 10(-7)), rs10503669 in LPL (beta =-0.18 s.d, p=1.0 x 10(-4)) and rs780094 in GCKR (beta=0.11 s.d, p=0.001) loci in relation to triglycerides. In addition, the GCKR variant was also associated with total cholesterol (beta=0.11 s.d, p=3.9x10(-4)). We also replicated the association of rs562338 in APOB (p=0.03) and rs4775041 in LIPC (p=0.007) with LDL-cholesterol and HDL-cholesterol respectively. We report associations of five loci with various lipid traits with the effect size consistent with the same reported in Europeans. These results indicate an overlap of genetic effects pertaining to lipid traits across the European and Indian populations.

A comparison of risk factors associated with suicide ideation/attempts in American Indian and White youth in Montana.

PubMed

Manzo, Karen; Tiesman, Hope; Stewart, Jera; Hobbs, Gerald R; Knox, Sarah S

2015-01-01

We examined racial/ethnic and gender-specific associations between suicide ideation/attempts and risky behaviors, sadness/hopelessness, and victimization in Montana American Indian and White youth using 1999-2011 Youth Risk Behavior Survey data. Logistic regression was used to calculate odds ratios and 95% confidence intervals in stratified racial/ethnic-gender groups. The primary results of this study show that although the American Indian youth had more statistically significant suicidal thoughts and attempts than the White youth, they had fewer statistically significant predictors compared to the White youth. Sadness/hopelessness was the strongest, and the only statistically significant, predictor of suicide ideation/attempts common across all four groups. The unhealthy weight control cluster was a significant predictor for the White youth and the American Indian/Alaska Native girls; the alcohol/tobacco/marijuana cluster was a significant predictor for the American Indian boys only. Results show important differences across the groups and indicate directions for future research targeting prevention and intervention.

Well-head arsenic removal units in remote villages of Indian subcontinent: field results and performance evaluation.

PubMed

Sarkar, Sudipta; Gupta, Anirban; Biswas, Ranjan K; Deb, Arun K; Greenleaf, John E; Sengupta, Arup K

2005-05-01

Since 1997, over 135 well-head arsenic removal units have been installed in remote villages in the Indian state of West Bengal bordering Bangladesh. Every component of the arsenic removal treatment system including activated alumina sorbent is procured indigenously. Each unit serves approximately 200-300 households and contains about 100 L of activated alumina. No chemical addition, pH adjustment or electricity is required for operating these units. The arsenic concentration in the influent varies from around 100 microg/L to greater than 500 microg/L. In the treated water, arsenic concentration is consistently below 50 microg/L. The units are capable of removing both arsenites and arsenates from the contaminated groundwater for several months, often exceeding 10,000 bed volumes. In the top portion of the column, the dissolved iron present in ground water is oxidized by atmospheric oxygen into hydrated Fe(III) oxides or HFO particles which in turn selectively bind both As(III) and As(V). Upon exhaustion, these units are regenerated by caustic soda solution followed by acid wash. The arsenic-laden spent regenerant is converted into a small volume sludge (less than 500 g) and contained over a coarse sand filter in the same premise requiring no disposal. Many units have been operating for several years without any significant operational difficulty. The treated water is used for drinking and cooking. Most importantly, the villagers are responsible for the day to day operation and the upkeep of the units.

Regional Climate Model Performance in Simulating Intra-seasonal and Interannual Variability of Indian Summer Monsoon

NASA Astrophysics Data System (ADS)

Bhatla, R.; Ghosh, Soumik; Mall, R. K.; Sinha, P.; Sarkar, Abhijit

2018-05-01

Establishment of Indian summer monsoon (ISM) rainfall passes through the different phases and is not uniformly distributed over the Indian subcontinent. This enhancement and reduction in daily rainfall anomaly over the Indian core monsoon region during peak monsoon season (i.e., July and August) are commonly termed as `active' and `break' phases of monsoon. The purpose of this study is to analyze REGional Climate Model (RegCM) results obtained using the most suitable convective parameterization scheme (CPS) to determine active/break phases of ISM. The model-simulated daily outgoing longwave radiation (OLR), mean sea level pressure (MSLP), and the wind at 850 hPa of spatial resolution of 0.5°× 0.5° are compared with NOAA, NCEP, and EIN15 data, respectively over the South-Asia Co-Ordinated Regional Climate Downscaling EXperiment (CORDEX) region. 25 years (1986-2010) composites of OLR, MSLP, and the wind at 850 hPa are considered from start to the dates of active/break phase and up to the end dates of active/break spell of monsoon. A negative/positive anomaly of OLR with active/break phase is found in simulations with CPSs Emanuel and Mix99 (Grell over land; Emanuel over ocean) over the core monsoon region as well as over Monsoon Convergence Zone (MCZ) of India. The appearance of monsoon trough during active phase over the core monsoon zone and its shifting towards the Himalayan foothills during break phase are also depicted well. Because of multi-cloud function over oceanic region and single cloud function over the land mass, the Mix99 CPSs perform well in simulating the synoptic features during the phases of monsoon.

Population Structure With Localized Haplotype Clusters

PubMed Central

Browning, Sharon R.; Weir, Bruce S.

2010-01-01

We propose a multilocus version of FST and a measure of haplotype diversity using localized haplotype clusters. Specifically, we use haplotype clusters identified with BEAGLE, which is a program implementing a hidden Markov model for localized haplotype clustering and performing several functions including inference of haplotype phase. We apply this methodology to HapMap phase 3 data. With this haplotype-cluster approach, African populations have highest diversity and lowest divergence from the ancestral population, East Asian populations have lowest diversity and highest divergence, and other populations (European, Indian, and Mexican) have intermediate levels of diversity and divergence. These relationships accord with expectation based on other studies and accepted models of human history. In contrast, the population-specific FST estimates obtained directly from single-nucleotide polymorphisms (SNPs) do not reflect such expected relationships. We show that ascertainment bias of SNPs has less impact on the proposed haplotype-cluster-based FST than on the SNP-based version, which provides a potential explanation for these results. Thus, these new measures of FST and haplotype-cluster diversity provide an important new tool for population genetic analysis of high-density SNP data. PMID:20457877

A Carbonate Platform Record of Neogene Paleoenvironmental Changes in the Indian Ocean (Maldives)

NASA Astrophysics Data System (ADS)

Betzler, C.; Kroon, D.; Lindhorst, S.; Reolid, J.; Lüdmann, T.; Eberli, G. P.

2017-12-01

The Maldives Inner Sea is a natural sediment trap which preserves a 25 Myrs record of paleoenvironmental changes in the Indian Ocean. This encompasses records of past changes in sea level, productivity, and circulation, but also of the dust influx. As such, the sedimentary succession, which has been cored during IODP Expedition 359, provides the opportunity to study the evolution and the dynamics of the South Asian Monsoon. This amends the reconstruction developed in other, mainly siliciclastic records such as in the Bengal and Indus fan deposits. Seismic-, downhole-, and core data show that windblown dust has been deposited in the Maldives since 22 Ma. However, from 22 to 13 Ma the sedimentation in the Maldives under a weak monsoon was mainly controlled by sea level changes. At 13 Ma this situation changed, and wind driven currents started to control sedimentation, as reflected by the onset of widespread drift deposits. This is interpreted to reflect a more vigorous atmospheric circulation. Linked to the current onset, there was a rise of productivity and a coeval expansion of the oxygen minimum zone. Changes in magnetic susceptibility during the Late Miocene and Pliocene, as imaged in downhole magnetic susceptibility logs are interpreted to reflect fluctuations of the dust influx, mainly from the Indian subcontinent. The combination of XRF data and non-carbonate grain-size data allows a further and detailed reconstruction of variations in the dust influx and bottom-current changes for the last 4 Myrs.

In vivo evaluation of some biophysical parameters of the facial skin of Indian women. Part I: variability with age and geographical locations.

PubMed

Colomb, L; Flament, F; Wagle, A; Agrawal, D

2018-02-01

India is a large country (a subcontinent) of about 3.3 million km 2 that covers large ranges in latitude and longitude. The last Indian census counted about 1.21 billion of inhabitants of many origins, creating a vast human diversity and skin types, the variability of which having been previously established. The present study aimed at deepening this knowledge through a set of biophysical measurements to describe, along the skin ageing process, the specificities of various Indian subjects living in different geographical locations. A total of 1204 women, aged 18-84 years, of all socio-economic status, were recruited in four Indian cities (Mumbai, Kolkata, Chennai and Delhi). Measurements of face skin colour properties, elastic properties, sebum production, skin pores and microrelief roughness were performed. With regard skin colour, this study indicates, with age, a darkening of very low amplitude that leads to an increased skin colour heterogeneity. In all subjects, at all ages, the ocular region (dark circles) presents a much darker pigmentation than the cheeks, creating a contrast that appears constant at all ages. In addition to an increased skin colour heterogeneity, a progressive alteration of the skin surface relief, increased sizes of skin pores, a loss of skin elasticity and a drop in sebum production, post-menopause, are observed. This study confirms, in Indian women, some skin ageing measurements found on women from other ethnic groups (i.e. sebum, firmness, wrinkles and pores size) and also identifies some Indian specificities: a high and constant contrast between the ocular region and the cheek colour, associated to a very slow darkening effect along the lifespan. © 2017 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

Anthropometric and Radiologic Measurements of Coracoid Dimensions and Clinical Implications in an Indian Population.

PubMed

Joshi, Deepak; Gupta, Lalit Mohan; Tanwar, Milind; Lal, Ajay; Chaudhary, Deepak

2018-03-01

Recurrent shoulder dislocation and anterior instability are most commonly attributed to pathology of the capsulolabral complex with the presence of bony loss at the humeral and glenoid surfaces. Unassessed bone loss has been a cause of failure of primary soft tissue procedures or recurrence of symptoms, despite adequate address of soft tissue pathology. To study the anthropometric and radiologic dimensions of the coracoid in relation to glenoid bone loss, its adequacy in filling glenoid defects in an Indian population, and whether the choice of surgical technique (congruent arc vs classical) and graft positioning alters the surgical results. This study also intended to establish whether computed tomography measurements correlate with actual anthropometric measurements. Cross-sectional study; Level of evidence, 3. A total of 64 participants with 108 healthy shoulders were included in this study. Additionally, 100 skeletally mature bone specimens of the scapula were measured to assess glenoid diameter as well as coracoid width and length in 2 perpendicular planes with a humeral subtraction 3-dimensional en face glenoid view. Specimen and participant measurements proved that the congruent arc technique was able to fill up to 50% more glenoid bone loss than the classical technique in an Indian population (mean ± SD, 13.45 ± 6.97 vs 7.96 ± 4.89 mm, respectively), with computed tomography being the best and most accurate modality to study it. The mean difference in the bone block length restoration of the glenoid bony arc was 5.41 ± 2.08 mm. Radii of curvature were congruent in populations of the Indian subcontinent. The congruent arc technique can be performed in an Indian population but with caution and careful presurgical assessment of bone loss. However, adequate coracoid dimension to accommodate the implant for fixation without failure must be ensured, as anthropometry suggests the existence of a subset of the population in whom the graft may have compromised

Predicting Indian Summer Monsoon onset through variations of surface air temperature and relative humidity

NASA Astrophysics Data System (ADS)

Stolbova, Veronika; Surovyatkina, Elena; Kurths, Jurgen

2015-04-01

Indian Summer Monsoon (ISM) rainfall has an enormous effect on Indian agriculture, economy, and, as a consequence, life and prosperity of more than one billion people. Variability of the monsoonal rainfall and its onset have a huge influence on food production, agricultural planning and GDP of the country, which on 22% is determined by agriculture. Consequently, successful forecasting of the ISM onset is a big challenge and large efforts are being put into it. Here, we propose a novel approach for predictability of the ISM onset, based on critical transition theory. The ISM onset is defined as an abrupt transition from sporadious rainfall to spatially organized and temporally sustained rainfall. Taking this into account, we consider the ISM onset as is a critical transition from pre-monsoon to monsoon, which take place in time and also in space. It allows us to suggest that before the onset of ISM on the Indian subcontinent should be areas of critical behavior where indicators of the critical transitions can be detected through an analysis of observational data. First, we identify areas with such critical behavior. Second, we use detected areas as reference points for observation locations for the ISM onset prediction. Third, we derive a precursor for the ISM onset based on the analysis of surface air temperature and relative humidity variations in these reference points. Finally, we demonstrate the performance of this precursor on two observational data sets. The proposed approach allows to determine ISM onset in advance in 67% of all considered years. Our proposed approach is less effective during the anomalous years, which are associated with weak/strong monsoons, e.g. El-Nino, La-Nina or positive Indian Ocean Dipole events. The ISM onset is predicted for 23 out of 27 normal monsoon years (85%) during the past 6 decades. In the anomalous years, we show that time series analysis in both areas during the pre-monsoon period reveals indicators whether the

Diversification of rhacophorid frogs provides evidence for accelerated faunal exchange between India and Eurasia during the Oligocene

PubMed Central

Li, Jia-Tang; Li, Yang; Klaus, Sebastian; Rao, Ding-Qi; Hillis, David M.; Zhang, Ya-Ping

2013-01-01

The accretion of the Indian subcontinent to Eurasia triggered a massive faunal and floral exchange, with Gondwanan taxa entering into Asia and vice versa. The traditional view on the Indian–Asian collision assumes contact of the continental plates during the Early Eocene. Many biogeographic studies rely on this assumption. However, the exact mode and timing of this geological event is still under debate. Here we address, based on an extensive phylogenetic analysis of rhacophorid tree frogs, if there was already a Paleogene biogeographic link between Southeast Asia and India; in which direction faunal exchange occurred between India and Eurasia within the Rhacophoridae; and if the timing of the faunal exchange correlates with one of the recently suggested geological models. Rhacophorid tree frogs showed an early dispersal from India to Asia between 46 and 57 Ma, as reconstructed from the fossil record. During the Middle Eocene, however, faunal exchange ceased, followed by increase of rhacophorid dispersal events between Asia and the Indian subcontinent during the Oligocene that continued until the Middle Miocene. This corroborates recent geological models that argue for a much later final collision between the continental plates. We predict that the Oligocene faunal exchange between the Indian subcontinent and Asia, as shown here for rhacophorid frogs, also applies for other nonvolant organisms with an Indian–Asian distribution, and suggest that previous studies that deal with this faunal interchange should be carefully reinvestigated. PMID:23401521

34 CFR 303.19 - Indian; Indian tribe.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false Indian; Indian tribe. 303.19 Section 303.19 Education... DISABILITIES General Definitions Used in This Part § 303.19 Indian; Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or State Indian tribe, band...

34 CFR 303.19 - Indian; Indian tribe.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false Indian; Indian tribe. 303.19 Section 303.19 Education... DISABILITIES General Definitions Used in This Part § 303.19 Indian; Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or State Indian tribe, band...

34 CFR 303.19 - Indian; Indian tribe.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Indian; Indian tribe. 303.19 Section 303.19 Education... DISABILITIES General Definitions Used in This Part § 303.19 Indian; Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or State Indian tribe, band...

Curcumin: the Indian solid gold.

PubMed

Aggarwal, Bharat B; Sundaram, Chitra; Malani, Nikita; Ichikawa, Haruyo

2007-01-01

Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in the Indian subcontinent, not only for health care but also for the preservation of food and as a yellow dye for textiles. Curcumin, which gives the yellow color to turmeric, was first isolated almost two centuries ago, and its structure as diferuloylmethane was determined in 1910. Since the time of Ayurveda (1900 Bc) numerous therapeutic activities have been assigned to turmeric for a wide variety of diseases and conditions, including those of the skin, pulmonary, and gastrointestinal systems, aches, pains, wounds, sprains, and liver disorders. Extensive research within the last half century has proven that most of these activities, once associated with turmeric, are due to curcumin. Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities and thus has a potential against various malignant diseases, diabetes, allergies, arthritis, Alzheimer's disease, and other chronic illnesses. These effects are mediated through the regulation of various transcription factors, growth factors, inflammatory cytokines, protein kinases, and other enzymes. Curcumin exhibits activities similar to recently discovered tumor necrosis factor blockers (e.g., HUMIRA, REMICADE, and ENBREL), a vascular endothelial cell growth factor blocker (e.g., AVASTIN), human epidermal growth factor receptor blockers (e.g., ERBITUX, ERLOTINIB, and GEFTINIB), and a HER2 blocker (e.g., HERCEPTIN). Considering the recent scientific bandwagon that multitargeted therapy is better than monotargeted therapy for most diseases, curcumin can be considered an ideal "Spice for Life".

The 4-5 day mode oscillation in zonal winds of Indian middle atmosphere during MONEX-79

NASA Astrophysics Data System (ADS)

Reddy, R. S.; Mukherjee, B. K.; Indira, K.; Murty, B. V. R.

1985-12-01

In the early studies based on time series of balloon observations, the existence of 4 to 5 day period waves and 10 to 20 day wind fluctuations were found in the tropical lower stratosphere, and they are identified theoretically as the mixed Rossby-gravity wave and the Kelvin wave, respectively. On the basis of these studies, it was established that the vertically propagating equatorial waves play an important role in producing the QBO (quasi-biennial oscillation) in the mean zonal wind through the mechanism of wave-zonal interaction. These studies are mainly concentrated over the equatorial Pacific and Atlantic Oceans. Similar prominent wave disturbances have been observed over the region east of the Indian Ocean during a quasi-biennial oscillation. Zonal winds in upper troposphere and lower stratosphere (10 to 20) km of the middle atmosphere over the Indian subcontinent may bear association with the activity of summer monsoon (June-September). Monsoon Experiment (MONEX-79) has provided upper air observations at Balasore (21 deg. 30 min.N; 85 deg. 56 min.E), during the peak of monsoon months July and August. A unique opportunity has, therefore, been provided to study the normal oscillations present in the zonal winds of lower middle atmosphere over India, which may have implication on large scale wave dynamics. This aspect is examined in the present study.

Whole Genome Sequencing Demonstrates Limited Transmission within Identified Mycobacterium tuberculosis Clusters in New South Wales, Australia

PubMed Central

Gurjav, Ulziijargal; Outhred, Alexander C.; Jelfs, Peter; McCallum, Nadine; Wang, Qinning; Hill-Cawthorne, Grant A.; Marais, Ben J.; Sintchenko, Vitali

2016-01-01

Australia has a low tuberculosis incidence rate with most cases occurring among recent immigrants. Given suboptimal cluster resolution achieved with 24-locus mycobacterium interspersed repetitive unit (MIRU-24) genotyping, the added value of whole genome sequencing was explored. MIRU-24 profiles of all Mycobacterium tuberculosis culture-confirmed tuberculosis cases diagnosed between 2009 and 2013 in New South Wales (NSW), Australia, were examined and clusters identified. The relatedness of cases within the largest MIRU-24 clusters was assessed using whole genome sequencing and phylogenetic analyses. Of 1841 culture-confirmed TB cases, 91.9% (1692/1841) had complete demographic and genotyping data. East-African Indian (474; 28.0%) and Beijing (470; 27.8%) lineage strains predominated. The overall rate of MIRU-24 clustering was 20.1% (340/1692) and was highest among Beijing lineage strains (35.7%; 168/470). One Beijing and three East-African Indian (EAI) clonal complexes were responsible for the majority of observed clusters. Whole genome sequencing of the 4 largest clusters (30 isolates) demonstrated diverse single nucleotide polymorphisms (SNPs) within identified clusters. All sequenced EAI strains and 70% of Beijing lineage strains clustered by MIRU-24 typing demonstrated distinct SNP profiles. The superior resolution provided by whole genome sequencing demonstrated limited M. tuberculosis transmission within NSW, even within identified MIRU-24 clusters. Routine whole genome sequencing could provide valuable public health guidance in low burden settings. PMID:27737005

Strategic Stability in South Asia: An Indian?s Perspective.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanwal, Gurmeet

The security environment in South Asia has been marked by instability for several decades. The foremost causes of regional instability are the nuclear weapons-cum-missile development program of China, North Korea and Pakistan, the strident march of Islamist fundamentalism, the diabolical nexus between narcotics trafficking and terrorism, the proliferation of small arms and the instability inherent in the rule of despotic regimes. Instability on the Indian sub-continent is manifested, first and foremost, in the continuing conflict in Afghanistan, its tense relations with Iran and the Central Asian Republics (CARs); Pakistan’s struggle against the Taliban, the emerging fissiparous tendencies in Balochistan andmore » Pakhtoonkhwa, the rise of Jihadi Islam and what some fear is Pakistan’s gradual slide towards becoming a ‘failed state’ despite some economic gains in the last five years. Also symptomatic of an unstable and uncertain security environment in the South Asian region are what some see as Sri Lanka’s inability to find a lasting solution to its internal challenges; the potential for Bangladesh’s gradual emergence as the new hub of Islamist fundamentalist terrorism and its struggle for economic upliftment to subsistence levels; the continuing negative impact of Maoist insurgency on Nepal’s fledgling democracy; the simmering discontent in Tibet and Xinjiang and what some see as a low-key uprising against China’s regime; and, the Myanmar peoples’ nascent movement for democracy. In all these countries, socio-economic development has been slow and, consequently, per capita income is alarmingly low. Transborder narcotics trafficking – the golden triangle lies to the east of South Asia and the golden crescent to its west – and the proliferation of small arms, make a potent cocktail. Ethnic tensions and fairly widespread radicalization, worsened by the advent of the vicious ideology of the Islamic state, add further to regional instability.« less

Oral glucose tolerance test significantly impacts the prevalence of abnormal glucose tolerance among Indian women with polycystic ovary syndrome: lessons from a large database of two tertiary care centers on the Indian subcontinent.

PubMed

Ganie, Mohd Ashraf; Dhingra, Atul; Nisar, Sobia; Sreenivas, Vishnubhatla; Shah, Zaffar Amin; Rashid, Aafia; Masoodi, Shariq; Gupta, Nandita

2016-01-01

To estimate the prevalence of abnormal glucose tolerance (AGT) among Indian women with polycystic ovary syndrome (PCOS) and analyze the role of oral glucose tolerance (OGTT) test on its estimation. Cross-sectional clinical study. Tertiary care center. A total of 2,014 women with PCOS diagnosed on the basis of the Rotterdam 2003 criteria were enrolled, and the data of 1,746 subjects were analyzed. In addition to recording clinical, biochemical, and hormone parameters, a 75 g OGTT was administered. Prevalence of AGT and impact of age, body mass index (BMI), family history, and OGTT on its prevalence. The mean age of subjects was 23.8 ± 5.3 years, with a mean BMI of 24.9 ± 4.4 kg/m(2). The overall prevalence of AGT was 36.3% (6.3% diabetes and 30% impaired fasting plasma glucose/impaired glucose tolerance) using American Diabetes Association criteria. The glucose intolerance showed a rising trend with advancing age (30.3%, 35.4%, 51%, and 58.8% in the second, third, fourth, and fifth decades, respectively) and increasing BMI. Family history of diabetes mellitus was present in 54.6% (953/1,746) subjects, and it did not correlate with any of the studied parameters except waist circumference and BMI. Sensitivity was better with 2-hour post-OGTT glucose values as compared with fasting plasma glucose, since using fasting plasma glucose alone would have missed the diagnosis in 107 (6.1%) subjects. We conclude that AGT is high among young Indian women with PCOS and that it is not predicted by family history of type 2 DM. OGTT significantly improves the detection rate of AGT among Indian women with PCOS. Copyright © 2016. Published by Elsevier Inc.

Evaluation of seven common lipid associated loci in a large Indian sib pair study

PubMed Central

2012-01-01

Background Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is important since it would suggest wider relevance for these findings. Given the rising prevalence of metabolic disorders and heart disease in the Indian sub-continent, these studies could be of future clinical relevance. Methods We studied seven common variants associated with a variety of lipid traits in previous GWASs. The study sample comprised of 3178 sib-pairs recruited as participants for the Indian Migration Study (IMS). Associations with various lipid parameters and quantitative traits were analyzed using the Fulker genetic association model. Results We replicated five of the 7 main effect associations with p-values ranging from 0.03 to 1.97x10-7. We identified particularly strong association signals at rs662799 in APOA5 (beta=0.18 s.d, p=1.97 x 10-7), rs10503669 in LPL (beta =−0.18 s.d, p=1.0 x 10-4) and rs780094 in GCKR (beta=0.11 s.d, p=0.001) loci in relation to triglycerides. In addition, the GCKR variant was also associated with total cholesterol (beta=0.11 s.d, p=3.9x10-4). We also replicated the association of rs562338 in APOB (p=0.03) and rs4775041 in LIPC (p=0.007) with LDL-cholesterol and HDL-cholesterol respectively. Conclusions We report associations of five loci with various lipid traits with the effect size consistent with the same reported in Europeans. These results indicate an overlap of genetic effects pertaining to lipid traits across the European and Indian populations. PMID:23150898

Role of Ocean Initial Conditions to Diminish Dry Bias in the Seasonal Prediction of Indian Summer Monsoon Rainfall: A Case Study Using Climate Forecast System

NASA Astrophysics Data System (ADS)

Koul, Vimal; Parekh, Anant; Srinivas, G.; Kakatkar, Rashmi; Chowdary, Jasti S.; Gnanaseelan, C.

2018-03-01

Coupled models tend to underestimate Indian summer monsoon (ISM) rainfall over most of the Indian subcontinent. Present study demonstrates that a part of dry bias is arising from the discrepancies in Oceanic Initial Conditions (OICs). Two hindcast experiments are carried out using Climate Forecast System (CFSv2) for summer monsoons of 2012-2014 in which two different OICs are utilized. With respect to first experiment (CTRL), second experiment (AcSAL) differs by two aspects: usage of high-resolution atmospheric forcing and assimilation of only ARGO observed temperature and salinity profiles for OICs. Assessment of OICs indicates that the quality of OICs is enhanced due to assimilation of actual salinity profiles. Analysis reveals that AcSAL experiment showed 10% reduction in the dry bias over the Indian land region during the ISM compared to CTRL. This improvement is consistently apparent in each month and is highest for June. The better representation of upper ocean thermal structure of tropical oceans at initial stage supports realistic upper ocean stability and mixing. Which in fact reduced the dominant cold bias over the ocean, feedback to air-sea interactions and land sea thermal contrast resulting better representation of monsoon circulation and moisture transport. This reduced bias of tropospheric moisture and temperature over the Indian land mass and also produced better tropospheric temperature gradient over land as well as ocean. These feedback processes reduced the dry bias in the ISM rainfall. Study concludes that initializing the coupled models with realistic OICs can reduce the underestimation of ISM rainfall prediction.

Indian Government and Indian Education.

ERIC Educational Resources Information Center

Starblanket, Noel V.

1981-01-01

Accountability for Indian education must be shared among the chiefs and their councils, the Indian leaders at all levels, parents and students. This may be accomplished by Indian control of Indian education. Available from: Department of Educational Foundations, 5-109 Education North, University of Alberta, Edmonton, AB, Canada, T6G 2G5. (ERB)

34 CFR 300.21 - Indian and Indian tribe.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Indian and Indian tribe. 300.21 Section 300.21 Education... DISABILITIES General Definitions Used in This Part § 300.21 Indian and Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or State Indian tribe, band...

34 CFR 300.21 - Indian and Indian tribe.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Indian and Indian tribe. 300.21 Section 300.21 Education... DISABILITIES General Definitions Used in This Part § 300.21 Indian and Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or State Indian tribe, band...

The Indian origin of paternal haplogroup R1a1* substantiates the autochthonous origin of Brahmins and the caste system.

PubMed

Sharma, Swarkar; Rai, Ekta; Sharma, Prithviraj; Jena, Mamata; Singh, Shweta; Darvishi, Katayoon; Bhat, Audesh K; Bhanwer, A J S; Tiwari, Pramod Kumar; Bamezai, Rameshwar N K

2009-01-01

Many major rival models of the origin of the Hindu caste system co-exist despite extensive studies, each with associated genetic evidences. One of the major factors that has still kept the origin of the Indian caste system obscure is the unresolved question of the origin of Y-haplogroup R1a1*, at times associated with a male-mediated major genetic influx from Central Asia or Eurasia, which has contributed to the higher castes in India. Y-haplogroup R1a1* has a widespread distribution and high frequency across Eurasia, Central Asia and the Indian subcontinent, with scanty reports of its ancestral (R*, R1* and R1a*) and derived lineages (R1a1a, R1a1b and R1a1c). To resolve these issues, we screened 621 Y-chromosomes (of Brahmins occupying the upper-most caste position and schedule castes/tribals occupying the lower-most positions) with 55 Y-chromosomal binary markers and seven Y-microsatellite markers and compiled an extensive dataset of 2809 Y-chromosomes (681 Brahmins, and 2128 tribals and schedule castes) for conclusions. A peculiar observation of the highest frequency (up to 72.22%) of Y-haplogroup R1a1* in Brahmins hinted at its presence as a founder lineage for this caste group. Further, observation of R1a1* in different tribal population groups, existence of Y-haplogroup R1a* in ancestors and extended phylogenetic analyses of the pooled dataset of 530 Indians, 224 Pakistanis and 276 Central Asians and Eurasians bearing the R1a1* haplogroup supported the autochthonous origin of R1a1 lineage in India and a tribal link to Indian Brahmins. However, it is important to discover novel Y-chromosomal binary marker(s) for a higher resolution of R1a1* and confirm the present conclusions.

Molecular phylogeny of the subgenus Ceratotropis (genus Vigna, Leguminosae) reveals three eco-geographical groups and Late Pliocene-Pleistocene diversification: evidence from four plastid DNA region sequences.

PubMed

Javadi, Firouzeh; Tun, Ye Tun; Kawase, Makoto; Guan, Kaiyun; Yamaguchi, Hirofumi

2011-08-01

The subgenus Ceratotropis in the genus Vigna is widely distributed from the Himalayan highlands to South, Southeast and East Asia. However, the interspecific and geographical relationships of its members are poorly understood. This study investigates the phylogeny and biogeography of the subgenus Ceratotropis using chloroplast DNA sequence data. Sequence data from four intergenic spacer regions (petA-psbJ, psbD-trnT, trnT-trnE and trnT-trnL) of chloroplast DNA, alone and in combination, were analysed using Bayesian and parsimony methods. Divergence times for major clades were estimated with penalized likelihood. Character evolution was examined by means of parsimony optimization and MacClade. Parsimony and Bayesian phylogenetic analyses on the combined data demonstrated well-resolved species relationships in which 18 Vigna species were divided into two major geographical clades: the East Asia-Southeast Asian clade and the Indian subcontinent clade. Within these two clades, three well-supported eco-geographical groups, temperate and subtropical (the East Asia-Southeast Asian clade) and tropical (the Indian subcontinent clade), are recognized. The temperate group consists of V. minima, V. nepalensis and V. angularis. The subtropical group comprises the V. nakashimae-V. riukiuensis-V. minima subgroup and the V. hirtella-V. exilis-V. umbellata subgroup. The tropical group contains two subgroups: the V. trinervia-V. reflexo-pilosa-V. trilobata subgroup and the V. mungo-V. grandiflora subgroup. An evolutionary rate analysis estimated the divergence time between the East Asia-Southeast Asia clade and the Indian subcontinent clade as 3·62 ± 0·3 million years, and that between the temperate and subtropical groups as 2·0 ± 0·2 million years. The findings provide an improved understanding of the interspecific relationships, and ecological and geographical phylogenetic structure of the subgenus Ceratotropis. The quaternary diversification of the subgenus Ceratotropis

Inferring Phylogenetic Relationships of Indian Citron (Citrus medica L.) based on rbcL and matK Sequences of Chloroplast DNA.

PubMed

Uchoi, Ajit; Malik, Surendra Kumar; Choudhary, Ravish; Kumar, Susheel; Rohini, M R; Pal, Digvender; Ercisli, Sezai; Chaudhury, Rekha

2016-06-01

Phylogenetic relationships of Indian Citron (Citrus medica L.) with other important Citrus species have been inferred through sequence analyses of rbcL and matK gene region of chloroplast DNA. The study was based on 23 accessions of Citrus genotypes representing 15 taxa of Indian Citrus, collected from wild, semi-wild, and domesticated stocks. The phylogeny was inferred using the maximum parsimony (MP) and neighbor-joining (NJ) methods. Both MP and NJ trees separated all the 23 accessions of Citrus into five distinct clusters. The chloroplast DNA (cpDNA) analysis based on rbcL and matK sequence data carried out in Indian taxa of Citrus was useful in differentiating all the true species and species/varieties of probable hybrid origin in distinct clusters or groups. Sequence analysis based on rbcL and matK gene provided unambiguous identification and disposition of true species like C. maxima, C. medica, C. reticulata, and related hybrids/cultivars. The separation of C. maxima, C. medica, and C. reticulata in distinct clusters or sub-clusters supports their distinctiveness as the basic species of edible Citrus. However, the cpDNA sequence analysis of rbcL and matK gene could not find any clear cut differentiation between subgenera Citrus and Papeda as proposed in Swingle's system of classification.

Frequent occurrence of tomato leaf curl New Delhi virus in cotton leaf curl disease affected cotton in Pakistan

USDA-ARS?s Scientific Manuscript database

Cotton leaf curl disease (CLCuD) in the Indian subcontinent is associated with several distinct monopartite begomoviruses and DNA satellites. However, only a single begomovirus was associated with breakdown of resistance against CLCuD in previously resistant cotton varieties. The monopartite begomov...

Seroprevalence and determinants of Kaposi sarcoma-associated human herpesvirus 8 in Indian HIV-infected males.

PubMed

Munawwar, Arshi; Sharma, Surendra K; Gupta, Somesh; Singh, Sarman

2014-12-01

In India Kaposi's sarcoma is rarely seen in AIDS patients. Hence the current belief is that the incidence of human herpesvirus-8 (HHV-8) is very low in this subcontinent, most probably due to the heterosexual route of HIV transmission. However, there is a scarcity of data on the prevalence of HHV-8 in India. In India the primary mode of HIV transmission is the heterosexual route. Therefore we aimed to determine the prevalence of antibodies against HHV-8 in North Indian HIV-infected men naive of antiretroviral therapy (ART). In a prospective study, 165 Indian adult males were recruited from an ART clinic. Blood samples were collected before administering any antiretroviral drug. The sera were tested for antibodies against HHV-8 using a commercial enzyme-linked immunosorbent assay (ELISA) kit, which detects IgG antibodies to lytic antigens of HHV-8. All positive samples were confirmed for the presence of anti-HHV-8 antibodies using an indirect immunofluorescence assay (IFA). The IFA kit is intended to detect primary, latent, persistent, or reactivated infection of HHV-8. Of the 165 males, 43 (26.06%) were positive by ELISA while 26 (15.8%) were also positive by IFA. Seroprevalence decreased with increasing age (p<0.05). Factors independently associated with HHV-8 infection were younger age group and alcohol consumption. These findings suggest that even in a heterosexual population, HHV-8 can be transmitted frequently.

Genetic diversity trend in Indian rice varieties: an analysis using SSR markers.

PubMed

Singh, Nivedita; Choudhury, Debjani Roy; Tiwari, Gunjan; Singh, Amit Kumar; Kumar, Sundeep; Srinivasan, Kalyani; Tyagi, R K; Sharma, A D; Singh, N K; Singh, Rakesh

2016-09-05

The knowledge of the extent and pattern of diversity in the crop species is a prerequisite for any crop improvement as it helps breeders in deciding suitable breeding strategies for their future improvement. Rice is the main staple crop in India with the large number of varieties released every year. Studies based on the small set of rice genotypes have reported a loss in genetic diversity especially after green revolution. However, a detailed study of the trend of diversity in Indian rice varieties is lacking. SSR markers have proven to be a marker of choice for studying the genetic diversity. Therefore, the present study was undertaken with the aim to characterize and assess trends of genetic diversity in a large set of Indian rice varieties (released between 1940-2013), conserved in the National Gene Bank of India using SSR markers. A set of 729 Indian rice varieties were genotyped using 36 HvSSR markers to assess the genetic diversity and genetic relationship. A total of 112 alleles was amplified with an average of 3.11 alleles per locus with mean Polymorphic Information Content (PIC) value of 0.29. Cluster analysis grouped these varieties into two clusters whereas the model based population structure divided them into three populations. AMOVA study based on hierarchical cluster and model based approach showed 3 % and 11 % variation between the populations, respectively. Decadal analysis for gene diversity and PIC showed increasing trend from 1940 to 2005, thereafter values for both the parameters showed decreasing trend between years 2006-2013. In contrast to this, allele number demonstrated increasing trend in these varieties released and notified between1940 to 1985, it remained nearly constant during 1986 to 2005 and again showed an increasing trend. Our results demonstrated that the Indian rice varieties harbors huge amount of genetic diversity. However, the trait based improvement program in the last decades forced breeders to rely on few parents, which

Genotype-Phenotype Study of the Middle Gangetic Plain in India Shows Association of rs2470102 with Skin Pigmentation.

PubMed

Mishra, Anshuman; Nizammuddin, Sheikh; Mallick, Chandana Basu; Singh, Sakshi; Prakash, Satya; Siddiqui, Niyamat Ali; Rai, Niraj; Carlus, S Justin; Sudhakar, Digumarthi V S; Tripathi, Vishnu P; Möls, Märt; Kim-Howard, Xana; Dewangan, Hemlata; Mishra, Abhishek; Reddy, Alla G; Roy, Biswajit; Pandey, Krishna; Chaubey, Gyaneshwer; Das, Pradeep; Nath, Swapan K; Singh, Lalji; Thangaraj, Kumarasamy

2017-03-01

Our understanding of the genetics of skin pigmentation has been largely skewed towards populations of European ancestry, imparting less attention to South Asian populations, who behold huge pigmentation diversity. Here, we investigate skin pigmentation variation in a cohort of 1,167 individuals in the Middle Gangetic Plain of the Indian subcontinent. Our data confirm the association of rs1426654 with skin pigmentation among South Asians, consistent with previous studies, and also show association for rs2470102 single nucleotide polymorphism. Our haplotype analyses further help us delineate the haplotype distribution across social categories and skin color. Taken together, our findings suggest that the social structure defined by the caste system in India has a profound influence on the skin pigmentation patterns of the subcontinent. In particular, social category and associated single nucleotide polymorphisms explain about 32% and 6.4%, respectively, of the total phenotypic variance. Phylogeography of the associated single nucleotide polymorphisms studied across 52 diverse populations of the Indian subcontinent shows wide presence of the derived alleles, although their frequencies vary across populations. Our results show that both polymorphisms (rs1426654 and rs2470102) play an important role in the skin pigmentation diversity of South Asians. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

34 CFR 300.21 - Indian and Indian tribe.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false Indian and Indian tribe. 300.21 Section 300.21... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.21 Indian and Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or...

34 CFR 300.21 - Indian and Indian tribe.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false Indian and Indian tribe. 300.21 Section 300.21... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.21 Indian and Indian tribe. (a) Indian means an individual who is a member of an Indian tribe. (b) Indian tribe means any Federal or...

Interethnic Variations and Clinical Features of Spondyloarthropathies in a Middle Eastern Country.

PubMed

Quraishi, Mohammed Kamil; Badsha, Humeira; Khan, Bhavna; Shahzeb, Muhammad; Hegde, Srilakshmi; Mofti, Ayman; Ooi, Kong Kok

2018-01-01

The study aimed to demonstrate the interethnic differences and clinical features of Spondyloarthropathy(SpA) patients in a diverse Middle Eastern Country. A retrospective review of medical records to collect the required data was conducted for SpA patients at two study institutions in the United Arab Emirates. Of 141 SpA patients found, 88 AS(Ankylosing Spondylitis) patients and 53 'other SpA' patients were identified. Males constituted 81% of AS and 55% of 'other SpA' patients. Patients with AS and 'other SpA' had a mean age of symptom onset of 28 and 34 years, respectively.49% and 40% of AS and 'other SpA' patients had a history of Anti-TNF therapy usage. Enthesitis and Uveitis were noted in 16% and 18% of AS patients whilst 53% and 11% in 'other SpA' patients, respectively.Caucasian, Indian Subcontinent and Arabs constituted 93% of our cohort. Mean age of onset of symptoms in the Indian Subcontinent 'other SpA' group was much greater than the other two ethnicities. Duration of symptoms to diagnosis was 3.5 and 4 years in AS and other SpA patients' respectively. HLA-B27 positivity was found in 53%, 80% and 93% of Arab, Indian Subcontinent and Caucasian AS patients, respectively, whilst seen in 50%, 25% and 33% of the same respective ethnicties in 'other SpA' patients. This study on 141 patients is the largest to analyse inter-ethnic variations in SpA patients in the region. Our cohort shows a short delay in diagnosis with a relatively higher Anti-TNF usage.

Epidemic waves of cholera in the last two decades in Mozambique.

PubMed

Langa, José Paulo; Sema, Cynthia; De Deus, Nilsa; Colombo, Mauro Maria; Taviani, Elisa

2015-07-04

Africa is increasingly affected by cholera. In Mozambique, cholera appeared in the early 1970s when the seventh pandemic entered Africa from the Indian subcontinent. In the following decades, several epidemics were registered in the country, the 1997-1999 epidemic being the most extended. Since then, Mozambique has been considered an endemic area for cholera, characterized by yearly outbreaks occurring with a seasonal pattern. At least three pandemic variants are thought to have originated in the Indian subcontinent and spread worldwide at different times. To understand the epidemiology of cholera in Mozambique, whether the disease re-emerges periodically or is imported by different routes of transmission, we investigated clinical V. cholerae O1 isolated during 1997-1999 and 2012-2014 epidemics. By detecting and characterizing seven genetic elements, the mobilome profile of each isolate was obtained. By comparing it to known seventh pandemic reference strains, it was possible to discern among different V. cholerae O1 variants active in the country. During 1997-1999, epidemic strains showed two different genetic profiles, both related to a pandemic clone that originated from India and was reported in other African countries in the 1990s. Isolates from 2012-2014 outbreaks showed a genetic background related to the pandemic strains currently active as the prevalent causative agent of cholera worldwide. Despite cholera being endemic in Mozambique, the epidemiology of the disease in the past 20 years has been strongly influenced by the cholera seventh pandemic waves that originated in the Indian subcontinent.

Genetic diversity analysis of Zingiber Officinale Roscoe by RAPD collected from subcontinent of India.

PubMed

Ashraf, Kamran; Ahmad, Altaf; Chaudhary, Anis; Mujeeb, Mohd; Ahmad, Sayeed; Amir, Mohd; Mallick, N

2014-04-01

The present investigation was undertaken for the assessment of 12 accessions of Zingiber officinale Rosc. collected from subcontinent of India by RAPD markers. DNA was isolated using CTAB method. Thirteen out of twenty primers screened were informative and produced 275 amplification products, among which 261 products (94.90%) were found to be polymorphic. The percentage polymorphism of all 12 accessions ranged from 88.23% to 100%. Most of the RAPD markers studied showed different levels of genetic polymorphism. The data of 275 RAPD bands were used to generate Jaccard's similarity coefficients and to construct a dendrogram by means of UPGMA. Results showed that ginger undergoes genetic variation due to a wide range of ecological conditions. This investigation was an understanding of genetic variation within the accessions. It will also provide an important input into determining resourceful management strategies and help to breeders for ginger improvement program.

Genetic diversity analysis of Zingiber Officinale Roscoe by RAPD collected from subcontinent of India

PubMed Central

Ashraf, Kamran; Ahmad, Altaf; Chaudhary, Anis; Mujeeb, Mohd.; Ahmad, Sayeed; Amir, Mohd.; Mallick, N.

2013-01-01

The present investigation was undertaken for the assessment of 12 accessions of Zingiber officinale Rosc. collected from subcontinent of India by RAPD markers. DNA was isolated using CTAB method. Thirteen out of twenty primers screened were informative and produced 275 amplification products, among which 261 products (94.90%) were found to be polymorphic. The percentage polymorphism of all 12 accessions ranged from 88.23% to 100%. Most of the RAPD markers studied showed different levels of genetic polymorphism. The data of 275 RAPD bands were used to generate Jaccard’s similarity coefficients and to construct a dendrogram by means of UPGMA. Results showed that ginger undergoes genetic variation due to a wide range of ecological conditions. This investigation was an understanding of genetic variation within the accessions. It will also provide an important input into determining resourceful management strategies and help to breeders for ginger improvement program. PMID:24600309

Oral manifestations of human immunodeficiency virus/acquired immunodeficiency syndrome and their correlation to cluster of differentiation lymphocyte count in population of North-East India in highly active antiretroviral therapy era.

PubMed

Nayak, Sarat Kumar; Das, Bijay Kumar; Das, Surya Narayan; Mohapatra, Namita; Nayak, Suryakanti; Bhuyan, Lipsa

2016-01-01

The human immunodeficiency virus (HIV) infection which manifests as acquired immunodeficiency syndrome (AIDS) is a disease involving the defects of the T-lymphocyte arm of the immune system. Certain laboratory parameters such as the cluster of differentiation (CD4) count and clinical parameters have long been used as markers of disease progression. In industrialized countries, many studies show a highly correlation between the incidence of oral lesions and immunosuppression and hence, can be used as a marker of immunosuppression. This might not be applicable to a developing country like India. In this study, efforts have been made to supplement the present knowledge on various aspects of oral manifestations in HIV patients in the Indian subcontinent. To correlate the oral manifestations in HIV/AIDS patients to the level of circulating CD4+ T-lymphocyte count and their effect in anti-retroviral therapy (ART). A total of 104 HIV positive patients were examined for oral lesions. The CD4 count estimated on the same day by fluorescent activated cell sort count machine was then correlated with various oral lesions. Oral manifestations appeared when CD4 count decreased below 500 cells/mm 3 . Moreover, oral lesions found at different stages showed very strong correlation to their respective CD4 count. Furthermore, there was considerable decline in the incidence of oral manifestations in patients undergoing highly active ART. Oral manifestations are highly predictive markers of severe immune deterioration and disease progression in HIV patients.

Simulating Changes in Land-Atmosphere Interactions From Expanding Agriculture and Irrigation in India and the Potential Impacts on the Indian Monsoon.

NASA Astrophysics Data System (ADS)

Douglas, E. M.; Beltran-Przekurat, A.; Niyogi, D.; Pielke, R. A.

2006-05-01

With over 57 million hectares under irrigation in 2002, India has the largest irrigated agricultural area on the planet. Between 80 and 90% of India's water use goes to support irrigated agriculture. The Indian monsoon belt is a home to a large part of the world's population and agriculture is the major land-use activity in the region. Previous results showed that annual vapor fluxes in India have increased by 17% (340 km3) over that which would be expected from a natural (non-agricultural) land cover. Two-thirds of this increase was attributed to irrigated agriculture. The largest increases in vapor and latent heat fluxes occurred where both cropland and irrigated lands were the predominant contemporary land cover classes (particularly northwest and north-central India). Our current study builds upon this work by evaluating possible changes in near-surface energy fluxes and regional atmospheric circulation patterns resulting from the expansion of irrigated agriculture on the Indian sub-continent using a regional atmospheric model RAMS. We investigate three separate land- use scenarios: Scenario 1, with a potential (pre-agricultural) land cover, Scenario 2: the potential land-cover overlain by cropland and Scenario 3: potential land-cover overlain by cropland and irrigated area. We will assess the impact of agricultural land-cover conversion and intensive irrigation on water and energy fluxes between the land and the atmosphere and how these flux changes may affect regional weather patterns. The simulation period covers July 16-20, 2002 which allow us to assess potential impacts of land-cover changes on the onset of the Indian Monsoon.

Indian summer monsoon rainfall variability during 2014 and 2015 and associated Indo-Pacific upper ocean temperature patterns

NASA Astrophysics Data System (ADS)

Kakatkar, Rashmi; Gnanaseelan, C.; Chowdary, J. S.; Parekh, Anant; Deepa, J. S.

2018-02-01

In this study, factors responsible for the deficit Indian Summer Monsoon (ISM) rainfall in 2014 and 2015 and the ability of Indian Institute of Tropical Meteorology-Global Ocean Data Assimilation System (IITM-GODAS) in representing the oceanic features are examined. IITM-GODAS has been used to provide initial conditions for seasonal forecast in India during 2014 and 2015. The years 2014 and 2015 witnessed deficit ISM rainfall but were evolved from two entirely different preconditions over Pacific. This raises concern over the present understanding of the role of Pacific Ocean on ISM variability. Analysis reveals that the mechanisms associated with the rainfall deficit over the Indian Subcontinent are different in the two years. It is found that remote forcing in summer of 2015 due to El Niño is mostly responsible for the deficit monsoon rainfall through changes in Walker circulation and large-scale subsidence. In the case of the summer of 2014, both local circulation with anomalous anticyclone over central India and intrusion of mid-latitude dry winds from north have contributed for the deficit rainfall. In addition to the above, Tropical Indian Ocean (TIO) sea surface temperature (SST) and remote forcing from Pacific Ocean also modulated the ISM rainfall. It is observed that Pacific SST warming has extended westward in 2014, making it a basin scale warming unlike the strong El Niño year 2015. The eastern equatorial Indian Ocean is anomalously warmer than west in summer of 2014, and vice versa in 2015. These differences in SST in both tropical Pacific and TIO have considerable impact on ISM rainfall in 2014 and 2015. The study reveals that initializing coupled forecast models with proper upper ocean temperature over the Indo-Pacific is therefore essential for improved model forecast. It is important to note that the IITM-GODAS which assimilates only array for real-time geostrophic oceanography (ARGO) temperature and salinity profiles could capture most of the

25 CFR 31.3 - Non-Indian pupils in Indian schools.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Non-Indian pupils in Indian schools. 31.3 Section 31.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION FEDERAL SCHOOLS FOR INDIANS § 31.3 Non-Indian pupils in Indian schools. Indian and non-Indian children who are not eligible for...

25 CFR 31.3 - Non-Indian pupils in Indian schools.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Non-Indian pupils in Indian schools. 31.3 Section 31.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION FEDERAL SCHOOLS FOR INDIANS § 31.3 Non-Indian pupils in Indian schools. Indian and non-Indian children who are not eligible for...

25 CFR 31.3 - Non-Indian pupils in Indian schools.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Non-Indian pupils in Indian schools. 31.3 Section 31.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION FEDERAL SCHOOLS FOR INDIANS § 31.3 Non-Indian pupils in Indian schools. Indian and non-Indian children who are not eligible for...

25 CFR 31.3 - Non-Indian pupils in Indian schools.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Non-Indian pupils in Indian schools. 31.3 Section 31.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION FEDERAL SCHOOLS FOR INDIANS § 31.3 Non-Indian pupils in Indian schools. Indian and non-Indian children who are not eligible for...

25 CFR 31.3 - Non-Indian pupils in Indian schools.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Non-Indian pupils in Indian schools. 31.3 Section 31.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION FEDERAL SCHOOLS FOR INDIANS § 31.3 Non-Indian pupils in Indian schools. Indian and non-Indian children who are not eligible for...

Detailed Analysis of Indian Summer Monsoon Rainfall Processes with Modern/High-Quality Satellite Observations

NASA Technical Reports Server (NTRS)

Smith, Eric A.; Kuo, Kwo-Sen; Mehta, Amita V.; Yang, Song

2007-01-01

-annually), (2) time series at these different time scales taken as area-averages over the hierarchy of relevant space scales (Indian sub-Division, Indian sub-continent, and Circumambient Indian Ocean), (3) principal autocorrelation and cross-correlation structures over various monsoon space-time domains, (4) diurnally modulated amplitude-phase properties of rain rates over different monsoon space-time domains, (5) foremost rain rate probability distributions intrinsic to monsoon precipitation, and (6) behavior of extreme events including occurrences of flood and drought episodes throughout the course of inter-annual monsoon processes.

Microsatellite-based phylogeny of Indian domestic goats

PubMed Central

Rout, Pramod K; Joshi, Manjunath B; Mandal, Ajoy; Laloe, D; Singh, Lalji; Thangaraj, Kumarasamy

2008-01-01

Background The domestic goat is one of the important livestock species of India. In the present study we assess genetic diversity of Indian goats using 17 microsatellite markers. Breeds were sampled from their natural habitat, covering different agroclimatic zones. Results The mean number of alleles per locus (NA) ranged from 8.1 in Barbari to 9.7 in Jakhrana goats. The mean expected heterozygosity (He) ranged from 0.739 in Barbari to 0.783 in Jakhrana goats. Deviations from Hardy-Weinberg Equilibrium (HWE) were statistically significant (P < 0.05) for 5 loci breed combinations. The DA measure of genetic distance between pairs of breeds indicated that the lowest distance was between Marwari and Sirohi (0.135). The highest distance was between Pashmina and Black Bengal. An analysis of molecular variance indicated that 6.59% of variance exists among the Indian goat breeds. Both a phylogenetic tree and Principal Component Analysis showed the distribution of breeds in two major clusters with respect to their geographic distribution. Conclusion Our study concludes that Indian goat populations can be classified into distinct genetic groups or breeds based on the microsatellites as well as mtDNA information. PMID:18226239

Alpha-globin gene haplotypes in South American Indians.

PubMed

Zago, M A; Melo Santos, E J; Clegg, J B; Guerreiro, J F; Martinson, J J; Norwich, J; Figueiredo, M S

1995-08-01

The haplotypes of the alpha-globin gene cluster were determined for 99 Indians from the Brazilian Amazon region who belong to 5 tribes: Wayampí, Wayana-Apalaí, Kayapó, Arára, and Yanomámi. Three predominant haplotypes were identified: Ia (present in 38.9% of chromosomes), IIIa (25.8%), and IIe (22.1%). The only alpha-globin gene rearrangement detected was alpha alpha alpha 3.7 I gene triplication associated with haplotype IIIa, found in high frequencies (5.6% and 10.6%) in two tribes and absent in the others. alpha-Globin gene deletions that cause alpha-thalassemia were not seen, supporting the argument that malaria was absent in these populations until recently. The heterogeneous distribution of alpha-globin gene haplotypes and rearrangements among the different tribes differs markedly from the homogeneous distribution of beta-globin gene cluster haplotypes and reflects the action of various genetic mechanisms (genetic drift, founder effect, consanguinity) on small isolated population groups with a complicated history of divergence-fusion events. The alpha-globin gene haplotype distribution has some similarities to distributions observed in Southeast Asian and Pacific Island populations, indicating that these populations have considerable genetic affinities. However, the absence of several features of the alpha-globin gene cluster that are consistently present among the Pacific Islanders suggests that the similarity of haplotypes between Brazilian Indians and people from Polynesia, Micronesia, and Melanesia is more likely to result of ancient common ancestry rather than the consequence of recent direct genetic contribution through immigration.

Three Dimensional Aerosol Climatology over India and the North Indian Ocean

NASA Astrophysics Data System (ADS)

Adams, A.; Zhang, C.

2013-12-01

Numerical models are indispensable tools to study aerosol effects on climate, including both aerosol direct and indirect radiative effects and their role in precipitation. But, agreement among the models has not been achieved, and thus it is not possible to accurately and confidently attain estimates of aerosol effects on climate. The lack of reliable knowledge on global three-dimensional (3D) aerosol climatology has prevented us from assessing the degree to which the disagreement in their aerosol climatic effects may come from differences of aerosol vertical structures in their simulations. To that end, we created a six year, global 3D extinction coefficient dataset for each aerosol species identifiable by the Level 2, Version 3, 5 km Aerosol Profile product from Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) onboard Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) as a tool to improve 3D model representations. Here we describe the 3D structure of aerosol in the Middle East, India, and the Northern Indian Ocean and some of the interesting dynamical features responsible for the vertical structure and external mixing of aerosol species. One interesting feature in the 3D structure during boreal summer is a well-defined EC core located 0 - 10°N, 40°E - 90°E (Somalia across the Indian subcontinent), centered at 3 km. This is controlled by a shallow meridional circulation about the core. Additionally, the Somali Low-Level Jet exists at this location, but is usually located below the core (~850 mb). Another interesting feature is a strong EC core located 0 - 15°N, 60°E - 90°E below 0.5 km. Polluted dust (external mixture of dust and smoke) and marine aerosol are collocated in this area with maximum AODs of ~0.5 and ~0.2 respectively. Due to the wind stress over ocean, collocation of aerosol species, altitude, and lack of transport pathway for polluted dust, it is possible that this is an example of aerosol misclassification by

Leadership Preferences of Indian and Non-Indian Athletes.

ERIC Educational Resources Information Center

Malloy, D. C.; Nilson, R. N.

1991-01-01

Among 86 Indian and non-Indian volleyball competitors, non-Indian players indicated significantly greater preferences for leadership that involved democratic behavior, autocratic behavior, or social support. Indians may adapt their behavior by participating in non-Indian games, without changing their traditional value orientations. Contains 22…

Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A

USDA-ARS?s Scientific Manuscript database

Ethnopharmacological relevance: Ayurveda, an ancient holistic system of health care practiced on the Indian subcontinent, utilizes a number of multi-plant formulations and is considered by many as a potential source for novel treatments, as well as the identification of new drugs. Our aim is to iden...

Designing Collaborative Learning Environments Mediated by Computer Conferencing: Issues and Challenges in the Asian Socio-Cultural Context.

ERIC Educational Resources Information Center

Gunawardena, Charlotte N.

1998-01-01

Explores issues related to the design of collaborative-learning environments mediated by computer conferencing from the perspective of challenges faced in the sociocultural context of the Indian sub-continent. Examines the impact of online features on social cohesiveness, group dynamics, interaction, communication anxiety, and participation.…

Stratigraphic response and mammalian dispersal during initial India-Asia collision: Evidence from the Ghazij Formation, Balochistan, Pakistan

NASA Astrophysics Data System (ADS)

Clyde, William C.; Khan, Intizar H.; Gingerich, Philip D.

2003-12-01

Initial continental collision between India and Asia is thought to have caused significant changes to global climate and biota, yet its timing and biogeographic consequences are uncertain. Structural and geophysical evidence indicates initial collision during the early Paleogene, but sedimentary evidence of this has been controversial owing to the intense deformation and metamorphism along the suture zone. Modern orders of mammals that appeared abruptly on northern continents coincident with the global warming event marking the Paleocene-Eocene boundary are hypothesized to have originated on the Indian subcontinent, but no relevant paleontological information has been available to test this idea. Here we present new paleomagnetic, sedimentologic, and paleontologic evidence to show that the lower Eocene Ghazij Formation of western Pakistan records continental sedimentation and mammalian dispersal associated with initial India-Asia collision. Our results are consistent with the initial collision occurring near the Paleocene-Eocene boundary, but modern orders of mammals appeared later in Indo-Pakistan and thus did not likely originate on the Indian subcontinent.

Studies of the Correlation Between Ionospheric Anomalies and Seismic Activities in the Indian Subcontinent

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sasmal, S.; Chakrabarti, S. K.; S. N. Bose National Centre for Basic Sciences, JD Block, Salt-Lake Kolkata-70098

2010-10-20

The VLF (Very Low Frequency) signals are long thought to give away important information about the Lithosphere-Ionosphere coupling. It is recently established that the ionosphere may be perturbed due to seismic activities. The effects of this perturbation can be detected through the VLF wave amplitude. There are several methods to find this correlations and these methods can be used for the prediction of these seismic events. In this paper, first we present a brief history of the use of VLF propagation method for the study of seismo-ionospheric correlations. Then we present different methods proposed by us to find out themore » seismo-ionospheric correlations. At the Indian Centre for Space Physics, Kolkata we have been monitoring the VTX station at Vijayanarayanam from 2002. In the initial stage, we received 17 kHz signal and latter we received 18.2 kHz signal. In this paper, first we present the results for the 17 kHz signal during Sumatra earthquake in 2004 obtained from the terminator time analysis method. Then we present much detailed and statistical analysis using some new methods and present the results for 18.2 kHz signal. In order to establish the correlation between the ionospheric activities and the earthquakes, we need to understand what are the reference signals throughout the year. We present the result of the sunrise and sunset terminators for the 18.2 kHz signal as a function of the day of the year for a period of four years, viz, 2005 to 2008 when the solar activity was very low. In this case, the signal would primarily be affected by the Sun due to normal sunrise and sunset effects. Any deviation from this standardized calibration curve would point to influences by terrestrial (such as earthquakes) and extra-terrestrial (such as solar activities and other high energy phenomena). We present examples of deviations which occur in a period of sixteen months and show that the correlations with seismic events is significant and typically the highest

Application of Factor Analysis on the Financial Ratios of Indian Cement Industry and Validation of the Results by Cluster Analysis

NASA Astrophysics Data System (ADS)

De, Anupam; Bandyopadhyay, Gautam; Chakraborty, B. N.

2010-10-01

Financial ratio analysis is an important and commonly used tool in analyzing financial health of a firm. Quite a large number of financial ratios, which can be categorized in different groups, are used for this analysis. However, to reduce number of ratios to be used for financial analysis and regrouping them into different groups on basis of empirical evidence, Factor Analysis technique is being used successfully by different researches during the last three decades. In this study Factor Analysis has been applied over audited financial data of Indian cement companies for a period of 10 years. The sample companies are listed on the Stock Exchange India (BSE and NSE). Factor Analysis, conducted over 44 variables (financial ratios) grouped in 7 categories, resulted in 11 underlying categories (factors). Each factor is named in an appropriate manner considering the factor loads and constituent variables (ratios). Representative ratios are identified for each such factor. To validate the results of Factor Analysis and to reach final conclusion regarding the representative ratios, Cluster Analysis had been performed.

Molecular characterization of Indian rabies virus isolates by partial sequencing of nucleoprotein (N) and phosphoprotein (P) genes.

PubMed

Reddy, G B Manjunatha; Singh, R; Singh, R P; Singh, K P; Gupta, P K; Mahadevan, Anita; Desai, Anita; Shankar, S K; Ramakrishnan, M A; Verma, Rishendra

2011-08-01

Rabies is endemic and an important zoonosis in India. There are very few reports available on molecular epidemiology of rabies virus of Indian origin. In this study to know the dynamics of rabies virus, a total of 41 rabies positive brain samples from dogs, cats, domestic animals, wildlife, and humans from 11 states were subjected to RT-PCR amplification of N gene between nucleotide N521-N1262 (742 bp) and P gene between nucleotide P239-P750 (512 bp). The N gene could be amplified from 30, while P gene from 41 samples, using specific sets of primers. The N gene-based phylogenetic analysis indicated that all Indian virus isolates are genetically closely related with a single cluster under arctic/arctic-like viruses. However, two distinct clusters were realized in P gene-based phylogeny viz., Rabies virus isolates of Punjab and Rabies virus isolates of remaining parts of India (other than Punjab). All the Indian rabies virus isolates were closely related to geography (>95% homology), but not to host species.

Early forecasting of Indian Summer Monsoon: case study 2016

NASA Astrophysics Data System (ADS)

Surovyatkina, Elena; Stolbova, Veronika; Kurths, Jurgen

2017-04-01

The prior knowledge of dates of onset and withdrawal of monsoon is of vital importance for the population of the Indian subcontinent. In May 2016 before monsoon season, India recorded its highest-ever temperature of 51C. Hot waves have decimated crops, killed livestock and left 330 million people without enough water. At the end of monsoon season the floods in Indian this year have also broken previous records. Severe and devastating rainfall poured down, triggering dams spilling and floods. Such extreme conditions pose the vital questions such as: When will the monsoon come? When will the monsoon withdraw? More lead time in monsoon forecast warning is crucial for taking appropriate decisions at various levels - from the farmer's field (e.g. plowing day, seeding) to the central government (e.g. managing water and energy resources, food procurement policies). The Indian Meteorological Department issues forecasts of onset of monsoon for Kerala state in South India on May 15-th. It does not give such predictions for the other 28 states of the country. Our study concerns the central part of India. We made the monsoon forecast using our recently developed method which focuses on Tipping elements of the Indian monsoon [1]. Our prediction relies on observations of near-surface air temperature and relative humidity from both the ERA-40 and NCEP/NCAR reanalyses. We performed both of our forecasts for the onset and withdrawal of monsoon for the central part of India, the Eastern Ghats (20N,80E). We predicted the monsoon arrival to the Eastern Ghats (20N,80E) on the 13th of June with a deviation of +/-4 days. The prediction was made on May 6-th, 2016 [2], that is 40 days in advance of the date of the forecast. The actual monsoon arrival was June 17-th. In this day near-surface air temperature and relative humidity overcame the critical values and the monsoon season started, that was confirmed by observations of meteorological stations located around the EG-region. We

Spatio-temporal interaction between absorbing aerosols and temperature: Correlation and causality based approach

NASA Astrophysics Data System (ADS)

Dave, P.; Bhushan, M.; Venkataraman, C.

2016-12-01

Indian subcontinent, in particular, the Indo-gangetic plain (IGP) has witnessed large temperature anomalies (Ratnam et al., 2016) along with high emission of absorbing aerosols (AA) (Gazala, et al., 2005). The anomalous high temperature observed over this region may bear a relationship with high AA emissions. Different studies have been conducted to understand AA and temperature relationships (Turco et al., 1983; Hansen et al., 1997, 2005; Seinfeld 2008; Ramanathan et al. 2010b; Ban-Weiss et al., 2012). It was found that when the AA was injected in the lower- mid troposphere the surface air temperature increases while injection of AA at higher troposphere-lower stratosphere surface temperature decreases. These studies used simulation based results to establish link between AA and temperature (Hansen et al., 1997, 2005; Ban-Weiss et al., 2012). The current work focuses on identifying the causal influence of AA on temperature using observational and re-analysis data over Indian subcontinent using cross correlation (CCs) and Granger causality (GC) (Granger, 1969). Aerosol index (AI) from TOMS-OMI was used as index for AA while ERA-interim reanalysis data was used for temperature at varying altitude. Period of study was March-April-May-June (MAMJ) for years 1979-2015. CCs were calculated for all the atmospheric layers. In each layer nearby and distant pixels (>500 kms) with high CCs were identified using clustering technique. It was found that that AI and Temperature shows statistically significant cross-correlations for co-located and distant pixels and more prominently over IGP. The CCs fades away with higher altitudes. CCs analysis was followed by GC analysis to identify the lag over which AI can influence the Temperature. GC also supported the findings of CCs analysis. It is an early attempt to link persisting large temperature anomalies with absorbing aerosols and may help in identifying the role of absorbing aerosol in causing heat waves.

Uncovering the sources of DNA found on the Turin Shroud

PubMed Central

Barcaccia, Gianni; Galla, Giulio; Achilli, Alessandro; Olivieri, Anna; Torroni, Antonio

2015-01-01

The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago. Here, we report the main findings from the analysis of genomic DNA extracted from dust particles vacuumed from parts of the body image and the lateral edge used for radiocarbon dating. Several plant taxa native to the Mediterranean area were identified as well as species with a primary center of origin in Asia, the Middle East or the Americas but introduced in a historical interval later than the Medieval period. Regarding human mitogenome lineages, our analyses detected sequences from multiple subjects of different ethnic origins, which clustered into a number of Western Eurasian haplogroups, including some known to be typical of Western Europe, the Near East, the Arabian Peninsula and the Indian sub-continent. Such diversity does not exclude a Medieval origin in Europe but it would be also compatible with the historic path followed by the Turin Shroud during its presumed journey from the Near East. Furthermore, the results raise the possibility of an Indian manufacture of the linen cloth. PMID:26434580

Foot-and-mouth disease virus serotype O phylodynamics: genetic variability associated with epidemiological factors in Pakistan

USDA-ARS?s Scientific Manuscript database

One of the most challenging aspects of foot-and-mouth disease (FMD) control is the high genetic variability of the FMD virus (FMDV). In endemic settings such as the Indian subcontinent, this variability has resulted in the emergence of pandemic strains that have spread widely and caused devastating ...

Higher iron pearl millet (Pennisetum glaucum L.) provides more absorbable iron that is limited by increased polyphenolic content

USDA-ARS?s Scientific Manuscript database

Background: Our objective was to compare the capacity of iron (Fe) biofortified and standard pearl millet (Pennisetum glaucum L.) to deliver Fe for hemoglobin (Hb) synthesis. Pearl millet is the most widely grown type of millet. It is common primarily in West Africa and the Indian subcontinent, and ...

Monopelopia mongpuense sp. n., a phytotelmata midge from sub-Himalayan region of India (Diptera: Chironomidae: Tanypodinae).

PubMed

Paul, Nilotpol; Hazra, Niladri; Mazumdar, Abhijit

2014-05-23

Immature and adult stages of Monopelopia mongpuense sp. n. from phytotelmata of Cedrus deodara (Lamb.) in Darjeeling are described along with biological notes. Key to the adult males of all species of the genus Monopelopia Fittkau is also presented. This genus is recorded for the first from Indian subcontinent.

Spatial patterns in vegetation fires in the Indian region.

PubMed

Vadrevu, Krishna Prasad; Badarinath, K V S; Anuradha, Eaturu

2008-12-01

In this study, we used fire count datasets derived from Along Track Scanning Radiometer (ATSR) satellite to characterize spatial patterns in fire occurrences across highly diverse geographical, vegetation and topographic gradients in the Indian region. For characterizing the spatial patterns of fire occurrences, observed fire point patterns were tested against the hypothesis of a complete spatial random (CSR) pattern using three different techniques, the quadrat analysis, nearest neighbor analysis and Ripley's K function. Hierarchical nearest neighboring technique was used to depict the 'hotspots' of fire incidents. Of the different states, highest fire counts were recorded in Madhya Pradesh (14.77%) followed by Gujarat (10.86%), Maharastra (9.92%), Mizoram (7.66%), Jharkhand (6.41%), etc. With respect to the vegetation categories, highest number of fires were recorded in agricultural regions (40.26%) followed by tropical moist deciduous vegetation (12.72), dry deciduous vegetation (11.40%), abandoned slash and burn secondary forests (9.04%), tropical montane forests (8.07%) followed by others. Analysis of fire counts based on elevation and slope range suggested that maximum number of fires occurred in low and medium elevation types and in very low to low-slope categories. Results from three different spatial techniques for spatial pattern suggested clustered pattern in fire events compared to CSR. Most importantly, results from Ripley's K statistic suggested that fire events are highly clustered at a lag-distance of 125 miles. Hierarchical nearest neighboring clustering technique identified significant clusters of fire 'hotspots' in different states in northeast and central India. The implications of these results in fire management and mitigation were discussed. Also, this study highlights the potential of spatial point pattern statistics in environmental monitoring and assessment studies with special reference to fire events in the Indian region.

Planetary Boundary Layer Patterns, Height Variability and their Controls over the Indian Subcontinent with respect to Monsoon

NASA Astrophysics Data System (ADS)

Sathyanadh, A.; Karipot, A.; Prabhakaran, T.

2016-12-01

Planetary boundary layer (PBL) height and its controlling factors undergo large variations at different spatio-temporal scales over land regions. In the present study, Modern Era Retrospective analysis for Research and Applications (MERRA) data products are used to investigate variations of PBL height and its controls in relation to different phases of Indian monsoon. MERRA PBL height validations carried out against those estimated from radiosonde and Global Positioning System Radio Occultation atmospheric profiles revealed fairly good agreement. Different PBL patterns are identified in terms of maximum height, its time of occurrence and growth rate, and they vary with respect to geographical locations, terrain characteristics and monsoon circulation. The pre-monsoon boundary layers are the deepest over the region, often exceeding 4 km and grow at a rate of approximately 400 m hr-1. Large nocturnal BL depths, possibly related to weakly convective residual layers, are another feature noted during dry conditions. Monsoon BLs are generally shallower, except where rainfall is scanty. The break-monsoon periods have slightly deeper BLs than the active monsoon phase. The controlling factors for the observed boundary layer behaviour are investigated using supplementary MERRA datasets. Evaporative fraction is found to have dominant control on the PBL height varying with seasons and regions. The characteristics and controls of wet and dry boundary layer regimes over inland and coastal locations are different. The fractional diffusion (ratio of non-local and total diffusion) coefficient analyses indicated that enhanced entrainment during monsoon contributes to reduction in PBLH unlike in the dry period. The relationship between controls and PBLH are better defined over inland than coastal regions. The wavelet cross spectral analysis revealed temporal variations in dominant contributions from the controlling factors at different periodicities during the course of the year.

Interethnic Variations and Clinical Features of Spondyloarthropathies in a Middle Eastern Country

PubMed Central

Quraishi, Mohammed Kamil; Badsha, Humeira; Khan, Bhavna; Shahzeb, Muhammad; Hegde, Srilakshmi; Mofti, Ayman; Ooi, Kong Kok

2018-01-01

Objectives: The study aimed to demonstrate the interethnic differences and clinical features of Spondyloarthropathy(SpA) patients in a diverse Middle Eastern Country. Methods: A retrospective review of medical records to collect the required data was conducted for SpA patients at two study institutions in the United Arab Emirates. Results: Of 141 SpA patients found, 88 AS(Ankylosing Spondylitis) patients and 53 ‘other SpA’ patients were identified. Males constituted 81% of AS and 55% of ‘other SpA’ patients. Patients with AS and ‘other SpA’ had a mean age of symptom onset of 28 and 34 years, respectively. 49% and 40% of AS and ‘other SpA’ patients had a history of Anti-TNF therapy usage. Enthesitis and Uveitis were noted in 16% and 18% of AS patients whilst 53% and 11% in ‘other SpA’ patients, respectively. Caucasian, Indian Subcontinent and Arabs constituted 93% of our cohort. Mean age of onset of symptoms in the Indian Subcontinent ‘other SpA’ group was much greater than the other two ethnicities. Duration of symptoms to diagnosis was 3.5 and 4 years in AS and other SpA patients' respectively. HLA-B27 positivity was found in 53%, 80% and 93% of Arab, Indian Subcontinent and Caucasian AS patients, respectively, whilst seen in 50%, 25% and 33% of the same respective ethnicties in ‘other SpA’ patients. Conclusion: This study on 141 patients is the largest to analyse inter-ethnic variations in SpA patients in the region. Our cohort shows a short delay in diagnosis with a relatively higher Anti-TNF usage. PMID:29456775

Persistence of lower birth weight in second generation South Asian babies born in the United Kingdom.

PubMed

Margetts, B M; Mohd Yusof, S; Al Dallal, Z; Jackson, A A

2002-09-01

To assess differences in birth weight between all first and second generation South Asian babies born in Southampton, and trends since 1957. Retrospective, cohort study. Birth records for babies born in Southampton from 1957 to 1996 were searched to identify all babies born of South Asian origin (including from the Indian subcontinent, East Africa, and elsewhere). All information recorded in the birth record about the mother and baby was extracted. 2395 full term (>37 weeks; mean birth weight 3110; 95%CI 3092 to 3129) singleton births were identified. Detailed analysis was restricted to mothers either born in the Indian subcontinent (India, Pakistan, or Bangladesh (1435)) or United Kingdom (283). Mean birth weight and % low birth weight (<2500 g) were 3133 g (95%CI 3108 to 3157) and 7.5%, for first generation babies and 3046 g (2992 to 3099) and 11.7% for second generation babies. There was no trend over time to increased average birth weight in either first or second generation babies. Adjusting for other factors that were statistically significantly related to birth weight (gender, gestational age, mother's age, maternal weight at 15 weeks, parity, and mother's ethnic group) did not alter the trends. For that group in the UK who derive from the Indian subcontinent, average birth weight is significantly less than the national average. There has not been any increase in the average birth weight over the past 40 years, and the birth weight of babies of women who were born in the UK are no greater. The persistence of lower than desirable birth weight may result long term in higher than average rates of diabetes and heart disease in these groups.

Sequence homology and structural analysis of plasmepsin 4 isolated from Indian Plasmodium vivax isolates.

PubMed

Rawat, Manmeet; Vijay, Sonam; Gupta, Yash; Dixit, Rajnikant; Tiwari, P K; Sharma, Arun

2011-07-01

Plasmodium vivax malaria is a globally widespread disease responsible for 50% of human malaria cases in Central and South America, South East Asia and Indian subcontinent. The rising severity of the disease and emerging resistance of the parasite has emphasized the need for the search of novel therapeutic targets to combat P. vivax malaria. Plasmepsin 4 (PM4) a food vacuole aspartic protease is essential in parasite functions and viability such as initiating hemoglobin digestion and processing of proteins and is being looked upon as potential drug target. Although the plasmepsins of Plasmodium falciparum have been extensively studied, the plasmepsins of P. vivax are not well characterized. This is the first report detailing complete PM4 gene analysis from Indian P. vivax isolates. Blast results of sequences of P. vivax plasmepsin 4 (PvPM4) shows 100% homology among isolates of P. vivax collected from different geographical regions of India. All of the seven Indian isolates did not contain intron within the coding region. Interestingly, PvPM4 sequence analysis showed a very high degree of homology with all other sequences of Plasmodium species available in the genebank. Our results strongly suggest that PvPM4 are highly conserved except a small number of amino acid substitutions that did not modify key motifs at active site formation for the function or the structure of the enzymes. Furthermore, our study shows that PvPM4 occupies unique phylogenetic status within Plasmodium group and sufficiently differ from the most closely related human aspartic protease, cathepsin D. The analysis of 3D model of PM4 showed a typical aspartic protease structure with bi-lobed, compact and distinct peptide binding cleft in both P. vivax and P. falciparum. In order to validate appropriate use of PM4 as potential anti-malarial drug target, studies on genetic and structural variations among P. vivax plasmepsins (PvPMs) from different geographical regions are of utmost importance for

Water vapour variability during Indian monsoon over Trivandrum observed using Microwave Radiometer and GPS

NASA Astrophysics Data System (ADS)

Raju, Suresh C.; Krishna Moorthy, K.; Ramachandran Pillai, Renju; Uma, K. N.; Saha, Korak

2012-07-01

The Indian summer monsoon is a highly regular synoptic event, providing most of the annual rainfall received over the sub-continent. Trivandrum, at the southwestern tip of Indian peninsula, is considered as the gate way of Indian monsoon, with its climatological onset on June 01. During this season, the region, experiences large seasonal variation in water vapor, rain fall and wind (speed and direction) in the troposphere. The variability in water vapor and wind information are the vital parameters in forecasting the onset of monsoon. This study focuses on water vapor measurements over the tropical coastal station Trivandrum (8.5oN & 76.9oE) using microwave techniques and the analyses with an effort to link the seasonal variability of water vapor with the onset of monsoon. At Trivandrum a hyper-spectral microwave radiometer profiler (MRP) and a Triple-frequency global positioning system receiver (GPS) have been in regular operation since April 2010. A station-dependent simple empirical relation suitable for the equatorial atmospheric condition is formulated to map the nonhydrostatic component of GPS tropospheric delay to the PWV, based on the columnar water vapor estimated from the multi-year daily radiosonde ascends from Trivandrum. A trained artificial neural network (ANN) with climatological atmospheric data of Trivandrum, is employed to derive the water vapor from the MRP brightness temperature measurements. The accuracy, reliability and consistency of PWV measurements over the tropical coastal station from these two independent instruments are assessed by comparing PWV derived from MRP and GPS measurements which resulted an rms deviation of <1.2mm (with correlation coefficient of ~0.98). This confirms the PWV derived over Trivandrum from microwave measurements are accurate even during the monsoon period in the presence of clouds and rain. PWV from microwave radiometer measurements for more than two years are used to study the water vapour variability during

Multiple begomoviruses found associated with cotton leaf curl disease in Pakistan in early 1990 are back in cultivated cotton

USDA-ARS?s Scientific Manuscript database

The first epidemic of cotton leaf curl disease (CLCuD) in the early 1990’s on the Indian subcontinent was associated with several distinct begomoviruses along with a disease-specific betasatellite. Resistant cotton varieties were introduced in the late 1990’s, but resistance was broken in early 2000...

Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV-116E in Indian infants.

PubMed

Appaiahgari, Mohan Babu; Glass, Roger; Singh, Shakti; Taneja, Sunita; Rongsen-Chandola, Temsunaro; Bhandari, Nita; Mishra, Sukhdev; Vrati, Sudhanshu

2014-02-03

The lower immune response and efficacy of live oral rotavirus (RV) vaccines tested in developing countries may be due in part to high levels of pre-existing RV antibodies transferred to the infant from mother via the placenta. The candidate RV vaccine strain 116E was isolated from a newborn indicating that it might grow well even in the presence of this transplacental rotavirus antibody. Since the immune response to this vaccine among infants in the Indian subcontinent has been greater than that of the commercially licensed vaccines, we questioned whether this might be due to the ability of RV 116E to grow well in infants despite the presence of maternal RV antibody. To this end, we tested pre-immunization sera from Indian infants enrolled in a phase Ia/IIb trial of candidate RV vaccine ORV-116E for transplacental RV IgG to see whether it affected the immune responses and seroconversion to the vaccine. We found that the high titers of transplacental RV IgG diminished the immune responses of infants to ORV-116E vaccine. However, the vaccine was able to overcome the inhibitory effect of this RV IgG in a dose-dependent manner. This report clearly demonstrates the interference of maternal antibody on RV vaccine immunogenicity in infants in a field study as well as the ability of ORV-116E to overcome this interference when used at a higher dose. Copyright © 2013. Published by Elsevier Ltd.

The complete genome sequence of a south Indian isolate of Rice tungro spherical virus reveals evidence of genetic recombination between distinct isolates.

PubMed

Sailaja, B; Anjum, Najreen; Patil, Yogesh K; Agarwal, Surekha; Malathi, P; Krishnaveni, D; Balachandran, S M; Viraktamath, B C; Mangrauthia, Satendra K

2013-12-01

In this study, complete genome of a south Indian isolate of Rice tungro spherical virus (RTSV) from Andhra Pradesh (AP) was sequenced, and the predicted amino acid sequence was analysed. The RTSV RNA genome consists of 12,171 nt without the poly(A) tail, encoding a putative typical polyprotein of 3,470 amino acids. Furthermore, cleavage sites and sequence motifs of the polyprotein were predicted. Multiple alignment with other RTSV isolates showed a nucleotide sequence identity of 95% to east Indian isolates and 90% to Philippines isolates. A phylogenetic tree based on complete genome sequence showed that Indian isolates clustered together, while Vt6 and PhilA isolates of Philippines formed two separate clusters. Twelve recombination events were detected in RNA genome of RTSV using the Recombination Detection Program version 3. Recombination analysis suggested significant role of 5' end and central region of genome in virus evolution. Further, AP and Odisha isolates appeared as important RTSV isolates involved in diversification of this virus in India through recombination phenomenon. The new addition of complete genome of first south Indian isolate provided an opportunity to establish the molecular evolution of RTSV through recombination analysis and phylogenetic relationship.

Indo-European and the Nostratic Hypothesis: History of Research, Current Trends, and Future Prospects.

ERIC Educational Resources Information Center

Bomhard, Allan R.

A discussion of Indo-European languages proposes that this language family is not genetically isolated but is distantly related to certain other language families of northern and central Eurasia, the Indian subcontinent, and the ancient Near East. The history of research into this macrofamily of languages, termed Nostratic, is reviewed, with notes…

Role and movement of nilgai antelope, Boselaphus tragocamelus, in the epizootiology of cattle fever ticks (Acari: Ixodidae) in re-infestations along the Texas/Mexico border in south Texas

USDA-ARS?s Scientific Manuscript database

Nilgai antelope are the largest Asian antelope and are originally endemic to the Indian subcontinent. Nilgai were introduced into Texas in the 1940s for hunting purposes and are now the most abundant free-ranging ungulate in south Texas with population estimates in the early 1990s of more than 36,0...

23 CFR 230.305 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... of the original peoples of Europe, North Africa, the Middle East, or the Indian Subcontinent. (2) The... Islands. This area includes, for example, China, Japan, Korea, the Philippine Islands, and Samoa. (5) The... North America. (e) State means any of the 50 States of the United States, the District of Columbia, the...

23 CFR 230.305 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... of the original peoples of Europe, North Africa, the Middle East, or the Indian Subcontinent. (2) The... Islands. This area includes, for example, China, Japan, Korea, the Philippine Islands, and Samoa. (5) The... North America. (e) State means any of the 50 States of the United States, the District of Columbia, the...

23 CFR 230.305 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... of the original peoples of Europe, North Africa, the Middle East, or the Indian Subcontinent. (2) The... Islands. This area includes, for example, China, Japan, Korea, the Philippine Islands, and Samoa. (5) The... North America. (e) State means any of the 50 States of the United States, the District of Columbia, the...

23 CFR 230.305 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... of the original peoples of Europe, North Africa, the Middle East, or the Indian Subcontinent. (2) The... Islands. This area includes, for example, China, Japan, Korea, the Philippine Islands, and Samoa. (5) The... North America. (e) State means any of the 50 States of the United States, the District of Columbia, the...

Emergence of a Latent Indian Cassava Mosaic Virus from Cassava Which Recovered from Infection by a Non-Persistent Sri Lankan Cassava Mosaic Virus

PubMed Central

Karthikeyan, Chockalingam; Patil, Basavaprabhu L.; Borah, Basanta K.; Resmi, Thulasi R.; Turco, Silvia; Pooggin, Mikhail M.; Hohn, Thomas; Veluthambi, Karuppannan

2016-01-01

The major threat for cassava cultivation on the Indian subcontinent is cassava mosaic disease (CMD) caused by cassava mosaic geminiviruses which are bipartite begomoviruses with DNA A and DNA B components. Indian cassava mosaic virus (ICMV) and Sri Lankan cassava mosaic virus (SLCMV) cause CMD in India. Two isolates of SLCMV infected the cassava cultivar Sengutchi in the fields near Malappuram and Thiruvananthapuram cities of Kerala State, India. The Malappuram isolate was persistent when maintained in the Madurai Kamaraj University (MKU, Madurai, Tamil Nadu, India) greenhouse, whereas the Thiruvananthapuram isolate did not persist. The recovered cassava plants with the non-persistent SLCMV, which were maintained vegetative in quarantine in the University of Basel (Basel, Switzerland) greenhouse, displayed re-emergence of CMD after a six-month period. Interestingly, these plants did not carry SLCMV but carried ICMV. It is interpreted that the field-collected, SLCMV-infected cassava plants were co-infected with low levels of ICMV. The loss of SLCMV in recovered cassava plants, under greenhouse conditions, then facilitated the re-emergence of ICMV. The partial dimer clones of the persistent and non-persistent isolates of SLCMV and the re-emerged isolate of ICMV were infective in Nicotiana benthamiana upon agroinoculation. Studies on pseudo-recombination between SLCMV and ICMV in N. benthamiana provided evidence for trans-replication of ICMV DNA B by SLCMV DNA A. PMID:27690084

Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans

PubMed Central

Metspalu, Mait; Kivisild, Toomas; Metspalu, Ene; Parik, Jüri; Hudjashov, Georgi; Kaldma, Katrin; Serk, Piia; Karmin, Monika; Behar, Doron M; Gilbert, M Thomas P; Endicott, Phillip; Mastana, Sarabjit; Papiha, Surinder S; Skorecki, Karl; Torroni, Antonio; Villems, Richard

2004-01-01

Background Recent advances in the understanding of the maternal and paternal heritage of south and southwest Asian populations have highlighted their role in the colonization of Eurasia by anatomically modern humans. Further understanding requires a deeper insight into the topology of the branches of the Indian mtDNA phylogenetic tree, which should be contextualized within the phylogeography of the neighboring regional mtDNA variation. Accordingly, we have analyzed mtDNA control and coding region variation in 796 Indian (including both tribal and caste populations from different parts of India) and 436 Iranian mtDNAs. The results were integrated and analyzed together with published data from South, Southeast Asia and West Eurasia. Results Four new Indian-specific haplogroup M sub-clades were defined. These, in combination with two previously described haplogroups, encompass approximately one third of the haplogroup M mtDNAs in India. Their phylogeography and spread among different linguistic phyla and social strata was investigated in detail. Furthermore, the analysis of the Iranian mtDNA pool revealed patterns of limited reciprocal gene flow between Iran and the Indian sub-continent and allowed the identification of different assemblies of shared mtDNA sub-clades. Conclusions Since the initial peopling of South and West Asia by anatomically modern humans, when this region may well have provided the initial settlers who colonized much of the rest of Eurasia, the gene flow in and out of India of the maternally transmitted mtDNA has been surprisingly limited. Specifically, our analysis of the mtDNA haplogroups, which are shared between Indian and Iranian populations and exhibit coalescence ages corresponding to around the early Upper Paleolithic, indicates that they are present in India largely as Indian-specific sub-lineages. In contrast, other ancient Indian-specific variants of M and R are very rare outside the sub-continent. PMID:15339343

Simulation of Aerosol Transport and Radiative Effects In Lmd-gcm During Indoex-ifp 1999

NASA Astrophysics Data System (ADS)

Reddy, M. S.; Boucher, O.; Léon, J.-F.; Venkataraman, C.; Pham, M.

During the January-March 1999, an international collaborative field experiment, In- dian Ocean Experiment (INDOEX) was carried out to understand the anthropogenic aerosol effects on radiative forcing (Ramanathan, 2001). In the present work we sim- ulated the cycle of the multi-component aerosol (sulphate, black carbon, organic car- bon, dust, sea-salt and fly-ash) in the Laboratoire de Météorologie Dynamique General Circulation Model (LMD GCM) and estimated the consequent radiative forcing. Sim- ulations are carried out in the zoomed version of the model focusing on the Indian sub- continent and Indian Ocean regions, for January-April 1999. To account correctly for the aerosol emissions in the source regions (Indian subcontinent) we have integrated newly developed SO2 and aerosol emission inventory for India for 1999 (Reddy and Venkataraman, 2002a and b) into the global emission data set input to model. Model performance is evaluated by comparing the simulated aerosol concentration fields against measurements over continental and oceanic stations. Model predicted concentrations agree well in the oceanic stations but are in the lower end of mea- surements in the continental stations. A large plume of sulphate and other aerosols ex- tended from the Indian sub-continent into the Indian Ocean, from surface and elevated flows, extending down to 5S in the pristine southern Indian Ocean. Predicted spec- trally resolved aerosol optical depths (AOD) will be compared with sun-photometer measurements in the region. We also present a comparison of model predicted aerosol optical depths with satellite (Meteosat) derived AOD for the same period. An assess- ment of the multi-component aerosol radiative forcing will be made and results will be discussed in the context of the possible climate effects over the region. Finally, the regional source contributions to sulphate and carbonaceous aerosol loadings in the Indian Ocean will be presented.

Vitamin D Deficiency in India: Prevalence, Causalities and Interventions

PubMed Central

G, Ritu; Gupta, Ajay

2014-01-01

Vitamin D deficiency prevails in epidemic proportions all over the Indian subcontinent, with a prevalence of 70%–100% in the general population. In India, widely consumed food items such as dairy products are rarely fortified with vitamin D. Indian socioreligious and cultural practices do not facilitate adequate sun exposure, thereby negating potential benefits of plentiful sunshine. Consequently, subclinical vitamin D deficiency is highly prevalent in both urban and rural settings, and across all socioeconomic and geographic strata. Vitamin D deficiency is likely to play an important role in the very high prevalence of rickets, osteoporosis, cardiovascular diseases, diabetes, cancer and infections such as tuberculosis in India. Fortification of staple foods with vitamin D is the most viable population based strategy to achieve vitamin D sufficiency. Unfortunately, even in advanced countries like USA and Canada, food fortification strategies with vitamin D have been only partially effective and have largely failed to attain vitamin D sufficiency. This article reviews the status of vitamin D nutrition in the Indian subcontinent and also the underlying causes for this epidemic. Implementation of population based educational and interventional strategies to combat this scourge require recognition of vitamin D deficiency as a public health problem by the governing bodies so that healthcare funds can be allocated appropriately. PMID:24566435

Patterns and Impact of Comorbidity and Multimorbidity among Community-Resident American Indian Elders

ERIC Educational Resources Information Center

John, Robert; Kerby, Dave S.; Hennessy, Catherine Hagan

2003-01-01

Purpose: The purpose of this study is to suggest a new approach to identifying patterns of comorbidity and multimorbidity. Design and Methods: A random sample of 1,039 rural community-resident American Indian elders aged 60 years and older was surveyed. Comorbidity was investigated with four standard approaches, and with cluster analysis. Results:…

[Dengue fever in the Reunion Island and in South Western islands of the Indian Ocean].

PubMed

D'Ortenzio, E; Balleydier, E; Baville, M; Filleul, L; Renault, P

2011-09-01

South Western islands of the Indian Ocean are permanently threatened by dengue fever outbreaks. On the Reunion Island, two dengue outbreaks were biologically documented (1977-1978 and 2004). And since July 2004 there has been an inter-epidemic period for the island with sporadic cases and clusters. Between January 1, 2007 and October 5, 2009, the epidemiologic surveillance system detected five confirmed autochthonous cases, five confirmed imported cases (South-East Asia), and 71 probable cases. All the five autochthonous confirmed cases occurred in Saint-Louis during two consecutive clusters. In other South Western islands of the Indian Ocean, several dengue fever outbreaks have been reported. Importation of dengue virus from South-East Asia is a major risk for a new outbreak on the island. The introduction of a new serotype could lead to the emergence of new and severe clinical forms, including dengue hemorrhagic fever. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

Racial differences in the fasting lipid profile of healthy Malaysians.

PubMed

Zaraihan, S; Azman, A B; Tariq, A R

1994-12-01

The fasting lipid profile of a sample of Malays, Chinese and Indians in Peninsular Malaysia was studied to see whether these might explain differences in the rate of coronary heart disease mortality amongst the three ethnic groups. Fifty healthy subjects were studied from each of the three groups. They were matched for age, body mass index, gender and smoking habits, if any. The total cholesterol/HDL-cholesterol ratio and LDL-cholesterol/HDL-cholesterol ratio were found to be statistically higher in the Indians than in the Malays and the Chinese. The differences between the Indians and the Chinese were statistically more significant than the differences between the Indians and the Malays. Our findings may partially explain the higher predisposition of the Indian community in Malaysia to CHD mortality and are consistent with those of other studies performed on Indian communities living outside the Indian subcontinent.

Observations of cloud cluster hierarchies over the tropical western Pacific

NASA Technical Reports Server (NTRS)

Lau, K. M.; Nakazawa, T.; Sui, C. H.

1991-01-01

The structure and propagation of tropical-cloud clusters are investigated during two contrasting periods over the tropical western Pacific in order to determine possible similarities or differences and to compare with previous studies. Three fundamental periodicities are found in tropical convection in the region: 1 day, 2-3 days, and 10-15 days. It is noted that the 10-15-day time scale is closely related to the intraseasonal oscillations propagating from the Indian Ocean to the western Pacific. Large convective complexes, supercloud clusters (SSC) are found to organize in this time scale. The SCC is made up from several cloud clusters generated at 2-3-day intervals. The diurnal variation is found to be most pronounced over the maritime continent, and the amplitude of the diurnal cycle is shown to be modulated by the 2-3-day and 10-15-day oscillations.

Persistence of lower birth weight in second generation South Asian babies born in the United Kingdom

PubMed Central

Margetts, B; Mohd, Y; Al, D; Jackson, A

2002-01-01

Objective: To assess differences in birth weight between all first and second generation South Asian babies born in Southampton, and trends since 1957. Design: Retrospective, cohort study. Setting: Birth records for babies born in Southampton from 1957 to 1996 were searched to identify all babies born of South Asian origin (including from the Indian subcontinent, East Africa, and elsewhere). Main outcome measures: All information recorded in the birth record about the mother and baby was extracted. Results: 2395 full term (>37 weeks; mean birth weight 3110; 95%CI 3092 to 3129) singleton births were identified. Detailed analysis was restricted to mothers either born in the Indian subcontinent (India, Pakistan, or Bangladesh (1435)) or United Kingdom (283). Mean birth weight and % low birth weight (<2500 g) were 3133 g (95%CI 3108 to 3157) and 7.5%, for first generation babies and 3046 g (2992 to 3099) and 11.7% for second generation babies. There was no trend over time to increased average birth weight in either first or second generation babies. Adjusting for other factors that were statistically significantly related to birth weight (gender, gestational age, mother's age, maternal weight at 15 weeks, parity, and mother's ethnic group) did not alter the trends. Conclusions: For that group in the UK who derive from the Indian subcontinent, average birth weight is significantly less than the national average. There has not been any increase in the average birth weight over the past 40 years, and the birth weight of babies of women who were born in the UK are no greater. The persistence of lower than desirable birth weight may result long term in higher than average rates of diabetes and heart disease in these groups. PMID:12177085

New evidence for paleobiogeographic intercontinental Gondwana relationships based on Late Cretaceous-earliest Paleocene coastal faunas from peninsular India

NASA Astrophysics Data System (ADS)

Sahni, Ashok; Rana, R. S.; Prasad, G. V. R.

A number of localities for freshwater microvertebrate assemblages of Late Cretaceous-early Paleocene age fringing the Deccan Basalt outcrops of Peninsular India have been studied during the last 4 years. The diversified vertebrate assemblages recovered by bulk wet screening at the localities of Rahioli (Gujarat), Jabalpur (Madhya Pradesh), Nagpur, Umrer, Pisdura (Maharashtra), and Asifabad (Andhra Pradesh) clearly suggest lack of faunal endemism for the drifting Indian island subcontinent. On the contrary, at the generic level, the fauna from the peninsular Indian localities is cosmopolitan in nature. The presence of a number of Laurasiatic elements, such as pelobatid frogs, suggests that a dispersal corridor was maintained with Laurasia throughout the drifting phase of India. The coastal plain faunas contain a mixed assemblage of freshwater and marine forms represented by 62 genera and 79 species. There is a striking similarity at the generic level between the fish and turtle faunas of the Upper Cretaceous of Peninsular India and those of Niger. Similarly, the few data now available from south central Bolivia, South America, also suggest interesting similarities to the corresponding faunas of Peninsular India. The lack of faunal endemism in India during the temporal span of India's northward drift as an island subcontinent can be attributed to a land contact maintained with Madagascar and the east African region by such aseismic elements as the Mascarene plateau and the Chagos-Laccadive Ridge. A more northerly contact with Laurasia may have been established by an island arc system represented at present by the Dras volcanics of Kashmir. The proximity of the Iran-Afghan plate to the drifting Indian landmass may have further contributed as a corridor for the dispersal of Laurasiatic elements into the subcontinent. By the middle Eocene, with the establishment of a firm dispersal corridor with central and east Asia, faunal affinities changed from Gondwanic to

Hepatitis E in Israel: A nation-wide retrospective study

PubMed Central

Erez-Granat, Ortal; Lachish, Tamar; Daudi, Nili; Shouval, Daniel; Schwartz, Eli

2016-01-01

AIM: To investigate the epidemiology, risk factors and clinical course of acute hepatitis E virus (HEV) infection in Israel, an industrialized country. METHODS: A retrospective analysis of acute HEV cases diagnosed in Israel from 1993 to 2013. Acute HEV was defined by ALT/AST elevation and a positive HEV PCR test or positive anti-HEV-IgM serology. HEV RNA was tested by quantitative reverse transcription PCR. Antibodies to HEV were tested retrospectively using an ELISA assay. HEV-RNA was sequenced using RT-PCR of ORF1 and ORF2 regions to diagnose genotype of the virus. Epidemiologic and clinical data were collected by reviewing the clinical files and through a telephone interview according to a structured questionnaire. RESULTS: Acute HEV was diagnosed in 68 patients. Among the 59 patients who gave an informed consent and were interviewed, 41% of infections were autochthonous (acquired in Israel), 44% travel-related and 15% imported by foreign workers. Autochthonous patients were mainly females (62.5%), more than half of them pregnant, 26% recalled consuming food or water in areas with poor sanitation, 44% ate non-kosher meat. Fulminant hepatitis developed in 3 patients (5%), all of them were females, two of them with post-partum infection, all acquired the disease in Israel (autochthonous). Israeli travelers with imported infection were predominantly males (73%), acquired the disease in the Indian subcontinent (81%), with 100% reporting having consumed fresh vegetables and drinks with ice cubes abroad. Six patients’ sera were tested for genotype and revealed HEV genotype 1 (all cases acquired in the Indian subcontinent). CONCLUSION: This is the first report which highlights the existence of hepatitis E as an autochthonous infection in Israel. Imported HEV originates mostly from the Indian subcontinent. PMID:27350735

Hepatitis E in Israel: A nation-wide retrospective study.

PubMed

Erez-Granat, Ortal; Lachish, Tamar; Daudi, Nili; Shouval, Daniel; Schwartz, Eli

2016-06-28

To investigate the epidemiology, risk factors and clinical course of acute hepatitis E virus (HEV) infection in Israel, an industrialized country. A retrospective analysis of acute HEV cases diagnosed in Israel from 1993 to 2013. Acute HEV was defined by ALT/AST elevation and a positive HEV PCR test or positive anti-HEV-IgM serology. HEV RNA was tested by quantitative reverse transcription PCR. Antibodies to HEV were tested retrospectively using an ELISA assay. HEV-RNA was sequenced using RT-PCR of ORF1 and ORF2 regions to diagnose genotype of the virus. Epidemiologic and clinical data were collected by reviewing the clinical files and through a telephone interview according to a structured questionnaire. Acute HEV was diagnosed in 68 patients. Among the 59 patients who gave an informed consent and were interviewed, 41% of infections were autochthonous (acquired in Israel), 44% travel-related and 15% imported by foreign workers. Autochthonous patients were mainly females (62.5%), more than half of them pregnant, 26% recalled consuming food or water in areas with poor sanitation, 44% ate non-kosher meat. Fulminant hepatitis developed in 3 patients (5%), all of them were females, two of them with post-partum infection, all acquired the disease in Israel (autochthonous). Israeli travelers with imported infection were predominantly males (73%), acquired the disease in the Indian subcontinent (81%), with 100% reporting having consumed fresh vegetables and drinks with ice cubes abroad. Six patients' sera were tested for genotype and revealed HEV genotype 1 (all cases acquired in the Indian subcontinent). This is the first report which highlights the existence of hepatitis E as an autochthonous infection in Israel. Imported HEV originates mostly from the Indian subcontinent.

Tamil in Melbourne

ERIC Educational Resources Information Center

Fernandez, Sue; Clyne, Michael

2007-01-01

There have been few Australian studies of language maintenance amongst immigrant languages from the Indian subcontinent. The present study focuses on Tamil speakers in Melbourne from Sri Lanka or India, who are Hindus or Christians. Tamil is a pluricentric language that has been under the domination of English in these countries, at least amongst…

Foot-and-Mouth Disease in the Middle East Caused by an A/ASIA/G-VII Virus Lineage, 2015-2016.

PubMed

Bachanek-Bankowska, Katarzyna; Di Nardo, Antonello; Wadsworth, Jemma; Henry, Elisabeth K M; Parlak, Ünal; Timina, Anna; Mischenko, Alexey; Qasim, Ibrahim Ahmad; Abdollahi, Darab; Sultana, Munawar; Hossain, M Anwar; King, Donald P; Knowles, Nick J

2018-06-01

Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015-2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent. Changes in a critical antigenic site within capsid viral protein 1 suggest possible evolutionary pressure caused by an intensive vaccination program.

Impact of atmospheric circulation types on southwest Asian dust and Indian summer monsoon rainfall

NASA Astrophysics Data System (ADS)

Kaskaoutis, D. G.; Houssos, E. E.; Solmon, F.; Legrand, M.; Rashki, A.; Dumka, U. C.; Francois, P.; Gautam, R.; Singh, R. P.

2018-03-01

This study examines the meteorological feedback on dust aerosols and rainfall over the Arabian Sea and India during the summer monsoon using satellite data, re-analysis and a regional climate model. Based on days with excess aerosol loading over the central Ganges basin during May - September, two distinct atmospheric circulation types (weather clusters) are identified, which are associated with different dust-aerosol and rainfall distributions over south Asia, highlighting the role of meteorology on dust emissions and monsoon rainfall. Each cluster is characterized by different patterns of mean sea level pressure (MSLP), geopotential height at 700 hPa (Z700) and wind fields at 1000 hPa and at 700 hPa, thus modulating changes in dust-aerosol loading over the Arabian Sea. One cluster is associated with deepening of the Indian/Pakistan thermal low leading to (i) increased cyclonicity and thermal convection over northwestern India and Arabian Peninsula, (ii) intensification of the southwest monsoon off the Horn of Africa, iii) increase in dust emissions from Rub-Al-Khali and Somalian deserts, (iv) excess dust accumulation over the Arabian Sea and, (v) strengthening of the convergence of humid air masses and larger precipitation over Indian landmass compared to the other cluster. The RegCM4.4 model simulations for dust-aerosol and precipitation distributions support the meteorological fields and satellite observations, while the precipitation over India is positively correlated with the aerosol loading over the Arabian Sea on daily basis for both weather clusters. This study highlights the key role of meteorology and atmospheric dynamics on dust life cycle and rainfall over the monsoon-influenced south Asia.

Modified osteo-odonto keratoprosthesis--the Indian experience--results of the first 50 cases.

PubMed

Iyer, Geetha; Pillai, Vinay S; Srinivasan, Bhaskar; Falcinelli, Giovanni; Padmanabhan, Prema; Guruswami, Sitalakshmi; Falcinelli, Giancarlo

2010-07-01

To study the results of the modified osteo-odonto keratoprosthesis (MOOKP) surgery in bilateral end-stage ocular surface disorders. The MOOKP surgery is performed as a routine in 3 stages. Stage 1A involves removal of the iris and anterior vitrectomy with a corneal transplant if indicated. Stage 1B + 1C usually performed simultaneously involves harvesting the buccal mucosa and transplanting it onto the ocular surface along with fashioning of the osteo-odonto alveolar lamina. Stage 2 involves transplanting the osteo-odonto alveolar lamina to the eye 3 months later. The MOOKP surgery was completed in 50 eyes of 47 patients with a mean follow-up of 15.38 months (range: 1-54 months). Anatomic success was achieved in 96% of the eyes. Functional success of visual acuity > or = 20/60 was noted in 66% of eyes. Complications included oroantral fistula (6%), trophic mucosal alterations (8%), lamina exposure (central 6% and peripheral 8%), mucous membrane overgrowth (2%), hypotony (2%), expulsion of optic cylinder (4%), endophthalmitis (2%), glaucoma (20%), sterile vitritis (6%), and retinal detachment (2%). MOOKP is the keratoprosthesis of choice in bilateral end-stage ocular surface disorders in the Indian subcontinent. Complications do occur and have to be recognized and treated early.

National survey of tuberculosis notifications in England and Wales 1978--9. Report from the Medical Research Council Tuberculosis and Chest Diseases Unit.

PubMed Central

1980-01-01

A survey of all tuberculosis notifications in England and Wales for a six-month period showed that 70% of 3732 newly notified, previously untreated patients had respiratory disease only, 23% had non-respiratory disease only, and 7% had both. Fifty-seven per cent of patients were of white and 35% were of Indian subcontinent (Indian, Pakistani, or Bangladeshi) ethnic origin, the latter group contributing over half the cases of non-respiratory disease. The estimated overall annual notification rate per 100 000 population for 1978--9 was 16.4 for England and 13.5 for Wales. The rates differed considerably between the different ethnic groups in England, the highest rates occurring in the Indian and in the Pakistani and Bangladeshi groups and the lowest in the white group; the differences in the non-respiratory rates were the more striking. Nearly a quarter of patients with respiratory disease had large pulmonary lesions, the proportion being higher for the white group than for the Indian subcontinent group. Over half the patients had positive cultures for tubercle bacilli and over a third had positive smears; both proportions were higher for the white group. This survey has identified many of the problems which tuberculosis presents in England and Wales today. These include the substantial number of patients with sputum-positive disease, the considerable variation in the rates in the different ethnic groups, and the not uncommon occurrence of childhood tuberculosis. PMID:7427500

Holocene aridification of India

USGS Publications Warehouse

Ponton, C.; Giosan, L.; Eglinton, T.I.; Fuller, D.Q.; Johnson, J.E.; Kumar, P.; Collett, T.S.

2012-01-01

Spanning a latitudinal range typical for deserts, the Indian peninsula is fertile instead and sustains over a billion people through monsoonal rains. Despite the strong link between climate and society, our knowledge of the long-term monsoon variability is incomplete over the Indian subcontinent. Here we reconstruct the Holocene paleoclimate in the core monsoon zone (CMZ) of the Indian peninsula using a sediment core recovered offshore from the mouth of Godavari River. Carbon isotopes of sedimentary leaf waxes provide an integrated and regionally extensive record of the flora in the CMZ and document a gradual increase in aridity-adapted vegetation from ???4,000 until 1,700 years ago followed by the persistence of aridity-adapted plants after that. The oxygen isotopic composition of planktonic foraminifer Globigerinoides ruber detects unprecedented high salinity events in the Bay of Bengal over the last 3,000 years, and especially after 1,700 years ago, which suggest that the CMZ aridification intensified in the late Holocene through a series of sub-millennial dry episodes. Cultural changes occurred across the Indian subcontinent as the climate became more arid after ???4,000 years. Sedentary agriculture took hold in the drying central and south India, while the urban Harappan civilization collapsed in the already arid Indus basin. The establishment of a more variable hydroclimate over the last ca. 1,700 years may have led to the rapid proliferation of water-conservation technology in south India. Copyright 2012 by the American Geophysical Union.

Numerical weather prediction in low latitudes

NASA Technical Reports Server (NTRS)

Krishnamurti, T. N.

1985-01-01

Based on the results of a number of numerical prediction experiments, the differential heating between land and ocean is an important and critical factor for investigation of phenomenon such as the onset of monsoons over the Indian subcontinent. The pre-onset period during the month of May shows a rather persistent flow field in the monsoon region. At low levels the circulation exhibits anticyclonic excursions over the Arabian Sea, flowing essentially parallel to the west coast of India from the north. Over the Indian subcontinent the major feature is a shallow heat low over northern India. As the heat sources commence a rapid northwestward movement toward the southern edge of the Tibetan Plateau, an interesting configuration of the large-scale divergent circulation occurs. A favorable configuration for a rapid exchange of energy from the divergent to the rotational kinetic energy develops. Strong low level monsoonal circulations evolve, attendant with that the onset of monsoon rains occurs. In order to test this observational sequence, a series of short-range numerical prediction experiments were initiated to define the initial heat sources.

Metagenomic Exploration of Viruses throughout the Indian Ocean

PubMed Central

Lorenzi, Hernan A.; Fadrosh, Douglas W.; Brami, Daniel; Thiagarajan, Mathangi; McCrow, John P.; Tovchigrechko, Andrey; Yooseph, Shibu; Venter, J. Craig

2012-01-01

The characterization of global marine microbial taxonomic and functional diversity is a primary goal of the Global Ocean Sampling Expedition. As part of this study, 19 water samples were collected aboard the Sorcerer II sailing vessel from the southern Indian Ocean in an effort to more thoroughly understand the lifestyle strategies of the microbial inhabitants of this ultra-oligotrophic region. No investigations of whole virioplankton assemblages have been conducted on waters collected from the Indian Ocean or across multiple size fractions thus far. Therefore, the goals of this study were to examine the effect of size fractionation on viral consortia structure and function and understand the diversity and functional potential of the Indian Ocean virome. Five samples were selected for comprehensive metagenomic exploration; and sequencing was performed on the microbes captured on 3.0-, 0.8- and 0.1 µm membrane filters as well as the viral fraction (<0.1 µm). Phylogenetic approaches were also used to identify predicted proteins of viral origin in the larger fractions of data from all Indian Ocean samples, which were included in subsequent metagenomic analyses. Taxonomic profiling of viral sequences suggested that size fractionation of marine microbial communities enriches for specific groups of viruses within the different size classes and functional characterization further substantiated this observation. Functional analyses also revealed a relative enrichment for metabolic proteins of viral origin that potentially reflect the physiological condition of host cells in the Indian Ocean including those involved in nitrogen metabolism and oxidative phosphorylation. A novel classification method, MGTAXA, was used to assess virus-host relationships in the Indian Ocean by predicting the taxonomy of putative host genera, with Prochlorococcus, Acanthochlois and members of the SAR86 cluster comprising the most abundant predictions. This is the first study to holistically

Susceptibility to SLE in South Indian Tamils may be influenced by genetic selection pressure on TLR2 and TLR9 genes.

PubMed

Devaraju, Panneer; Gulati, Reena; Antony, Paul T; Mithun, C B; Negi, Vir S

2015-03-01

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder with complex etiology. Genetics plays an important role in lupus pathogenesis through its influence on clinical and autoantibody phenotype of the disease. Toll like receptors (TLR) recognize molecular patterns of pathogens and activate the innate immune system. Their ability to identify nucleic acids makes them suitable candidates for investigation of their role in lupus pathogenesis. Hence, this study was carried out to analyze the G to A and C to T transitions in TLR2 and TLR9 genes respectively and to test their association with lupus susceptibility, clinical and autoantibody phenotypes in South Indian Tamils. Three hundred SLE patients fulfilling ACR 2012 criteria for SLE and 460 age, sex similar, ethnicity matched controls were recruited as cases and controls. TLR2 (R753Q) and TLR9 (-1237C/T) polymorphisms were analyzed by real time PCR. The TLR2 gene remained monomorphic in patients and controls, the frequency of the homozygous wild type allele being 100% and 99.6% respectively. Hence, it did not confer susceptibility to SLE. The more frequent T allele of TLR9 gene conferred a significant risk to develop SLE (p=0.011, OR 1.69, 95% CI 1.1-2.6). Both the polymorphisms did not influence clinical or autoantibody phenotype of the disease. Prevailing endemic infections in the Indian subcontinent may have exerted a selection pressure resulting in TLR2 gene remaining monomorphic and the TLR9 adapting to a mutation for its increased expression. These may have an additive effect in the presence of other genetic and environmental risk factors to confer susceptibility to SLE in South Indian Tamils. Copyright © 2014 Elsevier Ltd. All rights reserved.

Taking Care of Our Own: Training Indians to Heal Indians.

ERIC Educational Resources Information Center

Ambler, Marjane

1994-01-01

Describes the role of tribally controlled colleges in increasing the number of American Indian physicians working as a part of the Indian Health Service. Discusses health problems in the Indian community. Reviews the benefits and difficulties of Indian doctors working in their own communities. (MAB)

Drinking habits in ancient India

PubMed Central

Somasundaram, Ottilingam; Raghavan, D. Vijaya; Murthy, A. G. Tejus

2016-01-01

Consumption of one or other form of intoxicating substances has been present throughout the history of the world. This article traces such use in the Indian subcontinent, both in North and South India. References to the use of intoxicants are to be found in the Vedas, the Great Epics, and the ancient Tamil literature. PMID:26985113

Teacher Transculturalism and Cultural Difference: Addressing Racism in Australian Schools

ERIC Educational Resources Information Center

Casinader, Niranjan R.; Walsh, Lucas

2015-01-01

The increasing cultural diversity of students in Australia's schools is one of the salient changes in education over the last 30 years. In 2011, nearly half of all Australians had one or more parents born overseas, with migration from China, the Indian subcontinent and Africa increasing during the early 2000s (Australian Bureau of Statistics,…

2 CFR 200.54 - Indian tribe (or “federally recognized Indian tribe”).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Indian tribe (or âfederally recognized Indian tribeâ). 200.54 Section 200.54 Grants and Agreements Office of Management and Budget Guidance for... § 200.54 Indian tribe (or “federally recognized Indian tribe”). Indian tribe means any Indian tribe...

Seasonal variations of thermocline circulation and ventilation in the Indian Ocean

NASA Astrophysics Data System (ADS)

You, Yuzhu

1997-05-01

Two seasonal hydrographic data sets, including temperature, salinity, dissolved oxygen, and nutrients, are used in a mixing model which combines cluster analysis with optimum multiparameter analysis to determine the spreading and mixing of the thermocline waters in the Indian Ocean. The mixing model comprises a system of four major source water masses, which were identified in the thermocline through cluster analysis. They are Indian Central Water (ICW), North Indian Central Water (NICW) interpreted as aged ICW, Australasian Mediterranean Water (AAMW), and Red Sea Water (RSW)/Persian Gulf Water (PGW). The mixing ratios of these water masses are quantified and mapped on four isopycnal surfaces which span the thermocline from 150 to 600 m in the northern Indian Ocean, on two meridional sections along 60°E and 90°E, and on two zonal sections along 10°S and 6°N. The mixing ratios and pathways of the thermocline water masses show large seasonal variations, particularly in the upper 400-500 m of the thermocline. The most prominent signal of seasonal variation occurs in the Somali Current, the western boundary current, which appears only during the SW (summer) monsoon. The northward spreading of ICW into the equatorial and northern Indian Ocean is by way of the Somali Current centered at 300-400 m on the σθ=26.7 isopycnal surface during the summer monsoon and of the Equatorial Countercurrent during the NE (winter) monsoon. More ICW carried into the northern Indian Ocean during the summer monsoon is seen clearly in the zonal section along 6°N. NICW spreads southward through the western Indian Ocean and is stronger during the winter monsoon. AAMW appears in both seasons but is slightly stronger during the summer in the upper thermocline. The westward flow of AAMW is by way of the South Equatorial Current and slightly bends to the north on the σθ=26.7 isopycnal surface during the summer monsoon, indicative of its contribution to the western boundary current. Outflow

Surface Nutrient Utilisation and Productivity During Glacial-Interglacial Periods from the Equatorial Indian Ocean

NASA Astrophysics Data System (ADS)

R, C. K.; Bhushan, R.; Agnihotri, R.; Sawlani, R.; Jull, A. J. T.

2016-12-01

Seawaters and underlying sediments off Sri Lanka provide a unique marine realm affected by both branches of Northern Indian Ocean i.e. Arabian Sea (AS) and Bay of Bengal (BOB). AS and BOB are known for their distinct response to southwest monsoon. AS experiencing mainly winds and upwelling while BOB receives precipitation driven surface runoff from the Indian sub-continent. Multiple proxies were measured on a radiocarbon dated sediment core raised off Sri Lanka; their down core variations were used to understand oceanic history (nutrient utilisation, surface productivity, nature of organic matter) spanning last glacial-interglacial cycle ( 26 to 2.5 ka BP). Variations in CaCO3, biogenic silica (BSi) and δ15N from 26 ka to 12.5 ka BP indicate the region was experiencing high surface productivity with probably reduced surface nutrient utilisation efficiency. Sedimentary δ15N depth profile is decoupled from down core variations of major productivity indices (e.g. CaCO3, OC), hinting plausibly partial utilization of nutrients in the mixed layer (photic zone). δ13C of OC and C/N (wt. ratio) clearly reveal the terrestrial origin of organic matter at 15 ka BP, a period known for witnessing onset of deglaciation in northern hemisphere. δ13C minimum at 9 ka BP indicates intense monsoonal activity during this time coinciding well with solar insolation (June) maximum of the northern hemisphere. With the onset of Holocene ( 11 ka BP), δ15N variations appear to correlate with BSi and Ba/Ti indicating enhanced utilization of available nutrients at surface. Suggesting surface productivity over the region was probably micro-nutrient limited. The increased inventory of terrestrial runoff in Holocene probably demonstrates enhanced carbon sequestration capability of the region.

Domestic Animals and Epidemiology of Visceral Leishmaniasis, Nepal

PubMed Central

Bhattarai, Narayan Raj; Van der Auwera, Gert; Rijal, Suman; Picado, Albert; Speybroeck, Niko; Khanal, Basudha; De Doncker, Simonne; Das, Murari Lal; Ostyn, Bart; Davies, Clive; Coosemans, Marc; Berkvens, Dirk; Boelaert, Marleen

2010-01-01

On the Indian subcontinent, visceral leishmaniasis (VL) is considered an anthroponosis. To determine possible reasons for its persistence during interepidemic periods, we mapped Leishmania infections among healthy persons and animals in an area of active VL transmission in Nepal. During 4 months (September 2007–February 2008), blood was collected from persons, goats, cows, and buffaloes in 1 village. Leishmania infections were determined by using PCR. We found infections among persons (6.1%), cows (5%), buffaloes (4%), and goats (16%). Data were georeferenced and entered into a geographic information system. The bivariate K-function results indicated spatial clustering of Leishmania spp.–positive persons and domestic animals. Classification tree analysis determined that among several possible risk factors for Leishmania infection among persons, proximity of Leishmania spp.–positive goats ranked first. Although our data do not necessarily mean that goats constitute a reservoir host of L. donovani, these observations indicate the need for further investigation of goats’ possible role in VL transmission. PMID:20113552

Measuring reproductive tourism through an analysis of Indian ART clinic Websites.

PubMed

Deonandan, Raywat; Loncar, Mirhad; Rahman, Prinon; Omar, Sabrina

2012-01-01

India is fast becoming the most prominent player in the global industry of reproductive tourism, in which infertile people cross international borders to seek assisted reproduction technologies. This study was conducted to better understand the extent and manner in which Indian clinics seek foreign clients. A systematic search of official Indian assisted reproduction technologies clinic Websites was undertaken, and instances noted where foreign clients were overtly targeted, and where maternal surrogacy was overtly offered. A total of 159 clinics with Web addresses were identified, though only 78 had functioning Websites. All were published in English, with the majority clustered in the states of Maharashtra (14) and Gujarat (9). Of the 78 functioning Websites, 53 (68%) featured some mention of maternal surrogacy services, and 42 (54%) made overt overtures to foreign clients. Qualitative appeals to foreigners included instructions for international adoption, visa application, and the legal parental disposition of the surrogate. All Maharashtran clinic Websites that mentioned surrogacy also overtly featured reproductive tourism. Preimplantation diagnosis services were not offered disproportionately by clinics mentioning reproductive tourism. Based upon clinic online profiles, reproductive tourism comprises a substantial fraction of India's assisted reproduction technologies clinics' business focus, clustering around its most tourist-friendly locales, and surrogacy may be a strong motivator for international clientele.

Red Women, White Policy: American Indian Women and Indian Education.

ERIC Educational Resources Information Center

Warner, Linda Sue

This paper discusses American Indian educational policies and implications for educational leadership by Indian women. The paper begins with an overview of federal Indian educational policies from 1802 to the 1970s. As the tribes have moved toward self-determination in recent years, a growing number of American Indian women have assumed leadership…

Emerging role of Indian ocean on Indian northeast monsoon

NASA Astrophysics Data System (ADS)

Yadav, Ramesh Kumar

2013-07-01

This study examines the emerging role of Indian Ocean sea surface temperature (SST) on the inter-annual variability (IAV) of Indian north-east monsoon rainfall (NEMR). The IAV of NEMR is associated with the warm SST anomaly over east Bay-of-Bengal (BoB) (88.5oE-98.5oE; 8.5oN-15.5oN) and cool SST anomaly over east equatorial Indian Ocean (80.5oE-103.5oE; 6.5oS-3.5oN). The gradient of SST between these boxes (i.e. northern box minus southern box) shows strong and robust association with the Indian NEMR variability in the recent decades. For establishing the teleconnections, SST, mean sea level pressure, North Indian Ocean tropical storm track, and circulation data have been used. The study reveals that during the positive SST gradient years, the inter-tropical convergence zone (ITCZ) shifts northwards over the East Indian Ocean. The tropical depressions, storms and cyclones formed in the North Indian Ocean moves more zonally and strike the southern peninsular India and hence excess NEMR. While, during the negative SST gradient years, the ITCZ shifts southwards over the Indian Ocean. The tropical depressions, storms and cyclones formed in the North Indian Ocean moves more northwestward direction and after crossing 15oN latitude re-curve to north-east direction towards head BoB and misses southern peninsular India and hence, deficient NEMR.

Analysis of Tropical Cyclone Tracks in the North Indian Ocean

NASA Astrophysics Data System (ADS)

Patwardhan, A.; Paliwal, M.; Mohapatra, M.

2011-12-01

Cyclones are regarded as one of the most dangerous meteorological phenomena of the tropical region. The probability of landfall of a tropical cyclone depends on its movement (trajectory). Analysis of trajectories of tropical cyclones could be useful for identifying potentially predictable characteristics. There is long history of analysis of tropical cyclones tracks. A common approach is using different clustering techniques to group the cyclone tracks on the basis of certain characteristics. Various clustering method have been used to study the tropical cyclones in different ocean basins like western North Pacific ocean (Elsner and Liu, 2003; Camargo et al., 2007), North Atlantic Ocean (Elsner, 2003; Gaffney et al. 2007; Nakamura et al., 2009). In this study, tropical cyclone tracks in the North Indian Ocean basin, for the period 1961-2010 have been analyzed and grouped into clusters based on their spatial characteristics. A tropical cyclone trajectory is approximated as an open curve and described by its first two moments. The resulting clusters have different centroid locations and also differently shaped variance ellipses. These track characteristics are then used in the standard clustering algorithms which allow the whole track shape, length, and location to be incorporated into the clustering methodology. The resulting clusters have different genesis locations and trajectory shapes. We have also examined characteristics such as life span, maximum sustained wind speed, landfall, seasonality, many of which are significantly different across the identified clusters. The clustering approach groups cyclones with higher maximum wind speed and longest life span in to one cluster. Another cluster includes short duration cyclonic events that are mostly deep depressions and significant for rainfall over Eastern and Central India. The clustering approach is likely to prove useful for analysis of events of significance with regard to impacts.

Spatial and temporal distribution of the seismicity along two mid-oceanic ridges with contrasted spreading rates in the Indian Ocean

NASA Astrophysics Data System (ADS)

Tsang-Hin-Sun, E.; Perrot, J.; Royer, J. Y.

2015-12-01

The seismicity of the ultra-slow spreading Southwest (14 mm/y) and intermediate spreading Southeast (60 mm/y) Indian ridges was monitored from February 2012 to March 2013 by the OHASISBIO array of 7 autonomous hydrophones. A total of 1471 events were located with 4 instruments or more, inside the array, with a median location uncertainty < 5 km and a completeness magnitude of mb = 3. Both ridges display similar average rates of seismicity, suggesting that there is no systematic relationship between seismicity and spreading rates. Accretion modes do differ, however, by the along-axis distribution of the seismic events. Along the ultra-slow Southwest Indian Ridge, events are sparse but regularly spaced and scattered up to 50 km off-axis. Along the fast Southeast Indian Ridge, events are irregularly distributed, focusing in narrow regions near the ridge axis at segment ends and along transform faults, whereas ridge-segment centers generally appear as seismic gaps (at the level of completeness of the array). Only two clusters, 6 months apart, are identified in a segment-center at 29°S. From the temporal distribution of the clustered events and comparisons with observations in similar mid-oceanic ridge setting, both clusters seem to have a volcanic origin and to be related to a dike emplacement or a possible eruption on the seafloor. Their onset time and migration rate are comparable to volcanic swarms recorded along the Juan de Fuca Ridge. Overall, the rate of seismicity along the two Indian spreading ridges correlates with the large-scale variations in the bathymetry and shear-wave velocity anomaly in the upper mantle, suggesting that the distribution of the low-magnitude seismicity is mainly controlled by along-axis variations in the lithosphere rheology and temperature.

2 CFR 25.335 - Indian Tribe (or “Federally recognized Indian Tribe”).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Indian Tribe (or âFederally recognized Indian Tribeâ). 25.335 Section 25.335 Grants and Agreements Office of Management and Budget Guidance for....335 Indian Tribe (or “Federally recognized Indian Tribe”). Indian Tribe (or “Federally recognized...

2 CFR 25.335 - Indian Tribe (or “Federally recognized Indian Tribe”).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Indian Tribe (or âFederally recognized Indian Tribeâ). 25.335 Section 25.335 Grants and Agreements Office of Management and Budget Guidance for....335 Indian Tribe (or “Federally recognized Indian Tribe”). Indian Tribe (or “Federally recognized...

2 CFR 25.335 - Indian Tribe (or “Federally recognized Indian Tribe”).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Indian Tribe (or âFederally recognized Indian Tribeâ). 25.335 Section 25.335 Grants and Agreements Office of Management and Budget Guidance for....335 Indian Tribe (or “Federally recognized Indian Tribe”). Indian Tribe (or “Federally recognized...

Lean Manufacturing Auto Cluster at Chennai

NASA Astrophysics Data System (ADS)

Bhaskaran, E.

2012-10-01

Due the presence of lot of automotive Industry, Chennai is known as Detroit of India, that producing over 40 % of the Indian vehicle and components. Lean manufacturing concepts have been widely recognized as an important tool in improving the competitiveness of industries. This is a continuous process involving everyone, starting from management to the shop floor. Automotive Component Industries (ACIs) in Ambattur Industrial Estate, Chennai has formed special purpose vehicle (SPV) society namely Ambattur Industrial Estate Manufacturers Association (AIEMA) Technology Centre (ATC) lean manufacturing cluster (ATC-LMC) during July 2010 under lean manufacturing competitiveness scheme, that comes under National Manufacturing Competitiveness Programme of Government of India. The Tripartite Agreement is taken place between National Productivity Council, consultants and cluster (ATC-LMC). The objective is to conduct diagnostic study, study on training and application of various lean manufacturing techniques and auditing in ten ACIs. The methodology adopted is collection of primary data/details from ten ACIs. In the first phase, diagnostic study is done and the areas for improvement in each of the cluster member companies are identified. In the second phase, training programs and implementation is done on 5S and other areas. In the third phase auditing is done and found that the lean manufacturing techniques implementation in ATC-LMC is sustainable and successful in every cluster companies, which will not only enhance competitiveness but also decrease cost, time and increase productivity. The technical efficiency of LMC companies also increases significantly.

Unravelling the distinct strains of Tharu ancestry

PubMed Central

Chaubey, Gyaneshwer; Singh, Manvendra; Crivellaro, Federica; Tamang, Rakesh; Nandan, Amrita; Singh, Kamayani; Sharma, Varun Kumar; Pathak, Ajai Kumar; Shah, Anish M; Sharma, Vishwas; Singh, Vipin Kumar; Selvi Rani, Deepa; Rai, Niraj; Kushniarevich, Alena; Ilumäe, Anne-Mai; Karmin, Monika; Phillip, Anand; Verma, Abhilasha; Prank, Erik; Singh, Vijay Kumar; Li, Blaise; Govindaraj, Periyasamy; Chaubey, Akhilesh Kumar; Dubey, Pavan Kumar; Reddy, Alla G; Premkumar, Kumpati; Vishnupriya, Satti; Pande, Veena; Parik, Jüri; Rootsi, Siiri; Endicott, Phillip; Metspalu, Mait; Lahr, Marta Mirazon; van Driem, George; Villems, Richard; Kivisild, Toomas; Singh, Lalji; Thangaraj, Kumarasamy

2014-01-01

The northern region of the Indian subcontinent is a vast landscape interlaced by diverse ecologies, for example, the Gangetic Plain and the Himalayas. A great number of ethnic groups are found there, displaying a multitude of languages and cultures. The Tharu is one of the largest and most linguistically diverse of such groups, scattered across the Tarai region of Nepal and bordering Indian states. Their origins are uncertain. Hypotheses have been advanced postulating shared ancestry with Austroasiatic, or Tibeto-Burman-speaking populations as well as aboriginal roots in the Tarai. Several Tharu groups speak a variety of Indo-Aryan languages, but have traditionally been described by ethnographers as representing East Asian phenotype. Their ancestry and intra-population diversity has previously been tested only for haploid (mitochondrial DNA and Y-chromosome) markers in a small portion of the population. This study presents the first systematic genetic survey of the Tharu from both Nepal and two Indian states of Uttarakhand and Uttar Pradesh, using genome-wide SNPs and haploid markers. We show that the Tharu have dual genetic ancestry as up to one-half of their gene pool is of East Asian origin. Within the South Asian proportion of the Tharu genetic ancestry, we see vestiges of their common origin in the north of the South Asian Subcontinent manifested by mitochondrial DNA haplogroup M43. PMID:24667789

Unravelling the distinct strains of Tharu ancestry.

PubMed

Chaubey, Gyaneshwer; Singh, Manvendra; Crivellaro, Federica; Tamang, Rakesh; Nandan, Amrita; Singh, Kamayani; Sharma, Varun Kumar; Pathak, Ajai Kumar; Shah, Anish M; Sharma, Vishwas; Singh, Vipin Kumar; Selvi Rani, Deepa; Rai, Niraj; Kushniarevich, Alena; Ilumäe, Anne-Mai; Karmin, Monika; Phillip, Anand; Verma, Abhilasha; Prank, Erik; Singh, Vijay Kumar; Li, Blaise; Govindaraj, Periyasamy; Chaubey, Akhilesh Kumar; Dubey, Pavan Kumar; Reddy, Alla G; Premkumar, Kumpati; Vishnupriya, Satti; Pande, Veena; Parik, Jüri; Rootsi, Siiri; Endicott, Phillip; Metspalu, Mait; Lahr, Marta Mirazon; van Driem, George; Villems, Richard; Kivisild, Toomas; Singh, Lalji; Thangaraj, Kumarasamy

2014-12-01

The northern region of the Indian subcontinent is a vast landscape interlaced by diverse ecologies, for example, the Gangetic Plain and the Himalayas. A great number of ethnic groups are found there, displaying a multitude of languages and cultures. The Tharu is one of the largest and most linguistically diverse of such groups, scattered across the Tarai region of Nepal and bordering Indian states. Their origins are uncertain. Hypotheses have been advanced postulating shared ancestry with Austroasiatic, or Tibeto-Burman-speaking populations as well as aboriginal roots in the Tarai. Several Tharu groups speak a variety of Indo-Aryan languages, but have traditionally been described by ethnographers as representing East Asian phenotype. Their ancestry and intra-population diversity has previously been tested only for haploid (mitochondrial DNA and Y-chromosome) markers in a small portion of the population. This study presents the first systematic genetic survey of the Tharu from both Nepal and two Indian states of Uttarakhand and Uttar Pradesh, using genome-wide SNPs and haploid markers. We show that the Tharu have dual genetic ancestry as up to one-half of their gene pool is of East Asian origin. Within the South Asian proportion of the Tharu genetic ancestry, we see vestiges of their common origin in the north of the South Asian Subcontinent manifested by mitochondrial DNA haplogroup M43.

Indian Ledger Art.

ERIC Educational Resources Information Center

Chilcoat, George W.

1990-01-01

Offers an innovative way to teach mid-nineteenth century North American Indian history by having students create their own Indian Ledger art. Purposes of the project are: to understand the role played by American Indians, to reveal American Indian stereotypes, and to identify relationships between cultures and environments. Background and…

Wisconsin Indians.

ERIC Educational Resources Information Center

Lurie, Nancy Oestreich

Wisconsin encompasses an astonishingly representative illustration of the total historical development of federal Indian policy and Indian reactions to it. Wisconsin's Indian population (at least 25,000 people) is the third largest east of the Mississippi River and offers great diversity (3 major linguistic stocks, 6 broad tribal affiliations, and…

Prevalence of common disease-associated variants in Asian Indians

PubMed Central

Pemberton, Trevor J; Mehta, Niyati U; Witonsky, David; Di Rienzo, Anna; Allayee, Hooman; Conti, David V; Patel, Pragna I

2008-01-01

Background Asian Indians display a high prevalence of diseases linked to changes in diet and environment that have arisen as their lifestyle has become more westernized. Using 1200 genome-wide polymorphisms in 432 individuals from 15 Indian language groups, we have recently shown that: (i) Indians constitute a distinct population-genetic cluster, and (ii) despite the geographic and linguistic diversity of the groups they exhibit a relatively low level of genetic heterogeneity. Results We investigated the prevalence of common polymorphisms that have been associated with diseases, such as atherosclerosis (ALOX5), hypertension (CYP3A5, AGT, GNB3), diabetes (CAPN10, TCF7L2, PTPN22), prostate cancer (DG8S737, rs1447295), Hirschsprung disease (RET), and age-related macular degeneration (CFH, LOC387715). In addition, we examined polymorphisms associated with skin pigmentation (SLC24A5) and with the ability to taste phenylthiocarbamide (TAS2R38). All polymorphisms were studied in a cohort of 576 India-born Asian Indians sampled in the United States. This sample consisted of individuals whose mother tongue is one of 14 of the 22 "official" languages recognized in India as well as individuals whose mother tongue is Parsi, a cultural group that has resided in India for over 1000 years. Analysis of the data revealed that allele frequency differences between the different Indian language groups were small, and interestingly the variant alleles of ALOX5 g.8322G>A and g.50778G>A, and PTPN22 g.36677C>T were present only in a subset of the Indian language groups. Furthermore, a latitudinal cline was identified both for the allele frequencies of the SNPs associated with hypertension (CYP3A5, AGT, GNB3), as well as for those associated with the ability to taste phenylthiocarbamide (TAS2R38). Conclusion Although caution is warranted due to the fact that this US-sampled Indian cohort may not represent a random sample from India, our results will hopefully assist in the design of future

Identification of dust storm source areas in West Asia using multiple environmental datasets.

PubMed

Cao, Hui; Amiraslani, Farshad; Liu, Jian; Zhou, Na

2015-01-01

Sand and Dust storms are common phenomena in arid and semi-arid areas. West Asia Region, especially Tigris-Euphrates alluvial plain, has been recognized as one of the most important dust source areas in the world. In this paper, a method is applied to extract SDS (Sand and Dust Storms) sources in West Asia region using thematic maps, climate and geography, HYSPLIT model and satellite images. Out of 50 dust storms happened during 2000-2013 and collected in form of MODIS images, 27 events were incorporated as demonstrations of the simulated trajectories by HYSPLIT model. Besides, a dataset of the newly released Landsat images was used as base-map for the interpretation of SDS source regions. As a result, six main clusters were recognized as dust source areas. Of which, 3 clusters situated in Tigris-Euphrates plain were identified as severe SDS sources (including 70% dust storms in this research). Another cluster in Sistan plain is also a potential source area. This approach also confirmed six main paths causing dust storms. These paths are driven by the climate system including Siberian and Polar anticyclones, monsoon from Indian Subcontinent and depression from north of Africa. The identification of SDS source areas and paths will improve our understandings on the mechanisms and impacts of dust storms on socio-economy and environment of the region. Copyright © 2014 Elsevier B.V. All rights reserved.

American Indians Today.

ERIC Educational Resources Information Center

Snipp, C. Matthew

This paper reviews American Indian demography and the political and economic conditions on Indian reservations. After collapsing during the 19th century, the American Indian population grew gradually during the early 20th century, approaching 2 million in 1990. American Indians are heavily concentrated in the West, northern Midwest, and Oklahoma;…

Indian Studies Program.

ERIC Educational Resources Information Center

Peck, Cy, Sr.; And Others

A product of the Indian Studies Curriculum Committee and the Indian Studies Staff, this manual on the Indians of Southeast Alaska constitutes a useable classroom tool designed for the cross-cultural program in the Juneau School District. Objectives of this Indian Studies Program are identified as: to increase knowledge, awareness, and positive…

Young Once, Indian Forever: Youth Gangs in Indian Country

ERIC Educational Resources Information Center

Bell, James; Lim, Nicole

2005-01-01

Not unlike mainstream society of the United States, Indian Country faces new challenges regarding the values, mores, and behavior of its young people. Since their first encounters with European explorers, American Indians have fought to preserve their culture and traditions. Federal policies that addressed the "Indian problem" by…

Implementation of Indian Control of Indian Education. Booklet No. 1. Revised.

ERIC Educational Resources Information Center

Kirkness, Verna J.

The ten questions and their respective answers comprising this booklet illustrate a growing movement toward Indian control of Indian education. This movement is a policy of the National Indian Brotherhood of Canada based on parental responsibility and local control which recognizes that Indian people through their elected councils have the right…

Achievements of ATS-6 beacon experiment over Indian sub-continent

NASA Technical Reports Server (NTRS)

Deshpande, M. R.; Rastogi, R. G.; Vats, H. O.; Sethia, G.; Chandra, H.; Davies, K.; Grubb, R. N.; Jones, J. E.

1978-01-01

The repositioning of the ATS-6 satellite at 34 deg E enabled the scientific community of India to use the satellite's radio beacon for ionospheric studies. Two scientific projects were undertaken. The objective of the first project was to map ionospheric electron content, range rate errors, traveling ionospheric phenomena, solar flare effect, and magnetic phenomena. The second project was aimed at studying geophysical phenomena associated with the equatorial electrojet. The principal results of these studies are described.

On the association between pre-monsoon aerosol and all-India summer monsoon rainfall

NASA Astrophysics Data System (ADS)

Patil, S. D.; Preethi, B.; Bansod, S. D.; Singh, H. N.; Revadekar, J. V.; Munot, A. A.

2013-09-01

Summer monsoon rainfall which gives 75-90% of the annual rainfall plays vital role in Indian economy as the food grain production in India is very much dependent on the summer monsoon rainfall. It has been suggested by recent studies that aerosol loading over the Indian region plays significant role in modulating the monsoon circulation and consequent rainfall distribution over the Indian sub-continent. Increased industrialization and the increasing deforestation over past few decades probably cause a gradual increase in the aerosol concentration. A significant negative relationship between pre-monsoon (March-May i.e. MAM) aerosol loading over BOB and IGP regions and the forthcoming monsoon rainfall have been observed from the thorough analysis of the fifteen years (1997-2011) monthly Total Ozone Mapping Spectrometer (TOMS) Aerosol Index (AI) and All-India Summer Monsoon Rainfall (AISMR) data. Composite analysis revealed that AI anomalies during pre-monsoon season are negative for excess year and positive for deficient monsoon years over the Indian subcontinent, with strong variation over Bay of Bengal (BOB) and Indo-Gangetic Plain (IGP) regions from the month of March onwards. The correlation coefficients between AISMR and pre-monsoon AI over BOB and IGP regions are found to be negative and significant at 5% level. The study clearly brings out that the pre-monsoon aerosol loading over the BOB and IGP regions has a significant correlational link with the forthcoming monsoon intensity; however a further study of the aerosol properties and their feedback to the cloud microphysical properties is asked for establishing their causal linkage.

Western Disturbances: A review

NASA Astrophysics Data System (ADS)

Dimri, A. P.; Niyogi, D.; Barros, A. P.; Ridley, J.; Mohanty, U. C.; Yasunari, T.; Sikka, D. R.

2015-06-01

Cyclonic storms associated with the midlatitude Subtropical Westerly Jet (SWJ), referred to as Western Disturbances (WDs), play a critical role in the meteorology of the Indian subcontinent. WDs embedded in the southward propagating SWJ produce extreme precipitation over northern India and are further enhanced over the Himalayas due to orographic land-atmosphere interactions. During December, January, and February, WD snowfall is the dominant precipitation input to establish and sustain regional snowpack, replenishing regional water resources. Spring melt is the major source of runoff to northern Indian rivers and can be linked to important hydrologic processes from aquifer recharge to flashfloods. Understanding the dynamical structure, evolution-decay, and interaction of WDs with the Himalayas is therefore necessary to improve knowledge which has wide ranging socioeconomic implications beyond short-term disaster response including cold season agricultural activities, management of water resources, and development of vulnerability-adaptive measures. In addition, WD wintertime precipitation provides critical mass input to existing glaciers and modulates the albedo characteristics of the Himalayas and Tibetan Plateau, affecting large-scale circulation and the onset of the succeeding Indian Summer Monsoon. Assessing the impacts of climate variability and change on the Indian subcontinent requires fundamental understanding of the dynamics of WDs. In particular, projected changes in the structure of the SWJ will influence evolution-decay processes of the WDs and impact Himalayan regional water availability. This review synthesizes past research on WDs with a perspective to provide a comprehensive assessment of the state of knowledge to assist both researchers and policymakers, and context for future research.

Potential use of random amplified polymorphic DNA (RAPD) technique to study the genetic diversity in Indian mustard (Brassica juncea) and its relationship to heterosis.

PubMed

Jain, A; Bhatia, S; Banga, S S; Prakash, S; Lakshmikumaran, M

1994-04-01

RAPD assays were performed, using 34 arbitrary decamer oligonucleotide primers and six combinations of two primers, to detect inherent variations and genetic relationships among 12 Indian and 11 exotic B. juncea genotypes. Of 595 amplification products identified, 500 of them were polymorphic across all genotypes. A low level of genetic variability was detected among the Indian genotypes, while considerable polymorphism was present among the exotic ones. Based on the pair-wise comparisons of amplification products the genetic similarity was calculated using Jaccard's similarity coefficients and a dendrogram was constructed using an unweighted pair group method was arithmetical averages (UPGMA). On the basis of this analysis the genotypes were clustered into two groups, A and B. Group A comprised only exotic genotypes, whereas all the Indian genotypes and four of the exotic genotypes were clustered in group B. Almost similar genotypic rankings could also be established by computing as few as 200 amplification products. In general, a high per cent of heterosis was recorded in crosses involving Indian x exotic genotypes. On the other hand, when crosses were made amongst Indian or exotic genotypes, about 80% of them exhibited negative heterosis. Results from this study indicate that, despite the lack of direct correlation between the genetic distance and the degree of heterosis, genetic diversity forms a very useful guide not only for investigating the relationships among Brassica genotypes but also in the selection of parents for heterotic hybrid combinations.

American Indian History and Writing from Home: Constructing an Indian Perspective

ERIC Educational Resources Information Center

Fixico, Donald L.

2009-01-01

If the typical premise of American Indian history is actually the history of Indian-white relations, then the "other" side of the coin must be turned over for understanding an Indian point of view and what is called "writing from home." Conceptually, "writing from home" is the challenge of historians who are American Indian and who write history…

Indianization of psychiatry utilizing Indian mental concepts

PubMed Central

Avasthi, Ajit; Kate, Natasha; Grover, Sandeep

2013-01-01

Most of the psychiatry practice in India is guided by the western concepts of mental health and illness, which have largely ignored the role of religion, family, eastern philosophy, and medicine in understanding and managing the psychiatric disorders. India comprises of diverse cultures, languages, ethnicities, and religious affiliations. However, besides these diversities, there are certain commonalities, which include Hinduism as a religion which is spread across the country, the traditional family system, ancient Indian system of medicine and emphasis on use of traditional methods like Yoga and Meditation for controlling mind. This article discusses as to how mind and mental health are understood from the point of view of Hinduism, Indian traditions and Indian systems of medicine. Further, the article focuses on as to how these Indian concepts can be incorporated in the practice of contemporary psychiatry. PMID:23858244

Chromosome Numbers and Genome Size Variation in Indian Species of Curcuma (Zingiberaceae)

PubMed Central

Leong-Škorničková, Jana; Šída, Otakar; Jarolímová, Vlasta; Sabu, Mamyil; Fér, Tomáš; Trávníček, Pavel; Suda, Jan

2007-01-01

Background and Aims Genome size and chromosome numbers are important cytological characters that significantly influence various organismal traits. However, geographical representation of these data is seriously unbalanced, with tropical and subtropical regions being largely neglected. In the present study, an investigation was made of chromosomal and genome size variation in the majority of Curcuma species from the Indian subcontinent, and an assessment was made of the value of these data for taxonomic purposes. Methods Genome size of 161 homogeneously cultivated plant samples classified into 51 taxonomic entities was determined by propidium iodide flow cytometry. Chromosome numbers were counted in actively growing root tips using conventional rapid squash techniques. Key Results Six different chromosome counts (2n = 22, 42, 63, >70, 77 and 105) were found, the last two representing new generic records. The 2C-values varied from 1·66 pg in C. vamana to 4·76 pg in C. oligantha, representing a 2·87-fold range. Three groups of taxa with significantly different homoploid genome sizes (Cx-values) and distinct geographical distribution were identified. Five species exhibited intraspecific variation in nuclear DNA content, reaching up to 15·1 % in cultivated C. longa. Chromosome counts and genome sizes of three Curcuma-like species (Hitchenia caulina, Kaempferia scaposa and Paracautleya bhatii) corresponded well with typical hexaploid (2n = 6x = 42) Curcuma spp. Conclusions The basic chromosome number in the majority of Indian taxa (belonging to subgenus Curcuma) is x = 7; published counts correspond to 6x, 9x, 11x, 12x and 15x ploidy levels. Only a few species-specific C-values were found, but karyological and/or flow cytometric data may support taxonomic decisions in some species alliances with morphological similarities. Close evolutionary relationships among some cytotypes are suggested based on the similarity in homoploid genome sizes and geographical grouping

Relation Between the Rainfall and Soil Moisture During Different Phases of Indian Monsoon

NASA Astrophysics Data System (ADS)

Varikoden, Hamza; Revadekar, J. V.

2018-03-01

Soil moisture is a key parameter in the prediction of southwest monsoon rainfall, hydrological modelling, and many other environmental studies. The studies on relationship between the soil moisture and rainfall in the Indian subcontinent are very limited; hence, the present study focuses the association between rainfall and soil moisture during different monsoon seasons. The soil moisture data used for this study are the ESA (European Space Agency) merged product derived from four passive and two active microwave sensors spanning over the period 1979-2013. The rainfall data used are India Meteorological Department gridded daily data. Both of these data sets are having a spatial resolution of 0.25° latitude-longitude grid. The study revealed that the soil moisture is higher during the southwest monsoon period similar to rainfall and during the pre-monsoon period, the soil moisture is lower. The annual cycle of both the soil moisture and rainfall has the similitude of monomodal variation with a peak during the month of August. The interannual variability of soil moisture and rainfall shows that they are linearly related with each other, even though they are not matched exactly for individual years. The study of extremes also exhibits the surplus amount of soil moisture during wet monsoon years and also the regions of surplus soil moisture are well coherent with the areas of high rainfall.

MAGSAT project

NASA Technical Reports Server (NTRS)

1981-01-01

Programs for the conversion of MAGSAT tapes (both CHRONICLE and CHRONINT formats) from IBM binary to DEC 10 binary were developed in ASSEMBLY language) and programs for selection of only a particular part of CHRONICLE tape (e.g., passes over the Indian subcontinent) were also prepared. Data on a few selected quiet and disturbed days were studied by substracting the main field, and the anomalies over the Indian region were partly identified on few of the passes. A national Workshop on MAGSAT was arranged. The potentialities and usefulness of MAGSAT data particularly in the study of crustal lithology was discussed.

The Horse and the Plains Indian. Indian Culture Series.

ERIC Educational Resources Information Center

Schuessler, Raymond

Produced by the Montana Council for Indian Education as part of its Indian Culture Series, the five short articles in the book explain how the Plains Indians got horses in legend and in fact. The stories describe the behavior codes, rules, cultural and social significance, and eventual cessation of horse raids, and the ceremony and tradition…

Resisting the Script of Indian Education: Zitkala Sa and the Carlisle Indian School.

ERIC Educational Resources Information Center

Enoch, Jessica

2002-01-01

Offers a "definition" of Zitkala Sa as an Indian teacher who, at the turn of the 20th century, challenged and countered educational norms that silenced Indian voices and erased Indian culture. Examines her autobiographical essays, "Impressions of an Indian Childhood,""The School Days of an Indian Girl," and "An…

Evolution of Indian land surface biases in the seasonal hindcasts from the Met Office Global Seasonal Forecasting System GloSea5

NASA Astrophysics Data System (ADS)

Chevuturi, Amulya; Turner, Andrew G.; Woolnoug, Steve J.; Martin, Gill

2017-04-01

In this study we investigate the development of biases over the Indian region in summer hindcasts of the UK Met Office coupled initialised global seasonal forecasting system, GloSea5-GC2. Previous work has demonstrated the rapid evolution of strong monsoon circulation biases over India from seasonal forecasts initialised in early May, together with coupled strong easterly wind biases on the equator. These mean state biases lead to strong precipitation errors during the monsoon over the subcontinent. We analyse a set of three springtime start dates for the 20-year hindcast period (1992-2011) and fifteen total ensemble members for each year. We use comparisons with variety of observations to assess the evolution of the mean state biases over the Indian land surface. All biases within the model develop rapidly, particularly surface heat and radiation flux biases. Strong biases are present within the model climatology from pre-monsoon (May) in the surface heat fluxes over India (higher sensible / lower latent heat fluxes) when compared to observed estimates. The early evolution of such biases prior to onset rains suggests possible problems with the land surface scheme or soil moisture errors. Further analysis of soil moisture over the Indian land surface shows a dry bias present from the beginning of the hindcasts during the pre-monsoon. This lasts until the after the monsoon develops (July) after which there is a wet bias over the region. Soil moisture used for initialization of the model also shows a dry bias when compared against the observed estimates, which may lead to the same in the model. The early dry bias in the model may reduce local moisture availability through surface evaporation and thus may possibly limit precipitation recycling. On this premise, we identify and test the sensitivity of the monsoon in the model against higher soil moisture forcing. We run sensitivity experiments initiated using gridpoint-wise annual soil moisture maxima over the Indian

Tree seed traits' response to monsoon climate and altitude in Indian subcontinent with particular reference to the Himalayas.

PubMed

Singh, Surendra P; Phartyal, Shyam S; Rosbakh, Sergey

2017-09-01

Seed traits are related to several ecological attributes of a plant species, including its distribution. While the storage physiology of desiccation-sensitive seeds has drawn considerable attention, their ecology has remained sidelined, particularly how the strong seasonality of precipitation in monsoonal climate affects their temporal and spatial distribution. We compiled data on seed mass, seed desiccation behavior, seed shedding, and germination periodicity in relation to monsoon and altitude for 198 native tree species of Indian Himalayas and adjoining plains to find out (1) the adaptive significance of seed mass and seed desiccation behavior in relation to monsoon and (2) the pattern of change in seed mass in relation to altitude, habitat moisture, and succession. The tree species fall into three categories with respect to seed shedding and germination periodicities: (1) species in which both seed shedding and germination are synchronized with monsoon, referred to as monsoon-synchronized (MS, 46 species); (2) species in which seed germination is synchronized with monsoon, but seeds are shed several months before monsoon, referred to as partially monsoon-synchronized (PMS, 112 species); and (3) species in which both shedding and germination occur outside of monsoon months, referred to as monsoon-desynchronized (MD, 39 species). The seed mass of MS species (1,718 mg/seed) was greater than that of PMS (627 mg/seed) and MD (1,144 mg/seed). Of the 40 species with desiccation-sensitive seeds, 45% belong to the MS category, almost similar (approx. 47%) to woody plants with desiccation-sensitive seeds in evergreen rain forests. Seed mass differed significantly as per seed desiccation behavior and successional stage. No relationship of seed mass was found with altitude alone and on the basis of seed desiccation behavior. However, seed mass trend along the altitude differed among monsoon synchronization strategies. Based on our findings, we conclude that in the

Restructuring an undergraduate dental curriculum to global standards--a case study in an Indian dental school.

PubMed

Kadagad, P; Tekian, A; Pinto, P X; Jirge, V L

2012-05-01

Globalisation has affected all aspects of life and dentistry is no exception. In the context of today's dentist being a global citizen, undergraduate training in dentistry is set to ensure converging standards so that international recognition of dental qualifications can move forward. The decision of the Dental Council of India to expand the undergraduate dental program to five years provides an opportunity to be part of the endeavor of the Global Dental Congress to achieve converging standards which was initially for the European Union, and now spreading out globally. Economic emergence in Indian subcontinent has resulted in growing oral health care needs both in quality and quantity. To address this issue, the graduating dentist needs to be trained following a competency based curricular model. Access to Internet facilitated the goal of achieving converging standards of dental schools to be feasible because of the instant communication and capacity to share information about training strategies via technology across the globe. Upgrading the undergraduate training to global standards by dental schools in India could be a wise and strategic move both for attracting students to study in India, as well as retaining the graduates after their training. The following is a case study of an Indian dental school set to restructure the undergraduate curriculum to global standards using the 8 steps of Kotter's transformational change. Change in curriculum and the subsequent accreditation of the school in global platform not only attracts prospective students but also results in producing competent dentists. Dental education provided by the institution can result in quality assurance, benchmarking the assessment system to achieve international recognition. This paper highlights the need and importance of facilitation of international convergence with long term aspirations for mutual recognition of international degrees. © 2011 John Wiley & Sons A/S.

Molecular characterization and phylogenetic analysis of Explanatum explanatum in India based on nucleotide sequences of ribosomal ITS2 and the mitochondrial gene nad1.

PubMed

Hayashi, Kei; Mohanta, Uday K; Ohari, Yuma; Neeraja, Tambireddy; Singh, T Shantikumar; Sugiyama, Hiromu; Itagaki, Tadashi

2016-12-01

The aim of this study was to analyze the phylogenetic relationship between Explanatum explanatum populations in India and other countries of the Indian subcontinent. Seventy liver amphistomes collected from four localities in India were identified as E. explanatum based on the nucleotide sequences of ribosomal ITS2. The flukes were then analyzed phylogenetically based on the nucleotide sequence of the mitochondrial gene nad1 in comparison with flukes from Bangladesh and Nepal. In the resulting phylogenetic tree, the nad1 haplotypes from India were divided into four clades, and the flukes showing the haplotypes of clades A and C were predominant in India. The haplotypes of the clades A and C have also been detected in Bangladesh and Nepal, and therefore, it seems they occur commonly throughout the Indian subcontinent. The results of AMOVA suggested that gene flow was likely to occur between E. explanatum populations in these countries. These countries are geographically close and have been historically and culturally connected to each other, and therefore, the movements of host ruminants among these countries might have been involved in the migration of the flukes and their gene flow.

Cluster-cluster clustering

NASA Technical Reports Server (NTRS)

Barnes, J.; Dekel, A.; Efstathiou, G.; Frenk, C. S.

1985-01-01

The cluster correlation function xi sub c(r) is compared with the particle correlation function, xi(r) in cosmological N-body simulations with a wide range of initial conditions. The experiments include scale-free initial conditions, pancake models with a coherence length in the initial density field, and hybrid models. Three N-body techniques and two cluster-finding algorithms are used. In scale-free models with white noise initial conditions, xi sub c and xi are essentially identical. In scale-free models with more power on large scales, it is found that the amplitude of xi sub c increases with cluster richness; in this case the clusters give a biased estimate of the particle correlations. In the pancake and hybrid models (with n = 0 or 1), xi sub c is steeper than xi, but the cluster correlation length exceeds that of the points by less than a factor of 2, independent of cluster richness. Thus the high amplitude of xi sub c found in studies of rich clusters of galaxies is inconsistent with white noise and pancake models and may indicate a primordial fluctuation spectrum with substantial power on large scales.

Assessment of genetic diversity, population structure and relationships in Indian and non-Indian genotypes of finger millet (Eleusine coracana (L.) Gaertn) using genomic SSR markers.

PubMed

Ramakrishnan, M; Antony Ceasar, S; Duraipandiyan, V; Al-Dhabi, N A; Ignacimuthu, S

2016-01-01

We evaluated the genetic variation and population structure in Indian and non-Indian genotypes of finger millet using 87 genomic SSR primers. The 128 finger millet genotypes were collected and genomic DNA was isolated. Eighty-seven genomic SSR primers with 60-70 % GC contents were used for PCR analysis of 128 finger millet genotypes. The PCR products were separated and visualized on a 6 % polyacrylamide gel followed by silver staining. The data were used to estimate major allele frequency using Power Marker v3.0. Dendrograms were constructed based on the Jaccard's similarity coefficient. Statistical fitness and population structure analyses were performed to find the genetic diversity. The mean major allele frequency was 0.92; the means of polymorphic alleles were 2.13 per primer and 1.45 per genotype; the average polymorphism was 59.94 % per primer and average PIC value was 0.44 per primer. Indian genotypes produced an additional 0.21 allele than non-Indian genotypes. Gene diversity was in the range from 0.02 to 0.35. The average heterozygosity was 0.11, close to 100 % homozygosity. The highest inbreeding coefficient was observed with SSR marker UGEP67. The Jaccard's similarity coefficient value ranged from 0.011 to 0.836. The highest similarity value was 0.836 between genotypes DPI009-04 and GPU-45. Indian genotypes were placed in Eleusine coracana major cluster (EcMC) 1 along with 6 non-Indian genotypes. AMOVA showed that molecular variance in genotypes from various geographical regions was 4 %; among populations it was 3 % and within populations it was 93 %. PCA scatter plot analysis showed that GPU-28, GPU-45 and DPI009-04 were closely dispersed in first component axis. In structural analysis, the genotypes were divided into three subpopulations (SP1, SP2 and SP3). All the three subpopulations had an admixture of alleles and no pure line was observed. These analyses confirmed that all the genotypes were genetically diverse and had been grouped based on

Indian Craniometric Variability and Affinities

PubMed Central

Raghavan, Pathmanathan; Bulbeck, David; Pathmanathan, Gayathiri; Rathee, Suresh Kanta

2013-01-01

Recently published craniometric and genetic studies indicate a predominantly indigenous ancestry of Indian populations. We address this issue with a fuller coverage of Indian craniometrics than any done before. We analyse metrical variability within Indian series, Indians' sexual dimorphism, differences between northern and southern Indians, index-based differences of Indian males from other series, and Indians' multivariate affinities. The relationship between a variable's magnitude and its variability is log-linear. This relationship is strengthened by excluding cranial fractions and series with a sample size less than 30. Male crania are typically larger than female crania, but there are also shape differences. Northern Indians differ from southern Indians in various features including narrower orbits and less pronounced medial protrusion of the orbits. Indians resemble Veddas in having small crania and similar cranial shape. Indians' wider geographic affinities lie with “Caucasoid” populations to the northwest, particularly affecting northern Indians. The latter finding is confirmed from shape-based Mahalanobis-D distances calculated for the best sampled male and female series. Demonstration of a distinctive South Asian craniometric profile and the intermediate status of northern Indians between southern Indians and populations northwest of India confirm the predominantly indigenous ancestry of northern and especially southern Indians. PMID:24455409

Experiences Recruiting Indian Worksites for an Integrated Health Protection and Health Promotion Randomized Control Trial in Maharashtra, India

ERIC Educational Resources Information Center

Shulman Cordeira, L.; Pednekar, M. S.; Nagler, E. M.; Gautam, J.; Wallace, L.; Stoddard, A. M.; Gupta, P. C.; Sorensen, G. C.

2015-01-01

This article provides an overview of the recruitment strategies utilized in the Mumbai Worksites Tobacco Control Study, a cluster randomized trial testing the effectiveness of an integrated tobacco control and occupational safety and health program in Indian manufacturing worksites. From June 2012 to June 2013, 20 companies were recruited.…

Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent maternal gene flow in Indian population groups.

PubMed

Sharma, Swarkar; Saha, Anjana; Rai, Ekta; Bhat, Audesh; Bamezai, Ramesh

2005-01-01

We have analysed the hypervariable regions (HVR I and II) of human mitochondrial DNA (mtDNA) in individuals from Uttar Pradesh (UP), Bihar (BI) and Punjab (PUNJ), belonging to the Indo-European linguistic group, and from South India (SI), that have their linguistic roots in Dravidian language. Our analysis revealed the presence of known and novel mutations in both hypervariable regions in the studied population groups. Median joining network analyses based on mtDNA showed extensive overlap in mtDNA lineages despite the extensive cultural and linguistic diversity. MDS plot analysis based on Fst distances suggested increased maternal genetic proximity for the studied population groups compared with other world populations. Mismatch distribution curves, respective neighbour joining trees and other statistical analyses showed that there were significant expansions. The study revealed an ancient common ancestry for the studied population groups, most probably through common founder female lineage(s), and also indicated that human migrations occurred (maybe across and within the Indian subcontinent) even after the initial phase of female migration to India.

Laparoscopic management of CBD stones: an Indian experience.

PubMed

Chander, Jagdish; Vindal, Anubhav; Lal, Pawanindra; Gupta, Nikhil; Ramteke, Vinod Kumar

2011-01-01

Common bile duct stones (CBDS) that are seen in the Asian population are very different from those seen in the west. It is not infrequent to see multiple, large, and impacted stones and a hugely dilated CBD. Many of these patients have been managed by open CBD exploration (OCBDE), even after the advent of laparoscopic cholecystectomy (LC), because these large stones pose significant challenges for extraction by endoscopic retrograde cholangiopancreatography. This series presents the largest experience of managing CBDS using a laparoscopic approach from Indian subcontinent. Between 2003 and 2009, 150 patients with documented CBDS were treated laparoscopically at a tertiary care hospital in New Delhi. Of these, 4 patients were managed through transcystic route and 140 through the transcholedochal route. There were 34 men and 116 women patients with age ranging from 15 to 72 years. The mean size of the CBD on ultrasound was 11.7 ± 3.7 mm and on MRCP 13.8 ± 4.7 mm. The number of stones extracted varied from 1 to 70 and the size of the extracted stones from 5 to 30 mm. The average duration of surgery was 139.9 ± 26.3 min and the mean intraoperative blood loss was 103.4 ± 85.9 ml. There were 6 conversions to open procedures, 1 postoperative death (0.7%), and 23 patients (15%) had nonfatal postoperative complications. Three patients had retained stones (2%) and one developed recurrent stone (0.7%). Even in patients with multiple, large, and impacted CBDS, there is scope for a minimally invasive procedure with its attendant benefits in the form of laparoscopic CBD exploration (LCBDE).

A deep structural ridge beneath central India

NASA Astrophysics Data System (ADS)

Agrawal, P. K.; Thakur, N. K.; Negi, J. G.

A joint-inversion of magnetic satellite (MAGSAT) and free air gravity data has been conducted to quantitatively investigate the cause for Bouguer gravity anomaly over Central Indian plateaus and possible fold consequences beside Himalayan zone in the Indian sub-continent due to collision between Indian and Eurasian plates. The appropriate inversion with 40 km crustal depth model has delineated after discriminating high density and magnetisation models, for the first time, about 1500 km long hidden ridge structure trending NW-SE. The structure is parallel to Himalayan fold axis and the Indian Ocean ridge in the Arabian Sea. A quantitative relief model across a representative anomaly profile confirms the ridge structure with its highest point nearly 6 km higher than the surrounding crustal level in peninsular India. The ridge structure finds visible support from the astro-geoidal contours.

Modern Indian Psychology. Revised Edition.

ERIC Educational Resources Information Center

Bryde, John F.

Written on the basis of senior Indian verbal relatings collected over a 23-year span, this revised edition on modern Indian psychology incorporates suggestions from Indian students and their teachers, Indian and non-Indian social studies experts, and other Indian people. The book contains 6 major divisions: (1) "Culture and Indian…

Migrants of the Information Age: Indian and Mexican Engineers and Regional Development in Silicon Valley. Working Paper No. 16.

ERIC Educational Resources Information Center

Alarcon, Rafael

Immigration and domestic industrial policies have been powerful instruments in the creation of immigrant "niches" in labor markets. While Indians have clustered in the information technology industry, Mexicans have formed niches in low-skilled industries such as agriculture. A review of the relationship between immigration policy and the…

Lyra

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

(the Lyre; abbrev. Lyr, gen. Lyrae; area 286 sq. deg.) A northern constellation which lies between Hercules and Cygnus, and culminates at midnight in early July. It is an ancient constellation pattern, which was associated with an eagle or vulture in the Indian subcontinent and Arab countries, and with the mythical lyre invented by Hermes and given by Apollo to Orpheus in ancient Greece. Its brig...

Typhoid fever in the United States, 1999-2006.

PubMed

Lynch, Michael F; Blanton, Elizabeth M; Bulens, Sandra; Polyak, Christina; Vojdani, Jazmin; Stevenson, Jennifer; Medalla, Felicia; Barzilay, Ezra; Joyce, Kevin; Barrett, Timothy; Mintz, Eric Daniel

2009-08-26

Typhoid fever in the United States has increasingly been due to infection with antimicrobial-resistant Salmonella ser Typhi. National surveillance for typhoid fever can inform prevention and treatment recommendations. To assess trends in infections with antimicrobial-resistant S. Typhi. Cross-sectional, laboratory-based surveillance study. We reviewed data from 1999-2006 for 1902 persons with typhoid fever who had epidemiologic information submitted to the Centers for Disease Control and Prevention (CDC) and 2016 S. Typhi isolates sent by participating public health laboratories to the National Antimicrobial Resistance Monitoring System Laboratory at the CDC for antimicrobial susceptibility testing. Proportion of S. Typhi isolates demonstrating resistance to 14 antimicrobial agents and patient risk factors for antimicrobial-resistant infections. Patient median age was 22 years (range, <1-90 years); 1295 (73%) were hospitalized and 3 (0.2%) died. Foreign travel within 30 days of illness was reported by 1439 (79%). Only 58 travelers (5%) had received typhoid vaccine. Two hundred seventy-two (13%) of 2016 isolates tested were resistant to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole (multidrug-resistant S. Typhi [MDRST]); 758 (38%) were resistant to nalidixic acid (nalidixic acid-resistant S. Typhi [NARST]) and 734 NARST isolates (97%) had decreased susceptibility to ciprofloxacin. The proportion of NARST increased from 19% in 1999 to 54% in 2006. Five ciprofloxacin-resistant isolates were identified. Patients with resistant infections were more likely to report travel to the Indian subcontinent: 85% of patients infected with MDRST and 94% with NARST traveled to the Indian subcontinent, while 44% of those with susceptible infections did (MDRST odds ratio, 7.5; 95% confidence interval, 4.1-13.8; NARST odds ratio, 20.4; 95% confidence interval, 12.4-33.9). Infection with antimicrobial-resistant S. Typhi strains among US patients with typhoid fever is

Previous exposure in a high-risk area for travellers' diarrhoea within the past year is associated with a significant protective effect for travellers' diarrhoea: a prospective observational cohort study in travellers to South Asia.

PubMed

Kuenzli, Esther; Juergensen, David; Kling, Kerstin; Jaeger, Veronika K; DeCrom, Susan; Steffen, Robert; Widmer, Andreas F; Battegay, Manuel; Hatz, Christoph; Neumayr, Andreas

2017-09-01

Travellers' diarrhoea is the most common health problem in travellers. Depending on the region visited, up to 40% of travellers develop diarrhoea during a 2-week trip. The aim of this study was to assess risk factors for TD among travellers to the Indian subcontinent. An observational prospective multicentre cohort study investigated travellers to the Indian subcontinent. Participants completed questionnaires assessing the incidence of travellers' diarrhoea and identifying potential risk factors. Covariates were assessed univariately, followed by a multivariate regression. Two-hundred and twenty-six travellers were enrolled into the study, 178 filled in both pre- and post-travel questionnaires. Overall, the attack rate of travellers' diarrhoea was 38.2%. Travel destination is a key risk factor for the occurrence of TD. Travelling to India or Nepal vs Bhutan is associated with an increased risk for TD (OR 6.68 and 6.62, respectively). A length of stay of more than 3 weeks compared to less than 2 weeks is also associated with a significantly increased risk (OR 5.45). Having stayed in a high-risk area for travellers' diarrhoea within the past year before the current trip is associated with a significantly decreased risk (OR 0.19). No association was found between consumption of high risk food (i.e. tap water, ice cream, raw meat and hamburgers) and travellers' diarrhoea. Travellers' diarrhoea is a frequent problem in travellers to the Indian subcontinent. Previous exposure in a high-risk area for travellers' diarrhoea within the past year appears to have a significant protective effect. Furthermore, an association between the occurrence of travellers' diarrhoea and travel destination and length of stay, respectively, was observed. Consumption of risk food did not confer a TD risk in our study. © International Society of Travel Medicine, 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

The Holocene Indian Summer Monsoon Variability Recorded in a Stalagmite From NE India.

NASA Astrophysics Data System (ADS)

Breitenbach, S.; Plessen, B.; Oberhänsli, H.; Marwan, N.; Lund, D.; Adkins, J.; Günther, D.; Fricker, M.; Haug, G.

2007-12-01

South Asian economies depend on the timely onset of the Indian Summer Monsoon (ISM), but understanding of the ISM variability is incomplete, due to lack of information on past ISM. Our stalagmite is the first well-dated climate record from the heart of the ISM region spanning the past 11,000 years. The speleothem was collected from Krem Umsynrang Cave, located 825 m above sea level in NE India. This region is influenced by the ISM, with more than 75% of annual rainfall falling during the monsoon season. The chronology of the stalagmite is based on 36 U/Th multi-collector ICP MS dates. Our data reveal profound changes in ISM rainfall and moisture balance. A strong increase of the ISM between 11.4 and 9.3 kyr BP is followed by a gradual decline over the course of the Holocene. This may be best explained by a strong coupling between ISM and the Intertropical Convergence Zone (ITCZ), with a stronger ISM during a more northerly position of the ITCZ. This long-term trend is punctuated by centennial to multi- to sub-decadal events of a weaker ISM. The most pronounced events occurred at 10.7, 8.5-8.1, 7.4, 4.4-4.0, 3.5, 1.4, 0.3 kyr BP. The δ13C record is interpreted to reflect centennial to decadal changes in the drip rate of the stalagmite. δ13C fractionation during periods of higher drip rates (i.e. times of longer residence time of percolating water) correspond with periods of a weaker ISM as inferred from our δ18O record. Our record shows in great detail periods of weaker ISM. They provide new insights on the sensitivity of terrestrial climate archives on the Indian subcontinent. Drought events recorded in our stalagmite correspond well with intervals of severe aridity known from other regions of the Asian monsoon. Moreover, our 11,000 year climate record shows that NE India experienced its driest conditions during the last three millennia.

Cooperative Agreements in Indian Education. Indian Education Legal Support Project: "Tribalizing Indian Education."

ERIC Educational Resources Information Center

McCoy, Melody

The Indian Education Legal Support Project emphasizes the legal rights of tribes to control the formal education of their members. The project's work includes developing tribal education laws and reforming state and national Indian education legislation. This document compiles 10 voluntary cooperative agreements among federal, public, and tribal…

Molecular spectrum of c-KIT and PDGFRA gene mutations in gastro intestinal stromal tumor: determination of frequency, distribution pattern and identification of novel mutations in Indian patients.

PubMed

Ahmad, Firoz; Lad, Purnima; Bhatia, Simi; Das, Bibhu Ranjan

2015-01-01

KIT and PDGFRA gene mutations are the major genetic alterations seen in gastrointestinal stromal tumors (GISTs) and are being used clinically for predicting response to imatinib therapy. In the current study, we set out to explore the frequency and distribution pattern of c-KIT (exons 9, 11 and 13) and PDGFRA (exons 12 and 18) by direct sequencing in a series of 70 Indian GIST cases. Overall, 27 (38.5 %) and 4 (5.7 %) of the cases had c-KIT and PDGFRA mutations, respectively. Majority of KIT mutations involved exon 11 (85.7 %), followed by exon 9 (14.3 %), while none showed exon 13 mutation. Most exon 9 mutations showed Ala503-Tyr504 duplication, while one had novel point mutation at codon 476 (S476G). In contrast to exon 9 mutations, most exon 11 mutations were in-frame deletions (79 %, 19/24), predominantly at codons 550-560, while remaining exon 11 mutant cases were point mutations at codons 559, 560, 568, 573 and 575. Interestingly, P573T, Q556_V560delinsH, Q575H and Q575_P577 were novel variations observed in exon 11. The PDGFRA mutations were seen mostly in exon 18, which showed point mutation at codon 842 (D842V), while exon 12 showed a novel indel variation (V561_H570delinsT). No significant correlation between c-KIT/PDGFRA mutations and clinicopathological data was observed. In conclusion, this study highlights the frequency and distribution pattern of c-KIT/PDGFRA mutation in Indian cohort. The current study identified novel variations that added new insights into the genetic heterogeneity of GIST patients. Furthermore, this is the first study to report the presence of PDGFRA mutation from Indian subcontinent.

78 FR 15738 - Indian Gaming

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2013-03-12

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under Section 11 of the Indian Gaming...

American Indian Issues in Higher Education. Contemporary American Indian Issues Series, No. 3.

ERIC Educational Resources Information Center

California Univ., Los Angeles. American Indian Studies Center.

A collection of 17 articles on American Indian issues in higher education contains Russell Thornton's introduction, "American Indian Studies as an Academic Discipline: A Revisit," plus five major sections. "Purpose of American Indian Studies" covers relevancy of Indian Studies in higher education (Duchene); an alternative model…

76 FR 11258 - Indian Gaming

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2011-03-01

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under Section 11 of the Indian...

76 FR 49505 - Indian Gaming

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2011-08-10

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under Section 11 of the Indian...

75 FR 68823 - Indian Gaming

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2010-11-09

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... and the Siletz Indians of Oregon. DATES: Effective Date: November 9, 2010. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary...

76 FR 42722 - Indian Gaming

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2011-07-19

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Date: July 19, 2011. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Assistant Secretary--Indian Affairs, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY...

78 FR 11221 - Indian Gaming

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2013-02-15

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming...

77 FR 41200 - Indian Gaming

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2012-07-12

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... and the Federated Indians of Graton Rancheria. DATES: Effective Date: July 12, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant...

76 FR 56466 - Indian Gaming

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2011-09-13

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian...

77 FR 5566 - Indian Gaming

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2012-02-03

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming...

76 FR 8375 - Indian Gaming

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2011-02-14

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming...

75 FR 38833 - Indian Gaming

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2010-07-06

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Date: July 6, 2010. FOR FURTHER INFORMATION CONTACT: Paula Hart, Director, Office of Indian Gaming...) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

76 FR 49505 - Indian Gaming

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2011-08-10

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming...

78 FR 17427 - Indian Gaming

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2013-03-21

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian...

77 FR 59641 - Indian Gaming

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2012-09-28

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Indian Gaming, Office of the Deputy Assistant Secretary--Policy and Economic Development, Washington, DC 20240, (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act...

76 FR 35221 - Epidemiology Program for American Indian/Alaska Native Tribes and Urban Indian Communities...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service Epidemiology Program for American Indian/Alaska Native Tribes and Urban Indian Communities; Correction AGENCY: Indian Health Service, HHS. ACTION: Notice; correction. SUMMARY: The Indian Health Service published a document in the Federal...

75 FR 38834 - Indian Gaming

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2010-07-06

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: July 6, 2010. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office...-4066. SUPPLEMENTARY INFORMATION: Under Section 11 of the Indian Gaming Regulatory Act of 1988 (IGRA...

76 FR 52968 - Indian Gaming

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2011-08-24

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: Effective Date: August 24, 2011. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian..., (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

75 FR 61511 - Indian Gaming

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2010-10-05

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs.... FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the.... SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988 (IGRA), Public Law 100...

78 FR 44146 - Indian Gaming

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2013-07-23

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Miwok Indians and the State of California taking effect. DATES: Effective Date: July 23, 2013. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy...

78 FR 10203 - Indian Gaming

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2013-02-13

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Rocky Boy's Indian Reservation and the State of Montana. DATES: Effective Date: February 13, 2013. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy...

77 FR 30550 - Indian Gaming

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2012-05-23

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Indian Tribe and the State of Nevada. DATES: Effective Date: May 23, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary...

78 FR 33435 - Indian Gaming

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2013-06-04

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Pima- Maricopa Indian Community and the State of Arizona (Amendment). DATES: Effective Date: June 4, 2013. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...

77 FR 45371 - Indian Gaming

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2012-07-31

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Date: July 31, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming...) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

75 FR 61511 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: Effective Date: October 5, 2010. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian..., (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

76 FR 33341 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: Effective Date: June 8, 2011. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian..., (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

75 FR 55823 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... Date: September 14, 2010. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian..., (202) 219-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988...

76 FR 165 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-03

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... approval of the 2010 Amendments to the Menominee Indian Tribe of Wisconsin (``Tribe'') and the State of.... FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...

75 FR 68618 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-08

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., 2010. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...-4066. SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988 (IGRA...

77 FR 76514 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... of California and the Coyote Valley Band of Pomo Indians. DATES: Effective Date: December 28, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...

Unravelling the Molecular Epidemiology and Genetic Diversity among Burkholderia pseudomallei Isolates from South India Using Multi-Locus Sequence Typing.

PubMed

Tellapragada, Chaitanya; Kamthan, Aayushi; Shaw, Tushar; Ke, Vandana; Kumar, Subodh; Bhat, Vinod; Mukhopadhyay, Chiranjay

2016-01-01

There is a slow but steady rise in the case detection rates of melioidosis from various parts of the Indian sub-continent in the past two decades. However, the epidemiology of the disease in India and the surrounding South Asian countries remains far from well elucidated. Multi-locus sequence typing (MLST) is a useful epidemiological tool to study the genetic relatedness of bacterial isolates both with-in and across the countries. With this background, we studied the molecular epidemiology of 32 Burkholderia pseudomallei isolates (31 clinical and 1 soil isolate) obtained during 2006-2015 from various parts of south India using multi-locus sequencing typing and analysis. Of the 32 isolates included in the analysis, 30 (93.7%) had novel allelic profiles that were not reported previously. Sequence type (ST) 1368 (n = 15, 46.8%) with allelic profile (1, 4, 6, 4, 1, 1, 3) was the most common genotype observed. We did not observe a genotypic association of STs with geographical location, type of infection and year of isolation in the present study. Measure of genetic differentiation (FST) between Indian and the rest of world isolates was 0.14413. Occurrence of the same ST across three adjacent states of south India suggest the dispersion of B.pseudomallei across the south western coastal part of India with limited geographical clustering. However, majority of the STs reported from the present study remained as "outliers" on the eBURST "Population snapshot", suggesting the genetic diversity of Indian isolates from the Australasian and Southeast Asian isolates.

Connectivity of Tiger (Panthera tigris) Populations in the Human-Influenced Forest Mosaic of Central India

PubMed Central

Joshi, Aditya; Vaidyanathan, Srinivas; Mondol, Samrat; Edgaonkar, Advait; Ramakrishnan, Uma

2013-01-01

Today, most wild tigers live in small, isolated Protected Areas within human dominated landscapes in the Indian subcontinent. Future survival of tigers depends on increasing local population size, as well as maintaining connectivity between populations. While significant conservation effort has been invested in increasing tiger population size, few initiatives have focused on landscape-level connectivity and on understanding the effect different landscape elements have on maintaining connectivity. We combined individual-based genetic and landscape ecology approaches to address this issue in six protected areas with varying tiger densities and separation in the Central Indian tiger landscape. We non-invasively sampled 55 tigers from different protected areas within this landscape. Maximum-likelihood and Bayesian genetic assignment tests indicate long-range tiger dispersal (on the order of 650 km) between protected areas. Further geo-spatial analyses revealed that tiger connectivity was affected by landscape elements such as human settlements, road density and host-population tiger density, but not by distance between populations. Our results elucidate the importance of landscape and habitat viability outside and between protected areas and provide a quantitative approach to test functionality of tiger corridors. We suggest future management strategies aim to minimize urban expansion between protected areas to maximize tiger connectivity. Achieving this goal in the context of ongoing urbanization and need to sustain current economic growth exerts enormous pressure on the remaining tiger habitats and emerges as a big challenge to conserve wild tigers in the Indian subcontinent. PMID:24223132

Connectivity of tiger (Panthera tigris) populations in the human-influenced forest mosaic of Central India.

PubMed

Joshi, Aditya; Vaidyanathan, Srinivas; Mondol, Samrat; Edgaonkar, Advait; Ramakrishnan, Uma

2013-01-01

Today, most wild tigers live in small, isolated Protected Areas within human dominated landscapes in the Indian subcontinent. Future survival of tigers depends on increasing local population size, as well as maintaining connectivity between populations. While significant conservation effort has been invested in increasing tiger population size, few initiatives have focused on landscape-level connectivity and on understanding the effect different landscape elements have on maintaining connectivity. We combined individual-based genetic and landscape ecology approaches to address this issue in six protected areas with varying tiger densities and separation in the Central Indian tiger landscape. We non-invasively sampled 55 tigers from different protected areas within this landscape. Maximum-likelihood and Bayesian genetic assignment tests indicate long-range tiger dispersal (on the order of 650 km) between protected areas. Further geo-spatial analyses revealed that tiger connectivity was affected by landscape elements such as human settlements, road density and host-population tiger density, but not by distance between populations. Our results elucidate the importance of landscape and habitat viability outside and between protected areas and provide a quantitative approach to test functionality of tiger corridors. We suggest future management strategies aim to minimize urban expansion between protected areas to maximize tiger connectivity. Achieving this goal in the context of ongoing urbanization and need to sustain current economic growth exerts enormous pressure on the remaining tiger habitats and emerges as a big challenge to conserve wild tigers in the Indian subcontinent.

77 FR 76513 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs..., 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the.... SUPPLEMENTARY INFORMATION: Under section 11 of the Indian Gaming Regulatory Act of 1988 (IGRA) Public Law 100...

75 FR 8108 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... approval of the Tribal-State Compact between the Pyramid Lake Paiute Indian Tribe and the State of Nevada... L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and...

American Indian Sports Heritage.

ERIC Educational Resources Information Center

Oxendine, Joseph B.

This book chronicles the story of sports among American Indians. Part 1 examines the nature and role of games in traditional Indian life, with five chapters on: Indian concepts of sport; ball games; foot racing; other sports; children's play; and games of chance. Part 2 looks at the emergence of Indians in modern sport, with five chapters on:…

Further blood genetic studies on Amazonian diversity--data from four Indian groups.

PubMed

Callegari-Jacques, S M; Salzano, F M; Weimer, T A; Hutz, M H; Black, F L; Santos, S E; Guerreiro, J F; Mestriner, M A; Pandey, J P

1994-01-01

Information related to 31 protein genetic systems was obtained for 307 individuals affiliated with the Cinta Larga, Karitiana, Surui and Kararaô Indians of northern Brazil. In terms of genetic distances the Cinta Larga showed more similarities with the Karitiana (both are Tupi-speaking tribes), while at a more distant level the Surui clustered with the Kararaô. The latter, a Cayapo subgroup, showed a completely different genetic constitution from the other subgroups of this same tribe. Both the Kararaô and Karitiana are small, remnant populations, and their gene pools have presumably been severely affected by random and founder effects. These results were incorporated with those of 25 other Amazonian Indian tribes, and analysis by two multivariate techniques confirmed a previously observed geographical dichotomy, suggesting either that the Amazon river constitutes a barrier to north-south gene flow or that latitudinally different past migrations entered the region from the west.

Characteristics of the fractional cloud cover and its altitude distribution over the Indian Ocean region derived from NOAA14-AVHRR

NASA Astrophysics Data System (ADS)

Suresh Raju, C.; Rajeev, K.; Parameswaran, K.

during this period is the minimum cloudiness observed around Srilanka during the Indian summer monsoon season, which is more discernable in high clouds. The cloud occurrence over the Indian subcontinent is less than 20% during the period of December to March. The presence of double inter tropical convergence zone (ITCZ), characterized by large cloud bands that are confined in latitude and elongated in longitude, are observed over Indian Ocean during November to March period, though the frequency of occurrence of such events is very small.

Interaction Between the Himalaya and the Flexed Indian Plate--Spatial Fluctuations in Seismic Hazard in India in the Past Millennium?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bilham, Roger; Szeliga, Walter

2008-07-08

Between the tenth and early 16th centuries three megaquakes allowed most of the northern edge of the Indian plate to slip 20-24 m northward relative to the overlying Himalaya. Although the renewal time for earthquakes with this large amount of slip is less than 1300 years given a geodetic convergence rate of 16-20 mm/yr, recently developed scaling laws for the Himalaya suggest that the past 200 years of great earthquakes may be associated with slip of less than 10 m and renewal times of approximately 500 years. These same theoretical models show that the rupture lengths of the Himalaya's Medievalmore » earthquakes (300-600 km) are too short to permit 24 m of slip given the relationships demonstrated by recent events. There is thus reason to suppose that recent earthquakes may have responded to different elastic driving forces from those that drove the megaquakes of Medieval times.An alternative source of energy to drive Himalayan earthquakes exists in the form of the elastic and gravitational energy stored in flexure of the Indian plate. The flexure is manifest in the form of a 200-450 m high bulge in central India, which is sustained by the forces of collision and by the end-loading of the plate by the Himalaya and southern Tibet. These flexural stresses are responsible for earthquakes in the sub-continent. The abrupt release of stress associated with the northward translation of the northern edge of the Indian plate by 24 m, were the process entirely elastic, would result in a deflation of the crest of the bulge by roughly 0.8 m. Geometrical changes, however, would be moderated by viscous rheologies in the plate and by viscous flow in the mantle in the following centuries.The hypothesized relaxation of flexural geometry following the Himalayan megaquake sequence would have the effect of backing-off stresses throughout central India resulting in quiescence both in the Himalaya and the Indian plate. The historical record shows an absence of great Himalayan

25 CFR 502.13 - Indian tribe.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Indian tribe. 502.13 Section 502.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.13 Indian tribe. Indian tribe means any Indian tribe, band, nation, or other organized group or...

25 CFR 502.13 - Indian tribe.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Indian tribe. 502.13 Section 502.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.13 Indian tribe. Indian tribe means any Indian tribe, band, nation, or other organized group or...

25 CFR 502.13 - Indian tribe.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Indian tribe. 502.13 Section 502.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.13 Indian tribe. Indian tribe means any Indian tribe, band, nation, or other organized group or...

25 CFR 502.13 - Indian tribe.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Indian tribe. 502.13 Section 502.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.13 Indian tribe. Indian tribe means any Indian tribe, band, nation, or other organized group or...

25 CFR 502.13 - Indian tribe.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Indian tribe. 502.13 Section 502.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.13 Indian tribe. Indian tribe means any Indian tribe, band, nation, or other organized group or...

77 FR 76514 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary--Policy and... the Indian Gaming Regulatory Act of 1988 (IGRA) Public Law 100-497, 25 U.S.C. 2701 et seq., the...

25 CFR 502.12 - Indian lands.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Indian lands. 502.12 Section 502.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.12 Indian lands. Indian lands means: (a) Land within the limits of an Indian reservation; or (b) Land...

25 CFR 502.12 - Indian lands.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Indian lands. 502.12 Section 502.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.12 Indian lands. Indian lands means: (a) Land within the limits of an Indian reservation; or (b) Land...

25 CFR 502.12 - Indian lands.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Indian lands. 502.12 Section 502.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.12 Indian lands. Indian lands means: (a) Land within the limits of an Indian reservation; or (b) Land...

25 CFR 502.12 - Indian lands.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Indian lands. 502.12 Section 502.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.12 Indian lands. Indian lands means: (a) Land within the limits of an Indian reservation; or (b) Land...

25 CFR 502.12 - Indian lands.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Indian lands. 502.12 Section 502.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.12 Indian lands. Indian lands means: (a) Land within the limits of an Indian reservation; or (b) Land...

Genetic affinities among the lower castes and tribal groups of India: inference from Y chromosome and mitochondrial DNA.

PubMed

Thanseem, Ismail; Thangaraj, Kumarasamy; Chaubey, Gyaneshwer; Singh, Vijay Kumar; Bhaskar, Lakkakula V K S; Reddy, B Mohan; Reddy, Alla G; Singh, Lalji

2006-08-07

India is a country with enormous social and cultural diversity due to its positioning on the crossroads of many historic and pre-historic human migrations. The hierarchical caste system in the Hindu society dominates the social structure of the Indian populations. The origin of the caste system in India is a matter of debate with many linguists and anthropologists suggesting that it began with the arrival of Indo-European speakers from Central Asia about 3500 years ago. Previous genetic studies based on Indian populations failed to achieve a consensus in this regard. We analysed the Y-chromosome and mitochondrial DNA of three tribal populations of southern India, compared the results with available data from the Indian subcontinent and tried to reconstruct the evolutionary history of Indian caste and tribal populations. No significant difference was observed in the mitochondrial DNA between Indian tribal and caste populations, except for the presence of a higher frequency of west Eurasian-specific haplogroups in the higher castes, mostly in the north western part of India. On the other hand, the study of the Indian Y lineages revealed distinct distribution patterns among caste and tribal populations. The paternal lineages of Indian lower castes showed significantly closer affinity to the tribal populations than to the upper castes. The frequencies of deep-rooted Y haplogroups such as M89, M52, and M95 were higher in the lower castes and tribes, compared to the upper castes. The present study suggests that the vast majority (> 98%) of the Indian maternal gene pool, consisting of Indio-European and Dravidian speakers, is genetically more or less uniform. Invasions after the late Pleistocene settlement might have been mostly male-mediated. However, Y-SNP data provides compelling genetic evidence for a tribal origin of the lower caste populations in the subcontinent. Lower caste groups might have originated with the hierarchical divisions that arose within the tribal

Genetic affinities among the lower castes and tribal groups of India: inference from Y chromosome and mitochondrial DNA

PubMed Central

Thanseem, Ismail; Thangaraj, Kumarasamy; Chaubey, Gyaneshwer; Singh, Vijay Kumar; Bhaskar, Lakkakula VKS; Reddy, B Mohan; Reddy, Alla G; Singh, Lalji

2006-01-01

Background India is a country with enormous social and cultural diversity due to its positioning on the crossroads of many historic and pre-historic human migrations. The hierarchical caste system in the Hindu society dominates the social structure of the Indian populations. The origin of the caste system in India is a matter of debate with many linguists and anthropologists suggesting that it began with the arrival of Indo-European speakers from Central Asia about 3500 years ago. Previous genetic studies based on Indian populations failed to achieve a consensus in this regard. We analysed the Y-chromosome and mitochondrial DNA of three tribal populations of southern India, compared the results with available data from the Indian subcontinent and tried to reconstruct the evolutionary history of Indian caste and tribal populations. Results No significant difference was observed in the mitochondrial DNA between Indian tribal and caste populations, except for the presence of a higher frequency of west Eurasian-specific haplogroups in the higher castes, mostly in the north western part of India. On the other hand, the study of the Indian Y lineages revealed distinct distribution patterns among caste and tribal populations. The paternal lineages of Indian lower castes showed significantly closer affinity to the tribal populations than to the upper castes. The frequencies of deep-rooted Y haplogroups such as M89, M52, and M95 were higher in the lower castes and tribes, compared to the upper castes. Conclusion The present study suggests that the vast majority (>98%) of the Indian maternal gene pool, consisting of Indio-European and Dravidian speakers, is genetically more or less uniform. Invasions after the late Pleistocene settlement might have been mostly male-mediated. However, Y-SNP data provides compelling genetic evidence for a tribal origin of the lower caste populations in the subcontinent. Lower caste groups might have originated with the hierarchical divisions

78 FR 17428 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-21

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs... CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary... section 11 of the Indian Gaming Regulatory Act of 1988 (IGRA), Public Law 100-497, 25 U.S.C. 2710 et seq...

Identification of novel target genes involved in Indian Fanconi anemia patients using microarray.

PubMed

Shyamsunder, Pavithra; Ganesh, Kripa S; Vidyasekar, Prasanna; Mohan, Sheila; Verma, Rama Shanker

2013-12-01

Fanconi anemia (FA) is a genetic disorder characterized by progressive bone marrow failure and a predisposition to cancers. Mutations have been documented in 15 FA genes that participate in the FA-BRCA DNA repair pathway, a fundamental pathway in the development of the disease and the presentation of its characteristic symptoms. Certain symptoms such as oxygen sensitivity, hematological abnormalities and impaired immunity suggest that FA proteins could participate in or independently control other pathways as well. In this study, we identified 9 DNA repair genes that were down regulated in a genome wide analysis of 6 Indian Fanconi anemia patients. Functional clustering of a total of 233 dysregulated genes identified key biological processes that included regulation of transcription, DNA repair, cell cycle and chromosomal organization. Microarray data revealed the down regulation of ATXN3, ARID4A and ETS-1, which were validated by RTPCR in a subsequent sample set of 9 Indian FA patients. Here we report for the first time a gene expression profile of Fanconi anemia patients from the Indian population and a pool of genes that might aid in the acquisition and progression of the FA phenotype. © 2013 Elsevier B.V. All rights reserved.

The Top 10 Ethical Challenges in Dental Practice in Indian Scenario: Dentist Perspective

PubMed Central

Kemparaj, Vanishree M.; Panchmal, Ganesh Shenoy; Kadalur, Umashankar Gangadaraiah

2018-01-01

Aim: This exploratory qualitative research is an attempt to assess the health care ethical challenges in dental practice in an Indian scenario. Methodology: Qualitative indepth interview was conducted on 20 dental professionals to assess the ethical challenges prevailing in dental practice in Indian scenario. After obtaining the responses the verbatims were categorized into categories and finally 36 themes emerged. Later from two group of 6 panellists each after conducting focus group discussion the themes of ethical issues occurring in dental practice were ranked based on order of significance impact on the practice, patient and society using Delphi method. Result: The top ten ethical challenges listed by the panellists are inadequate sterilization and waste management in dental clinics, poor knowledge and attitude towards ethics among our dental practitioners, in competence among dental professional, increase in cost of oral health service, poor informed consent process, requirement of consensus about the treatment procedures among dentists, Conflict in Advertising, clustering of dental clinics in urban areas, disagreement with treatment modalities among dentist and patient, poor medical record maintenance among our dental practitioners. Conclusion: The study attempts to bring the prevailing ethical challenges in oral health care practice in Indian scenario. PMID:29599593

Phenotypic and genetic characterization of Dunaliella (Chlorophyta) from Indian salinas and their diversity

PubMed Central

2012-01-01

Background The genus Dunaliella (Class – Chlorophyceae) is widely studied for its tolerance to extreme habitat conditions, physiological aspects and many biotechnological applications, such as a source of carotenoids and many other bioactive compounds. Biochemical and molecular characterization is very much essential to fully explore the properties and possibilities of the new isolates of Dunaliella. In India, hyper saline lakes and salt pans were reported to bloom with Dunaliella spp. However, except for the economically important D. salina, other species are rarely characterized taxonomically from India. Present study was conducted to describe Dunaliella strains from Indian salinas using a combined morphological, physiological and molecular approach with an aim to have a better understanding on the taxonomy and diversity of this genus from India. Results Comparative phenotypic and genetic studies revealed high level of diversity within the Indian Dunaliella isolates. Species level identification using morphological characteristics clearly delineated two strains of D. salina with considerable β-carotene content (>20 pg/cell). The variation in 18S rRNA gene size, amplified with MA1-MA2 primers, ranged between ~1800 and ~2650 base pairs, and together with the phylogeny based on ITS gene sequence provided a pattern, forming five different groups within Indian Dunaliella isolates. Superficial congruency was observed between ITS and rbcL gene phylogenetic trees with consistent formation of major clades separating Indian isolates into two distinct clusters, one with D. salina and allied strains, and another one with D. viridis and allied strains. Further in both the trees, few isolates showed high level of genetic divergence than reported previously for Dunaliella spp. This indicates the scope of more numbers of clearly defined/unidentified species/sub-species within Indian Dunaliella isolates. Conclusion Present work illustrates Indian Dunaliella strains

Current Scenario of Prevalence of Vitamin D Deficiency in Ostensibly Healthy Indian Population: A Hospital Based Retrospective Study.

PubMed

Shukla, Kirtikar; Sharma, Shikha; Gupta, Aditi; Raizada, Arun; Vinayak, Kamini

2016-10-01

25-hydroxy vitamin D [25(OH) vit D] deficiency is a serious public health problem, particularly in the Indian sub-continent. The objective of the present study was to study the prevalence of 25(OH) vit D in different age groups. The data of 25(OH) vit D assay of 26,346 ostensibly healthy individuals, enrolled under executive health checkup at Medanta The Medicity, Gurgaon, over a period of 3 years, were extracted from the hospital information system and reviewed extensively. 25(OH) vit D deficiency (VDD) was defined as 25(OH) vit D < 20 ng/ml, insufficiency (VDI) as 25(OH) vit D between 20 and 40 ng/ml and 25(OH) vit D sufficiency (VDS) as 25(OH) D > 40 ng/mL. 25(OH) vit D deficiency (VDD + VDI) was observed in 93 % of the subject population. Maximum number of the subjects belonged to the age group of 41-60 years. 59 % had frank 25(OH) vit D deficiency when cut off level was <20 ng/mL. Mean value of 25(OH) vit D in our subjects was 21.4 ± 14.4 ng/mL. Significant difference in 25(OH) vit D level was observed in between male and female subjects. Simultaneously 25(OH) vit D levels were significantly lower in the patient visited hospital in winter-spring season than the summer-autumn season (p > 0.001). Our study demonstrates a high prevalence of 25(OH) vit D deficiency in an ostensibly healthy Indian population. There is a need for redefining our reference ranges according to our population and extensively improving the status of vitamin D.

American Indian Music for the Classroom: An Indian Education Curriculum Unit.

ERIC Educational Resources Information Center

Stutzman, Esther

This teaching guide, produced in cooperation with Indian parents, students and teachers, offers classroom material on the complex culture and history of American Indians. The guide suggests youngsters be taught that, contrary to stereotypes, there was a wide variation of Indian tribal groups and cultures in North America. A list of 14…

Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons.

PubMed

Kariyawasam, Udeshika Lakmini; Selvapandiyan, Angamuthu; Rai, Keshav; Wani, Tasaduq Hussain; Ahuja, Kavita; Beg, Mizra Adil; Premathilake, Hasitha Upendra; Bhattarai, Narayan Raj; Siriwardena, Yamuna Deepani; Zhong, Daibin; Zhou, Guofa; Rijal, Suman; Nakhasi, Hira; Karunaweera, Nadira D

2017-12-22

Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sri Lankan L. donovani differs from other L. donovani strains, both at the molecular and biochemical level. To investigate the different species or strain-specific differences of L. donovani in Sri Lanka we evaluated sequence variation of the kinetoplastid DNA (kDNA). Parasites isolated from skin lesions of 34 CL patients and bone marrow aspirates from 4 VL patients were genotyped using the kDNA minicircle PCR analysis. A total of 301 minicircle sequences that included sequences from Sri Lanka, India, Nepal and six reference species of Leishmania were analyzed. Haplotype diversity of Sri Lankan isolates were high (H d  = 0.757) with strong inter-geographical genetic differentiation (F ST  > 0.25). In this study, L. donovani isolates clustered according to their geographic origin, while Sri Lankan isolates formed a separate cluster and were clearly distinct from other Leishmania species. Within the Sri Lankan group, there were three distinct sub-clusters formed, from CL patients who responded to standard antimony therapy, CL patients who responded poorly to antimony therapy and from VL patients. There was no specific clustering of sequences based on geographical origin within Sri Lanka. This study reveals high levels of haplotype diversity of L. donovani in Sri Lanka with a distinct genetic association with clinically relevant phenotypic characteristics. The use of genetic tools to identify clinically relevant features of Leishmania parasites has important therapeutic implications for leishmaniasis.

Recent TB transmission, clustering and predictors of large clusters in London, 2010–2012: results from first 3 years of universal MIRU-VNTR strain typing

PubMed Central

Hamblion, Esther L; Le Menach, Arnaud; Anderson, Laura F; Lalor, Maeve K; Brown, Tim; Abubakar, Ibrahim; Anderson, Charlotte; Maguire, Helen; Anderson, Sarah R

2016-01-01

Background The incidence of TB has doubled in the last 20 years in London. A better understanding of risk groups for recent transmission is required to effectively target interventions. We investigated the molecular epidemiological characteristics of TB cases to estimate the proportion of cases due to recent transmission, and identify predictors for belonging to a cluster. Methods The study population included all culture-positive TB cases in London residents, notified between January 2010 and December 2012, strain typed using 24-loci multiple interspersed repetitive units-variable number tandem repeats. Multivariable logistic regression analysis was performed to assess the risk factors for clustering using sociodemographic and clinical characteristics of cases and for cluster size based on the characteristics of the first two cases. Results There were 10 147 cases of which 5728 (57%) were culture confirmed and 4790 isolates (84%) were typed. 2194 (46%) were clustered in 570 clusters, and the estimated proportion attributable to recent transmission was 34%. Clustered cases were more likely to be UK born, have pulmonary TB, a previous diagnosis, a history of substance abuse or alcohol abuse and imprisonment, be of white, Indian, black-African or Caribbean ethnicity. The time between notification of the first two cases was more likely to be <90 days in large clusters. Conclusions Up to a third of TB cases in London may be due to recent transmission. Resources should be directed to the timely investigation of clusters involving cases with risk factors, particularly those with a short period between the first two cases, to interrupt onward transmission of TB. PMID:27417280

Indians Giving: The New Philanthropy in Indian Country.

ERIC Educational Resources Information Center

Ambler, Marjane

1994-01-01

Describes five model philanthropic programs that provide funding to Native American causes. Indicates that Native Americans are creating their own foundations and working as partners with non-Indian philanthropies. Discusses the Seventh Generation Fund, American Indian College Fund, Eagle Staff Fund Collaborative, Montana Community Foundation, and…

34 CFR 300.21 - Indian and Indian tribe.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Indian and Indian tribe. 300.21 Section 300.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF...

Observed correlations between aerosol and cloud properties in an Indian Ocean trade cumulus regime

NASA Astrophysics Data System (ADS)

Pistone, K.; Praveen, P. S.; Thomas, R. M.; Ramanathan, V.; Wilcox, E.; Bender, F. A.-M.

2015-10-01

There are many contributing factors which determine the micro- and macrophysical properties of clouds, including atmospheric structure, dominant meteorological conditions, and aerosol concentration, all of which may be coupled to one another. In the quest to determine aerosol effects on clouds, these potential relationships must be understood, as changes in atmospheric conditions due to aerosol may change the expected magnitude of indirect effects by altering cloud properties in unexpected ways. Here we describe several observed correlations between aerosol conditions and cloud and atmospheric properties in the Indian Ocean winter monsoon season. In the CARDEX (Cloud, Aerosol, Radiative forcing, Dynamics EXperiment) field campaign conducted in February and March 2012 in the northern Indian Ocean, continuous measurements of atmospheric precipitable water vapor and the liquid water path (LWP) of trade cumulus clouds were made, concurrent with measurements of water vapor flux, cloud and aerosol vertical profiles, meteorological data, and surface and total-column aerosol. Here we present evidence of a positive correlation between aerosol and cloud LWP which becomes clear after the data are filtered to control for the natural meteorological variability in the region. We then use the aircraft and ground observatory measurements to explore the mechanisms behind the observed aerosol-LWP correlation. We determine that increased boundary-layer humidity lowering the cloud base is responsible for the observed increase in cloud liquid water. Large-scale analysis indicates that high pollution cases originate with a highly-polluted boundary layer air mass approaching the observatory from a northwesterly direction. This polluted mass exhibits higher temperatures and humidity than the clean case, the former of which may be attributable to heating due to aerosol absorption of solar radiation over the subcontinent. While high temperature conditions dispersed along with the high

Neem oil poisoning: Case report of an adult with toxic encephalopathy

PubMed Central

Mishra, Ajay; Dave, Nikhil

2013-01-01

Neem oil has widespread use in Indian subcontinent due to its many bioactive properties. Azadirachtin, an active ingredient, is implicated in causing the effects seen in neem oil poisoning. Neem oil poisoning is rare in adults. This report highlights the toxicity associated with neem oil poisoning in an elderly male. The patient presented with vomiting, seizures, metabolic acidosis, and toxic encephalopathy. The patient recovered completely with symptomatic treatment. PMID:24339648

Neem oil poisoning: Case report of an adult with toxic encephalopathy.

PubMed

Mishra, Ajay; Dave, Nikhil

2013-09-01

Neem oil has widespread use in Indian subcontinent due to its many bioactive properties. Azadirachtin, an active ingredient, is implicated in causing the effects seen in neem oil poisoning. Neem oil poisoning is rare in adults. This report highlights the toxicity associated with neem oil poisoning in an elderly male. The patient presented with vomiting, seizures, metabolic acidosis, and toxic encephalopathy. The patient recovered completely with symptomatic treatment.

Environmental Assessment for the Proposed Construction of a H-70 Fuel Storage Facility and a Medical Pharmacy

DTIC Science & Technology

2003-05-01

Southeast Asia, or the Indian subcontinent including, for example, Cambodia, China, India, Japan, Korea, Malaysia , Pakistan, or the Philippine Islands; and... OSHA ). The State of Colorado also has regulations pertaining to ACM abatement. Emissions of asbestos fibers into the ambient air are regulated in...contours. Construction noise is planned to occur for periods of 8 hours a day, Monday through Saturday. According to the OSHA , it is unacceptable for

American Indian Stereotypes: The Truth Behind the Hype. An Indian Education Curriculum Unit.

ERIC Educational Resources Information Center

Stutzman, Esther

This curriculum guide dispels the stereotypes of American Indians that humiliate and degrade real Indian culture and add fuel to the fire of racism and prejudice. It begins with a timeline of American Indian history from 15,000 B.C. to the present, and compares it to a historical timeline of Europe-Asia. The stereotype of the savage Indian is…

48 CFR 52.226-1 - Utilization of Indian Organizations and Indian-Owned Economic Enterprises.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Organizations and Indian-Owned Economic Enterprises. 52.226-1 Section 52.226-1 Federal Acquisition Regulations... Economic Enterprises. As prescribed in 26.104, insert the following clause: Utilization of Indian Organizations and Indian-Owned Economic Enterprises (JUN 2000) (a) Definitions. As used in this clause: Indian...

77 FR 43110 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-23

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs...: Effective Date: July 23, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian..., (202) 219-4066. [[Page 43111

Hereditary polymorphic light eruption of American Indians: occurrence in non-Indians with polymorphic light eruption.

PubMed

Fusaro, R M; Johnson, J A

1996-04-01

Hereditary polymorphic light eruption (HPLE) occurs unique ly in the American Indian and Inuit and exhibits autosomal dominant transmission. Because the cutaneous expression of HPLE resembles that of polymorphic light eruption (PLE) and because many non-Indians in the United States have American Indian heritage, some instances of PLE may actually be HPLE. Our purpose was to determine whether non-Indian patients with PLE have characteristics suggestive of HPLE. We surveyed in Nebraska 25 European-Caucasian and 36 African-American patients with PLE for American Indian heritage and photosensitive relatives. Nonphotosensitive subjects (52 Caucasians and 40 African Americans) were surveyed for American Indian heritage. American Indian heritage occurred in 11 Caucasian patients (44%); of those, seven (64%) had photosensitive relatives. Likewise, 29 African Americans (81%) had American Indian heritage; 19 (66%) of those had photosensitive relatives. American Indian heritage occurred in 10 Caucasian control subjects (19%) and in 34 African-American control subjects (85%). If American Indian heritage and a family history of photosensitivity are definitive for HPLE, seven (28%) of our Caucasian patients and 19 (53%) of our African-American patients have HPLE rather than PLE. We urge physicians who suspect PLE in non-Indians to ask about American Indian heritage and photosensitive relatives and to screen their present patients with PLE for such characteristics.

Multivariate Statistical Analysis of Water Quality data in Indian River Lagoon, Florida

NASA Astrophysics Data System (ADS)

Sayemuzzaman, M.; Ye, M.

2015-12-01

The Indian River Lagoon, is part of the longest barrier island complex in the United States, is a region of particular concern to the environmental scientist because of the rapid rate of human development throughout the region and the geographical position in between the colder temperate zone and warmer sub-tropical zone. Thus, the surface water quality analysis in this region always brings the newer information. In this present study, multivariate statistical procedures were applied to analyze the spatial and temporal water quality in the Indian River Lagoon over the period 1998-2013. Twelve parameters have been analyzed on twelve key water monitoring stations in and beside the lagoon on monthly datasets (total of 27,648 observations). The dataset was treated using cluster analysis (CA), principle component analysis (PCA) and non-parametric trend analysis. The CA was used to cluster twelve monitoring stations into four groups, with stations on the similar surrounding characteristics being in the same group. The PCA was then applied to the similar groups to find the important water quality parameters. The principal components (PCs), PC1 to PC5 was considered based on the explained cumulative variances 75% to 85% in each cluster groups. Nutrient species (phosphorus and nitrogen), salinity, specific conductivity and erosion factors (TSS, Turbidity) were major variables involved in the construction of the PCs. Statistical significant positive or negative trends and the abrupt trend shift were detected applying Mann-Kendall trend test and Sequential Mann-Kendall (SQMK), for each individual stations for the important water quality parameters. Land use land cover change pattern, local anthropogenic activities and extreme climate such as drought might be associated with these trends. This study presents the multivariate statistical assessment in order to get better information about the quality of surface water. Thus, effective pollution control/management of the surface

Multi-temporal clustering of continental floods and associated atmospheric circulations

NASA Astrophysics Data System (ADS)

Liu, Jianyu; Zhang, Yongqiang

2017-12-01

Investigating clustering of floods has important social, economic and ecological implications. This study examines the clustering of Australian floods at different temporal scales and its possible physical mechanisms. Flood series with different severities are obtained by peaks-over-threshold (POT) sampling in four flood thresholds. At intra-annual scale, Cox regression and monthly frequency methods are used to examine whether and when the flood clustering exists, respectively. At inter-annual scale, dispersion indices with four-time variation windows are applied to investigate the inter-annual flood clustering and its variation. Furthermore, the Kernel occurrence rate estimate and bootstrap resampling methods are used to identify flood-rich/flood-poor periods. Finally, seasonal variation of horizontal wind at 850 hPa and vertical wind velocity at 500 hPa are used to investigate the possible mechanisms causing the temporal flood clustering. Our results show that: (1) flood occurrences exhibit clustering at intra-annual scale, which are regulated by climate indices representing the impacts of the Pacific and Indian Oceans; (2) the flood-rich months occur from January to March over northern Australia, and from July to September over southwestern and southeastern Australia; (3) stronger inter-annual clustering takes place across southern Australia than northern Australia; and (4) Australian floods are characterised by regional flood-rich and flood-poor periods, with 1987-1992 identified as the flood-rich period across southern Australia, but the flood-poor period across northern Australia, and 2001-2006 being the flood-poor period across most regions of Australia. The intra-annual and inter-annual clustering and temporal variation of flood occurrences are in accordance with the variation of atmospheric circulation. These results provide relevant information for flood management under the influence of climate variability, and, therefore, are helpful for developing

A study on phenomenology of Dhat syndrome in men in a general medical setting.

PubMed

Prakash, Sathya; Sharan, Pratap; Sood, Mamta

2016-01-01

"Dhat syndrome" is believed to be a culture-bound syndrome of the Indian subcontinent. Although many studies have been performed, many have methodological limitations and there is a lack of agreement in many areas. The aim is to study the phenomenology of "Dhat syndrome" in men and to explore the possibility of subtypes within this entity. It is a cross-sectional descriptive study conducted at a sex and marriage counseling clinic of a tertiary care teaching hospital in Northern India. An operational definition and assessment instrument for "Dhat syndrome" was developed after taking all concerned stakeholders into account and review of literature. It was applied on 100 patients along with socio-demographic profile, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Mini International Neuropsychiatric Interview, and Postgraduate Institute Neuroticism Scale. For statistical analysis, descriptive statistics, group comparisons, and Pearson's product moment correlations were carried out. Factor analysis and cluster analysis were done to determine the factor structure and subtypes of "Dhat syndrome." A diagnostic and assessment instrument for "Dhat syndrome" has been developed and the phenomenology in 100 patients has been described. Both the health beliefs scale and associated symptoms scale demonstrated a three-factor structure. The patients with "Dhat syndrome" could be categorized into three clusters based on severity. There appears to be a significant agreement among various stakeholders on the phenomenology of "Dhat syndrome" although some differences exist. "Dhat syndrome" could be subtyped into three clusters based on severity.

25 CFR 273.45 - Indian preference.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Indian preference. 273.45 Section 273.45 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT General Contract Requirements § 273.45 Indian...

25 CFR 273.45 - Indian preference.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Indian preference. 273.45 Section 273.45 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT General Contract Requirements § 273.45 Indian...

25 CFR 273.45 - Indian preference.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Indian preference. 273.45 Section 273.45 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT General Contract Requirements § 273.45 Indian...

25 CFR 273.45 - Indian preference.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Indian preference. 273.45 Section 273.45 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT General Contract Requirements § 273.45 Indian...

48 CFR 52.226-1 - Utilization of Indian Organizations and Indian-Owned Economic Enterprises.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Utilization of Indian Organizations and Indian-Owned Economic Enterprises. 52.226-1 Section 52.226-1 Federal Acquisition Regulations... CLAUSES Text of Provisions and Clauses 52.226-1 Utilization of Indian Organizations and Indian-Owned...

48 CFR 52.226-1 - Utilization of Indian Organizations and Indian-Owned Economic Enterprises.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Utilization of Indian Organizations and Indian-Owned Economic Enterprises. 52.226-1 Section 52.226-1 Federal Acquisition Regulations... CLAUSES Text of Provisions and Clauses 52.226-1 Utilization of Indian Organizations and Indian-Owned...

48 CFR 52.226-1 - Utilization of Indian Organizations and Indian-Owned Economic Enterprises.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Utilization of Indian Organizations and Indian-Owned Economic Enterprises. 52.226-1 Section 52.226-1 Federal Acquisition Regulations... CLAUSES Text of Provisions and Clauses 52.226-1 Utilization of Indian Organizations and Indian-Owned...

48 CFR 52.226-1 - Utilization of Indian Organizations and Indian-Owned Economic Enterprises.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Utilization of Indian Organizations and Indian-Owned Economic Enterprises. 52.226-1 Section 52.226-1 Federal Acquisition Regulations... CLAUSES Text of Provisions and Clauses 52.226-1 Utilization of Indian Organizations and Indian-Owned...

Characterization of hydrometeors and precipitation over the Indian monsoon region using aircraft measurements

NASA Astrophysics Data System (ADS)

Maheskumar, R. S.; Padmakumari, B.; Konwar, Mahen; Morwal, S. B.; Deshpande, C. G.

2018-06-01

In-situ observations of cloud microphysical properties, carried out over different parts of Indian sub-continent using an instrumented research aircraft during Phase-I of Cloud Aerosol Interaction and Precipitation Enhancement EXperiment (CAIPEEX) from June to September 2009, were studied. Different cloud probes were used to characterize the hydrometeor and precipitation types in the monsoon clouds. The results revealed that all liquid phase hydrometeors were present at temperatures -12 °C to 15 °C. Most of the presence of rain drops were found in the liquid water content (LWC) range from 0.5 to 2 g/m3. In general, rain drops are initiated when the droplet effective radius (Re) exceeded 12 μm. Rain dominated at the tops of young growing convective clouds even at temperatures colder than -10 °C. Mixed phase hydrometeors were present at temperatures from -2 °C to -18 °C. The cases where mixed phase precipitation occurred at temperatures warmer than about -7 °C were associated with influx of transported dust aerosol at the upper (supercooled) region of these cloud systems. Ice only hydrometeors were found at temperatures extending from -10 °C to -22 °C. Most of the monsoon rain is produced by warm and cold cloud/mixed-phase processes in the cloud. The combined Re from two different cloud probes is useful for validation of satellite derived cloud microphysical parameter.

The American Indian: A Natural Philosopher

ERIC Educational Resources Information Center

Bunge, Robert P.

1978-01-01

Describes American Indian philosophy, Indian attitudes on man's place in the cosmos, Indian socio-political practice, Indian moral values and community philosophy, and the differences between "white" and Indian culture. (RK)

25 CFR 273.45 - Indian preference.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Indian preference. 273.45 Section 273.45 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT General Contract Requirements § 273.45 Indian preference. (a...

American Indian Men's Perceptions of Breast Cancer Screening for American Indian Women.

PubMed

Filippi, Melissa K; Pacheco, Joseph; James, Aimee S; Brown, Travis; Ndikum-Moffor, Florence; Choi, Won S; Greiner, K Allen; Daley, Christine M

2014-01-01

Screening, especially screening mammography, is vital for decreasing breast cancer incidence and mortality. Screening rates in American Indian women are low compared to other racial/ethnic groups. In addition, American Indian women are diagnosed at more advanced stages and have lower 5-year survival rate than others. To better address the screening rates of American Indian women, focus groups (N=8) were conducted with American Indian men (N=42) to explore their perceptions of breast cancer screening for American Indian women. Our intent was to understand men's support level toward screening. Using a community-based participatory approach, focus groups were audio-taped, transcribed verbatim, and analyzed using a text analysis approach developed by our team. Topics discussed included breast cancer and screening knowledge, barriers to screening, and suggestions to improve screening rates. These findings can guide strategies to improve knowledge and awareness, communication among families and health care providers, and screening rates in American Indian communities.

Overweight, obesity and related non-communicable diseases in Asian Indian girls and women.

PubMed

Chopra, S M; Misra, A; Gulati, S; Gupta, R

2013-07-01

The prevalence of obesity is rising globally and in India. Overweight, obesity and related diseases need to be delineated in Asian Indian women. A literature search was done using key words like 'obesity', 'Asian Indian women', 'body fat distribution', 'type 2 diabetes', 'fertility', 'polycystic ovarian disease', metabolic syndrome', 'cardiovascular disease', 'non-alcoholic fatty liver disease', 'gender', 'sex' and 'prevalence' up to September 2012 in Pubmed and Google Scholar search engines. This review highlights the Asian Indian body composition with regards to obesity and provides a collated perspective of gender-specific prevalence of the co-morbidities. Recent data show that women (range of prevalence of overweight and obesity from different studies 15-61%) have higher prevalence of overweight and obesity as compared with men (range of prevalence of overweight and obesity from different studies 12-54%) in India and that obesity is increasing in the youth. The prevalence of overweight and obesity in both men and women steeply rose in a Punjabi community from Jaipur. Importantly, prevalence of abdominal obesity has been consistently higher in women than in men. The lowest prevalence (6.0%) of type 2 diabetes mellitus in women is reported from South India (rural Andhra Pradesh; 2006) and the highest (14.0%) by the National Urban Diabetes Survey (2001). Although the clustering of cardiovascular disease risk factors was generally high, it increased further in post-menopausal women. There are a number of factors that predispose Indian women to obesity; sedentary behaviour, imbalanced diets, sequential and additive postpartum weight gain and further decrease in physical activity during this period and cultural issues. In view of these data, preventive measures should be specifically targeted to Indian women.

Observational Evidence of Impacts of Aerosols on Seasonal-to-Interannual Variability of the Asian Monsoon

NASA Technical Reports Server (NTRS)

Lau, K.-M.; Kim, K.-M.; Hsu, N. C.

2006-01-01

Observational evidences are presented showing that the Indian subcontinent and surrounding regions are subject to heavy loading of absorbing aerosols (dust and black carbon), with strong seasonality closely linked to the monsoon annual rainfall cycle. Increased loading of absorbing aerosols over the Indo-Gangetic Plain in April-May is associated with a) increased heating of the upper troposphere over the Tibetan Plateau, b) an advance of the monsoon rainy season, and c) subsequent enhancement of monsoon rainfall over the South Asia subcontinent, and reduction over East Asia. Also presented are radiative transfer calculations showing how differential solar absorption by aerosols over bright surface (desert or snow cover land) compared to dark surface (vegetated land and ocean), may be instrumental in triggering an aerosol-monsoon large-scale circulation and water cycle feedback, consistent with the elevated heat pump hypothesis (Lau et al. 2006).

77 FR 59641 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-28

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Deemed Approved Amended Tribal-State Class III Gaming Compact. SUMMARY: This.... FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...

2 CFR 25.335 - Indian Tribe (or “Federally recognized Indian Tribe”).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Indian Tribe (or âFederally recognized Indian Tribeâ). 25.335 Section 25.335 Grants and Agreements Office of Management and Budget Guidance for... Reserved UNIVERSAL IDENTIFIER AND CENTRAL CONTRACTOR REGISTRATION Definitions § 25.335 Indian Tribe (or...

78 FR 54908 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of approved Tribal-State Class III Gaming Compact... INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant...

78 FR 26801 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-08

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Approved Tribal-State Class III Gaming Compact... between the Menominee Indian Tribe of Wisconsin and the State of Wisconsin (Amendment). DATES: Effective...

Indian Family Exception Doctrine: still losing children despite the Indian Child Welfare Act.

PubMed

Cross, Suzanne L

2006-01-01

Since 1982, the Indian Family Exception Doctrine has been circumventing the Indian Child Welfare Act of 1978. Although not clearly defined, the doctrine has been pivotal in several American Indian child welfare cases in the United States. Over time, the doctrine continues to evolve and self-define. Several phrases have become part of the definition, such as Indian family and culture. This doctrine presents major concerns and implications in the field of child welfare.

78 FR 62649 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Tribal-State Class III Gaming Compact taking effect... Indians and the State of California taking effect. DATES: Effective Date: October 22, 2013. FOR FURTHER...

78 FR 62650 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of extension of Tribal-State Class III Gaming Compact... CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary...

78 FR 62649 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Approved Tribal-State Class III Gaming Compact...: Effective Date: October 22, 2013. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian...

78 FR 54670 - Indian Gaming

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B711.IA000813] Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of extension of Tribal--State Class III Gaming Compact... CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the Deputy Assistant Secretary...

Resources for American Indian Rehabilitation.

ERIC Educational Resources Information Center

Thomason, Timothy C., Ed.

This directory is intended to provide a comprehensive listing of organizational and informational resources related to the rehabilitation needs of American Indians with disabilities. The guide is divided into two sections. The first section contains lists of American Indian organizations, American Indian centers, Bureau of Indian Affairs offices,…

Intra-cluster Globular Clusters in a Simulated Galaxy Cluster

NASA Astrophysics Data System (ADS)

Ramos-Almendares, Felipe; Abadi, Mario; Muriel, Hernán; Coenda, Valeria

2018-01-01

Using a cosmological dark matter simulation of a galaxy-cluster halo, we follow the temporal evolution of its globular cluster population. To mimic the red and blue globular cluster populations, we select at high redshift (z∼ 1) two sets of particles from individual galactic halos constrained by the fact that, at redshift z = 0, they have density profiles similar to observed ones. At redshift z = 0, approximately 60% of our selected globular clusters were removed from their original halos building up the intra-cluster globular cluster population, while the remaining 40% are still gravitationally bound to their original galactic halos. As the blue population is more extended than the red one, the intra-cluster globular cluster population is dominated by blue globular clusters, with a relative fraction that grows from 60% at redshift z = 0 up to 83% for redshift z∼ 2. In agreement with observational results for the Virgo galaxy cluster, the blue intra-cluster globular cluster population is more spatially extended than the red one, pointing to a tidally disrupted origin.

Indian Tribes as Developing Nations; A Question of Power: Indian Control of Indian Resource Development.

ERIC Educational Resources Information Center

Americans for Indian Opportunity, Inc., Albuquerque, NM.

The report discusses how Indian tribes can conserve and develop their own resources at their own pace and explores the options available to them as owners of valuable natural resources. Discussed are problems encountered by tribal leaders with various government agencies; the basic precepts of the Bureau of Indian Affairs; how the problems of…

The Indian Languages

ERIC Educational Resources Information Center

Strong, Augusta

1969-01-01

Appraisal of Boas'"Introduction to Handbook of American Indian Languages (1911), and Powell's "Indian Linguistic Famlies of America North of Mexico (1891), as reissued by University of Nebraska, Lincoln. (AF)

Kautilya’s Arthashastra: A Timeless Grand Strategy

DTIC Science & Technology

2011-06-01

life, Alexander was forced to retreat, by the rebellion of his army in the Indian subcontinent, and the glorious expansion of the Greek empire reached...cooked food , and beverages should be stationed at the rear. Various battle arrays and formations are enumerated for the conduct of the battle, and...the state, as both seek to achieve legitimacy in their eyes. The French counter insurgency theorist, David Galula states flatly that an insurgency is

Makran Mountain Range, Iran and Pakistan

NASA Technical Reports Server (NTRS)

1983-01-01

The long folded mountain ridges and valleys of the coastal Makran Ranges of Iran and Pakistan (26.0N, 63.0E) illustrate the classical Trellis type of drainage pattern, common in this region. The Dasht River and its tributaries is the principal drainage network for this area. To the left, the continental drift of the northward bound Indian sub-continent has caused the east/west parallel ranges to bend in a great northward arc.

1975 Annual Typhoon Report

DTIC Science & Technology

1995-01-01

southwest monsoon. Tropical Cyclone 24-75 formed just off the southwest tip of the Indian subcontinent. 3X tracked northwest and dissipated over water ...Tropical Cyclone 33-75 formed in late November and described an erratic track in the southwest portion of the Bay. The storm dissipated over water ...Leyte leaving 15 dead rains were spawned over the caused widespread flooding Choppy waters near capsized a crowded motorboat and 30 missing. FIGURE 4

Indian Legends.

ERIC Educational Resources Information Center

Gurnoe, Katherine J.; Skjervold, Christian, Ed.

Presenting American Indian legends, this material provides insight into the cultural background of the Dakota, Ojibwa, and Winnebago people. Written in a straightforward manner, each of the eight legends is associated with an Indian group. The legends included here are titled as follows: Minnesota is Minabozho's Land (Ojibwa); How We Got the…

Information About Indians of Iowa.

ERIC Educational Resources Information Center

Toothman, Maryann; Jensen, Denise

An intermediate or junior high level unit on Indians indigenous to Iowa focuses on history, culture, and cultural conflict between the Indians and white Americans. Many of the materials can be adapted for use in other states or for a more general unit on American Indians. Twenty lessons cover the location of Iowa; prehistoric Iowa; Indian society…

Genomic view on the peopling of India

PubMed Central

2012-01-01

India is known for its vast human diversity, consisting of more than four and a half thousand anthropologically well-defined populations. Each population differs in terms of language, culture, physical features and, most importantly, genetic architecture. The size of populations varies from a few hundred to millions. Based on the social structure, Indians are classified into various caste, tribe and religious groups. These social classifications are very rigid and have remained undisturbed by emerging urbanisation and cultural changes. The variable social customs, strict endogamy marriage practices, long-term isolation and evolutionary forces have added immensely to the diversification of the Indian populations. These factors have also led to these populations acquiring a set of Indian-specific genetic variations responsible for various diseases in India. Interestingly, most of these variations are absent outside the Indian subcontinent. Thus, this review is focused on the peopling of India, the caste system, marriage practice and the resulting health and forensic implications. PMID:23020857

Genomic view on the peopling of India.

PubMed

Tamang, Rakesh; Thangaraj, Kumarasamy

2012-10-01

India is known for its vast human diversity, consisting of more than four and a half thousand anthropologically well-defined populations. Each population differs in terms of language, culture, physical features and, most importantly, genetic architecture. The size of populations varies from a few hundred to millions. Based on the social structure, Indians are classified into various caste, tribe and religious groups. These social classifications are very rigid and have remained undisturbed by emerging urbanisation and cultural changes. The variable social customs, strict endogamy marriage practices, long-term isolation and evolutionary forces have added immensely to the diversification of the Indian populations. These factors have also led to these populations acquiring a set of Indian-specific genetic variations responsible for various diseases in India. Interestingly, most of these variations are absent outside the Indian subcontinent. Thus, this review is focused on the peopling of India, the caste system, marriage practice and the resulting health and forensic implications.

78 FR 42788 - American Indians Into Nursing; Notice of Competitive Grant Applications for American Indians Into...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service American Indians Into Nursing; Notice of Competitive Grant Applications for American Indians Into Nursing Program Announcement Type... the American Indians into Nursing Program (Section 112). This program is authorized under Section 112...

Beta-globin gene cluster haplotypes of Amerindian populations from the Brazilian Amazon region.

PubMed

Guerreiro, J F; Figueiredo, M S; Zago, M A

1994-01-01

We have determined the beta-globin cluster haplotypes for 80 Indians from four Brazilian Amazon tribes: Kayapó, Wayampí, Wayana-Apalaí, and Arára. The results are analyzed together with 20 Yanomámi previously studied. From 2 to 4 different haplotypes were identified for each tribe, and 7 of the possible 32 haplotypes were found in a sample of 172 chromosomes for which the beta haplotypes were directly determined or derived from family studies. The haplotype distribution does not differ significantly among the five populations. The two most common haplotypes in all tribes were haplotypes 2 and 6, with average frequencies of 0.843 and 0.122, respectively. The genetic affinities between Brazilian Indians and other human populations were evaluated by estimates of genetic distance based on haplotype data. The lowest values were observed in relation to Asians, especially Chinese, Polynesians, and Micronesians.

Urban American Indian Aging.

ERIC Educational Resources Information Center

Kramer, Josea

This document begins by dispelling several misperceptions about American Indians that are especially pernicious to older American Indians living in cities, and then goes on to discuss what is known about urban American Indian elders and the implications for planning and service delivery for Area Agencies on Aging and contractor agencies. It notes…

Compound kinetochores of the Indian muntjac. Evolution by linear fusion of unit kinetochores.

PubMed

Brinkley, B R; Valdivia, M M; Tousson, A; Brenner, S L

1984-01-01

The chromosomes of the Indian muntjac (Muntiacus muntjak vaginalis) are unique among mammals due to their low diploid number (2N = 6 female, 7 male) and large size. It has been proposed that the karyotype of this small Asiatic deer evolved from a related deer the Chinese muntjac (Muntiacus reevesi) with a diploid chromosome number of 2n = 46 consisting of small telocentric chromosomes. In this study we utilized a kinetochore-specific antiserum derived from human patients with the autoimmune disease scleroderma CREST as an immunofluorescent probe to examine kinetochores of the two muntjac species. Since CREST antiserum binds to kinetochores of mitotic chromosomes as well as prekinetochores in interphase nuclei, it was possible to identify and compare kinetochore morphology throughout the cell cycle. Our observations indicated that the kinetochores of the Indian muntjac are composed of a linear beadlike array of smaller subunits that become revealed during interphase. The kinetochores of the Chinese muntjac consisted of minute fluorescent dots located at the tips of the 46 telocentric chromosomes. During interphase, however, the kinetochores of the Chinese muntjac clustered into small aggregates reminiscent of the beadlike arrays seen in the Indian muntjac. Morphometric measurements of fluorescence indicated an equivalent amount of stained material in the two species. Our observations indicate that the kinetochores of the Indian muntjac are compound structures composed of linear arrays of smaller units the size of the individual kinetochores seen on metaphase chromosomes of the Chinese muntjac. Our study supports the notion that the kinetochores of the Indian muntjac evolved by linear fusion of unit kinetochores of the Chinese muntjac. Moreover, it is concluded that the evolution of compound kinetochores may have been facilitated by the non-random aggregation of interphase kinetochores in the nuclei of the ancestral species.