Space Experiments with Particle Accelerators (SEPAC)

NASA Technical Reports Server (NTRS)

Obayashi, T.; Kawashima, N.; Kuriki, K.; Nagatomo, M.; Ninomiya, K.; Sasaki, S.; Ushirokawa, A.; Kudo, I.; Ejiri, M.; Roberts, W. T.

1982-01-01

Plans for SEPAC, an instrument array to be used on Spacelab 1 to study vehicle charging and neutralization, beam-plasma interaction in space, beam-atmospheric interaction exciting artificial aurora and airglow, and the electromagnetic-field configuration of the magnetosphere, are presented. The hardware, consisting of electron beam accelerator, magnetoplasma arcjet, neutral-gas plume generator, power supply, diagnostic package (photometer, plasma probes, particle analyzers, and plasma-wave package), TV monitor, and control and data-management unit, is described. The individual SEPAC experiments, the typical operational sequence, and the general outline of the SEPAC follow-on mission are discussed. Some of the experiments are to be joint ventures with AEPI (INS 003) and will be monitored by low-light-level TV.

Metacognitive Monitoring and Dementia: How Intrinsic and Extrinsic Cues Influence Judgments of Learning in People with Alzheimer’s disease

PubMed Central

Thomas, Ayanna K.; Lee, Meeyeon; Balota, David A.

2014-01-01

Objective The present research compared metamemorial monitoring processes among younger adults, non-demented older adults, and older adults diagnosed with early stage Dementia of the Alzheimer’s Type (DAT). Method In three experiments we examined the influence of intrinsic and extrinsic cues on Judgment of Learning (JOL) accuracy. Changes in association strength between cue-target word pairs served as our intrinsic manipulation in Experiments 1 and 2. Changes in encoding orientation served as our extrinsic manipulation in Experiment 3. Results Across all experiments we found that young adults, non-demented older adults, and individuals in the early stages of DAT effectively used intrinsic and extrinsic factors to guide JOL predictions. Conclusions We conclude that while certain aspects of metacognition may be impaired in both the normal and demented older populations, these groups remain able to use theory-based processing, or general knowledge about how memory works, to make metamemory monitoring predictions. PMID:23876118

Exploring Customization in Higher Education: An Experiment in Leveraging Computer Spreadsheet Technology to Deliver Highly Individualized Online Instruction to Undergraduate Business Students

ERIC Educational Resources Information Center

Kunzler, Jayson S.

2012-01-01

This dissertation describes a research study designed to explore whether customization of online instruction results in improved learning in a college business statistics course. The study involved utilizing computer spreadsheet technology to develop an intelligent tutoring system (ITS) designed to: a) collect and monitor individual real-time…

A new device for monitoring individual activity rhythms of honey bees reveals critical effects of the social environment on behavior.

PubMed

Beer, Katharina; Steffan-Dewenter, Ingolf; Härtel, Stephan; Helfrich-Förster, Charlotte

2016-08-01

Chronobiological studies of individual activity rhythms in social insects can be constrained by the artificial isolation of individuals from their social context. We present a new experimental set-up that simultaneously measures the temperature rhythm in a queen-less but brood raising mini colony and the walking activity rhythms of singly kept honey bees that have indirect social contact with it. Our approach enables monitoring of individual bees in the social context of a mini colony under controlled laboratory conditions. In a pilot experiment, we show that social contact with the mini colony improves the survival of monitored young individuals and affects locomotor activity patterns of young and old bees. When exposed to conflicting Zeitgebers consisting of a light-dark (LD) cycle that is phase-delayed with respect to the mini colony rhythm, rhythms of young and old bees are socially synchronized with the mini colony rhythm, whereas isolated bees synchronize to the LD cycle. We conclude that the social environment is a stronger Zeitgeber than the LD cycle and that our new experimental set-up is well suited for studying the mechanisms of social entrainment in honey bees.

Object representations in visual working memory change according to the task context.

PubMed

Balaban, Halely; Luria, Roy

2016-08-01

This study investigated whether an item's representation in visual working memory (VWM) can be updated according to changes in the global task context. We used a modified change detection paradigm, in which the items moved before the retention interval. In all of the experiments, we presented identical color-color conjunction items that were arranged to provide a common fate Gestalt grouping cue during their movement. Task context was manipulated by adding a condition highlighting either the integrated interpretation of the conjunction items or their individuated interpretation. We monitored the contralateral delay activity (CDA) as an online marker of VWM. Experiment 1 employed only a minimal global context; the conjunction items were integrated during their movement, but then were partially individuated, at a late stage of the retention interval. The same conjunction items were perfectly integrated in an integration context (Experiment 2). An individuation context successfully produced strong individuation, already during the movement, overriding Gestalt grouping cues (Experiment 3). In Experiment 4, a short priming of the individuation context managed to individuate the conjunction items immediately after the Gestalt cue was no longer available. Thus, the representations of identical items changed according to the task context, suggesting that VWM interprets incoming input according to global factors which can override perceptual cues. Copyright © 2016 Elsevier Ltd. All rights reserved.

Skylab hardware report operational bioinstrumentation system

NASA Technical Reports Server (NTRS)

Luczkowski, S.

1977-01-01

The Skylab Operational Bioinstrumentation System is a personal, individually adjustable biomedical system designed to monitor the basic physiological functions of each suited crewman during specified periods of a manned space mission. The basic physiological functions of this system include electrocardiogram, respiration by impedance pneumogram, body temperature, cardiotachometer, and subject identification. The Operational Bioinstrumentation System was scheduled to monitor each crewman during launch, extravehicular activities, suited intravehicular experiments, and undocking and return.

Ostracism Reduces Reliance on Poor Advice from Others during Decision Making

PubMed Central

Byrne, Kaileigh A.; Tibbett, Thomas P.; Laserna, Lauren N.; Carter-Sowell, Adrienne R.; Worthy, Darrell A.

2016-01-01

Decision-making is rarely context-free, and often both social information and non-social information are weighed into one’s decisions. Incorporating information into a decision can be influenced by previous experiences. Ostracism has extensive effects, including taxing cognitive resources and increasing social monitoring. In decision-making situations, individuals are often faced with both objective and social information and must choose which information to include or filter out. How will ostracism affect the reliance on objective and social information during decision-making? Participants (N=245) in Experiment 1 were randomly assigned to be included or ostracized in a standardized, group task. They then performed a dynamic decision-making task that involved the presentation of either non-social (i.e. biased reward feedback) or social (i.e., poor advice from a previous participant) misleading information. In Experiment 2, participants (N=105) completed either the ostracism non-social condition or social misleading information condition with explicit instructions stating that the advice given was from an individual who did not partake in the group task. Ostracized individuals relied more on non-social misleading information and performed worse than included individuals. However, ostracized individuals discounted misleading social information and outperformed included individuals. Results of Experiment 2 replicated the findings of Experiment 1. Across two experiments, ostracized individuals were more critical of advice from others, both individuals who may have ostracized them and unrelated individuals. In other words, compared to included individuals, ostracized individuals underweighted advice from another individual, but overweighted non-social information during decision-making. We conclude that when deceptive objective information is present, ostracism results in disadvantageous decision-making. PMID:28469290

Principal Components Analysis of Triaxial Vibration Data From Helicopter Transmissions

NASA Technical Reports Server (NTRS)

Tumer, Irem Y.; Huff, Edward M.

2001-01-01

Research on the nature of the vibration data collected from helicopter transmissions during flight experiments has led to several crucial observations believed to be responsible for the high rates of false alarms and missed detections in aircraft vibration monitoring systems. This work focuses on one such finding, namely, the need to consider additional sources of information about system vibrations. In this light, helicopter transmission vibration data, collected using triaxial accelerometers, were explored in three different directions, analyzed for content, and then combined using Principal Components Analysis (PCA) to analyze changes in directionality. In this paper, the PCA transformation is applied to 176 test conditions/data sets collected from an OH58C helicopter to derive the overall experiment-wide covariance matrix and its principal eigenvectors. The experiment-wide eigenvectors. are then projected onto the individual test conditions to evaluate changes and similarities in their directionality based on the various experimental factors. The paper will present the foundations of the proposed approach, addressing the question of whether experiment-wide eigenvectors accurately model the vibration modes in individual test conditions. The results will further determine the value of using directionality and triaxial accelerometers for vibration monitoring and anomaly detection.

Adults' memories of childhood: true and false reports.

PubMed

Qin, Jianjian; Ogle, Christin M; Goodman, Gail S

2008-12-01

In 3 experiments, the authors examined factors that, according to the source-monitoring framework, might influence false memory formation and true/false memory discernment. In Experiment 1, combined effects of warning and visualization on false childhood memory formation were examined, as were individual differences in true and false childhood memories. Combining warnings and visualization led to the lowest false memory and highest true memory. Several individual difference factors (e.g., parental fearful attachment style) predicted false recall. In addition, true and false childhood memories differed (e.g., in amount of information). Experiment 2 examined relations between Deese/Roediger-McDermott task performance and false childhood memories. Deese/Roediger-McDermott performance (e.g., intrusion of unrelated words in free recall) was associated with false childhood memory, suggesting liberal response criteria in source decisions as a common underlying mechanism. Experiment 3 investigated adults' abilities to discern true and false childhood memory reports (e.g., by detecting differences in amount of information as identified in Experiment 1). Adults who were particularly successful in discerning such reports indicated reliance on event plausibility. Overall, the source-monitoring framework provided a viable explanatory framework. Implications for theory and clinical and forensic interviews are discussed. PsycINFO Database Record (c) 2008 APA, all rights reserved.

Monitoring of benzene-induced hematotoxicity in mice by serial leukocyte counting using a microcavity array.

PubMed

Hosokawa, Masahito; Asami, Marie; Yoshino, Tomoko; Tsujimura, Noriyuki; Takahashi, Masayuki; Nakasono, Satoshi; Tanaka, Tsuyoshi; Matsunaga, Tadashi

2013-02-15

Monitoring of hematotoxicity, which requires serial blood collection, is difficult to carry out in small animals due to a lack of non-invasive, individual animal-appropriate techniques that enable enumeration of leukocyte subsets from limited amounts of whole blood. In this study, a microfluidic device equipped with a microcavity array that enables highly efficient separation of leukocytes from submicroliters of whole blood was applied for hematotoxicity monitoring in mice. The microcavity array can specifically separate leukocytes from whole blood based on differences in the size and deformability between leukocytes and other blood cells. Mouse leukocytes recovered on aligned microcavities were continuously processed for image-based immunophenotypic analysis. Our device successfully recovered almost 100% of mouse leukocytes in 0.1 μL of whole blood without the effect of serial blood collection such as changes in body weight and total leukocyte count. We assessed benzene-associated hematotoxicity in mice using this system. Mice were administered with benzene once daily and the depression of leukocyte numbers induced in individual mice was successfully monitored from tail vein blood collected every other day for 2 weeks. Serial monitoring of the leukocyte number in individual mice will contribute to the understanding of hematotoxicity and reduction of the number of animal experiment trials. Copyright © 2012 Elsevier B.V. All rights reserved.

Working memory predicts the rejection of false memories.

PubMed

Leding, Juliana K

2012-01-01

The relationship between working memory capacity (WMC) and false memories in the memory conjunction paradigm was explored. Previous research using other paradigms has shown that individuals high in WMC are not as likely to experience false memories as low-WMC individuals, the explanation being that high-WMC individuals are better able to engage in source monitoring. In the memory conjunction paradigm participants are presented at study with parent words (e.g., eyeglasses, whiplash). At test, in addition to being presented with targets and foils, participants are presented with lures that are composed of previously studied features (e.g., eyelash). It was found that high-WMC individuals had lower levels of false recognition than low-WMC individuals. Furthermore, recall-to-reject responses were analysed (e.g., "I know I didn't see eyelash because I remember seeing eyeglasses") and it was found that high-WMC individuals were more likely to utilise this memory editing strategy, providing direct evidence that one reason that high-WMC individuals are not as prone to false memories is because they are better able to engage in source monitoring.

The effects of monitoring environment on problem-solving performance.

PubMed

Laird, Brian K; Bailey, Charles D; Hester, Kim

2018-01-01

While effective and efficient solving of everyday problems is important in business domains, little is known about the effects of workplace monitoring on problem-solving performance. In a laboratory experiment, we explored the monitoring environment's effects on an individual's propensity to (1) establish pattern solutions to problems, (2) recognize when pattern solutions are no longer efficient, and (3) solve complex problems. Under three work monitoring regimes-no monitoring, human monitoring, and electronic monitoring-114 participants solved puzzles for monetary rewards. Based on research related to worker autonomy and theory of social facilitation, we hypothesized that monitored (versus non-monitored) participants would (1) have more difficulty finding a pattern solution, (2) more often fail to recognize when the pattern solution is no longer efficient, and (3) solve fewer complex problems. Our results support the first two hypotheses, but in complex problem solving, an interaction was found between self-assessed ability and the monitoring environment.

CLOUDCLOUD : general-purpose instrument monitoring and data managing software

NASA Astrophysics Data System (ADS)

Dias, António; Amorim, António; Tomé, António

2016-04-01

An effective experiment is dependent on the ability to store and deliver data and information to all participant parties regardless of their degree of involvement in the specific parts that make the experiment a whole. Having fast, efficient and ubiquitous access to data will increase visibility and discussion, such that the outcome will have already been reviewed several times, strengthening the conclusions. The CLOUD project aims at providing users with a general purpose data acquisition, management and instrument monitoring platform that is fast, easy to use, lightweight and accessible to all participants of an experiment. This work is now implemented in the CLOUD experiment at CERN and will be fully integrated with the experiment as of 2016. Despite being used in an experiment of the scale of CLOUD, this software can also be used in any size of experiment or monitoring station, from single computers to large networks of computers to monitor any sort of instrument output without influencing the individual instrument's DAQ. Instrument data and meta data is stored and accessed via a specially designed database architecture and any type of instrument output is accepted using our continuously growing parsing application. Multiple databases can be used to separate different data taking periods or a single database can be used if for instance an experiment is continuous. A simple web-based application gives the user total control over the monitored instruments and their data, allowing data visualization and download, upload of processed data and the ability to edit existing instruments or add new instruments to the experiment. When in a network, new computers are immediately recognized and added to the system and are able to monitor instruments connected to them. Automatic computer integration is achieved by a locally running python-based parsing agent that communicates with a main server application guaranteeing that all instruments assigned to that computer are monitored with parsing intervals as fast as milliseconds. This software (server+agents+interface+database) comes in easy and ready-to-use packages that can be installed in any operating system, including Android and iOS systems. This software is ideal for use in modular experiments or monitoring stations with large variability in instruments and measuring methods or in large collaborations, where data requires homogenization in order to be effectively transmitted to all involved parties. This work presents the software and provides performance comparison with previously used monitoring systems in the CLOUD experiment at CERN.

A privacy-strengthened scheme for E-Healthcare monitoring system.

PubMed

Huang, Chanying; Lee, Hwaseong; Lee, Dong Hoon

2012-10-01

Recent Advances in Wireless Body Area Networks (WBANs) offer unprecedented opportunities and challenges to the development of pervasive electronic healthcare (E-Healthcare) monitoring system. In E-Healthcare system, the processed data are patients' sensitive health data that are directly related to individuals' privacy. For this reason, privacy concern is of great importance for E-Healthcare system. Current existing systems for E-Healthcare services, however, have not yet provided sufficient privacy protection for patients. In order to offer adequate security and privacy, in this paper, we propose a privacy-enhanced scheme for patients' physical condition monitoring, which achieves dual effects: (1) providing unlinkability of health records and individual identity, and (2) supporting anonymous authentication and authorized data access. We also conduct a simulation experiment to evaluate the performance of the proposed scheme. The experimental results demonstrate that the proposed scheme achieves better performance in terms of computational complexity, communication overheads and querying efficiency compared with previous results.

STATUS OF TRISO FUEL IRRADIATIONS IN THE ADVANCED TEST REACTOR SUPPORTING HIGH-TEMPERATURE GAS-COOLED REACTOR DESIGNS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davenport, Michael; Petti, D. A.; Palmer, Joe

2016-11-01

The United States Department of Energy’s Advanced Reactor Technologies (ART) Advanced Gas Reactor (AGR) Fuel Development and Qualification Program is irradiating up to seven low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States. The experiments will be irradiated over the next several years to demonstrate and qualify new TRISO coated particle fuel for use in high temperature gas reactors. The goals of the experimentsmore » are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of several independent capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also have on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006 and was completed in November 2009. The second experiment (AGR-2) started irradiation in June 2010 and completed in October 2013. The third and fourth experiments have been combined into a single experiment designated (AGR-3/4), which started its irradiation in December 2011 and completed in April 2014. Since the purpose of this experiment was to provide data on fission product migration and retention in the NGNP reactor, the design of this experiment was significantly different from the first two experiments, though the control and monitoring systems are very similar. The final experiment, AGR-5/6/7, is scheduled to begin irradiation in early summer 2017.« less

Women's experiences of outpatient induction of labour with remote continuous monitoring.

PubMed

O'Brien, Ediri; Rauf, Zubair; Alfirevic, Zarko; Lavender, Tina

2013-04-01

to gain insight into women's experiences and preferences for induction in the home as part of a trial investigating the feasibility and acceptability of outpatient induction of labour with remote monitoring. a qualitative study using semi-structured individual interviews. Interview transcripts were subjected to thematic analysis to identify the dominant themes regarding women's experiences of outpatient induction. a large maternity hospital in the North West of England. fifteen women who participated in the main trial of outpatient induction of labour with remote continuous monitoring. three main themes were identified; the need for women to 'labour within their comfort zone'; their desire to achieve 'the next best thing to a normal labour' and the importance of a 'virtual presence' to offer remote reassurance. women's preference for the outpatient setting of induction of labour is dominated by their need to labour within their comfort zone. Outpatient induction offered women the familiarity and freedom of the home environment, and the resulting physical and emotional comforts helped women cope better with their labour and improved their birth experiences. While remote monitoring offered some reassurance, women still depended on effective communication from hospital staff to provide the virtual presence of a health professional in the home. the combination of slow-release prostaglandin and a remote monitoring device may provide low risk women with an improved induction and labour experience. While ongoing studies continue to explore further the safety of interventions at home, this study has importantly considered women's views and confirmed that induction at home is not only acceptable to women but also that the outpatient experience is preferable to long inpatient inductions. Copyright © 2012 Elsevier Ltd. All rights reserved.

7 CFR 1755.3 - Field trials.

Code of Federal Regulations, 2011 CFR

2011-01-01

... installations of the materials or equipment in closely monitored situations designed to determine, to RUS's... concepts untried within the telephone industry is defined as “an experiment” and shall be handled as a special case using procedures considered appropriate by RUS to meet the individual experiment. (b) To...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, D.E.

This report presents discussions given at a conference on environmental remediation, September 8--11, Pasco, Washington. Topics include: public confidence; education; in-situ remediation; Hanford tank operations; risk assessments; field experiences; standards; site characterization and monitoring; technology discussions; regulatory issues; compliance; and the UMTRA project. Individual projects are processed separately for the data bases.

Standardised Testing: What Space for Professional Judgement?

ERIC Educational Resources Information Center

Doecke, Brenton; Reynolds, Gail; Roberts, Arlene

2002-01-01

Gives an account of Gail Reynolds's experience in administrating the DART (Developmental assessment resource for teachers) and AIM (Achievement improvement monitor) tests at her school. Reflects on how the test results compared with her own judgments of the literacy abilities of individual students in her class. Offers four case studies that draw…

Dreams, reality and memory: confabulations in lucid dreamers implicate reality-monitoring dysfunction in dream consciousness.

PubMed

Corlett, P R; Canavan, S V; Nahum, L; Appah, F; Morgan, P T

2014-01-01

Dreams might represent a window on altered states of consciousness with relevance to psychotic experiences, where reality monitoring is impaired. We examined reality monitoring in healthy, non-psychotic individuals with varying degrees of dream awareness using a task designed to assess confabulatory memory errors - a confusion regarding reality whereby information from the past feels falsely familiar and does not constrain current perception appropriately. Confabulatory errors are common following damage to the ventromedial prefrontal cortex (vmPFC). Ventromedial function has previously been implicated in dreaming and dream awareness. In a hospital research setting, physically and mentally healthy individuals with high (n = 18) and low (n = 13) self-reported dream awareness completed a computerised cognitive task that involved reality monitoring based on familiarity across a series of task runs. Signal detection theory analysis revealed a more liberal acceptance bias in those with high dream awareness, consistent with the notion of overlap in the perception of dreams, imagination and reality. We discuss the implications of these results for models of reality monitoring and psychosis with a particular focus on the role of vmPFC in default-mode brain function, model-based reinforcement learning and the phenomenology of dreaming and waking consciousness.

Effect of collision energy optimization on the measurement of peptides by selected reaction monitoring (SRM) mass spectrometry.

PubMed

Maclean, Brendan; Tomazela, Daniela M; Abbatiello, Susan E; Zhang, Shucha; Whiteaker, Jeffrey R; Paulovich, Amanda G; Carr, Steven A; Maccoss, Michael J

2010-12-15

Proteomics experiments based on Selected Reaction Monitoring (SRM, also referred to as Multiple Reaction Monitoring or MRM) are being used to target large numbers of protein candidates in complex mixtures. At present, instrument parameters are often optimized for each peptide, a time and resource intensive process. Large SRM experiments are greatly facilitated by having the ability to predict MS instrument parameters that work well with the broad diversity of peptides they target. For this reason, we investigated the impact of using simple linear equations to predict the collision energy (CE) on peptide signal intensity and compared it with the empirical optimization of the CE for each peptide and transition individually. Using optimized linear equations, the difference between predicted and empirically derived CE values was found to be an average gain of only 7.8% of total peak area. We also found that existing commonly used linear equations fall short of their potential, and should be recalculated for each charge state and when introducing new instrument platforms. We provide a fully automated pipeline for calculating these equations and individually optimizing CE of each transition on SRM instruments from Agilent, Applied Biosystems, Thermo-Scientific and Waters in the open source Skyline software tool ( http://proteome.gs.washington.edu/software/skyline ).

Ant workers exhibit specialization and memory during raft formation.

PubMed

Avril, Amaury; Purcell, Jessica; Chapuisat, Michel

2016-06-01

By working together, social insects achieve tasks that are beyond the reach of single individuals. A striking example of collective behaviour is self-assembly, a process in which individuals link their bodies together to form structures such as chains, ladders, walls or rafts. To get insight into how individual behavioural variation affects the formation of self-assemblages, we investigated the presence of task specialization and the role of past experience in the construction of ant rafts. We subjected groups of Formica selysi workers to two consecutive floods and monitored the position of individuals in rafts. Workers showed specialization in their positions when rafting, with the same individuals consistently occupying the top, middle, base or side position in the raft. The presence of brood modified workers' position and raft shape. Surprisingly, workers' experience in the first rafting trial with brood influenced their behaviour and raft shape in the subsequent trial without brood. Overall, this study sheds light on the importance of workers' specialization and memory in the formation of self-assemblages.

Ant workers exhibit specialization and memory during raft formation

NASA Astrophysics Data System (ADS)

Avril, Amaury; Purcell, Jessica; Chapuisat, Michel

2016-06-01

By working together, social insects achieve tasks that are beyond the reach of single individuals. A striking example of collective behaviour is self-assembly, a process in which individuals link their bodies together to form structures such as chains, ladders, walls or rafts. To get insight into how individual behavioural variation affects the formation of self-assemblages, we investigated the presence of task specialization and the role of past experience in the construction of ant rafts. We subjected groups of Formica selysi workers to two consecutive floods and monitored the position of individuals in rafts. Workers showed specialization in their positions when rafting, with the same individuals consistently occupying the top, middle, base or side position in the raft. The presence of brood modified workers' position and raft shape. Surprisingly, workers' experience in the first rafting trial with brood influenced their behaviour and raft shape in the subsequent trial without brood. Overall, this study sheds light on the importance of workers' specialization and memory in the formation of self-assemblages.

Action video gaming and cognitive control: playing first person shooter games is associated with improvement in working memory but not action inhibition.

PubMed

Colzato, Lorenza S; van den Wildenberg, Wery P M; Zmigrod, Sharon; Hommel, Bernhard

2013-03-01

The interest in the influence of videogame experience in our daily life is constantly growing. "First Person Shooter" (FPS) games require players to develop a flexible mindset to rapidly react and monitor fast moving visual and auditory stimuli, and to inhibit erroneous actions. This study investigated whether and to which degree experience with such videogames generalizes to other cognitive control tasks. Experienced video game players (VGPs) and individuals with little to no videogame experience (NVGPs) performed on a N-back task and a stop-signal paradigm that provide a relatively well-established diagnostic measure of the monitoring and updating of working memory (WM) and response inhibition (an index of behavioral impulsivity), respectively. VGPs were faster and more accurate in the monitoring and updating of WM than NVGPs, which were faster in reacting to go signals, but showed comparable stopping performance. Our findings support the idea that playing FPS games is associated with enhanced flexible updating of task-relevant information without affecting impulsivity.

Health disparities monitoring in the U.S.: lessons for monitoring efforts in Israel and other countries.

PubMed

Abu-Saad, Kathleen; Avni, Shlomit; Kalter-Leibovici, Ofra

2018-02-28

Health disparities are a persistent problem in many high-income countries. Health policymakers recognize the need to develop systematic methods for documenting and tracking these disparities in order to reduce them. The experience of the U.S., which has a well-established health disparities monitoring infrastructure, provides useful insights for other countries. This article provides an in-depth review of health disparities monitoring in the U.S. Lessons of potential relevance for other countries include: 1) the integration of health disparities monitoring in population health surveillance, 2) the role of political commitment, 3) use of monitoring as a feedback loop to inform future directions, 4) use of monitoring to identify data gaps, 5) development of extensive cross-departmental cooperation, and 6) exploitation of digital tools for monitoring and reporting. Using Israel as a case in point, we provide a brief overview of the healthcare and health disparities landscape in Israel, and examine how the lessons from the U.S. experience might be applied in the Israeli context. The U.S. model of health disparities monitoring provides useful lessons for other countries with respect to documentation of health disparities and tracking of progress made towards their elimination. Given the persistence of health disparities both in the U.S. and Israel, there is a need for monitoring systems to expand beyond individual- and healthcare system-level factors, to incorporate social and environmental determinants of health as health indicators/outcomes.

Effects of decades of physical driving on body movement and motion sickness during virtual driving

PubMed Central

Chang, Chih-Hui; Chen, Fu-Chen; Zeng, Wei-Jhong

2017-01-01

We investigated relations between experience driving physical automobiles and motion sickness during the driving of virtual automobiles. Middle-aged individuals drove a virtual automobile in a driving video game. Drivers were individuals who had possessed a driver’s license for approximately 30 years, and who drove regularly, while non-drivers were individuals who had never held a driver’s license, or who had not driven for more than 15 years. During virtual driving, we monitored movement of the head and torso. During virtual driving, drivers became motion sick more rapidly than non-drivers, but the incidence and severity of motion sickness did not differ as a function of driving experience. Patterns of movement during virtual driving differed as a function of driving experience. Separately, movement differed between participants who later became motion sick and those who did not. Most importantly, physical driving experience influenced patterns of postural activity that preceded motion sickness during virtual driving. The results are consistent with the postural instability theory of motion sickness, and help to illuminate relations between the control of physical and virtual vehicles. PMID:29121059

Judgments of Learning are Influenced by Multiple Cues In Addition to Memory for Past Test Accuracy.

PubMed

Hertzog, Christopher; Hines, Jarrod C; Touron, Dayna R

When people try to learn new information (e.g., in a school setting), they often have multiple opportunities to study the material. One of the most important things to know is whether people adjust their study behavior on the basis of past success so as to increase their overall level of learning (for example, by emphasizing information they have not yet learned). Monitoring their learning is a key part of being able to make those kinds of adjustments. We used a recognition memory task to replicate prior research showing that memory for past test outcomes influences later monitoring, as measured by judgments of learning (JOLs; confidence that the material has been learned), but also to show that subjective confidence in whether the test answer and the amount of time taken to restudy the items also have independent effects on JOLs. We also show that there are individual differences in the effects of test accuracy and test confidence on JOLs, showing that some but not all people use past test experiences to guide monitoring of their new learning. Monitoring learning is therefore a complex process of considering multiple cues, and some people attend to those cues more effectively than others. Improving the quality of monitoring performance and learning could lead to better study behaviors and better learning. An individual's memory of past test performance (MPT) is often cited as the primary cue for judgments of learning (JOLs) following test experience during multi-trial learning tasks (Finn & Metcalfe, 2007; 2008). We used an associative recognition task to evaluate MPT-related phenomena, because performance monitoring, as measured by recognition test confidence judgments (CJs), is fallible and varies in accuracy across persons. The current study used multilevel regression models to show the simultaneous and independent influences of multiple cues on Trial 2 JOLs, in addition to performance accuracy (the typical measure of MPT in cued-recall experiments). These cues include recognition CJs, perceived recognition fluency, and Trial 2 study time allocation (an index of reprocessing fluency). Our results expand the scope of MPT-related phenomena in recognition memory testing to show independent effects of recognition test accuracy and CJs on second-trial JOLs, while also demonstrating individual differences in the effects of these cues on JOLs (as manifested in significant random effects for those regression effects in the model). The effect of study time on second-trial JOLs controlling on other variables, including Trial 1 recognition memory accuracy, also demonstrates that second-trial encoding behavior influence JOLs in addition to MPT.

Foam Experiment Hardware are Flown on Microgravity Rocket MAXUS 4

NASA Astrophysics Data System (ADS)

Lockowandt, C.; Löth, K.; Jansson, O.; Holm, P.; Lundin, M.; Schneider, H.; Larsson, B.

2002-01-01

The Foam module was developed by Swedish Space Corporation and was used for performing foam experiments on the sounding rocket MAXUS 4 launched from Esrange 29 April 2001. The development and launch of the module has been financed by ESA. Four different foam experiments were performed, two aqueous foams by Doctor Michele Adler from LPMDI, University of Marne la Vallée, Paris and two non aqueous foams by Doctor Bengt Kronberg from YKI, Institute for Surface Chemistry, Stockholm. The foam was generated in four separate foam systems and monitored in microgravity with CCD cameras. The purpose of the experiment was to generate and study the foam in microgravity. Due to loss of gravity there is no drainage in the foam and the reactions in the foam can be studied without drainage. Four solutions with various stabilities were investigated. The aqueous solutions contained water, SDS (Sodium Dodecyl Sulphate) and dodecanol. The organic solutions contained ethylene glycol a cationic surfactant, cetyl trimethyl ammonium bromide (CTAB) and decanol. Carbon dioxide was used to generate the aqueous foam and nitrogen was used to generate the organic foam. The experiment system comprised four complete independent systems with injection unit, experiment chamber and gas system. The main part in the experiment system is the experiment chamber where the foam is generated and monitored. The chamber inner dimensions are 50x50x50 mm and it has front and back wall made of glass. The front window is used for monitoring the foam and the back window is used for back illumination. The front glass has etched crosses on the inside as reference points. In the bottom of the cell is a glass frit and at the top is a gas in/outlet. The foam was generated by injecting the experiment liquid in a glass frit in the bottom of the experiment chamber. Simultaneously gas was blown through the glass frit and a small amount of foam was generated. This procedure was performed at 10 bar. Then the pressure was lowered in the experiment chamber to approximately 0,1 bar to expand the foam to a dry foam that filled the experiment chamber. The foam was regenerated during flight by pressurise the cell and repeat the foam generation procedures. The module had 4 individual experiment chambers for the four different solutions. The four experiment chambers were controlled individually with individual experiment parameters and procedures. The gas system comprise on/off valves and adjustable valves to control the pressure and the gas flow and liquid flow during foam generation. The gas system can be divided in four sections, each section serving one experiment chamber. The sections are partly connected in two pairs with common inlet and outlet. The two pairs are supplied with a 1l gas bottle each filled to a pressure of 40 bar and a pressure regulator lowering the pressure from 40 bar to 10 bar. Two sections are connected to the same outlet. The gas outlets from the experiment chambers are connected to two symmetrical placed outlets on the outer structure with diffusers not to disturb the g-levels. The foam in each experiment chamber was monitored with one tomography camera and one overview camera (8 CCD cameras in total). The tomography camera is placed on a translation table which makes it possible to move it in the depth direction of the experiment chamber. The video signal from the 8 CCD cameras were stored onboard with two DV recorders. Two video signals were also transmitted to ground for real time evaluation and operation of the experiment. Which camera signal that was transmitted to ground could be selected with telecommands. With help of the tomography system it was possible to take sequences of images of the foam at different depths in the foam. This sequences of images are used for constructing a 3-D model of the foam after flight. The overview camera has a fixed position and a field of view that covers the total experiment chamber. This camera is used for monitoring the generation of foam and the overall behaviour of the foam. The experiment was performed successfully with foam generation in all 4 experiment chambers. Foam was also regenerated during flight with telecommands. The experiment data is under evaluation.

Attribution of movement: Potential links between subjective reports of agency and output monitoring.

PubMed

Sugimori, Eriko; Asai, Tomohisa

2015-01-01

According to agency memory theory, individuals decide whether "I did it" based on a memory trace of "I am doing it". The purpose of this study was to validate the agency memory theory. To this end, several hand actions were individually presented as samples, and participants were asked to perform the sample action, observe the performance of that action by another person, or imagine performing the action. Online feedback received by the participants during the action was manipulated among the different conditions, and output monitoring, in which participants were asked whether they had performed each hand action, was conducted. The rate at which respondents thought that they themselves had performed the action was higher when visual feedback was unaltered than when it was altered (Experiment 1A), and this tendency was observed across all types of altered feedback (Experiment 1B). The observation of an action performed by the hand of another person did not increase the rate at which respondents thought that they themselves had performed the action unless the participants actually did perform the action (Experiments 2A and 2B). In Experiment 3, a relationship was observed between the subjective feeling that "I am the one who is causing an action" and the memory that "I did perform the action". These experiments support the hypothesis that qualitative information and sense of "self" are tagged in a memory trace and that such tags can be used as cues for judgements when the memory is related to the "self".

Victimization and Relational Aggression in Adolescent Romantic Relationships: The Influence of Parental and Peer Behaviors, and Individual Adjustment

PubMed Central

Leadbeater, Bonnie J.; Ellis, Wendy E.; Yeung, Rachel

2016-01-01

Consistent with the view that adolescent relationships are established in the context of important characteristics of their social networks, we examined the effects of adolescents’ experiences of parenting (psychological control and positive monitoring) and of peer aggression and victimization, on their self reports of dating victimization and aggression. We also examined the effects of individual differences in emotional and behavioral problems. We used questionnaire data from a population-based sample of youth 12–18 years old who were in dating relationships (n = 149). Parental monitoring emerged as a protective factor in reducing both dating victimization and relational aggression. Our findings also point to a significant transfer of aggression in peer relationships to relational aggression in dating relationships. PMID:27307651

Context cue focality influences strategic prospective memory monitoring.

PubMed

Hunter Ball, B; Bugg, Julie M

2018-02-12

Monitoring the environment for the occurrence of prospective memory (PM) targets is a resource-demanding process that produces cost (e.g., slower responding) to ongoing activities. However, research suggests that individuals are able to monitor strategically by using contextual cues to reduce monitoring in contexts in which PM targets are not expected to occur. In the current study, we investigated the processes supporting context identification (i.e., determining whether or not the context is appropriate for monitoring) by testing the context cue focality hypothesis. This hypothesis predicts that the ability to monitor strategically depends on whether the ongoing task orients attention to the contextual cues that are available to guide monitoring. In Experiment 1, participants performed an ongoing lexical decision task and were told that PM targets (TOR syllable) would only occur in word trials (focal context cue condition) or in items starting with consonants (nonfocal context cue condition). In Experiment 2, participants performed an ongoing first letter judgment (consonant/vowel) task and were told that PM targets would only occur in items starting with consonants (focal context cue condition) or in word trials (nonfocal context cue condition). Consistent with the context cue focality hypothesis, strategic monitoring was only observed during focal context cue conditions in which the type of ongoing task processing automatically oriented attention to the relevant features of the contextual cue. These findings suggest that strategic monitoring is dependent on limited-capacity processing resources and may be relatively limited when the attentional demands of context identification are sufficiently high.

Dynamics of response-conflict monitoring and individual differences in response control and behavioral control: an electrophysiological investigation using a stop-signal task.

PubMed

Stahl, Jutta; Gibbons, Henning

2007-03-01

The aim of the present study was to investigate the functional significance of error (related) negativity Ne/ERN and individual differences in human action monitoring. A response-conflict model of Ne/ERN should be tested applying a stop-signal paradigm. After a few modifications of Ne/ERN response-conflict theory (Yeung N, Botvinick MM, Cohen JD. The neural basis of error detection: conflict monitoring and the error-related negativity. Psychological Review 2004:111(4);931-959), strength and time course of response conflict could be modeled as a function of stop-signal delay. In Experiment 1, 35 participants performed a visual two-choice response-time task but tried to withhold the response if an auditory stop signal was presented. Probability of stopping errors was held at 50% using variable delays between visual and auditory stimuli. Experiment 2 (n=10) employed both auditory go and stop signals and confirmed that Ne/ERN effects are due to conflict induced by the auditory stop signal, and not the mere presence or absence of an additional stimulus. As predicted, amplitudes of both the stimulus-locked and response-locked Ne/ERN were largest for non-stopped responses, followed by successfully stopped and go responses. However, independently of response type Ne/ERN also increased with increasing stop-signal delay. Since longer delay invokes stronger response conflict, results specifically support the notion of Ne/ERN reflecting response-conflict monitoring. Furthermore, individual differences related to measures of response control and behavioral control were observed. Both low response control estimated from stop-task performance and high psychometric impulsivity were accompanied by smaller Ne/ERN amplitude on stop trials, suggesting reduced response-conflict monitoring. The present study supported the response-conflict view of Ne/ERN. Furthermore, the observed relationship between impulsivity and Ne/ERN amplitude suggested that individuals with low behavioral control were characterized by lower activity in anterior cingulate cortex, the neural generator of Ne/ERN, in situations of strong response conflict. The present study, for the first time, employed a stop-signal paradigm to verify predictions regarding the temporal dynamics of response-conflict processing as derived from response-conflict theory of ERN.

Spiral Bevel Gear Damage Detection Using Decision Fusion Analysis

NASA Technical Reports Server (NTRS)

Dempsey, Paula J.; Handschuh, Robert F.; Afjeh, Abdollah A.

2002-01-01

A diagnostic tool for detecting damage to spiral bevel gears was developed. Two different monitoring technologies, oil debris analysis and vibration, were integrated using data fusion into a health monitoring system for detecting surface fatigue pitting damage on gears. This integrated system showed improved detection and decision-making capabilities as compared to using individual monitoring technologies. This diagnostic tool was evaluated by collecting vibration and oil debris data from fatigue tests performed in the NASA Glenn Spiral Bevel Gear Fatigue Rigs. Data was collected during experiments performed in this test rig when pitting damage occurred. Results show that combining the vibration and oil debris measurement technologies improves the detection of pitting damage on spiral bevel gears.

Patients' and caregivers' experiences of using continuous glucose monitoring to support diabetes self-management: qualitative study.

PubMed

Lawton, J; Blackburn, M; Allen, J; Campbell, F; Elleri, D; Leelarathna, L; Rankin, D; Tauschmann, M; Thabit, H; Hovorka, R

2018-02-20

Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access historical data to inform treatment decisions. While the clinical and psychological benefits of CGM are well established, little is known about how individuals use CGM to inform diabetes self-management. We explored participants' experiences of using CGM in order to provide recommendations for supporting individuals to make optimal use of this technology. In-depth interviews (n = 24) with adults, adolescents and parents who had used CGM for ≥4 weeks; data were analysed thematically. Participants found CGM an empowering tool because they could access blood glucose data effortlessly, and trend arrows enabled them to see whether blood glucose was rising or dropping and at what speed. This predicative information aided short-term lifestyle planning and enabled individuals to take action to prevent hypoglycaemia and hyperglycaemia. Having easy access to blood glucose data on a continuous basis also allowed participants to develop a better understanding of how insulin, activity and food impacted on blood glucose. This understanding was described as motivating individuals to make dietary changes and break cycles of over-treating hypoglycaemia and hyperglycaemia. Participants also described how historical CGM data provided a more nuanced picture of blood glucose control than was possible with blood glucose self-monitoring and, hence, better information to inform changes to background insulin doses and mealtime ratios. However, while participants expressed confidence making immediate adjustments to insulin and lifestyle to address impending hypoglycaemia and hypoglycaemia, most described needing and expecting health professionals to interpret historical CGM data and determine changes to background insulin doses and mealtime ratios. While alarms could reinforce a sense of hypoglycaemic safety, some individuals expressed ambivalent views, especially those who perceived alarms as signalling personal failure to achieve optimal glycaemic control. CGM can be an empowering and motivational tool which enables participants to fine-tune and optimize their blood glucose control. However, individuals may benefit from psycho-social education, training and/or technological support to make optimal use of CGM data and use alarms appropriately.

Dreams, reality and memory: confabulations in lucid dreamers implicate reality-monitoring dysfunction in dream consciousness

PubMed Central

Corlett, P.R.; Canavan, S.V.; Nahum, L.; Appah, F.; Morgan, P.T.

2014-01-01

Introduction. Dreams might represent a window on altered states of consciousness with relevance to psychotic experiences, where reality monitoring is impaired. We examined reality monitoring in healthy, non-psychotic individuals with varying degrees of dream awareness using a task designed to assess confabulatory memory errors – a confusion regarding reality whereby information from the past feels falsely familiar and does not constrain current perception appropriately. Confabulatory errors are common following damage to the ventromedial prefrontal cortex (vmPFC). Ventromedial function has previously been implicated in dreaming and dream awareness. Methods. In a hospital research setting, physically and mentally healthy individuals with high (n = 18) and low (n = 13) self-reported dream awareness completed a computerised cognitive task that involved reality monitoring based on familiarity across a series of task runs. Results. Signal detection theory analysis revealed a more liberal acceptance bias in those with high dream awareness, consistent with the notion of overlap in the perception of dreams, imagination and reality. Conclusions. We discuss the implications of these results for models of reality monitoring and psychosis with a particular focus on the role of vmPFC in default-mode brain function, model-based reinforcement learning and the phenomenology of dreaming and waking consciousness. PMID:25028078

Technical note: Mining data from on-farm electronic equipment to identify the time dairy cows spend away from the pen.

PubMed

Thompson, A J; Weary, D M; von Keyserlingk, M A G

2017-05-01

The electronic equipment used on farms can be creatively co-opted to collect data for which it was not originally designed. In the current study, we describe 2 novel algorithms that harvest data from electronic feeding equipment and data loggers used to record standing and lying behavior, to estimate the time that dairy cows spend away from their pen to be milked. Our 2 objectives were to (1) measure the ability of the first algorithm to estimate the time cows spend away from the pen as a group and (2) determine the capability of a second algorithm to estimate the time it takes for individual cows to return to their pen after being milked. To achieve these objectives, we conducted 2 separate experiments: first, to estimate group time away, the feeding behavior of 1 pen of 20 Holstein cows was monitored electronically for 1 mo; second, to measure individual latency to return to the pen, feeding and lying behavior of 12 healthy Holstein cows was monitored electronically from parturition to 21 d in milk. For both experiments, we monitored the time each individual cow exited the pen before each milking and when she returned to the pen after milking using video recordings. Estimates generated by our algorithms were then compared with the times captured from the video recordings. Our first algorithm provided reliable pen-based estimates for the minimum time cows spent away from the pen to be milked in the morning [coefficient of determination (R 2 ) = 0.92] and afternoon (R 2 = 0.96). The second algorithm was able to estimate of the time it took for individual cows to return to the pen after being milked in the morning (R 2 = 0.98), but less so in the afternoon (R 2 = 0.67). This study illustrates how data from electronic systems used to assess feeding and lying behavior can be mined to estimate novel measures. New work is now required to improve the estimates of our algorithm for individuals, for example by adding data from other electronic monitoring systems on the farm. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Professional figures in intermediate intensive units.

PubMed

Quadri, A; Simoni, P; Clini, E; Errera, D; Foglio, K; Vitacca, M; Schena, M

1994-12-01

In Italy, respiratory intermediate intensive care units (IICUs) are not yet considered as autonomous hospital departments. The IICU of the Rehabilitation Department of the Medical Centre of Gussago (12 monitored beds) provides care for respiratory and cardiac patients. Ventilatory assistance and noninvasive modalities both in treatment and monitoring suggest a multidisciplinary approach to the patient. Highly professional figures should, therefore, be singled out to provide care in a respiratory IICU. The medical staff is composed of one anaesthesiologist, one cardiologist and one pulmonologist, who can integrate care when respiratory complications occur in a cardiological patient, or when cardiac events affect a respiratory patient. Nurses are capable of specific activities, especially when ventilatory assistance is required. The presence of a physiotherapist reduces the nursing workload, especially for ventilated individuals. The psychological aspect is undertaken by a specialist. Finally, an expert in nutrition provides an individualized dietary regimen. Our 4 year experience encourages such a multidisciplinary approach. An ideal integration of the professional activities should provide adequate and individual care for patients admitted to an IICU.

Trends and individual differences in response to short-haul flight operations

NASA Technical Reports Server (NTRS)

Chidester, Thomas R.

1990-01-01

A survey of airline pilots was undertaken to determine normative patterns and individual differences in mood and sleep during short-haul flight operations. The results revealed that over the course of a typical 2-d trip, pilots experience a decline in positive mood, or activity, and an increase in negative mood, or tension. On layovers, pilots report experiencing sleep of shorter duration and poorer quality than at home. These patterns are very similar to those reported by Gander and Graeber (1987) and by Gander et al. (1988), using high-fidelity sleep and activity monitoring equipment. Examination of the impact of two personality dimensions extracted from the Jenkins Activity Survey measure of the Type A personality, Achievement Striving and Impatience/Irritability, suggested that Impatience/Irritability may serve as a marker of individuals most likely to experience health-related problems on trips. Achievement Striving may serve as a predictor of performance in crew settings.

Trends and individual differences in response to short-haul fight operations

NASA Technical Reports Server (NTRS)

Chidester, T. R.

1990-01-01

A survey of airline pilots was undertaken to determine normative patterns and individual differences in mood and sleep during short-haul flight operations. The results revealed that over the course of a typical 2-d trip, pilots experience a decline in positive mood, or activity, and an increase in negative mood, or tension. On layovers, pilots report experiencing sleep of shorter duration and poorer quality than at home. These patterns are very similar to those reported by Gander and Graeber and by Gander et al. using high-fidelity sleep and activity monitoring equipment. Examination of the impact of two personality dimensions extracted from the Jenkins Activity Survey measure of the Type A personality, Achievement Striving and Impatience/Irritability, suggested that Impatience/Irritability may serve as a marker of individuals most likely to experience health-related problems on trips. Achievement Striving may serve as a predictor of performance in crew settings.

Retrieval Experience as a Modifier of Future Encoding: Another Test Effect

ERIC Educational Resources Information Center

Bjork, Elizabeth Ligon; Storm, Benjamin C.

2011-01-01

Research on how individuals monitor their level of comprehension during study paints a picture of learners as being insensitive to many of the factors or conditions of learning that can enhance long-term retention and transfer. In previous research, however, deWinstanley and Bjork (2004) demonstrated that learners--if made sensitive to the…

Investigating the Mechanism of Heteroaromatic Decarboxylation Using Solvent Kinetic Isotope Effects and Eyring Transition-State Theory

ERIC Educational Resources Information Center

Mundle, Scott O. C.; Opinska, Liliana Guevara; Kluger, Ronald; Dicks, Andrew P.

2011-01-01

An upper-level mechanistic organic experiment is outlined where undergraduates measure kinetic rate constants for decarboxylation of pyrrole-2-carboxylic acid by the initial-rates method. UV spectroscopy is used to monitor reactant disappearance in both hydrochloric acid and deuterium chloride at different temperatures. Individual data are pooled…

Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative.

PubMed

Calis, Karim A; Archdeacon, Patrick; Bain, Raymond; DeMets, David; Donohue, Miriam; Elzarrad, M Khair; Forrest, Annemarie; McEachern, John; Pencina, Michael J; Perlmutter, Jane; Lewis, Roger J

2017-08-01

Background/aims Use of data monitoring committees to oversee clinical trials was first proposed nearly 50 years ago. Since then, data monitoring committee use in clinical trials has increased and evolved. Nonetheless, there are no well-defined criteria for determining the need for a data monitoring committee, and considerable variability exists in data monitoring committee composition and conduct. To understand and describe the role and function of data monitoring committees, and establish best practices for data monitoring committee trial oversight, the Clinical Trials Transformation Initiative-a public-private partnership to improve clinical trials-launched a multi-stakeholder project. Methods The data monitoring committee project team included 16 individuals charged with (1) clarifying the purpose of data monitoring committees, (2) identifying best practices for independent data monitoring committee conduct, (3) describing effective communication practices, and (4) developing strategies for training data monitoring committee members. Evidence gathering included a survey, a series of focus group discussions, and a 2-day expert meeting aimed at achieving consensus opinions that form the foundation of our data monitoring committee recommendations. Results We define the role of the data monitoring committee as an advisor to the research sponsor on whether to continue, modify, or terminate a trial based on periodic assessment of trial data. Data monitoring committees should remain independent from the sponsor and be composed of members with no relevant conflicts of interest. Representation on a data monitoring committee generally should include at least one clinician with expertise in the therapeutic area being studied, a biostatistician, and a designated chairperson who has experience with clinical trials and data monitoring. Data monitoring committee meetings are held periodically to evaluate the unmasked data from ongoing trials, but the content and conduct of meetings may vary depending on specific goals or topics for deliberation. To guide data monitoring committee conduct and communication plans, a charter consistent with the protocol's research design and statistical analysis plan should be developed and agreed upon by the sponsor and the data monitoring committee prior to patient enrollment. We recommend concise and flexible charters that explain roles, responsibilities, operational issues, and how data monitoring committee recommendations are generated and communicated. The demand for data monitoring committee members appears to exceed the current pool of qualified individuals. To prepare a new generation of trained data monitoring committee members, we encourage a combination of didactic educational programs, practical experience, and skill development through apprenticeships and mentoring by experienced data monitoring committee members. Conclusion Our recommendations address data monitoring committee use, conduct, communication practices, and member preparation and training. Furthermore recommendations form the foundation for ongoing efforts to improve clinical trial oversight and enhance the safety and integrity of clinical research. These recommendations serve as a call to action for implementation of best practices that benefit study participants, study sponsors, and society.

Participant experiences in a smartphone-based health coaching intervention for type 2 diabetes: A qualitative inquiry.

PubMed

Pludwinski, Sarah; Ahmad, Farah; Wayne, Noah; Ritvo, Paul

2016-04-01

We investigated the experience of individuals diagnosed with type 2 diabetes mellitus (T2DM) who participated in an intervention in which the key elements were the provision of a smartphone and self-monitoring software. The interviews focused on use of a smartphone and the effects on motivation for health behavior change. This was a qualitative evaluation of participants in a larger T2DM self-management randomized controlled trial (RCT) conducted at the Black Creek Community Health Centre (BCCHC) in Toronto, Canada (ClinicalTrials.gov Identifier: NCT02036892). The study is based on semi-structured interviews (n = 11) that were audio taped and analyzed with a thematic analytic approach. The RCT compared the effectiveness of six months of smartphone-based self-monitoring and health coaching with a control group who received health coaching without internet or smartphone-based assistance. Qualitative data analyses resulted in derivation of four major themes that describe participant experience: (a) 'smartphone and software', describes smartphone use in relation to health behavior change; (b) 'health coach' describes how client/health coach relationships were assisted by smartphone use; (c) 'overall experience' describes perceptions of the overall intervention; and (d) 'frustrations in managing chronic conditions' describes difficulties with the complexities of T2DM management from a patient perspective. Findings suggest that interventions with T2DM assisted by smartphone software and health coaches actively engage individuals in improved hemoglobin A1c (HbA1c) control. © The Author(s) 2015.

[Effects of situational and individual variables on critical thinking expression].

PubMed

Tanaka, Yuko; Kusumi, Takashi

2016-04-01

The present study examined when people decide to choose an expression that is based on critical thinking, and how situational and individual variables affect such a decision process. Given a conversation scenario including overgeneralization with two friends, participants decided whether to follow the conversation by a critical-thinking expression or not. The authors controlled purpose and topic as situational variables, and measured critical-thinking ability, critical-thinking disposition, and self-monitoring as individual variables. We conducted an experiment in which the situational variables were counterbalanced in a within-subject design with 60 university students. The results of logistic regression analysis showed differences within individuals in the decision process whether to choose a critical-thinking expression, and that some situational factors and some subscales of the individual measurements were related to the differences.

Transcutaneous blood glucose monitoring system based on an ISFET glucose sensor and studies on diabetic patients.

PubMed

Ito, N; Saito, A; Kayashima, S; Kimura, J; Kuriyama, T; Nagata, N; Arai, T; Kikuchi, M

1995-01-01

A transcutaneous blood glucose monitoring system consists of an ion-sensitive field-effect transistor (ISFET) glucose sensor unit and a suction effusion fluid (SEF) collecting unit. The SEF is directly collected by a weak suction (400 mmHg absolute pressure) through the skin from which the corneum layer of the epidermis has been previously removed. An ISFET glucose sensor unit is able to measure glucose concentrations in a microliter order sampling volume. The system was applied to three diabetic patients during a 75 g oral glucose tolerance test for monitoring blood glucose levels. During the experiments, glucose changes in the SEF followed actual blood glucose levels with 10 min delays. Results suggest the feasibility of utilizing quasi-continuous, transcutaneous blood glucose monitoring for individual patients with various diabetic histories or diabetic complications.

Perceived trustworthiness shapes neural empathic responses toward others' pain.

PubMed

Sessa, Paola; Meconi, Federica

2015-12-01

As might be expected, neural empathic responses toward someone in pain are shaped by the affective/social relationship between the observer and the suffering person. Brain activity associated with empathy is sensitive to previous knowledge on the other's social conduct, such that, for instance, an unfair person in pain elicits in the observer reduced activations of empathy-related brain regions compared to a fair person. We conjectured that even in the absence of information on the personality and social behavior of an individual, empathy might be modulated by the 'first impression' based on other's physical facial features, such that the other is perceived as trustworthy or untrustworthy. By means of event-related potentials technique, we monitored in two experiments the neural empathic responses associated with the pain of trustworthy and untrustworthy faces, either computerized and parametrically manipulated (Experiment 1) and real faces (Experiment 2) in a cue-based paradigm. We observed P3 empathic reactions towards individuals looking trustworthy whereas the reactions towards individuals looking untrustworthy were negligible, if not null. An additional experiment (Experiment 3) was conducted in order to substantiate our conclusions by demonstrating that the experimental paradigm we designed did very likely activate an empathic response. Copyright © 2015 Elsevier Ltd. All rights reserved.

Virtual reality hardware and graphic display options for brain-machine interfaces

PubMed Central

Marathe, Amar R.; Carey, Holle L.; Taylor, Dawn M.

2009-01-01

Virtual reality hardware and graphic displays are reviewed here as a development environment for brain-machine interfaces (BMIs). Two desktop stereoscopic monitors and one 2D monitor were compared in a visual depth discrimination task and in a 3D target-matching task where able-bodied individuals used actual hand movements to match a virtual hand to different target hands. Three graphic representations of the hand were compared: a plain sphere, a sphere attached to the fingertip of a realistic hand and arm, and a stylized pacman-like hand. Several subjects had great difficulty using either stereo monitor for depth perception when perspective size cues were removed. A mismatch in stereo and size cues generated inappropriate depth illusions. This phenomenon has implications for choosing target and virtual hand sizes in BMI experiments. Target matching accuracy was about as good with the 2D monitor as with either 3D monitor. However, users achieved this accuracy by exploring the boundaries of the hand in the target with carefully controlled movements. This method of determining relative depth may not be possible in BMI experiments if movement control is more limited. Intuitive depth cues, such as including a virtual arm, can significantly improve depth perception accuracy with or without stereo viewing. PMID:18006069

Working memory capacity may influence perceived effort during aided speech recognition in noise.

PubMed

Rudner, Mary; Lunner, Thomas; Behrens, Thomas; Thorén, Elisabet Sundewall; Rönnberg, Jerker

2012-09-01

Recently there has been interest in using subjective ratings as a measure of perceived effort during speech recognition in noise. Perceived effort may be an indicator of cognitive load. Thus, subjective effort ratings during speech recognition in noise may covary both with signal-to-noise ratio (SNR) and individual cognitive capacity. The present study investigated the relation between subjective ratings of the effort involved in listening to speech in noise, speech recognition performance, and individual working memory (WM) capacity in hearing impaired hearing aid users. In two experiments, participants with hearing loss rated perceived effort during aided speech perception in noise. Noise type and SNR were manipulated in both experiments, and in the second experiment hearing aid compression release settings were also manipulated. Speech recognition performance was measured along with WM capacity. There were 46 participants in all with bilateral mild to moderate sloping hearing loss. In Experiment 1 there were 16 native Danish speakers (eight women and eight men) with a mean age of 63.5 yr (SD = 12.1) and average pure tone (PT) threshold of 47. 6 dB (SD = 9.8). In Experiment 2 there were 30 native Swedish speakers (19 women and 11 men) with a mean age of 70 yr (SD = 7.8) and average PT threshold of 45.8 dB (SD = 6.6). A visual analog scale (VAS) was used for effort rating in both experiments. In Experiment 1, effort was rated at individually adapted SNRs while in Experiment 2 it was rated at fixed SNRs. Speech recognition in noise performance was measured using adaptive procedures in both experiments with Dantale II sentences in Experiment 1 and Hagerman sentences in Experiment 2. WM capacity was measured using a letter-monitoring task in Experiment 1 and the reading span task in Experiment 2. In both experiments, there was a strong and significant relation between rated effort and SNR that was independent of individual WM capacity, whereas the relation between rated effort and noise type seemed to be influenced by individual WM capacity. Experiment 2 showed that hearing aid compression setting influenced rated effort. Subjective ratings of the effort involved in speech recognition in noise reflect SNRs, and individual cognitive capacity seems to influence relative rating of noise type. American Academy of Audiology.

Photoemission Experiments for Charge Characteristics of Individual Dust Grains

NASA Technical Reports Server (NTRS)

Abbas, M. M.; Craven, P. D.; Spann, J. F.; West, E.; Pratico, J.; Tankosic, D.; Venturini, C. C.; Six, N. Frank (Technical Monitor)

2001-01-01

Photoemission experiments with UV radiation have been performed to investigate the microphysics and charge characteristics of individual isolated dust grains of various compositions and sizes by using the electrodynamic balance facility at NASA Marshall Space Flight Center. Dust particles of 2-10 gm diameter are levitated in a vacuum chamber at pressures approximately 10(exp-5) torr and exposed to a collimated beam of UV radiation in the 120-200 nm spectral range from a deuterium lamp source with a MgF2 window. A monochromator is used to select the UV wavelength with a spectral resolution of 8 nm. The electrodynamic facility permits measurements of the charge and diameters of particles of known composition, and monitoring of photoemission rates with the incident UV radiation. Experiments have been conducted on test particles of silica and polystyrene to determine the photoelectric yields and surface equilibrium potentials when exposed to UV radiation. A brief description of an experimental procedure for photoemission studies is given and some preliminary laboratory measurements of the photoelectric yields of individual dust particles are presented.

Comprehensive monitoring for heterogeneous geographically distributed storage

DOE PAGES

Ratnikova, Natalia; Karavakis, E.; Lammel, S.; ...

2015-12-23

Storage capacity at CMS Tier-1 and Tier-2 sites reached over 100 Petabytes in 2014, and will be substantially increased during Run 2 data taking. The allocation of storage for the individual users analysis data, which is not accounted as a centrally managed storage space, will be increased to up to 40%. For comprehensive tracking and monitoring of the storage utilization across all participating sites, CMS developed a space monitoring system, which provides a central view of the geographically dispersed heterogeneous storage systems. The first prototype was deployed at pilot sites in summer 2014, and has been substantially reworked since then.more » In this study, we discuss the functionality and our experience of system deployment and operation on the full CMS scale.« less

Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health.

PubMed

Zhang, William B; Sinha, Drew B; Pittman, William E; Hvatum, Erik; Stroustrup, Nicholas; Pincus, Zachary

2016-10-26

Although many genetic factors and lifestyle interventions are known to affect the mean lifespan of animal populations, the physiological variation displayed by individuals across their lifespans remains largely uncharacterized. Here, we use a custom culture apparatus to continuously monitor five aspects of aging physiology across hundreds of isolated Caenorhabditis elegans individuals kept in a constant environment from hatching until death. Aggregating these measurements into an overall estimate of senescence, we find two chief differences between longer- and shorter-lived individuals. First, though long- and short-lived individuals are physiologically equivalent in early adulthood, longer-lived individuals experience a lower rate of physiological decline throughout life. Second, and counter-intuitively, long-lived individuals have a disproportionately extended "twilight" period of low physiological function. While longer-lived individuals experience more overall days of good health, their proportion of good to bad health, and thus their average quality of life, is systematically lower than that of shorter-lived individuals. We conclude that, within a homogeneous population reared under constant conditions, the period of early-life good health is comparatively uniform, and the most plastic period in the aging process is end-of-life senescence. Copyright © 2016 Elsevier Inc. All rights reserved.

Enhance wound healing monitoring through a thermal imaging based smartphone app

NASA Astrophysics Data System (ADS)

Yi, Steven; Lu, Minta; Yee, Adam; Harmon, John; Meng, Frank; Hinduja, Saurabh

2018-03-01

In this paper, we present a thermal imaging based app to augment traditional appearance based wound growth monitoring. Accurate diagnose and track of wound healing enables physicians to effectively assess, document, and individualize the treatment plan given to each wound patient. Currently, wounds are primarily examined by physicians through visual appearance and wound area. However, visual information alone cannot present a complete picture on a wound's condition. In this paper, we use a smartphone attached thermal imager and evaluate its effectiveness on augmenting visual appearance based wound diagnosis. Instead of only monitoring wound temperature changes on a wound, our app presents physicians a comprehensive measurements including relative temperature, wound healing thermal index, and wound blood flow. Through the rat wound experiments and by monitoring the integrated thermal measurements over 3 weeks of time frame, our app is able to show the underlying healing process through the blood flow. The implied significance of our app design and experiment includes: (a) It is possible to use a low cost smartphone attached thermal imager for added value on wound assessment, tracking, and treatment; and (b) Thermal mobile app can be used for remote wound healing assessment for mobile health based solution.

Using the RPE-Talk Scale to Individualize Physical Activity for Students

ERIC Educational Resources Information Center

Nye, Susan B.; Todd, M. Kent

2013-01-01

For some students, self-selecting a pace during exercise may not provide enough of a physical challenge. Others push themselves so hard that they tire out before they can experience the benefits of exercise. In order to improve self-monitoring of exercise intensity, a variety of tools using the perception of effort and the ability to talk while…

"You Don't Have to Be Black Skinned to Be Black": Indigenous Young People's Bodily Practices

ERIC Educational Resources Information Center

Nelson, Alison

2012-01-01

In contemporary Western societies, disciplinary and normalising technologies function to create a sense of moral obligation within each individual to monitor and regulate the body in terms of health, including diet and exercise. The settler/Aboriginal experience in Australia provides an example of the ways in which biopolitics has operated at a…

Reflective oxygen saturation monitoring at hypothenar and its validation by human hypoxia experiment.

PubMed

Guo, Tao; Cao, Zhengtao; Zhang, Zhengbo; Li, Deyu; Yu, Mengsun

2015-08-05

Pulse oxygen saturation (SpO2) is an important parameter for healthcare, and wearable sensors and systems for SpO2 monitoring have become increasingly popular. The aim of this paper is to develop a novel SpO2 monitoring system, which detects photoplethysmographic (PPG) signals at hypothenar with a reflection-mode sensor embedded into a glove. A special photo-detector section was designed with two photodiodes arranged symmetrically to the red and infrared light-emitting diodes (LED) to enhance the signal quality. The reflective sensor was placed in a soft silicon substrate sewn in a glove to fit the surface of the hypothenar. To lower the power consumption, the LED driving current was reduced and energy-efficient electronic components were applied. The performance for PPG signal detection and SpO2 monitoring was evaluated by human hypoxia experiments. Accelerometer-based adaptive noise cancellation (ANC) methods applying the least mean squares (LMS) and recursive least squares (RLS) algorithms were studied to suppress motion artifact. A total of 20 subjects participated in the hypoxia experiment. The degree of comfort for wearing this system was accepted by them. The PPG signals were detected effectively at SpO2 levels from about 100-70%. The experiment validated the accuracy of the system was 2.34%, compared to the invasive measurements. Both the LMS and RLS algorithms improved the performance during motion. The total current consumed by the system was only 8 mA. It is feasible to detect PPG signal and monitor SpO2 at the location of hypothenar. This novel system can achieve reliable SpO2 measurements at different SpO2 levels and on different individuals. The system is light-weighted, easy to wear and power-saving. It has the potential to be a solution for wearable monitoring, although more work should be conducted to improve the motion-resistant performance significantly.

A novel concentration and viability detection method for Brettanomyces using the Cellometer image cytometry.

PubMed

Martyniak, Brian; Bolton, Jason; Kuksin, Dmitry; Shahin, Suzanne M; Chan, Leo Li-Ying

2017-01-01

Brettanomyces spp. can present unique cell morphologies comprised of excessive pseudohyphae and budding, leading to difficulties in enumerating cells. The current cell counting methods include manual counting of methylene blue-stained yeasts or measuring optical densities using a spectrophotometer. However, manual counting can be time-consuming and has high operator-dependent variations due to subjectivity. Optical density measurement can also introduce uncertainties where instead of individual cells counted, an average of a cell population is measured. In contrast, by utilizing the fluorescence capability of an image cytometer to detect acridine orange and propidium iodide viability dyes, individual cell nuclei can be counted directly in the pseudohyphae chains, which can improve the accuracy and efficiency of cell counting, as well as eliminating the subjectivity from manual counting. In this work, two experiments were performed to demonstrate the capability of Cellometer image cytometer to monitor Brettanomyces concentrations, viabilities, and budding/pseudohyphae percentages. First, a yeast propagation experiment was conducted to optimize software counting parameters for monitoring the growth of Brettanomyces clausenii, Brettanomyces bruxellensis, and Brettanomyces lambicus, which showed increasing cell concentrations, and varying pseudohyphae percentages. The pseudohyphae formed during propagation were counted either as multiple nuclei or a single multi-nuclei organism, where the results of counting the yeast as a single multi-nuclei organism were directly compared to manual counting. Second, a yeast fermentation experiment was conducted to demonstrate that the proposed image cytometric analysis method can monitor the growth pattern of B. lambicus and B. clausenii during beer fermentation. The results from both experiments displayed different growth patterns, viability, and budding/pseudohyphae percentages for each Brettanomyces species. The proposed Cellometer image cytometry method can improve efficiency and eliminate operator-dependent variations of cell counting compared with the traditional methods, which can potentially improve the quality of beverage products employing Brettanomyces yeasts.

H-GRASP: the feasibility of an upper limb home exercise program monitored by phone for individuals post stroke

PubMed Central

Simpson, Lisa A.; Eng, Janice J.; Chan, May

2017-01-01

Abstract Purpose: To investigate the feasibility of a phone-monitored home exercise program for the upper limb following stroke. Methods: A pre-post double baseline repeated measures design was used. Participants completed an 8-week home exercise program that included behavioural strategies to promote greater use of the affected upper limb. Participants were monitored weekly by therapists over the phone. The following feasibility outcomes were collected: Process (e.g. recruitment rate); Resources (e.g. exercise adherence rate); Management (e.g. therapist monitoring) and Scientific (e.g. safety, effect sizes). Clinical outcomes included: The Chedoke Arm and Hand Inventory, Motor Activity Log, grip strength and the Canadian Occupational Performance Measure. Results: Eight individuals with stroke were recruited and six participants completed the exercise program. All but one of the six participants met the exercise target of 60 minutes/day, 6 days/week. Participants were stable across the baseline period. The following post-treatment effect sizes were observed: CAHAI (0.944, p = 0.046); MALQ (0.789, p = 0.03) grip strength (0.947, p = 0.046); COPM (0.789, p = 0.03). Improvements were maintained at three and six month follow ups. Conclusions: Community dwelling individuals with stroke may benefit from a phone-monitored upper limb home exercise program that includes behavioural strategies that promote transfer of exercise gains into daily upper limb use.Implications for RehabilitationA repetitive, task-oriented home exercise program that utilizes telephone supervision may be an effective method for the treatment of the upper limb following strokeThis program is best suited for individuals with mild to moderate level impairment and experience a sufficient level of challenge from the exercisesAn exercise program that includes behavioural strategies may promote transfer of exercise gains into greater use of the affected upper limb during daily activities PMID:27017890

Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel.

PubMed

Sato, Kei A; Hachiya, Tsuyoshi; Iwaya, Takeshi; Kume, Kohei; Matsuo, Teppei; Kawasaki, Keisuke; Abiko, Yukito; Akasaka, Risaburo; Matsumoto, Takayuki; Otsuka, Koki; Nishizuka, Satoshi S

2016-01-01

Circulating tumor DNA (ctDNA) carries information on tumor burden. However, the mutation spectrum is different among tumors. This study was designed to examine the utility of ctDNA for monitoring tumor burden based on an individual mutation profile. DNA was extracted from a total of 176 samples, including pre- and post-operational plasma, primary tumors, and peripheral blood mononuclear cells (PBMC), from 44 individuals with colorectal tumor who underwent curative resection of colorectal tumors, as well as nine healthy individuals. Using a panel of 50 cancer-associated genes, tumor-unique mutations were identified by comparing the single nucleotide variants (SNVs) from tumors and PBMCs with an Ion PGM sequencer. A group of the tumor-unique mutations from individual tumors were designated as individual marker mutations (MMs) to trace tumor burden by ctDNA using droplet digital PCR (ddPCR). From these experiments, three major objectives were assessed: (a) Tumor-unique mutations; (b) mutation spectrum of a tumor; and (c) changes in allele frequency of the MMs in ctDNA after curative resection of the tumor. A total of 128 gene point mutations were identified in 27 colorectal tumors. Twenty-six genes were mutated in at least 1 sample, while 14 genes were found to be mutated in only 1 sample, respectively. An average of 2.7 genes were mutated per tumor. Subsequently, 24 MMs were selected from SNVs for tumor burden monitoring. Among the MMs found by ddPCR with > 0.1% variant allele frequency in plasma DNA, 100% (8 out of 8) exhibited a decrease in post-operation ctDNA, whereas none of the 16 MMs found by ddPCR with < 0.1% variant allele frequency in plasma DNA showed a decrease. This panel of 50 cancer-associated genes appeared to be sufficient to identify individual, tumor-unique, mutated ctDNA markers in cancer patients. The MMs showed the clinical utility in monitoring curatively-treated colorectal tumor burden if the allele frequency of MMs in plasma DNA is above 0.1%.

Integrating Social Media and Mobile Sensor Data for Clinical Decision Support: Concept and Requirements.

PubMed

Denecke, Kerstin

2016-01-01

Social media are increasingly used by individuals for the purpose of collecting data and reporting on the personal health status, on health issues, symptoms and experiences with treatments. Beyond, fitness trackers are more used by individuals to monitor their fitness and health. The health data that is becoming available due to these developments could provide a valuable source for continuous health monitoring, prevention of unexpected health events and clinical decision making since it gives insights into behavior and life habits. However, an integration of the data is challenging. This paper aims triggering the discussion about this current topic. We present a concept for integrating social media data with mobile sensor data and clinical data using digital patient modelling. Further, we collect requirements and challenges for a possible realization of the concept. Challenges include the data volume, reliability and semantic interoperability.

Sensing interstitial glucose to nudge active lifestyles (SIGNAL): feasibility of combining novel self-monitoring technologies for persuasive behaviour change

PubMed Central

Kingsnorth, Andrew P; Orme, Mark W; Sherar, Lauren B; Esliger, Dale W

2017-01-01

Introduction Increasing physical activity (PA) reduces the risk of developing diabetes, highlighting the role of preventive medicine approaches. Changing lifestyle behaviours is difficult and is often predicated on the assumption that individuals are willing to change their lifestyles today to reduce the risk of developing disease years or even decades later. The self-monitoring technologies tested in this study will present PA feedback in real time, parallel with acute physiological data. Presenting the immediate health benefits of being more physically active may help enact change by observing the immediate consequences of that behaviour. The present study aims to assess user engagement with the self-monitoring technologies in individuals at moderate-to-high risk of developing type 2 diabetes. Methods and analysis 45 individuals with a moderate-to-high risk, aged ≥40 years old and using a compatible smartphone, will be invited to take part in a 7-week protocol. Following 1 week of baseline measurements, participants will be randomised into one of three groups: group 1— glucose feedback followed by biobehavioural feedback (glucose plus PA); group 2—PA feedback followed by biobehavioural feedback; group 3—biobehavioural feedback. A PA monitor and a flash glucose monitor will be deployed during the intervention. Participants will wear both devices throughout the intervention but blinded to feedback depending on group allocation. The primary outcome is the level of participant engagement and will be assessed by device use and smartphone usage. Feasibility will be assessed by the practicality of the technology and screening for diabetes risk. Semistructured interviews will be conducted to explore participant experiences using the technologies. Trial registration number ISRCTN17545949. Registered on 15/05/2017. PMID:28993396

Concurrent measurement of "real-world" stress and arousal in individuals with psychosis: assessing the feasibility and validity of a novel methodology.

PubMed

Kimhy, David; Delespaul, Philippe; Ahn, Hongshik; Cai, Shengnan; Shikhman, Marina; Lieberman, Jeffrey A; Malaspina, Dolores; Sloan, Richard P

2010-11-01

Psychosis has been repeatedly suggested to be affected by increases in stress and arousal. However, there is a dearth of evidence supporting the temporal link between stress, arousal, and psychosis during "real-world" functioning. This paucity of evidence may stem from limitations of current research methodologies. Our aim is to the test the feasibility and validity of a novel methodology designed to measure concurrent stress and arousal in individuals with psychosis during "real-world" daily functioning. Twenty patients with psychosis completed a 36-hour ambulatory assessment of stress and arousal. We used experience sampling method with palm computers to assess stress (10 times per day, 10 AM → 10 PM) along with concurrent ambulatory measurement of cardiac autonomic regulation using a Holter monitor. The clocks of the palm computer and Holter monitor were synchronized, allowing the temporal linking of the stress and arousal data. We used power spectral analysis to determine the parasympathetic contributions to autonomic regulation and sympathovagal balance during 5 minutes before and after each experience sample. Patients completed 79% of the experience samples (75% with a valid concurrent arousal data). Momentary increases in stress had inverse correlation with concurrent parasympathetic activity (ρ = -.27, P < .0001) and positive correlation with sympathovagal balance (ρ = .19, P = .0008). Stress and heart rate were not significantly related (ρ = -.05, P = .3875). The findings support the feasibility and validity of our methodology in individuals with psychosis. The methodology offers a novel way to study in high time resolution the concurrent, "real-world" interactions between stress, arousal, and psychosis. The authors discuss the methodology's potential applications and future research directions.

A method for environmental acoustic analysis improvement based on individual evaluation of common sources in urban areas.

PubMed

López-Pacheco, María G; Sánchez-Fernández, Luis P; Molina-Lozano, Herón

2014-01-15

Noise levels of common sources such as vehicles, whistles, sirens, car horns and crowd sounds are mixed in urban soundscapes. Nowadays, environmental acoustic analysis is performed based on mixture signals recorded by monitoring systems. These mixed signals make it difficult for individual analysis which is useful in taking actions to reduce and control environmental noise. This paper aims at separating, individually, the noise source from recorded mixtures in order to evaluate the noise level of each estimated source. A method based on blind deconvolution and blind source separation in the wavelet domain is proposed. This approach provides a basis to improve results obtained in monitoring and analysis of common noise sources in urban areas. The method validation is through experiments based on knowledge of the predominant noise sources in urban soundscapes. Actual recordings of common noise sources are used to acquire mixture signals using a microphone array in semi-controlled environments. The developed method has demonstrated great performance improvements in identification, analysis and evaluation of common urban sources. © 2013 Elsevier B.V. All rights reserved.

Database and interactive monitoring system for the photonics and electronics of RPC Muon Trigger in CMS experiment

NASA Astrophysics Data System (ADS)

Wiacek, Daniel; Kudla, Ignacy M.; Pozniak, Krzysztof T.; Bunkowski, Karol

2005-02-01

The main task of the RPC (Resistive Plate Chamber) Muon Trigger monitoring system design for the CMS (Compact Muon Solenoid) experiment (at LHC in CERN Geneva) is the visualization of data that includes the structure of electronic trigger system (e.g. geometry and imagery), the way of its processes and to generate automatically files with VHDL source code used for programming of the FPGA matrix. In the near future, the system will enable the analysis of condition, operation and efficiency of individual Muon Trigger elements, registration of information about some Muon Trigger devices and present previously obtained results in interactive presentation layer. A broad variety of different database and programming concepts for design of Muon Trigger monitoring system was presented in this article. The structure and architecture of the system and its principle of operation were described. One of ideas for building this system is use object-oriented programming and design techniques to describe real electronics systems through abstract object models stored in database and implement these models in Java language.

Unobtrusive measurement of indoor energy expenditure using an infrared sensor-based activity monitoring system.

PubMed

Hwang, Bosun; Han, Jonghee; Choi, Jong Min; Park, Kwang Suk

2008-11-01

The purpose of this study was to develop an unobtrusive energy expenditure (EE) measurement system using an infrared (IR) sensor-based activity monitoring system to measure indoor activities and to estimate individual quantitative EE. IR-sensor activation counts were measured with a Bluetooth-based monitoring system and the standard EE was calculated using an established regression equation. Ten male subjects participated in the experiment and three different EE measurement systems (gas analyzer, accelerometer, IR sensor) were used simultaneously in order to determine the regression equation and evaluate the performance. As a standard measurement, oxygen consumption was simultaneously measured by a portable metabolic system (Metamax 3X, Cortex, Germany). A single room experiment was performed to develop a regression model of the standard EE measurement from the proposed IR sensor-based measurement system. In addition, correlation and regression analyses were done to compare the performance of the IR system with that of the Actigraph system. We determined that our proposed IR-based EE measurement system shows a similar correlation to the Actigraph system with the standard measurement system.

Proof-of-Principle Dermal Decontamination Experiments: Swine Skin

DTIC Science & Technology

2007-04-01

approvals it was decided to first demonstrate the proof-of-principle of dermal decontamination for this model using swine skin samples ex vivo . When...appropriate individual protection equipment (IPE) and dosimetry . 3. All activities were monitored by the DRDC Ottawa RadSO. 4. The workstation...while working with the radionuclides, as well as the necessary dosimetry . All personnel wore standard Health Canada issued thermo- luminescent

From Insurgency to Stability. Volume 1: Key Capabilities and Practices

DTIC Science & Technology

2011-01-01

newly arrived personnel to understand the status of ongoing projects and whether individual contractors are performing to the contract...identifying where project funds are expended wastefully and where performance is substandard). That said, while an improved system to monitor...been disappoint- ing. Experiences there have shown that “capacity - building ” in the jus- tice sector does not necessarily produce better performance

An assessment of domain-general metacognitive responding in rhesus monkeys.

PubMed

Brown, Emily Kathryn; Templer, Victoria L; Hampton, Robert R

2017-02-01

Metacognition is the ability to monitor and control one's cognition. Monitoring may involve either public cues or introspection of private cognitive states. We tested rhesus monkeys (Macaca mulatta) in a series of generalization tests to determine which type of cues control metacognition. In Experiment 1, monkeys learned a perceptual discrimination in which a "decline-test" response allowed them to avoid tests and receive a guaranteed small reward. Monkeys declined more difficult than easy tests. In Experiments 2-4, we evaluated whether monkeys generalized this metacognitive responding to new perceptual tests. Monkeys showed a trend toward generalization in Experiments 2 & 3, and reliable generalization in Experiment 4. In Experiments 5 & 6, we presented the decline-test response in a delayed matching-to-sample task. Memory tests differed from perceptual tests in that the appearance of the test display could not control metacognitive responding. In Experiment 6, monkeys made prospective metamemory judgments before seeing the tests. Generalization across perceptual tests with different visual properties and mixed generalization from perceptual to memory tests provide provisional evidence that domain-general, private cues controlled metacognition in some monkeys. We observed individual differences in generalization, suggesting that monkeys differ in use of public and private metacognitive cues. Copyright © 2016 Elsevier B.V. All rights reserved.

Making and monitoring errors based on altered auditory feedback

PubMed Central

Pfordresher, Peter Q.; Beasley, Robertson T. E.

2014-01-01

Previous research has demonstrated that altered auditory feedback (AAF) disrupts music performance and causes disruptions in both action planning and the perception of feedback events. It has been proposed that this disruption occurs because of interference within a shared representation for perception and action (Pfordresher, 2006). Studies reported here address this claim from the standpoint of error monitoring. In Experiment 1 participants performed short melodies on a keyboard while hearing no auditory feedback, normal auditory feedback, or alterations to feedback pitch on some subset of events. Participants overestimated error frequency when AAF was present but not for normal feedback. Experiment 2 introduced a concurrent load task to determine whether error monitoring requires executive resources. Although the concurrent task enhanced the effect of AAF, it did not alter participants’ tendency to overestimate errors when AAF was present. A third correlational study addressed whether effects of AAF are reduced for a subset of the population who may lack the kind of perception/action associations that lead to AAF disruption: poor-pitch singers. Effects of manipulations similar to those presented in Experiments 1 and 2 were reduced for these individuals. We propose that these results are consistent with the notion that AAF interference is based on associations between perception and action within a forward internal model of auditory-motor relationships. PMID:25191294

High-throughput crystallization screening.

PubMed

Skarina, Tatiana; Xu, Xiaohui; Evdokimova, Elena; Savchenko, Alexei

2014-01-01

Protein structure determination by X-ray crystallography is dependent on obtaining a single protein crystal suitable for diffraction data collection. Due to this requirement, protein crystallization represents a key step in protein structure determination. The conditions for protein crystallization have to be determined empirically for each protein, making this step also a bottleneck in the structure determination process. Typical protein crystallization practice involves parallel setup and monitoring of a considerable number of individual protein crystallization experiments (also called crystallization trials). In these trials the aliquots of purified protein are mixed with a range of solutions composed of a precipitating agent, buffer, and sometimes an additive that have been previously successful in prompting protein crystallization. The individual chemical conditions in which a particular protein shows signs of crystallization are used as a starting point for further crystallization experiments. The goal is optimizing the formation of individual protein crystals of sufficient size and quality to make them suitable for diffraction data collection. Thus the composition of the primary crystallization screen is critical for successful crystallization.Systematic analysis of crystallization experiments carried out on several hundred proteins as part of large-scale structural genomics efforts allowed the optimization of the protein crystallization protocol and identification of a minimal set of 96 crystallization solutions (the "TRAP" screen) that, in our experience, led to crystallization of the maximum number of proteins.

NUCLA Circulating Atmospheric Fluidized Bed Demonstration Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keith, Raymond E.; Heller, Thomas J.; Bush, Stuart A.

1991-01-01

This Annual Report on Colorado-Ute Electric Association's NUCLA Circulating Fluidized Bed (CFB) Demonstration Program covers the period from February 1987 through December 1988. The outline for presentation in this report includes a summary of unit operations along with individual sections covering progress in study plan areas that commenced during this reporting period. These include cold-mode shakedown and calibration, plant commercial performance statistics, unit start-up (cold), coal and limestone preparation and handling, ash handling system performance and operating experience, tubular air heater, baghouse operation and performance, materials monitoring, and reliability monitoring. During this reporting period, the coal-mode shakedown and calibration planmore » was completed. (VC)« less

Looking inward and back: Real-time monitoring of visual working memories.

PubMed

Suchow, Jordan W; Fougnie, Daryl; Alvarez, George A

2017-04-01

Confidence in our memories is influenced by many factors, including beliefs about the perceptibility or memorability of certain kinds of objects and events, as well as knowledge about our skill sets, habits, and experiences. Notoriously, our knowledge and beliefs about memory can lead us astray, causing us to be overly confident in eyewitness testimony or to overestimate the frequency of recent experiences. Here, using visual working memory as a case study, we stripped away all these potentially misleading cues, requiring observers to make confidence judgments by directly assessing the quality of their memory representations. We show that individuals can monitor the status of information in working memory as it degrades over time. Our findings suggest that people have access to information reflecting the existence and quality of their working memories, and furthermore, that they can use this information to guide their behavior. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Sedation provider practice variation: a survey analysis of pediatric emergency subspecialists and fellows.

PubMed

Shavit, Itai; Leder, Marc; Cohen, Daniel M

2010-10-01

Pediatric emergency physicians use various techniques and medications when performing procedural sedation and analgesia. The goals of our study were to assess US pediatric emergency medicine subspecialists and fellows (PEMSSFs) for individual practice variation and to evaluate (1) the use of supplemental oxygen and capnography monitoring and (2) adverse sedation events (ADSEs). A Web-based tool was used to survey and analyze data collected from a selected group of PEMSSFs, regarding their responses to 5 common sedation case scenarios, use of supplemental oxygen and capnography monitoring, and ADSEs. Logistic regression analysis was used to examine the association between medication strategy and various levels of professional experience. Two hundred one surveys were received. One hundred ninety-five of these were eligible for the study: 140 from specialists and 55 from fellows. Respondents used multiple combinations of pharmaceutical agents to the scenarios presented. For some scenarios, statistical association was found between medication selection strategy and longer professional experience. Sixty percent of respondents do not routinely provide oxygen supplementation. Despite current guidelines supporting the routine use of capnography monitoring, 45% of respondents never use it. Adverse sedation event was reported in 17 cases; all patients were discharged with no further complications. A statistical association was found between years of practitioner experience and the likelihood of reporting an ADSE (P < 0.018). This group of PEMSSFs reported a wide spectrum of medication sedation strategies, dichotomous approaches to the use of oxygen supplementation and capnography monitoring, and a low rate of ADSEs.

Dynamic Analyses of Result Quality in Energy-Aware Approximate Programs

NASA Astrophysics Data System (ADS)

RIngenburg, Michael F.

Energy efficiency is a key concern in the design of modern computer systems. One promising approach to energy-efficient computation, approximate computing, trades off output precision for energy efficiency. However, this tradeoff can have unexpected effects on computation quality. This thesis presents dynamic analysis tools to study, debug, and monitor the quality and energy efficiency of approximate computations. We propose three styles of tools: prototyping tools that allow developers to experiment with approximation in their applications, online tools that instrument code to determine the key sources of error, and online tools that monitor the quality of deployed applications in real time. Our prototyping tool is based on an extension to the functional language OCaml. We add approximation constructs to the language, an approximation simulator to the runtime, and profiling and auto-tuning tools for studying and experimenting with energy-quality tradeoffs. We also present two online debugging tools and three online monitoring tools. The first online tool identifies correlations between output quality and the total number of executions of, and errors in, individual approximate operations. The second tracks the number of approximate operations that flow into a particular value. Our online tools comprise three low-cost approaches to dynamic quality monitoring. They are designed to monitor quality in deployed applications without spending more energy than is saved by approximation. Online monitors can be used to perform real time adjustments to energy usage in order to meet specific quality goals. We present prototype implementations of all of these tools and describe their usage with several applications. Our prototyping, profiling, and autotuning tools allow us to experiment with approximation strategies and identify new strategies, our online tools succeed in providing new insights into the effects of approximation on output quality, and our monitors succeed in controlling output quality while still maintaining significant energy efficiency gains.

On-line coupling of a miniaturized bioreactor with capillary electrophoresis, via a membrane interface, for monitoring the production of organic acids by microorganisms.

PubMed

Ehala, S; Vassiljeva, I; Kuldvee, R; Vilu, R; Kaljurand, M

2001-09-01

Capillary electrophoresis (CE) can be a valuable tool for on-line monitoring of bioprocesses. Production of organic acids by phosphorus-solubilizing bacteria and fermentation of UHT milk were monitored and controlled by use of a membrane-interfaced dialysis device and a home-made microsampler for a capillary electrophoresis unit. Use of this specially designed sampling device enabled rapid consecutive injections without interruption of the high voltage. No additional sample preparation was required. The time resolution of monitoring in this particular work was approximately 2 h, but could be reduced to 2 min. Analytes were detected at low microg mL(-1) levels with a reproducibility of approximately 10%. To demonstrate the potential of CE in processes of biotechnological interest, results from monitoring phosphate solubilization by bacteria were submitted to qualitative and quantitative analysis. Fermentation experiments on UHT milk showed that monitoring of the processes by CE can provide good resolution of complex mixtures, although for more specific, detailed characterization the identification of individual substances is needed.

Occupational exposure of electrical utility linemen to pentachlorophenol.

PubMed

Thind, K S; Karmali, S; House, R A

1991-12-01

Occupational exposure to pentachlorophenol (PCP) for a crew of electrical utility linemen was monitored over a 6-month period by using total PCP in urine per gram of creatinine as a biological monitoring parameter. Urine samples were collected from three groups: A, B, and control, at a 4-week frequency during 1989. Group A was required to use new gloves after each 4-week work period; Group B changed gloves on a need basis as per normal operating procedure. The control group consisted of members of the administrative office staff who were not occupationally exposed. The used gloves returned by Group A were monitored for contamination. On the basis of analysis of the collected data the following conclusions were noted. (1) The linemen experienced a seasonal exposure pattern with exposures peaking in July and August. This seasonal effect was also observed with glove contamination data. (2) The glove contamination levels were significantly associated with urine PCP concentrations when both these variables were expressed as geometric means for the individuals in Group A. Inclusion of work experience as an additional variable enhances this association. Less experienced linemen tended to perform more activities with higher current exposure and had higher urine and glove PCP measurements and higher correlations between these variables than more experienced linemen. (3) Over the study period, the difference in long-term exposures of Group A and Group B linemen was not statistically significant. (4) The long-term individual exposures, calculated as the geometric mean of each individual's sequential sample readings, were all below the biological monitoring guideline value of 1000 micrograms PCP/g creatinine.

Standards, documents of relevance and directives in individual monitoring: is European individual monitoring in compliance with standards?

PubMed

Fantuzzi, E

2007-01-01

Individual monitoring services (IMS) in Europe do not comply with the same legal or approval requirements. Anyway, a degree of harmonisation existing in individual monitoring practices in Europe has been achieved mainly thanks to documents as standards or international recommendations, which with different weight represent invaluable vehicles of condensed information transfer. However, implementation of standards is not straightforward and harmonisation is not directly a consequence. Somehow, 'harmony' is needed also in standards: IEC and ISO standards, on performance requirements for dosemeters sometimes have different approaches (i.e. performance criteria). Moreover, standards do not all refer to reliability, and therefore being in compliance with standards does not by itself assure that dose results are reliable. Standards are not the only reference documents for an IMS. EURADOS working group on 'Harmonisation of Individual Monitoring in Europe', who has been active in the years 2001-2004, suggested a classification of publication on individual monitoring, distinguishing between standards and documents of relevance, which can be both national and international. None of the two categories are mandatory unless specified in legislation. The Council Directive 96/29/EURATOM and its implementation in each EU Member States has fostered harmonisation of the approach (i.e. approval of dosimetric services) and of the reference quantities for individual monitoring within EU, but national legislation still allow substantial differences in individual monitoring from country to country.

Obese persons' physical activity experiences and motivations across weight changes: a qualitative exploratory study.

PubMed

Bombak, Andrea E

2015-11-14

Obese individuals are encouraged to participate in physical activity. However, few qualitative studies have explored obese individuals' motivations for and experiences with physical activity. The physical activity experiences of self-identified obese or formerly obese persons (n = 15) were explored through in-depth, semi-structured, audio-taped, repeated interviews and ethnography over one year. Participant observation occurred at multiple sites identified by participants as meaningful to them as obese persons. Data from interview transcripts and fieldnotes were analyzed via thematic content analysis. Underlying goals for engaging in physical activity were diverse. Emergent motivation themes included: protection, pressure, and pleasure. Participants were protective of maintaining functional capacity, establishing fit identities, and achieving weight loss. Participants also discussed feelings of excessive pressure to continue progressing toward weight and fitness goals. Enjoyment in physical activity was often a by-product for all participants and could become a sought-after endpoint. Finding an environment in which participants felt safe, accepted, and encouraged to be active was extremely important for continual engagement. Obese individuals enjoyed physical activity and were concerned about maintaining functional fitness. Stigmatization and untenable goals and monitoring could disrupt physical activity.

Smoking, Drinking, and Drug Use in Young Adulthood: The Impacts of New Freedoms and New Responsibilities. Research Monographs in Adolescence (RMA).

ERIC Educational Resources Information Center

Bachman, Jerald G.; Wadsworth, Katherine N.; O'Malley, Patrick M.; Johnston, Lloyd D.; Schulenberg, John E.

This book focuses on transitions into young adulthood by examining key roles and experiences of young adults and how they relate to changes in drug use. The findings are based on the nationwide Monitoring the Future project, and represent the majority of individuals who entered young adulthood in the United States during the years 1976 through…

Comparison of Heart Rate Response to Tennis Activity between Persons with and without Spinal Cord Injuries: Implications for a Training Threshold

ERIC Educational Resources Information Center

Barfield, J. P.; Malone, Laurie A.; Coleman, Tristica A.

2009-01-01

The purpose of this study was to evaluate the ability of individuals with spinal cord injury (SCI) to reach a training threshold during on-court sport activity. Monitors collected heart rate (HR) data every 5 s for 11 wheelchair tennis players (WCT) with low paraplegia and 11 able-bodied controls matched on experience and skill level (ABT).…

The role of work-related and personal factors in diabetes self-management.

PubMed

Weijman, Iris; Ros, Wynand J G; Rutten, Guy E H M; Schaufeli, Wilmar B; Schabracq, Marc J; Winnubst, Jacques A M

2005-10-01

The aim of this study was to investigate how factors in the workplace and personal factors are related to the frequency with which people with diabetes perform self-management activities and the degree to which they do or do not experience the performing of self-management activities as a burden. Two hundred and ninety-two employees with insulin-treated diabetes completed questionnaires on socio-demographic and illness-related background variables, work experience, diabetes self-efficacy, social support outside of work, coping styles and self-management activities. The results indicate that employees who reported a high workload were more likely to perceive injecting insulin as a burden. The level of social support was positively related to the frequency of dietary self-management in type 2 diabetes and negatively related to the sense of being burdened by dietary self-management in type 1 diabetes. With respect to personal factors, we found that a diabetes avoidance coping style was associated particularly with infrequent blood glucose monitoring and a high sense of being burdened by blood glucose monitoring. Individuals with a low level of self-efficacy were more likely to perceive all types of self-management activities as a burden. These results may guide health professionals when counseling individuals with diabetes.

Lipid monitoring in patients with schizophrenia prescribed second-generation antipsychotics.

PubMed

Weissman, Ellen M; Zhu, Carolyn W; Schooler, Nina R; Goetz, Raymond R; Essock, Susan M

2006-09-01

Treatment with second-generation antipsychotic (SGA) medications has been linked with increased rates of the metabolic syndrome (i.e., dyslipidemia, obesity, and hyperglycemia). Several sets of published recommendations now provide clinicians with guidelines for monitoring metabolic parameters in individuals with schizophrenia treated with SGAs. However, few data are available regarding actual metabolic monitoring practices in this patient population. The objectives of the study were to determine baseline lipid monitoring rates for individuals with schizophrenia prescribed SGAs during the period prior to the publication of monitoring guidelines and to determine whether individuals with abnormal lipid levels received follow-up monitoring sooner than individuals with normal levels. Lipid monitoring rates for 408 individuals with schizophrenia who were prescribed SGAs from October 1999 to October 2003 were examined using administrative data from a Veterans Affairs facility. Survival analysis was used to examine time to follow-up lipid measurement and to compare time to follow-up measure for individuals with normal initial lipid levels versus those with elevated initial lipid levels. Eighty-five percent of individuals had at least 1 measurement for total cholesterol or triglycerides in a 4-year period. Abnormal initial measurements predicted significantly earlier follow-up monitoring (p < .005 for total cholesterol, p < .05 for triglycerides, p < .001 for low-density lipoprotein cholesterol). However, median time to follow-up measure was 304 days (approximately 10 months) for individuals with elevated total cholesterol levels, which is too long for optimal clinical follow-up. Program managers and clinicians should assess adequacy of monitoring and support quality improvement initiatives in this area.

Estimation of peacock bass (Cichla spp.) mortality rate during catch-release fishing employing different post-capture procedures.

PubMed

Barroco, L S A; Freitas, C E C; Lima, Á C

2018-05-01

The effect of catch-and-release fishing on the survival of peacock bass (Cichla spp.) was evaluated by comparing two types of artificial bait (jig and shallow-diver plugs) and two types of post-catch confinement. Two experiments were conducted during the periods January-February and October-November 2012 in the Unini River, a right-bank tributary of the Negro River. In total, 191 peacock bass were captured. Both groups of fish were subjected to experimental confinement (collective and individual) for three days. Additionally, 11 fish were tagged with radio transmitters for telemetry monitoring. Mortality rate was estimated as the percentage of dead individuals for each type of bait and confinement. For peacock bass caught with jig baits, mortality was zero. The corresponding figure for shallow-diver bait was 1.66% for fish in collective containment, 18.18% for fish monitored by telemetry and 0% for individuals confined individually. Our results show low post-release mortality rates for peacock bass. Furthermore, neither the type of confinement nor the type of bait had a statistically significant influence on mortality rates. While future studies could include other factors in the analysis, our results show that catch-and-release fishing results in low mortality rates.

Transmission Bearing Damage Detection Using Decision Fusion Analysis

NASA Technical Reports Server (NTRS)

Dempsey, Paula J.; Lewicki, David G.; Decker, Harry J.

2004-01-01

A diagnostic tool was developed for detecting fatigue damage to rolling element bearings in an OH-58 main rotor transmission. Two different monitoring technologies, oil debris analysis and vibration, were integrated using data fusion into a health monitoring system for detecting bearing surface fatigue pitting damage. This integrated system showed improved detection and decision-making capabilities as compared to using individual monitoring technologies. This diagnostic tool was evaluated by collecting vibration and oil debris data from tests performed in the NASA Glenn 500 hp Helicopter Transmission Test Stand. Data was collected during experiments performed in this test rig when two unanticipated bearing failures occurred. Results show that combining the vibration and oil debris measurement technologies improves the detection of pitting damage on spiral bevel gears duplex ball bearings and spiral bevel pinion triplex ball bearings in a main rotor transmission.

Project management web tools at the MICE experiment

NASA Astrophysics Data System (ADS)

Coney, L. R.; Tunnell, C. D.

2012-12-01

Project management tools like Trac are commonly used within the open-source community to coordinate projects. The Muon Ionization Cooling Experiment (MICE) uses the project management web application Redmine to host mice.rl.ac.uk. Many groups within the experiment have a Redmine project: analysis, computing and software (including offline, online, controls and monitoring, and database subgroups), executive board, and operations. All of these groups use the website to communicate, track effort, develop schedules, and maintain documentation. The issue tracker is a rich tool that is used to identify tasks and monitor progress within groups on timescales ranging from immediate and unexpected problems to milestones that cover the life of the experiment. It allows the prioritization of tasks according to time-sensitivity, while providing a searchable record of work that has been done. This record of work can be used to measure both individual and overall group activity, identify areas lacking sufficient personnel or effort, and as a measure of progress against the schedule. Given that MICE, like many particle physics experiments, is an international community, such a system is required to allow easy communication within a global collaboration. Unlike systems that are purely wiki-based, the structure of a project management tool like Redmine allows information to be maintained in a more structured and logical fashion.

Predictors of nurses' experience of verbal abuse by nurse colleagues.

PubMed

Keller, Ronald; Krainovich-Miller, Barbara; Budin, Wendy; Djukic, Maja

Between 45% and 94% of registered nurses (RNs) experience verbal abuse, which is associated with physical and psychological harm. Although several studies examined predictors of RNs' verbal abuse, none examined predictors of RNs' experiences of verbal abuse by RN colleagues. To examine individual, workplace, dispositional, contextual, and interpersonal predictors of RNs' reported experiences of verbal abuse from RN colleagues. In this secondary analysis, a cross-sectional design with multiple linear regression analysis was used to examine the effect of 23 predictors on verbal abuse by RN colleagues in a sample of 1,208 early career RNs. Selected variables in the empirical intragroup conflict model explained 23.8% of variance in RNs' experiences of verbal abuse by RN colleagues. A number of previously unstudied factors were identified that organizational leaders can monitor and develop or modify policies to prevent early career RNs' experiences of verbal abuse by RN colleagues. Copyright © 2017 Elsevier Inc. All rights reserved.

Persuasive performance feedback: the effect of framing on self-efficacy.

PubMed

Choe, Eun Kyoung; Lee, Bongshin; Munson, Sean; Pratt, Wanda; Kientz, Julie A

2013-01-01

Self-monitoring technologies have proliferated in recent years as they offer excellent potential for promoting healthy behaviors. Although these technologies have varied ways of providing real-time feedback on a user's current progress, we have a dearth of knowledge of the framing effects on the performance feedback these tools provide. With an aim to create influential, persuasive performance feedback that will nudge people toward healthy behaviors, we conducted an online experiment to investigate the effect of framing on an individual's self-efficacy. We identified 3 different types of framing that can be applicable in presenting performance feedback: (1) the valence of performance (remaining vs. achieved framing), (2) presentation type (text-only vs. text with visual), and (3) data unit (raw vs. percentage). Results show that the achieved framing could lead to an increased perception of individual's performance capabilities. This work provides empirical guidance for creating persuasive performance feedback, thereby helping people designing self-monitoring technologies to promote healthy behaviors.

Telemonitoring and/or self-monitoring of blood pressure in hypertension (TASMINH4): protocol for a randomised controlled trial.

PubMed

Franssen, Marloes; Farmer, Andrew; Grant, Sabrina; Greenfield, Sheila; Heneghan, Carl; Hobbs, Richard; Hodgkinson, James; Jowett, Susan; Mant, Jonathan; Martin, Una; Milner, Siobhan; Monahan, Mark; Ogburn, Emma; Perera-Salazar, Rafael; Schwartz, Claire; Yu, Ly-Mee; McManus, Richard J

2017-02-13

Self-monitoring of hypertension is associated with lower systolic blood pressure (SBP). However, evidence for the use of self-monitoring to titrate antihypertensive medication by physicians is equivocal. Furthermore, there is some evidence for the efficacy of telemonitoring in the management of hypertension but it is not clear what this adds over and above self-monitoring. This trial aims to evaluate whether GP led antihypertensive titration using self-monitoring results in lower SBP compared to usual care and whether telemonitoring adds anything to self-monitoring alone. This will be a pragmatic primary care based, unblinded, randomised controlled trial of self-monitoring of BP with or without telemonitoring compared to usual care. Eligible patients will have poorly controlled hypertension (>140/90 mmHg) and will be recruited from primary care. Participants will be individually randomised to either usual care, self-monitoring alone, or self-monitoring with telemonitoring. The primary outcome of the trial will be difference in clinic SBP between intervention and control groups at 12 months adjusted for baseline SBP, gender, BP target and practice. At least 1110 patients will be sufficient to detect a difference in SBP between self-monitoring with or without telemonitoring and usual care of 5 mmHg with 90% power with an adjusted alpha of 0.017 (2-sided) to adjust for all three pairwise comparisons. Other outcomes will include adherence of anti-hypertensive medication, lifestyle behaviours, health-related quality of life, and adverse events. An economic analysis will consider both within trial costs and a model extrapolating the results thereafter. A qualitative sub study will gain insights into the views, experiences and decision making processes of patients and health care professionals focusing on the acceptability of self-monitoring and telemonitoring in the routine management of hypertension. The results of the trial will be directly applicable to primary care in the UK. If successful, self-monitoring of BP in people with hypertension would be applicable to hundreds of thousands of individuals in the UK. ISRCTN 83571366 . Registered 17 July 2014.

Patients’ and clinicians’ views on the optimum schedules for self-monitoring of blood pressure: a qualitative focus group and interview study

PubMed Central

Grant, Sabrina; Hodgkinson, James A; Milner, Siobhan L; Martin, Una; Tompson, Alice; Hobbs, FD Richard; Mant, Jonathan; McManus, Richard J; Greenfield, Sheila M

2016-01-01

Background Self-monitoring of blood pressure is common but guidance on how it should be carried out varies and it is currently unclear how such guidance is viewed. Aim To explore patients’ and healthcare professionals’ (HCPs) views and experiences of the use of different self-monitoring regimens to determine what is acceptable and feasible, and to inform future recommendations. Design and setting Thirteen focus groups and four HCP interviews were held, with a total of 66 participants (41 patients and 25 HCPs) from primary and secondary care with and without experience of self-monitoring. Method Standard and shortened self-monitoring protocols were both considered. Focus groups and interviews were recorded, transcribed verbatim, and analysed using the constant comparative method. Results Patients generally supported structured schedules but with sufficient flexibility to allow adaptation to individual routine. They preferred a shorter (3-day) schedule to longer (7-day) regimens. Although HCPs could describe benefits for patients of using a schedule, they were reluctant to recommend a specific schedule. Concerns surrounded the use of different schedules for diagnosis and subsequent monitoring. Appropriate education was seen as vital by all participants to enable a self-monitoring schedule to be followed at home. Conclusion There is not a ‘one size fits all approach’ to developing the optimum protocol from the perspective of users and those implementing it. An approach whereby patients are asked to complete the minimum number of readings required for accurate blood pressure estimation in a flexible manner seems most likely to succeed. Informative advice and guidance should incorporate such flexibility for patients and professionals alike. PMID:27381484

Patients' and clinicians' views on the optimum schedules for self-monitoring of blood pressure: a qualitative focus group and interview study.

PubMed

Grant, Sabrina; Hodgkinson, James A; Milner, Siobhan L; Martin, Una; Tompson, Alice; Hobbs, Fd Richard; Mant, Jonathan; McManus, Richard J; Greenfield, Sheila M

2016-11-01

Self-monitoring of blood pressure is common but guidance on how it should be carried out varies and it is currently unclear how such guidance is viewed. To explore patients' and healthcare professionals' (HCPs) views and experiences of the use of different self-monitoring regimens to determine what is acceptable and feasible, and to inform future recommendations. Thirteen focus groups and four HCP interviews were held, with a total of 66 participants (41 patients and 25 HCPs) from primary and secondary care with and without experience of self-monitoring. Standard and shortened self-monitoring protocols were both considered. Focus groups and interviews were recorded, transcribed verbatim, and analysed using the constant comparative method. Patients generally supported structured schedules but with sufficient flexibility to allow adaptation to individual routine. They preferred a shorter (3-day) schedule to longer (7-day) regimens. Although HCPs could describe benefits for patients of using a schedule, they were reluctant to recommend a specific schedule. Concerns surrounded the use of different schedules for diagnosis and subsequent monitoring. Appropriate education was seen as vital by all participants to enable a self-monitoring schedule to be followed at home. There is not a 'one size fits all approach' to developing the optimum protocol from the perspective of users and those implementing it. An approach whereby patients are asked to complete the minimum number of readings required for accurate blood pressure estimation in a flexible manner seems most likely to succeed. Informative advice and guidance should incorporate such flexibility for patients and professionals alike. © British Journal of General Practice 2016.

Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease: Methodology and Baseline Sample Characteristics.

PubMed

Byun, Min Soo; Yi, Dahyun; Lee, Jun Ho; Choe, Young Min; Sohn, Bo Kyung; Lee, Jun-Young; Choi, Hyo Jung; Baek, Hyewon; Kim, Yu Kyeong; Lee, Yun-Sang; Sohn, Chul-Ho; Mook-Jung, Inhee; Choi, Murim; Lee, Yu Jin; Lee, Dong Woo; Ryu, Seung-Ho; Kim, Shin Gyeom; Kim, Jee Wook; Woo, Jong Inn; Lee, Dong Young

2017-11-01

The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's disease (KBASE) aimed to recruit 650 individuals, aged from 20 to 90 years, to search for new biomarkers of Alzheimer's disease (AD) and to investigate how multi-faceted lifetime experiences and bodily changes contribute to the brain changes or brain pathologies related to the AD process. All participants received comprehensive clinical and neuropsychological evaluations, multi-modal brain imaging, including magnetic resonance imaging, magnetic resonance angiography, [ 11 C]Pittsburgh compound B-positron emission tomography (PET), and [ 18 F]fluorodeoxyglucose-PET, blood and genetic marker analyses at baseline, and a subset of participants underwent actigraph monitoring and completed a sleep diary. Participants are to be followed annually with clinical and neuropsychological assessments, and biannually with the full KBASE assessment, including neuroimaging and laboratory tests. As of March 2017, in total, 758 individuals had volunteered for this study. Among them, in total, 591 participants-291 cognitively normal (CN) old-aged individuals, 74 CN young- and middle-aged individuals, 139 individuals with mild cognitive impairment (MCI), and 87 individuals with AD dementia (ADD)-were enrolled at baseline, after excluding 162 individuals. A subset of participants (n=275) underwent actigraph monitoring. The KBASE cohort is a prospective, longitudinal cohort study that recruited participants with a wide age range and a wide distribution of cognitive status (CN, MCI, and ADD) and it has several strengths in its design and methodologies. Details of the recruitment, study methodology, and baseline sample characteristics are described in this paper.

Febrile illness in healthcare workers caring for Ebola virus disease patients in a high-resource setting.

PubMed

Fink, Douglas; Cropley, Ian; Jacobs, Michael; Mepham, Stephen

2017-01-26

Ebola virus disease (EVD) patients treated in high-resource facilities are cared for by large numbers of healthcare staff. Monitoring these healthcare workers (HCWs) for any illness that may represent transmission of Ebola virus is important both for the individuals and to minimise the community risk. International policies for monitoring HCWs vary considerably and their effectiveness is unknown. Here we describe the United Kingdom (UK) experience of illness in HCWs who cared for three patients who acquired EVD in West Africa. Five of these 93 high-level isolation unit (HLIU) HCWs presented with fever within 21 days of working on the unit; one of these five presented outside of the UK. This article discusses different approaches to monitoring of HCW symptom reporting. The potential impact of these approaches on HLIU staff recruitment, including travel restrictions, is also considered. An international surveillance system enhancing collaboration between national public health authorities may assist HLIU HCW monitoring in case they travel. This article is copyright of The Authors, 2017.

Febrile illness in healthcare workers caring for Ebola virus disease patients in a high-resource setting

PubMed Central

Fink, Douglas; Cropley, Ian; Jacobs, Michael; Mepham, Stephen

2017-01-01

Ebola virus disease (EVD) patients treated in high-resource facilities are cared for by large numbers of healthcare staff. Monitoring these healthcare workers (HCWs) for any illness that may represent transmission of Ebola virus is important both for the individuals and to minimise the community risk. International policies for monitoring HCWs vary considerably and their effectiveness is unknown. Here we describe the United Kingdom (UK) experience of illness in HCWs who cared for three patients who acquired EVD in West Africa. Five of these 93 high-level isolation unit (HLIU) HCWs presented with fever within 21 days of working on the unit; one of these five presented outside of the UK. This article discusses different approaches to monitoring of HCW symptom reporting. The potential impact of these approaches on HLIU staff recruitment, including travel restrictions, is also considered. An international surveillance system enhancing collaboration between national public health authorities may assist HLIU HCW monitoring in case they travel. PMID:28182538

Chronic Obstructive Pulmonary Disease Patients' Experiences of an Enhanced Self-Management Model of Care.

PubMed

Patel, Neil; Jones, Pauline; Adamson, Vikki; Spiteri, Monica; Kinmond, Kathryn

2016-03-01

Chronic obstructive pulmonary disease (COPD) is debilitating and costly. Self-management is championed to empower individuals to better manage their condition and also to efficiently utilize health resources. As a multi-disciplinary team, we conducted focus group research with individuals living with COPD who were participating in a longitudinal study to use an electronic "diary" to monitor, record, and transmit their own health status, plus receiving regular nurse visits. The main aims of the focus groups were to investigate how far individuals embraced the electronic diary and experienced it as an aid to the self-management of their condition. We also looked at the importance of the nurse visits to the process. Thematic analysis revealed that patients responded positively to the use of technology (the electronic diary), including psychological benefits of perceived support offered by the remote symptom surveillance. Findings also showed patients' increased awareness and monitoring of personal symptoms together with an improved understanding of disease self-management. Nurse support emerged as an important "human" factor in the process. In addition, a reduction in hospital admission was observed, thus reducing costs to the health service. © The Author(s) 2015.

Pulse-resolved intensity measurements at a hard X-ray FEL using semi-transparent diamond detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roth, Thomas; Freund, Wolfgang; Boesenberg, Ulrike

Solid-state ionization chambers are presented based on thin diamond crystals that allow pulse-resolved intensity measurements at a hard X-ray free-electron laser (FEL), up to the 4.5 MHz repetition rate that will become available at the European XFEL. Due to the small X-ray absorption of diamond the thin detectors are semi-transparent which eases their use as non-invasive monitoring devices in the beam. FELs are characterized by strong pulse-to-pulse intensity fluctuations due to the self-amplified spontaneous emission (SASE) process and in many experiments it is mandatory to monitor the intensity of each individual pulse. Two diamond detectors with different electrode materials, berylliummore » and graphite, were tested as intensity monitors at the XCS endstation of the Linac Coherent Light Source (LCLS) using the pink SASE beam at 9 keV. The performance is compared with LCLS standard monitors that detect X-rays backscattered from thin SiN foils placed in the beam. In conclusion, the graphite detector can also be used as a beam position monitor although with rather coarse resolution.« less

Pulse-resolved intensity measurements at a hard X-ray FEL using semi-transparent diamond detectors

DOE PAGES

Roth, Thomas; Freund, Wolfgang; Boesenberg, Ulrike; ...

2018-01-01

Solid-state ionization chambers are presented based on thin diamond crystals that allow pulse-resolved intensity measurements at a hard X-ray free-electron laser (FEL), up to the 4.5 MHz repetition rate that will become available at the European XFEL. Due to the small X-ray absorption of diamond the thin detectors are semi-transparent which eases their use as non-invasive monitoring devices in the beam. FELs are characterized by strong pulse-to-pulse intensity fluctuations due to the self-amplified spontaneous emission (SASE) process and in many experiments it is mandatory to monitor the intensity of each individual pulse. Two diamond detectors with different electrode materials, berylliummore » and graphite, were tested as intensity monitors at the XCS endstation of the Linac Coherent Light Source (LCLS) using the pink SASE beam at 9 keV. The performance is compared with LCLS standard monitors that detect X-rays backscattered from thin SiN foils placed in the beam. In conclusion, the graphite detector can also be used as a beam position monitor although with rather coarse resolution.« less

How often are thoughts metacognitive? Findings from research on self-regulated learning, think-aloud protocols, and mind-wandering.

PubMed

Jordano, Megan L; Touron, Dayna R

2018-05-31

Metacognitive monitoring refers to how people evaluate their cognitive performance. An extensive literature examines how accurately individuals engage in monitoring. The question of how often individuals engage in metacognitive monitoring has been largely neglected, although one might expect situational, group, and individual variability in monitoring frequency. We argue that this is a critical omission, given that the frequency of metacognitive monitoring might have important implications for monitoring accuracy and task performance. Within this review, we highlight findings from three literatures, that each provide insight into how often individuals engage in monitoring. To clarify the important links and potential overlaps between these separate bodies of research, we begin by summarizing the metacognitive monitoring literature, including age-related patterns in monitoring accuracy. We then connect these questions regarding spontaneous monitoring, including age-related patterns in spontaneous monitoring, to targeted reviews of the self-regulated learning, think-aloud protocol, and mind-wandering literatures. We discuss situational and dispositional factors believed to influence monitoring accuracy, and propose that the same factors could potentially influence the frequency of spontaneous monitoring. Additionally, we propose that age-related increases in spontaneous monitoring (as suggested by age-related increases in TRI) may contribute to older adults' intact monitoring abilities. It is our hope that this review will encourage increased attention and research on the topic of spontaneous monitoring.

PROCAL: A Set of 40 Peptide Standards for Retention Time Indexing, Column Performance Monitoring, and Collision Energy Calibration.

PubMed

Zolg, Daniel Paul; Wilhelm, Mathias; Yu, Peng; Knaute, Tobias; Zerweck, Johannes; Wenschuh, Holger; Reimer, Ulf; Schnatbaum, Karsten; Kuster, Bernhard

2017-11-01

Beyond specific applications, such as the relative or absolute quantification of peptides in targeted proteomic experiments, synthetic spike-in peptides are not yet systematically used as internal standards in bottom-up proteomics. A number of retention time standards have been reported that enable chromatographic aligning of multiple LC-MS/MS experiments. However, only few peptides are typically included in such sets limiting the analytical parameters that can be monitored. Here, we describe PROCAL (ProteomeTools Calibration Standard), a set of 40 synthetic peptides that span the entire hydrophobicity range of tryptic digests, enabling not only accurate determination of retention time indices but also monitoring of chromatographic separation performance over time. The fragmentation characteristics of the peptides can also be used to calibrate and compare collision energies between mass spectrometers. The sequences of all selected peptides do not occur in any natural protein, thus eliminating the need for stable isotope labeling. We anticipate that this set of peptides will be useful for multiple purposes in individual laboratories but also aiding the transfer of data acquisition and analysis methods between laboratories, notably the use of spectral libraries. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Ecological momentary assessment of daily discrimination experiences and nicotine, alcohol, and drug use among sexual and gender minority individuals.

PubMed

Livingston, Nicholas A; Flentje, Annesa; Heck, Nicholas C; Szalda-Petree, Allen; Cochran, Bryan N

2017-12-01

Sexual and gender minority (SGM) individuals experience elevated rates of minority stress, which has been linked to higher rates of nicotine and substance use. Research on this disparity to date is largely predicated on methodology that is insensitive to within day SGM-based discrimination experiences, or their relation to momentary nicotine and substance use risk. We address this knowledge gap in the current study using ecological momentary assessment (EMA). Fifty SGM individuals, between 18 and 45 years of age, were recruited from an inland northwestern university, regardless of their nicotine or substance use history, and invited to participate in an EMA study. Each were prompted to provide data, six times daily (between 10:00 a.m. and 10:00 p.m.) for 14 days, regarding SGM-based discrimination, other forms of mistreatment, and nicotine, drug, and alcohol use since their last prompt. Discrimination experiences that occurred since individuals' last measurement prompt were associated with greater odds of nicotine and substance use during the same measurement window. Substance use was also more likely to occur in relation to discrimination reported two measurements prior in lagged models. Relative to other forms of mistreatment, discrimination effects were consistently larger in magnitude and became stronger throughout the day/evening. This study adds to existing minority stress research by highlighting the both immediate and delayed correlates of daily SGM-based discrimination experiences. These results also contribute to our understanding of daily stress processes and provide insight into ways we might mitigate these effects using real-time monitoring and intervention technology. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

A Characterization of Individual Differences in Prospective Memory Monitoring Using the Complex Ongoing Serial Task

ERIC Educational Resources Information Center

Savine, Adam C.; McDaniel, Mark A.; Shelton, Jill Talley; Scullin, Michael K.

2012-01-01

Prospective memory--remembering to retrieve and execute future goals--is essential to daily life. Prospective remembering is often achieved through effortful monitoring; however, potential individual differences in monitoring patterns have not been characterized. We propose 3 candidate models to characterize the individual differences present in…

42 CFR 82.15 - How will NIOSH evaluate the completeness and adequacy of individual monitoring data?

Code of Federal Regulations, 2012 CFR

2012-10-01

... adequacy of individual monitoring data? 82.15 Section 82.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES METHODS... adequacy of individual monitoring data? (a) NIOSH will evaluate the completeness and adequacy of an...

42 CFR 82.15 - How will NIOSH evaluate the completeness and adequacy of individual monitoring data?

Code of Federal Regulations, 2014 CFR

2014-10-01

... adequacy of individual monitoring data? 82.15 Section 82.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES METHODS... adequacy of individual monitoring data? (a) NIOSH will evaluate the completeness and adequacy of an...

42 CFR 82.15 - How will NIOSH evaluate the completeness and adequacy of individual monitoring data?

Code of Federal Regulations, 2011 CFR

2011-10-01

... adequacy of individual monitoring data? 82.15 Section 82.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES METHODS... adequacy of individual monitoring data? (a) NIOSH will evaluate the completeness and adequacy of an...

42 CFR 82.15 - How will NIOSH evaluate the completeness and adequacy of individual monitoring data?

Code of Federal Regulations, 2013 CFR

2013-10-01

... adequacy of individual monitoring data? 82.15 Section 82.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES METHODS... adequacy of individual monitoring data? (a) NIOSH will evaluate the completeness and adequacy of an...

Emotional Self-Regulation of Individuals with Autism Spectrum Disorders: Smartwatches for Monitoring and Interaction.

PubMed

Torrado, Juan C; Gomez, Javier; Montoro, Germán

2017-06-11

In this paper, we analyze the needs of individuals with Autism Spectrum Disorders (ASD) to have a pervasive, feasible and non-stigmatizing form of assistance in their emotional self-regulation, in order to ease certain behavioral issues that undermine their mental health throughout their life. We argue the potential of recent widespread wearables, and more specifically smartwatches, to achieve this goal. Then, a smartwatch system that implements a wide range of self-regulation strategies and infers outburst patterns from physiological signals and movement is presented, along with an authoring tool for smartphones that is to be used by caregivers or family members to create and edit these strategies, in an adaptive way. We conducted an intensive experiment with two individuals with ASD who showed varied, representative behavioral responses to their emotional dysregulation. Both users were able to employ effective, customized emotional self-regulation strategies by means of the system, recovering from the majority of mild stress episodes and temper tantrums experienced in the nine days of experiment in their classroom.

Emotional Self-Regulation of Individuals with Autism Spectrum Disorders: Smartwatches for Monitoring and Interaction

PubMed Central

Torrado, Juan C.; Gomez, Javier; Montoro, Germán

2017-01-01

In this paper, we analyze the needs of individuals with Autism Spectrum Disorders (ASD) to have a pervasive, feasible and non-stigmatizing form of assistance in their emotional self-regulation, in order to ease certain behavioral issues that undermine their mental health throughout their life. We argue the potential of recent widespread wearables, and more specifically smartwatches, to achieve this goal. Then, a smartwatch system that implements a wide range of self-regulation strategies and infers outburst patterns from physiological signals and movement is presented, along with an authoring tool for smartphones that is to be used by caregivers or family members to create and edit these strategies, in an adaptive way. We conducted an intensive experiment with two individuals with ASD who showed varied, representative behavioral responses to their emotional dysregulation. Both users were able to employ effective, customized emotional self-regulation strategies by means of the system, recovering from the majority of mild stress episodes and temper tantrums experienced in the nine days of experiment in their classroom. PMID:28604607

Sensing interstitial glucose to nudge active lifestyles (SIGNAL): feasibility of combining novel self-monitoring technologies for persuasive behaviour change.

PubMed

Whelan, Maxine E; Kingsnorth, Andrew P; Orme, Mark W; Sherar, Lauren B; Esliger, Dale W

2017-10-08

Increasing physical activity (PA) reduces the risk of developing diabetes, highlighting the role of preventive medicine approaches. Changing lifestyle behaviours is difficult and is often predicated on the assumption that individuals are willing to change their lifestyles today to reduce the risk of developing disease years or even decades later. The self-monitoring technologies tested in this study will present PA feedback in real time, parallel with acute physiological data. Presenting the immediate health benefits of being more physically active may help enact change by observing the immediate consequences of that behaviour. The present study aims to assess user engagement with the self-monitoring technologies in individuals at moderate-to-high risk of developing type 2 diabetes. 45 individuals with a moderate-to-high risk, aged ≥40 years old and using a compatible smartphone, will be invited to take part in a 7-week protocol. Following 1 week of baseline measurements, participants will be randomised into one of three groups: group 1- glucose feedback followed by biobehavioural feedback (glucose plus PA); group 2-PA feedback followed by biobehavioural feedback; group 3-biobehavioural feedback. A PA monitor and a flash glucose monitor will be deployed during the intervention. Participants will wear both devices throughout the intervention but blinded to feedback depending on group allocation. The primary outcome is the level of participant engagement and will be assessed by device use and smartphone usage. Feasibility will be assessed by the practicality of the technology and screening for diabetes risk. Semistructured interviews will be conducted to explore participant experiences using the technologies. ISRCTN17545949. Registered on 15/05/2017. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Why Nudges Coerce: Experimental Evidence on the Architecture of Regulation.

PubMed

Hill, Adam

2017-07-04

Critics frequently argue that nudges are more covert, less transparent, and more difficult to monitor than traditional regulatory tools. Edward Glaeser, for example, argues that "[p]ublic monitoring of soft paternalism is much more difficult than public monitoring of hard paternalism". As one of the leading proponents of soft paternalism, Cass Sunstein, acknowledges, while "[m]andates and commands are highly visible", soft paternalism, "and some nudges in particular[,] may be invisible". In response to this challenge, proponents of nudging argue that invisibility for any given individual in a particular choice environment is compatible with "careful public scrutiny" of the nudge. This paper offers the first of its kind experimental evidence that tests whether nudges are, in fact, compatible with "careful public scrutiny". Using three sets of experiments, the paper argues that, even when entirely visible, nudges attract less scrutiny than their "hard law" counterparts.

Monitoring of small laboratory animal experiments by a designated web-based database.

PubMed

Frenzel, T; Grohmann, C; Schumacher, U; Krüll, A

2015-10-01

Multiple-parametric small animal experiments require, by their very nature, a sufficient number of animals which may need to be large to obtain statistically significant results.(1) For this reason database-related systems are required to collect the experimental data as well as to support the later (re-) analysis of the information gained during the experiments. In particular, the monitoring of animal welfare is simplified by the inclusion of warning signals (for instance, loss in body weight >20%). Digital patient charts have been developed for human patients but are usually not able to fulfill the specific needs of animal experimentation. To address this problem a unique web-based monitoring system using standard MySQL, PHP, and nginx has been created. PHP was used to create the HTML-based user interface and outputs in a variety of proprietary file formats, namely portable document format (PDF) or spreadsheet files. This article demonstrates its fundamental features and the easy and secure access it offers to the data from any place using a web browser. This information will help other researchers create their own individual databases in a similar way. The use of QR-codes plays an important role for stress-free use of the database. We demonstrate a way to easily identify all animals and samples and data collected during the experiments. Specific ways to record animal irradiations and chemotherapy applications are shown. This new analysis tool allows the effective and detailed analysis of huge amounts of data collected through small animal experiments. It supports proper statistical evaluation of the data and provides excellent retrievable data storage. © The Author(s) 2015.

CIEMAT EXTERNAL DOSIMETRY SERVICE: ISO/IEC 17025 ACCREDITATION AND 3 Y OF OPERATIONAL EXPERIENCE AS AN ACCREDITED LABORATORY.

PubMed

Romero, A M; Rodríguez, R; López, J L; Martín, R; Benavente, J F

2016-09-01

In 2008, the CIEMAT Radiation Dosimetry Service decided to implement a quality management system, in accordance with established requirements, in order to achieve ISO/IEC 17025 accreditation. Although the Service comprises the approved individual monitoring services of both external and internal radiation, this paper is specific to the actions taken by the External Dosimetry Service, including personal and environmental dosimetry laboratories, to gain accreditation and the reflections of 3 y of operational experience as an accredited laboratory. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Photoemission Experiments for Charge Characteristics of Individual Dust Grains

NASA Technical Reports Server (NTRS)

Abbas, M. M.; Spann, James F., Jr.; Craven, Paul D.; West, E.; Pratico, Jared; Scheianu, D.; Tankosic, D.; Venturini, C. C.; Whitaker, Ann F. (Technical Monitor)

2001-01-01

Photoemission experiments with UV radiation have been performed to investigate the microphysics and charge characteristics of individual isolated dust grains of various compositions and sizes by using the electrodynamic balance facility at NASA Marshall Space Flight Center. Dust particles of 1 - 100 micrometer diameter are levitated in a vacuum chamber at pressures approx. 10(exp -5) torr and exposed to a collimated beam of UV radiation in the 120-300 nanometers spectral range from a deuterium lamp source with a MgF2 window. A monochromator is used to select the UV radiation wavelength with a spectral resolution of 8 nanometers. The electrodynamic facility permits measurements of the charge and diameters of particles of known composition, and monitoring of photoemission rates with the incident UV radiation. Experiments have been conducted on Al2O3 and silicate particles, and in particular on JSC-1 Mars regolith simulants, to determine the photoelectron yields and surface equilibrium potentials of dust particles when exposed to UV radiation in the 120-250 micrometers spectral range. A brief discussion of the experimental procedure, the results of photoemission experiments, and comparisons with theoretical models will be presented.

Item generation in the development of an inpatient experience questionnaire: a qualitative study

PubMed Central

2013-01-01

Background Patient experience is a key feature of quality improvement in modern health-care delivery. Measuring patient experience is one of several tools used to assess and monitor the quality of health services. This study aims to develop a tool for assessing patient experience with inpatient care in public hospitals in Hong Kong. Methods Based on the General Inpatient Questionnaire (GIQ) framework of the Care Quality Commission as a discussion guide, a qualitative study involving focus group discussions and in-depth individual interviews with patients was employed to develop a tool for measuring inpatient experience in Hong Kong. Results All participants agreed that a patient satisfaction survey is an important platform for collecting patients’ views on improving the quality of health-care services. Findings of the focus group discussions and in-depth individual interviews identified nine key themes as important hospital quality indicators: prompt access, information provision, care and involvement in decision making, physical and emotional needs, coordination of care, respect and privacy, environment and facilities, handling of patient feedback, and overall care from health-care professionals and quality of care. Privacy, complaint mechanisms, patient involvement, and information provision were further highlighted as particularly important areas for item revision by the in-depth individual interviews. Thus, the initial version of the Hong Kong Inpatient Experience Questionnaire (HKIEQ), comprising 58 core items under nine themes, was developed. Conclusions A set of dimensions and core items of the HKIEQ was developed and the instrument will undergo validity and reliability tests through a validation survey. A valid and reliable tool is important in accurately assessing patient experience with care delivery in hospitals to improve the quality of health-care services. PMID:23835186

Individual variability in the core interthreshold zone as related to body physique, somatotype, and physical constitution.

PubMed

Kakitsuba, Naoshi; Mekjavic, Igor B; Katsuura, Tetsuo

2009-11-01

For evaluating the effect of body physique, somatotype, and physical constitution on individual variability in the core interthreshold zone (CIZ), data from 22 healthy young Japanese male subjects were examined. The experiment was carried out in a climatic chamber in which air temperature was maintained at 20-24 degrees C. The subjects' body physique and the maximum work load were measured. Somatotype was predicted from the Heath-Carter Somatotype method. In addition, factors reflecting physical constitution, for example, susceptibility to heat and cold, and quality of sleep were obtained by questionnaire. The subjects wore a water-perfused suit which was perfused with water at a temperature of 25 degrees C and at a rate of 600 cc/min, and exercised on an ergometer at 50% of their maximum work rate for 10-15 min until their sweating rate increased. They then remained continuously seated without exercise until shivering increased. Rectal temperature (T(re)) and skin temperatures at four sites were monitored by thermistors, and sweating rate was measured at the forehead with a sweat rate monitor. Oxygen uptake was monitored with a gas analyzer. The results showed individual variability in the CIZ. According to the reciprocal cross-inhibition (RCI) theory, thermoafferent information from peripheral and core sensors is activated by T(re), mean skin temperature (T(sk)), and their changes. Since T(sk) was relatively unchanged, the data were selected to eliminate the influence of the core cooling rate on the sensor-to-effector pathway before RCI, and the relationship between the CIZ and the various factors was then analyzed. The results revealed that susceptibility to heat showed a good correlation with the CIZ, indicating that individual awareness of heat may change the CIZ due to thermoregulatory behavior.

The neural correlates of dreaming

PubMed Central

Siclari, F.; Baird, B.; Perogamvros, L.; Bernardi, G.; LaRocque, J. J.; Riedner, B.; Boly, M.; Postle, B. R.; Tononi, G.

2017-01-01

Consciousness never fades during wake. However, if awakened from sleep, sometimes we report dreams and sometimes no experiences. Traditionally, dreaming has been identified with REM sleep, characterized by a wake-like, globally ‘activated’, high-frequency EEG. However, dreaming also occurs in NREM sleep, characterized by prominent low-frequency activity. This challenges our understanding of the neural correlates of conscious experiences in sleep. Using high-density EEG, we contrasted the presence and absence of dreaming within NREM and REM sleep. In both NREM and REM sleep, reports of dream experience were associated with a local decrease in low-frequency activity in posterior cortical regions. High-frequency activity within these regions correlated with specific dream contents. Monitoring this posterior ‘hot zone’ predicted whether an individual reported dreaming or the absence of experiences during NREM sleep in real time, suggesting that it may constitute a core correlate of conscious experiences in sleep. PMID:28394322

The neural correlates of dreaming.

PubMed

Siclari, Francesca; Baird, Benjamin; Perogamvros, Lampros; Bernardi, Giulio; LaRocque, Joshua J; Riedner, Brady; Boly, Melanie; Postle, Bradley R; Tononi, Giulio

2017-06-01

Consciousness never fades during waking. However, when awakened from sleep, we sometimes recall dreams and sometimes recall no experiences. Traditionally, dreaming has been identified with rapid eye-movement (REM) sleep, characterized by wake-like, globally 'activated', high-frequency electroencephalographic activity. However, dreaming also occurs in non-REM (NREM) sleep, characterized by prominent low-frequency activity. This challenges our understanding of the neural correlates of conscious experiences in sleep. Using high-density electroencephalography, we contrasted the presence and absence of dreaming in NREM and REM sleep. In both NREM and REM sleep, reports of dream experience were associated with local decreases in low-frequency activity in posterior cortical regions. High-frequency activity in these regions correlated with specific dream contents. Monitoring this posterior 'hot zone' in real time predicted whether an individual reported dreaming or the absence of dream experiences during NREM sleep, suggesting that it may constitute a core correlate of conscious experiences in sleep.

Optimal experience among teachers: new insights into the work paradox.

PubMed

Bassi, Marta; Delle Fave, Antonella

2012-01-01

Several studies highlighted that individuals perceive work as an opportunity for flow or optimal experience, but not as desirable and pleasant. This finding was defined as the work paradox. The present study addressed this issue among teachers from the perspective of self-determination theory, investigating work-related intrinsic and extrinsic motivation, as well as autonomous and controlled behavior regulation. In Study 1, 14 teachers were longitudinally monitored with Experience Sampling Method for one work week. In Study 2, 184 teachers were administered Flow Questionnaire and Work Preference Inventory, respectively investigating opportunities for optimal experience, and motivational orientations at work. Results showed that work-related optimal experiences were associated with both autonomous regulation and with controlled regulation. Moreover, teachers reported both intrinsic and extrinsic motivation at work, with a prevailing intrinsic orientation. Findings provide novel insights on the work paradox, and suggestions for teachers' well-being promotion.

A Comparison of a Brain-Based Adaptive System and a Manual Adaptable System for Invoking Automation

NASA Technical Reports Server (NTRS)

Bailey, Nathan R.; Scerbo, Mark W.; Freeman, Frederick G.; Mikulka, Peter J.; Scott, Lorissa A.

2004-01-01

Two experiments are presented that examine alternative methods for invoking automation. In each experiment, participants were asked to perform simultaneously a monitoring task and a resource management task as well as a tracking task that changed between automatic and manual modes. The monitoring task required participants to detect failures of an automated system to correct aberrant conditions under either high or low system reliability. Performance on each task was assessed as well as situation awareness and subjective workload. In the first experiment, half of the participants worked with a brain-based system that used their EEG signals to switch the tracking task between automatic and manual modes. The remaining participants were yoked to participants from the adaptive condition and received the same schedule of mode switches, but their EEG had no effect on the automation. Within each group, half of the participants were assigned to either the low or high reliability monitoring task. In addition, within each combination of automation invocation and system reliability, participants were separated into high and low complacency potential groups. The results revealed no significant effects of automation invocation on the performance measures; however, the high complacency individuals demonstrated better situation awareness when working with the adaptive automation system. The second experiment was the same as the first with one important exception. Automation was invoked manually. Thus, half of the participants pressed a button to invoke automation for 10 s. The remaining participants were yoked to participants from the adaptable condition and received the same schedule of mode switches, but they had no control over the automation. The results showed that participants who could invoke automation performed more poorly on the resource management task and reported higher levels of subjective workload. Further, those who invoked automation more frequently performed more poorly on the tracking task and reported higher levels of subjective workload. and the adaptable condition in the second experiment revealed only one significant difference: the subjective workload was higher in the adaptable condition. Overall, the results show that a brain-based, adaptive automation system may facilitate situation awareness for those individuals who are more complacent toward automation. By contrast, requiring operators to invoke automation manually may have some detrimental impact on performance but does appear to increases subjective workload relative to an adaptive system.

10 CFR 20.1502 - Conditions requiring individual monitoring of external and internal occupational dose.

Code of Federal Regulations, 2014 CFR

2014-01-01

... internal occupational dose. 20.1502 Section 20.1502 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Surveys and Monitoring § 20.1502 Conditions requiring individual monitoring of external and internal occupational dose. Each licensee shall monitor exposures to radiation and radioactive...

10 CFR 20.1502 - Conditions requiring individual monitoring of external and internal occupational dose.

Code of Federal Regulations, 2012 CFR

2012-01-01

... internal occupational dose. 20.1502 Section 20.1502 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Surveys and Monitoring § 20.1502 Conditions requiring individual monitoring of external and internal occupational dose. Each licensee shall monitor exposures to radiation and radioactive...

10 CFR 20.1502 - Conditions requiring individual monitoring of external and internal occupational dose.

Code of Federal Regulations, 2011 CFR

2011-01-01

... internal occupational dose. 20.1502 Section 20.1502 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Surveys and Monitoring § 20.1502 Conditions requiring individual monitoring of external and internal occupational dose. Each licensee shall monitor exposures to radiation and radioactive...

10 CFR 20.1502 - Conditions requiring individual monitoring of external and internal occupational dose.

Code of Federal Regulations, 2013 CFR

2013-01-01

... internal occupational dose. 20.1502 Section 20.1502 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Surveys and Monitoring § 20.1502 Conditions requiring individual monitoring of external and internal occupational dose. Each licensee shall monitor exposures to radiation and radioactive...

10 CFR 20.1502 - Conditions requiring individual monitoring of external and internal occupational dose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... internal occupational dose. 20.1502 Section 20.1502 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Surveys and Monitoring § 20.1502 Conditions requiring individual monitoring of external and internal occupational dose. Each licensee shall monitor exposures to radiation and radioactive...

A UK medical devices regulator's perspective on registries.

PubMed

Wilkinson, John; Crosbie, Andy

2016-04-01

Registries are powerful tools to support manufacturers in the fulfilment of their obligations to perform post-market surveillance and post-market clinical follow-up of implantable medical devices. They are also a valuable resource for regulators in support of regulatory action as well as in providing information around the safety of new and innovative technologies. Registries can provide valuable information on the relative performance of both generic types and manufacturer's individual products and they complement other sources of information about device performance such as post-market clinical studies and adverse incident reporting. This paper describes the experience of the UK medical device regulator - the Medicines and Healthcare Products Regulatory Agency (MHRA) - of working with registries to monitor the safety and performance of medical devices. Based upon this experience, the authors identify a number of attributes for a registry which they consider to be key if the registry is to contribute effectively to the work of regulators on patient safety monitoring and medical device regulation.

Results of the SOLCON FREESTAR Total Solar Irradiance measurements

NASA Astrophysics Data System (ADS)

Dewitte, S.; Joukoff, A.; Crommelynck, D.

2003-04-01

The measurement of the Total Solar Irradiance from space is ongoing since 1978. A long term series requires the combination of the time limited measurements of individual measurements. The accuracy of the long term series is limited by the absolute accuracy of the instruments, and by their ageing in space, due to exposure to UV radiation. As a reference for the combination of the different instruments, we use the measurements of the SOLar CONstant (SOLCON) instrument, which is flown regularly on the space shuttle. In this paper we will present the results of the most recent SOLCON flight, which is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) flight foreseen from 16 Jan. 2003 to 1 Feb. 2003. The anticipated results are: 1) comparison of SOLCON with the new instruments Active Cavity Radiometer Irradiance Monitor (ACRIM) III, and 2) the Total Irradiance Monitor (TIM) on the Solar Radiation and Climate Experiment (SORCE) satellite, 3) verification of the ageing of the Variability of IRradiance and Gravity Oscillations (VIRGO) radiometers.

The influence of observers’ sex on attention-demanding performance depends on performers’ sex

PubMed Central

Wang, Lijun; Tan, Jinfeng; Chen, Jiangtao; Chen, Antao

2015-01-01

Post-error slowing (PES) indicates the slower responses after errors than after correct responses. Prior studies mainly focus on how the observation errors influence one own’s performance, there is no study investigating how other’s monitoring influence one own’s performance. Additionally, the issue that whether social context influences the PES effect differently for females and males is still unclear. To address aforementioned issues, we required the participants to interact with a same-sex or opposite-sex partner to complete a color flanker task together (they sat next to each other, Experiment 1). One was the performer (perform the flanker task), and the other was the observer (monitor the error responses of performer). They alternated their roles in two successive blocks. To further verify the role of the interaction context, a control experiment was conducted in the individual context (Experiment 2). The results revealed that (1) larger PES effect was observed in females than in males in the interaction context; (2) the sex difference of PES effect mainly benefited from the opposite-sex interaction; (3) larger PES effect was observed in the interaction context than in the individual context; (4) females’ performance was influenced after an interaction with a same-sex or opposite-sex partner, whereas males’ performance was merely influenced after an interaction with an opposite-sex partner. Taken together, these findings may suggest that (1) interaction context modulates the PES effect differently for females and males; (2) females are more susceptible to social information and hence more effective to adjust the post-error behaviors. PMID:26379574

False memory susceptibility in coma survivors with and without a near-death experience.

PubMed

Martial, Charlotte; Charland-Verville, Vanessa; Dehon, Hedwige; Laureys, Steven

2018-07-01

It has been postulated that memories of near-death experiences (NDEs) could be (at least in part) reconstructions based on experiencers' (NDErs) previous knowledge and could be built as a result of the individual's attempt to interpret the confusing experience. From the point of view of the experiencer, NDE memories are perceived as being unrivalled memories due to its associated rich phenomenology. However, the scientific literature devoted to the cognitive functioning of NDErs in general, and their memory performance in particular, is rather limited. This study examined NDErs' susceptibility to false memories using the Deese-Roediger-McDermott (DRM) paradigm. We included 20 NDErs who reported having had their experience in the context of a life-threatening event (Greyson NDE scale total score ≥7/32) and 20 volunteers (matched for age, gender, education level, and time since brain insult) who reported a life-threatening event but without a NDE. Both groups were presented with DRM lists for a recall task during which they were asked to assign "Remember/Know/Guess" judgements to any recalled response. In addition, they were later asked to complete a post-recall test designed to obtain estimates of activation and monitoring of critical lures. Results demonstrated that NDErs and volunteers were equally likely to produce false memories, but that NDErs recalled them more frequently associated with compelling illusory recollection. Of particular interest, analyses of activation and monitoring estimates suggest that NDErs and volunteers groups were equally likely to think of critical lures, but source monitoring was less successful in NDErs compared to volunteers.

Stability and Noise in the Cyanobacterial Circadian Clock

NASA Astrophysics Data System (ADS)

Mihalcescu, Irina

2008-03-01

Accuracy in cellular function has to be achieved despite random fluctuations (noise) in the concentrations of different molecular constituents inside and outside the cell. Single cell in vivo monitoring reveals that individual cells generate autonomous circadian rhythms in protein abundance. In multi-cellular organisms, the individual cell rhythms appear to be noisy with drifting phases and frequencies. However, the whole organism is significantly more accurate, the temporal precision being achieved most probably via intercellular coupling of the individual noisy oscillators. In cyanobacteria, we have shown that single cell oscillators are impressively stable and a first estimation rules out strong intercellular coupling. Interestingly, these prokaryotes also have the simplest molecular mechanism at the heart of their circadian clock. In the absence of transcriptional activity in vivo, as well alone in vitro, the three clock proteins KaiA, KaiB and KaiC generate a self-sustained circadian oscillation of autophosphorylation and dephosphorylation. Recent chemical kinetics models provide a possible understanding of the three-protein oscillator, but the measured in vivo stability remains yet unexplained. Is the clock stability a built-in property for each bacterium or does a weak intercellular coupling, make them appear like that? To address this question we first theoretically designed our experiment to be able to distinguish coupling, even weak, from phase diffusion. As the precision of our evaluation increases with the length of the experiments, we continuously monitor, for a couple of weeks, mixtures of cell populations with different initial phases. The inherent experimental noise contribution, initially dominant, is reduced by enhanced statistics. In addition, in situ entrainment experiments confirm our ability to detect a coupling of the circadian oscillator to an external force and to describe explicitly the dynamic change of the mean phase. We report a value of the coupling constant that is small compared to the diffusion constant. These results therefore confirm that the cyanobacterial clock stability is a built-in property: the cyanobacterian clock mechanism is not only the simplest but also the most robust.

Goal neglect, fluid intelligence and processing speed: Manipulating instruction load and inter-stimulus interval.

PubMed

Iveson, Matthew H; Della Sala, Sergio; Anderson, Mike; MacPherson, Sarah E

2017-05-01

Goal maintenance is the process where task rules and instructions are kept active to exert their control on behavior. When this process fails, an individual may ignore a rule while performing the task, despite being able to describe it after task completion. Previous research has suggested that the goal maintenance system is limited by the number of concurrent rules which can be maintained during a task, and that this limit is dependent on an individual's level of fluid intelligence. However, the speed at which an individual can process information may also limit their ability to use task rules when the task demands them. In the present study, four experiments manipulated the number of instructions to be maintained by younger and older adults and examined whether performance on a rapid letter-monitoring task was predicted by individual differences in fluid intelligence or processing speed. Fluid intelligence played little role in determining how frequently rules were ignored during the task, regardless of the number of rules to be maintained. In contrast, processing speed predicted the rate of goal neglect in older adults, where increasing the presentation rate of the letter-monitoring task increased goal neglect. These findings suggest that goal maintenance may be limited by the speed at which it can operate. Copyright © 2017. Published by Elsevier B.V.

Recommendations for presymptomatic genetic testing and management of individuals at risk for hereditary transthyretin amyloidosis.

PubMed

Obici, Laura; Kuks, Jan B; Buades, Juan; Adams, David; Suhr, Ole B; Coelho, Teresa; Kyriakides, Theodore

2016-02-01

These recommendations highlight recent experience in genetic counselling for the severe autosomal-dominant, late-onset transthyretin familial amyloid polyneuropathy (TTR-FAP) disease, and present a structured approach towards identification and monitoring of asymptomatic carriers of the mutated gene. The effectiveness of current treatment options is still limited in patients with TTR-FAP beyond stage I. Diagnosis in the early stages of TTR-FAP is essential to prevent or delay the progression of disease. Existing legal and cultural issues differ among countries within Europe. Experts of the European Network for TTR-FAP (ATTReuNET) concluded that genetic counselling for diagnosed individuals and at-risk family members is mostly beneficial and should be carried out with care by trained professionals. Systematic and regular monitoring of an asymptomatic carrier is necessary to detect early signs of TTR-FAP and maximize the effectiveness of treatment. This includes five areas of assessment: history/clinical examination, sensorimotor function, autonomic dysfunction, cardiac function, and renal function. At least two related symptoms and positive biopsy findings are required to confirm diagnosis of TTR-FAP. Early detection of TTR-FAP is essential to improve the prognosis of TTR-FAP. ATTReuNET recommends genetic counselling and routine monitoring for asymptomatic carriers of TTR-FAP.

Guidelines for the use of magnetic resonance imaging in diagnosing and monitoring the treatment of multiple sclerosis: recommendations of the Swedish Multiple Sclerosis Association and the Swedish Neuroradiological Society.

PubMed

Vågberg, M; Axelsson, M; Birgander, R; Burman, J; Cananau, C; Forslin, Y; Granberg, T; Gunnarsson, M; von Heijne, A; Jönsson, L; Karrenbauer, V D; Larsson, E-M; Lindqvist, T; Lycke, J; Lönn, L; Mentesidou, E; Müller, S; Nilsson, P; Piehl, F; Svenningsson, A; Vrethem, M; Wikström, J

2017-01-01

Multiple sclerosis (MS) is associated with inflammatory lesions in the brain and spinal cord. The detection of such inflammatory lesions using magnetic resonance imaging (MRI) is important in the consideration of the diagnosis and differential diagnoses of MS, as well as in the monitoring of disease activity and predicting treatment efficacy. Although there is strong evidence supporting the use of MRI for both the diagnosis and monitoring of disease activity, there is a lack of evidence regarding which MRI protocols to use, the frequency of examinations, and in what clinical situations to consider MRI examination. A national workshop to discuss these issues was held in Stockholm, Sweden, in August 2015, which resulted in a Swedish consensus statement regarding the use of MRI in the care of individuals with MS. The aim of this consensus statement is to provide practical advice for the use of MRI in this setting. The recommendations are based on a review of relevant literature and the clinical experience of workshop attendees. It is our hope that these recommendations will benefit individuals with MS and guide healthcare professionals responsible for their care. © 2016 The Authors. Acta Neurologica Scandinavica published by John Wiley & Sons Ltd.

Infrasound Sensor and Porous-Hose Filter Characterization Results

NASA Astrophysics Data System (ADS)

Hart, D. M.; Harris, J. M.

2008-12-01

The Ground-Based Nuclear Explosion Monitoring Research and Development (GNEM R&D) program at Sandia National Laboratories (SNL) is regarded as the primary center for unbiased expertise in testing and evaluation of geophysical sensors and instrumentation for nuclear explosion monitoring. Over the past year much of our work has focused in the area of infrasound sensor characterization through the continuing development of an infrasound sensor characterization test-bed. Our main areas of focus have been in new sensor characterization and understanding the effects of porous-hose filters for reducing acoustic background signals. Three infrasound sensors were evaluated for characteristics of instrument response, linearity and self-noise. The sensors tested were Chaparral Physics model 2.5 low-gain, New Mexico Tech All-Sensor and the Inter-Mountain Labs model SS avalanche sensor. For the infrasound sensors tested, the test results allow us to conclude that two of the three sensors had sufficiently quiet noise floor to be at or below the Acoustic low-noise model from 0.1 to 7 Hz, which make those sensors suitable to explosion monitoring. The other area of focus has been to understand the characteristics of porous-hose filters used at some monitoring sites. For this, an experiment was designed in which two infrasound sensors were co- located. One sensor was connected to a typical porous-hose spatial filter consisting of eight individual hoses covering a 30m aperture and the second sensor was left open to unimpeded acoustic input. Data were collected for several days, power spectrum computed for two-hour windows and the relative gain of the porous-hose filters were estimated by dividing the power spectrum. The porous-hose filter appears to attenuate less than 3 dB (rel 1 Pa**2/Hz) below 0.1 Hz and as much as 25 dB at 1 Hz and between 20 to 10 dB above 10 Hz. Several more experiments will be designed to address the effects of different characteristics of the individual porous-hoses, such as length, number and geometric arrangement. This work directly impacts the Ground-Based Nuclear Explosion Monitoring mission by providing a facility, equipment, and personnel to give the operational monitoring agencies confidence in deployed instrumentation and capability for mission success.

Gas chromatography: Possible application of advanced instrumentation developed for solar system exploration to space station cabin atmospheres

NASA Technical Reports Server (NTRS)

Carle, G. C.

1985-01-01

Gas chromatography (GC) technology was developed for flight experiments in solar system exploration. The GC is a powerful analytical technique with simple devices separating individual components from complex mixtures to make very sensitive quantitative and qualitative measurements. It monitors samples containing mixtures of fixed gases and volatile organic molecules. The GC was used on the Viking mission in support of life detection experiments and on the Pioneer Venus Large Probe to determine the composition of the venusian atmosphere. A flight GC is under development to study the progress and extent of STS astronaut denitrogenation prior to extravehicular activity. Advanced flight GC concepts and systems for future solar system exploration are also studied. Studies include miniature ionization detectors and associated control systems capable of detecting from ppb up to 100% concentration levels. Further miniaturization is investigated using photolithography and controlled chemical etching in silicon wafers. Novel concepts such as ion mobility drift spectroscopy and multiplex gas chromatography are also developed for future flight experiments. These powerful analytical concepts and associated hardware are ideal for the monitoring of cabin atmospheres containing potentially dangerous volatile compounds.

HappyFace as a generic monitoring tool for HEP experiments

NASA Astrophysics Data System (ADS)

Kawamura, Gen; Magradze, Erekle; Musheghyan, Haykuhi; Quadt, Arnulf; Rzehorz, Gerhard

2015-12-01

The importance of monitoring on HEP grid computing systems is growing due to a significant increase in their complexity. Computer scientists and administrators have been studying and building effective ways to gather information on and clarify a status of each local grid infrastructure. The HappyFace project aims at making the above-mentioned workflow possible. It aggregates, processes and stores the information and the status of different HEP monitoring resources into the common database of HappyFace. The system displays the information and the status through a single interface. However, this model of HappyFace relied on the monitoring resources which are always under development in the HEP experiments. Consequently, HappyFace needed to have direct access methods to the grid application and grid service layers in the different HEP grid systems. To cope with this issue, we use a reliable HEP software repository, the CernVM File System. We propose a new implementation and an architecture of HappyFace, the so-called grid-enabled HappyFace. It allows its basic framework to connect directly to the grid user applications and the grid collective services, without involving the monitoring resources in the HEP grid systems. This approach gives HappyFace several advantages: Portability, to provide an independent and generic monitoring system among the HEP grid systems. Eunctionality, to allow users to perform various diagnostic tools in the individual HEP grid systems and grid sites. Elexibility, to make HappyFace beneficial and open for the various distributed grid computing environments. Different grid-enabled modules, to connect to the Ganga job monitoring system and to check the performance of grid transfers among the grid sites, have been implemented. The new HappyFace system has been successfully integrated and now it displays the information and the status of both the monitoring resources and the direct access to the grid user applications and the grid collective services.

Centralized sanctioning and legitimate authority promote cooperation in humans.

PubMed

Baldassarri, Delia; Grossman, Guy

2011-07-05

Social sanctioning is widely considered a successful strategy to promote cooperation among humans. In situations in which individual and collective interests are at odds, incentives to free-ride induce individuals to refrain from contributing to public goods provision. Experimental evidence from public goods games shows that when endowed with sanctioning powers, conditional cooperators can discipline defectors, thus leading to greater levels of cooperation. However, extant evidence is based on peer punishment institutions, whereas in complex societies, systems of control are often centralized: for instance, we do not sanction our neighbors for driving too fast, the police do. Here we show the effect of centralized sanctioning and legitimate authority on cooperation. We designed an adaptation of the public goods game in which sanctioning power is given to a single monitor, and we experimentally manipulated the process by which the monitor is chosen. To increase the external validity of the study, we conducted lab-in-the-field experiments involving 1,543 Ugandan farmers from 50 producer cooperatives. This research provides evidence of the effectiveness of centralized sanctioning and demonstrates the causal effect of legitimacy on cooperation: participants are more responsive to the authority of an elected monitor than a randomly chosen monitor. Our essay contributes to the literature on the evolution of cooperation by introducing the idea of role differentiation. In complex societies, cooperative behavior is not only sustained by mechanisms of selection and reciprocity among peers, but also by the legitimacy that certain actors derive from their position in the social hierarchy.

Integrated biomarker response index used in laboratory exposure of the mussel Mytilus edulis to water accommodated fractions of crude oil

NASA Astrophysics Data System (ADS)

Yuan, Mengqi; Wang, You; Zhang, Xinxin; Hu, Shunxin; Tang, Xuexi

2017-03-01

Oil pollution is a serious environmental problem in coastal areas and to set up a quantitative evaluation method in monitoring the environmental pollution is of great importance. Individuals of Mytilus edulis, collected from the coastal area of Qingdao, were thus exposed to the water accommodated fractions (WAFs) of crude oil under controlled lab conditions. Mussels were exposed to different concentrations of WAFs for 96h acute toxicity experiment and 15d chronic toxicity experiment, a 7d restoration experiment was conducted after toxicity experiment as well. The activities of the antioxidant enzymes (CAT, GST, GPx and GR) were measured in gills of mussels. The purpose of the study was to screen out a series of sensitive biomarkers and set up an Integrated Biomarker Response index (IBR) for marine oil pollution monitoring. Results showed: (1) WAFs exposure induced the increased activities of CAT, GST, GPx and GR in gills, revealing a stimulation effect on the antioxidant system. Activities of enzymes were more significantly altered in response to higher concentrations of WAFs (2.3 and 5.0 mg.L-1) than lower concentrations (0.5 and 1.1 mg.L-1). After restoration experiment, the activities decreased to the initial levels. (2) IBR was set up base on the laboratory experiment, which showed a positive relationship with WAFs exposure concentrations. Therefore, IBR was suggested to be a potentially useful tool in assessing the oil pollution.

Measurement of Bremsstrahlung radiation for in vivo monitoring of 14C tracer distribution between fruit and roots of kiwifruit (Actinidia arguta) cuttings.

PubMed

Black, Marykate Z; Minchin, Peter E H; Gould, Nick; Patterson, Kevin J; Clearwater, Michael J

2012-10-01

In vivo measurements of (14)C tracer distribution have usually involved monitoring the β(-) particles produced as (14)C decays. These particles are only detectable over short distances, limiting the use of this technique to thin plant material. In the present experiments, X-ray detectors were used to monitor the Bremsstrahlung radiation emitted since β(-) particles were absorbed in plant tissues. Bremsstrahlung radiation is detectable through larger tissue depths. The aim of these experiments was to demonstrate the Bremsstrahlung method by monitoring in vivo tracer-labelled photosynthate partitioning in small kiwifruit (Actinidia arguta (Siebold & Zucc.) Planch. ex Miq.) plants in response to root pruning. A source shoot, consisting of four leaves, was pulse labelled with (14)CO(2). Detectors monitored import into a fruit and the root system, and export from a source leaf. Repeat pulse labelling enabled the comparison of pre- and post-treatment observations within an individual plant. Diurnal trends were observed in the distribution of tracer, with leaf export reduced at night. Tracer accumulated in the roots declined after approximately 48 h, which may have resulted from export of (14)C from the roots in carbon skeletons. Cutting off half the roots did not affect tracer distribution to the remaining half. Tracer distribution to the fruit was increased after root pruning, demonstrating the higher competitive strength of the fruit than the roots for carbohydrate supply. Increased partitioning to the fruit following root pruning has also been demonstrated in kiwifruit field trials.

Overview of GSE as a multifunctional GUI

NASA Astrophysics Data System (ADS)

Kurtovich, Boyan; Malangone, Fabio; Voss, David L.; Carssow, Douglas B.; Fritz, Theodore A.; Mavretic, Anton

2009-08-01

Ground Support Equipment (GSE) [1] is a versatile and multifunctional graphical user interface (GUI) and a software/hardware platform. It is a custom-designed system executed in the LabVIEW programming language to serve as an instrument health monitor for the Loss Cone Imager (LCI) satellite project. GSE mimics the behavior of the onboard Experiment Computer System (ECS). Its functions comprise the measurement of voltage, current, and power, as well as acting as a safety mechanism in case of any anomalous condition (e.g., over-current and/or over-voltage situation). Individual log files record the sessions during which data is gathered and analyzed. Safety/warning alarm flags shall be 'visible' from any individual window/tab. Analog-to-Digital Conversion (ADC) particle group measurements will be displayed on six individual panels. GSE will be supplemented with a comprehensive user's manual for added clarity.

Design of ecoregional monitoring in conservation areas of high-latitude ecosystems under contemporary climate change

USGS Publications Warehouse

Beever, Erik A.; Woodward, Andrea

2011-01-01

Land ownership in Alaska includes a mosaic of federally managed units. Within its agency’s context, each unit has its own management strategy, authority, and resources of conservation concern, many of which are migratory animals. Though some units are geographically isolated, many are nevertheless linked by paths of abiotic and biotic flows, such as rivers, air masses, flyways, and terrestrial and aquatic migration routes. Furthermore, individual land units exist within the context of a larger landscape pattern of shifting conditions, requiring managers to understand at larger spatial scales the status and trends in the synchrony and spatial concurrence of species and associated suitable habitats. Results of these changes will determine the ability of Alaska lands to continue to: provide habitat for local and migratory species; absorb species whose ranges are shifting northward; and experience mitigation or exacerbation of climate change through positive and negative atmospheric feedbacks. We discuss the geographic and statutory contexts that influence development of ecological monitoring; argue for the inclusion of significant amounts of broad-scale monitoring; discuss the importance of defining clear programmatic and monitoring objectives; and draw from lessons learned from existing long-term, broad-scale monitoring programs to apply to the specific contexts relevant to high-latitude protected areas such as those in Alaska. Such areas are distinguished by their: marked seasonality; relatively large magnitudes of contemporary change in climatic parameters; and relative inaccessibility due to broad spatial extent, very low (or zero) road density, and steep and glaciated areas. For ecological monitoring to effectively support management decisions in high-latitude areas such as Alaska, a monitoring program ideally would be structured to address the actual spatial and temporal scales of relevant processes, rather than the artificial boundaries of individual land-management units. Heuristic models provide a means by which to integrate understanding of ecosystem structure, composition, and function, in the midst of numerous ecosystem drivers.

Comparison of a brain-based adaptive system and a manual adaptable system for invoking automation.

PubMed

Bailey, Nathan R; Scerbo, Mark W; Freeman, Frederick G; Mikulka, Peter J; Scott, Lorissa A

2006-01-01

Two experiments are presented examining adaptive and adaptable methods for invoking automation. Empirical investigations of adaptive automation have focused on methods used to invoke automation or on automation-related performance implications. However, no research has addressed whether performance benefits associated with brain-based systems exceed those in which users have control over task allocations. Participants performed monitoring and resource management tasks as well as a tracking task that shifted between automatic and manual modes. In the first experiment, participants worked with an adaptive system that used their electroencephalographic signals to switch the tracking task between automatic and manual modes. Participants were also divided between high- and low-reliability conditions for the system-monitoring task as well as high- and low-complacency potential. For the second experiment, participants operated an adaptable system that gave them manual control over task allocations. Results indicated increased situation awareness (SA) of gauge instrument settings for individuals high in complacency potential using the adaptive system. In addition, participants who had control over automation performed more poorly on the resource management task and reported higher levels of workload. A comparison between systems also revealed enhanced SA of gauge instrument settings and decreased workload in the adaptive condition. The present results suggest that brain-based adaptive automation systems may enhance perceptual level SA while reducing mental workload relative to systems requiring user-initiated control. Potential applications include automated systems for which operator monitoring performance and high-workload conditions are of concern.

Empty rituals? A qualitative study of users' experience of monitoring & evaluation systems in HIV interventions in western India.

PubMed

Shukla, Anuprita; Teedon, Paul; Cornish, Flora

2016-11-01

In global health initiatives, particularly in the context of private philanthropy and its 'business minded' approach, detailed programme data plays an increasing role in informing assessments, improvements, evaluations, and ultimately continuation or discontinuation of funds for individual programmes. The HIV/AIDS literature predominantly treats monitoring as unproblematic. However, the social science of audit and indicators emphasises the constitutive power of indicators, noting that their effects at a grassroots level are often at odds with the goals specified in policy. This paper investigates users' experiences of Monitoring and Evaluation (M&E) systems in the context of HIV interventions in western India. Six focus groups (totalling 51 participants) were held with employees of 6 different NGOs working for government or philanthropy-funded HIV interventions for sex workers in western India. Ten donor employees were interviewed. Thematic analysis was conducted. NGO employees described a major gap between what they considered their "real work" and the indicators used to monitor it. They could explain the official purposes of M&E systems in terms of programme improvement and financial accountability. More cynically, they valued M&E experience on their CVs and the rhetorical role of data in demonstrating their achievements. They believed that inappropriate and unethical means were being used to meet targets, including incentives and coercion, and criticised indicators for being misleading and inflexible. Donor employees valued the role of M&E in programme improvement, financial accountability, and professionalising NGO-donor relationships. However, they were suspicious that NGOs might be falsifying data, criticised the insensitivity of indicators, and complained that data were under-used. For its users, M& E appears an 'empty ritual', enacted because donors require it, but not put to local use. In this context, monitoring is constituted as an instrument of performance management rather than as a means of rational programme improvement. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

The effects of music relaxation and muscle relaxation techniques on sleep quality and emotional measures among individuals with posttraumatic stress disorder

PubMed Central

Blanaru, Monica; Bloch, Boaz; Vadas, Limor; Arnon, Zahi; Ziv, Naomi; Kremer, Ilana; Haimov, Iris

2012-01-01

Posttraumatic stress disorder (PTSD), an anxiety disorder with lifetime prevalence of 7.8%, is characterized by symptoms that develop following exposure to traumatic life events and that cause an immediate experience of intense fear, helplessness or horror. PTSD is marked by recurrent nightmares typified by the recall of intrusive experiences and by extended disturbance throughout sleep. Individuals with PTSD respond poorly to drug treatments for insomnia. The disadvantages of drug treatment for insomnia underline the importance of non-pharmacological alternatives. Thus, the present study had three aims: first, to compare the efficiency of two relaxation techniques (muscular relaxation and progressive music relaxation) in alleviating insomnia among individuals with PTSD using both objective and subjective measures of sleep quality; second, to examine whether these two techniques have different effects on psychological indicators of PTSD, such as depression and anxiety; and finally, to examine how initial PTSD symptom severity and baseline emotional measures are related to the efficiency of these two relaxation methods. Thirteen PTSD patients with no other major psychiatric or neurological disorders participated in the study. The study comprised one seven-day running-in, no-treatment period, followed by two seven-day experimental periods. The treatments constituted either music relaxation or muscle relaxation techniques at desired bedtime. These treatments were randomly assigned. During each of these three experimental periods, subjects' sleep was continuously monitored with a wrist actigraph (Ambulatory Monitoring, Inc.), and subjects were asked to fill out several questionnaires concerned with a wide spectrum of issues, such as sleep, depression, and anxiety. Analyses revealed a significant increase in objective and subjective sleep efficiency and a significant reduction in depression level following music relaxation. Moreover, following music relaxation, a highly significant negative correlation was found between improvement in objective sleep efficiency and reduction in depression scale. The study's findings provide evidence that music relaxation at bedtime can be used as treatment for insomnia among individuals with PTSD. PMID:25478114

The face of equipoise - delivering a structured education programme within a randomized controlled trial: qualitative study

PubMed Central

2014-01-01

Background In trials of behavioural interventions, the individuals who deliver the intervention are in a position of key influence on the success of the trial. Their fidelity to the intervention is crucial. Yet little is understood about the experiences of this group of trial personnel. This study aimed to investigate the views and experiences of educators who delivered a structured education intervention to people with type 2 diabetes, which incorporated training in self-monitoring of either blood glucose (SMBG) or urine glucose (SMUG) as part of a randomized controlled trial (RCT). Methods Educators’ views were explored through focus groups before and after training (N = 18) and approximately 1 year into the trial (N = 14), and semi-structured telephone interviews at approximately 2 years (N = 7). Analysis was based on the constant comparative method. Results Educators held preferences regarding the intervention variants; thus, they were not in individual equipoise. Training raised awareness of preferences and their potential to impact on delivery. Educators were confident in their unbiased delivery, but acknowledged the challenges involved. Concealing their preferences was helped by a sense of professionalism, the patient-centred nature of the intervention, and concessions in the trial protocol (enabling participants to swap monitoring methods if needed). Commitment to unbiased delivery was explained through a desire for evidence-based knowledge in the contentious area of SMBG. Conclusions The findings provide insight into a previously unexplored group of trial personnel - intervention deliverers in trials of behavioural interventions - which will be useful to those designing and running similar trials. Rather than individual equipoise, it is intervention deliverers’ awareness of personal preferences and their potential impact on the trial outcome that facilitates unbiased delivery. Further, awareness of community equipoise, the need for evidence, and relevance to the individual enhance commitment to the RCT. Trial registration ISRCTN95696668 PMID:24405854

Visual monitoring of autonomous life sciences experimentation

NASA Technical Reports Server (NTRS)

Blank, G. E.; Martin, W. N.

1987-01-01

The design and implementation of a computerized visual monitoring system to aid in the monitoring and control of life sciences experiments on board a space station was investigated. A likely multiprocessor design was chosen, a plausible life science experiment with which to work was defined, the theoretical issues involved in the programming of a visual monitoring system for the experiment was considered on the multiprocessor, a system for monitoring the experiment was designed, and simulations of such a system was implemented on a network of Apollo workstations.

Determination of Caffeine in Beverages by Capillary Zone Electrophoresis: An Experiment for the Undergraduate Analytical Laboratory

NASA Astrophysics Data System (ADS)

Conte, Eric D.; Barry, Eugene F.; Rubinstein, Harry

1996-12-01

Certain individuals may be sensitive to specific compounds in comsumer products. It is important to quantify these analytes in food products in order to monitor their intake. Caffeine is one such compound. Determination of caffeine in beverages by spectrophotometric procedures requires an extraction procedure, which can prove time-consuming. Although the corresponding determination by HPLC allows for a direct injection, capillary zone electrophoresis provides several advantages such as extremely low solvent consumption, smaller sample volume requirements, and improved sensitivity.

Hands-On Experiences in Deploying Cost-Effective Ambient-Assisted Living Systems

PubMed Central

Dasios, Athanasios; Gavalas, Damianos; Pantziou, Grammati; Konstantopoulos, Charalampos

2015-01-01

Older adults’ preferences to remain independent in their own homes along with the high costs of nursing home care have motivated the development of Ambient Assisted Living (AAL) technologies which aim at improving the safety, health conditions and wellness of the elderly. This paper reports hands-on experiences in designing, implementing and operating UbiCare, an AAL based prototype system for elderly home care monitoring. The monitoring is based on the recording of environmental parameters like temperature and light intensity as well as micro-level incidents which allows one to infer daily activities like moving, sitting, sleeping, usage of electrical appliances and plumbing components. The prototype is built upon inexpensive, off-the-shelf hardware (e.g., various sensors, Arduino microcontrollers, ZigBee-compatible wireless communication modules) and license-free software, thereby ensuring low system deployment costs. The network comprises nodes placed in a house’s main rooms or mounted on furniture, one wearable node, one actuator node and a centralized processing element (coordinator). Upon detecting significant deviations from the ordinary activity patterns of individuals and/or sudden falls, the system issues automated alarms which may be forwarded to authorized caregivers via a variety of communication channels. Furthermore, measured environmental parameters and activity incidents may be monitored through standard web interfaces. PMID:26094631

Hands-On Experiences in Deploying Cost-Effective Ambient-Assisted Living Systems.

PubMed

Dasios, Athanasios; Gavalas, Damianos; Pantziou, Grammati; Konstantopoulos, Charalampos

2015-06-18

Older adults' preferences to remain independent in their own homes along with the high costs of nursing home care have motivated the development of Ambient Assisted Living (AAL) technologies which aim at improving the safety, health conditions and wellness of the elderly. This paper reports hands-on experiences in designing, implementing and operating UbiCare, an AAL based prototype system for elderly home care monitoring. The monitoring is based on the recording of environmental parameters like temperature and light intensity as well as micro-level incidents which allows one to infer daily activities like moving, sitting, sleeping, usage of electrical appliances and plumbing components. The prototype is built upon inexpensive, off-the-shelf hardware (e.g., various sensors, Arduino microcontrollers, ZigBee-compatible wireless communication modules) and license-free software, thereby ensuring low system deployment costs. The network comprises nodes placed in a house's main rooms or mounted on furniture, one wearable node, one actuator node and a centralized processing element (coordinator). Upon detecting significant deviations from the ordinary activity patterns of individuals and/or sudden falls, the system issues automated alarms which may be forwarded to authorized caregivers via a variety of communication channels. Furthermore, measured environmental parameters and activity incidents may be monitored through standard web interfaces.

Multi-gradient echo MR thermometry for monitoring of the near-field area during MR-guided high intensity focused ultrasound heating

NASA Astrophysics Data System (ADS)

Lam, Mie K.; de Greef, Martijn; Bouwman, Job G.; Moonen, Chrit T. W.; Viergever, Max A.; Bartels, Lambertus W.

2015-10-01

The multi-gradient echo MR thermometry (MGE MRT) method is proposed to use at the interface of the muscle and fat layers found in the abdominal wall, to monitor MR-HIFU heating. As MGE MRT uses fat as a reference, it is field-drift corrected. Relative temperature maps were reconstructed by subtracting absolute temperature maps. Because the absolute temperature maps are reconstructed of individual scans, MGE MRT provides the flexibility of interleaved mapping of temperature changes between two arbitrary time points. The method’s performance was assessed in an ex vivo water bath experiment. An ex vivo HIFU experiment was performed to show the method’s ability to monitor heating of consecutive HIFU sonications and to estimate cooling time constants, in the presence of field drift. The interleaved use between scans of a clinical protocol was demonstrated in vivo in a patient during a clinical uterine fibroid treatment. The relative temperature measurements were accurate (mean absolute error 0.3 °C) and provided excellent visualization of the heating of consecutive HIFU sonications. Maps were reconstructed of estimated cooling time constants and mean ROI values could be well explained by the applied heating pattern. Heating upon HIFU sonication and subsequent cooling could be observed in the in vivo demonstration.

Cognitive Abilities, Monitoring Confidence, and Control Thresholds Explain Individual Differences in Heuristics and Biases

PubMed Central

Jackson, Simon A.; Kleitman, Sabina; Howie, Pauline; Stankov, Lazar

2016-01-01

In this paper, we investigate whether individual differences in performance on heuristic and biases tasks can be explained by cognitive abilities, monitoring confidence, and control thresholds. Current theories explain individual differences in these tasks by the ability to detect errors and override automatic but biased judgments, and deliberative cognitive abilities that help to construct the correct response. Here we retain cognitive abilities but disentangle error detection, proposing that lower monitoring confidence and higher control thresholds promote error checking. Participants (N = 250) completed tasks assessing their fluid reasoning abilities, stable monitoring confidence levels, and the control threshold they impose on their decisions. They also completed seven typical heuristic and biases tasks such as the cognitive reflection test and Resistance to Framing. Using structural equation modeling, we found that individuals with higher reasoning abilities, lower monitoring confidence, and higher control threshold performed significantly and, at times, substantially better on the heuristic and biases tasks. Individuals with higher control thresholds also showed lower preferences for risky alternatives in a gambling task. Furthermore, residual correlations among the heuristic and biases tasks were reduced to null, indicating that cognitive abilities, monitoring confidence, and control thresholds accounted for their shared variance. Implications include the proposal that the capacity to detect errors does not differ between individuals. Rather, individuals might adopt varied strategies that promote error checking to different degrees, regardless of whether they have made a mistake or not. The results support growing evidence that decision-making involves cognitive abilities that construct actions and monitoring and control processes that manage their initiation. PMID:27790170

Cognitive Abilities, Monitoring Confidence, and Control Thresholds Explain Individual Differences in Heuristics and Biases.

PubMed

Jackson, Simon A; Kleitman, Sabina; Howie, Pauline; Stankov, Lazar

2016-01-01

In this paper, we investigate whether individual differences in performance on heuristic and biases tasks can be explained by cognitive abilities, monitoring confidence, and control thresholds. Current theories explain individual differences in these tasks by the ability to detect errors and override automatic but biased judgments, and deliberative cognitive abilities that help to construct the correct response. Here we retain cognitive abilities but disentangle error detection, proposing that lower monitoring confidence and higher control thresholds promote error checking. Participants ( N = 250) completed tasks assessing their fluid reasoning abilities, stable monitoring confidence levels, and the control threshold they impose on their decisions. They also completed seven typical heuristic and biases tasks such as the cognitive reflection test and Resistance to Framing. Using structural equation modeling, we found that individuals with higher reasoning abilities, lower monitoring confidence, and higher control threshold performed significantly and, at times, substantially better on the heuristic and biases tasks. Individuals with higher control thresholds also showed lower preferences for risky alternatives in a gambling task. Furthermore, residual correlations among the heuristic and biases tasks were reduced to null, indicating that cognitive abilities, monitoring confidence, and control thresholds accounted for their shared variance. Implications include the proposal that the capacity to detect errors does not differ between individuals. Rather, individuals might adopt varied strategies that promote error checking to different degrees, regardless of whether they have made a mistake or not. The results support growing evidence that decision-making involves cognitive abilities that construct actions and monitoring and control processes that manage their initiation.

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Code of Federal Regulations, 2011 CFR

2011-07-01

... there any special provision regarding my individual filter turbidity monitoring? 141.564 Section 141.564... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Code of Federal Regulations, 2014 CFR

2014-07-01

... there any special provision regarding my individual filter turbidity monitoring? 141.564 Section 141.564... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Code of Federal Regulations, 2010 CFR

2010-07-01

... there any special provision regarding my individual filter turbidity monitoring? 141.564 Section 141.564... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Code of Federal Regulations, 2013 CFR

2013-07-01

... there any special provision regarding my individual filter turbidity monitoring? 141.564 Section 141.564... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Code of Federal Regulations, 2012 CFR

2012-07-01

... there any special provision regarding my individual filter turbidity monitoring? 141.564 Section 141.564... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

Feasibility and validity of computerized ambulatory monitoring in stroke patients.

PubMed

Johnson, E I; Sibon, I; Renou, P; Rouanet, F; Allard, M; Swendsen, J

2009-11-10

Computerized ambulatory monitoring provides real-time assessments of clinical outcomes in natural contexts, and it has been increasingly applied in recent years to investigate symptom expression in a wide range of disorders. The purpose of this study was to examine the feasibility and validity of this data collection strategy with adult stroke patients. Forty-eight individuals (75% of the contacted sample) agreed to participate in the current study and were instructed to complete electronic interviews using a personal digital assistant 5 times per day over a 1-week period. More than 80% of programmed assessments were completed by the sample, and no evidence was found for fatigue effects. Expected patterns of associations were observed among daily life variables, and data collected through ambulatory monitoring were significantly correlated with standard clinic-based measures of similar constructs. Support was found for the feasibility and validity of computerized ambulatory monitoring with stroke patients. The application of these novel methods with stroke patients should provide complementary information that is inaccessible to standard hospital-based assessments and permit increased understanding of the significance of clinical results and test scores for daily life experience.

Metal oxide nanoparticle mediated enhanced Raman scattering and its use in direct monitoring of interfacial chemical reactions.

PubMed

Li, Li; Hutter, Tanya; Finnemore, Alexander S; Huang, Fu Min; Baumberg, Jeremy J; Elliott, Stephen R; Steiner, Ullrich; Mahajan, Sumeet

2012-08-08

Metal oxide nanoparticles (MONPs) have widespread usage across many disciplines, but monitoring molecular processes at their surfaces in situ has not been possible. Here we demonstrate that MONPs give highly enhanced (×10(4)) Raman scattering signals from molecules at the interface permitting direct monitoring of their reactions, when placed on top of flat metallic surfaces. Experiments with different metal oxide materials and molecules indicate that the enhancement is generic and operates at the single nanoparticle level. Simulations confirm that the amplification is principally electromagnetic and is a result of optical modulation of the underlying plasmonic metallic surface by MONPs, which act as scattering antennae and couple light into the confined region sandwiched by the underlying surface. Because of additional functionalities of metal oxides as magnetic, photoelectrochemical and catalytic materials, enhanced Raman scattering mediated by MONPs opens up significant opportunities in fundamental science, allowing direct tracking and understanding of application-specific transformations at such interfaces. We show a first example by monitoring the MONP-assisted photocatalytic decomposition reaction of an organic dye by individual nanoparticles.

42 CFR 82.16 - How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed...

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed dose? 82.16 Section 82.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES...

42 CFR 82.16 - How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed dose? 82.16 Section 82.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES...

42 CFR 82.16 - How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed dose? 82.16 Section 82.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES...

42 CFR 82.16 - How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed dose? 82.16 Section 82.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES...

42 CFR 82.16 - How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false How will NIOSH add to monitoring data to remedy limitations of individual monitoring and missed dose? 82.16 Section 82.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES...

A Study of States' Monitoring and Improvement Practices under the Individuals with Disabilities Education Act. NCSER 2011-3001

ERIC Educational Resources Information Center

Bollmer, Julie; Cronin, Roberta; Brauen, Marsha; Howell, Bethany; Fletcher, Philip; Gonin, Rene; Jenkins, Frank

2010-01-01

The Study of Monitoring and Improvement Practices under the Individuals with Disabilities Education Act (IDEA) examined how states monitored the implementation of IDEA by local special education and early intervention services programs. State monitoring and improvement practices in 2004-05 and 2006-07 were the focus of the study. Prior to the…

Battery management system with distributed wireless sensors

DOEpatents

Farmer, Joseph C.; Bandhauer, Todd M.

2016-02-23

A system for monitoring parameters of an energy storage system having a multiplicity of individual energy storage cells. A radio frequency identification and sensor unit is connected to each of the individual energy storage cells. The radio frequency identification and sensor unit operates to sense the parameter of each individual energy storage cell and provides radio frequency transmission of the parameters of each individual energy storage cell. A management system monitors the radio frequency transmissions from the radio frequency identification and sensor units for monitoring the parameters of the energy storage system.

A method for the automated long-term monitoring of three-spined stickleback Gasterosteus aculeatus shoal dynamics.

PubMed

Kleinhappel, T K; Al-Zoubi, A; Al-Diri, B; Burman, O; Dickinson, P; John, L; Wilkinson, A; Pike, T W

2014-04-01

This paper describes and evaluates a flexible, non-invasive tagging system for the automated identification and long-term monitoring of individual three-spined sticklebacks Gasterosteus aculeatus. The system is based on barcoded tags, which can be reliably and robustly detected and decoded to provide information on an individual's identity and location. Because large numbers of fish can be individually tagged, it can be used to monitor individual- and group-level dynamics within fish shoals. © 2014 The Fisheries Society of the British Isles.

Multimodal evidence of regional midcingulate gray matter volume underlying conflict monitoring

PubMed Central

Parvaz, Muhammad A.; Maloney, Thomas; Moeller, Scott J.; Malaker, Pias; Konova, Anna B.; Alia-Klein, Nelly; Goldstein, Rita Z.

2014-01-01

Functional neuroimaging studies have long implicated the mid-cingulate cortex (MCC) in conflict monitoring, but it is not clear whether its structural integrity (i.e., the gray matter volume) influences its conflict monitoring function. In this multimodal study, we used T1-weighted MRI scans as well as event-related potentials (ERPs) to test whether the MCC gray matter volume is associated with the electrocortical marker (i.e., No-go N200 ERP component) of conflict monitoring in healthy individuals. The specificity of such a relationship in health was determined in two ways: by (A) acquiring the same data from individuals with cocaine use disorder (CUD), known to have deficits in executive function including behavioral monitoring; and (B) acquiring the P300 ERP component that is linked with attention allocation and not specifically with conflict monitoring. Twenty-five (39.1 ± 8.4 years; 8 females) healthy individuals and 25 (42.7 ± 5.9 years; 6 females) individuals with CUD underwent a rewarded Go/No-go task during which the ERP data was collected, and they also underwent a structural MRI scan. The whole brain regression analysis showed a significant correlation between MCC structural integrity and the well-known ERP measure of conflict monitoring (N200, but not the P300) in healthy individuals, which was absent in CUD who were characterized by reduced MCC gray matter volume, N200 abnormalities as well as reduced task accuracy. In individuals with CUD instead, the N200 amplitude was associated with drug addiction symptomatology. These results show that the integrity of MCC volume is directly associated with the electrocortical correlates of conflict monitoring in healthy individuals, and such an association breaks down in psychopathologies that impact these brain processes. Taken together, this MCC–N200 association may serve as a biomarker of improved behavioral monitoring processes in diseased populations. PMID:24918068

Multimodal evidence of regional midcingulate gray matter volume underlying conflict monitoring.

PubMed

Parvaz, Muhammad A; Maloney, Thomas; Moeller, Scott J; Malaker, Pias; Konova, Anna B; Alia-Klein, Nelly; Goldstein, Rita Z

2014-01-01

Functional neuroimaging studies have long implicated the mid-cingulate cortex (MCC) in conflict monitoring, but it is not clear whether its structural integrity (i.e., the gray matter volume) influences its conflict monitoring function. In this multimodal study, we used T1-weighted MRI scans as well as event-related potentials (ERPs) to test whether the MCC gray matter volume is associated with the electrocortical marker (i.e., No-go N200 ERP component) of conflict monitoring in healthy individuals. The specificity of such a relationship in health was determined in two ways: by (A) acquiring the same data from individuals with cocaine use disorder (CUD), known to have deficits in executive function including behavioral monitoring; and (B) acquiring the P300 ERP component that is linked with attention allocation and not specifically with conflict monitoring. Twenty-five (39.1 ± 8.4 years; 8 females) healthy individuals and 25 (42.7 ± 5.9 years; 6 females) individuals with CUD underwent a rewarded Go/No-go task during which the ERP data was collected, and they also underwent a structural MRI scan. The whole brain regression analysis showed a significant correlation between MCC structural integrity and the well-known ERP measure of conflict monitoring (N200, but not the P300) in healthy individuals, which was absent in CUD who were characterized by reduced MCC gray matter volume, N200 abnormalities as well as reduced task accuracy. In individuals with CUD instead, the N200 amplitude was associated with drug addiction symptomatology. These results show that the integrity of MCC volume is directly associated with the electrocortical correlates of conflict monitoring in healthy individuals, and such an association breaks down in psychopathologies that impact these brain processes. Taken together, this MCC-N200 association may serve as a biomarker of improved behavioral monitoring processes in diseased populations.

A Non-Invasive Multichannel Hybrid Fiber-Optic Sensor System for Vital Sign Monitoring

PubMed Central

Fajkus, Marcel; Nedoma, Jan; Martinek, Radek; Vasinek, Vladimir; Nazeran, Homer; Siska, Petr

2017-01-01

In this article, we briefly describe the design, construction, and functional verification of a hybrid multichannel fiber-optic sensor system for basic vital sign monitoring. This sensor uses a novel non-invasive measurement probe based on the fiber Bragg grating (FBG). The probe is composed of two FBGs encapsulated inside a polydimethylsiloxane polymer (PDMS). The PDMS is non-reactive to human skin and resistant to electromagnetic waves, UV absorption, and radiation. We emphasize the construction of the probe to be specifically used for basic vital sign monitoring such as body temperature, respiratory rate and heart rate. The proposed sensor system can continuously process incoming signals from up to 128 individuals. We first present the overall design of this novel multichannel sensor and then elaborate on how it has the potential to simplify vital sign monitoring and consequently improve the comfort level of patients in long-term health care facilities, hospitals and clinics. The reference ECG signal was acquired with the use of standard gel electrodes fixed to the monitored person’s chest using a real-time monitoring system for ECG signals with virtual instrumentation. The outcomes of these experiments have unambiguously proved the functionality of the sensor system and will be used to inform our future research in this fast developing and emerging field. PMID:28075341

Time and number of displays impact critical signal detection in fetal heart rate tracings.

PubMed

Anderson, Brittany L; Scerbo, Mark W; Belfore, Lee A; Abuhamad, Alfred Z

2011-06-01

Interest in centralized monitoring in labor and delivery units is growing because it affords the opportunity to monitor multiple patients simultaneously. However, a long history of research on sustained attention reveals these types of monitoring tasks can be problematic. The goal of the present experiment was to examine the ability of individuals to detect critical signals in fetal heart rate (FHR) tracings in one or more displays over an extended period of time. Seventy-two participants monitored one, two, or four computer-simulated FHR tracings on a computer display for the appearance of late decelerations over a 48-minute vigil. Measures of subjective stress and workload were also obtained before and after the vigil. The results showed that detection accuracy decreased over time and also declined as the number of displays increased. The subjective reports indicated that participants found the task to be stressful and mentally demanding, effortful, and frustrating. The results suggest that centralized monitoring that allows many patients to be monitored simultaneously may impose a detrimental attentional burden on the observer. Furthermore, this seemingly benign task may impose an additional source of stress and mental workload above what is commonly found in labor and delivery units. © Thieme Medical Publishers.

“I Was Relieved to Know That My Baby Was Safe”: Women’s Attitudes and Perceptions on Using a New Electronic Fetal Heart Rate Monitor during Labor in Tanzania

PubMed Central

Rivenes Lafontan, Sara; Sundby, Johanne; Ersdal, Hege L.; Abeid, Muzdalifat; Kidanto, Hussein L.; Mbekenga, Columba K.

2018-01-01

To increase labor monitoring and prevent neonatal morbidity and mortality, a new wireless, strap-on electronic fetal heart rate monitor called Moyo was introduced in Tanzania in 2016. As part of the ongoing evaluation of the introduction of the monitor, the aim of this study was to explore the attitudes and perceptions of women who had worn the monitor continuously during their most recent delivery and perceptions about how it affected care. This knowledge is important to identify barriers towards adaptation in order to introduce new technology more effectively. We carried out 20 semi-structured individual interviews post-labor at two hospitals in Tanzania. A thematic content analysis was used to analyze the data. Our results indicated that the use of the monitor positively affected the women’s birth experience. It provided much-needed reassurance about the wellbeing of the child. The women considered that wearing Moyo improved care due to an increase in communication and attention from birth attendants. However, the women did not fully understand the purpose and function of the device and overestimated its capabilities. This highlights the need to improve how and when information is conveyed to women in labor. PMID:29425167

Monitoring what is real: The effects of modality and action on accuracy and type of reality monitoring error.

PubMed

Garrison, Jane R; Bond, Rebecca; Gibbard, Emma; Johnson, Marcia K; Simons, Jon S

2017-02-01

Reality monitoring refers to processes involved in distinguishing internally generated information from information presented in the external world, an activity thought to be based, in part, on assessment of activated features such as the amount and type of cognitive operations and perceptual content. Impairment in reality monitoring has been implicated in symptoms of mental illness and associated more widely with the occurrence of anomalous perceptions as well as false memories and beliefs. In the present experiment, the cognitive mechanisms of reality monitoring were probed in healthy individuals using a task that investigated the effects of stimulus modality (auditory vs visual) and the type of action undertaken during encoding (thought vs speech) on subsequent source memory. There was reduced source accuracy for auditory stimuli compared with visual, and when encoding was accompanied by thought as opposed to speech, and a greater rate of externalization than internalization errors that was stable across factors. Interpreted within the source monitoring framework (Johnson, Hashtroudi, & Lindsay, 1993), the results are consistent with the greater prevalence of clinically observed auditory than visual reality discrimination failures. The significance of these findings is discussed in light of theories of hallucinations, delusions and confabulation. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déjà vu experiences in healthy subjects are unrelated to laboratory tests of recollection and familiarity for word stimuli.

PubMed

O'Connor, Akira R; Moulin, Chris J A

2013-01-01

Recent neuropsychological and neuroscientific research suggests that people who experience more déjà vu display characteristic patterns in normal recognition memory. We conducted a large individual differences study (n = 206) to test these predictions using recollection and familiarity parameters recovered from a standard memory task. Participants reported déjà vu frequency and a number of its correlates, and completed a recognition memory task analogous to a Remember-Know procedure. The individual difference measures replicated an established correlation between déjà vu frequency and frequency of travel, and recognition performance showed well-established word frequency and accuracy effects. Contrary to predictions, no relationships were found between déjà vu frequency and recollection or familiarity memory parameters from the recognition test. We suggest that déjà vu in the healthy population reflects a mismatch between errant memory signaling and memory monitoring processes not easily characterized by standard recognition memory task performance.

Déjà vu experiences in healthy subjects are unrelated to laboratory tests of recollection and familiarity for word stimuli

PubMed Central

O’Connor, Akira R.; Moulin, Chris J. A.

2013-01-01

Recent neuropsychological and neuroscientific research suggests that people who experience more déjà vu display characteristic patterns in normal recognition memory. We conducted a large individual differences study (n = 206) to test these predictions using recollection and familiarity parameters recovered from a standard memory task. Participants reported déjà vu frequency and a number of its correlates, and completed a recognition memory task analogous to a Remember-Know procedure. The individual difference measures replicated an established correlation between déjà vu frequency and frequency of travel, and recognition performance showed well-established word frequency and accuracy effects. Contrary to predictions, no relationships were found between déjà vu frequency and recollection or familiarity memory parameters from the recognition test. We suggest that déjà vu in the healthy population reflects a mismatch between errant memory signaling and memory monitoring processes not easily characterized by standard recognition memory task performance. PMID:24409159

Neutron beam flux monitors in coaxial and planar geometry for neutron scattering instruments at Dhruva reactor

NASA Astrophysics Data System (ADS)

Desai, Shraddha S.; Devan, Shylaja; Das, Amrita; Patkar, S. M.; Rao, Mala N.

2018-04-01

Neutron scattering instruments at Dhruva reactor are equipped with in house developed neutron beam flux monitors. Measurements of variations in intensity are essential to normalize the scattered neutron spectra against the reactor power fluctuations, energy of monochromatic beam, and various other factors. Two different beam monitor geometries are considered as per the beam size and optics. These detectors are fabricated with tailor-made designs to suit individual beam size and neutron flux. Pencil size beam monitors for integral intensity measurement are fabricated with coaxial geometry and BF3 fill gas for high n-gamma discrimination and count rate capability. Brass cathode design is modified to SS based rugged design, considering beam transmission. Coaxial beam monitor partially intercepts the collimated beam and gives relative magnitude of the flux with time. For certain experiments, size of beam varies due to use of focusing monochromator. Thus a beam monitor with square sensitive region covering entire beam is essential. Multiwire based planar detector for use in transmission mode is designed. Negligible absorption of neutron beam intensity within the detector hardware is ensured. Design of detectors is tailor made for beam geometry. Both these types of beam monitors are fabricated and characterized at G2 beam line and Triple Axis Spectrometer at Dhruva reactor. Performance of detector is suitable for the beam monitoring up to neutron flux ˜ 106 n/cm2/sec. Design aspects and performance details of these beam monitors are mentioned in the paper.

Advances in Grid Computing for the FabrIc for Frontier Experiments Project at Fermialb

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herner, K.; Alba Hernandex, A. F.; Bhat, S.

The FabrIc for Frontier Experiments (FIFE) project is a major initiative within the Fermilab Scientic Computing Division charged with leading the computing model for Fermilab experiments. Work within the FIFE project creates close collaboration between experimenters and computing professionals to serve high-energy physics experiments of diering size, scope, and physics area. The FIFE project has worked to develop common tools for job submission, certicate management, software and reference data distribution through CVMFS repositories, robust data transfer, job monitoring, and databases for project tracking. Since the projects inception the experiments under the FIFE umbrella have signicantly matured, and present an increasinglymore » complex list of requirements to service providers. To meet these requirements, the FIFE project has been involved in transitioning the Fermilab General Purpose Grid cluster to support a partitionable slot model, expanding the resources available to experiments via the Open Science Grid, assisting with commissioning dedicated high-throughput computing resources for individual experiments, supporting the eorts of the HEP Cloud projects to provision a variety of back end resources, including public clouds and high performance computers, and developing rapid onboarding procedures for new experiments and collaborations. The larger demands also require enhanced job monitoring tools, which the project has developed using such tools as ElasticSearch and Grafana. in helping experiments manage their large-scale production work ows. This group in turn requires a structured service to facilitate smooth management of experiment requests, which FIFE provides in the form of the Production Operations Management Service (POMS). POMS is designed to track and manage requests from the FIFE experiments to run particular work ows, and support troubleshooting and triage in case of problems. Recently a new certicate management infrastructure called Distributed Computing Access with Federated Identities (DCAFI) has been put in place that has eliminated our dependence on a Fermilab-specic third-party Certicate Authority service and better accommodates FIFE collaborators without a Fermilab Kerberos account. DCAFI integrates the existing InCommon federated identity infrastructure, CILogon Basic CA, and a MyProxy service using a new general purpose open source tool. We will discuss the general FIFE onboarding strategy, progress in expanding FIFE experiments presence on the Open Science Grid, new tools for job monitoring, the POMS service, and the DCAFI project.« less

Advances in Grid Computing for the Fabric for Frontier Experiments Project at Fermilab

NASA Astrophysics Data System (ADS)

Herner, K.; Alba Hernandez, A. F.; Bhat, S.; Box, D.; Boyd, J.; Di Benedetto, V.; Ding, P.; Dykstra, D.; Fattoruso, M.; Garzoglio, G.; Kirby, M.; Kreymer, A.; Levshina, T.; Mazzacane, A.; Mengel, M.; Mhashilkar, P.; Podstavkov, V.; Retzke, K.; Sharma, N.; Teheran, J.

2017-10-01

The Fabric for Frontier Experiments (FIFE) project is a major initiative within the Fermilab Scientific Computing Division charged with leading the computing model for Fermilab experiments. Work within the FIFE project creates close collaboration between experimenters and computing professionals to serve high-energy physics experiments of differing size, scope, and physics area. The FIFE project has worked to develop common tools for job submission, certificate management, software and reference data distribution through CVMFS repositories, robust data transfer, job monitoring, and databases for project tracking. Since the projects inception the experiments under the FIFE umbrella have significantly matured, and present an increasingly complex list of requirements to service providers. To meet these requirements, the FIFE project has been involved in transitioning the Fermilab General Purpose Grid cluster to support a partitionable slot model, expanding the resources available to experiments via the Open Science Grid, assisting with commissioning dedicated high-throughput computing resources for individual experiments, supporting the efforts of the HEP Cloud projects to provision a variety of back end resources, including public clouds and high performance computers, and developing rapid onboarding procedures for new experiments and collaborations. The larger demands also require enhanced job monitoring tools, which the project has developed using such tools as ElasticSearch and Grafana. in helping experiments manage their large-scale production workflows. This group in turn requires a structured service to facilitate smooth management of experiment requests, which FIFE provides in the form of the Production Operations Management Service (POMS). POMS is designed to track and manage requests from the FIFE experiments to run particular workflows, and support troubleshooting and triage in case of problems. Recently a new certificate management infrastructure called Distributed Computing Access with Federated Identities (DCAFI) has been put in place that has eliminated our dependence on a Fermilab-specific third-party Certificate Authority service and better accommodates FIFE collaborators without a Fermilab Kerberos account. DCAFI integrates the existing InCommon federated identity infrastructure, CILogon Basic CA, and a MyProxy service using a new general purpose open source tool. We will discuss the general FIFE onboarding strategy, progress in expanding FIFE experiments presence on the Open Science Grid, new tools for job monitoring, the POMS service, and the DCAFI project.

A versatile miniature bioreactor and its application to bioelectrochemistry studies.

PubMed

Kloke, A; Rubenwolf, S; Bücking, C; Gescher, J; Kerzenmacher, S; Zengerle, R; von Stetten, F

2010-08-15

Often, reproducible investigations on bio-microsystems essentially require a flexible but well-defined experimental setup, which in its features corresponds to a bioreactor. We therefore developed a miniature bioreactor with a volume in the range of a few millilitre that is assembled by alternate stacking of individual polycarbonate elements and silicone gaskets. All the necessary supply pipes are incorporated as bore holes or cavities within the individual elements. Their combination allows for a bioreactor assembly that is easily adaptable in size and functionality to experimental demands. It allows for controlling oxygen transfer as well as the monitoring of dissolved oxygen concentration and pH-value. The system provides access for media exchange or sterile sampling. A mass transfer coefficient for oxygen (k(L)a) of 4.3x10(-3) s(-1) at a flow rate of only 15 ml min(-1) and a mixing time of 1.5s at a flow rate of 11 ml min(-1) were observed for the modular bioreactor. Single reactor chambers can be interconnected via ion-conductive membranes to form a two-chamber test setup for investigations on electrochemical systems such as fuel cells or sensors. The versatile applicability of this modular and flexible bioreactor was demonstrated by recording a growth curve of Escherichia coli (including monitoring of pH and oxygen) saturation, and also as by two bioelectrochemical experiments. In the first electrochemical experiment the use of the bioreactor enabled a direct comparison of electrode materials for a laccase-catalyzed oxygen reduction electrode. In a second experiment, the bioreactor was utilized to characterize the influence of outer membrane cytochromes on the performance of Shewanella oneidensis in a microbial fuel cell. Copyright 2010 Elsevier B.V. All rights reserved.

Dynamics of parasitemia of malaria parasites in a naturally and experimentally infected migratory songbird, the great reed warbler Acrocephalus arundinaceus.

PubMed

Zehtindjiev, Pavel; Ilieva, Mihaela; Westerdahl, Helena; Hansson, Bengt; Valkiūnas, Gediminas; Bensch, Staffan

2008-05-01

Little is known about the development of infection of malaria parasites of the genus Plasmodium in wild birds. We used qPCR, targeting specific mitochondrial lineages of Plasmodium ashfordi (GRW2) and Plasmodium relictum (GRW4), to monitor changes in intensities of parasitemia in captive great reed warblers Acrocephalus arundinaceus from summer to spring. The study involved both naturally infected adults and experimentally infected juveniles. The experiment demonstrated that P. ashfordi and P. relictum lineages differ substantially in several life-history traits (e.g. prepatent period and dynamics of parasitemia) and that individual hosts show substantial differences in responses to these infections. The intensity of parasitemia of lineages in mixed infections co-varied positively, suggesting a control mechanism by the host that is general across the parasite lineages. The intensity of parasitemia for individual hosts was highly repeatable suggesting variation between the host individuals in their genetic or acquired control of the infections. In future studies, care must be taken to avoid mixed infections in wild caught donors, and when possible use mosquitoes for the experiments as inoculation of infectious blood ignores important initial stages of the contact between the bird and the parasite.

A Distributed Computing Framework for Real-Time Detection of Stress and of Its Propagation in a Team.

PubMed

Pandey, Parul; Lee, Eun Kyung; Pompili, Dario

2016-11-01

Stress is one of the key factor that impacts the quality of our daily life: From the productivity and efficiency in the production processes to the ability of (civilian and military) individuals in making rational decisions. Also, stress can propagate from one individual to other working in a close proximity or toward a common goal, e.g., in a military operation or workforce. Real-time assessment of the stress of individuals alone is, however, not sufficient, as understanding its source and direction in which it propagates in a group of people is equally-if not more-important. A continuous near real-time in situ personal stress monitoring system to quantify level of stress of individuals and its direction of propagation in a team is envisioned. However, stress monitoring of an individual via his/her mobile device may not always be possible for extended periods of time due to limited battery capacity of these devices. To overcome this challenge a novel distributed mobile computing framework is proposed to organize the resources in the vicinity and form a mobile device cloud that enables offloading of computation tasks in stress detection algorithm from resource constrained devices (low residual battery, limited CPU cycles) to resource rich devices. Our framework also supports computing parallelization and workflows, defining how the data and tasks divided/assigned among the entities of the framework are designed. The direction of propagation and magnitude of influence of stress in a group of individuals are studied by applying real-time, in situ analysis of Granger Causality. Tangible benefits (in terms of energy expenditure and execution time) of the proposed framework in comparison to a centralized framework are presented via thorough simulations and real experiments.

Validation of Individual-Based Markov-Like Stochastic Process Model of Insect Behavior and a “Virtual Farm” Concept for Enhancement of Site-Specific IPM

PubMed Central

Lux, Slawomir A.; Wnuk, Andrzej; Vogt, Heidrun; Belien, Tim; Spornberger, Andreas; Studnicki, Marcin

2016-01-01

The paper reports application of a Markov-like stochastic process agent-based model and a “virtual farm” concept for enhancement of site-specific Integrated Pest Management. Conceptually, the model represents a “bottom-up ethological” approach and emulates behavior of the “primary IPM actors”—large cohorts of individual insects—within seasonally changing mosaics of spatiotemporally complex faming landscape, under the challenge of the local IPM actions. Algorithms of the proprietary PESTonFARM model were adjusted to reflect behavior and ecology of R. cerasi. Model parametrization was based on compiled published information about R. cerasi and the results of auxiliary on-farm experiments. The experiments were conducted on sweet cherry farms located in Austria, Germany, and Belgium. For each farm, a customized model-module was prepared, reflecting its spatiotemporal features. Historical data about pest monitoring, IPM treatments and fruit infestation were used to specify the model assumptions and calibrate it further. Finally, for each of the farms, virtual IPM experiments were simulated and the model-generated results were compared with the results of the real experiments conducted on the same farms. Implications of the findings for broader applicability of the model and the “virtual farm” approach—were discussed. PMID:27602000

Validation of Individual-Based Markov-Like Stochastic Process Model of Insect Behavior and a "Virtual Farm" Concept for Enhancement of Site-Specific IPM.

PubMed

Lux, Slawomir A; Wnuk, Andrzej; Vogt, Heidrun; Belien, Tim; Spornberger, Andreas; Studnicki, Marcin

2016-01-01

The paper reports application of a Markov-like stochastic process agent-based model and a "virtual farm" concept for enhancement of site-specific Integrated Pest Management. Conceptually, the model represents a "bottom-up ethological" approach and emulates behavior of the "primary IPM actors"-large cohorts of individual insects-within seasonally changing mosaics of spatiotemporally complex faming landscape, under the challenge of the local IPM actions. Algorithms of the proprietary PESTonFARM model were adjusted to reflect behavior and ecology of R. cerasi. Model parametrization was based on compiled published information about R. cerasi and the results of auxiliary on-farm experiments. The experiments were conducted on sweet cherry farms located in Austria, Germany, and Belgium. For each farm, a customized model-module was prepared, reflecting its spatiotemporal features. Historical data about pest monitoring, IPM treatments and fruit infestation were used to specify the model assumptions and calibrate it further. Finally, for each of the farms, virtual IPM experiments were simulated and the model-generated results were compared with the results of the real experiments conducted on the same farms. Implications of the findings for broader applicability of the model and the "virtual farm" approach-were discussed.

Customizable scientific web-portal for DIII-D nuclear fusion experiment

NASA Astrophysics Data System (ADS)

Abla, G.; Kim, E. N.; Schissel, D. P.

2010-04-01

Increasing utilization of the Internet and convenient web technologies has made the web-portal a major application interface for remote participation and control of scientific instruments. While web-portals have provided a centralized gateway for multiple computational services, the amount of visual output often is overwhelming due to the high volume of data generated by complex scientific instruments and experiments. Since each scientist may have different priorities and areas of interest in the experiment, filtering and organizing information based on the individual user's need can increase the usability and efficiency of a web-portal. DIII-D is the largest magnetic nuclear fusion device in the US. A web-portal has been designed to support the experimental activities of DIII-D researchers worldwide. It offers a customizable interface with personalized page layouts and list of services for users to select. Each individual user can create a unique working environment to fit his own needs and interests. Customizable services are: real-time experiment status monitoring, diagnostic data access, interactive data analysis and visualization. The web-portal also supports interactive collaborations by providing collaborative logbook, and online instant announcement services. The DIII-D web-portal development utilizes multi-tier software architecture, and Web 2.0 technologies and tools, such as AJAX and Django, to develop a highly-interactive and customizable user interface.

40 CFR 141.562 - My system only has two or fewer filters-is there any special provision regarding individual...

Code of Federal Regulations, 2012 CFR

2012-07-01

... filters-is there any special provision regarding individual filter turbidity monitoring? 141.562 Section... Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.562 My system only has two or fewer filters—is there any special provision regarding individual filter turbidity monitoring? Yes, if...

40 CFR 141.562 - My system only has two or fewer filters-is there any special provision regarding individual...

Code of Federal Regulations, 2014 CFR

2014-07-01

... filters-is there any special provision regarding individual filter turbidity monitoring? 141.562 Section... Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.562 My system only has two or fewer filters—is there any special provision regarding individual filter turbidity monitoring? Yes, if...

40 CFR 141.562 - My system only has two or fewer filters-is there any special provision regarding individual...

Code of Federal Regulations, 2010 CFR

2010-07-01

... filters-is there any special provision regarding individual filter turbidity monitoring? 141.562 Section... Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.562 My system only has two or fewer filters—is there any special provision regarding individual filter turbidity monitoring? Yes, if...

40 CFR 141.562 - My system only has two or fewer filters-is there any special provision regarding individual...

Code of Federal Regulations, 2011 CFR

2011-07-01

... filters-is there any special provision regarding individual filter turbidity monitoring? 141.562 Section... Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.562 My system only has two or fewer filters—is there any special provision regarding individual filter turbidity monitoring? Yes, if...

40 CFR 141.562 - My system only has two or fewer filters-is there any special provision regarding individual...

Code of Federal Regulations, 2013 CFR

2013-07-01

... filters-is there any special provision regarding individual filter turbidity monitoring? 141.562 Section... Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.562 My system only has two or fewer filters—is there any special provision regarding individual filter turbidity monitoring? Yes, if...

Fast energy spectrum and transverse beam profile monitoring and feedback systems for the SLC linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soderstrom, E.J.; Abrams, G.S.; Weinstein, A.J.

Fast energy spectrum and transverse beam profile monitoring systems have been tested at the SLC. The signals for each system are derived from digitizations of images on phosphor screens. Individual beam bunch images are digitized in the case of the transverse profile system and synchrotron radiation images produced by wiggler magnets for the energy spectrum. Measurements are taken at two-second intervals. Feedback elements have been installed for future use and consist of rf phase shifters to control energy spectrum and dipole correctors to control the beam launch into the linac affecting the transverse beam profile. Details of these systems, includingmore » hardware, timing, data acquisition, data reduction, measurement accuracy, and operational experience will be presented. 9 refs.« less

The Cubesat Heliospheric Imaging Experiment for Space Weather Prediction

NASA Astrophysics Data System (ADS)

DeForest, Craig; Howard, T.; Dickinson, J.; Epperly, M.; Kief, C.

2010-05-01

Heliospheric imaging data have been shown to improve space weather prediction by an order of magnitude, and heliospheric monitoring by the SMEI and STEREO-HI instruments have proven to be extremely useful for understanding heliospheric conditions near Earth. However, SMEI is approaching end-of-life and the STEREOs are drifting away from favorable Earth-viewing geometry just as the new solar cycle begins. CHIME is an innovative, miniaturized, fully functional space weather heliospheric monitor that fits within the 3U CubeSat envelope and can be flown individually (as a scientific or demonstrator mission) or in a swarm (to attain operational-class reliability) at a small fraction of the cost of a conventional mission. Here we describe the CHIME concept and its use with the automated processing pipeline AICMED to improve space weather prediction.

Developing and Monitoring Individual Education Plans for Handicapped Children.

ERIC Educational Resources Information Center

Armstrong, Mary Lee

The practicum was designed to develop, implement, monitor, and evaluate a management system for developing and monitoring individual education plans (IEPs) for handicapped children as mandated by P.L. 94-142, the Education for All Handicapped Children Act. The products included an expectancy formula for educable mentally retarded (EMR) and…

Tolerant indirect reciprocity can boost social welfare through solidarity with unconditional cooperators in private monitoring.

PubMed

Okada, Isamu; Sasaki, Tatsuya; Nakai, Yutaka

2017-08-29

Indirect reciprocity is an important mechanism for resolving social dilemmas. Previous studies explore several types of assessment rules that are evolutionarily stable for keeping cooperation regimes. However, little is known about the effects of private information on social systems. Most indirect reciprocity studies assume public monitoring in which individuals share a single assessment for each individual. Here, we consider a private monitoring system that loosens such an unnatural assumption. We explore the stable norms in the private system using an individual-based simulation. We have three main findings. First, narrow and unstable cooperation: cooperation in private monitoring becomes unstable and the restricted norms cannot maintain cooperative regimes while they can in public monitoring. Second, stable coexistence of discriminators and unconditional cooperators: under private monitoring, unconditional cooperation can play a role in keeping a high level of cooperation in tolerant norm situations. Finally, Pareto improvement: private monitoring can achieve a higher cooperation rate than does public monitoring.

Macro and micro structures in the dorsal anterior cingulate cortex contribute to individual differences in self-monitoring.

PubMed

Yang, Junyi; Tian, Xue; Wei, Dongtao; Liu, Huijuan; Zhang, Qinglin; Wang, Kangcheng; Chen, Qunlin; Qiu, Jiang

2016-06-01

Individual differences in self-monitoring, which are the capability to adjust behavior to adapt to social situations, influence a wide range of social behaviors. However, understanding of focal differences in brain structures related to individual self-monitoring is minimal, particularly when micro and macro structures are considered simultaneously. The present study investigates the relationship between self-monitoring and brain structure in a relatively large sample of young adults. Voxel-based morphometry (VBM) revealed a significant positive correlation between self-monitoring and gray matter volume in the dorsal cingulate anterior cortex (dACC), dorsal lateral prefrontal cortex (DLPFC), and bilateral ventral striatum (VS). Further analysis revealed a significant negative correlation between self-monitoring and white matter (WM) integrity, as indexed by fractional anisotropy (FA) in the anterior cingulum (ACG) bundle. Moreover, there was a significant positive correlation between self-monitoring and mean radius diffusion (RD). These results shed light on the structural neural basis of variation in self-monitoring.

Population cage experiments with a vertebrate: The temporal demography and cytonuclear genetics of hybridization on Gambusia fishes

USGS Publications Warehouse

Scribner, Kim T.; Avise, John C.

1994-01-01

The dynamics of mitochondrial and multilocus nuclear genotypic frequencies were monitored for 2 yr in experimental populations established with equal numbers of two poeciliid fishes (Gambusia affinis and Gambusia holbrooki) that hybridize naturally in the southeastern United States. In replicated "small-pool" populations (experiment I), 1018 sampled individuals at six time periods revealed an initial flush of hybridization, followed by a rapid decline in frequencies of G. affinis nuclear and mitochondrial alleles over 64 wk. Decay of gametic and cytonuclear disequilibria differed from expectations under random mating as well as under a model of assortative mating involving empirically estimated mating propensities. In two replicate "large-pond" populations (experiment II), 841 sampled individuals across four reproductive cohorts revealed lower initial frequencies of F1 hybrids than in experiment I, but again G. holbrooki alleles achieved high frequencies over four generations (72 wk). Thus, evolution within experimental Gambusia hybrid populations can be extremely rapid, resulting in consistent loss of G. affinis nuclear and cytoplasmic alleles. Concordance in results between experiments and across genetic markers suggests strong directional selection favoring G. holbrooki genotypes. Results are interpreted in light of previous reports of genotype-specific differences in life-history traits, reproductive ecology, patterns of recruitment, and size-specific mortality, and in the context of patterns of introgression previously studied indirectly from spatial observations on cytonuclear genotypes in natural Gambusia populations.

Identifying Indices of Happiness and Unhappiness Among Adults With Autism: Potential Targets for Behavioral Assessment and Intervention

PubMed Central

Parsons, Marsha B; Bentley, Erik; Inman, Amy; Lattimore, L. Perry

2012-01-01

Research is increasingly demonstrating the importance of monitoring indices of happiness as part of behavioral programs for individuals who have severe intellectual disabilities. We evaluated a practitioner-oriented process for identifying and validating individualized indices of this private event among three adults with autism who were nonvocal or minimally vocal. Caregiver surveys were administered to obtain agreement regarding behavior displayed when the individuals were happy and unhappy, as well as situations in which they were likely to experience happiness and unhappiness. Observations corroborated caregiver opinion in that participants displayed more happiness indices in situations reported to be accompanied by happiness, and for the most part, more unhappiness indices in reported unhappiness situations. Subsequent choices by each participant supported the validity of the individualized indices. Results are discussed regarding how identifying happiness indices can be a useful component of behavioral applications, as well as guidelines and cautions regarding use of the indices in routine practice. PMID:23326627

Applying contact to individual silicon nanowires using a dielectrophoresis (DEP)-based technique

NASA Astrophysics Data System (ADS)

Leiterer, Christian; Broenstrup, Gerald; Jahr, Norbert; Urban, Matthias; Arnold, Cornelia; Christiansen, Silke; Fritzsche, Wolfgang

2013-05-01

One major challenge for the technological use of nanostructures is the control of their electrical and optoelectronic properties. For that purpose, extensive research into the electrical characterization and therefore a fast and reliable way of contacting these structures are needed. Here, we report on a new, dielectrophoresis (DEP)-based technique, which enables to apply sufficient and reliable contact to individual nanostructures, like semiconducting nanowires (NW), easily and without the need for lithography. The DEP contacting technique presented in this article can be done without high-tech equipment and monitored in situ with an optical microscope. In the presented experiments, individual SiNWs are trapped and subsequently welded between two photolithographically pre-patterned electrodes by applying varying AC voltages to the electrodes. To proof the quality of these contacts, I-V curves, photoresponse and photoconductivity of a single SiNW were measured. Furthermore, the measured photoconductivity in dependence on the wavelength of illuminated light and was compared with calculations predicting the absorption spectra of an individual SiNW.

The Hydrological Open Air Laboratory (HOAL) in Petzenkirchen: a hypothesis-driven observatory

NASA Astrophysics Data System (ADS)

Blöschl, G.; Blaschke, A. P.; Broer, M.; Bucher, C.; Carr, G.; Chen, X.; Eder, A.; Exner-Kittridge, M.; Farnleitner, A.; Flores-Orozco, A.; Haas, P.; Hogan, P.; Kazemi Amiri, A.; Oismüller, M.; Parajka, J.; Silasari, R.; Stadler, P.; Strauss, P.; Vreugdenhil, M.; Wagner, W.; Zessner, M.

2016-01-01

Hydrological observatories bear a lot of resemblance to the more traditional research catchment concept, but tend to differ in providing more long-term facilities that transcend the lifetime of individual projects, are more strongly geared towards performing interdisciplinary research, and are often designed as networks to assist in performing collaborative science. This paper illustrates how the experimental and monitoring set-up of an observatory, the 66 ha Hydrological Open Air Laboratory (HOAL) in Petzenkirchen, Lower Austria, has been established in a way that allows meaningful hypothesis testing. The overarching science questions guided site selection, identification of dissertation topics and the base monitoring. The specific hypotheses guided the dedicated monitoring and sampling, individual experiments, and repeated experiments with controlled boundary conditions. The purpose of the HOAL is to advance the understanding of water-related flow and transport processes involving sediments, nutrients and microbes in small catchments. The HOAL catchment is ideally suited for this purpose, because it features a range of different runoff generation processes (surface runoff, springs, tile drains, wetlands), the nutrient inputs are known, and it is convenient from a logistic point of view as all instruments can be connected to the power grid and a high-speed glassfibre local area network (LAN). The multitude of runoff generation mechanisms in the catchment provides a genuine laboratory where hypotheses of flow and transport can be tested, either by controlled experiments or by contrasting sub-regions of different characteristics. This diversity also ensures that the HOAL is representative of a range of catchments around the world, and the specific process findings from the HOAL are applicable to a variety of agricultural catchment settings. The HOAL is operated jointly by the Vienna University of Technology and the Federal Agency for Water Management and takes advantage of the Vienna Doctoral Programme on Water Resource Systems funded by the Austrian Science Funds. The paper presents the science strategy of the set-up of the observatory, discusses the implementation of the HOAL, gives examples of the hypothesis testing and summarises the lessons learned. The paper concludes with an outlook on future developments.

The Hydrological Open Air Laboratory (HOAL) in Petzenkirchen: a hypotheses driven observatory

NASA Astrophysics Data System (ADS)

Blöschl, G.; Blaschke, A. P.; Broer, M.; Bucher, C.; Carr, G.; Chen, X.; Eder, A.; Exner-Kittridge, M.; Farnleitner, A.; Flores-Orozco, A.; Haas, P.; Hogan, P.; Kazemi Amiri, A.; Oismüller, M.; Parajka, J.; Silasari, R.; Stadler, P.; Strauß, P.; Vreugdenhil, M.; Wagner, W.; Zessner, M.

2015-07-01

Hydrological observatories bear a lot of resemblance to the more traditional research catchment concept but tend to differ in providing more long term facilities that transcend the lifetime of individual projects, are more strongly geared towards performing interdisciplinary research, and are often designed as networks to assist in performing collaborative science. This paper illustrates how the experimental and monitoring setup of an observatory, the 66 ha Hydrological Open Air Laboratory (HOAL) in Petzenkirchen, Lower Austria, has been established in a way that allows meaningful hypothesis testing. The overarching science questions guided site selection, identifying dissertation topics and the base monitoring. The specific hypotheses guided the dedicated monitoring and sampling, individual experiments, and repeated experiments with controlled boundary conditions. The purpose of the HOAL is to advance the understanding of water related flow and transport processes involving sediments, nutrients and microbes in small catchments. The HOAL catchment is ideally suited for this purpose, because it features a range of different runoff generation processes (surface runoff, springs, tile drains, wetlands), the nutrient inputs are known, and it is convenient from a logistic point of view as all instruments can be connected to the power grid and a high speed glassfibre Local Area Network. The multitude of runoff generation mechanisms in the catchment provide a genuine laboratory where hypotheses of flow and transport can be tested, either by controlled experiments or by contrasting sub-regions of different characteristics. This diversity also ensures that the HOAL is representative of a range of catchments around the world and the specific process findings from the HOAL are applicable to a variety of agricultural catchment settings. The HOAL is operated jointly by the Vienna University of Technology and the Federal Agency for Water Management and takes advantage of the Vienna Doctoral Programme on Water Resource Systems funded by the Austrian Science Funds. The paper presents the science strategy of the setup of the observatory, discusses the implementation of the HOAL, gives examples of the hypothesis testing and summarises the lessons learned. The paper concludes with an outlook on future developments.

Grapheme-color synesthesia influences overt visual attention.

PubMed

Carriere, Jonathan S A; Eaton, Daniel; Reynolds, Michael G; Dixon, Mike J; Smilek, Daniel

2009-02-01

For individuals with grapheme-color synesthesia, achromatic letters and digits elicit vivid perceptual experiences of color. We report two experiments that evaluate whether synesthesia influences overt visual attention. In these experiments, two grapheme-color synesthetes viewed colored letters while their eye movements were monitored. Letters were presented in colors that were either congruent or incongruent with the synesthetes' colors. Eye tracking analysis showed that synesthetes exhibited a color congruity bias-a propensity to fixate congruently colored letters more often and for longer durations than incongruently colored letters-in a naturalistic free-viewing task. In a more structured visual search task, this congruity bias caused synesthetes to rapidly fixate and identify congruently colored target letters, but led to problems in identifying incongruently colored target letters. The results are discussed in terms of their implications for perception in synesthesia.

Optimization of Surveys with Internet Operated Deep-sea Crawlers, as an Integrated Tool for Ocean Cabled Observatories: Monitoring the Benthic Community of a Methane Hydrates Site in Barkley Canyon (BC, Canada)

NASA Astrophysics Data System (ADS)

Chatzievangelou, D.; Suarez, A.; Aguzzi, J.; Bigham, K.; Thomsen, L.

2017-12-01

Deep-sea research is entering an era of coordinated, multidisciplinary monitoring of benthic ecosystems, from local and regional to global scale. Technological advances, such as the development of ocean cabled observatories and mobile vehicles operating within them, raise the issue of "smart" study designs. The objective is optimizing the balance among reduced effort (i.e. sampling, data transfer and storage, a posteriori treatment), accurate representation of the monitored ecosystems and a minimal ecological footprint. For this study, 18 linear imaging transects ( 25 m each, 1 Hz frequency) were performed by the Internet Operated Deep-sea Crawler "Wally" at the Barkley Canyon hydrates site (870 m depth) within the Ocean Networks Canada NEPTUNE observatory, generating a total of 19920 images. In order to evaluate sampling effort, species accumulation curves were calculated against the number of transects, and the permanence time of mobile individuals in the crawler's field of view was used to assess the number of individuals captured for different potential imaging frequencies. The effect of the crawler caterpillars on benthic organisms was evaluated by comparing the images of disturbed (i.e previous tracks) vs. undisturbed seabed. The analyses showed that maximum species richness (i.e. 18 species) was achieved after 10 transects, while 0.33 Hz and 0.5 Hz imaging frequencies captured more than 95% of the individuals counted with the original 1 Hz method. Preliminary results indicate no differences in the numbers of benthic animals between the disturbed and the undisturbed seabed parts. These findings allow the design of future experiments under similar conditions with minimized costs and effort without compromising data quality. Finally, the low invasiveness of the crawler as a monitoring platform, as long as certain protocols are followed, is highlighted. Ongoing analyses of the same transects assess the varying macro- and megafauna, in relation to the distance from a nearby, small ( 2-3 m high) hydrate mound.

The effects of initial testing on false recall and false recognition in the social contagion of memory paradigm.

PubMed

Huff, Mark J; Davis, Sara D; Meade, Michelle L

2013-08-01

In three experiments, participants studied photographs of common household scenes. Following study, participants completed a category-cued recall test without feedback (Exps. 1 and 3), a category-cued recall test with feedback (Exp. 2), or a filler task (no-test condition). Participants then viewed recall tests from fictitious previous participants that contained erroneous items presented either one or four times, and then completed final recall and source recognition tests. The participants in all conditions reported incorrect items during final testing (a social contagion effect), and across experiments, initial testing had no impact on false recall of erroneous items. However, on the final source-monitoring recognition test, initial testing had a protective effect against false source recognition: Participants who were initially tested with and without feedback on category-cued initial tests attributed fewer incorrect items to the original event on the final source-monitoring recognition test than did participants who were not initially tested. These data demonstrate that initial testing may protect individuals' memories from erroneous suggestions.

The role of metacognition in prospective memory: anticipated task demands influence attention allocation strategies.

PubMed

Rummel, Jan; Meiser, Thorsten

2013-09-01

The present study investigates how individuals distribute their attentional resources between a prospective memory task and an ongoing task. Therefore, metacognitive expectations about the attentional demands of the prospective-memory task were manipulated while the factual demands were held constant. In Experiments 1a and 1b, we found attentional costs from a prospective-memory task with low factual demands to be significantly reduced when information about the low to-be-expected demands were provided, while prospective-memory performance remained largely unaffected. In Experiment 2, attentional monitoring in a more demanding prospective-memory task also varied with information about the to-be-expected demands (high vs. low) and again there were no equivalent changes in prospective-memory performance. These findings suggest that attention-allocation strategies of prospective memory rely on metacognitive expectations about prospective-memory task demands. Furthermore, the results suggest that attentional monitoring is only functional for prospective memory to the extent to which anticipated task demands reflect objective task demands. Copyright © 2013 Elsevier Inc. All rights reserved.

First attempt of at-cavity cryogenic X-ray detection in a CEBAF cryomodule for field emission monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geng, Rongli; Daly, Edward; Drury, Michael

2015-09-01

We report on the first result of at-cavity X-ray detection in a CEBAF cryomodule for field emission monitoring. In the 8-cavity cryomodule F100, two silicon diodes were installed near the end flange of each cavity. Each cavity was individually tested during the cryomodule test in JLab’s cryomodule test facility. The behaviors of these at-cavity cryogenic X-ray detectors were compared with those of the standard ‘in air’ Geiger-Muller (G-M) tubes. Our initial experiments establish correlation between X-ray response of near diodes and the field emission source cavity in the 8-cavity string. For two out of these eight cavities, we also carriedmore » out at-cavity X-ray detection experiment during their vertical testing. The aim is to track field emission behavior uniquely from vertical cavity testing to horizontal cavity testing in the cryomodule. These preliminary results confirmed our expectation and warrant further effort toward the establishment of permanent at-cavity cryogenic X-ray detection for SRF development and operation.« less

A description of nurses' decision-making in managing electrocardiographic monitor alarms.

PubMed

Gazarian, Priscilla K; Carrier, Natalie; Cohen, Rachel; Schram, Haley; Shiromani, Samara

2015-01-01

To describe the cues and factors that nurses use in their decision-making when responding to clinical alarms. Alarms are designed to be very sensitive, and as a result, they are not very specific. Lack of adherence to the practice standards for electrocardiographic monitoring in hospital settings has been observed, resulting in overuse of the electrocardiographic monitoring. Monitoring without consideration of clinical indicators uses scarce healthcare resources and may even produce untoward circumstances because of alarm fatigue. With so many false alarms, alarm fatigue represents a symptom of a larger problem. It cannot be fixed until all of the factors that contribute to its existence have been examined. This was a qualitative descriptive study. This study was conducted at an academic medical centre located in the Northeast United States. Eight participants were enrolled using purposive sampling. Nurses were observed for two three-hour periods. Following each observation, the nurse was interviewed using the critical decision method to describe the cognitive processes related to the alarm activities. Qualitative data from the conducted interviews were analysed via an a priori framework founded in the critical decision method. This study reveals information, experience, guidance and decision-making as the four prominent categories contributing to nurses' decision-making in relation to alarm management. Managing technology was a category not identified a priori that emerged in the data analysis. Nurses revealed a breadth of information needed to adequately identify and interpret monitor alarms, and how they used that information to put the alarms into the particular context of an individual patient's situations. Understanding the cues and factors nurses use when responding to cardiac alarms will guide the development of learning experiences and inform policies to guide practice. © 2014 John Wiley & Sons Ltd.

Informing the Design of "Lifestyle Monitoring" Technology for the Detection of Health Deterioration in Long-Term Conditions: A Qualitative Study of People Living With Heart Failure.

PubMed

Hargreaves, Sarah; Hawley, Mark S; Haywood, Annette; Enderby, Pamela M

2017-06-28

Health technologies are being developed to help people living at home manage long-term conditions. One such technology is "lifestyle monitoring" (LM), a telecare technology based on the idea that home activities may be monitored unobtrusively via sensors to give an indication of changes in health-state. However, questions remain about LM technology: how home activities change when participants experience differing health-states; and how sensors might capture clinically important changes to inform timely interventions. The objective of this paper was to report the findings of a study aimed at identifying changes in activity indicative of important changes in health in people with long-term conditions, particularly changes indicative of exacerbation, by exploring the relationship between home activities and health among people with heart failure (HF). We aimed to add to the knowledge base informing the development of home monitoring technologies designed to detect health deterioration in order to facilitate early intervention and avoid hospital admissions. This qualitative study utilized semistructured interviews to explore everyday activities undertaken during the three health-states of HF: normal days, bad days, and exacerbations. Potential recruits were identified by specialist nurses and attendees at an HF support group. The sample was purposively selected to include a range of experience of living with HF. The sample comprised a total of 20 people with HF aged 50 years and above, and 11 spouses or partners of the individuals with HF. All resided in Northern England. Participant accounts revealed that home activities are in part shaped by the degree of intrusion from HF symptoms. During an exacerbation, participants undertook activities specifically to ease symptoms, and detailed activity changes were identified. Everyday activity was also influenced by a range of factors other than health. The study highlights the importance of careful development of LM technology to identify changes in activities that occur during clinically important changes in health. These detailed activity changes need to be considered by developers of LM sensors, platforms, and algorithms intended to detect early signs of deterioration. Results suggest that for LM to move forward, sensor set-up should be personalized to individual circumstances and targeted at individual health conditions. LM needs to take account of the uncertainties that arise from placing technology within the home, in order to inform sensor set-up and data interpretation. This targeted approach is likely to yield more clinically meaningful data and address some of the ethical issues of remote monitoring. ©Sarah Hargreaves, Mark S Hawley, Annette Haywood, Pamela M Enderby. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 28.06.2017.

Development of display design and command usage guidelines for Spacelab experiment computer applications

NASA Technical Reports Server (NTRS)

Dodson, D. W.; Shields, N. L., Jr.

1979-01-01

Individual Spacelab experiments are responsible for developing their CRT display formats and interactive command scenarios for payload crew monitoring and control of experiment operations via the Spacelab Data Display System (DDS). In order to enhance crew training and flight operations, it was important to establish some standardization of the crew/experiment interface among different experiments by providing standard methods and techniques for data presentation and experiment commanding via the DDS. In order to establish optimum usage guidelines for the Spacelab DDS, the capabilities and limitations of the hardware and Experiment Computer Operating System design had to be considered. Since the operating system software and hardware design had already been established, the Display and Command Usage Guidelines were constrained to the capabilities of the existing system design. Empirical evaluations were conducted on a DDS simulator to determine optimum operator/system interface utilization of the system capabilities. Display parameters such as information location, display density, data organization, status presentation and dynamic update effects were evaluated in terms of response times and error rates.

40 CFR 141.175 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Systems must maintain the results of individual filter monitoring taken under § 141.174 for at least three years. Systems must report that they have conducted individual filter turbidity monitoring under § 141... report individual filter turbidity measurement results taken under § 141.174 within 10 days after the end...

40 CFR 141.175 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Systems must maintain the results of individual filter monitoring taken under § 141.174 for at least three years. Systems must report that they have conducted individual filter turbidity monitoring under § 141... report individual filter turbidity measurement results taken under § 141.174 within 10 days after the end...

40 CFR 141.175 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Systems must maintain the results of individual filter monitoring taken under § 141.174 for at least three years. Systems must report that they have conducted individual filter turbidity monitoring under § 141... report individual filter turbidity measurement results taken under § 141.174 within 10 days after the end...

40 CFR 141.175 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Systems must maintain the results of individual filter monitoring taken under § 141.174 for at least three years. Systems must report that they have conducted individual filter turbidity monitoring under § 141... report individual filter turbidity measurement results taken under § 141.174 within 10 days after the end...

40 CFR 141.175 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Systems must maintain the results of individual filter monitoring taken under § 141.174 for at least three years. Systems must report that they have conducted individual filter turbidity monitoring under § 141... report individual filter turbidity measurement results taken under § 141.174 within 10 days after the end...

Maintaining activity engagement: individual differences in the process of self-regulating motivation.

PubMed

Sansone, Carol; Thoman, Dustin B

2006-12-01

Typically, models of self-regulation include motivation in terms of goals. Motivation is proposed to differ among individuals as a consequence of the goals they hold as well as how much they value those goals and expect to attain them. We suggest that goal-defined motivation is only one source of motivation critical for sustained engagement. A second source is the motivation that arises from the degree of interest experienced in the process of goal pursuit. Our model integrates both sources of motivation within the goal-striving process and suggests that individuals may actively monitor and regulate them. Conceptualizing motivation in terms of a self-regulatory process provides an organizing framework for understanding how individuals might differ in whether they experience interest while working toward goals, whether they persist without interest, and whether and how they try to create interest. We first present the self-regulation of motivation model and then review research illustrating how the consideration of individual differences at different points in the process allows a better understanding of variability in people's choices, efforts, and persistence over time.

Operating Experience Review of the INL HTE Gas Monitoring System

DOE Office of Scientific and Technical Information (OSTI.GOV)

L. C. Cadwallader; K. G. DeWall

2010-06-01

This paper describes the operations of several types of gas monitors in use at the Idaho National Laboratory (INL) High Temperature Electrolysis Experiment (HTE) laboratory. The gases monitored at hydrogen, carbon monoxide, carbon dioxide, and oxygen. The operating time, calibration, and unwanted alarms are described. The calibration session time durations are described. Some simple statistics are given for the reliability of these monitors and the results are compared to operating experiences of other types of monitors.

The impact of age stereotypes on source monitoring in younger and older adults.

PubMed

Kuhlmann, Beatrice G; Bayen, Ute J; Meuser, Katharina; Kornadt, Anna E

2016-12-01

In 2 experiments, we examined reliance on age stereotypes when reconstructing the sources of statements. Two sources presented statements (half typical for a young adult, half for an old adult). Afterward, the sources' ages-23 and 70 years-were revealed and participants completed a source-monitoring task requiring attribution of statements to the sources. Multinomial model-based analyses revealed no age-typicality effect on source memory; however, age-typicality biased source-guessing: When not remembering the source, participants predominantly guessed the source for whose age the statement was typical. Thereby, people retrospectively described the sources as having made more statements that fit with stereotypes about their age group than they had truly made. In Experiment 1, older (60-84 years) participants' guessing bias was stronger than younger (17-26 years) participants', but they also had poorer source memory. Furthermore, older adults with better source memory were less biased than those with poorer source memory. Similarly, younger adults' age-stereotype reliance was larger when source memory was impaired in Experiment 2. Thus, age stereotypes bias source attributions, and individuals with poor source memory are particularly prone to this bias, which may contribute to the maintenance of age stereotypes over time. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Experiences of User Involvement in Mental Health Settings: User Motivations and Benefits.

PubMed

Neech, Sophie G B; Scott, Helen; Priest, Helena M; Bradley, Eleanor J; Tweed, Alison E

2018-05-12

Despite guidance promoting user involvement, meaningful involvement continues to be debated within services. To effectively implement involvement, it is important to acknowledge why users devote time to such activities. This study explores user representatives' experiences of involvement, including motivations and personal benefits. Thirteen user representatives involved in activities such as staff training and interviews were recruited from a UK National Health Service mental health Trust during 2015. Themes within semi-structured interviews were developed using constructivist grounded theory analysis. Memo-writing, process and focused coding, and core categories supported development of the conceptual framework of being a user representative. Being a user representative was inextricably linked to wellness, yet staff governed opportunities. Making a difference to others and giving back were initial motivating factors. Experiences depended on feeling valued, and the theme of transition captured shifts in identity. User representatives reported increased confidence and wellbeing when supported by staff. However, involvement triggered mental health difficulties, and identified need for regular monitoring and reflection of involvement activities and practice. Services should consider coproduction, where users and staff agree together on involvement definitions. Dedicated involvement workers are crucial to supporting individual wellbeing and monitoring involvement. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

A Lab Assembled Microcontroller-Based Sensor Module for Continuous Oxygen Measurement in Portable Hypoxia Chambers

PubMed Central

Mathupala, Saroj P.; Kiousis, Sam; Szerlip, Nicholas J.

2016-01-01

Background Hypoxia-based cell culture experiments are routine and essential components of in vitro cancer research. Most laboratories use low-cost portable modular chambers to achieve hypoxic conditions for cell cultures, where the sealed chambers are purged with a gas mixture of preset O2 concentration. Studies are conducted under the assumption that hypoxia remains unaltered throughout the 48 to 72 hour duration of such experiments. Since these chambers lack any sensor or detection system to monitor gas-phase O2, the cell-based data tend to be non-uniform due to the ad hoc nature of the experimental setup. Methodology With the availability of low-cost open-source microcontroller-based electronic project kits, it is now possible for researchers to program these with easy-to-use software, link them to sensors, and place them in basic scientific apparatus to monitor and record experimental parameters. We report here the design and construction of a small-footprint kit for continuous measurement and recording of O2 concentration in modular hypoxia chambers. The low-cost assembly (US$135) consists of an Arduino-based microcontroller, data-logging freeware, and a factory pre-calibrated miniature O2 sensor. A small, intuitive software program was written by the authors to control the data input and output. The basic nature of the kit will enable any student in biology with minimal experience in hobby-electronics to assemble the system and edit the program parameters to suit individual experimental conditions. Results/Conclusions We show the kit’s utility and stability of data output via a series of hypoxia experiments. The studies also demonstrated the critical need to monitor and adjust gas-phase O2 concentration during hypoxia-based experiments to prevent experimental errors or failure due to partial loss of hypoxia. Thus, incorporating the sensor-microcontroller module to a portable hypoxia chamber provides a researcher a capability that was previously available only to labs with access to sophisticated (and expensive) cell culture incubators. PMID:26862760

A Lab Assembled Microcontroller-Based Sensor Module for Continuous Oxygen Measurement in Portable Hypoxia Chambers.

PubMed

Mathupala, Saroj P; Kiousis, Sam; Szerlip, Nicholas J

2016-01-01

Hypoxia-based cell culture experiments are routine and essential components of in vitro cancer research. Most laboratories use low-cost portable modular chambers to achieve hypoxic conditions for cell cultures, where the sealed chambers are purged with a gas mixture of preset O2 concentration. Studies are conducted under the assumption that hypoxia remains unaltered throughout the 48 to 72 hour duration of such experiments. Since these chambers lack any sensor or detection system to monitor gas-phase O2, the cell-based data tend to be non-uniform due to the ad hoc nature of the experimental setup. With the availability of low-cost open-source microcontroller-based electronic project kits, it is now possible for researchers to program these with easy-to-use software, link them to sensors, and place them in basic scientific apparatus to monitor and record experimental parameters. We report here the design and construction of a small-footprint kit for continuous measurement and recording of O2 concentration in modular hypoxia chambers. The low-cost assembly (US$135) consists of an Arduino-based microcontroller, data-logging freeware, and a factory pre-calibrated miniature O2 sensor. A small, intuitive software program was written by the authors to control the data input and output. The basic nature of the kit will enable any student in biology with minimal experience in hobby-electronics to assemble the system and edit the program parameters to suit individual experimental conditions. We show the kit's utility and stability of data output via a series of hypoxia experiments. The studies also demonstrated the critical need to monitor and adjust gas-phase O2 concentration during hypoxia-based experiments to prevent experimental errors or failure due to partial loss of hypoxia. Thus, incorporating the sensor-microcontroller module to a portable hypoxia chamber provides a researcher a capability that was previously available only to labs with access to sophisticated (and expensive) cell culture incubators.

OCCUPATIONAL EXPOSURE TO RADON IN DIFFERENT KINDS OF NON-URANIUM MINES.

PubMed

Fan, D; Zhuo, W; Zhang, Y

2016-09-01

For more accurate assessments of the occupational exposure to radon for miners, the individual monitoring was conducted by using an improved passive integrating (222)Rn monitor. A total of 120 miners in 3 different kinds of mines were monitored throughout a year. The results showed that the individual exposure to radon significantly varied with types of mines and work. Compared with the exposure to coal miners, the exposure to copper miners was much higher. Furthermore, it was found that the exposure might be overestimated if the environmental (222)Rn monitored by the passive integrating monitors was used for assessment. The results indicate that the individual monitoring of radon is necessary for an accurate assessment of radon exposure to miners, and radon exposure to non-uranium miners should also be assessed from the viewpoint of radiation protection. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Individual differences in episodic memory abilities predict successful prospective memory output monitoring.

PubMed

Hunter Ball, B; Pitães, Margarida; Brewer, Gene A

2018-02-07

Output monitoring refers to memory for one's previously completed actions. In the context of prospective memory (PM) (e.g., remembering to take medication), failures of output monitoring can result in repetitions and omissions of planned actions (e.g., over- or under-medication). To be successful in output monitoring paradigms, participants must flexibly control attention to detect PM cues as well as engage controlled retrieval of previous actions whenever a particular cue is encountered. The current study examined individual differences in output monitoring abilities in a group of younger adults differing in attention control (AC) and episodic memory (EM) abilities. The results showed that AC ability uniquely predicted successful cue detection on the first presentation, whereas EM ability uniquely predicted successful output monitoring on the second presentation. The current study highlights the importance of examining external correlates of PM abilities and contributes to the growing body of research on individual differences in PM.

Von Hippel-Lindau Disease (VHL)

MedlinePlus

... tumors can be treated with focused high-dose irradiation. Individuals with VHL need careful monitoring by a ... tumors can be treated with focused high-dose irradiation. Individuals with VHL need careful monitoring by a ...

Operating experience review of an INL gas monitoring system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadwallader, Lee C.; DeWall, K. G.; Herring, J. S.

2015-03-12

This article describes the operations of several types of gas monitors in use at the Idaho National Laboratory (INL) High Temperature Electrolysis Experiment (HTE) laboratory. The gases monitored in the lab room are hydrogen, carbon monoxide, carbon dioxide, and oxygen. The operating time, calibration, and both actual and unwanted alarms are described. The calibration session time durations are described. In addition, some simple calculations are given to estimate the reliability of these monitors and the results are compared to operating experiences of other types of monitors.

Intact error monitoring in combat Veterans with post-traumatic stress disorder.

PubMed

Swick, Diane; Honzel, Nikki; Turken, U

2015-11-30

The error-related negativity (ERN) is a neuroelectric signature of performance monitoring during speeded response time tasks. Previous studies indicate that individuals with anxiety disorders show ERN enhancements that correlate with the degree of clinical symptomology. Less is known about the error monitoring system in post-traumatic stress disorder (PTSD). PTSD is characterized by impairments in the regulation of fear and other emotional responses, as well as deficits in maintaining cognitive control. Here, combat Veterans with PTSD were compared to control Veterans in two different versions of the flanker task (n=13 or 14 per group). Replicating and extending previous findings, PTSD patients showed an intact ERN in both experiments. In addition, task performance and error compensation behavior were intact. Finally, ERN amplitude showed no relationship with self-reported PTSD, depression, or post-concussive symptoms. These results suggest that error monitoring represents a relative strength in PTSD that can dissociate from cognitive control functions that are impaired, such as response inhibition and sustained attention. A healthy awareness of errors in external actions could be leveraged to improve interoceptive awareness of emotional state. The results could have positive implications for PTSD treatments that rely on self-monitoring abilities, such as neurofeedback and mindfulness training. Published by Elsevier Ireland Ltd.

Examining Korean and Korean American older adults' perceived acceptability of home-based monitoring technologies in the context of culture.

PubMed

Chung, Jane; Thompson, Hilaire J; Joe, Jonathan; Hall, Amanda; Demiris, George

2017-01-01

Despite the increasing use of home-based monitoring technologies by older adults, few studies have examined older adults' acceptance of these technologies, especially among people from diverse cultural groups. The purpose of this study was to explore Korean and Korean American older adults' attitudes toward and perceptions of home-based monitoring technologies in a cultural context. A qualitative analysis of focus groups and individual interviews using inductive coding methods and a constant comparative approach for emerging themes was conducted. Several cultural factors that determine the acceptability of home-based monitoring technologies were identified. Most notably, the necessity of living alone due to loosened filial tradition and immigration was a main motivator for adopting these technologies for both Korean and Korean Americans. The level of satisfaction with the health care system or therapeutic interaction affected participants' perceived need for technologies. Compared with the Korean American group, Korean older adults regarded the government's role as more important in increasing adoption and use of new technologies. Contextual factors need to be considered when explaining perceptions of home-based monitoring technologies among older adults from various ethnic groups and developing diffusion strategies according to end users' attitudes, experiences, and cultural backgrounds.

Rapid Analysis, Self-Calibrating Array for Air Monitoring

NASA Technical Reports Server (NTRS)

Homer, Margie L.; Shevade, Abhijit V.; Lara, Liana; Huerta, Ramon; Vergara, Alexander; Muezzinoglua, Mehmet K.

2012-01-01

Human space missions have critical needs for monitoring and control for life support systems. These systems have monitoring needs that include feedback for closed loop processes and quality control for environmental factors. Sensors and monitoring technologies assure that the air environment and water supply for the astronaut crew habitat fall within acceptable limits, and that the life support system is functioning properly and efficiently. The longer the flight duration and the more distant the destination, the more critical it becomes to have carefully monitored and automated control systems for life support. Past experiments with the JPL ENose have demonstrated a lifetime of the sensor array, with the software, of around 18 months. The lifetime of the calibration, for some analytes, was as long as 24 months. We are working on a sensor array and new algorithms that will include sensor response time in the analysis. The preliminary array analysis for two analytes shows that the analysis time, of an event, can be dropped from 45 minutes to less than10 minutes and array training time can be cut substantially. We will describe the lifetime testing of an array and show lifetime data on individual sensors. This progress will lead to more rapid identification of analytes, and faster training time of the array.

Skylab

NASA Image and Video Library

1970-01-01

This 1970 photograph shows the Skylab's Ultraviolet (UV) Spectrograph, an Apollo Telescope Mount instrument. Its telescope, with camera and TV capability, photographed the Sun in selected ultraviolet wavelengths. The spectrograph was used to record the spectrum of UV emissions, such as flares or filaments, from a small individual feature on the solar disc. Real-time TV was used by the crew to monitor the performance of the telescope, transmit to the ground, and record. The exposed films were retrieved by astronaut extravehicular activities. The Marshall Space Flight Center had program management responsibility for the development of the Skylab hardware and experiments.

Skylab

NASA Image and Video Library

1973-01-01

This 1973 chart details Skylab's Ultraviolet (UV) Spectrograph, an Apollo Telescope Mount instrument. Its telescope, with camera and TV capability, photographed the Sun in selected ultraviolet wavelengths. The spectrograph was used to record the spectrum of UV emissions, such as flares or filaments, from a small individual feature on the solar disc. Real-time TV was used by the crew to monitor performance of the telescope, transmit to the ground and record. The exposed films were retrieved by astronaut extravehicular activities. The Marshall Space Flight Center had program management responsibility for the development of the Skylab hardware and experiments.

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2016 OUTPATIENT GLUCOSE MONITORING CONSENSUS STATEMENT.

PubMed

Bailey, Timothy S; Grunberger, George; Bode, Bruce W; Handelsman, Yehuda; Hirsch, Irl B; Jovanovič, Lois; Roberts, Victor Lawrence; Rodbard, David; Tamborlane, William V; Walsh, John

2016-02-01

This document represents the official position of the American Association of Clinical Endocrinologists and American College of Endocrinology. Where there were no randomized controlled trials or specific U.S. FDA labeling for issues in clinical practice, the participating clinical experts utilized their judgment and experience. Every effort was made to achieve consensus among the committee members. Position statements are meant to provide guidance, but they are not to be considered prescriptive for any individual patient and cannot replace the judgment of a clinician.

Toward an operational water vapor remote sensing system using the global positioning system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gutman, S.I.; Chadwick, R.B.; Wolf, d.W.

1995-04-01

Water vapor is one of the most important constituents of the free atmosphere since it is the principal mechanism by which moisture and latent heat are transported and cause weather. Recent experiments have demonstrated that data from Global Positioning System (GPS) satellites can be used to monitor precipitable water vapor (PWV) with millimeter accuracy and sub-hourly temporal resolution. Major advantages of GPS-based systems include the following: they work under virtually all weather conditions; individual systems do not have to be calibrated; and, they are relatively inexpensive.

Psychotropic medication use among adolescents and young adults with an autism spectrum disorder: parent views about medication use and healthcare services.

PubMed

Lake, Johanna K; Vogan, Vanessa; Sawyer, Amanda; Weiss, Jonathan A; Lunsky, Yona

2015-04-01

Psychotropic medications are frequently used to treat mental health and behavioral issues in adolescents and adults with an autism spectrum disorder (ASD). Although parents of individuals with ASD frequently take on medication management for their child, there is limited literature on parent perspectives of their child's medication use or their views about the healthcare services they receive, particularly in adulthood. The current study examined and compared parents of adolescents and of young adults with ASD regarding their child's psychotropic medication use and their views about healthcare services. One hundred parents of adolescents and young adults with ASD (ages 12-30 years) completed an online survey about their experience with their child's healthcare services and medication use. Parents of young adults were less likely to use nonpharmacological services before using a psychotropic medication than were parents of adolescents. Parents of young adults were also less likely to believe that their prescribing healthcare provider had adequate expertise in ASD, and were less satisfied with how their prescriber monitored their child's medication use. Findings highlight the need to build capacity among healthcare providers supporting individuals with ASD as they transition into adulthood. There is also a need for improved medication monitoring and increased awareness of the different mental health challenges that individuals with ASD encounter as they age.

False Memories for Affective Information in Schizophrenia.

PubMed

Fairfield, Beth; Altamura, Mario; Padalino, Flavia A; Balzotti, Angela; Di Domenico, Alberto; Mammarella, Nicola

2016-01-01

Studies have shown a direct link between memory for emotionally salient experiences and false memories. In particular, emotionally arousing material of negative and positive valence enhanced reality monitoring compared to neutral material since emotional stimuli can be encoded with more contextual details and thereby facilitate the distinction between presented and imagined stimuli. Individuals with schizophrenia appear to be impaired in both reality monitoring and memory for emotional experiences. However, the relationship between the emotionality of the to-be-remembered material and false memory occurrence has not yet been studied. In this study, 24 patients and 24 healthy adults completed a false memory task with everyday episodes composed of 12 photographs that depicted positive, negative, or neutral outcomes. Results showed how patients with schizophrenia made a higher number of false memories than normal controls ( p  < 0.05) when remembering episodes with positive or negative outcomes. The effect of valence was apparent in the patient group. For example, it did not affect the production causal false memories ( p  > 0.05) resulting from erroneous inferences but did interact with plausible, script consistent errors in patients (i.e., neutral episodes yielded a higher degree of errors than positive and negative episodes). Affective information reduces the probability of generating causal errors in healthy adults but not in patients suggesting that emotional memory impairments may contribute to deficits in reality monitoring in schizophrenia when affective information is involved.

False Memories for Affective Information in Schizophrenia

PubMed Central

Fairfield, Beth; Altamura, Mario; Padalino, Flavia A.; Balzotti, Angela; Di Domenico, Alberto; Mammarella, Nicola

2016-01-01

Studies have shown a direct link between memory for emotionally salient experiences and false memories. In particular, emotionally arousing material of negative and positive valence enhanced reality monitoring compared to neutral material since emotional stimuli can be encoded with more contextual details and thereby facilitate the distinction between presented and imagined stimuli. Individuals with schizophrenia appear to be impaired in both reality monitoring and memory for emotional experiences. However, the relationship between the emotionality of the to-be-remembered material and false memory occurrence has not yet been studied. In this study, 24 patients and 24 healthy adults completed a false memory task with everyday episodes composed of 12 photographs that depicted positive, negative, or neutral outcomes. Results showed how patients with schizophrenia made a higher number of false memories than normal controls (p < 0.05) when remembering episodes with positive or negative outcomes. The effect of valence was apparent in the patient group. For example, it did not affect the production causal false memories (p > 0.05) resulting from erroneous inferences but did interact with plausible, script consistent errors in patients (i.e., neutral episodes yielded a higher degree of errors than positive and negative episodes). Affective information reduces the probability of generating causal errors in healthy adults but not in patients suggesting that emotional memory impairments may contribute to deficits in reality monitoring in schizophrenia when affective information is involved. PMID:27965600

ISHNE/EHRA expert consensus on remote monitoring of cardiovascular implantable electronic devices (CIEDs).

PubMed

Dubner, Sergio; Auricchio, Angelo; Steinberg, Jonathan S; Vardas, Panos; Stone, Peter; Brugada, Josep; Piotrowicz, Ryszard; Hayes, David L; Kirchhof, Paulus; Breithardt, Günter; Zareba, Wojciech; Schuger, Claudio; Aktas, Mehmet K; Chudzik, Michal; Mittal, Suneet; Varma, Niraj

2012-02-01

We are in the midst of a rapidly evolving era of technology-assisted medicine. The field of telemedicine provides the opportunity for highly individualized medical management in a way that has never been possible before. Evolving medical technologies using cardiac implantable devices (CIEDs) with capabilities for remote monitoring permit evaluation of multiple parameters of cardiovascular physiology and risk, including cardiac rhythm, device function, blood pressure values, the presence of myocardial ischaemia, and the degree of compensation of congestive heart failure. Cardiac risk, device status, and response to therapies can now be assessed with these electronic systems of detection and reporting. This document reflects the extensive experience from investigators and innovators around the world who are shaping the evolution of this rapidly expanding field, focusing in particular on implantable pacemakers (IPGs), implantable cardioverter-defibrillators (ICDs), devices for cardiac resynchronization therapy (CRT) (both, with and without defibrillation properties), loop recorders, and haemodynamic monitoring devices. This document covers the basic methodologies, guidelines for their use, experience with existing applications, and the legal and reimbursement aspects associated with their use. To adequately cover this important emerging topic, the International Society for Holter and Noninvasive Electrocardiology (ISHNE) and the European Heart Rhythm Association (EHRA) combined their expertise in this field. We hope that the development of this field can contribute to improve care of our cardiovascular patients.

A computerized assessment to compare the impact of standard, stereoscopic, and high-definition laparoscopic monitor displays on surgical technique.

PubMed

Feng, Chuan; Rozenblit, Jerzy W; Hamilton, Allan J

2010-11-01

Surgeons performing laparoscopic surgery have strong biases regarding the quality and nature of the laparoscopic video monitor display. In a comparative study, we used a unique computerized sensing and analysis system to evaluate the various types of monitors employed in laparoscopic surgery. We compared the impact of different types of monitor displays on an individual's performance of a laparoscopic training task which required the subject to move the instrument to a set of targets. Participants (varying from no laparoscopic experience to board-certified surgeons) were asked to perform the assigned task while using all three display systems, which were randomly assigned: a conventional laparoscopic monitor system (2D), a high-definition monitor system (HD), and a stereoscopic display (3D). The effects of monitor system on various performance parameters (total time consumed to finish the task, average speed, and movement economy) were analyzed by computer. Each of the subjects filled out a subjective questionnaire at the end of their training session. A total of 27 participants completed our study. Performance with the HD monitor was significantly slower than with either the 3D or 2D monitor (p < 0.0001). Movement economy with the HD monitor was significantly reduced compared with the 3D (p < 0.0004) or 2D (p < 0.0001) monitor. In terms of average time required to complete the task, performance with the 3D monitor was significantly faster than with the HD (p < 0.0001) or 2D (p < 0.0086) monitor. However, the HD system was the overwhelming favorite according to subjective evaluation. Computerized sensing and analysis is capable of quantitatively assessing the seemingly minor effect of monitor display on surgical training performance. The study demonstrates that, while users expressed a decided preference for HD systems, actual quantitative analysis indicates that HD monitors offer no statistically significant advantage and may even worsen performance compared with standard 2D or 3D laparoscopic monitors.

Monitoring-induced disruption in skilled typewriting.

PubMed

Snyder, Kristy M; Logan, Gordon D

2013-10-01

It is often disruptive to attend to the details of one's expert performance. The current work presents four experiments that utilized a monitor to report protocol to evaluate the sufficiency of three accounts of monitoring-induced disruption. The inhibition hypothesis states that disruption results from costs associated with preparing to withhold inappropriate responses. The dual-task hypothesis states that disruption results from maintaining monitored information in working memory. The implicit-explicit hypothesis states that disruption results from explicitly monitoring details of performance that are normally implicit. The findings suggest that all three hypotheses are sufficient to produce disruption, but inhibition and dual-task costs are not necessary. Experiment 1 showed that monitoring to report was disruptive even when there was no requirement to inhibit. Experiment 2 showed that maintaining information in working memory caused some disruption but much less than monitoring to report. Experiment 4 showed that monitoring to inhibit was more disruptive than monitoring to report, suggesting that monitoring is more disruptive when it is combined with other task requirements, such as inhibition. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Electrophysiological correlates of oxytocin-induced enhancement of social performance monitoring.

PubMed

de Bruijn, Ellen R A; Ruissen, Margit I; Radke, Sina

2017-10-01

Altered performance monitoring has been demonstrated after administration of different pharmacological compounds and in various clinical populations, such as excessive neurophysiological responses to mistakes in anxiety disorders. Here, a novel social pharmacological approach was applied to investigate whether oxytocin administration (24 IU) enhances performance monitoring for errors that have negative consequences for another individual, so-called social mistakes. Healthy male volunteers (N = 24) participated in a placebo-controlled crossover design. EEG measures were obtained while pairs of participants performed a speeded choice reaction-time task in an individual and social context. Following oxytocin administration, error-related negativity amplitudes were increased for social compared with individual mistakes. This increase was not found in the placebo condition. No effects of oxytocin were present in the individual context. The current study shows that oxytocin enhances performance monitoring specifically for social mistakes. This outcome is in line with a presumed role for oxytocin in salience attribution to social cues and underlines its context-dependency. Combining these processes may thus open up new research avenues and advance our understanding of individual differences in performance monitoring and oxytocin responses from a social neurocognitive, pharmacological and clinical perspective. © The Author (2017). Published by Oxford University Press.

User Centred Design and Nosocomials in Surgical ICUs: A Mobile Application for Peer Monitoring and Training in Hand Hygiene.

PubMed

Kariyawasam, Nadish; Wong, Ming Chao; Turner, Paul

2017-01-01

Nosocomial infections are a global public health risk. In low and middle-income countries the problem is acute with very high infection rates commonly contributing to poor patient outcomes including mortality. Organisational, cultural, and individual factors have been identified in these high rates, with poor hand hygiene compliance amongst clinicians a major risk factor. New approaches to achieving clinician behaviour change are required. User-centred approaches have proven effective to engage and support changes in clinician behaviours through the use of electronic tools. This paper reports on the experience of co-designing and implementing a mobile application with clinicians to enhance hand hygiene compliance. The peer monitoring and training supported by the application aims to directly contribute to evidence on reductions in infection rates in two surgical ICUs in Sri Lanka.

Temperature grid sensor for the measurement of spatial temperature distributions at object surfaces.

PubMed

Schäfer, Thomas; Schubert, Markus; Hampel, Uwe

2013-01-25

This paper presents results of the development and application of a new temperature grid sensor based on the wire-mesh sensor principle. The grid sensor consists of a matrix of 256 Pt1000 platinum chip resistors and an associated electronics that measures the grid resistances with a multiplexing scheme at high speed. The individual sensor elements can be spatially distributed on an object surface and measure transient temperature distributions in real time. The advantage compared with other temperature field measurement approaches such as infrared cameras is that the object under investigation can be thermally insulated and the radiation properties of the surface do not affect the measurement accuracy. The sensor principle is therefore suited for various industrial monitoring applications. Its applicability for surface temperature monitoring has been demonstrated through heating and mixing experiments in a vessel.

Distributed analysis functional testing using GangaRobot in the ATLAS experiment

NASA Astrophysics Data System (ADS)

Legger, Federica; ATLAS Collaboration

2011-12-01

Automated distributed analysis tests are necessary to ensure smooth operations of the ATLAS grid resources. The HammerCloud framework allows for easy definition, submission and monitoring of grid test applications. Both functional and stress test applications can be defined in HammerCloud. Stress tests are large-scale tests meant to verify the behaviour of sites under heavy load. Functional tests are light user applications running at each site with high frequency, to ensure that the site functionalities are available at all times. Success or failure rates of these tests jobs are individually monitored. Test definitions and results are stored in a database and made available to users and site administrators through a web interface. In this work we present the recent developments of the GangaRobot framework. GangaRobot monitors the outcome of functional tests, creates a blacklist of sites failing the tests, and exports the results to the ATLAS Site Status Board (SSB) and to the Service Availability Monitor (SAM), providing on the one hand a fast way to identify systematic or temporary site failures, and on the other hand allowing for an effective distribution of the work load on the available resources.

Constraining free riding in public goods games: designated solitary punishers can sustain human cooperation

PubMed Central

O'Gorman, Rick; Henrich, Joseph; Van Vugt, Mark

2008-01-01

Much of human cooperation remains an evolutionary riddle. Unlike other animals, people frequently cooperate with non-relatives in large groups. Evolutionary models of large-scale cooperation require not just incentives for cooperation, but also a credible disincentive for free riding. Various theoretical solutions have been proposed and experimentally explored, including reputation monitoring and diffuse punishment. Here, we empirically examine an alternative theoretical proposal: responsibility for punishment can be borne by one specific individual. This experiment shows that allowing a single individual to punish increases cooperation to the same level as allowing each group member to punish and results in greater group profits. These results suggest a potential key function of leadership in human groups and provides further evidence supporting that humans will readily and knowingly behave altruistically. PMID:18812292

Choosing the right analgesic. A guide to selection.

PubMed

Bushnell, Timothy G; Justins, Douglas M

1993-09-01

Pain is an unpleasant sensory and emotional experience, unique to each individual patient. In the dynamic processes of nociceptive stimulation, signal transmission, central decoding and interpretation there are many potential sites for pharmacological intervention, and there are many drugs which will produce analgesia. An analgesic 'ladder' has been proposed for rational pain relief in cancer and a similar concept should be used in all forms of acute and chronic pain. Continuing research and drug development undoubtedly extends our understanding, but consistent improvement in our clinical ability to relieve pain depends more on our willingness to consider the need of each patient individually, to tailor the drug, route and mode of administration to that patient's requirements, and then to monitor on the basis of the response of the patient to the treatment.

Multichamber Multipotentiostat System for Cellular Microphysiometry.

PubMed

Lima, Eduardo A; Snider, Rachel M; Reiserer, Ronald S; McKenzie, Jennifer R; Kimmel, Danielle W; Eklund, Sven E; Wikswo, John P; Cliffel, David E

2014-12-01

Multianalyte microphysiometry is a powerful technique for studying cellular metabolic flux in real time. Monitoring several analytes concurrently in a number of individual chambers, however, requires specific instrumentation that is not available commercially in a single, compact, benchtop form at an affordable cost. We developed a multipotentiostat system capable of performing simultaneous amperometric and potentiometric measurements in up to eight individual chambers. The modular design and custom LabVIEW™ control software provide flexibility and allow for expansion and modification to suit different experimental conditions. Superior accuracy is achieved when operating the instrument in a standalone configuration; however, measurements performed in conjunction with a previously developed multianalyte microphysiometer have shown low levels of crosstalk as well. Calibrations and experiments with primary and immortalized cell cultures demonstrate the performance of the instrument and its capabilities.

European isolation and confinement study. Additional experiments.

PubMed

Novara, M

1993-01-01

Microbiological Experiments. The ISEMSI microbiological contamination experiments confirmed known hypotheses, such as: the trend toward uniformity of skin microbial flora across a group of individuals enclosed together; the rather fast "colonization" of the environment by microorganisms shed by human inhabitants; and the heavy growth of microorganisms in poorly accessible and wet areas (toilets, air conditioning). In addition, possible disturbances of skin defense mechanisms against colonization by potentially pathogenic microbes were noted, as well as a difficulty in monitoring the microbial contents of the atmosphere (significant random variations occur between samples taken at different times and locations). Sensors for Atmospheric Contaminants. Several different prototypes of "array sensors" for the monitoring of trace gas contaminants in the atmosphere were evaluated during ISEMSI. Their performance was promising when compared with results achieved with a more conventional (and more complex) gas chromatograph/mass spectrometer device, also used during ISEMSI. An overall picture of the most important chemical contaminants to be found in enclosed, manned habitats (including contaminants produced by man himself) was obtained via the use of Tenax gas-adsorption traps. This permitted monitoring the fluctuation of contaminants on a daily basis, as well as during the complete 4-week period. Results will provide a valuable input for designing systems to monitor and control atmospheric contamination in future spacecraft. Particular attention was devoted to the monitoring of carbon monoxide in the chamber. Results showing the correlation between its concentration in the atmosphere and the percentage of carboxyhemoglobin in the EMSInauts' blood will allow the evaluation of the correctness of the presently specified maximum allowable concentration for spacecraft. Telemedicine Experiment. The telemedicine experiment confirmed the feasibility and importance of applying to a space station scenario many aspects of remote health care already widely used in the maritime environment. ISEMSI successfully evaluated telemedical consultation procedures and training protocols for the crew. EMSInauts, trained as paramedical assistants, had to interview a "patient" (another EMSInaut, trained to feign illness symptoms), prepare an anamnesis, carry out a medical examination, assess the severity of the case, and administer effective medical care under remote medical advice. An expert system was used to provide step-by-step guidance to the paramedical assistant. ISEMSI demonstrated the great importance of practicing and rehearsing emergency procedures; it confirmed that simulation of medical emergencies during an actual long-duration space mission will be required to provide "refresher training" to astronauts trained as paramedical assistants.(ABSTRACT TRUNCATED AT 400 WORDS)

Feeling the Insight: Uncovering Somatic Markers of the "aha" Experience.

PubMed

Shen, Wangbing; Tong, Yu; Yuan, Yuan; Zhan, Huijia; Liu, Chang; Luo, Jing; Cai, Houde

2018-03-01

Whether internal insight can be recognized by experiencing (somatic feeling) remains an unexplored problem. This study investigated the issue by examining potential somatic markers of the "aha" experience occurring at the moment of sudden insight. Participants were required to solve a set of compound remote associates (CRA) problems and were simultaneously monitored via electrodermal and cardiovascular recordings. The "aha"-related psychological components and somatic markers were determined by contrasting insightful solutions with non-insightful solutions. Results showed that the "aha" experience was an amalgam entailing positive affects and approached cognition accompanied by a greater mean skin conductance response (mSCR) amplitude and a marginally accelerated heart rate than the "no-aha" one. These results confirm and extend findings of the multidimensionality of the "aha" feeling and offer the first direct evidence of somatic markers, particularly an electrodermal signature of an "aha" feeling, which suggests a sudden insight could likely be experienced by individuals' external soma.

Hadfield during BP Reg Experiment Operations

NASA Image and Video Library

2013-04-17

ISS035-E-022360 (17 April 2013) --- In support of the Blood Pressure Regulation Experiment (BP Reg), Expedition 35 Commander Chris Hadfield of the Canadian Space Agency is pictured after having set up the Human Research Facility (HRF) PFS (Pulmonary Function System) and the European Physiology Module (EPM) Cardiolab (CDL) Leg/Arm Cuff System (LACS) and conducting the first ever session of this experiment. The test, which will be repeated using other crew members as well, will help to identify the astronauts who could benefit from countermeasures before returning to Earth. Thus, this method has great potential for astronaut health monitoring during future long-term space flights and it also has important implications for testing of individuals on Earth, especially the elderly, who are at risk for fainting. The research will also allow demonstrating the feasibility of obtaining a set of indicators of overall cardiovascular regulation from the non-invasive measurement of continuous blood pressure.

Hadfield during BP Reg Experiment Operations

NASA Image and Video Library

2013-04-17

ISS035-E-022357 (17 April 2013) --- In support of the Blood Pressure Regulation Experiment (BP Reg), Expedition 35 Commander Chris Hadfield of the Canadian Space Agency is pictured after having set up the Human Research Facility (HRF) PFS (Pulmonary Function System) and the European Physiology Module (EPM) Cardiolab (CDL) Leg/Arm Cuff System (LACS) and conducting the first ever session of this experiment. The test, which will be repeated using other crew members as well, will help to identify the astronauts who could benefit from countermeasures before returning to Earth. Thus, this method has great potential for astronaut health monitoring during future long-term space flights and it also has important implications for testing of individuals on Earth, especially the elderly, who are at risk for fainting. The research will also allow demonstrating the feasibility of obtaining a set of indicators of overall cardiovascular regulation from the non-invasive measurement of continuous blood pressure.

Hadfield during BP Reg Experiment Operations

NASA Image and Video Library

2013-04-17

ISS035-E-022356 (17 April 2013) --- In support of the Blood Pressure Regulation Experiment (BP Reg), Expedition 35 Commander Chris Hadfield of the Canadian Space Agency is pictured after having set up the Human Research Facility (HRF) PFS (Pulmonary Function System) and the European Physiology Module (EPM) Cardiolab (CDL) Leg/Arm Cuff System (LACS) and conducting the first ever session of this experiment. The test, which will be repeated using other crew members as well, will help to identify the astronauts who could benefit from countermeasures before returning to Earth. Thus, this method has great potential for astronaut health monitoring during future long-term space flights and it also has important implications for testing of individuals on Earth, especially the elderly, who are at risk for fainting. The research will also allow demonstrating the feasibility of obtaining a set of indicators of overall cardiovascular regulation from the non-invasive measurement of continuous blood pressure.

The Effect of Using Self-Monitoring Strategies in Social Studies Course on Self-Monitoring, Self-Regulation and Academic Achievement

ERIC Educational Resources Information Center

Arslantas, Suleyman; Kurnaz, Ahmet

2017-01-01

In an attempt to clarify the behavioral differences and a dimension of the individual's metacognitive processes, Snyder introduced the "Self-Monitoring Theory" in 1974. According to the theory, individuals differ in the extent to which they control their self-presentation in social interactions. Some people can observe and control their…

The assessment of biases in the acoustic discrimination of individuals

PubMed Central

Šálek, Martin

2017-01-01

Animal vocalizations contain information about individual identity that could potentially be used for the monitoring of individuals. However, the performance of individual discrimination is subjected to many biases depending on factors such as the amount of identity information, or methods used. These factors need to be taken into account when comparing results of different studies or selecting the most cost-effective solution for a particular species. In this study, we evaluate several biases associated with the discrimination of individuals. On a large sample of little owl male individuals, we assess how discrimination performance changes with methods of call description, an increasing number of individuals, and number of calls per male. Also, we test whether the discrimination performance within the whole population can be reliably estimated from a subsample of individuals in a pre-screening study. Assessment of discrimination performance at the level of the individual and at the level of call led to different conclusions. Hence, studies interested in individual discrimination should optimize methods at the level of individuals. The description of calls by their frequency modulation leads to the best discrimination performance. In agreement with our expectations, discrimination performance decreased with population size. Increasing the number of calls per individual linearly increased the discrimination of individuals (but not the discrimination of calls), likely because it allows distinction between individuals with very similar calls. The available pre-screening index does not allow precise estimation of the population size that could be reliably monitored. Overall, projects applying acoustic monitoring at the individual level in population need to consider limitations regarding the population size that can be reliably monitored and fine-tune their methods according to their needs and limitations. PMID:28486488

Experimental investigation of observation error in anuran call surveys

USGS Publications Warehouse

McClintock, B.T.; Bailey, L.L.; Pollock, K.H.; Simons, T.R.

2010-01-01

Occupancy models that account for imperfect detection are often used to monitor anuran and songbird species occurrence. However, presenceabsence data arising from auditory detections may be more prone to observation error (e.g., false-positive detections) than are sampling approaches utilizing physical captures or sightings of individuals. We conducted realistic, replicated field experiments using a remote broadcasting system to simulate simple anuran call surveys and to investigate potential factors affecting observation error in these studies. Distance, time, ambient noise, and observer abilities were the most important factors explaining false-negative detections. Distance and observer ability were the best overall predictors of false-positive errors, but ambient noise and competing species also affected error rates for some species. False-positive errors made up 5 of all positive detections, with individual observers exhibiting false-positive rates between 0.5 and 14. Previous research suggests false-positive errors of these magnitudes would induce substantial positive biases in standard estimators of species occurrence, and we recommend practices to mitigate for false positives when developing occupancy monitoring protocols that rely on auditory detections. These recommendations include additional observer training, limiting the number of target species, and establishing distance and ambient noise thresholds during surveys. ?? 2010 The Wildlife Society.

Skylab

NASA Image and Video Library

1973-01-01

This photograph is of Astronaut Kerwin wearing the Sleep Monitoring cap (Experiment M133) taken during the Skylab-2 mission. The Sleep Monitoring Experiment was a medical evaluation designed to objectively determine the amount and quality of crew members' inflight sleep. The experiment monitored and recorded electroencephalographic (EEG) and electrooculographic (EOG) activity during astronauts' sleep periods. One of the astronauts was selected for this experiment and wore a fitted cap during his sleep periods.

Fate of herbicides in a shallow aerobic aquifer: A continuous field injection experiment (Vejen, Denmark)

NASA Astrophysics Data System (ADS)

Broholm, Mette M.; Rügge, Kirsten; Tuxen, Nina; HøJberg, Anker L.; MosbæK, Hans; Bjerg, Poul L.

2001-12-01

A continuous, natural gradient, field injection experiment, involving six herbicides and a tracer, was performed in a shallow aerobic aquifer near Vejen, Denmark. Bentazone, (±)-2-(4-chloro-2-methylphenoxy) propanoic acid (MCPP), dichlorprop, isoproturon, and the dichlobenil metabolite 2,6-dichlor-benzamide (BAM) were injected along with 2-methyl-4,6-dinitrophenol (not discussed in this paper) and the tracer bromide. The injection lasted for 216 days and created a continuous plume in the aquifer. The plume was monitored in three dimensions in 96 multilevel samplers of 6-9 points each for 230 days, with selected individual points for a longer period. The bromide plume followed a complex path through the monitoring network downgradient of the injection wells. The plume movement was controlled by spatially varied hydraulic conductivities of the sand deposit and influenced by asynchronous seasonal variation in groundwater potentials. An average flow velocity of 0.5 m/d was observed, as depicted by bromide. Bentazone, BAM, MCPP, and dichlorprop retardation was negligible, and only slight retardation of isoproturon was observed in the continuous injection experiment and a preceding pulse experiment. No degradation of bentazone was observed in the aerobic aquifer during the monitoring period. BAM and isoproturon were not degraded within 5 m downgradient of the injection. The two phenoxy acids MCPP and dichlorprop were both degraded in the aerobic aquifer. Near the source a lag phase was observed followed by fast degradation of the phenoxy acids, indicating growth kinetics. The phenoxy acids were completely degraded within l m downgradient of the injection wells, resulting in the plumes being divided into small plumes at the injection wells and pulses farther downgradient. During the lag phase, phenoxy acids had spread beyond the 25 m long monitoring network. However, the mass of the phenoxy acids passing the 10-25 m fences never matched the corresponding bentazone or bromide masses, and the pulse was observed to shrink in size. This indicates that this pulse of phenoxy acids was being partially degraded at a low rate as it traveled through the aquifer.

Design of an Air Pollution Monitoring Campaign in Beijing for Application to Cohort Health Studies.

PubMed

Vedal, Sverre; Han, Bin; Xu, Jia; Szpiro, Adam; Bai, Zhipeng

2017-12-15

No cohort studies in China on the health effects of long-term air pollution exposure have employed exposure estimates at the fine spatial scales desirable for cohort studies with individual-level health outcome data. Here we assess an array of modern air pollution exposure estimation approaches for assigning within-city exposure estimates in Beijing for individual pollutants and pollutant sources to individual members of a cohort. Issues considered in selecting specific monitoring data or new monitoring campaigns include: needed spatial resolution, exposure measurement error and its impact on health effect estimates, spatial alignment and compatibility with the cohort, and feasibility and expense. Sources of existing data largely include administrative monitoring data, predictions from air dispersion or chemical transport models and remote sensing (specifically satellite) data. New air monitoring campaigns include additional fixed site monitoring, snapshot monitoring, passive badge or micro-sensor saturation monitoring and mobile monitoring, as well as combinations of these. Each of these has relative advantages and disadvantages. It is concluded that a campaign in Beijing that at least includes a mobile monitoring component, when coupled with currently available spatio-temporal modeling methods, should be strongly considered. Such a campaign is economical and capable of providing the desired fine-scale spatial resolution for pollutants and sources.

Design of an Air Pollution Monitoring Campaign in Beijing for Application to Cohort Health Studies

PubMed Central

Vedal, Sverre; Han, Bin; Szpiro, Adam; Bai, Zhipeng

2017-01-01

No cohort studies in China on the health effects of long-term air pollution exposure have employed exposure estimates at the fine spatial scales desirable for cohort studies with individual-level health outcome data. Here we assess an array of modern air pollution exposure estimation approaches for assigning within-city exposure estimates in Beijing for individual pollutants and pollutant sources to individual members of a cohort. Issues considered in selecting specific monitoring data or new monitoring campaigns include: needed spatial resolution, exposure measurement error and its impact on health effect estimates, spatial alignment and compatibility with the cohort, and feasibility and expense. Sources of existing data largely include administrative monitoring data, predictions from air dispersion or chemical transport models and remote sensing (specifically satellite) data. New air monitoring campaigns include additional fixed site monitoring, snapshot monitoring, passive badge or micro-sensor saturation monitoring and mobile monitoring, as well as combinations of these. Each of these has relative advantages and disadvantages. It is concluded that a campaign in Beijing that at least includes a mobile monitoring component, when coupled with currently available spatio-temporal modeling methods, should be strongly considered. Such a campaign is economical and capable of providing the desired fine-scale spatial resolution for pollutants and sources. PMID:29244738

Individuality and stability in male songs of cao vit gibbons (Nomascus nasutus) with potential to monitor population dynamics.

PubMed

Feng, Jun-Juan; Cui, Liang-Wei; Ma, Chang-Yong; Fei, Han-Lan; Fan, Peng-Fei

2014-01-01

Vocal individuality and stability has been used to conduct population surveys, monitor population dynamics, and detect dispersal patterns in avian studies. To our knowledge, it has never been used in these kinds of studies among primates. The cao vit gibbon is a critically endangered species with only one small population living in a karst forest along China-Vietnam border. Due to the difficult karst terrain, an international border, long life history, and similarity in male morphology, detailed monitoring of population dynamics and dispersal patterns are not possible using traditional observation methods. In this paper, we test individuality and stability in male songs of cao vit gibbons. We then discuss the possibility of using vocal individuality for population surveys and monitoring population dynamics and dispersal patterns. Significant individuality of vocalization was detected in all 9 males, and the correct rate of individual identification yielded by discriminant function analysis using a subset of variables was satisfactory (>90%). Vocal stability over 2-6 years was also documented in 4 males. Several characters of cao vit gibbons allowed long-term population monitoring using vocal recordings in both China and Vietnam: 1) regular loud calls, 2) strong individuality and stability in male songs, 3) stable territories, and 4) long male tenure. During the course of this research, we also observed one male replacement (confirmed by vocal analysis). This time- and labor-saving method might be the most effective way to detect dispersal patterns in this transboundary population.

Monitoring the hatch time of individual chicken embryos.

PubMed

Romanini, C E B; Exadaktylos, V; Tong, Q; McGonnel, I; Demmers, T G M; Bergoug, H; Eterradossi, N; Roulston, N; Garain, P; Bahr, C; Berckmans, D

2013-02-01

This study investigated variations in eggshell temperature (T(egg)) during the hatching process of broiler eggs. Temperature sensors monitored embryo temperature by registering T(egg) every minute. Measurements carried out on a sample of 40 focal eggs revealed temperature drops between 2 to 6°C during the last 3 d of incubation. Video cameras recorded the hatching process and served as the gold standard reference for manually labeling the hatch times of chicks. Comparison between T(egg) drops and the hatch time of individuals revealed a time synchronization with 99% correlation coefficient and an absolute average time difference up to 25 min. Our findings suggest that attaching temperature sensors to eggshells is a precise tool for monitoring the hatch time of individual chicks. Individual hatch monitoring registers the biological age of chicks and facilitates an accurate and reliable means to count hatching results and manage the hatch window.

10 CFR 60.143 - Monitoring and testing waste packages.

Code of Federal Regulations, 2010 CFR

2010-01-01

... package monitoring program shall include laboratory experiments which focus on the internal condition of... the laboratory experiments. (d) The waste package monitoring program shall continue as long as...

10 CFR 60.143 - Monitoring and testing waste packages.

Code of Federal Regulations, 2011 CFR

2011-01-01

... package monitoring program shall include laboratory experiments which focus on the internal condition of... the laboratory experiments. (d) The waste package monitoring program shall continue as long as...

10 CFR 60.143 - Monitoring and testing waste packages.

Code of Federal Regulations, 2012 CFR

2012-01-01

... package monitoring program shall include laboratory experiments which focus on the internal condition of... the laboratory experiments. (d) The waste package monitoring program shall continue as long as...

10 CFR 60.143 - Monitoring and testing waste packages.

Code of Federal Regulations, 2013 CFR

2013-01-01

... package monitoring program shall include laboratory experiments which focus on the internal condition of... the laboratory experiments. (d) The waste package monitoring program shall continue as long as...

10 CFR 60.143 - Monitoring and testing waste packages.

Code of Federal Regulations, 2014 CFR

2014-01-01

... package monitoring program shall include laboratory experiments which focus on the internal condition of... the laboratory experiments. (d) The waste package monitoring program shall continue as long as...

Compliance Groundwater Monitoring of Nonpoint Sources - Emerging Approaches

NASA Astrophysics Data System (ADS)

Harter, T.

2008-12-01

Groundwater monitoring networks are typically designed for regulatory compliance of discharges from industrial sites. There, the quality of first encountered (shallow-most) groundwater is of key importance. Network design criteria have been developed for purposes of determining whether an actual or potential, permitted or incidental waste discharge has had or will have a degrading effect on groundwater quality. The fundamental underlying paradigm is that such discharge (if it occurs) will form a distinct contamination plume. Networks that guide (post-contamination) mitigation efforts are designed to capture the shape and dynamics of existing, finite-scale plumes. In general, these networks extend over areas less than one to ten hectare. In recent years, regulatory programs such as the EU Nitrate Directive and the U.S. Clean Water Act have forced regulatory agencies to also control groundwater contamination from non-incidental, recharging, non-point sources, particularly agricultural sources (fertilizer, pesticides, animal waste application, biosolids application). Sources and contamination from these sources can stretch over several tens, hundreds, or even thousands of square kilometers with no distinct plumes. A key question in implementing monitoring programs at the local, regional, and national level is, whether groundwater monitoring can be effectively used as a landowner compliance tool, as is currently done at point-source sites. We compare the efficiency of such traditional site-specific compliance networks in nonpoint source regulation with various designs of regional nonpoint source monitoring networks that could be used for compliance monitoring. We discuss advantages and disadvantages of the site vs. regional monitoring approaches with respect to effectively protecting groundwater resources impacted by nonpoint sources: Site-networks provide a tool to enforce compliance by an individual landowner. But the nonpoint source character of the contamination and its typically large spatial extend requires extensive networks at an individual site to accurately and fairly monitor individual compliance. In contrast, regional networks seemingly fail to hold individual landowners accountable. But regional networks can effectively monitor large-scale impacts and water quality trends; and thus inform regulatory programs that enforce management practices tied to nonpoint source pollution. Regional monitoring networks for compliance purposes can face significant challenges in the implementation due to a regulatory and legal landscape that is exclusively structured to address point sources and individual liability, and due to the non-intensive nature of a regional monitoring program (lack of control of hot spots; lack of accountability of individual landowners).

Retrieval and validation of carbon dioxide, methane and water vapor for the Canary Islands IR-laser occultation experiment

NASA Astrophysics Data System (ADS)

Proschek, V.; Kirchengast, G.; Schweitzer, S.; Brooke, J. S. A.; Bernath, P. F.; Thomas, C. B.; Wang, J.-G.; Tereszchuk, K. A.; González Abad, G.; Hargreaves, R. J.; Beale, C. A.; Harrison, J. J.; Martin, P. A.; Kasyutich, V. L.; Gerbig, C.; Loescher, A.

2015-08-01

The first ground-based experiment to prove the concept of a novel space-based observation technique for microwave and infrared-laser occultation between low-Earth-orbit satellites was performed in the Canary Islands between La Palma and Tenerife. For two nights from 21 to 22 July 2011 the experiment delivered the infrared-laser differential transmission principle for the measurement of greenhouse gases (GHGs) in the free atmosphere. Such global and long-term stable measurements of GHGs, accompanied also by measurements of thermodynamic parameters and line-of-sight wind in a self-calibrating way, have become very important for climate change monitoring. The experiment delivered promising initial data for demonstrating the new observation concept by retrieving volume mixing ratios of GHGs along a ~144 km signal path at altitudes of ~2.4 km. Here, we present a detailed analysis of the measurements, following a recent publication that introduced the experiment's technical setup and first results for an example retrieval of CO2. We present the observational and validation data sets, the latter simultaneously measured at the transmitter and receiver sites; the measurement data handling; and the differential transmission retrieval procedure. We also determine the individual and combined uncertainties influencing the results and present the retrieval results for 12CO2, 13CO2, C18OO, H2O and CH4. The new method is found to have a reliable basis for monitoring of greenhouse gases such as CO2, CH4, and H2O in the free atmosphere.

Retrieval and validation of carbon dioxide, methane and water vapor for the Canary Islands IR-laser occultation experiment

NASA Astrophysics Data System (ADS)

Proschek, V.; Kirchengast, G.; Schweitzer, S.; Brooke, J. S. A.; Bernath, P. F.; Thomas, C. B.; Wang, J.-G.; Tereszchuk, K. A.; González Abad, G.; Hargreaves, R. J.; Beale, C. A.; Harrison, J. J.; Martin, P. A.; Kasyutich, V. L.; Gerbig, C.; Kolle, O.; Loescher, A.

2014-11-01

The first ground-based experiment to prove the concept of a novel space-based observation technique for microwave and infrared-laser occultation between Low Earth Orbit satellites (LMIO) was performed in the Canary Islands between La Palma and Tenerife in July 2011. This experiment aimed to demonstrate the infrared-laser differential transmission principle for the measurement of greenhouse gases (GHGs) in the free atmosphere. Such global and long-term stable measurements of GHGs, accompanied also by measurements of thermodynamic parameters and line-of-sight wind in a self-calibrating way, have become very important for climate change monitoring. The experiment delivered promising initial data for demonstrating the new observation concept by retrieving volume mixing ratios of GHGs along a ~ 144 km signal path at altitudes of ~ 2.4 km. Here, we present a detailed analysis of the measurements, following a recent publication that introduced the experiment's technical setup and first results for an example retrieval of CO2. We present the observational and validation datasets, the latter simultaneously measured at the transmitter and receiver sites, the measurement data handling, and the differential transmission retrieval procedure. We also determine the individual and combined uncertainties influencing the results and present the retrieval results for 12CO2, 13CO2, C18OO, H2O and CH4. The new method is found to have a reliable basis for monitoring of greenhouse gases such as CO2, CH4, and H2O in the free atmosphere.

Facial reactions to violent and comedy films: Association with callous-unemotional traits and impulsive aggression.

PubMed

Fanti, Kostas A; Kyranides, Melina Nicole; Panayiotou, Georgia

2017-02-01

The current study adds to prior research by investigating specific (happiness, sadness, surprise, disgust, anger and fear) and general (corrugator and zygomatic muscle activity) facial reactions to violent and comedy films among individuals with varying levels of callous-unemotional (CU) traits and impulsive aggression (IA). Participants at differential risk of CU traits and IA were selected from a sample of 1225 young adults. In Experiment 1, participants (N = 82) facial expressions were recorded while they watched violent and comedy films. Video footage of participants' facial expressions was analysed using FaceReader, a facial coding software that classifies facial reactions. Findings suggested that individuals with elevated CU traits showed reduced facial reactions of sadness and disgust to violent films, indicating low empathic concern in response to victims' distress. In contrast, impulsive aggressors produced specifically more angry facial expressions when viewing violent and comedy films. In Experiment 2 (N = 86), facial reactions were measured by monitoring facial electromyography activity. FaceReader findings were verified by the reduced facial electromyography at the corrugator, but not the zygomatic, muscle in response to violent films shown by individuals high in CU traits. Additional analysis suggested that sympathy to victims explained the association between CU traits and reduced facial reactions to violent films.

The modulating effect of personality traits on neural error monitoring: evidence from event-related FMRI.

PubMed

Sosic-Vasic, Zrinka; Ulrich, Martin; Ruchsow, Martin; Vasic, Nenad; Grön, Georg

2012-01-01

The present study investigated the association between traits of the Five Factor Model of Personality (Neuroticism, Extraversion, Openness for Experiences, Agreeableness, and Conscientiousness) and neural correlates of error monitoring obtained from a combined Eriksen-Flanker-Go/NoGo task during event-related functional magnetic resonance imaging in 27 healthy subjects. Individual expressions of personality traits were measured using the NEO-PI-R questionnaire. Conscientiousness correlated positively with error signaling in the left inferior frontal gyrus and adjacent anterior insula (IFG/aI). A second strong positive correlation was observed in the anterior cingulate gyrus (ACC). Neuroticism was negatively correlated with error signaling in the inferior frontal cortex possibly reflecting the negative inter-correlation between both scales observed on the behavioral level. Under present statistical thresholds no significant results were obtained for remaining scales. Aligning the personality trait of Conscientiousness with task accomplishment striving behavior the correlation in the left IFG/aI possibly reflects an inter-individually different involvement whenever task-set related memory representations are violated by the occurrence of errors. The strong correlations in the ACC may indicate that more conscientious subjects were stronger affected by these violations of a given task-set expressed by individually different, negatively valenced signals conveyed by the ACC upon occurrence of an error. Present results illustrate that for predicting individual responses to errors underlying personality traits should be taken into account and also lend external validity to the personality trait approach suggesting that personality constructs do reflect more than mere descriptive taxonomies.

Low-cost and disposable pressure sensor mat for non-invasive sleep and movement monitoring applications.

PubMed

Abraham, Jose K; Sullivan, Shawn; Ranganathan, Sridhar

2011-01-01

Sleep has profound effects on the physical and mental well-being of an individual. The National Institutes of Health (NIH) Sleep Disorder Research Plan gives particular emphasis to non-invasive sleep monitoring methods. Older adults experience sleep fragmentation due to sleep disorders. Unobtrusive non-contact monitoring can be the only realistic solution for long term home-based sleep monitoring. The demand for a low-cost and non-invasive sleep monitoring system for in-home use is more than before due to an increasingly stressful life style. Cost and complexity of current sensor elements hinder the development of low-cost sleep monitoring devices for in-home use. This paper presents the design, development and implementation of a low-cost and disposable pressure sensor mat that could be useful for in-home sleep and movement monitoring applications. The sensor mat design is based on a compressible foam sandwiched between two orthogonal arrays of cPaper capacitance sensors. A low-cost conducting paper has been developed for use as the capacitance sensor electrode. Typical mat design uses a 3 mm thick foam with 5 mm row/column grid array shows that it has a measurement resolution of 0.1 PSI pressure. The resolution can be controlled by both modifying properties of the conducting paper and the foam. Since this pressure mat design is based on low-cost paper, the sensor electrodes are disposable or semi-durable and hence it is ideal for the use in point-of-care physiological monitoring, pervasive healthcare and consumer electronic devices.

Experiences with radiation portal detectors for international rail transport

NASA Astrophysics Data System (ADS)

Stromswold, D. C.; McCormick, K.; Todd, L.; Ashbaker, E. D.; Evans, J. C.

2006-08-01

Radiation detectors monitored trains at two international borders to evaluate the performance of NaI(Tl) and plastic (polyvinyltoluene: PVT) gamma-ray detectors to characterize rail cargo. The detectors included a prototype NaI(Tl) radiation-portal-monitor panel having four large detectors (10-cm × 10-cm × 41-cm) and a PVT panel with a 41 cm × 173 cm × 3.8-cm detector. Spectral data from the NaI(Tl) and PVT detectors were recorded. Of particular emphasis was the identification of naturally occurring radioactive material (NORM) and the resultant frequency of nuisance alarms. For rail monitoring, the difficulty in stopping trains to perform secondary inspection on alarming cars creates a need for reliable identification of NORM during initial screening. Approximately 30 trains were monitored, and the commodities in individual railcars were ascertained from manifest information. At one test site, the trains carried inter-modal containers that had been unloaded from ships, and at the other site, the trains contained bulk cargo in tanker cars and hopper cars or individual items in boxcars or flatbeds. NORM encountered included potash, liquefied petroleum gas, fireworks, televisions, and clay-based products (e.g., pottery). Analysis of the spectral data included the use of the template-fitting portion of the program GADRAS developed at Sandia National Laboratories. For most of the NORM, the NaI(Tl) data produced a correct identification of the radionuclides present in the railcars. The same analysis was also used for PVT data in which the spectral information (no peaks but only gradual spectral changes including Compton edges) was limited. However, the PVT analysis provided correct identification of 40K and 226Ra in many cases.

Use of a Computerized Tracking System to Monitor and Provide Feedback on Dietary Goals for Calorie-Restricted Diets: The POUNDS LOST Study

PubMed Central

Anton, Stephen D.; LeBlanc, Eric; Allen, H. Raymond; Karabetian, Christy; Sacks, Frank; Bray, George; Williamson, Donald A.

2012-01-01

The use of self-monitoring as a tool to facilitate behavioral modification is common in many lifestyle-based weight loss interventions. Electronic tracking programs, including computer-based systems and smart phone applications, have been developed to allow individuals to self-monitor their behavior digitally. These programs offer an advantage over traditional self-report modalities in that they can provide users with direct feedback about dietary and/or physical activity adherence levels and thereby assist them in real-time decision making. This article describes the use of an Internet-based computerized tracking system (CTS) that was developed specifically for the POUNDS LOST study, a 2-year randomized controlled trial designed to test the efficacy of four macronutrient diets for weight and fat reduction in healthy, overweight men and women (body mass index range = 25.0–39.9 kg/m2). The CTS served many functions in this study, including data collection, dietary and exercise assessment and feedback, messaging system, and report generation. Across all groups, participants with high usage of the CTS during the initial 8 weeks lost greater amounts of weight than participants with low usage (8.7% versus 5.5% of initial body weight, respectively; p < .001) at week 32. Rates of CTS utilization were highest during the first year of this 2-year intervention, and utilization of the CTS declined steadily over time. The unique features of the CTS combined with technological developments, such as smart phone applications, offer significant potential to improve the user’s self-monitoring experience and adherence to health promotion programs designed specifically for individuals with obesity and type 2 diabetes. PMID:23063049

Experiences with radiation portal detectors for international rail transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stromswold, David C.; McCormick, Kathleen R.; Todd, Lindsay C.

Radiation detectors monitored trains at two international borders to evaluate the performance of NaI(Tl) and plastic (polyvinyltoluene: PVT) gamma-ray detectors to characterize rail cargo. The detectors included a prototype NaI(Tl) radiation-portal-monitor panel having four large detectors (10-cm × 10-cm × 41-cm) and a PVT panel with a 41 cm × 173 cm × 3.8-cm detector. Spectral data from the NaI(Tl) and PVT detectors were recorded. Of particular emphasis was the identification of naturally occurring radioactive material (NORM) and the resultant frequency of nuisance alarms. For rail monitoring, the difficulty in stopping trains to perform secondary inspection on alarming cars createsmore » a need for reliable identification of NORM during initial screening. Approximately 30 trains were monitored, and the commodities in individual railcars were ascertained from manifest information. At one test site the trains carried inter-modal containers that had been unloaded from ships, and at the other site the trains contained bulk cargo or individual items in boxcars or flatbeds. NORM encountered included potash, liquefied petroleum gas, fireworks, televisions, and clay-based products (e.g., pottery). Analysis of the spectral data included the use of the template-fitting program GADRAS/FitToDB from Sandia National Laboratories. For much of the NORM the NaI(Tl) data produced a correct identification of the radionuclides present in the railcars. The same analysis was also used for PVT data in which the spectral information (no peaks but only gradual spectral changes including Compton edges) was limited. However, the PVT analysis provided correct identification of 40K and 226Ra in many cases.« less

Performance evaluation of a health insurance in Nigeria using optimal resource use: health care providers perspectives

PubMed Central

2014-01-01

Background Performance measures are often neglected during the transition period of national health insurance scheme implementation in many low and middle income countries. These measurements evaluate the extent to which various aspects of the schemes meet their key objectives. This study assesses the implementation of a health insurance scheme using optimal resource use domains and examines possible factors that influence each domain, according to providers’ perspectives. Methods A retrospective, cross-sectional survey was done between August and December 2010 in Kaduna state, and 466 health care provider personnel were interviewed. Optimal-resource-use was defined in four domains: provider payment mechanism (capitation and fee-for-service payment methods), benefit package, administrative efficiency, and active monitoring mechanism. Logistic regression analysis was used to identify provider factors that may influence each domain. Results In the provider payment mechanism domain, capitation payment method (95%) performed better than fee-for-service payment method (62%). Benefit package domain performed strongly (97%), while active monitoring mechanism performed weakly (37%). In the administrative efficiency domain, both promptness of referral system (80%) and prompt arrival of funds (93%) performed well. At the individual level, providers with fewer enrolees encountered difficulties with reimbursement. Other factors significantly influenced each of the optimal-resource-use domains. Conclusions Fee-for-service payment method and claims review, in the provider payment and active monitoring mechanisms, respectively, performed weakly according to the providers’ (at individual-level) perspectives. A short-fall on the supply-side of health insurance could lead to a direct or indirect adverse effect on the demand-side of the scheme. Capitation payment per enrolees should be revised to conform to economic circumstances. Performance indicators and providers’ characteristics and experiences associated with resource use can assist policy makers to monitor and evaluate health insurance implementation. PMID:24628889

Planetary and Space Simulation Facilities PSI at DLR for Astrobiology

NASA Astrophysics Data System (ADS)

Rabbow, E.; Rettberg, P.; Panitz, C.; Reitz, G.

2008-09-01

Ground based experiments, conducted in the controlled planetary and space environment simulation facilities PSI at DLR, are used to investigate astrobiological questions and to complement the corresponding experiments in LEO, for example on free flying satellites or on space exposure platforms on the ISS. In-orbit exposure facilities can only accommodate a limited number of experiments for exposure to space parameters like high vacuum, intense radiation of galactic and solar origin and microgravity, sometimes also technically adapted to simulate extraterrestrial planetary conditions like those on Mars. Ground based experiments in carefully equipped and monitored simulation facilities allow the investigation of the effects of simulated single environmental parameters and selected combinations on a much wider variety of samples. In PSI at DLR, international science consortia performed astrobiological investigations and space experiment preparations, exposing organic compounds and a wide range of microorganisms, reaching from bacterial spores to complex microbial communities, lichens and even animals like tardigrades to simulated planetary or space environment parameters in pursuit of exobiological questions on the resistance to extreme environments and the origin and distribution of life. The Planetary and Space Simulation Facilities PSI of the Institute of Aerospace Medicine at DLR in Köln, Germany, providing high vacuum of controlled residual composition, ionizing radiation of a X-ray tube, polychromatic UV radiation in the range of 170-400 nm, VIS and IR or individual monochromatic UV wavelengths, and temperature regulation from -20°C to +80°C at the sample size individually or in selected combinations in 9 modular facilities of varying sizes are presented with selected experiments performed within.

The colony environment modulates sleep in honey bee workers.

PubMed

Eban-Rothschild, Ada; Bloch, Guy

2015-02-01

One of the most important and evolutionarily conserved roles of sleep is the processing and consolidation of information acquired during wakefulness. In both insects and mammals, environmental and social stimuli can modify sleep physiology and behavior, yet relatively little is known about the specifics of the wake experiences and their relative contribution to experience-dependent modulation of sleep. Honey bees provide an excellent model system in this regard because their behavioral repertoire is well characterized and the environment they experience during the day can be manipulated while keeping an ecologically and sociobiologically relevant context. We examined whether social experience modulates sleep in honey bees, and evaluated the relative contribution of different social signals. We exposed newly emerged bees to different components of their natural social environment and then monitored their sleep behavior in individual cages in a constant lab environment. We found that rich waking experience modulates subsequent sleep. Bees that experienced the colony environment for 1 or 2 days slept more than same-age sister bees that were caged individually or in small groups in the lab. Furthermore, bees placed in mesh-enclosures in the colony, that prevented direct contact with nestmates, slept similarly to bees freely moving in the colony. These results suggest that social signals that do not require direct or close distance interactions between bees are sufficiently rich to encompass almost the entire effect of the colony on sleep. Our findings provide a remarkable example of social experience-dependent modulation of an essential biological process. © 2015. Published by The Company of Biologists Ltd.

The Hard Problem of Cooperation

PubMed Central

Eriksson, Kimmo; Strimling, Pontus

2012-01-01

Based on individual variation in cooperative inclinations, we define the “hard problem of cooperation” as that of achieving high levels of cooperation in a group of non-cooperative types. Can the hard problem be solved by institutions with monitoring and sanctions? In a laboratory experiment we find that the answer is affirmative if the institution is imposed on the group but negative if development of the institution is left to the group to vote on. In the experiment, participants were divided into groups of either cooperative types or non-cooperative types depending on their behavior in a public goods game. In these homogeneous groups they repeatedly played a public goods game regulated by an institution that incorporated several of the key properties identified by Ostrom: operational rules, monitoring, rewards, punishments, and (in one condition) change of rules. When change of rules was not possible and punishments were set to be high, groups of both types generally abided by operational rules demanding high contributions to the common good, and thereby achieved high levels of payoffs. Under less severe rules, both types of groups did worse but non-cooperative types did worst. Thus, non-cooperative groups profited the most from being governed by an institution demanding high contributions and employing high punishments. Nevertheless, in a condition where change of rules through voting was made possible, development of the institution in this direction was more often voted down in groups of non-cooperative types. We discuss the relevance of the hard problem and fit our results into a bigger picture of institutional and individual determinants of cooperative behavior. PMID:22792282

40 CFR 141.563 - What follow-up action is my system required to take based on continuous turbidity monitoring?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Individual Filter Turbidity Requirements § 141.563 What follow-up action is my system required to take based...: If * * * Your system must * * * (a) The turbidity of an individual filter (or the turbidity of combined filter effluent (CFE) for systems with 2 filters that monitor CFE in lieu of individual filters...

40 CFR 141.563 - What follow-up action is my system required to take based on continuous turbidity monitoring?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Individual Filter Turbidity Requirements § 141.563 What follow-up action is my system required to take based...: If * * * Your system must * * * (a) The turbidity of an individual filter (or the turbidity of combined filter effluent (CFE) for systems with 2 filters that monitor CFE in lieu of individual filters...

40 CFR 141.563 - What follow-up action is my system required to take based on continuous turbidity monitoring?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Individual Filter Turbidity Requirements § 141.563 What follow-up action is my system required to take based...: If * * * Your system must * * * (a) The turbidity of an individual filter (or the turbidity of combined filter effluent (CFE) for systems with 2 filters that monitor CFE in lieu of individual filters...

40 CFR 141.563 - What follow-up action is my system required to take based on continuous turbidity monitoring?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Individual Filter Turbidity Requirements § 141.563 What follow-up action is my system required to take based...: If * * * Your system must * * * (a) The turbidity of an individual filter (or the turbidity of combined filter effluent (CFE) for systems with 2 filters that monitor CFE in lieu of individual filters...

40 CFR 141.563 - What follow-up action is my system required to take based on continuous turbidity monitoring?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Individual Filter Turbidity Requirements § 141.563 What follow-up action is my system required to take based...: If * * * Your system must * * * (a) The turbidity of an individual filter (or the turbidity of combined filter effluent (CFE) for systems with 2 filters that monitor CFE in lieu of individual filters...

Self-Monitoring Using Continuous Glucose Monitors with Real-Time Feedback Improves Exercise Adherence in Individuals with Impaired Blood Glucose: A Pilot Study.

PubMed

Bailey, Kaitlyn J; Little, Jonathan P; Jung, Mary E

2016-03-01

Exercise helps individuals with prediabetes or type 2 diabetes (T2D) manage their blood glucose (BG); however, exercise adherence in this population is dismal. In this pilot study we tested the efficacy of a self-monitoring group-based intervention using continuous glucose monitors (CGMs) at increasing exercise adherence in individuals with impaired BG. Thirteen participants with prediabetes or T2D were randomized to an 8-week standard care exercise program (CON condition) (n = 7) or self-monitoring exercise intervention (SM condition) (n = 6). Participants in the SM condition were taught how to self-monitor their exercise and BG, to goal set, and to use CGM to observe how exercise influences BG. We hypothesized that compared with the CON condition, using a real-time CGM would facilitate self-monitoring behavior, resulting in increased exercise adherence. Repeated-measures analysis of variance revealed significant Condition × Time interactions for self-monitoring (P < 0.01), goal setting (P = 0.01), and self-efficacy to self-monitor (P = 0.01), such that the SM condition showed greater increases in these outcomes immediately after the program and at the 1-month follow-up compared with the CON condition. The SM condition had higher program attendance rates (P = 0.03), and a greater proportion of participants reregistered for additional exercise programs (P = 0.048) compared with the CON condition. Participants in both conditions experienced improvements in health-related quality of life, waist circumference, and fitness (P values <0.05). These findings provide promising initial support for the use of a real-time CGM to foster self-monitoring and exercise behavior in individuals living with prediabetes or T2D.

A rapid review of the impact of commissioning on service use, quality, outcomes and value for money: implications for Australian policy.

PubMed

Gardner, Karen; Davies, G Powell; Edwards, Karen; McDonald, Julie; Findlay, Terry; Kearns, Rachael; Joshi, Chandni; Harris, Mark

2016-01-01

The aim of this systematic review was to assess evidence of the impact of commissioning on health service use, quality, outcomes and value for money and to consider findings in the Australian context. Systematic searches of the literature identified 444 papers and, after exclusions, 36 were subject to full review. The commissioning cycle (planning, contracting, monitoring) formed a framework for analysis and impacts were assessed at individual, subpopulation and population levels. Little evidence of the effectiveness of commissioning at any level was available and observed impacts were highly context-dependent. There was insufficient evidence to identify a preferred model. Lack of skills and capacity were cited as major barriers to the implementation of commissioning. Successful commissioning requires a clear policy framework of national and regional priorities that define agreed targets for commissioning agencies. Engagement of consumers and providers, especially physicians, was considered to be critically important but is time consuming and has proven difficult to sustain. Adequate information on the cost, volume and quality of healthcare services is critically important for setting priorities, and for contracting and monitoring performance. Lack of information resulted in serious problems. High-quality nationally standardised performance measures and data requirements need to be built into contracts and ongoing monitoring and evaluation. In Australia, there is significant work to be done in areas of policy and governance, funding systems and incentives, patient enrolment or registration, information systems, individual and organisational capacity, community engagement and experience in commissioning.

A visual analytics approach for pattern-recognition in patient-generated data.

PubMed

Feller, Daniel J; Burgermaster, Marissa; Levine, Matthew E; Smaldone, Arlene; Davidson, Patricia G; Albers, David J; Mamykina, Lena

2018-06-13

To develop and test a visual analytics tool to help clinicians identify systematic and clinically meaningful patterns in patient-generated data (PGD) while decreasing perceived information overload. Participatory design was used to develop Glucolyzer, an interactive tool featuring hierarchical clustering and a heatmap visualization to help registered dietitians (RDs) identify associative patterns between blood glucose levels and per-meal macronutrient composition for individuals with type 2 diabetes (T2DM). Ten RDs participated in a within-subjects experiment to compare Glucolyzer to a static logbook format. For each representation, participants had 25 minutes to examine 1 month of diabetes self-monitoring data captured by an individual with T2DM and identify clinically meaningful patterns. We compared the quality and accuracy of the observations generated using each representation. Participants generated 50% more observations when using Glucolyzer (98) than when using the logbook format (64) without any loss in accuracy (69% accuracy vs 62%, respectively, p = .17). Participants identified more observations that included ingredients other than carbohydrates using Glucolyzer (36% vs 16%, p = .027). Fewer RDs reported feelings of information overload using Glucolyzer compared to the logbook format. Study participants displayed variable acceptance of hierarchical clustering. Visual analytics have the potential to mitigate provider concerns about the volume of self-monitoring data. Glucolyzer helped dietitians identify meaningful patterns in self-monitoring data without incurring perceived information overload. Future studies should assess whether similar tools can support clinicians in personalizing behavioral interventions that improve patient outcomes.

Perspectives on Self-Management in Multiple Sclerosis

PubMed Central

Knaster, Elizabeth S.; Johnson, Kurt; McMullen, Kara A.; Ehde, Dawn M.

2011-01-01

The aim of this study was to elucidate the experience of self-management among people with multiple sclerosis (MS) and gather their input to inform a self-management intervention. Twelve people with MS participated in focus groups in which they were asked open-ended questions about MS symptoms, challenges, overcoming challenges, symptom management, and treatment preferences. The results suggest four major themes: 1) “The Everyday Experience of MS,” including comments about symptoms and their impact on functioning; 2) “Motivation for Self-Management,” including descriptions of motivation originating from physical necessity, success with other management techniques, and external sources; 3) “Coping Strategies and Skills,” including descriptions of changing behaviors, expanding social support networks, finding resources, utilizing medical treatment, and monitoring symptoms; and 4) “Vision for a Self-Management Intervention,” including suggestions that an intervention be individualized, be motivating, and provide resources. The results of this study can inform the design and implementation of self-management interventions. Experiences described by participants are consistent with other qualitative reports suggesting the active role people with MS play in managing their condition. Intervention approaches must consider the complex constellation of symptoms associated with MS and provide individualized treatments that enhance the person's ability to manage their symptoms, barriers presented by such symptoms, and their health care. PMID:24453718

Severe mutilation of a Critically Endangered Taiwanese humpback dolphin Sousa chinensis taiwanensis by fishing gear.

PubMed

Wang, John Y; Araújo-Wang, Claryana

2017-03-21

Direct observations of the causes of injuries to cetaceans are rare events. For very small and declining populations, such events may be even less likely to be observed because of the few individuals that remain. A long-term monitoring program using photographic identification of individuals resulted in the documentation of an individual Taiwanese humpback dolphin Sousa chinensis taiwanensis that survived a harmful interaction with fishing gear. An adult female that was accompanied by a young calf sustained massive damage to several tissue types on her dorsal surface. From the injuries, it is clear that the animal had suffered intense trauma that likely caused pain for several months as the fishing gear sliced through its dorsal hump and fin. Given the incredible mutilation, the animal is likely compromised at some level and probably continues to experience ongoing pain. This case, along with observations of other individuals in this population bearing serious injuries or being entangled in fishing gear, is direct evidence that the impacts of local fisheries on this subspecies are almost certainly unsustainable.

Understanding the basis of shortnose sturgeon (Acipenser brevirostrum) partial migration in the Gulf of Maine

USGS Publications Warehouse

Altenritter, Matthew E.; Zydlewski, Gayle B.; Kinnison, Michael T.; Zydlewski, Joseph D.; Wippelhauser, Gail S.

2018-01-01

Movement of shortnose sturgeon (Acipenser brevirostrum) among major river systems in the Gulf of Maine is common and has implications for the management of this endangered species. Directed movements of 61 telemetered individuals monitored between 2010 and 2013 were associated with the river of tagging and individual characteristics. While a small proportion of fish tagged in the Kennebec River moved to the Penobscot River (5%), a much higher proportion of fish tagged in the Penobscot River moved to the Kennebec River (66%), during probable spawning windows. This suggests that Penobscot River fish derive from a migratory contingent within a larger Kennebec River population. Despite this connectivity, fish captured in the Penobscot River were larger (∼100 mm fork length) and had higher condition factors (median Fulton’s K: 0.76) than those captured in the Kennebec River (median Fulton’s K: 0.61). Increased abundance and resource limitation in the Kennebec River may be constraining growth and promoting migration to the Penobscot River by individuals with sufficient initial size and condition. Migrants could experience an adaptive reproductive advantage relative to nonmigratory individuals.

Using cross-correlations of random wavefields for surface waves tomography and structural health monitoring.

NASA Astrophysics Data System (ADS)

Sabra, K.

2006-12-01

The random nature of noise and scattered fields tends to suggest limited utility. Indeed, seismic or acoustic fields from random sources or scatterers are often considered to be incoherent, but there is some coherence between two sensors that receive signals from the same individual source or scatterer. An estimate of the Green's function (or impulse response) between two points can be obtained from the cross-correlation of random wavefields recorded at these two points. Recent theoretical and experimental studies in ultrasonics, underwater acoustics, structural monitoring and seismology have investigated this technique in various environments and frequency ranges. These results provide a means for passive imaging using only the random wavefields, without the use of active sources. The coherent wavefronts emerge from a correlation process that accumulates contributions over time from random sources whose propagation paths pass through both receivers. Results will be presented from experiments using ambient noise cross-correlations for the following applications: 1) passive surface waves tomography from ocean microseisms and 2) structural health monitoring of marine and airborne structures embedded in turbulent flow.

Flight physiology training experiences and perspectives: survey of 117 pilots.

PubMed

Patrão, Luís; Zorro, Sara; Silva, Jorge; Castelo-Branco, Miguel; Ribeiro, João

2013-06-01

Human factors and awareness of flight physiology play a crucial role in flight safety. Even so, international legislation is vague relative to training requirements in hypoxia and altitude physiology. Based on a previously developed survey, an adapted questionnaire was formulated and released online for Portuguese pilots. Specific questions regarding the need for pilot attention monitoring systems were added to the original survey. There were 117 pilots, 2 of whom were women, who completed the survey. Most of the pilots had a light aviation license and flew in unpressurized cabins at a maximum ceiling of 10,000 ft (3048 m). The majority of the respondents never experienced hypoxic symptoms. In general, most of the individuals agreed with the importance of an introductory hypoxia course without altitude chamber training (ACT) for all pilot populations, and with a pilot monitoring system in order to increase flight safety. Generally, most of the pilots felt that hypoxia education and training for unpressurized aircraft is not extensive enough. However, almost all the respondents were willing to use a flight physiology monitoring system in order to improve flight safety.

Identification of residual leukemic cells by flow cytometry in childhood B-cell precursor acute lymphoblastic leukemia: verification of leukemic state by flow-sorting and molecular/cytogenetic methods.

PubMed

Øbro, Nina F; Ryder, Lars P; Madsen, Hans O; Andersen, Mette K; Lausen, Birgitte; Hasle, Henrik; Schmiegelow, Kjeld; Marquart, Hanne V

2012-01-01

Reduction in minimal residual disease, measured by real-time quantitative PCR or flow cytometry, predicts prognosis in childhood B-cell precursor acute lymphoblastic leukemia. We explored whether cells reported as minimal residual disease by flow cytometry represent the malignant clone harboring clone-specific genomic markers (53 follow-up bone marrow samples from 28 children with B-cell precursor acute lymphoblastic leukemia). Cell populations (presumed leukemic and non-leukemic) were flow-sorted during standard flow cytometry-based minimal residual disease monitoring and explored by PCR and/or fluorescence in situ hybridization. We found good concordance between flow cytometry and genomic analyses in the individual flow-sorted leukemic (93% true positive) and normal (93% true negative) cell populations. Four cases with discrepant results had plausible explanations (e.g. partly informative immunophenotype and antigen modulation) that highlight important methodological pitfalls. These findings demonstrate that with sufficient experience, flow cytometry is reliable for minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia, although rare cases require supplementary PCR-based monitoring.

Use of Twitter to monitor attitudes toward depression and schizophrenia: an exploratory study

PubMed Central

Pilkington, Pamela D.

2014-01-01

Introduction. The paper reports on an exploratory study of the usefulness of Twitter for unobtrusive assessment of stigmatizing attitudes in the community. Materials and Methods. Tweets with the hashtags #depression or #schizophrenia posted on Twitter during a 7-day period were collected. Tweets were categorised based on their content and user information and also on the extent to which they indicated a stigmatising attitude towards depression or schizophrenia (stigmatising, personal experience of stigma, supportive, neutral, or anti-stigma). Tweets that indicated stigmatising attitudes or personal experiences of stigma were further grouped into the following subthemes: social distance, dangerousness, snap out of it, personal weakness, inaccurate beliefs, mocking or trivializing, and self-stigma. Results and Discussion. Tweets on depression mostly related to resources for consumers (34%), or advertised services or products for individuals with depression (20%). The majority of schizophrenia tweets aimed to increase awareness of schizophrenia (29%) or reported on research findings (22%). Tweets on depression were largely supportive (65%) or neutral (27%). A number of tweets were specifically anti-stigma (7%). Less than 1% of tweets reflected stigmatising attitudes (0.7%) or personal experience of stigma (0.1%). More than one third of the tweets which reflected stigmatising attitudes were mocking or trivialising towards individuals with depression (37%). The attitude that individuals with depression should “snap out of it” was evident in 30% of the stigmatising tweets. The majority of tweets relating to schizophrenia were categorised as supportive (42%) or neutral (43%). Almost 10% of tweets were explicitly anti-stigma. The percentage of tweets showing stigmatising attitudes was 5%, while less than 1% of tweets described personal experiences of stigmatising attitudes towards individuals with schizophrenia. Of the tweets that indicated stigmatising attitudes, most reflected inaccurate beliefs about schizophrenia being multiple personality disorder (52%) or mocked or trivialised individuals with schizophrenia (33%). Conclusions. The study supports the use of analysis of Twitter content to unobtrusively measure attitudes towards mental illness, both supportive and stigmatising. The results of the study may be useful in assisting mental health promotion and advocacy organisations to provide information about resources and support, raise awareness and counter common stigmatising attitudes. PMID:25374786

Ambulatory Autonomic Activity Monitoring Among At-Risk Adolescent Mothers

PubMed Central

Rajan, Sonali; Leonard, Noelle; Fletcher, Richard; Casarjian, Beth; Casarjian, Robin; Cisse, Cathleen; Gwadz, Marya

2013-01-01

Background Many adolescent mothers experience significant challenges in regulating emotions due to adverse life experiences, which can place adolescent mothers and their children at risk for poor developmental outcomes. Ambulatory monitoring of stress that also provides immediate feedback using wearable biosensors has the potential to enhance clinician-delivered parenting interventions and help young mothers develop emotion regulatory skills. Methods We conducted a pilot study to assess the acceptability, ease of use, and preliminary efficacy of a wearable biosensor, the iCalm sensor band, among a sample of four mothers, ages 15–18 years. Mothers wore the biosensor for a period of 24–36 hours while engaging in normal, daily tasks (e.g. caring for their child, attending school). Both quantitative electrodermal activity (EDA) data (via the iCalm sensor band) and qualitative data (via individual semi-structured interviews) were collected. Results The adolescent mothers were able to comfortably use and wear the iCalm sensor band. EDA data were collected and corresponded with stressful daily life events described by the mothers during qualitative interviews. Conclusion The iCalm biosensor is acceptable to use among high-risk adolescent mothers and appears to help mothers with the development of emotion regulatory skills. PMID:23626657

A low temperature furnace for solution crystal growth on the International Space Station

NASA Astrophysics Data System (ADS)

Baç, Nurcan; Harpster, Joseph; Maston, Robert A.; Sacco, Albert

2000-01-01

The Zeolite Crystal Growth Furnace Unit (ZCG-FU) is the first module in an integrated payload designed for low temperature crystal growth in solutions on the International Space Station (ISS). This payload is scheduled to fly on the ISS flight 7A.1 in an EXPRESS rack. Its name originated from early shuttle flight experiments limited to the growth of zeolite crystals but has since grown to include other materials of significant commercial interest using the solution method of crystal growth. Zeolites, ferroelectrics, piezeoelectrics and silver halides are some of the materials considered. The ZCG-FU experiment consists of a furnace unit and its electronic control system, and mechanically complex, crystal growth autoclaves suitable for use with a particular furnace and solution. The ZCG facility is being designed to grow into four independent furnaces controlled by IZECS (Improved Zeolite Electronic Control System). IZECS provides monitoring of critical parameters, data logging, safety monitoring, air-to-ground control and operator interfacing. It is suitable for controlling the four furnaces either individually or all at one time. It also contains the power management solid-state drivers and switches for the ZCG-FU furnace. The furnace contains 19 tubes operating at three different temperature zones. .

Functional connectivity experiments reflect routine movement behavior of a tropical hummingbird species.

PubMed

Volpe, Noelia L; Hadley, Adam S; Robinson, W Douglas; Betts, Matthew G

Translocation experiments, in which researchers displace animals and then monitor their movements to return home, are commonly used as tools to assess functional connectivity of fragmented landscapes. Such experiments are purported to have important advantages of being time efficient and of standardizing “motivation” to move across individuals. Yet, we lack tests of whether movement behavior of translocated birds reflects natural behavior of unmanipulated birds. We compared the routine movement behavior of a tropical hummingbird, the Green Hermit (Phaethornis guy), to that of experimentally translocated individuals. We tested for differences in site selection patterns during movement at two spatial scales (point and path levels). We also compared movement rates between treatments. Behaviors documented during translocation experiments reflected those observed during routine movements. At the point level, both translocated and non-translocated birds showed similar levels of preference for mature tropical forest. At the path level, step selection functions showed both translocated and non-translocated hummingbirds avoiding movement across non-forested matrix and selecting streams as movement corridors. Movement rates were generally higher during translocation experiments. However, the negative influence of forest cover on movement rates was proportionately similar in translocation and routine movement treatments. We report the first evidence showing that movement behavior of birds during translocation experiments is similar to their natural movement behavior. Therefore, translocation experiments may be reliable tools to address effects of landscape structure on animal movement. We observed consistent selection of landscape elements between translocated and non-translocated birds, indicating that both routine and translocation movement studies lead to similar conclusions regarding the effect of landscape structure and forest composition on functional connectivity. Our observation that hummingbirds avoid non-forest matrix and select riparian corridors also provides a potential mechanism for pollen limitation in fragmented tropical forest.

Realtime monitoring of bridge scour using remote monitoring technology

DOT National Transportation Integrated Search

2011-02-01

The research performed in this project focuses on the application of instruments including accelerometers : and tiltmeters to monitor bridge scour. First, two large scale laboratory experiments were performed. One : experiment is the simulation of a ...

The double stigma of obesity and serious mental illnesses: promoting health and recovery.

PubMed

Mizock, Lauren

2012-12-01

This article contrasts the traditional medical approach and size acceptance perspectives on obesity among people with serious mental illnesses. Higher incidences of obesity among populations with serious mental illnesses have been identified. In response, a recent initiative in mental health has urged providers to address the obesity rates among populations with mental illnesses by monitoring weight, prescribing weight loss medication, and recommending bariatric surgery. However, literature is emerging with regards to the double stigma experienced by individuals with obesity and a mental illness. Therefore, the traditional focus on weight loss can benefit from a size acceptance approach to focus on health promotion and avoid stigmatizing size. Citations of theoretical and behavioral health literature on the experiences of individuals with mental illnesses and obesity are presented. Recommendations for interventions, training, and future research related to obesity and mental illnesses are provided. Implications are suggested for a size acceptance approach to interventions for individuals in recovery from mental illnesses to promote health at every size within mental health and medical settings.

Keeping your distance: attentional withdrawal in individuals who show physiological signs of social discomfort.

PubMed

Szpak, Ancret; Loetscher, Tobias; Churches, Owen; Thomas, Nicole A; Spence, Charles J; Nicholls, Michael E R

2015-04-01

Being in close social proximity to a stranger is generally perceived to be an uncomfortable experience, which most people seek to avoid. In circumstances where crowding is unavoidable, however, people may seek to withdraw their attention from the other person. This study examined whether social discomfort, as indexed by electrodermal activity, is related to a withdrawal of attention in 28 (m=8, f=20) university students. Students performed a radial line bisection task while alone or together with a stranger facing them. Physiological arousal was indexed by a wrist monitor, which recorded electrodermal activity. Correlational analyses showed that individuals who displayed physiological discomfort when together showed a withdrawal of the perceived midpoint of the line towards them (and away from the stranger). Conversely, individuals who showed no discomfort exhibited an expansion of the perceived midpoint away from them. We propose that participants shift their attention away from the stranger to increase interpersonal distance and reduce anxiety/arousal. Copyright © 2014 Elsevier Ltd. All rights reserved.

Telomere dynamics in wild brown trout: effects of compensatory growth and early growth investment.

PubMed

Näslund, Joacim; Pauliny, Angela; Blomqvist, Donald; Johnsson, Jörgen I

2015-04-01

After a period of food deprivation, animals often respond with a period of faster than normal growth. Such responses have been suggested to result in decreased chromosomal maintenance, which in turn may affect the future fitness of an individual. Here, we present a field experiment in which a food deprivation period of 24 days was enforced on fish from a natural population of juvenile brown trout (Salmo trutta) at the start of the high-growth season in spring. The growth of the food-deprived fish and a non-deprived control group was then monitored in the wild during 1 year. Fin tissue samples were taken at the start of the experiment and 1 year after food deprivation to monitor the telomere dynamics, using reduced telomere length as an indicator of maintenance cost. The food-deprived fish showed partial compensatory growth in both mass and length relative to the control group. However, we found no treatment effects on telomere dynamics, suggesting that growth-compensating brown trout juveniles are able to maintain their telomeres during their second year in the stream. However, body size at the start of the experiment, reflecting growth rate during their first year of life, was negatively correlated with change in telomere length over the following year. This result raises the possibility that rapid growth early in life induces delayed costs in cellular maintenance.

Aspects of operational radiation protection during dismantling of nuclear facilities relevant for the estimation of internal doses.

PubMed

Labarta, T

2007-01-01

Operational radiation protection of workers during the dismantling of nuclear facilities is based on the same radiation protection principles as that applied in its exploitation period with the objective of ensuring proper implementation of the as-low-as-reasonably-achievable (ALARA) principle. These principles are: prior determination of the nature and magnitude of radiological risk; classification of workplaces and workers depending on the risks; implementation of control measures; monitoring of zones and working conditions, including, if necessary, individual monitoring. From the experiences and the lessons learned during the dismantling processes carried out in Spain, several important aspects in the practical implementation of these principles that directly influence and ensure an adequate prevention of exposures and the estimation of internal doses are pointed out, with special emphasis on the estimation of internal doses due to transuranic intakes.

Challenges for Better thesis supervision.

PubMed

Ghadirian, Laleh; Sayarifard, Azadeh; Majdzadeh, Reza; Rajabi, Fatemeh; Yunesian, Masoud

2014-01-01

Conduction of thesis by the students is one of their major academic activities. Thesis quality and acquired experiences are highly dependent on the supervision. Our study is aimed at identifing the challenges in thesis supervision from both students and faculty members point of view. This study was conducted using individual in-depth interviews and Focus Group Discussions (FGD). The participants were 43 students and faculty members selected by purposive sampling. It was carried out in Tehran University of Medical Sciences in 2012. Data analysis was done concurrently with data gathering using content analysis method. Our data analysis resulted in 162 codes, 17 subcategories and 4 major categories, "supervisory knowledge and skills", "atmosphere", "bylaws and regulations relating to supervision" and "monitoring and evaluation". This study showed that more attention and planning in needed for modifying related rules and regulations, qualitative and quantitative improvement in mentorship training, research atmosphere improvement and effective monitoring and evaluation in supervisory area.

The emotive nature of conflict monitoring in the medial prefrontal cortex.

PubMed

Saunders, Blair; Lin, Hause; Milyavskaya, Marina; Inzlicht, Michael

2017-09-01

The detection of conflict between incompatible impulses, thoughts, and actions is a ubiquitous source of motivation across theories of goal-directed action. In this overview, we explore the hypothesis that conflict is emotive, integrating perspectives from affective science and cognitive neuroscience. Initially, we review evidence suggesting that the mental and biological processes that monitor for information processing conflict-particularly those generated by the anterior midcingulate cortex-track the affective significance of conflict and use this signal to motivate increased control. In this sense, variation in control resembles a form of affect regulation in which control implementation counteracts the aversive experience of conflict. We also highlight emerging evidence proposing that states and dispositions associated with acceptance facilitate control by tuning individuals to the emotive nature of conflict, before proposing avenues for future research, including investigating the role of affect in reinforcement learning and decision making. Copyright © 2017 Elsevier B.V. All rights reserved.

Challenges for Better thesis supervision

PubMed Central

Ghadirian, Laleh; Sayarifard, Azadeh; Majdzadeh, Reza; Rajabi, Fatemeh; Yunesian, Masoud

2014-01-01

Background: Conduction of thesis by the students is one of their major academic activities. Thesis quality and acquired experiences are highly dependent on the supervision. Our study is aimed at identifing the challenges in thesis supervision from both students and faculty members point of view. Methods: This study was conducted using individual in-depth interviews and Focus Group Discussions (FGD). The participants were 43 students and faculty members selected by purposive sampling. It was carried out in Tehran University of Medical Sciences in 2012. Data analysis was done concurrently with data gathering using content analysis method. Results: Our data analysis resulted in 162 codes, 17 subcategories and 4 major categories, "supervisory knowledge and skills", "atmosphere", "bylaws and regulations relating to supervision" and "monitoring and evaluation". Conclusion: This study showed that more attention and planning in needed for modifying related rules and regulations, qualitative and quantitative improvement in mentorship training, research atmosphere improvement and effective monitoring and evaluation in supervisory area. PMID:25250273

Effects of Relocation and Individual and Environmental Factors on the Long-Term Stress Levels in Captive Chimpanzees (Pan troglodytes): Monitoring Hair Cortisol and Behaviors.

PubMed

Yamanashi, Yumi; Teramoto, Migaku; Morimura, Naruki; Hirata, Satoshi; Inoue-Murayama, Miho; Idani, Gen'ichi

2016-01-01

Understanding the factors associated with the long-term stress levels of captive animals is important from the view of animal welfare. In this study, we investigated the effects of relocation in addition to individual and environmental factors related to social management on long-term stress level in group-living captive chimpanzees by examining behaviors and hair cortisol (HC). Specifically, we conducted two studies. The first compared changes in HC levels before and after the relocation of 8 chimpanzees (Study 1) and the second examined the relationship between individual and environmental factors and individual HC levels in 58 chimpanzees living in Kumamoto Sanctuary (KS), Kyoto University (Study 2). We hypothesized that relocation, social situation, sex, and early rearing conditions, would affect the HC levels of captive chimpanzees. We cut arm hair from chimpanzees and extracted and assayed cortisol with an enzyme immunoassay. Aggressive behaviors were recorded ad libitum by keepers using a daily behavior monitoring sheet developed for this study. The results of Study 1 indicate that HC levels increased during the first year after relocation to the new environment and then decreased during the second year. We observed individual differences in reactions to relocation and hypothesized that social factors may mediate these changes. In Study 2, we found that the standardized rate of receiving aggression, rearing history, sex, and group formation had a significant influence on mean HC levels. Relocation status was not a significant factor, but mean HC level was positively correlated with the rate of receiving aggression. Mean HC levels were higher in males than in females, and the association between aggressive interactions and HC levels differed by sex. These results suggest that, although relocation can affect long-term stress level, individuals' experiences of aggression and sex may be more important contributors to long-term stress than relocation alone.

Social Monitoring Matters for Deterring Social Deviance in Stable but Not Mobile Socio-Ecological Contexts

PubMed Central

Su, Jenny C.; Chiu, Chi-Yue; Lin, Wei-Fang; Oishi, Shigehiro

2016-01-01

Previous research suggests that reputational concerns can incentivize cooperation and deter socially deviant behavior. The current research showed that social monitoring of information that has the potential to damage one’s reputation has differential effects on deviant behavior in social-ecological environments that vary in level of mobility. Study 1 showed that residentially stable cities that employed more journalists—who can be regarded as social monitoring agents in a community—tended to have lower rates of violent crime than residentially stable cities that employed fewer journalists; by contrast, in residentially mobile cities, violent crime rates did not vary as a function of the number of journalists employed. In Study 2, we found that individual differences in perceptions of relational mobility moderated the effects of social monitoring on cheating in a die-under-cup game. Specifically, social monitoring cues reduced the likelihood of cheating but only among participants who perceived their immediate social environment to be low in relational mobility. The same results were replicated in Study 3, an experiment in which participants’ perception of relational mobility was manipulated before completing an online maze game that allowed them to earn extra cash. In the low mobility condition, the percentage of participants who continued working on the mazes after reaching the time limit decreased as a function of social monitoring; however, this pattern was not observed in the high mobility condition. Together, our findings suggest that socioecological context matters for understanding effective mechanisms of social control. PMID:27880826

Brief Mindfulness Meditation Training Reduces Mind-Wandering: The Critical Role of Acceptance

PubMed Central

Rahl, Hayley A.; Lindsay, Emily K.; Pacilio, Laura E.; Brown, Kirk W.; Creswell, J. David

2016-01-01

Mindfulness meditation programs, which train individuals to monitor their present moment experience in an open or accepting way, have been shown to reduce mind-wandering on standardized tasks in several studies. Here we test two competing accounts for how mindfulness training reduces mind-wandering, evaluating whether the attention monitoring component of mindfulness training alone reduces mind-wandering or whether the acceptance training component is necessary for reducing mind-wandering. Healthy young adults (N=147) were randomized to either a 3-day brief mindfulness training condition incorporating instruction in both attention monitoring and acceptance, a mindfulness training condition incorporating attention monitoring instruction only, a relaxation training condition, or a reading control condition. Participants completed measures of dispositional mindfulness and treatment expectancies before the training session on Day 1 and then completed a 6-minute Sustained Attention Response Task (SART) measuring mind-wandering after the training session on Day 3. Acceptance training was important for reducing mind-wandering, such that the monitoring + acceptance mindfulness training condition had the lowest mind-wandering relative to the other conditions, including significantly lower mind-wandering relative to the monitor-only mindfulness training condition. In one of the first experimental mindfulness training dismantling studies to-date, we show that training in acceptance is a critical driver of mindfulness training reductions in mind-wandering. This effect suggests that acceptance skills may facilitate emotion regulation on boring and frustrating sustained attention tasks that foster mind-wandering, such as the SART. PMID:27819445

Social Monitoring Matters for Deterring Social Deviance in Stable but Not Mobile Socio-Ecological Contexts.

PubMed

Su, Jenny C; Chiu, Chi-Yue; Lin, Wei-Fang; Oishi, Shigehiro

2016-01-01

Previous research suggests that reputational concerns can incentivize cooperation and deter socially deviant behavior. The current research showed that social monitoring of information that has the potential to damage one's reputation has differential effects on deviant behavior in social-ecological environments that vary in level of mobility. Study 1 showed that residentially stable cities that employed more journalists-who can be regarded as social monitoring agents in a community-tended to have lower rates of violent crime than residentially stable cities that employed fewer journalists; by contrast, in residentially mobile cities, violent crime rates did not vary as a function of the number of journalists employed. In Study 2, we found that individual differences in perceptions of relational mobility moderated the effects of social monitoring on cheating in a die-under-cup game. Specifically, social monitoring cues reduced the likelihood of cheating but only among participants who perceived their immediate social environment to be low in relational mobility. The same results were replicated in Study 3, an experiment in which participants' perception of relational mobility was manipulated before completing an online maze game that allowed them to earn extra cash. In the low mobility condition, the percentage of participants who continued working on the mazes after reaching the time limit decreased as a function of social monitoring; however, this pattern was not observed in the high mobility condition. Together, our findings suggest that socioecological context matters for understanding effective mechanisms of social control.

Fast by Nature - How Stress Patterns Define Human Experience and Performance in Dexterous Tasks

PubMed Central

Pavlidis, I.; Tsiamyrtzis, P.; Shastri, D.; Wesley, A.; Zhou, Y.; Lindner, P.; Buddharaju, P.; Joseph, R.; Mandapati, A.; Dunkin, B.; Bass, B.

2012-01-01

In the present study we quantify stress by measuring transient perspiratory responses on the perinasal area through thermal imaging. These responses prove to be sympathetically driven and hence, a likely indicator of stress processes in the brain. Armed with the unobtrusive measurement methodology we developed, we were able to monitor stress responses in the context of surgical training, the quintessence of human dexterity. We show that in dexterous tasking under critical conditions, novices attempt to perform a task's step equally fast with experienced individuals. We further show that while fast behavior in experienced individuals is afforded by skill, fast behavior in novices is likely instigated by high stress levels, at the expense of accuracy. Humans avoid adjusting speed to skill and rather grow their skill to a predetermined speed level, likely defined by neurophysiological latency. PMID:22396852

LACIE - A look to the future. [Large Area Crop Inventory Experiment

NASA Technical Reports Server (NTRS)

Macdonald, R. B.; Hall, F. G.

1977-01-01

The Large Area Crop Inventory Experiment (LACIE) is a 'proof of concept' project designed to demonstrate the applicability of remote sensing technology to the global monitoring of wheat. This paper discusses the need for more timely and reliable monitoring of food and fiber supplies, reviews the monitoring systems currently utilized by the USDA and United Nations Food and Agriculture Organization in the United States and in foreign countries, and elucidates the fundamentals involved in assessing the impact of variable weather and economic conditions on wheat acreage, yield, and production. The experiment's approach to production monitoring is described briefly, and its status is reviewed as of the conclusion of 2 years of successful operation. Examples of acreage and yield monitoring in the Soviet Union are used to illustrate the experiment's approach.

Network Monitor and Control of Disruption-Tolerant Networks

NASA Technical Reports Server (NTRS)

Torgerson, J. Leigh

2014-01-01

For nearly a decade, NASA and many researchers in the international community have been developing Internet-like protocols that allow for automated network operations in networks where the individual links between nodes are only sporadically connected. A family of Disruption-Tolerant Networking (DTN) protocols has been developed, and many are reaching CCSDS Blue Book status. A NASA version of DTN known as the Interplanetary Overlay Network (ION) has been flight-tested on the EPOXI spacecraft and ION is currently being tested on the International Space Station. Experience has shown that in order for a DTN service-provider to set up a large scale multi-node network, a number of network monitor and control technologies need to be fielded as well as the basic DTN protocols. The NASA DTN program is developing a standardized means of querying a DTN node to ascertain its operational status, known as the DTN Management Protocol (DTNMP), and the program has developed some prototypes of DTNMP software. While DTNMP is a necessary component, it is not sufficient to accomplish Network Monitor and Control of a DTN network. JPL is developing a suite of tools that provide for network visualization, performance monitoring and ION node control software. This suite of network monitor and control tools complements the GSFC and APL-developed DTN MP software, and the combined package can form the basis for flight operations using DTN.

Self-monitoring of blood glucose in diabetes mellitus: arguments for an individualized approach.

PubMed

Nauck, Michael A; El-Ouaghlidi, Andrea; Vardarli, Irfan

2009-09-01

The utility of glucose self-monitoring in different types and stages of diabetes is controversial, as there is only sparse relevant evidence from randomized controlled clinical trials. In this analysis, the authors aim to develop individualized recommendations based on clinical needs and the available literature. The PubMed database was searched for articles that appeared up to 30 September 2008 containing the terms "measurement," "control","monitoring," and "hypoglycemia"; the retrieved articles were supplemented by other articles that were cited in them. A directed search was also made for the recommendations of the German, European, American, and international diabetological societies. Conclusions were then drawn about the useful modalities and extent of glucose self-monitoring on the basis of the clinical features of the major types of diabetes and the main treatment strategies for them. With the exception of intensified treatment strategies (which rely on blood-sugar regulation with insulin), only a few evidence-based recommendations can be derived from randomized clinical trials and meta-analyses. Nonetheless, a strategy for self-monitoring according to the patient's individual needs can be derived from the characteristics of therapeutic regimens: depending on the type of diabetes from which the patient suffers, the predicted number of glucometer strips required for self-monitoring will vary from almost none to roughly 400 per month. The decision to use glucose self-monitoring, as well as the type and extent of self-monitoring that will be used, should be based on the individual patient's type of diabetes, treatment regimen, and clinical characteristics. Like any other type of therapeutic intervention, self-monitoring should have a well-documented, rational justification.

Integrating and Visualizing Tropical Cyclone Data Using the Real Time Mission Monitor

NASA Technical Reports Server (NTRS)

Goodman, H. Michael; Blakeslee, Richard; Conover, Helen; Hall, John; He, Yubin; Regner, Kathryn

2009-01-01

The Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the NASA Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery, radar, surface and airborne instrument data sets, model output parameters, lightning location observations, aircraft navigation data, soundings, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual globe application. RTMM is extremely valuable for optimizing individual Earth science airborne field experiments. Flight planners, scientists, and managers appreciate the contributions that RTMM makes to their flight projects. A broad spectrum of interdisciplinary scientists used RTMM during field campaigns including the hurricane-focused 2006 NASA African Monsoon Multidisciplinary Analyses (NAMMA), 2007 NOAA-NASA Aerosonde Hurricane Noel flight, 2007 Tropical Composition, Cloud, and Climate Coupling (TC4), plus a soil moisture (SMAP-VEX) and two arctic research experiments (ARCTAS) in 2008. Improving and evolving RTMM is a continuous process. RTMM recently integrated the Waypoint Planning Tool, a Java-based application that enables aircraft mission scientists to easily develop a pre-mission flight plan through an interactive point-and-click interface. Individual flight legs are automatically calculated "on the fly". The resultant flight plan is then immediately posted to the Google Earth-based RTMM for interested scientists to view the planned flight track and subsequently compare it to the actual real time flight progress. We are planning additional capabilities to RTMM including collaborations with the Jet Propulsion Laboratory in the joint development of a Tropical Cyclone Integrated Data Exchange and Analysis System (TC IDEAS) which will serve as a web portal for access to tropical cyclone data, visualizations and model output.

2005 Annual Health Physics Report for HEU Transparency Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Radev, R

2006-04-21

During the 2005 calendar year, LLNL provided health physics support for the Highly Enriched Uranium Transparency Program (HEU-TP) in external and internal radiation protection and technical expertise into matters related to BDMS radioactive sources and Russian radiation safety regulatory compliance. For the calendar year 2005, there were 161 person-trips that required dose monitoring of the U.S. monitors. Of the 161 person-trips, 149 person-trips were SMVs and 12 person-trips were Transparency Monitoring Office (TMO) trips. Additionally, there were 11 monitoring visits by TMO monitors to facilities other than UEIE and 3 to UEIE itself. There were two monitoring visits (source changes)more » that were back to back with 16 monitors. Each of these concurring visits were treated as single person-trips for dosimetry purposes. Counted individually, there were 191 individual person-visits in 2005. The LLNL Safety Laboratories Division provided the dosimetry services for the HEU-TP monitors.« less

Vibration-based monitoring for performance evaluation of flexible civil structures in Japan.

PubMed

Fujino, Yozo

2018-01-01

The vibration-based monitoring of flexible civil structures and performance evaluation from this monitoring are reviewed, with an emphasis on research and practice in Japan and the author's experiences. Some new findings and unexpected vibrations from the monitoring of real bridges and buildings are reported to emphasize the importance of monitoring. Future developments and applications of vibration-based monitoring to civil infrastructure management are also described. Many examples are taken from the author's past 30 years' experience of research on bridge dynamics.

Trigger Menu-aware Monitoring for the ATLAS experiment

NASA Astrophysics Data System (ADS)

Hoad, Xanthe; ATLAS Collaboration

2017-10-01

We present a“trigger menu-aware” monitoring system designed for the Run-2 data-taking of the ATLAS experiment at the LHC. Unlike Run-1, where a change in the trigger menu had to be matched by the installation of a new software release at Tier-0, the new monitoring system aims to simplify the ATLAS operational workflows. This is achieved by integrating monitoring updates in a quick and flexible manner via an Oracle DB interface. We present the design and the implementation of the menu-aware monitoring, along with lessons from the operational experience of the new system with the 2016 collision data.

Selective stimulation of facial muscles with a penetrating electrode array in the feline model

PubMed Central

Sahyouni, Ronald; Bhatt, Jay; Djalilian, Hamid R.; Tang, William C.; Middlebrooks, John C.; Lin, Harrison W.

2017-01-01

Objective Permanent facial nerve injury is a difficult challenge for both patients and physicians given its potential for debilitating functional, cosmetic, and psychological sequelae. Although current surgical interventions have provided considerable advancements in facial nerve rehabilitation, they often fail to fully address all impairments. We aim to introduce an alternative approach to facial nerve rehabilitation. Study design Acute experiments in animals with normal facial function. Methods The study included three anesthetized cats. Four facial muscles (levator auris longus, orbicularis oculi, nasalis, and orbicularis oris) were monitored with a standard electromyographic (EMG) facial nerve monitoring system with needle electrodes. The main trunk of the facial nerve was exposed and a 16-channel penetrating electrode array was placed into the nerve. Electrical current pulses were delivered to each stimulating electrode individually. Elicited EMG voltage outputs were recorded for each muscle. Results Stimulation through individual channels selectively activated restricted nerve populations, resulting in selective contraction of individual muscles. Increasing stimulation current levels resulted in increasing EMG voltage responses. Typically, selective activation of two or more distinct muscles was successfully achieved via a single placement of the multi-channel electrode array by selection of appropriate stimulation channels. Conclusion We have established in the animal model the ability of a penetrating electrode array to selectively stimulate restricted fiber populations within the facial nerve and to selectively elicit contractions in specific muscles and regions of the face. These results show promise for the development of a facial nerve implant system. PMID:27312936

Institutional racism in public health contracting: Findings of a nationwide survey from New Zealand.

PubMed

Came, H; Doole, C; McKenna, B; McCreanor, T

2018-02-01

Public institutions within New Zealand have long been accused of mono-culturalism and institutional racism. This study sought to identify inconsistencies and bias by comparing government funded contracting processes for Māori public health providers (n = 60) with those of generic providers (n = 90). Qualitative and quantitative data were collected (November 2014-May 2015), through a nationwide telephone survey of public health providers, achieving a 75% response rate. Descriptive statistical analyses were applied to quantitative responses and an inductive approach was taken to analyse data from open-ended responses in the survey domains of relationships with portfolio contract managers, contracting and funding. The quantitative data showed four sites of statistically significant variation: length of contracts, intensity of monitoring, compliance costs and frequency of auditing. Non-significant data involved access to discretionary funding and cost of living adjustments, the frequency of monitoring, access to Crown (government) funders and representation on advisory groups. The qualitative material showed disparate provider experiences, dependent on individual portfolio managers, with nuanced differences between generic and Māori providers' experiences. This study showed that monitoring government performance through a nationwide survey was an innovative way to identify sites of institutional racism. In a policy context where health equity is a key directive to the health sector, this study suggests there is scope for New Zealand health funders to improve their contracting practices. Copyright © 2017 Elsevier Ltd. All rights reserved.

Design of integrated ship monitoring system using SAR, RADAR, and AIS

NASA Astrophysics Data System (ADS)

Yang, Chan-Su; Kim, Tae-Ho; Hong, Danbee; Ahn, Hyung-Wook

2013-06-01

When we talk about for the ship detection, identification and its classification, we need to go for the wide area of monitoring and it may be possible only through satellite based monitoring approach which monitors and covers coastal as well as the oceanic zone. Synthetic aperture radar (SAR) has been widely used to detect targets of interest with the advantage of the operating capability in all weather and luminance free condition (Margarit and Tabasco, 2011). In EU waters, EMSA(European Maritime Safety Agency) is operating the SafeSeaNet and CleanSeaNet systems which provide the current positions of all ships and oil spill monitoring information in and around EU waters in a single picture to Member States using AIS, LRIT and SAR images. In many countries, a similar system has been developed and the key of the matter is to integrate all available data. This abstract describes the preliminary design concept for an integration system of RADAR, AIS and SAR data for vessel traffic monitoring. SAR sensors are used to acquire image data over large coverage area either through the space borne or airborne platforms in UTC. AIS reports should be also obtained on the same date as of the SAR acquisition for the purpose to perform integration test. Land-based RADAR can provide ships positions detected and tracked in near real time. In general, SAR are used to acquire image data over large coverage area, AIS reports are obtained from ship based transmitter, and RADAR can monitor continuously ships for a limited area. In this study, we developed individual ship monitoring algorithms using RADAR(FMCW and Pulse X-band), AIS and SAR(RADARSAT-2 Full-pol Mode). We conducted field experiments two times for displaying the RADAR, AIS and SAR integration over the Pyeongtaek Port, South Korea.

Tracking motor units longitudinally across experimental sessions with high‐density surface electromyography

PubMed Central

Martinez‐Valdes, E.; Negro, F.; Laine, C. M.; Falla, D.; Mayer, F.

2017-01-01

Key points Classic motor unit (MU) recording and analysis methods do not allow the same MUs to be tracked across different experimental sessions, and therefore, there is limited experimental evidence on the adjustments in MU properties following training or during the progression of neuromuscular disorders.We propose a new processing method to track the same MUs across experimental sessions (separated by weeks) by using high‐density surface electromyography.The application of the proposed method in two experiments showed that individual MUs can be identified reliably in measurements separated by weeks and that changes in properties of the tracked MUs across experimental sessions can be identified with high sensitivity.These results indicate that the behaviour and properties of the same MUs can be monitored across multiple testing sessions.The proposed method opens new possibilities in the understanding of adjustments in motor unit properties due to training interventions or the progression of pathologies. Abstract A new method is proposed for tracking individual motor units (MUs) across multiple experimental sessions on different days. The technique is based on a novel decomposition approach for high‐density surface electromyography and was tested with two experimental studies for reliability and sensitivity. Experiment I (reliability): ten participants performed isometric knee extensions at 10, 30, 50 and 70% of their maximum voluntary contraction (MVC) force in three sessions, each separated by 1 week. Experiment II (sensitivity): seven participants performed 2 weeks of endurance training (cycling) and were tested pre–post intervention during isometric knee extensions at 10 and 30% MVC. The reliability (Experiment I) and sensitivity (Experiment II) of the measured MU properties were compared for the MUs tracked across sessions, with respect to all MUs identified in each session. In Experiment I, on average 38.3% and 40.1% of the identified MUs could be tracked across two sessions (1 and 2 weeks apart), for the vastus medialis and vastus lateralis, respectively. Moreover, the properties of the tracked MUs were more reliable across sessions than those of the full set of identified MUs (intra‐class correlation coefficients ranged between 0.63—0.99 and 0.39–0.95, respectively). In Experiment II, ∼40% of the MUs could be tracked before and after the training intervention and training‐induced changes in MU conduction velocity had an effect size of 2.1 (tracked MUs) and 1.5 (group of all identified motor units). These results show the possibility of monitoring MU properties longitudinally to document the effect of interventions or the progression of neuromuscular disorders. PMID:28032343

Modulation of the conflict monitoring intensity: the role of aversive reinforcement, cognitive demand, and trait-BIS.

PubMed

Leue, Anja; Lange, Sebastian; Beauducel, André

2012-06-01

According to Botvinick's (2007) integrative account, conflict monitoring is aversive because individuals anticipate cognitive demand, whereas the revised reinforcement sensitivity theory (rRST) predicts that conflict processing is aversive because individuals anticipate aversive reinforcement of erroneous responses. Because these accounts give different reasons for the aversive aspects of conflict, we manipulated cognitive demand and the aversive reinforcement as a consequence of wrong choices in a go/no-go task. Thereby, we also aimed to investigate whether individual differences in conflict sensitivity (i.e., in trait anxiety, linked to high sensitivity of the behavioral inhibition system [trait-BIS]) represent the effects of aversive reinforcement and cognitive demand in conflict tasks. We expected that these manipulations would have effects on the frontal N2 component representing activity of the anterior cingulate cortex. Moreover, higher-trait-BIS individuals should be more sensitive than lower-trait-BIS individuals to aversive effects in conflict situations, resulting in a more negative frontal N2 for higher-trait-BIS individuals. In Study 1, with N = 104 students, and Study 2, with N = 47 students, aversive reinforcement was manipulated in three levels (within-subjects factor) and cognitive demand in two levels (between-subjects factor). The behavioral findings from the go/no-go task with noncounterbalanced reinforcement levels (Study 1) could be widely replicated in a task with counterbalanced reinforcement levels (Study 2). The frontal mean no-go N2 amplitude and the frontal no-go N2 dipole captured predicted reinforcement-related variations of conflict monitoring, indicating that the anticipation of aversive reinforcement induces variations in conflict monitoring intensity in frontal brain areas. The aversive nature of conflict was underlined by the more pronounced conflict monitoring in higher- than in lower-trait-BIS individuals.

Monitoring Plant Drought Stress Response Using Terahertz Time-Domain Spectroscopy[C][W

PubMed Central

Born, Norman; Behringer, David; Liepelt, Sascha; Beyer, Sarah; Schwerdtfeger, Michael; Ziegenhagen, Birgit; Koch, Martin

2014-01-01

We present a novel measurement setup for monitoring changes in leaf water status using nondestructive terahertz time-domain spectroscopy (THz-TDS). Previous studies on a variety of plants showed the principal applicability of THz-TDS. In such setups, decreasing leaf water content directly correlates with increasing THz transmission. Our new system allows for continuous, nondestructive monitoring of the water status of multiple individual plants each at the same constant leaf position. It overcomes previous drawbacks, which were mainly due to the necessity of relocating the plants. Using needles of silver fir (Abies alba) seedlings as test subjects, we show that the transmission varies along the main axis of a single needle due to a variation in thickness. Therefore, the relocation of plants during the measuring period, which was necessary in the previous THz-TDS setups, should be avoided. Furthermore, we show a highly significant correlation between gravimetric water content and respective THz transmission. By monitoring the relative change in transmission, we were able to narrow down the permanent wilting point of the seedlings. Thus, we established groups of plants with well-defined levels of water stress that could not be detected visually. This opens up the possibility for a broad range of genetic and physiological experiments. PMID:24501000

Detection of deception: Event-related potential markers of attention and cognitive control during intentional false responses.

PubMed

Gibbons, Henning; Schnuerch, Robert; Wittinghofer, Christina; Armbrecht, Anne-Simone; Stahl, Jutta

2018-06-01

Successful deception requires the coordination of multiple mental processes, such as attention, conflict monitoring, and the regulation of emotion. We employed a simple classification task, assessing ERPs to further investigate the attentional and cognitive control components of (instructed) deception. In Experiment 1, 20 participants repeatedly categorized visually presented names of five animals and five plants. Prior to the experiment, however, each participant covertly selected one animal and one plant for deliberate misclassification. For these critical items, we observed significantly increased response times (RTs), error rates, and amplitudes of three ERP components: anterior P3a indicating the processing of task relevance, medial-frontal negativity reflecting conflict monitoring, and posterior P3b indicating sustained visual attention. In a blind identification of the individual critical words based on a priori defined criteria, an algorithm using two behavioral and two ERP measures combined showed a sensitivity of 0.73 and a specificity of 0.95, thus performing far above chance (0.2/0.2). Experiment 2 used five clothing and five furniture names and successfully replicated the findings of Experiment 1 in 25 new participants. For detection of the critical words, the algorithm from Experiment 1 was reused with only slight adjustments of the ERP time windows. This resulted in a very high detection performance (sensitivity 0.88, specificity 0.94) and significantly outperformed an algorithm based on RT alone. Thus, at least under controlled laboratory conditions, a highly accurate detection of instructed lies via the attentional and cognitive control components is feasible, and benefits strongly from combined behavioral and ERP measures. © 2017 Society for Psychophysiological Research.

Monitoring, metacognition, and executive function: elucidating the role of self-reflection in the development of self-regulation.

PubMed

Lyons, Kristen E; Zelazo, Philip David

2011-01-01

While an abundance of research has investigated the development of the automatic and controlled processes through which individuals control their thoughts, emotions, and actions, less research has emphasized the role of the self in self-regulation. This chapter synthesizes four literatures that have examined the mechanisms through which the individual acts in a managerial role, evaluating the current status of the system and initiating regulatory actions as necessary. Taken together, these literatures (on executive function, error monitoring, metacognition, and uncertainty monitoring) suggest that self-reflection plays a critical role in self-regulation, and that developmental improvements in self-reflection (via increasing levels of conscious awareness and enhanced calibration of monitoring systems) may serve as driving forces underlying developmental improvement (and temperamental individual differences) in children's ability to control their thoughts and actions.

Usage monitoring of electrical devices in a smart home.

PubMed

Rahimi, Saba; Chan, Adrian D C; Goubran, Rafik A

2011-01-01

Profiling the usage of electrical devices within a smart home can be used as a method for determining an occupant's activities of daily living. A nonintrusive load monitoring system monitors the electrical consumption at a single electrical source (e.g., main electric utility service entry) and the operating schedules of individual devices are determined by disaggregating the composite electrical consumption waveforms. An electrical device's load signature plays a key role in nonintrusive load monitoring systems. A load signature is the unique electrical behaviour of an individual device when it is in operation. This paper proposes a feature-based model, using the real power and reactive power as features for describing the load signatures of individual devices. Experimental results for single device recognition for 7 devices show that the proposed approach can achieve 100% classification accuracy with discriminant analysis using Mahalanobis distances.

Enabling Self-Monitoring Data Exchange in Participatory Medicine.

PubMed

Lopez-Campos, Guillermo; Ofoghi, Bahadorreza; Martin-Sanchez, Fernando

2015-01-01

The development of new methods, devices and apps for self-monitoring have enabled the extension of the application of these approaches for consumer health and research purposes. The increase in the number and variety of devices has generated a complex scenario where reporting guidelines and data exchange formats will be needed to ensure the quality of the information and the reproducibility of results of the experiments. Based on the Minimal Information for Self Monitoring Experiments (MISME) reporting guideline we have developed an XML format (MISME-ML) to facilitate data exchange for self monitoring experiments. We have also developed a sample instance to illustrate the concept and a Java MISME-ML validation tool. The implementation and adoption of these tools should contribute to the consolidation of a set of methods that ensure the reproducibility of self monitoring experiments for research purposes.

Strategies for monitoring terrestrial animals and habitats

Treesearch

Richard Holthausen; Raymond L. Czaplewski; Don DeLorenzo; Greg Hayward; Winifred B. Kessler; Pat Manley; Kevin S. McKelvey; Douglas S. Powell; Leonard F. Ruggiero; Michael K. Schwartz; Bea Van Horne; Christina D. Vojta

2005-01-01

This General Technical Report (GTR) addresses monitoring strategies for terrestrial animals and habitats. It focuses on monitoring associated with National Forest Management Act planning and is intended to apply primarily to monitoring efforts that are broader than individual National Forests. Primary topics covered in the GTR are monitoring requirements; ongoing...

Temporal and basin-specific population trends of quagga mussels on soft sediment of a multi-basin reservoir

USGS Publications Warehouse

Caldwell, Timothy J; Rosen, Michael R.; Chandra, Sudeep; Acharya, Kumud; Caires, Andrea M; Davis, Clinton J.; Thaw, Melissa; Webster, Daniel M.

2015-01-01

Invasive quagga (Dreissena bugnesis) and zebra (Dreissena ploymorpha) mussels have rapidly spread throughout North America. Understanding the relationships between environmental variables and quagga mussels during the early stages of invasion will help management strategies and allow researchers to predict patterns of future invasions. Quagga mussels were detected in Lake Mead, NV/AZ in 2007, we monitored early invasion dynamics in 3 basins (Boulder Basin, Las Vegas Bay, Overton Arm) bi-annually from 2008-2011. Mean quagga density increased over time during the first year of monitoring and stabilized for the subsequent two years at the whole-lake scale (8 to 132 individuals·m-2, geometric mean), in Boulder Basin (73 to 875 individuals·m-2), and in Overton Arm(2 to 126 individuals·m-2). In Las Vegas Bay, quagga mussel density was low (9 to 44 individuals·m-2), which was correlated with high sediment metal concentrations and warmer (> 30°C) water temperatures associated with that basin. Carbon content in the sediment increased with depth in Lake Mead and during some sampling periods quagga density was also positively correlated with depth, but more research is required to determine the significance of this interaction. Laboratory growth experiments suggested that food quantity may limit quagga growth in Boulder Basin, indicating an opportunity for population expansion in this basin if primary productivity were to increase, but was not the case in Overton Arm. Overall quagga mussel density in Lake Mead is highly variable and patchy, suggesting that temperature, sediment size, and sediment metal concentrations, and sediment carbon content all contribute to mussel distribution patterns. Quagga mussel density in the soft sediment of Lake Mead expanded during initial colonization, and began to stabilize approximately 3 years after the initial invasion.

Structured scaffolding for reflection and problem solving in diabetes self-management: qualitative study of mobile diabetes detective.

PubMed

Mamykina, Lena; Heitkemper, Elizabeth M; Smaldone, Arlene M; Kukafka, Rita; Cole-Lewis, Heather; Davidson, Patricia G; Mynatt, Elizabeth D; Tobin, Jonathan N; Cassells, Andrea; Goodman, Carrie; Hripcsak, George

2016-01-01

To investigate subjective experiences and patterns of engagement with a novel electronic tool for facilitating reflection and problem solving for individuals with type 2 diabetes, Mobile Diabetes Detective (MoDD). In this qualitative study, researchers conducted semi-structured interviews with individuals from economically disadvantaged communities and ethnic minorities who are participating in a randomized controlled trial of MoDD. The transcripts of the interviews were analyzed using inductive thematic analysis; usage logs were analyzed to determine how actively the study participants used MoDD. Fifteen participants in the MoDD randomized controlled trial were recruited for the qualitative interviews. Usage log analysis showed that, on average, during the 4 weeks of the study, the study participants logged into MoDD twice per week, reported 120 blood glucose readings, and set two behavioral goals. The qualitative interviews suggested that individuals used MoDD to follow the steps of the problem-solving process, from identifying problematic blood glucose patterns, to exploring behavioral triggers contributing to these patterns, to selecting alternative behaviors, to implementing these behaviors while monitoring for improvements in glycemic control. This qualitative study suggested that informatics interventions for reflection and problem solving can provide structured scaffolding for facilitating these processes by guiding users through the different steps of the problem-solving process and by providing them with context-sensitive evidence and practice-based knowledge related to diabetes self-management on each of those steps. This qualitative study suggested that MoDD was perceived as a useful tool in engaging individuals in self-monitoring, reflection, and problem solving. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Cardiovascular Responses to Sexual Activity in Able-Bodied Individuals and Those Living with Spinal Cord Injury.

PubMed

Davidson, Ross; Elliott, Stacy; Krassioukov, Andrei

2016-12-15

Sexuality is an integral part of the human experience and persists in health and disability. The cardiovascular system is crucial to sexual function and can be affected profoundly by spinal cord injury (SCI). The effects of sexual activity on the cardiovascular system in SCI have not been summarized and compared with sexual activity in able-bodied individuals. A keyword search of Embase, PubMed, and Medline was conducted. From 471 retrieved studies for able-bodied individuals, 11 were included that met the strict criteria of medically uncomplicated participants. In the SCI literature, 117 studies were screened, with 18 meeting criteria. In able-bodied persons, sexual activity resulted in modest increases in systolic blood pressure peaking at orgasm (males of 163 mm Hg and females of 142 mm Hg) and returning to baseline shortly afterward. In persons with SCI, results varied from minimal changes to significant elevations in systolic blood pressure because of episodes of autonomic dysreflexia, especially in those with high thoracic and cervical lesions. Peak systolic blood pressure in these individuals was measured to be as high as 325 mm Hg. In the SCI population, more intense stimuli (including penile vibrostimulation and electroejaculation) tended to result in a greater increase in systolic blood pressure compared with self-stimulation. Studies that used continuous versus intermittent monitoring were more likely to report greater changes in systolic blood pressure. In able-bodied persons, sexual activity results in modest increases in blood pressure. In those with SCI, intense stimulation and higher injury levels result in a higher likelihood of autonomic dysreflexia and elevated blood pressure. Because of rapid changes in blood pressure, continuous monitoring is more advantageous than intermittent measurement, because the latter may miss peak values.

Achievement Monitoring of Individually Paced Instruction. Final Report.

ERIC Educational Resources Information Center

Pinsky, Paul D.

A study was made to monitor achievement of individually paced instruction. The project concentrated on designing testing procedures in group paced instructional programs to provide information to student, teachers, parents and administrators which could be used in both a formative and summative evaluation. The three objectives of the project were:…

Tablet Technology to Monitor Physical Education IEP Goals and Benchmarks

ERIC Educational Resources Information Center

Lavay, Barry; Sakai, Joyce; Ortiz, Cris; Roth, Kristi

2015-01-01

The Individual with Disabilities Education Act (IDEA) mandates that all children who are eligible for special education services receive an individualized education program (IEP). Adapted physical education (APE) professionals who teach physical education to children with disabilities are challenged with how to best collect and monitor student…

10 CFR 20.2106 - Records of individual monitoring results.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Records of individual monitoring results. 20.2106 Section 20.2106 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20... includes records required under the standards for protection against radiation in effect prior to January 1...

10 CFR 20.2106 - Records of individual monitoring results.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Records of individual monitoring results. 20.2106 Section 20.2106 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20... includes records required under the standards for protection against radiation in effect prior to January 1...

10 CFR 20.2106 - Records of individual monitoring results.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Records of individual monitoring results. 20.2106 Section 20.2106 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20... includes records required under the standards for protection against radiation in effect prior to January 1...

10 CFR 20.2106 - Records of individual monitoring results.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Records of individual monitoring results. 20.2106 Section 20.2106 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20... includes records required under the standards for protection against radiation in effect prior to January 1...

10 CFR 20.2106 - Records of individual monitoring results.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Records of individual monitoring results. 20.2106 Section 20.2106 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20... includes records required under the standards for protection against radiation in effect prior to January 1...

Informed Decision Making for In-Home Use of Motion Sensor-Based Monitoring Technologies

ERIC Educational Resources Information Center

Bruce, Courtenay R.

2012-01-01

Motion sensor-based monitoring technologies are designed to maintain independence and safety of older individuals living alone. These technologies use motion sensors that are placed throughout older individuals' homes in order to derive information about eating, sleeping, and leaving/returning home habits. Deviations from normal behavioral…

Using a Sequence of Earcons to Monitor Multiple Simulated Patients.

PubMed

Hickling, Anna; Brecknell, Birgit; Loeb, Robert G; Sanderson, Penelope

2017-03-01

The aim of this study was to determine whether a sequence of earcons can effectively convey the status of multiple processes, such as the status of multiple patients in a clinical setting. Clinicians often monitor multiple patients. An auditory display that intermittently conveys the status of multiple patients may help. Nonclinician participants listened to sequences of 500-ms earcons that each represented the heart rate (HR) and oxygen saturation (SpO 2 ) levels of a different simulated patient. In each sequence, one, two, or three patients had an abnormal level of HR and/or SpO 2 . In Experiment 1, participants reported which of nine patients in a sequence were abnormal. In Experiment 2, participants identified the vital signs of one, two, or three abnormal patients in sequences of one, five, or nine patients, where the interstimulus interval (ISI) between earcons was 150 ms. Experiment 3 used the five-sequence condition of Experiment 2, but the ISI was either 150 ms or 800 ms. Participants reported which patient(s) were abnormal with median 95% accuracy. Identification accuracy for vital signs decreased as the number of abnormal patients increased from one to three, p < .001, but accuracy was unaffected by number of patients in a sequence. Overall, identification accuracy was significantly higher with an ISI of 800 ms (89%) compared with an ISI of 150 ms (83%), p < .001. A multiple-patient display can be created by cycling through earcons that represent individual patients. The principles underlying the multiple-patient display can be extended to other vital signs, designs, and domains.

Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods

PubMed Central

Asadov, Chingiz; Aliyeva, Gunay; Mustafayeva, Kamala

2017-01-01

Background: Thiopurine S-methyltransferase (TPMT) enzyme metabolizes thiopurine drugs which are widely used in various disciplines as well as in leukemias. Individual enzyme activity varies depending on the genetic polymorphisms of TPMT gene located at chromosome 6. Up to 14% of popu-lation is known to have a decreased enzyme activity, and if treated with standard doses of thiopurines, these individuals are at a high risk of severe Adverse Drug Reactions (ADR) as myelosuppression, gas-trointestinal intolerance, pancreatitis and hypersensitivity. However, TPMT-deficient patients can suc-cessfully be treated with decreased thiopurine doses if enzyme status is identified by a prior testing. TPMT status identification is a pioneering experience in application of pharmacogenetic testing in clini-cal settings. 4 TPMT (*2, *3A, *3B, *3C) alleles are known to account for 80-95% of a decreased en-zyme activity, and therefore, identifying the presence of these alleles supported by phenotypic measure-ment of the enzyme activity can reveal patient’s TPMT status. Evaluation of the levels of thiopurine me-tabolites further supports the practice of appropriate dose adjustment by providing the efficient monitor-ing of drug cytotoxicity. Conclusion: We hereby review the thiopurine pharmacogenetics and the methods applied in common practice to evaluate patient’s TPMT status. PMID:28552060

Risk Prevention of Spreading Emerging Infectious Diseases Using a HybridCrowdsensing Paradigm, Optical Sensors, and Smartphone.

PubMed

Edoh, Thierry

2018-04-10

The risk of spreading diseases within (ad-hoc)crowds and the need to pervasively screen asymptomatic individuals to protect the population against emerging infectious diseases, request permanentcrowd surveillance., particularly in high-risk regions. Thecase of Ebola epidemic in West Africa in recent years has shown the need for pervasive screening. The trend today in diseases surveillance is consisting of epidemiological data collection about emerging infectious diseases using social media, wearable sensors systems, or mobile applications and data analysis. This approach presents various limitations. This paper proposes a novel approach for diseases monitoring and risk prevention of spreading infectious diseases. The proposed approach, aiming at overcoming the limitation of existing disease surveillance approaches, combines the hybrid crowdsensing paradigm with sensing individuals' bio-signals using optical sensors for monitoring any risks of spreading emerging infectious diseases in any (ad-hoc) crowds. A proof-of-concept has been performed using a drone armed with a cat s60 smartphone featuring a Forward Looking Infra-Red (FLIR) camera. According to the results of the conducted experiment, the concept has the potential to improve the conventional epidemiological data collection. The measurement is reliable, and the recorded data are valid. The measurement error rates are about 8%.

Vibration-based monitoring for performance evaluation of flexible civil structures in Japan

PubMed Central

FUJINO, Yozo

2018-01-01

The vibration-based monitoring of flexible civil structures and performance evaluation from this monitoring are reviewed, with an emphasis on research and practice in Japan and the author’s experiences. Some new findings and unexpected vibrations from the monitoring of real bridges and buildings are reported to emphasize the importance of monitoring. Future developments and applications of vibration-based monitoring to civil infrastructure management are also described. Many examples are taken from the author’s past 30 years’ experience of research on bridge dynamics. PMID:29434082

Titration of Alanine Monitored by NMR Spectroscopy: A Biochemistry Laboratory Experiment

ERIC Educational Resources Information Center

Waller, Francis J.; And Others

1977-01-01

The experiment described here involves simultaneous monitoring of pH and NMR chemical shifts during an aqueous titration of alpha- and beta-alanine. This experiment is designed for use in an undergraduate biochemistry course. (MR)

Contemporary NMR Studies of Protein Electrostatics.

PubMed

Hass, Mathias A S; Mulder, Frans A A

2015-01-01

Electrostatics play an important role in many aspects of protein chemistry. However, the accurate determination of side chain proton affinity in proteins by experiment and theory remains challenging. In recent years the field of nuclear magnetic resonance spectroscopy has advanced the way that protonation states are measured, allowing researchers to examine electrostatic interactions at an unprecedented level of detail and accuracy. Experiments are now in place that follow pH-dependent (13)C and (15)N chemical shifts as spatially close as possible to the sites of protonation, allowing all titratable amino acid side chains to be probed sequence specifically. The strong and telling response of carefully selected reporter nuclei allows individual titration events to be monitored. At the same time, improved frameworks allow researchers to model multiple coupled protonation equilibria and to identify the underlying pH-dependent contributions to the chemical shifts.

Investigating the Association of Eye Gaze Pattern and Diagnostic Error in Mammography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voisin, Sophie; Pinto, Frank M; Xu, Songhua

2013-01-01

The objective of this study was to investigate the association between eye-gaze patterns and the diagnostic accuracy of radiologists for the task of assessing the likelihood of malignancy of mammographic masses. Six radiologists (2 expert breast imagers and 4 Radiology residents of variable training) assessed the likelihood of malignancy of 40 biopsy-proven mammographic masses (20 malignant and 20 benign) on a computer monitor. Eye-gaze data were collected using a commercial remote eye-tracker. Upon reviewing each mass, the radiologists were also asked to provide their assessment regarding the probability of malignancy of the depicted mass as well as a rating regardingmore » the perceived difficulty of the diagnostic task. The collected data were analyzed using established algorithms and various quantitative metrics were extracted to characterize the recorded gaze patterns. The extracted metrics were correlated with the radiologists diagnostic decisions and perceived complexity scores. Results showed that the visual gaze pattern of radiologists varies substantially, not only depending on their experience level but also among individuals. However, some eye gaze metrics appear to correlate with diagnostic error and perceived complexity more consistently. These results suggest that although gaze patterns are generally associated with diagnostic error and the human perceived difficulty of the diagnostic task, there are substantially individual differences that are not explained simply by the experience level of the individual performing the diagnostic task.« less

Self-efficacy: a useful construct to promote physical activity in people with stable chronic heart failure.

PubMed

Du, HuiYun; Everett, Bronwyn; Newton, Phillip J; Salamonson, Yenna; Davidson, Patricia M

2012-02-01

To explore the conceptual underpinnings of self-efficacy to address the barriers to participating in physical activity and propose a model of intervention. The benefits of physical activity in reducing cardiovascular risk have led to evidence-based recommendations for patients with heart disease, including those with chronic heart failure. However, adherence to best practice recommendations is often suboptimal, particularly in those individuals who experience high symptom burden and feel less confident to undertake physical activity. Self-efficacy is the degree of confidence an individual has in his/her ability to perform behaviour under several specific circumstances. Four factors influence an individual's level of self-efficacy: (1) past performance, (2) vicarious experience, (3) verbal persuasion and (4) physiological arousal. Discursive. Using the method of a discursive paper, this article seeks to explore the conceptual underpinnings of self-efficacy to address the barriers to participating in physical activity and proposes a model of intervention, the Home-Heart-Walk, to promote physical activity and monitor functional status. Implementing effective interventions to promote physical activities require appreciation of factors impacting on behaviour change. Addressing concepts relating to self-efficacy in physical activity interventions may promote participation and adherence in the longer term. The increasing burden of chronic disease and the emphasis on self-management strategies underscore the importance of promoting adherence to recommendations, such as physical activity. © 2011 Blackwell Publishing Ltd.

10 CFR 835.703 - Other monitoring records.

Code of Federal Regulations, 2010 CFR

2010-01-01

....1102(d); (b) Results of monitoring used to determine individual occupational dose from external and internal sources; (c) Results of monitoring for the release and control of material and equipment as...

Reporting Multiple Individual Injuries in Studies of Team Ball Sports: A Systematic Review of Current Practice.

PubMed

Fortington, Lauren V; van der Worp, Henk; van den Akker-Scheek, Inge; Finch, Caroline F

2017-06-01

To identify and prioritise targets for injury prevention efforts, injury incidence studies are widely reported. The accuracy and consistency in calculation and reporting of injury incidence is crucial. Many individuals experience more than one injury but multiple injuries are not consistently reported in sport injury incidence studies. The aim of this systematic review was to evaluate current practice of how multiple injuries within individuals have been defined and reported in prospective, long-term, injury studies in team ball sports. A systematic search of three online databases for articles published before 2016. Publications were included if (1) they collected prospective data on musculoskeletal injuries in individual participants; (2) the study duration was >1 consecutive calendar year/season; and (3) individuals were the unit of analysis. Key study features were summarised, including definitions of injury, how multiple individual injuries were reported and results relating to multiple injuries. Of the 71 publications included, half did not specifically indicate multiple individual injuries; those that did were largely limited to reporting recurrent injuries. Eight studies reported the number/proportion of athletes with more than one injury, and 11 studies presented the mean/number of injuries per athlete. Despite it being relatively common to collect data on individuals across more than one season, the reporting of multiple injuries within individuals is much more limited. Ultimately, better addressing of multiple injuries will improve the accuracy of injury incidence studies and enable more precise targeting and monitoring of the effectiveness of preventive interventions.

Monitoring of nanoclay-protein adsorption isotherms via fluorescence techniques.

PubMed

Felbeck, Tom; Moss, Sebastian; Botas, Alexandre M P; Lezhnina, Marina M; Ferreira, Rute A S; Carlos, Luís D; Kynast, Ulrich H

2017-09-01

The investigation of nanoparticles and their interaction with bio-macromolecules have become an important issue; the widely discussed protein corona around nanoparticles and their biological fate in general have drawn particular attention. Here, we focus on nanoclay dispersions and the use of solvatochromic fluorescent dyes (Dansyl and Coumarin 153) for monitoring the interaction with two model proteins, bovine serum albumin and β-lactoglobulin. On one hand, these dyes are poorly emissive in water, but experience a boost in their fluorescence when adsorbed into the hydrophobic domains of proteins. On the other hand, (nano)clays and clay minerals have previously been investigated in terms of their individual protein adsorption isotherms and their usefulness for the solubilization of water-insoluble dyes into an aqueous environment. In the following, we have combined all three individual parts (nanoclay, fluorophore and protein) in dispersions in a wide range of concentration ratios to systematically study the various adsorption processes via fluorescence techniques. In order to clarify the extent of dye diffusion and adsorption-desorption equilibria in the investigations, nanoclay hybrids with an adsorbed dye (Coumarin 153) and a covalently conjugated dye (Dansyl) were compared. The results suggest that the fluorescence progression of protein titration curves correlate with the amount of protein adsorbed, matching their reported adsorption isotherms on hectorite clays. Furthermore, experimental data on the protein monolayer formation around the nanoclays could be extracted due to only minor alterations of the dispersions' optical quality and transparency. In this manner, a fluorescence-based monitor for the formation of the globular protein layer around the nanoclay was realized. Copyright © 2017 Elsevier B.V. All rights reserved.

Suggestions for planning a migration-monitoring network based on the experience of establishing and operating the maps program

Treesearch

David F. DeSante

2005-01-01

Based on the experience of creating and implementing the Monitoring Avian Productivity and Survivorship (MAPS) program, I suggest that, to be successful, a migration-monitoring network must: (1) provide strong justification for the data it proposes to collect; (2) provide direct links between those monitoring data and both research and management goals; (3) provide...

Prediction of Mortality Based on Facial Characteristics

PubMed Central

Delorme, Arnaud; Pierce, Alan; Michel, Leena; Radin, Dean

2016-01-01

Recent studies have shown that characteristics of the face contain a wealth of information about health, age and chronic clinical conditions. Such studies involve objective measurement of facial features correlated with historical health information. But some individuals also claim to be adept at gauging mortality based on a glance at a person’s photograph. To test this claim, we invited 12 such individuals to see if they could determine if a person was alive or dead based solely on a brief examination of facial photographs. All photos used in the experiment were transformed into a uniform gray scale and then counterbalanced across eight categories: gender, age, gaze direction, glasses, head position, smile, hair color, and image resolution. Participants examined 404 photographs displayed on a computer monitor, one photo at a time, each shown for a maximum of 8 s. Half of the individuals in the photos were deceased, and half were alive at the time the experiment was conducted. Participants were asked to press a button if they thought the person in a photo was living or deceased. Overall mean accuracy on this task was 53.8%, where 50% was expected by chance (p < 0.004, two-tail). Statistically significant accuracy was independently obtained in 5 of the 12 participants. We also collected 32-channel electrophysiological recordings and observed a robust difference between images of deceased individuals correctly vs. incorrectly classified in the early event related potential (ERP) at 100 ms post-stimulus onset. Our results support claims of individuals who report that some as-yet unknown features of the face predict mortality. The results are also compatible with claims about clairvoyance warrants further investigation. PMID:27242466

The baric probe: a novel long-term implantable intracranial pressure monitor with ultrasound-based interrogation.

PubMed

Limbrick, David D; Lake, Stephen; Talcott, Michael; Alexander, Benjamin; Wight, Samuel; Willie, Jon T; Richard, William D; Genin, Guy M; Leuthardt, Eric C

2012-12-01

Prompt diagnosis of shunt malfunction is critical in preventing neurological morbidity and death in individuals with hydrocephalus; however, diagnostic methods for this condition remain limited. For several decades, investigators have sought a long-term, implantable intracranial pressure (ICP) monitor to assist in the diagnosis of shunt malfunction, but efforts have been impeded by device complexity, marked measurement drift, and limited instrumentation lifespan. In the current report, the authors introduce an entirely novel, simple, compressible gas design that addresses each of these problems. The device described herein, termed the "baric probe," consists of a subdural fluid bladder and multichannel indicator that monitors the position of an air-fluid interface (AFI). A handheld ultrasound probe is used to interrogate the baric probe in vivo, permitting noninvasive ICP determination. To assess the function of device prototypes, ex vivo experiments were conducted using a water column, and short- and long-term in vivo experiments were performed using a porcine model with concurrent measurements of ICP via a fiberoptic monitor. Following a toe region of approximately 2 cm H(2)O, the baric probe's AFI demonstrated a predictable linear relationship to ICP in both ex vivo and in vivo models. After a 2-week implantation of the device, this linear relationship remained robust and reproducible. Further, changes in ICP were observed with the baric probe, on average, 3 seconds in advance of the fiberoptic ICP monitor reading. The authors demonstrate "proof-of-concept" and feasibility for the baric probe, a long-term implantable ICP monitor designed to facilitate the prompt and accurate diagnosis of shunt malfunction. The baric probe showed a consistent linear relationship between ICP and the device's AFI in ex vivo and short- and long-term in vivo models. With a low per-unit cost, a reduced need for radiography or CT, and an indicator that can be read with a handheld ultrasound probe that interfaces with any smart phone, the baric probe promises to simplify the care of patients with shunt-treated hydrocephalus throughout both the developed and the developing world.

A wireless centrifuge force microscope (CFM) enables multiplexed single-molecule experiments in a commercial centrifuge.

PubMed

Hoang, Tony; Patel, Dhruv S; Halvorsen, Ken

2016-08-01

The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. We validated the instrument by performing single-molecule force shearing of short DNA duplexes. For a 7 bp duplex, we observed over 1000 dissociation events due to force dependent shearing from 2 pN to 12 pN with dissociation times in the range of 10-100 s. We extended the measurement to a 10 bp duplex, applying a 12 pN force clamp and directly observing single-molecule dissociation over an 85 min experiment. Our new CFM module facilitates simple and inexpensive experiments that dramatically improve access to single-molecule analysis.

Doing accelerator physics using SDDS, UNIX, and EPICS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borland, M.; Emery, L.; Sereno, N.

1995-12-31

The use of the SDDS (Self-Describing Data Sets) file protocol, together with the UNIX operating system and EPICS (Experimental Physics and Industrial Controls System), has proved powerful during the commissioning of the APS (Advanced Photon Source) accelerator complex. The SDDS file protocol has permitted a tool-oriented approach to developing applications, wherein generic programs axe written that function as part of multiple applications. While EPICS-specific tools were written for data collection, automated experiment execution, closed-loop control, and so forth, data processing and display axe done with the SDDS Toolkit. Experiments and data reduction axe implemented as UNIX shell scripts that coordinatemore » the execution of EPICS specific tools and SDDS tools. Because of the power and generic nature of the individual tools and of the UNIX shell environment, automated experiments can be prepared and executed rapidly in response to unanticipated needs or new ideas. Examples are given of application of this methodology to beam motion characterization, beam-position-monitor offset measurements, and klystron characterization.« less

The VISPA internet platform for outreach, education and scientific research in various experiments

NASA Astrophysics Data System (ADS)

van Asseldonk, D.; Erdmann, M.; Fischer, B.; Fischer, R.; Glaser, C.; Heidemann, F.; Müller, G.; Quast, T.; Rieger, M.; Urban, M.; Welling, C.

2015-12-01

VISPA provides a graphical front-end to computing infrastructures giving its users all functionality needed for working conditions comparable to a personal computer. It is a framework that can be extended with custom applications to support individual needs, e.g. graphical interfaces for experiment-specific software. By design, VISPA serves as a multipurpose platform for many disciplines and experiments as demonstrated in the following different use-cases. A GUI to the analysis framework OFFLINE of the Pierre Auger collaboration, submission and monitoring of computing jobs, university teaching of hundreds of students, and outreach activity, especially in CERN's open data initiative. Serving heterogeneous user groups and applications gave us lots of experience. This helps us in maturing the system, i.e. improving the robustness and responsiveness, and the interplay of the components. Among the lessons learned are the choice of a file system, the implementation of websockets, efficient load balancing, and the fine-tuning of existing technologies like the RPC over SSH. We present in detail the improved server setup and report on the performance, the user acceptance and the realized applications of the system.

Monitoring arrangement for vented nuclear fuel elements

DOEpatents

Campana, Robert J.

1981-01-01

In a nuclear fuel reactor core, fuel elements are arranged in a closely packed hexagonal configuration, each fuel element having diametrically opposed vents permitting 180.degree. rotation of the fuel elements to counteract bowing. A grid plate engages the fuel elements and forms passages for communicating sets of three, four or six individual vents with respective monitor lines in order to communicate vented radioactive gases from the fuel elements to suitable monitor means in a manner readily permitting detection of leakage in individual fuel elements.

A Framework for Monitoring Progress Using Summary Measures of Health.

PubMed

Madans, Jennifer H; Weeks, Julie D

2016-10-01

Initiatives designed to monitor health typically incorporate numerous specific measures of health and the health system to assess improvements, or lack thereof, for policy and program purposes. The addition of summary measures provides overarching information which is essential for determining whether the goals of such initiatives are met. Summary measures are identified that relate to the individual indicators but that also reflect movement in the various parts of the system. A hierarchical framework that is conceptually consistent and which utilizes a succinct number of summary measures incorporating indicators of functioning and participation is proposed. While a large set of individual indicators can be useful for monitoring progress, these individual indicators do not provide an overall evaluation of health, defined broadly, at the population level. A hierarchical framework consisting of summary measures is important for monitoring the success of health improvement initiatives. © The Author(s) 2016.

Individual Differences in Working Memory Capacity Predict Action Monitoring and the Error-Related Negativity

ERIC Educational Resources Information Center

Miller, A. Eve; Watson, Jason M.; Strayer, David L.

2012-01-01

Neuroscience suggests that the anterior cingulate cortex (ACC) is responsible for conflict monitoring and the detection of errors in cognitive tasks, thereby contributing to the implementation of attentional control. Though individual differences in frontally mediated goal maintenance have clearly been shown to influence outward behavior in…

Tailoring Messages to Individual Differences in Monitoring-Blunting Styles to Increase Fruit and Vegetable Intake

ERIC Educational Resources Information Center

Williams-Piehota, Pamela; Latimer, Amy E.; Katulak, Nicole A.; Cox, Ashley; Silvera, Stephanie A. N.; Mowad, Linda; Salovey, Peter

2009-01-01

Objective: To examine whether messages matched to individuals' monitoring-blunting coping styles (MBCS) are more effective in increasing fruit and vegetable intake than mismatched messages. MBCS refers to the tendency to either attend to and amplify, or distract oneself from and minimize threatening information. Design/Setting: Randomly assigned…

Community Air Monitoring Training

EPA Pesticide Factsheets

EPA hosted a training workshop to share tools used to conduct citizen science projects involving Next Generation Air Monitoring (NGAM) technology and to educate interested groups and individuals on best practices for successful air monitoring projects.

Role of Self-help Group in Substance Addiction Recovery

NASA Astrophysics Data System (ADS)

Das, Prangya Paramita Priyadarshini

2012-11-01

Background: The Narcotics Anonymous (NA)/Alcoholic Anonymous(AA) is based on the philosophy of self-help, where the former addicts and recovering addicts share experiences, provide emotional support and do active monitoring through mentoring. In mentoring, a former addict with longer duration of drug-free life acts as a guide to the newly recovering addict. Objective: The objective was to study the effect of involvement in self help group upon addictís level of depression, functional social support, and anxiety. Method: The size of the sample was 60. 30 addicts were taken from rehabilitation centre and 30 were taken from self-help groups. ANOVA was used to analyze the result. Result: In all the criteria it was found that there exists a significant impact of Self-help group. Conclusion: Self-help group provide clients with a social network of individuals with similar problems and experiences, since most of these individuals may be isolated from society due to the social stigma attached to their addictions. The transition from being help recipients to being helpers enables recovering addicts to build their self-confidence and feelings of being wanted and desired in society, which facilitates their self-confidence and positive self-esteem.

Reducing Risk in CO2 Sequestration: A Framework for Integrated Monitoring of Basin Scale Injection

NASA Astrophysics Data System (ADS)

Seto, C. J.; Haidari, A. S.; McRae, G. J.

2009-12-01

Geological sequestration of CO2 is an option for stabilization of atmospheric CO2 concentrations. Technical ability to safely store CO2 in the subsurface has been demonstrated through pilot projects and a long history of enhanced oil recovery and acid gas disposal operations. To address climate change, current injection operations must be scaled up by a factor of 100, raising issues of safety and security. Monitoring and verification is an essential component in ensuring safe operations and managing risk. Monitoring provides assurance that CO2 is securely stored in the subsurface, and the mechanisms governing transport and storage are well understood. It also provides an early warning mechanism for identification of anomalies in performance, and a means for intervention and remediation through the ability to locate the CO2. Through theoretical studies, bench scale experiments and pilot tests, a number of technologies have demonstrated their ability to monitor CO2 in the surface and subsurface. Because the focus of these studies has been to demonstrate feasibility, individual techniques have not been integrated to provide a more robust method for monitoring. Considering the large volumes required for injection, size of the potential footprint, length of time a project must be monitored and uncertainty, operational considerations of cost and risk must balance safety and security. Integration of multiple monitoring techniques will reduce uncertainty in monitoring injected CO2, thereby reducing risk. We present a framework for risk management of large scale injection through model based monitoring network design. This framework is applied to monitoring CO2 in a synthetic reservoir where there is uncertainty in the underlying permeability field controlling fluid migration. Deformation and seismic data are used to track plume migration. A modified Ensemble Kalman filter approach is used to estimate flow properties by jointly assimilating flow and geomechanical observations. Issues of risk, cost and uncertainty are considered.

Error-Monitoring in Response to Social Stimuli in Individuals with Higher-Functioning Autism Spectrum Disorder

PubMed Central

McMahon, Camilla M.; Henderson, Heather A.

2014-01-01

Error-monitoring, or the ability to recognize one's mistakes and implement behavioral changes to prevent further mistakes, may be impaired in individuals with Autism Spectrum Disorder (ASD). Children and adolescents (ages 9-19) with ASD (n = 42) and typical development (n = 42) completed two face processing tasks that required discrimination of either the gender or affect of standardized face stimuli. Post-error slowing and the difference in Error-Related Negativity amplitude between correct and incorrect responses (ERNdiff) were used to index error-monitoring ability. Overall, ERNdiff increased with age. On the Gender Task, individuals with ASD had a smaller ERNdiff than individuals with typical development; however, on the Affect Task, there were no significant diagnostic group differences on ERNdiff. Individuals with ASD may have ERN amplitudes similar to those observed in individuals with typical development in more social contexts compared to less social contexts due to greater consequences for errors, more effortful processing, and/or reduced processing efficiency in these contexts. Across all participants, more post-error slowing on the Affect Task was associated with better social cognitive skills. PMID:25066088

Cooperative vaccinia infection demonstrated at the single-cell level using FluidFM.

PubMed

Stiefel, Philipp; Schmidt, Florian I; Dörig, Pablo; Behr, Pascal; Zambelli, Tomaso; Vorholt, Julia A; Mercer, Jason

2012-08-08

The mechanisms used by viruses to enter and replicate within host cells are subjects of intense investigation. These studies are ultimately aimed at development of new drugs that interfere with these processes. Virus entry and infection are generally monitored by dispensing bulk virus suspensions on layers of cells without accounting for the fate of each virion. Here, we take advantage of the recently developed FluidFM to deposit single vaccinia virions onto individual cells in a controlled manner. While the majority of virions were blocked prior to early gene expression, infection of individual cells increased in a nondeterministic fashion with respect to the number of viruses placed. Microscopic analyses of several stages of the virus lifecycle indicated that this was the result of cooperativity between virions during early stages of infection. These findings highlight the importance of performing controlled virus infection experiments at the single cell level.

The "Speedy" Synthesis of Atom-Specific (15)N Imino/Amido-Labeled RNA.

PubMed

Neuner, Sandro; Santner, Tobias; Kreutz, Christoph; Micura, Ronald

2015-08-10

Although numerous reports on the synthesis of atom-specific (15)N-labeled nucleosides exist, fast and facile access to the corresponding phosphoramidites for RNA solid-phase synthesis is still lacking. This situation represents a severe bottleneck for NMR spectroscopic investigations on functional RNAs. Here, we present optimized procedures to speed up the synthesis of (15)N(1) adenosine and (15)N(1) guanosine amidites, which are the much needed counterparts of the more straightforward-to-achieve (15)N(3) uridine and (15)N(3) cytidine amidites in order to tap full potential of (1)H/(15)N/(15)N-COSY experiments for directly monitoring individual Watson-Crick base pairs in RNA. Demonstrated for two preQ1 riboswitch systems, we exemplify a versatile concept for individual base-pair labeling in the analysis of conformationally flexible RNAs when competing structures and conformational dynamics are encountered. © 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.

The “Speedy” Synthesis of Atom-Specific 15N Imino/Amido-Labeled RNA

PubMed Central

Kreutz, Christoph; Micura, Ronald

2016-01-01

Although numerous reports on the synthesis of atom-specific 15N-labeled nucleosides exist, fast and facile access to the corresponding phosphoramidites for RNA solid-phase synthesis is still lacking. This situation represents a severe bottleneck for NMR spectroscopic investigations on functional RNAs. Here, we present optimized procedures to speed up the synthesis of 15N(1) adenosine and 15N(1) guanosine amidites, which are the much needed counterparts of the more straightforward-to-achieve 15N(3) uridine and 15N(3) cytidine amidites in order to tap full potential of 1H/15N/15N-COSY experiments for directly monitoring individual Watson–Crick base pairs in RNA. Demonstrated for two preQ1 riboswitch systems, we exemplify a versatile concept for individual base-pair labeling in the analysis of conformationally flexible RNAs when competing structures and conformational dynamics are encountered. PMID:26237536

Perceived Parental Monitoring and Sexual Orientation Moderate Lifetime Acts of Non-Suicidal Self-Injury.

PubMed

Benau, Erik M; Jenkins, Abigail L; Conner, Bradley T

2017-01-01

Being non-heterosexual, particularly bisexual, is associated with high rates of engagement in NSSI amongst young adults. The goal of the present study was to determine if parenting practices, specifically parental monitoring, and sexual orientation moderate engagement with NSSI. Undergraduates (N = 1,353) completed a survey on sexual orientation, non-suicidal self-injury (NSSI) acts, and multiple aspects of perceived parental monitoring during high school. Moderation analyses revealed that most facets of parental monitoring were similarly negatively correlated with NSSI for both individuals whose sexual orientation where nearly, or entirely, gay and heterosexual youth. Youth who were neither exclusively heterosexual nor exclusively gay (mixed sexual orientation) reported the most NSSI acts, and no facet of parental monitoring predicted reduced NSSI acts for this group. While previous literature shows that many aspects of parental monitoring may be protective against engagement in health risk behaviors, the present study adds to these findings that similar aspects are negatively associated with self-injurious behavior for some, but not all, individuals. More research is needed to better understand the causes of increased NSSI for individuals with a mixed sexual orientation.

An experimental test for age-related improvements in reproductive performance in a frog that cares for its young

NASA Astrophysics Data System (ADS)

Dugas, Matthew B.; Moore, Michael P.; Wamelink, Caitlin N.; Richards-Zawacki, Corinne L.; Martin, Ryan A.

2015-10-01

Reproductive performance often increases with age in long-lived iteroparous organisms, a pattern that can result from within-individual increases in effort and/or competence. In free-living populations, it is typically difficult to distinguish these mechanisms or to isolate particular features of reproduction-influencing outcomes. In captive Oophaga pumilio, a frog in which mothers provide extended offspring provisioning via trophic eggs, we experimentally manipulated the age at which females started breeding and then monitored them across repeated reproductive events. This experiment allowed us to decouple age and experience and isolate maternal care as the proximate source of any differences in performance. Younger first-time mothers produced larger broods than older first-time mothers, but did not rear more offspring to independence. Across repeated reproductive events, maternal age was unassociated with any metric of performance. At later reproductive events, however, mothers produced fewer metamorphs, and a lower proportion of individuals in their broods reached independence. These patterns suggest that performance does not improve with age or breeding experience in this frog, and that eventual declines in performance are driven by reproductive activity, not age per se. Broadly, age-specific patterns of reproductive performance may depend on the proximate mechanism by which parents influence offspring fitness and how sensitive these are to effort and competence.

Experiences with SCRAMx alcohol monitoring technology in 100 alcohol treatment outpatients.

PubMed

Alessi, Sheila M; Barnett, Nancy P; Petry, Nancy M

2017-09-01

Transdermal alcohol monitoring technology allows for new research on alcohol use disorders. This study assessed feasibility, acceptability, and adherence with this technology in the context of two clinical research trials. Participants were the first 100 community-based alcohol treatment outpatients enrolled in randomized studies that monitored drinking with the secure continuous remote alcohol monitor (SCRAMx ® ) for 12 weeks. Study 1 participants were randomized to usual care (n=36) or usual care with contingency management incentives for treatment attendance (CM-Att; n=30). Study 2 participants were randomized to usual care (n=17) or usual care with CM for each day of no drinking per SCRAMx (CM-Abst; n=17). After 12 weeks, participants completed a survey about the bracelet. Nine percent of individuals screened (54 of 595) declined participation because of the bracelet. Of participants, 84% provided 12weeks of data, and 96% of bracelets were returned fully intact. Ninety-four equipment tampers occurred, affecting 2% of monitoring days; 56% (67) of tampers coincided with detected drinking. Common concerns reported by participants were skin marks (58%), irritation (54%), and interfered with clothing choices (51%), but severity ratings were generally mild (60%-94%). Eighty-one percent of participants reported that the bracelet helped them reduce drinking, and 75% indicated that they would wear it for longer. A common suggestion for improvement was to reduce the size of the bracelet. Results support the viability of transdermal monitoring in voluntary substance abuse treatment participants for an extended duration. Issues to consider for future applications of this technology are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

Brief mindfulness meditation training reduces mind wandering: The critical role of acceptance.

PubMed

Rahl, Hayley A; Lindsay, Emily K; Pacilio, Laura E; Brown, Kirk W; Creswell, J David

2017-03-01

Mindfulness meditation programs, which train individuals to monitor their present-moment experience in an open or accepting way, have been shown to reduce mind wandering on standardized tasks in several studies. Here we test 2 competing accounts for how mindfulness training reduces mind wandering, evaluating whether the attention-monitoring component of mindfulness training alone reduces mind wandering or whether the acceptance training component is necessary for reducing mind wandering. Healthy young adults (N = 147) were randomized to either a 3-day brief mindfulness training condition incorporating instruction in both attention monitoring and acceptance, a mindfulness training condition incorporating attention monitoring instruction only, a relaxation training condition, or an active reading-control condition. Participants completed measures of dispositional mindfulness and treatment expectancies before the training session on Day 1 and then completed a 6-min Sustained Attention to Response Task (SART) measuring mind wandering after the training session on Day 3. Acceptance training was important for reducing mind wandering, such that the attention-monitoring plus acceptance mindfulness training condition had the lowest mind wandering relative to the other conditions, including significantly lower mind wandering than the attention-monitoring only mindfulness training condition. In one of the first experimental mindfulness training dismantling studies to-date, we show that training in acceptance is a critical driver of mindfulness-training reductions in mind wandering. This effect suggests that acceptance skills may facilitate emotion regulation on boring and frustrating sustained attention tasks that foster mind wandering, such as the SART. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Production of beta-gamma coincidence spectra of individual radioxenon isotopes for improved analysis of nuclear explosion monitoring data

NASA Astrophysics Data System (ADS)

Haas, Derek Anderson

Radioactive xenon gas is a fission product released in the detonation of nuclear devices that can be detected in atmospheric samples far from the detonation site. In order to improve the capabilities of radioxenon detection systems, this work produces beta-gamma coincidence spectra of individual isotopes of radioxenon. Previous methods of radioxenon production consisted of the removal of mixed isotope samples of radioxenon gas released from fission of contained fissile materials such as 235U. In order to produce individual samples of the gas, isotopically enriched stable xenon gas is irradiated with neutrons. The detection of the individual isotopes is also modeled using Monte Carlo simulations to produce spectra. The experiment shows that samples of 131mXe, 133 Xe, and 135Xe with a purity greater than 99% can be produced, and that a sample of 133mXe can be produced with a relatively low amount of 133Xe background. These spectra are compared to models and used as essential library data for the Spectral Deconvolution Analysis Tool (SDAT) to analyze atmospheric samples of radioxenon for evidence of nuclear events.

Self-identified Obese People Request Less Money: A Field Experiment

PubMed Central

Proestakis, Antonios; Brañas-Garza, Pablo

2016-01-01

Empirical evidence suggests that obese people are discriminated in different social environments, such as the work place. Yet, the degree to which obese people are internalizing and adjusting their own behavior as a result of this discriminatory behavior has not been thoroughly studied. We develop a proxy for measuring experimentally the “self-weight bias” by giving to both self-identified obese (n = 90) and non-obese (n = 180) individuals the opportunity to request a positive amount of money after having performed an identical task. Consistent with the System Justification Theory, we find that self-identified obese individuals, due to a preexisting false consciousness, request significantly lower amounts of money than non-obese ones. A within subject comparison between self-reports and external monitors' evaluations reveals that the excessive weight felt by the “self” but not reported by evaluators captures the self-weight bias not only for obese but also for non-obese individuals. Linking our experimental results to the supply side of the labor market, we argue that self-weight bias, as expressed by lower salary requests, enhances discriminatory behavior against individuals who feel, but may not actually be, obese and consequently exacerbates the wage gap across weight. PMID:27721803

Self-identified Obese People Request Less Money: A Field Experiment.

PubMed

Proestakis, Antonios; Brañas-Garza, Pablo

2016-01-01

Empirical evidence suggests that obese people are discriminated in different social environments, such as the work place. Yet, the degree to which obese people are internalizing and adjusting their own behavior as a result of this discriminatory behavior has not been thoroughly studied. We develop a proxy for measuring experimentally the "self-weight bias" by giving to both self-identified obese ( n = 90) and non-obese ( n = 180) individuals the opportunity to request a positive amount of money after having performed an identical task. Consistent with the System Justification Theory, we find that self-identified obese individuals, due to a preexisting false consciousness , request significantly lower amounts of money than non-obese ones. A within subject comparison between self-reports and external monitors' evaluations reveals that the excessive weight felt by the "self" but not reported by evaluators captures the self-weight bias not only for obese but also for non-obese individuals. Linking our experimental results to the supply side of the labor market, we argue that self-weight bias, as expressed by lower salary requests, enhances discriminatory behavior against individuals who feel, but may not actually be, obese and consequently exacerbates the wage gap across weight.

Microfluidic Cultivation and Laser Tweezers Raman Spectroscopy of E. coli under Antibiotic Stress

PubMed Central

Pilát, Zdeněk; Bernatová, Silvie; Ježek, Jan; Kirchhoff, Johanna; Tannert, Astrid; Samek, Ota; Zemánek, Pavel

2018-01-01

Analyzing the cells in various body fluids can greatly deepen the understanding of the mechanisms governing the cellular physiology. Due to the variability of physiological and metabolic states, it is important to be able to perform such studies on individual cells. Therefore, we developed an optofluidic system in which we precisely manipulated and monitored individual cells of Escherichia coli. We tested optical micromanipulation in a microfluidic chamber chip by transferring individual bacteria into the chambers. We then subjected the cells in the chambers to antibiotic cefotaxime and we observed the changes by using time-lapse microscopy. Separately, we used laser tweezers Raman spectroscopy (LTRS) in a different micro-chamber chip to manipulate and analyze individual cefotaxime-treated E. coli cells. Additionally, we performed conventional Raman micro-spectroscopic measurements of E. coli cells in a micro-chamber. We found observable changes in the cellular morphology (cell elongation) and in Raman spectra, which were consistent with other recently published observations. The principal component analysis (PCA) of Raman data distinguished between the cefotaxime treated cells and control. We tested the capabilities of the optofluidic system and found it to be a reliable and versatile solution for this class of microbiological experiments. PMID:29783713

10 CFR 835.403 - Air monitoring.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Air monitoring. 835.403 Section 835.403 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of Individuals and Areas § 835.403 Air... been prescribed. (b) Real-time air monitoring shall be performed as necessary to detect and provide...

10 CFR 835.403 - Air monitoring.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Air monitoring. 835.403 Section 835.403 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of Individuals and Areas § 835.403 Air... been prescribed. (b) Real-time air monitoring shall be performed as necessary to detect and provide...

10 CFR 835.403 - Air monitoring.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Air monitoring. 835.403 Section 835.403 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of Individuals and Areas § 835.403 Air... been prescribed. (b) Real-time air monitoring shall be performed as necessary to detect and provide...

10 CFR 835.403 - Air monitoring.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Air monitoring. 835.403 Section 835.403 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of Individuals and Areas § 835.403 Air... been prescribed. (b) Real-time air monitoring shall be performed as necessary to detect and provide...

10 CFR 835.403 - Air monitoring.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Air monitoring. 835.403 Section 835.403 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Monitoring of Individuals and Areas § 835.403 Air... been prescribed. (b) Real-time air monitoring shall be performed as necessary to detect and provide...

Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa.

PubMed

Kishnani, Priya S; Rush, Eric T; Arundel, Paul; Bishop, Nick; Dahir, Kathryn; Fraser, William; Harmatz, Paul; Linglart, Agnès; Munns, Craig F; Nunes, Mark E; Saal, Howard M; Seefried, Lothar; Ozono, Keiichi

2017-09-01

Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic disorder caused by autosomal recessive mutations or a single dominant-negative mutation in the gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). The disease is associated with a broad range of signs, symptoms, and complications, including impaired skeletal mineralization, altered calcium and phosphate metabolism, recurrent fractures, pain, respiratory problems, impaired growth and mobility, premature tooth loss, developmental delay, and seizures. Asfotase alfa is a human, recombinant enzyme replacement therapy that is approved in many countries for the treatment of patients with HPP. To address the unmet need for guidance in the monitoring of patients receiving asfotase alfa, an international panel of physicians with experience in diagnosing and managing HPP convened in May 2016 to discuss treatment monitoring parameters. The panel discussions focused on recommendations for assessing and monitoring patients after the decision to treat with asfotase alfa had been made and did not include recommendations for whom to treat. Based on the consensus of panel members, this review provides guidance on the monitoring of patients with HPP during treatment with asfotase alfa, including recommendations for laboratory, efficacy, and safety assessments and the frequency with which these should be performed during the course of treatment. Recommended assessments are based on patient age and include regular monitoring of biochemistry, skeletal radiographs, respiratory function, growth, pain, mobility and motor function, and quality of life. Because of the systemic presentation of HPP, a coordinated, multidisciplinary, team-based, patient-focused approach is recommended in the management of patients receiving asfotase alfa. Monitoring of efficacy and safety outcomes must be tailored to the individual patient, depending on medical history, clinical manifestations, availability of resources in the clinical setting, and the clinician's professional judgment. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

The Joint Experiment for Crop Assessment and Monitoring (JECAM): Synthetic Aperture Radar (SAR) Inter-Comparison Experiment

NASA Astrophysics Data System (ADS)

Dingle Robertson, L.; Hosseini, M.; Davidson, A. M.; McNairn, H.

2017-12-01

The Joint Experiment for Crop Assessment and Monitoring (JECAM) is the research and development branch of GEOGLAM (Group on Earth Observations Global Agricultural Monitoring), a G20 initiative to improve the global monitoring of agriculture through the use of Earth Observation (EO) data and remote sensing. JECAM partners represent a diverse network of researchers collaborating towards a set of best practices and recommendations for global agricultural analysis using EO data, with well monitored test sites covering a wide range of agriculture types, cropping systems and climate regimes. Synthetic Aperture Radar (SAR) for crop inventory and condition monitoring offers many advantages particularly the ability to collect data under cloudy conditions. The JECAM SAR Inter-Comparison Experiment is a multi-year, multi-partner project that aims to compare global methods for (1) operational SAR & optical; multi-frequency SAR; and compact polarimetry methods for crop monitoring and inventory, and (2) the retrieval of Leaf Area Index (LAI) and biomass estimations using models such as the Water Cloud Model (WCM) employing single frequency SAR; multi-frequency SAR; and compact polarimetry. The results from these activities will be discussed along with an examination of the requirements of a global experiment including best-date determination for SAR data acquisition, pre-processing techniques, in situ data sharing, model development and statistical inter-comparison of the results.

Study of sleeping in a chemical protective ensemble in a warfare environment. Final report 26 Aug 81-2 Dec 82

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cacioppo, G.M.; Annis, J.F.

1982-12-01

Experiments were performed to evaluate the quality of sleep experienced by individuals wearing different chemical protective ensembles (CPE). A series of seven experiments were conducted in which two test subjects slept overnight in an environmentally controlled room while wearing either pajamas (control ensemble) or one of three different CPEs. The three CPEs tested were: the standard West German ground crew ensemble, an ensemble comprised of a combination of equipment of which the Canadian chemical protective coverall was the principal item of clothing, and the U.S. Army standard ground crew ensemble Body temperatures, sleep records, and other physiological measurements were monitoredmore » overnight and form the basis of the objective evaluation. Subjective data were collected by an experiment monitor who kept the test participants under constant observation. Additionally, the participants were required to complete a standard debriefing questionnaire form each post-experiment morning. Because of the limited scope of the experiment, statistical analysis was not appropriate. However, both the objective and subjective data reflected consistent trends and allow confidence in the assessment that current U.S. and NATO CPE combinations provide for adequate sleep quality.« less

Monitoring the Implementation of IDEA: Proceedings of the National Monitoring Conference (6th, Salt Lake City, Utah, October 2002).

ERIC Educational Resources Information Center

Tschantz, Jennifer

This document presents the proceedings of the sixth National Monitoring Conference concerned with implementation of the Individuals with Disabilities Education Act. Introductory material describes the purpose and background of the document and the federal monitoring of states, including the Continuous Improvement Monitoring Process (CIMP) and…

Influences of spoken word planning on speech recognition.

PubMed

Roelofs, Ardi; Ozdemir, Rebecca; Levelt, Willem J M

2007-09-01

In 4 chronometric experiments, influences of spoken word planning on speech recognition were examined. Participants were shown pictures while hearing a tone or a spoken word presented shortly after picture onset. When a spoken word was presented, participants indicated whether it contained a prespecified phoneme. When the tone was presented, they indicated whether the picture name contained the phoneme (Experiment 1) or they named the picture (Experiment 2). Phoneme monitoring latencies for the spoken words were shorter when the picture name contained the prespecified phoneme compared with when it did not. Priming of phoneme monitoring was also obtained when the phoneme was part of spoken nonwords (Experiment 3). However, no priming of phoneme monitoring was obtained when the pictures required no response in the experiment, regardless of monitoring latency (Experiment 4). These results provide evidence that an internal phonological pathway runs from spoken word planning to speech recognition and that active phonological encoding is a precondition for engaging the pathway. 2007 APA

Monitoring individual tree-based change with airborne lidar.

PubMed

Duncanson, Laura; Dubayah, Ralph

2018-05-01

Understanding the carbon flux of forests is critical for constraining the global carbon cycle and managing forests to mitigate climate change. Monitoring forest growth and mortality rates is critical to this effort, but has been limited in the past, with estimates relying primarily on field surveys. Advances in remote sensing enable the potential to monitor tree growth and mortality across landscapes. This work presents an approach to measure tree growth and loss using multidate lidar campaigns in a high-biomass forest in California, USA. Individual tree crowns were delineated in 2008 and again in 2013 using a 3D crown segmentation algorithm, with derived heights and crown radii extracted and used to estimate individual tree aboveground biomass. Tree growth, loss, and aboveground biomass were analyzed with respect to tree height and crown radius. Both tree growth and loss rates decrease with increasing tree height, following the expectation that trees slow in growth rate as they age. Additionally, our aboveground biomass analysis suggests that, while the system is a net source of aboveground carbon, these carbon dynamics are governed by size class with the largest sources coming from the loss of a relatively small number of large individuals. This study demonstrates that monitoring individual tree-based growth and loss can be conducted with multidate airborne lidar, but these methods remain relatively immature. Disparities between lidar acquisitions were particularly difficult to overcome and decreased the sample of trees analyzed for growth rate in this study to 21% of the full number of delineated crowns. However, this study illuminates the potential of airborne remote sensing for ecologically meaningful forest monitoring at an individual tree level. As methods continue to improve, airborne multidate lidar will enable a richer understanding of the drivers of tree growth, loss, and aboveground carbon flux.

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2018 POSITION STATEMENT ON INTEGRATION OF INSULIN PUMPS AND CONTINUOUS GLUCOSE MONITORING IN PATIENTS WITH DIABETES MELLITUS.

PubMed

Grunberger, George; Handelsman, Yehuda; Bloomgarden, Zachary T; Fonseca, Vivian A; Garber, Alan J; Haas, Richard A; Roberts, Victor L; Umpierrez, Guillermo E

2018-03-01

This document represents the official position of the American Association of Clinical Endocrinologists and American College of Endocrinology. Where there are no randomized controlled trials or specific U.S. FDA labeling for issues in clinical practice, the participating clinical experts utilized their judgment and experience. Every effort was made to achieve consensus among the committee members. Position statements are meant to provide guidance, but they are not to be considered prescriptive for any individual patient and cannot replace the judgment of a clinician. AACE/ACE Task Force on Integration of Insulin Pumps and Continuous Glucose Monitoring in the Management of Patients With Diabetes Mellitus Chair George Grunberger, MD, FACP, FACE Task Force Members Yehuda Handelsman, MD, FACP, FNLA, MACE Zachary T. Bloomgarden, MD, MACE Vivian A. Fonseca, MD, FACE Alan J. Garber, MD, PhD, FACE Richard A. Haas, MD, FACE Victor L. Roberts, MD, MBA, FACP, FACE Guillermo E. Umpierrez, MD, CDE, FACP, FACE Abbreviations: AACE = American Association of Clinical Endocrinologists ACE = American College of Endocrinology A1C = glycated hemoglobin BGM = blood glucose monitoring CGM = continuous glucose monitoring CSII = continuous subcutaneous insulin infusion DM = diabetes mellitus FDA = Food & Drug Administration MDI = multiple daily injections T1DM = type 1 diabetes mellitus T2DM = type 2 diabetes mellitus SAP = sensor-augmented pump SMBG = self-monitoring of blood glucose STAR 3 = Sensor-Augmented Pump Therapy for A1C Reduction phase 3 trial.

The Influence of Wireless Self-Monitoring Program on the Relationship Between Patient Activation and Health Behaviors, Medication Adherence, and Blood Pressure Levels in Hypertensive Patients: A Substudy of a Randomized Controlled Trial.

PubMed

Kim, Ju Young; Wineinger, Nathan E; Steinhubl, Steven R

2016-06-22

Active engagement in the management of hypertension is important in improving self-management behaviors and clinical outcomes. Mobile phone technology using wireless monitoring tools are now widely available to help individuals monitor their blood pressure, but little is known about the conditions under which such technology can effect positive behavior changes or clinical outcomes. To study the influence of wireless self-monitoring program and patient activation measures on health behaviors, medication adherence, and blood pressure levels as well as control of blood pressure in hypertensive patients. We examined a subset of 95 hypertensive participants from a 6-month randomized controlled trial designed to determine the utility of a wireless self-monitoring program (n=52 monitoring program, n=43 control), which consisted of a blood pressure monitoring device connected with a mobile phone, reminders for self-monitoring, a Web-based disease management program, and a mobile app for monitoring and education, compared with the control group receiving a standard disease management program. Study participants provided measures of patient activation, health behaviors including smoking, drinking, and exercise, medication adherence, and blood pressure levels. We assessed the influence of wireless self-monitoring as a moderator of the relationship between patient activation and health behaviors, medication adherence, and control of blood pressure. Improvements in patient activation were associated with improvements in cigarette smoking (beta=-0.46, P<.001) and blood pressure control (beta=0.04, P=.02). This relationship was further strengthened in reducing cigarettes (beta=-0.60, P<.001), alcohol drinking (beta=-0.26, P=.01), and systolic (beta=-0.27, P=.02) and diastolic blood pressure (beta=-0.34, P=.007) at 6 months among individuals participating in the wireless self-monitoring program. No differences were observed with respect to medication adherence. Participation in a wireless self-monitoring program provides individuals motivated to improve their health management with an added benefit above and beyond that of motivation alone. Hypertensive individuals eager to change health behaviors are excellent candidates for mobile health self-monitoring.. ClinicalTrials.gov NCT01975428, https://clinicaltrials.gov/ct2/show/NCT01975428 (Archived by WebCite at http://www.webcitation.org/6iSO5OgOG).

Towards 24/7 continuous heart rate monitoring.

PubMed

Tarniceriu, Adrian; Parak, Jakub; Renevey, Philippe; Nurmi, Marko; Bertschi, Mattia; Delgado-Gonzalo, Ricard; Korhonen, Ilkka

2016-08-01

Heart rate (HR) and HR variability (HRV) carry rich information about physical activity, mental and physical load, physiological status, and health of an individual. When combined with activity monitoring and personalized physiological modelling, HR/HRV monitoring may be used for monitoring of complex behaviors and impact of behaviors and external factors on the current physiological status of an individual. Optical HR monitoring (OHR) from wrist provides a comfortable and unobtrusive method for HR/HRV monitoring and is better adhered by users than traditional ECG electrodes or chest straps. However, OHR power consumption is significantly higher than that for ECG based methods due to the measurement principle based on optical illumination of the tissue. We developed an algorithmic approach to reduce power consumption of the OHR in 24/7 HR trending. We use continuous activity monitoring and a fast converging frequency domain algorithm to derive a reliable HR estimate in 7.1s (during outdoor sports, in average) to 10.0s (during daily life). The method allows >80% reduction in power consumption in 24/7 OHR monitoring when average HR monitoring is targeted, without significant reduction in tracking accuracy.

Individually Unique Body Color Patterns in Octopus (Wunderpus photogenicus) Allow for Photoidentification

PubMed Central

Huffard, Christine L.; Caldwell, Roy L.; DeLoach, Ned; Gentry, David Wayne; Humann, Paul; MacDonald, Bill; Moore, Bruce; Ross, Richard; Uno, Takako; Wong, Stephen

2008-01-01

Studies on the longevity and migration patterns of wild animals rely heavily on the ability to track individual adults. Non-extractive sampling methods are particularly important when monitoring animals that are commercially important to ecotourism, and/or are rare. The use of unique body patterns to recognize and track individual vertebrates is well-established, but not common in ecological studies of invertebrates. Here we provide a method for identifying individual Wunderpus photogenicus using unique body color patterns. This charismatic tropical octopus is commercially important to the underwater photography, dive tourism, and home aquarium trades, but is yet to be monitored in the wild. Among the adults examined closely, the configurations of fixed white markings on the dorsal mantle were found to be unique. In two animals kept in aquaria, these fixed markings were found not to change over time. We believe another individual was photographed twice in the wild, two months apart. When presented with multiple images of W. photogenicus, volunteer observers reliably matched photographs of the same individuals. Given the popularity of W. photogenicus among underwater photographers, and the ease with which volunteers can correctly identify individuals, photo-identification appears to be a practical means to monitor individuals in the wild. PMID:19009019

Sensor placement on Canton Tower for health monitoring using asynchronous-climb monkey algorithm

NASA Astrophysics Data System (ADS)

Yi, Ting-Hua; Li, Hong-Nan; Zhang, Xu-Dong

2012-12-01

Heuristic optimization algorithms have become a popular choice for solving complex and intricate sensor placement problems which are difficult to solve by traditional methods. This paper proposes a novel and interesting methodology called the asynchronous-climb monkey algorithm (AMA) for the optimum design of sensor arrays for a structural health monitoring system. Different from the existing algorithms, the dual-structure coding method is designed and adopted for the representation of the design variables. The asynchronous-climb process is incorporated in the proposed AMA that can adjust the trajectory of each individual dynamically in the search space according to its own experience and other monkeys. The concept of ‘monkey king’ is introduced in the AMA, which reflects the Darwinian principle of natural selection and can create an interaction network to correctly guide the movement of other monkeys. Numerical experiments are carried out using two different objective functions by considering the Canton Tower in China with or without the antenna mast to evaluate the performance of the proposed algorithm. Investigations have indicated that the proposed AMA exhibits faster convergence characteristics and can generate sensor configurations superior in all instances when compared to the conventional monkey algorithm. For structures with stiffness mutation such as the Canton Tower, the sensor placement needs to be considered for each part separately.

System Report for the Optical Properties Monitor (OPM) Experiment

NASA Technical Reports Server (NTRS)

Hummer, L.

2001-01-01

This systems report describes how the Optical Properties Monitor (OPM) experiment was developed. Pertinent design parameters are discussed, along with mission information and system requirements to successfully complete the mission. Environmental testing was performed on the OPM to certify it for spaceflight. This testing included vibration, thermal vacuum, electromagnetic interference and conductance, and toxicity tests. Instrument and monitor subsystem performances, including the reflectometer, vacuum ultraviolet, total integrated scatter, atomic oxygen monitor, irradiance monitor, and molecular contamination monitor during the mission are discussed. The OPM experiment was launched aboard the Space Shuttle on mission STS-81 in January 1997 and transferred to the Mir space station. An extravehicular activity (EVA) was performed in April 1997 to attach the OPM experiment to the outside of the Mir/Shuttle Docking Module for space environment exposure. The OPM conducted in situ measurements of a number of material samples. These data may be found in the OPM Science Report. OPM was retrieved during an EVA in January 1998 and was returned to Earth on board the Space Shuttle on mission STS-89.

Fast and Accurate Exhaled Breath Ammonia Measurement

PubMed Central

Solga, Steven F.; Mudalel, Matthew L.; Spacek, Lisa A.; Risby, Terence H.

2014-01-01

This exhaled breath ammonia method uses a fast and highly sensitive spectroscopic method known as quartz enhanced photoacoustic spectroscopy (QEPAS) that uses a quantum cascade based laser. The monitor is coupled to a sampler that measures mouth pressure and carbon dioxide. The system is temperature controlled and specifically designed to address the reactivity of this compound. The sampler provides immediate feedback to the subject and the technician on the quality of the breath effort. Together with the quick response time of the monitor, this system is capable of accurately measuring exhaled breath ammonia representative of deep lung systemic levels. Because the system is easy to use and produces real time results, it has enabled experiments to identify factors that influence measurements. For example, mouth rinse and oral pH reproducibly and significantly affect results and therefore must be controlled. Temperature and mode of breathing are other examples. As our understanding of these factors evolves, error is reduced, and clinical studies become more meaningful. This system is very reliable and individual measurements are inexpensive. The sampler is relatively inexpensive and quite portable, but the monitor is neither. This limits options for some clinical studies and provides rational for future innovations. PMID:24962141

Establishing Networks to Lever Investments in Developing Capacity for Agricultural Monitoring: A GEOGLAM Perspective

NASA Astrophysics Data System (ADS)

Whitcraft, A. K.; Becker-Reshef, I.

2016-12-01

Since 2011, the Group on Earth Observations Global Agricultural Monitoring (GEOGLAM) Initiative has been working to strengthen the international community's capacity to use Earth observation (EO) data to derive timely, accurate, and transparent information on agriculture. A key component of GEOGLAM is the development of individual and institutional capacity for EO-based agricultural monitoring at multiple scales, from national to regional to global, in low-, middle-, and high-income countries. Despite the fact that the need for enhancing capacity is frequently acknowledged, there is little formal or informal literature documenting best practices for developing and implementing comprehensive capacity development strategies around Earth observations knowledge sharing. As a result, many projects and activities develop knowledge-sharing strategies on an ad hoc basis, and may be missing out on levering lessons, techniques, and toolsets already developed. In the past year, GEOGLAM has aimed to spur relationships and collaborations with capacity development initiatives and networks, toward sharing and documenting strategies and tactical experiences in this domain. This presentation will provide some perspective on challenges and opportunities encountered so far, from the GEOGLAM perspective, with the goal of continued dialogue and coordination with other session participants.

Infrared imaging based hyperventilation monitoring through respiration rate estimation

NASA Astrophysics Data System (ADS)

Basu, Anushree; Routray, Aurobinda; Mukherjee, Rashmi; Shit, Suprosanna

2016-07-01

A change in the skin temperature is used as an indicator of physical illness which can be detected through infrared thermography. Thermograms or thermal images can be used as an effective diagnostic tool for monitoring and diagnosis of various diseases. This paper describes an infrared thermography based approach for detecting hyperventilation caused due to stress and anxiety in human beings by computing their respiration rates. The work employs computer vision techniques for tracking the region of interest from thermal video to compute the breath rate. Experiments have been performed on 30 subjects. Corner feature extraction using Minimum Eigenvalue (Shi-Tomasi) algorithm and registration using Kanade Lucas-Tomasi algorithm has been used here. Thermal signature around the extracted region is detected and subsequently filtered through a band pass filter to compute the respiration profile of an individual. If the respiration profile shows unusual pattern and exceeds the threshold we conclude that the person is stressed and tending to hyperventilate. Results obtained are compared with standard contact based methods which have shown significant correlations. It is envisaged that the thermal image based approach not only will help in detecting hyperventilation but can assist in regular stress monitoring as it is non-invasive method.

Accelerometry: A feasible method to monitor physical activity during sub-acute rehabilitation of persons with stroke.

PubMed

Joseph, Conran; Strömbäck, Björn; Hagströmer, Maria; Conradsson, David

2018-05-08

To investigate the feasibility of using accelerometers to monitor physical activity in persons with stroke admitted to inpatient rehabilitation. Longitudinal observational study. Persons with stroke admitted to a specialized rehabilitation centre for sub-acute rehabilitation were recruited between August and December 2016. Volume and intensity of physical activity were assessed with accelerometers throughout the rehabilitation period. Indicators of feasibility included processes (recruitment, protocol adherence and participants' experiences) and scientific feasibility, which assessed the accelerometers' ability to detect change in physical activity among stroke survivors who ambulate independently and those who are dependent on a mobility device. Twenty-seven out of 31 eligible individuals took part in this study, with 23 (85%) completing it. In total, 432 days of rehabilitation were monitored and valid physical activity data were obtained for 408 days (94%). There were no indications that the measurement interfered with participants' ability to participate in rehabilitation. Despite the subjects' ambulation status, the number of steps and time spent in moderate-to-vigorous physical activity increased significantly across the first 18 days of rehabilitation, whereas sedentary time was unchanged. This study supports the feasibility of using accelerometers to capture physical activity behaviour in survivors of stroke during inpatient rehabilitation.

Space motion sickness monitoring experiment - Spacelab 1

NASA Technical Reports Server (NTRS)

Oman, Charles M.; Lichtenberg, Byron K.; Money, Kenneth E.

1990-01-01

A detailed firsthand report on symptoms and signs of space motion sickness and fluid shift observed by four specially trained crewmembers during Shuttle/Spacelab 1, launched on November 28, 1983 is presented. Results show that three crewmen experienced persistent overall discomfort and vomited repeatedly. Symptom pattern was generally similar to that seen in the individuals preflight, except that prodromalnausea was brief or absent in some cases. Symptoms were clearly modulated by head movement, were exacerbated by unfamiliar visual cues, and could be reduced by physical restraint providing contact cues around the body. The results support the view that space sickness is a form of motion sickness.

Experimental and numerical study on the strength of all-ceramic crowns

NASA Astrophysics Data System (ADS)

Lu, Chenglin; Zhang, Xiuyin; Zhang, Dongsheng

2008-11-01

Two types of sectioned tooth-like ceramic crowns (IPS Empress 2) were prepared along lingual-facial direction and the fracture process of crowns under contact load was directly monitored with the use of imaging system. The displacement filed resulted from digital image correlation indicate that the fracture mode of real crown is more complicated while the flat crown has the same rupture mode as described by other investigators. Meanwhile numerical simulation was also carried out to support the experiments. Stress distributions in individual layer and interface were presented. Results indicate that the presented experimental and numerical methods are efficient in studying the fracture mechanism of all-ceramic crowns.

Antipsychotic Use and Metabolic Monitoring in Individuals with Developmental Disabilities Served in a Medicaid Medical Home

ERIC Educational Resources Information Center

Ruiz, Lisa M.; Damron, Mackenzie; Jones, Kyle B.; Weedon, Dean; Carbone, Paul S.; Bakian, Amanda V.; Bilder, Deborah A.

2016-01-01

This study describes antipsychotic use and metabolic monitoring rates among individuals with developmental disabilities enrolled in a subspecialty medical home (N = 826). Four hundred ninety-nine participants (60.4%) were taking antipsychotics, which was associated with male gender (p = 0.01), intellectual disability with and without autism…

Design, Certification, and Deployment of the Colorimetric Water Quality Monitoring Kit (CWQMK)

NASA Technical Reports Server (NTRS)

Gazda, Daniel B.; Nolan, Daniel J.; Rutz, Jeff A.; Schultz, John R.; Siperko, Lorraine M.; Porter, Marc D.; Lipert, Robert J.; Flint, Stephanie M.; McCoy, J. Torin

2010-01-01

In August 2009, an experimental water quality monitoring kit based on Colorimetric Solid Phase Extraction (CSPE) technology was delivered to the International Space Station (ISS) aboard STS-128/17A. The kit, called the Colorimetric Water Quality Monitoring Kit (CWQMK), was flown and deployed as a Station Development Test Objective (SDTO) experiment on the ISS. The goal of the SDTO experiment is to evaluate the acceptability of CSPE technology for routine water quality monitoring on the ISS. This paper provides an overview of the SDTO experiment, as well as a detailed description of the CWQMK hardware and a summary of the testing and analysis conducted to certify the CWQMK for use on the ISS. The initial results obtained from the SDTO experiment are also reported and discussed in detail

Electromagnetic versus electrical coupling of personal frequency modulation (FM) receivers to cochlear implant sound processors.

PubMed

Schafer, Erin C; Romine, Denise; Musgrave, Elizabeth; Momin, Sadaf; Huynh, Christy

2013-01-01

Previous research has suggested that electrically coupled frequency modulation (FM) systems substantially improved speech-recognition performance in noise in individuals with cochlear implants (CIs). However, there is limited evidence to support the use of electromagnetically coupled (neck loop) FM receivers with contemporary CI sound processors containing telecoils. The primary goal of this study was to compare speech-recognition performance in noise and subjective ratings of adolescents and adults using one of three contemporary CI sound processors coupled to electromagnetically and electrically coupled FM receivers from Oticon. A repeated-measures design was used to compare speech-recognition performance in noise and subjective ratings without and with the FM systems across three test sessions (Experiment 1) and to compare performance at different FM-gain settings (Experiment 2). Descriptive statistics were used in Experiment 3 to describe output differences measured through a CI sound processor. Experiment 1 included nine adolescents or adults with unilateral or bilateral Advanced Bionics Harmony (n = 3), Cochlear Nucleus 5 (n = 3), and MED-EL OPUS 2 (n = 3) CI sound processors. In Experiment 2, seven of the original nine participants were tested. In Experiment 3, electroacoustic output was measured from a Nucleus 5 sound processor when coupled to the electromagnetically coupled Oticon Arc neck loop and electrically coupled Oticon R2. In Experiment 1, participants completed a field trial with each FM receiver and three test sessions that included speech-recognition performance in noise and a subjective rating scale. In Experiment 2, participants were tested in three receiver-gain conditions. Results in both experiments were analyzed using repeated-measures analysis of variance. Experiment 3 involved electroacoustic-test measures to determine the monitor-earphone output of the CI alone and CI coupled to the two FM receivers. The results in Experiment 1 suggested that both FM receivers provided significantly better speech-recognition performance in noise than the CI alone; however, the electromagnetically coupled receiver provided significantly better speech-recognition performance in noise and better ratings in some situations than the electrically coupled receiver when set to the same gain. In Experiment 2, the primary analysis suggested significantly better speech-recognition performance in noise for the neck-loop versus electrically coupled receiver, but a second analysis, using the best performance across gain settings for each device, revealed no significant differences between the two FM receivers. Experiment 3 revealed monitor-earphone output differences in the Nucleus 5 sound processor for the two FM receivers when set to the +8 setting used in Experiment 1 but equal output when the electrically coupled device was set to a +16 gain setting and the electromagnetically coupled device was set to the +8 gain setting. Individuals with contemporary sound processors may show more favorable speech-recognition performance in noise electromagnetically coupled FM systems (i.e., Oticon Arc), which is most likely related to the input processing and signal processing pathway within the CI sound processor for direct input versus telecoil input. Further research is warranted to replicate these findings with a larger sample size and to develop and validate a more objective approach to fitting FM systems to CI sound processors. American Academy of Audiology.

Processing of the WLCG monitoring data using NoSQL

NASA Astrophysics Data System (ADS)

Andreeva, J.; Beche, A.; Belov, S.; Dzhunov, I.; Kadochnikov, I.; Karavakis, E.; Saiz, P.; Schovancova, J.; Tuckett, D.

2014-06-01

The Worldwide LHC Computing Grid (WLCG) today includes more than 150 computing centres where more than 2 million jobs are being executed daily and petabytes of data are transferred between sites. Monitoring the computing activities of the LHC experiments, over such a huge heterogeneous infrastructure, is extremely demanding in terms of computation, performance and reliability. Furthermore, the generated monitoring flow is constantly increasing, which represents another challenge for the monitoring systems. While existing solutions are traditionally based on Oracle for data storage and processing, recent developments evaluate NoSQL for processing large-scale monitoring datasets. NoSQL databases are getting increasingly popular for processing datasets at the terabyte and petabyte scale using commodity hardware. In this contribution, the integration of NoSQL data processing in the Experiment Dashboard framework is described along with first experiences of using this technology for monitoring the LHC computing activities.

Reality Monitoring and Feedback Control of Speech Production Are Related Through Self-Agency.

PubMed

Subramaniam, Karuna; Kothare, Hardik; Mizuiri, Danielle; Nagarajan, Srikantan S; Houde, John F

2018-01-01

Self-agency is the experience of being the agent of one's own thoughts and motor actions. The intact experience of self-agency is necessary for successful interactions with the outside world (i.e., reality monitoring) and for responding to sensory feedback of our motor actions (e.g., speech feedback control). Reality monitoring is the ability to distinguish internally self-generated information from outside reality (externally-derived information). In the present study, we examined the relationship of self-agency between lower-level speech feedback monitoring (i.e., monitoring what we hear ourselves say) and a higher-level cognitive reality monitoring task. In particular, we examined whether speech feedback monitoring and reality monitoring were driven by the capacity to experience self-agency-the ability to make reliable predictions about the outcomes of self-generated actions. During the reality monitoring task, subjects made judgments as to whether information was previously self-generated (self-agency judgments) or externally derived (external-agency judgments). During speech feedback monitoring, we assessed self-agency by altering environmental auditory feedback so that subjects listened to a perturbed version of their own speech. When subjects heard minimal perturbations in their auditory feedback while speaking, they made corrective responses, indicating that they judged the perturbations as errors in their speech output. We found that self-agency judgments in the reality-monitoring task were higher in people who had smaller corrective responses ( p = 0.05) and smaller inter-trial variability ( p = 0.03) during minimal pitch perturbations of their auditory feedback. These results provide support for a unitary process for the experience of self-agency governing low-level speech control and higher level reality monitoring.

ENVIRONMENTAL CHEMICAL MONITORING IN THE U.S.

EPA Science Inventory

Chemical monitoring of the environment is performed in the United States by Federal and State agencies, local governments, industries, organizations, and private individuals. The major reasons for monitoring are for compliance with laws and regulations, investigation of suspec...

Trading shallow safety for deep sleep: Juvenile green turtles select deeper resting sites as they grow

USGS Publications Warehouse

Hart, Kristen M.; White, Connor F.; Iverson, Autumn R.; Whitney, Nick

2016-01-01

To better protect endangered green sea turtles Chelonia mydas, a more thorough understanding of the behaviors of each life stage is needed. Although dive profile analyses obtained using time-depth loggers have provided some insights into habitat use, recent work has shown that more fine-scale monitoring of body movements is needed to elucidate physical activity patterns. We monitored 11 juvenile green sea turtles with tri-axial acceleration data loggers in their foraging grounds in Dry Tortugas National Park, Florida, USA, for periods ranging from 43 to 118 h (mean ± SD: 72.8 ± 27.3 h). Approximately half of the individuals (n = 5) remained in shallow (overall mean depth less than 2 m) water throughout the experiment, whereas the remaining individuals (n = 6) made excursions to deeper (4 to 27 m) waters, often at night. Despite these differences in depth use, acceleration data revealed a consistent pattern of diurnal activity and nocturnal resting in most individuals. Nocturnal depth differences thus do not appear to represent differences in behavior, but rather different strategies to achieve the same behavior: rest. We calculated overall dynamic body acceleration (ODBA) to assess the relative energetic cost of each behavioral strategy in an attempt to explain the differences between them. Animals in deeper water experienced longer resting dives, more time resting per hour, and lower mean hourly ODBA. These results suggest that resting in deeper water provides energetic benefits that outweigh the costs of transiting to deep water and a potential increased risk of predation.

Acceptability and feasibility of the 'DASH for Asthma' intervention in a randomized controlled trial pilot study.

PubMed

Blonstein, Andrea C; Lv, Nan; Camargo, Carlos A; Wilson, Sandra R; Buist, A Sonia; Rosas, Lisa G; Strub, Peg; Ma, Jun

2016-08-01

'DASH for Asthma' (n 90) was a 6-month randomized controlled trial that demonstrated potential benefits of a DASH (Dietary Approaches to Stop Hypertension) behavioural intervention for improving diet quality and asthma control by comparing intervention to usual care in adults with uncontrolled asthma. The present study examined acceptability and feasibility of the intervention from the perspective of intervention participants and lifestyle coaches. Grounded in Social Cognitive Theory, the 3-month intensive stage, including three individual and eight group sessions, focused on diet modifications and behavioural self-regulation. The 3-month maintenance stage contained telephone consultations. Participants and lifestyle coaches completed surveys including 5-point Likert scales and open-ended questions. We analysed data using descriptive and inductive content analyses. Forty-six intervention participants (survey response rate was 65-72 %) and two lifestyle coaches. Participants and lifestyle coaches were highly satisfied (all mean ratings >4) with individual and group sessions. Participants identified mastery of knowledge and skills (awareness, goal setting, self-monitoring, problem solving), social learning (class members sharing experiences and ideas) and good coaching skills (reflective listening, empathy, motivational counselling) as important contributors to self-efficacy and programme satisfaction. Participants also valued personalized feedback received in individual sessions. Lifestyle coaches viewed participant engagement as a facilitator to effective sessions. Finally, participants and lifestyle coaches identified food tasting as beneficial for observational learning and facilitation of participant engagement. High class attendance and self-monitoring rate also reflected the high engagement among participants. The DASH behavioural intervention was feasible and highly acceptable to participants with uncontrolled asthma and lifestyle coaches.

Studies of the Interactions Between Vestibular Function and Tactual Orientation Display Systems

NASA Technical Reports Server (NTRS)

Cholewiak, Roger W.; Reschke, Millard F.

1997-01-01

When humans experience conditions in which internal vestibular cues to movement or spatial location are challenged or contradicted by external visual information, the result can be spatial disorientation, often leading to motion sickness. Spatial disorientation can occur in any situation in which the individual is passively moved in the environment, but is most common in automotive, aircraft, or undersea travel. Significantly, the incidence of motion sickness in space travel is great: The majority of individuals in Shuttle operations suffer from the syndrome. Even after the space-sickness-producing influences of spatial disorientation dissipate, usually within several days, there are other situations in which, because of the absence of reliable or familiar vestibular cues, individuals in space still experience disorientation, resulting in a reliance on the already preoccupied sense of vision. One possible technique to minimize the deleterious effects of spatial disorientation might be to present attitude information (including orientation, direction, and motion) through another less-used sensory modality - the sense of touch. Data from experiences with deaf and blind persons indicate that this channel can provide useful communication and mobility information on a real-time basis. More recently, technologies have developed to present effective attitude information to pilots in situations in which dangerously ambiguous and conflicting visual and vestibular sensations occur. This summers project at NASA-Johnson Space Center will evaluate the influence of motion-based spatial disorientation on the perception of tactual stimuli representing veridical position and orientation information, presented by new dynamic vibrotactile array display technologies. In addition, the possibility will be explored that tactile presentations of motion and direction from this alternative modality might be useful in mitigating or alleviating spatial disorientation produced by multi-axis rotatory systems, monitored by physiological recording techniques developed at JSC.

A Centralized Display for Mission Monitoring

NASA Technical Reports Server (NTRS)

Trujillo, Anna C.

2004-01-01

Humans traditionally experience a vigilance decrement over extended periods of time on reliable systems. One possible solution to aiding operators in monitoring is to use polar-star displays that will show deviations from normal in a more salient manner. The primary objectives of this experiment were to determine if polar-star displays aid in monitoring and preliminary diagnosis of the aircraft state. This experiment indicated that the polar-star display does indeed aid operators in detecting and diagnosing system events. Subjects were able to notice system events earlier and they subjectively reported the polar-star display helped them in monitoring, noticing an event, and diagnosing an event. Therefore, these results indicate that the polar-star display used for monitoring and preliminary diagnosis improves performance in these areas for system related events.

Adaptive online monitoring for ICU patients by combining just-in-time learning and principal component analysis.

PubMed

Li, Xuejian; Wang, Youqing

2016-12-01

Offline general-type models are widely used for patients' monitoring in intensive care units (ICUs), which are developed by using past collected datasets consisting of thousands of patients. However, these models may fail to adapt to the changing states of ICU patients. Thus, to be more robust and effective, the monitoring models should be adaptable to individual patients. A novel combination of just-in-time learning (JITL) and principal component analysis (PCA), referred to learning-type PCA (L-PCA), was proposed for adaptive online monitoring of patients in ICUs. JITL was used to gather the most relevant data samples for adaptive modeling of complex physiological processes. PCA was used to build an online individual-type model and calculate monitoring statistics, and then to judge whether the patient's status is normal or not. The adaptability of L-PCA lies in the usage of individual data and the continuous updating of the training dataset. Twelve subjects were selected from the Physiobank's Multi-parameter Intelligent Monitoring for Intensive Care II (MIMIC II) database, and five vital signs of each subject were chosen. The proposed method was compared with the traditional PCA and fast moving-window PCA (Fast MWPCA). The experimental results demonstrated that the fault detection rates respectively increased by 20 % and 47 % compared with PCA and Fast MWPCA. L-PCA is first introduced into ICU patients monitoring and achieves the best monitoring performance in terms of adaptability to changes in patient status and sensitivity for abnormality detection.

The strategic control of prospective memory monitoring in response to complex and probabilistic contextual cues.

PubMed

Bugg, Julie M; Ball, B Hunter

2017-07-01

Participants use simple contextual cues to reduce deployment of costly monitoring processes in contexts in which prospective memory (PM) targets are not expected. This study investigated whether this strategic monitoring pattern is observed in response to complex and probabilistic contextual cues. Participants performed a lexical decision task in which words or nonwords were presented in upper or lower locations on screen. The specific condition was informed that PM targets ("tor" syllable) would occur only in words in the upper location, whereas the nonspecific condition was informed that targets could occur in any location or word type. Context was blocked such that word type and location changed every 8 trials. In Experiment 1, the specific condition used the complex contextual cue to reduce monitoring in unexpected contexts relative to the nonspecific condition. This pattern largely was not evidenced when the complex contextual cue was probabilistic (Experiment 2). Experiment 3 confirmed that strategic monitoring is observed for a complex cue that is deterministic, but not one that is probabilistic. Additionally, Experiments 1 and 3 demonstrated a disadvantage associated with strategic monitoring-namely, that the specific condition was less likely to respond to a PM target in an unexpected context. Experiment 3 provided evidence that this disadvantage is attributable to impaired noticing of the target. The novel findings suggest use of a complex contextual cue per se is not a boundary condition for the strategic, context-specific allocation of monitoring processes to support prospective remembering; however, strategic monitoring is constrained by the predictive utility of the complex contextual cue.

Integrating smart-phone based momentary location tracking with fixed site air quality monitoring for personal exposure assessment.

PubMed

Su, Jason G; Jerrett, Michael; Meng, Ying-Ying; Pickett, Melissa; Ritz, Beate

2015-02-15

Epidemiological studies investigating relationships between environmental exposures from air pollution and health typically use residential addresses as a single point for exposure, while environmental exposures in transit, at work, school or other locations are largely ignored. Personal exposure monitors measure individuals' exposures over time; however, current personal monitors are intrusive and cannot be operated at a large scale over an extended period of time (e.g., for a continuous three months) and can be very costly. In addition, spatial locations typically cannot be identified when only personal monitors are used. In this paper, we piloted a study that applied momentary location tracking services supplied by smart phones to identify an individual's location in space-time for three consecutive months (April 28 to July 28, 2013) using available Wi-Fi networks. Individual exposures in space-time to the traffic-related pollutants Nitrogen Oxides (NOX) were estimated by superimposing an annual mean NOX concentration surface modeled using the Land Use Regression (LUR) modeling technique. Individual's exposures were assigned to stationary (including home, work and other stationary locations) and in-transit (including commute and other travel) locations. For the individual, whose home/work addresses were known and the commute route was fixed, it was found that 95.3% of the time, the individual could be accurately identified in space-time. The ambient concentration estimated at the home location was 21.01 ppb. When indoor/outdoor infiltration, indoor sources of air pollution and time spent outdoors were taken into consideration, the individual's cumulative exposures were 28.59 ppb and 96.49 ppb, assuming a respective indoor/outdoor ratio of 1.33 and 5.00. Integrating momentary location tracking services with fixed-site field monitoring, plus indoor-outdoor air exchange calibration, makes exposure assessment of a very large population over an extended time period feasible. Copyright © 2014 Elsevier B.V. All rights reserved.

Application of Computers for Experiment Design, Data Acquisition, and Analysis in the Chemistry Laboratory

DTIC Science & Technology

1990-05-01

Obtain Thermistor Operating Characteristics ................................. 82 25. Ag+/Ci" Thermometric Titration ........................... 85 26...Experiment Program for Thermometric Titrations ............... 85 27. Appearance of the Spreadsheet in the Analysis Mode ............ 86 28...rate experiments, carbon dioxide exhalation monitoring, stream turbidity measurement, photosynthesis monitoring, pendulum timing, thermometric titrations

Development of a three-mirror anastigmat telescope for the GERB experiment

NASA Astrophysics Data System (ADS)

Gloesener, Pierre; Quertemont, Eric; Flebus, Carlo

2017-11-01

The GERB experiment, on-board Meteosat Second Generation, aims at monitoring the Earth radiation budget within a broad spectral range (0.32 -30 ‡m). This paper outlines the development of the GERB imaging subsystem, a f/2 three-mirror anastigmat telescope with a 18° x 0,28° rectangular field-of-view. The telescope is an all-aluminium design, comprising a primary off-axis elliptical mirror and two spherical ones, with a largest size of 100 mm. After integration and environmental testing, its global on-axis imaging performance reached 0,45 ‡ rms at 633 nm for an optical design value of 0,27 ‡ rms. The global opto-mechanical tolerance analysis of the design phase defined an integration sequence able to keep the individual alignment of each mirror within the accuracy needed to ascertain the whole telescope quality.

Discriminative facility and its role in the perceived quality of interactional experiences.

PubMed

Cheng, C; Chiu, C Y; Hong, Y Y; Cheung, J S

2001-10-01

Discriminative facility refers to an individual's sensitivity to subtle cues about the psychological meaning of a situation. This research aimed at examining (a) the conceptual distinctiveness of discriminative facility, (b) the situation-appropriate aspect of this construct, and (c) the relationship between discriminative facility and interpersonal experiences. Discriminative facility was assessed by a new measure of situation-appropriate behaviors across a variety of novel stressful situations. Results from study 1 showed that discriminative facility had weak positive relationships with cognitive complexity and nonsignificant relationships with self-monitoring and social desirability, indicating that discriminative facility is a unique construct. Results from Study 2 revealed that higher levels of discriminative facility were associated with higher levels of perceived social support and a greater number of pleasant interpersonal events experienced, thus providing support for the theoretical proposition that discriminative facility is an aspect of social intelligence.

Collaboration: an innovative education/business partnership.

PubMed

Sackett, K; Hendricks, C; Pope, R

2000-01-01

Healthy People 2010 initiatives encourage the collaborative partnership goals described in this article. The partnership developed between a UB School of Nursing faculty member, her students, and several case managers at Health-Now Now has been a richly rewarding experience. The opportunities afforded by this partnership have expanded experiences for faculty, students, and case managers in a managed care environment. This partnership has enabled participants to initiate practical, cost-effective methods for improving community-based services. These partnerships should yield significant changes in health behaviors and health outcomes among the American public. Valanis states it most succinctly: "The nurse of the 21st century must innovate, coordinate, and monitor services for populations within the health care system in which she works and interacts with crucial services outside the system. Her or his patient is not only an individual or even the family but the entire community."

Eye Movement Monitoring in the Study of Silent Reading.

ERIC Educational Resources Information Center

McConkie, George W.

Eye movement monitoring is useful both in the control of experiments on reading and as a source of data. Experiments using eye monitoring techniques have helped develop the following conclusions about the reading process: the region of text read during a fixation is quite small and asymmetric to the right of the center of vision, successive…

Comparison of WinSLAMM Modeled Results with Monitored Biofiltration Data

EPA Science Inventory

The US EPA’s Green Infrastructure Demonstration project in Kansas City incorporates both small scale individual biofiltration device monitoring, along with large scale watershed monitoring. The test watershed (100 acres) is saturated with green infrastructure components (includin...

INTEGRATED STATE-FEDERAL PARTNERSHIP FOR AQUATIC RESOURCE MONITORING

EPA Science Inventory

Fifteen federal agencies, 50 states, cities, counties, and 800-1000 volunteer organizations conduct aquatic resource monitoring in the United States. Most aquatic monitoring is project-specific focusing on individual locations or watersheds. The Clean Water Act requires states ...

Characterization of blocks impacts from acoustic emissions: insights from laboratory experiments

NASA Astrophysics Data System (ADS)

Farin, Maxime; Mangeney, Anne; de Rosny, Julien; Toussaint, Renaud; Shapiro, Nikolaï

2014-05-01

Rockfalls, debris flows and rock avalanches represent a major natural hazard for the population in mountainous, volcanic and coastal areas but their direct observation on the field is very dangerous. Recent studies showed that gravitational instabilities can be detected and characterized (volume, duration,...) thanks to the seismic signal they generate. In an avalanche, individual block bouncing and rolling on the ground are expected to generated signals of higher frequencies than the main flow spreading. The identification of the time/frequency signature of individual blocks in the recorded signal remains however difficult. Laboratory experiments were conducted to investigate the acoustic signature of diverse simple sources corresponding to grains falling over thin plates of plexiglas and glass and over rock blocks. The elastic energy emitted by a single bouncing bead into the support was first quantitatively estimated and compared to the potential energy of fall and to the potential energy change during the shock. We obtained simple scaling laws relating the impactor characteristics (size, height of fall, material,...) to the elastic energy and spectral content. Next, we consider the collapse of granular columns made of steel spherical beads onto hard substrates. Initially, these columns were held by a magnetic field allowing to suppress suddenly the cohesion between the beads, and thus to minimize friction effects that would arise from side walls. We varied systematically the column volume, the column aspect ratio (height over length) and the grain size. This is shown to affect the signal envelope and frequency content. In the experiments, accelerometers (1 Hz to 56 kHz) were used to record the signals in a wide frequency range. The experiments were also monitored optically using fast cameras. Eventually, we looked at what types of features in the signal are affected by individual impacts, rolling of beads or by the large scale geometry of the avalanche.

Characterization of blocks impacts from elastic waves: insights from laboratory experiments

NASA Astrophysics Data System (ADS)

Farin, M.; Mangeney, A.; Toussaint, R.; De Rosny, J.; Shapiro, N.

2013-12-01

Rockfalls, debris flows and rock avalanches constitute a major natural hazard for the population in mountainous, volcanic and coastal areas but their direct observation on the field is very dangerous. Recent studies showed that gravitational instabilities can be detected and characterized (volume, duration,...) thanks to the seismic signal they generate. In an avalanche, individual block bouncing and rolling on the ground are expected to generated signals of higher frequencies than the main flow spreading. The identification of the time/frequency signature of individual blocks in the recorded signal remains however difficult. Laboratory experiments were conducted to investigate the acoustic signature of diverse simple sources corresponding to grains falling over thin plates of plexiglas and rock blocks. The elastic energy emitted by a single bouncing steel bead into the support was first quantitatively estimated and compared to the potential energy of fall and to the potential energy change during the shock. Next, we consider the collapse of granular columns made of steel spherical beads onto hard substrates. Initially, these columns were held by a magnetic field allowing to suppress suddenly the cohesion between the beads, and thus to minimize friction effects that would arise from side walls. We varied systematically the column volume, the column aspect ratio (height over length) and the grain size. This is shown to affect the signal envelope and frequency content. In the experiments, two types of acoustic sensors were used to record the signals in a wide frequency range: accelerometers (1 Hz to 56 kHz) and piezoelectric sensors (100 kHz to 1 MHz). The experiments were also monitored optically using fast cameras. We developed a technique to use quantitatively both types of sensors to evaluate the elastic energy emitted by the sources. Eventually, we looked at what types of features in the signal are affected by individual shocks or by the large scale geometry of the avalanche.

The US Navy’s Helicopter Integrated Diagnostics System (HIDS) Program: Power Drive Train Crack Detection Diagnostics and Prognostics Life Usage Monitoring and Damage Tolerance; Techniques, Methodologies, and Experiences

DTIC Science & Technology

2000-02-01

HIDS] Program: Power Drive Train Crack Detection Diagnostics and Prognostics ife Usage Monitoring and Damage Tolerance; Techniques, Methodologies, and...and Prognostics , Life Usage Monitoring , and Damage Tolerance; Techniques, Methodologies, and Experiences Andrew Hess Harrison Chin William Hardman...continuing program and deployed engine monitoring systems in fixed to evaluate helicopter diagnostic, prognostic , and wing aircraft, notably on the A

Towards improved biomonitoring tools for an intensified sustainable multi-use environment.

PubMed

van der Meer, Jan Roelof

2016-09-01

The increasing use of our environment for multiple contrasting activities (e.g. fisheries, tourism) will have to be accompanied by improved monitoring of environmental quality, to avoid transboundary conflicts and ensure long-term sustainable intensified usage. Biomonitoring approaches are appropriate for this, since they can integrate biological effects of environmental exposure rather than measure individual compound concentrations. Recent advances in biomonitoring concepts and tools focus on single-cell assays and purified biological components that can be miniaturized and integrated in automated systems. Despite these advances, we are still very far from being able to deploy bioassays routinely in environmental monitoring, mostly because of lack of experience in interpreting responses and insufficient robustness of the biosensors for their environmental application. Further future challenges include broadening the spectrum of detectable compounds by biosensors, accelerate response times and combining sample pretreatment strategies with bioassays. © 2016 The Author. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

Structural health monitoring and probability of detection estimation

NASA Astrophysics Data System (ADS)

Forsyth, David S.

2016-02-01

Structural health monitoring (SHM) methods are often based on nondestructive testing (NDT) sensors and are often proposed as replacements for NDT to lower cost and/or improve reliability. In order to take advantage of SHM for life cycle management, it is necessary to determine the Probability of Detection (POD) of the SHM system just as for traditional NDT to ensure that the required level of safety is maintained. Many different possibilities exist for SHM systems, but one of the attractive features of SHM versus NDT is the ability to take measurements very simply after the SHM system is installed. Using a simple statistical model of POD, some authors have proposed that very high rates of SHM system data sampling can result in high effective POD even in situations where an individual test has low POD. In this paper, we discuss the theoretical basis for determining the effect of repeated inspections, and examine data from SHM experiments against this framework to show how the effective POD from multiple tests can be estimated.

Real-time action recognition using a multilayer descriptor with variable size

NASA Astrophysics Data System (ADS)

Alcantara, Marlon F.; Moreira, Thierry P.; Pedrini, Helio

2016-01-01

Video analysis technology has become less expensive and more powerful in terms of storage resources and resolution capacity, promoting progress in a wide range of applications. Video-based human action detection has been used for several tasks in surveillance environments, such as forensic investigation, patient monitoring, medical training, accident prevention, and traffic monitoring, among others. We present a method for action identification based on adaptive training of a multilayer descriptor applied to a single classifier. Cumulative motion shapes (CMSs) are extracted according to the number of frames present in the video. Each CMS is employed as a self-sufficient layer in the training stage but belongs to the same descriptor. A robust classification is achieved through individual responses of classifiers for each layer, and the dominant result is used as a final outcome. Experiments are conducted on five public datasets (Weizmann, KTH, MuHAVi, IXMAS, and URADL) to demonstrate the effectiveness of the method in terms of accuracy in real time.

Remote monitoring of fish in small streams: A unified approach using PIT tags

USGS Publications Warehouse

Zydlewski, G.B.; Horton, G.; Dubreuil, T.; Letcher, B.; Casey, S.; Zydlewski, Joseph D.

2006-01-01

Accurate assessments of fish populations are often limited by re-observation or recapture events. Since the early 1990s, passive integrated transponders (PIT tags) have been used to understand the biology of many fish species. Until recently, PIT applications in small streams have been limited to physical recapture events. To maximize recapture probability, we constructed PIT antenna arrays in small streams to remotely detect individual fish. Experiences from two different laboratories (three case studies) allowed us to develop a unified approach to applying PIT technology for enhancing data assessments. Information on equipment, its installation, tag considerations, and array construction is provided. Theoretical and practical definitions are introduced to standardize metrics for assessing detection efficiency. We demonstrate how certain conditions (stream discharge, vibration, and ambient radio frequency noise) affect the detection efficiency and suggest that by monitoring these conditions, expectations of efficiency can be modified. We emphasize the importance of consistently estimating detection efficiency for fisheries applications.

High-resolution Interferometer Sounder (HIS), phase 2

NASA Technical Reports Server (NTRS)

1988-01-01

The High-resolution Interferometer Sounder (HIS) was successfully built, tested, and flight proven on the NASA U-2/ER-2 high altitude aircraft. The HIS demonstration has shown that, by using the technology of Fourier Transform Spectroscopy (FTS), it is possible to measure the spectrum of upwelling infrared radiance needed for temperature and humidity sounding with high spectral resolution and high radiometric precision. By resolving individual carbon dioxide lines, the retrieved temperature profiles have vertical resolutions of 1 to 2 km and RMS errors less than 1 C, about 2 to 4 times better than possible with current sounders. Implementing this capability on satellite sounders will greatly enhance the dynamical information content of temperature measurements from space. The aircraft model HIS is now a resource which should be used to support field experiments in mesoscale meteorology, to monitor trace gas concentrations and to better understand their effects on climate, to monitor the surface radiation budget and the radiative effects of clouds, and to collect data for research into retrieval techniques, especially under partially cloudy conditions.

Development of a Mobile Phone App to Support Self-Monitoring of Emotional Well-Being: A Mental Health Digital Innovation

PubMed Central

2016-01-01

Background Emotional well-being is a primary component of mental health and well-being. Monitoring changes in emotional state daily over extended periods is, however, difficult using traditional methodologies. Providing mental health support is also challenging when approximately only 1 in 2 people with mental health issues seek professional help. Mobile phone technology offers a sustainable means of enhancing self-management of emotional well-being. Objective This paper aims to describe the development of a mobile phone tool designed to monitor emotional changes in a natural everyday context and in real time. Methods This evidence-informed mobile phone app monitors emotional mental health and well-being, and it provides links to mental health organization websites and resources. The app obtains data via self-report psychological questionnaires, experience sampling methodology (ESM), and automated behavioral data collection. Results Feedback from 11 individuals (age range 16-52 years; 4 males, 7 females), who tested the app over 30 days, confirmed via survey and focus group methods that the app was functional and usable. Conclusions Recommendations for future researchers and developers of mental health apps to be used for research are also presented. The methodology described in this paper offers a powerful tool for a range of potential mental health research studies and provides a valuable standard against which development of future mental health apps should be considered. PMID:27881358

Blood glucose monitoring skills in children with Type I diabetes.

PubMed

Perwien, A R; Johnson, S B; Dymtrow, D; Silverstein, J

2000-06-01

While blood glucose monitoring has become increasingly important in diabetes care, studies have yet to address the accuracy of youngsters' performance of blood glucose testing with current reflectance meters. The present study examined testing skills and predictors of accurate testing skills in a sample of 7-14-year-old children attending a summer camp for youth with diabetes (n=266). A 15-item behavior observational skill test was used to assess accuracy of blood glucose monitoring skills with reflectance meters. Accurate performance of individual skills ranged between 14.6% and 99.6% for the sample. However, a number of children made critical errors (errors that were likely to lead to inaccurate blood glucose testing results). When duration of diabetes and metabolic control were controlled, female gender, older age, experience with a particular meter, and absence of hypoglycemia at the time of testing were positively associated with accurate skill performance. Findings suggest that younger children, children using a new blood glucose testing meter, and children suspected of having hypoglycemia should be supervised and observed when testing. Although all young children should be supervised when blood glucose testing, boys may need closer supervision until an older age than girls. This study underscores the need for health care providers to periodically observe children's blood glucose monitoring techniques to assure accurate testing habits and to correct problematic testing behaviors.

Contamination of estuaries from failing septic tank systems: difficulties in scaling up from monitored individual systems to cumulative impact.

PubMed

Geary, Phillip; Lucas, Steven

2018-02-03

Aquaculture in many coastal estuaries is threatened by diffuse sources of runoff from different land use activities. The poor performance of septic tank systems (STS), as well as runoff from agriculture, may contribute to the movement of contaminants through ground and surface waters to estuaries resulting in oyster contamination, and following their consumption, impacts to human health. In monitoring individual STS in sensitive locations, it is possible to show that nutrients and faecal contaminants are transported through the subsurface in sandy soils off-site with little attenuation. At the catchment scale however, there are always difficulties in discerning direct linkages between failing STS and water contamination due to processes such as effluent dilution, adsorption, precipitation and vegetative uptake. There is often substantial complexity in detecting and tracing effluent pathways from diffuse sources to water bodies in field studies. While source tracking as well as monitoring using tracers may assist in identifying potential pathways from STS to surface waters and estuaries, there are difficulties in scaling up from monitored individual systems to identify their contribution to the cumulative impact which may be apparent at the catchment scale. The processes which may be obvious through monitoring and dominate at the individual scale may be masked and not readily discernible at the catchment scale due to impacts from other land use activities.

An Experiment to Search for Systematic Effects in Long-Lived Radioactive Decays

NASA Astrophysics Data System (ADS)

Reuter, Cassie A.

Franz Zwicky first discovered "Dunkle Materie," or "Dark Matter" over 100 years ago, when he realized galaxy clusters must consist predominately of non-luminous matter. Since then, mounting evidence, has shown that a paltry 4% of the energy density of the universe is baryonic matter. We realize that the energy density of the universe is, in fact, dominated by dark matter and dark energy. Despite the evidence for dark matter, there is a long-standing discrepancy in the interpretation of results from direct dark matter experiments. The Italian DArk MAtter project (DAMA) claims to have discovered WIMPs, a particular variety of dark matter, since 1999. However, other direct detection experiments, provide results that directly contradict DAMA's claims. For years, the dark matter community has worked to reconcile the two opposing sets of results through improved experiments in direct detection and alternative Dark Matter models. This thesis outlines the Modulation Experiment, which is designed to identify and determine possible systematic sources of error that could explain the annually modulating signal attributed to Dark Matter by DAMA. We present a dedicated experiment for the long-term measurement of gamma emissions resulting from beta decays that provides high-quality data and allows for the identification of systematic influences. Up to 16 sources are monitored redundantly by 32 3x3" NaI(Tl) detectors in four separate setups across three continents. In each setup, monitoring of environmental and operational conditions facilitates correlation studies. The deadtime-free performance of the data acquisition system is confirmed and monitored by LED pulsers. Waveforms of all events are recorded individually, enabling a study of time-dependent effects spanning microseconds to years, using both time-binned and unbinned analyses. In this thesis, we show that the experiment is successfully acquiring data, and environmental effects are well-understood. Because of the experimental design, the Modulation Experiment is particularly well-suited to monitor decay rates of various isotopes. Though decay rates are generally considered to be Poisson processes, standards offices such as the National Institute of Standards (NIST) and Physikalisch-Technische Bundesanstalt (PTB) have reported annually modulating rates due to an unknown influence. Some scientists hypothesize that these effects may be due to a solar neutrino influence. Furthermore, some scientists have also examined a potential link from solar effects (e.g. flares and storms) to discrepancies in decay rate. However, these effects may simply be the by-products of some seasonal effects. This thesis explores the reported claims of decay rate modulation, and limits annual modulation amplitudes to < 5.95x10-5 for Ti-44, 1.46x10-4 for Co-60, and 1.8x10-4 Cs-137 at a 3sigma confidence level. No additional periodicities were found to be statistically significant. The Modulation experiment is beginning to explore the true nature of the impact of systematic effects on the measured decay rate. As data continues to be collected and more setups come online, we will be able to lower statistical uncertainties on measurements the half life, measure or set further limits on time-dependent modulations and search for correlations between locations.

Are Nomothetic or Ideographic Approaches Superior in Predicting Daily Exercise Behaviors?

PubMed

Cheung, Ying Kuen; Hsueh, Pei-Yun Sabrina; Qian, Min; Yoon, Sunmoo; Meli, Laura; Diaz, Keith M; Schwartz, Joseph E; Kronish, Ian M; Davidson, Karina W

2017-01-01

The understanding of how stress influences health behavior can provide insights into developing healthy lifestyle interventions. This understanding is traditionally attained through observational studies that examine associations at a population level. This nomothetic approach, however, is fundamentally limited by the fact that the environment- person milieu that constitutes stress exposure and experience can vary substantially between individuals, and the modifiable elements of these exposures and experiences are individual-specific. With recent advances in smartphone and sensing technologies, it is now possible to conduct idiographic assessment in users' own environment, leveraging the full-range observations of actions and experiences that result in differential response to naturally occurring events. The aim of this paper is to explore the hypothesis that an ideographic N-of-1 model can better capture an individual's stress- behavior pathway (or the lack thereof) and provide useful person-specific predictors of exercise behavior. This paper used the data collected in an observational study in 79 participants who were followed for up to a 1-year period, wherein their physical activity was continuously and objectively monitored by actigraphy and their stress experience was recorded via ecological momentary assessment on a mobile app. In addition, our analyses considered exogenous and environmental variables retrieved from public archive such as day in a week, daylight time, temperature and precipitation. Leveraging the multiple data sources, we developed prediction algorithms for exercise behavior using random forest and classification tree techniques using a nomothetic approach and an N-of-1 approach. The two approaches were compared based on classification errors in predicting personalized exercise behavior. Eight factors were selected by random forest for the nomothetic decision model, which was used to predict whether a participant would exercise on a particular day. The predictors included previous exercise behavior, emotional factors (e.g., midday stress), external factors such as weather (e.g., temperature), and self-determination factors (e.g., expectation of exercise). The nomothetic model yielded an average classification error of 36%. The ideographic N-of-1 models used on average about two predictors for each individual, and had an average classification error of 25%, which represented an improvement of 11 percentage points. Compared to the traditional one-size-fits-all, nomothetic model that generalizes population-evidence for individuals, the proposed N-of-1 model can better capture the individual difference in their stressbehavior pathways. In this paper, we demonstrate it is feasible to perform personalized exercise behavior prediction, mainly made possible by mobile health technology and machine learning analytics. Schattauer GmbH.

In the loop: Practices of self-monitoring from accounts by trial participants

PubMed Central

Lynch, Rebecca; Cohn, Simon

2015-01-01

Self-monitoring, by which individuals record and appraise ongoing information about the status of their body in order to improve their health, has been a key element in the personal management of conditions such as diabetes, but it is now also increasingly used in relation to health-associated behaviours. The introduction of self-monitoring as an intervention to change behaviour is intended to provide feedback that can be used by individuals to both assess their status and provide ongoing support towards a goal that may be formally set or remains implicit. However, little attention has been paid to how individuals actually engage in the process or act upon the information they receive. This article addresses this by exploring how participants in a particular trial (‘Get Moving’) experienced the process and nature of feedback. Although the trial aimed to compare the potential efficacy of three different monitoring activities designed to encourage greater physical activity, participants did not present distinctly different accounts of each intervention and the specifics of the feedback provided. Instead, their accounts took the form of much more extended and personal narratives that included other people and features of the environment. We draw on these broader descriptions to problematise the notion of self-monitoring and conclude that self-monitoring is neither solely about ‘self’ nor is it exclusively about ‘monitoring’. We suggest that a more expansive social and material understanding of feedback can give insight into the ways information is made active and meaningful for individuals in their everyday contexts. PMID:26466601

Skylab

NASA Image and Video Library

1973-01-01

This Skylab-2 onboard photograph shows astronaut Charles "Pete" Conrad exercising on a stationary bicycle (ergometer) used for monitoring the metabolism of the astronauts. The ergometer was used to conduct both Vectorcardiogram experiment (M093) and Metabolic Activity experiment (M171). Experiment M093 was a medical evaluation designed to monitor changes in astronauts' cardiovascular systems, while Experiment M171 was to measure astronauts' metabolic changes during long-duration space missions.

Media multitasking behavior: concurrent television and computer usage.

PubMed

Brasel, S Adam; Gips, James

2011-09-01

Changes in the media landscape have made simultaneous usage of the computer and television increasingly commonplace, but little research has explored how individuals navigate this media multitasking environment. Prior work suggests that self-insight may be limited in media consumption and multitasking environments, reinforcing a rising need for direct observational research. A laboratory experiment recorded both younger and older individuals as they used a computer and television concurrently, multitasking across television and Internet content. Results show that individuals are attending primarily to the computer during media multitasking. Although gazes last longer on the computer when compared to the television, the overall distribution of gazes is strongly skewed toward very short gazes only a few seconds in duration. People switched between media at an extreme rate, averaging more than 4 switches per min and 120 switches over the 27.5-minute study exposure. Participants had little insight into their switching activity and recalled their switching behavior at an average of only 12 percent of their actual switching rate revealed in the objective data. Younger individuals switched more often than older individuals, but other individual differences such as stated multitasking preference and polychronicity had little effect on switching patterns or gaze duration. This overall pattern of results highlights the importance of exploring new media environments, such as the current drive toward media multitasking, and reinforces that self-monitoring, post hoc surveying, and lay theory may offer only limited insight into how individuals interact with media.

Media Multitasking Behavior: Concurrent Television and Computer Usage

PubMed Central

Gips, James

2011-01-01

Abstract Changes in the media landscape have made simultaneous usage of the computer and television increasingly commonplace, but little research has explored how individuals navigate this media multitasking environment. Prior work suggests that self-insight may be limited in media consumption and multitasking environments, reinforcing a rising need for direct observational research. A laboratory experiment recorded both younger and older individuals as they used a computer and television concurrently, multitasking across television and Internet content. Results show that individuals are attending primarily to the computer during media multitasking. Although gazes last longer on the computer when compared to the television, the overall distribution of gazes is strongly skewed toward very short gazes only a few seconds in duration. People switched between media at an extreme rate, averaging more than 4 switches per min and 120 switches over the 27.5-minute study exposure. Participants had little insight into their switching activity and recalled their switching behavior at an average of only 12 percent of their actual switching rate revealed in the objective data. Younger individuals switched more often than older individuals, but other individual differences such as stated multitasking preference and polychronicity had little effect on switching patterns or gaze duration. This overall pattern of results highlights the importance of exploring new media environments, such as the current drive toward media multitasking, and reinforces that self-monitoring, post hoc surveying, and lay theory may offer only limited insight into how individuals interact with media. PMID:21381969

Non-destructive evaluation of laboratory scale hydraulic fracturing using acoustic emission

NASA Astrophysics Data System (ADS)

Hampton, Jesse Clay

The primary objective of this research is to develop techniques to characterize hydraulic fractures and fracturing processes using acoustic emission monitoring based on laboratory scale hydraulic fracturing experiments. Individual microcrack AE source characterization is performed to understand the failure mechanisms associated with small failures along pre-existing discontinuities and grain boundaries. Individual microcrack analysis methods include moment tensor inversion techniques to elucidate the mode of failure, crack slip and crack normal direction vectors, and relative volumetric deformation of an individual microcrack. Differentiation between individual microcrack analysis and AE cloud based techniques is studied in efforts to refine discrete fracture network (DFN) creation and regional damage quantification of densely fractured media. Regional damage estimations from combinations of individual microcrack analyses and AE cloud density plotting are used to investigate the usefulness of weighting cloud based AE analysis techniques with microcrack source data. Two granite types were used in several sample configurations including multi-block systems. Laboratory hydraulic fracturing was performed with sample sizes ranging from 15 x 15 x 25 cm3 to 30 x 30 x 25 cm 3 in both unconfined and true-triaxially confined stress states using different types of materials. Hydraulic fracture testing in rock block systems containing a large natural fracture was investigated in terms of AE response throughout fracture interactions. Investigations of differing scale analyses showed the usefulness of individual microcrack characterization as well as DFN and cloud based techniques. Individual microcrack characterization weighting cloud based techniques correlated well with post-test damage evaluations.

Time-Lapse Monitoring of an Engineering Scaled Excavation at Federal District, Brazil by Passive Ambient NoiseInterferometry

NASA Astrophysics Data System (ADS)

Cárdenas-Soto, M., Sr.; Hussain, Y.; Martinez-Carvajal, H., Sr.; Martino, S., Sr.; Rocha, M., Sr.

2016-12-01

Understanding the dynamics of stress relief mechanisms that lead to complete material collapse of unstable slopes is challenging. This research is focused on the novel use of Passive Ambient Noise Interferometry (PANI), a new technique that has revolutionized the seismology. In this technique the impulse response or Green function between two sensors is calculated by cross-correlation of the noise rescored at these stations. We applied PANI to monitor the deformational behavior of a prototype field experiment under semi controlled conditions for their use in landsliding early warning systems.The experimental setup consists of a 2 m engineering-scaled excavation,where induced failure was monitored by ambient vibrations propagating in tropical clayey deposits. The experimental setup consisted of dense network of 20 three components short period seismometers (Sercel L4C-3D) installed in three circular arrays with their distances from face of normal slope as 10, 20 and 30 meters, respectively.The frequency response of these seismometers is in range of 2-100 Hz. Recording was done in continuous mode at sampling rate of 1000 Hz with datalogger (RefTek DAS-130/3). Sensors were time synchronized by twenty 130 GPS/01. In this stage, the stress was applied on the one flank of this normal slope dug in the experimental field of University of Brasilia, by a hydraulic jack through a metallic plate. This incremental loading was kept on rising until the slope failure took place. This loading mechanism provided an opportunity to monitoring the changes in Rayleigh wave velocity before, during and after the complete failure. After initial processing, the green function (GF) or impulse response was calculated between each pair of sensors by cross correlation at time step of 4 second. All individual GFs, for entire monitoring period (30 minutes) were stacked to obtained a single reference GF. Stretching (dt/t) in waveform is calculated by subtracting individual GF from average GF, that gave Rayleigh wave velocity changes (dv/v=-dt/t). These changes correlated well with initiation and propagation of fracture at the face of this normal slope. It is concluded that cost effective technique, PANI has a good potential for the monitoring of time lapse changes of evolving fractures.

40 CFR 63.1086 - How must I monitor for leaks to cooling water?

Code of Federal Regulations, 2010 CFR

2010-07-01

... monitor for leaks to cooling water? You must monitor for leaks to cooling water by monitoring each heat... system so that the cooling water flow rate is 51,031 liters per minute or less so that a leak of 3.06 kg... detected a leak. (b) Individual heat exchangers. Monitor the cooling water at the entrance and exit of each...

Estimating wind-turbine-caused bird and bat fatality when zero carcasses are observed.

PubMed

Huso, Manuela M P; Dalthorp, Dan; Dail, David; Madsen, Lisa

2015-07-01

Many wind-power facilities in the United States have established effective monitoring programs to determine turbine-caused fatality rates of birds and bats, but estimating the number of fatalities of rare species poses special difficulties. The loss of even small numbers of individuals may adversely affect fragile populations, but typically, few (if any) carcasses are observed during monitoring. If monitoring design results in only a small proportion of carcasses detected, then finding zero carcasses may give little assurance that the number of actual fatalities is small. Fatality monitoring at wind-power facilities commonly involves conducting experiments to estimate the probability (g) an individual will be observed, accounting for the possibilities that it falls in an unsearched area, is scavenged prior to detection, or remains undetected even when present. When g < 1, the total carcass count (X) underestimates the total number of fatalities (M). Total counts can be 0 when M is small or when M is large and g < 1. Distinguishing these two cases is critical when estimating fatality of a rare species. Observing no individuals during searches may erroneously be interpreted as evidence of absence. We present an approach that uses Bayes' theorem to construct a posterior distribution for M, i.e., P(M \\ X, ĝ), reflecting the observed carcass count and previously estimated g. From this distribution, we calculate two values important to conservation: the probability that M is below a predetermined limit and the upper bound (M*) of the 100(1 - α)% credible interval for M. We investigate the dependence of M* on α, g, and the prior distribution of M, asking what value of g is required to attain a desired M for a given α. We found that when g < -0.15, M* was clearly influenced by the mean and variance of ĝ and the choice of prior distribution for M, but the influence of these factors is minimal when g > -0.45. Further, we develop extensions for temporal replication that can inform prior distributions of M and methods for combining information across several areas or time periods. We apply the method to data collected at a wind-power facility where scheduled searches yielded X = 0 raptor carcasses.

VA's expansion of supportive housing: successes and challenges on the path toward Housing First.

PubMed

Austin, Erika Laine; Pollio, David E; Holmes, Sally; Schumacher, Joseph; White, Bert; Lukas, Carol Vandeusen; Kertesz, Stefan

2014-05-01

The U.S. Department of Veterans Affairs (VA) is transitioning to a Housing First approach to placement of veterans in permanent supportive housing through the use of rental vouchers, an ambitious organizational transformation. This qualitative study examined the experiences of eight VA facilities undertaking this endeavor in 2012. A multidisciplinary team interviewed facility leadership, midlevel managers, and frontline staff (N=95 individuals) at eight VA facilities representing four U.S. regions. The team used a semistructured interview protocol and the constant comparative method to explore how individuals throughout the organizations experienced and responded to the challenges of transitioning to a Housing First approach. Frontline staff faced challenges in rapidly housing homeless veterans because of difficult rental markets, the need to coordinate with local public housing authorities, and a lack of available funds for move-in costs. Staff sought to balance their time spent on housing activities with intensive case management of highly vulnerable veterans. Finding low-demand sheltering options (that is, no expectations regarding sobriety or treatment participation, as in the Housing First model) for veterans waiting for housing presented a significant challenge to implementation of Housing First. Facility leadership supported Housing First implementation through resource allocation, performance monitoring, and reliance on midlevel managers to understand and meet the challenges of implementation. The findings highlight the considerable practical challenges and innovative solutions arising from a large-scale effort to implement Housing First, with particular attention to the experiences of individuals at all levels within an organization.

A purity monitor for the KEDR liquid krypton calorimeter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evtushenko, P. N.; Kotov, K. Yu.; Maslennikov, A. L.

We present a purity monitor for the KEDR liquid krypton calorimeter. A new method is suggested based on the usage of a short pulse of a gas discharge as a source of ultraviolet radiation for the photoproduction of electrons in a drift cell of the monitor. This paper describes the design of the monitor, the results of experiments with gaseous and liquid krypton, as well as the experience of using the developed device in the process of krypton purification for the KEDR liquid krypton calorimeter.

10 CFR 835.801 - Reports to individuals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... individuals. (a) Radiation exposure data for individuals monitored in accordance with § 835.402 shall be reported as specified in this section. The information shall include the data required under § 835.702(c... of the individual, and the individual's social security number, employee number, or other unique...

Why count trees? Volunteer motivations and experiences with tree monitoring in New York City

Treesearch

Michelle L. Johnson; Lindsay K. Campbell; Erika S. Svendsen; Philip Silva

2018-01-01

Volunteer programs can benefit from a deeper understanding of the motivations and experiences of people engaged in citizen science. Research to date has studied motivations of citizen scientists and tree-planting volunteers. Less work has focused on tree-monitoring volunteers, a role that is rapidly increasing as more cities involve the public in monitoring the urban...

Functionality of empirical model-based predictive analytics for the early detection of hemodynamic instabilty.

PubMed

Summers, Richard L; Pipke, Matt; Wegerich, Stephan; Conkright, Gary; Isom, Kristen C

2014-01-01

Background. Monitoring cardiovascular hemodynamics in the modern clinical setting is a major challenge. Increasing amounts of physiologic data must be analyzed and interpreted in the context of the individual patient’s pathology and inherent biologic variability. Certain data-driven analytical methods are currently being explored for smart monitoring of data streams from patients as a first tier automated detection system for clinical deterioration. As a prelude to human clinical trials, an empirical multivariate machine learning method called Similarity-Based Modeling (“SBM”), was tested in an In Silico experiment using data generated with the aid of a detailed computer simulator of human physiology (Quantitative Circulatory Physiology or “QCP”) which contains complex control systems with realistic integrated feedback loops. Methods. SBM is a kernel-based, multivariate machine learning method that that uses monitored clinical information to generate an empirical model of a patient’s physiologic state. This platform allows for the use of predictive analytic techniques to identify early changes in a patient’s condition that are indicative of a state of deterioration or instability. The integrity of the technique was tested through an In Silico experiment using QCP in which the output of computer simulations of a slowly evolving cardiac tamponade resulted in progressive state of cardiovascular decompensation. Simulator outputs for the variables under consideration were generated at a 2-min data rate (0.083Hz) with the tamponade introduced at a point 420 minutes into the simulation sequence. The functionality of the SBM predictive analytics methodology to identify clinical deterioration was compared to the thresholds used by conventional monitoring methods. Results. The SBM modeling method was found to closely track the normal physiologic variation as simulated by QCP. With the slow development of the tamponade, the SBM model are seen to disagree while the simulated biosignals in the early stages of physiologic deterioration and while the variables are still within normal ranges. Thus, the SBM system was found to identify pathophysiologic conditions in a timeframe that would not have been detected in a usual clinical monitoring scenario. Conclusion. In this study the functionality of a multivariate machine learning predictive methodology that that incorporates commonly monitored clinical information was tested using a computer model of human physiology. SBM and predictive analytics were able to differentiate a state of decompensation while the monitored variables were still within normal clinical ranges. This finding suggests that the SBM could provide for early identification of a clinical deterioration using predictive analytic techniques. predictive analytics, hemodynamic, monitoring.

Collection of Oral Fluids Using Cotton Ropes as a Sampling Method to Detect Foot-and-Mouth Disease Virus Infection in Pigs.

PubMed

Vosloo, W; Morris, J; Davis, A; Giles, M; Wang, J; Nguyen, H T T; Kim, P V; Quach, N V; Le, P T T; Nguyen, P H N; Dang, H; Tran, H X; Vu, P P; Hung, V V; Le, Q T; Tran, T M; Mai, T M T; Le, Q T V; Singanallur, N B

2015-10-01

In high-density farming practices, it is important to constantly monitor for infectious diseases, especially diseases that have the potential to spread rapidly between holdings. Pigs are known to amplify foot-and-mouth disease (FMD) by excreting large amounts of virus, and it is therefore important to detect the virus quickly and accurately to minimize the spread of disease. Ropes were used to collect oral fluid samples from pigs, and each sample was compared to saliva samples collected from individual animals by detecting FMD virus RNA using real-time PCR. Two different experiments are described where groups of pigs were infected with different serotypes of FMD virus, either with or without vaccination, and unvaccinated pigs were kept in aerosol contact. The sensitivity of the rope sampling varied between 0.67 and 0.92, and the statistical agreement between this method and individual sampling ranged from substantial to moderate for the two different serotypes. The ease of collecting oral fluids using ropes together with the high sensitivity of subsequent FMD detection through PCR indicates that this could be a useful method to monitor pig populations for FMD virus infection. With further validation of the sensitivity of detection of FMD virus RNA, this can be a cost-effective, non-invasive diagnostic tool. © 2013 Blackwell Verlag GmbH.

R & D of a Gas-Filled RF Beam Profile Monitor for Intense Neutrino Beam Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yonehara, K.; Backfish, M.; Moretti, A.

We report the R&D of a novel radiation-robust hadron beam profile monitor based on a gas-filled RF cavity for intense neutrino beam experiments. An equivalent RF circuit model was made and simulated to optimize the RF parameter in a wide beam intensity range. As a result, the maximum acceptable beam intensity in the monitor is significantly increased by using a low-quality factor RF cavity. The plan for the demonstration test is set up to prepare for future neutrino beam experiments.

OpenKnowledge for peer-to-peer experimentation in protein identification by MS/MS

PubMed Central

2011-01-01

Background Traditional scientific workflow platforms usually run individual experiments with little evaluation and analysis of performance as required by automated experimentation in which scientists are being allowed to access numerous applicable workflows rather than being committed to a single one. Experimental protocols and data under a peer-to-peer environment could potentially be shared freely without any single point of authority to dictate how experiments should be run. In such environment it is necessary to have mechanisms by which each individual scientist (peer) can assess, locally, how he or she wants to be involved with others in experiments. This study aims to implement and demonstrate simple peer ranking under the OpenKnowledge peer-to-peer infrastructure by both simulated and real-world bioinformatics experiments involving multi-agent interactions. Methods A simulated experiment environment with a peer ranking capability was specified by the Lightweight Coordination Calculus (LCC) and automatically executed under the OpenKnowledge infrastructure. The peers such as MS/MS protein identification services (including web-enabled and independent programs) were made accessible as OpenKnowledge Components (OKCs) for automated execution as peers in the experiments. The performance of the peers in these automated experiments was monitored and evaluated by simple peer ranking algorithms. Results Peer ranking experiments with simulated peers exhibited characteristic behaviours, e.g., power law effect (a few dominant peers dominate), similar to that observed in the traditional Web. Real-world experiments were run using an interaction model in LCC involving two different types of MS/MS protein identification peers, viz., peptide fragment fingerprinting (PFF) and de novo sequencing with another peer ranking algorithm simply based on counting the successful and failed runs. This study demonstrated a novel integration and useful evaluation of specific proteomic peers and found MASCOT to be a dominant peer as judged by peer ranking. Conclusion The simulated and real-world experiments in the present study demonstrated that the OpenKnowledge infrastructure with peer ranking capability can serve as an evaluative environment for automated experimentation. PMID:22192521

Viability of modelling gas transport in shallow injection-monitoring experiment field at Maguelone, France

NASA Astrophysics Data System (ADS)

Basirat, Farzad; Perroud, Hervé; Lofi, Johanna; Denchik, Nataliya; Lods, Gérard; Fagerlund, Fritjof; Sharma, Prabhakar; Pezard, Philippe; Niemi, Auli

2015-04-01

In this study, TOUGH2/EOS7CA model is used to simulate the shallow injection-monitoring experiment carried out at Maguelone, France, during 2012 and 2013. The possibility of CO2 leakage from storage reservoir to upper layers is one of the issues that need to be addressed in CCS projects. Developing reliable monitoring techniques to detect and characterize CO2 leakage is necessary for the safety of CO2 storage in reservoir formations. To test and cross-validate different monitoring techniques, a series of shallow gas injection-monitoring experiments (SIMEx) has been carried out at the Maguelone. The experimental site is documented in Lofi et al [2013]. At the site, a series of nitrogen and one CO2 injection experiment have been carried out during 2012-2013 and different monitoring techniques have been applied. The purpose of modelling is to acquire understanding of the system performance as well as to further develop and validate modelling approaches for gas transport in the shallow subsurface, against the well-controlled data sets. The preliminary simulation of the experiment including the simulation for the Nitrogen injection test in 2012 was presented in Basirat et al [2013]. In this work, the simulations represent the gaseous CO2 distribution and dissolved CO2 within range obtained by monitoring approaches. The Multiphase modelling in combination with geophysical monitoring can be used for process understanding of gas phase migration- and mass transfer processes resulting from gaseous CO2 injection. Basirat, F., A. Niemi, H. Perroud, J. Lofi, N. Denchik, G. Lods, P. Pezard, P. Sharma, and F. Fagerlund (2013), Modeling Gas Transport in the Shallow Subsurface in Maguelone Field Experiment, Energy Procedia, 40, 337-345. Lofi, J., P. Pezard, F. Bouchette, O. Raynal, P. Sabatier, N. Denchik, A. Levannier, L. Dezileau, and R. Certain (2013), Integrated Onshore-Offshore Investigation of a Mediterranean Layered Coastal Aquifer, Groundwater, 51(4), 550-561.

CHARACTERIZATION OF SMALL ESTUARIES AS A COMPONENT OF A REGIONAL-SCALE MONITORING PROGRAM

EPA Science Inventory

Large-scale environmental monitoring programs, such as EPA's Environmental Monitoring and Assessment Program (EMAP), by nature focus on estimating the ecological condition of large geographic areas. Generally missing is the ability to provide estimates of condition of individual ...

Perceived parental monitoring and adolescent internet addiction: A moderated mediation model.

PubMed

Ding, Qingwen; Li, Dongping; Zhou, Yueyue; Dong, Hongning; Luo, Jinjing

2017-11-01

Bronfenbrenner's (1979) ecological model focuses on the interrelation between different contexts and the interaction between individuals and their proximal contexts. Based on this theory, the present study tested a moderated mediation model of family, peer, and individual characteristics to investigate how they impact adolescent Internet addiction. Specifically, we examined whether deviant peer affiliation partially mediated the relation between perceived parental monitoring and adolescent Internet addiction, and whether this indirect relation was moderated by effortful control. A total of 747 Chinese middle school students filled out anonymous questionnaires concerning perceived parental monitoring, deviant peer affiliation, effortful control, and Internet addiction. The findings indicated that while the impact of parental monitoring on Internet addiction was partially mediated by deviant peer affiliation, effortful control moderated the first stage of the indirect relationship. For low effortful control adolescents, perceived parental monitoring negatively predicted deviant peer affiliation. Conversely, the indirect path was not significant for high effortful control adolescents. These findings highlight the need to consider family, peer and individual factors simultaneously when evaluating risks associated with adolescent Internet addiction and have important implications for the prevention and intervention of adolescent Internet addiction. Copyright © 2017 Elsevier Ltd. All rights reserved.

Detecting Vital Signs with Wearable Wireless Sensors

PubMed Central

Yilmaz, Tuba; Foster, Robert; Hao, Yang

2010-01-01

The emergence of wireless technologies and advancements in on-body sensor design can enable change in the conventional health-care system, replacing it with wearable health-care systems, centred on the individual. Wearable monitoring systems can provide continuous physiological data, as well as better information regarding the general health of individuals. Thus, such vital-sign monitoring systems will reduce health-care costs by disease prevention and enhance the quality of life with disease management. In this paper, recent progress in non-invasive monitoring technologies for chronic disease management is reviewed. In particular, devices and techniques for monitoring blood pressure, blood glucose levels, cardiac activity and respiratory activity are discussed; in addition, on-body propagation issues for multiple sensors are presented. PMID:22163501

Accommodative and convergence response to computer screen and printed text

NASA Astrophysics Data System (ADS)

Ferreira, Andreia; Lira, Madalena; Franco, Sandra

2011-05-01

The aim of this work was to find out if differences exist in accommodative and convergence response for different computer monitors' and a printed text. It was also tried to relate the horizontal heterophoria value and accommodative response with the symptoms associated with computer use. Two independents experiments were carried out in this study. The first experiment was measuring the accommodative response on 89 subjects using the Grand Seiko WAM-5500 (Grand Seiko Co., Ltd., Japan). The accommodative response was measured using three computer monitors: a 17-inch cathode ray tube (CRT), two liquid crystal displays LCDs, one 17-inch (LCD17) and one 15 inches (LCD15) and a printed text. The text displayed was always the same for all the subjects and tests. A second experiment aimed to measure the value of habitual horizontal heterophoria on 80 subjects using the Von Graefe technique. The measurements were obtained using the same target presented on two different computer monitors, one 19-inch cathode ray tube (CRT) and other 19 inches liquid crystal displays (LCD) and printed on paper. A small survey about the incidence and prevalence of symptoms was performed similarly in both experiments. In the first experiment, the accommodation response was higher in the CRT and LCD's than for paper. There were not found significantly different response for both LCD monitors'. The second experiment showed that, the heterophoria values were similar for all the stimuli. On average, participants presented a small exophoria. In both experiments, asthenopia was the symptom that presented higher incidence. There are different accommodative responses when reading on paper or on computer monitors. This difference is more significant for CRT monitors. On the other hand, there was no difference in the values of convergence for the computer monitors' and paper. The symptoms associated with the use of computers are not related with the increase in accommodation and with the horizontal heterophoria values.

The Use of Individual Growth and Developmental Indicators for Progress Monitoring and Intervention Decision Making in Early Education

ERIC Educational Resources Information Center

Walker, Dale; Carta, Judith J.; Greenwood, Charles R.; Buzhardt, Joseph F.

2008-01-01

Progress monitoring tools have been shown to be essential elements in current approaches to intervention problem-solving models. Such tools have been valuable not only in marking individual children's level of performance relative to peers but also in measuring change in skill level in a way that can be attributed to intervention and development.…

The Role of Self-Monitoring in Assessing Individual Students' Quantity and Quality of Comments in Large-Class Discussion

ERIC Educational Resources Information Center

Carstens, B. A.; Wright, J. M.; Coles, J. T.; McCleary, L. N.; Williams, R. L.

2013-01-01

This study developed a reliable and valid self-monitoring procedure for student use in recording and rating the quality of their individual comments in large college classes. Students used daily record cards immediately to record and rate each comment they made each day. However, a limit was set on the amount of credit students could claim for…

Towards the establishment of landbird migration monitoring networks in the United States

Treesearch

Jay D. Carlisle; C. John Ralph

2005-01-01

Migration monitoring of landbirds, in its various forms, is a well-established research endeavor across much of North America. While monitoring efforts at individual sites have contributed much to our knowledge of the biology of migrants, these studies have limited potential for population monitoring and for addressing certain broader questions about migrants....

Mechanisms of mindfulness training: Monitor and Acceptance Theory (MAT).

PubMed

Lindsay, Emily K; Creswell, J David

2017-02-01

Despite evidence linking trait mindfulness and mindfulness training with a broad range of effects, still little is known about its underlying active mechanisms. Mindfulness is commonly defined as (1) the ongoing monitoring of present-moment experience (2) with an orientation of acceptance. Building on conceptual, clinical, and empirical work, we describe a testable theoretical account to help explain mindfulness effects on cognition, affect, stress, and health outcomes. Specifically, Monitor and Acceptance Theory (MAT) posits that (1), by enhancing awareness of one's experiences, the skill of attention monitoring explains how mindfulness improves cognitive functioning outcomes, yet this same skill can increase affective reactivity. Second (2), by modifying one's relation to monitored experience, acceptance is necessary for reducing affective reactivity, such that attention monitoring and acceptance skills together explain how mindfulness improves negative affectivity, stress, and stress-related health outcomes. We discuss how MAT contributes to mindfulness science, suggest plausible alternatives to the account, and offer specific predictions for future research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mechanisms of Mindfulness Training: Monitor and Acceptance Theory (MAT)1

PubMed Central

Lindsay, Emily K.; Creswell, J. David

2016-01-01

Despite evidence linking trait mindfulness and mindfulness training with a broad range of effects, still little is known about its underlying active mechanisms. Mindfulness is commonly defined as (1) the ongoing monitoring of present-moment experience (2) with an orientation of acceptance. Building on conceptual, clinical, and empirical work, we describe a testable theoretical account to help explain mindfulness effects on cognition, affect, stress, and health outcomes. Specifically, Monitor and Acceptance Theory (MAT) posits that (1), by enhancing awareness of one’s experiences, the skill of attention monitoring explains how mindfulness improves cognitive functioning outcomes, yet this same skill can increase affective reactivity. Second (2), by modifying one’s relation to monitored experience, acceptance is necessary for reducing affective reactivity, such that attention monitoring and acceptance skills together explain how mindfulness improves negative affectivity, stress, and stress-related health outcomes. We discuss how MAT contributes to mindfulness science, suggest plausible alternatives to the account, and offer specific predictions for future research. PMID:27835764

Stability of monitoring weak changes in multiply scattering media with ambient noise correlation: laboratory experiments.

PubMed

Hadziioannou, Céline; Larose, Eric; Coutant, Olivier; Roux, Philippe; Campillo, Michel

2009-06-01

Previous studies have shown that small changes can be monitored in a scattering medium by observing phase shifts in the coda. Passive monitoring of weak changes through ambient noise correlation has already been applied to seismology, acoustics, and engineering. Usually, this is done under the assumption that a properly reconstructed Green function (GF), as well as stable background noise sources, is necessary. In order to further develop this monitoring technique, a laboratory experiment was performed in the 2.5 MHz range in a gel with scattering inclusions, comparing an active (pulse-echo) form of monitoring to a passive (correlation) one. Present results show that temperature changes in the medium can be observed even if the GF of the medium is not reconstructed. Moreover, this article establishes that the GF reconstruction in the correlations is not a necessary condition: The only condition to monitoring with correlation (passive experiment) is the relative stability of the background noise structure.

Enhancements and Evolution of the Real Time Mission Monitor

NASA Technical Reports Server (NTRS)

Goodman, Michael; Blakeslee, Richard; Hardin, Danny; Hall, John; He, Yubin; Regner, Kathryn

2008-01-01

The Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the National Aeronautics and Space Administration (NASA) Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery, radar, surface and airborne instrument data sets, model output parameters, lightning location observations, aircraft navigation data, soundings, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual globe application. RTMM has proven extremely valuable for optimizing individual Earth science airborne field experiments. Flight planners, mission scientists, instrument scientists and program managers alike appreciate the contributions that RTMM makes to their flight projects. We have received numerous plaudits from a wide variety of scientists who used RTMM during recent field campaigns including the 2006 NASA African Monsoon Multidisciplinary Analyses (NAMMA), 2007 Tropical Composition, Cloud, and Climate Coupling (TC4), 2008 Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) missions, the 2007-2008 NOAA-NASA Aerosonde Hurricane flights and the 2008 Soil Moisture Active-Passive Validation Experiment (SMAP-VEX). Improving and evolving RTMM is a continuous process. RTMM recently integrated the Waypoint Planning Tool, a Java-based application that enables aircraft mission scientists to easily develop a pre-mission flight plan through an interactive point-and-click interface. Individual flight legs are automatically calculated for altitude, latitude, longitude, flight leg distance, cumulative distance, flight leg time, cumulative time, and satellite overpass intersections. The resultant flight plan is then generated in KML and quickly posted to the Google Earth-based RTMM for interested scientists to view the planned flight track and then compare it to the actual real time flight progress. A description of the system architecture, components, and applications along with reviews and animations of RTMM during the field campaigns, plus planned enhancements and future opportunities will be presented.

Enhancements and Evolution of the Real Time Mission Monitor

NASA Astrophysics Data System (ADS)

Goodman, M.; Blakeslee, R.; Hardin, D.; Hall, J.; He, Y.; Regner, K.

2008-12-01

The Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the National Aeronautics and Space Administration (NASA) Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery, radar, surface and airborne instrument data sets, model output parameters, lightning location observations, aircraft navigation data, soundings, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual earth application. RTMM has proven extremely valuable for optimizing individual Earth science airborne field experiments. Flight planners, mission scientists, instrument scientists and program managers alike appreciate the contributions that RTMM makes to their flight projects. RTMM has received numerous plaudits from a wide variety of scientists who used RTMM during recent field campaigns including the 2006 NASA African Monsoon Multidisciplinary Analyses (NAMMA), 2007 Tropical Composition, Cloud, and Climate Coupling (TC4), 2008 Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) missions, the 2007-2008 NOAA-NASA Aerosonde Hurricane flights and the 2008 Soil Moisture Active-Passive Validation Experiment (SMAP-VEX). Improving and evolving RTMM is a continuous process. RTMM recently integrated the Waypoint Planning Tool, a Java-based application that enables aircraft mission scientists to easily develop a pre-mission flight plan through an interactive point-and-click interface. Individual flight legs are automatically calculated for altitude, latitude, longitude, flight leg distance, cumulative distance, flight leg time, cumulative time, and satellite overpass intersections. The resultant flight plan is then generated in KML and quickly posted to the Google Earth-based RTMM for planning discussions, as well as comparisons to real time flight tracks in progress. A description of the system architecture, components, and applications along with reviews and animations of RTMM during the field campaigns, plus planned enhancements and future opportunities will be presented.

How do working-memory-related demand, reasoning ability and aversive reinforcement modulate conflict monitoring?

PubMed Central

Leue, Anja; Weber, Bernd; Beauducel, André

2014-01-01

Conflict monitoring is a process of stimulus evaluation and a pre-requisite for subsequent recruitment of cognitive control and behavioral adaptations. This study investigated how experimentally manipulated working-memory-related cognitive demand and aversive reinforcement modulate individual differences of conflict monitoring intensity and behavioral adjustments. Individual differences were assessed by means of an anxiety-related trait dimension (trait-BIS) and by means of reasoning abilities—a core determinant of intelligence. Moreover, we investigated the special role of verbal reasoning ability and figural reasoning ability for the modulation of the conflict monitoring intensity. Ninety participants performed a go/nogo task with four conditions each comprising a combination of low vs. high working-memory-related cognitive demand and low vs. high aversive reinforcement. No effect of aversive reinforcement was observed for the N2 amplitude. The fronto-central nogo N2 amplitude was more pronounced for high demand vs. low demand suggesting that cognitive demand served as an aversive costly event. Higher total reasoning abilities were associated with more intense conflict monitoring and shorter response times with increasing aversive reinforcement (defined as verbal error-feedback vs. monetary loss). Individuals with higher trait-BIS scores demonstrated a more intense conflict monitoring even in conditions with low aversive reinforcement and also a more cautious responding (i.e., response times slowing) with increasing aversive reinforcement indicating a focus on negative feedback prevention. The findings provide evidence for the conflict monitoring theory and suggest that working-memory-related demand overrules the impact of aversive reinforcement on conflict monitoring intensity. Reasoning abilities and anxiety-related traits go along with an intensification of conflict monitoring but differences in the flexibility of behavioral adjustment. PMID:24782739

Skylab

NASA Image and Video Library

1970-01-01

This 1970 photograph shows equipment for the Skylab's Sleep Monitoring Experiment (M133), a medical evaluation designed to objectively determine the amount and quality of crewmembers' inflight sleep. The experiment monitored and recorded electroencephalographic (EEG) and electrooculographic (EOG) activity during astronauts' sleep periods. One of the astronauts was selected for this experiment and wore a fitted cap during his sleep periods. The Marshall Space Flight Center had program management responsibility for the development of Skylab hardware and experiments.

Telemetric intra-cranial pressure monitoring: clinical and financial considerations.

PubMed

Barber, James M; Pringle, Catherine J; Raffalli-Ebezant, Helen; Pathmanaban, Omar; Ramirez, Roberto; Kamaly-Asl, Ian D

2017-06-01

Intracranial pressure (ICP) measurement is an important diagnostic tool in Neurosurgery. Until relatively recently, conventional monitoring has required that subjects be admitted to a hospital bed and the device is only able to be left in-situ for limited periods of time. We have evaluated a Telemetric ICP monitoring system that has been proven, by several other groups worldwide, to permit rapid, repeated and prolonged ICP measurement, in multiple environments. In our unit, 4 patients have been implanted to-date, between the ages of 4 and 16, manifesting a wide range of complex neurosurgical conditions. The sensors have been left in-situ for between 460 and 632 days. There have been no clinical complications and the system has been universally well tolerated. Clinical events, costs and patient experience were all assessed prior to and following implantation. Overall, there was a significant reduction in associated admissions (44.3%), imaging requirements (72.5%) and costs (50.0%). Subjective feedback from both the patients (where possible) and their families was overwhelmingly positive, partly due to (a) the system's ease of use, (b) its ability to reduce the number of admissions/tests required and (c) the facility for rapid measurement of ICP that permitted on-the-spot reassurance of concerns. Additionally, the ability to monitor ICP at home and/or whilst ambulant, has provided measurements that were hitherto inaccessible to our team, facilitating all the potential benefits that analysis of such information would provide. Indeed, we have seen the resultant management in each case has been completely altered by the availability of this data, reaffirming that the importance of being able to obtain it should not be underestimated. The combination of both this and the ability to markedly improve patient experience, along with generating significant cost-savings, lead the authors to suggest that the implantation of this system should be strongly considered in selected individuals.

Mobile-Based Nutrition and Child Health Monitoring to Inform Program Development: An Experience From Liberia.

PubMed

Guyon, Agnes; Bock, Ariella; Buback, Laura; Knittel, Barbara

2016-12-23

Implementing complex nutrition and other public health projects and tracking nutrition interventions, such as women's diet and supplementation and infant and young child feeding practices, requires reliable routine data to identify potential program gaps and to monitor trends in behaviors in real time. However, current monitoring and evaluation practices generally do not create an environment for this real-time tracking. This article describes the development and application of a mobile-based nutrition and health monitoring system, which collected monitoring data on project activities, women's nutrition, and infant and young child feeding practices in real time. The Liberia Agricultural Upgrading Nutrition and Child Health (LAUNCH) project implemented a nutrition and health monitoring system between April 2012 and June 2014. The LAUNCH project analyzed project monitoring and outcome data from the system and shared selected behavioral and programmatic indicators with program managers through a short report, which later evolved into a visual data dashboard, during program-update meetings. The project designed protocols to ensure representativeness of program participants. LAUNCH made programmatic adjustments in response to findings from the monitoring system; these changes were then reflected in subsequent quarterly trends, indicating that the availability of timely data allowed for the project to react quickly to issues and adapt the program appropriately. Such issues included lack of participation in community groups and insufficient numbers of food distribution points. Likewise, the system captured trends in key outcome indicators such as breastfeeding and complementary feeding practices, linking them to project activities and external factors including seasonal changes and national health campaigns. Digital data collection platforms can play a vital role in improving routine programmatic functions. Fixed gathering locations such as food distribution points represent an opportunity to easily access program participants and enable managers to identify strengths and weaknesses in project implementation. For programs that track individuals over time, a mobile tool combined with a strong database can greatly improve efficiency and data visibility and reduce resource leakages. © Guyon et al.

Suggesting a new framework for predictive performance assessment: Trait vs State dimensions.

NASA Astrophysics Data System (ADS)

Pattyn, Nathalie; Neyt, Xavier; Migeotte, Pierre-François; Morais, José; Soetens, Eric; Cluydts, Raymond; Meeusen, Romain; de Schutter, Guy; Nederhof, Esther; Kolinsky, Régine

IntroductionA major aim of performance investigation is to predict real-life performance, which is why both ESA (1) and NASA (2) have described the need to validly and reliably detect potential performance decrement as absolute requirements to manned long-duration missions. Whereas the predictive validity of such assessment has been extensively described for medium-term to long-term outcomes, as is the case for cognitive performance selection of student pilots for example, similar evidence is lacking regarding the immediate predictive value of cognitive testing, i.e., whether these results reflect real-life performance on an immediately subsequent task. Furthermore, whereas selection procedures are derived from population-based approaches, real-time monitoring of performance is often meant to be individual, which is an additional call for caution before concluding results from one setting to be applied to another. The MiniCog Rapid Assessment Battery (MRAB), which was termed by its authors "a blood pressure cuff for the mind" (3), aims at reflecting the functional status of a subject at any given moment. This battery was designed to provide a remote cognitive assessment of astronauts on a regular basis. We investigated its predictive value for real-life performance, together with a new approach to the assessment of cognitive performance in operational conditions, based on interference paradigms, the addition of emotionally loaded material and the concomitant measure of cardio-respiratory responses (4). MethodIn a first experiment, we investigated whether psychophysiological results would predict success of military student pilots (SPs; N=14) on a major evaluation flight right after the testing, and success in the rest of their flight training after a 6 months period. In a second experiment, we investigated whether extensive preliminary cognitive testing and individually tailored longitudinal monitoring of physical and cognitive performance could predict success of Special Forces trainees (N=7) during their training. ResultsThe first experiment showed no relationship whatsoever between cognitive performance on the very broad array of tests and immediately subsequent performance on the evaluation flight. However, physiological results showed a trend for students who passed the test to exhibit a larger physiological reactivity. Furthermore, the medium-term outcome of SPs in their flight training showed to be related to their test performance. Results of the second experiment (still in progress) will show whether, for an individual monitoring situation, there is a potential link between performance IQ and success on the training, and whether the longitudinal assessment of both cognitive performance, physical performance and physiological reactivity relates to immediately subsequent performance. DiscussionThese results suggest that a critical distinction could be made regarding predictive performance assessment, namely trait and state dimensions. Since one of the intended uses of operational test batteries is to provide an instantaneous measure of the cognitive status of the subject to allow the immediate execution of critical tasks, our results show this would be an inappropriate application so far. However, a dimension showing promising potential is the physiological reactivity. Whereas operational priorities clearly state the need for performance evaluation tools, their application cannot guide operational choices before sufficient validation allows justifying such decisions. References(1) HUMEX: Study on the Survivability and Adaptation of Humans to Long-duration Exploratory Missions (2000). European Space Agency. (2)BPCR: Bioastronautics Critical Path Roadmap (2004). National Aeronautics and Space Administration. (3) Shephard, J. M. and Kosslyn, S. M. (2005). The MiniCog rapid assessment battery: Developing a "blood pressure cuff for the mind". Avn Space Enl Medicine, 76, B192-B197. (4) Pattyn, N.; Migeotte, P.F.; Morais, J.; Soetens, E.; Cluydts, R. and Kolinsky, R. (2007). Crew performance monitoring: Putting some feeling into it. Proceedings of the 58th International Astronautical Congress, IAC-07-A1.1.04.

Feeling the digital pulse: Consumer-centered approach to individual health profiling.

PubMed

Wong, Thomas K S

2006-01-01

New technologies from the new digital era are overcoming temporal, spatial and physical hurdles in the development and realization of individual health profiling and consumer health monitoring devices. Mature wireless and networking technologies promise more accessibility and portability of health data and records, and health monitoring. The increase in convenience and efficiency underlie the technological foundation for development of telehealth systems, which make personal health care available anytime, anywhere. On the one hand, advances in information technology are aiding in the creation of lifelong health records and hence in the tracking and understanding of the health history of individuals, which in turn will help shift the public health care delivery model toward more primary and secondary care and prevention from the current emphasis on curing. On the other, health monitoring devices are also benefiting from technological progress, and are increasingly moving toward more self-assistive, compact and appealing to consumers. However, although most of the necessary hardware and technologies are already mature and widely available, they have yet to be fully exploited for personal health care, and the general public also need to be educated and encouraged to adopt the concepts of individual health profiling and regular health monitoring into their lives. In this regard, the School of Nursing at The Hong Kong Polytechnic University has been working proactively on two fronts. First, a telehealth system has been installed in community-based venues such as clinics, hospitals and, most important, schools and youth centers in order to promote lifelong health profiling for all individuals. Second, the School of Nursing is committed to utilizing advanced technologies for developing more compact and user-friendly consumer health monitoring devices such as non-invasive meters. This is with a view to encourage individuals to take more responsibility for their own health and behavior, which fits in with the Hong Kong government's aim of shifting the burden of public health care provision away from hospitals to community-based primary and secondary care. The ultimate goal of the School of Nursing's efforts in telehealth and consumer health monitoring devices is the wide adoption of home-based telehealth systems that will subsequently spur individual health profiling, which will in turn encourage personal responsibility for improving one's health.

Dietary cadmium and benzo(a)pyrene increased intestinal metallothionein expression in the fish Fundulus heteroclitus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roesijadi, Guritno; Rezvankhah, Saeid; Perez-Matus, Alejandro

2008-10-17

To test the effect of dietary exposure to cadmium and benzo(a)pyrene on induction of metallothionein mRNA in the Fundulus heteroclitus, fish were individually fed a pelletized gel food containing cadmium, benzo(a)pyrene, or a combination of the two over a period of seven days, then analyzed for relative levels of metallothionein mRNA in the intestine, liver, and gill using real-time RT-qPCR. An initial experiment with only cadmium exposure showed an apparent 10-fold induction in the intestine, but no induction in liver or gill. Ingestion of contaminated pellets varied in individual fish, and because it was possible to monitor individual ingestion ratesmore » with our method, individual cadmium doses were estimated from the amount of ingested cadmium. When the levels of metallothionein mRNA were related to the dose to each fish, a linear dose-response relationship was observed for the intestine, but not the other organs, which showed no induction. In a second experiment, dose was controlled by placing the entire daily cadmium dose into a single contaminated pellet that was fed first (thereby, effectively controlling the effect of variable ingestion rates), and the interaction between cadmium and benzo(a)pyrene was also investigated. The intestine was again the primary organ for metallothionein induction by cadmium, with a 20-fold increase in metallothionein mRNA over control levels. When benzo(a)pyrene was administered together with cadmium, induction of metallothionein was potentiated by the presence of benzo(a)pyrene, with the main effect seen in the intestine, where already high levels of induction by cadmium alone increased by 1.74-fold when benzo(a)pyrene was present.« less

Social Experience Is Sufficient to Modulate Sleep Need of Drosophila without Increasing Wakefulness.

PubMed

Lone, Shahnaz Rahman; Potdar, Sheetal; Srivastava, Manishi; Sharma, Vijay Kumar

2016-01-01

Organisms quickly learn about their surroundings and display synaptic plasticity which is thought to be critical for their survival. For example, fruit flies Drosophila melanogaster exposed to highly enriched social environment are found to show increased synaptic connections and a corresponding increase in sleep. Here we asked if social environment comprising a pair of same-sex individuals could enhance sleep in the participating individuals. To study this, we maintained individuals of D. melanogaster in same-sex pairs for a period of 1 to 4 days, and after separation, monitored sleep of the previously socialized and solitary individuals under similar conditions. Males maintained in pairs for 3 or more days were found to sleep significantly more during daytime and showed a tendency to fall asleep sooner as compared to solitary controls (both measures together are henceforth referred to as "sleep-enhancement"). This sleep phenotype is not strain-specific as it is observed in males from three different "wild type" strains of D. melanogaster. Previous studies on social interaction mediated sleep-enhancement presumed 'waking experience' during the interaction to be the primary underlying cause; however, we found sleep-enhancement to occur without any significant increase in wakefulness. Furthermore, while sleep-enhancement due to group-wise social interaction requires Pigment Dispersing Factor (PDF) positive neurons; PDF positive and CRYPTOCHROME (CRY) positive circadian clock neurons and the core circadian clock genes are not required for sleep-enhancement to occur when males interact in pairs. Pair-wise social interaction mediated sleep-enhancement requires dopamine and olfactory signaling, while visual and gustatory signaling systems seem to be dispensable. These results suggest that socialization alone (without any change in wakefulness) is sufficient to cause sleep-enhancement in fruit fly D. melanogaster males, and that its neuronal control is context-specific.

Carving Metacognition at Its Joints: Protracted Development of Component Processes

ERIC Educational Resources Information Center

O'Leary, Allison; Sloutsky, Vladimir

2017-01-01

Two experiments investigated the development of metacognitive monitoring and control, and conditions under which children engage these processes. In Experiment 1, 5-year-olds (N = 30) and 7-year-olds (N = 30), unlike adults (N = 30), showed little evidence of either monitoring or control. In Experiment 2, 5-year-olds (N = 90) were given…

System of Monitoring the Quality of Higher Education in UK Universities: Experience for Ukraine

ERIC Educational Resources Information Center

Krasilnikova, Hanna

2014-01-01

The article deals with the experience of the use of the system of internal monitoring of the quality of higher education in UK Universities. There has been analyzed the existing model of the system of higher education monitoring at the level of a higher education institution within the scope of the British higher education model, discovered by a…

Structure and Possible Functions of Constant-Frequency Calls in Ariopsis seemanni (Osteichthyes, Ariidae)

PubMed Central

Schmidtke, Daniel; Schulz, Jochen; Hartung, Jörg; Esser, Karl-Heinz

2013-01-01

In the 1970s, Tavolga conducted a series of experiments in which he found behavioral evidence that the vocalizations of the catfish species Ariopsis felis may play a role in a coarse form of echolocation. Based on his findings, he postulated a similar function for the calls of closely related catfish species. Here, we describe the physical characteristics of the predominant call-type of Ariopsis seemanni. In two behavioral experiments, we further explore whether A. seemanni uses these calls for acoustic obstacle detection by testing the hypothesis that the call-emission rate of individual fish should increase when subjects are confronted with novel objects, as it is known from other vertebrate species that use pulse-type signals to actively probe the environment. Audio-video monitoring of the fish under different obstacle conditions did not reveal a systematic increase in the number of emitted calls in the presence of novel objects or in dependence on the proximity between individual fish and different objects. These negative findings in combination with our current understanding of directional hearing in fishes (which is a prerequisite for acoustic obstacle detection) make it highly unlikely that A. seemanni uses its calls for acoustic obstacle detection. We argue that the calls are more likely to play a role in intra- or interspecific communication (e.g. in school formation or predator deterrence) and present results from a preliminary Y-maze experiment that are indicative for a positive phonotaxis of A. seemanni towards the calls of conspecifics. PMID:23741408

40 CFR 63.143 - Process wastewater provisions-inspections and monitoring of operations.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-inspections and monitoring of operations. 63.143 Section 63.143 Protection of Environment ENVIRONMENTAL..., and Wastewater § 63.143 Process wastewater provisions—inspections and monitoring of operations. (a) For each wastewater tank, surface impoundment, container, individual drain system, and oil-water...

40 CFR 63.143 - Process wastewater provisions-inspections and monitoring of operations.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-inspections and monitoring of operations. 63.143 Section 63.143 Protection of Environment ENVIRONMENTAL..., and Wastewater § 63.143 Process wastewater provisions—inspections and monitoring of operations. (a) For each wastewater tank, surface impoundment, container, individual drain system, and oil-water...

40 CFR 63.143 - Process wastewater provisions-inspections and monitoring of operations.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-inspections and monitoring of operations. 63.143 Section 63.143 Protection of Environment ENVIRONMENTAL..., and Wastewater § 63.143 Process wastewater provisions—inspections and monitoring of operations. (a) For each wastewater tank, surface impoundment, container, individual drain system, and oil-water...

40 CFR 63.143 - Process wastewater provisions-inspections and monitoring of operations.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-inspections and monitoring of operations. 63.143 Section 63.143 Protection of Environment ENVIRONMENTAL..., and Wastewater § 63.143 Process wastewater provisions—inspections and monitoring of operations. (a) For each wastewater tank, surface impoundment, container, individual drain system, and oil-water...

Predictive Monitoring for Improved Management of Glucose Levels

PubMed Central

Reifman, Jaques; Rajaraman, Srinivasan; Gribok, Andrei; Ward, W. Kenneth

2007-01-01

Background Recent developments and expected near-future improvements in continuous glucose monitoring (CGM) devices provide opportunities to couple them with mathematical forecasting models to produce predictive monitoring systems for early, proactive glycemia management of diabetes mellitus patients before glucose levels drift to undesirable levels. This article assesses the feasibility of data-driven models to serve as the forecasting engine of predictive monitoring systems. Methods We investigated the capabilities of data-driven autoregressive (AR) models to (1) capture the correlations in glucose time-series data, (2) make accurate predictions as a function of prediction horizon, and (3) be made portable from individual to individual without any need for model tuning. The investigation is performed by employing CGM data from nine type 1 diabetic subjects collected over a continuous 5-day period. Results With CGM data serving as the gold standard, AR model-based predictions of glucose levels assessed over nine subjects with Clarke error grid analysis indicated that, for a 30-minute prediction horizon, individually tuned models yield 97.6 to 100.0% of data in the clinically acceptable zones A and B, whereas cross-subject, portable models yield 95.8 to 99.7% of data in zones A and B. Conclusions This study shows that, for a 30-minute prediction horizon, data-driven AR models provide sufficiently-accurate and clinically-acceptable estimates of glucose levels for timely, proactive therapy and should be considered as the modeling engine for predictive monitoring of patients with type 1 diabetes mellitus. It also suggests that AR models can be made portable from individual to individual with minor performance penalties, while greatly reducing the burden associated with model tuning and data collection for model development. PMID:19885110

A SHORT HISTORY AND CRITICAL REVIEW OF INDIVIDUAL MONITORING.

PubMed

Wernli, Christian

2016-09-01

Soon after the discovery of X-rays and the radioactive element radium harmful radiation effects occurred, mainly in the medical field. Consequently, the radiologists, a new profession at that time, called for a limitation of radiation exposures. First proposals were to limit the exposure rate to prevent the incidence of skin erythema. It took more than two decades and there were many victims of severe radiation effects until a sound basis for radiation protection and individual monitoring was established. For external dosimetry, the film dosemeter was invented in the 1920s. This device, often combined with an ion chamber-based pencil dosemeter, dominated the systems used in personnel dosimetry until the end of the twentieth century. For internal exposure, the concept of limiting the 'body burden' was commonly used, and only in the late 1970s, the new concept of the 'effective dose equivalent' published in ICRP publication 26 allowed for a unified interpretation and, therefore, addition of the dosimetric quantities for external and internal exposures. By the end of the last century, individual monitoring had to survive an inflation of proposals for new quantities, but fortunately, it was also the time of vast developments of new technologies, methods and procedures. Later on, much room was given to highly sophisticated regulations, requirements, metrological concepts and administrative procedures. In this complex environment, the original task of individual monitoring became more and more hidden behind secondary loads. Now, like about hundred years ago, however with different motivation, once again the ultimate goal of the professional work has to be thought about by asking: Do people always know why they do what they do? Or simply: Why individual monitoring? © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Automated Internet-Based Control of Spacecraft Groundstations: Beacon-Based Health Monitoring Concept

NASA Technical Reports Server (NTRS)

Cantwell, Brian; Twiggs, Robert; Swartwout, Michael

1997-01-01

This report serves as an update about the activities of Stanford University's Space Systems Development Laboratory (SSDL) in their beacon-based health monitoring experiment. Section 1 describes the goals of the project and the organization of the team. Section 2 provides an overview of the major components of the system, describing the general approach of automated health monitoring and the beacon signal relay. It also provides background about the SAPPHIRE spacecraft and ASSET operations system, which will be used for the experiment. Specific details about implementation and status of each element of the experiment are found in Section 3. Section 4 describes the experiment and future work, and references are contained in Section 5.

The awakening of the attention: Evidence for a link between the monitoring of mind wandering and prospective goals.

PubMed

Seli, Paul; Smilek, Daniel; Ralph, Brandon C W; Schacter, Daniel L

2018-03-01

Across 2 independent samples, we examined the relation between individual differences in rates of self-caught mind wandering and individual differences in temporal monitoring of an unrelated response goal. Rates of self-caught mind wandering were assessed during a commonly used sustained-attention task, and temporal goal monitoring was indexed during a well-established prospective-memory task. The results from both samples showed a positive relation between rates of self-caught mind wandering during the sustained-attention task and rates of checking a clock to monitor the amount of time remaining before a response was required in the prospective-memory task. This relation held even when controlling for overall propensity to mind-wander (indexed by intermittent thought probes) and levels of motivation (indexed by subjective reports). These results suggest the possibility that there is a common monitoring system that monitors the contents of consciousness and the progress of ongoing goals and tasks. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

A history of continuous glucose monitors (CGMs) in self-monitoring of diabetes mellitus.

PubMed

Olczuk, David; Priefer, Ronny

Self-monitoring of glucose for individuals afflicted with diabetes mellitus has allowed patients to take control of their disease and thus directly affect the outcomes related to it. It has been almost a century since the first test to monitor one's sugar was developed; that being a urine test. The most well-known and prominent medical device for monitor blood glucose for individuals with diabetes are the finger-prick devices. This itself is an approximately 50year old technology. More recently has been the introduction of continuous glucose monitors (CGMs) which entered the market place in the last year of the 20th century. As this technology has been further refined and improved, limitations associated with it have decreased. The scope of this review is to present a brief history of CGMs, both with the development of these medical devices and the challenges/limitations that they have shown. Copyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Georgia's Stream-Water-Quality Monitoring Network, 2006

USGS Publications Warehouse

Nobles, Patricia L.; ,

2006-01-01

The USGS stream-water-quality monitoring network for Georgia is an aggregation of smaller networks and individual monitoring stations that have been established in cooperation with Federal, State, and local agencies. These networks collectively provide data from 130 sites, 62 of which are monitored continuously in real time using specialized equipment that transmits these data via satellite to a centralized location for processing and storage. These data are made available on the Web in near real time at http://waterdata.usgs.gov/ga/nwis/ Ninety-eight stations are sampled periodically for a more extensive suite of chemical and biological constituents that require laboratory analysis. Both the continuous and the periodic water-quality data are archived and maintained in the USGS National Water Information System and are available to cooperators, water-resource managers, and the public. The map at right shows the USGS stream-water-quality monitoring network for Georgia and major watersheds. The network represents an aggregation of smaller networks and individual monitoring stations that collectively provide data from 130 sites.

Confident failures: Lapses of working memory reveal a metacognitive blind spot.

PubMed

Adam, Kirsten C S; Vogel, Edward K

2017-07-01

Working memory performance fluctuates dramatically from trial to trial. On many trials, performance is no better than chance. Here, we assessed participants' awareness of working memory failures. We used a whole-report visual working memory task to quantify both trial-by-trial performance and trial-by-trial subjective ratings of inattention to the task. In Experiment 1 (N = 41), participants were probed for task-unrelated thoughts immediately following 20% of trials. In Experiment 2 (N = 30), participants gave a rating of their attentional state following 25% of trials. Finally, in Experiments 3a (N = 44) and 3b (N = 34), participants reported confidence of every response using a simple mouse-click judgment. Attention-state ratings and off-task thoughts predicted the number of items correctly identified on each trial, replicating previous findings that subjective measures of attention state predict working memory performance. However, participants correctly identified failures on only around 28% of failure trials. Across experiments, participants' metacognitive judgments reliably predicted variation in working memory performance but consistently and severely underestimated the extent of failures. Further, individual differences in metacognitive accuracy correlated with overall working memory performance, suggesting that metacognitive monitoring may be key to working memory success.

Monitoring of the infrastructure and services used to handle and automatically produce Alignment and Calibration conditions at CMS

NASA Astrophysics Data System (ADS)

Sipos, Roland; Govi, Giacomo; Franzoni, Giovanni; Di Guida, Salvatore; Pfeiffer, Andreas

2017-10-01

The CMS experiment at CERN LHC has a dedicated infrastructure to handle the alignment and calibration data. This infrastructure is composed of several services, which take on various data management tasks required for the consumption of the non-event data (also called as condition data) in the experiment activities. The criticality of these tasks imposes tights requirements for the availability and the reliability of the services executing them. In this scope, a comprehensive monitoring and alarm generating system has been developed. The system has been implemented based on the Nagios open source industry standard for monitoring and alerting services, and monitors the database back-end, the hosting nodes and key heart-beat functionalities for all the services involved. This paper describes the design, implementation and operational experience with the monitoring system developed and deployed at CMS in 2016.

Form Overrides Meaning When Bilinguals Monitor for Errors

PubMed Central

Ivanova, Iva; Ferreira, Victor S.; Gollan, Tamar H.

2016-01-01

Bilinguals rarely produce unintended language switches, which may in part be because switches are detected and corrected by an internal monitor. But are language switches easier or harder to detect than within-language semantic errors? To approximate internal monitoring, bilinguals listened (Experiment 1) or read aloud (Experiment 2) stories, and detected language switches (translation equivalents or semantically unrelated to expected words) and within-language errors (semantically related or unrelated to expected words). Bilinguals detected semantically related within-language errors most slowly and least accurately, language switches more quickly and accurately than within-language errors, and (in Experiment 2), translation equivalents as quickly and accurately as unrelated language switches. These results suggest that internal monitoring of form (which can detect mismatches in language membership) completes earlier than, and is independent of, monitoring of meaning. However, analysis of reading times prior to error detection revealed meaning violations to be more disruptive for processing than language violations. PMID:28649169

Chemical Explosion Experiments to Improve Nuclear Test Monitoring [Developing a New Paradigm for Nuclear Test Monitoring with the Source Physics Experiments (SPE)

DOE PAGES

Snelson, Catherine M.; Abbott, Robert E.; Broome, Scott T.; ...

2013-07-02

A series of chemical explosions, called the Source Physics Experiments (SPE), is being conducted under the auspices of the U.S. Department of Energy’s National Nuclear Security Administration (NNSA) to develop a new more physics-based paradigm for nuclear test monitoring. Currently, monitoring relies on semi-empirical models to discriminate explosions from earthquakes and to estimate key parameters such as yield. While these models have been highly successful monitoring established test sites, there is concern that future tests could occur in media and at scale depths of burial outside of our empirical experience. This is highlighted by North Korean tests, which exhibit poormore » performance of a reliable discriminant, mb:Ms (Selby et al., 2012), possibly due to source emplacement and differences in seismic responses for nascent and established test sites. The goal of SPE is to replace these semi-empirical relationships with numerical techniques grounded in a physical basis and thus applicable to any geologic setting or depth.« less

Are all judgments created equal? An fMRI study of semantic and episodic metamemory predictions.

PubMed

Reggev, Niv; Zuckerman, Maya; Maril, Anat

2011-04-01

Metamemory refers to the ability of individuals to monitor and control their own memory performance. Although little theoretical consideration of the possible differences between the monitoring of episodic and of semantic knowledge has been published, results from patient and drug studies that used the "feeling of knowing" (FOK) paradigm show a selective impairment in the accuracy of episodic monitoring but not in its semantic counterpart. Similarly, neuroimaging studies provide indirect evidence for separate patterns of activation during episodic or semantic FOKs. However, the semantic-episodic distinction hypothesis has not been directly addressed. In the current event-related fMRI study, we used a within-subject, within-experiment comparison of the monitoring of semantic and episodic content. Whereas the common neural correlates of episodic and semantic FOKs observed in this study generally replicate the previous neuroimaging findings, several regions were found to be differentially associated with each task. Activity of the right inferior frontal gyrus was modulated by the semantic-episodic factor only during the negative predictions of retrieval, suggesting that negative predictions are based on partially distinct mechanisms during each task. A posterior midline network, known to be activated during episodic retrieval, was activated during episodic and not semantic monitoring, suggesting that episodic FOKs rely, to some extent, on common episodic retrieval processes. These findings suggest that theoretical accounts of the etiology and function of FOKs may benefit from incorporating the prediction directionality (positive/negative) and the memory domain (semantic/episodic) distinctions. Copyright © 2011 Elsevier Ltd. All rights reserved.

'Knowing where I am': self-monitoring of blood glucose in diabetes.

PubMed

Meetoo, Danny; Wong, Louise; Fatani, Tughreed

2018-05-24

Although the prevalence of all types of chronic conditions is increasing, diabetes is one of the few long-term metabolic disorders that individuals can successfully manage, monitor and control on a day-to-day basis. Self-monitoring of blood glucose (SMBG) is considered an essential component of diabetes self-care management. When used appropriately, SMBG can help to identify factors associated with hyper- and hypoglycaemia, facilitate learning, and empower people with diabetes to make changes to improve their glycaemic control. SMBG can be a useful tool for healthcare providers, who can teach individuals to monitor glucose at specific times to assess the effectiveness of medications and guide medication management. However, there is an ongoing debate regarding whether, as is the case with type 1 diabetes, all people with type 2 diabetes should also be given the opportunity to learn about the value of, and skills required to, monitor blood glucose as appropriate to their specific needs.

An integrated sampling and analysis approach for improved biodiversity monitoring

USGS Publications Warehouse

DeWan, Amielle A.; Zipkin, Elise

2010-01-01

Successful biodiversity conservation requires high quality monitoring data and analyses to ensure scientifically defensible policy, legislation, and management. Although monitoring is a critical component in assessing population status and trends, many governmental and non-governmental organizations struggle to develop and implement effective sampling protocols and statistical analyses because of the magnitude and diversity of species in conservation concern. In this article we describe a practical and sophisticated data collection and analysis framework for developing a comprehensive wildlife monitoring program that includes multi-species inventory techniques and community-level hierarchical modeling. Compared to monitoring many species individually, the multi-species approach allows for improved estimates of individual species occurrences, including rare species, and an increased understanding of the aggregated response of a community to landscape and habitat heterogeneity. We demonstrate the benefits and practicality of this approach to address challenges associated with monitoring in the context of US state agencies that are legislatively required to monitor and protect species in greatest conservation need. We believe this approach will be useful to regional, national, and international organizations interested in assessing the status of both common and rare species.

Event-related brain potentials that distinguish false memory for events that occurred only seconds in the past.

PubMed

Chen, Hong; Voss, Joel L; Guo, Chunyan

2012-07-30

False memory often involves retrieving events from the distant past that did not actually happen. However, recent evidence obtained using the Deese/Roediger-McDermott (DRM) paradigm for eliciting false memory experiences suggests that individuals can falsely believe that events occurred mere seconds in the past when they in fact did not. Subjects in these experiments endorsed unstudied critical lure words as having been studied, despite the fact that word lists were studied just moments before. We identified event-related brain potential (ERP) correlates of this experience, and included a repetition priming manipulation to better assess the functional significance of these ERPs. Behavioral and ERP data were collected from 21 Capital Normal University students using a short-term DRM task. Two categories of effects were identified that distinguished true from false short-term memory: (1) early semantic priming effects from 300 to 500 ms and (2) later retrieval and retrieval-monitoring effects after 500 ms. The repetition priming manipulation had distinct influences on these effects, consistent with their differential associations with semantic priming versus episodic retrieval. Characterization of ERPs related to semantic priming and episodic retrieval provides important information regarding the mechanisms of short-term false memory. In contrast, most studies examining false memory in standard long-delay DRM paradigms identify ERP effects related only to retrieval monitoring. These findings highlight the neural processing involved in illusions of memory after very brief delays and highlight the role of semantic processing in short-term false memory.