Automatic alignment of individual peaks in large high-resolution spectral data sets

NASA Astrophysics Data System (ADS)

Stoyanova, Radka; Nicholls, Andrew W.; Nicholson, Jeremy K.; Lindon, John C.; Brown, Truman R.

2004-10-01

Pattern recognition techniques are effective tools for reducing the information contained in large spectral data sets to a much smaller number of significant features which can then be used to make interpretations about the chemical or biochemical system under study. Often the effectiveness of such approaches is impeded by experimental and instrument induced variations in the position, phase, and line width of the spectral peaks. Although characterizing the cause and magnitude of these fluctuations could be important in its own right (pH-induced NMR chemical shift changes, for example) in general they obscure the process of pattern discovery. One major area of application is the use of large databases of 1H NMR spectra of biofluids such as urine for investigating perturbations in metabolic profiles caused by drugs or disease, a process now termed metabonomics. Frequency shifts of individual peaks are the dominant source of such unwanted variations in this type of data. In this paper, an automatic procedure for aligning the individual peaks in the data set is described and evaluated. The proposed method will be vital for the efficient and automatic analysis of large metabonomic data sets and should also be applicable to other types of data.

Compensation of flare-induced CD changes EUVL

DOEpatents

Bjorkholm, John E [Pleasanton, CA; Stearns, Daniel G [Los Altos, CA; Gullikson, Eric M [Oakland, CA; Tichenor, Daniel A [Castro Valley, CA; Hector, Scott D [Oakland, CA

2004-11-09

A method for compensating for flare-induced critical dimensions (CD) changes in photolithography. Changes in the flare level results in undesirable CD changes. The method when used in extreme ultraviolet (EUV) lithography essentially eliminates the unwanted CD changes. The method is based on the recognition that the intrinsic level of flare for an EUV camera (the flare level for an isolated sub-resolution opaque dot in a bright field mask) is essentially constant over the image field. The method involves calculating the flare and its variation over the area of a patterned mask that will be imaged and then using mask biasing to largely eliminate the CD variations that the flare and its variations would otherwise cause. This method would be difficult to apply to optical or DUV lithography since the intrinsic flare for those lithographies is not constant over the image field.

Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population.

PubMed

Ivannikov, Alexander I; Khailov, Artem M; Orlenko, Sergey P; Skvortsov, Valeri G; Stepanenko, Valeri F; Zhumadilov, Kassym Sh; Williams, Benjamin B; Flood, Ann B; Swartz, Harold M

2016-12-01

The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y -1 , the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose-response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its variation correspond to 4.0 ± 0.4 (SD = 1.0) Gy. © Crown copyright 2016.

Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population

PubMed Central

Ivannikov, Alexander I.; Khailov, Artem M.; Orlenko, Sergey P.; Skvortsov, Valeri G.; Stepanenko, Valeri F.; Zhumadilov, Kassym Sh.; Williams, Benjamin B.; Flood, Ann B.; Swartz, Harold M.

2016-01-01

The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y−1, the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose–response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its variation correspond to 4.0 ± 0.4 (SD = 1.0) Gy. PMID:27412516

A search for relativistic electron induced stratospheric ozone depletion

NASA Technical Reports Server (NTRS)

Aikin, Arthur C.

1994-01-01

Possible ozone changes at 1 mb associated with the time variation and precipitation of relativistic electrons are investigated by examining the NIMBUS 7 SBUV ozone data set and corresponding temperatures derived from NMC data. No ozone depletion was observed in high-latitude summer when temperature fluctuations are small. In winter more variation in ozone occurs, but large temperature changes make it difficult to identify specific ozone decreases as being the result of relativistic electron precipitation.

Natural and human-induced terrestrial water storage change: A global analysis using hydrological models and GRACE

NASA Astrophysics Data System (ADS)

Felfelani, Farshid; Wada, Yoshihide; Longuevergne, Laurent; Pokhrel, Yadu N.

2017-10-01

Hydrological models and the data derived from the Gravity Recovery and Climate Experiment (GRACE) satellite mission have been widely used to study the variations in terrestrial water storage (TWS) over large regions. However, both GRACE products and model results suffer from inherent uncertainties, calling for the need to make a combined use of GRACE and models to examine the variations in total TWS and their individual components, especially in relation to natural and human-induced changes in the terrestrial water cycle. In this study, we use the results from two state-of-the-art hydrological models and different GRACE spherical harmonic products to examine the variations in TWS and its individual components, and to attribute the changes to natural and human-induced factors over large global river basins. Analysis of the spatial patterns of the long-term trend in TWS from the two models and GRACE suggests that both models capture the GRACE-measured direction of change, but differ from GRACE as well as each other in terms of the magnitude over different regions. A detailed analysis of the seasonal cycle of TWS variations over 30 river basins shows notable differences not only between models and GRACE but also among different GRACE products and between the two models. Further, it is found that while one model performs well in highly-managed river basins, it fails to reproduce the GRACE-observed signal in snow-dominated regions, and vice versa. The isolation of natural and human-induced changes in TWS in some of the managed basins reveals a consistently declining TWS trend during 2002-2010, however; significant differences are again obvious both between GRACE and models and among different GRACE products and models. Results from the decomposition of the TWS signal into the general trend and seasonality indicate that both models do not adequately capture both the trend and seasonality in the managed or snow-dominated basins implying that the TWS variations from a single model cannot be reliably used for all global regions. It is also found that the uncertainties arising from climate forcing datasets can introduce significant additional uncertainties, making direct comparison of model results and GRACE products even more difficult. Our results highlight the need to further improve the representation of human land-water management and snow processes in large-scale models to enable a reliable use of models and GRACE to study the changes in freshwater systems in all global regions.

Interfacial Characteristics of Efficient Bulk Heterojunction Solar Cells Fabricated on MoOx Anode Interlayers.

PubMed

Jasieniak, Jacek J; Treat, Neil D; McNeill, Christopher R; de Villers, Bertrand J Tremolet; Della Gaspera, Enrico; Chabinyc, Michael L

2016-05-01

The role of the interface between an MoOx anode interlayer and a polymer:fullerene bulk heterojunction is investigated. Processing differences in the MoOx induce large variations in the vertical stratification of the bulk heterojunction films. These variations are found to be inconsistent in predicting device performance, with a much better gauge being the quantity of polymer chemisorbed to the anode interlayer. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Simultaneous Study of Intake and In-Cylinder IC Engine Flow Fields to Provide an Insight into Intake Induced Cyclic Variations

NASA Astrophysics Data System (ADS)

Justham, T.; Jarvis, S.; Clarke, A.; Garner, C. P.; Hargrave, G. K.; Halliwell, N. A.

2006-07-01

Simultaneous intake and in-cylinder digital particle image velocimetry (DPIV) experimental data is presented for a motored spark ignition (SI) optical internal combustion (IC) engine. Two individual DPIV systems were employed to study the inter-relationship between the intake and in-cylinder flow fields at an engine speed of 1500 rpm. Results for the intake runner velocity field at the time of maximum intake valve lift are compared to incylinder velocity fields later in the same engine cycle. Relationships between flow structures within the runner and cylinder were seen to be strong during the intake stroke but less significant during compression. Cyclic variations within the intake runner were seen to affect the large scale bulk flow motion. The subsequent decay of the large scale motions into smaller scale turbulent structures during the compression stroke appear to reduce the relationship with the intake flow variations.

Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening: A Modeling Study.

PubMed

Miglioretti, Diana L; Lange, Jane; van den Broek, Jeroen J; Lee, Christoph I; van Ravesteyn, Nicolien T; Ritley, Dominique; Kerlikowske, Karla; Fenton, Joshua J; Melnikow, Joy; de Koning, Harry J; Hubbard, Rebecca A

2016-02-16

Estimates of risk for radiation-induced breast cancer from mammography screening have not considered variation in dose exposure or diagnostic work-up after abnormal screening results. To estimate distributions of radiation-induced breast cancer incidence and mortality from digital mammography screening while considering exposure from screening and diagnostic mammography and dose variation among women. 2 simulation-modeling approaches. U.S. population. Women aged 40 to 74 years. Annual or biennial digital mammography screening from age 40, 45, or 50 years until age 74 years. Lifetime breast cancer deaths averted (benefits) and radiation-induced breast cancer incidence and mortality (harms) per 100,000 women screened. Annual screening of 100,000 women aged 40 to 74 years was projected to induce 125 breast cancer cases (95% CI, 88 to 178) leading to 16 deaths (CI, 11 to 23), relative to 968 breast cancer deaths averted by early detection from screening. Women exposed at the 95th percentile were projected to develop 246 cases of radiation-induced breast cancer leading to 32 deaths per 100,000 women. Women with large breasts requiring extra views for complete examination (8% of population) were projected to have greater radiation-induced breast cancer risk (266 cancer cases and 35 deaths per 100,000 women) than other women (113 cancer cases and 15 deaths per 100,000 women). Biennial screening starting at age 50 years reduced risk for radiation-induced cancer 5-fold. Life-years lost from radiation-induced breast cancer could not be estimated. Radiation-induced breast cancer incidence and mortality from digital mammography screening are affected by dose variability from screening, resultant diagnostic work-up, initiation age, and screening frequency. Women with large breasts may have a greater risk for radiation-induced breast cancer. Agency for Healthcare Research and Quality, U.S. Preventive Services Task Force, National Cancer Institute.

Large Drought-Induced Variations in Oak Leaf Volatile Organic Compound Emissions during PINOT NOIR 2012

EPA Science Inventory

Leaf-level isoprene and monoterpene emissions were collected and analyzed from five of the most abundant oak (Quercus) species in Central Missouri’s Ozarks Region in 2012 during PINOT NOIR (Particle Investigations at a Northern Ozarks Tower ‐ NOx, Oxidants, Isoprene Research). Ju...

Effects of variables upon pyrotechnically induced shock response spectra, part 2

NASA Technical Reports Server (NTRS)

Smith, James Lee

1988-01-01

Throughout the aerospace industry, large variations of 50 percent (6 dB) or more in shock response spectra (SRS) derived from pyrotechnic separation events continue to be reported from actual spaceflight data and from laboratory tests. As a result of these variations, NASA funded a research program for 1984 through 1986. The purpose of the 1984 through 1986 project was to analyze variations in pyrotechnically induced SRS and to determine if and to what degree manufacturing and assembly variables and tolerances, distance from the shock source, data acquisition instrumentation, and shock energy propagation affect the SRS. Sixty-four free-free boundary plate tests were performed. NASA funded an additional study for 1987 through 1988. This paper is a summary of the additional study. The purpose was to evaluate shock dissipation through various spacecraft structural joint types, to evaluate shock variation for various manufacturing and assembly variables on clamped boundary test plates, and to verify data correction techniques. Five clamped boundary plate tests investigated manufacturing and assembly variables and mass loading effects. Six free-free boundary plate tests investigated shock dissipation across spacecraft joint structures.

Genomic variation and DNA repair associated with soybean transgenesis: a comparison to cultivars and mutagenized plants.

PubMed

Anderson, Justin E; Michno, Jean-Michel; Kono, Thomas J Y; Stec, Adrian O; Campbell, Benjamin W; Curtin, Shaun J; Stupar, Robert M

2016-05-12

The safety of mutagenized and genetically transformed plants remains a subject of scrutiny. Data gathered and communicated on the phenotypic and molecular variation induced by gene transfer technologies will provide a scientific-based means to rationally address such concerns. In this study, genomic structural variation (e.g. large deletions and duplications) and single nucleotide polymorphism rates were assessed among a sample of soybean cultivars, fast neutron-derived mutants, and five genetically transformed plants developed through Agrobacterium based transformation methods. On average, the number of genes affected by structural variations in transgenic plants was one order of magnitude less than that of fast neutron mutants and two orders of magnitude less than the rates observed between cultivars. Structural variants in transgenic plants, while rare, occurred adjacent to the transgenes, and at unlinked loci on different chromosomes. DNA repair junctions at both transgenic and unlinked sites were consistent with sequence microhomology across breakpoints. The single nucleotide substitution rates were modest in both fast neutron and transformed plants, exhibiting fewer than 100 substitutions genome-wide, while inter-cultivar comparisons identified over one-million single nucleotide polymorphisms. Overall, these patterns provide a fresh perspective on the genomic variation associated with high-energy induced mutagenesis and genetically transformed plants. The genetic transformation process infrequently results in novel genetic variation and these rare events are analogous to genetic variants occurring spontaneously, already present in the existing germplasm, or induced through other types of mutagenesis. It remains unclear how broadly these results can be applied to other crops or transformation methods.

SERS of Methylene Blue induced by plasmonic coupled nanoparticle arrays

NASA Astrophysics Data System (ADS)

Kaydashev, V. E.; Lyanguzov, N. V.; Anokhin, A. S.; Chernishov, A.; Kaidashev, E. M.

2018-04-01

We study the surface enhanced Raman scattering of Methylene Blue (MB) dye molecules induced by large quasihomogeneous arrays of plasmon coupled 5-8 nm Au nanoparticle separated by distances less than 10 nm. Also, the variation of the fluorescence enhancement/SERS properties for as-prepared coupled particles and agglomerated particles obtained upon heat treatment and percolation-like films is analyzed for two measurement protocols, i.e. when measured through the solution and for a monolayer of MB molecules chemisorbed on a surface.

Engineering functionality gradients by dip coating process in acceleration mode.

PubMed

Faustini, Marco; Ceratti, Davide R; Louis, Benjamin; Boudot, Mickael; Albouy, Pierre-Antoine; Boissière, Cédric; Grosso, David

2014-10-08

In this work, unique functional devices exhibiting controlled gradients of properties are fabricated by dip-coating process in acceleration mode. Through this new approach, thin films with "on-demand" thickness graded profiles at the submillimeter scale are prepared in an easy and versatile way, compatible for large-scale production. The technique is adapted to several relevant materials, including sol-gel dense and mesoporous metal oxides, block copolymers, metal-organic framework colloids, and commercial photoresists. In the first part of the Article, an investigation on the effect of the dip coating speed variation on the thickness profiles is reported together with the critical roles played by the evaporation rate and by the viscosity on the fluid draining-induced film formation. In the second part, dip-coating in acceleration mode is used to induce controlled variation of functionalities by playing on structural, chemical, or dimensional variations in nano- and microsystems. In order to demonstrate the full potentiality and versatility of the technique, original graded functional devices are made including optical interferometry mirrors with bidirectional gradients, one-dimensional photonic crystals with a stop-band gradient, graded microfluidic channels, and wetting gradient to induce droplet motion.

Spatiotemporal Changes of Cyanobacterial Bloom in Large Shallow Eutrophic Lake Taihu, China

PubMed Central

Qin, Boqiang; Yang, Guijun; Ma, Jianrong; Wu, Tingfeng; Li, Wei; Liu, Lizhen; Deng, Jianming; Zhou, Jian

2018-01-01

Lake Taihu is a large shallow eutrophic lake with frequent recurrence of cyanobacterial bloom which has high variable distribution in space and time. Based on the field observations and remote sensing monitoring of cyanobacterial bloom occurrence, in conjunction with laboratory controlled experiments of mixing effects on large colony formation and colonies upward moving velocity measurements, it is found that the small or moderate wind-induced disturbance would increase the colonies size and enable it more easily to overcome the mixing and float to water surface rapidly during post-disturbance. The proposed mechanism of wind induced mixing on cyanobacterial colony enlargement is associated with the presence of the extracellular polysaccharide (EPS) which increased the size and buoyancy of cyanobacteria colonies and promote the colonies aggregate at the water surface to form bloom. Both the vertical movement and horizontal migration of cyanobacterial colonies were controlled by the wind induced hydrodynamics. Because of the high variation of wind and current coupling with the large cyanobacterial colony formation make the bloom occurrence as highly mutable in space and time. This physical factor determining cyanobacterial bloom formation in the large shallow lake differ from the previously documented light-mediated bloom formation dynamics. PMID:29619011

Internal friction peaks observed in explosively deformed polycrystalline Mo, Nb, and Cu

NASA Technical Reports Server (NTRS)

Rieu, G. E.; Grimes, H. H.; Romain, J. P.; Defouquet, J.

1974-01-01

Explosive deformation (50 kbar range) induced, in Cu, Mo and Nb, internal friction peaks identical to those observed after large normal deformation. The variation of the peaks with pressure for Mo and Nb lead to an explanation of these processes in terms of double kink generation in screw and edge dislocations.

A strong correlation between induced peak dynamic Coulomb stress change from the 1992 M7.3 Landers, California, earthquake and the hypocenter of the 1999 M7.1 Hector Mine, California, earthquake

NASA Astrophysics Data System (ADS)

Kilb, Debi

2003-01-01

The 1992 M7.3 Landers earthquake may have played a role in triggering the 1999 M7.1 Hector Mine earthquake as suggested by their close spatial (˜20 km) proximity. Current investigations of triggering by static stress changes produce differing conclusions when small variations in parameter values are employed. Here I test the hypothesis that large-amplitude dynamic stress changes, induced by the Landers rupture, acted to promote the Hector Mine earthquake. I use a flat layer reflectivity method to model the Landers earthquake displacement seismograms. By requiring agreement between the model seismograms and data, I can constrain the Landers main shock parameters and velocity model. A similar reflectivity method is used to compute the evolution of stress changes. I find a strong positive correlation between the Hector Mine hypocenter and regions of large (>4 MPa) dynamic Coulomb stress changes (peak Δσf(t)) induced by the Landers main shock. A positive correlation is also found with large dynamic normal and shear stress changes. Uncertainties in peak Δσf(t) (1.3 MPa) are only 28% of the median value (4.6 MPa) determined from an extensive set (160) of model parameters. Therefore the correlation with dynamic stresses is robust to a range of Hector Mine main shock parameters, as well as to variations in the friction and Skempton's coefficients used in the calculations. These results imply dynamic stress changes may be an important part of earthquake trigging, such that large-amplitude stress changes alter the properties of an existing fault in a way that promotes fault failure.

Alternative pathway regulation by factor H modulates Streptococcus pneumoniae induced proinflammatory cytokine responses by decreasing C5a receptor crosstalk.

PubMed

van der Maten, Erika; de Bont, Cynthia M; de Groot, Ronald; de Jonge, Marien I; Langereis, Jeroen D; van der Flier, Michiel

2016-12-01

Bacterial pathogens not only stimulate innate immune receptors, but also activate the complement system. Crosstalk between complement C5a receptor (C5aR) and other innate immune receptors is known to enhance the proinflammatory cytokine response. An important determinant of the magnitude of complement activation is the activity of the alternative pathway, which serves as an amplification mechanism for complement activation. Both alternative pathway activity as well as plasma levels of factor H, a key inhibitor of the alternative pathway, show large variation within the human population. Here, we studied the effect of factor H-mediated regulation of the alternative pathway on bacterial-induced proinflammatory cytokine responses. We used the human pathogen Streptococcus pneumoniae as a model stimulus to induce proinflammatory cytokine responses in human peripheral blood mononuclear cells. Serum containing active complement enhanced pneumococcal induced proinflammatory cytokine production through C5a release and C5aR crosstalk. We found that inhibition of the alternative pathway by factor H, with a concentration equivalent to a high physiological level, strongly reduced C5a levels and decreased proinflammatory cytokine production in human peripheral blood mononuclear cells. This suggests that variation in alternative pathway activity due to variation in factor H plasma levels affects individual cytokine responses during infection. Copyright © 2016 Elsevier Ltd. All rights reserved.

Global variations of zonal mean ozone during stratospheric warming events

NASA Technical Reports Server (NTRS)

Randel, William J.

1993-01-01

Eight years of Solar Backscatter Ultraviolet (SBUV) ozone data are examined to study zonal mean variations associated with stratospheric planetary wave (warming) events. These fluctuations are found to be nearly global in extent, with relatively large variations in the tropics, and coherent signatures reaching up to 50 deg in the opposite (summer) hemisphere. These ozone variations are a manifestation of the global circulation cells associated with stratospheric warming events; the ozone responds dynamically in the lower stratosphere to transport, and photochemically in the upper stratosphere to the circulation-induced temperature changes. The observed ozone variations in the tropics are of particular interest because transport is dominated by zonal-mean vertical motions (eddy flux divergences and mean meridional transports are negligible), and hence, substantial simplifications to the governing equations occur. The response of the atmosphere to these impulsive circulation changes provides a situation for robust estimates of the ozone-temperature sensitivity in the upper stratosphere.

On the origin of multi-decadal to centennial Greenland temperature anomalies over the past 800 yr

NASA Astrophysics Data System (ADS)

Kobashi, T.; Shindell, D. T.; Kodera, K.; Box, J. E.; Nakaegawa, T.; Kawamura, K.

2012-11-01

The surface temperature of the Greenland ice sheet is among the most important climate variables for assessing how climate change may impact human societies associated with accelerating sea level rise. However, the causes of multi-decadal-to-centennial temperature changes in Greenland are not well understood, largely owing to short observational records. To examine the causes of the Greenland temperature variability, we calculated the Greenland temperature anomalies (GTA(G-NH)) over the past 800 yr by subtracting the standardised NH temperature from the standardised Greenland temperature. It decomposes the Greenland temperature variation into background climate (NH); Polar amplification; and Regional variability (GTA(G-NH)). The Central Greenland polar amplification factor as expressed by the variance ratio = Greenland/NH is 2.6 over the past 161 yr, and 3.3-4.2 over the past 800 yr. The GTA explains 31-35% of the variation of Greenland temperature in the multi-decadal-to-centennial time scale over the past 800 yr. Another orthogonal component of the Greenland and NH temperatures, GTP(G+NH) (Greenland temperature plus = standardized Greenland temperature + standardized NH temperature) exhibited the multi-decadal variations that were likely induced by large volcanic eruptions, increasing greenhouse gasses, and internal variation of climate. We found that the GTA(G-NH) has been influenced by solar-induced changes in atmospheric circulation patterns such as those produced by North Atlantic Oscillation/Arctic Oscillation (NAO/AO). Climate modelling indicates that the anomaly is also likely linked to solar-paced changes in the Atlantic meridional overturning circulation (AMOC) and to associated changes in northward oceanic heat transport.

Medium and large-scale variations of dynamo-induced electric fields from AE ion drift measurements

NASA Technical Reports Server (NTRS)

Coley, W. R.; Mcclure, J. P.

1986-01-01

Current models of the low latitude electric field are largely based on data from incoherent scatter radars. These observations are extended through the addition of the rather extensive high quality electric field measurements from the Ion Drift Meter (IDM) aboard the Atmosphere Explorer (AE) spacecraft. Some preliminary results obtained from the Unified Abstract files of satellite AE-E are presented. This satellite was active from the end of 1975 through June 1981 in various elliptical and circular orbits having an inclination near 20 deg. The resulting data can be examined for the variation of ion drift with latitude, longitude, season, solar cycle, altitude, and magnetic activity. The results presented deal primarily with latitudinal variations of the drift features. Diagrams of data are given and briefly interpreted. The preliminary results presented here indicate that IDM data from the AE and the more recent Dynamics Explorer B spacecraft should continue to disclose some interesting and previously unobserved dynamical features of the low latitude F region.

An investigation into the induced electric fields from transcranial magnetic stimulation

NASA Astrophysics Data System (ADS)

Hadimani, Ravi; Lee, Erik; Duffy, Walter; Waris, Mohammed; Siddiqui, Waquar; Islam, Faisal; Rajamani, Mahesh; Nathan, Ryan; Jiles, David; David C Jiles Team; Walter Duffy Collaboration

Transcranial magnetic stimulation (TMS) is a promising tool for noninvasive brain stimulation that has been approved by the FDA for the treatment of major depressive disorder. To stimulate the brain, TMS uses large, transient pulses of magnetic field to induce an electric field in the head. This transient magnetic field is large enough to cause the depolarization of cortical neurons and initiate a synaptic signal transmission. For this study, 50 unique head models were created from MRI images. Previous simulation studies have primarily used a single head model, and thus give a limited image of the induced electric field from TMS. This study uses finite element analysis simulations on 50 unique, heterogeneous head models to better investigate the relationship between TMS and the electric field induced in brain tissues. Results showed a significant variation in the strength of the induced electric field in the brain, which can be reasonably predicted by the distance from the TMS coil to the stimulated brain. Further, it was seen that some models had high electric field intensities in over five times as much brain volume as other models.

Radiation-Induced Breast Cancer Incidence and Mortality from Digital Mammography Screening: A Modeling Study

PubMed Central

Miglioretti, Diana L.; Lange, Jane; van den Broek, Jeroen J.; Lee, Christoph I.; van Ravesteyn, Nicolien T.; Ritley, Dominique; Kerlikowske, Karla; Fenton, Joshua J.; Melnikow, Joy; de Koning, Harry J.; Hubbard, Rebecca A.

2016-01-01

Background Estimates of radiation-induced breast cancer risk from mammography screening have not previously considered dose exposure variation or diagnostic work-up after abnormal screening. Objective To estimate distributions of radiation-induced breast cancer incidence and mortality from digital mammography screening, considering exposure from screening and diagnostic mammography and dose variation across women. Design Two simulation-modeling approaches using common data on screening mammography from the Breast Cancer Surveillance Consortium and radiation dose from mammography from the Digital Mammographic Imaging Screening Trial. Setting U.S. population. Patients Women aged 40–74 years. Interventions Annual or biennial digital mammography screening from age 40, 45, or 50 until 74. Measurements Lifetime breast cancer deaths averted (benefits) and radiation-induced breast cancer incidence and mortality per 100,000 women screened (harms). Results On average, annual screening of 100,000 women aged 40 to 74 years was projected to induce 125 breast cancers (95% confidence interval [CI]=88–178) leading to 16 deaths (95% CI=11–23) relative to 968 breast cancer deaths averted by early detection from screening. Women exposed at the 95th percentile were projected to develop 246 radiation-induced breast cancers leading to 32 deaths per 100,000 women. Women with large breasts requiring extra views for complete breast examination (8% of population) were projected to have higher radiation-induced breast cancer incidence and mortality (266 cancers, 35 deaths per 100,000 women), compared to women with small or average breasts (113 cancers, 15 deaths per 100,000 women). Biennial screening starting at age 50 reduced risk of radiation-induced cancers 5-fold. Limitations We were unable to estimate years of life lost from radiation-induced breast cancer. Conclusions Radiation-induced breast cancer incidence and mortality from digital mammography screening are impacted by dose variability from screening and resultant diagnostic work-up, initiation age, and screening frequency. Women with large breasts may be at higher risk of radiation-induced breast cancer; however, the benefits of screening outweigh these risks. PMID:26756460

Association between genome-wide copy number variation and arsenic-induced skin lesions: a prospective study.

PubMed

Kibriya, Muhammad G; Jasmine, Farzana; Parvez, Faruque; Argos, Maria; Roy, Shantanu; Paul-Brutus, Rachelle; Islam, Tariqul; Ahmed, Alauddin; Rakibuz-Zaman, Muhammad; Shinkle, Justin; Slavkovich, Vesna; Graziano, Joseph H; Ahsan, Habibul

2017-07-18

Exposure to arsenic in drinking water is a global health problem and arsenic-induced skin lesions are hallmark of chronic arsenic toxicity. We and others have reported germline genetic variations as risk factors for such skin lesions. The role of copy number variation (CNV) in the germline DNA in this regard is unknown. From a large prospectively followed-up cohort, exposed to arsenic, we randomly selected 2171 subjects without arsenic-induced skin lesions at enrollment and genotyped their whole blood DNA samples on Illumina Cyto12v2.1 SNP chips to generate DNA copy number. Participants were followed up every 2 years for a total of 8 years, especially for the development of skin lesions. In Cox regression models, each CNV segment was used as a predictor, accounting for other potential covariates, for incidence of skin lesions. The presence of genomic deletion(s) in a number of genes (OR5J2, GOLGA6L7P, APBA2, GALNTL5, VN1R31P, PHKG1P2, SGCZ, ZNF658) and lincRNA genes (RP11-76I14.1, CTC-535 M15.2, RP11-73B2.2) were associated with higher risk [HR between 1.67 (CI 1.3-2.1) and 2.15 (CI 1.5-2.9) for different CNVs] for development of skin lesions independent of gender, age, and arsenic exposure. Some deletions had stronger effect in a specific gender (ZNF658 in males, SGCZ in females) and some had stronger effect in higher arsenic exposure (lincRNA CTD-3179P9.1) suggesting a possible gene-environment interaction. This first genome-wide CNV study in a prospectively followed-up large cohort, exposed to arsenic, suggests that DNA deletion in several genes and lincRNA genes may predispose an individual to a higher risk of development of arsenic-induced skin lesions.

Reduced lattice thermal conductivity of Fe-bearing bridgmanite in Earth's deep mantle: Reduced Conductivity of Fe-Bridgmanite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hsieh, Wen-Pin; Deschamps, Frédéric; Okuchi, Takuo

Complex seismic, thermal, and chemical features have been reported in Earth's lowermost mantle. In particular, possible iron enrichments in the large low shear-wave velocity provinces (LLSVPs) could influence thermal transport properties of the constituting minerals in this region, altering the lower mantle dynamics and heat flux across core-mantle boundary (CMB). Thermal conductivity of bridgmanite is expected to partially control the thermal evolution and dynamics of Earth's lower mantle. Importantly, the pressure-induced lattice distortion and iron spin and valence states in bridgmanite could affect its lattice thermal conductivity, but these effects remain largely unknown. Here we precisely measured the lattice thermalmore » conductivity of Fe-bearing bridgmanite to 120 GPa using optical pump-probe spectroscopy. The conductivity of Fe-bearing bridgmanite increases monotonically with pressure but drops significantly around 45 GPa due to pressure-induced lattice distortion on iron sites. Our findings indicate that lattice thermal conductivity at lowermost mantle conditions is twice smaller than previously thought. The decrease in the thermal conductivity of bridgmanite in mid-lower mantle and below would promote mantle flow against a potential viscosity barrier, facilitating slabs crossing over the 1000 km depth. Modeling of our results applied to LLSVPs shows that variations in iron and bridgmanite fractions induce a significant thermal conductivity decrease, which would enhance internal convective flow. Our CMB heat flux modeling indicates that while heat flux variations are dominated by thermal effects, variations in thermal conductivity also play a significant role. The CMB heat flux map we obtained is substantially different from those assumed so far, which may influence our understanding of the geodynamo.« less

Reduced Lattice Thermal Conductivity of Fe-bearing Bridgmanite in Earth's Deep Mantle

NASA Astrophysics Data System (ADS)

Hsieh, W. P.; Deschamps, F.; Okuchi, T.; Lin, J. F.

2017-12-01

Complex seismic and thermo-chemical features have been revealed in Earth's lowermost mantle. Particularly, possible iron enrichments in the large low shear-wave velocity provinces (LLSVPs) could influence thermal transport properties of the constituting minerals in this region, which, in turn, may alter the lower mantle dynamics and heat flux across core-mantle boundary (CMB). Thermal conductivity of bridgmanite is expected to partially control the thermal evolution and dynamics of Earth's lower mantle. Importantly, the pressure-induced lattice distortion in bridgmanite could affect its lattice thermal conductivity, but this effect remains largely unknown. Here we report our measurements of the lattice thermal conductivity of Fe-bearing and (Fe,Al)-bearing bridgmanites to 120 GPa using optical pump-probe spectroscopy. The thermal conductivity of Fe-bearing bridgmanite increases monotonically with pressure, but drops significantly around 45 GPa presumably due to pressure-induced lattice distortion on iron sites. Our findings indicate that lattice thermal conductivity at lowermost mantle conditions is twice smaller than previously thought. The decrease in the thermal conductivity of bridgmanite in mid-lower mantle and below would promote mantle flow against a potential viscosity barrier, facilitating slabs crossing over the 1000-km depth. Modeling of our results applied to the LLSVPs shows that variations in iron and bridgmanite fractions induce a significant thermal conductivity decrease, which would enhance internal convective flow. Our CMB heat flux modeling indicates that, while heat flux variations are dominated by thermal effects, variations in thermal conductivity also play a significant role. The CMB heat flux map we obtained is substantially different from those assumed so far, which may influence our understanding of the geodynamo.

Measurement and Simulation of the Variation in Proton-Induced Energy Deposition in Large Silicon Diode Arrays

NASA Technical Reports Server (NTRS)

Howe, Christina L.; Weller, Robert A.; Reed, Robert A.; Sierawski, Brian D.; Marshall, Paul W.; Marshall, Cheryl J.; Mendenhall, Marcus H.; Schrimpf, Ronald D.

2007-01-01

The proton induced charge deposition in a well characterized silicon P-i-N focal plane array is analyzed with Monte Carlo based simulations. These simulations include all physical processes, together with pile up, to accurately describe the experimental data. Simulation results reveal important high energy events not easily detected through experiment due to low statistics. The effects of each physical mechanism on the device response is shown for a single proton energy as well as a full proton space flux.

Global Climate Forcing from Albedo Change Caused by Large-scale Deforestation and Reforestation: Quantification and Attribution of Geographic Variation

NASA Technical Reports Server (NTRS)

Gao, Feng; Ghimire, Bardan; Jiao, Tong; Williams, Christopher A.; Masek, Jeffrey; Schaaf, Crystal

2017-01-01

Large-scale deforestation and reforestation have contributed substantially to historical and contemporary global climate change in part through albedo-induced radiative forcing, with meaningful implications for forest management aiming to mitigate climate change. Associated warming or cooling varies widely across the globe due to a range of factors including forest type, snow cover, and insolation, but resulting geographic variation remain spoorly described and has been largely based on model assessments. This study provides an observation-based approach to quantify local and global radiative forcings from large-scale deforestation and reforestation and further examines mechanisms that result in the spatial heterogeneity of radiative forcing. We incorporate a new spatially and temporally explicit land cover-specific albedo product derived from Moderate Resolution Imaging Spectroradiometer with a historical land use data set (Land Use Harmonization product). Spatial variation in radiative forcing was attributed to four mechanisms, including the change in snow-covered albedo, change in snow-free albedo, snow cover fraction, and incoming solar radiation. We find an albedo-only radiative forcing (RF) of -0.819 W m(exp -2) if year 2000 forests were completely deforested and converted to croplands. Albedo RF from global reforestation of present-day croplands to recover year 1700 forests is estimated to be 0.161 W m)exp -2). Snow-cover fraction is identified as the primary factor in determining the spatial variation of radiative forcing in winter, while the magnitude of the change in snow-free albedo is the primary factor determining variations in summertime RF. Findings reinforce the notion that, for conifers at the snowier high latitudes, albedo RF diminishes the warming from forest loss and the cooling from forest gain more so than for other forest types, latitudes, and climate settings.

Linking lowermost mantle structure, core-mantle boundary heat flux and mantle plume formation

NASA Astrophysics Data System (ADS)

Li, Mingming; Zhong, Shijie; Olson, Peter

2018-04-01

The dynamics of Earth's lowermost mantle exert significant control on the formation of mantle plumes and the core-mantle boundary (CMB) heat flux. However, it is not clear if and how the variation of CMB heat flux and mantle plume activity are related. Here, we perform geodynamic model experiments that show how temporal variations in CMB heat flux and pulses of mantle plumes are related to morphologic changes of the thermochemical piles of large-scale compositional heterogeneities in Earth's lowermost mantle, represented by the large low shear velocity provinces (LLSVPs). We find good correlation between the morphologic changes of the thermochemical piles and the time variation of CMB heat flux. The morphology of the thermochemical piles is significantly altered during the initiation and ascent of strong mantle plumes, and the changes in pile morphology cause variations in the local and the total CMB heat flux. Our modeling results indicate that plume-induced episodic variations of CMB heat flux link geomagnetic superchrons to pulses of surface volcanism, although the relative timing of these two phenomena remains problematic. We also find that the density distribution in thermochemical piles is heterogeneous, and that the piles are denser on average than the surrounding mantle when both thermal and chemical effects are included.

Understanding Madden-Julian-Induced sea surface temperature variations in the North Western Australian Basin

NASA Astrophysics Data System (ADS)

Vialard, J.; Drushka, K.; Bellenger, H.; Lengaigne, M.; Pous, S.; Duvel, J. P.

2013-12-01

The strongest large-scale intraseasonal (30-110 day) sea surface temperature (SST) variations in austral summer in the tropics are found in the eastern Indian Ocean between Australia and Indonesia (North-Western Australian Basin, or NWAB). TMI and Argo observations indicate that the temperature signal (std. ~0.4 °C) is most prominent within the top 20 m. This temperature signal appears as a standing oscillation with a 40-50 day timescale within the NWAB, associated with ~40 Wm-2 net heat fluxes (primarily shortwave and latent) and ~0.02 Nm-2 wind stress perturbations. This signal is largely related to the Madden-Julian Oscillation. A slab ocean model with climatological observed mixed-layer depth and an ocean general circulation model both accurately reproduce the observed intraseasonal SST oscillations in the NWAB. Both indicate that most of the intraseasonal SST variations in the NWAB in austral winter are related to surface heat flux forcing, and that intraseasonal SST variations are largest in austral summer because the mixed-layer is shallow (~20 m) and thus more responsive during that season. The general circulation model indicates that entrainment cooling plays little role in intraseasonal SST variations. The larger intraseasonal SST variations in the NWAB as compared to the widely-studied thermocline-ridge of the Indian Ocean region is explained by the larger convective and air-sea heat flux perturbations in the NWAB.

Effect of nonzero surface admittance on receptivity and stability of compressible boundary layer

NASA Technical Reports Server (NTRS)

Choudhari, Meelan

1994-01-01

The effect of small-amplitude short-scale variations in surface admittance on the acoustic receptivity and stability of two-dimensional compressible boundary layers is examined. In the linearized limit, the two problems are shown to be related both physically and mathematically. This connection between the two problems is used, in conjunction with some previously reported receptivity results, to infer the modification of stability properties due to surface permeability. Numerical calculations are carried out for a self-similar flat-plate boundary layer at subsonic and low supersonic speeds. Variations in mean suction velocity at the perforated admittance surface can also induce receptivity to an acoustic wave. For a subsonic boundary layer, the dependence of admittance-induced receptivity on the acoustic-wave orientation is significantly different from that of the receptivity produced via mean suction variation. The admittance-induced receptivity is generally independent of the angle of acoustic incidence, except in a relatively narrow range of upstream-traveling waves for which the receptivity becomes weaker. However, this range of angles is precisely that for which the suction-induced receptivity tends to be large. At supersonic Mach numbers, the admittance-induced receptivity to slow acoustic models is relatively weaker than that in the case of the fast acoustic modes. We also find that purely real values for the surface admittance tend to have a destabilizing effect on the evolution of an instability wave over a slightly permeable surface. The limits on the validity of the linearized approximation are also assessed in one specific case.

Roughness topographical effects on mean momentum and stress budgets in developed turbulent channel flows

NASA Astrophysics Data System (ADS)

Aghaei Jouybari, Mostafa; Yuan, Junlin

2017-11-01

Direct numerical simulations of turbulent channel flows are carried out over two surfaces: a synthesized sand-grain surface and a realistic turbine roughness that is characterized by more prominent large-scale surface features. To separate the effects of wall-normal variation of the roughness area fraction from the (true) variation of flow statistics, the governing equations are area-averaged using intrinsic averaging, contrary to the usually practice based on the total area (i.e., superficial averaging). Additional terms appear in the mean-momentum equation resulted from the wall-normal variation of the solid fraction and play a role in the near-wall balance. Results from surfaces with a step solidity function (e.g., cubes) will also be discussed. Compared to the sand grains, the turbine surface generates stronger form-induced fluctuations, despite weaker dispersive shear stress. This is associated with more significant form-induced productions (comparable to shear production) in Reynolds stress budgets, weaker pressure work, and, consequently, more anisotropic redistribution of turbulent kinetic energy in the roughness sublayer, which potentially leads to different turbulent responses between the two surfaces in non-equilibrium flows.

Multi-technique approach for deriving a VLBI signal extra-path variation model induced by gravity: the example of Medicina

NASA Astrophysics Data System (ADS)

Sarti, P.; Abbondanza, C.; Negusini, M.; Vittuari, L.

2009-09-01

During the measurement sessions gravity might induce significant deformations in large VLBI telescopes. If neglected or mismodelled, these deformations might bias the phase of the incoming signal thus corrupting the estimate of some crucial geodetic parameters (e.g. the height component of VLBI Reference Point). This paper describes a multi-technique approach implemented for measuring and quantifying the gravity-dependent deformations experienced by the 32-m diameter VLBI antenna of Medicina (Northern Italy). Such an approach integrates three different methods: Terrestrial Triangulations and Trilaterations (TTT), Laser Scanning (LS) and a Finite Element Model (FEM) of the antenna. The combination of the observations performed with these methods allows to accurately define an elevation-dependent model of the signal path variation which appears to be, for the Medicina telescope, non negligible. In the range [0,90] deg the signal path increases monotonically by almost 2 cm. The effect of such a variation has not been introduced in actual VLBI analysis yet; nevertheless this is the task we are going to pursue in the very next future.

Astronomical variation experiments with a Mars general circulation model

NASA Technical Reports Server (NTRS)

Pollack, J. B.; Haberle, R. M.; Murphy, J. R.; Schaeffer, J.; Lee, H.

1992-01-01

In time scales of a hundred thousand to a million years, the eccentricity of Mars orbit varies in a quasi-periodic manner between extremes as large as 0.14 and as small as 0 and the tilt of its axis of rotation with respect to the orbit normal also varies quasi-periodically between extremes as large as 35 deg and as small as 15 deg. In addition, the orientation of the axis precesses on comparable time scales. These astronomical variations are much more extreme than those experienced by the Earth. These variations are thought to have strongly modulated the seasonal cycles of dust, carbon dioxide, and water. One manifestation of the induced quasiperiodic climate changes may be the layered terrain of the polar regions, with individual layers perhaps recording variations in the absolute and/or relative deposition rates of dust and water in the polar regions, most likely in association with the winter time deposition of carbon dioxide ice. In an attempt to understand the manner in which atmospheric temperatures and winds respond to the astronomical forcings, we have initiated a series of numerical experiments with the NASA/Ames general circulation model of the Martian Atmosphere.

Coriolis effects on nonlinear oscillations of rotating cylinders and rings

NASA Technical Reports Server (NTRS)

Padovan, J.

1976-01-01

The effects which moderately large deflections have on the frequency spectrum of rotating rings and cylinders are considered. To develop the requisite solution, a variationally constrained version of the Lindstedt-Poincare procedure is employed. Based on the solution developed, in addition to considering the effects of displacement induced nonlinearity, the role of Coriolis forces is also given special consideration.

Development of flow separation control system to reduce the vibration of wind turbine blades

NASA Astrophysics Data System (ADS)

Kim, Ho-Young; Kim, Ho-Hyun; Han, Jong-Seob; Han, Jae-Hung

2017-04-01

The size of wind turbine blade has been continuously increased. Large-scale wind turbine blades induce loud noise, vibration; and maintenance difficulty is also increased. It causes the eventual increases of the cost of energy. The vibration of wind turbine blade is caused by several reasons such as a blade rotation, tower shadow, wind shear, and flow separation of a wind turbine blade. This wind speed variation changes in local angle of attack of the blades and create the vibration. The variation of local angle of attack influences the lift coefficient and causes the large change of the lift. In this study, we focus on the lift coefficient control using a flow control device to reduce the vibration. DU35-A15 airfoil was employed as baseline model. A plasma actuator was installed to generate the upwind jet in order to control the lift coefficient. Wind tunnel experiment was performed to demonstrate of the performance of the plasma actuator. The results show the plasma actuator can induce the flow separation compared with the baseline model. In addition, the actuator can delay the flow separation depending on the input AC frequency with the same actuator configuration.

Handling qualities of large flexible control-configured aircraft

NASA Technical Reports Server (NTRS)

Swaim, R. L.

1980-01-01

The effects on handling qualities of low frequency symmetric elastic mode interaction with the rigid body dynamics of a large flexible aircraft was analyzed by use of a mathematical pilot modeling computer simulation. An extension of the optimal control model for a human pilot was made so that the mode interaction effects on the pilot's control task could be assessed. Pilot ratings were determined for a longitudinal tracking task with parametric variations in the undamped natural frequencies of the two lowest frequency symmetric elastic modes made to induce varying amounts of mode interaction. Relating numerical performance index values associated with the frequency variations used in several dynamic cases, to a numerical Cooper-Harper pilot rating has proved successful in discriminating when the mathematical pilot can or cannot separate rigid from elastic response in the tracking task.

Reducing variation in a rabbit vaccine safety study with particular emphasis on housing conditions and handling.

PubMed

Verwer, Cynthia M; van der Ark, Arno; van Amerongen, Geert; van den Bos, Ruud; Hendriksen, Coenraad F M

2009-04-01

This paper describes the results of a study of the effects of modified housing conditions, conditioning and habituation on humans using a rabbit model for monitoring whole-cell pertussis vaccine (pWCV)-induced adverse effects. The study has been performed with reference to previous vaccine safety studies of pWCV in rabbits in which results were difficult to interpret due to the large variation in experimental outcome, especially in the key parameter deep-body temperature (T(b)). Certain stressful laboratory conditions, as well as procedures involving humans, e.g. blood sampling, inoculation and cage-cleaning, were hypothesized to cause this large variation. The results of this study show that under modified housing conditions rabbits have normal circadian body temperatures. This allowed discrimination of pWCV-induced adverse effects in which handled rabbits tended to show a dose-related increase in temperature after inoculation with little variance, whereas non-handled rabbits did not. Effects of experimental and routine procedures on body temperature were significantly reduced under modified conditions and were within the normal T(b) range. Handled animals reacted less strongly and with less variance to experimental procedures, such as blood sampling, injection and cage-cleaning, than non-handled rabbits. Overall, handling had a positive effect on the behaviour of the animals. Data show that the housing modifications have provided a more robust model for monitoring pWCV adverse effects. Furthermore, conditioning and habituation of rabbits to humans reduce the variation in experimental outcome, which might allow for a reduction in the number of animals used. In addition, this also reduces distress and thus contributes to refining this animal model.

Handling Qualities of Large Flexible Aircraft. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Poopaka, S.

1980-01-01

The effects on handling qualities of elastic modes interaction with the rigid body dynamics of a large flexible aircraft are studied by a mathematical computer simulation. An analytical method to predict the pilot ratings when there is a severe modes interactions is developed. This is done by extending the optimal control model of the human pilot response to include the mode decomposition mechanism into the model. The handling qualities are determined for a longitudinal tracking task using a large flexible aircraft with parametric variations in the undamped natural frequencies of the two lowest frequency, symmetric elastic modes made to induce varying amounts of mode interaction.

Seismicity Induced by Groundwater Recharge at Mt. Hood, Oregon, and its Implications for Hydrogeologic Properties.

NASA Astrophysics Data System (ADS)

Saar, M. O.; Manga, M.

2002-12-01

Earthquakes induced by human-caused changes in fluid pressure have been documented for many years. Examples include seismicity induced by filling reservoirs and by fluid injection or extraction. Less well-documented are seismic events that potentially are triggered by natural variations in groundwater recharge rates (e.g., Wolf et al., BSSA, 1997; Jimenez and Garcia-Fernandez, JVGR, 2000; Audin et al., GRL, 2002). Large groundwater recharge rates can occur in Volcanic Arcs such as the Oregon Cascades where annual precipitation is > 2 m of which > 50 % infiltrates the ground mostly during snowmelt in spring. As a result, infiltration rates of > 1 m per year concentrated during a few months can occur. Near-surface porosities are about 5-10 %. Thus, groundwater levels may fluctuate annually by about 10-20 m resulting in seasonal pore fluid pressure variations of about 1-2 x 105 Pa. Such large-amplitude, narrow-duration fluid pressure signals may allow investigation of seismicity induced by pore fluid pressure diffusion without the influence of engineered systems such as reservoirs. This kind of in-situ study of natural systems over large representative elementary volumes may allow determination of hydrologic parameters at spatial and temporal scales that are relevant for regional hydrogeology. Furthermore, natural hydrologic triggering of earthquakes that persist for decades provides insight into the state of stress in the crust and suggest long-term near-critical failure conditions. Here, we approximate the temporal variations in groundwater recharge with discharge in runoff-dominated streams at high elevations that show a peak in discharge during snow melt. Seismicity is evaluated as time series of daily number of earthquakes and seismic moments. Both stream discharge and seismicity are compared at equivalent frequency bands by applying segmented least-squares polynomial fits to the data. We find statistically significant correlation between groundwater recharge and seismicity at Mt. Hood, Oregon. We can use the time lag of about 120 days between the two records to estimate the regional hydraulic diffusivity (1 m2/s) and other hydrogeologic parameters (permeability ≈ 10-13 m2, vertical matrix compressibility ≈ 10-10 m2/N). These values are comparable with our results from coupled heat and groundwater flow studies that are based on bore hole temperature data at Mt. Hood.

The modelling of dispersion in 2-D tidal flow over an uneven bed

NASA Astrophysics Data System (ADS)

Kalkwijk, Jan P. Th.

This paper deals with the effective mixing by topographic induced velocity variations in 2-D tidal flow. This type of mixing is characterized by tidally-averaged dispersion coefficients, which depend on the magnitude of the depth variations with respect to a mean depth, the velocity variations and the basic dispersion coefficients. The analysis is principally based on a Taylor type approximation (large clouds, small concentration variations) of the 2-D advection diffusion equation and a 2-D velocity field that behaves harmonically both in time and in space. Neglecting transient phenomena and applying time and space averaging the effective dispersion coefficients can be derived. Under certain circumstances it is possible to relate the velocity variations to the depth variations, so that finally effective dispersion coefficients can be determined using the power spectrum of the depth variations. In a special paragraph attention is paid to the modelling of sub-grid mixing in case of numerical integration of the advection-diffusion equation. It appears that the dispersion coefficients taking account of the sub-grid mixing are not only determined by the velocity variations within a certain grid cell, but also by the velocity variations at a larger scale.

The imprint of surface fluxes and transport on variations in total column carbon dioxide

NASA Astrophysics Data System (ADS)

Keppel-Aleks, G.; Wennberg, P. O.; Washenfelder, R. A.; Wunch, D.; Schneider, T.; Toon, G. C.; Andres, R. J.; Blavier, J.-F.; Connor, B.; Davis, K. J.; Desai, A. R.; Messerschmidt, J.; Notholt, J.; Roehl, C. M.; Sherlock, V.; Stephens, B. B.; Vay, S. A.; Wofsy, S. C.

2011-07-01

New observations of the vertically integrated CO2 mixing ratio, ⟨CO2⟩, from ground-based remote sensing show that variations in ⟨CO2⟩ are primarily determined by large-scale flux patterns. They therefore provide fundamentally different information than observations made within the boundary layer, which reflect the combined influence of large scale and local fluxes. Observations of both ⟨CO2⟩ and CO2 concentrations in the free troposphere show that large-scale spatial gradients induce synoptic-scale temporal variations in ⟨CO2⟩ in the Northern Hemisphere midlatitudes through horizontal advection. Rather than obscure the signature of surface fluxes on atmospheric CO2, these synoptic-scale variations provide useful information that can be used to reveal the meridional flux distribution. We estimate the meridional gradient in ⟨CO2⟩ from covariations in ⟨CO2⟩ and potential temperature, θ, a dynamical tracer, on synoptic timescales to evaluate surface flux estimates commonly used in carbon cycle models. We find that Carnegie Ames Stanford Approach (CASA) biospheric fluxes underestimate both the ⟨CO2⟩ seasonal cycle amplitude throughout the Northern Hemisphere midlatitudes as well as the meridional gradient during the growing season. Simulations using CASA net ecosystem exchange (NEE) with increased and phase-shifted boreal fluxes better reflect the observations. Our simulations suggest that boreal growing season NEE (between 45-65° N) is underestimated by ~40 % in CASA. We describe the implications for this large seasonal exchange on inference of the net Northern Hemisphere terrestrial carbon sink.

The imprint of surface fluxes and transport on variations in total column carbon dioxide

NASA Astrophysics Data System (ADS)

Keppel-Aleks, G.; Wennberg, P. O.; Washenfelder, R. A.; Wunch, D.; Schneider, T.; Toon, G. C.; Andres, R. J.; Blavier, J.-F.; Connor, B.; Davis, K. J.; Desai, A. R.; Messerschmidt, J.; Notholt, J.; Roehl, C. M.; Sherlock, V.; Stephens, B. B.; Vay, S. A.; Wofsy, S. C.

2012-03-01

New observations of the vertically integrated CO2 mixing ratio, ⟨CO2⟩, from ground-based remote sensing show that variations in CO2⟩ are primarily determined by large-scale flux patterns. They therefore provide fundamentally different information than observations made within the boundary layer, which reflect the combined influence of large-scale and local fluxes. Observations of both ⟨CO2⟩ and CO2 concentrations in the free troposphere show that large-scale spatial gradients induce synoptic-scale temporal variations in ⟨CO2⟩ in the Northern Hemisphere midlatitudes through horizontal advection. Rather than obscure the signature of surface fluxes on atmospheric CO2, these synoptic-scale variations provide useful information that can be used to reveal the meridional flux distribution. We estimate the meridional gradient in ⟨CO2⟩ from covariations in ⟨CO2⟩ and potential temperature, θ, a dynamical tracer, on synoptic timescales to evaluate surface flux estimates commonly used in carbon cycle models. We find that simulations using Carnegie Ames Stanford Approach (CASA) biospheric fluxes underestimate both the ⟨CO2⟩ seasonal cycle amplitude throughout the Northern Hemisphere midlatitudes and the meridional gradient during the growing season. Simulations using CASA net ecosystem exchange (NEE) with increased and phase-shifted boreal fluxes better fit the observations. Our simulations suggest that climatological mean CASA fluxes underestimate boreal growing season NEE (between 45-65° N) by ~40%. We describe the implications for this large seasonal exchange on inference of the net Northern Hemisphere terrestrial carbon sink.

Genetic variation in insulin-induced kinase signaling

PubMed Central

Wang, Isabel Xiaorong; Ramrattan, Girish; Cheung, Vivian G

2015-01-01

Individual differences in sensitivity to insulin contribute to disease susceptibility including diabetes and metabolic syndrome. Cellular responses to insulin are well studied. However, which steps in these response pathways differ across individuals remains largely unknown. Such knowledge is needed to guide more precise therapeutic interventions. Here, we studied insulin response and found extensive individual variation in the activation of key signaling factors, including ERK whose induction differs by more than 20-fold among our subjects. This variation in kinase activity is propagated to differences in downstream gene expression response to insulin. By genetic analysis, we identified cis-acting DNA variants that influence signaling response, which in turn affects downstream changes in gene expression and cellular phenotypes, such as protein translation and cell proliferation. These findings show that polymorphic differences in signal transduction contribute to individual variation in insulin response, and suggest kinase modulators as promising therapeutics for diseases characterized by insulin resistance. PMID:26202599

Analysis of natural variation in bermudagrass (Cynodon dactylon) reveals physiological responses underlying drought tolerance.

PubMed

Shi, Haitao; Wang, Yanping; Cheng, Zhangmin; Ye, Tiantian; Chan, Zhulong

2012-01-01

Bermudagrass (Cynodon dactylon) is a widely used warm-season turfgrass and one of the most drought tolerant species. Dissecting the natural variation in drought tolerance and physiological responses will bring us powerful basis and novel insight for plant breeding. In the present study, we evaluated the natural variation of drought tolerance among nine bermudagrass varieties by measuring physiological responses after drought stress treatment through withholding water. Three groups differing in drought tolerance were identified, including two tolerant, five moderately tolerant and two susceptible varieties. Under drought stress condition, drought sensitive variety (Yukon) showed relative higher water loss, more severe cell membrane damage (EL), and more accumulation of hydrogen peroxide (H₂O₂) and malondialdehyde (MDA), while drought tolerant variety (Tifgreen) exhibited significantly higher antioxidant enzymes activities. Further results indicated that drought induced cell injury in different varieties (Yukon, SR9554 and Tifgreen) exhibited liner correlation with leaf water content (LWC), H₂O₂ content, MDA content and antioxidant enzyme activities. Additionally, Tifgreen plants had significantly higher levels of osmolytes (proline level and soluble sugars) when compared with Yukon and SR9554 under drought stress condition. Taken together, our results indicated that natural variation of drought stress tolerance in bermudagrass varieties might be largely related to the induced changes of water status, osmolyte accumulation and antioxidant defense system.

On the effect of standard PFEM remeshing on volume conservation in free-surface fluid flow problems

NASA Astrophysics Data System (ADS)

Franci, Alessandro; Cremonesi, Massimiliano

2017-07-01

The aim of this work is to analyze the remeshing procedure used in the particle finite element method (PFEM) and to investigate how this operation may affect the numerical results. The PFEM remeshing algorithm combines the Delaunay triangulation and the Alpha Shape method to guarantee a good quality of the Lagrangian mesh also in large deformation processes. However, this strategy may lead to local variations of the topology that may cause an artificial change of the global volume. The issue of volume conservation is here studied in detail. An accurate description of all the situations that may induce a volume variation during the PFEM regeneration of the mesh is provided. Moreover, the crucial role of the parameter α used in the Alpha Shape method is highlighted and a range of values of α for which the differences between the numerical results are negligible, is found. Furthermore, it is shown that the variation of volume induced by the remeshing reduces by refining the mesh. This check of convergence is of paramount importance for the reliability of the PFEM. The study is carried out for 2D free-surface fluid dynamics problems, however the conclusions can be extended to 3D and to all those problems characterized by significant variations of internal and external boundaries.

Effect of ship locking on sediment oxygen uptake in impounded rivers

NASA Astrophysics Data System (ADS)

Lorke, A.; McGinnis, D. F.; Maeck, A.; Fischer, H.

2012-12-01

In the majority of large river systems, flow is regulated and/or otherwise affected by operational and management activities, such as ship locking. The effect of lock operation on sediment-water oxygen fluxes was studied within a 12.9 km long impoundment at the Saar River (Germany) using eddy-correlation flux measurements. The continuous observations cover a time period of nearly 5 days and 39 individual locking events. Ship locking is associated with the generation of surges propagating back and forth through the impoundment which causes strong variations of near-bed current velocity and turbulence. These wave-induced flow variations cause variations in sediment-water oxygen fluxes. While the mean flux during time periods without lock operation was 0.5 ± 0.1 g m-2 d-1, it increased by about a factor of 2 to 1.0 ± 0.5 g m-2 d-1within time periods with ship locking. Following the daily schedule of lock operations, fluxes are predominantly enhanced during daytime and follow a pronounced diurnal rhythm. The driving force for the increased flux is the enhancement of diffusive transport across the sediment-water interface by bottom-boundary layer turbulence and perhaps resuspension. Additional means by which the oxygen budget of the impoundment is affected by lock-induced flow variations are discussed.

Application of Satellite Solar-Induced Chlorophyll Fluorescence to Understanding Large-Scale Variations in Vegetation Phenology and Function Over Northern High Latitude Forests

NASA Technical Reports Server (NTRS)

Jeong, Su-Jong; Schimel, David; Frankenberg, Christian; Drewry, Darren T.; Fisher, Joshua B.; Verma, Manish; Berry, Joseph A.; Lee, Jung-Eun; Joiner, Joanna

2016-01-01

This study evaluates the large-scale seasonal phenology and physiology of vegetation over northern high latitude forests (40 deg - 55 deg N) during spring and fall by using remote sensing of solar-induced chlorophyll fluorescence (SIF), normalized difference vegetation index (NDVI) and observation-based estimate of gross primary productivity (GPP) from 2009 to 2011. Based on GPP phenology estimation in GPP, the growing season determined by SIF time-series is shorter in length than the growing season length determined solely using NDVI. This is mainly due to the extended period of high NDVI values, as compared to SIF, by about 46 days (+/-11 days), indicating a large-scale seasonal decoupling of physiological activity and changes in greenness in the fall. In addition to phenological timing, mean seasonal NDVI and SIF have different responses to temperature changes throughout the growing season. We observed that both NDVI and SIF linearly increased with temperature increases throughout the spring. However, in the fall, although NDVI linearly responded to temperature increases, SIF and GPP did not linearly increase with temperature increases, implying a seasonal hysteresis of SIF and GPP in response to temperature changes across boreal ecosystems throughout their growing season. Seasonal hysteresis of vegetation at large-scales is consistent with the known phenomena that light limits boreal forest ecosystem productivity in the fall. Our results suggest that continuing measurements from satellite remote sensing of both SIF and NDVI can help to understand the differences between, and information carried by, seasonal variations vegetation structure and greenness and physiology at large-scales across the critical boreal regions.

Phase transitions triggered by quantum fluctuations in the inflationary universe

NASA Technical Reports Server (NTRS)

Nagasawa, Michiyasu; Yokoyama, Junichi

1991-01-01

The dynamics of a second-order phase transition during inflation, which is induced by time-variation of spacetime curvature, is studied as a natural mechanism to produce topological defects of typical grand unification scales such as cosmic strings or global textures. It is shown that their distribution is almost scale-invariant with small- and large-scale cutoffs. Also discussed is how these cutoffs are given.

Large Deployable Reflector (LDR) thermal characteristics

NASA Technical Reports Server (NTRS)

Miyake, R. N.; Wu, Y. C.

1988-01-01

The thermal support group, which is part of the lightweight composite reflector panel program, developed thermal test and analysis evaluation tools necessary to support the integrated interdisciplinary analysis (IIDA) capability. A detailed thermal mathematical model and a simplified spacecraft thermal math model were written. These models determine the orbital temperature level and variation, and the thermally induced gradients through and across a panel, for inclusion in the IIDA.

Tissue culture-induced genetic and epigenetic variation in triticale (× Triticosecale spp. Wittmack ex A. Camus 1927) regenerants.

PubMed

Machczyńska, Joanna; Zimny, Janusz; Bednarek, Piotr Tomasz

2015-10-01

Plant regeneration via in vitro culture can induce genetic and epigenetic variation; however, the extent of such changes in triticale is not yet understood. In the present study, metAFLP, a variation of methylation-sensitive amplified fragment length polymorphism analysis, was used to investigate tissue culture-induced variation in triticale regenerants derived from four distinct genotypes using androgenesis and somatic embryogenesis. The metAFLP technique enabled identification of both sequence and DNA methylation pattern changes in a single experiment. Moreover, it was possible to quantify subtle effects such as sequence variation, demethylation, and de novo methylation, which affected 19, 5.5, 4.5% of sites, respectively. Comparison of variation in different genotypes and with different in vitro regeneration approaches demonstrated that both the culture technique and genetic background of donor plants affected tissue culture-induced variation. The results showed that the metAFLP approach could be used for quantification of tissue culture-induced variation and provided direct evidence that in vitro plant regeneration could cause genetic and epigenetic variation.

Fiber-Optic Linear Displacement Sensor Based On Matched Interference Filters

NASA Astrophysics Data System (ADS)

Fuhr, Peter L.; Feener, Heidi C.; Spillman, William B.

1990-02-01

A fiber optic linear displacement sensor has been developed in which a pair of matched interference filters are used to encode linear position on a broadband optical signal as relative intensity variations. As the filters are displaced, the optical beam illuminates varying amounts of each filter. Determination of the relative intensities at each filter pairs' passband is based on measurements acquired with matching filters and photodetectors. Source power variation induced errors are minimized by basing determination of linear position on signal Visibility. A theoretical prediction of the sensor's performance is developed and compared with experiments performed in the near IR spectral region using large core multimode optical fiber.

On the receptivity problem for Goertler vortices: Vortex motions induced by wall roughness

NASA Technical Reports Server (NTRS)

Denier, James P.; Hall, Philip; Seddougui, Sharon

1990-01-01

The receptivity problem for Goertler vortices induced by wall roughness is investigated. The roughness is modelled by small amplitude perturbations to the curved wall over which the flow takes place. The amplitude of these perturbations is taken to be sufficiently small for the induced Goertler vortices to be described by linear theory. The roughness is assumed to vary in the spanwise direction on the boundary layer lengthscale, while in the flow direction the corresponding variation is on the lengthscale over which the wall curvature varies. In fact the latter condition can be relaxed to allow for a faster streamwise roughness variation so long as the variation does not become as fast as that in the spanwise direction. The function which describes the roughness is assumed to be such that its spanwise and streamwise dependences can be separated; this enables progress by taking Fourier or Laplace transforms where appropriate. The cases of isolated and distributed roughness elements are investigated and the coupling coefficient which relates the amplitude of the forcing and the induced vortex amplitude is found asymptotically in the small wavelength limit. It is shown that this coefficient is exponentially small in the latter limit so that it is unlikely that this mode can be stimulated directly by wall roughness. The situation at 0(1) wavelengths is quite different and this is investigated numerically for different forcing functions. It is found that an isolated roughness element induces a vortex field which grows within a wedge at a finite distance downstream of the element. However, immediately downstream of the obstacle the disturbed flow produced by the element decays in amplitude. The receptivity problem at larger Goertler numbers appropriate to relatively large wall curvature is discussed in detail.

Noninvasive Optoelectronic Assessment of Induced Sagittal Imbalance Using the Vicon System.

PubMed

Ould-Slimane, Mourad; Latrobe, Charles; Michelin, Paul; Chastan, Nathalie; Dujardin, Franck; Roussignol, Xavier; Gauthé, Rémi

2017-06-01

Spinal diseases often induce gait disorders with multifactorial origins such as lumbar pain, radicular pain, neurologic complications, or spinal deformities. However, radiography does not permit an analysis of spinal dynamics; therefore, sagittal balance dynamics during gait remain largely unexplored. This prospective and controlled pilot study assessed the Vicon system for detecting sagittal spinopelvic imbalance, to determine the correlations between optoelectronic and radiographic parameters. Reversible anterior sagittal imbalance was induced in 24 healthy men using a thoracolumbar corset. Radiographic, optoelectronic, and comparative analyses were conducted. Corset wearing induced significant variations in radiographic parameters indicative of imbalance; the mean C7-tilt and d/D ratio increased by 15° ± 7.4° and 359%, respectively, whereas the mean spinosacral angle decreased by 16.8° ± 8° (all P < 0.001). The Vicon system detected the imbalance; the mean spinal angle increased by 15.4° ± 5.6° (P < 0.01), the mean floor projection of the C7S1 vector (C7'S1') increased by 126.3 ± 51.9 mm (P < 0.001), and the mean C7-T10-S1 angle decreased by 9.8° ± 3° (P < 0.001). Variations in C7'S1' were significantly correlated with d/D ratio (ρ = 0.58; P < 0.05) and C7-tilt (ρ = 0.636; P < 0.05) variations. Corset wearing induced radiographically confirmed anterior sagittal imbalance detected using the Vicon system. Optoelectronic C7'S1' correlated with radiographic C7-tilt and d/D ratio. Copyright © 2017 Elsevier Inc. All rights reserved.

Inter-Diffusion in the Presence of Free Convection

NASA Technical Reports Server (NTRS)

Gupta, Prabhat K.

1999-01-01

Because of their technological importance, establishment of the precise values of interdiffusion coefficients is important in multicomponent fluid systems. Such values are not available because diffusion is influenced by free convection due to compositionally induced density variations. In this project, earth based diffusion experiments are being performed in a viscous fluid system PbO-SiO2 at temperatures between 500-1000 C. This system is chosen because it shows a large variation in density with small changes in composition and is expected to show a large free convection effect. Infinite diffusion couples at different temperatures and times are being studied with different orientations with respect to gravity. Composition fields will be measured using an Electron Microprobe Analyzer and will be compared with the results of a complementary modeling study to extract the values of the true diffusion coefficient from the measured diffusion profiles.

Pressure-gradient-driven nearshore circulation on a beach influenced by a large inlet-tidal shoal system

USGS Publications Warehouse

Shi, F.; Hanes, D.M.; Kirby, J.T.; Erikson, L.; Barnard, P.; Eshleman, J.

2011-01-01

The nearshore circulation induced by a focused pattern of surface gravity waves is studied at a beach adjacent to a major inlet with a large ebb tidal shoal. Using a coupled wave and wave-averaged nearshore circulation model, it is found that the nearshore circulation is significantly affected by the heterogeneous wave patterns caused by wave refraction over the ebb tidal shoal. The model is used to predict waves and currents during field experiments conducted near the mouth of San Francisco Bay and nearby Ocean Beach. The field measurements indicate strong spatial variations in current magnitude and direction and in wave height and direction along Ocean Beach and across the ebb tidal shoal. Numerical simulations suggest that wave refraction over the ebb tidal shoal causes wave focusing toward a narrow region at Ocean Beach. Due to the resulting spatial variation in nearshore wave height, wave-induced setup exhibits a strong alongshore nonuniformity, resulting in a dramatic change in the pressure field compared to a simulation with only tidal forcing. The analysis of momentum balances inside the surf zone shows that, under wave conditions with intensive wave focusing, the alongshore pressure gradient associated with alongshore nonuniform wave setup can be a dominant force driving circulation, inducing heterogeneous alongshore currents. Pressure-gradient- forced alongshore currents can exhibit flow reversals and flow convergence or divergence, in contrast to the uniform alongshore currents typically caused by tides or homogeneous waves.

Spectral relative standard deviation: a practical benchmark in metabolomics.

PubMed

Parsons, Helen M; Ekman, Drew R; Collette, Timothy W; Viant, Mark R

2009-03-01

Metabolomics datasets, by definition, comprise of measurements of large numbers of metabolites. Both technical (analytical) and biological factors will induce variation within these measurements that is not consistent across all metabolites. Consequently, criteria are required to assess the reproducibility of metabolomics datasets that are derived from all the detected metabolites. Here we calculate spectrum-wide relative standard deviations (RSDs; also termed coefficient of variation, CV) for ten metabolomics datasets, spanning a variety of sample types from mammals, fish, invertebrates and a cell line, and display them succinctly as boxplots. We demonstrate multiple applications of spectral RSDs for characterising technical as well as inter-individual biological variation: for optimising metabolite extractions, comparing analytical techniques, investigating matrix effects, and comparing biofluids and tissue extracts from single and multiple species for optimising experimental design. Technical variation within metabolomics datasets, recorded using one- and two-dimensional NMR and mass spectrometry, ranges from 1.6 to 20.6% (reported as the median spectral RSD). Inter-individual biological variation is typically larger, ranging from as low as 7.2% for tissue extracts from laboratory-housed rats to 58.4% for fish plasma. In addition, for some of the datasets we confirm that the spectral RSD values are largely invariant across different spectral processing methods, such as baseline correction, normalisation and binning resolution. In conclusion, we propose spectral RSDs and their median values contained herein as practical benchmarks for metabolomics studies.

Effect of steady and time-harmonic magnetic fields on macrosegragation in alloy solidification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Incropera, F.P.; Prescott, P.J.

Buoyancy-induced convection during the solidification of alloys can contribute significantly to the redistribution of alloy constituents, thereby creating large composition gradients in the final ingot. Termed macrosegregation, the condition diminishes the quality of the casting and, in the extreme, may require that the casting be remelted. The deleterious effects of buoyancy-driven flows may be suppressed through application of an external magnetic field, and in this study the effects of both steady and time-harmonic fields have been considered. For a steady magnetic field, extremely large field strengths would be required to effectively dampen convection patterns that contribute to macrosegregation. However, bymore » reducing spatial variations in temperature and composition, turbulent mixing induced by a time-harmonic field reduces the number and severity of segregates in the final casting.« less

Statistical variability study of random dopant fluctuation on gate-all-around inversion-mode silicon nanowire field-effect transistors

NASA Astrophysics Data System (ADS)

Yoon, Jun-Sik; Rim, Taiuk; Kim, Jungsik; Kim, Kihyun; Baek, Chang-Ki; Jeong, Yoon-Ha

2015-03-01

Random dopant fluctuation effects of gate-all-around inversion-mode silicon nanowire field-effect transistors (FETs) with different diameters and extension lengths are investigated. The nanowire FETs with smaller diameter and longer extension length reduce average values and variations of subthreshold swing and drain-induced barrier lowering, thus improving short channel immunity. Relative variations of the drain currents increase as the diameter decreases because of decreased current drivability from narrower channel cross-sections. Absolute variations of the drain currents decrease critically as the extension length increases due to decreasing the number of arsenic dopants penetrating into the channel region. To understand variability origins of the drain currents, variations of source/drain series resistance and low-field mobility are investigated. All these two parameters affect the variations of the drain currents concurrently. The nanowire FETs having extension lengths sufficient to prevent dopant penetration into the channel regions and maintaining relatively large cross-sections are suggested to achieve suitable short channel immunity and small variations of the drain currents.

Investigations of a Cretaceous limestone with spectral induced polarization and scanning electron microscopy

NASA Astrophysics Data System (ADS)

Johansson, Sara; Sparrenbom, Charlotte; Fiandaca, Gianluca; Lindskog, Anders; Olsson, Per-Ivar; Dahlin, Torleif; Rosqvist, Håkan

2017-02-01

Characterization of varying bedrock properties is a common need in various contexts, ranging from large infrastructure pre-investigations to environmental protection. A direct current resistivity and time domain induced polarization (IP) survey aiming to characterize properties of a Cretaceous limestone was carried out in the Kristianstad basin, Sweden. The time domain IP data was processed with a recently developed method in order to suppress noise from the challenging urban setting in the survey area. The processing also enabled extraction of early decay times resulting in broader spectra of the time decays and inversion for Cole-Cole parameters. The aims of this study is to investigate if large-scale geoelectrical variations as well as small-scale structural and compositional variations exist within the Kristianstad limestone, and to evaluate the usefulness of Cole-Cole inverted IP data in early time ranges for bedrock characterization. The inverted sections showed variations within the limestone that could be caused by variations in texture and composition. Samples from a deep drilling in the Kristianstad basin were investigated with scanning electron microscopy and energy dispersive X-ray spectroscopy, and the results showed that varying amounts of pyrite, glauconite and clay matrix were present at different levels in the limestone. The local high IP anomalies in the limestone could be caused by these minerals otherwise the IP responses were generally weak. There were also differences in the texture of the limestone at different levels, governed by fossil shapes and composition, proportions of calcareous cement and matrix as well as amount of silicate grains. Textural variations may have implications on the variation in Cole-Cole relaxation time and frequency factor. However, more research is needed in order to directly connect microgeometrical properties in limestone to spectral IP responses. The results from this study show that it is possible to recover useable spectral information from early decay times. We also show that under certain conditions (e.g. relatively short relaxation times in the subsurface), it is possible to extract spectral information from time domain IP data measured with on-off times as short as 1 s.

ZebraBeat: a flexible platform for the analysis of the cardiac rate in zebrafish embryos

NASA Astrophysics Data System (ADS)

de Luca, Elisa; Zaccaria, Gian Maria; Hadhoud, Marwa; Rizzo, Giovanna; Ponzini, Raffaele; Morbiducci, Umberto; Santoro, Massimo Mattia

2014-05-01

Heartbeat measurement is important in assesssing cardiac function because variations in heart rhythm can be the cause as well as an effect of hidden pathological heart conditions. Zebrafish (Danio rerio) has emerged as one of the most useful model organisms for cardiac research. Indeed, the zebrafish heart is easily accessible for optical analyses without conducting invasive procedures and shows anatomical similarity to the human heart. In this study, we present a non-invasive, simple, cost-effective process to quantify the heartbeat in embryonic zebrafish. To achieve reproducibility, high throughput and flexibility (i.e., adaptability to any existing confocal microscope system and with a user-friendly interface that can be easily used by researchers), we implemented this method within a software program. We show here that this platform, called ZebraBeat, can successfully detect heart rate variations in embryonic zebrafish at various developmental stages, and it can record cardiac rate fluctuations induced by factors such as temperature and genetic- and chemical-induced alterations. Applications of this methodology may include the screening of chemical libraries affecting heart rhythm and the identification of heart rhythm variations in mutants from large-scale forward genetic screens.

Large Drought-induced Variations in Oak Leaf Volatile Organic Compound Emissions during PINOT NOIR 2012

EPA Pesticide Factsheets

Leaf level oak isoprene emissions and co2/H2O exchange in the Ozarks, USABAGeron.csv is the speciated biomass displayed in Figure 1.Biomass Dry Weights.xlsx is used to convert leaf area to dry leaf biomass and is used in Figure 2.Daly Ozarks leaf ISOP.txt and MOFLUX_Isoprene Summary_refined Tcurve data.xlsx are the leaf isoprene emission rate files shown in Figure 2.Harley Aug12_Chris.xls is the leaf isoprene emission rate file shown in Figure 3.Daly Ozarks leaf.txt is the BVOC emissions file used for Figure 7 and Table 4.Drought IS.txt is the review data given in Table 2.Fig4 Aug10 2012 Harley.txt is shown in Figure 4.Fig 5 Aug14 2012 Harley.txt is shown in Figure 5.Daly Ozarks Leaf.txt is used in Fig 7.Drought IS.txt is used in Fig 8.This dataset is associated with the following publication:Geron , C., R. Daly , P. Harley, R. Rasmussen, R. Seco, A. Guenther, T. Karl, and L. Gu. Large Drought-Induced Variations in Oak Leaf Volatile Organic Compound Emissions during PINOT NOIR 2012. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 146: 8-21, (2016).

Investigation of Characteristics of Large dB/dt for Geomagnetically Induced Currents

NASA Astrophysics Data System (ADS)

Munoz, D.; Ngwira, C.; Damas, M. C.

2016-12-01

When geomagnetically induced currents (GICs) flow through electrical networks, they become a potential threat for electrical power systems. Changes in the geomagnetic field (dB/dt) during severe geomagnetic disturbances are the main sources of GICs. These dB/dt phenomena were studied by selecting 24 strong geomagnetic storms with Dst ≤ - 150 nT. ACE spacecraft solar wind data: flow speed, proton density, By and Bz IMF components of the solar wind were correlated with measurements of the magnetic field detected on ground stations at different latitudes. This article reports characteristics of the solar wind during time intervals of large changes in the horizontal geomagnetic field with a threshold of dB/dt ≥ ± 20 nT/min for the 24 geomagnetic storms. The results of this investigation can help scientists to understand the mechanisms responsible for causing large magnetic field variations in order to predict and mitigate possible large events in the future, which is critical for our society that relies constantly on electricity for livelihood and security. In addition, this ongoing project will continue to investigate electron flux response before, during, and after large changes in geomagnetic field.

Mapping evolutionary process: a multi-taxa approach to conservation prioritization

PubMed Central

Thomassen, Henri A; Fuller, Trevon; Buermann, Wolfgang; Milá, Borja; Kieswetter, Charles M; Jarrín-V, Pablo; Cameron, Susan E; Mason, Eliza; Schweizer, Rena; Schlunegger, Jasmin; Chan, Janice; Wang, Ophelia; Peralvo, Manuel; Schneider, Christopher J; Graham, Catherine H; Pollinger, John P; Saatchi, Sassan; Wayne, Robert K; Smith, Thomas B

2011-01-01

Human-induced land use changes are causing extensive habitat fragmentation. As a result, many species are not able to shift their ranges in response to climate change and will likely need to adapt in situ to changing climate conditions. Consequently, a prudent strategy to maintain the ability of populations to adapt is to focus conservation efforts on areas where levels of intraspecific variation are high. By doing so, the potential for an evolutionary response to environmental change is maximized. Here, we use modeling approaches in conjunction with environmental variables to model species distributions and patterns of genetic and morphological variation in seven Ecuadorian amphibian, bird, and mammal species. We then used reserve selection software to prioritize areas for conservation based on intraspecific variation or species-level diversity. Reserves selected using species richness and complementarity showed little overlap with those based on genetic and morphological variation. Priority areas for intraspecific variation were mainly located along the slopes of the Andes and were largely concordant among species, but were not well represented in existing reserves. Our results imply that in order to maximize representation of intraspecific variation in reserves, genetic and morphological variation should be included in conservation prioritization. PMID:25567981

Mapping evolutionary process: a multi-taxa approach to conservation prioritization.

PubMed

Thomassen, Henri A; Fuller, Trevon; Buermann, Wolfgang; Milá, Borja; Kieswetter, Charles M; Jarrín-V, Pablo; Cameron, Susan E; Mason, Eliza; Schweizer, Rena; Schlunegger, Jasmin; Chan, Janice; Wang, Ophelia; Peralvo, Manuel; Schneider, Christopher J; Graham, Catherine H; Pollinger, John P; Saatchi, Sassan; Wayne, Robert K; Smith, Thomas B

2011-03-01

Human-induced land use changes are causing extensive habitat fragmentation. As a result, many species are not able to shift their ranges in response to climate change and will likely need to adapt in situ to changing climate conditions. Consequently, a prudent strategy to maintain the ability of populations to adapt is to focus conservation efforts on areas where levels of intraspecific variation are high. By doing so, the potential for an evolutionary response to environmental change is maximized. Here, we use modeling approaches in conjunction with environmental variables to model species distributions and patterns of genetic and morphological variation in seven Ecuadorian amphibian, bird, and mammal species. We then used reserve selection software to prioritize areas for conservation based on intraspecific variation or species-level diversity. Reserves selected using species richness and complementarity showed little overlap with those based on genetic and morphological variation. Priority areas for intraspecific variation were mainly located along the slopes of the Andes and were largely concordant among species, but were not well represented in existing reserves. Our results imply that in order to maximize representation of intraspecific variation in reserves, genetic and morphological variation should be included in conservation prioritization.

Relative importance of local- and large-scale drivers of alpine soil microarthropod communities.

PubMed

Mitchell, Ruth J; Urpeth, Hannah M; Britton, Andrea J; Black, Helaina; Taylor, Astrid R

2016-11-01

Nitrogen (N) deposition and climate are acknowledged drivers of change in biodiversity and ecosystem function at large scales. However, at a local scale, their impact on functions and community structure of organisms is filtered by drivers like habitat quality and food quality/availability. This study assesses the relative impact of large-scale factors, N deposition and climate (rainfall and temperature), versus local-scale factors of habitat quality and food quality/availability on soil fauna communities at 15 alpine moss-sedge heaths along an N deposition gradient in the UK. Habitat quality and food quality/availability were the primary drivers of microarthropod communities. No direct impacts of N deposition on the microarthropod community were observed, but induced changes in habitat quality (decline in moss cover and depth) and food quality (decreased vegetation C:N) associated with increased N deposition strongly suggest an indirect impact of N. Habitat quality and climate explained variation in the composition of the Oribatida, Mesostigmata, and Collembola communities, while only habitat quality significantly impacted the Prostigmata. Food quality and prey availability were important in explaining the composition of the oribatid and mesostigmatid mite communities, respectively. This study shows that, in alpine habitats, soil microarthropod community structure responds most strongly to local-scale variation in habitat quality and food availability rather than large-scale variation in climate and pollution. However, given the strong links between N deposition and the key habitat quality parameters, we conclude that N deposition indirectly drives changes in the soil microarthropod community, suggesting a mechanism by which large-scale drivers indirectly impacts these functionally important groups.

Thermo-mechanical behavior of power electronic packaging assemblies: From characterization to predictive simulation of lifetimes

NASA Astrophysics Data System (ADS)

Dalverny, O.; Alexis, J.

2018-02-01

This article deals with thermo-mechanical behavior of power electronic modules used in several transportation applications as railway, aeronautic or automotive systems. Due to a multi-layered structures, involving different materials with a large variation of coefficient of thermal expansion, temperature variations originated from active or passive cycling (respectively from die dissipation or environmental constraint) induces strain and stresses field variations, giving fatigue phenomenon of the system. The analysis of the behavior of these systems and their dimensioning require the implementation of complex modeling strategies by both the multi-physical and the multi-scale character of the power modules. In this paper we present some solutions for studying the thermomechanical behavior of brazed assemblies as well as taking into account the interfaces represented by the numerous metallizations involved in the process assembly.

Best-Matched Internal Standard Normalization in Liquid Chromatography-Mass Spectrometry Metabolomics Applied to Environmental Samples.

PubMed

Boysen, Angela K; Heal, Katherine R; Carlson, Laura T; Ingalls, Anitra E

2018-01-16

The goal of metabolomics is to measure the entire range of small organic molecules in biological samples. In liquid chromatography-mass spectrometry-based metabolomics, formidable analytical challenges remain in removing the nonbiological factors that affect chromatographic peak areas. These factors include sample matrix-induced ion suppression, chromatographic quality, and analytical drift. The combination of these factors is referred to as obscuring variation. Some metabolomics samples can exhibit intense obscuring variation due to matrix-induced ion suppression, rendering large amounts of data unreliable and difficult to interpret. Existing normalization techniques have limited applicability to these sample types. Here we present a data normalization method to minimize the effects of obscuring variation. We normalize peak areas using a batch-specific normalization process, which matches measured metabolites with isotope-labeled internal standards that behave similarly during the analysis. This method, called best-matched internal standard (B-MIS) normalization, can be applied to targeted or untargeted metabolomics data sets and yields relative concentrations. We evaluate and demonstrate the utility of B-MIS normalization using marine environmental samples and laboratory grown cultures of phytoplankton. In untargeted analyses, B-MIS normalization allowed for inclusion of mass features in downstream analyses that would have been considered unreliable without normalization due to obscuring variation. B-MIS normalization for targeted or untargeted metabolomics is freely available at https://github.com/IngallsLabUW/B-MIS-normalization .

Analysis of Natural Variation in Bermudagrass (Cynodon dactylon) Reveals Physiological Responses Underlying Drought Tolerance

PubMed Central

Cheng, Zhangmin; Ye, Tiantian; Chan, Zhulong

2012-01-01

Bermudagrass (Cynodon dactylon) is a widely used warm-season turfgrass and one of the most drought tolerant species. Dissecting the natural variation in drought tolerance and physiological responses will bring us powerful basis and novel insight for plant breeding. In the present study, we evaluated the natural variation of drought tolerance among nine bermudagrass varieties by measuring physiological responses after drought stress treatment through withholding water. Three groups differing in drought tolerance were identified, including two tolerant, five moderately tolerant and two susceptible varieties. Under drought stress condition, drought sensitive variety (Yukon) showed relative higher water loss, more severe cell membrane damage (EL), and more accumulation of hydrogen peroxide (H2O2) and malondialdehyde (MDA), while drought tolerant variety (Tifgreen) exhibited significantly higher antioxidant enzymes activities. Further results indicated that drought induced cell injury in different varieties (Yukon, SR9554 and Tifgreen) exhibited liner correlation with leaf water content (LWC), H2O2 content, MDA content and antioxidant enzyme activities. Additionally, Tifgreen plants had significantly higher levels of osmolytes (proline level and soluble sugars) when compared with Yukon and SR9554 under drought stress condition. Taken together, our results indicated that natural variation of drought stress tolerance in bermudagrass varieties might be largely related to the induced changes of water status, osmolyte accumulation and antioxidant defense system. PMID:23285294

Structure of the Koyna-Warna Seismic Zone, Maharashtra, India: A possible model for large induced earthquakes elsewhere

USGS Publications Warehouse

Catchings, Rufus D.; Dixit, M.M.; Goldman, Mark R.; Kumar, S.

2015-01-01

The Koyna-Warna area of India is one of the best worldwide examples of reservoir-induced seismicity, with the distinction of having generated the largest known induced earthquake (M6.3 on 10 December 1967) and persistent moderate-magnitude (>M5) events for nearly 50 years. Yet, the fault structure and tectonic setting that has accommodated the induced seismicity is poorly known, in part because the seismic events occur beneath a thick sequence of basalt layers. On the basis of the alignment of earthquake epicenters over an ~50 year period, lateral variations in focal mechanisms, upper-crustal tomographic velocity images, geophysical data (aeromagnetic, gravity, and magnetotelluric), geomorphic data, and correlation with similar structures elsewhere, we suggest that the Koyna-Warna area lies within a right step between northwest trending, right-lateral faults. The sub-basalt basement may form a local structural depression (pull-apart basin) caused by extension within the step-over zone between the right-lateral faults. Our postulated model accounts for the observed pattern of normal faulting in a region that is dominated by north-south directed compression. The right-lateral faults extend well beyond the immediate Koyna-Warna area, possibly suggesting a more extensive zone of seismic hazards for the central India area. Induced seismic events have been observed many places worldwide, but relatively large-magnitude induced events are less common because critically stressed, preexisting structures are a necessary component. We suggest that releasing bends and fault step-overs like those we postulate for the Koyna-Warna area may serve as an ideal tectonic environment for generating moderate- to large- magnitude induced (reservoir, injection, etc.) earthquakes.

Automated X-Ray Diffraction of Irradiated Materials

DOE PAGES

Rodman, John; Lin, Yuewei; Sprouster, David; ...

2017-10-26

Synchrotron-based X-ray diffraction (XRD) and small-angle Xray scattering (SAXS) characterization techniques used on unirradiated and irradiated reactor pressure vessel steels yield large amounts of data. Machine learning techniques, including PCA, offer a novel method of analyzing and visualizing these large data sets in order to determine the effects of chemistry and irradiation conditions on the formation of radiation induced precipitates. In order to run analysis on these data sets, preprocessing must be carried out to convert the data to a usable format and mask the 2-D detector images to account for experimental variations. Once the data has been preprocessed, itmore » can be organized and visualized using principal component analysis (PCA), multi-dimensional scaling, and k-means clustering. In conclusion, from these techniques, it is shown that sample chemistry has a notable effect on the formation of the radiation induced precipitates in reactor pressure vessel steels.« less

Towards a global accurate model for horizontal and vertical elastic response of the Earth to seasonal hydrology derived from GRACE

NASA Astrophysics Data System (ADS)

Chanard, K.; Fleitout, L.; Calais, E.; Barbot, S.; Avouac, J. P.

2016-12-01

Elastic deformation of the Earth induced by seasonal variations in hydrology is now well established. We compute the vertical and horizontal deformation induced by large variations of continental water storage at a set of 195 globally distributed continuous Global Positioning System (cGPS) stations. Seasonal loading is derived from the Gravity and Recovery Climate experiment (GRACE) equivalent water height data, where we first account for non observable degree-1 components using previous results (Swenson et al., 2010). While the vertical displacements are well predicted by the model, the horizontal components are systematically underpredicted and out-of- phase with the observations. This global result confirms previous difficulties to predict horizontal seasonal site positions at a regional scale. We discuss possible contributions to this misfit (thermal expansion, draconitic effects, etc.) and show a dramatic improvement when we derive degree-one deformation plus reference frame differences between model and observations. The fit in phase and amplitude of the seasonal deformation model to the horizontal GPS measurements is improved and the fit to the vertical component is not affected. However, the amplitude of global seasonal horizontal displacement remains slightly underpredicted. We explore several hypothesis including the validity of a purely elastic model derived from seismic estimates at an annual time scale. We show that mantle volume variations due to mineral phase transitions may play a role in the seasonal deformation and, as a by-product, use this seasonal deformation to provide a lower bound of the transient astenospheric viscosity. Our study aims at providing an accurate model for horizontal and vertical seasonal deformation of the Earth induced by variations in surface hydrology derived from GRACE.

Solar-terrestrial coupling through atmospheric electricity

NASA Technical Reports Server (NTRS)

Roble, R. G.; Hays, P. B.

1979-01-01

There are a number of measurements of electrical variations that suggest a solar-terrestrial influence on the global atmospheric electrical circuit. The measurements show variations associated with solar flares, solar magnetic sector boundary crossings, geomagnetic activity, aurorae, differences between ground current and potential gradients at high and low latitudes, and solar cycle variations. The evidence for each variation is examined. Both the experimental evidence and the calculations made with a global model of atmospheric electricity indicate that there is solar-terrestrial coupling through atmospheric electricity which operates by altering the global electric current and field distribution. A global redistribution of currents and fields can be caused by large-scale changes in electrical conductivity, by alteration of the columnar resistance between thunderstorm cloud tops and the ionosphere, or by both. If the columnar resistance is altered above thunderstorms, more current will flow in the global circuit, changing the ionospheric potential and basic circuit variables such as current density and electric fields. The observed variations of currents and fields during solar-induced disturbances are generally less than 50% of mean values near the earth's surface.

Atmospheric Response to Zonal Variations in Midlatitude SST: Transient and Stationary Eddies and Their Feedback(.

NASA Astrophysics Data System (ADS)

Inatsu, Masaru; Mukougawa, Hitoshi; Xie, Shang-Ping

2003-10-01

Midwinter storm track response to zonal variations in midlatitude sea surface temperatures (SSTs) has been investigated using an atmospheric general circulation model under aquaplanet and perpetual-January conditions. Zonal wavenumber-1 SST variations with a meridionally confined structure are placed at various latitudes. Having these SST variations centered at 30°N leads to a zonally localized storm track, while the storm track becomes nearly zonally uniform when the same SST forcing is moved farther north at 40° and 50°N. Large (small) baroclinic energy conversion north of the warm (cold) SST anomaly near the axis of the storm track (near 40°N) is responsible for the large (small) storm growth. The equatorward transfer of eddy kinetic energy by the ageostrophic motion and the mechanical damping are important to diminish the storm track activity in the zonal direction.Significant stationary eddies form in the upper troposphere, with a ridge (trough) northeast of the warm (cold) SST anomaly at 30°N. Heat and vorticity budget analyses indicate that zonally localized condensational heating in the storm track is the major cause for these stationary eddies, which in turn exert a positive feedback to maintain the localized storm track by strengthening the vertical shear near the surface. These results indicate an active role of synoptic eddies in inducing deep, tropospheric-scale response to midlatitude SST variations. Finally, the application of the model results to the real atmosphere is discussed.

Large-scale, near-Earth, magnetic fields from external sources and the corresponding induced internal field

NASA Technical Reports Server (NTRS)

Langel, R. A.; Estes, R. H.

1983-01-01

Data from MAGSAT analyzed as a function of the Dst index to determine the first degree/order spherical harmonic description of the near-Earth external field and its corresponding induced field. The analysis was done separately for data from dawn and dusk. The MAGSAT data was compared with POGO data. A local time variation of the external field persists even during very quiet magnetic conditions; both a diurnal and 8-hour period are present. A crude estimate of Sq current in the 45 deg geomagnetic latitude range is obtained for 1966 to 1970. The current strength, located in the ionosphere and induced in the Earth, is typical of earlier determinations from surface data, although its maximum is displaced in local time from previous results.

Large-scale, near-field magnetic fields from external sources and the corresponding induced internal field

NASA Technical Reports Server (NTRS)

Langel, R. A.; Estes, R. H.

1985-01-01

Data from Magsat analyzed as a function of the Dst index to determine the first degree/order spherical harmonic description of the near-earth external field and its corresponding induced field. The analysis was done separately for data from dawn and dusk. The Magsat data was compared with POGO data. A local time variation of the external field persists even during very quiet magnetic conditions; both a diurnal and 8-hour period are present. A crude estimate of Sq current in the 45 deg geomagnetic latitude range is obtained for 1966 to 1970. The current strength, located in the ionosphere and induced in the earth, is typical of earlier determinations from surface data, although its maximum is displaced in local time from previous results.

174Yb 3P1 level relaxation found via weak magnetic field dependence of collision-induced stimulated photon echo

NASA Astrophysics Data System (ADS)

Rubtsova, N. N.; Gol’dort, V. G.; Khvorostov, E. B.; Kochubei, S. A.; Reshetov, V. A.

2018-06-01

Collision-induced stimulated photon echo generated at transition was analyzed theoretically and investigated experimentally in the gaseous mixture of ytterbium vapour diluted with a large amount of buffer gas xenon in the presence of a weak longitudinal magnetic field. The inter-combination transition of 174Yb (6s2) 1S(6s6p) 3P1 was used; all experimental parameters were carefully controlled for their correspondence to the broad spectral line conditions. The curve representing the collision-induced stimulated photon echo variations versus a weak magnetic field strength showed very good agreement with the corresponding theoretical curve; this agreement permitted getting the decay rates for 174Yb level 3P1 orientation and alignment in collisions with Xe.

Solar influence on climate during the past millennium: Results from transient simulations with the NCAR Climate System Model

PubMed Central

Ammann, Caspar M.; Joos, Fortunat; Schimel, David S.; Otto-Bliesner, Bette L.; Tomas, Robert A.

2007-01-01

The potential role of solar variations in modulating recent climate has been debated for many decades and recent papers suggest that solar forcing may be less than previously believed. Because solar variability before the satellite period must be scaled from proxy data, large uncertainty exists about phase and magnitude of the forcing. We used a coupled climate system model to determine whether proxy-based irradiance series are capable of inducing climatic variations that resemble variations found in climate reconstructions, and if part of the previously estimated large range of past solar irradiance changes could be excluded. Transient simulations, covering the published range of solar irradiance estimates, were integrated from 850 AD to the present. Solar forcing as well as volcanic and anthropogenic forcing are detectable in the model results despite internal variability. The resulting climates are generally consistent with temperature reconstructions. Smaller, rather than larger, long-term trends in solar irradiance appear more plausible and produced modeled climates in better agreement with the range of Northern Hemisphere temperature proxy records both with respect to phase and magnitude. Despite the direct response of the model to solar forcing, even large solar irradiance change combined with realistic volcanic forcing over past centuries could not explain the late 20th century warming without inclusion of greenhouse gas forcing. Although solar and volcanic effects appear to dominate most of the slow climate variations within the past thousand years, the impacts of greenhouse gases have dominated since the second half of the last century. PMID:17360418

Method for identifying mutagenic agents which induce large, multilocus deletions in DNA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, W.E.C.; Belouchi, A.; Dewyse, P.

1993-07-13

A method of identifying a mutagenic agent is described which includes a large, multilocus deletions in DNA in mammalian cells comprising: (i) exposing a class III heterozygous CHO cell line to a potential mutagenic agent under investigation, and allowing any mutation of the cell line to proceed, said cell line being characterized in that a restriction fragment length variation exists in on mutation it becomes resistant to 2,6-diaminopurine and in that the DNA sequence adjacent to the two alleles of the APRT gene such that the DNA sequence adjacent to one of the two alleles can be digested with themore » enzyme BclI but the DNA sequence variation adjacent to the other of the two alleles cannot be digested with BclI, (ii) isolating induced mutations of the cell line deficient in APRT function, (iii) isolating DNA from the induced mutants, (iv) digesting the isolated DNA with BclI enzyme to produce digested fragments including a 19 kb fragment and any 2 kb fragment, which fragments hybridize with the labeled probe derived from DNA fragment PDI, (v) separating any digested fragments, (vi) transferring the separated fragments of (v) to a solid support, (vii) hybridizing the supported separated fragments with a labeled probe derived from the clone DNA fragment PD 1, (viii) determining fragments having undergone loss of the 2 kb band identified by the probe, as an identification of parent mutants in which the loss occurred, and (ix) evaluating the mutating ability of the potential mutagenic agent.« less

Effects of variables upon pyrotechnically induced shock response spectra

NASA Technical Reports Server (NTRS)

Smith, J. L.

1986-01-01

Throughout the aerospace industry, large variations of 50 percent (6 dB) or more are continually noted for linear shaped charge (LSC) generated shock response spectra (SRS) from flight data (from the exact same location on different flights) and from plate tests (side by side measurements on the same test). A research program was developed to investigate causes of these large SRS variations. A series of ball drop calibration tests to verify calibration of accelerometers and a series of plate tests to investigate charge and assembly variables were performed. The resulting data were analyzed to determine if and to what degree manufacturing and assembly variables, distance from the shock source, data acquisition instrumentation, and shock energy propagation affect the SRS. LSC variables consisted of coreload, standoff, and apex angle. The assembly variable was the torque on the LSC holder. Other variables were distance from source of accelerometers, accelerometer mounting methods, and joint effects. Results indicated that LSC variables did not affect SRS as long as the plate was severed. Accelerometers mounted on mounting blocks showed significantly lower levels above 5000 Hz. Lap joints did not affect SRS levels. The test plate was mounted in an almost free-free state; therefore, distance from the source did not affect the SRS. Several varieties and brands of accelerometers were used, and all but one demonstrated very large variations in SRS.

Silicon microring resonators

NASA Astrophysics Data System (ADS)

Tan, Ying; Dai, Daoxin

2018-05-01

Silicon microring resonators (MRRs) are very popular for many applications because of the advantages of footprint compactness, easy scalability, and functional versatility. Ultra-compact silicon MRRs with box-like spectral responses are realized with a very large free-spectral range (FSR) by introducing bent directional couplers. The measured box-like spectral response has an FSR of >30 nm. The permanent wavelength-alignment techniques for MRRs are also presented, including the laser-induced local-oxidation technique as well as the local-etching technique. With these techniques, one can control finely the permanent wavelength shift, which is also large enough to compensate the random wavelength variation due to the random fabrication errors.

a Study of the Impact of Doubling Carbon Dioxide and Solar Radiation Variations on the Climate System.

NASA Astrophysics Data System (ADS)

Chu, Shaoping

The exchange of moisture and heat between the atmosphere and the Earth's surface fundamentally affect the dynamics and thermodynamics of the climate system. In order to trace moisture flow through the climate system and examine its impact on climate, a hydrologic cycle and a land energy balance have been developed and incorporated into a coupled climate-thermodynamic sea ice (CCSI) model. The expanded CCSI model has been tested by comparing computed climate parameters with available observations and GCM modeling results. In general, the expanded model does a good job in simulating the large scale features of the atmospheric circulation and precipitation in both space and time. The expanded model has been used to examine the possibility that increased levels of CO_2 in the atmosphere may induce the growth of Northern Hemisphere ice sheets. Results of the study indicate that if summer ice albedo is high enough, and there is some mechanism for initially maintaining ice through the summer season, then it may be possible to have ice sheet growth under the conditions CO_2 induced warming, mainly the result of decreased summer ice melt in response to the higher land ice albedo, and not an increase in precipitation. The expanded model has also been used to examine the impact of Milankovitch solar radiation variations on the climate system, to study the mechanisms that produce glacial-interglacial cycles, especially with respect to the initiation of ice sheets. The results show the Milankovitch solar radiation variations affect the climate system most in the polar regions with the mean annual surface air temperature varying directly in response to changes in the annually averaged incoming solar radiation. However, the seasonal variations in the surface air temperatures are much more complex with large magnitude variations for brief times during the year. The study indicates that ice sheets may start to grow under the conditions of low insolation that occurred at 25, 70, and 115 kyr BP and a land ice minimum albedo of 0.53, with the largest growth rate at 115 kyr BP, approximately when the current 100 kyr cycle began as observed in the geological record.

Hourly, daily, and seasonal variability in the absorption spectra of chromophoric dissolved organic matter in a eutrophic, humic lake

NASA Astrophysics Data System (ADS)

Müller, R. A.; Kothawala, D. N.; Podgrajsek, E.; Sahlée, E.; Koehler, B.; Tranvik, L. J.; Weyhenmeyer, G. A.

2014-10-01

The short-term (hourly and daily) variation in chromophoric dissolved organic matter (CDOM) in lakes is largely unknown. We assessed the spectral characteristics of light absorption by CDOM in a eutrophic, humic shallow mixed lake of temperate Sweden at a high-frequency (30 min) interval and during a full growing season (May to October). Physical time series, such as solar radiation, temperature, wind, and partial pressures of carbon dioxide in water and air, were measured synchronously. We identified a strong radiation-induced summer CDOM loss (25 to 50%) that developed over 4 months, which was accompanied by strong changes in CDOM absorption spectral shape. The magnitude of the CDOM loss exceeded subhourly to daily variability by an order of magnitude. Applying Fourier analysis, we demonstrate that variation in CDOM remained largely unaffected by rapid shifts in weather, and no apparent response to in-lake dissolved organic carbon production was found. In autumn, CDOM occasionally showed variation at hourly to daily time scales, reaching a maximum daily coefficient of variation of 15%. We suggest that lake-internal effects on CDOM are quenched in humic lake waters by dominating effects associated with imported CDOM and solar exposure. Since humic lake waters belong to one of the most abundant lake types on Earth, our results have important implications for the understanding of global CDOM cycling.

Impact of volcanic eruptions on the climate of the 1st millennium AD in a comprehensive climate simulation

NASA Astrophysics Data System (ADS)

Wagner, Sebastian; Zorita, Eduardo

2015-04-01

The climate of the 1st millennium AD shows some remarkable differences compared to the last millennium concerning variation in external forcings. Together with an orbitally induced increased solar insolation during the northern hemisphere summer season and a general lack of strong solar minima, the frequency and intensity of large tropical and extratropical eruptions is decreased. Here we present results of a new climate simulation carried out with the comprehensive Earth System Model MPI-ESM-P forced with variations in orbital, solar, volcanic and greenhouse gas variations and land use changes for the last 2,100 years. The atmospheric model has a horizontal resolution of T63 (approx. 125x125 km) and therefore also allows investigations of regional-to-continental scale climatic phenomena. The volcanic forcing was reconstructed based on a publication by Sigl et al. (2013) using the sulfate records of the NEEM and WAIS ice cores. To obtain information on the aerosol optical depth (AOD) these sulfate records were scaled to an established reconstruction from Crowley and Unterman (2010), which is also a standard forcing in the framework of CMIP5/PMIP3. A comparison between the newly created data set with the Crowley and Unterman dataset reveals that the new reconstruction shows in general weaker intensities, especially of the large tropical outbreaks and fewer northern hemispheric small-to-medium scale eruptions. However, the general pattern in the overlapping period is similar. A hypothesis that can be tested with the simulation is whether the reduced volcanic intensity of the 1st millennium AD contributed to the elevated temperature levels over Europe, evident within a new proxy-based reconstruction. On the other hand, the few but large volcanic eruptions, e.g. the 528 AD event, also induced negative decadal-scale temperature anomalies. Another interesting result of the simulation relates to the 79 AD eruption of the Vesuvius, which caused the collapse of the city of Pompeii and its surroundings. Despite its severe local effects the eruption does not show a clear-cut hemispheric or global cooling. Therefore the simulation allows investigations on the effect of individual and clustered eruptions on the climate in the 1st millennium AD and its potential influence to human induced migration periods and decay of cultures in different regions.

Triggering and modulation of geyser eruptions in Yellowstone National Park by earthquakes, earth tides, and weather

USGS Publications Warehouse

Hurwitz, Shaul; Sohn, Robert A.; Luttrell, Karen; Manga, Michael

2014-01-01

We analyze intervals between eruptions (IBEs) data acquired between 2001 and 2011 at Daisy and Old Faithful geysers in Yellowstone National Park. We focus our statistical analysis on the response of these geysers to stress perturbations from within the solid earth (earthquakes and earth tides) and from weather (air pressure and temperature, precipitation, and wind). We conclude that (1) the IBEs of these geysers are insensitive to periodic stresses induced by solid earth tides and barometric pressure variations; (2) Daisy (pool geyser) IBEs lengthen by evaporation and heat loss in response to large wind storms and cold air; and (3) Old Faithful (cone geyser) IBEs are not modulated by air temperature and pressure variations, wind, and precipitation, suggesting that the subsurface water column is decoupled from the atmosphere. Dynamic stress changes of 0.1−0.2 MPa resulting from the 2002 M-7.9 Denali, Alaska, earthquake surface waves caused a statistically significant shortening of Daisy geyser's IBEs. Stresses induced by other large global earthquakes during the study period were at least an order of magnitude smaller. In contrast, dynamic stresses of >0.5 MPa from three large regional earthquakes in 1959, 1975, and 1983 caused lengthening of Old Faithful's IBEs. We infer that most subannual geyser IBE variability is dominated by internal processes and interaction with other geysers. The results of this study provide quantitative bounds on the sensitivity of hydrothermal systems to external stress perturbations and have implications for studying the triggering and modulation of volcanic eruptions by external forces.

Implementation and validation of a wake model for low-speed forward flight

NASA Technical Reports Server (NTRS)

Komerath, Narayanan M.; Schreiber, Olivier A.

1987-01-01

The computer implementation and calculations of the induced velocities produced by a wake model consisting of a trailing vortex system defined from a prescribed time averaged downwash distribution are detailed. Induced velocities are computed by approximating each spiral turn by a pair of large straight vortex segments positioned at critical points relative to where the induced velocity is required. A remainder term for the rest of the spiral is added. This approach results in decreased computation time compared to classical models where each spiral turn is broken down in small straight vortex segments. The model includes features such a harmonic variation of circulation, downwash outside of the blade and/or outside the tip path plane, blade bound vorticity induced velocity with harmonic variation of circulation and time averaging. The influence of various options and parameters on the results are investigated and results are compared to experimental field measurements with which, a resonable agreement is obtained. The capabilities of the model as well as its extension possibilities are studied. The performance of the model in predicting the recently-acquired NASA Langley Inflow data base for a four-bladed rotor is compared to that of the Scully Free Wake code, a well-established program which requires much greater computational resources. It is found that the two codes predict the experimental data with essentially the same accuracy, and show the same trends.

Spatiotemporal patterns of fire-induced forest mortality in boreal regions and its potential drivers

NASA Astrophysics Data System (ADS)

Yang, J.; Tian, H.; Pan, S.; Hansen, M.; Wang, Y.

2017-12-01

Wildfire is the major natural disturbance in boreal forests, which have substantially affected various biological and biophysical processes. Although a few previous studies examined fire severity in boreal regions and reported a higher fire-induced forest mortality in boreal North America than in boreal Eurasia, it remains unclear how this mortality changes over time and how environmental factors affect the temporal dynamics of mortality at a large scale. By using a combination of multiple sources of satellite observations, we investigate the spatiotemporal patterns of fire-induced forest mortality in boreal regions, and examine the contributions of potential drivers. Our results show that forest composition is the key factor influencing the spatial variations of fire mortality across ecoregions. For the temporal variations, we find that the late-season burning was associated with higher fire intensity, which lead to greater forest mortality than the early-season burning. Forests burned in the warm and dry years had greater mortality than those burned in the cool and wet years. Our findings suggest that climate warming and drying not only stimulated boreal fire frequency, but also enhanced fire severity and forest mortality. Due to the significant effects of forest mortality on vegetation structure and ecosystem carbon dynamics, the spatiotemporal changes of fire-induced forest mortality should be explicitly considered to better understand fire impacts on regional and global climate change.

Light-driven growth in Amazon evergreen forests explained by seasonal variations of vertical canopy structure.

PubMed

Tang, Hao; Dubayah, Ralph

2017-03-07

Light-regime variability is an important limiting factor constraining tree growth in tropical forests. However, there is considerable debate about whether radiation-induced green-up during the dry season is real, or an apparent artifact of the remote-sensing techniques used to infer seasonal changes in canopy leaf area. Direct and widespread observations of vertical canopy structures that drive radiation regimes have been largely absent. Here we analyze seasonal dynamic patterns between the canopy and understory layers in Amazon evergreen forests using observations of vertical canopy structure from a spaceborne lidar. We discovered that net leaf flushing of the canopy layer mainly occurs in early dry season, and is followed by net abscission in late dry season that coincides with increasing leaf area of the understory layer. Our observations of understory development from lidar either weakly respond to or are not correlated to seasonal variations in precipitation or insolation, but are strongly related to the seasonal structural dynamics of the canopy layer. We hypothesize that understory growth is driven by increased light gaps caused by seasonal variations of the canopy. This light-regime variability that exists in both spatial and temporal domains can better reveal the drought-induced green-up phenomenon, which appears less obvious when treating the Amazon forests as a whole.

Obliquity evolution of the minor satellites of Pluto and Charon

NASA Astrophysics Data System (ADS)

Quillen, Alice C.; Nichols-Fleming, Fiona; Chen, Yuan-Yuan; Noyelles, Benoît

2017-09-01

New Horizons mission observations show that the small satellites Styx, Nix, Kerberos and Hydra, of the Pluto-Charon system, have not tidally spun-down to near synchronous spin states and have high obliquities with respect to their orbit about the Pluto-Charon binary (Weaver, 2016). We use a damped mass-spring model within an N-body simulation to study spin and obliquity evolution for single spinning non-round bodies in circumbinary orbit. Simulations with tidal dissipation alone do not show strong obliquity variations from tidally induced spin-orbit resonance crossing and this we attribute to the high satellite spin rates and low orbital eccentricities. However, a tidally evolving Styx exhibits intermittent obliquity variations and episodes of tumbling. During a previous epoch where Charon migrated away from Pluto, the minor satellites could have been trapped in orbital mean motion inclination resonances. An outward migrating Charon induces large variations in Nix and Styx's obliquities. The cause is a commensurability between the mean motion resonance frequency and the spin precession rate of the spinning body. As the minor satellites are near mean motion resonances, this mechanism could have lifted the obliquities of all four minor satellites. The high obliquities need not be primordial if the minor satellites were at one time captured into mean motion resonances.

Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination.

PubMed

Voigt, Emily A; Haralambieva, Iana H; Larrabee, Beth L; Kennedy, Richard B; Ovsyannikova, Inna G; Schaid, Daniel J; Poland, Gregory A

2018-01-30

Rubella vaccination induces widely variable immune responses in vaccine recipients. While rubella vaccination is effective at inducing immunity to rubella infection in most subjects, up to 5% of individuals do not achieve or maintain long-term protective immunity. To expand upon our previous work identifying genetic polymorphisms that are associated with these interindividual differences in humoral immunity to rubella virus, we performed a genome-wide association study in a large cohort of 1843 subjects to discover single-nucleotide polymorphisms (SNPs) associated with rubella virus-specific cellular immune responses. We identified SNPs in the Wilms tumor protein gene (WT1) that were significantly associated (P < 5 × 10-8) with interindividual variations in rubella-specific interleukin 6 secretion from subjects' peripheral blood mononuclear cells postvaccination. No SNPs were found to be significantly associated with variations in rubella-specific interferon-γ secretion. Our findings demonstrate that genetic polymorphisms in the WT1 gene in subjects of European ancestry are associated with interindividual differences in rubella virus-specific cellular immunity after measles-mumps-rubella II vaccination. © The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

The imprint of surface fluxes and transport on variations in total column carbon dioxide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keppel-Aleks, G; Wennberg, PO; Washenfelder, RA

2012-01-01

New observations of the vertically integrated CO{sub 2} mixing ratio, , from ground-based remote sensing show that variations in are primarily determined by large-scale flux patterns. They therefore provide fundamentally different information than observations made within the boundary layer, which reflect the combined influence of large-scale and local fluxes. Observations of both and CO{sub 2} concentrations in the free troposphere show that large-scale spatial gradients induce synoptic-scale temporal variations in in the Northern Hemisphere midlatitudes through horizontal advection. Rather than obscure the signature of surface fluxes on atmospheric CO{sub 2}, these synoptic-scale variationsmore » provide useful information that can be used to reveal the meridional flux distribution. We estimate the meridional gradient in from covariations in and potential temperature, {theta}, a dynamical tracer, on synoptic timescales to evaluate surface flux estimates commonly used in carbon cycle models. We find that simulations using Carnegie Ames Stanford Approach (CASA) biospheric fluxes underestimate both the seasonal cycle amplitude throughout the Northern Hemisphere midlatitudes and the meridional gradient during the growing season. Simulations using CASA net ecosystem exchange (NEE) with increased and phase-shifted boreal fluxes better fit the observations. Our simulations suggest that climatological mean CASA fluxes underestimate boreal growing season NEE (between 45-65{sup o} N) by {approx}40%. We describe the implications for this large seasonal exchange on inference of the net Northern Hemisphere terrestrial carbon sink.« less

Bridging Enzymatic Structure Function via Mechanics: A Coarse-Grain Approach.

PubMed

Sacquin-Mora, S

2016-01-01

Flexibility is a central aspect of protein function, and ligand binding in enzymes involves a wide range of structural changes, ranging from large-scale domain movements to small loop or side-chain rearrangements. In order to understand how the mechanical properties of enzymes, and the mechanical variations that are induced by ligand binding, relate to enzymatic activity, we carried out coarse-grain Brownian dynamics simulations on a set of enzymes whose structures in the unbound and ligand-bound forms are available in the Protein Data Bank. Our results show that enzymes are remarkably heterogeneous objects from a mechanical point of view and that the local rigidity of individual residues is tightly connected to their part in the protein's overall structure and function. The systematic comparison of the rigidity of enzymes in their unbound and bound forms highlights the fact that small conformational changes can induce large mechanical effects, leading to either more or less flexibility depending on the enzyme's architecture and the location of its ligand-biding site. These mechanical variations target a limited number of specific residues that occupy key locations for enzymatic activity, and our approach thus offers a mean to detect perturbation-sensitive sites in enzymes, where the addition or removal of a few interactions will lead to important changes in the proteins internal dynamics. © 2016 Elsevier Inc. All rights reserved.

Wavefront control of high-power laser beams in the National Ignition Facility (NIF)

NASA Astrophysics Data System (ADS)

Zacharias, Richard A.; Bliss, Erlan S.; Winters, Scott; Sacks, Richard A.; Feldman, Mark; Grey, Andrew; Koch, Jeffrey A.; Stolz, Christopher J.; Toeppen, John S.; Van Atta, Lewis; Woods, Bruce W.

2000-04-01

The use of lasers as the driver for inertial confinement fusion and weapons physics experiments is based on their ability to produce high-energy short pulses in a beam with low divergence. Indeed, the focusability of high quality laser beams far exceeds alternate technologies and is a major factor in the rationale for building high power lasers for such applications. The National Ignition Facility (NIF) is a large, 192-beam, high-power laser facility under construction at the Lawrence Livermore National Laboratory for fusion and weapons physics experiments. Its uncorrected minimum focal spot size is limited by laser system aberrations. The NIF includes a Wavefront Control System to correct these aberrations to yield a focal spot small enough for its applications. Sources of aberrations to be corrected include prompt pump-induced distortions in the laser amplifiers, previous-shot thermal distortions, beam off-axis effects, and gravity, mounting, and coating-induced optic distortions. Aberrations from gas density variations and optic-manufacturing figure errors are also partially corrected. This paper provides an overview of the NIF Wavefront Control System and describes the target spot size performance improvement it affords. It describes provisions made to accommodate the NIF's high fluence (laser beam and flashlamp), large wavefront correction range, wavefront temporal bandwidth, temperature and humidity variations, cleanliness requirements, and exception handling requirements (e.g. wavefront out-of-limits conditions).

Study of irradiation induced surface pattern and structural changes in Inconel 718 alloy

NASA Astrophysics Data System (ADS)

Wan, Hao; Si, Naichao; Zhao, Zhenjiang; Wang, Jian; Zhang, Yifei

2018-05-01

Helium ions irradiation induced surface pattern and structural changes of Inconel 718 alloy were studied with the combined utilization of atomic force microscopy (AFM), x-ray diffraction (XRD) and transmission electron microscopy (TEM). In addition, SRIM-2013 software was used to calculate the sputtering yield and detailed collision events. The result shows that, irradiation dose play an important role in altering the pattern of the surface. Enhanced irradiation aggravated the surface etching and increased the surface roughness. In ion irradiated layer, large amount of interstitials, vacancies and defect sinks were produced. Moreover, in samples with increasing dose irradiation, the dependence of interplanar spacing variation due to point defects clustering on sink density was discussed.

Milk fat depression in dairy ewes fed fish oil: Might differences in rumen biohydrogenation, fermentation, or bacterial community explain the individual variation?

PubMed

Frutos, P; Toral, P G; Belenguer, A; Hervás, G

2018-07-01

Dairy ewes show large individual variation in the extent of diet-induced milk fat depression (MFD) but reasons behind this variability remain uncertain. Previous results offered no convincing support for these differences being related to relevant changes in the milk fatty acid (FA) profile, including potentially antilipogenic FA, or in the transcript abundance of candidate genes involved in mammary lipogenesis. Therefore, we hypothesized that alterations in the processes of rumen biohydrogenation and fermentation, as well as in the bacterial community structure, might account for individual variation in fish oil-induced MFD severity. To test this explanation, 15 ewes received a total mixed ration without lipid supplementation (control; n = 5) or supplemented with 20 g of fish oil/kg of dry matter [10 animals divided into those showing a strong (RESPON+; -25.4%; n = 5) or a mild (RESPON-; -7.7%; n = 5) decrease in milk fat concentration] for 5 wk. Rumen fermentation parameters, biohydrogenation metabolites, and bacterial structure and diversity were analyzed in rumen samples collected before and after treatments. Although the fish oil supplementation increased the concentration of demonstrated or putative antilipogenic FA (e.g., cis-9 16:1, cis-11 18:1, or trans-10,cis-12 CLA), surprisingly, none of them differed significantly in relation to the extent of MFD (i.e., between RESPON- and RESPON+), and this was the case only for a few minor FA (e.g., cis-6+7 16:1 or 17:0 anteiso). Changes in total volatile FA, acetate, and propionate concentrations were associated with MFD severity, with higher decreases in more susceptible animals. Individual responses were not related to shifts in rumen bacterial structure but some terminal restriction fragments compatible with Clostridiales, Ruminococcaceae, Lachnospiraceae, and Succiniclasticum showed greater abundances in RESPON-, whereas some others that may correspond to Prevotella, Mogibacterium, and Quinella-related spp. were more abundant in RESPON+. Overall, the results suggest that individual variation in MFD severity in dairy ewes fed fish oil cannot be fully explained by differences in the processes of rumen biohydrogenation and fermentation or in the bacterial community, and further research would be necessary to elucidate the large variability in the responsiveness to MFD-inducing marine lipids. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Field observations of seismic velocity changes caused by shaking-induced damage and healing due to mesoscopic nonlinearity

NASA Astrophysics Data System (ADS)

Gassenmeier, M.; Sens-Schönfelder, C.; Eulenfeld, T.; Bartsch, M.; Victor, P.; Tilmann, F.; Korn, M.

2016-03-01

To investigate temporal seismic velocity changes due to earthquake related processes and environmental forcing in Northern Chile, we analyse 8 yr of ambient seismic noise recorded by the Integrated Plate Boundary Observatory Chile (IPOC). By autocorrelating the ambient seismic noise field measured on the vertical components, approximations of the Green's functions are retrieved and velocity changes are measured with Coda Wave Interferometry. At station PATCX, we observe seasonal changes in seismic velocity caused by thermal stress as well as transient velocity reductions in the frequency range of 4-6 Hz. Sudden velocity drops occur at the time of mostly earthquake-induced ground shaking and recover over a variable period of time. We present an empirical model that describes the seismic velocity variations based on continuous observations of the local ground acceleration. The model assumes that not only the shaking of large earthquakes causes velocity drops, but any small vibrations continuously induce minor velocity variations that are immediately compensated by healing in the steady state. We show that the shaking effect is accumulated over time and best described by the integrated envelope of the ground acceleration over the discretization interval of the velocity measurements, which is one day. In our model, the amplitude of the velocity reduction as well as the recovery time are proportional to the size of the excitation. This model with two free scaling parameters fits the data of the shaking induced velocity variation in remarkable detail. Additionally, a linear trend is observed that might be related to a recovery process from one or more earthquakes before our measurement period. A clear relationship between ground shaking and induced velocity reductions is not visible at other stations. We attribute the outstanding sensitivity of PATCX to ground shaking and thermal stress to the special geological setting of the station, where the subsurface material consists of relatively loose conglomerate with high pore volume leading to a stronger nonlinearity compared to the other IPOC stations.

Variation of brine compositions resulting from flow from matrix or fracture permeability, investigated by high pressure laboratory experiments

NASA Astrophysics Data System (ADS)

Poszwa, A. C.; Coleman, M. L.; Pouya, A.; Ader, M.; Bounenni, A.

2003-04-01

Planning oil production from a chalk reservoir oilfield is difficult because the matrix usually has low permeability despite its high porosity. Most oil is thought to come from fracture porosity but the matrix contribution should increase as compaction occurs during production. To better understand the respective contributions from matrix and fracture, we studied the geochemical characteristics of fluids using high-pressure brine flow experiments on chalk cores. During the experiment axial load was changed relative to confining pressure to induce fractures and to close them again. We used chlorine stable isotope variations to study fluid pathway, because chlorine is a chemically conservative element in sedimentary systems and its isotopes fractionate only with physical processes like diffusion or adsorption that could occur mainly in the chalk matrix. A first experiment was performed on a very porous chalk from Henley (on-shore UK) and using a low-salinity brine. Large variations of brine Cl isotope composition were observed (from -0.56 to +0.08 per mil). The variations were correlated positively with the brine flux through the chalk and the permeability of the rock, both parameters controlled by the rock fracturing. A second experiment used brine with salinity similar to that of seawater. In this case, chemical and isotopic variations were not significant. From the beginning, the chalk structure seems to have been destroyed very quickly (induced fracture porosity collapsed) possibly because of the fluid nature, so that whatever pressure was applied, the permeability did not change significantly. Using Valhall reservoir chalk (offshore Norwegian North Sea) and fluid half the salinity of seawater in a third experiment, we obtained a large range of permeabilities. Brine isotopic trends were very similar on average to those of the first experiment even though variations were smaller (Cl isotopes from -0.09 to +0.29 per mil) and not significantly correlated simply to permeability values. The highest isotopic values were in brine flowed through chalk when the permeability was high and fractures opened; the lowest values were in brine flowed through the chalk when its permeability was reduced by closing fractures and increasing the relative contribution from matrix flow where diffusion processes fractionated chlorine isotopes. From this work it seems that the relative contributions from fracture and matrix permeability in reservoirs can be estimated from the geochemical compositions of brines that flowed from them.

Simulation of Surface Pressure Induced by Vortex/Body Interaction

NASA Astrophysics Data System (ADS)

He, M.; Islam, M.; Veitch, B.; Bose, N.; Colbourne, M. B.; Liu, P.

When a strong vortical wake impacts a structure, the pressure on the impacted surface sees large variations in its amplitude. This pressure fluctuation is one of the main sources causing severe structural vibration and hydrodynamic noise. Economical and effective prediction methods of the fluctuating pressure are required by engineers in many fields. This paper presents a wake impingement model (WIM) that has been incorporated into a panel method code, Propella, and its applications in simulations of a podded propeller wake impacting on a strut. Simulated strut surface pressure distributions and variations are compared with experimental data in terms of time-averaged components and phase-averaged components. The pressure comparisons show that the calculated results are in a good agreement with experimental data.

Dissecting variation in biomass conversion factors across China's forests: implications for biomass and carbon accounting.

PubMed

Luo, Yunjian; Zhang, Xiaoquan; Wang, Xiaoke; Ren, Yin

2014-01-01

Biomass conversion factors (BCFs, defined as the ratios of tree components (i.e. stem, branch, foliage and root), as well as aboveground and whole biomass of trees to growing stock volume, Mg m-3) are considered as important parameters in large-scale forest biomass carbon estimation. To date, knowledge of possible sources of the variation in BCFs is still limited at large scales. Using our compiled forest biomass dataset of China, we presented forest type-specific values of BCFs, and examined the variation in BCFs in relation to forest type, stand development and environmental factors (climate and soil fertility). BCFs exhibited remarkable variation across forest types, and also were significantly related to stand development (especially growing stock volume). BCFs (except Stem BCF) had significant relationships with mean annual temperature (MAT) and mean annual precipitation (MAP) (P<0.001). Climatic data (MAT and MAP) collectively explained 10.0-25.0% of the variation in BCFs (except Stem BCFs). Moreover, stronger climatic effects were found on BCFs for functional components (i.e. branch, foliage and root) than BCFs for combined components (i.e. aboveground section and whole trees). A general trend for BCFs was observed to decrease and then increase from low to high soil fertility. When qualitative soil fertility and climatic data (MAT and MAP) were combined, they explained 14.1-29.7% of the variation in in BCFs (except Stem BCFs), adding only 4.1-4.9% than climatic data used. Therefore, to reduce the uncertainty induced by BCFs in forest carbon estimates, we should apply values of BCFs for a specified forest type, and also consider climatic and edaphic effects, especially climatic effect, in developing predictive models of BCFs (except Stem BCF).

Dissecting Variation in Biomass Conversion Factors across China’s Forests: Implications for Biomass and Carbon Accounting

PubMed Central

Wang, Xiaoke; Ren, Yin

2014-01-01

Biomass conversion factors (BCFs, defined as the ratios of tree components (i.e. stem, branch, foliage and root), as well as aboveground and whole biomass of trees to growing stock volume, Mg m−3) are considered as important parameters in large-scale forest biomass carbon estimation. To date, knowledge of possible sources of the variation in BCFs is still limited at large scales. Using our compiled forest biomass dataset of China, we presented forest type-specific values of BCFs, and examined the variation in BCFs in relation to forest type, stand development and environmental factors (climate and soil fertility). BCFs exhibited remarkable variation across forest types, and also were significantly related to stand development (especially growing stock volume). BCFs (except Stem BCF) had significant relationships with mean annual temperature (MAT) and mean annual precipitation (MAP) (P<0.001). Climatic data (MAT and MAP) collectively explained 10.0–25.0% of the variation in BCFs (except Stem BCFs). Moreover, stronger climatic effects were found on BCFs for functional components (i.e. branch, foliage and root) than BCFs for combined components (i.e. aboveground section and whole trees). A general trend for BCFs was observed to decrease and then increase from low to high soil fertility. When qualitative soil fertility and climatic data (MAT and MAP) were combined, they explained 14.1–29.7% of the variation in in BCFs (except Stem BCFs), adding only 4.1–4.9% than climatic data used. Therefore, to reduce the uncertainty induced by BCFs in forest carbon estimates, we should apply values of BCFs for a specified forest type, and also consider climatic and edaphic effects, especially climatic effect, in developing predictive models of BCFs (except Stem BCF). PMID:24728222

How does ocean seasonality drive habitat preferences of highly mobile top predators? Part II: The eastern North-Atlantic

NASA Astrophysics Data System (ADS)

Lambert, C.; Pettex, E.; Dorémus, G.; Laran, S.; Stéphan, E.; Canneyt, O. Van; Ridoux, V.

2017-07-01

Marine ecosystems are characterised by strong heterogeneity and variability, both spatially and temporally. In particular, seasonal variations may lead to severe constraints for predators which have to cope with these variations, for example through migration to avoid unfavourable seasons, or adaptation to local modification of the ecosystem. In the Bay of Biscay and English Channel, ecosystem seasonality is well marked, especially over the shelf. Cetacean and seabird communities within the Bay of Biscay, Celtic Sea and English Channel were studied during aerial surveys conducted in winter 2011-2012 and summer 2012, following a strip-transect methodology deployed from the coast to oceanic waters. We explored seasonal variations of habitat preferences of four cetacean and six seabird groups through Generalised Additive Models, using physiographic variables and weekly- and monthly-averaged oceanographic predictors for both seasons. Our results provided the first overview at such a large scale of the variation of habitat preferences in response to the seasonality of the ocean by seabirds in that region, at such a large scale. Habitat models resulted in explained deviances from 13 to 55%. Predators answered the seasonality of their environment in different ways. Long-finned pilot whales and Risso's dolphins were the only studied group exhibiting no habitat variations between seasons, targeting the shelf break throughout the year. The other groups modulated their habitat preferences between seasons to optimise the compromise between the ocean seasonal variations and their own constraints: common and striped dolphins, bottlenose dolphins and harbour porpoises for cetaceans; northern gannets, auks, northern fulmars and kittiwakes for seabirds. For shearwaters, the seasonality had an extreme impact, inducing a complete absence from the region during the unfavourable season.

A model for seasonal changes in GPS positions and seismic wave speeds due to thermoelastic and hydrologic variations

USGS Publications Warehouse

Tsai, V.C.

2011-01-01

It is known that GPS time series contain a seasonal variation that is not due to tectonic motions, and it has recently been shown that crustal seismic velocities may also vary seasonally. In order to explain these changes, a number of hypotheses have been given, among which thermoelastic and hydrology-induced stresses and strains are leading candidates. Unfortunately, though, since a general framework does not exist for understanding such seasonal variations, it is currently not possible to quickly evaluate the plausibility of these hypotheses. To fill this gap in the literature, I generalize a two-dimensional thermoelastic strain model to provide an analytic solution for the displacements and wave speed changes due to either thermoelastic stresses or hydrologic loading, which consists of poroelastic stresses and purely elastic stresses. The thermoelastic model assumes a periodic surface temperature, and the hydrologic models similarly assume a periodic near-surface water load. Since all three models are two-dimensional and periodic, they are expected to only approximate any realistic scenario; but the models nonetheless provide a quantitative framework for estimating the effects of thermoelastic and hydrologic variations. Quantitative comparison between the models and observations is further complicated by the large uncertainty in some of the relevant parameters. Despite this uncertainty, though, I find that maximum realistic thermoelastic effects are unlikely to explain a large fraction of the observed annual variation in a typical GPS displacement time series or of the observed annual variations in seismic wave speeds in southern California. Hydrologic loading, on the other hand, may be able to explain a larger fraction of both the annual variations in displacements and seismic wave speeds. Neither model is likely to explain all of the seismic wave speed variations inferred from observations. However, more definitive conclusions cannot be made until the model parameters are better constrained. Copyright ?? 2011 by the American Geophysical Union.

Statistical Maps of Ground Magnetic Disturbance Derived from Global Geospace Models

NASA Astrophysics Data System (ADS)

Rigler, E. J.; Wiltberger, M. J.; Love, J. J.

2017-12-01

Electric currents in space are the principal driver of magnetic variations measured at Earth's surface. These in turn induce geoelectric fields that present a natural hazard for technological systems like high-voltage power distribution networks. Modern global geospace models can reasonably simulate large-scale geomagnetic response to solar wind variations, but they are less successful at deterministic predictions of intense localized geomagnetic activity that most impacts technological systems on the ground. Still, recent studies have shown that these models can accurately reproduce the spatial statistical distributions of geomagnetic activity, suggesting that their physics are largely correct. Since the magnetosphere is a largely externally driven system, most model-measurement discrepancies probably arise from uncertain boundary conditions. So, with realistic distributions of solar wind parameters to establish its boundary conditions, we use the Lyon-Fedder-Mobarry (LFM) geospace model to build a synthetic multivariate statistical model of gridded ground magnetic disturbance. From this, we analyze the spatial modes of geomagnetic response, regress on available measurements to fill in unsampled locations on the grid, and estimate the global probability distribution of extreme magnetic disturbance. The latter offers a prototype geomagnetic "hazard map", similar to those used to characterize better-known geophysical hazards like earthquakes and floods.

Study of Magnetic Field Spatial Variations in the Southern Hemisphere's Low Latitudes due to Different Interplanetary Structures Using the 3-D MHD SWMF/BATSRUS Model

NASA Astrophysics Data System (ADS)

Souza, V. M. C. E. S.; Jauer, P. R.; Alves, L. R.; Padilha, A. L.; Padua, M. B.; Vitorello, I.; Alves, M. V.; Da Silva, L. A.

2017-12-01

Interplanetary structures such as Coronal Mass Ejections (CME), Shocks, Corotating Interaction Regions (CIR) and Magnetic Clouds (MC) interfere directly on Space Weather conditions and can cause severe and intense disturbances in the Earth's magnetic field as measured in space and on the ground. During magnetically disturbed periods characterized by world-wide, abrupt variations of the geomagnetic field, large and intense current systems can be induced and amplified within the Earth even at low latitudes. Such current systems are known as geomagnetically induced currents (GIC) and can cause damage to power transmission lines, transformers and the degradation of pipelines. As part of an effort to estimate GIC intensities throughout the low to equatorial latitudes of the Brazilian territory, we used the 3-D MHD SWMF/BATSRUS code to estimate spatial variations of the geomagnetic field during periods when the magnetosphere is under the influence of CME and MC structures. Specifically, we used the CalcDeltaB tool (Rastatter et al., Space Weather, 2014) to provide a proxy for the spatial variations of the geomagnetic field, with a 1 minute cadence, at 31 virtual magnetometer stations located in the proposed study region. The stations are spatially arranged in a two-dimensional network with each station being 5 degrees apart in latitude and longitude. In a preliminary analysis, we found that prior to the arrival of each interplanetary structure, there is no appreciable variation in the components of the geomagnetic field between the virtual stations. However, when the interplanetary structures reach the magnetosphere, each station perceives the magnetic field variation differently, so that it is not possible to use a single station to represent the magnetic field perturbation throughout the Brazilian region. We discuss the minimum number and spacing between stations to adequately detail the geomagnetic field variations in this region.

Impacts of interactive dust and its direct radiative forcing on interannual variations of temperature and precipitation in winter over East Asia: Impacts of Dust on IAVs of Temperature

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lou, Sijia; Russell, Lynn M.; Yang, Yang

We used 150-year pre-industrial simulations of the Community Earth System Model (CESM) to quantify the impacts of interactively-modeled dust emissions on the interannual variations of temperature and precipitation over East Asia during the East Asian Winter Monsoon (EAWM) season. The simulated December-January-February dust column burden and dust optical depth are lower over northern China in the strongest EAWM years than those of the weakest years, with regional mean values lower by 38.3% and 37.2%, respectively. The decrease in dust over the dust source regions (the Taklamakan and Gobi Deserts) and the downwind region (such as the North China Plain) leadsmore » to an increase in direct radiative forcing (RF) both at the surface and top of atmosphere by up to 1.5 and 0.75 W m-2, respectively. The effects of EAWM-related variations in surface winds, precipitation and their effects on dust emissions and wet removal contribute about 67% to the total dust-induced variations of direct RF at the surface and partly offset the cooling that occurs with the EAWM strengthening by heating the surface. The variations of surface air temperature induced by the changes in wind and dust emissions increase by 0.4-0.6 K over eastern coastal China, northeastern China, and Japan, which weakens the impact of EAWM on surface air temperature by 3–18% in these regions. The warming results from the combined effects of changes in direct RF and easterly wind anomalies that bring warm air from the ocean to these regions. Moreover, the feedback of the changes in wind on dust emissions weakens the variations of the sea level pressure gradient on the Siberian High while enhancing the Maritime Continent Low. Therefore, cold air is prevented from being transported from Siberia, Kazakhstan, western and central China to the western Pacific Ocean and decreases surface air temperature by 0.6 K and 2 K over central China and the Tibetan Plateau, respectively. Over eastern coastal China, the variations of large-scale precipitation induced by the feedback of EAWM-related changes in wind on dust emissions increase by 10-30% in winter because of the increase in surface air temperature and the anomalous circulation.« less

The role of sediment supply in large-scale stratigraphic architecture of ancient Gilbert-type deltas (Pliocene Siena-Radicofani Basin, Italy)

NASA Astrophysics Data System (ADS)

Martini, Ivan; Ambrosetti, Elisa; Sandrelli, Fabio

2017-04-01

Aggradation, progradation and retrogradation are the main patterns that define the large-scale architecture of Gilbert-type deltas. These patterns are governed by the ratio between the variation in accommodation space and sediment supply experienced during delta growth. Sediment supply variations are difficult to estimate in ancient settings; hence, it is rarely possible to assess its significance in the large-scale stratigraphic architecture of Gilbert-type deltas. This paper presents a stratigraphic analysis of a Pliocene deltaic complex composed of two coeval and narrowly spaced deltaic branches. The two branches recorded the same tectonic- and climate-induced accommodation space variations. As a result, this deltaic complex represents a natural laboratory for testing the effects of sediment supply variations on the stratigraphic architecture of Gilbert-type deltas. The field data suggest that a sediment supply which is able to counteract the accommodation generated over time promotes the aggradational/progradational attitude of Gilbert-type deltas, as well as the development of thick foreset deposits. By contrast, if the sediment supply is not sufficient for counterbalancing the generated accommodation, an aggradational/retrogradational stratigraphic architecture is promoted. In this case, the deltaic system is forced to withdraw during the different phases of generation of accommodation, with the subsequent flooding of previously deposited sub-horizontal topset deposits (i.e., the delta plain). The subsequent deltaic progradation occurs above these deposits and, consequently, the available space for foresets growth is limited to the water depth between the base-level and the older delta plain. This leads to the vertical stacking of relatively thin deltaic deposits with an overall aggradatational/retrogradational attitude.

Sun-induced fluorescence - a new probe of photosynthesis: First maps from the imaging spectrometer HyPlant.

PubMed

Rascher, U; Alonso, L; Burkart, A; Cilia, C; Cogliati, S; Colombo, R; Damm, A; Drusch, M; Guanter, L; Hanus, J; Hyvärinen, T; Julitta, T; Jussila, J; Kataja, K; Kokkalis, P; Kraft, S; Kraska, T; Matveeva, M; Moreno, J; Muller, O; Panigada, C; Pikl, M; Pinto, F; Prey, L; Pude, R; Rossini, M; Schickling, A; Schurr, U; Schüttemeyer, D; Verrelst, J; Zemek, F

2015-12-01

Variations in photosynthesis still cause substantial uncertainties in predicting photosynthetic CO2 uptake rates and monitoring plant stress. Changes in actual photosynthesis that are not related to greenness of vegetation are difficult to measure by reflectance based optical remote sensing techniques. Several activities are underway to evaluate the sun-induced fluorescence signal on the ground and on a coarse spatial scale using space-borne imaging spectrometers. Intermediate-scale observations using airborne-based imaging spectroscopy, which are critical to bridge the existing gap between small-scale field studies and global observations, are still insufficient. Here we present the first validated maps of sun-induced fluorescence in that critical, intermediate spatial resolution, employing the novel airborne imaging spectrometer HyPlant. HyPlant has an unprecedented spectral resolution, which allows for the first time quantifying sun-induced fluorescence fluxes in physical units according to the Fraunhofer Line Depth Principle that exploits solar and atmospheric absorption bands. Maps of sun-induced fluorescence show a large spatial variability between different vegetation types, which complement classical remote sensing approaches. Different crop types largely differ in emitting fluorescence that additionally changes within the seasonal cycle and thus may be related to the seasonal activation and deactivation of the photosynthetic machinery. We argue that sun-induced fluorescence emission is related to two processes: (i) the total absorbed radiation by photosynthetically active chlorophyll; and (ii) the functional status of actual photosynthesis and vegetation stress. © 2015 John Wiley & Sons Ltd.

Calibration approach for extremely variable laser induced plasmas and a strategy to reduce the matrix effect in general

NASA Astrophysics Data System (ADS)

Lazic, V.; De Ninno, A.

2017-11-01

The laser induced plasma spectroscopy was applied on particles attached on substrate represented by a silica wafer covered with a thin oil film. The substrate itself weakly interacts with a ns Nd:YAG laser (1064 nm) while presence of particles strongly enhances the plasma emission, here detected by a compact spectrometer array. Variations of the sample mass from one laser spot to another exceed one order of magnitude, as estimated by on-line photography and the initial image calibration for different sample loadings. Consequently, the spectral lines from particles show extreme intensity fluctuations from one sampling point to another, between the detection threshold and the detector's saturation in some cases. In such conditions the common calibration approach based on the averaged spectra, also when considering ratios of the element lines i.e. concentrations, produces errors too large for measuring the sample compositions. On the other hand, intensities of an analytical and the reference line from single shot spectra are linearly correlated. The corresponding slope depends on the concentration ratio and it is weakly sensitive to fluctuations of the plasma temperature inside the data set. A use of the slopes for constructing the calibration graphs significantly reduces the error bars but it does not eliminate the point scattering caused by the matrix effect, which is also responsible for large differences in the average plasma temperatures among the samples. Well aligned calibration points were obtained after identifying the couples of transitions less sensitive to variations of the plasma temperature, and this was achieved by simple theoretical simulations. Such selection of the analytical lines minimizes the matrix effect, and together with the chosen calibration approach, allows to measure the relative element concentrations even in highly unstable laser induced plasmas.

Largely Increased Nitrous Oxide Emission from Global Livestock Sector during 1860-2014: A geospatial-temporal analysis

NASA Astrophysics Data System (ADS)

Zhang, B.; Tian, H.; Xu, R.; Yang, J.; Pan, S.; Chen, G.

2017-12-01

The atmospheric concentration of nitrous oxide (N2O), one of major greenhouse gases, has increased over 121% compared with the preindustrial level, and most of the increase arises from anthropogenic activities. The shift of human diet and the ever-increasing human population pose a huge pressure on the demand of growing livestock population. Of particular interest is how changes in livestock population could alter the environmental health through emissions of greenhouse gases, especially nitrous oxide. Moreover, the quantification of livestock induced nitrous oxide emission with global coverage that characterize consecutive inter-annual variations during historical period is lacking. Thus, in this study, we tried to quantify the magnitude, temporal and spatial variations of livestock-induced nitrous oxide emission during 1860-2014. We include both direct and indirect emission of nitrous oxide from managed soils. We also further analyze the relative contribution of major livestock types on nitrous oxide emission. The results indicated that there was a significant increasing trend of livestock-induced nitrous oxide during 1860-2014. Changes in nitrous oxide emission exhibited highly spatial variability and concentrated in several hotspots during the study period. Less meat consumption is not only good for human health, but also favors for environment-friendly development.

Land cover variation and West Nile virus prevalence: Patterns, processes, and implications for disease control

USGS Publications Warehouse

Ezenwa, V.O.; Milheim, L.E.; Coffey, M.F.; Godsey, M.S.; King, R.J.; Guptill, S.C.

2007-01-01

Identifying links between environmental variables and infectious disease risk is essential to understanding how human-induced environmental changes will effect the dynamics of human and wildlife diseases. Although land cover change has often been tied to spatial variation in disease occurrence, the underlying factors driving the correlations are often unknown, limiting the applicability of these results for disease prevention and control. In this study, we described associations between land cover composition and West Nile virus (WNV) infection prevalence, and investigated three potential processes accounting for observed patterns: (1) variation in vector density; (2) variation in amplification host abundance; and (3) variation in host community composition. Interestingly, we found that WNV infection rates among Culex mosquitoes declined with increasing wetland cover, but wetland area was not significantly associated with either vector density or amplification host abundance. By contrast, wetland area was strongly correlated with host community composition, and model comparisons suggested that this factor accounted, at least partially, for the observed effect of wetland area on WNV infection risk. Our results suggest that preserving large wetland areas, and by extension, intact wetland bird communities, may represent a valuable ecosystem-based approach for controlling WNV outbreaks. ?? Mary Ann Liebert, Inc.

Anthocyanin inhibits propidium iodide DNA fluorescence in Euphorbia pulcherrima: implications for genome size variation and flow cytometry.

PubMed

Bennett, Michael D; Price, H James; Johnston, J Spencer

2008-04-01

Measuring genome size by flow cytometry assumes direct proportionality between nuclear DNA staining and DNA amount. By 1997 it was recognized that secondary metabolites may affect DNA staining, thereby causing inaccuracy. Here experiments are reported with poinsettia (Euphorbia pulcherrima) with green leaves and red bracts rich in phenolics. DNA content was estimated as fluorescence of propidium iodide (PI)-stained nuclei of poinsettia and/or pea (Pisum sativum) using flow cytometry. Tissue was chopped, or two tissues co-chopped, in Galbraith buffer alone or with six concentrations of cyanidin-3-rutinoside (a cyanidin-3-rhamnoglucoside contributing to red coloration in poinsettia). There were large differences in PI staining (35-70 %) between 2C nuclei from green leaf and red bract tissue in poinsettia. These largely disappeared when pea leaflets were co-chopped with poinsettia tissue as an internal standard. However, smaller (2.8-6.9 %) differences remained, and red bracts gave significantly lower 1C genome size estimates (1.69-1.76 pg) than green leaves (1.81 pg). Chopping pea or poinsettia tissue in buffer with 0-200 microm cyanidin-3-rutinoside showed that the effects of natural inhibitors in red bracts of poinsettia on PI staining were largely reproduced in a dose-dependent way by this anthocyanin. Given their near-ubiquitous distribution, many suspected roles and known affects on DNA staining, anthocyanins are a potent, potential cause of significant error variation in genome size estimations for many plant tissues and taxa. This has important implications of wide practical and theoretical significance. When choosing genome size calibration standards it seems prudent to select materials producing little or no anthocyanin. Reviewing the literature identifies clear examples in which claims of intraspecific variation in genome size are probably artefacts caused by natural variation in anthocyanin levels or correlated with environmental factors known to induce variation in pigmentation.

Earthquakes induced by fluid injection and explosion

USGS Publications Warehouse

Healy, J.H.; Hamilton, R.M.; Raleigh, C.B.

1970-01-01

Earthquakes generated by fluid injection near Denver, Colorado, are compared with earthquakes triggered by nuclear explosion at the Nevada Test Site. Spatial distributions of the earthquakes in both cases are compatible with the hypothesis that variation of fluid pressure in preexisting fractures controls the time distribution of the seismic events in an "aftershock" sequence. We suggest that the fluid pressure changes may also control the distribution in time and space of natural aftershock sequences and of earthquakes that have been reported near large reservoirs. ?? 1970.

CRUSTAL FAILURE DURING BINARY INSPIRAL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Penner, A. J.; Andersson, N.; Jones, D. I.

2012-04-20

We present the first fully relativistic calculations of the crustal strain induced in a neutron star by a binary companion at the late stages of inspiral, employing realistic equations of state for the fluid core and the solid crust. We show that while the deep crust is likely to fail only shortly before coalescence, there is a large variation in elastic strain, with the outermost layers failing relatively early on in the inspiral. We discuss the significance of the results for both electromagnetic and gravitational-wave astronomy.

Navigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis

PubMed Central

Li, Dapeng; Baldwin, Ian T.; Gaquerel, Emmanuel

2015-01-01

Natural variation can be extremely useful in unraveling the determinants of phenotypic trait evolution but has rarely been analyzed with unbiased metabolic profiling to understand how its effects are organized at the level of biochemical pathways. Native populations of Nicotiana attenuata, a wild tobacco species, have been shown to be highly genetically diverse for traits important for their interactions with insects. To resolve the chemodiversity existing in these populations, we developed a metabolomics and computational pipeline to annotate leaf metabolic responses to Manduca sexta herbivory. We selected seeds from 43 accessions of different populations from the southwestern United States—including the well-characterized Utah 30th generation inbred accession—and grew 183 plants in the glasshouse for standardized herbivory elicitation. Metabolic profiles were generated from elicited leaves of each plant using a high-throughput ultra HPLC (UHPLC)-quadrupole TOFMS (qTOFMS) method, processed to systematically infer covariation patterns among biochemically related metabolites, as well as unknown ones, and finally assembled to map natural variation. Navigating this map revealed metabolic branch-specific variations that surprisingly only partly overlapped with jasmonate accumulation polymorphisms and deviated from canonical jasmonate signaling. Fragmentation analysis via indiscriminant tandem mass spectrometry (idMS/MS) was conducted with 10 accessions that spanned a large proportion of the variance found in the complete accession dataset, and compound spectra were computationally assembled into spectral similarity networks. The biological information captured by this networking approach facilitates the mining of the mass spectral data of unknowns with high natural variation, as demonstrated by the annotation of a strongly herbivory-inducible phenolic derivative, and can guide pathway analysis. PMID:26170304

Heritability of vaccine-induced measles neutralizing antibody titers.

PubMed

Schaid, Daniel J; Haralambieva, Iana H; Larrabee, Beth R; Ovsyannikova, Inna G; Kennedy, Richard B; Poland, Gregory A

2017-03-07

Understanding how genetics influences inter-individual variation of antibody titers in response to measles vaccination is vital to understanding possible sources of vaccine failure as well as improved vaccine development. Although it is recognized that both the human leukocyte antigen (HLA) genes and the immunoglobulin allotype genes play significant roles in immune response, there is significant variation in antibody titers that is not explained by these genes. To obtain a more complete estimate of the role of the entire genome, we used a large panel of single nucleotide polymorphisms to estimate the heritability of antibody response to measles vaccine. Based on 935 subjects with European ancestry, we estimated the heritability to be 49% (standard error 0.17). We also estimated the heritability attributable to each chromosome, and found a large range in chromosome-specific heritabilities. Notably, chromosome 1 had the largest estimate (28%), while chromosome 6, which harbors HLA, had an estimated heritability of 13%. Compared with a prior study of twins in the same community, which resulted in a heritability estimate of 88.5%, our study suggests there are either many rare genetic variants, or many common genetic variants of small effect sizes that contribute to variations of antibody titers in response to measles vaccine. Copyright © 2017 Elsevier Ltd. All rights reserved.

Depth of origin of ocean-circulation-induced magnetic signals

NASA Astrophysics Data System (ADS)

Irrgang, Christopher; Saynisch-Wagner, Jan; Thomas, Maik

2018-01-01

As the world ocean moves through the ambient geomagnetic core field, electric currents are generated in the entire ocean basin. These oceanic electric currents induce weak magnetic signals that are principally observable outside of the ocean and allow inferences about large-scale oceanic transports of water, heat, and salinity. The ocean-induced magnetic field is an integral quantity and, to first order, it is proportional to depth-integrated and conductivity-weighted ocean currents. However, the specific contribution of oceanic transports at different depths to the motional induction process remains unclear and is examined in this study. We show that large-scale motional induction due to the general ocean circulation is dominantly generated by ocean currents in the upper 2000 m of the ocean basin. In particular, our findings allow relating regional patterns of the oceanic magnetic field to corresponding oceanic transports at different depths. Ocean currents below 3000 m, in contrast, only contribute a small fraction to the ocean-induced magnetic signal strength with values up to 0.2 nT at sea surface and less than 0.1 nT at the Swarm satellite altitude. Thereby, potential satellite observations of ocean-circulation-induced magnetic signals are found to be likely insensitive to deep ocean currents. Furthermore, it is shown that annual temporal variations of the ocean-induced magnetic field in the region of the Antarctic Circumpolar Current contain information about sub-surface ocean currents below 1000 m with intra-annual periods. Specifically, ocean currents with sub-monthly periods dominate the annual temporal variability of the ocean-induced magnetic field.

SOAP 2.0: a tool to estimate the photometric and radial velocity variations induced by stellar spots and plages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dumusque, X.; Boisse, I.; Santos, N. C., E-mail: xdumusque@cfa.harvard.edu

2014-12-01

This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the casemore » of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i ≤8 km s{sup –1}. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation.« less

Using low-risk factors to generate non-integrated human induced pluripotent stem cells from urine-derived cells.

PubMed

Wang, Linli; Chen, Yuehua; Guan, Chunyan; Zhao, Zhiju; Li, Qiang; Yang, Jianguo; Mo, Jian; Wang, Bin; Wu, Wei; Yang, Xiaohui; Song, Libing; Li, Jun

2017-11-02

Because the lack of an induced pluripotent stem cell (iPSC) induction system with optimal safety and efficiency limits the application of these cells, development of such a system is important. To create such an induction system, we screened a variety of reprogrammed plasmid combinations and multiple compounds and then verified the system's feasibility using urine cells from different individuals. We also compared large-scale iPSC chromosomal variations and expression of genes associated with genomic stability between this system and the traditional episomal system using karyotype and quantitative reverse transcription polymerase chain reaction analyses. We developed a high-efficiency episomal system, the 6F/BM1-4C system, lacking tumorigenic factors for human urine-derived cell (hUC) reprogramming. This system includes six low-risk factors (6F), Oct4, Glis1, Klf4, Sox2, L-Myc, and the miR-302 cluster. Transfected hUCs were treated with four compounds (4C), inhibitor of lysine-demethylase1, methyl ethyl ketone, glycogen synthase kinase 3 beta, and histone deacetylase, within a short time period. Comparative analysis revealed significantly decreased chromosomal variation in iPSCs and significantly increased Sirt1 expression compared with iPSCs induced using the traditional episomal system. The 6F/BM1-4C system effectively induces reprogramming of urine cells in samples obtained from different individuals. iPSCs induced using the 6F/BM1-4C system are more stable at the cytogenetic level and have potential value for clinical application.

Direct EUV/X-Ray Modulation of the Ionosphere During the August 2017 Total Solar Eclipse

NASA Astrophysics Data System (ADS)

Mrak, Sebastijan; Semeter, Joshua; Drob, Douglas; Huba, J. D.

2018-05-01

The great American total solar eclipse of 21 August 2017 offered a fortuitous opportunity to study the response of the atmosphere and ionosphere using a myriad of ground instruments. We have used the network of U.S. Global Positioning System receivers to examine perturbations in maps of ionospheric total electron content (TEC). Coherent large-scale variations in TEC have been interpreted by others as gravity wave-induced traveling ionospheric disturbances. However, the solar disk had two active regions at that time, one near the center of the disk and one at the edge, which resulted in an irregular illumination pattern in the extreme ultraviolet (EUV)/X-ray bands. Using detailed EUV occultation maps calculated from the National Aeronautics and Space Administration Solar Dynamics Observatory Atmospheric Imaging Assembly images, we show excellent agreement between TEC perturbations and computed gradients in EUV illumination. The results strongly suggest that prominent large-scale TEC disturbances were consequences of direct EUV modulation, rather than gravity wave-induced traveling ionospheric disturbances.

Decadal-period external magnetic field variations resolved with eigenanalysis

NASA Astrophysics Data System (ADS)

Shore, Robert; Whaler, Kathryn; Macmillan, Susan; Beggan, Ciarán; Velímský, Jakub; Olsen, Nils

2017-04-01

Variations in the magnetic field at and above the Earth's surface permeate the interior of our planet, and can be used to determine the electrical conductivity of the mantle. Presently, the annual and semi-annual period fields induced by magnetospheric and ionospheric currents, suitable to estimate mantle conductivity in the approximate depth range 1,200-2,000 km, are subject to large uncertainty since they overlap with the periods on which the core field also changes significantly. It is timely to obtain an improved determination of the spatial geometry of the external, inducing, fields in order to better separate their internal, induced, part from that generated in the core. We apply the method of Empirical Orthogonal Functions (EOFs) to a dataset of ground-based magnetic observatory hourly means in order to decompose the external magnetic field during quiet times over a full 11-year solar cycle into its modes of maximum variance. This allows us to assess the spatial structures and magnitude changes of its dominant spatio-temporal patterns. Specifically, our focus is on isolating the long period external inducing fields as they penetrate to the depths of the mantle where the conductivity is least constrained. We expand ground-based measurements in the inertial local-time frame to produce spherical harmonic models of the dominant long period signals isolated by the EOF method. Whilst the ring current dominates the decomposition, we show that an annual and a semi-annual oscillation are important in describing the full inducing field. Each of these terms exhibits a modulation from the 11-year solar cycle. In summary, the most important harmonic in the description of the inducing fields is P10, followed by P21. There are lesser but still significant contributions from the P11 and P20 harmonics.

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

PubMed Central

Rubbi, Carlos P.; Milner, Jo

2003-01-01

p53 protects against cancer through its capacity to induce cell cycle arrest or apoptosis under a large variety of cellular stresses. It is not known how such diversity of signals can be integrated by a single molecule. However, the literature reveals that a common denominator in all p53-inducing stresses is nucleolar disruption. We thus postulated that the impairment of nucleolar function might stabilize p53 by preventing its degradation. Using micropore irradiation, we demonstrate that large amounts of nuclear DNA damage fail to stabilize p53 unless the nucleolus is also disrupted. Forcing nucleolar disruption by anti-upstream binding factor (UBF) microinjection (in the absence of DNA damage) also causes p53 stabilization. We propose that the nucleolus is a stress sensor responsible for maintenance of low levels of p53, which are automatically elevated as soon as nucleolar function is impaired in response to stress. Our model integrates all known p53-inducing agents and also explains cell cycle-related variations in p53 levels which correlate with established phases of nucleolar assembly/disassembly through the cell cycle. PMID:14609953

Transient Interfacial Phenomena in Miscible Polymer Systems (TIPMPS)

NASA Technical Reports Server (NTRS)

Pojman, John A.; Bessonov, Nicholas; Volpert, Vitaly; Wilke, Hermann

2003-01-01

Almost one hundred years ago Korteweg published a theory of how stresses could be induced in miscible fluids by concentration gradients, causing phenomena that would appear to be the same as with immiscible fluids. Miscible fluids could manifest a transient or effective interfacial tension (EIT). To this day, there has been no definitive experiment to confirm Korteweg's model but numerous fascinating and suggestive experiments have been reported. The goal of TIPMPS is to answer the question: Can concentration and temperature gradients in miscible materials induce stresses that cause convection? Many polymer processes involving miscible monomer and polymer systems could be affected by fluid flow and so this work could help understand miscible polymer processing, not only in microgravity, but also on earth. Demonstrating the existence of this phenomenon in miscible fluids will open up a new area of study for materials science. The science objectives of TIPMPS are: (1) Determine if convection can be induced by variation of the width of a miscible interface; (2) Determine if convection can be induced by variation of temperature along a miscible interface; (3) Determine if convection can be induced by variation of conversion along a miscible interface An interface between two miscible fluids can best be created via a spatially-selective photopolymerization of dodecyl acrylate with a photoinitiator, which allows the creation of precise and accurate concentration gradients between polymer and monomer. Optical techniques will be used to measure the refractive index variation caused by the resultant temperature and concentration fields. The viscosity of the polymer will be measured from the increase in the fluorescence of pyrene. Because the large concentration and temperature gradients cause buoyancy-driven convection that prevents the observation of the predicted flows, the experiment must be done in microgravity. In this report, we will consider our efforts to estimate the square gradient parameter, k, and our use of the estimates in modeling of the planned TIPMPS experiments. We developed a model consisting of the heat and diffusion equations with convective terms and of the Navier-Stokes equations with an additional volume force written in the form of the Korteweg stresses arising from nonlocal interaction in the fluid. The fluid's viscosity dependence on polymer conversion and temperature was taken from measurements of poly(dodecyl acrylate). Numerical modeling demonstrated that significant flows would arise for conditions corresponding to the planned experiments.

Discrepancy Between ASTER- and MODIS- Derived Land Surface Temperatures: Terrain Effects

PubMed Central

Liu, Yuanbo; Noumi, Yousuke; Yamaguchi, Yasushi

2009-01-01

The MODerate resolution Imaging Spectroradiometer (MODIS) and the Advanced Spaceborne Thermal Emission Reflection Radiometer (ASTER) are onboard the same satellite platform NASA TERRA. Both MODIS and ASTER offer routine retrieval of land surface temperatures (LSTs), and the ASTER- and MODIS-retrieved LST products have been used worldwide. Because a large fraction of the earth surface consists of mountainous areas, variations in elevation, terrain slope and aspect angles can cause biases in the retrieved LSTs. However, terrain-induced effects are generally neglected in most satellite retrievals, which may generate discrepancy between ASTER and MODIS LSTs. In this paper, we reported the terrain effects on the LST discrepancy with a case examination over a relief area at the Loess Plateau of China. Results showed that the terrain-induced effects were not major, but nevertheless important for the total LST discrepancy. A large local slope did not necessarily lead to a large LST discrepancy. The angle of emitted radiance was more important than the angle of local slope in generating the LST discrepancy. Specifically, the conventional terrain correction may be unsuitable for densely vegetated areas. The distribution of ASTER-to-MODIS emissivity suggested that the terrain correction was included in the generalized split window (GSW) based approach used to rectify MODIS LSTs. Further study should include the classification-induced uncertainty in emissivity for reliable use of satellite-retrieved LSTs over relief areas. PMID:22399955

Modeling the Diurnal Tides in the MLT Region with the Doppler Spread Parameterization of Gravity Waves

NASA Technical Reports Server (NTRS)

Mayr, H. G.; Mengel, J. G.; Chan, K. L.; Trob, D.; Porter, H. C.; Einaudi, Franco (Technical Monitor)

2000-01-01

Special Session: SA03 The mesosphere/lower thermosphere region: Structure, dynamics, composition, and emission. Ground based and satellite observations in the upper mesosphere and lower thermosphere (MLT) reveal large seasonal variations in the horizontal wind fields of the diurnal and semidiurnal tides. To provide an understanding of the observations, we discuss results obtained with our Numerical Spectral Model (NMS) that incorporates the gravity wave Doppler Spread Parameterization (DSP) of Hines. Our model reproduces many of the salient features observed, and we discuss numerical experiments that delineate the important processes involved. Gravity wave momentum deposition and the seasonal variations in the tidal excitation contribute primarily to produce the large equinoctial amplitude maxima in the diurnal tide. Gravity wave induced variations in eddy viscosity, not accounted for in the model, have been shown by Akmaev to be important too. For the semidiurnal tide, with amplitude maximum observed during winter solstice, these processes also contribute, but filtering by the mean zonal circulation is more important. A deficiency of our model is that it cannot reproduce the observed seasonal variations in the phase of the semidiurnal tide, and numerical experiments are being carried out to diagnose the cause and to alleviate this problem. The dynamical components of the upper mesosphere are tightly coupled through non-linear processes and wave filtering, and this may constrain the model and require it to reproduce in detail the observed phenomenology.

Variations in body weight, food intake and body composition after long-term high-fat diet feeding in C57BL/6J Mice

PubMed Central

Yang, Yongbin; Smith, Daniel L.; Keating, Karen D.; Allison, David B.; Nagy, Tim R.

2014-01-01

Objective To investigate the variations in body weight, food intake and body composition of both male and female C57BL/6J mice during a diet-induced obesity (DIO) model with high-fat diet (HFD) feeding. Design and Methods Mice were individually housed and fed ad libitum either a low-fat diet (LFD, 10% calories from fat; n=15 male, n=15 female) or high-fat diet (HFD, 45% calories from fat; n=277 male, n=278 female) from 8 to 43 weeks of age. Body weight, food intake and body composition were routinely measured. Results Body weight was significantly increased with HFD (vs. LFD) in males from week 14 (p=0.0221) and in females from week 27 (P=0.0076). Fat mass and fat-free mass of all groups were significantly increased over time (all p<0.0001), with a large variation observed in fat mass. Baseline fat mass, fat-free mass and daily energy intake were significant predictors of future body weight for both sexes (p<0.0001). Baseline fat mass was a significant predictor of future body fat (p<0.0001). Conclusions Both males and females have large variations in fat mass, and this variability increases over time, while that of fat-free mass remains relatively stable. Sex differences exist in HFD responses and multivariate predicting models of body weight. PMID:24942674

Complex origins of silicate veinlets in HED meteorites: A case study of Northwest Africa 1109

NASA Astrophysics Data System (ADS)

Pang, Run-Lian; Zhang, Ai-Cheng; Wang, Ru-Cheng

2017-10-01

We report on the petrography and mineralogy of three types of silicate veinlets in the brecciated eucrite Northwest Africa (NWA) 1109. These include Fe-rich olivine, Mg-rich olivine, and pyroxene veinlets. The Fe-rich olivine veinlets mainly infill fractures in pyroxene and also occur along grain boundaries between pyroxene and plagioclase crystals, in both nonequilibrated and equilibrated lithic clasts. The host pyroxene of Fe-rich olivine veinlets shows large chemical variations between and within grains. The Fe-rich olivine veinlets also contain fine-grained Fe3+-bearing chromite, highly calcic plagioclase, merrillite, apatite, and troilite. Based on texture and mineral chemistry, we argue that the formation of Fe-rich olivine was related to fluid deposition at relatively high temperatures. However, the source of Fe-rich olivine in the veinlets remains unclear. Magnesium-rich olivine veinlets were found in three diogenitic lithic clasts. In one of these, the Mg-rich olivine veinlets only occur in one of the fine-grained interstitial regions and extend into fractures within surrounding coarse-grained orthopyroxene. Based on the texture of the interstitial materials, we suggest that the Mg-rich olivine veinlets formed by shock-induced localized melting and recrystallization. Pyroxene veinlets were only observed in one clast where they infill fractures within large plagioclase grains and are associated with fine-grained pyroxene surrounding coarse-grained pyroxene. The large chemical variations in pyroxene and the fracture-filling texture indicate that the pyroxene veinlets might also have formed by shock-induced localized melting and rapid crystallization. Our study demonstrates that silicate veinlets formed by a range of different surface processes on the surface of Vesta.

Spatial and seasonal heterogeneity of atmospheric particles induced reactive oxygen species in urban areas and the role of water-soluble metals.

PubMed

Gali, Nirmal Kumar; Yang, Fenhuan; Jiang, Sabrina Yanan; Chan, Ka Lok; Sun, Li; Ho, Kin-fai; Ning, Zhi

2015-03-01

Adverse health effects are associated with exposure to atmospheric particulate matter (PM), which carry various chemical constituents and induce both exogenous and endogenous oxidative stress. This study investigated the spatial and seasonal variability of PM-induced ROS at four sites with different characteristics in Hong Kong. Cytotoxicity, exogenous and endogenous ROS was determined on a dose and time dependent analysis. Large spatial variation of ROS was observed with fine PM at urban site showing highest ROS levels while coarse PM at traffic site ranks the top. No consistent seasonal difference was observed for ROS levels among all sites. The highly heterogeneous distribution of PM-induced ROS demonstrates the differential capability of PM to produce oxidative stress, and the need to use appropriate metrics as surrogates of exposure instead of PM mass in epidemiologic studies. Several transition metals were found associated with ROS by different degree illustrating the complexity of mechanisms involved. Copyright © 2015 Elsevier Ltd. All rights reserved.

Human-induced changes in the hydrology of the Western United States

USGS Publications Warehouse

Barnett, T.P.; Pierce, D.W.; Hidalgo, H.G.; Bonfils, Celine; Santer, B.D.; Das, T.; Bala, G.; Wood, A.W.; Nozawa, T.; Mirin, A.A.; Cayan, D.R.; Dettinger, M.D.

2008-01-01

Observations have shown that the hydrological cycle of the western United States changed significantly over the last half of the 20th century. We present a regional, multivariable climate change detection and attribution study, using a high-resolution hydrologic model forced by global climate models, focusing on the changes that have already affected this primarily arid region with a large and growing population. The results show that up to 60% of the climate-related trends of river flow, winter air temperature, and snow pack between 1950 and 1999 are human-induced. These results are robust to perturbation of study variates and methods. They portend, in conjunction with previous work, a coming crisis in water supply for the western United States.

Shock formation induced by poloidal flow and its effects on the edge stability in tokamaks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seol, J.; Aydemir, A. Y.; Shaing, K. C.

2016-04-15

In the high confinement mode of tokamaks, magnitude of the radial electric field increases at the edge. Thus, the poloidal flow inside the transport barrier can be sonic when the edge pressure gradient is not steep enough to make the poloidal flow subsonic. When the poloidal Mach number is close to unity, a shock appears in the low field side and causes a large density perturbation. In this study, we describe a shock induced by the sonic poloidal plasma flow. Then, an entropy production across the shock is calculated. Finally, we introduce a simple model for Type III edge localizedmore » modes using the poloidal density variation driven by the sonic poloidal flow.« less

Interspecific hybridization as a genomic stressor inducing mobilization of transposable elements in Drosophila

PubMed Central

Guerreiro, Maria Pilar García

2014-01-01

Transposable elements (TEs) are DNA sequences able to be mobilized in host genomes. They are currently recognized as the major mutation inducers because of their insertion in the target, their effect on neighboring regions, or their ectopic recombination. A large number of factors including chemical and physical factors as well as intraspecific crosses have traditionally been identified as inducers of transposition. Besides environmental factors, interspecific crosses have also been proposed as promoters of transposition of particular TEs in plants and different animals. Our previous published work includes a genome-wide survey with the set of genomic TEs and shows that interspecific hybridization between the species Drosophila buzzatii and Drosophila koepferae induces genomic instability by transposition bursts. A high percentage of this instability corresponds to TEs belonging to classes I and II. The detailed study of three TEs (Osvaldo, Helena, and Galileo), representative of the different TE families, shows an increase of transposition in hybrids compared with parental species, that varies depending on the element. This study suggests ample variation in TE regulation mechanisms and the question is why this variation occurs. Interspecific hybridization is a genomic stressor that disrupts the stability of TEs probably contributing to a relaxation of the mechanisms controlling TEs in the Drosophila genome. In this commentary paper we will discuss these results and the molecular mechanisms that could explain these increases of transposition rates observed in interspecific Drosophila hybrids. PMID:25136509

Variability Analysis of MOS Differential Amplifier

NASA Astrophysics Data System (ADS)

Aoki, Masakazu; Seto, Kenji; Yamawaki, Taizo; Tanaka, Satoshi

Variation characteristics in MOS differential amplifier are evaluated by using the concise statistical model parameters for SPICE simulation. We find that the variation in the differential-mode gain, Adm, induced by the current factor variation, Δβ0, in the Id-variation of the differential MOS transistors is more than one order of magnitude larger than that induced by the threshold voltage variation, ΔVth, which has been regarded as a major factor for circuit variations in SoC's (2). The results obtained by the Monte Carlo simulations are verified by the theoretical analysis combined with the sensitivity analysis which clarifies the specific device parameter dependences of the variation in Adm.

Investigating the Pressure-Induced Amorphization of Zeolitic Imidazolate Framework ZIF-8: Mechanical Instability Due to Shear Mode Softening.

PubMed

Ortiz, Aurélie U; Boutin, Anne; Fuchs, Alain H; Coudert, François-Xavier

2013-06-06

We provide the first molecular dynamics study of the mechanical instability that is the cause of pressure-induced amorphization of zeolitic imidazolate framework ZIF-8. By measuring the elastic constants of ZIF-8 up to the amorphization pressure, we show that the crystal-to-amorphous transition is triggered by the mechanical instability of ZIF-8 under compression, due to shear mode softening of the material. No similar softening was observed under temperature increase, explaining the absence of temperature-induced amorphization in ZIF-8. We also demonstrate the large impact of the presence of adsorbate in the pores on the mechanical stability and compressibility of the framework, increasing its shear stability. This first molecular dynamics study of ZIF mechanical properties under variations of pressure, temperature, and pore filling opens the way to a more comprehensive understanding of their mechanical stability, structural transitions, and amorphization.

Laser-induced tissue fluorescence in radiofrequency tissue-fusion characterization.

PubMed

Su, Lei; Fonseca, Martina B; Arya, Shobhit; Kudo, Hiromi; Goldin, Robert; Hanna, George B; Elson, Daniel S

2014-01-01

Heat-induced tissue fusion is an important procedure in modern surgery and can greatly reduce trauma, complications, and mortality during minimally invasive surgical blood vessel anastomosis, but it may also have further benefits if applied to other tissue types such as small and large intestine anastomoses. We present a tissue-fusion characterization technology using laser-induced fluorescence spectroscopy, which provides further insight into tissue constituent variations at the molecular level. In particular, an increase of fluorescence intensity in 450- to 550-nm range for 375- and 405-nm excitation suggests that the collagen cross-linking in fused tissues increased. Our experimental and statistical analyses showed that, by using fluorescence spectral data, good fusion could be differentiated from other cases with an accuracy of more than 95%. This suggests that the fluorescence spectroscopy could be potentially used as a feedback control method in online tissue-fusion monitoring.

Theoretical study of polarization insensitivity of carrier-induced refractive index change of multiple quantum well.

PubMed

Miao, Qingyuan; Zhou, Qunjie; Cui, Jun; He, Ping-An; Huang, Dexiu

2014-12-29

Characteristics of polarization insensitivity of carrier-induced refractive index change of 1.55 μm tensile-strained multiple quantum well (MQW) are theoretically investigated. A comprehensive MQW model is proposed to effectively extend the application range of previous models. The model considers the temperature variation as well as the nonuniform distribution of injected carrier in MQW. Tensile-strained MQW is expected to achieve polarization insensitivity of carrier-induced refractive index change over a wide wavelength range as temperature varies from 0°C to 40°C, while the magnitude of refractive index change keeps a large value (more than 3 × 10^-3). And that the polarization insensitivity of refractive index change can maintain for a wide range of carrier concentration. Multiple quantum well with different material and structure parameters is anticipated to have the similar polarization insensitivity of refractive index change, which shows the design flexibility.

Variational submanifolds of Euclidean spaces

NASA Astrophysics Data System (ADS)

Krupka, D.; Urban, Z.; Volná, J.

2018-03-01

Systems of ordinary differential equations (or dynamical forms in Lagrangian mechanics), induced by embeddings of smooth fibered manifolds over one-dimensional basis, are considered in the class of variational equations. For a given non-variational system, conditions assuring variationality (the Helmholtz conditions) of the induced system with respect to a submanifold of a Euclidean space are studied, and the problem of existence of these "variational submanifolds" is formulated in general and solved for second-order systems. The variational sequence theory on sheaves of differential forms is employed as a main tool for the analysis of local and global aspects (variationality and variational triviality). The theory is illustrated by examples of holonomic constraints (submanifolds of a configuration Euclidean space) which are variational submanifolds in geometry and mechanics.

Relative effect of temperature and pH on diel cycling of dissolved trace elements in prickly pear creek, Montana

USGS Publications Warehouse

Jones, Clain A.; Nimick, D.A.; McCleskey, R. Blaine

2004-01-01

Diel (24 hr) cycles in dissolved metal and As concentrations have been documented in many northern Rocky Mountain streams in the U.S.A. The cause(s) of the cycles are unknown, although temperature- and pH-dependent sorption reactions have been cited as likely causes. A light/dark experiment was conducted to isolate temperature and pH as variables affecting diel metal cycles in Prickly Pear Creek, Montana. Light and dark chambers containing sediment and a strand of macrophyte were placed in the stream to simulate instream temperature oscillations. Photosynthesis-induced pH changes were allowed to proceed in the light chambers while photosynthesis was prevented in the dark chambers. Water samples were collected periodically for 22 hr in late July 2001 from all chambers and the stream. In the stream, dissolved Zn concentrations increased by 300% from late afternoon to early morning, while dissolved As concentrations exhibited the opposite pattern, increasing 33% between early morning and late afternoon. Zn and As concentrations in the light chambers showed similar, though less pronounced, diel variations. Conversely, Zn and As concentrations in the dark chambers had no obvious diel variation, indicating that light, or light-induced reactions, caused the variation. Temperature oscillations were nearly identical between light and dark chambers, strongly suggesting that temperature was not controlling the diel variations. As expected, pH was negatively correlated (P < 0.01) with dissolved Zn concentrations and positively correlated with dissolved As concentrations in both the light and dark chambers. From these experiments, photosynthesis-induced pH changes were determined to be the major cause of the diel dissolved Zn and As cycles in Prickly Pear Creek. Further research is necessary in other streams to verify that this finding is consistent among streams having large differences in trace-element concentrations and mineralogy of channel substrate. ?? 2004 Kluwer Academic Publishers.

Ion size effects upon ionic exclusion from dielectric interfaces and slit nanopores

NASA Astrophysics Data System (ADS)

Buyukdagli, Sahin; Achim, C. V.; Ala-Nissila, T.

2011-05-01

A previously developed field-theoretic model (Coalson et al 1995 J. Chem. Phys. 102 4584) that treats core collisions and Coulomb interactions on the same footing is investigated in order to understand ion size effects on the partition of neutral and charged particles at planar interfaces and the ionic selectivity of slit nanopores. We introduce a variational scheme that can go beyond the mean-field (MF) regime and couple in a consistent way pore-modified core interactions, steric effects, electrostatic solvation and image-charge forces, and surface charge induced electrostatic potential. Density profiles of neutral particles in contact with a neutral hard wall, obtained from Monte Carlo (MC) simulations are compared with the solutions of mean-field and variational equations. A recently proposed random-phase approximation (RPA) method is tested as well. We show that in the dilute limit, the MF and the variational theories agree well with simulation results, in contrast to the RPA method. The partition of charged Yukawa particles at a neutral dielectric interface (e.g. an air-water or protein-water interface) is investigated. It is shown that as a result of the competition between core collisions that push the ions toward the surface, and repulsive solvation and image forces that exclude them from the interface, a concentration peak of finite size ions sets in close to the dielectric interface. This effect is amplified with increasing ion size and bulk concentration. An integral expression for the surface tension that accounts for excluded volume effects is computed and the decrease of the surface tension with increasing ion size is illustrated. We also characterize the role played by the ion size in the ionic selectivity of neutral slit nanopores. We show that the complex interplay between electrostatic forces, excluded volume effects induced by core collisions and steric effects leads to an unexpected reversal in the ionic selectivity of the pore with varying pore size: while large pores exhibit a higher conductivity for large ions, narrow pores exclude large ions more efficiently than small ones.

[Study of microorganism sterilization by instant microwave and electromagnetic pulse].

PubMed

Lu, Zhiyuan; Shi, Pinpin; Zhu, Manzuo; Sun, Wenquan; Ding, Hua; Hou, Jianqiang

2008-08-01

The sterilization effects of constant electromagnetic wave and instant pulse on foods and traditional Chinese medical pills are introduced in this paper. From the velum's voltage variation caused by the outward electric filed,the dielectric properties of membranaceous ion and the pass rate of the membranaceous ion, we could analyze the biological heating effect and the biological non-heating effect. The sterilization effect of constant electromagnetic wave is based on the biological heating effect, while the instant electromagnetic pulse is based on the biological non-heating effect. With the applied electronic field, the voltage of membrane could increase, which results in the gates of K+ open, and the flowing out of K+. And the variation of the membranaceous voltage makes the gates of Ca2+ open. The Ca2+ of large consistency could come into the cell by the gradient of voltage. It could induce the death of the cells. The greater the variation of membranaceous voltage becomes, the higher will be the death rate of the cells.

Robust dynamic myocardial perfusion CT deconvolution using adaptive-weighted tensor total variation regularization

NASA Astrophysics Data System (ADS)

Gong, Changfei; Zeng, Dong; Bian, Zhaoying; Huang, Jing; Zhang, Xinyu; Zhang, Hua; Lu, Lijun; Feng, Qianjin; Liang, Zhengrong; Ma, Jianhua

2016-03-01

Dynamic myocardial perfusion computed tomography (MPCT) is a promising technique for diagnosis and risk stratification of coronary artery disease by assessing the myocardial perfusion hemodynamic maps (MPHM). Meanwhile, the repeated scanning of the same region results in a relatively large radiation dose to patients potentially. In this work, we present a robust MPCT deconvolution algorithm with adaptive-weighted tensor total variation regularization to estimate residue function accurately under the low-dose context, which is termed `MPD-AwTTV'. More specifically, the AwTTV regularization takes into account the anisotropic edge property of the MPCT images compared with the conventional total variation (TV) regularization, which can mitigate the drawbacks of TV regularization. Subsequently, an effective iterative algorithm was adopted to minimize the associative objective function. Experimental results on a modified XCAT phantom demonstrated that the present MPD-AwTTV algorithm outperforms and is superior to other existing deconvolution algorithms in terms of noise-induced artifacts suppression, edge details preservation and accurate MPHM estimation.

Effects of Extreme Obliquity Variations on the Habitability of Exoplanets

NASA Technical Reports Server (NTRS)

Armstrong, J. C.; Barnes, R.; Domagal-Goldman, S.; Breiner, J.; Quinn, T. R.; Meadows, V. S.

2014-01-01

We explore the impact of obliquity variations on planetary habitability in hypothetical systems with high mutual inclination. We show that large-amplitude, high-frequency obliquity oscillations on Earth-like exoplanets can suppress the ice-albedo feedback, increasing the outer edge of the habitable zone. We restricted our exploration to hypothetical systems consisting of a solar-mass star, an Earth-mass planet at 1 AU, and 1 or 2 larger planets. We verified that these systems are stable for 108 years with N-body simulations and calculated the obliquity variations induced by the orbital evolution of the Earth-mass planet and a torque from the host star. We ran a simplified energy balance model on the terrestrial planet to assess surface temperature and ice coverage on the planet's surface, and we calculated differences in the outer edge of the habitable zone for planets with rapid obliquity variations. For each hypothetical system, we calculated the outer edge of habitability for two conditions: (1) the full evolution of the planetary spin and orbit and (2) the eccentricity and obliquity fixed at their average values. We recovered previous results that higher values of fixed obliquity and eccentricity expand the habitable zone, but we also found that obliquity oscillations further expand habitable orbits in all cases. Terrestrial planets near the outer edge of the habitable zone may be more likely to support life in systems that induce rapid obliquity oscillations as opposed to fixed-spin planets. Such planets may be the easiest to directly characterize with space-borne telescopes.

Effects of extreme obliquity variations on the habitability of exoplanets.

PubMed

Armstrong, J C; Barnes, R; Domagal-Goldman, S; Breiner, J; Quinn, T R; Meadows, V S

2014-04-01

We explore the impact of obliquity variations on planetary habitability in hypothetical systems with high mutual inclination. We show that large-amplitude, high-frequency obliquity oscillations on Earth-like exoplanets can suppress the ice-albedo feedback, increasing the outer edge of the habitable zone. We restricted our exploration to hypothetical systems consisting of a solar-mass star, an Earth-mass planet at 1 AU, and 1 or 2 larger planets. We verified that these systems are stable for 10(8) years with N-body simulations and calculated the obliquity variations induced by the orbital evolution of the Earth-mass planet and a torque from the host star. We ran a simplified energy balance model on the terrestrial planet to assess surface temperature and ice coverage on the planet's surface, and we calculated differences in the outer edge of the habitable zone for planets with rapid obliquity variations. For each hypothetical system, we calculated the outer edge of habitability for two conditions: (1) the full evolution of the planetary spin and orbit and (2) the eccentricity and obliquity fixed at their average values. We recovered previous results that higher values of fixed obliquity and eccentricity expand the habitable zone, but we also found that obliquity oscillations further expand habitable orbits in all cases. Terrestrial planets near the outer edge of the habitable zone may be more likely to support life in systems that induce rapid obliquity oscillations as opposed to fixed-spin planets. Such planets may be the easiest to directly characterize with space-borne telescopes.

Hydraulic tests in highly permeable aquifers

NASA Astrophysics Data System (ADS)

Butler, James J.; Zhan, Xiaoyong

2004-12-01

A semianalytical solution is presented for a mathematical model describing the flow of groundwater in response to a slug or pumping test in a highly permeable, confined aquifer. This solution, which is appropriate for wells of any degree of penetration and incorporates inertial mechanisms at both the test and observation wells, can be used to gain new insights into hydraulic tests in highly permeable settings. The oscillatory character of slug- and pumping-induced responses will vary considerably across a site, even in an essentially homogeneous formation, when wells of different radii, depths, and screen lengths are used. Thus variations in the oscillatory character of responses do not necessarily indicate variations in hydraulic conductivity (K). Existing models for slug tests in partially penetrating wells in high-K aquifers neglect the storage properties of the media. That assumption, however, appears reasonable for a wide range of common conditions. Unlike in less permeable formations, drawdown at an observation well in a high-K aquifer will be affected by head losses in the pumping well. Those losses, which affect the form of the pumping-induced oscillations, can be difficult to characterize. Thus analyses of observation-well drawdown should utilize data from the period after the oscillations have dissipated whenever possible. Although inertial mechanisms can have a large impact on early-time drawdown, that impact decreases rapidly with duration of pumping and distance to the observation well. Conventional methods that do not consider inertial mechanisms should therefore be viable options for the analysis of drawdown data at moderate to large times.

Wave-driven spatial and temporal variability in sea-floor sediment mobility in the Monterey Bay, Cordell Bank, and Gulf of the Farallones National Marine Sanctuaries

USGS Publications Warehouse

Storlazzi, Curt D.; Reid, Jane A.; Golden, Nadine E.

2007-01-01

Wind and wave patterns affect many aspects of continental shelves and shorelines geomorphic evolution. Although our understanding of the processes controlling sediment suspension on continental shelves has improved over the past decade, our ability to predict sediment mobility over large spatial and temporal scales remains limited. The deployment of robust operational buoys along the U.S. West Coast in the early 1980s provides large quantities of high-resolution oceanographic and meteorologic data. By 2006, these data sets were long enough to clearly identify long-term trends and compute statistically significant probability estimates of wave and wind behavior during annual and interannual climatic cycles (that is, El Niño and La Niña). Wave-induced sediment mobility on the shelf and upper slope off central California was modeled using synthesized oceanographic and meteorologic data as boundary input for the Delft SWAN model, sea-floor grain-size data provided by the usSEABED database, and regional bathymetry. Differences in waves (heights, periods, and directions) and winds (speeds and directions) between El Niño and La Niña months cause temporal and spatial variations in peak wave-induced bed shear stresses. These variations, in conjunction with spatially heterogeneous unconsolidated sea-floor sedimentary cover, result in predicted sediment mobility widely varying in both time and space. These findings indicate that these factors have significant consequences for both geological and biological processes.

Hydraulic tests in highly permeable aquifers

USGS Publications Warehouse

Butler, James J.; Zhan, Xiaoyong

2004-01-01

A semianalytical solution is presented for a mathematical model describing the flow of groundwater in response to a slug or pumping test in a highly permeable, confined aquifer. This solution, which is appropriate for wells of any degree of penetration and incorporates inertial mechanisms at both the test and observation wells, can be used to gain new insights into hydraulic tests in highly permeable settings. The oscillatory character of slug‐ and pumping‐induced responses will vary considerably across a site, even in an essentially homogeneous formation, when wells of different radii, depths, and screen lengths are used. Thus variations in the oscillatory character of responses do not necessarily indicate variations in hydraulic conductivity (K). Existing models for slug tests in partially penetrating wells in high‐K aquifers neglect the storage properties of the media. That assumption, however, appears reasonable for a wide range of common conditions. Unlike in less permeable formations, drawdown at an observation well in a high‐K aquifer will be affected by head losses in the pumping well. Those losses, which affect the form of the pumping‐induced oscillations, can be difficult to characterize. Thus analyses of observation‐well drawdown should utilize data from the period after the oscillations have dissipated whenever possible. Although inertial mechanisms can have a large impact on early‐time drawdown, that impact decreases rapidly with duration of pumping and distance to the observation well. Conventional methods that do not consider inertial mechanisms should therefore be viable options for the analysis of drawdown data at moderate to large times.

Respiration Induced Heart Motion and Indications of Gated Delivery for Left-Sided Breast Irradiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qi, X. Sharon, E-mail: xiangrong.qi@ucdenver.edu; Hu, Angela; Wang Kai

Purpose: To investigate respiration-induced heart motion for left-sided breast irradiation using a four-dimensional computed tomography (4DCT) technique and to determine novel indications to assess heart motion and identify breast patients who may benefit from a gated treatment. Methods and Materials: Images of 4DCT acquired during free breathing for 20 left-sided breast cancer patients, who underwent whole breast irradiation with or without regional nodal irradiation, were analyzed retrospectively. Dose distributions were reconstructed in the phases of 0%, 20%, and 50%. The intrafractional heart displacement was measured in three selected transverse CT slices using D{sub LAD} (the distance from left ascending aortamore » to a fixed line [connecting middle point of sternum and the body] drawn on each slice) and maximum heart depth (MHD, the distance of the forefront of the heart to the line). Linear regression analysis was used to correlate these indices with mean heart dose and heart dose volume at different breathing phases. Results: Respiration-induced heart displacement resulted in observable variations in dose delivered to the heart. During a normal free-breathing cycle, heart-induced motion D{sub LAD} and MHD changed up to 9 and 11 mm respectively, resulting in up to 38% and 39% increases of mean doses and V{sub 25.2} for the heart. MHD and D{sub LAD} were positively correlated with mean heart dose and heart dose volume. Respiratory-adapted gated treatment may better spare heart and ipsilateral-lung compared with the conventional non-gated plan in a subset of patients with large D{sub LAD} or MHD variations. Conclusion: Proposed indices offer novel assessment of heart displacement based on 4DCT images. MHD and D{sub LAD} can be used independently or jointly as selection criteria for respiratory gating procedure before treatment planning. Patients with great intrafractional MHD variations or tumor(s) close to the diaphragm may particularly benefit from the gated treatment.« less

Expression of B-class MADS-box genes in response to variations in photoperiod is associated with chasmogamous and cleistogamous flower development in Viola philippica.

PubMed

Li, Qiaoxia; Huo, Qingdi; Wang, Juan; Zhao, Jing; Sun, Kun; He, Chaoying

2016-07-07

Some plants develop a breeding system that produces both chasmogamous (CH) and cleistogamous (CL) flowers. However, the underlying molecular mechanism remains elusive. In the present study, we observed that Viola philippica develops CH flowers with short daylight, whereas an extended photoperiod induces the formation of intermediate CL and CL flowers. In response to long daylight, the respective number and size of petals and stamens was lower and smaller than those of normally developed CH flowers, and a minimum of 14-h light induced complete CL flowers that had no petals but developed two stamens of reduced fertility. The floral ABC model indicates that B-class MADS-box genes largely influence the development of the affected two-whorl floral organs; therefore, we focused on characterizing these genes in V. philippica to understand this particular developmental transition. Three such genes were isolated and respectively designated as VpTM6-1, VpTM6-2, and VpPI. These were differentially expressed during floral development (particularly in petals and stamens) and the highest level of expression was observed in CH flowers; significantly low levels were detected in intermediate CL flowers, and the lowest level in CL flowers. The observed variations in the levels of expression after floral induction and organogenesis apparently occurred in response to variations in photoperiod. Therefore, inhibition of the development of petals and stamens might be due to the downregulation of B-class MADS-box gene expression by long daylight, thereby inducing the generation of CL flowers. Our work contributes to the understanding of the adaptive evolutionary formation of dimorphic flowers in plants.

Modelling Wind Effects on Subtidal Salinity in Apalachicola Bay, Florida

NASA Astrophysics Data System (ADS)

Huang, W.; Jones, W. K.; Wu, T. S.

2002-07-01

Salinity is an important factor for oyster and estuarine productivity in Apalachicola Bay. Observations of salinity at oyster reefs have indicated a high correlation between subtidal salinity variations and the surface winds along the bay axis in an approximately east-west direction. In this paper, we applied a calibrated hydrodynamic model to examine the surface wind effects on the volume fluxes in the tidal inlets and the subtidal salinity variations in the bay. Model simulations show that, due to the large size of inlets located at the east and west ends of this long estuary, surface winds have significant effects on the volume fluxes in the estuary inlets for the water exchanges between the estuary and ocean. In general, eastward winds cause the inflow from the inlets at the western end and the outflow from inlets at the eastern end of the bay. Winds at 15 mph speed in the east-west direction can induce a 2000 m3 s-1 inflow of saline seawater into the bay from the inlets, a rate which is about 2·6 times that of the annual average freshwater inflow from the river. Due to the varied wind-induced volume fluxes in the inlets and the circulation in the bay, the time series of subtidal salinity at oyster reefs considerably increases during strong east-west wind conditions in comparison to salinity during windless conditions. In order to have a better understanding of the characteristics of the wind-induced subtidal circulation and salinity variations, the researchers also connected model simulations under constant east-west wind conditions. Results show that the volume fluxes are linearly proportional to the east-west wind stresses. Spatial distributions of daily average salinity and currents clearly show the significant effects of winds on the bay.

Vegetation controls on the biophysical surface properties at global scale

NASA Astrophysics Data System (ADS)

Forzieri, Giovanni; Cescatti, Alessandro

2016-04-01

Leaf area index (LAI) plays an important role in determining resistances to heat, moisture and momentum exchanges between the land surface and atmosphere. Exploring how variations in LAI may induce changes in the surface energy balance is a key to understanding vegetation-climate interactions and for predicting biophysical climate impacts associated to changes in land cover. To this end, we analyzed remote sensing-observed dynamics in LAI, surface energy fluxes and climate drivers at global scale. We investigated the link between interannual variability of LAI and the components of the surface energy budget under diverse climate gradients. Results show that a 25% increase in annual LAI may induce up to 2% increase in available surface energy, as consequence of higher short wave absorption due to reduced albedos, up to 20% increase and 10% decrease in latent and sensible heat, respectively, leading to a decrease of the Bowen ratio in densely vegetated canopies. Opposite patterns are found for a reduction in LAI of similar magnitude. Such changes are strongly modulated by concurrent year-to-year variations and climatological means of air temperature, precipitation and snow cover as well as by land cover-specific physiological processes. Boreal and semi-arid regions appear to be mostly exposed to large changes in biophysical surface processes induced by interannual fluctuations in LAI. The combination of the emergent patters translates into variations in the long-wave outgoing radiation that reflect the surface warming/cooling associated to LAI changes. These findings provide a deeper understanding of the vegetation control on biophysical surface properties and define a set of observational-based diagnostics of LAI-dependent land surface-atmosphere interactions.

Genetic and Epigenetic Variations Induced by Wheat-Rye 2R and 5R Monosomic Addition Lines

PubMed Central

Fu, Shulan; Sun, Chuanfei; Yang, Manyu; Fei, Yunyan; Tan, Feiqun; Yan, Benju; Ren, Zhenglong; Tang, Zongxiang

2013-01-01

Background Monosomic alien addition lines (MAALs) can easily induce structural variation of chromosomes and have been used in crop breeding; however, it is unclear whether MAALs will induce drastic genetic and epigenetic alterations. Methodology/Principal Findings In the present study, wheat-rye 2R and 5R MAALs together with their selfed progeny and parental common wheat were investigated through amplified fragment length polymorphism (AFLP) and methylation-sensitive amplification polymorphism (MSAP) analyses. The MAALs in different generations displayed different genetic variations. Some progeny that only contained 42 wheat chromosomes showed great genetic/epigenetic alterations. Cryptic rye chromatin has introgressed into the wheat genome. However, one of the progeny that contained cryptic rye chromatin did not display outstanding genetic/epigenetic variation. 78 and 49 sequences were cloned from changed AFLP and MSAP bands, respectively. Blastn search indicated that almost half of them showed no significant similarity to known sequences. Retrotransposons were mainly involved in genetic and epigenetic variations. Genetic variations basically affected Gypsy-like retrotransposons, whereas epigenetic alterations affected Copia-like and Gypsy-like retrotransposons equally. Genetic and epigenetic variations seldom affected low-copy coding DNA sequences. Conclusions/Significance The results in the present study provided direct evidence to illustrate that monosomic wheat-rye addition lines could induce different and drastic genetic/epigenetic variations and these variations might not be caused by introgression of rye chromatins into wheat. Therefore, MAALs may be directly used as an effective means to broaden the genetic diversity of common wheat. PMID:23342073

Genetic and epigenetic variations induced by wheat-rye 2R and 5R monosomic addition lines.

PubMed

Fu, Shulan; Sun, Chuanfei; Yang, Manyu; Fei, Yunyan; Tan, Feiqun; Yan, Benju; Ren, Zhenglong; Tang, Zongxiang

2013-01-01

Monosomic alien addition lines (MAALs) can easily induce structural variation of chromosomes and have been used in crop breeding; however, it is unclear whether MAALs will induce drastic genetic and epigenetic alterations. In the present study, wheat-rye 2R and 5R MAALs together with their selfed progeny and parental common wheat were investigated through amplified fragment length polymorphism (AFLP) and methylation-sensitive amplification polymorphism (MSAP) analyses. The MAALs in different generations displayed different genetic variations. Some progeny that only contained 42 wheat chromosomes showed great genetic/epigenetic alterations. Cryptic rye chromatin has introgressed into the wheat genome. However, one of the progeny that contained cryptic rye chromatin did not display outstanding genetic/epigenetic variation. 78 and 49 sequences were cloned from changed AFLP and MSAP bands, respectively. Blastn search indicated that almost half of them showed no significant similarity to known sequences. Retrotransposons were mainly involved in genetic and epigenetic variations. Genetic variations basically affected Gypsy-like retrotransposons, whereas epigenetic alterations affected Copia-like and Gypsy-like retrotransposons equally. Genetic and epigenetic variations seldom affected low-copy coding DNA sequences. The results in the present study provided direct evidence to illustrate that monosomic wheat-rye addition lines could induce different and drastic genetic/epigenetic variations and these variations might not be caused by introgression of rye chromatins into wheat. Therefore, MAALs may be directly used as an effective means to broaden the genetic diversity of common wheat.

Estimated preejection period (PEP) based on the detection of the R-wave and dZ/dt-min peaks in ECG and ICG

NASA Astrophysics Data System (ADS)

van Lien, René; Schutte, Nienke M.; Meijer, Jan H.; de Geus, Eco J. C.

2013-04-01

The validity of estimating the PEP from a fixed value for the Q-wave onset to the R-wave peak (QR) interval and from the R-wave peak to the dZ/dt-min peak (ISTI) interval is evaluated. Ninety-one subjects participated in a laboratory experiment in which a variety of physical and mental stressors were presented and 31 further subjects participated in a sequence of structured ambulatory activities in which large variation in posture and physical activity was induced. PEP, QR interval, and ISTI were scored. Across the diverse laboratory and ambulatory conditions the QR interval could be approximated by a fixed interval of 40 ms but 95% confidence intervals were large (25 to 54 ms). Multilevel analysis showed that 79% to 81% of the within and between-subject variation in the RB interval could be predicted by the ISTI. However, the optimal intercept and slope values varied significantly across subjects and study setting. Bland-Altman plots revealed a large discrepancy between the estimated PEP and the actual PEP based on the Q-wave onset and B-point. It is concluded that the estimated PEP can be a useful tool but cannot replace the actual PEP to index cardiac sympathetic control.

Sedimentary records of trace elements from large European lakes (Switzerland) document historic to recent freshwater pollution and climate-induced runoff variations

NASA Astrophysics Data System (ADS)

Thevenon, F.; Wirth, S. B.; Fujak, M.; Poté, J.; Thierry, A.; Chiaradia, M.; Girardclos, S.

2011-12-01

Continuous sedimentary records of anthropogenic and natural trace elements determined by ICPMS, from 5 large and deep perialpine lakes from Central Europe (Switzerland), evidence the environmental impacts of industrial fossil fuel pollution. In fact, the greatest increase in heavy metal pollution was registered at all the studied sites following the European industrial revolution of ca. AD 1800; with the highest values during the middle part of the 20th century. On a regional scale, anthropogenic heavy metal input subsequently stopped increasing thanks to remediation strategies such as the implementation of wastewater treatment plants (WWTPs). On the other hand, the discharge of industrial treated wastewaters into Vidy Bay of Lake Geneva during the second part of the 20th century involved the sedimentation of highly contaminated sediments in the area surrounding the WWTP outlet pipe discharge; less than 4 km from the main supply of drinking water of Lausanne (127'000 hab.). Microbial analyses furthermore reveal i) high increase in bacterial densities following the lake eutrophication in the 1970s, and that ii) the related sediments can be considered as a reservoir of antibiotic resistant bacteria/genes (of human origin). We finally compare instrumental hydrological data over the last century with variations of lithogenic trace elements (e.g., titanium) as registered in three large lakes (Brienz, Thun and Bienne) connected by the River Aar. This task allows to better constraining the runoff variations on a regional scale over the last decades for the the River Aar, and its possible increase under warming climate conditions in the European Alps.

SOAP 2.0: A Tool to Estimate the Photometric and Radial Velocity Variations Induced by Stellar Spots and Plages

NASA Astrophysics Data System (ADS)

Dumusque, X.; Boisse, I.; Santos, N. C.

2014-12-01

This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the case of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i <=8 km s-1. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation. . The work in this paper is based on observations made with the MOST satellite, the HARPS instrument on the ESO 3.6 m telescope at La Silla Observatory (Chile), and the SOPHIE instrument at the Observatoire de Haute Provence (France).

Does clutch size evolve in response to parasites and immunocompetence?

USGS Publications Warehouse

Martin, T.E.; Moller, A.P.; Merino, S.; Clobert, J.

2001-01-01

Parasites have been argued to influence clutch size evolution, but past work and theory has largely focused on within-species optimization solutions rather than clearly addressing among-species variation. The effects of parasites on clutch size variation among species can be complex, however, because different parasites can induce age-specific differences in mortality that can cause clutch size to evolve in different directions. We provide a conceptual argument that differences in immunocompetence among species should integrate differences in overall levels of parasite-induced mortality to which a species is exposed. We test this assumption and show that mortality caused by parasites is positively correlated with immunocompetence measured by cell-mediated measures. Under life history theory, clutch size should increase with increased adult mortality and decrease with increased juvenile mortality. Using immunocompetence as a general assay of parasite-induced mortality, we tested these predictions by using data for 25 species. We found that clutch size increased strongly with adult immunocompetence. In contrast, clutch size decreased weakly with increased juvenile immunocompetence. But, immunocompetence of juveniles may be constrained by selection on adults, and, when we controlled for adult immunocompetence, clutch size decreased with juvenile immunocompetence. Thus, immunocompetence seems to reflect evolutionary differences in parasite virulence experienced by species, and differences in age-specific parasite virulence appears to exert opposite selection on clutch size evolution.

River-induced flow dynamics in long-screen wells and impact on aqueous samples.

PubMed

Vermeul, Vince R; McKinley, James P; Newcomer, Darrell R; Mackley, Robert D; Zachara, J M

2011-01-01

Previously published field investigations and modeling studies have demonstrated the potential for sample bias associated with vertical wellbore flow in conventional monitoring wells constructed with long-screened intervals. This article builds on the existing body of literature by (1) demonstrating the utility of continuous (i.e., hourly measurements for ∼1 month) ambient wellbore flow monitoring and (2) presenting results from a field experiment where relatively large wellbore flows (up to 4 L/min) were induced by aquifer hydrodynamics associated with a fluctuating river boundary located approximately 250 m from the test well. The observed vertical wellbore flows were strongly correlated with fluctuations in river stage, alternating between upward and downward flow throughout the monitoring period in response to changes in river stage. Continuous monitoring of ambient wellbore flows using an electromagnetic borehole flowmeter allowed these effects to be evaluated in concert with continuously monitored river-stage elevations (hourly) and aqueous uranium concentrations (daily) in a long-screen well and an adjacent multilevel well cluster. This study demonstrates that when contaminant concentrations within the aquifer vary significantly over the depth interval interrogated, river-induced vertical wellbore flow can result in variations in measured concentration that nearly encompass the full range of variation in aquifer contaminant concentration with depth. Copyright © 2010 Battelle Memorial Institute. Journal compilation © 2010 National Ground Water Association.

[Correlation of intraocular pressure variation after visual field examination with 24-hour intraocular pressure variations in primary open-angle glaucoma].

PubMed

Noro, Takahiko; Nakamoto, Kenji; Sato, Makoto; Yasuda, Noriko; Ito, Yoshinori; Ogawa, Shumpei; Nakano, Tadashi; Tsuneoka, Hiroshi

2014-10-01

We retrospectively examined intraocular pressure variations after visual field examination in primary open angle glaucoma (POAG), together with its influencing factors and its association with 24-hour intraocular pressure variations. Subjects were 94 eyes (52 POAG patients) subjected to measurements of 24-hour intraocular pressure and of changes in intraocular pressure after visual field examination using a Humphrey Visual Field Analyzer. Subjects were classified into three groups according to the magnitude of variation (large, intermediate and small), and 24-hour intraocular pressure variations were compared among the three groups. Factors influencing intraocular pressure variations after visual field examination and those associated with the large variation group were investigated. Average intraocular pressure variation after visual field examination was -0.28 ± 1.90 (range - 6.0(-) + 5.0) mmHg. No significant influencing factors were identified. The intraocular pressure at 3 a.m. was significantly higher in the large variation group than other two groups (p < 0.001). Central corneal thickness was correlated with the large variation group (odds ratio = 1.04; 95% confidence interval, 1.01-1.07 ; p = 0.02). No particular tendencies in intraocular pressure variations were found after visual field examination. Increases in intraocular pressure during the night might be associated with large intraocular pressure variations after visual field examination.

Global seasonal strain and stress models derived from GRACE loading, and their impact on seismicity

NASA Astrophysics Data System (ADS)

Chanard, K.; Fleitout, L.; Calais, E.; Craig, T. J.; Rebischung, P.; Avouac, J. P.

2017-12-01

Loading by continental water, atmosphere and oceans deforms the Earth at various spatio-temporal scales, inducing crustal and mantelic stress perturbations that may play a role in earthquake triggering.Deformation of the Earth by this surface loading is observed in GNSS position time series. While various models predict well vertical observations, explaining horizontal displacements remains challenging. We model the elastic deformation induced by loading derived from GRACE for coefficients 2 and higher. We estimate the degree-1 deformation field by comparison between predictions of our model and IGS-repro2 solutions at a globally distributed network of 700 GNSS sites, separating the horizontal and vertical components to avoid biases between components. The misfit between model and data is reduced compared to previous studies, particularly on the horizontal component. The associated geocenter motion time series are consistent with results derived from other datasets. We also discuss the impact on our results of systematic errors in GNSS geodetic products, in particular of the draconitic error.We then compute stress tensors time series induced by GRACE loads and discuss the potential link between large scale seasonal mass redistributions and seismicity. Within the crust, we estimate hydrologically induced stresses in the intraplate New Madrid Seismic Zone, where secular stressing rates are unmeasurably low. We show that a significant variation in the rate of micro-earthquakes at annual and multi-annual timescales coincides with stresses induced by hydrological loading in the upper Mississippi embayment, with no significant phase-lag, directly modulating regional seismicity. We also investigate pressure variations in the mantle transition zone and discuss potential correlations between the statistically significant observed seasonality of deep-focus earthquakes, most likely due to mineralogical transformations, and surface hydrological loading.

Solar-induced 27-day variations of polar mesospheric clouds from the AIM SOFIE and CIPS experiments

NASA Astrophysics Data System (ADS)

Thurairajah, Brentha; Thomas, Gary E.; von Savigny, Christian; Snow, Martin; Hervig, Mark E.; Bailey, Scott M.; Randall, Cora E.

2017-09-01

Polar Mesospheric Cloud (PMC) observations from the Solar Occultation for Ice Experiment (SOFIE) and the Cloud Imaging and Particle Size (CIPS) experiment are used to investigate the response of PMCs to forcing associated with the 27-day solar rotation. We quantify the PMC response in terms of sensitivity values. Analysis of PMC data from 14 seasons indicate a large seasonal variability in sensitivity with both correlation and anti-correlation between PMC properties and Lyman-alpha irradiance for individual seasons. However, a superposed epoch analysis reveals the expected anti-correlation between variations in solar Lyman-alpha and variations in PMC ice water content, albedo, and frequency of occurrence. The PMC height is found to significantly correlate with 27-day variations in solar Lyman-alpha in the Southern Hemisphere (SH), but not in the Northern hemisphere (NH). Depending on instrument and property, the time lag between variations in PMC properties and solar Lyman-alpha ranges from 0 to 3 days in the NH and from 6 to 7 days in the SH. These hemispheric differences in PMC height and time lag are not understood, but it is speculated that they result from dynamical forcing that is controlled by the 27-day solar cycle.

Patterns of tree growth in relation to environmental variability in the tropical dry deciduous forest at Mudumalai, southern India.

PubMed

Nath, Cheryl D; Dattaraja, H S; Suresh, H S; Joshi, N V; Sukumar, R

2006-12-01

Tree diameter growth is sensitive to environmental fluctuations and tropical dry forests experience high seasonal and inter-annual environmental variation. Tree growth rates in a large permanent plot at Mudumalai, southern India, were examined for the influences of rainfall and three intrinsic factors (size, species and growth form) during three 4-year intervals over the period 1988-2000. Most trees had lowest growth during the second interval when rainfall was lowest, and skewness and kurtosis of growth distributions were reduced during this interval. Tree diameter generally explained less than 10% of growth variation and had less influence on growth than species identity or time interval. Intraspecific variation was high, yet species identity accounted for up to 16% of growth variation in the community. There were no consistent differences between canopy and understory tree growth rates; however, a few subgroups of species may potentially represent canopy and understory growth guilds. Environmentally-induced temporal variations in growth generally did not reduce the odds of subsequent survival. Growth rates appear to be strongly influenced by species identity and environmental variability in the Mudumalai dry forest. Understanding and predicting vegetation dynamics in the dry tropics thus also requires information on temporal variability in local climate.

Molecular Dynamics Simulations of the Temperature Induced Unfolding of Crambin Follow the Arrhenius Equation.

PubMed

Dalby, Andrew; Shamsir, Mohd Shahir

2015-01-01

Molecular dynamics simulations have been used extensively to model the folding and unfolding of proteins. The rates of folding and unfolding should follow the Arrhenius equation over a limited range of temperatures. This study shows that molecular dynamic simulations of the unfolding of crambin between 500K and 560K do follow the Arrhenius equation. They also show that while there is a large amount of variation between the simulations the average values for the rate show a very high degree of correlation.

Molecular Dynamics Simulations of the Temperature Induced Unfolding of Crambin Follow the Arrhenius Equation.

PubMed Central

Dalby, Andrew; Shamsir, Mohd Shahir

2015-01-01

Molecular dynamics simulations have been used extensively to model the folding and unfolding of proteins. The rates of folding and unfolding should follow the Arrhenius equation over a limited range of temperatures. This study shows that molecular dynamic simulations of the unfolding of crambin between 500K and 560K do follow the Arrhenius equation. They also show that while there is a large amount of variation between the simulations the average values for the rate show a very high degree of correlation. PMID:26539292

Entry flight control system downmoding evaluation

NASA Technical Reports Server (NTRS)

Barnes, H. A.

1978-01-01

A method to desensitize the entry flight control system to structural vibration feedback which might induce an oscillatory instability is described. Trends in vehicle response and handling characteristics as a function of gain combinations in the FCS forward and rate feedback loops were described as observed in a man-in-the-loop simulation. Among the flight conditions considered are the effects of downmoding with APU failures, off-nominal trajectory conditions, sensed angle of attack errors, the impact on RCS fuel consumption, performance in the presence of aero variations, recovery from large FCS upsets, and default gains.

Infrasound induced instability by modulation of condensation process in the atmosphere.

PubMed

Naugolnykh, Konstantin; Rybak, Samuil

2008-12-01

A sound wave in supersaturated water vapor can modulate both the process of heat release caused by condensation, and subsequently, as a result, the resonance interaction of sound with the modulated heat release provides sound amplification. High-intensity atmospheric perturbations such as cyclones and thunderstorms generate infrasound, which is detectable at large distances from the source. The wave-condensation instability can lead to variation in the level of infrasound radiation by a developing cyclone, and this can be as a precursor of these intense atmospheric events.

Interannual Variation of Surface Circulation in the Japan/East Sea due to External Forcings and Intrinsic Variability

NASA Astrophysics Data System (ADS)

Choi, Byoung-Ju; Cho, Seong Hun; Jung, Hee Seok; Lee, Sang-Ho; Byun, Do-Seong; Kwon, Kyungman

2018-03-01

The interannual variation of surface ocean currents can be as large as seasonal variation in the Japan/East Sea (JES). To identify the major factors that cause such interannual variability of surface ocean circulation in the JES, surface circulation was simulated from 1998 to 2009 using a three-dimensional model. Contributions of atmospheric forcing (ATM), open boundary data (OBC), and intrinsic variability (ITV) of the surface flow in the JES on the interannual variability of surface ocean circulation were separately examined using numerical simulations. Variability in surface circulation was quantified in terms of variance in sea surface height, 100-m depth water temperature, and surface currents. ITV was found to be the dominant factor that induced interannual variabilities of surface circulation, the main path of the East Korea Warm Current (EKWC), and surface kinetic energy on a time scale of 2-4 years. OBC and ATM were secondary factors contributing to the interannual variation of surface circulation. Interannual variation of ATM changed the separation latitude of EKWC and increased the variability of surface circulation in the Ulleung Basin. Interannual variation of OBC enhanced low-frequency changes in surface circulation and eddies in the Yamato Basin. It also modulated basin-wide uniform oscillations of sea level. This study suggests that precise estimation of initial conditions using data assimilation is essential for long-term prediction of surface circulation in the JES.

Variations in the Availability of Pollen Resources Affect Honey Bee Health

PubMed Central

Di Pasquale, Garance; Alaux, Cédric; Le Conte, Yves; Odoux, Jean-François; Pioz, Maryline; Vaissière, Bernard E.; Belzunces, Luc P.; Decourtye, Axel

2016-01-01

Intensive agricultural systems often expose honey bees (Apis mellifera L.) to large temporal variations in the availability (quantity, quality and diversity) of nutritional resources. Such nutritional irregularity is expected to affect honey bee health. We therefore tested under laboratory conditions the effect of such variation in pollen availability on honey bee health (survival and nursing physiology—hypopharyngeal gland development and vitellogenin expression). We fed honey bees with different diets composed of pollen pellets collected by honey bees in an agricultural landscape of western France. Slight drops (5–10%) in the availability of oilseed rape (Brassica napus L.) pollen resulted in significant reductions of all tested variables. Despite some variations in taxonomic diversity and nutritional quality, the pollen mixes harvested over the season had a similar positive influence on honey bee health, except for the one collected in late July that induced poor survival and nursing physiology. This period coincided with the mass-flowering of maize (Zea mays L.), an anemophilous crop which produces poor-quality pollen. Therefore, changes in bee health were not connected to variations in pollen diversity but rather to variations in pollen depletion and quality, such as can be encountered in an intensive agricultural system of western France. Finally, even though pollen can be available ad libitum during the mass-flowering of some crops (e.g. maize), it can fail to provide bees with diet adequate for their development. PMID:27631605

Feasibility analysis of large length-scale thermocapillary flow experiment for the International Space Station

NASA Astrophysics Data System (ADS)

Alberts, Samantha J.

The investigation of microgravity fluid dynamics emerged out of necessity with the advent of space exploration. In particular, capillary research took a leap forward in the 1960s with regards to liquid settling and interfacial dynamics. Due to inherent temperature variations in large spacecraft liquid systems, such as fuel tanks, forces develop on gas-liquid interfaces which induce thermocapillary flows. To date, thermocapillary flows have been studied in small, idealized research geometries usually under terrestrial conditions. The 1 to 3m lengths in current and future large tanks and hardware are designed based on hardware rather than research, which leaves spaceflight systems designers without the technological tools to effectively create safe and efficient designs. This thesis focused on the design and feasibility of a large length-scale thermocapillary flow experiment, which utilizes temperature variations to drive a flow. The design of a helical channel geometry ranging from 1 to 2.5m in length permits a large length-scale thermocapillary flow experiment to fit in a seemingly small International Space Station (ISS) facility such as the Fluids Integrated Rack (FIR). An initial investigation determined the proposed experiment produced measurable data while adhering to the FIR facility limitations. The computational portion of this thesis focused on the investigation of functional geometries of fuel tanks and depots using Surface Evolver. This work outlines the design of a large length-scale thermocapillary flow experiment for the ISS FIR. The results from this work improve the understanding thermocapillary flows and thus improve technological tools for predicting heat and mass transfer in large length-scale thermocapillary flows. Without the tools to understand the thermocapillary flows in these systems, engineers are forced to design larger, heavier vehicles to assure safety and mission success.

Identifying suitable substrates for high-quality graphene-based heterostructures

NASA Astrophysics Data System (ADS)

Banszerus, L.; Janssen, H.; Otto, M.; Epping, A.; Taniguchi, T.; Watanabe, K.; Beschoten, B.; Neumaier, D.; Stampfer, C.

2017-06-01

We report on a scanning confocal Raman spectroscopy study investigating the strain-uniformity and the overall strain and doping of high-quality chemical vapour deposited (CVD) graphene-based heterostuctures on a large number of different substrate materials, including hexagonal boron nitride (hBN), transition metal dichalcogenides, silicon, different oxides and nitrides, as well as polymers. By applying a hBN-assisted, contamination free, dry transfer process for CVD graphene, high-quality heterostructures with low doping densities and low strain variations are assembled. The Raman spectra of these pristine heterostructures are sensitive to substrate-induced doping and strain variations and are thus used to probe the suitability of the substrate material for potential high-quality graphene devices. We find that the flatness of the substrate material is a key figure for gaining, or preserving high-quality graphene.

Direct observation of strain-induced orbital valence band splitting in HfSe2 by sodium intercalation

NASA Astrophysics Data System (ADS)

Eknapakul, T.; Fongkaew, I.; Siriroj, S.; Jindata, W.; Chaiyachad, S.; Mo, S.-K.; Thakur, S.; Petaccia, L.; Takagi, H.; Limpijumnong, S.; Meevasana, W.

2018-05-01

By using angle-resolved photoemission spectroscopy (ARPES), the variation of the electronic structure of HfSe2 has been studied as a function of sodium intercalation. We observe how this drives a band splitting of the p -orbital valence bands and a simultaneous reduction of the indirect band gap by values of up to 400 and 280 meV, respectively. Our calculations indicate that such behavior is driven by the band deformation potential, which is a result of our observed strain induced by sodium intercalation. The applied uniaxial strain calculations based on density functional theory agree strongly with the experimental ARPES data. These findings should assist in studying the physical relationship between intercalation and strain, as well as for large-scale two-dimensional straintronics.

En route noise levels from propfan test assessment airplane

NASA Technical Reports Server (NTRS)

Garber, Donald P.; Willshire, William L., Jr.

1994-01-01

The en route noise test was designed to characterize propagation of propfan noise from cruise altitudes to the ground. In-flight measurements of propfan source levels and directional patterns were made by a chase plane flying in formation with the propfan test assessment (PTA) airplane. Ground noise measurements were taken during repeated flights over a distributed microphone array. The microphone array on the ground was used to provide ensemble-averaged estimates of mean flyover noise levels, establish confidence limits for those means, and measure propagation-induced noise variability. Even for identical nominal cruise conditions, peak sound levels for individual overflights varied substantially about the average, particularly when overflights were performed on different days. Large day-to-day variations in peak level measurements appeared to be caused by large day-to-day differences in propagation conditions and tended to obscure small variations arising from operating conditions. A parametric evaluation of the sensitivity of this prediction method to weather measurement and source level uncertainties was also performed. In general, predictions showed good agreement with measurements. However, the method was unable to predict short-term variability of ensemble-averaged data within individual overflights. Although variations in absorption appear to be the dominant factor in variations of peak sound levels recorded on the ground, accurate predictions of those levels require that a complete description of operational conditions be taken into account. The comprehensive and integrated methods presented in this paper have adequately predicted ground-measured sound levels. On average, peak sound levels were predicted within 3 dB for each of the three different cruise conditions.

Physics based model of D-region variability related to VLF propagation effects

NASA Astrophysics Data System (ADS)

Chakravarty, S. C.

2012-07-01

D-region (~60-85 km) electron density profiles measured using large number of sounding rocket experiments carried out from two Indian low latitude stations show large variations with solar zenith angle, season and solar activity. Similarly the ground based multi frequency radio wave absorption technique has provided continuous data on the morphology of the hourly electron density variations. However suitable models of the D-region electron density profile variations both during quiet and disturbed solar conditions over the Indian region are lacking. The renewed interest in the study of the VLF/LF propagation anomalies taking place through perturbations in the D-region electron densities due to various geophysical phenomena requires the availability of a baseline D-region model over low latitudes. The purpose of this paper is to critically review the physical processes of D-region production and loss of free electrons, dynamical coupling due to variety of vertically propagating atmospheric waves, sudden changes brought about by the solar energetic events like CMEs and different categories of X-ray flares. Low latitude region is not likely to be affected by the PMSE or PCA type of events but the changes due to lightning induced mesospheric red sprites and LEPs need to be considered. Based on this analysis, a preliminary low latitude D-region electron density profile model development is proposed. Sample results would illustrate key requirements from such a model in terms of its effectiveness to simulate the low latitude observations of VLF/LF amplitude and phase variations using waveguide propagation models like LWPC.

Numerical modeling of an estuary: A comprehensive skill assessment

USGS Publications Warehouse

Warner, J.C.; Geyer, W.R.; Lerczak, J.A.

2005-01-01

Numerical simulations of the Hudson River estuary using a terrain-following, three-dimensional model (Regional Ocean Modeling System (ROMS)) are compared with an extensive set of time series and spatially resolved measurements over a 43 day period with large variations in tidal forcing and river discharge. The model is particularly effective at reproducing the observed temporal variations in both the salinity and current structure, including tidal, spring neap, and river discharge-induced variability. Large observed variations in stratification between neap and spring tides are captured qualitatively and quantitatively by the model. The observed structure and variations of the longitudinal salinity gradient are also well reproduced. The most notable discrepancy between the model and the data is in the vertical salinity structure. While the surface-to-bottom salinity difference is well reproduced, the stratification in the model tends to extend all the way to the water surface, whereas the observations indicate a distinct pycnocline and a surface mixed layer. Because the southern boundary coindition is located near the mouth the estuary, the salinity within the domain is particularly sensitive to the specification of salinity at the boundary. A boundary condition for the horizontal salinity gradient, based on the local value of salinity, is developed to incorporate physical processes beyond the open boundary not resolved by the model. Model results are sensitive to the specification of the bottom roughness length and vertical stability functions, insofar as they influence the intensity of vertical mixing. The results only varied slightly between different turbulence closure methods of k-??, k-??, and k-kl. Copyright 2005 by the American Geophysical Union.

The Contribution of Reservoirs to Global Land Surface Water Storage Variations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Tian; Nijssen, Bart; Gao, Huilin

Man-made reservoirs play a key role in the terrestrial water system. They alter water fluxes at the land surface and impact surface water storage through water management regulations for diverse purposes such as irrigation, municipal water supply, hydropower generation, and flood control. Although most developed countries have established sophisticated observing systems for many variables in the land surface water cycle, long-term and consistent records of reservoir storage are much more limited and not always shared. Furthermore, most land surface hydrological models do not represent the effects of water management activities. Here, the contribution of reservoirs to seasonal water storage variationsmore » is investigated using a large-scale water management model to simulate the effects of reservoir management at basin and continental scales. The model was run from 1948 to 2010 at a spatial resolution of 0.258 latitude–longitude. A total of 166 of the largest reservoirs in the world with a total capacity of about 3900 km3 (nearly 60%of the globally integrated reservoir capacity) were simulated. The global reservoir storage time series reflects the massive expansion of global reservoir capacity; over 30 000 reservoirs have been constructed during the past half century, with a mean absolute interannual storage variation of 89 km3. The results indicate that the average reservoir-induced seasonal storage variation is nearly 700 km3 or about 10%of the global reservoir storage. For some river basins, such as the Yellow River, seasonal reservoir storage variations can be as large as 72%of combined snow water equivalent and soil moisture storage.« less

Surface-induced brightness temperature variations and their effects on detecting thin cirrus clouds using IR emission channels in the 8-12 microns region

NASA Technical Reports Server (NTRS)

Gao, Bo-Cai; Wiscombe, W. J.

1994-01-01

A method for detecting cirrus clouds in terms of brightness temperature differences between narrowbands at 8, 11, and 12 microns has been proposed by Ackerman et al. In this method, the variation of emissivity with wavelength for different surface targets was not taken into consideration. Based on state-of-the-art laboratory measurements of reflectance spectra of terrestrial materials by Salisbury and D'Aria, it is found that the brightness temperature differences between the 8- and 11-microns bands for soils, rocks, and minerals, and dry vegetation can vary between approximately -8 and +8 K due solely to surface emissivity variations. The large brightness temperature differences are sufficient to cause false detection of cirrus clouds from remote sensing data acquired over certain surface targets using the 8-11-12-microns method directly. It is suggested that the 8-11-12-microns method should be improved to include the surface emissivity effects. In addition, it is recommended that in the future the variation of surface emissivity with wavelength should be taken into account in algorithms for retrieving surface temperatures and low-level atmospheric temperature and water vapor profiles.

Genetic variation for susceptibility to storm-induced stem breakage in Solidago altissima: The role of stem height and morphology

NASA Astrophysics Data System (ADS)

Wise, Michael J.; Abrahamson, Warren G.

2010-07-01

While storms can have obvious ecological impacts on plants, plants' potential to respond evolutionarily to selection for increased resistance to storm damage has received little study. We took advantage of a thunderstorm with strong wind and hail to examine genetic variation for resistance to stem breakage in the herbaceous perennial Solidago altissima. The storm broke the apex of nearly 10% of 1883 marked ramets in a common-garden plot containing 26 genets of S. altissima. Plant genets varied 20-fold in resistance to breakage. Stem height was strongly correlated with resistance to breakage, with taller stems being significantly more susceptible. A stem's growth form (erect versus nodding) had no detectable effect on its resistance to breakage. Therefore, we rejected the hypothesis that a function of the nodding, or "candy-cane," morphology is protection of the apex from storm damage. The significant genetic variation in S. altissima for stem breakage suggests that this plant has the capacity to respond to selection imposed by storms - particularly through changes in mean stem height. Tradeoffs between breakage resistance and competition for light and pollinators may act to maintain a large amount of genetic variation in stem height.

Near infrared spectroscopy based monitoring of extraction processes of raw material with the help of dynamic predictive modeling

NASA Astrophysics Data System (ADS)

Wang, Haixia; Suo, Tongchuan; Wu, Xiaolin; Zhang, Yue; Wang, Chunhua; Yu, Heshui; Li, Zheng

2018-03-01

The control of batch-to-batch quality variations remains a challenging task for pharmaceutical industries, e.g., traditional Chinese medicine (TCM) manufacturing. One difficult problem is to produce pharmaceutical products with consistent quality from raw material of large quality variations. In this paper, an integrated methodology combining the near infrared spectroscopy (NIRS) and dynamic predictive modeling is developed for the monitoring and control of the batch extraction process of licorice. With the spectra data in hand, the initial state of the process is firstly estimated with a state-space model to construct a process monitoring strategy for the early detection of variations induced by the initial process inputs such as raw materials. Secondly, the quality property of the end product is predicted at the mid-course during the extraction process with a partial least squares (PLS) model. The batch-end-time (BET) is then adjusted accordingly to minimize the quality variations. In conclusion, our study shows that with the help of the dynamic predictive modeling, NIRS can offer the past and future information of the process, which enables more accurate monitoring and control of process performance and product quality.

The effect of vocal fold vertical stiffness gradient on sound production

NASA Astrophysics Data System (ADS)

Geng, Biao; Xue, Qian; Zheng, Xudong

2015-11-01

It is observed in some experimental studies on canine vocal folds (VFs) that the inferior aspect of the vocal fold (VF) is much stiffer than the superior aspect under relatively large strain. Such vertical difference is supposed to promote the convergent-divergent shape during VF vibration and consequently facilitate the production of sound. In this study, we investigate the effect of vertical variation of VF stiffness on sound production using a numerical model. The vertical variation of stiffness is produced by linearly increasing the Young's modulus and shear modulus from the superior to inferior aspects in the cover layer, and its effect on phonation is examined in terms of aerodynamic and acoustic quantities such as flow rate, open quotient, skewness of flow wave form, sound intensity and vocal efficiency. The flow-induced vibration of the VF is solved with a finite element solver coupled with 1D Bernoulli equation, which is further coupled with a digital waveguide model. This study is designed to find out whether it's beneficial to artificially induce the vertical stiffness gradient by certain implanting material in VF restoring surgery, and if it is beneficial, what gradient is the most favorable.

Comparative biogeochemistry-ecosystem-human interactions on dynamic continental margins

USGS Publications Warehouse

Levin, Lisa A.; Liu, Kon-Kee; Emeis, Kay-Christian; Breitburg, Denise L.; Cloern, James; Deutsch, Curtis; Giani, Michele; Goffart, Anne; Hofmann, Eileen E.; Lachkar, Zouhair; Limburg, Karin; Liu, Su-Mei; Montes, Enrique; Naqvi, Wajih; Ragueneau, Olivier; Rabouille, Christophe; Sarkar, Santosh Kumar; Swaney, Dennis P.; Wassman, Paul; Wishner, Karen F.

2014-01-01

The ocean’s continental margins face strong and rapid change, forced by a combination of direct human activity, anthropogenic CO2-induced climate change, and natural variability. Stimulated by discussions in Goa, India at the IMBER IMBIZO III, we (1) provide an overview of the drivers of biogeochemical variation and change on margins, (2) compare temporal trends in hydrographic and biogeochemical data across different margins (3) review ecosystem responses to these changes, (4) highlight the importance of margin time series for detecting and attributing change and (5) examine societal responses to changing margin biogeochemistry and ecosystems. We synthesize information over a wide range of margin settings in order to identify the commonalities and distinctions among continental margin ecosystems. Key drivers of biogeochemical variation include long-term climate cycles, CO2-induced warming, acidification, and deoxygenation, as well as sea level rise, eutrophication, hydrologic and water cycle alteration, changing land use, fishing, and species invasion. Ecosystem responses are complex and impact major margin services including primary production, fisheries production, nutrient cycling, shoreline protection, chemical buffering, and biodiversity. Despite regional differences, the societal consequences of these changes are unarguably large and mandate coherent actions to reduce, mitigate and adapt to multiple stressors on continental margins.

Comparative biogeochemistry-ecosystem-human interactions on dynamic continental margins

NASA Astrophysics Data System (ADS)

Levin, Lisa A.; Liu, Kon-Kee; Emeis, Kay-Christian; Breitburg, Denise L.; Cloern, James; Deutsch, Curtis; Giani, Michele; Goffart, Anne; Hofmann, Eileen E.; Lachkar, Zouhair; Limburg, Karin; Liu, Su-Mei; Montes, Enrique; Naqvi, Wajih; Ragueneau, Olivier; Rabouille, Christophe; Sarkar, Santosh Kumar; Swaney, Dennis P.; Wassman, Paul; Wishner, Karen F.

2015-01-01

The oceans' continental margins face strong and rapid change, forced by a combination of direct human activity, anthropogenic CO2-induced climate change, and natural variability. Stimulated by discussions in Goa, India at the IMBER IMBIZO III, we (1) provide an overview of the drivers of biogeochemical variation and change on margins, (2) compare temporal trends in hydrographic and biogeochemical data across different margins, (3) review ecosystem responses to these changes, (4) highlight the importance of margin time series for detecting and attributing change and (5) examine societal responses to changing margin biogeochemistry and ecosystems. We synthesize information over a wide range of margin settings in order to identify the commonalities and distinctions among continental margin ecosystems. Key drivers of biogeochemical variation include long-term climate cycles, CO2-induced warming, acidification, and deoxygenation, as well as sea level rise, eutrophication, hydrologic and water cycle alteration, changing land use, fishing, and species invasion. Ecosystem responses are complex and impact major margin services. These include primary production, fisheries production, nutrient cycling, shoreline protection, chemical buffering, and biodiversity. Despite regional differences, the societal consequences of these changes are unarguably large and mandate coherent actions to reduce, mitigate and adapt to multiple stressors on continental margins.

Solar Sail Topology Variations Due to On-Orbit Thermal Effects

NASA Technical Reports Server (NTRS)

Banik, Jeremy A.; Lively, Peter S.; Taleghani, Barmac K.; Jenkins, Chrostopher H.

2006-01-01

The objective of this research was to predict the influence of non-uniform temperature distribution on solar sail topology and the effect of such topology variations on sail performance (thrust, torque). Specifically considered were the thermal effects due to on orbit attitude control maneuvers. Such maneuvers are expected to advance the sail to a position off-normal to the sun by as much as 35 degrees; a solar sail initially deformed by typical pre-tension and solar pressure loads may suffer significant thermally induced strains due to the non-uniform heating caused by these maneuvers. This on-orbit scenario was investigated through development of an automated analytical shape model that iterates many times between sail shape and sail temperature distribution before converging on a final coupled thermal structural affected sail topology. This model utilizes a validated geometrically non-linear finite element model and a thermal radiation subroutine. It was discovered that temperature gradients were deterministic for the off-normal solar angle cases as were thermally induced strains. Performance effects were found to be moderately significant but not as large as initially suspected. A roll torque was detected, and the sail center of pressure shifted by a distance that may influence on-orbit sail control stability.

The role of niobium carbide in radiation induced segregation behaviour of type 347 austenitic stainless steel

NASA Astrophysics Data System (ADS)

Ahmedabadi, Parag; Kain, Vivekanand; Gupta, Manu; Samajdar, I.; Sharma, S. C.; Bhagwat, P.; Chowdhury, R.

2011-08-01

The effect of niobium carbide precipitates on radiation induced segregation (RIS) behaviour in type 347 stainless steel was investigated. The material in the as-received condition was irradiated using double-loop 4.8 MeV protons at 300 °C for 0.43 dpa (displacement per atom). The RIS in the proton irradiated specimen was characterized using double-loop electrochemical potentiokinetic reactivation (DL-EPR) test followed by atomic force microscopic examination. The nature of variation of DL-EPR values with the depth matched with the variation of the calculated irradiation damage (dpa) with the depth. The attack on grain boundaries during EPR tests was negligible indicating absence of chromium depletion zones. The interface between niobium carbide and the matrix acts as a sink for point defects generated during irradiation and this had reduced point defect flux toward grain boundaries. The attack was noticed at a few large cluster of niobium carbide after the DL-EPR test at the depth of maximum attack for the irradiated specimen. Pit-like features were not observed within the matrix indicating the absence of chromium depletion regions within the matrix.

Carbon recycling in deltaic sediments: variations at different timescales in the Rhone River delta

NASA Astrophysics Data System (ADS)

Rabouille, C.; Rassmann, J.; Toussaint, F.; Cathalot, C.; Tisnerat-Laborde, N.; Lansard, B.

2016-02-01

Terrestrial aquatic environments and the land-sea connection are a major contributors to the Earth carbon cycle, as these act as a source to the atmosphere of about 1 Gt/yr for rivers and up to 0.4 Gt/yr for estuarine/detaic systems. These estimates are largely uncertain because of the large temporal variability of these systems. In estuarine and deltaic sediments, variability combines hydrological variation from the river (floods and drought) and the hydrology of the coastal seas (storms, current surge, wind induced circulation, upwelling) wich are both influencial on biogeochemistry. This hydrological variability interacts with the seasonal variation of in situ production and with thermal activation of bacterial recycling due to seasonal warming of shallow waters. The combination of these processes gives rise to a range of timescales: typically hours to days for resuspension during storms to interannual variations for particulate discharge modulations. Using in situ oxygen microprofiling devices, we have collected a new dataset on organic matter recycling in the Rhone delta and shelf sediments (Northwestern Mediterranean Sea) which covers a wide range of timescales: from hours to a decade. The hourly variation is collected using a new benthic station deployed on the sediments and specially adapted to monitor short-term variations of sediment oxygen micro-profiles during flood or storms. The seasonal to decadal timescale is constituted by a set of oxygen micro-profiles measured on an array of stations in the Rhône prodelta and shelf by an in situ microprofiler during seasonal cruises over 10 year. The results show that Diffusive Oxygen Fluxes which are related to organic matter recycling vary at all timescales, driven mostly by deposition of river material during floods. Resuspension during storms plays a role over short time scales, and its long-term effect could raise the overall oxygen demand of the sediment by 20-30%.

Climate Impacts of Fire-Induced Land-Surface Changes

NASA Astrophysics Data System (ADS)

Liu, Y.; Hao, X.; Qu, J. J.

2017-12-01

One of the consequences of wildfires is the changes in land-surface properties such as removal of vegetation. This will change local and regional climate through modifying the land-air heat and water fluxes. This study investigates mechanism by developing and a parameterization of fire-induced land-surface property changes and applying it to modeling of the climate impacts of large wildfires in the United States. Satellite remote sensing was used to quantitatively evaluate the land-surface changes from large fires provided from the Monitoring Trends in Burning Severity (MTBS) dataset. It was found that the changes in land-surface properties induced by fires are very complex, depending on vegetation type and coverage, climate type, season and time after fires. The changes in LAI are remarkable only if the actual values meet a threshold. Large albedo changes occur in winter for fires in cool climate regions. The signs are opposite between the first post-fire year and the following years. Summer day-time temperature increases after fires, while nigh-time temperature changes in various patterns. The changes are larger in forested lands than shrub / grassland lands. In the parameterization scheme, the detected post-fire changes are decomposed into trends using natural exponential functions and fluctuations of periodic variations with the amplitudes also determined by natural exponential functions. The final algorithm is a combination of the trends, periods, and amplitude functions. This scheme is used with Earth system models to simulate the local and regional climate effects of wildfires.

Giant electrocaloric effect in a cracked ferroelectrics

NASA Astrophysics Data System (ADS)

Huang, Cheng; Yang, Hai-Bing; Gao, Cun-Fa

2018-04-01

The electrocaloric effect (ECE) is the temperature change in a material induced by electrical field variation under adiabatic condition. Considering an external electric load applied on a cracked ferroelectric solid, a non-uniform electric field would be induced at the crack tip, and thus, incompatible strain field and local stress concentration would be generated around it. Furthermore, the enormous strain energy and the electrostatic energy would affect the polarization switching of the ferroelectric solid, important for the electrocaloric response. In this paper, the large negative and positive ECEs in a ferroelectric sheet with a conducting crack are investigated by the phase field method with the consideration of time-dependent Ginzburg-Landau equation. The numerical calculations indicated that the polarization field generates a sharp rise during the domain transition from polydomain to monodomain under a certain electric load. Large negative ECEs, about -10.21 K and -7.55 K, are obtained at 135 °C and 85 °C, respectively. The domain transition temperature is much lower than the Curie temperature, which enlarges the existence scope of the large ECE in ferroelectrics. The results also imply that the domain transition from a multi-domain state to a single domain takes place with the minimization of total free energy, which involves the courses of the electric field, stress field, temperature, and polarization interaction. Therefore, the non-uniform distributions of the stress-electric fields induced by the crack play an important role in ECE.

Phase demodulation of Fabry-Perot interferometer-based acoustic sensor utilizing tunable filter with two quadrature wavelengths

NASA Astrophysics Data System (ADS)

Liao, Hao; Lu, Ping; Liu, Li; Liu, Deming; Zhang, Jiangshan

2017-02-01

A phase demodulation method for short-cavity extrinsic Fabry-Perot interferometer (EFPI) based on two orthogonal wavelengths via a tunable optical filter is proposed in this paper. A broadband light is launched into the EFPI sensor and two monochromatic beams with 3dB bandwidth of 0.2nm are selected out from the reflected light of the EFPI sensor. A phase bias is induced between the two interferential signals due to the wavelength difference of the two beams. The wavelength difference will have an affect on the sensitivity of demodulated signal, which has been theoretically and experimentally demonstrated. The maximum sensitivity can be obtained when the phase bias is 0.5π corresponding to the wavelength difference of 1/4 FSR of the EFPI spectrum. The acoustic wave induced phase variation can be interrogated through an optimized differential cross multiplication (DCM) method. A normalization process is induced into the traditional DCM method to eliminate the influence of ambient temperature and pressure fluctuation induced spectrum shift on output signal. This means that, once the wavelength difference is fixed, the wavelength variation of each individual beam will have little influence on the amplitude of demodulated signal. The EFPI sensing head is formed by a 3μm-thick aluminum diaphragm, which has a SNR of more than 53dB. Through the proposed demodulation scheme, a large dynamic range and good linearity is acquired and Q-point drift problem of traditional EFPI sensor can be solved. The demodulation scheme can be applied to other kinds of short-cavity EFPI based acoustic sensors.

Laser-induced plasmonic colours on metals

NASA Astrophysics Data System (ADS)

Guay, Jean-Michel; Calà Lesina, Antonino; Côté, Guillaume; Charron, Martin; Poitras, Daniel; Ramunno, Lora; Berini, Pierre; Weck, Arnaud

2017-07-01

Plasmonic resonances in metallic nanoparticles have been used since antiquity to colour glasses. The use of metal nanostructures for surface colourization has attracted considerable interest following recent developments in plasmonics. However, current top-down colourization methods are not ideally suited to large-scale industrial applications. Here we use a bottom-up approach where picosecond laser pulses can produce a full palette of non-iridescent colours on silver, gold, copper and aluminium. We demonstrate the process on silver coins weighing up to 5 kg and bearing large topographic variations (~1.5 cm). We find that colours are related to a single parameter, the total accumulated fluence, making the process suitable for high-throughput industrial applications. Statistical image analyses of laser-irradiated surfaces reveal various nanoparticle size distributions. Large-scale finite-difference time-domain computations based on these nanoparticle distributions reproduce trends seen in reflectance measurements, and demonstrate the key role of plasmonic resonances in colour formation.

Laser-induced plasmonic colours on metals

PubMed Central

Guay, Jean-Michel; Calà Lesina, Antonino; Côté, Guillaume; Charron, Martin; Poitras, Daniel; Ramunno, Lora; Berini, Pierre; Weck, Arnaud

2017-01-01

Plasmonic resonances in metallic nanoparticles have been used since antiquity to colour glasses. The use of metal nanostructures for surface colourization has attracted considerable interest following recent developments in plasmonics. However, current top-down colourization methods are not ideally suited to large-scale industrial applications. Here we use a bottom-up approach where picosecond laser pulses can produce a full palette of non-iridescent colours on silver, gold, copper and aluminium. We demonstrate the process on silver coins weighing up to 5 kg and bearing large topographic variations (∼1.5 cm). We find that colours are related to a single parameter, the total accumulated fluence, making the process suitable for high-throughput industrial applications. Statistical image analyses of laser-irradiated surfaces reveal various nanoparticle size distributions. Large-scale finite-difference time-domain computations based on these nanoparticle distributions reproduce trends seen in reflectance measurements, and demonstrate the key role of plasmonic resonances in colour formation. PMID:28719576

Human iPSC-derived neurons and lymphoblastoid cells for personalized medicine research in neuropsychiatric disorders.

PubMed

Gurwitz, David

2016-09-01

The development and clinical implementation of personalized medicine crucially depends on the availability of high-quality human biosamples; animal models, although capable of modeling complex human diseases, cannot reflect the large variation in the human genome, epigenome, transcriptome, proteome, and metabolome. Although the biosamples available from public biobanks that store human tissues and cells may represent the large human diversity for most diseases, these samples are not always sufficient for developing biomarkers for patient-tailored therapies for neuropsychiatric disorders. Postmortem human tissues are available from many biobanks; nevertheless, collections of neuronal human cells from large patient cohorts representing the human diversity remain scarce. Two tools are gaining popularity for personalized medicine research on neuropsychiatric disorders: human induced pluripotent stem cell-derived neurons and human lymphoblastoid cell lines. This review examines and contrasts the advantages and limitations of each tool for personalized medicine research.

Isothermal lipid phase transitions.

PubMed

Cevc, G

1991-03-01

In liotropic lipid systems phase transitions can be induced isothermally by changing the solvent concentration or composition; alternatively, lipid composition can be modified by (bio)chemical means. The probability for isothermal phase transitions increases with the decreasing transition entropy; it is proportional to the magnitude of the transition temperature shift caused by transformation-inducing system variation. Manipulations causing large thermodynamic effects, such as lipid (de)hydration, binding of protons or divalent ions and macromolecular adsorption, but also close bilayer approach are, therefore, likely to cause structural lipid change(s) at a constant temperature. Net lipid charges enhance the membrane susceptibility to salt-induced isothermal phase transitions; a large proportion of this effect is due to the bilayer dehydration, however, rather than being a consequence of the decreased Coulombic electrostatic interactions. Membrane propensity for isothermal phase transitions, consequently, always increases with the hydrophilicity of the lipid heads, as well as with the desaturation and shortening of the lipid chains. Upon a phase change at a constant temperature, some of the interfacially bound solutes (e.g. protons or calcium) are released in the solution. Membrane permeability and fusogenicity simultaneously increase. In mixed systems, isothermal phase transitions, moreover, may result in lateral phase separation. All this opens up ways for the involvement of isothermal phase transitions in the regulation of biological processes.

Electromagnetic induced voltage signal to magnetic variation through torquing textured Fe81Ga19 alloy

NASA Astrophysics Data System (ADS)

Li, Mingming; Li, Jiheng; Bao, Xiaoqian; Mu, Xing; Gao, Xuexu

2017-07-01

The results of a study on the suitability of Fe-Ga alloys for torque sensor applications are presented. A Fe81Ga19 rod with a ⟨100⟩ preferred orientation along the length direction is prepared for the torque shaft and as the electromagnetic induction sensitive element, which is wound with three coils for signal excitation, signal pickup, and applied bias magnetic field, respectively. An apparent decrease in the induced voltage signal (peak voltage) of 3.88 mV is observed as the torque loading is 50 N m in the presence of a sine excitation signal (10 V, 1 kHz) and a bias current of 0.5 A. Meanwhile, a good repeatability and stress sensitivity are obtained, especially in the low torque range. These behaviors stem from the stress induced decrease in the magnetic permeability and the rotation of the arranged magnetic moment. Here, we use the Fe81Ga19 alloy as the shaft material; nevertheless, in practical use, the same effect can be achieved by forming a Fe-Ga layer with large magnetostriction on the surface of the torsion shaft. This work shows the prospect of Fe-Ga alloys for non-contact torque sensing, for the large magnetostriction and high sensitivity of magnetization to stress.

Storm generated large scale TIDs (LSTIDs): local, regional and global observations during solar cycles 23-24

NASA Astrophysics Data System (ADS)

Katamzi, Zama; Bosco Habarulema, John

2017-04-01

Large scale traveling ionospheric disturbances (LSTIDs) are a key dynamic ionospheric process that transports energy and momentum vertically and horizontally during storms. These disturbances are observed as electron density irregularities in total electron content and other ionospheric parameters. This study reports on various explorations of LSTIDs characteristics, in particular horizontal and vertical propagation, during some major/severe storms of solar cycles 23-24. We have employed GNSS TEC to estimate horizontal propagation and radio occultation data from COSMIC/FORMOSAT-3 and SWARM satellites to estimate vertical motion. The work presented here reveals the evolution of the characterisation efficiency from using sparsely populated stations, resulting in limited spatial resolution through rudimentary analysis to more densely populated GNSS network leading to more accurate temporal and spatial determinations. For example, early observations of LSTIDs largely revealed unidirectional propagation whereas later studies have showed that one storm can induce multi-directional propagation, e.g. Halloween 2003 storm induced equatorward LSTIDs on a local scale whereas the 9 March 2012 storm induced simultaneous equatorward and poleward LSTIDs on a global scale. This later study, i.e. 9 March 2012 storm, revealed for the first time that ionospheric electrodynamics, specifically variations in ExB drift, is also an efficient generator of LSTIDs. Results from these studies also revealed constructive and destructive interference pattern of storm induced LSTIDs. Constellations of LEO satellites such as COSMIC/FORMOSAT-3 and SWARM have given sufficient spatial and temporal resolution to study vertical propagation of LSTIDs in addition to the meridional propagation given by GNSS TEC; the former (i.e. vertical velocities) were found to fall below 100 m/s.

In Forests Globally, Large Trees Suffer Most during Drought

NASA Astrophysics Data System (ADS)

Bennett, A. C.; McDowell, N. G.; Allen, C. D.; Anderson-Teixeira, K. J.

2014-12-01

Globally, drought events are increasing in both frequency and intensity. Spatial and temporal variation in water availability is expected to alter the ecophysiology and structure of forests, with consequent feedbacks to climate change. Extensive tree mortality induced by heat and aridity has been documented across a range of latitudes, and several global vegetation models have simulated widespread forest die-off in the future. The impact of drought on forest structure and function will depend on the differential responses of trees of different sizes. Understanding the size-dependence of drought-induced mortality is necessary to predict local and global impacts. Here we show that in forests worldwide, drought has a greater impact on the growth and mortality of large trees compared to smaller trees. This trend holds true for forests ranging from semiarid woodlands to tropical rainforests. This finding contrasts with what would be expected if deep root access to water were the primary determinant of tree drought response. Rather, the greater drought response of larger trees could be driven by greater inherent vulnerability of large trees to hydraulic stress or by canopy position becoming more of a liability under drought, as exposed crowns face higher evaporative demand. These findings imply that future droughts will have a disproportionate effect on large trees, resulting in a larger feedback to climate change than would occur if all tree size classes were equally affected by drought.

Natural variation in gene expression in the early development of dauer larvae of Caenorhabditis elegans.

PubMed

Harvey, Simon C; Barker, Gary L A; Shorto, Alison; Viney, Mark E

2009-07-18

The free-living nematode Caenorhabditis elegans makes a developmental decision based on environmental conditions: larvae either arrest as dauer larva, or continue development into reproductive adults. There is natural variation among C. elegans lines in the sensitivity of this decision to environmental conditions; that is, there is variation in the phenotypic plasticity of dauer larva development. We hypothesised that these differences may be transcriptionally controlled in early stage larvae. We investigated this by microarray analysis of different C. elegans lines under different environmental conditions, specifically the presence and absence of dauer larva-inducing pheromone. There were substantial transcriptional differences between four C. elegans lines under the same environmental conditions. The expression of approximately 2,000 genes differed between genetically different lines, with each line showing a largely line-specific transcriptional profile. The expression of genes that are markers of larval moulting suggested that the lines may be developing at different rates. The expression of a total of 89 genes was putatively affected by dauer larva or non-dauer larva-inducing conditions. Among the upstream regions of these genes there was an over-representation of DAF-16-binding motifs. Under the same environmental conditions genetically different lines of C. elegans had substantial transcriptional differences. This variation may be due to differences in the developmental rates of the lines. Different environmental conditions had a rather smaller effect on transcription. The preponderance of DAF-16-binding motifs upstream of these genes was consistent with these genes playing a key role in the decision between development into dauer or into non-dauer larvae. There was little overlap between the genes whose expression was affected by environmental conditions and previously identified loci involved in the plasticity of dauer larva development.

Seafloor tilt induced by ocean tidal loading inferred from broadband seismometer data from the Cascadia subduction zone and Juan de Fuca Ridge

NASA Astrophysics Data System (ADS)

Davis, Earl E.; Heesemann, Martin; Lambert, Anthony; He, Jianheng

2017-04-01

Mass-balancing voltages from four buried broadband seismometers connected to the NEPTUNE Canada seafloor cable are being recorded at 24-bit resolution. Sites are located on the Vancouver Island continental shelf, the nearby Cascadia accretionary prism, the eastern flank of the Juan de Fuca Ridge, and the western flank close to the Juan de Fuca Ridge axis. Tidal variations are present throughout the records. Variations in vertical acceleration at three of the sites match predicted gravitational attraction variations very well; those at the fourth site show a small residual that is probably caused by sensitivity to tilt resulting from sensor inclination. Horizontal accelerations, which at tidal periods are sensitive primarily to tilt, are anomalously large relative to standard-earth model results. After removal of predicted tidal body and ocean attraction and loading terms, the residuals are seen to follow ocean pressure variations. Responses range from 0.4 μrad dbar-1 (0.04 μrad kPa-1) at 10° true (down under positive load) at the continental shelf site, to 0.6 μrad dbar-1 at 243° at the Cascadia prism, 0.4 μrad dbar-1 at 90° at the eastern Juan de Fuca Ridge flank, and 0.2 μrad dbar-1 at 116° true on the western ridge flank. Except at the continental shelf site, tilts are roughly perpendicular to structural strike. The tilt observations can be explained by loading-induced deformation in the presence of local lithologic gradients or by the influence of faults or structurally controlled anisotropic elastic properties. The observations highlight the utility of using mass position data from force-feedback broad-band seismometers for geodynamic studies.

Geographic Variation of Diapause and Sensitive Stages of Photoperiodic Response in Laodelphax striatellus Fallén (Hemiptera: Delphacidae)

PubMed Central

Hou, Yang-Yang; Xu, Lan-Zhen; Wu, Yan; Wang, Peng; Shi, Jin-Jian; Zhai, Bao-Ping

2016-01-01

Large numbers of the small brown planthopper Laodelphax striatellus (Fallén) (Hemiptera: Delphacidae) occur in temperate regions, causing severe losses in rice, wheat, and other economically important crops. The planthoppers enter diapause in the third- or fourth-instar nymph stage, induced by short photoperiods and low temperatures. To investigate the geographic variation in L. striatellus diapause, we compared the incidence of nymphal diapause under various constant temperature (20 and 27°C) and a photoperiod of 4:20, 8:16, 10:14, 12:12, 14:10, and 16:8 (L:D) h regimes among three populations collected from Hanoi (21.02° N, 105.85° E, northern Vietnam), Jiangyan (32.51° N, 120.15° E, eastern China), and Changchun (43.89° N, 125.32° E, north-eastern China). Our results indicated that there were significant geographic variations in the diapause of L. striatellus. When the original latitude of the populations increased, higher diapause incidence and longer critical photoperiod (CP) were exhibited. The CPs of the Jiangyan and Changchun populations were ∼12 hr 30 min and 13 hr at 20°C, and 11 hr and 11 hr 20 min at 27°C, respectively. The second- and third-instar nymphs were at the stage most sensitive to the photoperiod. However, when the fourth- and fifth-instar nymphs were transferred to a long photoperiod, the diapause-inducing effect of the short photoperiod on young instars was almost reversed. The considerable geographic variations in the nymphal diapause of L. striatellus reflect their adaptation in response to a variable environment and provide insights to develop effective pest management strategies. PMID:26839318

Millennial-scale Climate Variations Recorded As Far Back As The Early Pliocene

NASA Astrophysics Data System (ADS)

Steenbrink, J.; Hilgen, F. J.; Lourens, L. J.

Quaternary climate proxy records show compelling evidence for climate variability on time scales of a few thousand years. The causes for these millennial-scale or sub- Milankovitch cycles are yet poorly understood, not in the least due to the complex feedback mechanisms of large ice-sheets during the Quaternary. We present evidence of millennial-scale climate variability in Early Pliocene lacustrine sediments from the intramontane Ptolemais Basin in northwestern Greece. The sediments are well ex- posed in a series of open-pit lignite mines and exhibit a distinct m-scale sedimentary cyclicity of alternating lignites and lacustrine marl beds that result from precession- induced variations in climate. A higher-frequency cyclicity is particular prominent within the marl segment of individual cycles. A stratigraphic interval of~115 kyr, cov- ering five precession-induced sedimentary cycles, was studied in nine parallel sections from two quarries located several km apart. Colour reflectance records were used to quantify the within-cycle variability and to determine its lateral continuity. Much of the within-cycle variability could be correlated between the parallel sections, even in fine detail, which suggests that these changes reflect basin-wide variations in environ- mental conditions related to (regional) climate fluctuations. Interbedded volcanic ash beds demonstrate the synchronicity of these fluctuations and spectral analysis of the reflectance time series shows a significant concentration of variability at periods of ~11,~5.5 and~2 kyr. Their occurrence at times before the intensification of the North- ern Hemisphere glaciation suggests that they cannot solely have resulted from internal ice-sheet dynamics. Possible candidates include harmonics or combination tones of the main orbital cycles, variations in solar output or periodic motions of the Earth and moon.

Geographic Variation of Diapause and Sensitive Stages of Photoperiodic Response in Laodelphax striatellus Fallén (Hemiptera: Delphacidae).

PubMed

Hou, Yang-Yang; Xu, Lan-Zhen; Wu, Yan; Wang, Peng; Shi, Jin-Jian; Zhai, Bao-Ping

2016-01-01

Large numbers of the small brown planthopper Laodelphax striatellus (Fallén) (Hemiptera: Delphacidae) occur in temperate regions, causing severe losses in rice, wheat, and other economically important crops. The planthoppers enter diapause in the third- or fourth-instar nymph stage, induced by short photoperiods and low temperatures. To investigate the geographic variation in L. striatellus diapause, we compared the incidence of nymphal diapause under various constant temperature (20 and 27 °C) and a photoperiod of 4:20, 8:16, 10:14, 12:12, 14:10, and 16:8 (L:D) h regimes among three populations collected from Hanoi (21.02° N, 105.85° E, northern Vietnam), Jiangyan (32.51° N, 120.15° E, eastern China), and Changchun (43.89° N, 125.32° E, north-eastern China). Our results indicated that there were significant geographic variations in the diapause of L. striatellus. When the original latitude of the populations increased, higher diapause incidence and longer critical photoperiod (CP) were exhibited. The CPs of the Jiangyan and Changchun populations were ∼ 12 hr 30 min and 13 hr at 20 °C, and 11 hr and 11 hr 20 min at 27 °C, respectively. The second- and third-instar nymphs were at the stage most sensitive to the photoperiod. However, when the fourth- and fifth-instar nymphs were transferred to a long photoperiod, the diapause-inducing effect of the short photoperiod on young instars was almost reversed. The considerable geographic variations in the nymphal diapause of L. striatellus reflect their adaptation in response to a variable environment and provide insights to develop effective pest management strategies. © The Author 2016. Published by Oxford University Press on behalf of the Entomological Society of America.

Effects of Extreme Obliquity Variations on the Habitability of Exoplanets

PubMed Central

Barnes, R.; Domagal-Goldman, S.; Breiner, J.; Quinn, T.R.; Meadows, V.S.

2014-01-01

Abstract We explore the impact of obliquity variations on planetary habitability in hypothetical systems with high mutual inclination. We show that large-amplitude, high-frequency obliquity oscillations on Earth-like exoplanets can suppress the ice-albedo feedback, increasing the outer edge of the habitable zone. We restricted our exploration to hypothetical systems consisting of a solar-mass star, an Earth-mass planet at 1 AU, and 1 or 2 larger planets. We verified that these systems are stable for 108 years with N-body simulations and calculated the obliquity variations induced by the orbital evolution of the Earth-mass planet and a torque from the host star. We ran a simplified energy balance model on the terrestrial planet to assess surface temperature and ice coverage on the planet's surface, and we calculated differences in the outer edge of the habitable zone for planets with rapid obliquity variations. For each hypothetical system, we calculated the outer edge of habitability for two conditions: (1) the full evolution of the planetary spin and orbit and (2) the eccentricity and obliquity fixed at their average values. We recovered previous results that higher values of fixed obliquity and eccentricity expand the habitable zone, but we also found that obliquity oscillations further expand habitable orbits in all cases. Terrestrial planets near the outer edge of the habitable zone may be more likely to support life in systems that induce rapid obliquity oscillations as opposed to fixed-spin planets. Such planets may be the easiest to directly characterize with space-borne telescopes. Key Words: Exoplanets—Habitable zone—Energy balance models. Astrobiology 14, 277–291. PMID:24611714

Small-scale open ocean currents have large effects on wind wave heights

NASA Astrophysics Data System (ADS)

Ardhuin, Fabrice; Gille, Sarah T.; Menemenlis, Dimitris; Rocha, Cesar B.; Rascle, Nicolas; Chapron, Bertrand; Gula, Jonathan; Molemaker, Jeroen

2017-06-01

Tidal currents and large-scale oceanic currents are known to modify ocean wave properties, causing extreme sea states that are a hazard to navigation. Recent advances in the understanding and modeling capability of open ocean currents have revealed the ubiquitous presence of eddies, fronts, and filaments at scales 10-100 km. Based on realistic numerical models, we show that these structures can be the main source of variability in significant wave heights at scales less than 200 km, including important variations down to 10 km. Model results are consistent with wave height variations along satellite altimeter tracks, resolved at scales larger than 50 km. The spectrum of significant wave heights is found to be of the order of 70>>2/>(g2>>2>) times the current spectrum, where >> is the spatially averaged significant wave height, >> is the energy-averaged period, and g is the gravity acceleration. This variability induced by currents has been largely overlooked in spite of its relevance for extreme wave heights and remote sensing.