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Sample records for information system fis

  1. HyFIS: adaptive neuro-fuzzy inference systems and their application to nonlinear dynamical systems.

    PubMed

    Kim, J; Kasabov, N

    1999-11-01

    This paper proposes an adaptive neuro-fuzzy system, HyFIS (Hybrid neural Fuzzy Inference System), for building and optimising fuzzy models. The proposed model introduces the learning power of neural networks to fuzzy logic systems and provides linguistic meaning to the connectionist architectures. Heuristic fuzzy logic rules and input-output fuzzy membership functions can be optimally tuned from training examples by a hybrid learning scheme comprised of two phases: rule generation phase from data; and rule tuning phase using error backpropagation learning scheme for a neural fuzzy system. To illustrate the performance and applicability of the proposed neuro-fuzzy hybrid model, extensive simulation studies of nonlinear complex dynamic systems are carried out. The proposed method can be applied to an on-line incremental adaptive learning for the prediction and control of nonlinear dynamical systems. Two benchmark case studies are used to demonstrate that the proposed HyFIS system is a superior neuro-fuzzy modelling technique.

  2. Two Fis Regulators Directly Repress the Expression of Numerous Effector-Encoding Genes in Legionella pneumophila

    PubMed Central

    Zusman, Tal; Speiser, Yariv

    2014-01-01

    Legionella pneumophila is an intracellular human pathogen that utilizes the Icm/Dot type IVB secretion system to translocate a large repertoire of effectors into host cells. For most of these effectors, there is no information regarding their regulation. Therefore, the aim of this study was to examine the involvement of the three L. pneumophila Fis homologs in the regulation of effector-encoding genes. Deletion mutants constructed in the genes encoding the three Fis regulators revealed that Fis1 (lpg0542 gene) and Fis3 (lpg1743) but not Fis2 (lpg1370) are partially required for intracellular growth of L. pneumophila in Acanthamoeba castellanii. To identify pathogenesis-related genes directly regulated by Fis, we established a novel in vivo system which resulted in the discovery of numerous effector-encoding genes directly regulated by Fis. Further examination of these genes revealed that Fis1 and Fis3 repress the level of expression of effector-encoding genes during exponential phase. Three groups of effector-encoding genes were identified: (i) effectors regulated mainly by Fis1, (ii) effectors regulated mainly by Fis3, and (iii) effectors regulated by both Fis1 and Fis3. Examination of the upstream regulatory region of all of these effector-encoding genes revealed multiple putative Fis regulatory elements, and site-directed mutagenesis confirmed that a few of these sites constitute part of a repressor binding element. Furthermore, gel mobility shift assays demonstrated the direct relation between the Fis1 and Fis3 regulators and these regulatory elements. Collectively, our results demonstrate for the first time that two of the three L. pneumophila Fis regulators directly repress the expression of Icm/Dot effector-encoding genes. PMID:25225276

  3. Classification of toddler nutritional status using fuzzy inference system (FIS)

    NASA Astrophysics Data System (ADS)

    Permatasari, Dian; Azizah, Isnaini Nur; Hadiat, Hanifah Latifah; Abadi, Agus Maman

    2017-08-01

    Nutrition is a major health problem and concern for parents when it is relating with their toddler. The nutritional status is an expression of the state caused by the status of the balance between the number of intake of nutrients and the amount needed by the body for a variety of biological functions. The indicators that often used to determine the nutritional status is the combination of Weight (W) and Height (H) symbolized by W/H, because it describe a sensitive and specific nutritional status. This study aims to apply the Fuzzy Inference System Mamdani method to classify the nutritional status of toddler. The inputs are weight and height of the toddler. There are nine rules that used and the output is nutritional status classification consisting of four criteria: stunting, wasting, normal, and overweight. Fuzzy Inference System that be used is Mamdani method and the defuzzification use Centroid Method. The result of this study is compared with Assessment Anthropometric Standard of Toddler Nutritional Status by Ministry of Health. The accuracy level of this fuzzy model is about 84%.

  4. Mechanical constraints on Hin subunit rotation imposed by the Fis-enhancer system and DNA supercoiling during site-specific recombination

    PubMed Central

    Dhar, Gautam; Heiss, John K.; Johnson, Reid C.

    2009-01-01

    Summary Hin, a member of the serine family of site-specific recombinases, regulates gene expression by inverting a DNA segment. DNA inversion requires assembly of an invertasome complex in which a recombinational enhancer DNA segment bound by the Fis protein associates with the Hin synaptic complex at the base of a supercoiled DNA branch. Each of the four Hin subunits becomes covalently joined to the cleaved DNA ends, and DNA exchange occurs by translocation of a Hin subunit pair within the tetramer. We show here that although the Hin tetramer forms a bidirectional molecular swivel, the Fis/enhancer system determines both the direction and number of subunit rotations. The chirality of supercoiling directs rotational direction, and the short DNA loop stabilized by Fis-Hin contacts limit rotational processivity, thereby ensuring that the DNA strands re-ligate in the recombinant configuration. We identify multiple rotational conformers that are formed under different supercoiling and solution conditions. PMID:19560425

  5. GeoFIS: An integrated tool for the assessment of landslide susceptibility

    NASA Astrophysics Data System (ADS)

    Osna, Turgay; Sezer, Ebru Akcapinar; Akgun, Aykut

    2014-05-01

    In this study, requirements of landslide susceptibility mapping by a Mamdani fuzzy inference system (FIS) are identified, and a single standalone application (GeoFIS) is developed. GeoFIS includes two main open source libraries, one for GIS operations and the other for creating Mamdani FIS. As a result, it is possible to construct a landslide susceptibility map based on expert opinion, to visualize maps instantly and to measure model performance. GeoFIS supports all steps of the landslide susceptibility mapping process, starting from data deployment and ending with performance measurement. In GeoFIS, visual controls allow use of the inferred results and actual landslide occurrence information, and ROC-AUC values are calculated automatically. Moreover, a confusion matrix is produced, and alternative measurement schemes such as recall are suggested, to reveal those performance details not observable with ROC-AUC and to create trust in the inferred results. GeoFIS is applied to the Trabzon region of northern Turkey, and the recall and ROC-AUC values were .902 and .602, respectively.

  6. FIS/ANFIS Based Optimal Control for Maximum Power Extraction in Variable-speed Wind Energy Conversion System

    NASA Astrophysics Data System (ADS)

    Nadhir, Ahmad; Naba, Agus; Hiyama, Takashi

    An optimal control for maximizing extraction of power in variable-speed wind energy conversion system is presented. Intelligent gradient detection by fuzzy inference system (FIS) in maximum power point tracking control is proposed to achieve power curve operating near optimal point. Speed rotor reference can be adjusted by maximum power point tracking fuzzy controller (MPPTFC) such that the turbine operates around maximum power. Power curve model can be modelled by using adaptive neuro fuzzy inference system (ANFIS). It is required to simply well estimate just a few number of maximum power points corresponding to optimum generator rotor speed under varying wind speed, implying its training can be done with less effort. Using the trained fuzzy model, some estimated maximum power points as well as their corresponding generator rotor speed and wind speed are determined, from which a linear wind speed feedback controller (LWSFC) capable of producing optimum generator speed can be obtained. Applied to a squirrel-cage induction generator based wind energy conversion system, MPPTFC and LWSFC could maximize extraction of the wind energy, verified by a power coefficient stay at its maximum almost all the time and an actual power line close to a maximum power efficiency line reference.

  7. Information Seen as Part of the Development of Living Intelligence: the Five-Leveled Cybersemiotic Framework for FIS

    NASA Astrophysics Data System (ADS)

    Brier, Soren

    2003-06-01

    It is argued that a true transdisciplinary information science going from physical information to phenomenological understanding needs a metaphysical framework. Three different kinds of causality are implied: efficient, formal and final. And at least five different levels of existence are needed: 1. The quantum vacuum fields with entangled causation. 2. The physical level with is energy and force-based efficient causation. 3. The informational-chemical level with its formal causation based on pattern fitting. 4. The biological-semiotic level with its non-conscious final causation and 5. The social-linguistic level of self-consciousness with its conscious goal-oriented final causation. To integrate these consistently in an evolutionary theory as emergent levels, neither mechanical determinism nor complexity theory are sufficient because they cannot be a foundation for a theory of lived meaning. C. S. Peirce's triadic semiotic philosophy combined with a cybernetic and systemic view, like N. Luhmann's, could create the framework I call Cybersemiotics.

  8. The Fluvial Information System

    NASA Astrophysics Data System (ADS)

    Dugdale, S. J.; Carbonneau, P.; Clough, S.

    2009-12-01

    River ecologists have long been aware that our understanding of lotic ecology is limited by our lack of methods applicable to catchment scale processes. Furthermore, the EU’s Water Framework Directive states that surface waters must be managed at catchment scales. This has created a need for a new approach to high-resolution catchment scale data collection in fluvial environments. In response to this, remote sensing has been the focus of increasing interest in river science, and it is now possible to map parameters such as water depth, grain size and habitat type with sub-metric resolutions over large areas. These techniques are capable of yielding unprecedented amounts of information about river systems, and with such levels of information, crucial questions about catchment scale ecology can now be addressed. However, this intensive approach produces vast amounts of raster data leading to significant issues in terms of data management, and extracting spatially explicit information from large image databases poses a significant challenge which must be resolved if fluvial remote sensing methods are to deliver their potential. GIS has already been successfully applied to manage remotely sensed data. Unfortunately, when applied to fluvial remote sensing raster data, traditional GIS appears limited and unsuited to the specific tasks required by river scientists and managers, and experience with GIS packages has shown that they become overwhelmed when faced with datasets comprising thousands of rasters. Another fundamental issue with traditional GIS packages is the use of established Cartesian map projection systems. Given that rivers are curvilinear entities, the use of Cartesian grid map projections is mismatched and curvilinear coordinate systems unique to each river will be required. This paper introduces the Fluvial Information System (FIS), a raster based GIS-type system designed to manage fluvial remote sensing data and automatically extract meaningful

  9. The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction

    SciTech Connect

    Serasinghe, Madhavika N.; Yoon, Yisang

    2008-11-15

    Mitochondrial fission in mammals is mediated by at least two proteins, DLP1/Drp1 and hFis1. DLP1 mediates the scission of mitochondrial membranes through GTP hydrolysis, and hFis1 is a putative DLP1 receptor anchored at the mitochondrial outer membrane by a C-terminal single transmembrane domain. The cytosolic domain of hFis1 contains six {alpha}-helices ({alpha}1-{alpha}6) out of which {alpha}2-{alpha}5 form two tetratricopeptide repeat (TPR) folds. In this study, by using chimeric constructs, we demonstrated that the cytosolic domain contains the necessary information for hFis1 function during mitochondrial fission. By using transient expression of different mutant forms of the hFis1 protein, we found that hFis1 self-interaction plays an important role in mitochondrial fission. Our results show that deletion of the {alpha}1 helix greatly increased the formation of dimeric and oligomeric forms of hFis1, indicating that {alpha}1 helix functions as a negative regulator of the hFis1 self-interaction. Further mutational approaches revealed that a tyrosine residue in the {alpha}5 helix and the linker between {alpha}3 and {alpha}4 helices participate in hFis1 oligomerization. Mutations causing oligomerization defect greatly reduced the ability to induce not only mitochondrial fragmentation by full-length hFis1 but also the formation of swollen ball-shaped mitochondria caused by {alpha}1-deleted hFis1. Our data suggest that oligomerization of hFis1 in the mitochondrial outer membrane plays a role in mitochondrial fission, potentially through participating in fission factor recruitment.

  10. A selection of AKARI FIS BSC extragalactic objects

    NASA Astrophysics Data System (ADS)

    Marton, G.; Tóth, L. V.; Balázs, L. G.; Zahorecz, S.; Bagoly, Z.; Horváth, I.; Rácz, I. I.; Nagy, A.

    The point sources in the Bright Source Catalogue (BSC) of the AKARI Far-Infrared Surveyor (FIS) were classified based on their far-IR and mid-IR fluxes and colours using Quadratic Discriminant Analysis method (QDA) and Support Vector Machines (SVM). The reliability of our results show that we can successfully separate galactic and extragalactic AKARI point sources in the multidimensional space of fluxes and colours. However, differentiating among the extragalactic sub-types needs further information.

  11. Silencing of toxic gene expression by Fis

    PubMed Central

    Karambelkar, Shweta; Swapna, Ganduri; Nagaraja, Valakunja

    2012-01-01

    Bacteria and bacteriophages have evolved DNA modification as a strategy to protect their genomes. Mom protein of bacteriophage Mu modifies the phage DNA, rendering it refractile to numerous restriction enzymes and in turn enabling the phage to successfully invade a variety of hosts. A strong fortification, a combined activity of the phage and host factors, prevents untimely expression of mom and associated toxic effects. Here, we identify the bacterial chromatin architectural protein Fis as an additional player in this crowded regulatory cascade. Both in vivo and in vitro studies described here indicate that Fis acts as a transcriptional repressor of mom promoter. Further, our data shows that Fis mediates its repressive effect by denying access to RNA polymerase at mom promoter. We propose that a combined repressive effect of Fis and previously characterized negative regulatory factors could be responsible to keep the gene silenced most of the time. We thus present a new facet of Fis function in Mu biology. In addition to bringing about overall downregulation of Mu genome, it also ensures silencing of the advantageous but potentially lethal mom gene. PMID:22287621

  12. Data and Visualizations in the Southern California Earthquake Center's Fault Information System

    NASA Astrophysics Data System (ADS)

    Perry, S.

    2003-12-01

    The Southern California Earthquake Center's Fault Information System (FIS) provides a single point of access to fault-related data and models from multiple databases and datasets. The FIS is built of computer code, metadata and Web interfaces based on Web services technology, which enables queries and data interchange irrespective of computer software or platform. Currently we have working prototypes of programmatic and browser-based access. The first generation FIS may be searched and downloaded live, by automated processes, as well as interactively, by humans using a browser. Users get ascii data in plain text or encoded in XML. Via the Earthquake Information Technology (EIT) Interns (Juve and others, this meeting), we are also testing the effectiveness of querying multiple databases using a fault database ontology. For more than a decade, the California Geological Survey (CGS), SCEC, and the U. S. Geological Survey (USGS) have put considerable, shared resources into compiling and assessing published fault data, then providing the data on the Web. Several databases now exist, with different formats, datasets, purposes, and users, in various stages of completion. When fault databases were first envisioned, the full power of today's internet was not yet recognized, and the databases became the Web equivalents of review papers, where one could read an overview summation of a fault, then copy and paste pertinent data. Today, numerous researchers also require rapid queries and downloads of data. Consequently, the first components of the FIS are MySQL databases that deliver numeric values from earlier, text-based databases. Another essential service provided by the FIS is visualizations of fault representations such as those in SCEC's Community Fault Model. The long term goal is to provide a standardized, open-source, platform-independent visualization technique. Currently, the FIS makes available fault model viewing software for users with access to Matlab or Java3D

  13. FIS-dependent trans activation of stable RNA operons of Escherichia coli under various growth conditions.

    PubMed

    Nilsson, L; Verbeek, H; Vijgenboom, E; van Drunen, C; Vanet, A; Bosch, L

    1992-02-01

    In Escherichia coli transcription of the tRNA operon thrU (tufB) and the rRNA operon rrnB is trans-activated by the protein FIS. This protein, which stimulates the inversion of various viral DNA segments, binds specifically to a cis-acting sequence (designated UAS) upstream of the promoter of thrU (tufB) and the P1 promoter of the rrnB operon. There are indications that this type of regulation is representative for the regulation of more stable RNA operons. In the present investigation we have studied UAS-dependent transcription activation of the thrU (tufB) operon in the presence and absence of FIS during a normal bacterial growth cycle and after a nutritional shift-up. In early log phase the expression of the operon rises steeply in wild-type cells, whereafter it declines. Concomitantly, a peak of the cellular FIS concentration is observed. Cells in the stationary phase are depleted of FIS. The rather abrupt increase of transcription activation depends on the nutritional quality of the medium. It is not seen in minimal medium. After a shift from minimal to rich medium, a peak of transcription activation and of FIS concentration is measured. This peak gets higher as the medium gets more strongly enriched. We conclude that a correlation between changes of the UAS-dependent activation of the thrU (tufB) operon and changes of the cellular FIS concentration under a variety of experimental conditions exists. This correlation strongly suggests that the production of FIS responds to environmental signals, thereby trans-activating the operon. Cells unable to produce FIS (fis cells) also show an increase of operon transcription in the early log phase and after a nutritional shift-up, albeit less pronounced than that wild-type cells. Presumably it is controlled by the ribosome feedback regulatory system. cis activation of the operon by the upstream activator sequence is apparent in the absence of FIS. This activation is constant throughout the entire growth cycle and is

  14. Weather Information Communications (WINCOMM) Overview and Status

    NASA Technical Reports Server (NTRS)

    Martzaklis, K.

    2003-01-01

    The second annual project review of Weather Information Communications (WINCOMM) is presented. The topics of discussion include: 1) In-Flight Weather Information; 2) System Elements; 3) Technology Investment Areas; 4) NAS Information Exchange; 5) FIS Datalink Architecture Analyses; 6) Hybrid FIS Datalink Architecture; 7) FIS Datalink Architecture Analyses; 8) Air Transport: Ground and Satellite-based Datalinks; 9) General Aviation: Ground and Satellite-based Datalinks; 10) Low Altitude AutoMET Reporting; 11) AutoMET: Airborne-based Datalinks; 12) Network Protocols Development; and 13) FAA/NASA Collaboration. A summary of WINCOMM is also included. This paper is in viewgraph form.

  15. The Haemophilus ducreyi Fis protein is involved in controlling expression of the lspB-lspA2 operon and other virulence factors.

    PubMed

    Labandeira-Rey, Maria; Dodd, Dana A; Brautigam, Chad A; Fortney, Kate R; Spinola, Stanley M; Hansen, Eric J

    2013-11-01

    Expression of the lspB-lspA2 operon encoding a virulence-related two-partner secretion system in Haemophilus ducreyi 35000HP is directly regulated by the CpxRA regulatory system (M. Labandeira-Rey, J. R. Mock, and E. J. Hansen, Infect. Immun. 77:3402-3411, 2009). In the present study, we show that this secretion system is also regulated by the small nucleoid-associated protein Fis. Inactivation of the H. ducreyi fis gene resulted in a reduction in expression of both the H. ducreyi LspB and LspA2 proteins. DNA microarray experiments showed that a H. ducreyi fis deletion mutant exhibited altered expression levels of genes encoding other important H. ducreyi virulence factors, including DsrA and Flp1, suggesting a possible global role for Fis in the control of virulence in this obligate human pathogen. While the H. ducreyi Fis protein has a high degree of sequence and structural similarity to the Fis proteins of other bacteria, its temporal pattern of expression was very different from that of enterobacterial Fis proteins. The use of a lacZ-based transcriptional reporter provided evidence which indicated that the H. ducreyi Fis homolog is a positive regulator of gyrB, a gene that is negatively regulated by Fis in enteric bacteria. Taken together, the Fis protein expression data and the observed regulatory effects of Fis in H. ducreyi suggest that this small DNA binding protein has a regulatory role in H. ducreyi which may differ in substantial ways from that of other Fis proteins.

  16. Expression and parent-of-origin effects for FIS2, MEA, and FIE in the endosperm and embryo of developing Arabidopsis seeds.

    PubMed

    Luo, M; Bilodeau, P; Dennis, E S; Peacock, W J; Chaudhury, A

    2000-09-12

    The promoters of MEA (FIS1), FIS2, and FIE (FIS3), genes that repress seed development in the absence of pollination, were fused to beta-glucuronidase (GUS) to study their activity pattern. The FIS2GUS product is found in the embryo sac, in each of the polar cell nuclei, and in the central cell nucleus. After pollination, the maternally derived FIS2GUS protein occurs in the nuclei of the cenocytic endosperm. Before cellularization of the endosperm, activity is terminated in the micropylar and central nuclei of the endosperm and subsequently in the nuclei of the chalazal cyst. MEAGUS has a pattern of activity similar to that of FIS2GUS, but FIEGUS protein is found in many tissues, including the prepollination embryo sac, and in embryo and endosperm postpollination. The similarity in mutant phenotypes; the activity of FIE, MEA, and FIS2 in the same cells in the embryo sac; and the fact that MEA and FIE proteins interact in a yeast two-hybrid system suggest that these proteins operate in the same system of control of seed development. Maternal and not paternal FIS2GUS, MEAGUS, and FIEGUS show activity in early endosperm, so these genes may be imprinted. When fis2, mea, and fie mutants are pollinated, seed development is arrested at the heart embryo stage. The seed arrest of mea and fis2 is avoided when they are fertilized by a low methylation parent. The wild-type alleles of MEA or FIS2 are not required. The parent-of-origin-determined differential activity of MEA, FIS2, and FIE is not dependent on DNA methylation, but methylation does control some gene(s) that have key roles in seed development.

  17. Identification and Characterization of the fis Operon in Enteric Bacteria

    PubMed Central

    Beach, Michael B.; Osuna, Robert

    1998-01-01

    The small DNA binding protein Fis is involved in several different biological processes in Escherichia coli. It has been shown to stimulate DNA inversion reactions mediated by the Hin family of recombinases, stimulate integration and excision of phage λ genome, regulate the transcription of several different genes including those of stable RNA operons, and regulate the initiation of DNA replication at oriC. fis has also been isolated from Salmonella typhimurium, and the genomic sequence of Haemophilus influenzae reveals its presence in this bacteria. This work extends the characterization of fis to other organisms. Very similar fis operon structures were identified in the enteric bacteria Klebsiella pneumoniae, Serratia marcescens, Erwinia carotovora, and Proteus vulgaris but not in several nonenteric bacteria. We found that the deduced amino acid sequences for Fis are 100% identical in K. pneumoniae, S. marcescens, E. coli, and S. typhimurium and 96 to 98% identical when E. carotovora and P. vulgaris Fis are considered. The deduced amino acid sequence for H. influenzae Fis is about 80% identical and 90% similar to Fis in enteric bacteria. However, in spite of these similarities, the E. carotovora, P. vulgaris, and H. influenzae Fis proteins are not functionally identical. An open reading frame (ORF1) preceding fis in E. coli is also found in all these bacteria, and their deduced amino acid sequences are also very similar. The sequence preceding ORF1 in the enteric bacteria showed a very strong similarity to the E. coli fis P region from −53 to +27 and the region around −116 containing an ihf binding site. Both β-galactosidase assays and primer extension assays showed that these regions function as promoters in vivo and are subject to growth phase-dependent regulation. However, their promoter strengths vary, as do their responses to Fis autoregulation and integration host factor stimulation. PMID:9811652

  18. Identification and characterization of the fis operon in enteric bacteria.

    PubMed

    Beach, M B; Osuna, R

    1998-11-01

    The small DNA binding protein Fis is involved in several different biological processes in Escherichia coli. It has been shown to stimulate DNA inversion reactions mediated by the Hin family of recombinases, stimulate integration and excision of phage lambda genome, regulate the transcription of several different genes including those of stable RNA operons, and regulate the initiation of DNA replication at oriC. fis has also been isolated from Salmonella typhimurium, and the genomic sequence of Haemophilus influenzae reveals its presence in this bacteria. This work extends the characterization of fis to other organisms. Very similar fis operon structures were identified in the enteric bacteria Klebsiella pneumoniae, Serratia marcescens, Erwinia carotovora, and Proteus vulgaris but not in several nonenteric bacteria. We found that the deduced amino acid sequences for Fis are 100% identical in K. pneumoniae, S. marcescens, E. coli, and S. typhimurium and 96 to 98% identical when E. carotovora and P. vulgaris Fis are considered. The deduced amino acid sequence for H. influenzae Fis is about 80% identical and 90% similar to Fis in enteric bacteria. However, in spite of these similarities, the E. carotovora, P. vulgaris, and H. influenzae Fis proteins are not functionally identical. An open reading frame (ORF1) preceding fis in E. coli is also found in all these bacteria, and their deduced amino acid sequences are also very similar. The sequence preceding ORF1 in the enteric bacteria showed a very strong similarity to the E. coli fis P region from -53 to +27 and the region around -116 containing an ihf binding site. Both beta-galactosidase assays and primer extension assays showed that these regions function as promoters in vivo and are subject to growth phase-dependent regulation. However, their promoter strengths vary, as do their responses to Fis autoregulation and integration host factor stimulation.

  19. Proposals for the Future Development of the Russian Automated Federal Information System for Nuclear Material Control and Accounting: The Universal Reporting Concept

    SciTech Connect

    Martiyanov, A; Pitel, V; Kasumova, L; Babcock, R; Heinberg, C

    2004-06-17

    Development of the automated Russian Federation Federal Information System for Nuclear Material Control and Accounting (FIS) started in 1996. From the beginning, the creation of the FIS was based on the concept of obtaining data from the material balance areas of the organizations, which would enable the system to collect detailed information on nuclear material. In December 2000, the organization-level summarized reporting method was mandated by the Russian Federation and subsequently implemented for all organizations. Analysis of long-term FIS objectives, reporting by all the MBAs in Russia, showed that the present summarized reporting approach decreed by regulations posed a fair number of problems. We need alternative methods that allow the FIS to obtain more detailed information on nuclear material but which accurately reflect the technical and economic resources available to Russian organizations. One possible solution is the universal reporting method. In August 2003, the proposals of the FIS working group to transition to the universal reporting method were approved at the fourth meeting of the Joint Coordinating Committee for Implementation of the Russian Federation and U.S. Government-to-Government Agreement on Cooperation in the Area of Nuclear Material Physical Protection, Control and Accounting (JCC). One of the important elements of universal reporting is that organizations handling nuclear material will establish 'reporting areas' in cooperation with MinAtom of Russia. A reporting area may consist of one MBA, several MBAs, or even an entire organization. This paper will discuss the universal reporting concept and its major objectives and methods for the FIS.

  20. The E.coli fis promoter is subject to stringent control and autoregulation.

    PubMed Central

    Ninnemann, O; Koch, C; Kahmann, R

    1992-01-01

    The DNA binding protein FIS is involved in processes like site specific DNA inversion, lambda excision and stimulation of stable RNA synthesis in Escherichia coli. The amount of FIS protein is subject to dramatic changes during growth. We demonstrate that fis is part of an operon with one ORF of unknown function preceding the fis gene. Regulation of fis synthesis occurs at the transcriptional level. Within 15 min after nutritional upshift a large burst of fis mRNA is produced which levels off when cells begin to grow. By mutational analysis using promoter-lacZ fusions we demonstrate that the fis promoter is autoregulated by FIS. Growth phase regulation of the fis promoter depends on the presence of a GC motif downstream of the -10 region. We show that the fis promoter is subject to stringent control and discuss this unusual feature with respect to the known and putative functions FIS serves in E. coli. Images PMID:1547773

  1. Data Systems vs. Information Systems

    PubMed Central

    Amatayakul, Margret K.

    1982-01-01

    This paper examines the current status of “hospital information systems” with respect to the distinction between data systems and information systems. It is proposed that the systems currently existing are incomplete data dystems resulting in ineffective information systems.

  2. Quantify information system benefits

    SciTech Connect

    Koppel, L.B.

    1995-06-01

    What are information systems and how do they relate to control systems? How do information systems produce benefits in hydrocarbon processing? What are some examples of benefit-generating information system applications? Information System Benefits (ISBEN) is a structured methodology for estimating information system benefits in hydrocarbon processing. The paper discusses information and control systems, information system benefits and applications, objectives, strategies and measures of ISBEN, ISBEN business drivers, ISBEN database, ISBEN methodology, and implementation.

  3. FIS -- Far-Infrared Surveyor onboard the ASTRO-F

    NASA Astrophysics Data System (ADS)

    Kawada, M.

    2000-12-01

    The Far-Infrared Surveyor (FIS) is one of the two focal plane instruments of ASTRO-F which is a Japanese infrared astronomical satellite planned to launch in early 2004. The FIS is designed primarily to perform an all-sky survey in 4 photometric bands at wavelength of 50 - 200 micron. The sensitivity of the FIS is several ten times higher than IRAS (Infrared Astronomical Satellite) because of the improvement on the detector performance based on the recent device technology. The FIS is expected to provide a new generation all-sky catalog of infrared sources, which could become a standard database in many fields of astrophysics. The FIS also has spectroscopic capability which is realized by a Fourier transform spectrometer. The spectrometer covers 50 - 200 cm-1 in wavenumber with 0.2 cm-1 spectral resolution. The spectrometer is quite a powerful tool to reveal the physical properties of the objects such as new objects detected by the all-sky survey or known interesting sources.

  4. Fis Is Essential for Yersinia pseudotuberculosis Virulence and Protects against Reactive Oxygen Species Produced by Phagocytic Cells during Infection

    PubMed Central

    Green, Erin R.; Clark, Stacie; Crimmins, Gregory T.; Mack, Matthias; Kumamoto, Carol A.; Mecsas, Joan

    2016-01-01

    All three pathogenic Yersinia species share a conserved virulence plasmid that encodes a Type 3 Secretion System (T3SS) and its associated effector proteins. During mammalian infection, these effectors are injected into innate immune cells, where they block many bactericidal functions, including the production of reactive oxygen species (ROS). However, Y. pseudotuberculosis (Yptb) lacking the T3SS retains the ability to colonize host organs, demonstrating that chromosome-encoded factors are sufficient for growth within mammalian tissue sites. Previously we uncovered more than 30 chromosomal factors that contribute to growth of T3SS-deficient Yptb in livers. Here, a deep sequencing-based approach was used to validate and characterize the phenotype of 18 of these genes during infection by both WT and plasmid-deficient Yptb. Additionally, the fitness of these mutants was evaluated in immunocompromised mice to determine whether any genes contributed to defense against phagocytic cell restriction. Mutants containing deletions of the dusB-fis operon, which encodes the nucleoid associated protein Fis, were markedly attenuated in immunocompetent mice, but were restored for growth in mice lacking neutrophils and inflammatory monocytes, two of the major cell types responsible for restricting Yersinia infection. We determined that Fis was dispensable for secretion of T3SS effectors, but was essential for resisting ROS and regulated the transcription of several ROS-responsive genes. Strikingly, this protection was critical for virulence, as growth of ΔdusB-fis was restored in mice unable to produce ROS. These data support a model in which ROS generated by neutrophils and inflammatory monocytes that have not been translocated with T3SS effectors enter bacterial cells during infection, where their bactericidal effects are resisted in a Fis-dependent manner. This is the first report of the requirement for Fis during Yersinia infection and also highlights a novel mechanism by

  5. Mission Medical Information System

    NASA Technical Reports Server (NTRS)

    Johnson-Throop, Kathy A.; Joe, John C.; Follansbee, Nicole M.

    2008-01-01

    This viewgraph presentation gives an overview of the Mission Medical Information System (MMIS). The topics include: 1) What is MMIS?; 2) MMIS Goals; 3) Terrestrial Health Information Technology Vision; 4) NASA Health Information Technology Needs; 5) Mission Medical Information System Components; 6) Electronic Medical Record; 7) Longitudinal Study of Astronaut Health (LSAH); 8) Methods; and 9) Data Submission Agreement (example).

  6. Dramatic changes in Fis levels upon nutrient upshift in Escherichia coli.

    PubMed Central

    Ball, C A; Osuna, R; Ferguson, K C; Johnson, R C

    1992-01-01

    Fis is a small basic DNA-binding protein from Escherichia coli that was identified because of its role in site-specific DNA recombination reactions. Recent evidence indicates that Fis also participates in essential cell processes such as rRNA and tRNA transcription and chromosomal DNA replication. In this report, we show that Fis levels vary dramatically during the course of cell growth and in response to changing environmental conditions. When stationary-phase cells are subcultured into a rich medium, Fis levels increase from less than 100 to over 50,000 copies per cell prior to the first cell division. As cells enter exponential growth, nascent synthesis is largely shut off, and intracellular Fis levels decrease as a function of cell division. Fis synthesis also transiently increases when exponentially growing cells are shifted to a richer medium. The magnitude of the peak of Fis synthesis appears to reflect the extent of the nutritional upshift. fis mRNA levels closely resemble the protein expression pattern, suggesting that regulation occurs largely at the transcriptional level. Two RNA polymerase-binding sites and at least six high-affinity Fis-binding sites are present in the fis promoter region. We show that expression of the fis operon is negatively regulated by Fis in vivo and that purified Fis can prevent stable complex formation by RNA polymerase at the fis promoter in vitro. However, autoregulation only partially accounts for the expression pattern of Fis. We suggest that the fluctuations in Fis levels may serve as an early signal of a nutritional upshift and may be important in the physiological roles Fis plays in the cell. Images PMID:1459953

  7. MILITARY INFORMATION SYSTEMS,

    DTIC Science & Technology

    upward are usually indications of how effectively the system is developing or operating. The use of computers in information systems tends to increase...computers into information systems must always begin at the lowest level of aggregation in the job hierarchy. Only those information-processing jobs

  8. Mobile Student Information System

    ERIC Educational Resources Information Center

    Asif, Muhammad; Krogstie, John

    2011-01-01

    Purpose: A mobile student information system (MSIS) based on mobile computing and context-aware application concepts can provide more user-centric information services to students. The purpose of this paper is to describe a system for providing relevant information to students on a mobile platform. Design/methodology/approach: The research…

  9. Community Information Systems.

    ERIC Educational Resources Information Center

    Freeman, Andrew

    Information is provided on technological and social trends as background for a workshop designed to heighten the consciousness of workers in community information systems. Initially, the basic terminology is considered in its implications for an integrated perspective of community information systems, with particular attention given to the meaning…

  10. Strategic Information Systems Planning.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    1995-01-01

    Strategic Information Systems Planning (SISP) is the process of establishing a program for implementation and use of information systems in ways that will optimize effectiveness of information resources and use them to support the objectives of the organization. Basic steps in SISP methodology are outlined. (JKP)

  11. Mobile Student Information System

    ERIC Educational Resources Information Center

    Asif, Muhammad; Krogstie, John

    2011-01-01

    Purpose: A mobile student information system (MSIS) based on mobile computing and context-aware application concepts can provide more user-centric information services to students. The purpose of this paper is to describe a system for providing relevant information to students on a mobile platform. Design/methodology/approach: The research…

  12. Information extraction system

    DOEpatents

    Lemmond, Tracy D; Hanley, William G; Guensche, Joseph Wendell; Perry, Nathan C; Nitao, John J; Kidwell, Paul Brandon; Boakye, Kofi Agyeman; Glaser, Ron E; Prenger, Ryan James

    2014-05-13

    An information extraction system and methods of operating the system are provided. In particular, an information extraction system for performing meta-extraction of named entities of people, organizations, and locations as well as relationships and events from text documents are described herein.

  13. Regional Health Information Systems

    PubMed Central

    Fuller, Sherrilynne

    1997-01-01

    Abstract In general, there is agreement that robust integrated information systems are the foundation for building successful regional health care delivery systems. Integrated Advanced Information Management System (IAIMS) institutions that, over the years, have developed strategies for creating cohesive institutional information systems and services are finding that IAIMS strategies work well in the even more complex regional environment. The key elements of IAIMS planning are described and lessons learned are discussed in the context of regional health information systems developed. The challenges of aligning the various information agencies and agendas in support of a regional health information system are complex ; however, the potential rewards for health care in quality, efficacy, and cost savings are enormous. PMID:9067887

  14. ECONOMICS OF INFORMATION SYSTEMS

    DTIC Science & Technology

    The paper presents a study of the rational choice-making of an individual from among available information systems , or available components of such...components, of information systems . The available set depends on the choices made by suppliers. Joint choices by demanders and suppliers would...determine which information systems are in fact produced and used under given external conditions. These conditions include the technological knowledge of those concerned.

  15. Management Information Systems Research.

    DTIC Science & Technology

    Research on management information systems is illusive in many respects. Part of the basic research problem in MIS stems from the absence of standard...definitions and the lack of a unified body of theory. Organizations continue to develop large and often very efficient information systems , but...decision making. But the transition from these results to the realization of ’satisfactory’ management information systems remains difficult indeed. The

  16. Weather Information System

    NASA Technical Reports Server (NTRS)

    1995-01-01

    WxLink is an aviation weather system based on advanced airborne sensors, precise positioning available from the satellite-based Global Positioning System, cockpit graphics and a low-cost datalink. It is a two-way system that uplinks weather information to the aircraft and downlinks automatic pilot reports of weather conditions aloft. Manufactured by ARNAV Systems, Inc., the original technology came from Langley Research Center's cockpit weather information system, CWIN (Cockpit Weather INformation). The system creates radar maps of storms, lightning and reports of surface observations, offering improved safety, better weather monitoring and substantial fuel savings.

  17. Information retrieval system

    NASA Technical Reports Server (NTRS)

    Berg, R. F.; Holcomb, J. E.; Kelroy, E. A.; Levine, D. A.; Mee, C., III

    1970-01-01

    Generalized information storage and retrieval system capable of generating and maintaining a file, gathering statistics, sorting output, and generating final reports for output is reviewed. File generation and file maintenance programs written for the system are general purpose routines.

  18. Medical Information Management System

    NASA Technical Reports Server (NTRS)

    Alterescu, S.; Hipkins, K. R.; Friedman, C. A.

    1979-01-01

    On-line interactive information processing system easily and rapidly handles all aspects of data management related to patient care. General purpose system is flexible enough to be applied to other data management situations found in areas such as occupational safety data, judicial information, or personnel records.

  19. Anesthesia information management systems.

    PubMed

    Williams, Joe R

    2005-06-01

    Documentation is the last component of anesthesia patient management to be affected by technology. Anesthesia information management systems (AIMS) have been introduced in a limited number of practice sites. The automated systems provide unbiased reporting of most patient information. This results in improved patient care and possible medical legal advantages. AIMS also allow anesthesia departments to monitor their business related activity.

  20. Environmental geographic information system.

    SciTech Connect

    Peek, Dennis W; Helfrich, Donald Alan; Gorman, Susan

    2010-08-01

    This document describes how the Environmental Geographic Information System (EGIS) was used, along with externally received data, to create maps for the Site-Wide Environmental Impact Statement (SWEIS) Source Document project. Data quality among the various classes of geographic information system (GIS) data is addressed. A complete listing of map layers used is provided.

  1. Information Retrieval System.

    ERIC Educational Resources Information Center

    Mahle, Jack D., Jr.

    The Fort Detrick Information Retrieval System is a system of computer programs written in COBOL for a CDC 3150 to store and retrieve information about the scientific and technical reports and documents of the Fort Detrick Technical Library. The documents and reports have been abstracted and indexed. This abstract, the subject matter descriptors,…

  2. Archival Information Management System.

    DTIC Science & Technology

    1995-02-01

    management system named Archival Information Management System (AIMS), designed to meet the audit trail requirement for studies completed under the...are to be archived to the extent that future reproducibility and interrogation of results will exist. This report presents a prototype information

  3. Structural Basis for Recruitment of Mitochondrial Fission Complexes By Fis1

    SciTech Connect

    Zhang, Y.; Chan, D.C.

    2009-06-04

    Mitochondrial fission controls mitochondrial shape and physiology, including mitochondrial remodeling in apoptosis. During assembly of the yeast mitochondrial fission complex, the outer membrane protein Fis1 recruits the dynamin-related GTPase Dnm1 to mitochondria. Fis1 contains a tetratricopeptide repeat (TPR) domain and interacts with Dnm1 via the molecular adaptors Mdv1 and Caf4. By using crystallographic analysis of adaptor-Fis1 complexes, we show that these adaptors use two helices to bind to both the concave and convex surfaces of the Fis1 TPR domain. Fis1 therefore contains two interaction interfaces, a binding mode that, to our knowledge, has not been observed previously for TPR domains. Genetic and biochemical studies indicate that both binding interfaces are important for binding of Mdv1 and Caf4 to Fis1 and for mitochondrial fission activity in vivo. Our results reveal how Fis1 recruits the mitochondrial fission complex and will facilitate efforts to manipulate mitochondrial fission.

  4. Ensuring the Sustainability of Russian Federation National Nuclear Material Accounting System

    SciTech Connect

    Pitel, V; Kasumova, L; Kushnaryov, M; Babcock, R

    2006-06-07

    The Federal Nuclear Material Control and Accounting Information System (FIS) is the national information source on nuclear material accounting of the Russian Federation (RF). RF regulations mandated the creation of a national nuclear material accounting system to be managed by Federal Agency For Atomic Energy (Rosatom), and for the past decade, the FIS has been developed for all organizations required to report to Rosatom. The system represents a successful integration of U.S. financial support and consulting with Russian vision and technical expertise, creating a viable national nuclear material accounting system. This paper discusses crucial elements to ensure Sustainability of the FIS. A long-term plan for operation and maintenance of the information system is critical to a sustainable national accounting system. Plans undertaken throughout the FIS Project lifecycle have supported the necessary elements to ensure success. Through the next two years, long-term planning will be reevaluated and the successful elements and new initiatives will become part of an overall Operations Management Program. FIS resource needs will be managed through prioritization and ranking for each Program element, including: system operation; revising and implementing supporting regulations; establishing monitoring and control mechanisms to ensure validity of the data reported; maintaining and improving communication channels; and establishing regular FIS training. The results of a survey on improving FIS reporting, expected in June 2006, will be used in the prioritization and ranking process. Developing the Program and planning for long-term sustainability of the FIS will ensure a viable national nuclear material accounting system for the future.

  5. Next generation information systems

    SciTech Connect

    Limback, Nathan P; Medina, Melanie A; Silva, Michelle E

    2010-01-01

    The Information Systems Analysis and Development (ISAD) Team of the Safeguards Systems Group at Los Alamos National Laboratory (LANL) has been developing web based information and knowledge management systems for sixteen years. Our vision is to rapidly and cost effectively provide knowledge management solutions in the form of interactive information systems that help customers organize, archive, post and retrieve nonproliferation and safeguards knowledge and information vital to their success. The team has developed several comprehensive information systems that assist users in the betterment and growth of their organizations and programs. Through our information systems, users are able to streamline operations, increase productivity, and share and access information from diverse geographic locations. The ISAD team is also producing interactive visual models. Interactive visual models provide many benefits to customers beyond the scope of traditional full-scale modeling. We have the ability to simulate a vision that a customer may propose, without the time constraints of traditional engineering modeling tools. Our interactive visual models can be used to access specialized training areas, controlled areas, and highly radioactive areas, as well as review site-specific training for complex facilities, and asset management. Like the information systems that the ISAD team develops, these models can be shared and accessed from any location with access to the internet. The purpose of this paper is to elaborate on the capabilities of information systems and interactive visual models as well as consider the possibility of combining the two capabilities to provide the next generation of infonnation systems. The collection, processing, and integration of data in new ways can contribute to the security of the nation by providing indicators and information for timely action to decrease the traditional and new nuclear threats. Modeling and simulation tied to comprehensive

  6. A Microbiology Information System

    PubMed Central

    Peebles, James E.; Ryan, Kenneth J.

    1980-01-01

    This paper describes a microbiology information system which is integrated into a general purpose laboratory information system as well as into the normal workflow of the microbiology laboratory. Data entry using “customized” terminal keyboards greatly simplify technologists interaction with the system allowing direct entry of results at each workstation. Results are reported in a user oriented format utilizing full English description of all terms.

  7. Health Information Systems.

    PubMed

    Sirintrapun, S Joseph; Artz, David R

    2015-06-01

    This article provides surgical pathologists an overview of health information systems (HISs): what they are, what they do, and how such systems relate to the practice of surgical pathology. Much of this article is dedicated to the electronic medical record. Information, in how it is captured, transmitted, and conveyed, drives the effectiveness of such electronic medical record functionalities. So critical is information from pathology in integrated clinical care that surgical pathologists are becoming gatekeepers of not only tissue but also information. Better understanding of HISs can empower surgical pathologists to become stakeholders who have an impact on the future direction of quality integrated clinical care.

  8. Health Information Systems.

    PubMed

    Sirintrapun, S Joseph; Artz, David R

    2016-03-01

    This article provides surgical pathologists an overview of health information systems (HISs): what they are, what they do, and how such systems relate to the practice of surgical pathology. Much of this article is dedicated to the electronic medical record. Information, in how it is captured, transmitted, and conveyed, drives the effectiveness of such electronic medical record functionalities. So critical is information from pathology in integrated clinical care that surgical pathologists are becoming gatekeepers of not only tissue but also information. Better understanding of HISs can empower surgical pathologists to become stakeholders who have an impact on the future direction of quality integrated clinical care.

  9. Earthquake Information System

    NASA Astrophysics Data System (ADS)

    1991-01-01

    IAEMIS (Integrated Automated Emergency Management Information System) is the principal tool of an earthquake preparedness program developed by Martin Marietta and the Mid-America Remote Sensing Center (MARC). It is a two-component set of software, data and procedures to provide information enabling management personnel to make informed decisions in disaster situations. The NASA-developed program ELAS, originally used to analyze Landsat data, provides MARC with a spatially-oriented information management system. Additional MARC projects include land resources management, and development of socioeconomic data.

  10. Information of Open Systems

    NASA Astrophysics Data System (ADS)

    Klimontovich, Yuri L.

    In the theory of communication two definitions of the concept "information" are known. One of them coincides according to its form with the Boltzmann entropy. The second definition of information is the difference between unconditional and conditional entropies. In the present work this latter is used for the definition of the information about states of open systems with various meanings of the control parameter. Two kinds of open systems are considered. The first class of systems concerns those which with zero value of the control parameter are in an equilibrium state. The information on an equilibrium state is equal to zero. During self- organizing in the process of departing from an equilibrium state the information increases. For open systems of this class the conservation law for the sum of the information and entropy with all values of control parameter is proved. In open systems of the second class the equilibrium condition is impossible. For them the concept "norm of a chaoticity" is introduced. It allows to consider two kinds of processes of self-organization and to give the corresponding definitions of information. The statement is carried out on a number of (classical and quantum) examples of physical systems. The example of a medico-biological system also is considered.

  11. Air System Information Management

    NASA Technical Reports Server (NTRS)

    Filman, Robert E.

    2004-01-01

    I flew to Washington last week, a trip rich in distributed information management. Buying tickets, at the gate, in flight, landing and at the baggage claim, myriad messages about my reservation, the weather, our flight plans, gates, bags and so forth flew among a variety of travel agency, airline and Federal Aviation Administration (FAA) computers and personnel. By and large, each kind of information ran on a particular application, often specialized to own data formats and communications network. I went to Washington to attend an FAA meeting on System-Wide Information Management (SWIM) for the National Airspace System (NAS) (http://www.nasarchitecture.faa.gov/Tutorials/NAS101.cfm). NAS (and its information infrastructure, SWIM) is an attempt to bring greater regularity, efficiency and uniformity to the collection of stovepipe applications now used to manage air traffic. Current systems hold information about flight plans, flight trajectories, weather, air turbulence, current and forecast weather, radar summaries, hazardous condition warnings, airport and airspace capacity constraints, temporary flight restrictions, and so forth. Information moving among these stovepipe systems is usually mediated by people (for example, air traffic controllers) or single-purpose applications. People, whose intelligence is critical for difficult tasks and unusual circumstances, are not as efficient as computers for tasks that can be automated. Better information sharing can lead to higher system capacity, more efficient utilization and safer operations. Better information sharing through greater automation is possible though not necessarily easy.

  12. Air System Information Management

    NASA Technical Reports Server (NTRS)

    Filman, Robert E.

    2004-01-01

    I flew to Washington last week, a trip rich in distributed information management. Buying tickets, at the gate, in flight, landing and at the baggage claim, myriad messages about my reservation, the weather, our flight plans, gates, bags and so forth flew among a variety of travel agency, airline and Federal Aviation Administration (FAA) computers and personnel. By and large, each kind of information ran on a particular application, often specialized to own data formats and communications network. I went to Washington to attend an FAA meeting on System-Wide Information Management (SWIM) for the National Airspace System (NAS) (http://www.nasarchitecture.faa.gov/Tutorials/NAS101.cfm). NAS (and its information infrastructure, SWIM) is an attempt to bring greater regularity, efficiency and uniformity to the collection of stovepipe applications now used to manage air traffic. Current systems hold information about flight plans, flight trajectories, weather, air turbulence, current and forecast weather, radar summaries, hazardous condition warnings, airport and airspace capacity constraints, temporary flight restrictions, and so forth. Information moving among these stovepipe systems is usually mediated by people (for example, air traffic controllers) or single-purpose applications. People, whose intelligence is critical for difficult tasks and unusual circumstances, are not as efficient as computers for tasks that can be automated. Better information sharing can lead to higher system capacity, more efficient utilization and safer operations. Better information sharing through greater automation is possible though not necessarily easy.

  13. Arkansas Technology Information System.

    ERIC Educational Resources Information Center

    VanBiervliet, Alan; Parette, Howard P., Jr.

    The Arkansas Technology Information System (ARTIS) was developed to fill a significant void in existing systems of technical support to Arkansans with disabilities by creating and maintaining a consumer-responsive statewide system of data storage and retrieval regarding assistive technology and services. ARTIS goals also include establishment of a…

  14. Organizing Information Systems.

    ERIC Educational Resources Information Center

    Thomas, Charles R.

    The development of information systems is described with regard to the roles of the system user and the data processing specialist. Institutional needs are best served by coordination efforts, usually handled by a management systems office, which is also responsible for the maintenance and production of an institutional data element dictionary and…

  15. Information System Overview.

    ERIC Educational Resources Information Center

    Burrows, J. H.

    This paper was prepared for distribution to the California Educational Administrators participating in the "Executive Information Systems" Unit of Instruction as part of the instructional program of Operation PEP (Prepare Educational Planners). The purpose of the course was to introduce some basic concepts of information systems…

  16. Information systems definition architecture

    SciTech Connect

    Calapristi, A.J.

    1996-06-20

    The Tank Waste Remediation System (TWRS) Information Systems Definition architecture evaluated information Management (IM) processes in several key organizations. The intent of the study is to identify improvements in TWRS IM processes that will enable better support to the TWRS mission, and accommodate changes in TWRS business environment. The ultimate goals of the study are to reduce IM costs, Manage the configuration of TWRS IM elements, and improve IM-related process performance.

  17. HS3 Information System

    NASA Astrophysics Data System (ADS)

    Maskey, M.; Conover, H.; Ramachandran, R.; Kulkarni, A.; Mceniry, M.; Stone, B.

    2015-12-01

    The Global Hydrology Resource Center (GHRC) is developing an enterprise information system to manage and better serve data for Hurricane and Severe Storm Sentinel (HS3), a NASA airborne field campaign. HS3 is a multiyear campaign aimed at helping scientists understand the physical processes that contribute to hurricane intensification. For in-depth analysis, HS3 encompasses not only airborne data but also variety of in-situ, satellite, simulation, and flight report data. Thus, HS3 provides a unique challenge in information system design. The GHRC team is experienced with previous airborne campaigns to handle such challenge. Many supplementary information and reports collected during the mission include information rich contents that provide mission snapshots. In particular, flight information, instrument status, weather reports, and summary statistics offer vital knowledge about the corresponding science data. Furthermore, such information help narrow the science data of interest. Therefore, the GHRC team is building HS3 information system that augments the current GHRC data management framework to support search and discover of airborne science data with interactive visual exploration. Specifically, the HS3 information system is developing a tool to visually playback mission flights along with other traditional search and discover interfaces. This playback capability allows the users to follow the flight in time and visualize collected data. The flight summary and analyzed information are also presented during the playback. If the observed data is of interest, then they can order the data from GHRC using the interface. The users will be able to order just the data for the part of the flight that they are interested in. This presentation will demonstrate use of visual exploration to data download along with other components that comprise the HS3 information system.

  18. Dynamic Transcriptional Regulation of Fis in Salmonella During the Exponential Phase.

    PubMed

    Wang, Hui; Wang, Lei; Li, Ping; Hu, Yilang; Zhang, Wei; Tang, Bo

    2015-12-01

    Fis is one of the most important global regulators and has attracted extensive research attention. Many studies have focused on comparing the Fis global regulatory networks for exploring Fis function during different growth stages, such as the exponential and stationary stages. Although the Fis protein in bacteria is mainly expressed in the exponential phase, the dynamic transcriptional regulation of Fis during the exponential phase remains poorly understood. To address this question, we used RNA-seq technology to identify the Fis-regulated genes in the S. enterica serovar Typhimurium during the early exponential phase, and qRT-PCR was performed to validate the transcriptional data. A total of 1495 Fis-regulated genes were successfully identified, including 987 Fis-repressed genes and 508 Fis-activated genes. Comparing the results of this study with those of our previous study, we found that the transcriptional regulation of Fis was diverse during the early- and mid-exponential phases. The results also showed that the strong positive regulation of Fis on Salmonella pathogenicity island genes in the mid-exponential phase transitioned into insignificant effect in the early exponential phase. To validate these results, we performed a cell infection assay and found that Δfis only exhibited a 1.49-fold decreased capacity compared with the LT2 wild-type strain, indicating a large difference from the 6.31-fold decrease observed in the mid-exponential phase. Our results provide strong evidence for a need to thoroughly understand the dynamic transcriptional regulation of Fis in Salmonella during the exponential phase.

  19. Management Information System Project.

    ERIC Educational Resources Information Center

    Foley, Walter J.; Harr, Gordon G.

    The Management Information System (MIS) described in this report represents a plan to utilize modern management techniques to facilitate the goal of a learner-responsive school system. The MIS component is being developed to meet the need for the coordination of the resources of staff, facilities, and time with the long range planning and…

  20. Intelligent Information Systems.

    ERIC Educational Resources Information Center

    Zabezhailo, M. I.; Finn, V. K.

    1996-01-01

    An Intelligent Information System (IIS) uses data warehouse technology to facilitate the cycle of data and knowledge processing, including input, standardization, storage, representation, retrieval, calculation, and delivery. This article provides an overview of IIS products and artificial intelligence systems, illustrates examples of IIS…

  1. NEEDS - Information Adaptive System

    NASA Technical Reports Server (NTRS)

    Kelly, W. L.; Benz, H. F.; Meredith, B. D.

    1980-01-01

    The Information Adaptive System (IAS) is an element of the NASA End-to-End Data System (NEEDS) Phase II and is focused toward onboard image processing. The IAS is a data preprocessing system which is closely coupled to the sensor system. Some of the functions planned for the IAS include sensor response nonuniformity correction, geometric correction, data set selection, data formatting, packetization, and adaptive system control. The inclusion of these sensor data preprocessing functions onboard the spacecraft will significantly improve the extraction of information from the sensor data in a timely and cost effective manner, and provide the opportunity to design sensor systems which can be reconfigured in near real-time for optimum performance. The purpose of this paper is to present the preliminary design of the IAS and the plans for its development.

  2. Materials management information systems.

    PubMed

    1996-01-01

    The hospital materials management function--ensuring that goods and services get from a source to an end user--encompasses many areas of the hospital and can significantly affect hospital costs. Performing this function in a manner that will keep costs down and ensure adequate cash flow requires effective management of a large amount of information from a variety of sources. To effectively coordinate such information, most hospitals have implemented some form of materials management information system (MMIS). These systems can be used to automate or facilitate functions such as purchasing, accounting, inventory management, and patient supply charges. In this study, we evaluated seven MMISs from seven vendors, focusing on the functional capabilities of each system and the quality of the service and support provided by the vendor. This Evaluation is intended to (1) assist hospitals purchasing an MMIS by educating materials managers about the capabilities, benefits, and limitations of MMISs and (2) educate clinical engineers and information system managers about the scope of materials management within a healthcare facility. Because software products cannot be evaluated in the same manner as most devices typically included in Health Devices Evaluations, our standard Evaluation protocol was not applicable for this technology. Instead, we based our ratings on our observations (e.g., during site visits), interviews we conducted with current users of each system, and information provided by the vendor (e.g., in response to a request for information [RFI]). We divided the Evaluation into the following sections: Section 1. Responsibilities and Information Requirements of Materials Management: Provides an overview of typical materials management functions and describes the capabilities, benefits, and limitations of MMISs. Also includes the supplementary article, "Inventory Cost and Reimbursement Issues" and the glossary, "Materials Management Terminology." Section 2. The

  3. Management Information System

    NASA Technical Reports Server (NTRS)

    1984-01-01

    New Automated Management Information Center (AMIC) employs innovative microcomputer techniques to create color charts, viewgraphs, or other data displays in a fraction of the time formerly required. Developed under Kennedy Space Center's contract by Boeing Services International Inc., Seattle, WA, AMIC can produce an entirely new informational chart in 30 minutes, or an updated chart in only five minutes. AMIC also has considerable potential as a management system for business firms.

  4. Training Management Information System

    SciTech Connect

    Rackley, M.P.

    1989-01-01

    The Training Management Information System (TMIS) is an integrated information system for all training related activities. TMIS is at the leading edge of training information systems used in the nuclear industry. The database contains all the necessary records to confirm the department's adherence to accreditation criteria and houses all test questions, student records and information needed to evaluate the training process. The key to the TMIS system is that the impact of any change (i.e., procedure change, new equipment, safety incident in the commercial nuclear industry, etc.) can be tracked throughout the training process. This ensures the best training can be performed that meets the needs of the employees. TMIS is comprised of six functional areas: Job and Task Analysis, Training Materials Design and Development, Exam Management, Student Records/Scheduling, Evaluation, and Commitment Tracking. The system consists of a VAX 6320 Cluster with IBM and MacIntosh computers tied into an ethernet with the VAX. Other peripherals are also tied into the system: Exam Generation Stations to include mark sense readers for test grading, Production PC's for Desk-Top Publishing of Training Material, and PC Image Workstations. 5 figs.

  5. CUAHSI Hydrologic Information System

    NASA Astrophysics Data System (ADS)

    Maidment, D. R.

    2005-12-01

    The Consortium of Universities for Advancement of Hydrologic Science, Inc. (CUAHSI) seeks to build a Hydrologic Information System (HIS) for which hydrologic data sources will be assembled in space and time to create a digital representation of atmospheric, surface and subsurface water flow through a watershed or other hydrologic system. A common data window for automatically accessing water observation data from US federal agencies is being developed based on web data services. Together with the related CLEANER program in environmental engineering, a cybercollaboratory is being used to foster remote access to data and shared research concerning its interpretation and model. A Digital Library to index hydrologic information within a river basin or aquifer has been developed and a Digital Watershed to synthesize observations, GIS, weather and climate grids and remote sensing is being designed and prootyped. Examples are presented from the Neuse basin in North Carolina and other locations to illustrate these components of a Hydrologic Information System.

  6. Geographic information systems

    NASA Technical Reports Server (NTRS)

    Campbell, W. J.

    1982-01-01

    Information and activities are provided to: (1) enhance the ability to distinguish between a Geographic Information System (GIS) and a data management system; (2) develop understanding of spatial data handling by conventional methods versus the automated approach; (3) promote awareness of GIS design and capabilities; (4) foster understanding of the concepts and problems of data base development and management; (5) facilitate recognition of how a computerized GIS can model conditions in the present "real world" to project conditions in the future; and (6) appreciate the utility of integrating LANDSAT and other remotely sensed data into the GIS.

  7. Geographic information systems

    NASA Technical Reports Server (NTRS)

    Campbell, W. J.

    1982-01-01

    Information and activities are provided to: (1) enhance the ability to distinguish between a Geographic Information System (GIS) and a data management system; (2) develop understanding of spatial data handling by conventional methods versus the automated approach; (3) promote awareness of GIS design and capabilities; (4) foster understanding of the concepts and problems of data base development and management; (5) facilitate recognition of how a computerized GIS can model conditions in the present "real world" to project conditions in the future; and (6) appreciate the utility of integrating LANDSAT and other remotely sensed data into the GIS.

  8. Global Land Information System

    USGS Publications Warehouse

    ,

    1999-01-01

    The Global Land Information System (GLIS) is a World Wide Web-based query tool developed by the U.S. Geological Survey (USGS) to provide data and information about the Earth's land surface. Examples of holdings available through the GLIS include cartographic data, topographic data, soils data, aerial photographs, and satellite images from various agencies and cooperators located around the world. Both hard copy and digital data collections are represented in the GLIS, and preview images are available for millions of the products in the system.

  9. Space Station information systems

    NASA Technical Reports Server (NTRS)

    Swingle, W. L.; Mckay, C. W.

    1983-01-01

    The space operations information system is defined and characterized in a wide perspective. Interactive subsets of the total system are defined and discussed. Particular attention is paid to the concept of end-to-end systems and their repetitive population within the total system. High level program goals are reviewed and related to more explicit system requirements and user needs. Emphasis is placed on the utility and cost effectiveness of data system services from a user standpoint. Productivity, as a quantitative goal, in both development and operational phases is also addressed. Critical aspects of the approach to successful development of the data management system are discussed along with recommendations important to advanced development activities. Current and planned activity in both technology and advanced development areas are reviewed with emphasis on their importance to program success.

  10. Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein

    SciTech Connect

    Jofuku, Akihiro; Ishihara, Naotada; Mihara, Katsuyoshi . E-mail: mihara@cell.med.kyushu-u.ac.jp

    2005-07-29

    In yeast, mitochondrial-fission is regulated by the cytosolic dynamin-like GTPase (Dnm1p) in conjunction with a peripheral protein, Mdv1p, and a C-tail-anchored outer membrane protein, Fis1p. In mammals, a dynamin-related protein (Drp1) and Fis1 are involved in the mitochondrial-fission reaction as Dnm1 and Fis1 orthologues, respectively. The involvement of other component(s), such as the Mdv1 homologue, and the mechanisms regulating mitochondrial-fission remain unclear. Here, we identified rat Fis1 (rFis1) and analyzed its structure-function relationship. Blue-native-polyacrylamide gel electrophoresis revealed that rFis1 formed a {approx}200-kDa complex in the outer mitochondrial membrane. Its expression in HeLa cells promoted extensive mitochondrial fragmentation, and gene knock-down by RNAi induced extension of the mitochondrial networks. Taking advantage of these properties, we analyzed functional domains of rFis1. These experiments revealed that the N-terminal and C-terminal segments are both essential for oligomeric rFis1 interaction, and the middle TPR-like domains regulate proper oligomer assembly. Any mutations that disturb the proper oligomeric assembly compromise mitochondrial division-stimulating activity of rFis1.

  11. Hunting for Long-lived Protoplanetary Disks Observed with AKARI/FIS

    NASA Astrophysics Data System (ADS)

    Qiong, LIU; Yao, LIU

    2015-10-01

    Twenty-one YSO (Young Stellar Object) candidates nearby the solar system have been identified through cross-correlating Hipparcos (High Precision Parallax Collecting Satellite) catalog with the AKARI/FIS YSO catalog, and the reliability is over 90%. The central objects cover the spectral types from B to M. The Hipparcos's accurate measurements of trigonometric parallaxes enable us to place these objects in the H-R diagram, which can be used to determine their ages by the isochrones of theoretical evolution trajectories. In this sample, two YSOs have been found to be older than 10 Myr. The spectral energy distributions (SEDs) from optical to infrared show that the two YSOs belong to the type II YSOs with protoplanetary disks. Furthermore, from the SED fitting, the ages of these two sources are constrained to be (14.1±4.2) Myr and (16.8±4.4) Myr, respectively. Therefore, two YSO candidates with long-lived protoplanetary disks have been detected in the AKARI/FIS data. The long-lived protoplanetary disks are closely related with the planet formation, and they are ideal birthplaces of protoplanets.

  12. Insect barcode information system.

    PubMed

    Pratheepa, Maria; Jalali, Sushil Kumar; Arokiaraj, Robinson Silvester; Venkatesan, Thiruvengadam; Nagesh, Mandadi; Panda, Madhusmita; Pattar, Sharath

    2014-01-01

    Insect Barcode Information System called as Insect Barcode Informática (IBIn) is an online database resource developed by the National Bureau of Agriculturally Important Insects, Bangalore. This database provides acquisition, storage, analysis and publication of DNA barcode records of agriculturally important insects, for researchers specifically in India and other countries. It bridges a gap in bioinformatics by integrating molecular, morphological and distribution details of agriculturally important insects. IBIn was developed using PHP/My SQL by using relational database management concept. This database is based on the client- server architecture, where many clients can access data simultaneously. IBIn is freely available on-line and is user-friendly. IBIn allows the registered users to input new information, search and view information related to DNA barcode of agriculturally important insects.This paper provides a current status of insect barcode in India and brief introduction about the database IBIn. http://www.nabg-nbaii.res.in/barcode.

  13. Pharmacology Information System Ready

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1973

    1973-01-01

    Discusses the development and future of Prophet,'' a specialized information handling system for pharmacology research. It is designed to facilitate the acquisition and dissemination of knowledge about mechanisms of drug action, and it is hoped that it will aid in converting pharmacology research from an empirical to a predictive science. (JR)

  14. Management Information Systems.

    ERIC Educational Resources Information Center

    Finlayson, Jean, Ed.

    1989-01-01

    This collection of papers addresses key questions facing college managers and others choosing, introducing, and living with big, complex computer-based systems. "What Use the User Requirement?" (Tony Coles) stresses the importance of an information strategy driven by corporate objectives, not technology. "Process of Selecting a…

  15. Pharmacology Information System Ready

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1973

    1973-01-01

    Discusses the development and future of Prophet,'' a specialized information handling system for pharmacology research. It is designed to facilitate the acquisition and dissemination of knowledge about mechanisms of drug action, and it is hoped that it will aid in converting pharmacology research from an empirical to a predictive science. (JR)

  16. Communication and Information Systems.

    ERIC Educational Resources Information Center

    Wheeler, Peter

    1982-01-01

    Discusses the Microelectronics Education Programme's work in the communication and information systems domain, suggesting that teachers understanding the new technologies and incorporate them into regular classroom instruction. Focuses on computers in the classroom, economy of time, keyboard skills, life skills, and vocational training. (Author/JN)

  17. Statistical Information Retrieval System.

    ERIC Educational Resources Information Center

    DiFondi, Nicholas M.

    An information retrieval system was developed using technical word occurrences as a basis for classification. A set of words, designated a vocabulary, was selected from the middle range of frequency listing of words occurring in an experimental sample of 94 documents. The selection produced 115 non-function words with technical definition that did…

  18. Geographic information systems

    USGS Publications Warehouse

    ,

    1992-01-01

    Geographic information systems (GIS) technology can be used for scientific investigations, resource management, and developmental planning. For example, a GIS might allow emergency planners to easily calculate emergency response times in the event of a natural disaster, or a GIS might be used to find wetlands that need protection form pollution.

  19. Toward intelligent information system

    NASA Astrophysics Data System (ADS)

    Takano, Fumio; Hinatsu, Ken'ichi

    This article describes the indexing aid system and project at JICST, API, NLM and BIOSIS. They are dealing with the very broad domain of science, medicine and technological literatures and indexing is done by use of controlled terms, the indexing is routinely performed by highly skilled indexers. Because of the high cost of controlled indexing of bibliographic information they have designed automated indexing system and/or expert-like system to take advantage of many years of experienced indexing using knowledge bases and /on thesauri.

  20. Laboratory Information Systems.

    PubMed

    Henricks, Walter H

    2015-06-01

    Laboratory information systems (LISs) supply mission-critical capabilities for the vast array of information-processing needs of modern laboratories. LIS architectures include mainframe, client-server, and thin client configurations. The LIS database software manages a laboratory's data. LIS dictionaries are database tables that a laboratory uses to tailor an LIS to the unique needs of that laboratory. Anatomic pathology LIS (APLIS) functions play key roles throughout the pathology workflow, and laboratories rely on LIS management reports to monitor operations. This article describes the structure and functions of APLISs, with emphasis on their roles in laboratory operations and their relevance to pathologists.

  1. Nuclear criticality information system

    SciTech Connect

    Koponen, B.L.; Hampel, V.E.

    1981-11-30

    The nuclear criticality safety program at LLNL began in the 1950's with a critical measurements program which produced benchmark data until the late 1960's. This same time period saw the rapid development of computer technology useful for both computer modeling of fissile systems and for computer-aided management and display of the computational benchmark data. Database management grew in importance as the amount of information increased and as experimental programs were terminated. Within the criticality safety program at LLNL we began at that time to develop a computer library of benchmark data for validation of computer codes and cross sections. As part of this effort, we prepared a computer-based bibliography of criticality measurements on relatively simple systems. However, it is only now that some of these computer-based resources can be made available to the nuclear criticality safety community at large. This technology transfer is being accomplished by the DOE Technology Information System (TIS), a dedicated, advanced information system. The NCIS database is described.

  2. Information Systems in Dentistry

    PubMed Central

    Masic, Fedja

    2012-01-01

    Introduction: Almost the entire human creativity today, from the standpoint of its efficiency and expediency, is conditioned with the existence of information systems. Most information systems are oriented to the management and decision-making, including health information system. System of health and health insurance together form one of the most important segments of society and its functioning as a compact unit. Increasing requirements for reducing health care costs while preserving or improving the quality of services provided represent a difficult task for the health system. Material and methods: Using descriptive metods by retreiiving literature we analyzed the latest solutions in information and telecommunications technology is the basis for building an effective and efficient health system. Computerization does not have the primary objective of saving, but the rationalization of spending in health care. It is estimated that at least 20-30% of money spent in health care can be rationally utilized. Computerization should give the necessary data and indicators for this rationalization. Very important are the goals of this project and the achievement of other uses and benefits, improving overall care for patients and policyholders, increasing the speed and accuracy of diagnosis in determining treatment using electronic diagnostic and therapeutic guidelines. Results and discussion: Computerization in dentistry began similarly as in other human activities–recording large amounts of data on digital media, and by replacing manual data processing to machine one. But specifics of the dental profession have led to the specifics of the application of information technology (IT), and continue to require special development of dental oriented and applied IT. Harmonization of dental software with global standards will enable doctors and dentists to with a few mouse clicks via the internet reach the general medical information about their patients from the central

  3. Du Pont Information Flow System

    ERIC Educational Resources Information Center

    Hoffman, Warren S.

    1972-01-01

    The Information Flow System is a large-scale information retrieval system developed for processing of Du Pont information files. As currently implemented, the system stores and retrieves information on company technical reports. Extensions of the system for handling chemical structure information and on-line processing are also discussed. (3…

  4. Information sciences experiment system

    NASA Technical Reports Server (NTRS)

    Katzberg, Stephen J.; Murray, Nicholas D.; Benz, Harry F.; Bowker, David E.; Hendricks, Herbert D.

    1990-01-01

    The rapid expansion of remote sensing capability over the last two decades will take another major leap forward with the advent of the Earth Observing System (Eos). An approach is presented that will permit experiments and demonstrations in onboard information extraction. The approach is a non-intrusive, eavesdropping mode in which a small amount of spacecraft real estate is allocated to an onboard computation resource. How such an approach allows the evaluation of advanced technology in the space environment, advanced techniques in information extraction for both Earth science and information science studies, direct to user data products, and real-time response to events, all without affecting other on-board instrumentation is discussed.

  5. CUAHSI Hydrologic Information Systems

    NASA Astrophysics Data System (ADS)

    Maidment, D.; Zaslavsky, I.; Tarboton, D.; Piasecki, M.; Goodall, J.

    2006-12-01

    The Consortium of Universities for the Advancement of Hydrologic Science, Inc (CUAHSI) has a Hydrologic Information System (HIS) project, which is supported by NSF to develop infrastructure and services to support the advance of hydrologic science in the United States. This paper provides an overview of the HIS project. A set of web services called WaterOneFlow is being developed to provide better access to water observations data (point measurements of streamflow, water quality, climate and groundwater levels) from government agencies and individual investigator projects. Successful partnerships have been created with the USGS National Water Information System, EPA Storet and the NCDC Climate Data Online. Observations catalogs have been created for stations in the measurement networks of each of these data systems so that they can be queried in a uniform manner through CUAHSI HIS, and data delivered from them directly to the user via web services. A CUAHSI Observations Data Model has been designed for storing individual investigator data and an equivalent set of web services created for that so that individual investigators can publish their data onto the internet in the same format CUAHSI is providing for the federal agency data. These data will be accessed through HIS Servers hosted at the national level by CUAHSI and also by research centers and academic departments for regional application of HIS. An individual user application called HIS Analyst will enable individual hydrologic scientists to access the information from the network of HIS Servers. The present focus is on water observations data but later development of this system will include weather and climate grid information, GIS data, remote sensing data and linkages between data and hydrologic simulation models.

  6. Engineering Review Information System

    NASA Technical Reports Server (NTRS)

    Grems, III, Edward G. (Inventor); Henze, James E. (Inventor); Bixby, Jonathan A. (Inventor); Roberts, Mark (Inventor); Mann, Thomas (Inventor)

    2015-01-01

    A disciplinal engineering review computer information system and method by defining a database of disciplinal engineering review process entities for an enterprise engineering program, opening a computer supported engineering item based upon the defined disciplinal engineering review process entities, managing a review of the opened engineering item according to the defined disciplinal engineering review process entities, and closing the opened engineering item according to the opened engineering item review.

  7. Symposium on Geographic Information Systems.

    ERIC Educational Resources Information Center

    Felleman, John, Ed.

    1990-01-01

    Six papers on geographic information systems cover the future of geographic information systems, land information systems modernization in Wisconsin, the Topologically Integrated Geographic Encoding and Referencing (TIGER) System of the U.S. Bureau of the Census, satellite remote sensing, geographic information systems and sustainable development,…

  8. An evaluation framework for Health Information Systems: human, organization and technology-fit factors (HOT-fit).

    PubMed

    Yusof, Maryati Mohd; Kuljis, Jasna; Papazafeiropoulou, Anastasia; Stergioulas, Lampros K

    2008-06-01

    The realization of Health Information Systems (HIS) requires rigorous evaluation that addresses technology, human and organization issues. Our review indicates that current evaluation methods evaluate different aspects of HIS and they can be improved upon. A new evaluation framework, human, organization and technology-fit (HOT-fit) was developed after having conducted a critical appraisal of the findings of existing HIS evaluation studies. HOT-fit builds on previous models of IS evaluation--in particular, the IS Success Model and the IT-Organization Fit Model. This paper introduces the new framework for HIS evaluation that incorporates comprehensive dimensions and measures of HIS and provides a technological, human and organizational fit. Literature review on HIS and IS evaluation studies and pilot testing of developed framework. The framework was used to evaluate a Fundus Imaging System (FIS) of a primary care organization in the UK. The case study was conducted through observation, interview and document analysis. The main findings show that having the right user attitude and skills base together with good leadership, IT-friendly environment and good communication can have positive influence on the system adoption. Comprehensive, specific evaluation factors, dimensions and measures in the new framework (HOT-fit) are applicable in HIS evaluation. The use of such a framework is argued to be useful not only for comprehensive evaluation of the particular FIS system under investigation, but potentially also for any Health Information System in general.

  9. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

    SciTech Connect

    Stella, Stefano; Cascio, Duilio; Johnson, Reid C.

    2010-06-21

    The bacterial nucleoid-associated protein Fis regulates diverse reactions by bending DNA and through DNA-dependent interactions with other control proteins and enzymes. In addition to dynamic nonspecific binding to DNA, Fis forms stable complexes with DNA segments that share little sequence conservation. Here we report the first crystal structures of Fis bound to high- and low-affinity 27-base-pair DNA sites. These 11 structures reveal that Fis selects targets primarily through indirect recognition mechanisms involving the shape of the minor groove and sequence-dependent induced fits over adjacent major groove interfaces. The DNA shows an overall curvature of {approx}65{sup o}, and the unprecedented close spacing between helix-turn-helix motifs present in the apodimer is accommodated by severe compression of the central minor groove. In silico DNA structure models show that only the roll, twist, and slide parameters are sufficient to reproduce the changes in minor groove widths and recreate the curved Fis-bound DNA structure. Models based on naked DNA structures suggest that Fis initially selects DNA targets with intrinsically narrow minor grooves using the separation between helix-turn-helix motifs in the Fis dimer as a ruler. Then Fis further compresses the minor groove and bends the DNA to generate the bound structure.

  10. FisB mediates membrane fission during sporulation in Bacillus subtilis

    PubMed Central

    Doan, Thierry; Coleman, Jeff; Marquis, Kathleen A.; Meeske, Alex J.; Burton, Briana M.; Karatekin, Erdem; Rudner, David Z.

    2013-01-01

    How bacteria catalyze membrane fission during growth and differentiation is an outstanding question in prokaryotic cell biology. Here, we describe a protein (FisB, for fission protein B) that mediates membrane fission during the morphological process of spore formation in Bacillus subtilis. Sporulating cells divide asymmetrically, generating a large mother cell and smaller forespore. After division, the mother cell membranes migrate around the forespore in a phagocytic-like process called engulfment. Membrane fission releases the forespore into the mother cell cytoplasm. Cells lacking FisB are severely and specifically impaired in the fission reaction. Moreover, GFP-FisB forms dynamic foci that become immobilized at the site of fission. Purified FisB catalyzes lipid mixing in vitro and is only required in one of the fusing membranes, suggesting that FisB–lipid interactions drive membrane remodeling. Consistent with this idea, the extracytoplasmic domain of FisB binds with remarkable specificity to cardiolipin, a lipid enriched in the engulfing membranes and regions of negative curvature. We propose that membrane topology at the final stage of engulfment and FisB–cardiolipin interactions ensure that the mother cell membranes are severed at the right time and place. The unique properties of FisB set it apart from the known fission machineries in eukaryotes, suggesting that it represents a new class of fission proteins. PMID:23388828

  11. FisB mediates membrane fission during sporulation in Bacillus subtilis.

    PubMed

    Doan, Thierry; Coleman, Jeff; Marquis, Kathleen A; Meeske, Alex J; Burton, Briana M; Karatekin, Erdem; Rudner, David Z

    2013-02-01

    How bacteria catalyze membrane fission during growth and differentiation is an outstanding question in prokaryotic cell biology. Here, we describe a protein (FisB, for fission protein B) that mediates membrane fission during the morphological process of spore formation in Bacillus subtilis. Sporulating cells divide asymmetrically, generating a large mother cell and smaller forespore. After division, the mother cell membranes migrate around the forespore in a phagocytic-like process called engulfment. Membrane fission releases the forespore into the mother cell cytoplasm. Cells lacking FisB are severely and specifically impaired in the fission reaction. Moreover, GFP-FisB forms dynamic foci that become immobilized at the site of fission. Purified FisB catalyzes lipid mixing in vitro and is only required in one of the fusing membranes, suggesting that FisB-lipid interactions drive membrane remodeling. Consistent with this idea, the extracytoplasmic domain of FisB binds with remarkable specificity to cardiolipin, a lipid enriched in the engulfing membranes and regions of negative curvature. We propose that membrane topology at the final stage of engulfment and FisB-cardiolipin interactions ensure that the mother cell membranes are severed at the right time and place. The unique properties of FisB set it apart from the known fission machineries in eukaryotes, suggesting that it represents a new class of fission proteins.

  12. The Mitochondrial Fission Protein hFis1 Requires the Endoplasmic Reticulum Gateway to Induce Apoptosis

    PubMed Central

    Alirol, Emilie; James, Dominic; Huber, Denise; Marchetto, Andrea; Vergani, Lodovica

    2006-01-01

    Mitochondrial fission ensures organelle inheritance during cell division and participates in apoptosis. The fission protein hFis1 triggers caspase-dependent cell death, by causing the release of cytochrome c from mitochondria. Here we show that mitochondrial fission induced by hFis1 is genetically distinct from apoptosis. In cells lacking the multidomain proapoptotic Bcl-2 family members Bax and Bak (DKO), hFis1 caused mitochondrial fragmentation but not organelle dysfunction and apoptosis. Similarly, a mutant in the intermembrane region of hFis1-induced fission but not cell death, further dissociating mitochondrial fragmentation from apoptosis induction. Selective correction of the endoplasmic reticulum (ER) defect of DKO cells restored killing by hFis1, indicating that death by hFis1 relies on the ER gateway of apoptosis. Consistently, hFis1 did not directly activate BAX and BAK, but induced Ca2+-dependent mitochondrial dysfunction. Thus, hFis1 is a bifunctional protein that independently regulates mitochondrial fragmentation and ER-mediated apoptosis. PMID:16914522

  13. MANAGEMENT INFORMATION SYSTEM,

    DTIC Science & Technology

    Management Information System being developed for the Institute of Cybernetics of the Academy of Sciences of the Ukrainian SSR. The work is being done at the suggestion of Academician V. M. Glushkov under the leadership of Candidate of Physico-Mathematical Sciences A. A. Stognii. Projects reports prepared in various departments of the Institute of Cybernetics in 1963-64 were used in writing this paper. Among them, the works of V. N. Afanas’ev, V. G Bodnarchuk, E. F. Skorokhod’ko, and V. I. Shurikhin should be mentioned. A great deal of factural

  14. Interstellar reddening information system

    NASA Astrophysics Data System (ADS)

    Burnashev, V. I.; Grigorieva, E. A.; Malkov, O. Yu.

    2013-10-01

    We describe an electronic bibliographic information system, based on a card catalog, containing some 2500 references (publications of 1930-2009) on interstellar extinction. We have classified the articles according to their content. We present here a list of articles devoted to two categories: maps of total extinction and variation of interstellar extinction with the distance to the object. The catalog is tested using published data on open clusters, and conclusions on the applicability of different maps of interstellar extinctions for various distances are made.

  15. Advanced information processing system

    NASA Technical Reports Server (NTRS)

    Lala, J. H.

    1984-01-01

    Design and performance details of the advanced information processing system (AIPS) for fault and damage tolerant data processing on aircraft and spacecraft are presented. AIPS comprises several computers distributed throughout the vehicle and linked by a damage tolerant data bus. Most I/O functions are available to all the computers, which run in a TDMA mode. Each computer performs separate specific tasks in normal operation and assumes other tasks in degraded modes. Redundant software assures that all fault monitoring, logging and reporting are automated, together with control functions. Redundant duplex links and damage-spread limitation provide the fault tolerance. Details of an advanced design of a laboratory-scale proof-of-concept system are described, including functional operations.

  16. The AMMA information system

    NASA Astrophysics Data System (ADS)

    Fleury, Laurence; Brissebrat, Guillaume; Boichard, Jean-Luc; Cloché, Sophie; Eymard, Laurence; Mastrorillo, Laurence; Moulaye, Oumarou; Ramage, Karim; Favot, Florence; Roussot, Odile

    2014-05-01

    In the framework of the African Monsoon Multidisciplinary Analyses (AMMA) programme, several tools have been developed in order to facilitate and speed up data and information exchange between researchers from different disciplines. The AMMA information system includes (i) a multidisciplinary user-friendly data management and dissemination system, (ii) report and chart archives associated with display websites and (iii) a scientific paper exchange system. The AMMA information system is enriched by several previous (IMPETUS...) and following projects (FENNEC, ESCAPE, QweCI, DACCIWA…) and is becoming a reference information system about West Africa monsoon. (i) The AMMA project includes airborne, ground-based and ocean measurements, satellite data use, modelling studies and value-added product development. Therefore, the AMMA database user interface enables to access a great amount and a large variety of data: - 250 local observation datasets, that cover many geophysical components (atmosphere, ocean, soil, vegetation) and human activities (agronomy, health). They have been collected by operational networks from 1850 to present, long term monitoring research networks (CATCH, IDAF, PIRATA...) or scientific campaigns; - 1350 outputs of a socio-economics questionnaire; - 60 operational satellite products and several research products; - 10 output sets of meteorological and ocean operational models and 15 of research simulations. All the data are documented in compliance with metadata international standards, and delivered into standard formats. The data request user interface takes full advantage of the data and metadata base relational structure and enables users to elaborate easily multicriteria data requests (period, area, property, property value…). The AMMA data portal counts around 800 registered users and process about 50 data requests every month. The AMMA databases and data portal have been developed and are operated jointly by SEDOO and ESPRI in France

  17. The AMMA information system

    NASA Astrophysics Data System (ADS)

    Fleury, Laurence; Brissebrat, Guillaume; Boichard, Jean-Luc; Cloché, Sophie; Mière, Arnaud; Moulaye, Oumarou; Ramage, Karim; Favot, Florence; Boulanger, Damien

    2015-04-01

    In the framework of the African Monsoon Multidisciplinary Analyses (AMMA) programme, several tools have been developed in order to boost the data and information exchange between researchers from different disciplines. The AMMA information system includes (i) a user-friendly data management and dissemination system, (ii) quasi real-time display websites and (iii) a scientific paper exchange collaborative tool. The AMMA information system is enriched by past and ongoing projects (IMPETUS, FENNEC, ESCAPE, QweCI, ACASIS, DACCIWA...) addressing meteorology, atmospheric chemistry, extreme events, health, adaptation of human societies... It is becoming a reference information system on environmental issues in West Africa. (i) The projects include airborne, ground-based and ocean measurements, social science surveys, satellite data use, modelling studies and value-added product development. Therefore, the AMMA data portal enables to access a great amount and a large variety of data: - 250 local observation datasets, that cover many geophysical components (atmosphere, ocean, soil, vegetation) and human activities (agronomy, health). They have been collected by operational networks since 1850, long term monitoring research networks (CATCH, IDAF, PIRATA...) and intensive scientific campaigns; - 1350 outputs of a socio-economics questionnaire; - 60 operational satellite products and several research products; - 10 output sets of meteorological and ocean operational models and 15 of research simulations. Data documentation complies with metadata international standards, and data are delivered into standard formats. The data request interface takes full advantage of the database relational structure and enables users to elaborate multicriteria requests (period, area, property, property value…). The AMMA data portal counts about 900 registered users, and 50 data requests every month. The AMMA databases and data portal have been developed and are operated jointly by SEDOO and

  18. Nanophotonics for information systems

    NASA Astrophysics Data System (ADS)

    Nezhad, M.; Abashin, M.; Ikeda, K.; Pang, L.; Kim, H. C.; Levy, U.; Tetz, K.; Rokitski, R.; Fainman, Y.

    2007-02-01

    Optical technology plays an increasingly important role in numerous applications areas, including communications, information processing, and data storage. However, as optical technology develops, it is evident that there is a growing need to develop reliable photonic integration technologies. This will include the development of passive as well as active optical components that can be integrated into functional optical circuits and systems, including filters, switching fabrics that can be controlled either electrically or optically, optical sources, detectors, amplifiers, etc. We explore the unique capabilities and advantages of nanotechnology in developing next generation integrated photonic chips. Our long-range goal is to develop a range of photonic nanostructures including artificially birefringent and resonant devices, photonic crystals, and photonic crystals with defects to tailor spectral filters, and nanostructures for spatial field localization to enhance optical nonlinearities, to facilitate on-chip system integration through compatible materials and fabrication processes. The design of artificial nanostructured materials, PCs and integrated photonic systems is one of the most challenging tasks as it not only involves the accurate solution of electromagnetic optics equations, but also the need to incorporate the material and quantum physics equations. Near-field interactions in artificial nanostructured materials provide a variety of functionalities useful for optical systems integration. Recently, the inclusion of surface plasmon photonics in this area has opened up a host of new possibilities Finally and most importantly, nanophotonics may enable easier integration with other nanotechnologies: electronics, magnetics, mechanics, chemistry, and biology. We will address some of these areas in this paper.

  19. Layers of Information: Geographic Information Systems (GIS).

    ERIC Educational Resources Information Center

    Lucking, Robert A.; Christmann, Edwin P.

    2003-01-01

    Describes the Geographic Information System (GIS) which is capable of storing, manipulating, and displaying data allowing students to explore complex relationships through scientific inquiry. Explains applications of GIS in middle school classrooms and includes assessment strategies. (YDS)

  20. Layers of Information: Geographic Information Systems (GIS).

    ERIC Educational Resources Information Center

    Lucking, Robert A.; Christmann, Edwin P.

    2003-01-01

    Describes the Geographic Information System (GIS) which is capable of storing, manipulating, and displaying data allowing students to explore complex relationships through scientific inquiry. Explains applications of GIS in middle school classrooms and includes assessment strategies. (YDS)

  1. Geographic Information Systems.

    PubMed

    Wieczorek, William F; Delmerico, Alan M

    2009-01-01

    This chapter presents an overview of the development, capabilities, and utilization of geographic information systems (GIS). There are nearly an unlimited number of applications that are relevant to GIS because virtually all human interactions, natural and man-made features, resources, and populations have a geographic component. Everything happens somewhere and the location often has a role that affects what occurs. This role is often called spatial dependence or spatial autocorrelation, which exists when a phenomenon is not randomly geographically distributed. GIS has a number of key capabilities that are needed to conduct a spatial analysis to assess this spatial dependence. This chapter presents these capabilities (e.g., georeferencing, adjacency/distance measures, overlays) and provides a case study to illustrate how GIS can be used for both research and planning. Although GIS has developed into a relatively mature application for basic functions, development is needed to more seamlessly integrate spatial statistics and models.The issue of location, especially the geography of human activities, interactions between humanity and nature, and the distribution and location of natural resources and features, is one of the most basic elements of scientific inquiry. Conceptualizations and physical maps of geographic space have existed since the beginning of time because all human activity takes place in a geographic context. Representing objects in space, basically where things are located, is a critical aspect of the natural, social, and applied sciences. Throughout history there have been many methods of characterizing geographic space, especially maps created by artists, mariners, and others eventually leading to the development of the field of cartography. It is no surprise that the digital age has launched a major effort to utilize geographic data, but not just as maps. A geographic information system (GIS) facilitates the collection, analysis, and reporting of

  2. Geographic Information Systems

    PubMed Central

    Wieczorek, William F.; Delmerico, Alan M.

    2009-01-01

    This chapter presents an overview of the development, capabilities, and utilization of geographic information systems (GIS). There are nearly an unlimited number of applications that are relevant to GIS because virtually all human interactions, natural and man-made features, resources, and populations have a geographic component. Everything happens somewhere and the location often has a role that affects what occurs. This role is often called spatial dependence or spatial autocorrelation, which exists when a phenomenon is not randomly geographically distributed. GIS has a number of key capabilities that are needed to conduct a spatial analysis to assess this spatial dependence. This chapter presents these capabilities (e.g., georeferencing, adjacency/distance measures, overlays) and provides a case study to illustrate how GIS can be used for both research and planning. Although GIS has developed into a relatively mature application for basic functions, development is needed to more seamlessly integrate spatial statistics and models. The issue of location, especially the geography of human activities, interactions between humanity and nature, and the distribution and location of natural resources and features, is one of the most basic elements of scientific inquiry. Conceptualizations and physical maps of geographic space have existed since the beginning of time because all human activity takes place in a geographic context. Representing objects in space, basically where things are located, is a critical aspect of the natural, social, and applied sciences. Throughout history there have been many methods of characterizing geographic space, especially maps created by artists, mariners, and others eventually leading to the development of the field of cartography. It is no surprise that the digital age has launched a major effort to utilize geographic data, but not just as maps. A geographic information system (GIS) facilitates the collection, analysis, and reporting of

  3. Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.

    PubMed

    Suzuki, Motoshi; Neutzner, Albert; Tjandra, Nico; Youle, Richard J

    2005-06-03

    Mitochondrial fission is facilitated by a multiprotein complex assembled at the division site. The required components of the fission machinery in Saccharomyces cerevisiae include Dnm1, Fis1, and Mdv1. In the present study, we determined the protein structure of yeast Fis1 using NMR spectroscopy. Although the six alpha-helices, as well as their folding, in the yeast Fis1 structure are similar to those of the tetratricopeptide repeat (TPR) domains of the human Fis1 structure, the two structures differ in their N termini. The N-terminal tail of human Fis1 is flexible and unstructured, whereas a major segment of the longer N terminus of yeast Fis1 is fixed to the concave face formed by the six alpha-helices in the TPR domains. To investigate the role of the fixed N terminus, exogenous Fis1 was expressed in yeast lacking the endogenous protein. Expression of yeast Fis1 protein rescued mitochondrial fission in delta fis1 yeast only when the N-terminal TPR binding segment was left intact. The presence of this segment is also correlated to the recruitment of Mdv1 to mitochondria. The conformation of the N-terminal segment embedded in the TPR pocket indicates an intra-molecular regulation of Fis1 bioactivity. Although the TPR-like helix bundle of Fis1 mediates the interaction with Dnm1 and Mdv1, the N terminus of Fis1 is a prerequisite to recruit Mdv1 to facilitate mitochondrial fission.

  4. Iowa Flood Information System

    NASA Astrophysics Data System (ADS)

    Demir, I.; Krajewski, W. F.; Goska, R.; Mantilla, R.; Weber, L. J.; Young, N.

    2011-12-01

    The Iowa Flood Information System (IFIS) is a web-based platform developed by the Iowa Flood Center (IFC) to provide access to flood inundation maps, real-time flood conditions, flood forecasts both short-term and seasonal, flood-related data, information and interactive visualizations for communities in Iowa. The key element of the system's architecture is the notion of community. Locations of the communities, those near streams and rivers, define basin boundaries. The IFIS provides community-centric watershed and river characteristics, weather (rainfall) conditions, and streamflow data and visualization tools. Interactive interfaces allow access to inundation maps for different stage and return period values, and flooding scenarios with contributions from multiple rivers. Real-time and historical data of water levels, gauge heights, and rainfall conditions are available in the IFIS by streaming data from automated IFC bridge sensors, USGS stream gauges, NEXRAD radars, and NWS forecasts. Simple 2D and 3D interactive visualizations in the IFIS make the data more understandable to general public. Users are able to filter data sources for their communities and selected rivers. The data and information on IFIS is also accessible through web services and mobile applications. The IFIS is optimized for various browsers and screen sizes to provide access through multiple platforms including tablets and mobile devices. The IFIS includes a rainfall-runoff forecast model to provide a five-day flood risk estimate for around 500 communities in Iowa. Multiple view modes in the IFIS accommodate different user types from general public to researchers and decision makers by providing different level of tools and details. River view mode allows users to visualize data from multiple IFC bridge sensors and USGS stream gauges to follow flooding condition along a river. The IFIS will help communities make better-informed decisions on the occurrence of floods, and will alert communities

  5. [Geographic information systems].

    PubMed

    Hernández-Vásquez, Akram; Azañedo, Diego; Bendezú-Quispe, Guido; Pacheco-Mendoza, Josmel; Chaparro, R Martín

    2016-01-01

    The aim of this study was to geospatially explore the occurrence rates of car accidents involving pedestrians in Cercado de Lima (Lima District), Peru. Car accidents involving pedestrians recorded in the 2015 National Police Station Census of the National Statistics and Information Institute were described and georeferenced. Subsequently, a Kernel Density analysis was carried out to locate areas with high, medium, and low density events. Records of 171 car accidents involving pedestrians were studied: the types of vehicles involved were automobiles (56.7%) and smaller vehicles (22.8%). The highest percentage of car accidents involving pedestrians (38.6%) took place between 12:00 p.m. and 5:00 p.m. There were two densely populated areas and two areas with intermediate density for car accidents involving pedestrians, locations that were previously reported as critical due to their deficiencies and high probability of traffic accidents. The use of geographic information systems offers a quick overview of the occurrence rates of car accidents involving pedestrians to make comparisons and enable the local implementation of strategies.

  6. A Role for Fis1 in Both Mitochondrial and Peroxisomal Fission in Mammalian CellsD⃞

    PubMed Central

    Koch, Annett; Yoon, Yisang; Bonekamp, Nina A.; McNiven, Mark A.; Schrader, Michael

    2005-01-01

    The mammalian dynamin-like protein DLP1/Drp1 has been shown to mediate both mitochondrial and peroxisomal fission. In this study, we have examined whether hFis1, a mammalian homologue of yeast Fis1, which has been shown to participate in mitochondrial fission by an interaction with DLP1/Drp1, is also involved in peroxisomal growth and division. We show that hFis1 localizes to peroxisomes in addition to mitochondria. Through differential tagging and deletion experiments, we demonstrate that the transmembrane domain and the short C-terminal tail of hFis1 is both necessary and sufficient for its targeting to peroxisomes and mitochondria, whereas the N-terminal region is required for organelle fission. hFis1 promotes peroxisome division upon ectopic expression, whereas silencing of Fis1 by small interfering RNA inhibited fission and caused tubulation of peroxisomes. These findings provide the first evidence for a role of Fis1 in peroxisomal fission and suggest that the fission machinery of mitochondria and peroxisomes shares common components. PMID:16107562

  7. Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis

    SciTech Connect

    Kobayashi, Shinta; Tanaka, Atsushi; Fujiki, Yukio . E-mail: yfujiscb@mbox.nc.kyushu-u.ac.jp

    2007-05-01

    Dynamin-like protein 1 (DLP1) and Pex11p{beta} function in morphogenesis of peroxisomes. In the present work, we investigated whether Fis1 is involved in fission of peroxisomes. Endogenous Fis1 was morphologically detected in peroxisomes as well as mitochondria in wild-type CHO-K1 and DLP1-defective ZP121 cells. Subcellular fractionation studies also revealed the presence of Fis1 in peroxisomes. Peroxisomal Fis1 showed the same topology, i.e., C-tail anchored membrane protein, as the mitochondrial one. Furthermore, ectopic expression of FIS1 induced peroxisome proliferation in CHO-K1 cells, while the interference of FIS1 RNA resulted in tubulation of peroxisomes, hence reducing the number of peroxisomes. Fis1 interacted with Pex11p{beta}, by direct binding apparently involving the C-terminal region of Pex11p{beta} in the interaction. Pex11p{beta} also interacted with each other, whereas the binding of Pex11p{beta} to DLP1 was not detectable. Moreover, ternary complexes comprising Fis1, Pex11p{beta}, and DLP1 were detected by chemical cross-linking. We also showed that the highly conserved N-terminal domain of Pex11p{beta} was required for the homo-oligomerization of Pex11p{beta} and indispensable for the peroxisome-proliferating activity. Taken together, these findings indicate that Fis1 plays important roles in peroxisome division and maintenance of peroxisome morphology in mammalian cells, possibly in a concerted manner with Pex11p{beta} and DLP1.

  8. Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae.

    PubMed

    Picton, Lora K; Casares, Salvador; Monahan, Ann C; Majumdar, Ananya; Hill, R Blake

    2009-07-21

    Fission 1 (Fis1) is an evolutionarily conserved, type II integral membrane protein implicated in maintaining the proper morphology of mitochondria and peroxisomes. A concave surface on the cytosolic domain of Fis1 from Saccharomyces cerevisiae is implicated in binding other fission proteins, yet structural studies reveal that this surface is sterically occluded by its N-terminal arm. Here we address the question of whether the N-terminal arm of yeast Fis1 exists in a dynamic equilibrium that would allow access to this functionally important surface. NMR measurements sensitive to dynamics occurring on a wide range of time scales (picoseconds to minutes) were used to assess whether the Fis1 arm is dynamic. Hydrogen-deuterium exchange experiments revealed that the Fis1 arm, alpha-helix 6, and proximal loops were not protected from solvent exchange, consistent with motions on the second to minute time scale. An engineered cysteine, I85C, located on the concave surface that lies underneath the Fis1 arm, was readily modified by a fluorescent probe, revealing more solvent accessibility of this position than would be predicted from the structure. Chemical denaturation, NMR chemical shift perturbation, and residual dipolar coupling experiments support the idea that the dynamic equilibrium can be shifted on the basis of changing pH and temperature, with the changes primarily localizing to the Fis1 arm and proximal regions. The data as a whole are consistent with the Fis1 arm adopting a primarily "closed" conformational state able to undergo dynamic excursions that reveal the concave surface and therefore may be important for binding other fission factors and for Fis1 function.

  9. Family Impact Scale (FIS): Cross-cultural Adaptation and Psychometric Properties for the Peruvian Spanish Language.

    PubMed

    Abanto, Jenny; Albites, Ursula; Bönecker, Marcelo; Paiva, Saul M; Castillo, Jorge L; Aguilar-Gálvez, Denisse

    2015-12-01

    The lack of a Family Impact Scale (FIS) in Spanish language limits its use as an indicator in Spanish-speaking countries and precludes comparisons with data from other cultural and ethnic groups. The purpose of this study was therefore to adapt the FIS cross-culturally to the Peruvian Spanish language and assess its reliability and validity. In order to translate and adapt the FIS cross-culturally, it was answered by 60 parents in two pilot tests, after which it was tested on 200 parents of children aged 11 to 14 years who were clinically examined for dental caries experience and malocclusions. Internal consistency was assessed by Cronbach's alpha coefficient while repeat administration of the FIS on the same 200 parents enabled the test-retest reliability to be assessed via intraclass correlation coefficient (ICC). Construct and discriminant validity were based on associations of the FIS with global ratings of oral health and clinical groups, respectively. Mean (standard deviation) FIS total score was 5.20 (5.86). Internal consistency was confirmed by Cronbach's alpha 0.84. Test-retest reliability revealed excellent reproducibility (ICC = 0.96). Construct validity was good, demonstrating statistically significant associations between total FIS score and global ratings of oral health (p=0.007) and overall wellbeing (p=0.002), as well as for the subscale scores (p<0.05) with exception of the financial burden subscale. The FIS was also able to discriminate between children with and without dental caries experience and malocclusions (p<0.05). Satisfactory psychometric results for the Peruvian Spanish FIS confirm it as a reliable, valid instrument for assessing the impact on the family caused by children's oral conditions.

  10. Defense Energy Information System. Manual

    SciTech Connect

    Carnes, J.

    1990-02-01

    The Manual provides clear, reliable, timely, accurate, and objective energy information; prescribes instructions for the preparation and submission of energy data to support the Defense Energy Information System (DEIS); and furnishes information regarding the use of the DEIS.

  11. Federal Energy Information Systems.

    ERIC Educational Resources Information Center

    Coyne, Joseph G.; Moneyhun, Dora H.

    1979-01-01

    Describes the Energy Information Administration (EIA) and the Technical Information Center (TIC), and lists databases accessible online to the Department of Energy and its contractors through DOE/RECON. (RAA)

  12. The Phobos information system

    NASA Astrophysics Data System (ADS)

    Karachevtseva, I. P.; Oberst, J.; Zubarev, A. E.; Nadezhdina, I. E.; Kokhanov, A. A.; Garov, A. S.; Uchaev, D. V.; Uchaev, Dm. V.; Malinnikov, V. A.; Klimkin, N. D.

    2014-11-01

    We have developed a Geo-information system (GIS) for Phobos, based on data from the Mars Express and Viking Orbiter missions, which includes orthoimages, global maps, terrain- and gravity field models, all referenced to the Phobos coordinate system. The data are conveniently stored in the ArcGIS software system, which provides an environment for mapping and which allows us to carry out joint data analysis and miscellaneous data cross-comparisons. We have compiled catalogs of Phobos craters using manual and automated techniques, which includes about 5500 and 6400 craters correspondingly. While crater numbers are biased by available image data resolution and illumination, we estimate that our catalog of manually detected craters contains all Phobos craters with diameters D>250 m which is a total of 1072 and catalog of automated detected craters are complete for craters D>400 m (360 craters). Statistical analysis of these large craters reveals a surplus of craters on the anti-Mars hemisphere, whereas differences in crater abundance between leading and trailing hemisphere cannot be confirmed. This in contrast to previous papers, where no such asymmetry was found (Schmedemann et al., 2014). But we cannot rule out remaining biases due to resolution, viewing angles or illumination effects. Using digital terrain model (DTM) derived from photogrammetry image processing we estimate depths of 25 craters larger than 2 km using geometric and dynamic heights (for discussion of Phobos crater morphometry see Kokhanov et al., 2014). We also have compiled catalogs of lineaments, and boulders. In particular, we mapped 546 individual grooves or crater chains, which extend in length from 0.3 km to 16.2 km. We identified and determined the sizes and locations of 1379 boulders near crater Stickney. Cross-comparisons of gravity field models against distribution patterns of grooves and boulders are currently under way and may shed light on their possible origins. Finally, we have developed

  13. ECONOMIC COMPARABILITY OF INFORMATION SYSTEMS.

    DTIC Science & Technology

    not only on the probability distributions of channel in and outputs (events and messages) characterizing the information systems . This remains true when... information systems are interpreted as statistical experiments used to test hypotheses. Some pairs of information systems are, however, comparable...in the sense that one is preferable to another irrespective of the payoff function. There exists thus a partial ordering of information systems according

  14. Manufacturing information system

    NASA Astrophysics Data System (ADS)

    Allen, D. K.; Smith, P. R.; Smart, M. J.

    1983-12-01

    The size and cost of manufacturing equipment has made it extremely difficult to perform realistic modeling and simulation of the manufacturing process in university research laboratories. Likewise the size and cost factors, coupled with many uncontrolled variables of the production situation has even made it difficult to perform adequate manufacturing research in the industrial setting. Only the largest companies can afford manufacturing research laboratories; research results are often held proprietary and seldom find their way into the university classroom to aid in education and training of new manufacturing engineers. It is the purpose for this research to continue the development of miniature prototype equipment suitable for use in an integrated CAD/CAM Laboratory. The equipment being developed is capable of actually performing production operations (e.g. drilling, milling, turning, punching, etc.) on metallic and non-metallic workpieces. The integrated CAD/CAM Mini-Lab is integrating high resolution, computer graphics, parametric design, parametric N/C parts programmings, CNC machine control, automated storage and retrieval, with robotics materials handling. The availability of miniature CAD/CAM laboratory equipment will provide the basis for intensive laboratory research on manufacturing information systems.

  15. Applied Information Systems. Course Five. Information Systems Curriculum.

    ERIC Educational Resources Information Center

    O'Neil, Sharon Lund; Everett, Donna R.

    This course is the fifth of seven in the Information Systems curriculum. The purpose of the course is to build on skills acquired in the earlier courses. It reviews the importance of information to management and the organization and information systems concepts within an office. These components are provided for each task area: behavioral…

  16. The IAGOS Information System

    NASA Astrophysics Data System (ADS)

    Boulanger, D.; Thouret, V.

    2016-12-01

    IAGOS (In-service Aircraft for a Global Observing System) is a European Research Infrastructure which aims at the provision of long-term, regular and spatially resolved in situ observations of the atmospheric composition. IAGOS observation systems are deployed on a fleet of commercial aircraft and do measurements of aerosols, cloud particles, greenhouse gases, ozone, water vapor and nitrogen oxides from the surface to the lower stratosphere. The IAGOS database is an essential part of the global atmospheric monitoring network. It contains IAGOS-core and IAGOS-CARIBIC data. The IAGOS Data Portal (http://www.iagos.fr) is part of the French atmospheric chemistry data center AERIS (http://www.aeris-data.fr). In 2016 the new IAGOS Data Portal has been released. In addition to the data download the portal provides improved and new services such as download in NetCDF or NASA Ames formats and plotting tools (maps, time series, vertical profiles). New added value products are available through the portal: back trajectories, origin of air masses, co-location with satellite data. Web services allow to download IAGOS metadata such as flights and airports information. Administration tools have been implemented for users management and instruments monitoring. A major improvement is the interoperability with international portals and other databases in order to improve IAGOS data discovery. In the frame of the IGAS project (IAGOS for the Copernicus Atmospheric Service), a data network has been setup. It is composed of three data centers: the IAGOS database in Toulouse, the HALO research aircraft database at DLR (https://halo-db.pa.op.dlr.de) and the CAMS (Copernicus Atmosphere Monitoring Service) data center in Jülich (http://join.iek.fz-juelich.de). The link with the CAMS data center, through the JOIN interface, allows to combine model outputs with IAGOS data for inter-comparison. The CAMS project is a prominent user of the IGAS data network. Duting the next year IAGOS will

  17. The IAGOS Information System

    NASA Astrophysics Data System (ADS)

    Boulanger, Damien; Thouret, Valérie; Brissebrat, Guillaume

    2017-04-01

    IAGOS (In-service Aircraft for a Global Observing System) is a European Research Infrastructure which aims at the provision of long-term, regular and spatially resolved in situ observations of the atmospheric composition. IAGOS observation systems are deployed on a fleet of commercial aircraft and do measurements of aerosols, cloud particles, greenhouse gases, ozone, water vapor and nitrogen oxides from the surface to the lower stratosphere. The IAGOS database is an essential part of the global atmospheric monitoring network. It contains IAGOS-core data and IAGOS-CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) data. The IAGOS Data Portal http://www.iagos.org, damien.boulanger@obs-mip.fr) is part of the French atmospheric chemistry data center AERIS (http://www.aeris-data.fr). In 2016 the new IAGOS Data Portal has been released. In addition to the data download the portal provides improved and new services such as download in NetCDF or NASA Ames formats and plotting tools (maps, time series, vertical profiles, etc.). New added value products are or will be soon available through the portal: back trajectories, origin of air masses, co-location with satellite data, etc. Web services allow to download IAGOS metadata such as flights and airports information. Administration tools have been implemented for users management and instruments monitoring. A major improvement is the interoperability with international portals or other databases in order to improve IAGOS data discovery. In the frame of the IGAS project (IAGOS for the Copernicus Atmospheric Service), a data network has been setup. It is composed of three data centers: the IAGOS database in Toulouse, the HALO research aircraft database at DLR (https://halo-db.pa.op.dlr.de) and the CAMS (Copernicus Atmosphere Monitoring Service) data center in Jülich (http://join.iek.fz-juelich.de). The link with the CAMS data center, through the JOIN interface, allows to

  18. System status display information

    NASA Technical Reports Server (NTRS)

    Summers, L. G.; Erickson, J. B.

    1984-01-01

    The system Status Display is an electronic display system which provides the flight crew with enhanced capabilities for monitoring and managing aircraft systems. Guidelines for the design of the electronic system displays were established. The technical approach involved the application of a system engineering approach to the design of candidate displays and the evaluation of a Hernative concepts by part-task simulation. The system engineering and selection of candidate displays are covered.

  19. Strategic Planning and Information Systems.

    ERIC Educational Resources Information Center

    Shuman, Jack N.

    1982-01-01

    Discusses the functions of business planning systems and analyzes the underlying assumptions of the information systems that support strategic planning efforts within organizations. Development of a system framework, obstacles to the successful creation of strategic planning information systems, and resource allocation in organizations are…

  20. Integrating child health information systems.

    PubMed

    Hinman, Alan R; Eichwald, John; Linzer, Deborah; Saarlas, Kristin N

    2005-11-01

    The Health Resources and Services Administration and All Kids Count (a national technical assistance center fostering development of integrated child health information systems) have been working together to foster development of integrated child health information systems. Activities have included: identification of key elements for successful integration of systems; development of principles and core functions for the systems; a survey of state and local integration efforts; and a conference to develop a common vision for child health information systems to meet medical care and public health needs. We provide 1 state (Utah) as an example that is well on the way to development of integrated child health information systems.

  1. Integrating Child Health Information Systems

    PubMed Central

    Hinman, Alan R.; Eichwald, John; Linzer, Deborah; Saarlas, Kristin N.

    2005-01-01

    The Health Resources and Services Administration and All Kids Count (a national technical assistance center fostering development of integrated child health information systems) have been working together to foster development of integrated child health information systems. Activities have included: identification of key elements for successful integration of systems; development of principles and core functions for the systems; a survey of state and local integration efforts; and a conference to develop a common vision for child health information systems to meet medical care and public health needs. We provide 1 state (Utah) as an example that is well on the way to development of integrated child health information systems. PMID:16195524

  2. Genome-Wide Analysis of the Salmonella Fis Regulon and Its Regulatory Mechanism on Pathogenicity Islands

    PubMed Central

    Wang, Quan; Wang, Lei

    2013-01-01

    Fis, one of the most important nucleoid-associated proteins, functions as a global regulator of transcription in bacteria that has been comprehensively studied in Escherichia coli K12. Fis also influences the virulence of Salmonella enterica and pathogenic E. coli by regulating their virulence genes, however, the relevant mechanism is unclear. In this report, using combined RNA-seq and chromatin immunoprecipitation (ChIP)-seq technologies, we first identified 1646 Fis-regulated genes and 885 Fis-binding targets in the S. enterica serovar Typhimurium, and found a Fis regulon different from that in E. coli. Fis has been reported to contribute to the invasion ability of S. enterica. By using cell infection assays, we found it also enhances the intracellular replication ability of S. enterica within macrophage cell, which is of central importance for the pathogenesis of infections. Salmonella pathogenicity islands (SPI)-1 and SPI-2 are crucial for the invasion and survival of S. enterica in host cells. Using mutation and overexpression experiments, real-time PCR analysis, and electrophoretic mobility shift assays, we demonstrated that Fis regulates 63 of the 94 Salmonella pathogenicity island (SPI)-1 and SPI-2 genes, by three regulatory modes: i) binds to SPI regulators in the gene body or in upstream regions; ii) binds to SPI genes directly to mediate transcriptional activation of themselves and downstream genes; iii) binds to gene encoding OmpR which affects SPI gene expression by controlling SPI regulators SsrA and HilD. Our results provide new insights into the impact of Fis on SPI genes and the pathogenicity of S. enterica. PMID:23717649

  3. Information Systems Plan.

    DTIC Science & Technology

    1985-04-01

    calculation FREQUENCY THAT DATA SET IS USED: Variable - several times, several purposes CURRENT METHOD OF INFORMATION MANAGIMENT : Harris 500, stored on paper...INFORMATION MANAGIMENT : 0.2 FTE’s $9,400 A-85 29 CONDUCT PUBLIC AFFAIRS PROGRAM Conduct public affairs program by advising DE and staff on potential... Compensation Program) VINTAGE REQUIREMENT OF DATA SET: Variable DECISIONS OR PRODUCTS DATA SET SUPPORTS: FREQUENCY THAT DATA SET IS USED: Variable CURRENT

  4. Cockpit weather information system

    NASA Technical Reports Server (NTRS)

    Tu, Jeffrey Chen-Yu (Inventor)

    2000-01-01

    Weather information, periodically collected from throughout a global region, is periodically assimilated and compiled at a central source and sent via a high speed data link to a satellite communication service, such as COMSAT. That communication service converts the compiled weather information to GSDB format, and transmits the GSDB encoded information to an orbiting broadcast satellite, INMARSAT, transmitting the information at a data rate of no less than 10.5 kilobits per second. The INMARSAT satellite receives that data over its P-channel and rebroadcasts the GDSB encoded weather information, in the microwave L-band, throughout the global region at a rate of no less than 10.5 KB/S. The transmission is received aboard an aircraft by means of an onboard SATCOM receiver and the output is furnished to a weather information processor. A touch sensitive liquid crystal panel display allows the pilot to select the weather function by touching a predefined icon overlain on the display's surface and in response a color graphic display of the weather is displayed for the pilot.

  5. Fis1 deficiency selects for compensatory mutations responsible for cell death and growth control defects.

    PubMed

    Cheng, W-C; Teng, X; Park, H K; Tucker, C M; Dunham, M J; Hardwick, J M

    2008-12-01

    Genetic mutations affecting mitochondrial fission and fusion proteins cause human neurological disorders, but are assumed to be well tolerated in yeast. The conserved mitochondrial fission protein Dnm1/Drp1 is required for normal mitochondrial division, but also promotes cell death in mammals and yeast. Fis1, an outer mitochondrial membrane-anchored receptor for Dnm1/Drp1, also can promote cell death in mammals, but appears to have prosurvival activity in yeast. Here we report that deletion of the FIS1 gene in yeast consistently results in acquisition of a secondary mutation that confers sensitivity to cell death. In several independently derived FIS1 knockouts, tiling arrays and genomic sequencing identified the secondary mutation as a premature termination in the same stress-response gene, WHI2. The WHI2 mutation rescues the mitochondrial respiratory defect (petite formation) caused by FIS1 deficiency, but also causes a failure to suppress cell growth during amino-acid deprivation. Thus, loss of Fis1 drives the selection for specific compensatory mutations that confer defective growth control and cell death regulation, characteristic of human tumor cells. The important long-term survival function of Fis1 that is compensated by WHI2 mutation appears to be independent of fission factor Dnm1/Drp1 and its adaptor Mdv1, but may be mediated through a second adaptor Caf4, as WHI2 is also mutated in a CAF4 knockout.

  6. Fis1 deficiency selects for compensatory mutations responsible for cell death and growth control defects

    PubMed Central

    Cheng, W-C; Teng, X; Park, HK; Tucker, CM; Dunham, MJ; Hardwick, JM

    2008-01-01

    Genetic mutations affecting mitochondrial fission and fusion proteins cause human neurological disorders, but are assumed to be well tolerated in yeast. The conserved mitochondrial fission protein Dnm1/Drp1 is required for normal mitochondrial division, but also promotes cell death in mammals and yeast. Fis1, an outer mitochondrial membrane-anchored receptor for Dnm1/Drp1, also can promote cell death in mammals, but appears to have prosurvival activity in yeast. Here we report that deletion of the FIS1 gene in yeast consistently results in acquisition of a secondary mutation that confers sensitivity to cell death. In several independently derived FIS1 knockouts, tiling arrays and genomic sequencing identified the secondary mutation as a premature termination in the same stress-response gene, WHI2. The WHI2 mutation rescues the mitochondrial respiratory defect (petite formation) caused by FIS1 deficiency, but also causes a failure to suppress cell growth during amino-acid deprivation. Thus, loss of Fis1 drives the selection for specific compensatory mutations that confer defective growth control and cell death regulation, characteristic of human tumor cells. The important long-term survival function of Fis1 that is compensated by WHI2 mutation appears to be independent of fission factor Dnm1/Drp1 and its adaptor Mdv1, but may be mediated through a second adaptor Caf4, as WHI2 is also mutated in a CAF4 knockout. PMID:18756280

  7. Fis regulates the competitiveness of Pseudomonas putida on barley roots by inducing biofilm formation.

    PubMed

    Jakovleva, Julia; Teppo, Annika; Velts, Anna; Saumaa, Signe; Moor, Hanna; Kivisaar, Maia; Teras, Riho

    2012-03-01

    An important link between the environment and the physiological state of bacteria is the regulation of the transcription of a large number of genes by global transcription factors. One of the global regulators, Fis (factor for inversion stimulation), is well studied in Escherichia coli, but the role of this protein in pseudomonads has only been examined briefly. According to studies in Enterobacteriaceae, Fis regulates positively the flagellar movement of bacteria. In pseudomonads, flagellar movement is an important trait for the colonization of plant roots. Therefore we were interested in the role of the Fis protein in Pseudomonas putida, especially the possible regulation of the colonization of plant roots. We observed that Fis reduced the migration of P. putida onto the apices of barley roots and thereby the competitiveness of bacteria on the roots. Moreover, we observed that overexpression of Fis drastically reduced swimming motility and facilitated P. putida biofilm formation, which could be the reason for the decreased migration of bacteria onto the root apices. It is possible that the elevated expression of Fis is important in the adaptation of P. putida during colonization of plant roots by promoting biofilm formation when the migration of bacteria is no longer favoured.

  8. Toward intelligent information system

    NASA Astrophysics Data System (ADS)

    Komatsu, Sanzo

    NASA/RECON, the predecessor of DIALOG System, was originally designed as a user friendly system for astronauts, so that they should not miss-operate the machine in spite of tension in the outer space. Since then, DIALOG has endeavoured to develop a series of user friendly systems, such as knowledge index, inbound gateway, as well as Version II. In this so-called end user searching era, DIALOG has released a series of front end systems successively; DIALOG Business Connection, DIALOG Medical Connection and OneSearch in 1986, early and late 1987 respectively. They are all called expert systems. In this paper, the features of each system are described in some detail and the remaining critical issues are also discussed.

  9. Information Survivability Control Systems

    DTIC Science & Technology

    1999-01-01

    interfaces with higher-level (e.g., Federal Reserve ) and lower-level (e.g., branch) control systems. A hierarchical structure is natural to support...level hierarchical banking system with branch banks at the leaves, money-center banks in the middle, and the Federal Reserve system at the root...center in question, then the check deposit request is routed there. If not, then the check must be routed through the Federal Reserve . Checks for small

  10. The visual information system

    Treesearch

    Merlyn J. Paulson

    1979-01-01

    This paper outlines a project level process (V.I.S.) which utilizes very accurate and flexible computer algorithms in combination with contemporary site analysis and design techniques for visual evaluation, design and management. The process provides logical direction and connecting bridges through problem identification, information collection and verification, visual...

  11. Condition Assessment Information System

    SciTech Connect

    Rowe, Kenneth; McDermitt, Dennis

    2002-09-16

    CAIS2000 records, tracks and cost maintenance deficiencies associated with condition assessments of real property assets. Cost information is available for 39,000 items in the currenht RS Means, Facilities Construction Manual. These costs can, in turn, be rolled by by asset to produce the summary condition of an asset or site.

  12. Home Information Systems: A Primer.

    ERIC Educational Resources Information Center

    Moore, Robert C.

    The evolution of online home information systems, the nature and function of such systems, and their potential for wide-scale use are discussed in detail. Different types of home information systems, including one- and two-way interactive television, are described, and the unique technological features of the teletext, viewdata, and videotext…

  13. Newborn Screening Information System (NBSIS)

    PubMed Central

    Dayhoff, R. E.; Ledley, R. S.; Rotolo, L. S.

    1984-01-01

    A Newborn Screening Information System (NBSIS) has been developed to handle the information processing needs of State Newborn Screening Laboratories. Systems have been customized for use by the States of Maryland and Florida. These systems track clients (babies) from their first contact with the Screening Center through their last follow-up test, producing worksheets, result reports, letters, and summaries for archival storage.

  14. Forest Resource Information System

    NASA Technical Reports Server (NTRS)

    Mrocznyski, R. P.

    1983-01-01

    Twenty-three processing functions aid in utilizing LANDSAT data for forest resource management. Designed to work primarily with digital data obtained from measurements recorded by multispectral remote sensors mounted on aerospace platforms. communication between processing functions, simplicity of control, and commonality of data files in LARSFRIS enhance usefulness of system as tool for research and development of remote sensing systems.

  15. Global Land Information System (GLIS)

    USGS Publications Warehouse

    ,

    1992-01-01

    The Global Land Information System (GLIS) is an interactive computer system developed by the U.S. Geological Survey (USGS) for scientists seeking sources of information about the Earth's land surfaces. GLIS contains "metadata," that is, descriptive information about data sets. Through GLIS, scientists can evaluate data sets, determine their availability, and place online requests for products. GLIS is more, however, than a mere list of products. It offers online samples of earth science data that may be ordered through the system.

  16. Sensory Information Systems Program

    DTIC Science & Technology

    2012-03-06

    Measurement Scientific Challenge: How does binaural hearing disclose the locus of sound in real 3D environments? • Eliminates inter-aural...Auditory Representations. 22-23 August. Hosted by U. Washington. Informational Masking & Binaural Hearing. 17-19 Nov. Hosted by Boston U. Brain...representation and filtering. • E. Bleszynski (Monopole Research): Math model of bone- & tissue-conducted sound • M. Elhilali (Johns Hopkins U

  17. Science information systems: Visualization

    NASA Technical Reports Server (NTRS)

    Wall, Ray J.

    1991-01-01

    Future programs in earth science, planetary science, and astrophysics will involve complex instruments that produce data at unprecedented rates and volumes. Current methods for data display, exploration, and discovery are inadequate. Visualization technology offers a means for the user to comprehend, explore, and examine complex data sets. The goal of this program is to increase the effectiveness and efficiency of scientists in extracting scientific information from large volumes of instrument data.

  18. Information Systems Administration. Course Seven. Information Systems Curriculum.

    ERIC Educational Resources Information Center

    O'Neil, Sharon Lund; Everett, Donna R.

    This course is the seventh of seven in the Information Systems curriculum. The purpose of this capstone course is to build on skills acquired in the earlier courses. Emphasis is placed on realistic situations and challenges that exist in the automated office and for which information systems technology and skills are pertinent. These components…

  19. Implementing Student Information Systems

    ERIC Educational Resources Information Center

    Sullivan, Laurie; Porter, Rebecca

    2006-01-01

    Implementing an enterprise resource planning system is a complex undertaking. Careful planning, management, communication, and staffing can make the difference between a successful and unsuccessful implementation. (Contains 3 tables.)

  20. Forest resource information system

    NASA Technical Reports Server (NTRS)

    Mroczynski, R. P. (Principal Investigator)

    1978-01-01

    The author has identified the following significant results. A benchmark classification evaluation framework was implemented. The FRIS preprocessing activities were refined. Potential geo-based referencing systems were identified as components of FRIS.

  1. Implementing Student Information Systems

    ERIC Educational Resources Information Center

    Sullivan, Laurie; Porter, Rebecca

    2006-01-01

    Implementing an enterprise resource planning system is a complex undertaking. Careful planning, management, communication, and staffing can make the difference between a successful and unsuccessful implementation. (Contains 3 tables.)

  2. Medical Information Management System (MIMS): A generalized interactive information system

    NASA Technical Reports Server (NTRS)

    Alterescu, S.; Friedman, C. A.; Hipkins, K. R.

    1975-01-01

    An interactive information system is described. It is a general purpose, free format system which offers immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. Examples of the system's operation, commentary on the examples, and a complete listing of the system program are included.

  3. Medical Information Management System (MIMS): An automated hospital information system

    NASA Technical Reports Server (NTRS)

    Alterescu, S.; Simmons, P. B.; Schwartz, R. A.

    1971-01-01

    An automated hospital information system that handles all data related to patient-care activities is described. The description is designed to serve as a manual for potential users, nontechnical medical personnel who may use the system. Examples of the system's operation, commentary on the examples, and a complete listing of the system program are included.

  4. Geographic names information system

    USGS Publications Warehouse

    ,

    1987-01-01

    of the data in each of the data elements of the four data bases of GNIS. The GNIS program, which includes the automated names system and the National Gazetteer program, is a coordinated effort under the direction of Donald J. Orth, Chief of the Branch of Geographic Names. The automated system was initially developed by Sam Stulberg and Roger L. Payne. System enhancement and software development is coordinated by Judy J. Stella, head programmer for GNIS, and special projects coordinator is Louis A. Yost IV. Coordination of the research and compilation of certain gazetteers is directed by Robin D. Worcester with research assistance and support from Jon Campbell, Linda S. Davis, and Nancy Engel.

  5. The Fire Effects Information System

    Treesearch

    William C. Fischer

    1987-01-01

    Lack of information regarding fire effects is perceived by many fire and resource managers as a barrier to the effective application of prescribed fire. This lack of information, in many instances, is the result of poor diffusion of existing knowledge rather than lack of knowledge. A computerized Fire Effects Information System can make existing fire effects knowledge...

  6. Information technology equipment cooling system

    DOEpatents

    Schultz, Mark D.

    2014-06-10

    According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment.

  7. On Selecting Commercial Information Systems

    PubMed Central

    Möhr, J.R.; Sawinski, R.; Kluge, A.; Alle, W.

    1984-01-01

    As more commercial information systems become available, the methodology for their selection gains importance. An instances where the method employed for the selection of laboratory information systems was multilevel assessment. The method is described and the experience gained in the project is summarized and discussed. Evidence is provided that the employed method is comprehensive, reproducible, valid and economic.

  8. Tropical Cyclone Information System

    NASA Technical Reports Server (NTRS)

    Li, P. Peggy; Knosp, Brian W.; Vu, Quoc A.; Yi, Chao; Hristova-Veleva, Svetla M.

    2009-01-01

    The JPL Tropical Cyclone Infor ma tion System (TCIS) is a Web portal (http://tropicalcyclone.jpl.nasa.gov) that provides researchers with an extensive set of observed hurricane parameters together with large-scale and convection resolving model outputs. It provides a comprehensive set of high-resolution satellite (see figure), airborne, and in-situ observations in both image and data formats. Large-scale datasets depict the surrounding environmental parameters such as SST (Sea Surface Temperature) and aerosol loading. Model outputs and analysis tools are provided to evaluate model performance and compare observations from different platforms. The system pertains to the thermodynamic and microphysical structure of the storm, the air-sea interaction processes, and the larger-scale environment as depicted by ocean heat content and the aerosol loading of the environment. Currently, the TCIS is populated with satellite observations of all tropical cyclones observed globally during 2005. There is a plan to extend the database both forward in time till present as well as backward to 1998. The portal is powered by a MySQL database and an Apache/Tomcat Web server on a Linux system. The interactive graphic user interface is provided by Google Map.

  9. Medical-Information-Management System

    NASA Technical Reports Server (NTRS)

    Alterescu, Sidney; Friedman, Carl A.; Frankowski, James W.

    1989-01-01

    Medical Information Management System (MIMS) computer program interactive, general-purpose software system for storage and retrieval of information. Offers immediate assistance where manipulation of large data bases required. User quickly and efficiently extracts, displays, and analyzes data. Used in management of medical data and handling all aspects of data related to care of patients. Other applications include management of data on occupational safety in public and private sectors, handling judicial information, systemizing purchasing and procurement systems, and analyses of cost structures of organizations. Written in Microsoft FORTRAN 77.

  10. Medical-Information-Management System

    NASA Technical Reports Server (NTRS)

    Alterescu, Sidney; Friedman, Carl A.; Frankowski, James W.

    1989-01-01

    Medical Information Management System (MIMS) computer program interactive, general-purpose software system for storage and retrieval of information. Offers immediate assistance where manipulation of large data bases required. User quickly and efficiently extracts, displays, and analyzes data. Used in management of medical data and handling all aspects of data related to care of patients. Other applications include management of data on occupational safety in public and private sectors, handling judicial information, systemizing purchasing and procurement systems, and analyses of cost structures of organizations. Written in Microsoft FORTRAN 77.

  11. The IAGOS information system

    NASA Astrophysics Data System (ADS)

    Boulanger, Damien; Gautron, Benoit; Schultz, Martin; Brötz, Björn; Rauthe-Schöch, Armin; Thouret, Valérie

    2015-04-01

    IAGOS (In-service Aircraft for a Global Observing System) aims at the provision of long-term, frequent, regular, accurate, and spatially resolved in situ observations of the atmospheric composition. IAGOS observation systems are deployed on a fleet of commercial aircraft. The IAGOS database is an essential part of the global atmospheric monitoring network. Data access is handled by open access policy based on the submission of research requests which are reviewed by the PIs. The IAGOS database (http://www.iagos.fr, damien.boulanger@obs-mip.fr) is part of the French atmospheric chemistry data centre Ether (CNES and CNRS). In the framework of the IGAS project (IAGOS for Copernicus Atmospheric Service) interoperability with international portals or other databases is implemented in order to improve IAGOS data discovery. The IGAS data network is composed of three data centres: the IAGOS database in Toulouse including IAGOS-core data and IAGOS-CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) data since January 2015; the HALO research aircraft database at DLR (https://halo-db.pa.op.dlr.de); and the MACC data centre in Jülich (http://join.iek.fz-juelich.de). The MACC (Monitoring Atmospheric Composition and Climate) project is a prominent user of the IGAS data network. In June 2015 a new version of the IAGOS database will be released providing improved services such as download in NetCDF or NASA Ames formats; graphical tools (maps, scatter plots, etc.); standardized metadata (ISO 19115) and a better users management. The link with the MACC data centre, through JOIN (Jülich OWS Interface), will allow to combine model outputs with IAGOS data for intercomparison. The interoperability within the IGAS data network, implemented thanks to many web services, will improve the functionalities of the web interfaces of each data centre.

  12. NASA space information systems overview

    NASA Technical Reports Server (NTRS)

    Hall, Dana L.

    1987-01-01

    A major objective of NASA space missions is the gathering of information that when analyzed, compared, and interpreted furthers man's knowledge of his planet and surrounding universe. A space information system is the combination of data gathering, data processing, and data transport capabilities that interact to provide the underlying services that enable that advancement in understanding. Past space projects have been characterized by rather disjoint data systems that often did not satisfy user requirements. NASA has learned from those experiences, however, and now is conceptualizing a new generation of sophisticated, integrated space information systems suitable to the wide range of near future space endeavors. This paper examines the characteristics of recent data systems and, based upon that characterization, outlines the scope and attributes of future systems. A description if offered of the information system for the Space Station Program as one real example of such advanced capabilities.

  13. Biochemical identification of base and phosphate contacts between Fis and a high affinity DNA binding site

    PubMed Central

    Shao, Yongping; Feldman-Cohen, Leah S.; Osuna, Robert

    2008-01-01

    SUMMARY Fis is a nucleoid-associated protein in E. coli and other bacteria that stimulates certain site-specific DNA recombination events, alters DNA topology, and serves as a global gene regulator. DNA binding is central to the functions of Fis and involves a helix-turn-helix DNA binding motif located in the carboxy-terminal region. Specific DNA binding is observed at a number of sites exhibiting poorly related sequences. Such interactions require four critical base pairs positioned −7, −3, +3, and +7 nucleotides relative to the central nucleotide of a 15 bp core-binding site. To further understand how Fis interacts with DNA, we identified the positions of fourteen DNA phosphates (based on ethylation interference assays) that are required for Fis binding. These are the 5’ phosphates of the nucleotides at positions −8, −7, −6, +1, +2, +3, and +4 relative to the central nucleotide on both DNA strands. Another five phosphates located in the flanking regions from positions +10 through +14 can serve as additional contact sites. Using a combination of biochemical approaches and various mutant Fis proteins, we probed possible interactions between several key Fis residues and DNA bases or phosphates within a high-affinity binding site. We provide evidence in support of interactions between the R85 Fis residue and a highly conserved guanine at position −7, and between T87 and the critical base pairs at −3 and +3. In addition, we present evidence in support of interactions between N84 and the phosphate 5’ to the base at +4, between R89 and the −7 phosphate, between T87 and the +3 and +4 phosphates, and between K90 and the +3 phosphate. This work provides functional evidence for some of the most critical interactions between Fis and DNA required for a high binding affinity and demonstrates the large contribution made by numerous phosphates to the stability of the Fis-DNA complex. PMID:18514225

  14. Integrated risk information system (IRIS)

    SciTech Connect

    Tuxen, L.

    1990-12-31

    The Integrated Risk Information System (IRIS) is an electronic information system developed by the US Environmental Protection Agency (EPA) containing information related to health risk assessment. IRIS is the Agency`s primary vehicle for communication of chronic health hazard information that represents Agency consensus following comprehensive review by intra-Agency work groups. The original purpose for developing IRIS was to provide guidance to EPA personnel in making risk management decisions. This original purpose for developing IRIS was to guidance to EPA personnel in making risk management decisions. This role has expanded and evolved with wider access and use of the system. IRIS contains chemical-specific information in summary format for approximately 500 chemicals. IRIS is available to the general public on the National Library of Medicine`s Toxicology Data Network (TOXNET) and on diskettes through the National Technical Information Service (NTIS).

  15. Multipurpose interactive NASA information system

    NASA Technical Reports Server (NTRS)

    Hill, J. M.; Keefer, R. L.; Sanders, D. R.; Seitz, R. N.

    1979-01-01

    Multipurpose Interactive NASA Information System (MINIS) is data management system capable of retrieving descriptive data from LANDSAT photos. General enough to be used with other user-defined data bases, interactive data management and information retrieval system was especially developed for small and medium-sized computers. It uses free-form data base that allows one to create entirely new and different data bases and to control format of output products.

  16. Developing Information Systems for Competitive Intelligence Support.

    ERIC Educational Resources Information Center

    Hohhof, Bonnie

    1994-01-01

    Discusses issues connected with developing information systems for competitive intelligence support; defines the elements of an effective competitive information system; and summarizes issues affecting system design and implementation. Highlights include intelligence information; information needs; information sources; decision making; and…

  17. Earth Science Information System (ESIS)

    USGS Publications Warehouse

    ,

    1982-01-01

    The Earth Science Information System (ESIS) was developed in 1981 by the U.S. Geological Survey's Office of the Data Administrator. ESIS serves as a comprehensive data management facility designed to support the coordination, integration, and standardization of scientific, technical, and bibliographic data of the U.S. Geological Survey (USGS). ESIS provides, through an online interactive computer system, referral to information about USGS data bases, data elements which are fields in the records of data bases, and systems. The data bases contain information about many subjects from several scientific disciplines such as: geology, geophysics, geochemistry, hydrology, cartography, oceanography, geography, minerals exploration and conservation, and satellite data sensing.

  18. Information Requirements for a Procurement Management Information System.

    DTIC Science & Technology

    1975-08-01

    Management Information System is...described and some justification for this type of procurement management information system is presented. A literature search was made to determine...information systems. If information requirements are correctly identified and satisfied by a procurement management information system , contract administration and procurement management can be

  19. Computerized international geothermal information systems

    SciTech Connect

    Phillips, S.L.; Lawrence, J.D.; Lepman, S.R.

    1980-03-01

    The computerized international geothermal energy information system is reviewed. The review covers establishment of the Italy - United States linked data centers by the NATO Committee on Challenges of Modern Society, through a bilateral agreement, and up to the present time. The result of the information exchange project is given as the bibliographic and numerical data available from the data centers. Recommendations for the exchange of computerized geothermal information at the international level are discussed.

  20. Medical Information Management System (MIMS): A Generalized Interactive Information System.

    ERIC Educational Resources Information Center

    Alterescu,Sidney; And Others

    This report describes an interactive information system. It is a general purpose, free format system which can offer immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. The report is designed to serve as a manual for potential users--nontechnical personnel who will use the…

  1. Competencies for Information Systems Workers.

    ERIC Educational Resources Information Center

    Everett, Donna R.; O'Neil, Sharon Lund

    1990-01-01

    Through survey research using the DACUM approach and the Delphi technique, 8 broad skill categories and 278 competencies were determined to have some degree of importance for information systems workers. (Author)

  2. System Wide Information Management (SWIM)

    NASA Technical Reports Server (NTRS)

    Hritz, Mike; McGowan, Shirley; Ramos, Cal

    2004-01-01

    This viewgraph presentation lists questions regarding the implementation of System Wide Information Management (SWIM). Some of the questions concern policy issues and strategies, technology issues and strategies, or transition issues and strategies.

  3. Integrated Compliance Information System (ICIS)

    EPA Pesticide Factsheets

    The purpose of ICIS is to meet evolving Enforcement and Compliance business needs for EPA and State users by integrating information into a single integrated data system that supports both management and programmatic requirements of the Enforcement and Compliance programs.

  4. Maryland Automated Geographic Information System

    NASA Technical Reports Server (NTRS)

    Thomas, E. L.

    1978-01-01

    A computer based system designed for storing geographic data in a consistent and coordinated manner is described. The data are stored, retrieved, and analyzed using a 400 km sq/acre cell. Stored information can be displayed on computer maps in a manner similar to standard map graphics. The data bank contains various information for performing land use analysis in a variety of areas.

  5. Maryland Automated Geographic Information System

    NASA Technical Reports Server (NTRS)

    Thomas, E. L.

    1978-01-01

    A computer based system designed for storing geographic data in a consistent and coordinated manner is described. The data are stored, retrieved, and analyzed using a 400 km sq/acre cell. Stored information can be displayed on computer maps in a manner similar to standard map graphics. The data bank contains various information for performing land use analysis in a variety of areas.

  6. Pesticide Product Information System (PPIS)

    EPA Pesticide Factsheets

    The Pesticide Product Information System contains information concerning all pesticide products registered in the United States. It includes registrant name and address, chemical ingredients, toxicity category, product names, distributor brand names, site/pest uses, pesticidal type, formulation code, and registration status.

  7. RIMS: Resource Information Management System

    NASA Technical Reports Server (NTRS)

    Symes, J.

    1983-01-01

    An overview is given of the capabilities and functions of the resource management system (RIMS). It is a simple interactive DMS tool which allows users to build, modify, and maintain data management applications. The RIMS minimizes programmer support required to develop/maintain small data base applications. The RIMS also assists in bringing the United Information Services (UIS) budget system work inhouse. Information is also given on the relationship between the RIMS and the user community.

  8. Geographic Information System Data Analysis

    NASA Technical Reports Server (NTRS)

    Billings, Chad; Casad, Christopher; Floriano, Luis G.; Hill, Tracie; Johnson, Rashida K.; Locklear, J. Mark; Penn, Stephen; Rhoulac, Tori; Shay, Adam H.; Taylor, Antone; hide

    1995-01-01

    Data was collected in order to further NASA Langley Research Center's Geographic Information System(GIS). Information on LaRC's communication, electrical, and facility configurations was collected. Existing data was corrected through verification, resulting in more accurate databases. In addition, Global Positioning System(GPS) points were used in order to accurately impose buildings on digitized images. Overall, this project will help the Imaging and CADD Technology Team (ICTT) prove GIS to be a valuable resource for LaRC.

  9. RIMS: Resource Information Management System

    NASA Technical Reports Server (NTRS)

    Symes, J.

    1983-01-01

    An overview is given of the capabilities and functions of the resource management system (RIMS). It is a simple interactive DMS tool which allows users to build, modify, and maintain data management applications. The RIMS minimizes programmer support required to develop/maintain small data base applications. The RIMS also assists in bringing the United Information Services (UIS) budget system work inhouse. Information is also given on the relationship between the RIMS and the user community.

  10. ROMANSE Public Transport Information Systems

    NASA Astrophysics Data System (ADS)

    Brown, Steven

    ROMANSE is multi-million pound pilot project based in Southampton. It aims to use Advanced Transport Telematics (ATT) to develop the city as a model for transport management systems across Europe. ROMANSE achieves this by providing realtime traffic and travel information to influence travel behaviour, increase the use of public transport, maximize the efficiency of the transport system and provide high-quality information for use in strategic policy decisions.

  11. DNA sequence determinants controlling affinity, stability and shape of DNA complexes bound by the nucleoid protein Fis

    DOE PAGES

    Hancock, Stephen P.; Stella, Stefano; Cascio, Duilio; ...

    2016-03-09

    The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA backbone contacts and selects target sites by reading conformational properties of DNA sequences, most prominently intrinsic minor groove widths. High-affinity binding requires Fis-stabilized DNA conformational changes that vary depending on DNA sequence. In order to better understand the molecular basis for high affinity site recognition, we analyzed the effects of DNA sequence within and flanking the core Fis binding site on binding affinity and DNA structure. X-ray crystal structures of Fis-DNA complexes containing variable sequencesmore » in the noncontacted center of the binding site or variations within the major groove interfaces show that the DNA can adapt to the Fis dimer surface asymmetrically. We show that the presence and position of pyrimidine-purine base steps within the major groove interfaces affect both local DNA bending and minor groove compression to modulate affinities and lifetimes of Fis-DNA complexes. Sequences flanking the core binding site also modulate complex affinities, lifetimes, and the degree of local and global Fis-induced DNA bending. In particular, a G immediately upstream of the 15 bp core sequence inhibits binding and bending, and A-tracts within the flanking base pairs increase both complex lifetimes and global DNA curvatures. Taken together, our observations support a revised DNA motif specifying high-affinity Fis binding and highlight the range of conformations that Fis-bound DNA can adopt. Lastly, the affinities and DNA conformations of individual Fis-DNA complexes are likely to be tailored to their context-specific biological functions.« less

  12. DNA sequence determinants controlling affinity, stability and shape of DNA complexes bound by the nucleoid protein Fis

    SciTech Connect

    Hancock, Stephen P.; Stella, Stefano; Cascio, Duilio; Johnson, Reid C.; Leng, Fenfei

    2016-03-09

    The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA backbone contacts and selects target sites by reading conformational properties of DNA sequences, most prominently intrinsic minor groove widths. High-affinity binding requires Fis-stabilized DNA conformational changes that vary depending on DNA sequence. In order to better understand the molecular basis for high affinity site recognition, we analyzed the effects of DNA sequence within and flanking the core Fis binding site on binding affinity and DNA structure. X-ray crystal structures of Fis-DNA complexes containing variable sequences in the noncontacted center of the binding site or variations within the major groove interfaces show that the DNA can adapt to the Fis dimer surface asymmetrically. We show that the presence and position of pyrimidine-purine base steps within the major groove interfaces affect both local DNA bending and minor groove compression to modulate affinities and lifetimes of Fis-DNA complexes. Sequences flanking the core binding site also modulate complex affinities, lifetimes, and the degree of local and global Fis-induced DNA bending. In particular, a G immediately upstream of the 15 bp core sequence inhibits binding and bending, and A-tracts within the flanking base pairs increase both complex lifetimes and global DNA curvatures. Taken together, our observations support a revised DNA motif specifying high-affinity Fis binding and highlight the range of conformations that Fis-bound DNA can adopt. Lastly, the affinities and DNA conformations of individual Fis-DNA complexes are likely to be tailored to their context-specific biological functions.

  13. Site selection for managed aquifer recharge using fuzzy rules: integrating geographical information system (GIS) tools and multi-criteria decision making

    NASA Astrophysics Data System (ADS)

    Malekmohammadi, Bahram; Ramezani Mehrian, Majid; Jafari, Hamid Reza

    2012-11-01

    One of the most important water-resources management strategies for arid lands is managed aquifer recharge (MAR). In establishing a MAR scheme, site selection is the prime prerequisite that can be assisted by geographic information system (GIS) tools. One of the most important uncertainties in the site-selection process using GIS is finite ranges or intervals resulting from data classification. In order to reduce these uncertainties, a novel method has been developed involving the integration of multi-criteria decision making (MCDM), GIS, and a fuzzy inference system (FIS). The Shemil-Ashkara plain in the Hormozgan Province of Iran was selected as the case study; slope, geology, groundwater depth, potential for runoff, land use, and groundwater electrical conductivity have been considered as site-selection factors. By defining fuzzy membership functions for the input layers and the output layer, and by constructing fuzzy rules, a FIS has been developed. Comparison of the results produced by the proposed method and the traditional simple additive weighted (SAW) method shows that the proposed method yields more precise results. In conclusion, fuzzy-set theory can be an effective method to overcome associated uncertainties in classification of geographic information data.

  14. Information Processing in Living Systems

    NASA Astrophysics Data System (ADS)

    Tkačik, Gašper; Bialek, William

    2016-03-01

    Life depends as much on the flow of information as on the flow of energy. Here we review the many efforts to make this intuition precise. Starting with the building blocks of information theory, we explore examples where it has been possible to measure, directly, the flow of information in biological networks, or more generally where information-theoretic ideas have been used to guide the analysis of experiments. Systems of interest range from single molecules (the sequence diversity in families of proteins) to groups of organisms (the distribution of velocities in flocks of birds), and all scales in between. Many of these analyses are motivated by the idea that biological systems may have evolved to optimize the gathering and representation of information, and we review the experimental evidence for this optimization, again across a wide range of scales.

  15. Safeguards Information Management Systems (SIMS)

    SciTech Connect

    Sorenson, R.J.; Sheely, K.B.; Brown, J.B.; Horton, R.D.; Strittmatter, R.; Manatt, D.R.

    1994-04-01

    The requirements for the management of information at the International Atomic Energy Agency (IAEA) and its Department of Safeguards are rapidly changing. Historically, the Department of Safeguards has had the requirement to process large volumes of conventional safeguards information. An information management system is currently in place that adequately handles the IAEA`s conventional safeguards data needs. In the post-Iraq environment, however, there is a growing need to expand the IAEA information management capability to include unconventional forms of information. These data include environmental sampling results, photographs, video film, lists of machine tools, and open-source materials such as unclassified publications. The US Department of Energy (DOE) has responded to this information management need by implementing the Safeguards Information Management Systems (SIMS) initiative. SIMS was created by the DOE to anticipate and respond to IAEA information management needs through a multilaboratory initiative that will utilize an integrated approach to develop and deploy technology in a timely and cost-effective manner. The DOE will use the SIMS initiative to coordinate US information management activities that support the IAEA Department of Safeguards.

  16. MIMS - MEDICAL INFORMATION MANAGEMENT SYSTEM

    NASA Technical Reports Server (NTRS)

    Frankowski, J. W.

    1994-01-01

    MIMS, Medical Information Management System is an interactive, general purpose information storage and retrieval system. It was first designed to be used in medical data management, and can be used to handle all aspects of data related to patient care. Other areas of application for MIMS include: managing occupational safety data in the public and private sectors; handling judicial information where speed and accuracy are high priorities; systemizing purchasing and procurement systems; and analyzing organizational cost structures. Because of its free format design, MIMS can offer immediate assistance where manipulation of large data bases is required. File structures, data categories, field lengths and formats, including alphabetic and/or numeric, are all user defined. The user can quickly and efficiently extract, display, and analyze the data. Three means of extracting data are provided: certain short items of information, such as social security numbers, can be used to uniquely identify each record for quick access; records can be selected which match conditions defined by the user; and specific categories of data can be selected. Data may be displayed and analyzed in several ways which include: generating tabular information assembled from comparison of all the records on the system; generating statistical information on numeric data such as means, standard deviations and standard errors; and displaying formatted listings of output data. The MIMS program is written in Microsoft FORTRAN-77. It was designed to operate on IBM Personal Computers and compatibles running under PC or MS DOS 2.00 or higher. MIMS was developed in 1987.

  17. MIMS - MEDICAL INFORMATION MANAGEMENT SYSTEM

    NASA Technical Reports Server (NTRS)

    Frankowski, J. W.

    1994-01-01

    MIMS, Medical Information Management System is an interactive, general purpose information storage and retrieval system. It was first designed to be used in medical data management, and can be used to handle all aspects of data related to patient care. Other areas of application for MIMS include: managing occupational safety data in the public and private sectors; handling judicial information where speed and accuracy are high priorities; systemizing purchasing and procurement systems; and analyzing organizational cost structures. Because of its free format design, MIMS can offer immediate assistance where manipulation of large data bases is required. File structures, data categories, field lengths and formats, including alphabetic and/or numeric, are all user defined. The user can quickly and efficiently extract, display, and analyze the data. Three means of extracting data are provided: certain short items of information, such as social security numbers, can be used to uniquely identify each record for quick access; records can be selected which match conditions defined by the user; and specific categories of data can be selected. Data may be displayed and analyzed in several ways which include: generating tabular information assembled from comparison of all the records on the system; generating statistical information on numeric data such as means, standard deviations and standard errors; and displaying formatted listings of output data. The MIMS program is written in Microsoft FORTRAN-77. It was designed to operate on IBM Personal Computers and compatibles running under PC or MS DOS 2.00 or higher. MIMS was developed in 1987.

  18. National Information Systems Security (INFOSEC) Glossary

    DTIC Science & Technology

    2000-09-01

    Systems Security Engineering ISSM Information Systems Security Manager ISSO Information Systems Security Officer IT Information Technology ITAR ...Digital Net Radio Interface Unit SDNS Secure Data Network System SDR System Design Review SFA Security Fault Analysis SHA Secure Hash Algorithm

  19. Ecological Monitoring Information System (EMIS).

    ERIC Educational Resources Information Center

    Fiene, Richard John; And Others

    A system for evaluating and monitoring child development projects, with possible computerization capabilities, was developed for the State of Pennsylvania in connection with 26 child development projects funded by the Appalachian Regional Commission. The Ecological Monitoring Information System (EMIS), provides a series of ecological measurement…

  20. Simulating The SSF Information System

    NASA Technical Reports Server (NTRS)

    Deshpande, Govind K.; Kleine, Henry; Younger, Joseph C.; Sanders, Felicia A.; Smith, Jeffrey L.; Aster, Robert W.; Olivieri, Jerry M.; Paul, Lori L.

    1993-01-01

    Freedom Operations Simulation Test (FROST) computer program simulates operation of SSF information system, tracking every packet of data from generation to destination, for both uplinks and downlinks. Collects various statistics concerning operation of system and provides reports of statistics at intervals specified by user. FROST also incorporates graphical-display capability to enhance interpretation of these statistics. Written in SIMSCRIPT 11.5.

  1. Simulating The SSF Information System

    NASA Technical Reports Server (NTRS)

    Deshpande, Govind K.; Kleine, Henry; Younger, Joseph C.; Sanders, Felicia A.; Smith, Jeffrey L.; Aster, Robert W.; Olivieri, Jerry M.; Paul, Lori L.

    1993-01-01

    Freedom Operations Simulation Test (FROST) computer program simulates operation of SSF information system, tracking every packet of data from generation to destination, for both uplinks and downlinks. Collects various statistics concerning operation of system and provides reports of statistics at intervals specified by user. FROST also incorporates graphical-display capability to enhance interpretation of these statistics. Written in SIMSCRIPT 11.5.

  2. The Work Unit Information System

    DTIC Science & Technology

    1990-03-01

    be discussing the current WUIS documentation, the various data input systems that currently exist, the current makeup of the database, and the various...corrections be submitted at least once a year for all active work units. 5 5. SIZE AND MAKEUP OF WUIS DATABASE The Work Unit Information System

  3. Reasonable Accommodation Information Tracking System

    EPA Pesticide Factsheets

    The Reasonable Accommodation Information Tracking System (RAITS) is a case management system that allows the National Reasonable Accommodation Coordinator (NRAC) and the Local Reasonable Accommodation Coordinators (LORAC) to manage information related to Reasonable Accommodation (RA) requests. It provides a data base system in compliance with Executive Order 13164 and required by the Equal Employment Opportunity Commission (EEOC) Regulations and American Federation of Government Employees (AFGE) Bargaining Unit as described in the AFGE National Reasonable Accommodation Procedures. It is a tool that was internally developed in Lotus Notes to track requests for reasonable accommodation and was custom-configured to meet EPA's specific needs and infrastructure.

  4. A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission.

    PubMed

    Koppenol-Raab, Marijke; Harwig, Megan Cleland; Posey, Ammon E; Egner, John M; MacKenzie, Kevin R; Hill, R Blake

    2016-09-23

    The tail-anchored protein Fis1 is implicated as a passive tether in yeast mitochondrial fission. We probed the functional role of Fis1 Glu-78, whose elevated side chain pKa suggests participation in protein interactions. Fis1 binds partners Mdv1 or Dnm1 tightly, but mutation E78A weakens Fis1 interaction with Mdv1, alters mitochondrial morphology, and abolishes fission in a growth assay. In fis1Δ rescue experiments, Fis1-E78A causes a novel localization pattern in which Dnm1 uniformly coats the mitochondria. By contrast, Fis1-E78A at lower expression levels recruits Dnm1 into mitochondrial punctate structures but fails to support normal fission. Thus, Fis1 makes multiple interactions that support Dnm1 puncta formation and may be essential after this step, supporting a revised model for assembly of the mitochondrial fission machinery. The insights gained by mutating a residue with a perturbed pKa suggest that side chain pKa values inferred from routine NMR sample pH optimization could provide useful leads for functional investigations. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  5. A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission*

    PubMed Central

    Koppenol-Raab, Marijke; Harwig, Megan Cleland; Posey, Ammon E.; Egner, John M.; MacKenzie, Kevin R.; Hill, R. Blake

    2016-01-01

    The tail-anchored protein Fis1 is implicated as a passive tether in yeast mitochondrial fission. We probed the functional role of Fis1 Glu-78, whose elevated side chain pKa suggests participation in protein interactions. Fis1 binds partners Mdv1 or Dnm1 tightly, but mutation E78A weakens Fis1 interaction with Mdv1, alters mitochondrial morphology, and abolishes fission in a growth assay. In fis1Δ rescue experiments, Fis1-E78A causes a novel localization pattern in which Dnm1 uniformly coats the mitochondria. By contrast, Fis1-E78A at lower expression levels recruits Dnm1 into mitochondrial punctate structures but fails to support normal fission. Thus, Fis1 makes multiple interactions that support Dnm1 puncta formation and may be essential after this step, supporting a revised model for assembly of the mitochondrial fission machinery. The insights gained by mutating a residue with a perturbed pKa suggest that side chain pKa values inferred from routine NMR sample pH optimization could provide useful leads for functional investigations. PMID:27496949

  6. Forest Resource Information System (FRIS)

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The technological and economical feasibility of using multispectral digital image data as acquired from the LANDSAT satellites in an ongoing operational forest information system was evaluated. Computer compatible multispectral scanner data secured from the LANDSAT satellites were demonstrated to be a significant contributor to ongoing information systems by providing the added dimensions of synoptic and repeat coverage of the Earth's surface. Major forest cover types of conifer, deciduous, mixed conifer-deciduous and non-forest, were classified well within the bounds of the statistical accuracy of the ground sample. Further, when overlayed with existing maps, the acreage of cover type retains a high level of positional integrity. Maps were digitized by a graphics design system, overlayed and registered onto LANDSAT imagery such that the map data with associated attributes were displayed on the image. Once classified, the analysis results were converted back to map form as a cover type of information. Existing tabular information as represented by inventory is registered geographically to the map base through a vendor provided data management system. The notion of a geographical reference base (map) providing the framework to which imagery and tabular data bases are registered and where each of the three functions of imagery, maps and inventory can be accessed singly or in combination is the very essence of the forest resource information system design.

  7. Evolution of toxicology information systems

    SciTech Connect

    Wassom, J.S.; Lu, P.Y.

    1990-12-31

    Society today is faced with new health risk situations that have been brought about by recent scientific and technical advances. Federal and state governments are required to assess the many potential health risks to exposed populations from the products (chemicals) and by-products (pollutants) of these advances. Because a sound analysis of any potential health risk should be based on the use of relevant information, it behooves those individuals responsible for making the risk assessments to know where to obtain needed information. This paper reviews the origins of toxicology information systems and explores the specialized information center concept that was proposed in 1963 as a means of providing ready access to scientific and technical information. As a means of illustrating this concept, the operation of one specialized information center (the Environmental Mutagen Information Center at Oak Ridge National Laboratory) will be discussed. Insights into how toxicological information resources came into being, their design and makeup, will be of value to those seeking to acquire information for risk assessment purposes. 7 refs., 1 fig., 4 tabs.

  8. Using Innovative Information Systems Techniques To Teach Information Systems.

    ERIC Educational Resources Information Center

    Chimi, Carl J.; Gordon, Gene M.

    This paper discusses a number of innovative techniques that were used to teach courses in Information Systems to undergraduate and graduate students. While none of these techniques is individually innovative, the combination of techniques provides a true "hands-on" environment for students; because of the way that the components of the…

  9. Integrated Information Systems. Course Six. Information Systems Curriculum.

    ERIC Educational Resources Information Center

    O'Neil, Sharon Lund; Everett, Donna R.

    This course is the sixth of seven in the Information Systems curriculum. The purpose of the course is to build on skills acquired in the earlier courses and to provide the student with skills that enable him/her to function as a resource person. Its focus is on concepts, applications, and skills as well as on equipment familiarity needed to…

  10. NICA project management information system

    NASA Astrophysics Data System (ADS)

    Bashashin, M. V.; Kekelidze, D. V.; Kostromin, S. A.; Korenkov, V. V.; Kuniaev, S. V.; Morozov, V. V.; Potrebenikov, Yu. K.; Trubnikov, G. V.; Philippov, A. V.

    2016-09-01

    The science projects growth, changing of the efficiency criteria during the project implementation require not only increasing of the management specialization level but also pose the problem of selecting the effective planning methods, monitoring of deadlines and interaction of participants involved in research projects. This paper is devoted to choosing the project management information system for the new heavy-ion collider NICA (Nuclotron based Ion Collider fAcility). We formulate the requirements for the project management information system with taking into account the specifics of the Joint Institute for Nuclear Research (JINR, Dubna, Russia) as an international intergovernmental research organization, which is developed on the basis of a flexible and effective information system for the NICA project management.

  11. BBIS: Beacon Bus Information System

    NASA Astrophysics Data System (ADS)

    Kasim, Shahreen; Hafit, Hanayanti; Pei Juin, Kong; Afizah Afif, Zehan; Hashim, Rathiah; Ruslai, Husni; Jahidin, Kamaruzzaman; Syafwan Arshad, Mohammad

    2016-11-01

    Lack of bus information for example bus timetable, status of the bus and messy advertisement on bulletin board at the bus stop will give negative impact to tourist. Therefore, a real-time update bus information bulletin board provides all information needed so that passengers can save their bus information searching time. Supported with Android or iOS, Beacon Bus Information System (BBIS) provides bus information between Batu Pahat and Kluang area. BBIS is a system that implements physical web technology and interaction on demand. It built on Backend-as-a-Service, a cloud solution and Firebase non relational database as data persistence backend and syncs between user client in the real-time. People walk through bus stop with smart device and do not require any application. Bluetooth Beacon is used to achieve smart device's best performance of data sharing. Intellij IDEA 15 is one of the tools that that used to develop the BBIS system. Multi-language included front end and backend supported Integration development environment (IDE) helped to speed up integration process.

  12. A Web Information Retrieval System

    NASA Astrophysics Data System (ADS)

    Kim, Tae-Hyun; Park, Dong-Chul; Huh, Woong; Kim, Hyen-Ug; Yoon, Chung-Hwa; Park, Chong-Dae; Woo, Dong-Min; Jeong, Taikyeong; Cho, Il-Hwan; Lee, Yunsik

    An approach for the retrieval of price information from internet sites is applied to real-world application problems in this paper. The Web Information Retrieval System (WIRS) utilizes Hidden Markov Model (HMM) for its powerful capability to process temporal information. HMM is an extremely flexible tool and has been successfully applied to a wide variety of stochastic modeling tasks. In order to compare the prices and features of products from various web sites, the WIRS extracts prices and descriptions of various products within web pages. The WIRS is evaluated with real-world problems and compared with a conventional method and the result is reported in this paper.

  13. Two Web-Based Laboratories of the FisL@bs Network: Hooke's and Snell's Laws

    ERIC Educational Resources Information Center

    de la Torre, L.; Sanchez, J.; Dormido, S.; Sanchez, J. P.; Yuste, M.; Carreras, C.

    2011-01-01

    FisL@bs is a network of remote and virtual laboratories for physics university education via the Internet that offers students the possibility of performing hands-on experiments in different fields of physics in two ways: simulation and real remote operation. This paper gives a detailed account of a novel way in physics in which distance learning…

  14. Two Web-Based Laboratories of the FisL@bs Network: Hooke's and Snell's Laws

    ERIC Educational Resources Information Center

    de la Torre, L.; Sanchez, J.; Dormido, S.; Sanchez, J. P.; Yuste, M.; Carreras, C.

    2011-01-01

    FisL@bs is a network of remote and virtual laboratories for physics university education via the Internet that offers students the possibility of performing hands-on experiments in different fields of physics in two ways: simulation and real remote operation. This paper gives a detailed account of a novel way in physics in which distance learning…

  15. Effects of Fis on Escherichia coli gene expression during different growth stages.

    PubMed

    Bradley, Meranda D; Beach, Michael B; de Koning, A P Jason; Pratt, Timothy S; Osuna, Robert

    2007-09-01

    Fis is a nucleoid-associated protein in Escherichia coli that is abundant during early exponential growth in rich medium but is in short supply during stationary phase. Its role as a transcriptional regulator has been demonstrated for an increasing number of genes. In order to gain insight into the global effects of Fis on E. coli gene expression during different stages of growth in rich medium, DNA microarray analyses were conducted in fis and wild-type strains during early, mid-, late-exponential and stationary growth phases. The results uncovered 231 significantly regulated genes that were distributed over 15 functional categories. Regulatory effects were observed at all growth stages examined. Coordinate upregulation was observed for a number of genes involved in translation, flagellar biosynthesis and motility, nutrient transport, carbon compound metabolism, and energy metabolism at different growth stages. Coordinate down-regulation was also observed for genes involved in stress response, amino acid and nucleotide biosynthesis, energy and intermediary metabolism, and nutrient transport. As cells transitioned from the early to the late-exponential growth phase, different functional categories of genes were regulated, and a gradual shift occurred towards mostly down-regulation. The results demonstrate that the growth phase-dependent Fis expression triggers coordinate regulation of 15 categories of functionally related genes during specific stages of growth of an E. coli culture.

  16. Early Childhood Educators and the FIS Grant Program: An Interview with Naomi Karp.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Elementary and Early Childhood Education, Champaign, IL.

    Naomi Karp is the Director of the National Institute on Early Childhood Development and Education (ECI) in the Office of Educational Research and Improvement (OERI) in the U.S. Department of Education. This interview concerns funding for early childhood education research through OERI's Field-Initiated Studies (FIS) Grant Program. Questions…

  17. Impact of fatigue in Parkinson's disease: the Fatigue Impact Scale for Daily Use (D-FIS).

    PubMed

    Martinez-Martin, Pablo; Catalan, Maria Jose; Benito-Leon, Julian; Moreno, Angel Ortega; Zamarbide, Ivana; Cubo, Esther; van Blercon, Nadeje; Arillo, Victor Campos; Pondal, Margarita; Linazasoro, Gurutz; Alonso, Fernando; Ruiz, Pedro García; Frades, Belen

    2006-05-01

    The Fatigue Impact Scale for Daily Use (D-FIS) was used in a cross-sectional study including 142 consecutive Parkinson's disease (PD) patients. Usual clinical measures for PD, the Montgomery-Asberg Depression Rating Scale and the Parkinson's Disease Questionnaire-8 items were applied. In addition to the D-FIS, patients with fatigue (67.6%, PWF) completed the Multidimensional Fatigue Inventory (MFI), a visual analogue scale for fatigue (VAS-F) and a Global Perception of Fatigue scale (GPF). Relevant psychometric D-FIS results were: floor effect = 4.2%; ceiling effect = 1.1%; skewness = 0.44; item homogeneity = 0.63; Cronbach's alpha = 0.93; item-total correlation = 0.68 (item 1)-0.82 (item 8); standard error of measurement = 2.15; convergent validity with other fatigue measures = 0.54 [GPF]-0.62 [VAS-F] (p<0.001). In a multiple linear regression model, fatigue, depression, and disability independently influenced HRQoL, as measured by the PDQ-8. Patients on amantadine had lower prevalence of fatigue. In PD, D-FIS is a consistent and valid measure for fatigue, a frequent symptom previously found to impair patients' HRQoL. Fatigue was also linked to depression and disability in this study.

  18. Processing information system for highly specialized information in corporate networks

    NASA Astrophysics Data System (ADS)

    Petrosyan, M. O.; Kovalev, I. V.; Zelenkov, P. V.; Brezitskaya, VV; Prohorovich, G. A.

    2016-11-01

    The new structure for formation system and management system for highly specialized information in corporate systems is offered. The main distinguishing feature of this structure is that it involves the processing of multilingual information in a single user request.

  19. Advanced Information Processing System (AIPS)

    NASA Technical Reports Server (NTRS)

    Pitts, Felix L.

    1993-01-01

    Advanced Information Processing System (AIPS) is a computer systems philosophy, a set of validated hardware building blocks, and a set of validated services as embodied in system software. The goal of AIPS is to provide the knowledgebase which will allow achievement of validated fault-tolerant distributed computer system architectures, suitable for a broad range of applications, having failure probability requirements of 10E-9 at 10 hours. A background and description is given followed by program accomplishments, the current focus, applications, technology transfer, FY92 accomplishments, and funding.

  20. Mass Storage Performance Information System

    NASA Technical Reports Server (NTRS)

    Scheuermann, Peter

    2000-01-01

    The purpose of this task is to develop a data warehouse to enable system administrators and their managers to gather information by querying the data logs of the MDSDS. Currently detailed logs capture the activity of the MDSDS internal to the different systems. The elements to be included in the data warehouse are requirements analysis, data cleansing, database design, database population, hardware/software acquisition, data transformation, query and report generation, and data mining.

  1. [Electronic poison information management system].

    PubMed

    Kabata, Piotr; Waldman, Wojciech; Kaletha, Krystian; Sein Anand, Jacek

    2013-01-01

    We describe deployment of electronic toxicological information database in poison control center of Pomeranian Center of Toxicology. System was based on Google Apps technology, by Google Inc., using electronic, web-based forms and data tables. During first 6 months from system deployment, we used it to archive 1471 poisoning cases, prepare monthly poisoning reports and facilitate statistical analysis of data. Electronic database usage made Poison Center work much easier.

  2. The ideal laboratory information system.

    PubMed

    Sepulveda, Jorge L; Young, Donald S

    2013-08-01

    Laboratory information systems (LIS) are critical components of the operation of clinical laboratories. However, the functionalities of LIS have lagged significantly behind the capacities of current hardware and software technologies, while the complexity of the information produced by clinical laboratories has been increasing over time and will soon undergo rapid expansion with the use of new, high-throughput and high-dimensionality laboratory tests. In the broadest sense, LIS are essential to manage the flow of information between health care providers, patients, and laboratories and should be designed to optimize not only laboratory operations but also personalized clinical care. To list suggestions for designing LIS with the goal of optimizing the operation of clinical laboratories while improving clinical care by intelligent management of laboratory information. Literature review, interviews with laboratory users, and personal experience and opinion. Laboratory information systems can improve laboratory operations and improve patient care. Specific suggestions for improving the function of LIS are listed under the following sections: (1) Information Security, (2) Test Ordering, (3) Specimen Collection, Accessioning, and Processing, (4) Analytic Phase, (5) Result Entry and Validation, (6) Result Reporting, (7) Notification Management, (8) Data Mining and Cross-sectional Reports, (9) Method Validation, (10) Quality Management, (11) Administrative and Financial Issues, and (12) Other Operational Issues.

  3. GEOGRAPHIC NAMES INFORMATION SYSTEM (GNIS) ...

    EPA Pesticide Factsheets

    The Geographic Names Information System (GNIS), developed by the U.S. Geological Survey in cooperation with the U.S. Board on Geographic Names (BGN), contains information about physical and cultural geographic features in the United States and associated areas, both current and historical, but not including roads and highways. The database also contains geographic names in Antarctica. The database holds the Federally recognized name of each feature and defines the location of the feature by state, county, USGS topographic map, and geographic coordinates. Other feature attributes include names or spellings other than the official name, feature designations, feature class, historical and descriptive information, and for some categories of features the geometric boundaries. The database assigns a unique feature identifier, a random number, that is a key for accessing, integrating, or reconciling GNIS data with other data sets. The GNIS is our Nation's official repository of domestic geographic feature names information.

  4. Policy Information System Computer Program.

    ERIC Educational Resources Information Center

    Hamlin, Roger E.; And Others

    The concepts and methodologies outlined in "A Policy Information System for Vocational Education" are presented in a simple computer format in this booklet. It also contains a sample output representing 5-year projections of various planning needs for vocational education. Computerized figures in the eight areas corresponding to those in the…

  5. Learning Information Systems: Theoretical Foundations.

    ERIC Educational Resources Information Center

    Paul, Terrance D.

    This paper uses the conceptual framework of cybernetics to understand why learning information systems such as the "Accelerated Reader" work so successfully, and to examine how this simple yet incisive concept can be used to accelerate learning at every level and in all disciplines. The first section, "Basic Concepts,"…

  6. Information Systems: Fact or Fiction.

    ERIC Educational Resources Information Center

    Bearley, William

    Rising costs of programming and program maintenance have caused discussion concerning the need for generalized information systems. These would provide data base functions plus complete report writing and file maintenance capabilities. All administrative applications, including online registration, student records, and financial applications are…

  7. Policy Information System Computer Program.

    ERIC Educational Resources Information Center

    Hamlin, Roger E.; And Others

    The concepts and methodologies outlined in "A Policy Information System for Vocational Education" are presented in a simple computer format in this booklet. It also contains a sample output representing 5-year projections of various planning needs for vocational education. Computerized figures in the eight areas corresponding to those in the…

  8. SRS Research Information System Thesaurus.

    ERIC Educational Resources Information Center

    Schultz, Claire K., Ed.

    For information storage and retrieval, a thesaurus is used during indexing and searching processes to translate from natural language into a more restricted retrieval system language. The purpose of this thesaurus is to control the language used to index and retrieve documents of interest to Social and Rehabilitation Service (SRS) and the…

  9. Information Systems: Fact or Fiction.

    ERIC Educational Resources Information Center

    Bearley, William

    Rising costs of programming and program maintenance have caused discussion concerning the need for generalized information systems. These would provide data base functions plus complete report writing and file maintenance capabilities. All administrative applications, including online registration, student records, and financial applications are…

  10. Information Systems, Security, and Privacy.

    ERIC Educational Resources Information Center

    Ware, Willis H.

    1984-01-01

    Computer security and computer privacy issues are discussed. Among the areas addressed are technical and human security threats, security and privacy issues for information in electronic mail systems, the need for a national commission to examine these issues, and security/privacy issues relevant to colleges and universities. (JN)

  11. Intensive Care Information System Impacts

    PubMed Central

    Ehteshami, Asghar; Sadoughi, Farahnaz; Ahmadi, Maryam; Kashefi, Parviz

    2013-01-01

    Introduction: Today, intensive care needs to be increased with a prospect of an aging population and socioeconomic factors influencing health intervention, but there are some problems in the intensive care environments, it is essential to resolve. The intensive Care information system has the potential to solve many of ICU problems. The objective of the review was to establish the impact of intensive care information systems on the practitioners practice, patient outcomes and ICU performance. Methods: Scientific databases and electronic journal citations was searched to identify articles that discussed the impacts of intensive care information system on the practices, patient outcomes and ICU performance. A total of 22 articles discussing ICIS outcomes was included in this study from 609 articles initially obtained from the searches. Results: Pooling data across studies, we found that the median impact of ICIS on information management was 48.7%. The median impact of ICIS on user’ outcomes was 36.4%, impact on saving tips by 24%, clinical decision support by a mean of 22.7%, clinical outcomes improved by a mean of 18.6%, and researches improved by 18%. Conclusion: The functionalities of ICIS are growing day by day and new functionalities are available with every major release. Better adoption of ICIS by the intensive care environments emphasizes the opportunity of better intensive care services through patient oriented intensive care clinical information systems. There is an immense need for developing guidelines for standardizing ICIS to to maximize the power of ICISs and to integrate with HISs. This will enable intensivists to use the systems in a more meaningful way for better patient care. This study provides a better understanding and greater insight into the effectiveness of ICIS in improving patient care and reducing health care expenses. PMID:24167389

  12. Centralized Storm Information System (CSIS)

    NASA Technical Reports Server (NTRS)

    Norton, C. C.

    1985-01-01

    A final progress report is presented on the Centralized Storm Information System (CSIS). The primary purpose of the CSIS is to demonstrate and evaluate real time interactive computerized data collection, interpretation and display techniques as applied to severe weather forecasting. CSIS objectives pertaining to improved severe storm forecasting and warning systems are outlined. The positive impact that CSIS has had on the National Severe Storms Forecast Center (NSSFC) is discussed. The benefits of interactive processing systems on the forecasting ability of the NSSFC are described.

  13. Marketing in Admissions: The Information System Approach.

    ERIC Educational Resources Information Center

    Wofford, O. Douglas; Timmerman, Ed

    1982-01-01

    A marketing information system approach for college admissions is outlined that includes objectives, information needs and sources, a data collection format, and information evaluation. Coordination with other institutional information systems is recommended. (MSE)

  14. PROMIS (Procurement Management Information System)

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The PROcurement Management Information System (PROMIS) provides both detailed and summary level information on all procurement actions performed within NASA's procurement offices at Marshall Space Flight Center (MSFC). It provides not only on-line access, but also schedules procurement actions, monitors their progress, and updates Forecast Award Dates. Except for a few computational routines coded in FORTRAN, the majority of the systems is coded in a high level language called NATURAL. A relational Data Base Management System called ADABAS is utilized. Certain fields, called descriptors, are set up on each file to allow the selection of records based on a specified value or range of values. The use of like descriptors on different files serves as the link between the falls, thus producing a relational data base. Twenty related files are currently being maintained on PROMIS.

  15. Respiratory care management information systems.

    PubMed

    Ford, Richard M

    2004-04-01

    Hospital-wide computerized information systems evolved from the need to capture patient information and perform billing and other financial functions. These systems, however, have fallen short of meeting the needs of respiratory care departments regarding work load assessment, productivity management, and the level of outcome reporting required to support programs such as patient-driven protocols. The respiratory care management information systems (RCMIS) of today offer many advantages over paper-based systems and hospital-wide computer systems. RCMIS are designed to facilitate functions specific to respiratory care, including assessing work demand, assigning and tracking resources, charting, billing, and reporting results. RCMIS incorporate mobile, point-of-care charting and are highly configurable to meet the specific needs of individual respiratory care departments. Important and substantial benefits can be realized with an RCMIS and mobile, wireless charting devices. The initial and ongoing costs of an RCMIS are justified by increased charge capture and reduced costs, by way of improved productivity and efficiency. It is not unusual to recover the total cost of an RCMIS within the first year of its operation. In addition, such systems can facilitate and monitor patient-care protocols and help to efficiently manage the vast amounts of information encountered during the practitioner's workday. Respiratory care departments that invest in RCMIS have an advantage in the provision of quality care and in reducing expenses. A centralized respiratory therapy department with an RCMIS is the most efficient and cost-effective way to monitor work demand and manage the hospital-wide allocation of respiratory care services.

  16. Fisher Information in Ecological Systems

    NASA Astrophysics Data System (ADS)

    Frieden, B. Roy; Gatenby, Robert A.

    Fisher information is being increasingly used as a tool of research into ecological systems. For example the information was shown in Chapter 7 to provide a useful diagnostic of the health of an ecology. In other applications to ecology, extreme physical information (EPI) has been used to derive the population-rate (or Lotka-Volterra) equations of ecological systems, both directly [1] and indirectly (Chapter 5) via the quantum Schrodinger wave equation (SWE). We next build on these results, to derive (i) an uncertainty principle (8.3) of biology, (ii) a simple decision rule (8.18) for predicting whether a given ecology is susceptible to a sudden drop in population (Section 8.1), (iii) the probability law (8.57) or (8.59) on the worldwide occurrence of the masses of living creatures from mice to elephants and beyond (Section 8.2), and (iv) the famous quarter-power laws for the attributes of biological and other systems. The latter approach uses EPI to derive the simultaneous quarter-power behavior of all attributes obeyed by the law, such as metabolism rate, brain size, grazing range, etc. (Section 8.3). This maximal breadth of scope is allowed by its basis in information, which of course applies to all types of quantitative data (Section 1.4.3, Chapter 1).

  17. Somerset County Flood Information System

    USGS Publications Warehouse

    Summer, William M.

    1998-01-01

    IntroductionThe timely warning of a flood is crucial to the protection of lives and property. One has only to recall the flood of August 2, 1973, in Somerset County, New Jersey, in which six lives were lost and major property damage occurred, to realize how unexpected and costly, especially in terms of human life, a flood can be. Accurate forecasts and warnings cannot be made, however, without detailed information about precipitation and streamflow in the drainage basin.Recognizing the need for detailed hydrologic information for Somerset County, the U.S. Geological Survey (USGS), in cooperation with Somerset County, installed the Somerset County Flood Information System (SCFIS) in 1990. The availability of data provided by this system will improve the flood forecasting ability of the National Weather Service (NWS), and has assisted Somerset County and municipal agencies in planning and execution of flood-preparation and emergency evacuation procedures in the county.This fact sheet describes the Somerset County Flood Information System and identifies its benefits.

  18. NEIS (NASA Environmental Information System)

    NASA Technical Reports Server (NTRS)

    Cook, Beth

    1995-01-01

    The NASA Environmental Information System (NEIS) is a tool to support the functions of the NASA Operational Environment Team (NOET). The NEIS is designed to provide a central environmental technology resource drawing on all NASA centers' capabilities, and to support program managers who must ultimately deliver hardware compliant with performance specifications and environmental requirements. The NEIS also tracks environmental regulations, usages of materials and processes, and new technology developments. It has proven to be a useful instrument for channeling information throughout the aerospace community, NASA, other federal agencies, educational institutions, and contractors. The associated paper will discuss the dynamic databases within the NEIS, and the usefulness it provides for environmental compliance efforts.

  19. Engineering Design Information System (EDIS)

    SciTech Connect

    Smith, P.S.; Short, R.D.; Schwarz, R.K.

    1990-11-01

    This manual is a guide to the use of the Engineering Design Information System (EDIS) Phase I. The system runs on the Martin Marietta Energy Systems, Inc., IBM 3081 unclassified computer. This is the first phase in the implementation of EDIS, which is an index, storage, and retrieval system for engineering documents produced at various plants and laboratories operated by Energy Systems for the Department of Energy. This manual presents on overview of EDIS, describing the system's purpose; the functions it performs; hardware, software, and security requirements; and help and error functions. This manual describes how to access EDIS and how to operate system functions using Database 2 (DB2), Time Sharing Option (TSO), Interactive System Productivity Facility (ISPF), and Soft Master viewing features employed by this system. Appendix A contains a description of the Soft Master viewing capabilities provided through the EDIS View function. Appendix B provides examples of the system error screens and help screens for valid codes used for screen entry. Appendix C contains a dictionary of data elements and descriptions.

  20. Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.

    PubMed

    Losón, Oliver C; Song, Zhiyin; Chen, Hsiuchen; Chan, David C

    2013-03-01

    Several mitochondrial outer membrane proteins-mitochondrial fission protein 1 (Fis1), mitochondrial fission factor (Mff), mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51, respectively)-have been proposed to promote mitochondrial fission by recruiting the GTPase dynamin-related protein 1 (Drp1), but fundamental issues remain concerning their function. A recent study supported such a role for Mff but not for Fis1. In addition, it is unclear whether MiD49 and MiD51 activate or inhibit fission, because their overexpression causes extensive mitochondrial elongation. It is also unknown whether these proteins can act in the absence of one another to mediate fission. Using Fis1-null, Mff-null, and Fis1/Mff-null cells, we show that both Fis1 and Mff have roles in mitochondrial fission. Moreover, immunofluorescence analysis of Drp1 suggests that Fis1 and Mff are important for the number and size of Drp1 puncta on mitochondria. Finally, we find that either MiD49 or MiD51 can mediate Drp1 recruitment and mitochondrial fission in the absence of Fis1 and Mff. These results demonstrate that multiple receptors can recruit Drp1 to mediate mitochondrial fission.

  1. Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

    PubMed Central

    Losón, Oliver C.; Song, Zhiyin; Chen, Hsiuchen; Chan, David C.

    2013-01-01

    Several mitochondrial outer membrane proteins—mitochondrial fission protein 1 (Fis1), mitochondrial fission factor (Mff), mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51, respectively)—have been proposed to promote mitochondrial fission by recruiting the GTPase dynamin-related protein 1 (Drp1), but fundamental issues remain concerning their function. A recent study supported such a role for Mff but not for Fis1. In addition, it is unclear whether MiD49 and MiD51 activate or inhibit fission, because their overexpression causes extensive mitochondrial elongation. It is also unknown whether these proteins can act in the absence of one another to mediate fission. Using Fis1-null, Mff-null, and Fis1/Mff-null cells, we show that both Fis1 and Mff have roles in mitochondrial fission. Moreover, immunofluorescence analysis of Drp1 suggests that Fis1 and Mff are important for the number and size of Drp1 puncta on mitochondria. Finally, we find that either MiD49 or MiD51 can mediate Drp1 recruitment and mitochondrial fission in the absence of Fis1 and Mff. These results demonstrate that multiple receptors can recruit Drp1 to mediate mitochondrial fission. PMID:23283981

  2. The risk assessment information system

    SciTech Connect

    Kerr, S.B.; Bonczek, R.R.; McGinn, C.W.; Land, M.L.; Bloom, L.D.; Sample, B.E.; Dolislager, F.G.

    1998-06-01

    In an effort to provide service-oriented environmental risk assessment expertise, the Department of Energy (DOE) Center for Risk Excellence (CRE) and DOE Oak Ridge Operations Office (ORO) are sponsoring Oak Ridge National Laboratory (ORNL) to develop a web-based system for disseminating risk tools and information to its users. This system, the Risk Assessment Information System (RAIS), was initially developed to support the site-specific needs of the DOE-ORO Environmental Restoration Risk Assessment Program. With support from the CRE, the system is currently being expanded to benefit all DOE risk information users and can be tailored to meet site-specific needs. Taking advantage of searchable and executable databases, menu-driven queries, and data downloads, using the latest World Wide Web technologies, the RAIS offers essential tools that are used in the risk assessment process or anywhere from project scoping to implementation. The RAIS tools can be located directly at http://risk.lsd.ornl.gov/homepage/rap{_}tool.htm or through the CRE`s homepage at http://www.doe.gov/riskcenter/home.html.

  3. Database Systems. Course Three. Information Systems Curriculum.

    ERIC Educational Resources Information Center

    O'Neil, Sharon Lund; Everett, Donna R.

    This course is the third of seven in the Information Systems curriculum. The purpose of the course is to familiarize students with database management concepts and standard database management software. Databases and their roles, advantages, and limitations are explained. An overview of the course sets forth the condition and performance standard…

  4. Joint Operational Medicine Information Systems (JOMIS)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Joint Operational Medicine Information Systems (JOMIS) Defense Acquisition Management ...Automated Information System MAIS OE - MAIS Original Estimate MAR – MAIS Annual Report MDA - Milestone Decision Authority MDD - Materiel Development...August 24, 2015 Program Information Program Name Joint Operational Medicine Information Systems (JOMIS) DoD Component DoD The acquiring DoD

  5. Information systems vulnerability: A systems analysis perspective

    SciTech Connect

    Wyss, G.D.; Daniel, S.L.; Schriner, H.K.; Gaylor, T.R.

    1996-07-01

    Vulnerability analyses for information systems are complicated because the systems are often geographically distributed. Sandia National Laboratories has assembled an interdisciplinary team to explore the applicability of probabilistic logic modeling (PLM) techniques (including vulnerability and vital area analysis) to examine the risks associated with networked information systems. The authors have found that the reliability and failure modes of many network technologies can be effectively assessed using fault trees and other PLM methods. The results of these models are compatible with an expanded set of vital area analysis techniques that can model both physical locations and virtual (logical) locations to identify both categories of vital areas simultaneously. These results can also be used with optimization techniques to direct the analyst toward the most cost-effective security solution.

  6. Automated Information System (AIS) Alarm System

    SciTech Connect

    Hunteman, W.

    1997-05-01

    The Automated Information Alarm System is a joint effort between Los Alamos National Laboratory, Lawrence Livermore National Laboratory, and Sandia National Laboratory to demonstrate and implement, on a small-to-medium sized local area network, an automated system that detects and automatically responds to attacks that use readily available tools and methodologies. The Alarm System will sense or detect, assess, and respond to suspicious activities that may be detrimental to information on the network or to continued operation of the network. The responses will allow stopping, isolating, or ejecting the suspicious activities. The number of sensors, the sensitivity of the sensors, the assessment criteria, and the desired responses may be set by the using organization to meet their local security policies.

  7. Multifunctional Information Distribution System (MIDS)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-554 Multifunctional Information Distribution System (MIDS) As of FY 2017 President’s Budget...Program Office Estimate RDT&E - Research, Development, Test, and Evaluation SAR - Selected Acquisition Report SCP - Service Cost Position TBD - To Be... selectable levels Multiple selectable levels >=200 with IF for 1000 200 with IF Multiple selectable levels LVT(2) Multiple selectable levels Multiple

  8. Image and information management system

    NASA Technical Reports Server (NTRS)

    Robertson, Tina L. (Inventor); Raney, Michael C. (Inventor); Dougherty, Dennis M. (Inventor); Kent, Peter C. (Inventor); Brucker, Russell X. (Inventor); Lampert, Daryl A. (Inventor)

    2009-01-01

    A system and methods through which pictorial views of an object's configuration, arranged in a hierarchical fashion, are navigated by a person to establish a visual context within the configuration. The visual context is automatically translated by the system into a set of search parameters driving retrieval of structured data and content (images, documents, multimedia, etc.) associated with the specific context. The system places ''hot spots'', or actionable regions, on various portions of the pictorials representing the object. When a user interacts with an actionable region, a more detailed pictorial from the hierarchy is presented representing that portion of the object, along with real-time feedback in the form of a popup pane containing information about that region, and counts-by-type reflecting the number of items that are available within the system associated with the specific context and search filters established at that point in time.

  9. Image and information management system

    NASA Technical Reports Server (NTRS)

    Robertson, Tina L. (Inventor); Raney, Michael C. (Inventor); Dougherty, Dennis M. (Inventor); Kent, Peter C. (Inventor); Brucker, Russell X. (Inventor); Lampert, Daryl A. (Inventor)

    2007-01-01

    A system and methods through which pictorial views of an object's configuration, arranged in a hierarchical fashion, are navigated by a person to establish a visual context within the configuration. The visual context is automatically translated by the system into a set of search parameters driving retrieval of structured data and content (images, documents, multimedia, etc.) associated with the specific context. The system places hot spots, or actionable regions, on various portions of the pictorials representing the object. When a user interacts with an actionable region, a more detailed pictorial from the hierarchy is presented representing that portion of the object, along with real-time feedback in the form of a popup pane containing information about that region, and counts-by-type reflecting the number of items that are available within the system associated with the specific context and search filters established at that point in time.

  10. Large-Scale Information Systems

    SciTech Connect

    D. M. Nicol; H. R. Ammerlahn; M. E. Goldsby; M. M. Johnson; D. E. Rhodes; A. S. Yoshimura

    2000-12-01

    Large enterprises are ever more dependent on their Large-Scale Information Systems (LSLS), computer systems that are distinguished architecturally by distributed components--data sources, networks, computing engines, simulations, human-in-the-loop control and remote access stations. These systems provide such capabilities as workflow, data fusion and distributed database access. The Nuclear Weapons Complex (NWC) contains many examples of LSIS components, a fact that motivates this research. However, most LSIS in use grew up from collections of separate subsystems that were not designed to be components of an integrated system. For this reason, they are often difficult to analyze and control. The problem is made more difficult by the size of a typical system, its diversity of information sources, and the institutional complexities associated with its geographic distribution across the enterprise. Moreover, there is no integrated approach for analyzing or managing such systems. Indeed, integrated development of LSIS is an active area of academic research. This work developed such an approach by simulating the various components of the LSIS and allowing the simulated components to interact with real LSIS subsystems. This research demonstrated two benefits. First, applying it to a particular LSIS provided a thorough understanding of the interfaces between the system's components. Second, it demonstrated how more rapid and detailed answers could be obtained to questions significant to the enterprise by interacting with the relevant LSIS subsystems through simulated components designed with those questions in mind. In a final, added phase of the project, investigations were made on extending this research to wireless communication networks in support of telemetry applications.

  11. Information Security and Integrity Systems

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Viewgraphs from the Information Security and Integrity Systems seminar held at the University of Houston-Clear Lake on May 15-16, 1990 are presented. A tutorial on computer security is presented. The goals of this tutorial are the following: to review security requirements imposed by government and by common sense; to examine risk analysis methods to help keep sight of forest while in trees; to discuss the current hot topic of viruses (which will stay hot); to examine network security, now and in the next year to 30 years; to give a brief overview of encryption; to review protection methods in operating systems; to review database security problems; to review the Trusted Computer System Evaluation Criteria (Orange Book); to comment on formal verification methods; to consider new approaches (like intrusion detection and biometrics); to review the old, low tech, and still good solutions; and to give pointers to the literature and to where to get help. Other topics covered include security in software applications and development; risk management; trust: formal methods and associated techniques; secure distributed operating system and verification; trusted Ada; a conceptual model for supporting a B3+ dynamic multilevel security and integrity in the Ada runtime environment; and information intelligence sciences.

  12. Information Security and Integrity Systems

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Viewgraphs from the Information Security and Integrity Systems seminar held at the University of Houston-Clear Lake on May 15-16, 1990 are presented. A tutorial on computer security is presented. The goals of this tutorial are the following: to review security requirements imposed by government and by common sense; to examine risk analysis methods to help keep sight of forest while in trees; to discuss the current hot topic of viruses (which will stay hot); to examine network security, now and in the next year to 30 years; to give a brief overview of encryption; to review protection methods in operating systems; to review database security problems; to review the Trusted Computer System Evaluation Criteria (Orange Book); to comment on formal verification methods; to consider new approaches (like intrusion detection and biometrics); to review the old, low tech, and still good solutions; and to give pointers to the literature and to where to get help. Other topics covered include security in software applications and development; risk management; trust: formal methods and associated techniques; secure distributed operating system and verification; trusted Ada; a conceptual model for supporting a B3+ dynamic multilevel security and integrity in the Ada runtime environment; and information intelligence sciences.

  13. The Global Land Information System

    NASA Astrophysics Data System (ADS)

    Oleson, Lyndon R.

    1993-08-01

    The Global Land Information System (GLIS) is an interactive computer system being developed by the U.S. Geological Survey for scientists seeking data pertaining to the Earth's land surface that can be used in global change studies. GLIS contains descriptive information on a variety of regional, continental, and global land data sets. The interactive query services of GLIS allow scientists to assess the potential utility of data sets, determine their availability, and place online requests for data products. In addition to the text-based query services, GLIS offers a number of graphical aids to users accessing the system through one of the supported graphical user interfaces, such as the PG-GLIS package developed for IBM-compatible personal computers. These services include interative specification of geographic search areas, geographic coverage plots, and online digital image browse capabilities. Access to GLIS is provided through either wide-area network or dial-up interfaces. A prototype of the system became operational in June 1991, and full operational status is expected by September 1992. In addition to continued data set expansion, 1992 development plans include the enhancement of data query and visualization services and the addition of a graphical user interface for UNIX workstations.

  14. Buying a healthcare information system.

    PubMed

    Clegg, T A

    1998-01-01

    Replacing an antiquated computer system with state of the art equipment and software is a lengthy, at times frustrating, and never an easy decision. At Wesley Woods Center on Aging, Atlanta, an integrated provider of healthcare for the elderly affiliated with Emory University, the process consumed more than two and a half years. This article takes the reader through the entire process, from the initial decision to replace an existing system, through the final purchase and installation. It looks candidly at the problems that were encountered, including turnover among key personnel, difficulties with involving all of the user groups, changes in the technology and coordination with the University. The lessons Wesley Woods learned in its experience can be of benefit to any healthcare facility contemplating an information system change.

  15. Effects of N-terminal deletions of the Escherichia coli protein Fis on growth rate, tRNA(2Ser) expression and cell morphology.

    PubMed

    Spaeny-Dekking, L; Nilsson, L; von Euler, A; van de Putte, P; Goosen, N

    1995-01-20

    The Escherichia coli Fis protein is known to be involved in a variety of processes, including the activation of stable RNA operons. In this paper we study the ability of a set of N-terminal Fis deletion mutants to stimulate transcription of the tRNA(2Ser) gene. The results indicate that the domain of the Fis protein containing residues 1-26 is not required for transcription activation. The Fis mutants that are still active in transcription stimulation can also complement the reduced growth rates of Fis- cells, suggesting that the same activating domain is involved in this phenomenon. In addition, we show that in fast growing cultures in the absence of an active Fis protein, minicells are formed. These minicells seem to arise from septum formation near the cell poles. Suppression of minicell formation by Fis also does not require the presence of the N-terminal domain of the protein.

  16. BIRS - Bioterrorism Information Retrieval System.

    PubMed

    Tewari, Ashish Kumar; Rashi; Wadhwa, Gulshan; Sharma, Sanjeev Kumar; Jain, Chakresh Kumar

    2013-01-01

    Bioterrorism is the intended use of pathogenic strains of microbes to widen terror in a population. There is a definite need to promote research for development of vaccines, therapeutics and diagnostic methods as a part of preparedness to any bioterror attack in the future. BIRS is an open-access database of collective information on the organisms related to bioterrorism. The architecture of database utilizes the current open-source technology viz PHP ver 5.3.19, MySQL and IIS server under windows platform for database designing. Database stores information on literature, generic- information and unique pathways of about 10 microorganisms involved in bioterrorism. This may serve as a collective repository to accelerate the drug discovery and vaccines designing process against such bioterrorist agents (microbes). The available data has been validated from various online resources and literature mining in order to provide the user with a comprehensive information system. The database is freely available at http://www.bioterrorism.biowaves.org.

  17. The Femininity Ideology Scale (FIS): dimensions and its relationship to anxiety and feminine gender role stress.

    PubMed

    Richmond, Katherine; Levant, Ronald; Smalley, Bryant; Cook, Stephen

    2015-01-01

    The purpose of this study was to conduct a confirmatory factor analytic investigation of the Femininity Ideology Scale (FIS) and to assess whether feminine gender role stress mediated the relationship between femininity ideology and anxiety. During the 2010-2011 academic year, a convenience sample of 606 college women were recruited from three universities and one college. Confirmatory factor analysis supported a four- versus the hypothesized five-factor model, resulting in the elimination of the Dependency/Deference factor. Mediation analysis using structural equation modeling indicated no direct relationship between Femininity Ideology and Anxiety, although an indirect one was observed, mediated through Feminine Gender Role Stress. The results are discussed in terms of possible changes in contemporary notions of femininity, and the utility of using the FIS in applied therapeutic settings.

  18. Advanced information processing system: Local system services

    NASA Technical Reports Server (NTRS)

    Burkhardt, Laura; Alger, Linda; Whittredge, Roy; Stasiowski, Peter

    1989-01-01

    The Advanced Information Processing System (AIPS) is a multi-computer architecture composed of hardware and software building blocks that can be configured to meet a broad range of application requirements. The hardware building blocks are fault-tolerant, general-purpose computers, fault-and damage-tolerant networks (both computer and input/output), and interfaces between the networks and the computers. The software building blocks are the major software functions: local system services, input/output, system services, inter-computer system services, and the system manager. The foundation of the local system services is an operating system with the functions required for a traditional real-time multi-tasking computer, such as task scheduling, inter-task communication, memory management, interrupt handling, and time maintenance. Resting on this foundation are the redundancy management functions necessary in a redundant computer and the status reporting functions required for an operator interface. The functional requirements, functional design and detailed specifications for all the local system services are documented.

  19. Applied Information Systems Research Program Workshop

    NASA Technical Reports Server (NTRS)

    Bredekamp, Joe

    1991-01-01

    Viewgraphs on Applied Information Systems Research Program Workshop are presented. Topics covered include: the Earth Observing System Data and Information System; the planetary data system; Astrophysics Data System project review; OAET Computer Science and Data Systems Programs; the Center of Excellence in Space Data and Information Sciences; and CASIS background.

  20. Telematics and satellites. Part 1: Information systems

    NASA Astrophysics Data System (ADS)

    Burke, W. R.

    1980-06-01

    Telematic systems are identified and described. The applications are examined emphasizing the role played by satellite links. The discussion includes file transfer, examples of distributed processor systems, terminal communication, information retrieval systems, office information systems, electronic preparation and publishing of information, electronic systems for transfer of funds, electronic mail systems, record file transfer characteristics, intra-enterprise networks, and inter-enterprise networks.

  1. Centralized versus Decentralized Information Systems

    NASA Astrophysics Data System (ADS)

    Hugoson, Mats-Åke

    This paper brings into question whether information systems should be centralized or decentralized in order to provide greater support for different business processes. During the last century companies and organizations have used different approaches for centralization and decentralization; a simple answer to the question does not exist. This paper provides a survey of the evolution of centralized and decentralized approaches, mainly in a Nordic perspective. Based on critical reflections on the situation in the end of the century we can discuss what we can learn from history to achieve alignment between centralized and decentralized systems and the business structure. The conclusion is that theories, management and practice for decisions on centralization or decentralization of information systems must be improved. A conscious management and control of centralization /decentralization of IT support is a vital question in the company or the organization, and this is not a task that can be handled only by IT-specialists. There is a need for business oriented IT management of centralization/decentralization.

  2. 75 FR 23834 - Occupational Information System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... ADMINISTRATION Occupational Information System AGENCY: Social Security Administration (SSA). ACTION: Request for... Recommendations for the Social Security Administration Occupational Information System, September 2009.'' The... to provide independent advice and recommendations on creating an occupational information...

  3. The Co-Creation of Information Systems

    ERIC Educational Resources Information Center

    Gomillion, David

    2013-01-01

    In information systems development, end-users have shifted in their role: from consumers of information to informants for requirements to developers of systems. This shift in the role of users has also changed how information systems are developed. Instead of systems developers creating specifications for software or end-users creating small…

  4. Status of Statewide Career Information Delivery Systems.

    ERIC Educational Resources Information Center

    Dunn, Wynonia L.

    Intended as a resource document as well as a status report on all the statewide career information delivery systems (CIDS) in operation, this report examines the status of 39 statewide information systems. (Career information delivery systems are computer-based systems that provide national, state, and local information to individuals who are in…

  5. The Co-Creation of Information Systems

    ERIC Educational Resources Information Center

    Gomillion, David

    2013-01-01

    In information systems development, end-users have shifted in their role: from consumers of information to informants for requirements to developers of systems. This shift in the role of users has also changed how information systems are developed. Instead of systems developers creating specifications for software or end-users creating small…

  6. Evaluating geographic information systems technology

    USGS Publications Warehouse

    Guptill, Stephen C.

    1989-01-01

    Computerized geographic information systems (GISs) are emerging as the spatial data handling tools of choice for solving complex geographical problems. However, few guidelines exist for assisting potential users in identifying suitable hardware and software. A process to be followed in evaluating the merits of GIS technology is presented. Related standards and guidelines, software functions, hardware components, and benchmarking are discussed. By making users aware of all aspects of adopting GIS technology, they can decide if GIS is an appropriate tool for their application and, if so, which GIS should be used.

  7. A dedicated translation factor controls the synthesis of the global regulator Fis

    PubMed Central

    Owens, Róisín M; Pritchard, Gareth; Skipp, Paul; Hodey, Michelle; Connell, Sean R; Nierhaus, Knud H; O'Connor, C David

    2004-01-01

    BipA is a highly conserved protein with global regulatory properties in Escherichia coli. We show here that it functions as a translation factor that is required specifically for the expression of the transcriptional modulator Fis. BipA binds to ribosomes at a site that coincides with that of elongation factor G and has a GTPase activity that is sensitive to high GDP:GTP ratios and stimulated by 70S ribosomes programmed with mRNA and aminoacylated tRNAs. The growth rate-dependent induction of BipA allows the efficient expression of Fis, thereby modulating a range of downstream processes, including DNA metabolism and type III secretion. We propose a model in which BipA destabilizes unusually strong interactions between the 5′ untranslated region of fis mRNA and the ribosome. Since BipA spans phylogenetic domains, transcript-selective translational control for the ‘fast-track' expression of specific mRNAs may have wider significance. PMID:15297874

  8. Identification of susceptibility loci for scoliosis in FIS families with triple curves.

    PubMed

    Marosy, Beth; Justice, Cristina M; Vu, Cuong; Zorn, Andrew; Nzegwu, Nneka; Wilson, Alexander F; Miller, Nancy H

    2010-04-01

    The triple curve pattern (three lateral curvatures of equal severity) has been recognized as a distinct and unique clinical subtype of scoliosis. As part of a large study of familial idiopathic scoliosis (FIS), a subset of five families with a triple curve pattern (at least one member of each family having a triple curve) was evaluated to determine if this curve pattern was linked to any of the markers previously genotyped as part of the STRP-based previous linkage screen. Model independent linkage analysis (SIBPAL, v4.5) of the initial genomic screen identified candidate regions on chromosomes 6 and 10 when FIS was analyzed both as qualitative and quantitative traits in single- and multipoint linkage analyses. Additional fine mapping analyses of this subgroup with SNPs corroborated the findings in these regions (P < 0.001). These regions have been previously linked to FIS, however, this is the first time these regions have been implicated in a clinically well-defined subgroup and may suggest a unique genetic etiology for the formation of a triple curve.

  9. CAIS. Condition Assessment Information System

    SciTech Connect

    Oak, J.C.

    1996-09-30

    CAIS is used by Architects and Engineers to gather facility condition assessment data. This data consist of architectural, civil, structural, electrical, and mechanical systems and components that are a part of the inspected facility. Data is collected using a hand-held, pen-based computer system which is preprogrammed for detailed inventories of individual components. The program is deficiency based for collecting data for repair and replacement observations. Observations are recorded on checklists preformatted to individual site needs, allowing for comments on unusual conditions to be documented on site. Data is transferred to a central database, where it can be reviewed, costed, and reported on using different scenarios. Information can be transferred to the DOE operations offices as well as to the DOE FIMS database for each site.

  10. Dynamic information theory and information description of dynamic systems

    NASA Astrophysics Data System (ADS)

    Xing, Xiusan

    2010-04-01

    In this paper, we develop dynamic statistical information theory established by the author. Starting from the ideas that the state variable evolution equations of stochastic dynamic systems, classical and quantum nonequilibrium statistical physical systems and special electromagnetic field systems can be regarded as their information symbol evolution equations and the definitions of dynamic information and dynamic entropy, we derive the evolution equations of dynamic information and dynamic entropy that describe the evolution laws of dynamic information. These four kinds of evolution equations are of the same mathematical type. They show in unison when information transmits in coordinate space outside the systems that the time rate of change of dynamic information densities originates from their drift, diffusion and dissipation in state variable space inside the systems and coordinate space in the transmission processes, and that the time rate of change of dynamic entropy densities is caused by their drift, diffusion and production in state variable space inside the systems and coordinate space in the transmission processes. When space noise can be neglected, an information wave will appear. If we only consider the information change inside the systems, dynamic information evolution equations reduce to information equations corresponding to the dynamic equations which describe evolution laws of the above dynamic systems. This reveals that the evolution laws of respective dynamic systems can be described by information equations in a unified fashion. Hence, the evolution processes of these dynamic systems can be abstracted as the evolution processes of information. Furthermore, we present the formulas for information flow, information dissipation rate, and entropy production rate. We prove that the information production probably emerges in a dynamic system with internal attractive interaction between the elements, and derive a formula for this information

  11. Activation of transcription initiation from a stable RNA promoter by a Fis protein-mediated DNA structural transmission mechanism.

    PubMed

    Opel, Michael L; Aeling, Kimberly A; Holmes, Walter M; Johnson, Reid C; Benham, Craig J; Hatfield, G Wesley

    2004-07-01

    The leuV operon of Escherichia coli encodes three of the four genes for the tRNA1Leu isoacceptors. Transcription from this and other stable RNA promoters is known to be affected by a cis-acting UP element and by Fis protein interactions with the carboxyl-terminal domain of the alpha-subunits of RNA polymerase. In this report, we suggest that transcription from the leuV promoter also is activated by a Fis-mediated, DNA supercoiling-dependent mechanism similar to the IHF-mediated mechanism described previously for the ilvP(G) promoter (S. D. Sheridan et al., 1998, J Biol Chem 273: 21298-21308). We present evidence that Fis binding results in the translocation of superhelical energy from the promoter-distal portion of a supercoiling-induced DNA duplex destabilized (SIDD) region to the promoter-proximal portion of the leuV promoter that is unwound within the open complex. A mutant Fis protein, which is defective in contacting the carboxyl-terminal domain of the alpha-subunits of RNA polymerase, remains competent for stimulating open complex formation, suggesting that this DNA supercoiling-dependent component of Fis-mediated activation occurs in the absence of specific protein interactions between Fis and RNA polymerase. Fis-mediated translocation of superhelical energy from upstream binding sites to the promoter region may be a general feature of Fis-mediated activation of transcription at stable RNA promoters, which often contain A+T-rich upstream sequences.

  12. RBIS - An Environmental Information System

    NASA Astrophysics Data System (ADS)

    Zander, F.; Kralisch, S.

    2012-04-01

    The River Basin Information System (RBIS) developed at the Department of Geoinformatics at the Friedrich Schiller University of Jena provides a modular structured and web-based platform for environmental data management and data sharing (http://www.rbis.uni-jena.de). The system is used in several multidisciplinary research projects and provides user-friendly functions for the management, analysis, visualization and presentation of different types of data. These types of data include time series data (e.g. hydrological, climatologically …), geodata, documents and more domain specific modules for example related to soil, vegetation, scenarios, simulation models or indicators. One main focus lies on the maintenance on meta-data to make sure information about data provenance and responsible parties are preserved. Furthermore the fine grained user and permission management of RBIS take care about the access and manipulation rights of all stored data. For an easy data exchange of time series data and other data types RBIS provides several interfaces. One example is a prototypical implementation using OGC standards (Sensor Observation Service (SOS) and WaterML2.0). Since RBIS is used for data in research regions located in different countries (e.g. Brazil, Vietnam, Angola, Chile, Germany) a Multilanguage support was added to address not only research project partners but also local stakeholder and public. We will present the structure, modules, main functions, permission management and interfaces for data exchange of RBIS together with selected examples of RBIS instances.

  13. Somerset County Flood Information System

    USGS Publications Warehouse

    Hoppe, Heidi L.

    2007-01-01

    The timely warning of a flood is crucial to the protection of lives and property. One has only to recall the floods of August 2, 1973, September 16 and 17, 1999, and April 16, 2007, in Somerset County, New Jersey, in which lives were lost and major property damage occurred, to realize how costly, especially in terms of human life, an unexpected flood can be. Accurate forecasts and warnings cannot be made, however, without detailed information about precipitation and streamflow in the drainage basin. Since the mid 1960's, the National Weather Service (NWS) has been able to forecast flooding on larger streams in Somerset County, such as the Raritan and Millstone Rivers. Flooding on smaller streams in urban areas was more difficult to predict. In response to this problem the NWS, in cooperation with the Green Brook Flood Control Commission, installed a precipitation gage in North Plainfield, and two flash-flood alarms, one on Green Brook at Seeley Mills and one on Stony Brook at Watchung, in the early 1970's. In 1978, New Jersey's first countywide flood-warning system was installed by the U.S. Geological Survey (USGS) in Somerset County. This system consisted of a network of eight stage and discharge gages equipped with precipitation gages linked by telephone telemetry and eight auxiliary precipitation gages. The gages were installed throughout the county to collect precipitation and runoff data that could be used to improve flood-monitoring capabilities and flood-frequency estimates. Recognizing the need for more detailed hydrologic information for Somerset County, the USGS, in cooperation with Somerset County, designed and installed the Somerset County Flood Information System (SCFIS) in 1990. This system is part of a statewide network of stream gages, precipitation gages, weather stations, and tide gages that collect data in real time. The data provided by the SCFIS improve the flood forecasting ability of the NWS and aid Somerset County and municipal agencies in

  14. An Intelligent Pictorial Information System

    NASA Astrophysics Data System (ADS)

    Lee, Edward T.; Chang, B.

    1987-05-01

    In examining the history of computer application, we discover that early computer systems were developed primarily for applications related to scientific computation, as in weather prediction, aerospace applications, and nuclear physics applications. At this stage, the computer system served as a big calculator to perform, in the main, manipulation of numbers. Then it was found that computer systems could also be used for business applications, information storage and retrieval, word processing, and report generation. The history of computer application is summarized in Table I. The complexity of pictures makes picture processing much more difficult than number and alphanumerical processing. Therefore, new techniques, new algorithms, and above all, new pictorial knowledge, [1] are needed to overcome the limitatins of existing computer systems. New frontiers in designing computer systems are the ways to handle the representation,[2,3] classification, manipulation, processing, storage, and retrieval of pictures. Especially, the ways to deal with similarity measures and the meaning of the word "approximate" and the phrase "approximate reasoning" are an important and an indispensable part of an intelligent pictorial information system. [4,5] The main objective of this paper is to investigate the mathematical foundation for the effective organization and efficient retrieval of pictures in similarity-directed pictorial databases, [6] based on similarity retrieval techniques [7] and fuzzy languages [8]. The main advantage of this approach is that similar pictures are stored logically close to each other by using quantitative similarity measures. Thus, for answering queries, the amount of picture data needed to be searched can be reduced and the retrieval time can be improved. In addition, in a pictorial database, very often it is desired to find pictures (or feature vectors, histograms, etc.) that are most similar to or most dissimilar [9] to a test picture (or feature

  15. FisR activates σ(54) -dependent transcription of sulfide-oxidizing genes in Cupriavidus pinatubonensis JMP134.

    PubMed

    Li, Huanjie; Li, Juan; Lü, Chuanjuan; Xia, Yongzhen; Xin, Yufeng; Liu, Honglei; Xun, Luying; Liu, Huaiwei

    2017-08-01

    Some heterotrophic bacteria are able to oxidize sulfide (H2 S, HS(-) and S(2-) ) to sulfite and thiosulfate via polysulfide. The genes coding for the oxidation enzymes in Cupriavidus pinatubonensis JMP134 have recently been identified; however, their regulation is unknown. A regulator gene is adjacent to the operon of the sulfide-oxidizing genes, encoding a σ(54) -dependent transcription factor (FisR) with three domains: an R domain, an AAA+ domain and a DNA-binding domain. Here it is reported that the regulator responds to the presence of sulfide and activates the sulfide-oxidizing genes. FisR binds to its cognate operator at -114 to -135 bp of the transcription start of the operon. When polysulfide reacts with the R domain of FisR through the three conserved cysteine residues (C53, C64 and C71), FisR activates the expression of the operon. FisR is highly sensitive to polysulfide, activating σ(54) -dependent transcription of sulfide-oxidizing genes for sulfide removal. Further, sequence analysis indicates that FisR-type regulators are relatively common for controlling sulfide-oxidizing genes under sulfide stress in the Proteobacteria. © 2017 John Wiley & Sons Ltd.

  16. CIMS: The Cartographic Information Management System,

    DTIC Science & Technology

    1981-01-01

    evmee side if neceaety mid identity by block number) Information Management Microcomputer Tii-eractive Cartography ’I A STACT (Cubs me mverse eggs...use. Large-scale information systems may cover large amounts of information such as the Land Identification and Information Management System (LIMS...small computer in managing the information holdings of a mapping institute. The result is the Cartographic Information Management System (CIMS), a

  17. The Intelligent Technologies of Electronic Information System

    NASA Astrophysics Data System (ADS)

    Li, Xianyu

    2017-08-01

    Based upon the synopsis of system intelligence and information services, this paper puts forward the attributes and the logic structure of information service, sets forth intelligent technology framework of electronic information system, and presents a series of measures, such as optimizing business information flow, advancing data decision capability, improving information fusion precision, strengthening deep learning application and enhancing prognostic and health management, and demonstrates system operation effectiveness. This will benefit the enhancement of system intelligence.

  18. A Commentary on the Biomedical Information System

    ERIC Educational Resources Information Center

    Stokes, Joseph, III; Hayes, Robert M.

    1970-01-01

    The Biomedical Information System is described as one which includes closed intermediate and open data, mobilizing all biomedical information for physicians, teachers, students and administrators. (Editor/IE)

  19. Expression of the Fis protein is sustained in late-exponential- and stationary-phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration.

    PubMed

    O Cróinín, Tadhg; Dorman, Charles J

    2007-10-01

    The classic expression pattern of the Fis global regulatory protein during batch culture consists of a high peak in the early logarithmic phase of growth, followed by a sharp decrease through mid-exponential growth phase until Fis is almost undetectable at the end of the exponential phase. We discovered that this pattern is contingent on the growth regime. In Salmonella enterica serovar Typhimurium cultures grown in non-aerated SPI1-inducing conditions, Fis can be detected readily in stationary phase. On the other hand, cultures grown with standard aeration showed the classic Fis expression pattern. Sustained Fis expression in non-aerated cultures was also detected in some Escherichia coli strains, but not in others. This novel pattern of Fis expression was independent of sequence differences in the fis promoter regions of Salmonella and E. coli. Instead, a clear negative correlation between the expression of the Fis protein and of the stress-and-stationary-phase sigma factor RpoS was observed in a variety of strains. An rpoS mutant displayed elevated levels of Fis and had a higher frequency of epithelial cell invasion under these growth conditions. We discuss a model whereby Fis and RpoS levels vary in response to environmental signals allowing the expression and repression of SPI1 invasion genes.

  20. Information Systems Coordinate Emergency Management

    NASA Technical Reports Server (NTRS)

    2012-01-01

    -changing planet. This information can be captured, analyzed, and visualized by geographic information systems (GIS) to produce maps, charts, and other tools that can reveal information essential to a wide variety of applications including emergency management. Knowing precise, real-time information about the size, location, environmental conditions, and resulting damage of an event like a flood or wildfire as well as the location and numbers of emergency responders and other resources contributes directly to the effectiveness of disaster mitigation. The need for such information is also evident when responding to homeland security threats, such as a terrorist attack. Recognizing the value of its geospatial information resources for this and other purposes, in 1998 Stennis and the state of Mississippi partnered to form what became the Enterprise for Innovative Geospatial Solutions (EIGS) industry cluster, supporting the growth of remote sensing and GIS-based research and business. As part of EIGS, several companies partnered with NASA through dual use and Small Business Innovation Research (SBIR) contracts. Among those was NVision.

  1. Information Measures for Multisensor Systems

    DTIC Science & Technology

    2013-12-11

    permuted to generate spectra that were non- physical but preserved the entropy of the source spectra. Another 1000 spectra were constructed to mimic co...Research Laboratory (NRL) has yielded probabilistic models for spectral data that enable the computation of information measures such as entropy and...22308 Chemical sensing Information theory Spectral data Information entropy Information divergence Mass spectrometry Infrared spectroscopy Multisensor

  2. 28 CFR 25.3 - System information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...

  3. 28 CFR 25.3 - System information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...

  4. 28 CFR 25.3 - System information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...

  5. 28 CFR 25.3 - System information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...

  6. 28 CFR 25.3 - System information.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...

  7. Concept of JINR Corporate Information System

    NASA Astrophysics Data System (ADS)

    Filozova, I. A.; Bashashin, M. V.; Korenkov, V. V.; Kuniaev, S. V.; Musulmanbekov, G.; Semenov, R. N.; Shestakova, G. V.; Strizh, T. A.; Ustenko, P. V.; Zaikina, T. N.

    2016-09-01

    The article presents the concept of JINR Corporate Information System (JINR CIS). Special attention is given to the information support of scientific researches - Current Research Information System as a part of the corporate information system. The objectives of such a system are focused on ensuring an effective implementation and research by using the modern information technology, computer technology and automation, creation, development and integration of digital resources on a common conceptual framework. The project assumes continuous system development, introduction the new information technologies to ensure the technological system relevance.

  8. Data Economics in Army Information Systems

    DTIC Science & Technology

    1989-03-01

    A. These applications include: 2-26 " Matlin , 1979. Matlin assigned dollar measures of value to information systems, based on how closely the system...information systems (e.g., Matlin , 1978). Additional support for this kind of test and evaluation framework has been received from several commands...A-44 TITLE: What is the Value of Investment in Information Systems? ORGANIZATION: Information Systems, Land O’Lakes, Inc. AUTHOR: Matlin , Gerald L

  9. Interactive Development Environments for Information Systems

    PubMed Central

    Wasserman, Anthony I.

    1986-01-01

    Most medical information systems are interactive information systems, since they provide their users with conversational access to data. The design of an interactive information system requires attention to data design, process design, and user interface design so that the resulting system will be easy to use and reliable. This paper describes some automated tools aimed at assisting software designers and developers in creating interactive information systems, with emphasis on the Software through Pictures environment and the User Software Engineering (USE) methodology.

  10. Reservoir Model Information System: REMIS

    NASA Astrophysics Data System (ADS)

    Lee, Sang Yun; Lee, Kwang-Wu; Rhee, Taehyun; Neumann, Ulrich

    2009-01-01

    We describe a novel data visualization framework named Reservoir Model Information System (REMIS) for the display of complex and multi-dimensional data sets in oil reservoirs. It is aimed at facilitating visual exploration and analysis of data sets as well as user collaboration in an easier way. Our framework consists of two main modules: the data access point module and the data visualization module. For the data access point module, the Phrase-Driven Grammar System (PDGS) is adopted for helping users facilitate the visualization of data. It integrates data source applications and external visualization tools and allows users to formulate data query and visualization descriptions by selecting graphical icons in a menu or on a map with step-by-step visual guidance. For the data visualization module, we implemented our first prototype of an interactive volume viewer named REMVR to classify and to visualize geo-spatial specific data sets. By combining PDGS and REMVR, REMIS assists users better in describing visualizations and exploring data so that they can easily find desired data and explore interesting or meaningful relationships including trends and exceptions in oil reservoir model data.

  11. The Information Support System: Management Information for Problem Solving.

    ERIC Educational Resources Information Center

    Mead, Nancy A.

    The Information Support System (ISS) is a management information system developed for the National Drug Education Program (NDEP). The major components of the ISS are: (1) the Project Growth Record which provides a tool for project self-evaluation and for communication between NDEP project officers and project directors; (2) the Quarterly Project…

  12. Managing information systems: an ethical framework and information needs matrix.

    PubMed

    Caputo, R K

    1991-01-01

    This paper urged administrators in human services to attend to values and ethics in the design and implementation of automated information systems. Toward this end, it presented an ethical framework reasserting the primacy of clients as citizens and encouraging the development of client-driven information systems. Finally, the paper presented the rationale for and two examples of an Information Needs Matrix to assist administrators in their deliberations about allocating discretionary resources among functional units within organizations.

  13. Colorado Career Information System. Annual Report.

    ERIC Educational Resources Information Center

    Colorado Univ., Boulder. Colorado Career Information Center.

    Covering the period from October 1, 1975, to September 30, 1976, this annual report contains information on the Colorado Career Information System's (COCIS) administration and organization, information development, delivery vehicle, and marketing and field services. (COCIS is an on-line computerized career information system that has been…

  14. Information Systems: A Strategic Approach.

    ERIC Educational Resources Information Center

    Parker, Sue

    1997-01-01

    This paper, which is intended for individuals responsible for information management at British further education (FE) colleges, describes the attempts by a number of FE institutions to manage their information effectively and provides guidelines for FE institutions to follow when developing their own information management strategy. After a brief…

  15. Multilingual Access for Information Systems.

    ERIC Educational Resources Information Center

    Peters, Carol; Sheridan, Paraic

    With the rapid growth of the global information society, the concept of library has evolved to embrace all kinds of information collections, on all kinds of storage media, and using many different access methods. The users of today's information networks and digital libraries, no longer restricted by geographic or spatial boundaries, want to be…

  16. Expert Systems and Intelligent Information Retrieval.

    ERIC Educational Resources Information Center

    Brooks, H. M.

    1987-01-01

    Explores what an intelligent information retrieval system involves and why expert system techniques might interest system designers. Expert systems research is reviewed with emphasis on components, architecture, and computer interaction, and it is concluded that information retrieval is not an ideal problem domain for expert system application at…

  17. An Expertise Based Energy Information System.

    ERIC Educational Resources Information Center

    Rosenberg, S.

    This paper describes an intelligent decision support system for information on petroleum resources and use currently being designed by the Information Methodology Research Project as the first step in the development of a comprehensive intelligent information system for dealing with energy resources in the United States. The system draws on…

  18. Management Information Systems for Colleges and Universities.

    ERIC Educational Resources Information Center

    Schroeder, Roger G.

    A management information system (MIS) is embedded in the management and operating system of the organization. An MIS exists to provide information for management and operating purposes. The MIS must meet the information needs of management and operating users. The MIS consists of two components--a processor and a data base. Packaged systems have…

  19. Phosphorylation-dependent Pex11p and Fis1p interaction regulates peroxisome division

    PubMed Central

    Joshi, Saurabh; Agrawal, Gaurav; Subramani, Suresh

    2012-01-01

    Peroxisome division is regulated by the conserved peroxin Pex11p. In Saccharomyces cerevisiae (Sc), induction of the phosphoprotein ScPex11p coincides with peroxisome biogenesis. We show that the ScPex11p homologue in Pichia pastoris (PpPex11p) is phosphorylated at serine 173. PpPex11p expression and phosphorylation are induced in oleate and coordinated with peroxisome biogenesis. PpPex11p transits to peroxisomes via the endoplasmic reticulum (ER). PpPex11p is unstable and ER restricted gin pex3Δ and pex19Δ cells, which are impaired in peroxisomal membrane protein biogenesis. In oleate medium, the P. pastoris mutants pex11A (constitutively unphosphorylated; S173A) and pex11D (constitutively phosphorylated; S173D) exhibit juxtaposed elongated peroxisomes (JEPs) and hyperdivided forms, respectively, although protein levels remain unchanged. In contrast with ScPex11p, the ER-to-peroxisome translocation in P. pastoris is phosphorylation independent, and the phosphorylation occurs at the peroxisome. We show that PpPex11p interacts with the peroxisome fission machinery via PpFis1p and is regulated by phosphorylation because PpPex11p and PpPex11Dp interact more strongly with PpFis1p than PpPex11Ap. Neither PpPex11p nor PpFis1p is necessary for peroxisome division in methanol medium. We propose a model for the role of PpPex11p in the regulation of peroxisome division through a phosphorylation-dependent interaction with the fission machinery, providing novel insights into peroxisome morphogenesis. PMID:22337771

  20. Image Information Mining System Evaluation Using Information-Theoretic Measures

    NASA Astrophysics Data System (ADS)

    Daschiel, Herbert; Datcu, Mihai

    2005-12-01

    During the last decade, the exponential increase of multimedia and remote sensing image archives, the fast expansion of the world wide web, and the high diversity of users have yielded concepts and systems for successful content-based image retrieval and image information mining. Image data information systems require both database and visual capabilities, but there is a gap between these systems. Database systems usually do not deal with multidimensional pictorial structures and vision systems do not provide database query functions. In terms of these points, the evaluation of content-based image retrieval systems became a focus of research interest. One can find several system evaluation approaches in literature, however, only few of them go beyond precision-recall graphs and do not allow a detailed evaluation of an interactive image retrieval system. Apart from the existing evaluation methodologies, we aim at the overall validation of our knowledge-driven content-based image information mining system. In this paper, an evaluation approach is demonstrated that is based on information-theoretic quantities to determine the information flow between system levels of different semantic abstraction and to analyze human-computer interactions.

  1. Environmental information system for visualizing environmental impact assessment information.

    PubMed

    Cserny, Angelika; Kovács, Zsófia; Domokos, Endre; Rédey, Akos

    2009-01-01

    The Institute of Environmental Engineering at the University of Pannonia has undertaken the challenge to develop an online environmental information system. This system is able to receive and process the collected environmental data via Internet. The authors have attached importance to the presentation of the data and have included other comprehensible information for laymen as well in order to work out visualisation techniques that are expressive and attract attention for environmental questions through the developed information system. The ways of visualizing physical and chemical parameters of surface water and the effects of motorway construction were examined.

  2. Developing a Management Information System.

    ERIC Educational Resources Information Center

    Yost, Michael

    This paper is based on the assumption that in shaping academic strategies for long-range planning purposes, educational institutions must be able to gather adequate information on which to base administrative decisions. Information on how the institution has operated in the past as well as how it is currently operating are critical items for valid…

  3. Survey of Alaska Information Systems.

    ERIC Educational Resources Information Center

    Allen, Anda; Sokolov, Barbara J.

    This survey by the Arctic Environmental Information and Data Center at the University of Alaska identifies and describes information and data collections within Alaskan libraries and agency offices which pertain to fish and wildlife or their habitat. Included in the survey are descriptions of the location, characteristics, and availability of…

  4. Science Information Systems Newsletter, issue 28

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The purpose of the Information Systems Newsletter is to inform the space science and applications research community about information systems development and to promote coordination and collaboration by providing a forum for communication. This quarterly publication focuses on programs sponsored by the Information Systems Branch in support of NASA's Office of Space Science. Articles of interest for other programs and agencies are presented as well. The April 1993 issue is presented.

  5. Enterprise Energy Information Systems and Management

    DTIC Science & Technology

    2011-12-01

    surveillance system for protecting critical infrastructure Video analysis and automated intruder detection /alert Enhanced monitoring with simultaneous...Cognitive Energy Management System (CEMS) • Augment standard building automation systems with intelligent control through localized sensors and a...ACTIVITY NAME Enterprise Energy Information Systems and Management Jeffrey Johnson, NDW Chief Information Officer ESTCP Conference Dec 1, 2011

  6. TWRS information locator database system design description

    SciTech Connect

    Knutson, B.J.

    1996-09-13

    This document gives an overview and description of the Tank Waste Remediation System (TWRS) Information Locator Database (ILD)system design. The TWRS ILD system is an inventory of information used in the TWRS Systems Engineering process to represent the TWRS Technical Baseline. The inventory is maintained in the form of a relational database developed in Paradox 4.5.

  7. Information management challenges of the EOS Data and Information System

    NASA Technical Reports Server (NTRS)

    Mcdonald, Kenneth R.; Blake, Deborah J.

    1991-01-01

    An overview of the current information management concepts that are embodied in the plans for the Earth Observing System Data and Information System (EOSDIS) is presented, and some of the technology development and application areas that are envisioned to be particularly challenging are introduced. The Information Management System (IMS) is the EOSDIS element that provides the primary interface between the science users and the data products and services of EOSDIS. The goals of IMS are to define a clear and complete set of functional requirements and to apply innovative methods and technologies to satisfy them. The information management functions are described in detail, and some applicable technolgies are discussed. Some of the general issues affecting the successful development and operation of the information management element are addressed.

  8. Information management challenges of the EOS Data and Information System

    NASA Technical Reports Server (NTRS)

    Mcdonald, Kenneth R.; Blake, Deborah J.

    1991-01-01

    An overview of the current information management concepts that are embodied in the plans for the Earth Observing System Data and Information System (EOSDIS) is presented, and some of the technology development and application areas that are envisioned to be particularly challenging are introduced. The Information Management System (IMS) is the EOSDIS element that provides the primary interface between the science users and the data products and services of EOSDIS. The goals of IMS are to define a clear and complete set of functional requirements and to apply innovative methods and technologies to satisfy them. The information management functions are described in detail, and some applicable technolgies are discussed. Some of the general issues affecting the successful development and operation of the information management element are addressed.

  9. A survey of chemical information systems

    NASA Technical Reports Server (NTRS)

    Dominick, Wayne D. (Editor); Shaikh, Aneesa Bashir

    1985-01-01

    A survey of the features, functions, and characteristics of a fairly wide variety of chemical information storage and retrieval systems currently in operation is given. The types of systems (together with an identification of the specific systems) addressed within this survey are as follows: patents and bibliographies (Derwent's Patent System; IFI Comprehensive Database; PULSAR); pharmacology and toxicology (Chemfile; PAGODE; CBF; HEEDA; NAPRALERT; MAACS); the chemical information system (CAS Chemical Registry System; SANSS; MSSS; CSEARCH; GINA; NMRLIT; CRYST; XTAL; PDSM; CAISF; RTECS Search System; AQUATOX; WDROP; OHMTADS; MLAB; Chemlab); spectra (OCETH; ASTM); crystals (CRYSRC); and physical properties (DETHERM). Summary characteristics and current trends in chemical information systems development are also examined.

  10. Information for Successful Interaction with Autonomous Systems

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Johnson, Kathy A.

    2003-01-01

    Interaction in heterogeneous mission operations teams is not well matched to classical models of coordination with autonomous systems. We describe methods of loose coordination and information management in mission operations. We describe an information agent and information management tool suite for managing information from many sources, including autonomous agents. We present an integrated model of levels of complexity of agent and human behavior, which shows types of information processing and points of potential error in agent activities. We discuss the types of information needed for diagnosing problems and planning interactions with an autonomous system. We discuss types of coordination for which designs are needed for autonomous system functions.

  11. Information Systems; Modern Health Care and Medical Information.

    ERIC Educational Resources Information Center

    Brandejs, J. F., And Others

    1975-01-01

    To effectively handle changes in health policy and health information, new designs and applications of automation are explored. Increased use of computer-based information systems in health care could serve as a means of control over the costs of developing more comprehensive health service, with applications increasing not only the automation of…

  12. Information-Systems Data-Flow Diagram

    NASA Technical Reports Server (NTRS)

    Blosiu, J. O.

    1983-01-01

    Single form presents clear picture of entire system. Form giving relational review of data flow well suited to information system planning, analysis, engineering, and management. Used to review data flow for developing system or one already in use.

  13. Information-Systems Data-Flow Diagram

    NASA Technical Reports Server (NTRS)

    Blosiu, J. O.

    1983-01-01

    Single form presents clear picture of entire system. Form giving relational review of data flow well suited to information system planning, analysis, engineering, and management. Used to review data flow for developing system or one already in use.

  14. Designing control system information models

    NASA Technical Reports Server (NTRS)

    Panin, K. I.; Zinchenko, V. P.

    1973-01-01

    Problems encountered in modeling information models are discussed, Data cover condition, functioning of the object of control, and the environment involved in the control. Other parameters needed for the model include: (1) information for forming an image of the real situation, (2) data for analyzing and evaluating an evolving situation, (3) planning actions, and (4) data for observing and evaluating the results of model realization.

  15. School Management Information Systems in Primary Schools

    ERIC Educational Resources Information Center

    Demir, Kamile

    2006-01-01

    Developments in information technologies have been impacting upon educational organizations. Principals have been using management information systems to improve the efficiency of administrative services. The aim of this research is to explore principals' perceptions about management information systems and how school management information…

  16. Developing a Career Information System: Final Report.

    ERIC Educational Resources Information Center

    McKinlay, Bruce

    The report reviews three years of progress toward implementing the Career Information System (CIS), a statewide interagency consortium that provides current labor market and educational information in usable forms to students and clients and assists in the integration of such information into schools and social agencies in Oregon. The system's…

  17. Gamified Android Based Academic Information System

    ERIC Educational Resources Information Center

    Setiana, Henry; Hansun, Seng

    2017-01-01

    Student is often lazy when it comes to studying, and how to motivate student was one of the problem in the educational world. To overcome the matters, we will implement the gamification method into an Academic Information System. Academic Information System is a software used for providing information and arranging administration which connected…

  18. An Information System in the Private Sector.

    ERIC Educational Resources Information Center

    Gordon, Arlene R.; And Others

    1983-01-01

    The article describes how the New York Association for the Blind (The Lighthouse) studied its information needs and further systematized information collection, retrieval, and use for internal case management and external information exchange with human service agencies by means of a computerized client information system. (Author)

  19. Information technology security system engineering methodology

    NASA Technical Reports Server (NTRS)

    Childs, D.

    2003-01-01

    A methodology is described for system engineering security into large information technology systems under development. The methodology is an integration of a risk management process and a generic system development life cycle process. The methodology is to be used by Security System Engineers to effectively engineer and integrate information technology security into a target system as it progresses through the development life cycle. The methodology can also be used to re-engineer security into a legacy system.

  20. Information technology security system engineering methodology

    NASA Technical Reports Server (NTRS)

    Childs, D.

    2003-01-01

    A methodology is described for system engineering security into large information technology systems under development. The methodology is an integration of a risk management process and a generic system development life cycle process. The methodology is to be used by Security System Engineers to effectively engineer and integrate information technology security into a target system as it progresses through the development life cycle. The methodology can also be used to re-engineer security into a legacy system.

  1. Integration of hospital information systems, operative and peri-operative information systems, and operative equipment into a single information display.

    PubMed

    Meyer, Mark; Levine, Wilton C; Brzezinski, Philip; Robbins, Jeffrey; Lai, Fuji; Spitz, Gabriel; Sandberg, Warren S

    2005-01-01

    The integration of disparate information systems in the operative environment allows access to information that is typically unseen or unused. Through a collaborative effort, a variety of information systems and surgical equipment are being integrated. This provides improved context-sensitive information display and decision support and improved access to information to improve workflow, safety and visualization of information that was previously unattainable.

  2. The role of FIS in trans activation of stable RNA operons of E. coli.

    PubMed

    Nilsson, L; Vanet, A; Vijgenboom, E; Bosch, L

    1990-03-01

    The thrU(tufB) operon of Escherichia coli is endowed with a cis-acting region upstream of the promoter, designated UAS for Upstream Activator Sequence. A protein fraction has been isolated that binds specifically to DNA fragments of the UAS, thus forming three protein-DNA complexes corresponding to three binding sites on the UAS. It stimulates in vitro transcription of the operon by facilitating the binding of the RNA polymerase to the promoter. All three protein-DNA complexes contain one and the same protein. Dissociation constants for the three complexes have been determined, the lowest being in the sub-nanomolar range. The protein also binds to the UAS of the tyrT operon and to the UAS upstream of the P1 promoter of the rrnB operon, suggesting that transcription of the three operons, if not of more stable RNA operons, is activated by a common trans activator. We demonstrate that the E.coli protein FIS (Factor for Inversion Stimulation) also binds to the UAS of the thrU(tufB) operon forming three protein-DNA complexes. A burst of UAS- and FIS-dependent promoter activity is observed after reinitiation of growth of stationary cultures in fresh medium.

  3. Trip Information Log Tracking System

    SciTech Connect

    Jones, Jeffrey F.

    1992-06-23

    The system is focused on the Employee Business Travel Event. The system must be able to CRUD (Create, Retrieve, Update, Delete) instances of the Travel Event as well as the ability to CRUD frequent flyer milage associated with airline travel. Additionally the system must provide for a compliance reporting system to monitor reductions in travel costs and lost opportunity costs (i.e., not taking advantage of business class or 7 day advance tickets).

  4. Systems Suitable for Information Professionals.

    ERIC Educational Resources Information Center

    Blair, John C., Jr.

    1983-01-01

    Describes computer operating systems applicable to microcomputers, noting hardware components, advantages and disadvantages of each system, local area networks, distributed processing, and a fully configured system. Lists of hardware components (disk drives, solid state disk emulators, input/output and memory components, and processors) and…

  5. Environmental remediation and waste management information systems

    SciTech Connect

    Harrington, M.W.; Harlan, C.P.

    1993-12-31

    The purpose of this paper is to document a few of the many environmental information systems that currently exist worldwide. The paper is not meant to be a comprehensive list; merely a discussion of a few of the more technical environmental database systems that are available. Regulatory databases such as US Environmental Protection Agency`s (EPA`s) RODS (Records of Decision System) database [EPA, 1993] and cost databases such as EPA`s CORA (Cost of Remedial Action) database [EPA, 1993] are not included in this paper. Section 2 describes several US Department of Energy (DOE) Environmental Restoration and Waste Management (EM) information systems and databases. Section 3 discusses several US EPA information systems on waste sites and technologies. Section 4 summarizes a few of the European Community environmental information systems, networks, and clearinghouses. And finally, Section 5 provides a brief overview of Geographical Information Systems. Section 6 contains the references, and the Appendices contain supporting information.

  6. The Czechoslovak Computer Information System ASTI

    ERIC Educational Resources Information Center

    Fendrych, Miroslav; Fogl, Ing. Jiri

    1971-01-01

    Discussed is the Czechoslovak program of State Information Policy which aims at the construction of a unified, integrated national system of scientific, technological and economic information. (Author/SJ)

  7. The Bilingual Test Information System.

    ERIC Educational Resources Information Center

    RMC Research Corp., Hampton, NH.

    A resource is presented for those who work in bilingual education and who are involved in test selection. Initial information is provided regarding tests that might be used for student identification, placement and diagnosis, progress monitoring, exiting decisions, and program evaluation purposes. No endorsement or recommendation is implied and no…

  8. Dialectical Learning in Information Systems

    ERIC Educational Resources Information Center

    Reed, Adam

    2008-01-01

    The classical dialectical (study partner) learning method of Greek and Hellenistic antiquity remains the traditional learning method of Jewish religious and cultural studies, and enjoys widespread informal use by students in some American universities. The cognitive advantages of dialectical study have led to its adoption as a powerful, general…

  9. Top Four Trends in Student Information Systems

    ERIC Educational Resources Information Center

    Weathers, Robert

    2013-01-01

    The modern student information systems (SIS) is a powerful administrative tool with robust functionality. As such, it is essential that school and district administrators consider the top trends in modern student information systems before going forward with system upgrades or new purchases. These trends, described herein, are: (1) Support for…

  10. Top Four Trends in Student Information Systems

    ERIC Educational Resources Information Center

    Weathers, Robert

    2013-01-01

    The modern student information systems (SIS) is a powerful administrative tool with robust functionality. As such, it is essential that school and district administrators consider the top trends in modern student information systems before going forward with system upgrades or new purchases. These trends, described herein, are: (1) Support for…

  11. Transforming Legacy Systems to Obtain Information Superiority

    DTIC Science & Technology

    2001-01-01

    is imperative that innovative technologies be developed to enable legacy weapon systems to exploit the information revolution, achieve information ... dominance , and meet the required operational tempo. This paper presents an embedded-system architecture, open system middleware services, and a software

  12. Michigan Occupational Information System Final Evaluation Report.

    ERIC Educational Resources Information Center

    Gordon, Eric M.; And Others

    An evaluation of the Michigan Occupational Information System (MOIS) was conducted. (The MOIS is a system designed to provide reliable and current career information organized in a readily accessible system for individuals involved in career exploration and decision making.) Three types of survey instruments (site, staff, and client surveys) were…

  13. Three Ontario Boards Testing Computerized Information System

    ERIC Educational Resources Information Center

    Sch Progr, 1970

    1970-01-01

    Pilot for computerizing financial information may also be used for personnel, students, facilities, curriculum and instruction. The project uses the Generalized Education Management System software (GEMS) developed by Oregon Total Information System (OTIS) and modified by AGT Data Systems Ltd. of Toronto. (DE)

  14. Applications of Clustering to Information System Design.

    ERIC Educational Resources Information Center

    Stanfel, Larry E.

    1983-01-01

    Describes methods for effecting the partition of information systems consisting of many components and interconnections into subsystems which are later made to interface with one another achieving an overall system. Clustering algorithms for the specific case of information systems are obtained and exemplified. Twenty-seven references are…

  15. Management Information Systems: Applications to Educational Administration.

    ERIC Educational Resources Information Center

    Witkin, Belle Ruth

    An orientation to management information systems (MIS) is offered which presents information about MIS in the context of public education and suggests some considerations that should be taken into account in designing and operating such systems. MIS is defined as a set of operating procedures that act as a control system to automatically provide…

  16. Implementation of Alabama Resources Information System, ARIS

    NASA Technical Reports Server (NTRS)

    Herring, B. E.

    1978-01-01

    Development of ARIS - Alabama Resources Information System is summarized. Development of data bases, system simplification for user access, and making information available to personnel having a need to use ARIS or in the process of developing ARIS type systems are discussed.

  17. Applications of Clustering to Information System Design.

    ERIC Educational Resources Information Center

    Stanfel, Larry E.

    1983-01-01

    Describes methods for effecting the partition of information systems consisting of many components and interconnections into subsystems which are later made to interface with one another achieving an overall system. Clustering algorithms for the specific case of information systems are obtained and exemplified. Twenty-seven references are…

  18. Flight Projects Office Information Systems Testbed (FIST)

    NASA Technical Reports Server (NTRS)

    Liggett, Patricia

    1991-01-01

    Viewgraphs on the Flight Projects Office Information Systems Testbed (FIST) are presented. The goal is to perform technology evaluation and prototyping of information systems to support SFOC and JPL flight projects in order to reduce risk in the development of operational data systems for such projects.

  19. Information flow in heterogeneously interacting systems.

    PubMed

    Yamaguti, Yutaka; Tsuda, Ichiro; Takahashi, Yoichiro

    2014-02-01

    Motivated by studies on the dynamics of heterogeneously interacting systems in neocortical neural networks, we studied heterogeneously-coupled chaotic systems. We used information-theoretic measures to investigate directions of information flow in heterogeneously coupled Rössler systems, which we selected as a typical chaotic system. In bi-directionally coupled systems, spontaneous and irregular switchings of the phase difference between two chaotic oscillators were observed. The direction of information transmission spontaneously switched in an intermittent manner, depending on the phase difference between the two systems. When two further oscillatory inputs are added to the coupled systems, this system dynamically selects one of the two inputs by synchronizing, selection depending on the internal phase differences between the two systems. These results indicate that the effective direction of information transmission dynamically changes, induced by a switching of phase differences between the two systems.

  20. A Personalized Health Information Retrieval System

    PubMed Central

    Wang, Yunli; Liu, Zhenkai

    2005-01-01

    Consumers face barriers when seeking health information on the Internet. A Personalized Health Information Retrieval System (PHIRS) is proposed to recommend health information for consumers. The system consists of four modules: (1) User modeling module captures user’s preference and health interests; (2) Automatic quality filtering module identifies high quality health information; (3) Automatic text difficulty rating module classifies health information into professional or patient educational materials; and (4) User profile matching module tailors health information for individuals. The initial results show that PHIRS could assist consumers with simple search strategies. PMID:16779435

  1. An information typology for understanding living systems.

    PubMed

    Banathy, B A

    1998-04-01

    It is argued that we can improve our understanding of living systems by focusing on their informational processes. Recent developments, primarily in evolutionary biology, cybernetics and systems theory, suggest that informational processes are of at least two, and probably three, different types; and that the interaction of these types can be seen as a basis for the self-construction of living systems. Following the work of Csanyi and Kampis, a distinction is drawn between referential and nonreferential information. This typology is further extended to include statereferential information. The statereferential type serves to lend stability to informational arrangements (organization) that are viable so that they may be propagated in space and time.

  2. Library Information-Processing System

    NASA Technical Reports Server (NTRS)

    1985-01-01

    System works with Library of Congress MARC II format. System composed of subsystems that provide wide range of library informationprocessing capabilities. Format is American National Standards Institute (ANSI) format for machine-readable bibliographic data. Adaptable to any medium-to-large library.

  3. Compressive Information Extraction: A Dynamical Systems Approach

    DTIC Science & Technology

    2016-01-24

    AFRL-AFOSR-VA-TR-2016-0097 Compressive Information Extraction A Dynamical Systems Approach Mario Sznaier NORTHEASTERN UNIVERSITY Final Report 02/09...Final Performance 3. DATES COVERED (From - To) 01-06-2012 to 31-05-2015 4. TITLE AND SUBTITLE Compressive Information Extraction A Dynamical Systems ... information extraction, hybrid system identification 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER OF PAGES 19a.  NAME OF

  4. Modeling risk in distributed healthcare information systems.

    PubMed

    Maglogiannis, Ilias; Zafiropoulos, Elias

    2006-01-01

    This paper presents a modeling approach for performing a risk analysis study of networked healthcare information systems. The proposed method is based on CRAMM for studying the assets, threats and vulnerabilities of the distributed information system, and models their interrelationships using Bayesian networks. The most critical events are identified and prioritized, based on "what - if" studies of system operation. The proposed risk analysis framework has been applied to a healthcare information network operating in the North Aegean Region in Greece.

  5. ROTC Cadet Information System (RCIS)

    DTIC Science & Technology

    1988-01-01

    other database files are used to support the master file information. The cadet master record can be thought of as the parent record for the cadet pay...Intrview Inforution CaRER FRNU 15/15/89 3.6 CORPS SGT MAJOR 11/9/87 FAI -) VICE CWR FOR NATO FORCES IN EUROPE 0-v S,’,, 0- =" -- - ’ Query Input Screen

  6. Multifunctional Information Distribution System (MIDS)

    DTIC Science & Technology

    2013-12-01

    Procurement Unit Cost BA - Budget Authority/Budget Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development...Award Critical Design Review (MID ... LVT -LVT(2) r,... First EMD Terminal Delivery LVT LVT(3) lt:>e LVT(2) -Initial Carrier Suitability •:oe IOT ...1998 LVT(2) MAY 1998 MAY 1998 NOV 1998 MAY 1998 Initial Carrier Suitability NOV 1998 NOV 1998 MAY 1999 NOV 1998 IOT &E Complete LVT(3) JUL 1999 JUL

  7. Geographic Information Systems: A Primer

    DTIC Science & Technology

    1990-10-01

    emulsion -based (film) or digital. Information is obtained from a wide range of the electromagnetic spectrum, from ultraviolet to microwave . When... microwave . Imagery is manually or digitally interpreted. For GIS, images can be classified into thematic categories, rendering data into a map or into a...a dedicated project of circumscribed scope. Petroleum companies are interested in oil exploration and thus employ GIS for specific purposes. The

  8. Enterprise Information System Integration Technology

    NASA Astrophysics Data System (ADS)

    Tanaka, Tetsuo; Yumoto, Masaki; Itsuki, Rei

    In the current rapidly changing business environment, companies need to be efficient and agile to survive and thrive. That is why flexible systems integration is urgent and crucial concern for any enterprise. For the meanwhile, systems integration technology is getting more complicated, and middleware types are beginning blur for decades. We sort system integration into four different types, “Delayed Federation", “Real-time Federation", “Delayed Integration", and “Real-time Integration". We also outline appropriate technology and architecture for each type.

  9. Analysis of information systems for hydropower operations

    NASA Technical Reports Server (NTRS)

    Sohn, R. L.; Becker, L.; Estes, J.; Simonett, D.; Yeh, W. W. G.

    1976-01-01

    The operations of hydropower systems were analyzed with emphasis on water resource management, to determine how aerospace derived information system technologies can increase energy output. Better utilization of water resources was sought through improved reservoir inflow forecasting based on use of hydrometeorologic information systems with new or improved sensors, satellite data relay systems, and use of advanced scheduling techniques for water release. Specific mechanisms for increased energy output were determined, principally the use of more timely and accurate short term (0-7 days) inflow information to reduce spillage caused by unanticipated dynamic high inflow events. The hydrometeorologic models used in predicting inflows were examined to determine the sensitivity of inflow prediction accuracy to the many variables employed in the models, and the results used to establish information system requirements. Sensor and data handling system capabilities were reviewed and compared to the requirements, and an improved information system concept outlined.

  10. Manpower management information system /MIS/

    NASA Technical Reports Server (NTRS)

    Gravette, M. C.; King, W. L.

    1971-01-01

    System of programs capable of building and maintaining data bank provides all levels of management with regular manpower evaluation reports and data source for special management exercises on manpower.

  11. Informational analysis involving application of complex information system

    NASA Astrophysics Data System (ADS)

    Ciupak, Clébia; Vanti, Adolfo Alberto; Balloni, Antonio José; Espin, Rafael

    The aim of the present research is performing an informal analysis for internal audit involving the application of complex information system based on fuzzy logic. The same has been applied in internal audit involving the integration of the accounting field into the information systems field. The technological advancements can provide improvements to the work performed by the internal audit. Thus we aim to find, in the complex information systems, priorities for the work of internal audit of a high importance Private Institution of Higher Education. The applied method is quali-quantitative, as from the definition of strategic linguistic variables it was possible to transform them into quantitative with the matrix intersection. By means of a case study, where data were collected via interview with the Administrative Pro-Rector, who takes part at the elaboration of the strategic planning of the institution, it was possible to infer analysis concerning points which must be prioritized at the internal audit work. We emphasize that the priorities were identified when processed in a system (of academic use). From the study we can conclude that, starting from these information systems, audit can identify priorities on its work program. Along with plans and strategic objectives of the enterprise, the internal auditor can define operational procedures to work in favor of the attainment of the objectives of the organization.

  12. Majoring in Information Systems: Reasons Why Students Select (or Not) Information Systems as a Major

    ERIC Educational Resources Information Center

    Snyder, Johnny; Slauson, Gayla Jo

    2014-01-01

    Filling the pipeline for information systems workers is critical in the information era. Projected growth rates for jobs requiring information systems expertise are significantly higher than the projected growth rates for other jobs. Why then do relatively few students choose to major in information systems? This paper reviews survey results from…

  13. International Aircraft Operator Information System

    DTIC Science & Technology

    1993-04-01

    engine/series to the EICCODE exception list. It only allows UPDATE on AICCODE field. The top portion of the screen displays information in table F107 ... F107 ASAS Engine Xrf F108 ASAS Aic Xrf Fl 1 1 Operators B-2 Jetnet JNO 1 Corporate fleet JN02 Country Xrf JN03 ASAS speedo table ( subset of NACI for...Link to F107 25 EST AGE CHAR 1 Y Estimated Age of Aircraft 26 FLIGHT HRS NUMBER 22 9 Y Flying Hours 27 INFLUENCE CHAR 2 Y Influence 28 LUPDATE DATE

  14. Policy enabled information sharing system

    DOEpatents

    Jorgensen, Craig R.; Nelson, Brian D.; Ratheal, Steve W.

    2014-09-02

    A technique for dynamically sharing information includes executing a sharing policy indicating when to share a data object responsive to the occurrence of an event. The data object is created by formatting a data file to be shared with a receiving entity. The data object includes a file data portion and a sharing metadata portion. The data object is encrypted and then automatically transmitted to the receiving entity upon occurrence of the event. The sharing metadata portion includes metadata characterizing the data file and referenced in connection with the sharing policy to determine when to automatically transmit the data object to the receiving entity.

  15. Uniform Library Information Systems in Yugoslavia.

    ERIC Educational Resources Information Center

    Zivkovic, Bogomila

    1979-01-01

    The process followed by Yugoslavia in developing a national interdisciplinary information system included surveys of existing library practices, identification of potential databases, processing of library materials, production of national bibliographies, production of catalogs, and use of the system. (FM)

  16. Sandia Explosive Inventory and Information System

    SciTech Connect

    Clements, D.A.

    1994-08-01

    The Explosive Inventory and Information System (EIS) is being developed and implemented by Sandia National Laboratories (SNL) to incorporate a cradle to grave structure for all explosives and explosive containing devices and assemblies at SNL from acquisition through use, storage, reapplication, transfer or disposal. The system does more than track all material inventories. It provides information on material composition, characteristics, shipping requirements; life cycle cost information, plan of use; and duration of ownership. The system also provides for following the processes of explosive development; storage review; justification for retention; Resource, Recovery and Disposition Account (RRDA); disassembly and assembly; and job description, hazard analysis and training requirements for all locations and employees involved with explosive operations. In addition, other information systems will be provided through the system such as the Department of Energy (DOE) and SNL Explosive Safety manuals, the Navy`s Department of Defense (DoD) Explosive information system, and the Lawrence Livermore National Laboratories (LLNL) Handbook of Explosives.

  17. Remote sensing and geographically based information systems

    NASA Technical Reports Server (NTRS)

    Cicone, R. C.

    1977-01-01

    The incorporation of remotely sensed digital data in a computer based information system is seen to be equivalent to the incorporation of any other spatially oriented layer of data. The growing interest in such systems indicates a need to develop a generalized geographically oriented data base management system that could be made commercially available for a wide range of applications. Some concepts that distinguish geographic information systems were reviewed, and a simple model which can serve as a conceptual framework for the design of a generalized geographic information system was examined.

  18. Security in the management of information systems.

    PubMed

    Huston, T L; Huston, J L

    1998-06-01

    Although security technology exists in abundance in health information management systems, the implementation of that technology is often lacking. This lack of implementation can be heavily affected by the attitudes and perceptions of users and management, the "people part" of systems. Particular operational, organizational, and economic factors must be addressed along with employment of security objectives and accountability. Unique threats, as well as controls, pervade the use of microcomputer-based systems as these systems permeate health care information management.

  19. Information Systems and Business Communication.

    ERIC Educational Resources Information Center

    Beswick, Raymond W., Ed.; Williams, Alfred B., Ed.

    Intended to provide orientation about the integration of business communication, business systems, and the researching and teaching of business communication, this books offers articles on a variety of topics concerning business communication. Titles of the articles and their authors are as follows: (1) "Office Technology: Voice Store-and-Forward"…

  20. Next Generation Information Systems Architectures

    DTIC Science & Technology

    2008-07-01

    Orthogonal Golay Sequences and Application to Channel Estimation of MIMO -OFDM Systems," Vol. 56, No. 1, January 2008, pp. 27-31 "AANET: Aerial Ad-hoc...increasingly evident that the growth of wireless local access networks (WLANs) based on 802.11x standards like Wi-Fi will soon be massive and widespread

  1. Information retrieval and display system

    NASA Technical Reports Server (NTRS)

    Groover, J. L.; King, W. L.

    1977-01-01

    Versatile command-driven data management system offers users, through simplified command language, a means of storing and searching data files, sorting data files into specified orders, performing simple or complex computations, effecting file updates, and printing or displaying output data. Commands are simple to use and flexible enough to meet most data management requirements.

  2. Occupational Information Data System: Final Report.

    ERIC Educational Resources Information Center

    New Hampshire Univ., Durham.

    The one-year extension (1973-74) of the Occupational Information Improvement Project (OIIP) was implemented to provide recommendations for the continuation or termination of the Occupational Information Data System of the New Hampshire VIEW (Vital Information for Education and Work) program. A survey was administered to 120 schools identified in…

  3. Establishing Information Security Systems via Optical Imaging

    DTIC Science & Technology

    2015-08-11

    to encrypt and authenticate information for data/images storage and transmission, including optical systems for secured information. 15. SUBJECT...TERMS Optical Imaging, Optical Cryptosystems , Diffractive Imaging, Optical Encryption 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18...sector). The main objective is to develop optical imaging technologies to encrypt and authenticate information for data/images storage and

  4. Information transfer in the National Airspace System

    NASA Technical Reports Server (NTRS)

    Lee, Alfred T.

    1988-01-01

    An informal overview is given of the work in progress and the planned work in the area of information transfer that specifically addresses human factors issues in National Airspace System (NAS). The issues of how weather information will be displayed on the flight deck, the development of appropriate decision making technology, and digital datalink transmission are also briefly discussed.

  5. Multisensor robotic system for autonomous space maintenance and repair

    NASA Technical Reports Server (NTRS)

    Abidi, M. A.; Green, W. L.; Chandra, T.; Spears, J.

    1988-01-01

    The feasibility of realistic autonomous space manipulation tasks using multisensory information is demonstrated. The system is capable of acquiring, integrating, and interpreting multisensory data to locate, mate, and demate a Fluid Interchange System (FIS) and a Module Interchange System (MIS). In both cases, autonomous location of a guiding light target, mating, and demating of the system are performed. Implemented visio-driven techniques are used to determine the arbitrary two-dimensional position and orientation of the mating elements as well as the arbitrary three-dimensional position and orientation of the light targets. A force/torque sensor continuously monitors the six components of force and torque exerted on the end-effector. Both FIS and MIS experiments were successfully accomplished on mock-ups built for this purpose. The method is immune to variations in the ambient light, in particular because of the 90-minute day-night shift in space.

  6. Multisensor robotic system for autonomous space maintenance and repair

    NASA Technical Reports Server (NTRS)

    Abidi, M. A.; Green, W. L.; Chandra, T.; Spears, J.

    1988-01-01

    The feasibility of realistic autonomous space manipulation tasks using multisensory information is demonstrated. The system is capable of acquiring, integrating, and interpreting multisensory data to locate, mate, and demate a Fluid Interchange System (FIS) and a Module Interchange System (MIS). In both cases, autonomous location of a guiding light target, mating, and demating of the system are performed. Implemented visio-driven techniques are used to determine the arbitrary two-dimensional position and orientation of the mating elements as well as the arbitrary three-dimensional position and orientation of the light targets. A force/torque sensor continuously monitors the six components of force and torque exerted on the end-effector. Both FIS and MIS experiments were successfully accomplished on mock-ups built for this purpose. The method is immune to variations in the ambient light, in particular because of the 90-minute day-night shift in space.

  7. Wind energy systems information user study

    SciTech Connect

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1981-01-01

    This report describes the results of a series of telephone interviews with potential users of information on wind energy conversion. These interviews, part of a larger study covering nine different solar technologies, attempted to identify: the type of information each distinctive group of information users needed, and the best way of getting information to that group. Groups studied include: wind energy conversion system researchers; wind energy conversion system manufacturer representatives; wind energy conversion system distributors; wind turbine engineers; utility representatives; educators; county agents and extension service agents; and wind turbine owners.

  8. Hospital information system survey in qatar.

    PubMed

    Al-Ali, Rashid; Reti, Shane; Feldman, Henry; Safran, Charles; Niaz, Rashid; Erskine, Alistair; Elmagarmid, Ahmed; Al-Musleh, Abdulwahab

    2013-01-01

    Healthcare can be enhanced by the effective use of information technology to improve the quality and safety of care and many healthcare providers are adopting advanced health information technology to improve their healthcare delivery process. Qatar is a relatively young Middle Eastern country with an ambitious and progressive national strategy to develop its healthcare system, including an advanced e-health infrastructure delivering the right medical information at the right time to clinicians and patients. To assess the effectiveness of such programs, it is important to have a pre-intervention baseline from which comparisons, performance against target measures and forward thinking strategic planning can be grounded. This study presents the first published campus wide survey of Hospital Information Systems in large public and private hospitals in Qatar. To qualitatively assess and describe the current state of Hospital Information Systems in large hospitals in Qatar, and to establish a baseline or reference point for Qatar's readiness for, and adoption of Hospital Information Systems.

  9. Information Systems Vulnerability: A Systems Analysis Perspective

    DTIC Science & Technology

    1996-06-01

    viewgraph, video ,electronicposting(Internet, WorldWideWeb, external network), etc.) Information S stems Vulnerability : A S st . .Ctlve Sandiaauthor...12614 (8815) for videos ; Interactive Media 12616 (8815) for multimedia products or technical artwork; Corporate Exhibits 12613 (8815) for exhibits.) DOE...Conference Paper (3 copies) ❑ Exhibit/Display/Poster ❑ Publication ❑ SlidesNiewgraphs ❑ .Audio/ Video /Film ❑ Electronic Posting ❑ Journal Article

  10. A Prototype Climate Information System

    DTIC Science & Technology

    1993-01-01

    Access to the NCDS could also support some of the operational needs of naval bases, such as NEOC. 2. CLICOM CLICOM is a climatic data processing system...developed by the NCDC under a WMO contract (McGuirk and Llanso, 1989). CLICOM is designed primarily for use in developing countries, by personnel with...little technical training. CLICOM currently is used in 37 countries, including 35 sites in the USA. CLICOM software runs on an IBM PC and manuals

  11. Academic Information Systems: From Segregation to Integration.

    ERIC Educational Resources Information Center

    Bernbom, Gerald; And Others

    1992-01-01

    Through integration of administrative information systems across diverse technology platforms and opening access to institutional data, Indiana University has begun to expand the concept of academic information systems. The university's experience has resulted in conclusions and guidelines for other institutions to use in AIS planning and…

  12. Compatibility Issues Affecting Information Systems and Services.

    ERIC Educational Resources Information Center

    Lancaster, F. Wilfrid; Smith, Linda C.

    This UNISIST publication discusses issues related to the compatibility and standardization of bibliograpic records, index languages, software, hardware, and other information systems and services. Following an executive summary, definitions of terms, and other introductory material, existing information systems with common standards are briefly…

  13. Information Systems Curricula: A Fifty Year Journey

    ERIC Educational Resources Information Center

    Longenecker, Herbert E., Jr.; Feinstein, David; Clark, Jon D.

    2013-01-01

    This article presents the results of research to explore the nature of changes in skills over a fifty year period spanning the life of Information Systems model curricula. Work begun in 1999 was expanded both backwards in time, as well as forwards to 2012 to define skills relevant to Information Systems curricula. The work in 1999 was based on job…

  14. ENVIRONMENTAL INFORMATION MANAGEMENT SYSTEM (EIMS) FACT SHEET

    EPA Science Inventory

    The purpose of the fact sheet is to provide information about the US EPA Office of Research and Developments Environmental Information Management System. The fact sheet indicates the type of records that are in EIMS, systems that are integrated with EIMS as well as some highligh...

  15. Improving Ohio's Education Management Information System (EMIS).

    ERIC Educational Resources Information Center

    Ohio State Legislative Office of Education Oversight, Columbus.

    Due to legislative mandate, the Ohio Department of Education (ODE) was required to develop a system (the Education Management Information System) that would increase the amount of information available to state-level policy makers and the public. Some recommendations for improving the function of EMIS are offered in this report. The text provides…

  16. Performance Information Management System (PIMS) Communication

    DTIC Science & Technology

    1992-10-15

    AD-A267 040 AD 14IPR NO: 92M•2501 TITLE: PERFORMANCE INFORMATION MANAGEMENT SYSTEM (PIMS) COMMUNICATION V G ,c¶• PRINCIPAL INVESTIGATOR: Kathryn P...Performance Information Management System (PIMS) MIPR No. Communication 92MM2501 6. AUTHOR(S) Kathryn P. Winter 7. PERFORMING ORGANIZATION NAME(S) AND

  17. Information Systems: Current Developments and Future Expansion.

    ERIC Educational Resources Information Center

    1970

    On May 20, 1970, a one-day seminar was held for Congressional members and staff. The papers given at this seminar and included in the proceedings are: (1) "Understanding Information Systems" by J. D. Aron, (2) "Computer Applications in Political Science" by Kenneth Janda, (3) "Who's the Master of Your Information System?" by Marvin Kornbluh, (4)…

  18. Changes in Information Systems in Czech Agriculture

    ERIC Educational Resources Information Center

    Slavik, Milan

    2004-01-01

    A study carried out in 1998 (reported in the Journal of Agricultural Education and Extension, 2003) of the information systems used by farmers in the Czech Republic to access information and advice was repeated in 2003. The research aim was to assess whether, and how, the systems had changed during these five years. The perceived importance of 10…

  19. Developing WWW Information Systems on the Internet.

    ERIC Educational Resources Information Center

    Wang, Jianqun; Reid, Edna O. F.

    1996-01-01

    Discusses basic concepts and technologies related to World Wide Web information system development. Describes the design and implementation of Virtual Travel Mart, a Web-based end- user oriented information system. Emphasizes design considerations, which focus on user needs; creativity; integration of in-house databases on the Internet; currency;…

  20. Innovations in an Accounting Information Systems Course.

    ERIC Educational Resources Information Center

    Shaoul, Jean

    A new approach to teaching an introductory accounting information systems course is outlined and the potential of this approach for integrating computers into the accounting curriculum at Manchester University (England) is demonstrated. Specifically, the use of a small inventory recording system and database in an accounting information course is…

  1. Performance Information Management System (PIMS) Communication

    DTIC Science & Technology

    1993-12-31

    34AD-A284 851 AD MIPR NO. MIPR 92MM2501 TITLE: Performance Information Management System (PIMS) Communication PRINCIPAL INVESTIGATOR: Kathryn P...93 . . ..- F •nal,. 12/1/91 - 12/31/93- ...... . ..... PIMS-Performance Information Management System Communications 92MM2501 Kathryn P. Winter Navy

  2. Developing an Undergraduate Information Systems Security Track

    ERIC Educational Resources Information Center

    Sharma, Aditya; Murphy, Marianne C.; Rosso, Mark A.; Grant, Donna

    2013-01-01

    Information Systems Security as a specialized area of study has mostly been taught at the graduate level. This paper highlights the efforts of establishing an Information Systems (IS) Security track at the undergraduate level. As there were many unanswered questions and concerns regarding the Security curriculum, focus areas, the benefit of…

  3. ENVIRONMENTAL INFORMATION MANAGEMENT SYSTEM (EIMS) FACT SHEET

    EPA Science Inventory

    The purpose of the fact sheet is to provide information about the US EPA Office of Research and Developments Environmental Information Management System. The fact sheet indicates the type of records that are in EIMS, systems that are integrated with EIMS as well as some highligh...

  4. Why information systems are helpful to nursing.

    PubMed

    Elkind, Elizabeth C

    2009-03-01

    The age of technology and the information age are now and in the future. Information systems are valuable tools to facilitate nursing care and nursing education at all levels. As the nursing profession continues to adopt technology and information systems, it will create unique opportunities for improving and impacting nursing care and outcomes using dynamic tools. Nurses need to embrace the transformation and be a role model for the healthcare delivery team and consumers.

  5. Display system for imaging scientific telemetric information

    NASA Technical Reports Server (NTRS)

    Zabiyakin, G. I.; Rykovanov, S. N.

    1979-01-01

    A system for imaging scientific telemetric information, based on the M-6000 minicomputer and the SIGD graphic display, is described. Two dimensional graphic display of telemetric information and interaction with the computer, in analysis and processing of telemetric parameters displayed on the screen is provided. The running parameter information output method is presented. User capabilities in the analysis and processing of telemetric information imaged on the display screen and the user language are discussed and illustrated.

  6. Strategies for Building Distributed Information Retrieval Systems.

    ERIC Educational Resources Information Center

    Macleod, Ian A.; And Others

    1987-01-01

    Discussion of the need for distributed information retrieval systems focuses on a model system, Fulcrum FUL/Text. Differences from distributed database management systems are described; system design is discussed; implementation requirements are explained including remote operation calls (ROC's); and a prototype simulation model based on FUL/Text…

  7. MiSIS: Michigan Student Information System.

    ERIC Educational Resources Information Center

    Michigan State Dept. of Education, Lansing. Higher Education Management Services.

    The Michigan Student Information System (MiSIS) is the student flow component, of the Michigan Community College Occupational Education Evaluation System (MCCOEES), a comprehensive state-wide system for evaluating occupational education. It was developed by the Michigan community college system as a systematic and valid method of collecting…

  8. MiSIS: Michigan Student Information System.

    ERIC Educational Resources Information Center

    Michigan State Dept. of Education, Lansing. Higher Education Management Services.

    The Michigan Student Information System (MiSIS) is the student flow component, of the Michigan Community College Occupational Education Evaluation System (MCCOEES), a comprehensive state-wide system for evaluating occupational education. It was developed by the Michigan community college system as a systematic and valid method of collecting…

  9. Integrated Information Systems: A Leading Edge Application.

    ERIC Educational Resources Information Center

    Hopkins, William L.

    1986-01-01

    Describes the Navy's Military Personnel Records System (MPRS), an updatable micrographics system that is evolving into a sophisticated and innovative optical data disk automated personnel information system for officers and enlisted personnel. Highlights include current and proposed systems, their evolution, operating characteristics, and project…

  10. Conceptual Design of a Regional Information System.

    ERIC Educational Resources Information Center

    Denver Regional Council of Governments, CO.

    This report describes the conceptual design of a regional information system, developed in support of the Denver Regional Council of Government's established comprehensive planning work program. It includes a discussion of system objectives, available data sources, recommended system content, software and system maintenance requirements,…

  11. Baltimore's Automated Information Systems Inventory. Revised.

    ERIC Educational Resources Information Center

    Durr, W. T.; And Others

    The City of Baltimore utilizes an automated information system centered on finance and personnel administration. This survey of the system as of summer 1975 describes 15 categories of operations systems serving approximately 50 purposes. Each system is described by department, bureau, and services. These include: Bureau of Management Information…

  12. Using geographic information systems in injury research.

    PubMed

    Edelman, Linda S

    2007-01-01

    To provide an overview of geographic information systems (GIS) and to discuss current and future applications in injury and trauma research. Literature review and discourse of GIS technology related to injury and trauma research. A search of scientific literature databases, text books, and online resources was undertaken to describe the current and prospective uses of GIS in injury and trauma research. Geographic information systems are computerized mapping systems that link information from different data sets spatially. The advantage of GIS is the capability to graphically display different attributes of an area in a way that is easily interpretable. Geographic information systems have been used to study injury rates, describe populations at risk for injury, examine access to trauma care, and develop and assess injury prevention programs. Geographic information systems are tools for injury researchers to analyze injury rates and risks and to describe their results with colorful maps and graphics that allow the public to see how injuries affect their communities.

  13. In-vehicle information system functions

    SciTech Connect

    Tufano, D.R.; Spelt, P.F.; Knee, H.E.

    1997-04-01

    This paper describes the functional requirement for an In-Vehicle Information System (IVIS), which will manage and display all driving-related information from many sources. There are numerous information systems currently being fielded or developed (e.g., routing and navigation, collision avoidance). However, without a logical integration of all of the possible on-board information, there is a potential for overwhelming the driver. The system described in this paper will filter and prioritize information across all sources, and present it to the driver in a timely manner, within a unified interface. To do this, IVIS will perform three general functions: (1) interact with other, on-board information subsystems and the vehicle; (2) manage the information by filtering, prioritizing, and integrating it; and (3) interact with the driver, both in terms of displaying information to the driver and allowing the driver to input requests, goals and preferences. The functional requirements described in this paper have either been derived from these three high-level functions or are directly mandated by the overriding requirements for modularity and flexibility. IVIS will have to be able to accommodate different types of information subsystems, of varying level of sophistication. The system will also have to meet the diverse needs of different types of drivers (private, commercial, transit), who may have very different levels of expertise in using information systems.

  14. LapF and Its Regulation by Fis Affect the Cell Surface Hydrophobicity of Pseudomonas putida

    PubMed Central

    Lahesaare, Andrio; Ainelo, Hanna; Teppo, Annika; Kivisaar, Maia; Heipieper, Hermann J.; Teras, Riho

    2016-01-01

    The ability of bacteria to regulate cell surface hydrophobicity is important for the adaptation to different environmental conditions. The hydrophobicity of cell surface can be determined by several factors, including outer membrane and surface proteins. In this study, we report that an adhesin LapF influences cell surface hydrophobicity of Pseudomonas putida. Cells lacking LapF are less hydrophobic than wild-type cells in stationary growth phase. Moreover, the overexpression of the global regulator Fis decreases surface hydrophobicity by repressing the expression of lapF. Flow cytometry analysis revealed that bacteria producing LapF are more viable when confronted with methanol (a hydrophilic compound) but are more susceptible to 1-octanol (a hydrophobic compound). Thus, these results revealed that LapF is the hydrophobicity factor for the cell surface of P. putida. PMID:27812186

  15. Infrastructuring Multicultural Healthcare Information Systems.

    PubMed

    Dreessen, Katrien; Huybrechts, Liesbeth; Grönvall, Erik; Hendriks, Niels

    2017-01-01

    This paper stresses the need for more research in the field of Participatory Design (PD) and in particular into how to design Health Information Technology (HIT) together with care providers and -receivers in multicultural settings. We contribute to this research by describing a case study, the 'Health-Cultures' project, in which we designed HIT for the context of home care of older people with a migration background. The Health-Cultures project is located in the city of Genk, Belgium, which is known for its multicultural population, formed by three historical migration waves of people coming to work in the nowadays closed coal mines. Via a PD approach, we studied existing means of dialogue and designed HIT that both care receivers and care providers in Genk can use in their daily exchanges between cultures in home care contexts. In discussing relevant literature as well as the results of this study, we point to the need and the ways of taking spatio-historical aspects of a specific healthcare situation into account in the PD of HIT to support multicultural perspectives on healthcare.

  16. Increased Maternal Genome Dosage Bypasses the Requirement of the FIS Polycomb Repressive Complex 2 in Arabidopsis Seed Development

    PubMed Central

    Kradolfer, David; Hennig, Lars; Köhler, Claudia

    2013-01-01

    Seed development in flowering plants is initiated after a double fertilization event with two sperm cells fertilizing two female gametes, the egg cell and the central cell, leading to the formation of embryo and endosperm, respectively. In most species the endosperm is a polyploid tissue inheriting two maternal genomes and one paternal genome. As a consequence of this particular genomic configuration the endosperm is a dosage sensitive tissue, and changes in the ratio of maternal to paternal contributions strongly impact on endosperm development. The FERTILIZATION INDEPENDENT SEED (FIS) Polycomb Repressive Complex 2 (PRC2) is essential for endosperm development; however, the underlying forces that led to the evolution of the FIS-PRC2 remained unknown. Here, we show that the functional requirement of the FIS-PRC2 can be bypassed by increasing the ratio of maternal to paternal genomes in the endosperm, suggesting that the main functional requirement of the FIS-PRC2 is to balance parental genome contributions and to reduce genetic conflict. We furthermore reveal that the AGAMOUS LIKE (AGL) gene AGL62 acts as a dosage-sensitive seed size regulator and that reduced expression of AGL62 might be responsible for reduced size of seeds with increased maternal genome dosage. PMID:23326241

  17. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction.

    PubMed

    Iwasawa, Ryota; Mahul-Mellier, Anne-Laure; Datler, Christoph; Pazarentzos, Evangelos; Grimm, Stefan

    2011-02-02

    The mitochondria and the endoplasmic reticulum (ER) are two organelles that critically contribute to apoptosis induction. While it is established that they communicate, how cell death signals are transmitted from the mitochondria to the ER is unknown. Here, we show that the mitochondrial fission protein Fission 1 homologue (Fis1) conveys an apoptosis signal from the mitochondria to the ER by interacting with Bap31 at the ER and facilitating its cleavage into the pro-apoptotic p20Bap31. Exogenous apoptosis inducers likewise use this signalling route and induce the procession of Bap31. Moreover, we show that the recruitment of procaspase-8 to the Fis1-Bap31 platform is an early event during apoptosis induction. The association of procaspase-8 with the Fis1-Bap31 complex is dependent on the variant of death effector domain (vDED) in Bap31 and is required for the activation of procaspase-8. This signalling pathway establishes a feedback loop by releasing Ca(2+) from the ER that activates the mitochondria for apoptosis. Hence, the Fis1-Bap31 complex (ARCosome) that spans the mitochondria-ER interface serves as a platform to activate the initiator procaspase-8, and thereby bridges two critical organelles for apoptosis signalling.

  18. Sensorpedia: Information Sharing Across Autonomous Sensor Systems

    SciTech Connect

    Gorman, Bryan L; Resseguie, David R; Tomkins-Tinch, Christopher H

    2009-01-01

    The concept of adapting social media technologies is introduced as a means of achieving information sharing across autonomous sensor systems. Historical examples of interoperability as an underlying principle in loosely-coupled systems is compared and contrasted with corresponding tightly-coupled, integrated systems. Examples of ad hoc information sharing solutions based on Web 2.0 social networks, mashups, blogs, wikis, and data tags are presented and discussed. The underlying technologies of these solutions are isolated and defined, and Sensorpedia is presented as a formalized application for implementing sensor information sharing across large-scale enterprises with incompatible autonomous sensor systems.

  19. The Oklahoma Geographic Information Retrieval System

    NASA Technical Reports Server (NTRS)

    Blanchard, W. A.

    1982-01-01

    The Oklahoma Geographic Information Retrieval System (OGIRS) is a highly interactive data entry, storage, manipulation, and display software system for use with geographically referenced data. Although originally developed for a project concerned with coal strip mine reclamation, OGIRS is capable of handling any geographically referenced data for a variety of natural resource management applications. A special effort has been made to integrate remotely sensed data into the information system. The timeliness and synoptic coverage of satellite data are particularly useful attributes for inclusion into the geographic information system.

  20. The Air Program Information Management System (APIMS)

    DTIC Science & Technology

    2011-11-02

    Technology November 2, 2011 The Air Program Information Management System (APIMS) Frank Castaneda, III, P.E. APIMS Program Manager AFCEE/TDNQ APIMS...NOV 2011 2. REPORT TYPE 3. DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE The Air Program Information Management System (APIMS... Information   Management   System : Sustainability of  Enterprise air quality management system • Aspects and Impacts to Process • Auditing and Measurement

  1. BIO-Plex Information System Concept

    NASA Technical Reports Server (NTRS)

    Jones, Harry; Boulanger, Richard; Arnold, James O. (Technical Monitor)

    1999-01-01

    This paper describes a suggested design for an integrated information system for the proposed BIO-Plex (Bioregenerative Planetary Life Support Systems Test Complex) at Johnson Space Center (JSC), including distributed control systems, central control, networks, database servers, personal computers and workstations, applications software, and external communications. The system will have an open commercial computing and networking, architecture. The network will provide automatic real-time transfer of information to database server computers which perform data collection and validation. This information system will support integrated, data sharing applications for everything, from system alarms to management summaries. Most existing complex process control systems have information gaps between the different real time subsystems, between these subsystems and central controller, between the central controller and system level planning and analysis application software, and between the system level applications and management overview reporting. An integrated information system is vitally necessary as the basis for the integration of planning, scheduling, modeling, monitoring, and control, which will allow improved monitoring and control based on timely, accurate and complete data. Data describing the system configuration and the real time processes can be collected, checked and reconciled, analyzed and stored in database servers that can be accessed by all applications. The required technology is available. The only opportunity to design a distributed, nonredundant, integrated system is before it is built. Retrofit is extremely difficult and costly.

  2. Interactive information retrieval systems with minimalist representation

    SciTech Connect

    Domeshek, E.; Kedar, S.; Gordon, A.

    1996-12-31

    Almost any information you might want is becoming available on-line. The problem is how to find what you need. One strategy to improve access to existing information sources, is intelligent information agents - an approach based on extensive representation and inference. Another alternative is to simply concentrate on better information organization and indexing. Our systems use a form of conceptual indexing sensitive to users` task-specific information needs. We aim for minimalist representation, coding only select aspects of stored items. Rather than supporting reliable automated inference, the primary purpose of our representations is to provide sufficient discrimination and guidance to a user for a given domain and task. This paper argues, using case studies, that minimal representations can make strong contributions to the usefulness and usability of interactive information systems, while minimizing knowledge engineering effort. We demonstrate this approach in several broad spectrum applications including video retrieval and advisory systems.

  3. Personal medical information system using laser card

    NASA Astrophysics Data System (ADS)

    Cho, Seong H.; Kim, Keun Ho; Choi, Hyung-Sik; Park, Hyun Wook

    1996-04-01

    The well-known hospital information system (HIS) and the picture archiving and communication system (PACS) are typical applications of multimedia to medical area. This paper proposes a personal medical information save-and-carry system using a laser card. This laser card is very useful, especially in emergency situations, because the medical information in the laser card can be read at anytime and anywhere if there exists a laser card reader/writer. The contents of the laser card include the clinical histories of a patient such as clinical chart, exam result, diagnostic reports, images, and so on. The purpose of this system is not a primary diagnosis, but emergency reference of clinical history of the patient. This personal medical information system consists of a personal computer integrated with laser card reader/writer, color frame grabber, color CCD camera and a high resolution image scanner optionally. Window-based graphical user interface was designed for easy use. The laser card has relatively sufficient capacity to store the personal medical information, and has fast access speed to restore and load the data with a portable size as compact as a credit card. Database items of laser card provide the doctors with medical data such as laser card information, patient information, clinical information, and diagnostic result information.

  4. Biomass energy systems information user study

    SciTech Connect

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1981-02-01

    The results of a series of telephone interviews with groups of users of information on biomass energy systems are described. These results, part of a larger study on many different solar technologies, identify types of information each group needed and the best ways to get information to each group. This report is 1 of 10 discussing study results. The overall study provides baseline data about information needs in the solar community. Results from 12 biomass groups of respondents are analyzed in this report: Federally Funded Researchers (2 groups), Nonfederally Funded Researchers (2 groups), Representatives of Manufacturers (2 groups), Representatives of State Forestry Offices, Private Foresters, Forest Products Engineers, Educators, Cooperative Extension Service County Agents, and System Managers. The data will be used as input to the determination of information products and services the Solar Energy Research Institute, the Solar Energy Information Data Bank Network, and the entire information outreach community should be preparing and disseminating.

  5. Implementation and operational experience of an integrated fuel information service at the BNFL THORP facility

    SciTech Connect

    Robson, D.N.; Ramsden, P.N.

    1995-12-31

    An integrated data management service for the fuel storage areas of British Nuclear Fuel Limited`s (BNFL`s) Thermal Oxide Reprocessing Plant (THORP) Division has been implemented to replace several independent systems. This fuel information service (FIS) has brought the nuclear materials accountancy and safeguards records together with the operating records into one database from which all safeguards reports are made. The BNFL`s contractual and commercial and technical data on the stored fuel, required to plan reprocessing campaigns, has also been brought into the common database. A commercially available software package, widely used in warehousing applications and the food and drugs industries, has been used as the basis of FIS. System enhancements and customization have been developed in partnership between THORP Division, BNFL IT Services, and the software supplier. The FIS is the first stage in a project to integrate the materials management systems throughout the THORP nuclear recycling business, including irradiated fuel receipt and storage, reprocessing and storage of products, mixed-oxide fuel manufacture, and the conditioning and storage of wastes.

  6. University Program Management Information System

    NASA Technical Reports Server (NTRS)

    Gans, Gary (Technical Monitor)

    2002-01-01

    As basic policy, NASA believes that colleges and universities should be encouraged to participate in the nation's space and aeronautics program to the maximum extent practicable. Indeed, universities are considered as partners with government and industry in the nation's aerospace program. NASA's objective is to have them bring their scientific, engineering, and social research competence to bear on aerospace problems and on the broader social, economic, and international implications of NASA's technical and scientific programs. It is expected that, in so doing, universities will strengthen both their research and their educational capabilities to contribute more effectively to the national well-being. This annual report is one means of documenting the NASA-university relationship, frequently denoted, collectively, as NASA's University Program. This report is consistent with agency accounting records, as the data is obtained from NASA's Financial and Contractual Status (FACS) System, operated by the Financial Management Division and the Procurement Office. However, in accordance with interagency agreements, the orientation differs from that required for financial or procurement purposes. Any apparent discrepancies between this report and other NASA procurement or financial reports stem from the selection criteria for the data. This report was prepared by the Education Division/FE, Office of Human Resources and Education.

  7. University Program Management Information System

    NASA Technical Reports Server (NTRS)

    Gans, Gary (Technical Monitor)

    2004-01-01

    As basic policy, NASA believes that colleges and universities should be encouraged to participate in the nation's space and aeronautics program to the maximum extent practicable. Indeed, universities are considered as partners with government and industry in the nation's aerospace program. NASA's objective is to have them bring their scientific, engineering, and social research competence to bear on aerospace problems and on the broader social, economic, and international implications of NASA's technical and scientific programs. It is expected that, in so doing, universities will strengthen both their research and their educational capabilities to contribute more effectively to the national well being. This annual report is one means of documenting the NASA-university relationship, frequently denoted, collectively, as NASA's University Program. This report is consistent with agency accounting records, as the data is obtained from NASA's Financial and Contractual Status (FACS) System, operated by the Financial Management Division and the Procurement Office. However, in accordance with interagency agreements, the orientation differs from that required for financial or procurement purposes. Any apparent discrepancies between this report and other NASA procurement or financial reports stem from the selection criteria for the data.

  8. University Program Management Information System

    NASA Technical Reports Server (NTRS)

    2001-01-01

    As basic policy, NASA believes that colleges and universities should be encouraged to participate in the nation's space and aeronautics program to the maximum extent practicable. Indeed, universities are considered as partners with government and industry in the nation's aerospace program. NASA' objective is to have them bring their scientific, engineering, and social research competence to bear on aerospace problems and on the broader social, economic, and international implications of NASA's technical and scientific programs. It is expected that, in so doing, universities will strengthen both their research and their educational capabilities to contribute more effectively to the national well being. This annual report is one means of documenting the NASA-university relationship, frequently denoted, collectively, as NASA's University Program. This report is consistent with agency accounting records, as the data is obtained from NASA's Financial and Contractual Status (FACS) System, operated by the Financial Management Division and the Procurement Office. However, in accordance with interagency agreements, the orientation differs from that required for financial or procurement purposes. Any apparent discrepancies between this report and other NASA procurement or financial reports stem from the selection criteria for the data.

  9. Decentralized Multisensory Information Integration in Neural Systems

    PubMed Central

    Zhang, Wen-hao; Chen, Aihua

    2016-01-01

    How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. SIGNIFICANCE STATEMENT To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that

  10. River Protection Project information systems assessment

    SciTech Connect

    JOHNSON, A.L.

    1999-07-28

    The Information Systems Assessment Report documents the results from assessing the Project Hanford Management Contract (PHMC) Hanford Data Integrator 2000 (HANDI 2000) system, Business Management System (BMS) and Work Management System phases (WMS), with respect to the System Engineering Capability Assessment Model (CAM). The assessment was performed in accordance with the expectations stated in the fiscal year (FY) 1999 Performance Agreement 7.1.1, item (2) which reads, ''Provide an assessment report on the selected Integrated Information System by July 31, 1999.'' This report assesses the BMS and WMS as implemented and planned for the River Protection Project (RPP). The systems implementation is being performed under the PHMC HANDI 2000 information system project. The project began in FY 1998 with the BMS, proceeded in FY 1999 with the Master Equipment List portion of the WMS, and will continue the WMS implementation as funding provides. This report constitutes an interim quality assessment providing information necessary for planning RPP's information systems activities. To avoid confusion, HANDI 2000 will be used when referring to the entire system, encompassing both the BMS and WMS. A graphical depiction of the system is shown in Figure 2-1 of this report.

  11. The usability axiom of medical information systems.

    PubMed

    Pantazi, Stefan V; Kushniruk, Andre; Moehr, Jochen R

    2006-12-01

    In this article we begin by connecting the concept of simplicity of user interfaces of information systems with that of usability, and the concept of complexity of the problem-solving in information systems with the concept of usefulness. We continue by stating "the usability axiom" of medical information technology: information systems must be, at the same time, usable and useful. We then try to show why, given existing technology, the axiom is a paradox and we continue with analysing and reformulating it several times, from more fundamental information processing perspectives. We underline the importance of the concept of representation and demonstrate the need for context-dependent representations. By means of thought experiments and examples, we advocate the need for context-dependent information processing and argue for the relevance of algorithmic information theory and case-based reasoning in this context. Further, we introduce the notion of concept spaces and offer a pragmatic perspective on context-dependent representations. We conclude that the efficient management of concept spaces may help with the solution to the medical information technology paradox. Finally, we propose a view of informatics centred on the concepts of context-dependent information processing and management of concept spaces that aligns well with existing knowledge centric definitions of informatics in general and medical informatics in particular. In effect, our view extends M. Musen's proposal and proposes a definition of Medical Informatics as context-dependent medical information processing. The axiom that medical information systems must be, at the same time, useful and usable, is a paradox and its investigation by means of examples and thought experiments leads to the recognition of the crucial importance of context-dependent information processing. On the premise that context-dependent information processing equates to knowledge processing, this view defines Medical Informatics

  12. Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli

    PubMed Central

    Kahramanoglou, Christina; Seshasayee, Aswin S. N.; Prieto, Ana I.; Ibberson, David; Schmidt, Sabine; Zimmermann, Jurgen; Benes, Vladimir; Fraser, Gillian M.

    2011-01-01

    Nucleoid-associated proteins (NAPs) are global regulators of gene expression in Escherichia coli, which affect DNA conformation by bending, wrapping and bridging the DNA. Two of these—H-NS and Fis—bind to specific DNA sequences and structures. Because of their importance to global gene expression, the binding of these NAPs to the DNA was previously investigated on a genome-wide scale using ChIP-chip. However, variation in their binding profiles across the growth phase and the genome-scale nature of their impact on gene expression remain poorly understood. Here, we present a genome-scale investigation of H-NS and Fis binding to the E. coli chromosome using chromatin immunoprecipitation combined with high-throughput sequencing (ChIP-seq). By performing our experiments under multiple time-points during growth in rich media, we show that the binding regions of the two proteins are mutually exclusive under our experimental conditions. H-NS binds to significantly longer tracts of DNA than Fis, consistent with the linear spread of H-NS binding from high- to surrounding lower-affinity sites; the length of binding regions is associated with the degree of transcriptional repression imposed by H-NS. For Fis, a majority of binding events do not lead to differential expression of the proximal gene; however, it has a significant indirect effect on gene expression partly through its effects on the expression of other transcription factors. We propose that direct transcriptional regulation by Fis is associated with the interaction of tandem arrays of Fis molecules to the DNA and possible DNA bending, particularly at operon-upstream regions. Our study serves as a proof-of-principle for the use of ChIP-seq for global DNA-binding proteins in bacteria, which should become significantly more economical and feasible with the development of multiplexing techniques. PMID:21097887

  13. Welcome to health information science and systems.

    PubMed

    Zhang, Yanchun

    2013-01-01

    Health Information Science and Systems is an exciting, new, multidisciplinary journal that aims to use technologies in computer science to assist in disease diagnoses, treatment, prediction and monitoring through the modeling, design, development, visualization, integration and management of health related information. These computer-science technologies include such as information systems, web technologies, data mining, image processing, user interaction and interface, sensors and wireless networking and are applicable to a wide range of health related information including medical data, biomedical data, bioinformatics data, public health data.

  14. Autonomous Organization-Based Adaptive Information Systems

    DTIC Science & Technology

    2005-01-01

    intentional Multi - agent System (MAS) approach [10]. While these approaches are functional AIS systems, they lack the ability to reorganize and adapt...extended a multi - agent system with a self- reorganizing architecture to create an autonomous, adaptive information system. Design Our organization-based...goals. An advantage of a multi - agent system using the organization theoretic model is its extensibility. The practical, numerical limits to the

  15. The NASTRAN Error Correction Information System (ECIS)

    NASA Technical Reports Server (NTRS)

    Rosser, D. C., Jr.; Rogers, J. L., Jr.

    1975-01-01

    A data management procedure, called Error Correction Information System (ECIS), is described. The purpose of this system is to implement the rapid transmittal of error information between the NASTRAN Systems Management Office (NSMO) and the NASTRAN user community. The features of ECIS and its operational status are summarized. The mode of operation for ECIS is compared to the previous error correction procedures. It is shown how the user community can have access to error information much more rapidly when using ECIS. Flow charts and time tables characterize the convenience and time saving features of ECIS.

  16. Comprehensive Child Welfare Information System. Final rule.

    PubMed

    2016-06-02

    This final rule replaces the Statewide and Tribal Automated Child Welfare Information Systems (S/TACWIS) rule with the Comprehensive Child Welfare Information System (CCWIS) rule. The rule also makes conforming amendments in rules in related requirements. This rule will assist title IV-E agencies in developing information management systems that leverage new innovations and technology in order to better serve children and families. More specifically, this final rule supports the use of cost-effective, innovative technologies to automate the collection of high-quality case management data and to promote its analysis, distribution, and use by workers, supervisors, administrators, researchers, and policy makers.

  17. Graphic Information Presentation System (GIPSY) Users Manual

    DTIC Science & Technology

    1991-02-01

    AD-A238 830 (1 *USERS MANUAL UM 7-91 1 FEBRUARY 1991 m 4 JOINT DA TA SYSTEMS SUPPORT CENTER • USERS MANUAL FOR THE GRAPHIC INFORMATION PRESENTATION...Users Manual, UM 7-91 1. This is change 1 to JDSSC Users Manual UM 7-91 titled Graphic Information Presentation System (GIPSY) Users Manual (UM 7-91...THOMAS R. E SON Deputy Director, NMCS ADP S JOINT DATA SYSTEMS SUPPORT CENTER Users Manual UM 7-91 1 February 1991 USERS MANUAL FOR THE GRAPHIC INFORMATION

  18. Multipurpose Interactive NASA Information Systems (MINIS)

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The Multipurpose Interactive NASA Information System was developed to provide remote, interactive information retrieval capability for various types of data bases to be processed on different types of small and medium size computers. Use of the system for three different data bases is decribed: (1) LANDSAT photo look-up, (2) land use, and (3) census/socioeconomic. Each of the data base elements is shown together with other detailed information that a user would require to contact the system remotely, to transmit inquiries on commands, and to receive the results of the queries or commands.

  19. Corporate information systems in health organisations.

    PubMed

    Smith, J

    1997-01-01

    This paper presents an overview of the nature of corporate information systems and their applications in health organisations. It emphasises the importance of financial and human resource information in the creation of a corporate data model. The paper summarises the main features of finance and human resource systems as they are used in health organisations. It looks at a series of case studies carried out in health organisations, which were selected on the basis of their representation of different aspects of service delivery. It also discusses the theoretical and practical perspectives of the systems themselves, their roles in information management, executive and decision support, and in planning and forecasting.

  20. Requirements Analysis for Information-Intensive Systems

    NASA Technical Reports Server (NTRS)

    Callender, E. D.; Hartsough, C.; Morris, R. V.; Yamamoto, Y.

    1986-01-01

    Report discusses role of requirements analysis in development of information-intensive systems. System examined from variety of human viewpoints during design, development, and implementation. Such examination, called requirements analysis, ensures system simultaneously meets number of distinct but interacting needs. Viewpoints defined and integrated to help attain objectives.

  1. Plans for a National Physics Information System.

    ERIC Educational Resources Information Center

    Alt, Franz L.; Herschman, Arthur

    Against a background of widespread interest in national information systems, the American Institute of Physics is developing such a system for physics. This program pivots on the design of a new classification system for physics which is to be used, in conjunction with free-language index terms, for the intellectual organization of the physics…

  2. GUIDE-0: An Experimental Information System.

    ERIC Educational Resources Information Center

    Murai, Shinnichi

    A description is provided of GUIDE-0, an experimental information system. The system serves as a bibliographic aid for students who are taking introductory computer science courses whose material is at least partially implemented via PLATO-IV lessons. Following a brief introduction to the system in Chapter I, the second Chapter describes the…

  3. Applying Management Information Systems to Staffing.

    ERIC Educational Resources Information Center

    Hanson, Robert L.

    1982-01-01

    After reviewing some concepts and principles for effective data management, the author applies the concepts to nurse staffing systems for the management of human resources. He defines a seven-step process for establishing a management information system, from defining the management objective to implementing the system. (Author/CT)

  4. Syllabus Information Depiction System (SIDS) user's guide

    SciTech Connect

    Waterman, D.K.; Skinner, N.L.

    1987-10-01

    The Syllabus Information Depiction System (SIDS) is an automated tool designed to track the aircrew training syllabi of the Marine Corps. This report is the User's Manual for this data base system, providing users with instructions to help them use the system more efficiently. This document contains printed screen layouts that will guide the user step-by-step through the written instructions.

  5. Effective Information Systems: What's the Secret?

    ERIC Educational Resources Information Center

    Kirkham, Sandi

    1994-01-01

    Argues that false assumptions about user needs implicit in methodologies for building information systems have resulted in inadequate and inflexible systems. Checkland's Soft Systems Methodology is examined as a useful alternative. Its fundamental features are described, and examples of models demonstrate how the methodology can facilitate…

  6. The Changing Environment of Management Information Systems.

    ERIC Educational Resources Information Center

    Tagawa, Ken

    1982-01-01

    The promise of mainframe computers in the 1970s for management information systems (MIS) is largely unfulfilled, and newer office automation systems and data communication systems are designed to be responsive to MIS needs. The status of these innovations is briefly outlined. (MSE)

  7. Plans for a National Physics Information System.

    ERIC Educational Resources Information Center

    Alt, Franz L.; Herschman, Arthur

    Against a background of widespread interest in national information systems, the American Institute of Physics is developing such a system for physics. This program pivots on the design of a new classification system for physics which is to be used, in conjunction with free-language index terms, for the intellectual organization of the physics…

  8. Docu/Master Information Retrieval System.

    ERIC Educational Resources Information Center

    Poor, William E.

    1987-01-01

    Describes an information storage and retrieval system for mainframe computer applications and its utilization as a corporate library catalog intended for end-user searching. The changeover from a previous system is discussed and current system features are evaluated. (Author/CLB)

  9. Information processing capacity of dynamical systems.

    PubMed

    Dambre, Joni; Verstraeten, David; Schrauwen, Benjamin; Massar, Serge

    2012-01-01

    Many dynamical systems, both natural and artificial, are stimulated by time dependent external signals, somehow processing the information contained therein. We demonstrate how to quantify the different modes in which information can be processed by such systems and combine them to define the computational capacity of a dynamical system. This is bounded by the number of linearly independent state variables of the dynamical system, equaling it if the system obeys the fading memory condition. It can be interpreted as the total number of linearly independent functions of its stimuli the system can compute. Our theory combines concepts from machine learning (reservoir computing), system modeling, stochastic processes, and functional analysis. We illustrate our theory by numerical simulations for the logistic map, a recurrent neural network, and a two-dimensional reaction diffusion system, uncovering universal trade-offs between the non-linearity of the computation and the system's short-term memory.

  10. Information Processing Capacity of Dynamical Systems

    PubMed Central

    Dambre, Joni; Verstraeten, David; Schrauwen, Benjamin; Massar, Serge

    2012-01-01

    Many dynamical systems, both natural and artificial, are stimulated by time dependent external signals, somehow processing the information contained therein. We demonstrate how to quantify the different modes in which information can be processed by such systems and combine them to define the computational capacity of a dynamical system. This is bounded by the number of linearly independent state variables of the dynamical system, equaling it if the system obeys the fading memory condition. It can be interpreted as the total number of linearly independent functions of its stimuli the system can compute. Our theory combines concepts from machine learning (reservoir computing), system modeling, stochastic processes, and functional analysis. We illustrate our theory by numerical simulations for the logistic map, a recurrent neural network, and a two-dimensional reaction diffusion system, uncovering universal trade-offs between the non-linearity of the computation and the system's short-term memory. PMID:22816038

  11. Clinical Information Systems - From Yesterday to Tomorrow.

    PubMed

    Gardner, R M

    2016-06-30

    To review the history of clinical information systems over the past twenty-five years and project anticipated changes to those systems over the next twenty-five years. Over 250 Medline references about clinical information systems, quality of patient care, and patient safety were reviewed. Books, Web resources, and the author's personal experience with developing the HELP system were also used. There have been dramatic improvements in the use and acceptance of clinical computing systems and Electronic Health Records (EHRs), especially in the United States. Although there are still challenges with the implementation of such systems, the rate of progress has been remarkable. Over the next twenty-five years, there will remain many important opportunities and challenges. These opportunities include understanding complex clinical computing issues that must be studied, understood and optimized. Dramatic improvements in quality of care and patient safety must be anticipated as a result of the use of clinical information systems. These improvements will result from a closer involvement of clinical informaticians in the optimization of patient care processes. Clinical information systems and computerized clinical decision support have made contributions to medicine in the past. Therefore, by using better medical knowledge, optimized clinical information systems, and computerized clinical decision, we will enable dramatic improvements in both the quality and safety of patient care in the next twenty-five years.

  12. Guest editorial. Integrated healthcare information systems.

    PubMed

    Li, Ling; Ge, Ri-Li; Zhou, Shang-Ming; Valerdi, Ricardo

    2012-07-01

    The use of integrated information systems for healthcare has been started more than a decade ago. In recent years, rapid advances in information integration methods have spurred tremendous growth in the use of integrated information systems in healthcare delivery. Various techniques have been used for probing such integrated systems. These techniques include service-oriented architecture (SOA), EAI, workflow management, grid computing, and others. Many applications require a combination of these techniques, which gives rise to the emergence of enterprise systems in healthcare. Development of the techniques originated from different disciplines has the potential to significantly improve the performance of enterprise systems in healthcare. This editorial paper briefly introduces the enterprise systems in the perspective of healthcare informatics.

  13. Data vs. information: A system paradigm

    NASA Technical Reports Server (NTRS)

    Billingsley, F. C.

    1982-01-01

    The data system designer requires data parameters, and is dependent on the user to convert information needs to these data parameters. This conversion will be done with more or less accuracy, beginning a chain of inaccuracies which propagate through the system, and which, in the end, may prevent the user from converting the data received into the information required. The concept to be pursued is that errors occur in various parts of the system, and, having occurred, propagate to the end. Modeling of the system may allow an estimation of the effects at any point and the final accumulated effect, and may prove a method of allocating an error budget among the system components. The selection of the various technical parameters which a data system must meet must be done in relation to the ability of the user to turn the cold, impersonal data into a live, personal decision or piece of information.

  14. Development of living body information monitoring system

    NASA Astrophysics Data System (ADS)

    Sakamoto, Hidetoshi; Ohbuchi, Yoshifumi; Torigoe, Ippei; Miyagawa, Hidekazu; Murayama, Nobuki; Hayashida, Yuki; Igasaki, Tomohiko

    2010-03-01

    The easy monitoring systems of contact and non-contact living body information for preventing the the Sudden Infant Death Syndrome (SIDS) were proposed as an alternative monitoring system of the infant's vital information. As for the contact monitoring system, respiration sensor, ECG electrodes, thermistor and IC signal processor were integrated into babies' nappy holder. This contact-monitoring unit has RF transmission function and the obtained data are analyzed in real time by PC. In non-contact mortaring system, the infrared thermo camera was used. The surrounding of the infant's mouth and nose is monitored and the respiration rate is obtained by thermal image processing of its temperature change image of expired air. This proposed system of in-sleep infant's vital information monitoring system and unit are very effective as not only infant's condition monitoring but also nursing person's one.

  15. Development of living body information monitoring system

    NASA Astrophysics Data System (ADS)

    Sakamoto, Hidetoshi; Ohbuchi, Yoshifumi; Torigoe, Ippei; Miyagawa, Hidekazu; Murayama, Nobuki; Hayashida, Yuki; Igasaki, Tomohiko

    2009-12-01

    The easy monitoring systems of contact and non-contact living body information for preventing the the Sudden Infant Death Syndrome (SIDS) were proposed as an alternative monitoring system of the infant's vital information. As for the contact monitoring system, respiration sensor, ECG electrodes, thermistor and IC signal processor were integrated into babies' nappy holder. This contact-monitoring unit has RF transmission function and the obtained data are analyzed in real time by PC. In non-contact mortaring system, the infrared thermo camera was used. The surrounding of the infant's mouth and nose is monitored and the respiration rate is obtained by thermal image processing of its temperature change image of expired air. This proposed system of in-sleep infant's vital information monitoring system and unit are very effective as not only infant's condition monitoring but also nursing person's one.

  16. The renewable electric plant information system

    SciTech Connect

    Sinclair, K.

    1995-12-01

    This report explains the procedures used for creating the Renewable Electric Plant Information System (REPiS) database, describes the database fields, and summarizes the data. The REPiS database contains comprehensive information on grid-connected renewable electric generation plants in the United States. Originally designed in 1987 and updated in 1990, the database includes information through 1994. The report also illustrates ways of using the data for analysis is and describes how researchers validated the data.

  17. Recording information on protein complexes in an information management system.

    PubMed

    Savitsky, Marc; Diprose, Jonathan M; Morris, Chris; Griffiths, Susanne L; Daniel, Edward; Lin, Bill; Daenke, Susan; Bishop, Benjamin; Siebold, Christian; Wilson, Keith S; Blake, Richard; Stuart, David I; Esnouf, Robert M

    2011-08-01

    The Protein Information Management System (PiMS) is a laboratory information management system (LIMS) designed for use with the production of proteins in a research environment. The software is distributed under the CCP4 licence, and so is available free of charge to academic laboratories. Like most LIMS, the underlying PiMS data model originally had no support for protein-protein complexes. To support the SPINE2-Complexes project the developers have extended PiMS to meet these requirements. The modifications to PiMS, described here, include data model changes, additional protocols, some user interface changes and functionality to detect when an experiment may have formed a complex. Example data are shown for the production of a crystal of a protein complex. Integration with SPINE2-Complexes Target Tracker application is also described.

  18. Recording information on protein complexes in an information management system

    PubMed Central

    Savitsky, Marc; Diprose, Jonathan M.; Morris, Chris; Griffiths, Susanne L.; Daniel, Edward; Lin, Bill; Daenke, Susan; Bishop, Benjamin; Siebold, Christian; Wilson, Keith S.; Blake, Richard; Stuart, David I.; Esnouf, Robert M.

    2011-01-01

    The Protein Information Management System (PiMS) is a laboratory information management system (LIMS) designed for use with the production of proteins in a research environment. The software is distributed under the CCP4 licence, and so is available free of charge to academic laboratories. Like most LIMS, the underlying PiMS data model originally had no support for protein–protein complexes. To support the SPINE2-Complexes project the developers have extended PiMS to meet these requirements. The modifications to PiMS, described here, include data model changes, additional protocols, some user interface changes and functionality to detect when an experiment may have formed a complex. Example data are shown for the production of a crystal of a protein complex. Integration with SPINE2-Complexes Target Tracker application is also described. PMID:21605682

  19. Computerized Information Storage and Retrieval Systems.

    ERIC Educational Resources Information Center

    Azubuike, Abraham A.; Umoh, Jackson S.

    1988-01-01

    Describes the concept of maximum indexing, a system aimed at achieving maximum recall and maximum precision in computerized information retrieval. The indexing strategies used to achieve maximum indexing and the problems that arise are discussed. (9 references) (CLB)

  20. Spinal Cord Injury Model System Information Network

    MedlinePlus

    ... for Women with SCI Video Series EatRight® Weight Management Program Smoking's Effects on ... of Alabama at Birmingham Spinal Cord Injury Model System (UAB-SCIMS) maintains this Information Network as a ...

  1. IDEAL: A methology for developing information systems

    NASA Technical Reports Server (NTRS)

    Evers, Ken H.; Bachert, Robert F.

    1988-01-01

    As a result of improved capabilities obtained through current computer technologies, application programs and expert systems, Enterprises are being designed or upgraded to be highly integrated and automated information systems. To design or modify Enterprises, it is necessary to first define what functions are to be performed within the Enterprise, identify which functions are potential candidates for automation, and what automated or expert systems are available, or must be developed, to accomplish the selected function. Second, it is necessary to define and analyze the informational requirements for each function along with the informational relationships among the functions so that a database structure can be established to support the Enterprise. To perform this type of system design, an integrated set of analysis tools is required to support the information analysis process. The IDEAL (Integrated Design and Engineering Analysis Languages) methodology provides this integrated set of tools and is discussed.

  2. Management Information Systems and the Transnational Enterprise.

    ERIC Educational Resources Information Center

    Cardozo, Max Lopes

    1978-01-01

    An analysis is made of the relationship between computers, management and trans-national corporations, followed by an examination of the influence of information systems on organization and how they function. (Author/BB)

  3. DESIGN INFORMATION ON FINE PORE AERATION SYSTEMS

    EPA Science Inventory

    Field studies were conducted over several years at municipal wastewater treatment plants employing line pore diffused aeration systems. These studies were designed to produce reliable information on the performance and operational requirements of fine pore devices under process ...

  4. Allocation of Resources in an Information System

    ERIC Educational Resources Information Center

    Bookstein, Abraham

    1974-01-01

    Considers the problem of allocation resources among various locations in an information system where phases of a process are carried out. Approach taken combines queueing theory and dynamic programming. (JB)

  5. On the Move: Mobile Information Systems.

    ERIC Educational Resources Information Center

    Hjelm, Johan

    This paper summarizes the experiences acquired during the European research project, "On the Move," and draws on some conclusions on how mobility will impact information service providers. The paper begins with a definition of mobile information systems and explains the On the Move project; the goal of On the Move is to develop a…

  6. Computerized management information systems and organizational structures

    NASA Technical Reports Server (NTRS)

    Zannetos, Z. S.; Sertel, M. R.

    1970-01-01

    The computerized management of information systems and organizational structures is discussed. The subjects presented are: (1) critical factors favoring centralization and decentralization of organizations, (2) classification of organizations by relative structure, (3) attempts to measure change in organization structure, and (4) impact of information technology developments on organizational structure changes.

  7. Michigan Occupational Information System. Administrator's Handbook.

    ERIC Educational Resources Information Center

    Michigan State Dept. of Education, Lansing. Michigan Occupational Information System.

    This handbook is designed to give introductory and reference information about the Michigan Occupational Information System (MOIS). Although focused in Michigan, it is not specifically oriented to any particular population; rather, it answers basic questions common to administrators, school principals, Michigan Employment Security Directors,…

  8. Distributing Executive Information Systems through Networks.

    ERIC Educational Resources Information Center

    Penrod, James I.; And Others

    1993-01-01

    Many colleges and universities will soon adopt distributed systems for executive information and decision support. Distribution of shared information through computer networks will improve decision-making processes dramatically on campuses. Critical success factors include administrative support, favorable organizational climate, ease of use,…

  9. NCIS - a Nuclear Criticality Information System (overview)

    SciTech Connect

    Koponen, B.L.; Hampel, V.E.

    1983-07-01

    A Nuclear Criticality Information System (NCIS) is being established at the Lawrence Livermore National Laboratory (LLNL) in order to serve personnel responsible for safe storage, transport, and handling of fissile materials and those concerned with the evaluation and analysis of nuclear, critical experiments. Public concern for nuclear safety provides the incentive for improved access to nuclear safety information.

  10. Dial: A New Campus Information Access System

    ERIC Educational Resources Information Center

    Saffian, Steven R.

    1973-01-01

    The author describes a new campus communication system known as the Digital Information Access Line (DIAL) that disseminates taped information via telephone to students, staff, and faculty in the University Community. Dial access, a simple concept of educational technology, allows remote access at will to audio or visual material stored in a…

  11. Health care services, information systems & sustainability.

    PubMed

    Hovenga, Evelyn J S

    2010-01-01

    This chapter gives an educational overview of: * many competing characteristics within national health systems * national primary information and knowledge flows between health care entities * the role of information technologies in assisting health organizations become sustainable enterprises * the business of maintaining healthy populations for any nation * desirable e-health strategy objectives.

  12. AEROMETRIC INFORMATION RETRIEVAL SYSTEM (AIRS) - GRAPHICS

    EPA Science Inventory

    Aerometric Information Retrieval System (AIRS) is a computer-based repository of information about airborne pollution in the United States and various World Health Organization (WHO) member countries. AIRS is administered by the U.S. Environmental Protection Agency, and runs on t...

  13. Management Information Gleaned from Automated Library Systems.

    ERIC Educational Resources Information Center

    Hawks, Carol Pitts

    1988-01-01

    Discussion of the need for automated library systems to provide management information to aid in decision making focuses on the automatic generation of reports. Examples of management information generated in collection development, acquisitions and serials, cataloging, online catalogs and circulation are described as well as possible uses of this…

  14. Distributing Executive Information Systems through Networks.

    ERIC Educational Resources Information Center

    Penrod, James I.; And Others

    1993-01-01

    Many colleges and universities will soon adopt distributed systems for executive information and decision support. Distribution of shared information through computer networks will improve decision-making processes dramatically on campuses. Critical success factors include administrative support, favorable organizational climate, ease of use,…

  15. Information Systems Enrollments: Challenges and Strategies

    ERIC Educational Resources Information Center

    Granger, Mary J.; Dick, Geoffrey; Jacobson, Carolyn McKinnell; Van Slyke, Craig

    2007-01-01

    Since the late 1990s, enrollments in Information Technology and Information Systems-related academic programs have declined sharply. This paper addresses possible causes of the enrollment decline, and some of the "myths" regarding careers in IT/IS are dispelled. A number of efforts underway at various universities and professional organizations in…

  16. AEROMETRIC INFORMATION RETRIEVAL SYSTEM (AIRS) - GRAPHICS

    EPA Science Inventory

    Aerometric Information Retrieval System (AIRS) is a computer-based repository of information about airborne pollution in the United States and various World Health Organization (WHO) member countries. AIRS is administered by the U.S. Environmental Protection Agency, and runs on t...

  17. Cosmos: An Information Retrieval System that Works.

    ERIC Educational Resources Information Center

    Clay, Katherine; Grossman, Alvin

    1980-01-01

    Briefly described is the County of San Mateo Online System (COSMOS) which was developed and is used by the San Mateo Educational Resources Center (SMERC) to access the Educational Resources Information Center (ERIC) and Fugitive Information Data Organizer (FIDO) databases as well as the curriculum guides housed at SMERC. (TG)

  18. The New Generation of Information Systems.

    ERIC Educational Resources Information Center

    Grunwald, Peter

    1990-01-01

    A new generation of home-use electronic information systems could help transform American schooling. These services reach beyond computer enthusiasts, using various combinations of mass marketing techniques, attractive graphics, easy-to-use controls, localized information, low-cost access, and dedicated terminals. Representative samples include…

  19. Information Systems Enrollments: Challenges and Strategies

    ERIC Educational Resources Information Center

    Granger, Mary J.; Dick, Geoffrey; Jacobson, Carolyn McKinnell; Van Slyke, Craig

    2007-01-01

    Since the late 1990s, enrollments in Information Technology and Information Systems-related academic programs have declined sharply. This paper addresses possible causes of the enrollment decline, and some of the "myths" regarding careers in IT/IS are dispelled. A number of efforts underway at various universities and professional organizations in…

  20. The New Generation of Information Systems.

    ERIC Educational Resources Information Center

    Grunwald, Peter

    1990-01-01

    A new generation of home-use electronic information systems could help transform American schooling. These services reach beyond computer enthusiasts, using various combinations of mass marketing techniques, attractive graphics, easy-to-use controls, localized information, low-cost access, and dedicated terminals. Representative samples include…

  1. A Hypermedia Information System for Aviation.

    ERIC Educational Resources Information Center

    Hartzell, Karin M.

    The Hypermedia Information System (HIS) is being developed under the auspices of the Federal Aviation Administration (FAA) Office of Aviation Medicine's (AAM) Human Factors in Aviation Maintenance (HFAM) research program. The goal of the hypermedia project is to create new tools and methods for aviation-related information storage and retrieval.…

  2. Identification of two functional regions in Fis: the N-terminus is required to promote Hin-mediated DNA inversion but not lambda excision.

    PubMed Central

    Osuna, R; Finkel, S E; Johnson, R C

    1991-01-01

    The Fis protein of E. coli binds to a recombinational enhancer sequence that is required to stimulate Hin-mediated DNA inversion. Fis is also required for efficient lambda prophase excision in vivo. The properties of mutant Fis proteins were examined in vivo and in vitro with respect to their stimulatory effects on these two different site-specific DNA recombination reactions. Both recombination reactions are dramatically affected by mutations altering a helix-turn-helix DNA binding motif located near the Fis C-terminus (residues 74-93). These mutations invariably decrease DNA binding affinity and some cause reduced DNA bending. Mutations in the Fis N-terminal region reduce or abolish the stimulation of Hin-mediated DNA recombination by Fis, but have little or no effect on DNA binding or lambda excision. We conclude that there are at least two functionally distinct domains in Fis: a C-terminal DNA binding region that is required for promoting both DNA recombination reactions and an N-terminal region that is uniquely required for Hin-mediated inversion. Images PMID:1851089

  3. Integrated information systems: tools for affiliation.

    PubMed

    Katz, P A

    1995-05-01

    The development of healthcare information systems as tools to facilitate business success traditionally has focused on a single profit center. The cataclysmic changes that are reshaping American healthcare have accelerated the affiliation of provider entities to form systems that have broader geographic coverage, deliver a larger portion of the provider continuum of care, and are more attractive partners for purchasers of healthcare services. Integrated and/or standardized information system technologies can provide great benefit in containing costs and optimizing quality among partners resulting from healthcare mergers and acquisitions as the new entity positions itself to increase market share and enhance its bottom line. Graduate Health System (GHS) in the Philadelphia area has demonstrated the efficacy of its investment to build a system-wide information network that delivers multiple standardized, integrated systems for both the financial and operational advantage of all component institutions. Building on its patient information system as the centerpiece of its information strategy, GHS has deployed a variety of tools across its network infrastructure that have brought new capabilities and savings to its member hospitals. In light of some of GHS's successes, other hospitals and healthcare systems may be able to re-create similar savings and efficiencies by applying like strategies in cooperation with their affiliated partners.

  4. Evaluation of health information systems research in information systems research: A meta-analysis.

    PubMed

    Haried, Peter; Claybaugh, Craig; Dai, Hua

    2017-04-01

    Given the importance of the health-care industry and the promise of health information systems, researchers are encouraged to build on the shoulders of giants as the saying goes. The health information systems field has a unique opportunity to learn from and extend the work that has already been done by the highly correlated information systems field. As a result, this research article presents a past, present and future meta-analysis of health information systems research in information systems journals over the 2000-2015 time period. Our analysis reviewed 126 articles on a variety of topics related to health information systems research published in the "Senior Scholars" list of the top eight ranked information systems academic journals. Across the selected information systems academic journals, our findings compare research methodologies applied, health information systems topic areas investigated and research trends. Interesting results emerge in the range and evolution of health information systems research and opportunities for health information systems researchers and practitioners to consider moving forward.

  5. The architecture of enterprise hospital information system.

    PubMed

    Lu, Xudong; Duan, Huilong; Li, Haomin; Zhao, Chenhui; An, Jiye

    2005-01-01

    Because of the complexity of the hospital environment, there exist a lot of medical information systems from different vendors with incompatible structures. In order to establish an enterprise hospital information system, the integration among these heterogeneous systems must be considered. Complete integration should cover three aspects: data integration, function integration and workflow integration. However most of the previous design of architecture did not accomplish such a complete integration. This article offers an architecture design of the enterprise hospital information system based on the concept of digital neural network system in hospital. It covers all three aspects of integration, and eventually achieves the target of one virtual data center with Enterprise Viewer for users of different roles. The initial implementation of the architecture in the 5-year Digital Hospital Project in Huzhou Central hospital of Zhejiang Province is also described.

  6. Early-EOS data and information system

    NASA Technical Reports Server (NTRS)

    Ludwig, George H.; Hunolt, Gregory W.

    1991-01-01

    NASA's Earth Observing System (EOS), an integral part of the U.S. Global Change Research Program, will provide simultaneous observations from a suite of instruments in low-earth orbit. The EOS Data and Information System (EOSDIS) will handle the data from those instruments, as well as provide access to observations and related information from other earth science missions. The Early-EOSDIS Program will provide initial improved support for global change research by building upon present capabilities and data, and will establish a working prototype EOSDIS for selected archiving, distribution, and information management functions by mid-1994.

  7. Early-EOS data and information system

    NASA Technical Reports Server (NTRS)

    Ludwig, George H.; Hunolt, Gregory W.

    1991-01-01

    NASA's Earth Observing System (EOS), an integral part of the U.S. Global Change Research Program, will provide simultaneous observations from a suite of instruments in low-earth orbit. The EOS Data and Information System (EOSDIS) will handle the data from those instruments, as well as provide access to observations and related information from other earth science missions. The Early-EOSDIS Program will provide initial improved support for global change research by building upon present capabilities and data, and will establish a working prototype EOSDIS for selected archiving, distribution, and information management functions by mid-1994.

  8. MINIS: Multipurpose Interactive NASA Information System

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The Multipurpose Interactive NASA Information Systems (MINIS) was developed in response to the need for a data management system capable of operation on several different minicomputer systems. The desired system had to be capable of performing the functions of a LANDSAT photo descriptive data retrieval system while remaining general in terms of other acceptable user definable data bases. The system also had to be capable of performing data base updates and providing user-formatted output reports. The resultant MINI System provides all of these capabilities and several other features to complement the data management system. The MINI System is currently implemented on two minicomputer systems and is in the process of being installed on another minicomputer system. The MINIS is operational on four different data bases.

  9. Hypertext and hypermedia systems in information retrieval

    NASA Technical Reports Server (NTRS)

    Kaye, K. M.; Kuhn, A. D.

    1992-01-01

    This paper opens with a brief history of hypertext and hypermedia in the context of information management during the 'information age.' Relevant terms are defined and the approach of the paper is explained. Linear and hypermedia information access methods are contrasted. A discussion of hyperprogramming in the handling of complex scientific and technical information follows. A selection of innovative hypermedia systems is discussed. An analysis of the Clinical Practice Library of Medicine NASA STI Program hypermedia application is presented. The paper concludes with a discussion of the NASA STI Program's future hypermedia project plans.

  10. Hypertext and hypermedia systems in information retrieval

    NASA Technical Reports Server (NTRS)

    Kaye, K. M.; Kuhn, A. D.

    1992-01-01

    This paper opens with a brief history of hypertext and hypermedia in the context of information management during the 'information age.' Relevant terms are defined and the approach of the paper is explained. Linear and hypermedia information access methods are contrasted. A discussion of hyperprogramming in the handling of complex scientific and technical information follows. A selection of innovative hypermedia systems is discussed. An analysis of the Clinical Practice Library of Medicine NASA STI Program hypermedia application is presented. The paper concludes with a discussion of the NASA STI Program's future hypermedia project plans.

  11. Information survey for microcomputer systems integration

    SciTech Connect

    Hake, K.A.

    1991-12-01

    One goal of the PM-AIM is to provide US Army Project Managers (PMs) and Project Executive Officers (PEOs) with a fundamental microcomputing resource to help perform acquisition information management and its concomitant reporting requirements. Providing key application software represents one means of accomplishing this goal. This workstation would furnish a broad range of capabilities needed in the PM and PEO office settings as well as software tools for specific project management and acquisition information. Although still in the conceptual phase, the practical result of this exercise in systems integration will likely be a system called the Project Manager`s Information System (PMIS) or the AIM workstation. It would include such software as, Project Manager`s System Software (PMSS), Defense Acquisition Executive Summary (DAES), and Consolidated Acquisition Reporting System (CARS) and would conform to open systems architecture as accepted by the Department of Defense. ORNL has assisted PM-AIM in the development of technology ideas for the PMIS workstation concept. This paper represents the compilation of information gained during this process. This information is presented as a body of knowledge (or knowledge domain) defining the complex technology of microcomputing. The concept of systems integration or tying together all hardware and software components reflects the nature of PM-AIM`s task in attempting to field a PMIS or AIM workstation.

  12. Information survey for microcomputer systems integration

    SciTech Connect

    Hake, K.A.

    1991-12-01

    One goal of the PM-AIM is to provide US Army Project Managers (PMs) and Project Executive Officers (PEOs) with a fundamental microcomputing resource to help perform acquisition information management and its concomitant reporting requirements. Providing key application software represents one means of accomplishing this goal. This workstation would furnish a broad range of capabilities needed in the PM and PEO office settings as well as software tools for specific project management and acquisition information. Although still in the conceptual phase, the practical result of this exercise in systems integration will likely be a system called the Project Manager's Information System (PMIS) or the AIM workstation. It would include such software as, Project Manager's System Software (PMSS), Defense Acquisition Executive Summary (DAES), and Consolidated Acquisition Reporting System (CARS) and would conform to open systems architecture as accepted by the Department of Defense. ORNL has assisted PM-AIM in the development of technology ideas for the PMIS workstation concept. This paper represents the compilation of information gained during this process. This information is presented as a body of knowledge (or knowledge domain) defining the complex technology of microcomputing. The concept of systems integration or tying together all hardware and software components reflects the nature of PM-AIM's task in attempting to field a PMIS or AIM workstation.

  13. Information propagation in isolated quantum systems

    NASA Astrophysics Data System (ADS)

    Luitz, David J.; Bar Lev, Yevgeny

    2017-07-01

    Entanglement growth and out-of-time-order correlators (OTOC) are used to assess the propagation of information in isolated quantum systems. In this work, using large scale exact time evolution we show that for weakly disordered nonintegrable systems information propagates behind a ballistically moving front, and the entanglement entropy growths linearly in time. For stronger disorder the motion of the information front is algebraic and subballistic and is characterized by an exponent, which depends on the strength of the disorder, similarly to the sublinear growth of the entanglement entropy. We show that the dynamical exponent associated with the information front coincides with the exponent of the growth of the entanglement entropy for both weak and strong disorder. We also demonstrate that the temporal dependence of the OTOC is characterized by a fast nonexponential growth, followed by a slow saturation after the passage of the information front. Finally, we discuss the implications of this behavioral change on the growth of the entanglement entropy.

  14. Low-Force DNA Condensation and Discontinuous High-Force Decondensation Reveal a Loop-Stabilizing Function of the Protein Fis

    NASA Astrophysics Data System (ADS)

    Skoko, Dunja; Yan, Jie; Johnson, Reid C.; Marko, John F.

    2005-11-01

    We report single-DNA-stretching experiments showing that the protein Fis, an abundant bacterial chromosome protein of E. coli, mediates a dramatic DNA condensation to zero length. This condensation occurs abruptly when DNA tension is reduced below a protein-concentration-dependent threshold f*<1pN. Following condensation, reopening under larger forces proceeds via a series of discrete jumps, indicating that Fis is able to stabilize DNA crossings. Our experiments suggest that Fis may play a role in vivo stabilizing the “loop-domain” structure of the bacterial chromosome.

  15. On Roles of Models in Information Systems

    NASA Astrophysics Data System (ADS)

    Sølvberg, Arne

    The increasing penetration of computers into all aspects of human activity makes it desirable that the interplay among software, data and the domains where computers are applied is made more transparent. An approach to this end is to explicitly relate the modeling concepts of the domains, e.g., natural science, technology and business, to the modeling concepts of software and data. This may make it simpler to build comprehensible integrated models of the interactions between computers and non-computers, e.g., interaction among computers, people, physical processes, biological processes, and administrative processes. This chapter contains an analysis of various facets of the modeling environment for information systems engineering. The lack of satisfactory conceptual modeling tools seems to be central to the unsatisfactory state-of-the-art in establishing information systems. The chapter contains a proposal for defining a concept of information that is relevant to information systems engineering.

  16. Legal Medicine Information System using CDISC ODM.

    PubMed

    Kiuchi, Takahiro; Yoshida, Ken-ichi; Kotani, Hirokazu; Tamaki, Keiji; Nagai, Hisashi; Harada, Kazuki; Ishikawa, Hirono

    2013-11-01

    We have developed a new database system for forensic autopsies, called the Legal Medicine Information System, using the Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM). This system comprises two subsystems, namely the Institutional Database System (IDS) located in each institute and containing personal information, and the Central Anonymous Database System (CADS) located in the University Hospital Medical Information Network Center containing only anonymous information. CDISC ODM is used as the data transfer protocol between the two subsystems. Using the IDS, forensic pathologists and other staff can register and search for institutional autopsy information, print death certificates, and extract data for statistical analysis. They can also submit anonymous autopsy information to the CADS semi-automatically. This reduces the burden of double data entry, the time-lag of central data collection, and anxiety regarding legal and ethical issues. Using the CADS, various studies on the causes of death can be conducted quickly and easily, and the results can be used to prevent similar accidents, diseases, and abuse.

  17. Developing an information systems strategy for nursing.

    PubMed

    Callanan, K M; Hughes, S J

    1995-01-01

    With the rapidly changing health care environment and information technology advances, organizations need to engage in strategic, planned change in order to allocate limited resources, achieve the organization's goals, and fulfill its mission [1]. One of the most important aspects of the organization's planned strategies for change concerns the information systems. The involvement of the nursing department in this process is critical. This poster presentation will communicate how nurses can develop an information systems strategic plan that will enable them to play an active role as contributors and vital participants in the strategic and business planning processes for information systems. This information systems strategy for nursing will: a) provide direction and purpose, b) guide nursing in identifying the kinds of information technology needed, c) assist in timely implementation of a system that supports nursing, and d) identify desired outcomes and benefits of an information system. The nursing information systems plan must be built on, and support, the organization's mission and business plan and integrate into the over-all information systems plans [2]. Components of the nursing strategic plan include the nursing mission statement and vision, an assessment of the current environment to identify supporting technology needed to achieve the nursing vision, expectations/anticipated outcomes, environmental considerations, and special staffing/expertise considerations. The nursing vision and mission statement is an articulation of the overall direction and purpose of the nursing organization. An assessment of the nursing organization, problem areas, opportunities for growth, the physical environment, existing systems, communications requirements, and resources is carried out to help identify areas where new technologies and automated methods of managing information could be applied. Special staffing and expertise not currently available in the organization, but

  18. Adaptable Information Models in the Global Change Information System

    NASA Astrophysics Data System (ADS)

    Duggan, B.; Buddenberg, A.; Aulenbach, S.; Wolfe, R.; Goldstein, J.

    2014-12-01

    The US Global Change Research Program has sponsored the creation of the Global Change Information System () to provide a web based source of accessible, usable, and timely information about climate and global change for use by scientists, decision makers, and the public. The GCIS played multiple roles during the assembly and release of the Third National Climate Assessment. It provided human and programmable interfaces, relational and semantic representations of information, and discrete identifiers for various types of resources, which could then be manipulated by a distributed team with a wide range of specialties. The GCIS also served as a scalable backend for the web based version of the report. In this talk, we discuss the infrastructure decisions made during the design and deployment of the GCIS, as well as ongoing work to adapt to new types of information. Both a constrained relational database and an open ended triple store are used to ensure data integrity while maintaining fluidity. Using natural primary keys allows identifiers to propagate through both models. Changing identifiers are accomodated through fine grained auditing and explicit mappings to external lexicons. A practical RESTful API is used whose endpoints are also URIs in an ontology. Both the relational schema and the ontology are maleable, and stability is ensured through test driven development and continuous integration testing using modern open source techniques. Content is also validated through continuous testing techniques. A high degres of scalability is achieved through caching.

  19. Complementarity of Historic Building Information Modelling and Geographic Information Systems

    NASA Astrophysics Data System (ADS)

    Yang, X.; Koehl, M.; Grussenmeyer, P.; Macher, H.

    2016-06-01

    In this paper, we discuss the potential of integrating both semantically rich models from Building Information Modelling (BIM) and Geographical Information Systems (GIS) to build the detailed 3D historic model. BIM contributes to the creation of a digital representation having all physical and functional building characteristics in several dimensions, as e.g. XYZ (3D), time and non-architectural information that are necessary for construction and management of buildings. GIS has potential in handling and managing spatial data especially exploring spatial relationships and is widely used in urban modelling. However, when considering heritage modelling, the specificity of irregular historical components makes it problematic to create the enriched model according to its complex architectural elements obtained from point clouds. Therefore, some open issues limiting the historic building 3D modelling will be discussed in this paper: how to deal with the complex elements composing historic buildings in BIM and GIS environment, how to build the enriched historic model, and why to construct different levels of details? By solving these problems, conceptualization, documentation and analysis of enriched Historic Building Information Modelling are developed and compared to traditional 3D models aimed primarily for visualization.

  20. Virtualization Technologies in Information Systems Education

    ERIC Educational Resources Information Center

    Lunsford, Dale L.

    2009-01-01

    Information systems educators must balance the need to protect the stability, availability, and security of computer laboratories with the learning objectives of various courses. In advanced courses where students need to install, configure, and otherwise manipulate application and operating system settings, this is especially problematic as these…

  1. Delivering Training for Highly Demanding Information Systems

    ERIC Educational Resources Information Center

    Norton, Andrew Lawrence; Coulson-Thomas, Yvette May; Coulson-Thomas, Colin Joseph; Ashurst, Colin

    2012-01-01

    Purpose: There is a lack of research covering the training requirements of organisations implementing highly demanding information systems (HDISs). The aim of this paper is to help in the understanding of appropriate training requirements for such systems. Design/methodology/approach: This research investigates the training delivery within a…

  2. Divulging Personal Information within Learning Analytics Systems

    ERIC Educational Resources Information Center

    Ifenthaler, Dirk; Schumacher, Clara

    2015-01-01

    The purpose of this study was to investigate if students are prepared to release any personal data in order to inform learning analytics systems. Besides the well-documented benefits of learning analytics, serious concerns and challenges are associated with the application of these data driven systems. Most notably, empirical evidence regarding…

  3. Natural Resource Information System. Remote Sensing Studies.

    ERIC Educational Resources Information Center

    Leachtenauer, J.; And Others

    A major design objective of the Natural Resource Information System entailed the use of remote sensing data as an input to the system. Potential applications of remote sensing data were therefore reviewed and available imagery interpreted to provide input to a demonstration data base. A literature review was conducted to determine the types and…

  4. A Low Cost Course Information Syndication System

    ERIC Educational Resources Information Center

    Ajayi, A. O.; Olajubu, E. A.; Bello, S. A.; Soriyan, H. A.; Obamuyide, A. V.

    2011-01-01

    This study presents a cost effective, reliable, and convenient mobile web-based system to facilitate the dissemination of course information to students, to support interaction that goes beyond the classroom. The system employed the Really Simple Syndication (RSS) technology and was developed using Rapid Application Development (RAD) methodology.…

  5. Reaping the Benefits of Medical Information Systems.

    ERIC Educational Resources Information Center

    Wong, E. Tin; Abendroth, Tomas W.

    1996-01-01

    This paper proposes that physicians' use of computerized medical information systems in the practice of medicine can assist delivery of cost-effective, high-quality patient care and help expand clinical research. However, benefits can be realized only if clinicians participate in system development and implementation and if senior institutional…

  6. Promoting Geographic Information System Usage across Campus

    ERIC Educational Resources Information Center

    Spiegel, Shaun; Kinikin, Janae

    2004-01-01

    In this article the authors discuss how they implemented and promoted Geographic Information System (GIS) applications at Weber State University (WSU), a four-year public institution with two campuses. GIS is a type of computer system made of hardware, software, and data that allows the mapping of spatially related layers that have a common…

  7. A Low Cost Course Information Syndication System

    ERIC Educational Resources Information Center

    Ajayi, A. O.; Olajubu, E. A.; Bello, S. A.; Soriyan, H. A.; Obamuyide, A. V.

    2011-01-01

    This study presents a cost effective, reliable, and convenient mobile web-based system to facilitate the dissemination of course information to students, to support interaction that goes beyond the classroom. The system employed the Really Simple Syndication (RSS) technology and was developed using Rapid Application Development (RAD) methodology.…

  8. Chemical Biological Emergency Management Information System

    SciTech Connect

    2004-06-15

    CB-EMIS is designed to provide information and analysis to transit system operators and emergency responders in the event of a chemical attack on a subway system. The software inforporates detector data, video images, train data, meteorological data, and above- and below-ground plume dispersion models, hight of the liquid level.

  9. Development of medical data information systems

    NASA Technical Reports Server (NTRS)

    Anderson, J.

    1971-01-01

    Computerized storage and retrieval of medical information is discussed. Tasks which were performed in support of the project are: (1) flight crew health stabilization computer system, (2) medical data input system, (3) graphic software development, (4) lunar receiving laboratory support, and (5) Statos V printer/plotter software development.

  10. Information Feedback Systems (IFS) and Educational Goals.

    ERIC Educational Resources Information Center

    White, William F.

    An information feedback system for use in evaluating an educational program is described, and its effectiveness in evaluating the Follow Through program and its use in relation to the Iowa Tests of Basic Skills are discussed. The systems approach to program evaluation consists of objectives clarification, decision making, and program planning. In…

  11. Delivering Training for Highly Demanding Information Systems

    ERIC Educational Resources Information Center

    Norton, Andrew Lawrence; Coulson-Thomas, Yvette May; Coulson-Thomas, Colin Joseph; Ashurst, Colin

    2012-01-01

    Purpose: There is a lack of research covering the training requirements of organisations implementing highly demanding information systems (HDISs). The aim of this paper is to help in the understanding of appropriate training requirements for such systems. Design/methodology/approach: This research investigates the training delivery within a…

  12. Virtualization Technologies in Information Systems Education

    ERIC Educational Resources Information Center

    Lunsford, Dale L.

    2009-01-01

    Information systems educators must balance the need to protect the stability, availability, and security of computer laboratories with the learning objectives of various courses. In advanced courses where students need to install, configure, and otherwise manipulate application and operating system settings, this is especially problematic as these…

  13. Promoting Geographic Information System Usage across Campus

    ERIC Educational Resources Information Center

    Spiegel, Shaun; Kinikin, Janae

    2004-01-01

    In this article the authors discuss how they implemented and promoted Geographic Information System (GIS) applications at Weber State University (WSU), a four-year public institution with two campuses. GIS is a type of computer system made of hardware, software, and data that allows the mapping of spatially related layers that have a common…

  14. Natural Resource Information System. Remote Sensing Studies.

    ERIC Educational Resources Information Center

    Leachtenauer, J.; And Others

    A major design objective of the Natural Resource Information System entailed the use of remote sensing data as an input to the system. Potential applications of remote sensing data were therefore reviewed and available imagery interpreted to provide input to a demonstration data base. A literature review was conducted to determine the types and…

  15. Organization of Communication in Information Systems.

    ERIC Educational Resources Information Center

    Datsenko, V. P.; Zaytsev, N. G.

    Organization of communication between the center of an automated system of information exchange and the subscribers to the system is described. The three requirements are: (1) those technical communication means must be chosen which will provide effective and convenient avenues for calls from the subscribers to the center, (2) the required…

  16. Geographical information systems and tropical medicine

    PubMed Central

    KHAN, O. A.; DAVENHALL, W.; ALI, M.; CASTILLO-SALGADO, C.; VAZQUEZ-PROKOPEC, G.; KITRON, U.; SOARES MAGALHÃES, R. J.; CLEMENTS, A. C. A.

    2013-01-01

    In terms of their applicability to the field of tropical medicine, geographical information systems (GIS) have developed enormously in the last two decades. This article reviews some of the pertinent and representative applications of GIS, including the use of such systems and remote sensing for the mapping of Chagas disease and human helminthiases, the use of GIS in vaccine trials, and the global applications of GIS for health-information management, disease epidemiology, and pandemic planning. The future use of GIS as a decision-making tool and some barriers to the widespread implementation of such systems in developing settings are also discussed. PMID:20659391

  17. A Comparison of Information System Development Methodologies.

    DTIC Science & Technology

    1987-12-01

    r Dll -ft lU 5? R COMPARISON OF INFORMATION SYSTEM DEYELOPMENT IETHOOOLOGXES(U) AIR FORCE ]NST OF TECH IGHMT-PRTTERSON RFI 0ON SCHOOL OF SYSTEMS AND...DEVELOPMENT METHODOLJOGI ES THESIS Steven D. Branch Captain, USAF AFIT/GI R /LSR/87D-1 ...................i TON STTEM " A Approyed for public relecog4i...AFIT/GIR/LSR/87D- 1 A COMPARISON OF INFORMATION SYSTEM - DEVELOPMENT METHODOLOGIES .> THESIS ’ r ~( D~9ii Captain, USAF% AFIT/GIR/LSR/8?D-1 FE 0

  18. Space Station Information System integrated communications concept

    NASA Technical Reports Server (NTRS)

    Muratore, J.; Bigham, J.; Whitelaw, V.; Marker, W.

    1987-01-01

    This paper presents a model for integrated communications within the Space Station Information System (SSIS). The SSIS is generally defined as the integrated set of space and ground information systems and networks which will provide required data services to the Space Station flight crew, ground operations personnel, and customer communities. This model is based on the International Standards Organization (ISO) layered model for Open Systems Interconnection (OSI). The requirements used to develop the model are presented, and the various elements of the model described.

  19. Engineering Information Management Systems survey: CADCAM-002

    SciTech Connect

    Fletcher, S.K.

    1984-09-01

    An immediate goal of CAD/CAM integration in the DOE Nuclear Weapons Complex is automated data transfer/translation between the design, analysis, and manufacturing functions. A longer range goal is to use CAD derived geometric part descriptions as official product definition, rather than the current drawing based product definition. The Engineering Information Management System is described loosely as that software system which performs all the needed functions related to archiving and accessing computer based product definition. Major ingredients of such a system include automated data management, neutral format, engineering databases, information models, and translators. This report surveys the current state of the art in these five areas.

  20. An update on laboratory information management systems.

    PubMed

    McDowall, R D

    1993-01-01

    The realization that a laboratory is an effective information generator within an organization has begun to influence the functions required of a laboratory information management system (LIMS): different laboratories require different functions. The trends in general computing such as open systems, adoption of relational database technology, and the use of more efficient development languages, are also impacting on the development of LIMS. These trends, plus the development of standards for both LIMS and analytical data interchange, will allow the development of systems that are quicker to implement, easier to maintain and meet the business need better.

  1. Space Station Information System integrated communications concept

    NASA Technical Reports Server (NTRS)

    Muratore, J.; Bigham, J.; Whitelaw, V.; Marker, W.

    1987-01-01

    This paper presents a model for integrated communications within the Space Station Information System (SSIS). The SSIS is generally defined as the integrated set of space and ground information systems and networks which will provide required data services to the Space Station flight crew, ground operations personnel, and customer communities. This model is based on the International Standards Organization (ISO) layered model for Open Systems Interconnection (OSI). The requirements used to develop the model are presented, and the various elements of the model described.

  2. Geographic information system/watershed model interface

    USGS Publications Warehouse

    Fisher, Gary T.

    1989-01-01

    Geographic information systems allow for the interactive analysis of spatial data related to water-resources investigations. A conceptual design for an interface between a geographic information system and a watershed model includes functions for the estimation of model parameter values. Design criteria include ease of use, minimal equipment requirements, a generic data-base management system, and use of a macro language. An application is demonstrated for a 90.1-square-kilometer subbasin of the Patuxent River near Unity, Maryland, that performs automated derivation of watershed parameters for hydrologic modeling.

  3. Data protection in health information systems (HIS).

    PubMed

    Griesser, G

    1989-01-01

    Information and communication systems in a health (care) environment are risky systems as the data processed, transmitted, stored and retrieved are person-related. An unjustified disclosure may compromise the individual's personal or social life. Therefore these systems must be subject to carefully designed and implemented protection procedures guaranteeing the correct use of those data, corresponding in the medical sphere with the ancient Oath of Hippokrates, as well as the preservation of their correctness, completeness etc., as requested by legal regulations valid for the location of the respective computer-aided information system. The same is true for the manual handling of person-related health data by conventional methods. In any case, the data subject's right of informational self determination must be taken into account.

  4. The Consumer Health Information System Adoption Model.

    PubMed

    Monkman, Helen; Kushniruk, Andre W

    2015-01-01

    Derived from overlapping concepts in consumer health, a consumer health information system refers to any of the broad range of applications, tools, and educational resources developed to empower consumers with knowledge, techniques, and strategies, to manage their own health. As consumer health information systems become increasingly popular, it is important to explore the factors that impact their adoption and success. Accumulating evidence indicates a relationship between usability and consumers' eHealth Literacy skills and the demands consumer HISs place on their skills. Here, we present a new model called the Consumer Health Information System Adoption Model, which depicts both consumer eHealth literacy skills and system demands on eHealth literacy as moderators with the potential to affect the strength of relationship between usefulness and usability (predictors of usage) and adoption, value, and successful use (actual usage outcomes). Strategies for aligning these two moderating factors are described.

  5. NASA metrology information system: A NEMS subsystem

    NASA Technical Reports Server (NTRS)

    German, E. S., Jr.; Kern, F. A.; Yow, R. P.; Peterson, E.

    1984-01-01

    the NASA Metrology Information Systems (NMIS) is being developed as a standardized tool in managing the NASA field Center's instrument calibration programs. This system, as defined by the NASA Metrology and Calibration Workshop, will function as a subsystem of the newly developed NASA Equipment Management System (NEMS). The Metrology Information System is designed to utilize and update applicable NEMS data fields for controlled property and to function as a stand alone system for noncontrolled property. The NMIS provides automatic instrument calibration recall control, instrument historical performance data storage and analysis, calibration and repair labor and parts cost data, and instrument user and location data. Nineteen standardized reports were developed to analyze calibration system operations.

  6. Clinical information systems market - an insider's view.

    PubMed

    Manjoney, Richard

    2004-12-01

    Clinical information systems that provide electronic charting and documentation have been commercially available for over 15 years. These systems provide varying degrees of automation to flowsheets, forms, notes, worklists, care plans, and medication administration records. Although there are many benefits that an electronic system brings, such as accessibility, legibility, process adherence, and data mining, the market has been slow to adopt these systems. A variety of historical factors can explain the lack of widespread system implementations. Survey data of CEOs/CIOs from the Healthcare Information and Management Systems Society (HIMSS) shows promising data that clinically oriented applications will receive high prioritization in near term planning. Will this prioritization materialize in actual implementations? Market drivers appear to be in place to predict an increase in sales and implementations.

  7. Information Management System for Site Remediation Efforts.

    PubMed

    Laha; Mukherjee; Nebhrajani

    2000-05-01

    / Environmental regulatory agencies are responsible for protecting human health and the environment in their constituencies. Their responsibilities include the identification, evaluation, and cleanup of contaminated sites. Leaking underground storage tanks (USTs) constitute a major source of subsurface and groundwater contamination. A significant portion of a regulatory body's efforts may be directed toward the management of UST-contaminated sites. In order to manage remedial sites effectively, vast quantities of information must be maintained, including analytical dataon chemical contaminants, remedial design features, and performance details. Currently, most regulatory agencies maintain such information manually. This makes it difficult to manage the data effectively. Some agencies have introduced automated record-keeping systems. However, the ad hoc approach in these endeavors makes it difficult to efficiently analyze, disseminate, and utilize the data. This paper identifies the information requirements for UST-contaminated site management at the Waste Cleanup Section of the Department of Environmental Resources Management in Dade County, Florida. It presents a viable design for an information management system to meet these requirements. The proposed solution is based on a back-end relational database management system with relevant tools for sophisticated data analysis and data mining. The database is designed with all tables in the third normal form to ensure data integrity, flexible access, and efficient query processing. In addition to all standard reports required by the agency, the system provides answers to ad hoc queries that are typically difficult to answer under the existing system. The database also serves as a repository of information for a decision support system to aid engineering design and risk analysis. The system may be integrated with a geographic information system for effective presentation and dissemination of spatial data.

  8. [Information system in the cardio polyclinic].

    PubMed

    Mihajlović, Marina; Zivković, Marija

    2014-03-01

    The cardiologic polyclinic information system ensures effective management of business processes in the polyclinic. Medical nurse provides health care to a patient with the support of the information system, which enables recording the patient's identity, admission, participation fee charges, billing for the services provided, patients' orders for noninvasive diagnostic methods, and implementation of diagnostic methods. The nurse enters patient's personal information at every work station, updates the existing records, and has an opportunity to add notes and insights to the results of patient's diagnostic tests and doctors' opinions for patients in the polyclinic. Additionally, the nurse records the services and supplies provided, and these entries are used for billing and service charges. This information is accessible at every work station to authorized persons exclusively. The implementation of the information system enables medical nurses working at the reception desk and in nurses' consulting room to record administrative data and data related to diagnostic analysis at the moment and at the place they happen. A personal password is required to access these data. In this way, the patient admission recording is facilitated, and in case the patient needs to be contacted, communication with him/her is improved, and finally, writing reports and data analysis are simplified. Apart from the advantages, there also are problems such as inadequate staff education and insufficient reliability of the information infrastructure, which if overloaded, can slow down the system, and this is time consuming for both health workers and patients.

  9. The Arbo‑zoonet Information System.

    PubMed

    Di Lorenzo, Alessio; Di Sabatino, Daria; Blanda, Valeria; Cioci, Daniela; Conte, Annamaria; Bruno, Rossana; Sauro, Francesca; Calistri, Paolo; Savini, Lara

    2016-06-30

    The Arbo‑zoonet Information System has been developed as part of the 'International Network for Capacity Building for the Control of Emerging Viral Vector Borne Zoonotic Diseases (Arbo‑zoonet)' project. The project aims to create common knowledge, sharing data, expertise, experiences, and scientific information on West Nile Disease (WND), Crimean‑Congo haemorrhagic fever (CCHF), and Rift Valley fever (RVF). These arthropod‑borne diseases of domestic and wild animals can affect humans, posing great threat to public health. Since November 2011, when the Schmallenberg virus (SBV) has been discovered for the first time in Northern Europe, the Arbo‑zoonet Information System has been used in order to collect information on newly discovered disease and to manage the epidemic emergency. The system monitors the geographical distribution and epidemiological evolution of CCHF, RVF, and WND since 1946. More recently, it has also been deployed to monitor the SBV data. The Arbo‑zoonet Information System includes a web application for the management of the database in which data are stored and a WebGIS application to explore spatial disease distributions, facilitating the epidemiological analysis. The WebGIS application is an effective tool to show and share the information and to facilitate the exchange and dissemination of relevant data among project's participants.

  10. LOGISTIC MANAGEMENT INFORMATION SYSTEM - MANUAL DATA STORAGE AND RETRIEVAL SYSTEM.

    DTIC Science & Technology

    Logistics Management Information System . The procedures are applicable to manual storage and retrieval of all data used in the Logistics Management ... Information System (LMIS) and include the following: (1) Action Officer data source file. (2) Action Officer presentation format file. (3) LMI Coordination

  11. Drug information systems: evolution of benefits with system maturity.

    PubMed

    Leung, Valerie; Hagens, Simon; Zelmer, Jennifer

    2013-01-01

    Benefits from information and communication technology tend to grow over time as system use matures. This study examines pharmacists' experiences with provincial drug information systems (DIS) across Canada. At the time of survey, two provinces had more mature DIS (more than five years) and three provinces had less mature DIS (five years or less).

  12. NASA's Earth Observing System Data and Information System - EOSDIS

    NASA Technical Reports Server (NTRS)

    Ramapriyan, Hampapuram K.

    2011-01-01

    This slide presentation reviews the work of NASA's Earth Observing System Data and Information System (EOSDIS), a petabyte-scale archive of environmental data that supports global climate change research. The Earth Science Data Systems provide end-to-end capabilities to deliver data and information products to users in support of understanding the Earth system. The presentation contains photographs from space of recent events, (i.e., the effects of the tsunami in Japan, and the wildfires in Australia.) It also includes details of the Data Centers that provide the data to EOSDIS and Science Investigator-led Processing Systems. Information about the Land, Atmosphere Near-real-time Capability for EOS (LANCE) and some of the uses that the system has made possible are reviewed. Also included is information about how to access the data, and evolutionary plans for the future of the system.

  13. Improvements to information management systems simulator

    NASA Technical Reports Server (NTRS)

    Bilek, R. W.

    1972-01-01

    The performance of personnel in the augmentation and improvement of the interactive IMSIM information management simulation model is summarized. With this augmented model, NASA now has even greater capabilities for the simulation of computer system configurations, data processing loads imposed on these configurations, and executive software to control system operations. Through these simulations, NASA has an extremely cost effective capability for the design and analysis of computer-based data management systems.

  14. Experience with Nuclear Medicine Information System

    PubMed Central

    Volkan-Salanci, Bilge; Şahin, Figen; Babekoğlu, Vahide; Uğur, Ömer

    2012-01-01

    Objective: Radiology information system (RIS) is basically evolved for the need of radiologists and ignores the vital steps needed for a proper work flow of Nuclear Medicine Department. Moreover, CT/MRI oriented classical PACS systems are far from satisfying Nuclear Physicians like storing dynamic data for reprocessing and quantitative analysis of colored images. Our purpose was to develop a workflow based Nuclear Medicine Information System (NMIS) that fulfills the needs of Nuclear Medicine Department and its integration to hospital PACS system. Material and Methods: Workflow in NMIS uses HL7 (health level seven) and steps include, patient scheduling and retrieving information from HIS (hospital information system), radiopharmacy, acquisition, digital reporting and approval of the reports using Nuclear Medicine specific diagnostic codes. Images and dynamic data from cameras of are sent to and retrieved from PACS system (Corttex©) for reprocessing and quantitative analysis. Results: NMIS has additional functions to the RIS such as radiopharmaceutical management program which includes stock recording of both radioactive and non-radioactive substances, calculation of the radiopharmaceutical dose for individual patient according to body weight and maximum permissible activity, and calculation of radioactivity left per unit volume for each radionuclide according their half lives. Patient scheduling and gamma camera patient work list settings were arranged according to specific Nuclear Medicine procedures. Nuclear Medicine images and reports can be retrieved and viewed from HIS. Conclusion: NMIS provides functionality to standard RIS and PACS system according to the needs of Nuclear Medicine. Conflict of interest:None declared. PMID:23487446

  15. TQM information systems: an elusive goal.

    PubMed

    Collins, L W

    1994-11-01

    An information support system is needed to locate, integrate, and present data to track and communicate the progress of quality efforts. Bethesda Hospital's executive information system (EIS) has been developed and refined on an ongoing basis to support a variety of total quality management (TQM) functions. One basic area where information systems must support TQM is in the availability of data for use by process improvement teams; without such support the entire process of data gathering and analysis would often be prohibitively difficult. Teams also need data to evaluate the results of changes to the improved process. Once core and critical work processes are identified and improvement targets are set, a system of interlinking measures can be established to allow the monitoring and improvement of the processes. Models have been used to support and facilitate design or redesign of major processes. The purpose of this decision support system is to monitor a department's core processes and to provide data and a process for quick response to environmental changes. The use of information services to support tracking systems, process improvement teams, Hoshin planning, daily control/process management, simulation modeling, and a continuous operational assessment and response (COAR) system has been an integral part of the TQM effort at Bethesda Hospital.

  16. Experience with nuclear medicine information system.

    PubMed

    Volkan-Salanci, Bilge; Sahin, Figen; Babekoğlu, Vahide; Uğur, Omer

    2012-12-01

    Radiology information system (RIS) is basically evolved for the need of radiologists and ignores the vital steps needed for a proper work flow of Nuclear Medicine Department. Moreover, CT/MRI oriented classical PACS systems are far from satisfying Nuclear Physicians like storing dynamic data for reprocessing and quantitative analysis of colored images. Our purpose was to develop a workflow based Nuclear Medicine Information System (NMIS) that fulfills the needs of Nuclear Medicine Department and its integration to hospital PACS system. Workflow in NMIS uses HL7 (health level seven) and steps include, patient scheduling and retrieving information from HIS (hospital information system), radiopharmacy, acquisition, digital reporting and approval of the reports using Nuclear Medicine specific diagnostic codes. Images and dynamic data from cameras of are sent to and retrieved from PACS system (Corttex©) for reprocessing and quantitative analysis. NMIS has additional functions to the RIS such as radiopharmaceutical management program which includes stock recording of both radioactive and non-radioactive substances, calculation of the radiopharmaceutical dose for individual patient according to body weight and maximum permissible activity, and calculation of radioactivity left per unit volume for each radionuclide according their half lives. Patient scheduling and gamma camera patient work list settings were arranged according to specific Nuclear Medicine procedures. Nuclear Medicine images and reports can be retrieved and viewed from HIS. NMIS provides functionality to standard RIS and PACS system according to the needs of Nuclear Medicine. None declared.

  17. EOSDIS Science Data Information and Analysis Systems

    NASA Astrophysics Data System (ADS)

    Behnke, J.; Ullman, R.; Pfister, R.

    2002-12-01

    NASA's Earth Science Data Information Systems (ESDIS) Project is committed to operating and maintaining a quality Earth Observing System (EOS) Data and Information System (EOSDIS) which enables research by Earth scientists and fosters data accessibility and application by the broader user community. With the recent launch of Aqua, a few hundred new datasets will be added to the current 1560 datasets available through EOSDIS. One of the core functions at ESDIS is to enable the processing of all science data collected from the various EOS missions including Terra and Aqua, upcoming ICESat and Aura and other missions. There are many EOS Science data producers, data users, planners and managers of available data systems and tools for managing EOS data. There are also many services available through EOSDIS including those that will help scientists process, archive and access data and information for research, applications, planning and management. This paper will describe system services, functionality, access requirements and procedures and the intended user community that work principally with EOSDIS data. It will address analysis tools, data population tools, specific EOSDIS data sets and metadata types, tools for metadata creation and management, tools for distribution, EOSDIS data formats and distribution techniques. New techniques are critical to the success of EOS data manipulation including data mining, intelligent data archiving, data fusion, agent technologies, visualization, and other advanced information system concepts. Data management is key to EOSDIS and our strategic focus areas look to EOSDIS evolution, external integration, data system development and relationship building with our user community.

  18. Embedded ubiquitous services on hospital information systems.

    PubMed

    Kuroda, Tomohiro; Sasaki, Hiroshi; Suenaga, Takatoshi; Masuda, Yasushi; Yasumuro, Yoshihiro; Hori, Kenta; Ohboshi, Naoki; Takemura, Tadamasa; Chihara, Kunihiro; Yoshihara, Hiroyuki

    2012-11-01

    A Hospital Information Systems (HIS) have turned a hospital into a gigantic computer with huge computational power, huge storage and wired/wireless local area network. On the other hand, a modern medical device, such as echograph, is a computer system with several functional units connected by an internal network named a bus. Therefore, we can embed such a medical device into the HIS by simply replacing the bus with the local area network. This paper designed and developed two embedded systems, a ubiquitous echograph system and a networked digital camera. Evaluations of the developed systems clearly show that the proposed approach, embedding existing clinical systems into HIS, drastically changes productivity in the clinical field. Once a clinical system becomes a pluggable unit for a gigantic computer system, HIS, the combination of multiple embedded systems with application software designed under deep consideration about clinical processes may lead to the emergence of disruptive innovation in the clinical field.

  19. Why All the Fuss about Information Systems? or Information Systems as Golden Anchors in Higher Education

    ERIC Educational Resources Information Center

    Gorr, William; Hossler, Don

    2006-01-01

    The importance and attention given to information systems are relatively new phenomena in the history of higher education. This chapter documents the ascendancy of information systems in the scheme of institutional priorities and considers the strengths and weaknesses associated with vended and homegrown systems.

  20. Computer Information System For Nuclear Medicine

    NASA Astrophysics Data System (ADS)

    Cahill, P. T.; Knowles, R. J.....; Tsen, O.

    1983-12-01

    To meet the complex needs of a nuclear medicine division serving a 1100-bed hospital, a computer information system has been developed in sequential phases. This database management system is based on a time-shared minicomputer linked to a broadband communications network. The database contains information on patient histories, billing, types of procedures, doses of radiopharmaceuticals, times of study, scanning equipment used, and technician performing the procedure. These patient records are cycled through three levels of storage: (a) an active file of 100 studies for those patients currently scheduled, (b) a temporary storage level of 1000 studies, and (c) an archival level of 10,000 studies containing selected information. Merging of this information with reports and various statistical analyses are possible. This first phase has been in operation for well over a year. The second phase is an upgrade of the size of the various storage levels by a factor of ten.