Sample records for initial construction cost

  1. 18 CFR 4.1 - Initial cost statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OF PROJECT COSTS Determination of Cost of Projects Constructed Under License § 4.1 Initial cost statement. (a) Notification of Commission. When a project is constructed under a license issued under the... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Initial cost statement...

  2. 18 CFR 4.1 - Initial cost statement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF PROJECT COSTS Determination of Cost of Projects Constructed Under License § 4.1 Initial cost statement. (a) Notification of Commission. When a project is constructed under a license issued under the... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Initial cost statement...

  3. 18 CFR 4.1 - Initial cost statement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF PROJECT COSTS Determination of Cost of Projects Constructed Under License § 4.1 Initial cost statement. (a) Notification of Commission. When a project is constructed under a license issued under the... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Initial cost statement...

  4. 18 CFR 4.1 - Initial cost statement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF PROJECT COSTS Determination of Cost of Projects Constructed Under License § 4.1 Initial cost statement. (a) Notification of Commission. When a project is constructed under a license issued under the... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Initial cost statement...

  5. House Construction: How To Reduce Costs

    Treesearch

    Jerry O. Newman; Norman C. Teter; Constance D. O' Brien

    1969-01-01

    You're building a house and want to keep down the cost. How can you do it? First, plan carefully "on paper" before you start construction. By doing so, you can avoid costly mistakesinthebuildingandinthe purchase of materials. Careful planning and proper design will reduce not only the initial cost but also the cost of furnishings, utilities, and...

  6. Optimal transfers between unstable periodic orbits using invariant manifolds

    NASA Astrophysics Data System (ADS)

    Davis, Kathryn E.; Anderson, Rodney L.; Scheeres, Daniel J.; Born, George H.

    2011-03-01

    This paper presents a method to construct optimal transfers between unstable periodic orbits of differing energies using invariant manifolds. The transfers constructed in this method asymptotically depart the initial orbit on a trajectory contained within the unstable manifold of the initial orbit and later, asymptotically arrive at the final orbit on a trajectory contained within the stable manifold of the final orbit. Primer vector theory is applied to a transfer to determine the optimal maneuvers required to create the bridging trajectory that connects the unstable and stable manifold trajectories. Transfers are constructed between unstable periodic orbits in the Sun-Earth, Earth-Moon, and Jupiter-Europa three-body systems. Multiple solutions are found between the same initial and final orbits, where certain solutions retrace interior portions of the trajectory. All transfers created satisfy the conditions for optimality. The costs of transfers constructed using manifolds are compared to the costs of transfers constructed without the use of manifolds. In all cases, the total cost of the transfer is significantly lower when invariant manifolds are used in the transfer construction. In many cases, the transfers that employ invariant manifolds are three times more efficient, in terms of fuel expenditure, than the transfer that do not. The decrease in transfer cost is accompanied by an increase in transfer time of flight.

  7. Formation of costs of high-rise objects of housing and civil purpose based on enlarged norms

    NASA Astrophysics Data System (ADS)

    Vorotyntseva, Anna; Ovsiannikov, Andrei; Bolgov, Vladimir

    2018-03-01

    When determining the cost of capital construction objects, for purposes of pre-design workings out and purposes of initial maximum initial price determination on tenders, construction price norms are used (CPNs). Modern CPNs are not designed to determine the value of high-rise buildings. It is necessary to adapt modern CPNs to get opportunity for the possibility to take into account special cost factors in determining the cost of high-rise buildings. The main ways can be: selection of new representative objects or application of additional correction factors.

  8. 18 CFR 4.20 - Initial statement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.20 Initial statement. (a) Notification of Commission. In all cases where licenses are issued for projects... letter shall also include a statement to the effect that actual legitimate original cost, or if not known...

  9. 18 CFR 4.20 - Initial statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.20 Initial statement. (a) Notification of Commission. In all cases where licenses are issued for projects... letter shall also include a statement to the effect that actual legitimate original cost, or if not known...

  10. 18 CFR 4.20 - Initial statement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.20 Initial statement. (a) Notification of Commission. In all cases where licenses are issued for projects... letter shall also include a statement to the effect that actual legitimate original cost, or if not known...

  11. 18 CFR 4.20 - Initial statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.20 Initial statement. (a) Notification of Commission. In all cases where licenses are issued for projects... letter shall also include a statement to the effect that actual legitimate original cost, or if not known...

  12. 18 CFR 4.20 - Initial statement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.20 Initial statement. (a) Notification of Commission. In all cases where licenses are issued for projects... letter shall also include a statement to the effect that actual legitimate original cost, or if not known...

  13. Prevention of Roller Bearing-Initiated Burnoffs in Railroad Freight Car Journals

    DOT National Transportation Integrated Search

    1979-01-01

    The objective of this program was to determine the technical feasibility and cost effectiveness of constructing three separate devices for the prevention of catastrophic roller bearing-initiated, railroad journal failure. 1. Construction of a low cos...

  14. User costs as one of main advantages of precast concrete application in highway construction

    NASA Astrophysics Data System (ADS)

    Tomek, Radan

    2017-09-01

    Road user cost primarily refer to the monetized components of road (re)construction impacts, such as the user delay costs, vehicle operating costs, crash costs and emission costs. Objective of this paper is to analyze and appraise the advantages and benefits of the innovative prefabrication approach in contrast to traditional cast-in-place construction method. The goal is to reduce these additional costs borne by motorists and the community at-large as a result of road construction activity to their minimum through application of the prefabrication. Assessing two basic possible approaches to highway infrastructure construction - casting the road pavements and structures either in place or precast off the site - it can be concluded that the initial capital investment costs do not vary much. Substantial differences can be recognized when comparing their life-cycle costs and an extent to which their construction process affects the public, environment and the local economy. Prefabrication of any structure component off-site offers major construction time and user cost savings in comparison with the traditional cast-in-place methods of construction. Precast prestressed road pavements’ technology and precasting bridges’ parts and elements offers dramatic increase in durability, while it also substantially decreases construction time and resulting user costs.

  15. 42 CFR 137.302 - Are Federal funds available to cover start-up costs associated with initial Tribal assumption of...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... associated with initial Tribal assumption of environmental responsibilities? 137.302 Section 137.302 Public... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Nepa Process § 137.302 Are Federal funds available to cover start-up costs associated with initial Tribal assumption of environmental...

  16. 42 CFR 137.302 - Are Federal funds available to cover start-up costs associated with initial Tribal assumption of...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... associated with initial Tribal assumption of environmental responsibilities? 137.302 Section 137.302 Public... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Nepa Process § 137.302 Are Federal funds available to cover start-up costs associated with initial Tribal assumption of environmental...

  17. Construction Performance Optimization toward Green Building Premium Cost Based on Greenship Rating Tools Assessment with Value Engineering Method

    NASA Astrophysics Data System (ADS)

    Latief, Yusuf; Berawi, Mohammed Ali; Basten, Van; Riswanto; Budiman, Rachmat

    2017-07-01

    Green building concept becomes important in current building life cycle to mitigate environment issues. The purpose of this paper is to optimize building construction performance towards green building premium cost, achieving green building rating tools with optimizing life cycle cost. Therefore, this study helps building stakeholder determining building fixture to achieve green building certification target. Empirically the paper collects data of green building in the Indonesian construction industry such as green building fixture, initial cost, operational and maintenance cost, and certification score achievement. After that, using value engineering method optimized green building fixture based on building function and cost aspects. Findings indicate that construction performance optimization affected green building achievement with increasing energy and water efficiency factors and life cycle cost effectively especially chosen green building fixture.

  18. Cost Control

    ERIC Educational Resources Information Center

    Foreman, Phillip

    2009-01-01

    Education administrators involved in construction initiatives unanimously agree that when it comes to change orders, less is more. Change orders have a negative rippling effect of driving up building costs and producing expensive project delays that often interfere with school operations and schedules. Some change orders are initiated by schools…

  19. Metal Building Systems Fit To Be Tried

    ERIC Educational Resources Information Center

    Nation's Schools, 1974

    1974-01-01

    Describes the advantages of metal building systems in school construction. These advantages include faster occupancy, lower initial costs, reduced maintenance, flexibility, and predictability of cost. (Author/DN)

  20. Cost Analysis of Leed Certified United States Navy Buildings

    DTIC Science & Technology

    2011-08-03

    be accumulated in order to offset initial investment costs - St = Savings in operational costs in year t associated with a given alternative - ∆I0...ior Non-Structural Elements er.o• 2 1 Construction Waste ManagenMnt Oivort 50% fro m Disposal Crocllt 22 Construction Waste Managemen t , Divert 75... Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202- 4302. Respondents should be aware that notwithstanding

  1. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... costs incurred before initiation of project construction. An applicant may make no subsequent claim for... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Summary of construction grant program... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act...

  2. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... costs incurred before initiation of project construction. An applicant may make no subsequent claim for... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Summary of construction grant program... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act...

  3. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... costs incurred before initiation of project construction. An applicant may make no subsequent claim for... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Summary of construction grant program... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act...

  4. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... costs incurred before initiation of project construction. An applicant may make no subsequent claim for... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Summary of construction grant program... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act...

  5. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... costs incurred before initiation of project construction. An applicant may make no subsequent claim for... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Summary of construction grant program... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act...

  6. 24 CFR 891.745 - Replacement reserve.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... section, total structures include main buildings, accessory buildings, garages, and other buildings. The... cost of the total structures (for new construction projects), 0.4 percent of the cost of the initial...

  7. 24 CFR 891.745 - Replacement reserve.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... section, total structures include main buildings, accessory buildings, garages, and other buildings. The... cost of the total structures (for new construction projects), 0.4 percent of the cost of the initial...

  8. 24 CFR 891.745 - Replacement reserve.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... section, total structures include main buildings, accessory buildings, garages, and other buildings. The... cost of the total structures (for new construction projects), 0.4 percent of the cost of the initial...

  9. 24 CFR 891.745 - Replacement reserve.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... section, total structures include main buildings, accessory buildings, garages, and other buildings. The... cost of the total structures (for new construction projects), 0.4 percent of the cost of the initial...

  10. 24 CFR 891.745 - Replacement reserve.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... section, total structures include main buildings, accessory buildings, garages, and other buildings. The... cost of the total structures (for new construction projects), 0.4 percent of the cost of the initial...

  11. Tips on preventing or minimizing construction claims.

    PubMed

    Kasimer, J H

    1981-02-01

    With proper planning and use of successful techniques of claims avoidance, recognition, and resolution from the initial stages of the project, a hospital can prevent or minimize construction delays and claims and can complete its new construction in a reasonable atmosphere with a minimum of cost.

  12. Maglev guideway cost and construction schedule assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plotkin, D.; Kim, S.

    1997-05-01

    A summary of construction cost and scheduling information is presented for four maglev guideway designs on an example route from Baltimore, MD to Newark, NJ. This work results from the National Maglev Initiative (NMI), a government-industry effort from 1989 to 1994. The system design concepts used as a basis for developing cost and construction scheduling information, were submitted by four industry consortia solely for this analysis, and represent their own unpublished designs. The detailed cost and construction schedule analyses cover the main guideway only. A summary estimate was made for stations, power distribution systems, maintenance facilities, and other types ofmore » infrastructure. The results of the analyses indicate a number of design aspects which must receive further consideration by future designers. These aspects will affect the practical and economic construction and long-term maintenance of a high-speed maglev guideway.« less

  13. Second generation precast deck panel (NUDECK) system.

    DOT National Transportation Integrated Search

    2010-12-01

    The majority of today's bridge decks are built using cast-in-place concrete construction. This is due to the perceived : low initial cost and constructor familiarity with the system. This research report describes the design, details, and : construct...

  14. Determinants of escalating costs in low risk workers' compensation claims.

    PubMed

    Bernacki, Edward J; Yuspeh, Larry; Tao, Xuguang

    2007-07-01

    To identify and quantify attributes that lead to unanticipated cost escalation in workers' compensation claims. We constructed four claim categories: low initial reserve/low cost, migrated catastrophic (low initial reserve/high cost), high initial reserve/low cost, and catastrophic (high initial reserve/high cost). To assess the attributes associated with the increased cost of migrated catastrophic claims, we analyzed 36,329 Louisiana workers' compensation claims in the four categories over a 5-year period. In the 729 claims initially thought to be low-cost claims (migrated catastrophic), the most significant predictors for cost escalation were attorney involvement and claim duration, followed by low back disorder, married/single/divorced status, male gender, small company size, high premium, reporting delays, and older age. These injuries accounted for 2% of all claims but 32.3% of the costs. Accelerated escalation of costs occurred late in the claim cycle (2 years). Certain attributes, particularly attorney involvement and claim duration, are associated with unanticipated cost escalation in a small number of claims that drastically affect overall losses. The results of this study suggest that these cases may be identified and addressed before rapid escalation occurs.

  15. NREL: News - New Design Tool Analyzes Cost of Operating a Building Over its

    Science.gov Websites

    Lifetime Analyzes Cost of Operating a Building Over its Lifetime Golden, Colo., August 2, 2002 taking into consideration such factors as the initial cost of construction, mortgage payments, annual supply their own cost estimates. "Energy-10 allows the user to play 'what if' games while designing

  16. A Cost-Minimization Analysis of Tissue-Engineered Constructs for Corneal Endothelial Transplantation

    PubMed Central

    Tan, Tien-En; Peh, Gary S. L.; George, Benjamin L.; Cajucom-Uy, Howard Y.; Dong, Di; Finkelstein, Eric A.; Mehta, Jodhbir S.

    2014-01-01

    Corneal endothelial transplantation or endothelial keratoplasty has become the preferred choice of transplantation for patients with corneal blindness due to endothelial dysfunction. Currently, there is a worldwide shortage of transplantable tissue, and demand is expected to increase further with aging populations. Tissue-engineered alternatives are being developed, and are likely to be available soon. However, the cost of these constructs may impair their widespread use. A cost-minimization analysis comparing tissue-engineered constructs to donor tissue procured from eye banks for endothelial keratoplasty was performed. Both initial investment costs and recurring costs were considered in the analysis to arrive at a final tissue cost per transplant. The clinical outcomes of endothelial keratoplasty with tissue-engineered constructs and with donor tissue procured from eye banks were assumed to be equivalent. One-way and probabilistic sensitivity analyses were performed to simulate various possible scenarios, and to determine the robustness of the results. A tissue engineering strategy was cheaper in both investment cost and recurring cost. Tissue-engineered constructs for endothelial keratoplasty could be produced at a cost of US$880 per transplant. In contrast, utilizing donor tissue procured from eye banks for endothelial keratoplasty required US$3,710 per transplant. Sensitivity analyses performed further support the results of this cost-minimization analysis across a wide range of possible scenarios. The use of tissue-engineered constructs for endothelial keratoplasty could potentially increase the supply of transplantable tissue and bring the costs of corneal endothelial transplantation down, making this intervention accessible to a larger group of patients. Tissue-engineering strategies for corneal epithelial constructs or other tissue types, such as pancreatic islet cells, should also be subject to similar pharmacoeconomic analyses. PMID:24949869

  17. A cost-minimization analysis of tissue-engineered constructs for corneal endothelial transplantation.

    PubMed

    Tan, Tien-En; Peh, Gary S L; George, Benjamin L; Cajucom-Uy, Howard Y; Dong, Di; Finkelstein, Eric A; Mehta, Jodhbir S

    2014-01-01

    Corneal endothelial transplantation or endothelial keratoplasty has become the preferred choice of transplantation for patients with corneal blindness due to endothelial dysfunction. Currently, there is a worldwide shortage of transplantable tissue, and demand is expected to increase further with aging populations. Tissue-engineered alternatives are being developed, and are likely to be available soon. However, the cost of these constructs may impair their widespread use. A cost-minimization analysis comparing tissue-engineered constructs to donor tissue procured from eye banks for endothelial keratoplasty was performed. Both initial investment costs and recurring costs were considered in the analysis to arrive at a final tissue cost per transplant. The clinical outcomes of endothelial keratoplasty with tissue-engineered constructs and with donor tissue procured from eye banks were assumed to be equivalent. One-way and probabilistic sensitivity analyses were performed to simulate various possible scenarios, and to determine the robustness of the results. A tissue engineering strategy was cheaper in both investment cost and recurring cost. Tissue-engineered constructs for endothelial keratoplasty could be produced at a cost of US$880 per transplant. In contrast, utilizing donor tissue procured from eye banks for endothelial keratoplasty required US$3,710 per transplant. Sensitivity analyses performed further support the results of this cost-minimization analysis across a wide range of possible scenarios. The use of tissue-engineered constructs for endothelial keratoplasty could potentially increase the supply of transplantable tissue and bring the costs of corneal endothelial transplantation down, making this intervention accessible to a larger group of patients. Tissue-engineering strategies for corneal epithelial constructs or other tissue types, such as pancreatic islet cells, should also be subject to similar pharmacoeconomic analyses.

  18. An economic analysis of alternative paving materials

    NASA Astrophysics Data System (ADS)

    Mustain, J. L.

    1982-12-01

    The purpose of this paper is to present a means for economic analysis of alternative equivalent pavement designs, considering such factors as initial construction cost, annual maintenance cost, salvage value and the various intangibles which occur during the analysis period. Having established a means of economic comparison, it is then the intent of this paper to show that Portland Cement Concrete has been and is a viable pavement alternative and ought to receive due consideration in the military construction program.

  19. A New Model for Solving Time-Cost-Quality Trade-Off Problems in Construction

    PubMed Central

    Fu, Fang; Zhang, Tao

    2016-01-01

    A poor quality affects project makespan and its total costs negatively, but it can be recovered by repair works during construction. We construct a new non-linear programming model based on the classic multi-mode resource constrained project scheduling problem considering repair works. In order to obtain satisfactory quality without a high increase of project cost, the objective is to minimize total quality cost which consists of the prevention cost and failure cost according to Quality-Cost Analysis. A binary dependent normal distribution function is adopted to describe the activity quality; Cumulative quality is defined to determine whether to initiate repair works, according to the different relationships among activity qualities, namely, the coordinative and precedence relationship. Furthermore, a shuffled frog-leaping algorithm is developed to solve this discrete trade-off problem based on an adaptive serial schedule generation scheme and adjusted activity list. In the program of the algorithm, the frog-leaping progress combines the crossover operator of genetic algorithm and a permutation-based local search. Finally, an example of a construction project for a framed railway overpass is provided to examine the algorithm performance, and it assist in decision making to search for the appropriate makespan and quality threshold with minimal cost. PMID:27911939

  20. Percutaneous Trigger Finger Release: A Cost-effectiveness Analysis.

    PubMed

    Gancarczyk, Stephanie M; Jang, Eugene S; Swart, Eric P; Makhni, Eric C; Kadiyala, Rajendra Kumar

    2016-07-01

    Percutaneous trigger finger releases (TFRs) performed in the office setting are becoming more prevalent. This study compares the costs of in-hospital open TFRs, open TFRs performed in ambulatory surgical centers (ASCs), and in-office percutaneous releases. An expected-value decision-analysis model was constructed from the payer perspective to estimate total costs of the three competing treatment strategies for TFR. Model parameters were estimated based on the best available literature and were tested using multiway sensitivity analysis. Percutaneous TFR performed in the office and then, if needed, revised open TFR performed in the ASC, was the most cost-effective strategy, with an attributed cost of $603. The cost associated with an initial open TFR performed in the ASC was approximately 7% higher. Initial open TFR performed in the hospital was the least cost-effective, with an attributed cost nearly twice that of primary percutaneous TFR. An initial attempt at percutaneous TFR is more cost-effective than an open TFR. Currently, only about 5% of TFRs are performed in the office; therefore, a substantial opportunity exists for cost savings in the future. Decision model level II.

  1. Evaluation of performance and cost-effectiveness of thin pavement surface treatments : progress report #1.

    DOT National Transportation Integrated Search

    1987-03-01

    This is the initial report for a study to determine the long term performance and life cycle costs for thin surface treatments. For this study a thin surface treatment is defined as less than 2 inches. A total of 89 projects constructed during 1984, ...

  2. Life Cycle Cost Analysis Handbook. First Edition.

    ERIC Educational Resources Information Center

    Alaska State Dept. of Education and Early Development, Juneau.

    This handbook presents guidelines on the Life Cycle Cost Analysis (LCCA) of building operations over the life of a building to assist school districts and consultants with evaluating proposed educational facility construction projects. It defines the terminology found in an LCCA, such as initial and future expenses, residual value, real discount…

  3. Investigation of test methods, material properties, and processes for solar cell encapsulants. Encapsulation task of the low-cost silicon solar array project

    NASA Technical Reports Server (NTRS)

    1977-01-01

    During this quarter, flat-plate solar collector systems were considered and six basic construction elements were identified: outer coatings, superstrates, pottants, substrates, undercoats, and adhesives. Materials surveys were then initiated to discover either generic classes or/and specific products to function as each construction element. Cost data included in the surveys permit ready evaluation of each material. Silicones, fluorocarbons, glass, and acrylic polymers have the highest inherent weatherability of materials studied to date. Only acrylics, however, combine low costs, environmental resistance, and potential processability. This class will receive particular emphasis.

  4. Antiretroviral drug costs and prescription patterns in British Columbia, Canada: 1996-2011.

    PubMed

    Nosyk, Bohdan; Montaner, Julio S G; Yip, Benita; Lima, Viviane D; Hogg, Robert S

    2014-04-01

    Treatment options and therapeutic guidelines have evolved substantially since highly active antiretroviral treatment (HAART) became the standard of HIV care in 1996. We conducted the present population-based analysis to characterize the determinants of direct costs of HAART over time in British Columbia, Canada. We considered individuals ever receiving HAART in British Columbia from 1996 to 2011. Linear mixed-effects regression models were constructed to determine the effects of demographic indicators, clinical stage, and treatment characteristics on quarterly costs of HAART (in 2010$CDN) among individuals initiating in different temporal periods. The least-square mean values were estimated by CD4 category and over time for each temporal cohort. Longitudinal data on HAART recipients (N = 9601, 17.6% female, mean age at initiation = 40.5) were analyzed. Multiple regression analyses identified demographics, treatment adherence, and pharmacological class to be independently associated with quarterly HAART costs. Higher CD4 cell counts were associated with modestly lower costs among pre-HAART initiators [least-square means (95% confidence interval), CD4 > 500: 4674 (4632-4716); CD4: 350-499: 4765 (4721-4809) CD4: 200-349: 4826 (4780-4871); CD4 <200: 4809 (4759-4859)]; however these differences were not significant among post-2003 HAART initiators. Population-level mean costs increased through 2006 and stabilized post-2003 HAART initiators incurred quarterly costs up to 23% lower than pre-2000 HAART initiators in 2010. Our results highlight the magnitude of the temporal changes in HAART costs, and disparities between recent and pre-HAART initiators. This methodology can improve the precision of economic modeling efforts by using detailed cost functions for annual, population-level medication costs according to the distribution of clients by clinical stage and era of treatment initiation.

  5. Using space resources

    NASA Technical Reports Server (NTRS)

    Sullivan, Thomas A.; Mckay, David S.

    1991-01-01

    The topics covered include the following: reducing the cost of space exploration; the high cost of shipping; lunar raw materials; some useful space products; energy from the moon; ceramic, glass, and concrete construction materials; mars atmosphere resources; relationship to the Space Exploration Initiative (SEI); an evolutionary approach to using space resources; technology development; and oxygen and metal coproduction.

  6. Cost-effectiveness analysis of initial treatment strategies for mild-to-moderate Clostridium difficile infection in hospitalized patients.

    PubMed

    Ford, Diana C; Schroeder, Mary C; Ince, Dilek; Ernst, Erika J

    2018-06-14

    The cost-effectiveness of initial treatment strategies for mild-to-moderate Clostridium difficile infection (CDI) in hospitalized patients was evaluated. Decision-analytic models were constructed to compare initial treatment with metronidazole, vancomycin, and fidaxomicin. The primary model included 1 recurrence, and the secondary model included up to 3 recurrences. Model variables were extracted from published literature with costs based on a healthcare system perspective. The primary outcome was the incremental cost-effective ratio (ICER) between initial treatment strategies. In the primary model, the overall percentage of patients cured was 94.23%, 95.19%, and 96.53% with metronidazole, vancomycin, and fidaxomicin, respectively. Expected costs per case were $1,553.01, $1,306.62, and $5,095.70, respectively. In both models, vancomycin was more effective and less costly than metronidazole, resulting in negative ICERs. The ICERs for fidaxomicin compared with those for metronidazole and vancomycin in the primary model were $1,540.23 and $2,828.69 per 1% gain in cure, respectively. Using these models, a hospital currently treating initial episodes of mild-to-moderate CDI with metronidazole could expect to save $246.39-$388.37 per case treated by using vancomycin for initial therapy. A decision-analytic model revealed vancomycin to be cost-effective, compared with metronidazole, for treatment of initial episodes of mild-to-moderate CDI in adult inpatients. From the hospital perspective, initial treatment with vancomycin resulted in a higher probability of cure and a lower probability of colectomy, recurrence, persistent recurrence, and cost per case treated, compared with metronidazole. Use of fidaxomicin was associated with an increased probability of cure compared with metronidazole and vancomycin, but at a substantially increased cost. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  7. When does it pay to invest in a patch? The evolution of intentional niche construction.

    PubMed

    Mohlenhoff, Kathryn A; Codding, Brian F

    2017-09-01

    Humans modify their environments in ways that significantly transform the earth's ecosystems. Recent research suggests that such niche-constructing behaviors are not passive human responses to environmental variation, but instead should be seen as active and intentional management of the environment. Although such research is useful in highlighting the interactive dynamics between humans and their natural world, the niche-construction framework, as currently applied, fails to explain why people would decide to modify their environments in the first place. To help resolve this problem, we use a model of technological intensification to analyze the cost-benefit trade-offs associated with niche construction as a form of patch investment. We use this model to assess the costs and benefits of three paradigmatic cases of intentional niche construction in Western North America: the application of fire in acorn groves, the manufacture of fishing weirs, and the adoption of maize agriculture. Intensification models predict that investing in patch modification (niche construction) only provides a net benefit when the amount of resources needed crosses a critical threshold that makes the initial investment worthwhile. From this, it follows that low-cost investments, such as burning in oak groves, should be quite common, while more costly investments, such as maize agriculture, should be less common and depend on the alternatives available in the local environment. We examine how patterns of mobility, risk management, territoriality, and private property also co-evolve with the costs and benefits of niche construction. This approach illustrates that explaining niche-constructing behavior requires understanding the economic trade-offs involved in patch investment. Integrating concepts from niche construction and technological intensification models within a behavioral ecological framework provides insights into the coevolution and active feedback between adaptive behaviors and environmental change across human history. © 2017 Wiley Periodicals, Inc.

  8. Development of an electronic manometer for intrapleural pressure monitoring.

    PubMed

    Krenke, Rafał; Guć, Maciej; Grabczak, Elżbieta Magdalena; Michnikowski, Marcin; Pałko, Krzysztof Jakub; Chazan, Ryszarda; Gólczewski, Tomasz

    2011-01-01

    Measurement of intrapleural pressure is useful during various pleural procedures. However, a pleural manometer is rarely available. The aim of this study was to (1) construct an electronic pleural manometer, (2) assess the accuracy of the measurements done with the new device, (3) calculate the costs of the manometer construction and (4) perform an initial evaluation of the device in a clinical setting. Only widely accessible elements were used to construct the device. A vascular pressure transducer was used to transform pressure into an electronic signal. Reliability of the measurements was evaluated in a laboratory setting in a prospective, single-blind manner by comparing the results with those measured by a water manometer. Functionality of the device was assessed during therapeutic thoracentesis. The cost of the new pleural manometer was calculated. We built a small, portable device which can precisely measure intrapleural pressure. The measurement results showed very high agreement with those registered with a water manometer (r = 0.999; p < 0.001). The initial evaluation of the electronic manometer during therapeutic thoracentesis showed it was easy to use. The total time needed for 6 measurements after withdrawal of different volumes of pleural fluid in 1 patient did not exceed 6 min. The total cost of the device was calculated to be <2,000 EUR. In the face of very limited offer of commercially available pleural manometers, it is possible to successfully construct a self-made, reliable, electronic pleural manometer at modest costs. The device is easy to use and enables data display and storage in the personal computer. Copyright © 2011 S. Karger AG, Basel.

  9. Injuries and illnesses from wood framing in residential construction, Washington State, 1993-1999.

    PubMed

    Shah, Syed Mahboob Ali; Bonauto, David; Silverstein, Barbara; Foley, Michael; Kalat, John

    2003-11-01

    The construction industry is associated with high rates of work-related injury. We used workers compensation data to describe the injuries and illnesses, claim rates, and claim costs associated with wood framing activities in construction. From 1993 to 1999, there were 33,021 accepted state fund workers compensation claims with direct costs of over $197 million. The average annual claim rate was 45 per 100 full-time equivalent. Statistically significant downward trends were noted in claim rates for all injuries and illnesses, compensable time loss claims, eye and fall injuries. However, these trends were not statistically significantly different from those observed in all other construction risk classes combined. The information in this report can be used to guide prevention efforts and to evaluate the effectiveness of Washington state initiatives to reduce injury and illness rates in wood frame construction.

  10. Alternative pavement designs : Randolph park and ride.

    DOT National Transportation Integrated Search

    2013-05-01

    Previous research on alternative pavement type bidding has proven that various treatments : are unique in terms of constructability, material characteristics, and associated performance. : While some treatments may have higher initial costs, it is im...

  11. Improving building performance using smart building concept: Benefit cost ratio comparison

    NASA Astrophysics Data System (ADS)

    Berawi, Mohammed Ali; Miraj, Perdana; Sayuti, Mustika Sari; Berawi, Abdur Rohim Boy

    2017-11-01

    Smart building concept is an implementation of technology developed in the construction industry throughout the world. However, the implementation of this concept is still below expectations due to various obstacles such as higher initial cost than a conventional concept and existing regulation siding with the lowest cost in the tender process. This research aims to develop intelligent building concept using value engineering approach to obtain added value regarding quality, efficiency, and innovation. The research combined quantitative and qualitative approach using questionnaire survey and value engineering method to achieve the research objectives. The research output will show additional functions regarding technology innovation that may increase the value of a building. This study shows that smart building concept requires higher initial cost, but produces lower operational and maintenance costs. Furthermore, it also confirms that benefit-cost ratio on the smart building was much higher than a conventional building, that is 1.99 to 0.88.

  12. Directions for lunar construction - A derivation of requirements from a construction scenario analysis

    NASA Technical Reports Server (NTRS)

    Dias, William S.; Matijevic, Jacob R.; Venkataraman, Subramani T.; Smith, Jeffrey H.; Lindemann, Randel A.; Levin, Richard R.

    1992-01-01

    This paper provides an initial trade-off study among several lunar construction options available to the Space Exploration Initiative. The relative time effectiveness of Extra-Vehicular Activity (EVA), Intra-Vehicular Activity (IVA), and Earth-based remote control assembly and construction methods are studied. Also considered is whether there is any construction time savings to building roads in advance, or surveying the construction sites with orbiters or rovers in advance. The study was conducted by adding detail to a potentially real scenario - a nuclear power plant - and applying time multipliers for the various control options and terrain alternatives, provided by roboticists among the authors. The authors conclude that IVA is a faster construction method than either EVA or construction conducted remotely from Earth. Surveying proposed sites in advance, with orbiters and rovers, provides a significant time savings through adding to certainty, and therefore may be cost effective. Developing a heavy-lift launch capability and minimizing assembly and construction processes by landing large payloads is probably worthwhile to the degree possible, as construction activities would use a large amount of surface operations time.

  13. Maglev System Concept Definition (SCD) System Safety Review

    DOT National Transportation Integrated Search

    1993-01-07

    As part of the National Maglev Initiative (NMI), the Federal Railroad : Administration (FRA) solicited proposals to conceptually define the technical feasibility, : performance and costs of constructing and operating Maglev systems in the United : St...

  14. Cost-effective solutions for sewage treatment in developing countries--the case of Brazil.

    PubMed

    Jordão, E P; Volschan, I

    2004-01-01

    Cost-effective solutions are a must in developing countries, not only regarding investment costs, but also in respect to technology and operating practices. With these two goals in mind, in Brazil a particular effort has been directed for the development and application of the Chemical Enhanced Primary Treatment (CEPT) process and of the Upflow Anaerobic Sludge Blanket (UASB) process, both followed by complementary secondary treatment. Both technologies are under current expansion in Brazil. Large CEPT plants have been designed and built, up to 3.7 m3/s average design flow, as well as large UASB reactors, up to 3.0 m3/s average design flow. The applied technologies are cost-effective: they present low investment and efficiencies of BOD removal of up to 50% to 70%. They allow the plant construction in steps, an initial phase with efficiency over the usual primary treatment, and in order to achieve best effluent quality and meet legal water quality standards, a logic upgrade post-treatment can later on be implemented. The higher initial reduction of BOD and TSS also permits savings in construction and operational costs of secondary treatment, due to lower organic load and lower energy consumption. Sludge represents a particular point of attention: in the cases when the CEPT was used, Chemical Stabilisation of the Sludge (CSS) has also been practiced, eliminating the high construction costs of the digesters, all the plant staying chemically operated. In the cases when the UASB is used preceding secondary treatment, sludge can easily return to the anaerobic vessel, the costly sludge digestion unit being avoided. UASB reactors have practically no equipment in the anaerobic vessel, no energy consumption, low sludge production, and when applied in hot climates as in Brazil, heating devices are not required. The Brazilian experience, some particular cases, special comments on design and different secondary treatment processes are presented in this paper, as a contribution to the discussion of cost and benefits, a prime point to be considered.

  15. Second generation precast deck panel (NUDECK) system.

    DOT National Transportation Integrated Search

    2010-12-01

    "The majority of todays bridge decks are built using cast-in-place concrete construction. This is due to the perceived : low initial cost and constructor familiarity with the system. This research report describes the design, details, and : constr...

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kenji Akagi; Masayuki Ishiwata; Kenji Araki

    In nuclear power plant construction, countless variety of parts, products, and jigs more than one million are treated under construction. Furthermore, strict traceability to the history of material, manufacturing, and installation is required for all products from the start to finish of the construction, which enforce much workforce and many costs at every project. In an addition, the operational efficiency improvement is absolutely essential for the effective construction to reduce the initial investment for construction. As one solution, RFID (Radio Frequent Identification) application technology, one of the fundamental technologies to realize a ubiquitous society, currently expands its functionality and generalmore » versatility at an accelerating pace in mass-production industry. Hitachi believes RFID technology can be useful of one of the key solutions for the issues in non-mass production industry as well. Under this situation, Hitachi initiated the development of next generation plant concept (ubiquitous plant construction technology) which utilizes information and RFID technologies. In this paper, our application plans of RFID technology to nuclear power is described. (authors)« less

  17. Prototype of a low cost multiparameter probe

    NASA Astrophysics Data System (ADS)

    Koski, K.; Schwingle, R.; Pullin, M.

    2010-12-01

    Commercial multi-parameter probes provide accurate, high-resolution temporal data collection of a variety of water quality parameters, but their cost (>5,000) prohibits more than a few sampling locations. We present a design and prototype for a low cost (<250) probe. The cost of the probe is ~5% of commercially available probes, allowing for data collection from ~20 times more sampling points in a field location. The probe is constructed from a single-board microcontroller, a commercially available temperature sensor, a conductivity sensor, and a fabricated optical rhodamine sensor. Using a secure digital (SD) memory card, the probe can record over a month of data at a user specified interval. Construction, calibration, field deployment and data retrieval can be accomplished by a skilled undergraduate. Initial deployment will take place as part of a tracer test in the Valles Caldera National Preserve in northern New Mexico. Future work includes: addition of commercial ion selective electrodes (pH, bromide, nitrate, and others); construction of optically based sensors (chlorophyll, dissolved oxygen, and others); wireless networking between the sensors; and reduction of biofouling.

  18. Maximizing the use of local materials in HMA surfaces.

    DOT National Transportation Integrated Search

    2012-04-01

    One approach to reducing initial construction costs is to maximize the use of locally available aggregates. The main concern with using : locally available carbonate aggregates, however, is that they tend to polish under traffic and provide inadequat...

  19. 24 CFR 200.53 - Initial operating funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... standards established by the Commissioner for: (a) Accruals for taxes, ground rates, mortgage insurance premiums, and property insurance premiums, during the course of construction; (b) Meeting the cost of... Endorsement Generally Applicable to Multifamily and Health Care Facility Mortgage Insurance Programs; and...

  20. 24 CFR 200.53 - Initial operating funds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... standards established by the Commissioner for: (a) Accruals for taxes, ground rates, mortgage insurance premiums, and property insurance premiums, during the course of construction; (b) Meeting the cost of... Endorsement Generally Applicable to Multifamily and Health Care Facility Mortgage Insurance Programs; and...

  1. Assessing Treatment Effects of Inhaled Corticosteroids on Medical Expenses and Exacerbations among COPD Patients: Longitudinal Analysis of Managed Care Claims

    PubMed Central

    Akazawa, Manabu; Stearns, Sally C; Biddle, Andrea K

    2008-01-01

    Objective To assess costs, effectiveness, and cost-effectiveness of inhaled corticosteroids (ICS) augmenting bronchodilator treatment for chronic obstructive pulmonary disease (COPD). Data Sources Claims between 1997 and 2005 from a large managed care database. Study Design Individual-level, fixed-effects regression models estimated the effects of initiating ICS on medical expenses and likelihood of severe exacerbation. Bootstrapping provided estimates of the incremental cost per severe exacerbation avoided. Data Extraction Methods COPD patients aged 40 or older with ≥15 months of continuous eligibility were identified. Monthly observations for 1 year before and up to 2 years following initiation of bronchodilators were constructed. Principal Findings ICS treatment reduced monthly risk of severe exacerbation by 25 percent. Total costs with ICS increased for 16 months, but declined thereafter. ICS use was cost saving 46 percent of the time, with an incremental cost-effectiveness ratio of $2,973 per exacerbation avoided; for patients ≥50 years old, ICS was cost saving 57 percent of time. Conclusions ICS treatment reduces exacerbations, with an increase in total costs initially for the full sample. Compared with younger patients with COPD, patients aged 50 or older have reduced costs and improved outcomes. The estimated cost per severe exacerbation avoided, however, may be high for either group because of uncertainty as reflected by the large standard errors of the parameter estimates. PMID:18671750

  2. Cost-effectiveness of competing strategies for management of recurrent Clostridium difficile infection: a decision analysis.

    PubMed

    Konijeti, Gauree G; Sauk, Jenny; Shrime, Mark G; Gupta, Meera; Ananthakrishnan, Ashwin N

    2014-06-01

    Clostridium difficile infection (CDI) is an important cause of morbidity and healthcare costs, and is characterized by high rates of disease recurrence. The cost-effectiveness of newer treatments for recurrent CDI has not been examined, yet would be important to inform clinical practice. The aim of this study was to analyze the cost effectiveness of competing strategies for recurrent CDI. We constructed a decision-analytic model comparing 4 treatment strategies for first-line treatment of recurrent CDI in a population with a median age of 65 years: metronidazole, vancomycin, fidaxomicin, and fecal microbiota transplant (FMT). We modeled up to 2 additional recurrences following the initial recurrence. We assumed FMT delivery via colonoscopy as our base case, but conducted sensitivity analyses based on different modes of delivery. Willingness-to-pay threshold was set at $50 000 per quality-adjusted life-year. At our base case estimates, initial treatment of recurrent CDI using FMT colonoscopy was the most cost-effective strategy, with an incremental cost-effectiveness ratio of $17 016 relative to oral vancomycin. Fidaxomicin and metronidazole were both dominated by FMT colonoscopy. On sensitivity analysis, FMT colonoscopy remained the most cost-effective strategy at cure rates >88.4% and CDI recurrence rates <14.9%. Fidaxomicin required a cost <$1359 to meet our cost-effectiveness threshold. In clinical settings where FMT is not available or applicable, the preferred strategy appears to be initial treatment with oral vancomycin. In this decision analysis examining treatment strategies for recurrent CDI, we demonstrate that FMT colonoscopy is the most cost-effective initial strategy for management of recurrent CDI.

  3. Trastuzumab in early stage breast cancer: a cost-effectiveness analysis for Belgium.

    PubMed

    Neyt, Mattias; Huybrechts, Michel; Hulstaert, Frank; Vrijens, France; Ramaekers, Dirk

    2008-08-01

    Although trastuzumab is traditionally used in metastatic breast cancer treatment, studies reported on the efficacy and safety of trastuzumab in adjuvant setting for the treatment of early stage breast cancer in HER2+ tumors. We estimated the cost-effectiveness and budget impact of reimbursing trastuzumab in this indication from a payer's perspective. We constructed a health economic model. Long-term consequences of preventing patients to progress to metastatic breast cancer and side effects such as congestive heart failure were taken into account. Uncertainty was handled applying probabilistic modeling and through probabilistic sensitivity analyses. In the HERA scenario, applying an arbitrary threshold of euro30000 per life-year gained, early stage breast cancer treatment with trastuzumab is cost-effective for 9 out of 15 analyzed subgroups (according to age and stage). In contrast, treatment according to the FinHer scenario is cost-effective in 14 subgroups. Furthermore, the FinHer regimen is most of the times cost saving with an average incremental cost of euro668, euro-1045, and euro-6869 for respectively stages I, II and III breast cancer patients whereas the HERA regimen is never cost saving due to the higher initial treatment costs. The model shows better cost-effectiveness for the 9-week initial treatment (FinHer) compared to no trastuzumab treatment than for the 1-year post-chemotherapy treatment (HERA). Both from a medical and an economic point of view, the 9-week initial treatment regimen with trastuzumab shows promising results and justifies the initiation of a large comparative trial with a 1-year regimen.

  4. LSA silicon material task closed-cycle process development

    NASA Technical Reports Server (NTRS)

    Roques, R. A.; Wakefield, G. F.; Blocher, J. M., Jr.; Browning, M. F.; Wilson, W.

    1979-01-01

    The initial effort on feasibility of the closed cycle process was begun with the design of the two major items of untested equipment, the silicon tetrachloride by product converter and the rotary drum reactor for deposition of silicon from trichlorosilane. The design criteria of the initial laboratory equipment included consideration of the reaction chemistry, thermodynamics, and other technical factors. Design and construction of the laboratory equipment was completed. Preliminary silicon tetrachloride conversion experiments confirmed the expected high yield of trichlorosilane, up to 98 percent of theoretical conversion. A preliminary solar-grade polysilicon cost estimate, including capital costs considered extremely conservative, of $6.91/kg supports the potential of this approach to achieve the cost goal. The closed cycle process appears to have a very likely potential to achieve LSA goals.

  5. Construction of Experimental Roofing.

    DTIC Science & Technology

    1981-11-01

    buildings at Fort Benning, GA; Fort Knox, KY; and Fort Lewis, WA. Sheets of EPDM synthetic rubber were installed on buildings at Forts Benning and Lewis...Contract and Unit Costs 14 5 Polyurethane Foam Roofing -- Initial Physical Properties 28 6 EPDM Sheet Rubber Roofing -- Initial Physical Properties 30 7...the new system. The system selected for Area A was an EPDM synthetic rubber manufactured by Carlisle Tire and Rubber Company. The contract specified

  6. Capital update factor: a new era approaches.

    PubMed

    Grimaldi, P L

    1993-02-01

    The Health Care Financing Administration (HCFA) has constructed a preliminary model of a new capital update method which is consistent with the framework being developed to refine the update method for PPS operating costs. HCFA's eventual goal is to develop a single update framework for operating and capital costs. Initial results suggest that adopting the new capital update method would reduce capital payments substantially, which might intensify creditor's concerns about extending loans to hospitals.

  7. Prioritizing prevention opportunities in the Washington State construction industry, 2003-2007.

    PubMed

    Schoonover, Todd; Bonauto, David; Silverstein, Barbara; Adams, Darrin; Clark, Randy

    2010-06-01

    This study compares construction industry groups in Washington State by injury severity and cost, and ranks industry groups according to potential for prevention. All Washington State workers' compensation compensable claims with date of injury between 2003 and 2007 were classified into North American Industrial Classification System (NAICS) industry groups. Claims were then aggregated by injury type and industry groups were ranked according to a prevention index (PI). The PI is the average of the rank orders of the claim count and the claim incidence rate. A lower PI indicates a higher need for prevention activities. The severity rate was calculated as the number of days of time loss per 10,000 full-time equivalents (FTEs). For all injury types, construction industry groups occupy 7 of the top 15 PI ranks in Washington State. The severity rate among construction industry groups was twice that for non-construction groups for all injury types. Foundation, structure, and building exterior contractors (NAICS 2381) ranked highest in prevention potential and severity among construction industry groups for most common injury types including falls from elevation, fall on same level, struck by/against, and musculo-skeletal disorders of the neck, back, and upper extremity (WMSDs). Median claim costs by injury type were generally higher among construction industry groups. The construction industry in Washington State has a high severity rate and potential for prevention. The methods used for characterizing these industry groups can be adapted for comparison within and between other industries and states. These data can be used by industry groups and employers to identify higher cost and higher severity injury types. Knowledge about the relative frequencies and costs associated with different injury types will help employers and construction industry associations make better informed decisions about where prevention efforts are most needed and may have the greatest impact. The results of this study can also be used by industry stakeholders to cooperatively focus on high cost and high severity injuries and explore best practices, interventions, and solutions as demonstrated by efforts to prevent musculoskeletal disorders in masonry (Entzel, Albers, & Welch, 2007). Initiating construction industry groups to focus on high cost and high severity injuries may also help prevent other types of injuries. (c) 2010 National Safety Council. Published by Elsevier Ltd. All rights reserved.

  8. [Analysis of costs and cost-effectiveness of preferred GESIDA/National AIDS Plan regimens for initial antiretroviral therapy in human immunodeficiency virus infected adult patients in 2013].

    PubMed

    Blasco, Antonio Javier; Llibre, Josep M; Arribas, José Ramón; Boix, Vicente; Clotet, Bonaventura; Domingo, Pere; González-García, Juan; Knobel, Hernando; López, Juan Carlos; Lozano, Fernando; Miró, José M; Podzamczer, Daniel; Santamaría, Juan Miguel; Tuset, Montserrat; Zamora, Laura; Lázaro, Pablo; Gatell, Josep M

    2013-11-01

    The GESIDA and National AIDS Plan panel of experts have proposed "preferred regimens" of antiretroviral treatment (ART) as initial therapy in HIV infected patients for 2013. The objective of this study is to evaluate the costs and effectiveness of initiating treatment with these "preferred regimens". An economic assessment of costs and effectiveness (cost/effectiveness) was performed using decision tree analysis models. Effectiveness was defined as the probability of having viral load <50copies/mL at week48, in an intention-to-treat analysis. Cost of initiating treatment with an ART regime was defined as the costs of ART and its consequences (adverse effects, changes of ART regime and drug resistance analyses) during the first 48weeks. The perspective of the analysis is that of the National Health System was applied, only taking into account differential direct costs: ART (official prices), management of adverse effects, resistance studies, and determination of HLA B*5701. The setting is Spain and the costs are those of 2013. A sensitivity deterministic analysis was performed, constructing three scenarios for each regimen: baseline, most favourable, and most unfavourable cases. In the baseline case scenario, the cost of initiating treatment ranges from 6,747euros for TDF/FTC+NVP to 12,059euros for TDF/FTC+RAL. The effectiveness ranges between 0.66 for ABC/3TC+LPV/r and ABC/3TC+ATV/r, and 0.87 for TDF/FTC+RAL and ABC/3TC+RAL. Effectiveness, in terms of cost/effectiveness, varies between 8,396euros and 13,930euros per responder at 48weeks, for TDF/FTC/RPV and TDF/FTC+RAL, respectively. Taking ART at official prices, the most effective regimen was TDF/FTC/RPV, followed by the rest of non-nucleoside containing regimens. The sensitivity analysis confirms the robustness of these findings. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  9. Cost-effectiveness of Competing Strategies for Management of Recurrent Clostridium difficile Infection: A Decision Analysis

    PubMed Central

    Konijeti, Gauree G.; Sauk, Jenny; Shrime, Mark G.; Gupta, Meera; Ananthakrishnan, Ashwin N.

    2014-01-01

    Background. Clostridium difficile infection (CDI) is an important cause of morbidity and healthcare costs, and is characterized by high rates of disease recurrence. The cost-effectiveness of newer treatments for recurrent CDI has not been examined, yet would be important to inform clinical practice. The aim of this study was to analyze the cost effectiveness of competing strategies for recurrent CDI. Methods. We constructed a decision-analytic model comparing 4 treatment strategies for first-line treatment of recurrent CDI in a population with a median age of 65 years: metronidazole, vancomycin, fidaxomicin, and fecal microbiota transplant (FMT). We modeled up to 2 additional recurrences following the initial recurrence. We assumed FMT delivery via colonoscopy as our base case, but conducted sensitivity analyses based on different modes of delivery. Willingness-to-pay threshold was set at $50 000 per quality-adjusted life-year. Results. At our base case estimates, initial treatment of recurrent CDI using FMT colonoscopy was the most cost-effective strategy, with an incremental cost-effectiveness ratio of $17 016 relative to oral vancomycin. Fidaxomicin and metronidazole were both dominated by FMT colonoscopy. On sensitivity analysis, FMT colonoscopy remained the most cost-effective strategy at cure rates >88.4% and CDI recurrence rates <14.9%. Fidaxomicin required a cost <$1359 to meet our cost-effectiveness threshold. In clinical settings where FMT is not available or applicable, the preferred strategy appears to be initial treatment with oral vancomycin. Conclusions. In this decision analysis examining treatment strategies for recurrent CDI, we demonstrate that FMT colonoscopy is the most cost-effective initial strategy for management of recurrent CDI. PMID:24692533

  10. Best practices from WisDOT mega and ARRA projects--request for information : benchmarks and metrics.

    DOT National Transportation Integrated Search

    2012-03-01

    Successful highway construction is measured by cost, time, safety, and quality. One further measure of success is the quantity of Request for Information's (RFI) submitted and their impact. An RFI is a formal written procedure initiated by the contra...

  11. COST AND EFFECTIVENESS OF RADON RESISTANT FEATURES IN NEW SCHOOL BUILDINGS

    EPA Science Inventory

    The paper describes initial results of a study of several schools with radon resistant features that were recently constructed in the northeastern U. S. hese designs generally are based on experience with radon mitigation in existing houses and schools and radon- resistant new co...

  12. Eosinophilic esophagitis: dilate or medicate? A cost analysis model of the choice of initial therapy.

    PubMed

    Kavitt, R T; Penson, D F; Vaezi, M F

    2014-07-01

    Eosinophilic esophagitis (EoE) is an increasingly recognized clinical entity. The optimal initial treatment strategy in adults with EoE remains controversial. The aim of this study was to employ a decision analysis model to determine the less costly option between the two most commonly employed treatment strategies in EoE. We constructed a model for an index case of a patient with biopsy-proven EoE who continues to be symptomatic despite proton-pump inhibitor therapy. The following treatment strategies were included: (i) swallowed fluticasone inhaler (followed by esophagogastroduodenoscopy [EGD] with dilation if ineffective); and (ii) EGD with dilation (followed by swallowed fluticasone inhaler if ineffective). The time horizon was 1 year. The model focused on cost analysis of initial treatment strategies. The perspective of the healthcare payer was used. Sensitivity analyses were performed to assess the robustness of the model. For every patient whose symptoms improved or resolved with the strategy of fluticasone first followed by EGD, if necessary, it cost an average of $1078. Similarly, it cost an average of $1171 per patient if EGD with dilation was employed first. Sensitivity analyses indicated that initial treatment with fluticasone was the less costly strategy to improve dysphagia symptoms as long as the effectiveness of fluticasone remains at or above 0.62. Swallowed fluticasone inhaler (followed by EGD with dilation if necessary) is the more economical initial strategy when compared with EGD with dilation first. © 2012 Copyright the Authors. Journal compilation © 2012, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.

  13. Green Building Premium Cost Analysis in Indonesia Using Work Breakdown Structure Method

    NASA Astrophysics Data System (ADS)

    Basten, V.; Latief, Y.; Berawi, M. A.; Riswanto; Muliarto, H.

    2018-03-01

    The concept of green building in the construction industry is indispensable for mitigating environmental issues such as waste, pollution, and carbon emissions. There are some countries that have Green Building rating tools. Indonesia particularly is the country which has Greenship rating tools but the number of Green Building is relatively low. Development of building construction is depended on building investors or owner initiation, so this research is conducted to get the building aspects that have significant effect on the attractiveness using The Green Building Concept. The method in this research is work breakdown structure method that detailing the green building activities. The particular activities will be processed to get the cost elements for the green building achievement that it was targeted to improve better than conventional building. The final result of the study was a very significant work package on green building construction in the city of Indonesia case study.

  14. Economic and epidemiological impact of early antiretroviral therapy initiation in India

    PubMed Central

    Maddali, Manoj V; Dowdy, David W; Gupta, Amita; Shah, Maunank

    2015-01-01

    Introduction Recent WHO guidance advocates for early antiretroviral therapy (ART) initiation at higher CD4 counts to improve survival and reduce HIV transmission. We sought to quantify how the cost-effectiveness and epidemiological impact of early ART strategies in India are affected by attrition throughout the HIV care continuum. Methods We constructed a dynamic compartmental model replicating HIV transmission, disease progression and health system engagement among Indian adults. Our model of the Indian HIV epidemic compared implementation of early ART initiation (i.e. initiation above CD4 ≥350 cells/mm3) with delayed initiation at CD4 ≤350 cells/mm3; primary outcomes were incident cases, deaths, quality-adjusted-life-years (QALYs) and costs over 20 years. We assessed how costs and effects of early ART initiation were impacted by suboptimal engagement at each stage in the HIV care continuum. Results Assuming “idealistic” engagement in HIV care, early ART initiation is highly cost-effective ($442/QALY-gained) compared to delayed initiation at CD4 ≤350 cells/mm3 and could reduce new HIV infections to <15,000 per year within 20 years. However, when accounting for realistic gaps in care, early ART initiation loses nearly half of potential epidemiological benefits and is less cost-effective ($530/QALY-gained). We project 1,285,000 new HIV infections and 973,000 AIDS-related deaths with deferred ART initiation with current levels of care-engagement in India. Early ART initiation in this continuum resulted in 1,050,000 new HIV infections and 883,000 AIDS-related deaths, or 18% and 9% reductions (respectively), compared to current guidelines. Strengthening HIV screening increases benefits of earlier treatment modestly (1,001,000 new infections; 22% reduction), while improving retention in care has a larger modulatory impact (676,000 new infections; 47% reduction). Conclusions Early ART initiation is highly cost-effective in India but only has modest epidemiological benefits at current levels of care-engagement. Improved retention in care is needed to realize the full potential of earlier treatment. PMID:26434780

  15. An initial comparative assessment of orbital and terrestrial central power systems

    NASA Technical Reports Server (NTRS)

    Caputo, R.

    1977-01-01

    A silicon photovoltaic orbital power system, which is constructed from an earth source of materials, is compared to likely terrestrial (fossil, nuclear, and solar) approaches to central power generation around the year 2000. A total social framework is used that considers not only the projection of commercial economics (direct or in internal costs), but also considers external impacts such as research and development investment, health impacts, resource requirements, environment effects, and other social costs.

  16. Habitat and logistic support requirements for the initiation of a space manufacturing enterprise

    NASA Technical Reports Server (NTRS)

    Vajk, J. P.; Engel, J. H.; Shettler, J. A.

    1979-01-01

    A detailed scenario for the initiation of a space manufacturing enterprise using lunar materials to construct solar power satellites (SPS) was developed, with particular attention to habitat design and logistic support requirements. If SPS's can be constructed exclusively from lunar materials, the entire enterprise can be initiated in a 7 year period of launch activity (beginning as early as 1985) using the Space Shuttle and a low-cost, Shuttle-derived heavy lift vehicle. If additional chemical feedstocks must be imported from earth in significant quantities, it may be necessary to bring the next-generation launch vehicle (single-stage-to-orbit) into operation by 1991. The scenario presented features use of the mass-driver reaction engine for orbit-to-orbit transfer of cargos and makes extensive use of the expendable Shuttle external propellant tanks.

  17. 47 CFR 27.1170 - Payment issues.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... emission designator. If a prior coordination notice (PCN) under § 101.103(d) of this chapter is prepared... Bands Cost-Sharing Policies Governing Microwave Relocation from the 2110-2150 Mhz and 2160-2200 Mhz Bands § 27.1170 Payment issues. Prior to initiating operations for a newly constructed site or modified...

  18. Economic aspects of interlocking hollow brick system designed for industrialized building system

    NASA Astrophysics Data System (ADS)

    Tahir, Mahmood Md.; Saggaff, Anis; Ngian, Shek Poi; Sulaiman, Arizu

    2017-11-01

    Construction industry has moved forward into a technology driven where a transition is in progress from conventional method to a more advanced and mechanised system known as the Industrialised Building System (IBS). However, the need to implement the IBS should be well understood by all construction players such as designer, architect, contraction, erectors and construction workers. Therefore, there is a need to educate all these construction players which should be spearheaded by authorities such as Construction Industrial Development Board where enforcement trough building by laws as well as initiative to those that adopt the IBS in their construction. This paper reports on economic aspects of using interlocking hollow brick system in construction as an alternative method offered for Industrialized Building System. The main objective is to address the economic aspects of using interlocking block system in terms of time, costs, and utilization of manpower and to present some of the experimental tests results related to Interlocking Hollow Brick System (IHBS). Example of savings from the use of IHBS is presented in this paper by comparing the construction of two storey terrace house with build-up area of about 200 square meter with conventional construction method of typical reinforced concrete construction (RCC) compared to IHBS. The comparison shows that the implementation of IHBS can reduce construction time, cost, and utilization of man power up to 26.6% compared to the conventional method. Moreover, the construction time using IHBS can also be reduced by up to 50% as compared to the conventional construction.

  19. Low-cost sustainable wall construction system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vohra, A.; Rosenfeld, A.H.

    1998-07-01

    Houses with no wall cavities, such as those made of adobe, stone, brick, or block, have poor thermal properties but are rarely insulated because of the cost and difficulty of providing wall insulation. A simple, low-cost technique using loose-fill indigenous materials has been demonstrated for the construction of highly insulated walls or the retrofit of existing walls in such buildings. Locally available pumice, in sandbags stacked along the exterior wall of an adobe house in New Mexico, added a thermal resistance (R) of 16 F{sm{underscore}bullet}ft{sup 2}{sm{underscore}bullet}h/Btu (2.8 m{sup 2}{sm{underscore}bullet}K/W). The total cost of the sandbag insulation wall retrofit wasmore » $3.76 per square foot ($$40.50/m{sup 2}). Computer simulations of the adobe house using DOE 2.1E show savings of $$275 per year, corresponding to 50% reduction in heating energy consumption. The savings-to-investment ratio ranges from 1.1 to 3.2, so the cost of conserved energy is lower than the price of propane, natural gas and electric heat, making the system cost-effective. Prototype stand-alone walls were also constructed using fly ash and sawdust blown into continuous polypropylene tubing, which was folded between corner posts as it was filled to form the shape of the wall. Other materials could also be used. The inexpensive technique solves the problem of insulating solid-wall hours and constructing new houses without specialized equipment and skills, thereby saving energy, reducing greenhouse gas emissions, and improving comfort for people in many countries. The US Department of Energy (DOE) has filed patent applications on this technology, which is part of a DOE initiative on sustainable building envelope materials and systems.« less

  20. The economics of improving medication adherence in osteoporosis: validation and application of a simulation model.

    PubMed

    Patrick, Amanda R; Schousboe, John T; Losina, Elena; Solomon, Daniel H

    2011-09-01

    Adherence to osteoporosis treatment is low. Although new therapies and behavioral interventions may improve medication adherence, questions are likely to arise regarding their cost-effectiveness. Our objectives were to develop and validate a model to simulate the clinical outcomes and costs arising from various osteoporosis medication adherence patterns among women initiating bisphosphonate treatment and to estimate the cost-effectiveness of a hypothetical intervention to improve medication adherence. We constructed a computer simulation using estimates of fracture rates, bisphosphonate treatment effects, costs, and utilities for health states drawn from the published literature. Probabilities of transitioning on and off treatment were estimated from administrative claims data. Patients were women initiating bisphosphonate therapy from the general community. We evaluated a hypothetical behavioral intervention to improve medication adherence. Changes in 10-yr fracture rates and incremental cost-effectiveness ratios were evaluated. A hypothetical intervention with a one-time cost of $250 and reducing bisphosphonate discontinuation by 30% had an incremental cost-effectiveness ratio (ICER) of $29,571 per quality-adjusted life year in 65-yr-old women initiating bisphosphonates. Although the ICER depended on patient age, intervention effectiveness, and intervention cost, the ICERs were less than $50,000 per quality-adjusted life year for the majority of intervention cost and effectiveness scenarios evaluated. Results were sensitive to bisphosphonate cost and effectiveness and assumptions about the rate at which intervention and treatment effects decline over time. Our results suggests that behavioral interventions to improve osteoporosis medication adherence will likely have favorable ICERs if their efficacy can be sustained.

  1. Comparison of high-speed rail and maglev system costs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rote, D.M.

    1998-07-01

    This paper compares the two modes of transportation, and notes important similarities and differences in the technologies and in how they can be implemented to their best advantage. Problems with making fair comparisons of the costs and benefits are discussed and cost breakdowns based on data reported in the literature are presented and discussed in detail. Cost data from proposed and actual construction projects around the world are summarized and discussed. Results from the National Maglev Initiative and the recently-published Commercial Feasibility Study are included in the discussion. Finally, estimates will be given of the expected cost differences between HSRmore » and maglev systems implemented under simple and complex terrain conditions. The extent to which the added benefits of maglev technology offset the added costs is examined.« less

  2. A cost-utility analysis for prophylactic central neck dissection in clinically nodal-negative papillary thyroid carcinoma.

    PubMed

    Wong, Carlos K H; Lang, Brian Hung-Hin

    2014-03-01

    Although prophylactic central neck dissection (pCND) may reduce future locoregional recurrence after total thyroidectomy (TT) for low-risk papillary thyroid carcinoma (PTC), it is associated with a higher initial morbidity. We aimed to compare the long-term cost-effectiveness between TT with pCND (TT+pCND) and TT alone in the institution's perspective. Our case definition was a hypothetical cohort of 100,000 nonpregnant female patients aged 50 years with a 1.5-cm cN0 PTC within one lobe. A Markov decision tree model was constructed to compare the estimated cost-effectiveness between TT+pCND and TT alone after a 20-year period. Outcome probabilities, utilities, and costs were estimated from the literature. The threshold for cost-effectiveness was set at US$50,000 per quality-adjusted life year (QALY). Sensitivity and threshold analyses were used to examine model uncertainty. Each patient who underwent TT+pCND instead of TT alone cost an extra US$34.52 but gained an additional 0.323 QALY. In fact, in the sensitivity analysis, TT+pCND became cost-effective 9 years after the initial operation. In the threshold analysis, none of the scenarios that could change this conclusion appeared clinically possible or likely. However, TT+pCND became cost-saving (i.e., less costly and more cost-effective) at 20 years if associated permanent vocal cord palsy was kept ≤ 1.37 %, permanent hypoparathyroidism was ≤ 1.20 %, and/or postoperative radioiodine ablation use was ≤ 73.64 %. In the institution's perspective, routine pCND for low-risk PTC began to become cost-effective 9 years after initial surgery and became cost-saving at 20 years if postoperative radioiodine use and/or permanent surgical complications were kept to a minimum.

  3. Construction concepts and validation of the 3D printed UST_2 modular stellarator

    NASA Astrophysics Data System (ADS)

    Queral, V.

    2015-03-01

    High accuracy, geometric complexity and thus high cost of stellarators tend to hinder the advance of stellarator research. Nowadays, new manufacturing methods might be developed for the production of small and middle-size stellarators. The methods should demonstrate advantages with respect common fabrication methods, like casting, cutting, forging and welding, for the construction of advanced highly convoluted modular stellarators. UST2 is a small modular three period quasi-isodynamic stellarator of major radius 0.26 m and plasma volume 10 litres being currently built to validate additive manufacturing (3D printing) for stellarator construction. The modular coils are wound in grooves defined on six 3D printed half period frames designed as light truss structures filled by a strong filler. A geometrically simple assembling configuration has been concocted for UST2 so as to try to lower the cost of the device while keeping the positioning accuracy of the different elements. The paper summarizes the construction and assembling concepts developed, the devised positioning methodology, the design of the coil frames and positioning elements and, an initial validation of the assembling of the components.

  4. Model Based Iterative Reconstruction for Bright Field Electron Tomography (Postprint)

    DTIC Science & Technology

    2013-02-01

    which is based on the iterative coordinate descent (ICD), works by constructing a substitute to the original cost4 at every point, and minimizing this...using Beer’s law. Thus the projection integral corresponding to the ith measurement is given by log ( λD λi ) . There can be cases in which the dosage λD...Inputs: Measurements g, Initial reconstruction f ′, Initial dosage d′, Fraction of entries to reject R %Outputs: Reconstruction f̂ and dosage parameter d̂

  5. The space elevator: a new tool for space studies.

    PubMed

    Edwards, Bradley C

    2003-06-01

    The objective has been to develop a viable scenario for the construction, deployment and operation of a space elevator using current or near future technology. This effort has been primarily a paper study with several experimental tests of specific systems. Computer simulations, engineering designs, literature studies and inclusion of existing programs have been utilized to produce a design for the first space elevator. The results from this effort illustrate a viable design using current and near-term technology for the construction of the first space elevator. The timeline for possible construction is within the coming decades and estimated costs are less than $10 B. The initial elevator would have a 5 ton/day capacity and operating costs near $100/lb for payloads going to any Earth orbit or traveling to the Moon, Mars, Venus or the asteroids. An operational space elevator would allow for larger and much longer-term biological space studies at selectable gravity levels. The high-capacity and low operational cost of this system would also allow for inexpensive searches for life throughout our solar system and the first tests of environmental engineering. This work is supported by a grant from the NASA Institute for Advanced Concepts (NIAC).

  6. 25 CFR 700.467 - Construction costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

  7. 25 CFR 700.467 - Construction costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

  8. 25 CFR 700.467 - Construction costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

  9. Learning Laboratory Chemistry through Electronic Sensors, a Microprocessor, and Student Enabling Software: A Preliminary Demonstration

    ERIC Educational Resources Information Center

    Zhang, Qing; Brode, Ly; Cao, Tingting; Thompson, J. E.

    2017-01-01

    We describe the construction and initial demonstration of a new instructional tool called ROXI (Research Opportunity through eXperimental Instruction). The system interfaces a series of electronic sensors to control software via the Arduino platform. The sensors have been designed to enable low-cost data collection in laboratory courses. Data are…

  10. House log drying rates in southeast Alaska for covered and uncovered softwood logs

    Treesearch

    David Nicholls; Allen Brackley

    2009-01-01

    Log moisture content has an important impact on many aspects of log home construction, including log processing, transportation costs, and dimensional stability in use. Air-drying times for house logs from freshly harvested trees can depend on numerous factors including initial moisture content, log diameter, bark condition, and environmental conditions during drying....

  11. Theoretical framework of the causes of construction time and cost overruns

    NASA Astrophysics Data System (ADS)

    Ullah, K.; Abdullah, A. H.; Nagapan, S.; Suhoo, S.; Khan, M. S.

    2017-11-01

    Any construction practitioner fundamental goal is to complete the projects within estimated duration and budgets, and expected quality targets. However, time and cost overruns are regular and universal phenomenon in construction projects and the construction projects in Malaysia has no exemption from the problems of time overrun and cost overrun. In order to accomplish the successful completion of construction projects on specified time and within planned cost, there are various factors that should be given serious attention so that issues such as time and cost overrun can be addressed. This paper aims to construct a framework for the causes of time overrun and cost overrun in construction projects of Malaysia. Based on the relevant literature review, causative factors of time overrun and cost overrun in Malaysian construction projects are summarized and the theoretical frameworks of the causes of construction time overrun and cost overrun is constructed. The developed frameworks for construction time and cost overruns based on the existing literature will assist the construction practitioners to plan the efficient approaches for achieving successful completion of the projects.

  12. Comparison of Navy and Private-Sector Construction Costs

    DTIC Science & Technology

    1997-09-01

    contracts are comparable to private - sector construction costs. This report compares those costs. The report includes a description of the methodology...costs of complying with federal contracting requirements as compared with the costs of similar projects completed under typical private - sector contracts...The study found that the costs of facilities constructed under Navy contracts compare favorably to private - sector construction costs for similar

  13. Locally optimal transfer trajectories between libration point orbits using invariant manifolds

    NASA Astrophysics Data System (ADS)

    Davis, Kathryn E.

    2009-12-01

    Techniques from dynamical systems theory and primer vector theory have been applied to the construction of locally optimal transfer trajectories between libration point orbits. When two libration point orbits have different energies, it has been found that the unstable manifold of the first orbit can be connected to the stable manifold of the second orbit with a bridging trajectory. A bounding sphere centered on the secondary, with a radius less than the radius of the sphere of influence of the secondary, was used to study the stable and unstable manifold trajectories. It was numerically demonstrated that within the bounding sphere, the two-body parameters of the unstable and stable manifold trajectories could be analyzed to locate low transfer costs. It was shown that as the two-body parameters of an unstable manifold trajectory more closely matched the two-body parameters of a stable manifold trajectory, the total DeltaV necessary to complete the transfer decreased. Primer vector theory was successfully applied to a transfer to determine the optimal maneuvers required to create the bridging trajectory that connected the unstable manifold of the first orbit to the stable manifold of the second orbit. Transfer trajectories were constructed between halo orbits in the Sun-Earth and Earth-Moon three-body systems. Multiple solutions were found between the same initial and final orbits, where certain solutions retraced interior portions of the trajectory. All of the trajectories created satisfied the conditions for optimality. The costs of transfers constructed using invariant manifolds were compared to the costs of transfers constructed without the use of invariant manifolds, when data was available. In all cases, the total cost of the transfers were significantly lower when invariant manifolds were used in the transfer construction. In many cases, the transfers that employed invariant manifolds were three to four times more efficient, in terms of fuel expenditure, than the transfer that did not. The decrease in transfer cost was accompanied by an increase in transfer time of flight. Transfers constructed in the Earth-Moon system were shown to be particularly viable for lunar navigation and communication constellations, as excellent coverage of the lunar surface can be achieved during the transfer.

  14. Ceftaroline fosamil use in hospitalized patients with acute bacterial skin and skin structure infections: Budget impact analysis from a hospital perspective.

    PubMed

    Huang, Xingyue; Beresford, Eric; Lodise, Thomas; Friedland, H David

    2013-06-15

    The budgetary impact of adding ceftaroline fosamil to a hospital formulary for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) was evaluated. A three-year hospital budget impact model was constructed with three initial treatment options for ABSSSIs: ceftaroline fosamil, vancomycin plus aztreonam, and other vancomycin-containing regimens. The target population was hospitalized adult patients with an ABSSSI. Clinical cure rates with initial treatment were assumed to be similar to those from ceftaroline fosamil clinical trials. Patients who did not respond to initial treatment were assumed to be treated successfully with second-line antimicrobial therapy. Length of stay and cost per hospital day (by success or failure with initial treatment) were estimated based on a large database from more than 100 U.S. hospitals. Other model inputs included the annual number of ABSSSI admissions, projected annual case growth rate, proportion of ABSSSI target population receiving vancomycin-containing regimen, expected proportion of ABSSSI target population to be treated with ceftaroline fosamil, drug acquisition cost, cost of antibiotic administration, and cost of vancomycin monitoring. Sensitivity analysis using 95% confidence limits of clinical cure rates was also performed. The estimated total cost of care for treating a patient with an ABSSSI was $395 lower with ceftaroline fosamil ($15,087 versus $15,482) compared with vancomycin plus aztreonam and $72 lower ($15,087 versus $15,159) compared with other vancomycin-containing regimens. Model estimates indicated that adding ceftaroline fosamil to the hospital formulary would not have a negative effect on a hospital's budget for ABSSSI treatment.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Arizona. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Hawaii. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Connecticut. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  18. Life cycle cost modeling of conceptual space vehicles

    NASA Technical Reports Server (NTRS)

    Ebeling, Charles

    1993-01-01

    This paper documents progress to date by the University of Dayton on the development of a life cycle cost model for use during the conceptual design of new launch vehicles and spacecraft. This research is being conducted under NASA Research Grant NAG-1-1327. This research effort changes the focus from that of the first two years in which a reliability and maintainability model was developed to the initial development of a life cycle cost model. Cost categories are initially patterned after NASA's three axis work breakdown structure consisting of a configuration axis (vehicle), a function axis, and a cost axis. The focus will be on operations and maintenance costs and other recurring costs. Secondary tasks performed concurrent with the development of the life cycle costing model include continual support and upgrade of the R&M model. The primary result of the completed research will be a methodology and a computer implementation of the methodology to provide for timely cost analysis in support of the conceptual design activities. The major objectives of this research are: to obtain and to develop improved methods for estimating manpower, spares, software and hardware costs, facilities costs, and other cost categories as identified by NASA personnel; to construct a life cycle cost model of a space transportation system for budget exercises and performance-cost trade-off analysis during the conceptual and development stages; to continue to support modifications and enhancements to the R&M model; and to continue to assist in the development of a simulation model to provide an integrated view of the operations and support of the proposed system.

  19. Design and cloning strategies for constructing shRNA expression vectors

    PubMed Central

    McIntyre, Glen J; Fanning, Gregory C

    2006-01-01

    Background Short hairpin RNA (shRNA) encoded within an expression vector has proven an effective means of harnessing the RNA interference (RNAi) pathway in mammalian cells. A survey of the literature revealed that shRNA vector construction can be hindered by high mutation rates and the ensuing sequencing is often problematic. Current options for constructing shRNA vectors include the use of annealed complementary oligonucleotides (74 % of surveyed studies), a PCR approach using hairpin containing primers (22 %) and primer extension of hairpin templates (4 %). Results We considered primer extension the most attractive method in terms of cost. However, in initial experiments we encountered a mutation frequency of 50 % compared to a reported 20 – 40 % for other strategies. By modifying the technique to be an isothermal reaction using the DNA polymerase Phi29, we reduced the error rate to 10 %, making primer extension the most efficient and cost-effective approach tested. We also found that inclusion of a restriction site in the loop could be exploited for confirming construct integrity by automated sequencing, while maintaining intended gene suppression. Conclusion In this study we detail simple improvements for constructing and sequencing shRNA that overcome current limitations. We also compare the advantages of our solutions against proposed alternatives. Our technical modifications will be of tangible benefit to researchers looking for a more efficient and reliable shRNA construction process. PMID:16396676

  20. Business Management in Sustainable Buildings: Ankara-Turkey Case

    NASA Astrophysics Data System (ADS)

    Kutay Karaca, Neşet; Burcu Gültekin, Arzuhan

    2017-10-01

    The concept of the sustainability is described as efficiently and effectively consuming of exhaustible and recyclable sources of the world. A sustainable building implements sustainability criteria in its life cycle, and business management is the process by which an organization uses its resources in the most efficient way to reach its goal. From the beginning, sustainable building proves their differences from the conventional buildings. Sustainable buildings are resource-efficient and environmentally responsible structures in terms of energy consumption, construction principles, siting, renovation and maintenance throughout its life cycle while conventional buildings are more traditional in these matters. The differences are observable especially in costs and expenditures. It is possible and feasible to compare and contrast the design, construction and management costs of both types of structures. Thence, contributions of sustainable buildings are priced favourably in terms of ecological and sociological aspects. In this context, a prospective projection can be made considering the extra costs of sustainable structures, as well as the consumption profits due to the use of less energy than conventional construction. Considering this, it is possible to project consumption savings in long term. By calculating a forward-looking net cash flow projection, it can be forecasted how much time it will take to cover the extra cost. When making decisions, investors always contemplate maximum profitability. Within the scope of this study, costs of sustainable and conventional buildings will be compared and contrasted through precedence of a sustainable building certificated and non-certificated building. It will be analysed in which time period the initial cost difference between them will be compensated totally and partially. Furthermore, an efficiency analyses will be done in the scope of the necessities and expenses of these businesses.

  1. An innovative time-cost-quality tradeoff modeling of building construction project based on resource allocation.

    PubMed

    Hu, Wenfa; He, Xinhua

    2014-01-01

    The time, quality, and cost are three important but contradictive objectives in a building construction project. It is a tough challenge for project managers to optimize them since they are different parameters. This paper presents a time-cost-quality optimization model that enables managers to optimize multiobjectives. The model is from the project breakdown structure method where task resources in a construction project are divided into a series of activities and further into construction labors, materials, equipment, and administration. The resources utilized in a construction activity would eventually determine its construction time, cost, and quality, and a complex time-cost-quality trade-off model is finally generated based on correlations between construction activities. A genetic algorithm tool is applied in the model to solve the comprehensive nonlinear time-cost-quality problems. Building of a three-storey house is an example to illustrate the implementation of the model, demonstrate its advantages in optimizing trade-off of construction time, cost, and quality, and help make a winning decision in construction practices. The computational time-cost-quality curves in visual graphics from the case study prove traditional cost-time assumptions reasonable and also prove this time-cost-quality trade-off model sophisticated.

  2. 18 CFR 367.52 - Overhead construction costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ACT Service Company Property Instructions § 367.52 Overhead construction costs. (a) All overhead construction costs, such as engineering, supervision, general office salaries and expenses, construction... costs. 367.52 Section 367.52 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...

  3. 18 CFR 367.52 - Overhead construction costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ACT Service Company Property Instructions § 367.52 Overhead construction costs. (a) All overhead construction costs, such as engineering, supervision, general office salaries and expenses, construction... costs. 367.52 Section 367.52 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...

  4. Analysis of Tactical Automation Requirements for the Maneuver Functional Area.

    DTIC Science & Technology

    1987-11-06

    34Big 5" format for each alternative ("Big 5" format includes: development, production , military construction, fielding, and sustainment). 1-6...h a1 based upon recurring unit production costs per system and initial spares plus sustainment (i.e., materiel and labor) costs. (2) Figure 2-15...GRAND TOTALS: C 0 24 C C ’ IT-. SV -II-4 %#g Np MOE : .EVEL TE OF T ;TAA 92; 1-As IT E Th DESC-NATED 3-AR : (V 1) M)2 fViI ’ M.)’S 17 20 o,. D:v CAVALRY

  5. Occupational injury costs and alternative employment in construction trades.

    PubMed

    Waehrer, Geetha M; Dong, Xiuwen S; Miller, Ted; Men, Yurong; Haile, Elizabeth

    2007-11-01

    To present the costs of fatal and non-fatal days-away-from-work injuries in 50 construction occupations. Our results also provide indirect evidence on the cost exposure of alternative construction workers such as independent contractors, on-call or day labor, contract workers, and temporary workers. We combine data from the Bureau of Labor Statistics on average annual incidence from 2000 to 2002 with updated per-case costs from an existing cost model for occupational injuries. The Current Population Survey provides data on the percentage of alternative construction workers. Construction laborers and carpenters were the two costliest occupations, with 40% of the industry's injury costs. The 10 costliest construction occupations also have a high percentage of alternative workers. The construction industry has both a high rate of alternative employment and high costs of work injury. Alternative workers, often lacking workers' compensation, are especially exposed to injury costs.

  6. Using Sustainable Development as a Competitive Strategy

    NASA Astrophysics Data System (ADS)

    Spearman, Pat

    Sustainable development reduces construction waste by 43%, generating 50% cost savings. Residential construction executives lacking adequate knowledge regarding the benefits of sustainable development practices are at a competitive disadvantage. Drawing from the diffusion of innovation theory, the purpose of this qualitative case study was to explore knowledge acquisition within the bounds of sustainable residential construction. The purposive sample size of 11 executive decision makers fulfilled the sample size requirements and enabled the extraction of meaningful data. Participants were members of the National Home Builders Association and had experience of a minimum of 5 years in residential construction. The research question addressed how to improve knowledge acquisition relating to the cost benefits of building green homes and increase the adoption rate of sustainable development among residential builders. Data were collected via semistructured telephone interviews, field observation, and document analysis. Transcribed data were validated via respondent validation, coded into 5 initial categories aligned to the focus of the research, then reduced to 3 interlocking themes of environment, competitive advantage, and marketing. Recommendations include developing comprehensive public policies, horizontal and vertical communications networks, and green banks to capitalize sustainable development programs to improve the diffusion of green innovation as a competitive advantage strategy. Business leaders could benefit from this data by integrating sustainable development practices into their business processes. Sustainable development reduces operational costs, increases competitive advantage for builders, and reduces greenhouse gas emissions. Implications for social change increase energy independence through conservation and developing a legislative policy template for comprehensive energy strategies. A comprehensive energy strategy promotes economic development, technological gains in all business sectors within the energy industry, and reduces energy costs for consumers.

  7. Constructibility Challenges for Perimeter Control Blasting and Slope Development in Shale and Other "Weak" Rocks

    NASA Astrophysics Data System (ADS)

    Scarpato, D. J.

    2016-02-01

    Slope construction in shale can present some interesting challenges for geotechnical design engineers and contractors alike. There are challenges that can be expected and designed for; however, all too frequently, such challenges manifest themselves as "surprises" in the field. Common constructibility challenges can include drill hole deviation during drilling for controlled blasting; and, excavation slope instability arising from inconsistent perimeter control drilling. Drill hole deviation results from the cumulative effects from both drilling mechanics and rock mass conditions. Once a hole has initiated the deviation trajectory, it is difficult to rectify drill steel position. Although such challenges are not necessarily unique to shale, they are often exacerbated by weak, weathered and transversely isotropic nature of bedrock conditions. All too often, the working assumption is that shale is "soft" and easily excavatable; however, this blanket assumption can prove to be costly. This paper is intended to provide design professionals and contractors with the practical considerations needed to avoid the "surprises" associated with drill hole deviation, and minimize the potential for costly claims.

  8. 49 CFR 262.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., including architectural and engineering costs, and costs associated with compliance with the National.... Allowable costs means those project costs for which Federal funding may be expended under this part. Only construction and construction-related costs will be allowable. Construction means supervising, inspecting...

  9. 49 CFR 262.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., including architectural and engineering costs, and costs associated with compliance with the National.... Allowable costs means those project costs for which Federal funding may be expended under this part. Only construction and construction-related costs will be allowable. Construction means supervising, inspecting...

  10. 49 CFR 262.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., including architectural and engineering costs, and costs associated with compliance with the National.... Allowable costs means those project costs for which Federal funding may be expended under this part. Only construction and construction-related costs will be allowable. Construction means supervising, inspecting...

  11. Rethinking the laryngopharyngeal reflux treatment algorithm: Evaluating an alternate empiric dosing regimen and considering up-front, pH-impedance, and manometry testing to minimize cost in treating suspect laryngopharyngeal reflux disease.

    PubMed

    Carroll, Thomas L; Werner, Astrid; Nahikian, Kael; Dezube, Aaron; Roth, Douglas F

    2017-10-01

    Empiric proton pump inhibitor (PPI) trials for laryngopharyngeal reflux (LPR) are common. A majority of the patients respond to acid suppression. This work intends to evaluate once-daily, 40 mg omeprazole and once-nightly, 300 mg ranitidine (QD/QHS) dosing as an alternative regimen, and use this study's cohort to evaluate empiric regimens prescribed for LPR as compared to up-front testing with pH impedance multichannel intraluminal impedance (MII) with dual pH probes and high-resolution manometry (HRM) for potential cost minimization. Retrospective cohort review and cost minimization study. A chart review identified patients diagnosed with LPR. All subjects were treated sequentially and outcomes recorded. Initial QD/QHS dosing increased after 3 months to BID if no improvement and ultimately prescribed MII and HRM if they failed BID dosing. Decision tree diagrams were constructed to determine costs of two empiric regimens and up-front MII and HRM. Ninety-seven subjects met the criteria. Responders and nonresponders to empiric therapy were identified. Seventy-two subjects (74%) responded. Forty-eight (67% of responders and 49% of all) improved with QD/QHS dosing. Forty-nine (51%) subjects escalated to BID dosing. Twenty-four subjects (33% of responders and 25% of all) improved on BID therapy. Twenty-five subjects (26%) did not respond to acid suppression. Average weighted cost was $1,897.00 per patient for up-front testing, $3,033.00 for initial BID, and $3,366.00 for initial QD/QHS. An alternate QD/QHS regimen improved the majority who presented with presumed LPR. Cost estimates demonstrate that the QD/QHS regimen was more expensive than the initial BID high-dose PPI for 6 months. Overall per-patient cost appears less with up-front MII and HRM. 4. Laryngoscope, 127:S1-S13, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  12. Modelling the costs and consequences of treating paediatric faecal impaction in Australia.

    PubMed

    Guest, Julian F; Clegg, John P

    2006-01-01

    To compare the costs and consequences of using oral macrogol 3350 plus electrolytes (macrogol 3350; Movicol) compared to enemas/suppositories, manual evacuation and naso-gastric administration of macrogol (NGA-PEG) lavage solution in treating paediatric faecal impaction in Australia. A decision model was constructed using published clinical outcomes, utilities and clinician-derived resource utilisation estimates. The model was used to determine the expected Commonwealth and parent costs associated with each treatment over the period of disimpaction and 12 weeks post-disimpaction, in Australian dollars at 2003/2004 prices. 92% of oral macrogol 3350-treated patients are expected to be disimpacted within 6 days following initial treatment, compared with 79% of patients treated with enemas and suppositories who are expected to be disimpacted within 8 days. All patients are expected to be disimpacted within 5 days following a manual evacuation and within 2 days following NGA-PEG. The level of health gain at 12 weeks post-disimpaction irrespective of treatment for disimpaction and subsequent maintenance is expected to be the same; the expected quality-adjusted life years (QALYs) being 0.20 (95% CI: 0.17; 0.23). Starting treatment with oral macrogol 3350 in an outpatient setting is expected to lead to a Commonwealth cost of $758, compared to $1838 with NGA-PEG, $2125 with enemas and suppositories, $3931 with oral macrogol 3350 in an inpatient setting and $4478 with manual evacuation. Resource use associated with maintenance following initial disimpaction is expected to be broadly similar, irrespective of initial laxative. Hence, the expected Commonwealth cost is primarily affected by the treatment used to initially disimpact a patient. Expected parents' costs are expected to be comparable irrespective of treatment ranging from $89 to $112 per patient. Within the limitations of our model, using oral macrogol 3350 in an outpatient setting for treating faecally impacted children affords a cost effective alternative compared to the other treatments investigated.

  13. Construction Cost Growth for New Department of Energy Nuclear Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kubic, Jr., William L.

    Cost growth and construction delays are problems that plague many large construction projects including the construction of new Department of Energy (DOE) nuclear facilities. A study was conducted to evaluate cost growth of large DOE construction projects. The purpose of the study was to compile relevant data, consider the possible causes of cost growth, and recommend measures that could be used to avoid extreme cost growth in the future. Both large DOE and non-DOE construction projects were considered in this study. With the exception of Chemical and Metallurgical Research Building Replacement Project (CMRR) and the Mixed Oxide Fuel Fabrication Facilitymore » (MFFF), cost growth for DOE Nuclear facilities is comparable to the growth experienced in other mega construction projects. The largest increase in estimated cost was found to occur between early cost estimates and establishing the project baseline during detailed design. Once the project baseline was established, cost growth for DOE nuclear facilities was modest compared to non-DOE mega projects.« less

  14. An Innovative Time-Cost-Quality Tradeoff Modeling of Building Construction Project Based on Resource Allocation

    PubMed Central

    2014-01-01

    The time, quality, and cost are three important but contradictive objectives in a building construction project. It is a tough challenge for project managers to optimize them since they are different parameters. This paper presents a time-cost-quality optimization model that enables managers to optimize multiobjectives. The model is from the project breakdown structure method where task resources in a construction project are divided into a series of activities and further into construction labors, materials, equipment, and administration. The resources utilized in a construction activity would eventually determine its construction time, cost, and quality, and a complex time-cost-quality trade-off model is finally generated based on correlations between construction activities. A genetic algorithm tool is applied in the model to solve the comprehensive nonlinear time-cost-quality problems. Building of a three-storey house is an example to illustrate the implementation of the model, demonstrate its advantages in optimizing trade-off of construction time, cost, and quality, and help make a winning decision in construction practices. The computational time-cost-quality curves in visual graphics from the case study prove traditional cost-time assumptions reasonable and also prove this time-cost-quality trade-off model sophisticated. PMID:24672351

  15. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Texas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Texas. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  16. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Minnesota

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Minnesota. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  17. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Indiana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Indiana. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  18. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Florida

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Florida. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  19. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Maine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Maine. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  20. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Vermont

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Vermont. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  1. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Michigan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Michigan. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  2. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Alabama

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Alabama. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  3. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of New Hampshire

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of New Hampshire. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology usedmore » in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  4. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of New Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of New Mexico. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology usedmore » in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  5. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Colorado. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  6. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Washington

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Washington. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  7. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Montana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Montana. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  8. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the District of Columbia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the District of Columbia. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  9. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Massachusetts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Massachusetts. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  10. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Oregon

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Oregon. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  11. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Wisconsin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Wisconsin. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  12. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Ohio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Ohio. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  13. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of South Carolina

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of South Carolina. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology usedmore » in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  14. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of North Carolina

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of North Carolina. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology usedmore » in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  15. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Iowa

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, Philip R.; Athalye, Rahul A.; Xie, YuLong

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Iowa. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used inmore » the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.« less

  16. The Impacts of Thawing Permafrost and Climate Change on USAF Infrastructure Within Northern Tier Bases

    NASA Astrophysics Data System (ADS)

    Graboski, A. J.

    2016-12-01

    The Department of Defense (DoD) is planning over $600M in military construction on Eielson Air Force Base (AFB) within the next three fiscal years. Although many studies have been conducted on permafrost and climate change, the future of our climate as well as any impacts on arctic infrastructure, remains unclear. This research focused on future climate predictions to determine likely scenarios for the United States Air Force's Strategic Planners to consider. This research also looked at various construction methods being used by industry to glean best practices to incorporate into future construction in order to determine cost factors to consider when permafrost soils may be encountered. The most recent 2013 International Panel on Climate Change (IPCC) report predicts a 2.2ºC to 7.8ºC temperature rise in Arctic regions by the end of the 21st Century in the Representative Concentration Pathways, (RCP4.5) emissions scenario. A regression model was created using archived surface observations from 1944 to 2016. Initial analysis using regression/forecast techniques show a 1.17ºC temperature increase in the Arctic by the end of the 21st Century. Historical DoD construction data was then used to determine an appropriate cost factor. Applying statistical tests to the adjusted climate predictions supports continued usage of current DoD cost factors of 2.13 at Eielson and 2.97 at Thule AFBs as they should be sufficient when planning future construction projects in permafrost rich areas. These cost factors should allow planners the necessary funds to plan foundation mitigation techniques and prevent further degradation of permafrost soils around airbase infrastructure. This current research focused on Central Alaska while further research is recommended on the Alaskan North Slope and Greenland to determine climate change impacts on critical DoD infrastructure.

  17. Research on cost control and management in high voltage transmission line construction

    NASA Astrophysics Data System (ADS)

    Xu, Xiaobin

    2017-05-01

    Enterprises. The cost control is of vital importance to the construction enterprises. It is the key to the profitability of the transmission line project, which is related to the survival and development of the electric power construction enterprises. Due to the long construction line, complex and changeable construction terrain as well as large construction costs of transmission line, it is difficult for us to take accurate and effective cost control on the project implementation of entire transmission line. Therefore, the cost control of transmission line project is a complicated and arduous task. It is of great theoretical and practical significance to study the cost control scheme of transmission line project by a more scientific and efficient way. Based on the characteristics of the construction project of the transmission line project, this paper analyzes the construction cost structure of the transmission line project and the current cost control problem of the transmission line project, and demonstrates the necessity and feasibility of studying the cost control scheme of the transmission line project more accurately. In this way, the dynamic cycle cost control process including plan, implementation, feedback, correction, modification and re-implement is achieved to realize the accurate and effective cost control of entire electric power transmission line project.

  18. Initial technical environmental, and economic evaluation of space solar power concepts. Volume 2: Detailed report

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The SPS concepts which appear to be technically feasible are discussed in terms of the economic viability and competitive costs with other energy sources. The concepts discussed include: power station, microwave reception and conversion, space construction and maintenance, space transportation, and program costs and analysis. The conclusions presented include: (1) The maximum output of an individual microwave transmission link to earth is about 5 GW. (2) The mass of 10 GW SPS is between 47,000,000 and 124,000,00 kg. (3) The silicon solar cell arrays make up well over half the weight and cost of the satellite. (4) The SPS in equatorial orbit will be eclipsed by the earth and by other satellites.

  19. Energy Recovery Hydropower: Prospects for Off-Setting Electricity Costs for Agricultural, Municipal, and Industrial Water Providers and Users; July 2017 - September 2017

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levine, Aaron L.; Curtis, Taylor L.; Johnson, Kurt

    Energy recovery hydropower is one of the most cost-effective types of new hydropower development because it is constructed utilizing existing infrastructure, and it is typically able to complete Federal Energy Regulatory Commission (FERC) review in 60 days. Recent changes in federal and state policy have supported energy recovery hydropower. In addition, some states have developed programs and policies to support energy recovery hydropower, including resource assessments, regulatory streamlining initiatives, and grant and loan programs to reduce project development costs. This report examines current federal and state policy drivers for energy recovery hydropower, reviews market trends, and looks ahead at futuremore » federal resource assessments and hydropower reform legislation.« less

  20. Development of Economic Factors in Tunnel Construction

    DOT National Transportation Integrated Search

    1977-12-01

    The escalating cost of underground construction of urban transportation systems has made transit planning, especially construction cost estimating, difficult. This is a study of the cost of construction of underground, rapid transit tunnels in soft g...

  1. Low-cost vibration sensor based on dual fiber Bragg gratings and light intensity measurement.

    PubMed

    Gao, Xueqing; Wang, Yongjiao; Yuan, Bo; Yuan, Yinquan; Dai, Yawen; Xu, Gang

    2013-09-20

    A vibration monitoring system based on light intensity measurement has been constructed, and the designed accelerometer is based on steel cantilever frame and dual fiber Bragg gratings (FBGs). By using numerical simulations for the dual FBGs, the dependence relationship of the area of main lobes on the difference of initial central wavelengths is obtained and the most optimal choice for the initial value and the vibration amplitude of the difference of central wavelengths of two FBGs is suggested. The vibration monitoring experiments are finished, and the measured data are identical to the simulated results.

  2. Costs of occupational injuries in construction in the United States.

    PubMed

    Waehrer, Geetha M; Dong, Xiuwen S; Miller, Ted; Haile, Elizabeth; Men, Yurong

    2007-11-01

    This paper presents costs of fatal and nonfatal injuries for the construction industry using 2002 national incidence data from the Bureau of Labor Statistics and a comprehensive cost model that includes direct medical costs, indirect losses in wage and household productivity, as well as an estimate of the quality of life costs due to injury. Costs are presented at the three-digit industry level, by worker characteristics, and by detailed source and event of injury. The total costs of fatal and nonfatal injuries in the construction industry were estimated at $11.5 billion in 2002, 15% of the costs for all private industry. The average cost per case of fatal or nonfatal injury is $27,000 in construction, almost double the per-case cost of $15,000 for all industry in 2002. Five industries accounted for over half the industry's total fatal and nonfatal injury costs. They were miscellaneous special trade contractors (SIC 179), followed by plumbing, heating and air-conditioning (SIC 171), electrical work (SIC 173), heavy construction except highway (SIC 162), and residential building construction (SIC 152), each with over $1 billion in costs.

  3. Conceptual design study of improved automotives gas turbine powertrain

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Twenty-two candidate engine concepts and nineteen transmission concepts. Screening of these concepts, predominantly for fuel economy, cost and technical risk, resulted in a recommended powertrain consisting of a single-shaft engine, with a ceramic radial turbine rotor, connected through a differential split-power transmission utilizing a variable stator torque converter and a four speed automatic gearbox. Vehicle fuel economy and performance projections, preliminary design analyses and installation studies in a were completed. A cost comparison with the conventional spark ignited gasoline engine showed that the turbine engine would be more expensive initially, however, lifetime cost of ownership is in favor of the gas turbine. A powertrain research and development plan was constructed to gain information on timing and costs to achieve the required level of technology and demonstrate the engine in a vehicle by the year 1983.

  4. Cost-effectiveness of different strategies to manage patients with sciatica.

    PubMed

    Fitzsimmons, Deborah; Phillips, Ceri J; Bennett, Hayley; Jones, Mari; Williams, Nefyn; Lewis, Ruth; Sutton, Alex; Matar, Hosam E; Din, Nafees; Burton, Kim; Nafees, Sadia; Hendry, Maggie; Rickard, Ian; Wilkinson, Claire

    2014-07-01

    The aim of this paper is to estimate the relative cost-effectiveness of treatment regimens for managing patients with sciatica. A deterministic model structure was constructed based on information from the findings from a systematic review of clinical effectiveness and cost-effectiveness, published sources of unit costs, and expert opinion. The assumption was that patients presenting with sciatica would be managed through one of 3 pathways (primary care, stepped approach, immediate referral to surgery). Results were expressed as incremental cost per patient with symptoms successfully resolved. Analysis also included incremental cost per utility gained over a 12-month period. One-way sensitivity analyses were used to address uncertainty. The model demonstrated that none of the strategies resulted in 100% success. For initial treatments, the most successful regime in the first pathway was nonopioids, with a probability of success of 0.613. In the second pathway, the most successful strategy was nonopioids, followed by biological agents, followed by epidural/nerve block and disk surgery, with a probability of success of 0.996. Pathway 3 (immediate surgery) was not cost-effective. Sensitivity analyses identified that the use of the highest cost estimates results in a similar overall picture. While the estimates of cost per quality-adjusted life year are higher, the economic model demonstrated that stepped approaches based on initial treatment with nonopioids are likely to represent the most cost-effective regimens for the treatment of sciatica. However, development of alternative economic modelling approaches is required. Copyright © 2014 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  5. Improvements in SMR Modular Construction through Supply Chain Optimization and Lessons Learned

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White III, Chelsea C.; Petrovic, Bojan

    Affordable energy is a critical societal need. Capital construction cost is a significant portion of nuclear energy cost. By controlling and reducing cost, companies can build more competitive nuclear power plants and hence provide access to more affordable energy. Modular construction provides an opportunity to reduce the cost of construction, and as projects scale up in number, the cost of each unit can be further reduced. The objective of this project was to advance design and construction methods for manufacturing Small Modular Reactors (SMRs), and in particular to improve modular construction techniques and develop best practices for designing and operatingmore » supply chains that take advantage of these techniques. The overarching objectives were to accelerate the construction schedule and reduce its variability, reduce the cost of construction, reduce interest costs accrued during construction (IDC), and thus enhance the economic attractiveness of SMRs. Our fundamental measure of merit was total capital investment cost (TCIC). To achieve these objectives, this project developed a decision support system, EVAL, to support identifying, addressing, and resolving or ameliorating challenges and deficiencies in the current modular construction approach. The results of this effort were consistent with the facts that the cost of a construction activity is often smallest when accomplished in the factory, greatest when accomplished at the construction site, and at an intermediate level when accomplished at an assembly area close to the construction site. Further, EVAL can aid in providing insight into ways to reduce waste, improve quality, efficiency, and throughput and reflects the fact that the more done early in the construction process, i.e., in the factory, the more upfront funding is required and hence the more IDC will be accrued. The analysis has lead to a better understanding of circumstances under which modular construction performed mainly in the factory will result in lower expected total cost, relative to more traditional, on-site construction procedures. Further, we anticipate that EVAL can be used to gain insight regarding what role standardization can play in order for modularization to be most effectively defined. Such results would ultimately benefit all (small and large) new nuclear construction.« less

  6. Prevailing Wage Rates: The Effects on School Construction Costs, Levels of Taxation, and State Reimbursements.

    ERIC Educational Resources Information Center

    Keller, Edward C.; Hartman, William T.

    2001-01-01

    Results of study of impact of Pennsylvania Prevailing Wage Act on 25 school-construction project costs from 1992-97 and effect thereof on local school districts' taxes. All districts had higher construction costs and property taxes. Projects increased construction costs for the Commonwealth and recommends revisions in prevailing wage-rate law.…

  7. Exceptional cost effectiveness of the Solarcrete construction system with hybrid solar for McCormick's piano showroom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levy, M.T.

    1980-01-01

    A new building was designed to house Northeast Indiana's largest keyboard instrument showroom, offices, and warehouse. The 7653 SF building faces 8/sup 0/ east of south in a climate of 41/sup 0/ NL, 6717 DD, and 49% of possible sunshine during the heating season. The energy system may be described as hybrid using an integration of passive direct gain, water thermal storage with earth contact, evaporative cooling, and water source heat pump. The thermal envelope of the building employs the Solarcrete method devised to render improved thermal performance and reduce labor time, skill, and effort resulting in both initial andmore » life-cycle savings. The initial cost savings on the building including the tax credit of $11,076 was 33% or $79,076 LESS than a conventional building. The owners have realized 84% energy savings on the annual usage for the first year of operation.« less

  8. Cost-effectiveness analysis of treatment strategies for initial Clostridium difficile infection.

    PubMed

    Varier, R U; Biltaji, E; Smith, K J; Roberts, M S; Jensen, M K; LaFleur, J; Nelson, R E

    2014-12-01

    Clostridium difficile infection (CDI) is costly. Current guidelines recommend metronidazole as first-line therapy and vancomycin as an alternative. Recurrence is common. Faecal microbiota transplantation (FMT) is an effective therapy for recurrent CDI (RCDI). This study explores the cost-effectiveness of FMT, vancomycin and metronidazole for initial CDI. We constructed a decision-analytic computer simulation using inputs from published literature to compare FMT with a 10-14-day course of oral metronidazole or vancomycin for initial CDI. Parameters included cure rates (baseline value (range)) for metronidazole (80% (65-85%)), vancomycin (90% (88-92%)) and FMT(91% (83-100%)). Direct costs of metronidazole, vancomycin and FMT, adjusted to 2011 dollars, were $57 ($43-72), $1347 ($1195-1499) and $1086 ($815-1358), respectively. Our effectiveness measure was quality-adjusted life years (QALYs). One-way and probabilistic sensitivity analyses were conducted from the third-party payer perspective. Analysis using baseline values showed that FMT($1669, 0.242 QALYs) dominated (i.e. was less costly and more effective) vancomycin ($1890, 0.241 QALYs). FMT was more costly and more effective than metronidazole ($1167, 0.238 QALYs), yielding an incremental cost-effectiveness ratio (ICER) of $124 964/QALY. One-way sensitivity analyses showed that metronidazole dominated both strategies if its probability of cure were >90%; FMT dominated if it cost <$584. In a probabilistic sensitivity analysis at a willingness-to-pay threshold of $100 000/QALY, metronidazole was favoured in 55% of model iterations; FMT was favoured in 38%. Metronidazole, as the first-line treatment for CDIs, is less costly. FMT and vancomycin are more effective. However, FMT is less likely to be economically favourable, and vancomycin is unlikely to be favourable as first-line therapy when compared with FMT. © 2014 The Authors Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

  9. Research on the optimization of quota design in real estate

    NASA Astrophysics Data System (ADS)

    Sun, Chunling; Ma, Susu; Zhong, Weichao

    2017-11-01

    Quota design is one of the effective methods of cost control in real estate development project and widely used in the current real estate development project to control the engineering construction cost, but quota design have many deficiencies in design process. For this purpose, this paper put forward a method to achieve investment control of real estate development project, which combine quota design and value engineering(VE) at the stage of design. Specifically, it’s an optimizing for the structure of quota design. At first, determine the design limits by investment estimate value, then using VE to carry on initial allocation of design limits and gain the functional target cost, finally, consider the whole life cycle cost (LCC) and operational problem in practical application to finish complex correction for the functional target cost. The improved process can control the project cost more effectively. It not only can control investment in a certain range, but also make the project realize maximum value within investment.

  10. Construction cost forecast model : model documentation and technical notes.

    DOT National Transportation Integrated Search

    2013-05-01

    Construction cost indices are generally estimated with Laspeyres, Paasche, or Fisher indices that allow changes : in the quantities of construction bid items, as well as changes in price to change the cost indices of those items. : These cost indices...

  11. Trends in highway construction costs in Louisiana : technical summary.

    DOT National Transportation Integrated Search

    1999-09-01

    The objectives of this study are to observe past trends in highway construction costs in Louisiana, identify factors that determine these costs, quantify their impact, and establish a model that can be used to predict future construction cost in Loui...

  12. Costs of Occupational Injuries in Construction in the United States

    PubMed Central

    Waehrer, Geetha M.; Dong, Xiuwen S.; Miller, Ted; Haile, Elizabeth; Men, Yurong

    2008-01-01

    This paper presents costs of fatal and non-fatal injuries for the construction industry using 2002 national incidence data from the Bureau of Labor Statistics and a comprehensive cost model that includes direct medical costs, indirect losses in wage and household productivity, as well as an estimate of the quality of life costs due to injury. Costs are presented at the three-digit industry level, by worker characteristics, and by detailed source and event of injury. The total costs of fatal and non-fatal injuries in the construction industry were estimated at $11.5 billion in 2002, 15% of the costs for all private industry. The average cost per case of fatal or nonfatal injury is $27,000 in construction, almost double the per-case cost of $15,000 for all industry in 2002. Five industries accounted for over half the industry’s total fatal and non-fatal injury costs. They were miscellaneous special trade contractors (SIC 179), followed by plumbing, heating and air-conditioning (SIC 171), electrical work (SIC 173), heavy construction except highway (SIC 162), and residential building construction (SIC 152), each with over $1 billion in costs. PMID:17920850

  13. 48 CFR 9904.417 - Cost of money as an element of the cost of capital assets under construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... element of the cost of capital assets under construction. 9904.417 Section 9904.417 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT... of money as an element of the cost of capital assets under construction. ...

  14. The carbohydrate-fat problem: can we construct a healthy diet based on dietary guidelines?

    PubMed

    Drewnowski, Adam

    2015-05-01

    The inclusion of nutrition economics in dietary guidance would help ensure that the Dietary Guidelines for Americans benefit equally all segments of the US population. The present review outlines some novel metrics of food affordability that assess nutrient density of foods and beverages in relation to cost. Socioeconomic disparities in diet quality in the United States are readily apparent. In general, groups of lower socioeconomic status consume cheaper, lower-quality diets and suffer from higher rates of noncommunicable diseases. Nutrient profiling models, initially developed to assess the nutrient density of foods, can be turned into econometric models that assess both calories and nutrients per reference amount and per unit cost. These novel metrics have been used to identify individual foods that were affordable, palatable, culturally acceptable, and nutrient rich. Not all nutrient-rich foods were expensive. In dietary surveys, both local and national, some high-quality diets were associated with relatively low cost. Those population subgroups that successfully adopted dietary guidelines at an unexpectedly low monetary cost were identified as "positive deviants." Constructing a healthy diet based on dietary guidelines can be done, provided that nutrient density of foods, their affordability, as well as taste and social norms are all taken into account. © 2015 American Society for Nutrition.

  15. 48 CFR 36.518 - Work oversight in cost-reimbursement construction contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-reimbursement construction contracts. 36.518 Section 36.518 Federal Acquisition Regulations System FEDERAL... Contract Clauses 36.518 Work oversight in cost-reimbursement construction contracts. The contracting officer shall insert the clause at 52.236-18, Work Oversight in Cost-Reimbursement Construction Contracts...

  16. Space construction system analysis. Part 2: Cost and programmatics

    NASA Technical Reports Server (NTRS)

    Vonflue, F. W.; Cooper, W.

    1980-01-01

    Cost and programmatic elements of the space construction systems analysis study are discussed. The programmatic aspects of the ETVP program define a comprehensive plan for the development of a space platform, the construction system, and the space shuttle operations/logistics requirements. The cost analysis identified significant items of cost on ETVP development, ground, and flight segments, and detailed the items of space construction equipment and operations.

  17. Mobile/Modular BSL-4 Facilities for Meeting Restricted Earth Return Containment Requirements

    NASA Technical Reports Server (NTRS)

    Calaway, M. J.; McCubbin, F. M.; Allton, J. H.; Zeigler, R. A.; Pace, L. F.

    2017-01-01

    NASA robotic sample return missions designated Category V Restricted Earth Return by the NASA Planetary Protection Office require sample containment and biohazard testing in a receiving laboratory as directed by NASA Procedural Requirement (NPR) 8020.12D - ensuring the preservation and protection of Earth and the sample. Currently, NPR 8020.12D classifies Restricted Earth Return for robotic sample return missions from Mars, Europa, and Enceladus with the caveat that future proposed mission locations could be added or restrictions lifted on a case by case basis as scientific knowledge and understanding of biohazards progresses. Since the 1960s, sample containment from an unknown extraterrestrial biohazard have been related to the highest containment standards and protocols known to modern science. Today, Biosafety Level (BSL) 4 standards and protocols are used to study the most dangerous high-risk diseases and unknown biological agents on Earth. Over 30 BSL-4 facilities have been constructed worldwide with 12 residing in the United States; of theses, 8 are operational. In the last two decades, these brick and mortar facilities have cost in the hundreds of millions of dollars dependent on the facility requirements and size. Previous mission concept studies for constructing a NASA sample receiving facility with an integrated BSL-4 quarantine and biohazard testing facility have also been estimated in the hundreds of millions of dollars. As an alternative option, we have recently conducted an initial trade study for constructing a mobile and/or modular sample containment laboratory that would meet all BSL-4 and planetary protection standards and protocols at a faction of the cost. Mobile and modular BSL-2 and 3 facilities have been successfully constructed and deployed world-wide for government testing of pathogens and pharmaceutical production. Our study showed that a modular BSL-4 construction could result in approximately 90% cost reduction when compared to traditional construction methods without compromising the preservation of the sample or Earth.

  18. Highway Cost Index Estimator Tool

    DOT National Transportation Integrated Search

    2017-10-01

    To plan and program highway construction projects, the Texas Department of Transportation requires accurate construction cost data. However, due to the number of, and uncertainty of, variables that affect highway construction costs, estimating future...

  19. Detecting and treating occlusal caries lesions: a cost-effectiveness analysis.

    PubMed

    Schwendicke, F; Stolpe, M; Meyer-Lueckel, H; Paris, S

    2015-02-01

    The health gains and costs resulting from using different caries detection strategies might not only depend on the accuracy of the used method but also the treatment emanating from its use in different populations. We compared combinations of visual-tactile, radiographic, or laser-fluorescence-based detection methods with 1 of 3 treatments (non-, micro-, and invasive treatment) initiated at different cutoffs (treating all or only dentinal lesions) in populations with low or high caries prevalence. A Markov model was constructed to follow an occlusal surface in a permanent molar in an initially 12-y-old male German patient over his lifetime. Prevalence data and transition probabilities were extracted from the literature, while validity parameters of different methods were synthesized or obtained from systematic reviews. Microsimulations were performed to analyze the model, assuming a German health care setting and a mixed public-private payer perspective. Radiographic and fluorescence-based methods led to more overtreatments, especially in populations with low prevalence. For the latter, combining visual-tactile or radiographic detection with microinvasive treatment retained teeth longest (mean 66 y) at lowest costs (329 and 332 Euro, respectively), while combining radiographic or fluorescence-based detections with invasive treatment was the least cost-effective (<60 y, >700 Euro). In populations with high prevalence, combining radiographic detection with microinvasive treatment was most cost-effective (63 y, 528 Euro), while sensitive detection methods combined with invasive treatments were again the least cost-effective (<59 y, >690 Euro). The suitability of detection methods differed significantly between populations, and the cost-effectiveness was greatly influenced by the treatment initiated after lesion detection. The accuracy of a detection method relative to a "gold standard" did not automatically convey into better health or reduced costs. Detection methods should be evaluated not only against their criterion validity but also the long-term effects resulting from their use in different populations. © International & American Associations for Dental Research 2014.

  20. 25 CFR 136.2 - Construction costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Construction costs. 136.2 Section 136.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES FORT HALL INDIAN IRRIGATION PROJECT, IDAHO § 136.2 Construction costs. The program of rehabilitation has now been completed at a cost of $419...

  1. 25 CFR 136.2 - Construction costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Construction costs. 136.2 Section 136.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES FORT HALL INDIAN IRRIGATION PROJECT, IDAHO § 136.2 Construction costs. The program of rehabilitation has now been completed at a cost of $419...

  2. 48 CFR 36.215 - Special procedures for cost-reimbursement contracts for construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... cost-reimbursement contracts for construction. 36.215 Section 36.215 Federal Acquisition Regulations...-reimbursement contracts for construction. Contracting officers may use a cost-reimbursement contract to acquire... limitation on cost-reimbursement contracts). [48 FR 42356, Sept. 19, 1983. Redesignated at 62 FR 272, Jan. 2...

  3. Navy Ford (CVN-78) Class Aircraft Carrier Program: Background and Issues for Congress

    DTIC Science & Technology

    2013-10-22

    states: The CVN 78 is experiencing cost growth due to “first of class” material availability (i.e., valves, actuators ), construction labor...assessment during IOT &E [initial operational test and evaluation]. • The current TEMP [test and evaluation master plan] does not adequately address...developmental testing significantly raises the likelihood of the discovery of platform-level problems during IOT &E. • The Navy plans to deliver CVN-78 in

  4. Costs of medically assisted reproduction treatment at specialized fertility clinics in the Danish public health care system: results from a 5-year follow-up cohort study.

    PubMed

    Christiansen, Terkel; Erb, Karin; Rizvanovic, Amra; Ziebe, Søren; Mikkelsen Englund, Anne L; Hald, Finn; Boivin, Jacky; Schmidt, Lone

    2014-01-01

    To examine the costs to the public health care system of couples in medically assisted reproduction. Longitudinal cohort study of infertile couples initiating medically assisted reproduction treatment. Specialized public fertility clinics in Denmark. Seven hundred and thirty-nine couples having no child at study entry and with data on kind of treatment and live birth (yes/no) for each treatment attempt at the specialized public fertility clinic. Treatment data for medically assisted reproduction attempts conducted at the public fertility clinics were abstracted from medical records. Flow diagrams were drawn for different standard treatment cycles and direct costs at each stage in the flow charts were measured and valued by a bottom-up procedure. Indirect costs were distributed to each treatment cycle on the basis of number of visits as basis. Costs were adjusted to 2012 prices using a constructed medical price index. Live birth, costs. Total costs per live birth in 2012 prices were estimated to 10,755€. Costs per treated couple - irrespective of whether the treatment was terminated by a live birth or not - were estimated at 6607€. Costs per live birth of women <35 years at treatment initiation were 9338€ and 15,040€ for women ≥35 years. The public costs for live births after conception with medically assisted reproduction treatment are relatively modest. The results can be generalized to public fertility treatment in Denmark and to other public treatment settings with similar limitations in numbers of public treatment cycles offered. © 2013 Nordic Federation of Societies of Obstetrics and Gynecology.

  5. Higher mortgages, lower energy bills: The real economics of buying an energy-efficient home

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mills, E.

    1987-02-01

    To measure the actual costs and benefits of buying an energy- efficient home, it is necessary to employ a cash-flow model that accounts for mortgage interest and other charges associated with the incremental costs of conservation measures. The ability to make payments gradually over the term of a mortgage, energy savings, and tax benefits contribute to increased cost effectiveness. Conversely, financial benefits are reduced by interest payments, insurance, taxes, and various fees linked to the (higher) sale price of an energy-efficient home. Accounting for these factors can yield a strikingly different picture from those given by commonly used ''engineering'' indicators,more » such as simple payback time, internal rate of return, or net present value (NPV), which are based solely on incremental costs and energy savings. This analysis uses actual energy savings data and incremental construction costs to evaluate the mortgage cash flow for 79 of the 144 energy-efficient homes constructed in Minnesota under the Energy-Efficient Housing Demonstration Program (EEHDP) initiated in 1980 by the Minnesota Housing Finance Agency. Using typical lending terms and fees, we find that the mean mortgage-NPV derived from the homeowners' real cash flow (including construction and financing costs) is 20% lower than the standard engineering-NPV of the conservation investment: $7981 versus $9810. For eight homes, the mortgage-NPV becomes negative once we account for the various mortgage-related effects. Sensitivities to interest rates, down payment, loan term, and marginal tax rate are included to illustrate the often large impact of alternative assumptions about these parameters. The most dramatic effect occurs when the loan term is reduced from 30 to 15 years and the mortgage NPV falls to -$925. We also evaluate the favorable Federal Home Administration (FHA) terms actually applied to the EEHDP homes. 8 refs., 4 figs., 3 tabs.« less

  6. Solar energy development and application in Japan - An outsiders assessment

    NASA Astrophysics Data System (ADS)

    Knopp, E.

    1982-04-01

    The Sunshine Project was initiated in Japan in 1974 in order to develop energy resources to meet future needs. The solar program consists of three categories; solar home construction, the construction and operation of a 1000 kWe capacity solar thermal power generation plant, and the development of a photovoltaic system with a cost per watt reduced to 1/100 of the present cost. Low interest loans to promote the use of solar systems have resulted in the installation of one million solar collectors. Solar water heaters produced have a 2 sq m collection area and a 200 liters water storage capacity, and an evacuated tube collector with an efficiency of 64% has been developed. Work is being devoted to the production of a 50 times concentrating tracking circular Fresnel-type photovoltaic device, and a solar driven cooling system with a 5.35 kW capacity, which operates with a highly efficient freon vapor expander, has been developed. The problem of collected heat storage is being tested and assessed.

  7. Environmental trade-offs of tunnels vs cut-and-cover subways

    USGS Publications Warehouse

    Walton, M.

    1978-01-01

    Heavy construction projects in cities entail two kinds of cost - internal cost, which can be defined in terms of payments from one set of parties to another, and external cost, which is the cost borne by the community at large as the result of disutilities entailed in construction and operation. Environmental trade-offs involve external costs, which are commonly difficult to measure. Cut-and-cover subway construction probably entails higher external and internal cost than deep tunnel construction in many urban geological environments, but uncertainty concerning the costs and environmental trade-offs of tunneling leads to limited and timid use of tunneling by American designers. Thus uncertainty becomes a major trade-off which works against tunneling. The reverse is true in Sweden after nearly 30 years of subway construction. Econometric methods for measuring external costs exist in principle, but are limited in application. Economic theory based on market pressure does not address the real problem of urban environmental trade-offs. Nevertheless, the problem of uncertainty can be addressed by comparative studies of estimated and as-built costs of cut-and-cover vs tunnel projects and a review of environmental issues associated with such construction. Such a study would benefit the underground construction industry and the design of transportation systems. It would also help solve an aspect of the urban problem. ?? 1978.

  8. Long-term purification efficiency of a wetland constructed to treat runoff from peat extraction.

    PubMed

    Karjalainen, Satu M; Heikkinen, Kaisa; Ihme, Raimo; Kløve, Bjørn

    2016-01-01

    Peat extraction increases the phosphorus, nitrogen, organic matter, suspended solids, and iron concentrations in runoff, resulting in negative effects on downstream water bodies. Wetlands are commonly used as natural cost-effective solutions to mitigate these negative effects. This study analyzed changes in the quality of runoff water from peat extraction areas and the long-term efficiency of constructed wetlands. The results indicate that the quality of runoff water changed after the initial drainage and during peat extraction. Nitrogen leached at high concentrations in the early stages of peat extraction following drainage, whereas the leaching of iron and phosphorus increased after peat extraction from deeper layers. Comparison of water quality and impurities retained immediately after treatment wetland construction and 14 years later showed that the treatment wetland remained functional, with good retention capacity, over a long period.

  9. An analytic-numerical method for the construction of the reference law of operation for a class of mechanical controlled systems

    NASA Astrophysics Data System (ADS)

    Mizhidon, A. D.; Mizhidon, K. A.

    2017-04-01

    An analytic-numerical method for the construction of a reference law of operation for a class of dynamic systems describing vibrations in controlled mechanical systems is proposed. By the reference law of operation of a system, we mean a law of the system motion that satisfies all the requirements for the quality and design features of the system under permanent external disturbances. As disturbances, we consider polyharmonic functions with known amplitudes and frequencies of the harmonics but unknown initial phases. For constructing the reference law of motion, an auxiliary optimal control problem is solved in which the cost function depends on a weighting coefficient. The choice of the weighting coefficient ensures the design of the reference law. Theoretical foundations of the proposed method are given.

  10. Oil and gas pipeline construction cost analysis and developing regression models for cost estimation

    NASA Astrophysics Data System (ADS)

    Thaduri, Ravi Kiran

    In this study, cost data for 180 pipelines and 136 compressor stations have been analyzed. On the basis of the distribution analysis, regression models have been developed. Material, Labor, ROW and miscellaneous costs make up the total cost of a pipeline construction. The pipelines are analyzed based on different pipeline lengths, diameter, location, pipeline volume and year of completion. In a pipeline construction, labor costs dominate the total costs with a share of about 40%. Multiple non-linear regression models are developed to estimate the component costs of pipelines for various cross-sectional areas, lengths and locations. The Compressor stations are analyzed based on the capacity, year of completion and location. Unlike the pipeline costs, material costs dominate the total costs in the construction of compressor station, with an average share of about 50.6%. Land costs have very little influence on the total costs. Similar regression models are developed to estimate the component costs of compressor station for various capacities and locations.

  11. Landslide remediation on Ohio State Route 83 using clean coal combustion by-products

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Payette, R.; Chen, Xi You; Wolfe, W.

    1995-12-31

    The disposal of flue gas desulfurization (FGD) by-products has become a major concern as issues of emission cleansing and landfill costs continue to rise. Laboratory tests conducted at the Ohio State University have shown that dry FGD by-products possess certain engineering properties that have proven desirable in a number of construction uses. As a follow on to the laboratory program, a field investigation into engineering uses of dry FGD wastes was initiated. In the present work, an FGD by-product was used to reconstruct the failed portion of a highway embankment. The construction process and the stability of the repaired embankmentmore » are examined.« less

  12. Natural Cellulose Nanofibers As Sustainable Enhancers in Construction Cement

    PubMed Central

    Jiao, Li; Su, Ming; Chen, Liao; Wang, Yuangang; Zhu, Hongli; Dai, Hongqi

    2016-01-01

    Cement is one of the mostly used construction materials due to its high durability and low cost, but it suffers from brittle fracture and facile crack initiation. This article describes the use of naturally-derived renewable cellulose nanofibers (CNFs) to reinforce cement. The effects of CNFs on the mechanical properties, degree of hydration (DOH), and microstructure of cement pastes have been studied. It is found that an addition of 0.15% by weight of CNFs leads to a 15% and 20% increase in the flexural and compressive strengths of cement paste. The enhancement in mechanical strength is attributed to high DOH and dense microstructure of cement pastes after adding CNFs. PMID:28005917

  13. Prevailing Wage Regulations and School Construction Costs: Evidence from British Columbia.

    ERIC Educational Resources Information Center

    Bilginsoy, Cihan; Philips, Peter

    2000-01-01

    Examines effects of prevailing wage laws on school construction costs, using final cost data from six British Columbia school districts. When controlling for factors such as construction business cycle, number of competitors, and school type, there was no significant unit cost change following the Skill Development and Fair Wage Policy Act.…

  14. Belowground advantages in construction cost facilitate a cryptic plant invasion

    PubMed Central

    Caplan, Joshua S.; Wheaton, Christine N.; Mozdzer, Thomas J.

    2014-01-01

    The energetic cost of plant organ construction is a functional trait that is useful for understanding carbon investment during growth (e.g. the resource acquisition vs. tissue longevity tradeoff), as well as in response to global change factors like elevated CO2 and N. Despite the enormous importance of roots and rhizomes in acquiring soil resources and responding to global change, construction costs have been studied almost exclusively in leaves. We sought to determine how construction costs of aboveground and belowground organs differed between native and introduced lineages of a geographically widely dispersed wetland plant species (Phragmites australis) under varying levels of CO2 and N. We grew plants under ambient and elevated atmospheric CO2, as well as under two levels of soil nitrogen. We determined construction costs for leaves, stems, rhizomes and roots, as well as for whole plants. Across all treatment conditions, the introduced lineage of Phragmites had a 4.3 % lower mean rhizome construction cost than the native. Whole-plant construction costs were also smaller for the introduced lineage, with the largest difference in sample means (3.3 %) occurring under ambient conditions. In having lower rhizome and plant-scale construction costs, the introduced lineage can recoup its investment in tissue construction more quickly, enabling it to generate additional biomass with the same energetic investment. Our results suggest that introduced Phragmites has had an advantageous tissue investment strategy under historic CO2 and N levels, which has facilitated key rhizome processes, such as clonal spread. We recommend that construction costs for multiple organ types be included in future studies of plant carbon economy, especially those investigating global change. PMID:24938305

  15. Social cost in construction projects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Çelik, Tolga, E-mail: tolga.celik@emu.edu.tr; Kamali, Saeed, E-mail: saeedkamali2002@gmail.com; Arayici, Yusuf, E-mail: yusuf.arayici@hku.edu.tr

    Despite the fact that completion of construction projects has a direct positive impact on the growth of national and local economies as well as humans' wellbeing, construction projects, especially in the urban areas, generate serious environmental nuisances for the adjacent residents and have unintentional adverse impacts on their surrounding environment. Construction causative adverse impacts on the neighbouring communities are known as the social costs. This study aims to present a state-of-the-art overview of social costs in construction industry in terms of definition, consideration, classification and quantification. Furthermore, it is aimed to bring the construction social cost phenomenon for the agendamore » of Environmental Impact Assessors.« less

  16. Improvement of the cost-benefit analysis algorithm for high-rise construction projects

    NASA Astrophysics Data System (ADS)

    Gafurov, Andrey; Skotarenko, Oksana; Plotnikov, Vladimir

    2018-03-01

    The specific nature of high-rise investment projects entailing long-term construction, high risks, etc. implies a need to improve the standard algorithm of cost-benefit analysis. An improved algorithm is described in the article. For development of the improved algorithm of cost-benefit analysis for high-rise construction projects, the following methods were used: weighted average cost of capital, dynamic cost-benefit analysis of investment projects, risk mapping, scenario analysis, sensitivity analysis of critical ratios, etc. This comprehensive approach helped to adapt the original algorithm to feasibility objectives in high-rise construction. The authors put together the algorithm of cost-benefit analysis for high-rise construction projects on the basis of risk mapping and sensitivity analysis of critical ratios. The suggested project risk management algorithms greatly expand the standard algorithm of cost-benefit analysis in investment projects, namely: the "Project analysis scenario" flowchart, improving quality and reliability of forecasting reports in investment projects; the main stages of cash flow adjustment based on risk mapping for better cost-benefit project analysis provided the broad range of risks in high-rise construction; analysis of dynamic cost-benefit values considering project sensitivity to crucial variables, improving flexibility in implementation of high-rise projects.

  17. Cost containment and KSC Shuttle facilities or cost containment and aerospace construction

    NASA Technical Reports Server (NTRS)

    Brown, J. A.

    1985-01-01

    This presentation has the objective to show examples of Cost Containment of Aerospace Construction at Kennedy Space Center (KSC), taking into account four major levels of Project Development of the Space Shuttle Facilities. The levels are related to conceptual criteria and site selection, the design of construction and ground support equipment, the construction of facilities and ground support equipment (GSE), and operation and maintenance. Examples of cost containment are discussed. The continued reduction of processing time from landing to launching represents a demonstration of the success of the cost containment methods. Attention is given to the factors which led to the selection of KSC, the use of Cost Engineering, the employment of the Construction Management Concept, and the use of Computer Aided Design/Drafting.

  18. Inhibitors and facilitators of willingness to participate (WTP) in an HIV vaccine trial: construction and initial validation of the Inhibitors and Facilitators of Willingness to Participate Scale (WPS) among women at risk for HIV infection.

    PubMed

    Fincham, Dylan; Kagee, Ashraf; Swartz, Leslie

    2010-04-01

    A psychometric scale assessing inhibitors and facilitators of willingness to participate (WTP) in an HIV vaccine trial has not yet been developed. This study aimed to construct and derive the exploratory factor structure of such a scale. The 35-item Inhibitors and Facilitators of Willingness to Participate Scale (WPS) was developed and administered to a convenience sample of 264 Black females between the ages of 16 and 49 years living in an urban-informal settlement near Cape Town. The subscales of the WPS demonstrated good internal consistency with Cronbach's alpha coefficients ranging between 0.69 and 0.82. A principal components exploratory factor analysis revealed the presence of five latent factors. The factors, which accounted for 45.93% of the variance in WTP, were (1) personal costs, (2) safety and convenience, (3) stigmatisation, (4) personal gains and (5) social approval and trust. Against the backdrop of the study limitations, these results provide initial support for the reliability and construct validity of the WPS among the most eligible trial participants in the Western Cape of South Africa.

  19. Restless Tuneup of High-Fidelity Qubit Gates

    NASA Astrophysics Data System (ADS)

    Rol, M. A.; Bultink, C. C.; O'Brien, T. E.; de Jong, S. R.; Theis, L. S.; Fu, X.; Luthi, F.; Vermeulen, R. F. L.; de Sterke, J. C.; Bruno, A.; Deurloo, D.; Schouten, R. N.; Wilhelm, F. K.; DiCarlo, L.

    2017-04-01

    We present a tuneup protocol for qubit gates with tenfold speedup over traditional methods reliant on qubit initialization by energy relaxation. This speedup is achieved by constructing a cost function for Nelder-Mead optimization from real-time correlation of nondemolition measurements interleaving gate operations without pause. Applying the protocol on a transmon qubit achieves 0.999 average Clifford fidelity in one minute, as independently verified using randomized benchmarking and gate-set tomography. The adjustable sensitivity of the cost function allows the detection of fractional changes in the gate error with a nearly constant signal-to-noise ratio. The restless concept demonstrated can be readily extended to the tuneup of two-qubit gates and measurement operations.

  20. Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States.

    PubMed

    Padula, William V; Larson, Richard A; Dusetzina, Stacie B; Apperley, Jane F; Hehlmann, Rudiger; Baccarani, Michele; Eigendorff, Ekkehard; Guilhot, Joelle; Guilhot, Francois; Hehlmann, Rudiger; Mahon, Francois-Xavier; Martinelli, Giovanni; Mayer, Jiri; Müller, Martin C; Niederwieser, Dietger; Saussele, Susanne; Schiffer, Charles A; Silver, Richard T; Simonsson, Bengt; Conti, Rena M

    2016-07-01

    We analyzed the cost-effectiveness of treating incident chronic myeloid leukemia in chronic phase (CML-CP) with generic imatinib when it becomes available in United States in 2016. In the year following generic entry, imatinib's price is expected to drop 70% to 90%. We hypothesized that initiating treatment with generic imatinib in these patients and then switching to the other tyrosine-kinase inhibitors (TKIs), dasatinib or nilotinib, because of intolerance or lack of effectiveness ("imatinib-first") would be cost-effective compared with the current standard of care: "physicians' choice" of initiating treatment with any one of the three TKIs. We constructed Markov models to compare the five-year cost-effectiveness of imatinib-first vs physician's choice from a US commercial payer perspective, assuming 3% annual discounting ($US 2013). The models' clinical endpoint was five-year overall survival taken from a systematic review of clinical trial results. Per-person spending on incident CML-CP treatment overall care components was estimated using Truven's MarketScan claims data. The main outcome of the models was cost per quality-adjusted life-year (QALY). We interpreted outcomes based on a willingness-to-pay threshold of $100 000/QALY. A panel of European LeukemiaNet experts oversaw the study's conduct. Both strategies met the threshold. Imatinib-first ($277 401, 3.87 QALYs) offered patients a 0.10 decrement in QALYs at a savings of $88 343 over five years to payers compared with physician's choice ($365 744, 3.97 QALYs). The imatinib-first incremental cost-effectiveness ratio was approximately $883 730/QALY. The results were robust to multiple sensitivity analyses. When imatinib loses patent protection and its price declines, its use will be the cost-effective initial treatment strategy for CML-CP. © The Author 2016. Published by Oxford University Press.

  1. Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States

    PubMed Central

    Padula, William V.; Larson, Richard A.; Dusetzina, Stacie B.; Apperley, Jane F.; Hehlmann, Rudiger; Baccarani, Michele; Eigendorff, Ekkehard; Guilhot, Joelle; Guilhot, Francois; Hehlmann, Rudiger; Mahon, Francois-Xavier; Martinelli, Giovanni; Mayer, Jiri; Müller, Martin C.; Niederwieser, Dietger; Saussele, Susanne; Schiffer, Charles A.; Silver, Richard T.; Simonsson, Bengt

    2016-01-01

    Background: We analyzed the cost-effectiveness of treating incident chronic myeloid leukemia in chronic phase (CML-CP) with generic imatinib when it becomes available in United States in 2016. In the year following generic entry, imatinib’s price is expected to drop 70% to 90%. We hypothesized that initiating treatment with generic imatinib in these patients and then switching to the other tyrosine-kinase inhibitors (TKIs), dasatinib or nilotinib, because of intolerance or lack of effectiveness (“imatinib-first”) would be cost-effective compared with the current standard of care: “physicians’ choice” of initiating treatment with any one of the three TKIs. Methods: We constructed Markov models to compare the five-year cost-effectiveness of imatinib-first vs physician’s choice from a US commercial payer perspective, assuming 3% annual discounting ($US 2013). The models’ clinical endpoint was five-year overall survival taken from a systematic review of clinical trial results. Per-person spending on incident CML-CP treatment overall care components was estimated using Truven’s MarketScan claims data. The main outcome of the models was cost per quality-adjusted life-year (QALY). We interpreted outcomes based on a willingness-to-pay threshold of $100 000/QALY. A panel of European LeukemiaNet experts oversaw the study’s conduct. Results: Both strategies met the threshold. Imatinib-first ($277 401, 3.87 QALYs) offered patients a 0.10 decrement in QALYs at a savings of $88 343 over five years to payers compared with physician’s choice ($365 744, 3.97 QALYs). The imatinib-first incremental cost-effectiveness ratio was approximately $883 730/QALY. The results were robust to multiple sensitivity analyses. Conclusion: When imatinib loses patent protection and its price declines, its use will be the cost-effective initial treatment strategy for CML-CP. PMID:26944912

  2. Army ants dynamically adjust living bridges in response to a cost-benefit trade-off.

    PubMed

    Reid, Chris R; Lutz, Matthew J; Powell, Scott; Kao, Albert B; Couzin, Iain D; Garnier, Simon

    2015-12-08

    The ability of individual animals to create functional structures by joining together is rare and confined to the social insects. Army ants (Eciton) form collective assemblages out of their own bodies to perform a variety of functions that benefit the entire colony. Here we examine ‟bridges" of linked individuals that are constructed to span gaps in the colony's foraging trail. How these living structures adjust themselves to varied and changing conditions remains poorly understood. Our field experiments show that the ants continuously modify their bridges, such that these structures lengthen, widen, and change position in response to traffic levels and environmental geometry. Ants initiate bridges where their path deviates from their incoming direction and move the bridges over time to create shortcuts over large gaps. The final position of the structure depended on the intensity of the traffic and the extent of path deviation and was influenced by a cost-benefit trade-off at the colony level, where the benefit of increased foraging trail efficiency was balanced by the cost of removing workers from the foraging pool to form the structure. To examine this trade-off, we quantified the geometric relationship between costs and benefits revealed by our experiments. We then constructed a model to determine the bridge location that maximized foraging rate, which qualitatively matched the observed movement of bridges. Our results highlight how animal self-assemblages can be dynamically modified in response to a group-level cost-benefit trade-off, without any individual unit's having information on global benefits or costs.

  3. Life comparative analysis of energy consumption and CO₂ emissions of different building structural frame types.

    PubMed

    Kim, Sangyong; Moon, Joon-Ho; Shin, Yoonseok; Kim, Gwang-Hee; Seo, Deok-Seok

    2013-01-01

    The objective of this research is to quantitatively measure and compare the environmental load and construction cost of different structural frame types. Construction cost also accounts for the costs of CO₂ emissions of input materials. The choice of structural frame type is a major consideration in construction, as this element represents about 33% of total building construction costs. In this research, four constructed buildings were analyzed, with these having either reinforced concrete (RC) or steel (S) structures. An input-output framework analysis was used to measure energy consumption and CO₂ emissions of input materials for each structural frame type. In addition, the CO₂ emissions cost was measured using the trading price of CO₂ emissions on the International Commodity Exchange. This research revealed that both energy consumption and CO₂ emissions were, on average, 26% lower with the RC structure than with the S structure, and the construction costs (including the CO₂ emissions cost) of the RC structure were about 9.8% lower, compared to the S structure. This research provides insights through which the construction industry will be able to respond to the carbon market, which is expected to continue to grow in the future.

  4. Automated Laser Ultrasonic Testing (ALUT) of Hybrid Arc Welds for Pipeline Construction, #272

    DOT National Transportation Integrated Search

    2009-12-22

    One challenge in developing new gas reserves is the high cost of pipeline construction. Welding costs are a major component of overall construction costs. Industry continues to seek advanced pipeline welding technologies to improve productivity and s...

  5. Visualizing the Invisible: The Construction of Three Low-Cost Schlieren Imaging Systems for the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Gopal, Venkatesh; Klosowiak, Julian L.; Jaeger, Robert; Selimkhanov, Timur; Hartmann, Mitra J. Z.

    2008-01-01

    We describe the construction and operation of three low-cost schlieren imaging systems that can be fabricated using surplus optics and 80/20, an aluminium extrusion based construction system. Each system has a different optical configuration. The low cost and ease of construction makes these systems highly suitable for high-school and…

  6. Design and Implementation of an Intelligent Cost Estimation Model for Decision Support System Software

    DTIC Science & Technology

    1990-09-01

    following two chapters. 28 V. COCOMO MODEL A. OVERVIEW The COCOMO model which stands for COnstructive COst MOdel was developed by Barry Boehm and is...estimation model which uses an expert system to automate the Intermediate COnstructive Cost Estimation MOdel (COCOMO), developed by Barry W. Boehm and...cost estimation model which uses an expert system to automate the Intermediate COnstructive Cost Estimation MOdel (COCOMO), developed by Barry W

  7. Neural-network-based online HJB solution for optimal robust guaranteed cost control of continuous-time uncertain nonlinear systems.

    PubMed

    Liu, Derong; Wang, Ding; Wang, Fei-Yue; Li, Hongliang; Yang, Xiong

    2014-12-01

    In this paper, the infinite horizon optimal robust guaranteed cost control of continuous-time uncertain nonlinear systems is investigated using neural-network-based online solution of Hamilton-Jacobi-Bellman (HJB) equation. By establishing an appropriate bounded function and defining a modified cost function, the optimal robust guaranteed cost control problem is transformed into an optimal control problem. It can be observed that the optimal cost function of the nominal system is nothing but the optimal guaranteed cost of the original uncertain system. A critic neural network is constructed to facilitate the solution of the modified HJB equation corresponding to the nominal system. More importantly, an additional stabilizing term is introduced for helping to verify the stability, which reinforces the updating process of the weight vector and reduces the requirement of an initial stabilizing control. The uniform ultimate boundedness of the closed-loop system is analyzed by using the Lyapunov approach as well. Two simulation examples are provided to verify the effectiveness of the present control approach.

  8. Re-Engineering Alzheimer Clinical Trials: Global Alzheimer's Platform Network.

    PubMed

    Cummings, J; Aisen, P; Barton, R; Bork, J; Doody, R; Dwyer, J; Egan, J C; Feldman, H; Lappin, D; Truyen, L; Salloway, S; Sperling, R; Vradenburg, G

    2016-06-01

    Alzheimer's disease (AD) drug development is costly, time-consuming, and inefficient. Trial site functions, trial design, and patient recruitment for trials all require improvement. The Global Alzheimer Platform (GAP) was initiated in response to these challenges. Four GAP work streams evolved in the US to address different trial challenges: 1) registry-to-cohort web-based recruitment; 2) clinical trial site activation and site network construction (GAP-NET); 3) adaptive proof-of-concept clinical trial design; and 4) finance and fund raising. GAP-NET proposes to establish a standardized network of continuously funded trial sites that are highly qualified to perform trials (with established clinical, biomarker, imaging capability; certified raters; sophisticated management system. GAP-NET will conduct trials for academic and biopharma industry partners using standardized instrument versions and administration. Collaboration with the Innovative Medicines Initiative (IMI) European Prevention of Alzheimer's Disease (EPAD) program, the Canadian Consortium on Neurodegeneration in Aging (CCNA) and other similar international initiatives will allow conduct of global trials. GAP-NET aims to increase trial efficiency and quality, decrease trial redundancy, accelerate cohort development and trial recruitment, and decrease trial costs. The value proposition for sites includes stable funding and uniform training and trial execution; the value to trial sponsors is decreased trial costs, reduced time to execute trials, and enhanced data quality. The value for patients and society is the more rapid availability of new treatments for AD.

  9. Cost estimators for construction of forest roads in the central Appalachians

    Treesearch

    Deborah, A. Layton; Chris O. LeDoux; Curt C. Hassler; Curt C. Hassler

    1992-01-01

    Regression equations were developed for estimating the total cost of road construction in the central Appalachian region. Estimators include methods for predicting total costs for roads constructed using hourly rental methods and roads built on a total-job bid basis. Results show that total-job bid roads cost up to five times as much as roads built than when equipment...

  10. Clinical and health care aspects of respiratory tract disorders in Poland.

    PubMed

    Kanecki, Krzysztof; Zycinska, Katarzyna; Tyszko, Piotr

    2016-01-01

    Respiratory diseases constitute a public health priority worldwide. This is related to the increasing exposure to microorganisms, toxic factors, allergens, drugs and smoking, as the most important factors. Increasing costs of health promotion, prevention, diagnosis and treatment of respiratory tract diseases forces the search for effective strategies in the reduction of costs without making a significant impact of these activities on health results. Chronic obstructive pulmonary disease (COPD) is an example of these diseases with increasing incidence, which has few known modifiable factors and absorbs large medical and social costs. The aim of this study is to present the conception of cost driver analysis that could be useful in constructing a good combination of the EBM-based treatment with cost reduction decisions. Analysis of cost drivers was based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines and Polish recommendations of COPD diagnosis and treatment. The proposition of cost reduction strategy in COPD treatment was based on identification of cost drivers in value chain conception. An increasing incidence and treatment costs of COPD force the search for methods of costs reduction in health care. Identifying, evaluating and modifying the cost drivers with use of the value chain conception could be an effective method in achieving these objectives.

  11. 40 CFR 62.14356 - Compliance schedules and increments of progress.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... POLLUTANTS Federal Plan Requirements for Municipal Solid Waste Landfills That Commenced Construction Prior to...) to initiate on-site construction or initiate on-site installation of emission collection and/or control equipment. (3) Initiate on-site construction: Initiate on-site construction or initiate on-site...

  12. 40 CFR 62.14356 - Compliance schedules and increments of progress.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... POLLUTANTS Federal Plan Requirements for Municipal Solid Waste Landfills That Commenced Construction Prior to...) to initiate on-site construction or initiate on-site installation of emission collection and/or control equipment. (3) Initiate on-site construction: Initiate on-site construction or initiate on-site...

  13. Portable, battery-operated, fluorescence field microscope for the developing world

    NASA Astrophysics Data System (ADS)

    Miller, Andrew R.; Davis, Gregory; Pierce, Mark; Oden, Z. Maria; Richards-Kortum, Rebecca

    2010-02-01

    In many areas of the world, current methods for diagnosis of infectious diseases such as malaria and tuberculosis involve microscopic evaluation of a patient specimen. Advances in fluorescence microscopy can improve diagnostic sensitivity and reduce time and expertise necessary to interpret diagnostic results. However, modern research-grade microscopes are neither available nor appropriate for use in many settings in the developing world. To address this need, we designed, fabricated, and tested a portable, battery-powered, bright field and fluorescence inverted field microscope, optimized for infrastructural constraints of the developing world. We characterized an initial prototype constructed with rapidprototyping techniques, which utilized low-cost, over-the-counter components such as a battery-powered LED flashlight as the light source. The microscope exhibited suitable spatial resolution (0.8 μm) in fluorescence mode to resolve M. tuberculosis bacilli. In bright field mode, malaria parasites were resolvable at 1000x magnification. The initial prototype cost 480 USD and we estimate that the microscope can be manufactured for 230 USD. While future studies are planned to evaluate ease-of-use and reliability, our current system serves as a proof of concept that combined fluorescence and bright field microscopy is possible in a low-cost and portable system.

  14. Evidence-based, multidisciplinary approach to the development of a crotalidae polyvalent antivenin (CroFab) protocol at a university hospital.

    PubMed

    Weant, Kyle A; Johnson, Peter N; Bowers, Rebecca C; Armitstead, John A

    2010-03-01

    Several thousand people are bitten annually by venomous snakes in the US. While the development of ovine Crotalidae polyvalent immune Fab antivenin (FabAV) for Crotalinae snakebite envenomations has greatly changed the way this clinical presentation is treated, multiple issues complicate its use. From patient assessment and evaluation, to medication preparation and administration, to the management of adverse drug reactions, the use of this antidote carries with it multiple points of possible medication variances. The inappropriate use of this agent can result in adverse patient consequences and a significant financial burden for both the hospital and the patient. To describe an evidence-based, multidisciplinary approach that was taken to ensure optimal, safe, and cost-effective treatment of patients with FabAV. Following an analysis of the available literature, a multidisciplinary committee was formed to construct a protocol for use of FabAV. This group included clinical pharmacists, pharmacy administrators, emergency medicine physicians who specialized in wilderness medicine and pharmacy residents. A multidisciplinary FabAV usage protocol was constructed and implemented to ensure appropriate patient evaluation, FabAV use and preparation, monitoring, and follow-up. This protocol was based on the available literature and the expert opinion of the committee. Through the use of a 24-hour in-house pharmacy resident on-call system, clinical pharmacy services were provided to ensure a multidisciplinary approach to the care of these patients emergently. Although limited, initial data show that this approach is effective and may result in substantial cost savings. Initial results from implementation of a protocol for use of FabAV have limited inappropriate use, reduced medication wastage, and decreased costs.

  15. In Brief: Carbon storage initiatives at energy department

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-06-01

    The U.S. Department of Energy (DOE) recently announced several initiatives related to carbon capture. On 12 June, DOE secretary Steven Chu announced an agreement with the FutureGen Alliance that advances construction of the country's first commercial-scale, fully integrated carbon capture and sequestration project in Mattoon, Ill. After estimating costs and doing other assessments, DOE and the alliance will decide in 2010 whether to move forward or discontinue the project. “Developing this technology is critically important for reducing greenhouse gas emissions in the U.S. and around the world,” said Chu. The total anticipated financial contribution for the project is $1.1 billion from DOE and $400-600 million from the alliance.

  16. Age in Relation to Worker Compensation Costs in the Construction Industry

    PubMed Central

    Schwatka, Natalie V.; Butler, Lesley M.; Rosecrance, John C.

    2015-01-01

    Background A better understanding of how workers’ compensation (WC) costs are affected by an aging US workforce is needed, especially for physically demanding industries, such as construction. Methods The relationship between age and injury type on claim costs was evaluated using a database of 107,064 Colorado WC claims filed between 1998 and 2008 among construction workers. Results Mean WC costs increased with increasing age for total cost (P < 0.0001), medical costs (P < 0.0001), and indemnity costs (P < 0.0001). For each one-year increase in age, indemnity, and medical costs increased by 3.5% and 1.1%, respectively. For specific injury types, such as strains and contusions, the association between age and indemnity costs was higher among claimants aged ≥65 compared to claimants aged 18–24. Conclusions Our findings suggest that specific injury types may be partially responsible for the higher indemnity costs among older construction workers, compared with their younger coworkers. PMID:22782837

  17. Age in relation to worker compensation costs in the construction industry.

    PubMed

    Schwatka, Natalie V; Butler, Lesley M; Rosecrance, John C

    2013-03-01

    A better understanding of how workers' compensation (WC) costs are affected by an aging US workforce is needed, especially for physically demanding industries, such as construction. The relationship between age and injury type on claim costs was evaluated using a database of 107,064 Colorado WC claims filed between 1998 and 2008 among construction workers. Mean WC costs increased with increasing age for total cost (P < 0.0001), medical costs (P < 0.0001), and indemnity costs (P < 0.0001). For each one-year increase in age, indemnity, and medical costs increased by 3.5% and 1.1%, respectively. For specific injury types, such as strains and contusions, the association between age and indemnity costs was higher among claimants aged ≥65 compared to claimants aged 18-24. Our findings suggest that specific injury types may be partially responsible for the higher indemnity costs among older construction workers, compared with their younger coworkers. Copyright © 2012 Wiley Periodicals, Inc.

  18. 25 CFR 136.3 - Repayment of construction costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Repayment of construction costs. 136.3 Section 136.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES FORT HALL INDIAN IRRIGATION PROJECT, IDAHO § 136.3 Repayment of construction costs. Under the terms of the contracts, the...

  19. Energy-Smart Choices for Schools. An HVAC Comparison Tool. [CD-ROM].

    ERIC Educational Resources Information Center

    Geothermal Heat Pump Consortium, Inc., Washington, DC.

    A CD ROM program provides comparison construction cost capabilities for heating, ventilation, and air conditioning (HVAC) systems in educational facilities. The program combines multiple types of systems with square footage data on low and high construction cost and school size to automatically calculate HVAC comparative construction costs. (GR)

  20. 48 CFR 52.236-18 - Work Oversight in Cost-Reimbursement Construction Contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-Reimbursement Construction Contracts. 52.236-18 Section 52.236-18 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-18 Work Oversight in Cost-Reimbursement Construction Contracts. As prescribed in 36.518, insert the following clause in solicitations and contracts when cost-reimbursement...

  1. Life Comparative Analysis of Energy Consumption and CO2 Emissions of Different Building Structural Frame Types

    PubMed Central

    Kim, Sangyong; Moon, Joon-Ho; Shin, Yoonseok; Kim, Gwang-Hee; Seo, Deok-Seok

    2013-01-01

    The objective of this research is to quantitatively measure and compare the environmental load and construction cost of different structural frame types. Construction cost also accounts for the costs of CO2 emissions of input materials. The choice of structural frame type is a major consideration in construction, as this element represents about 33% of total building construction costs. In this research, four constructed buildings were analyzed, with these having either reinforced concrete (RC) or steel (S) structures. An input-output framework analysis was used to measure energy consumption and CO2 emissions of input materials for each structural frame type. In addition, the CO2 emissions cost was measured using the trading price of CO2 emissions on the International Commodity Exchange. This research revealed that both energy consumption and CO2 emissions were, on average, 26% lower with the RC structure than with the S structure, and the construction costs (including the CO2 emissions cost) of the RC structure were about 9.8% lower, compared to the S structure. This research provides insights through which the construction industry will be able to respond to the carbon market, which is expected to continue to grow in the future. PMID:24227998

  2. KSC Construction Cost Index

    NASA Technical Reports Server (NTRS)

    Brown, J. A.

    1983-01-01

    Kennedy Space Center cost Index aids in conceptual design cost estimates. Report discusses development of KSC Cost Index since January 1974. Index since January 1974. Index provides management, design engineers, and estimators an up-to-data reference for local labor and material process. Also provides mount and rate of change in these costs used to predict future construction costs.

  3. Auditing of suppliers as the requirement of quality management systems in construction

    NASA Astrophysics Data System (ADS)

    Harasymiuk, Jolanta; Barski, Janusz

    2017-07-01

    The choice of a supplier of construction materials can be important factor of increase or reduction of building works costs. Construction materials present from 40 for 70% of investment task depending on kind of works being provided for realization. There is necessity of estimate of suppliers from the point of view of effectiveness of construction undertaking and necessity from the point of view of conformity of taken operation by executives of construction job and objects within the confines of systems of managements quality being initiated in their organizations. The estimate of suppliers of construction materials and subexecutives of special works is formal requirement in quality management systems, which meets the requirements of the ISO 9001 standard. The aim of this paper is to show possibilities of making use of anaudit for estimate of credibility and reliability of the supplier of construction materials. The article describes kinds of audits, that were carried in quality management systems, with particular taking into consideration audits called as second-site. One characterizes the estimate criterions of qualitative ability and method of choice of the supplier of construction materials. The paper shows also propositions of exemplary questions, that would be estimated in audit process, the way of conducting of this estimate and conditionality of estimate.

  4. 23 CFR 140.907 - Overhead and indirect construction costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... accounting principles; (2) The costs included in the distribution are limited to costs actually incurred by...), part 31, Contract Cost Principles and Procedures, relating to contracts with commercial organizations... 23 Highways 1 2010-04-01 2010-04-01 false Overhead and indirect construction costs. 140.907...

  5. Association between prescription cost sharing and adherence to initial combination antiretroviral therapy in commercially insured antiretroviral-naïve patients with HIV.

    PubMed

    Johnston, Stephen S; Juday, Timothy; Seekins, Daniel; Espindle, Derek; Chu, Bong-Chul

    2012-03-01

    In treatment of human immunodeficiency virus (HIV), high levels of adherence to combination antiretroviral therapy (cART) are required to prevent failure of virologic suppression, development of drug resistance, and permanent loss of therapeutic options. No published research has assessed the association between cART prescription cost sharing and adherence to cART. To analyze the association between cART prescription cost sharing and adherence to initial cART in commercially insured antiretroviral (ARV)-naïve patients with HIV. This retrospective observational cohort study used 2002-2008 data from a large U.S. claims database of more than 56 million commercially insured individuals. Study subjects were patients aged 18 years or older who initiated cART during the period January 1, 2003, to December 31, 2007, had no ARV claims during the 6-month period prior to the initiation date, and had at least 1 ICD-9-CM diagnosis code for HIV infection (042, 795.71, V08) from 12 months before to 12 months after cART initiation. A minimum 12-month period of continuous enrollment after cART initiation was used to construct a patient-quarter repeated measures panel dataset in which each quarter of data that a patient contributed represented an observation. The evaluation period extended from cART initiation until the occurrence of 1 of the following events: addition of an ARV that was not part of the initial cART regimen, 30-day gap in possession of an ARV within the initiated cART regimen, hospitalization of 30 or more days, loss to follow-up due to study end (December 31, 2008), or disenrollment. The study's outcome was quarterly adherence to cART, defined as the number of days within the quarter that a patient possessed all components of the initial cART regimen. Each patient's cART cost-sharing amount was calculated per 30-day supply of the entire cART regimen. Adherence was dichotomized for analysis at the clinically meaningful thresholds of 95% and 78%. The dichotomized adherence outcomes were separately modeled using population-averaged generalized estimating equations (GEEs) with time-varying and time-constant covariates and an exchangeable working correlation structure. Independent variables included cost-sharing amount; sequential quarter number after cART initiation; interaction between cost-sharing amount and sequential quarter number (to capture any changes in the association of cost sharing with adherence that may occur over time after initiation of cART); and patient demographic, clinical, and insurance characteristics. For each sequential quarter after cART initiation, the GEE models were used to generate average predicted probabilities of adherence reaching each threshold (95% and 78%) at cost-sharing levels of $25, $75, and $144, which represented the 25th, 75th, and 90th percentiles of the cost-sharing distribution, respectively. The study sample included 19,199 patient-quarters and 3,731 patients: mean age 41.1 years; 83.2% male; mean (SD) duration of post-index period 5.1 (4.2) quarters; mean (SD) daily cART pill count 3.2 (2.2); mean (median) cost sharing per 30-day supply of the entire cART regimen $67 ($40). In the unadjusted analyses of patient-quarters, mean adherence ranged from 97.2% for cost-sharing levels within the 0-20th percentiles (from $0 to $20 per 30-day cART supply) to 94.0% for cost-sharing levels exceeding the 80th percentile (from $84 to $3,832 per 30-day cART supply). In the adjusted analyses for the second quarter (25th percentile of follow-up duration, n = 3,117 cases still under observation) at the cost-sharing levels of $25, $75, and $144, the predicted probabilities of at least 95% adherence were 0.782, 0.770, and 0.752, respectively, and the predicted probabilities of at least 78% adherence were 0.936, 0.931, and 0.924, respectively. The differences in the predicted probabilities of adherence grew over time. By the seventh quarter (the 75th percentile of follow-up duration, n = 1,096 cases still under observation), the predicted probabilities were 0.773, 0.746, and 0.707 for 95% adherence and 0.933, 0.922, and 0.904 for 78% adherence at cost-sharing levels of $25, $75, and $144, respectively. Increasing cART prescription cost sharing was associated with modestly decreased probability of maintaining clinically meaningful levels of cART adherence.

  6. Solar power satellite status report

    NASA Technical Reports Server (NTRS)

    Davis, H. P.

    1977-01-01

    The development of a solar power satellite program is considered. It is suggested that the solar power satellite is an engineering rather than a science program - that is, that no scientific breakthroughs are required before initiating the project. Available technology is examined, and several key questions are discussed: how efficient is microwave transfer of energy; how feasible is construction in space; and will the advantages of continuous insolation compensate for the costs of building a solar power plant in synchronous orbit 23,000 miles above the earth.

  7. Initiation of small-satellite formations via satellite ejector

    NASA Astrophysics Data System (ADS)

    McMullen, Matthew G

    Small satellites can be constructed at a fraction of the cost of a full-size satellite. One full-size satellite can be replaced with a multitude of small satellites, offering expanded area coverage through formation flight. However, the shortcoming to the smaller size is usually a lack of thrusting capabilities. Furthermore, current designs for small satellite deployment mechanisms are only capable of love deployment velocities (on the order of meters per second). Motivated to address this shortcoming, a conceived satellite ejector would offer a significant orbit change by ejecting the satellite at higher deployment velocities (125-200 m/s). Focusing on the applications of the ejector, it is sought to bridge the gap in prior research by offering a method to initiate formation flight. As a precursor to the initiation, the desired orbit properties to initiate the formation are specified in terms of spacing and velocity change vector. From this, a systematic method is developed to find the relationship among velocity change vector, the desired orbit's orientation, and the spacing required to initiate the formation.

  8. Generalized speed and cost rate in transitionless quantum driving

    NASA Astrophysics Data System (ADS)

    Xu, Zhen-Yu; You, Wen-Long; Dong, Yu-Li; Zhang, Chengjie; Yang, W. L.

    2018-03-01

    Transitionless quantum driving, also known as counterdiabatic driving, is a unique shortcut technique to adiabaticity, enabling a fast-forward evolution to the same target quantum states as those in the adiabatic case. However, as nothing is free, the fast evolution is obtained at the cost of stronger driving fields. Here, given the system initially gets prepared in equilibrium states, we construct relations between the dynamical evolution speed and the cost rate of transitionless quantum driving in two scenarios: one that preserves the transitionless evolution for a single energy eigenstate (individual driving), and the other that maintains all energy eigenstates evolving transitionlessly (collective driving). Remarkably, we find that individual driving may cost as much as collective driving, in contrast to the common belief that individual driving is more economical than collective driving in multilevel systems. We then present a potentially practical proposal to demonstrate the above phenomena in a three-level Landau-Zener model using the electronic spin system of a single nitrogen-vacancy center in diamond.

  9. Cost analysis of a growth guidance system compared with traditional and magnetically controlled growing rods for early-onset scoliosis: a US-based integrated health care delivery system perspective.

    PubMed

    Luhmann, Scott J; McAughey, Eoin M; Ackerman, Stacey J; Bumpass, David B; McCarthy, Richard E

    2018-01-01

    Treating early-onset scoliosis (EOS) with traditional growing rods (TGR) is effective but requires periodic surgical lengthening, risking complications. Alternatives include magnetically controlled growing rods (MCGR) that lengthen noninvasively and the growth guidance system (GGS), which obviate the need for active, distractive lengthenings. Previous studies have reported promising clinical effectiveness for GGS; however the direct medical costs of GGS compared to TGR and MCGR have not yet been explored. To estimate the cost of GGS compared with MCGR and TGR for EOS an economic model was developed from the perspective of a US integrated health care delivery system. Using dual-rod constructs, the model estimated the cumulative costs associated with initial implantation, rod lengthenings (TGR, MCGR), revisions due to device failure, surgical-site infections, device exchange, and final spinal fusion over a 6-year episode of care. Model parameters were from peer-reviewed, published literature. Medicare payments were used as a proxy for provider costs. Costs (2016 US$) were discounted 3% annually. Over a 6-year episode of care, GGS was associated with fewer invasive surgeries per patient than TGR (GGS: 3.4; TGR: 14.4) and lower cumulative costs than MCGR and TGR, saving $25,226 vs TGR. Sensitivity analyses showed that results were sensitive to changes in construct costs, rod breakage rates, months between lengthenings, and TGR lengthening setting of care. Within the model, GGS resulted in fewer invasive surgeries and deep surgical site infections than TGR, and lower cumulative costs per patient than both MCGR and TGR, over a 6-year episode of care. The analysis did not account for family disruption, pain, psychological distress, or compromised health-related quality of life associated with invasive TGR lengthenings, nor for potential patient anxiety surrounding the frequent MCGR lengthenings. Further analyses focusing strictly on current generation technologies should be considered for future research.

  10. Cost analysis of a growth guidance system compared with traditional and magnetically controlled growing rods for early-onset scoliosis: a US-based integrated health care delivery system perspective

    PubMed Central

    Luhmann, Scott J; McAughey, Eoin M; Ackerman, Stacey J; Bumpass, David B; McCarthy, Richard E

    2018-01-01

    Purpose Treating early-onset scoliosis (EOS) with traditional growing rods (TGR) is effective but requires periodic surgical lengthening, risking complications. Alternatives include magnetically controlled growing rods (MCGR) that lengthen noninvasively and the growth guidance system (GGS), which obviate the need for active, distractive lengthenings. Previous studies have reported promising clinical effectiveness for GGS; however the direct medical costs of GGS compared to TGR and MCGR have not yet been explored. Methods To estimate the cost of GGS compared with MCGR and TGR for EOS an economic model was developed from the perspective of a US integrated health care delivery system. Using dual-rod constructs, the model estimated the cumulative costs associated with initial implantation, rod lengthenings (TGR, MCGR), revisions due to device failure, surgical-site infections, device exchange, and final spinal fusion over a 6-year episode of care. Model parameters were from peer-reviewed, published literature. Medicare payments were used as a proxy for provider costs. Costs (2016 US$) were discounted 3% annually. Results Over a 6-year episode of care, GGS was associated with fewer invasive surgeries per patient than TGR (GGS: 3.4; TGR: 14.4) and lower cumulative costs than MCGR and TGR, saving $25,226 vs TGR. Sensitivity analyses showed that results were sensitive to changes in construct costs, rod breakage rates, months between lengthenings, and TGR lengthening setting of care. Conclusion Within the model, GGS resulted in fewer invasive surgeries and deep surgical site infections than TGR, and lower cumulative costs per patient than both MCGR and TGR, over a 6-year episode of care. The analysis did not account for family disruption, pain, psychological distress, or compromised health-related quality of life associated with invasive TGR lengthenings, nor for potential patient anxiety surrounding the frequent MCGR lengthenings. Further analyses focusing strictly on current generation technologies should be considered for future research. PMID:29588607

  11. Lobectomy is a more Cost-Effective Option than Total Thyroidectomy for 1 to 4 cm Papillary Thyroid Carcinoma that do not Possess Clinically Recognizable High-Risk Features.

    PubMed

    Lang, Brian Hung-Hin; Wong, Carlos K H

    2016-10-01

    Although lobectomy is a viable alternative to total thyroidectomy (TT) in low-risk 1 to 4 cm papillary thyroid carcinoma (PTC), lobectomy is associated with higher locoregional recurrence risk and need for completion TT upon discovery of a previously unrecognized histologic high-risk feature (HRF). The present study evaluated long-term cost-effectiveness between lobectomy and TT. Our base case was a hypothetical female cohort aged 40 years with a low-risk 2.5 cm PTC. A Markov decision tree model was constructed to compare cost-effectiveness between lobectomy and TT after 25 years. Patients with an unrecognized HRF (including aggressive histology, microscopic extrathyroidal extension, lymphovascular invasion, positive resection margin, nodal metastasis >5 mm, and multifocality) underwent completion TT after lobectomy. Outcome probabilities, utilities, and costs were estimated from the literature. The threshold for cost-effectiveness was set at US$50,000/quality-adjusted life-year (QALY). Sensitivity and threshold analyses were used to examine model uncertainty. After 25 years, each patient who underwent lobectomy instead of TT cost an extra US$772.08 but gained an additional 0.300 QALY. The incremental cost-effectiveness ratio was US$2577.65/QALY. In the sensitivity analysis, the lobectomy arm began to become cost-effective only after 3 years. Despite varying the reported prevalence of clinically unrecognized HRFs, complication from surgical procedures, annualized recurrence rates, unit cost of surgical procedure or complication, and utility score, lobectomy remained more cost-effective than TT. Despite the higher locoregional recurrence risk and having almost half of the patients undergoing completion TT after lobectomy upon discovery of a previously unrecognized HRF, initial lobectomy was a more cost-effective long-term option than initial TT for 1 to 4 cm PTCs without clinically recognized HRFs.

  12. 24 CFR 92.206 - Eligible project costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Eligible project costs. 92.206....206 Eligible project costs. HOME funds may be used to pay the following eligible costs: (a... following: (1) For new construction projects, costs to meet the new construction standards in § 92.251; (2...

  13. Specifications for the First CSP Building System.

    ERIC Educational Resources Information Center

    Detroit Public Schools, MI.

    The specifications cover the construction of additions to four schools in the Detroit School District. The Construction Systems Program (CSP) was utilized in an attempt to (1) reduce the cost of school construction and provide improved value for the building dollar in terms of function, environment, first cost, and maintenance cost; (2) accelerate…

  14. 48 CFR 31.205-10 - Cost of money.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of the cost of capital assets under construction (48 CFR 9904.417). (b) Cost of money is allowable... measured and added to the cost of capital assets under construction in accordance with 48 CFR 9904.417, as... proposals relating to the contract under which the cost is to be claimed. (c) Actual interest cost in lieu...

  15. 48 CFR 31.205-10 - Cost of money.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of the cost of capital assets under construction (48 CFR 9904.417). (b) Cost of money is allowable... measured and added to the cost of capital assets under construction in accordance with 48 CFR 9904.417, as... proposals relating to the contract under which the cost is to be claimed. (c) Actual interest cost in lieu...

  16. 48 CFR 31.205-10 - Cost of money.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of the cost of capital assets under construction (48 CFR 9904.417). (b) Cost of money is allowable... measured and added to the cost of capital assets under construction in accordance with 48 CFR 9904.417, as... proposals relating to the contract under which the cost is to be claimed. (c) Actual interest cost in lieu...

  17. 48 CFR 31.205-10 - Cost of money.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of the cost of capital assets under construction (48 CFR 9904.417). (b) Cost of money is allowable... measured and added to the cost of capital assets under construction in accordance with 48 CFR 9904.417, as... proposals relating to the contract under which the cost is to be claimed. (c) Actual interest cost in lieu...

  18. 48 CFR 31.205-10 - Cost of money.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of the cost of capital assets under construction (48 CFR 9904.417). (b) Cost of money is allowable... measured and added to the cost of capital assets under construction in accordance with 48 CFR 9904.417, as... proposals relating to the contract under which the cost is to be claimed. (c) Actual interest cost in lieu...

  19. Objective analysis of pseudostress over the Indian Ocean using a direct-minimization approach

    NASA Technical Reports Server (NTRS)

    Legler, David M.; Navon, I. M.; O'Brien, James J.

    1989-01-01

    A technique not previously used in objective analysis of meteorological data is used here to produce monthly average surface pseudostress data over the Indian Ocean. An initial guess field is derived and a cost functional is constructed with five terms: approximation to initial guess, approximation to climatology, a smoothness parameter, and two kinematic terms. The functional is minimized using a conjugate-gradient technique, and the weight for the climatology term controls the overall balance of influence between the climatology and the initial guess. Results from various weight combinations are presented for January and July 1984. Quantitative and qualitative comparisons to the subject analysis are made to find which weight combination provides the best results. The weight on the approximation to climatology is found to balance the influence of the original field and climatology.

  20. 33 CFR 263.15 - Program policies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... undertaken, without regard to time. (b) Applicability of costs to Federal and non-Federal shares. Unless... Corps of Engineers costs for investigations, design, and construction (including costs of supervision... costs of investigations, planning, design and construction, to include those incurred prior to...

  1. 33 CFR 263.15 - Program policies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... undertaken, without regard to time. (b) Applicability of costs to Federal and non-Federal shares. Unless... Corps of Engineers costs for investigations, design, and construction (including costs of supervision... costs of investigations, planning, design and construction, to include those incurred prior to...

  2. National Cost-effectiveness of ASHRAE Standard 90.1-2010 Compared to ASHRAE Standard 90.1-2007

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thornton, Brian; Halverson, Mark A.; Myer, Michael

    Pacific Northwest National Laboratory (PNNL) completed this project for the U.S. Department of Energy’s (DOE’s) Building Energy Codes Program (BECP). DOE’s BECP supports upgrading building energy codes and standards, and the states’ adoption, implementation, and enforcement of upgraded codes and standards. Building energy codes and standards set minimum requirements for energy-efficient design and construction for new and renovated buildings, and impact energy use and greenhouse gas emissions for the life of buildings. Continuous improvement of building energy efficiency is achieved by periodically upgrading energy codes and standards. Ensuring that changes in the code that may alter costs (for building components,more » initial purchase and installation, replacement, maintenance and energy) are cost-effective encourages their acceptance and implementation. ANSI/ASHRAE/IESNA Standard 90.1 is the energy standard for commercial and multi-family residential buildings over three floors.« less

  3. Cost-effectiveness of ASHRAE Standard 90.1-2010 Compared to ASHRAE Standard 90.1-2007

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thornton, Brian A.; Halverson, Mark A.; Myer, Michael

    Pacific Northwest National Laboratory (PNNL) completed this project for the U.S. Department of Energy’s (DOE’s) Building Energy Codes Program (BECP). DOE’s BECP supports upgrading building energy codes and standards, and the states’ adoption, implementation, and enforcement of upgraded codes and standards. Building energy codes and standards set minimum requirements for energy-efficient design and construction for new and renovated buildings, and impact energy use and greenhouse gas emissions for the life of buildings. Continuous improvement of building energy efficiency is achieved by periodically upgrading energy codes and standards. Ensuring that changes in the code that may alter costs (for building components,more » initial purchase and installation, replacement, maintenance and energy) are cost-effective encourages their acceptance and implementation. ANSI/ASHRAE/IESNA Standard 90.1 is the energy standard for commercial and multi-family residential buildings over three floors.« less

  4. PHENIX Work Breakdown Structure. Cost and schedule review copy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-02-01

    The Work Breakdown Structure (WBS) Book begins with this Overview section, which contains the high-level summary cost estimate, the cost profile, and the global construction schedule. The summary cost estimate shows the total US cost and the cost in terms of PHENIX construction funds for building the PHENIX detector. All costs in the WBS book are shown in FY 1993 dollars. Also shown are the institutional and foreign contributions, the level of pre-operations funding, and the cost of deferred items. Pie charts are presented at PHENIX WBS level 1 and 2 that show this information. The PHENIX construction funds aremore » shown broken down to PHENIX WBS level 3 items per fiscal year, and the resulting profile is compared to the RHIC target profile. An accumulated difference of the two profiles is also shown. The PHENIX global construction schedule is presented at the end of the Overview section. Following the Overview are sections for each subsystem. Each subsystem section begins with a summary cost estimate, cost profile, and critical path. The total level 3 cost is broken down into fixed costs (M&S), engineering costs (EDIA) and labor costs. Costs are further broken down in terms of PHENIX construction funds, institutional and foreign contributions, pre-operations funding, and deferred items. Also shown is the contingency at level 3 and the level 4 breakdown of the total cost. The cost profile in fiscal years is shown at level 3. The subsystem summaries are followed by the full cost estimate and schedule sheets for that subsystem. These detailed sheets are typically carried down to level 7 or 8. The cost estimate shows Total, M&S, EDIA, and Labor breakdowns, as well as contingency, for each WBS entry.« less

  5. Restless Tuneup of High-Fidelity Qubit Gates

    NASA Astrophysics Data System (ADS)

    Rol, M. A.; Bultink, C. C.; O'Brien, T. E.; de Jong, S. R.; Theis, L. S.; Fu, X.; Luthi, F.; Vermeulen, R. F. L.; de Sterke, J. C.; Bruno, A.; Deurloo, D.; Schouten, R. N.; Wilhelm, F. K.; Dicarlo, L.

    We present a tuneup protocol for qubit gates with tenfold speedup over traditional methods reliant on qubit initialization by energy relax- ation. This speedup is achieved by constructing a cost function for Nelder-Mead optimization from real-time correlation of non-demolition measurements interleaving gate operations without pause. Applying the protocol on a transmon qubit achieves 0.999 average Clifford fidelity in one minute, as independently verified using randomized benchmarking and gate set tomography. The adjustable sensitivity of the cost function allows detecting fractional reductions in gate error with constant signal- to-noise ratio. The restless concept here demonstrated can be readily extended to the tuneup of two-qubit gates and measurement operations. Research funded by IARPA, an ERC Synergy Grant, Microsoft Research, and the China Scholarship Council.

  6. Advanced space power requirements and techniques. Task 1: Mission projections and requirements. Volume 1: Technical report

    NASA Technical Reports Server (NTRS)

    Wolfe, M. G.

    1978-01-01

    The objectives of this study were to: (1) develop projections of the NASA, DoD, and civil space power requirements for the 1980-1995 time period; (2) identify specific areas of application and space power subsystem type needs for each prospective user; (3) document the supporting and historical base, including relevant cost related measures of performance; and (4) quantify the benefits of specific technology projection advancements. The initial scope of the study included: (1) construction of likely models for NASA, DoD, and civil space systems; (2) generation of a number of future scenarios; (3) extraction of time phased technology requirements based on the scenarios; and (4) cost/benefit analyses of some of the technologies identified.

  7. Contractors perspective for critical factors of cost overrun in highway projects of Sindh, Pakistan

    NASA Astrophysics Data System (ADS)

    Sohu, Samiullah; Abdullah, Abd Halid; Nagapan, Sasitharan; Fattah, Abdul; Ullah, Kaleem; Kumar, Kanesh

    2017-10-01

    Construction industry of Pakistan is creating a number of opportunities in employment as well as plays a role model for economy development of the country. This construction industry has a serious issue of cost overrun in all construction projects especially in construction of highway projects. Cost overrun is a serious and critical issue in construction of highway projects which gives negative impact to construction practitioners because it is not only cross the approved budget but also approved time of the project. The main objective of this study is to find out critical factors causing cost overrun in highway projects of Sindh according to contractors' perspectives. Deep literature review was carried out and a total of 64 factors of cost overrun were identified. To achieve the objective, a questionnaire was designed and distributed among 16 selected respondents who have more than 20 years of experience in construction of highway projects. The results from analysis found that most critical factors of cost overrun in the order of importance include financial and cash flow difficulties faced by contractor, frequent changes in design, changes in price of materials, poor planning by client, change in scope of project, change in specification of materials and delay in taking decisions. This study will assist contractors to narrow down some of the critical factors that would lead to cost overrun, and therefore be prepared with the ways to mitigate these problems in construction of highway projects of Sindh province.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The Work Breakdown Structure (WBS) Book begins with this Overview section, which contains the high-level summary cost estimate, the cost profile, and the global construction schedule. The summary cost estimate shows the total US cost and the cost in terms of PHENIX construction funds for building the PHENIX detector. All costs in the WBS book are shown in FY 1993 dollars. Also shown are the institutional and foreign contributions, the level of pre-operations funding, and the cost of deferred items. Pie charts are presented at PHENIX WBS level 1 and 2 that show this information. The PHENIX construction funds aremore » shown broken down to PHENIX WBS level 3 items per fiscal year, and the resulting profile is compared to the RHIC target profile. An accumulated difference of the two profiles is also shown. The PHENIX global construction schedule is presented at the end of the Overview section. Following the Overview are sections for each subsystem. Each subsystem section begins with a summary cost estimate, cost profile, and critical path. The total level 3 cost is broken down into fixed costs (M&S), engineering costs (EDIA) and labor costs. Costs are further broken down in terms of PHENIX construction funds, institutional and foreign contributions, pre-operations funding, and deferred items. Also shown is the contingency at level 3 and the level 4 breakdown of the total cost. The cost profile in fiscal years is shown at level 3. The subsystem summaries are followed by the full cost estimate and schedule sheets for that subsystem. These detailed sheets are typically carried down to level 7 or 8. The cost estimate Total, M&S, EDIA, and Labor breakdowns, as well as contingency, for each WBS entry.« less

  9. Conceptual Cost Estimating

    NASA Technical Reports Server (NTRS)

    Brown, J. A.

    1983-01-01

    Kennedy Space Center data aid in efficient construction-cost managment. Report discusses development and use of NASA TR-1508, Kennedy Space Center Aerospace Construction price book for preparing conceptual budget, funding cost estimating, and preliminary cost engineering reports. Report based on actual bid prices and Government estimates.

  10. Evaluation of ways and procedures to reduce construction cost and increase competition.

    DOT National Transportation Integrated Search

    2009-01-01

    Construction cost inflation is affecting many state highway agencies including the Texas Department of : Transportation While some of this increase can be attributed to factors such as soaring cost of energy, : reports of large variations in cost of ...

  11. 42 CFR 137.342 - What happens to funds remaining at the conclusion of a cost reimbursement construction project?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What happens to funds remaining at the conclusion of a cost reimbursement construction project? 137.342 Section 137.342 Public Health PUBLIC HEALTH... remaining at the conclusion of a cost reimbursement construction project? All funds, including contingency...

  12. Determinants of mallard and gadwall nesting on constructed islands in North Dakota

    USGS Publications Warehouse

    Shaffer, Terry L.; Dahl, Ann L.; Reynolds, Ronald E.; Baer, Kathy L.; Johnson, Michael A.; Sargeant, Glen A.

    2006-01-01

    Constructed islands with adequate nesting cover provide secure nesting sites for ducks because islands restrict access by mammalian predators. These islands are costly to construct and should be placed in areas that ensure the greatest use by nesting ducks. We studied mallard (Anas platyrhynchos) and gadwall (A. strepera) nesting on constructed islands in North Dakota in 1996 (n = 20) and 1997 (n = 22) to evaluate factors—particularly amount of perennial grass cover in the surrounding landscape and density of breeding pairs—that possibly influence numbers of initiated nests. We also examined effects of island characteristics, such as island vegetation, on numbers of nests. Numbers of mallard and gadwall nests on islands were negatively related to amounts of perennial grass cover in the surrounding uplands. Numbers of mallard nests were positively related to percentages of tall dense cover on islands. We found no effects of breeding-pair density on numbers of nests initiated by either species, possibly because breeding pairs were abundant on all study sites. Percent shrub cover on islands was a better predictor of island use than was percent tall dense cover. Island use by these species increased with island age and distance from mainland shore. Amounts of perennial cover in landscapes should be primary considerations in determining where to build islands. Our data suggest that use of islands by nesting mallards and gadwalls is greatest in landscapes with little perennial grass cover (i.e., high amounts of cropland). Other researchers documented a positive relation between nest success in upland covers and amount of perennial grass cover in the landscape. Therefore, islands constructed in landscapes with little perennial cover should provide greater gains in duck recruitment rates than islands constructed in landscapes with greater amounts of perennial grass cover.

  13. The Cost Effectiveness of Nalmefene for Reduction of Alcohol Consumption in Alcohol-Dependent Patients with High or Very High Drinking-Risk Levels from a UK Societal Perspective.

    PubMed

    Brodtkorb, Thor-Henrik; Bell, Melissa; Irving, Adam H; Laramée, Philippe

    2016-02-01

    To evaluate costs and health outcomes of nalmefene plus psychosocial support, compared with psychosocial intervention alone, for reducing alcohol consumption in alcohol-dependent patients, specifically focusing on societal costs related to productivity losses and crime. A Markov model was constructed to model costs and health outcomes of the treatments over 5 years. Analyses were conducted for nalmefene's licensed population: adults with both alcohol dependence and high or very high drinking-risk levels (DRLs) who do not require immediate detoxification and who have high or very high DRLs after initial assessment. The main outcome measure was cost per quality-adjusted life-year (QALY) gained as assessed from a UK societal perspective. Alcohol-attributable productivity loss, crime and health events occurring at different levels of alcohol consumption were taken from published risk-relation studies. Health-related and societal costs were drawn from public data and the literature. Data on the treatment effect, as well as baseline characteristics of the modelled population and utilities, came from three pivotal phase 3 trials of nalmefene. Nalmefene plus psychosocial support was dominant compared with psychosocial intervention alone, resulting in QALYs gained and reduced societal costs. Sensitivity analyses showed that this conclusion was robust. Nalmefene plus psychosocial support led to per-patient reduced costs of £3324 and £2483, due to reduced productivity losses and crime events, respectively. Nalmefene is cost effective from a UK societal perspective, resulting in greater QALY gains and lower costs compared with psychosocial support alone. Nalmefene demonstrates considerable public benefits by reducing alcohol-attributable productivity losses and crime events in adults with both alcohol dependence and high or very high DRLs who do not require immediate detoxification and who have high or very high DRLs after initial assessment.

  14. 24 CFR 578.47 - New construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true New construction. 578.47 Section 578... construction. (a) Use. Grant funds may be used to: (1) Pay up to 100 percent of the cost of new construction... the floor area by 100 percent or more, and the cost of land associated with that construction, for use...

  15. The prediction of engineering cost for green buildings based on information entropy

    NASA Astrophysics Data System (ADS)

    Liang, Guoqiang; Huang, Jinglian

    2018-03-01

    Green building is the developing trend in the world building industry. Additionally, construction costs are an essential consideration in building constructions. Therefore, it is necessary to investigate the problems of cost prediction in green building. On the basis of analyzing the cost of green building, this paper proposes the forecasting method of actual cost in green building based on information entropy and provides the forecasting working procedure. Using the probability density obtained from statistical data, such as labor costs, material costs, machinery costs, administration costs, profits, risk costs a unit project quotation and etc., situations can be predicted which lead to cost variations between budgeted cost and actual cost in constructions, through estimating the information entropy of budgeted cost and actual cost. The research results of this article have a practical significance in cost control of green building. Additionally, the method proposed in this article can be generalized and applied to a variety of other aspects in building management.

  16. 50 CFR 253.11 - Guarantee policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., except: (1) Vessel construction. The Program will not finance this project cost. The Program will only refinance this project cost for an existing vessel whose previous construction cost has already been financed (or otherwise paid). Refinancing this project cost for a vessel that already exists is not...

  17. Processing Control Information in a Nominal Control Construction: An Eye-Tracking Study.

    PubMed

    Kwon, Nayoung; Sturt, Patrick

    2016-08-01

    In an eye-tracking experiment, we examined the processing of the nominal control construction. Participants' eye-movements were monitored while they read sentences that included either giver control nominals (e.g. promise in Luke's promise to Sophia to photograph himself) or recipient control nominals (e.g. plea in Luke's plea to Sophia to photograph herself). In order to examine both the initial access of control information, and its later use in on-line processing, we combined a manipulation of nominal control with a gender match/mismatch paradigm. Results showed that there was evidence of processing difficulty for giver control sentences (relative to recipient control sentences) at the point where the control dependency was initially created, suggesting that control information was accessed during the early parsing stages. This effect is attributed to a recency preference in the formation of control dependencies; the parser prefers to assign a recent antecedent to PRO. In addition, readers slowed down after reading a reflexive pronoun that mismatched with the gender of the antecedent indicated by the control nominal (e.g. Luke's promise to Sophia to photograph herself). The mismatch cost suggests that control information of the nominal control construction was used to constrain dependency formation involving a controller, PRO and a reflexive, confirming the use of control information in on-line interpretation.

  18. Categorization of potential project cost overrun factors in construction industry

    NASA Astrophysics Data System (ADS)

    Karunakaran, P.; Abdullah, A. H.; Nagapan, S.; Sohu, S.; Kasvar, K. K.

    2018-04-01

    Cost overrun has been severely hit down the economy and reputations for many construction industry around the world. Many project management tools developed to control the budget of a project. However, the cost management is still considered poor as there are many cost overrun issues occurred in the construction industry. Thus, this paper aims to identify and cluster the potential construction project cost overrun factors according to their originating groups using the thematic approach. Basically, through literature review, all the potential factors that may cause cost overrun were screened thoroughly before they were clustered into seven (7) groups of the originating factors, namely project, contract, client, contractor, consultant, labour and external. Each potential factor was explained clearly with some examples based on the Malaysian case studies to illustrate the cost overrun scenario. These findings may aid in the future to highlight on how to mitigate the critical potential factors of cost overrun to reduce or overcome its impact on all the stakeholders involved.

  19. Cost effectiveness of the Oregon quitline "free patch initiative".

    PubMed

    Fellows, Jeffrey L; Bush, Terry; McAfee, Tim; Dickerson, John

    2007-12-01

    We estimated the cost effectiveness of the Oregon tobacco quitline's "free patch initiative" compared to the pre-initiative programme. Using quitline utilisation and cost data from the state, intervention providers and patients, we estimated annual programme use and costs for media promotions and intervention services. We also estimated annual quitline registration calls and the number of quitters and life years saved for the pre-initiative and free patch initiative programmes. Service utilisation and 30-day abstinence at six months were obtained from 959 quitline callers. We compared the cost effectiveness of the free patch initiative (media and intervention costs) to the pre-initiative service offered to insured and uninsured callers. We conducted sensitivity analyses on key programme costs and outcomes by estimating a best case and worst case scenario for each intervention strategy. Compared to the pre-intervention programme, the free patch initiative doubled registered calls, increased quitting fourfold and reduced total costs per quit by $2688. We estimated annual paid media costs were $215 per registered tobacco user for the pre-initiative programme and less than $4 per caller during the free patch initiative. Compared to the pre-initiative programme, incremental quitline promotion and intervention costs for the free patch initiative were $86 (range $22-$353) per life year saved. Compared to the pre-initiative programme, the free patch initiative was a highly cost effective strategy for increasing quitting in the population.

  20. APPLICATION OF THE 3D MODEL OF RAILWAY VIADUCTS TO COST ESTIMATION AND CONSTRUCTION

    NASA Astrophysics Data System (ADS)

    Fujisawa, Yasuo; Yabuki, Nobuyoshi; Igarashi, Zenichi; Yoshino, Hiroyuki

    Three dimensional models of civil engineering structures are only partially used in either design or construction but not both. Research on integration of design, cost estimation and construction by 3Dmodels has not been heard in civil engineering domain yet. Using continuously a 3D product model of a structure from design to construction through estimation should improve the efficiency and decrease the occurrence of mistakes, hence enhancing the quality. In this research, we investigated the current practices of flow from design to construction, particularly focusing on cost estimation. Then, we identified advantages and issues on utilization of 3D design models to estimation and construction by applying 3D models to an actual railway construction project.

  1. Application of Boosting Regression Trees to Preliminary Cost Estimation in Building Construction Projects

    PubMed Central

    2015-01-01

    Among the recent data mining techniques available, the boosting approach has attracted a great deal of attention because of its effective learning algorithm and strong boundaries in terms of its generalization performance. However, the boosting approach has yet to be used in regression problems within the construction domain, including cost estimations, but has been actively utilized in other domains. Therefore, a boosting regression tree (BRT) is applied to cost estimations at the early stage of a construction project to examine the applicability of the boosting approach to a regression problem within the construction domain. To evaluate the performance of the BRT model, its performance was compared with that of a neural network (NN) model, which has been proven to have a high performance in cost estimation domains. The BRT model has shown results similar to those of NN model using 234 actual cost datasets of a building construction project. In addition, the BRT model can provide additional information such as the importance plot and structure model, which can support estimators in comprehending the decision making process. Consequently, the boosting approach has potential applicability in preliminary cost estimations in a building construction project. PMID:26339227

  2. Application of Boosting Regression Trees to Preliminary Cost Estimation in Building Construction Projects.

    PubMed

    Shin, Yoonseok

    2015-01-01

    Among the recent data mining techniques available, the boosting approach has attracted a great deal of attention because of its effective learning algorithm and strong boundaries in terms of its generalization performance. However, the boosting approach has yet to be used in regression problems within the construction domain, including cost estimations, but has been actively utilized in other domains. Therefore, a boosting regression tree (BRT) is applied to cost estimations at the early stage of a construction project to examine the applicability of the boosting approach to a regression problem within the construction domain. To evaluate the performance of the BRT model, its performance was compared with that of a neural network (NN) model, which has been proven to have a high performance in cost estimation domains. The BRT model has shown results similar to those of NN model using 234 actual cost datasets of a building construction project. In addition, the BRT model can provide additional information such as the importance plot and structure model, which can support estimators in comprehending the decision making process. Consequently, the boosting approach has potential applicability in preliminary cost estimations in a building construction project.

  3. Analysis of the Seismic Performance of Isolated Buildings according to Life-Cycle Cost

    PubMed Central

    Dang, Yu; Han, Jian-ping; Li, Yong-tao

    2015-01-01

    This paper proposes an indicator of seismic performance based on life-cycle cost of a building. It is expressed as a ratio of lifetime damage loss to life-cycle cost and determines the seismic performance of isolated buildings. Major factors are considered, including uncertainty in hazard demand and structural capacity, initial costs, and expected loss during earthquakes. Thus, a high indicator value indicates poor building seismic performance. Moreover, random vibration analysis is conducted to measure structural reliability and evaluate the expected loss and life-cycle cost of isolated buildings. The expected loss of an actual, seven-story isolated hospital building is only 37% of that of a fixed-base building. Furthermore, the indicator of the structural seismic performance of the isolated building is much lower in value than that of the structural seismic performance of the fixed-base building. Therefore, isolated buildings are safer and less risky than fixed-base buildings. The indicator based on life-cycle cost assists owners and engineers in making investment decisions in consideration of structural design, construction, and expected loss. It also helps optimize the balance between building reliability and building investment. PMID:25653677

  4. Analysis of the seismic performance of isolated buildings according to life-cycle cost.

    PubMed

    Dang, Yu; Han, Jian-Ping; Li, Yong-Tao

    2015-01-01

    This paper proposes an indicator of seismic performance based on life-cycle cost of a building. It is expressed as a ratio of lifetime damage loss to life-cycle cost and determines the seismic performance of isolated buildings. Major factors are considered, including uncertainty in hazard demand and structural capacity, initial costs, and expected loss during earthquakes. Thus, a high indicator value indicates poor building seismic performance. Moreover, random vibration analysis is conducted to measure structural reliability and evaluate the expected loss and life-cycle cost of isolated buildings. The expected loss of an actual, seven-story isolated hospital building is only 37% of that of a fixed-base building. Furthermore, the indicator of the structural seismic performance of the isolated building is much lower in value than that of the structural seismic performance of the fixed-base building. Therefore, isolated buildings are safer and less risky than fixed-base buildings. The indicator based on life-cycle cost assists owners and engineers in making investment decisions in consideration of structural design, construction, and expected loss. It also helps optimize the balance between building reliability and building investment.

  5. Choice of Hemodialysis Access in Older Adults: A Cost-Effectiveness Analysis.

    PubMed

    Hall, Rasheeda K; Myers, Evan R; Rosas, Sylvia E; O'Hare, Ann M; Colón-Emeric, Cathleen S

    2017-06-07

    Although arteriovenous fistulas have been found to be the most cost-effective form of hemodialysis access, the relative benefits of placing an arteriovenous fistula versus an arteriovenous graft seem to be least certain for older adults and when placed preemptively. However, older adults' life expectancy is heterogeneous, and most patients do not undergo permanent access creation until after dialysis initiation. We evaluated cost-effectiveness of arteriovenous fistula placement after dialysis initiation in older adults as a function of age and life expectancy. Using a hypothetical cohort of patients on incident hemodialysis with central venous catheters, we constructed Markov models of three treatment options: ( 1 ) arteriovenous fistula placement, ( 2 ) arteriovenous graft placement, or ( 3 ) continued catheter use. Costs, utilities, and transitional probabilities were derived from existing literature. Probabilistic sensitivity analyses were performed by age group (65-69, 70-74, 75-79, 80-84, and 85-89 years old) and quartile of life expectancy. Costs, quality-adjusted life-months, and incremental cost-effectiveness ratios were evaluated for up to 5 years. The arteriovenous fistula option was cost effective compared with continued catheter use for all age and life expectancy groups, except for 85-89 year olds in the lowest life expectancy quartile. The arteriovenous fistula option was more cost effective than the arteriovenous graft option for all quartiles of life expectancy among the 65- to 69-year-old age group. For older age groups, differences in cost-effectiveness between the strategies were attenuated, and the arteriovenous fistula option tended to only be cost effective in patients with life expectancy >2 years. For groups for which the arteriovenous fistula option was not cost saving, the cost to gain one quality-adjusted life-month ranged from $2294 to $14,042. Among older adults, the cost-effectiveness of an arteriovenous fistula placed within the first month of dialysis diminishes with increasing age and lower life expectancy and is not the most cost-effective option for those with the most limited life expectancy. Copyright © 2017 by the American Society of Nephrology.

  6. Estimating the value of a Country's built assets: investment-based exposure modelling for global risk assessment

    NASA Astrophysics Data System (ADS)

    Daniell, James; Pomonis, Antonios; Gunasekera, Rashmin; Ishizawa, Oscar; Gaspari, Maria; Lu, Xijie; Aubrecht, Christoph; Ungar, Joachim

    2017-04-01

    In order to quantify disaster risk, there is a demand and need for determining consistent and reliable economic value of built assets at national or sub national level exposed to natural hazards. The value of the built stock in the context of a city or a country is critical for risk modelling applications as it allows for the upper bound in potential losses to be established. Under the World Bank probabilistic disaster risk assessment - Country Disaster Risk Profiles (CDRP) Program and rapid post-disaster loss analyses in CATDAT, key methodologies have been developed that quantify the asset exposure of a country. In this study, we assess the complementary methods determining value of building stock through capital investment data vs aggregated ground up values based on built area and unit cost of construction analyses. Different approaches to modelling exposure around the world, have resulted in estimated values of built assets of some countries differing by order(s) of magnitude. Using the aforementioned methodology of comparing investment data based capital stock and bottom-up unit cost of construction values per square meter of assets; a suitable range of capital stock estimates for built assets have been created. A blind test format was undertaken to compare the two types of approaches from top-down (investment) and bottom-up (construction cost per unit), In many cases, census data, demographic, engineering and construction cost data are key for bottom-up calculations from previous years. Similarly for the top-down investment approach, distributed GFCF (Gross Fixed Capital Formation) data is also required. Over the past few years, numerous studies have been undertaken through the World Bank Caribbean and Central America disaster risk assessment program adopting this methodology initially developed by Gunasekera et al. (2015). The range of values of the building stock is tested for around 15 countries. In addition, three types of costs - Reconstruction cost (building back to the standard required by building codes); Replacement cost (gross capital stock) and Book value (net capital stock - depreciated value of assets) are discussed and the differences in methodologies assessed. We then examine historical costs (reconstruction and replacement) and losses (book value) of natural disasters versus this upper bound of capital stock in various locations to examine the impact of a reasonable capital stock estimate. It is found that some historic loss estimates in publications are not reasonable given the value of assets at the time of the event. This has applications for quantitative disaster risk assessment and development of country disaster risk profiles, economic analyses and benchmarking upper loss limits of built assets damaged due to natural hazards.

  7. 48 CFR 236.271 - Cost-plus-fixed-fee contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Cost-plus-fixed-fee... CONTRACTS Special Aspects of Contracting for Construction 236.271 Cost-plus-fixed-fee contracts. Annual military construction appropriations acts restrict the use of cost-plus-fixed-fee contracts (see 216.306(c...

  8. 23 CFR 635.205 - Finding of cost effectiveness.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Finding of cost effectiveness. 635.205 Section 635.205... CONSTRUCTION AND MAINTENANCE Force Account Construction § 635.205 Finding of cost effectiveness. (a) It may be found cost effective for a State transportation department or county to undertake a federally financed...

  9. Strategies to enhance waste minimization and energy conservation within organizations: a case study from the UK construction sector.

    PubMed

    Jones, Jo; Jackson, Janet; Tudor, Terry; Bates, Margaret

    2012-09-01

    Strategies for enhancing environmental management are a key focus for the government in the UK. Using a manufacturing company from the construction sector as a case study, this paper evaluates selected interventionist techniques, including environmental teams, awareness raising and staff training to improve environmental performance. The study employed a range of methods including questionnaire surveys and audits of energy consumption and generation of waste to examine the outcomes of the selected techniques. The results suggest that initially environmental management was not a focus for either the employees or the company. However, as a result of employing the techniques, the company was able to reduce energy consumption, increase recycling rates and achieve costs savings in excess of £132,000.

  10. Influence of Selected Stakeholders of Construction Investment Projects on the Course of Project

    NASA Astrophysics Data System (ADS)

    Bizon-Górecka, Jadwiga; Górecki, Jarosław

    2017-10-01

    The article presents an entity perspective of the construction investment projects. In a course of the project there are stakeholders who have an indirect influence (e.g. decision-makers in the selection of projects) or a direct influence (e.g. members of the project team). An intuitive opinion about a significant influence of project stakeholders on the project’s course encouraged the authors to undertake a research in this area. The article illustrates the initial phases of the construction project life cycle in a perspective of the entities and, in particular, a role of different stakeholders in making decisions that affect a course of the project. An analysis of the structure of the construction project life cycle makes a substantial involvement of various subjects in the initial phases of the project, i.e. in an initial phase and during a creation of the structures. A key point is to underline the factors of decision-making by the participants of the construction process. It was indicated that the stakeholders have a different impact on the course of the project. In large projects, which have many stakeholders, their role in the implementation of the investment project can vary, depending on the life cycle of the project. They can have positive or negative impacts on achieving the project objectives. The paper presents the results of 100 surveys made among participants of the building processes, executors of the construction projects in the Kuyavian-Pomeranian region. The study was conducted in December 2016 and January 2017. It revealed what is the impact of individual stakeholders of the construction projects on the course of the project. A special attention was paid to a complex relationship between objectives of the project and stakeholders’ goals. A great care to the smallest possible number of risks, which may arise from the different objectives of the project and its stakeholders’ goals, should be focused on the augmentation of correlation of measures of the goals. It is crucial to identify the stakeholders, whereas it is a continuous and quite difficult process. However, when ignoring the impact of specific stakeholders on the implementation of the project, a duration of the project and its costs may increase. A main problem, in establishing a relationship of participants in the construction process, is to take into account the risk of all project stakeholders.

  11. Challenges in the Implementation of Green Home Development in Malaysia: Perspective of Developers

    NASA Astrophysics Data System (ADS)

    Nordin, Rumaizah Mohd; Halim, Ahmad Hafizi Abd; Yunus, Julitta

    2017-12-01

    The construction industry is the main contributor to Malaysian economic growth. One of the main sectors to be highlighted by the Government is housing sector. The population in Malaysia is increasing year by year, thus the demand for houses also rises significantly. However, the fulfilment of basic needs for people normally gives the adverse impacts to the environment. Green home concept is introduced with a purpose to create an acceptable standard of living as well as to preserve nature from destruction, whilst to promote efficiency of energy, water and other natural resources. The study aims to identify current level of awareness and understanding regarding the Green Home concept, together with identifying the challenges that contribute to lack of initiatives in implementation of green home development. This study utilizes the qualitative methodology utilising interviews with housing developers operating in Klang Valley. 20 respondents were interviewed with a semi-structured interview. This study found that level of awareness and understanding on green home concept among construction players and public is low to moderate level. However, it shows improvement in terms of its implementation with all respondents agreed that cost factor is greatest challenge to its implementation. Other challenges identified from the study are low awareness and understanding among construction players and public, low demand for green home, and lack of Government enforcement and initiatives. The study is eventually intended to enhance and improve the sustainable practice in Malaysian’s construction industry.

  12. Implementation of Hospital Computerized Physician Order Entry Systems in a Rural State: Feasibility and Financial Impact

    PubMed Central

    Ohsfeldt, Robert L.; Ward, Marcia M.; Schneider, John E.; Jaana, Mirou; Miller, Thomas R.; Lei, Yang; Wakefield, Douglas S.

    2005-01-01

    Objective The aim of this study was to estimate the costs of implementing computerized physician order entry (CPOE) systems in hospitals in a rural state and to evaluate the financial implications of statewide CPOE implementation. Methods A simulation model was constructed using estimates of initial and ongoing CPOE costs mapped onto all general hospitals in Iowa by bed quantity and current clinical information system (CIS) status. CPOE cost estimates were obtained from a leading CPOE vendor. Current CIS status was determined through mail survey of Iowa hospitals. Patient care revenue and operating cost data published by the Iowa Hospital Association were used to simulate the financial impact of CPOE adoption on hospitals. Results CPOE implementation would dramatically increase operating costs for rural and critical access hospitals in the absence of substantial costs savings associated with improved efficiency or improved patient safety. For urban and rural referral hospitals, the cost impact is less dramatic but still substantial. However, relatively modest benefits in the form of patient care cost savings or revenue enhancement would be sufficient to offset CPOE costs for these larger hospitals. Conclusion Implementation of CPOE in rural or critical access hospitals may depend on net increase in operating costs. Adoption of CPOE may be financially infeasible for these small hospitals in the absence of increases in hospital payments or ongoing subsidies from third parties. PMID:15492033

  13. Safety cost management in construction companies: A proposal classification.

    PubMed

    López-Alonso, M; Ibarrondo-Dávila, M P; Rubio, M C

    2016-06-16

    Estimating health and safety costs in the construction industry presents various difficulties, including the complexity of cost allocation, the inadequacy of data available to managers and the absence of an accounting model designed specifically for safety cost management. Very often, the costs arising from accidents in the workplace are not fully identifiable due to the hidden costs involved. This paper reviews some studies of occupational health and safety cost management and proposes a means of classifying these costs. We conducted an empirical study in which the health and safety costs of 40 construction worksites are estimated. A new classification of the health and safety cost and its categories is proposed: Safety and non-safety costs. The costs of the company's health and safety policy should be included in the information provided by the accounting system, as a starting point for analysis and control. From this perspective, a classification of health and safety costs and its categories is put forward.

  14. Evolutionary cost analysis of valsartan initiation among patients with hypertension: a time series approach.

    PubMed

    Sun, Peter; Chang, Joanne; Zhang, Jie; Kahler, Kristijan H

    2012-01-01

    This study examines the evolutionary impact of valsartan initiation on medical costs. A retrospective time series study design was used with a large, US national commercial claims database for the period of 2004-2008. Hypertensive patients who initiated valsartan between the ages of 18 and 63, and had continuous enrollment for 24-month pre-initiation period and 24-month post-initiation period were selected. Patients' monthly medical costs were calculated based on individual claims. A novel time series model was devised with monthly medical costs as its dependent variables, autoregressive integrated moving average (ARIMA) as its stochastic components, and four indicative variables as its decomposed interventional components. The number of post-initiation months before a cost-offset point was also assessed. Patients (n = 18,269) had mean age of 53 at the initiation date, and 53% of them were female. The most common co-morbid conditions were dyslipidemia (52%), diabetes (24%), and hypertensive complications (17%). The time series model suggests that medical costs were increasing by approximately $10 per month (p < 0.01) before the initiation, and decreasing by approximately $6 per month (p < 0.01) after the initiation. After the 4th post-initiation month, medical costs for patients with the initiation were statistically significantly lower (p < 0.01) than forecasted medical costs for the same patients without the initiation. The study has its limitations in data representativeness, ability to collect unrecorded clinical conditions, treatments, and costs, as well as its generalizability to patients with different characteristics. Commercially insured hypertensive patients experienced monthly medical cost increase before valsartan initiation. Based on our model, the evolutionary impact of the initiation on medical costs included a temporary cost surge, a gradual, consistent, and statistically significant cost decrease, and a cost-offset point around the 4th post-initiation month.

  15. 46 CFR 298.21 - Limits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... customarily be capitalized as Vessel or Shipyard Project construction costs such as designing, engineering...) Cost items include those items usually specified in Vessel or Shipyard Project construction contracts... fees and interest on the Obligations or other borrowings incurred during the construction period...

  16. 46 CFR 298.21 - Limits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... customarily be capitalized as Vessel or Shipyard Project construction costs such as designing, engineering...) Cost items include those items usually specified in Vessel or Shipyard Project construction contracts... fees and interest on the Obligations or other borrowings incurred during the construction period...

  17. 46 CFR 298.21 - Limits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... customarily be capitalized as Vessel or Shipyard Project construction costs such as designing, engineering...) Cost items include those items usually specified in Vessel or Shipyard Project construction contracts... fees and interest on the Obligations or other borrowings incurred during the construction period...

  18. A review of BIM (Building Information Modeling) implementation in Indonesia construction industry

    NASA Astrophysics Data System (ADS)

    Suryadinata Telaga, Abdi

    2018-05-01

    Construction projects in Indonesia have been growing rapidly in the last three years. Therefore, construction management is very important to ensure completion of construction projects are within schedule and budget. Utilization of building information modeling (BIM) can increase the efficiency of a construction project. However, the implementation of BIM in Indonesia is still not known. This paper is intended to review the implementation of BIM in Indonesia through literature analysis. To find BIM articles in Indonesia, Firstly, searching was limited to English articles published in reputed journals or conferences. However the results were limited, then the search was expanded to the article using Indonesian languages that published in journal and conference. Based on the number of articles, the results showed that BIM research in Indonesia is still in a dearth. Furthermore, BIM study cases were conducted in a limited location and within a small population. Nevertheless, the literature shared the conclusion that BIM can increase project efficiency, but the implementation was hindered by high initial investment cost, inadequate human resources, small demand, and technology resistant. The research contributes to providing a current reported level of BIM implementation in Indonesia. In the future research to study of BIM implementation comprehensively in Indonesia is eminent.

  19. Costing the cascade: estimating the cost of increased obstetric intervention in childbirth using population data.

    PubMed

    Tracy, Sally K; Tracy, Mark B

    2003-08-01

    To estimate the cost of "the cascade" of obstetric interventions introduced during labour for low risk women. A cost formula derived from population data. New South Wales, Australia. All 171,157 women having a live baby during 1996 and 1997. Four groups of interventions that occur during labour were identified. A cost model was constructed using the known age-adjusted rates for low risk women having one of three birth outcomes following these pre-specified interventions. Costs were based on statewide averages for the cost of labour and birth in hospital. The outcome measure is an "average cost unit per woman" for low risk women, predicted by the level of intervention during labour. Obstetric care is classified as either private obstetric care in a private or public hospital, or routine public hospital care. The relative cost of birth increased by up to 50% for low risk primiparous women and up to 36% for low risk multiparous women as labour interventions accumulated. An epidural was associated with a sharp increase in cost of up to 32% for some primiparous low risk women, and up to 36% for some multiparous low risk women. Private obstetric care increased the overall relative cost by 9% for primiparous low risk women and 4% for multiparous low risk women. The initiation of a cascade of obstetric interventions during labour for low risk women is costly to the health system. Private obstetric care adds further to the cost of care for low risk women.

  20. Red-Carpet Treatment.

    ERIC Educational Resources Information Center

    Agron, Joe

    2001-01-01

    Presents comparative data on college and university residence hall construction projects, including construction costs, size, numbers of students, and cost per square foot. Also provides comparative housing cost data over the past decade and identifies types of amenities being added to dormitories. (GR)

  1. Risk Analysis of Underestimate Cost Offer to The Project Quality in Aceh Province

    NASA Astrophysics Data System (ADS)

    Rani, Hafnidar A.

    2016-11-01

    The possibility of errors in the process of offer price determination could be enormous, so it can affect the possibility of project underestimate cost which can impact and reduce the profit if being implementing. Government Equipment/Service Procurement Policy Institution (LKPP) assesses that the practices of cheaper price in the government equipment/service procurement are still highly found and can be potential to decrease the project quality. This study aimed to analyze the most dominant factors happened in underestimate cost offer practice, to analyze the relationship of underestimate cost offer risk factors to road construction project quality in Aceh Province and to analyze the most potential factors of underestimate cost offer risk affecting road construction project quality in Aceh Province. Road construction projects observed the projects which have been implemented in Aceh Province since 2013 - 2015. This study conducted by interviewing Government Budget Authority (KPA), and distributing the questionnaire to the road construction contractors with the qualification of K1, K2, K3, M1, M2 and B1. Based on the data from Construction Service Development Institution (LPJK) of Aceh Province on 2016, the populations obtained are 2,717 constructors. By using Slovin Equation, the research samples obtained are 97 contractors. The most dominant factors in underestimate cost offer risk of the road construction projects in Aceh Province is Contingency Cost Factor which the mean is 4.374.

  2. 48 CFR 9904.417-60 - Illustrations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... should be added to the construction-in-progress account in recognition of the cost of money related to... should be added to the construction-in-progress account in recognition of the cost of money while under... the costs were incurred at a fairly uniform rate throughout the period. Because of the pattern of cost...

  3. 75 FR 68669 - Loan Guaranty: Assistance to Eligible Individuals in Acquiring Specially Adapted Housing; Cost-of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... Specially Adapted Housing; Cost-of-Construction Index AGENCY: Department of Veterans Affairs. ACTION: Notice... SAH assistance annually based on a residential home cost-of-construction index. The Secretary uses the Turner Building Cost Index for this purpose. During the most recent calendar year for which the Turner...

  4. Literature review of methods to determine road user costs in construction zones

    DOT National Transportation Integrated Search

    1997-01-01

    As freeway construction increases with the need to expand, repair and maintain the existing infrastructure, the desire to quantify the inconvenience or delay costs to the user of the freeway undergoing construction has increased and become neccessary...

  5. Cost Analysis of Establishing a Relationship Between a Surgical Program in the US and Vietnam

    PubMed Central

    Chu, Quyen D.; Nguyen, Thu; Nguyen, Phuong; Ho, Hung S.

    2012-01-01

    “Twinning” refers to a constructive partnership between hospitals in developed and developing nations. Such an effort may contribute immensely to capacity building for the developing nation, but one of the reasons given for the lack of sustainability is cost. We share a detailed operating cost analysis of our recent experience with an institution in Vietnam. We were awarded a 1-year $54,000 grant from the Vietnam Education Foundation (VEF) to conduct a live tele-video conferencing course on the “Fundamentals of Clinical Surgery” with Thai Binh Medical University (TBMU). In-country lectures as well as an assessment of the needs at TBMU were performed. Total financial assistance and expenditures were tabulated to assess up-front infrastructure investment and annual cost required to sustain the program. The total amount of direct money ($66,686) and in-kind services ($70,276) was $136,962. The initial infrastructure cost was $41,085, which represented 62% of the direct money received. The annual cost to sustain the program was approximately $11,948. We concluded that the annual cost to maintain a “twinning” program was relatively low, and the efforts to sustain a “twinning” program were financially feasible and worthwhile endeavors. “Twinning” should be a critical part of the surgical humanitarian volunteerism effort. PMID:23102082

  6. Cost analysis of establishing a relationship between a surgical program in the US and Vietnam.

    PubMed

    Chu, Quyen D; Nguyen, Thu; Nguyen, Phuong; Ho, Hung S

    2012-01-01

    "Twinning" refers to a constructive partnership between hospitals in developed and developing nations. Such an effort may contribute immensely to capacity building for the developing nation, but one of the reasons given for the lack of sustainability is cost. We share a detailed operating cost analysis of our recent experience with an institution in Vietnam. We were awarded a 1-year $54,000 grant from the Vietnam Education Foundation (VEF) to conduct a live tele-video conferencing course on the "Fundamentals of Clinical Surgery" with Thai Binh Medical University (TBMU). In-country lectures as well as an assessment of the needs at TBMU were performed. Total financial assistance and expenditures were tabulated to assess up-front infrastructure investment and annual cost required to sustain the program. The total amount of direct money ($66,686) and in-kind services ($70,276) was $136,962. The initial infrastructure cost was $41,085, which represented 62% of the direct money received. The annual cost to sustain the program was approximately $11,948. We concluded that the annual cost to maintain a "twinning" program was relatively low, and the efforts to sustain a "twinning" program were financially feasible and worthwhile endeavors. "Twinning" should be a critical part of the surgical humanitarian volunteerism effort.

  7. SEM-PLS Analysis of Inhibiting Factors of Cost Performance for Large Construction Projects in Malaysia: Perspective of Clients and Consultants

    PubMed Central

    Memon, Aftab Hameed; Rahman, Ismail Abdul

    2014-01-01

    This study uncovered inhibiting factors to cost performance in large construction projects of Malaysia. Questionnaire survey was conducted among clients and consultants involved in large construction projects. In the questionnaire, a total of 35 inhibiting factors grouped in 7 categories were presented to the respondents for rating significant level of each factor. A total of 300 questionnaire forms were distributed. Only 144 completed sets were received and analysed using advanced multivariate statistical software of Structural Equation Modelling (SmartPLS v2). The analysis involved three iteration processes where several of the factors were deleted in order to make the model acceptable. The result of the analysis found that R 2 value of the model is 0.422 which indicates that the developed model has a substantial impact on cost performance. Based on the final form of the model, contractor's site management category is the most prominent in exhibiting effect on cost performance of large construction projects. This finding is validated using advanced techniques of power analysis. This vigorous multivariate analysis has explicitly found the significant category which consists of several causative factors to poor cost performance in large construction projects. This will benefit all parties involved in construction projects for controlling cost overrun. PMID:24693227

  8. SEM-PLS analysis of inhibiting factors of cost performance for large construction projects in Malaysia: perspective of clients and consultants.

    PubMed

    Memon, Aftab Hameed; Rahman, Ismail Abdul

    2014-01-01

    This study uncovered inhibiting factors to cost performance in large construction projects of Malaysia. Questionnaire survey was conducted among clients and consultants involved in large construction projects. In the questionnaire, a total of 35 inhibiting factors grouped in 7 categories were presented to the respondents for rating significant level of each factor. A total of 300 questionnaire forms were distributed. Only 144 completed sets were received and analysed using advanced multivariate statistical software of Structural Equation Modelling (SmartPLS v2). The analysis involved three iteration processes where several of the factors were deleted in order to make the model acceptable. The result of the analysis found that R(2) value of the model is 0.422 which indicates that the developed model has a substantial impact on cost performance. Based on the final form of the model, contractor's site management category is the most prominent in exhibiting effect on cost performance of large construction projects. This finding is validated using advanced techniques of power analysis. This vigorous multivariate analysis has explicitly found the significant category which consists of several causative factors to poor cost performance in large construction projects. This will benefit all parties involved in construction projects for controlling cost overrun.

  9. Encapsulation task of the low-cost silicon solar array project. Investigation of test methods, material properties, and processes for solar cell encapsulants

    NASA Technical Reports Server (NTRS)

    Willis, P. B.; Baum, B.; White, R. A.

    1978-01-01

    The results of an investigation of solar module encapsulation systems applicable to the Low-Cost Solar Array Project 1986 cost and performance goals are presented. Six basic construction elements were identified and their specific uses in module construction defined. A uniform coating basis was established for each element. The survey results were also useful in revealing price ranges for classes of materials and estimating the cost allocation for each element within the encapsulating cost goal. The six construction elements were considered to be substrates, superstrates, pottants, adhesives, outer covers and back covers.

  10. Workers' compensation costs among construction workers: a robust regression analysis.

    PubMed

    Friedman, Lee S; Forst, Linda S

    2009-11-01

    Workers' compensation data are an important source for evaluating costs associated with construction injuries. We describe the characteristics of injured construction workers filing claims in Illinois between 2000 and 2005 and the factors associated with compensation costs using a robust regression model. In the final multivariable model, the cumulative percent temporary and permanent disability-measures of severity of injury-explained 38.7% of the variance of cost. Attorney costs explained only 0.3% of the variance of the dependent variable. The model used in this study clearly indicated that percent disability was the most important determinant of cost, although the method and uniformity of percent impairment allocation could be better elucidated. There is a need to integrate analytical methods that are suitable for skewed data when analyzing claim costs.

  11. Case Study for the ARRA-funded Ground Source Heat Pump Demonstration at Denver Museum of Nature & Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Im, Piljae; Liu, Xiaobing

    High initial costs and lack of public awareness of ground-source heat pump (GSHP) technology are the two major barriers preventing rapid deployment of this energy-saving technology in the United States. Under the American Recovery and Reinvestment Act (ARRA), 26 GSHP projects were competitively selected and carried out to demonstrate the benefits of GSHP systems and innovative technologies for cost reduction and/or performance improvement. This report highlights the findings of a case study of one such GSHP demonstration projects that uses a recycled water heat pump (RWHP) system installed at the Denver Museum of Nature & Science in Denver, Colorado. Themore » RWHP system uses recycled water from the city’s water system as the heat sink and source for a modular water-to-water heat pump (WWHP). This case study was conducted based on the available measured performance data from December 2014 through August 2015, utility bills of the building in 2014 and 2015, construction drawings, maintenance records, personal communications, and construction costs. The annual energy consumption of the RWHP system was calculated based on the available measured data and other related information. It was compared with the performance of a baseline scenario— a conventional VAV system using a water-cooled chiller and a natural gas fired boiler, both of which have the minimum energy efficiencies allowed by ASHRAE 90.1-2010. The comparison was made to determine energy savings, operating cost savings, and CO2 emission reductions achieved by the RWHP system. A cost analysis was performed to evaluate the simple payback of the RWHP system. Summarized below are the results of the performance analysis, the learned lessons, and recommended improvement in the operation of the RWHP system.« less

  12. A Semantics-Based Approach to Construction Cost Estimating

    ERIC Educational Resources Information Center

    Niknam, Mehrdad

    2015-01-01

    A construction project requires collaboration of different organizations such as owner, designer, contractor, and resource suppliers. These organizations need to exchange information to improve their teamwork. Understanding the information created in other organizations requires specialized human resources. Construction cost estimating is one of…

  13. An outdoor test facility for the large-scale production of microalgae

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, D.A.; Weissman, J.; Goebel, R.

    The goal of the US Department of EnergySolar Energy Research Institute's Aquatic Species Program is to develop the technology base to produce liquid fuels from microalgae. This technology is being initially developed for the desert Southwest. As part of this program an outdoor test facility has been designed and constructed in Roswell, New Mexico. The site has a large existing infrastructure, a suitable climate, and abundant saline groundwater. This facility will be used to evaluate productivity of microalgae strains and conduct large-scale experiments to increase biomass productivity while decreasing production costs. Six 3-m/sup 2/ fiberglass raceways were constructed. Several microalgaemore » strains were screened for growth, one of which had a short-term productivity rate of greater than 50 g dry wt m/sup /minus/2/ d/sup /minus/1/. Two large-scale, 0.1-ha raceways have also been built. These are being used to evaluate the performance trade-offs between low-cost earthen liners and higher cost plastic liners. A series of hydraulic measurements is also being carried out to evaluate future improved pond designs. Future plans include a 0.5-ha pond, which will be built in approximately 2 years to test a scaled-up system. This unique facility will be available to other researchers and industry for studies on microalgae productivity. 6 refs., 9 figs., 1 tab.« less

  14. The construction and operation of a low-cost poultry waste digester.

    PubMed

    Steinsberger, S C; Shih, J C

    1984-05-01

    A simple and low-cost poultry waste digester (PWD) was constructed to treat the waste from 4000 caged laying hens on University Research Unit No. 2 at North Carolina State University. The system was built basically of a plastic lining with insulation, a heating system, a hot-water tank, and other metering equipment. It was operated at 50 degrees C and pH 7.5-8.0. The initiation of methane production was achieved using the indigenous microflora in the poultry waste. At an optimal loading rate (7.5 kg volatile solids/m(3) day), the PWD produced biogas (55% methane) at a rate of 4.0 m(3)/m(3) day. The PWD was biologically stable and able to tolerate temporary overloads and shutdowns. A higher loading rate failed to maintain a high gas production rate and caused drops in methane content and pH value. Under optimal conditions, a positive energy balance was demonstrated with a net surplus of 50.6% of the gross energy. For methane production, the PWD system was proved to be technically feasible. The simple design and inexpensive materials used for this model could significantly reduce the cost of digestion compared to more conventional systems. More studies are needed to determine the durability, the required maintenance of the system, and the most economical method of biogas and solid residue utilization.

  15. Assessing the costs attributed to project delay during project pre-construction stages

    DOT National Transportation Integrated Search

    2016-03-01

    This project for the Texas Department of Transportation (TxDOT) developed a simple but sound : methodology for estimating the cost of delaying most types of highway projects. Researchers considered the : cost of delays during the pre-construction pha...

  16. Assessing the costs attributed to project delay during project pre-construction stages.

    DOT National Transportation Integrated Search

    2016-03-01

    This project for the Texas Department of Transportation (TxDOT) developed a simple but sound : methodology for estimating the cost of delaying most types of highway projects. Researchers considered the : cost of delays during the pre-construction pha...

  17. 36 CFR 223.82 - Contents of advertisement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sale which includes specified road construction with total estimated construction costs of $50,000 or more, the advertisement shall also include: (1) The total estimated construction cost of the permanent roads. (2) A statement extending to small business concerns qualified for preferential bidding on timber...

  18. Social cost impact assessment of pipeline infrastructure projects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matthews, John C., E-mail: matthewsj@battelle.org; Allouche, Erez N., E-mail: allouche@latech.edu; Sterling, Raymond L., E-mail: sterling@latech.edu

    A key advantage of trenchless construction methods compared with traditional open-cut methods is their ability to install or rehabilitate underground utility systems with limited disruption to the surrounding built and natural environments. The equivalent monetary values of these disruptions are commonly called social costs. Social costs are often ignored by engineers or project managers during project planning and design phases, partially because they cannot be calculated using standard estimating methods. In recent years some approaches for estimating social costs were presented. Nevertheless, the cost data needed for validation of these estimating methods is lacking. Development of such social cost databasesmore » can be accomplished by compiling relevant information reported in various case histories. This paper identifies eight most important social cost categories, presents mathematical methods for calculating them, and summarizes the social cost impacts for two pipeline construction projects. The case histories are analyzed in order to identify trends for the various social cost categories. The effectiveness of the methods used to estimate these values is also discussed. These findings are valuable for pipeline infrastructure engineers making renewal technology selection decisions by providing a more accurate process for the assessment of social costs and impacts. - Highlights: • Identified the eight most important social cost factors for pipeline construction • Presented mathematical methods for calculating those social cost factors • Summarized social cost impacts for two pipeline construction projects • Analyzed those projects to identify trends for the social cost factors.« less

  19. Investigation on the Factors Influencing Construction Time and Cost Overrun for High-Rise Building Projects In Penang

    NASA Astrophysics Data System (ADS)

    Nor Haslinda, A.; Xian, T. Wei; Norfarahayu, K.; Muhamad Hanafi, R.; Fikri, H. Muhammad

    2018-04-01

    Time and cost overruns have become one prominent issue for most construction projects around the world. Project costing and timeframe extension had been causing a lot of wastage and loss of opportunity for many parties involved. Therefore, this research was carried out to investigate the factors influencing time and cost overruns for high-rise construction projects in Penang, Malaysia. A set of questionnaires survey was distributed to the project managers who had been or currently involved in the high-rise building projects in Penang to get their input and perceptions for each factor identified as well as its frequency of occurrence. In order to rank all the factors gathered, the mean index of the most distinguishing factors and its frequency of occurrence were multiplied to get the severity index. The results revealed that for time overrun, the most predominant causes were due to design changes, inadequate planning and scheduling and poor labor productivity. Meanwhile, the predominant causes of cost overrun were poor pre-construction budget and material cost planning, inaccurate quantity take-off and materials cost increased by inflation. The significance of establishing the issues related to time and cost overruns for the high-rise building construction project is to provide a greater insight and understanding on the causes of delays, particularly among the main project players: contractors, client, and consultants.

  20. Navy DDG-51 and DDG-1000 Destroyer Programs: Background and Issues for Congress

    DTIC Science & Technology

    2012-03-02

    challenging ship redesign as well as a new power and cooling architecture coupled with the challenges to construct such a dense ship, will make...costs. Our prior work has shown that construction of lead ships is challenging , the risk of cost growth is high, and having sufficient construction...not include a thorough trade-off analysis that would compare the relative costs and benefits of different solutions under consideration or provide

  1. Solar power satellite. System definition study. Part 1, volume 3: Construction, transportation and cost analyses

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Concepts developed for both LEO and GEO construction of photovoltaic and thermal engine satellites are analyzed. Topics discussed include: satellite construction; crew scheduling; crew jobs and organizations; operator productivity rating; constructability rating; transportation systems for cargo launch, refueling operations, personnel transport, and orbit transfer; collision analysis, cost analysis, and radiation evironment and effects.

  2. 25 CFR 900.134 - At the end of a self-determination construction contract, what happens to savings on a cost...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false At the end of a self-determination construction contract... SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.134 At the end of a self-determination construction contract, what happens to savings on a cost...

  3. 25 CFR 900.134 - At the end of a self-determination construction contract, what happens to savings on a cost...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false At the end of a self-determination construction contract... SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.134 At the end of a self-determination construction contract, what happens to savings on a cost...

  4. 25 CFR 900.134 - At the end of a self-determination construction contract, what happens to savings on a cost...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false At the end of a self-determination construction contract... SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.134 At the end of a self-determination construction contract, what happens to savings on a cost...

  5. 25 CFR 900.134 - At the end of a self-determination construction contract, what happens to savings on a cost...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false At the end of a self-determination construction contract... SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.134 At the end of a self-determination construction contract, what happens to savings on a cost...

  6. 25 CFR 900.134 - At the end of a self-determination construction contract, what happens to savings on a cost...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false At the end of a self-determination construction contract... SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.134 At the end of a self-determination construction contract, what happens to savings on a cost...

  7. CNCC Craig Campus Geothermal Project: 82-well closed loop GHP well field to provide geothermal energy as a common utilitiy for a new community college campus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chevron Energy Solutions; Matt Rush; Scott Shulda

    Colorado Northwestern Community College (CNCC) is working collaboratively with recipient vendor Chevron Energy Solutions, an energy services company (ESCO), to develop an innovative GHP project at the new CNCC Campus constructed in 2010/2011 in Craig, Colorado. The purpose of the CNCC Craig Campus Geothermal Program scope was to utilize an energy performance contracting approach to develop a geothermal system with a shared closed-loop field providing geothermal energy to each building's GHP mechanical system. Additional benefits to the project include promoting good jobs and clean energy while reducing operating costs for the college. The project has demonstrated that GHP technology ismore » viable for new construction using the energy performance contracting model. The project also enabled the project team to evaluate several options to give the College a best value proposition for not only the initial design and construction costs but build high performance facilities that will save the College for many years to come. The design involved comparing the economic feasibility of GHP by comparing its cost to that of traditional HVAC systems via energy model, financial life cycle cost analysis of energy savings and capital cost, and finally by evaluating the compatibility of the mechanical design for GHP compared to traditional HVAC design. The project shows that GHP system design can be incorporated into the design of new commercial buildings if the design teams, architect, contractor, and owner coordinate carefully during the early phases of design. The public also benefits because the new CNCC campus is a center of education for the much of Northwestern Colorado, and students in K-12 programs (Science Spree 2010) through the CNCC two-year degree programs are already integrating geothermal and GHP technology. One of the greatest challenges met during this program was coordination of multiple engineering and development stakeholders. The leadership of Principle Investigator Pres. John Boyd of CNCC met this challenge by showing clear leadership in setting common goals and resolving conflicts early in the program.« less

  8. Geostationary platform systems concepts definition study. Volume 2: Technical, book 1

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The initial selection and definition of operational geostationary platform concepts is discussed. Candidate geostationary platform missions and payloads were identified from COMSAT, Aerospace, and NASA studies. These missions and payloads were cataloged; classified with to communications, military, or scientific uses; screened for application and compatibility with geostationary platforms; and analyzed to identify platform requirements. Two platform locations were then selected (Western Hemisphere - 110 deg W, and Atlantic - 15 deg W), and payloads allocated based on nominal and high traffic models. Trade studies were performed leading to recommendation of selected concepts. Of 30 Orbit Transfer Vehicle (0TV) configuration and operating mode options identified, 18 viable candidates compatible with the operational geostationary platform missions were selected for analysis. Each was considered using four platform operational modes - 8 or 16 year life, and serviced or nonserviced, providing a total of 72 OTV/platform-mode options. For final trade study concept selection, a cost program was developed considering payload and platform costs and weight; transportation unit and total costs for the shuttle and OTV; and operational costs such as assembly or construction time, mating time, and loiter time. Servicing costs were added for final analysis and recommended selection.

  9. Healthcare costs among adults with type 2 diabetes initiating saxagliptin or linagliptin: a US-based claims analysis.

    PubMed

    Kong, Amanda M; Farahbakhshian, Sepehr; Pendergraft, Trudy; Brouillette, Matthew A; Mukherjee, Biswarup; Smith, David M; Sheehan, John J

    2017-10-01

    To compare healthcare costs of adults with type 2 diabetes (T2D) after initiation of saxagliptin or linagliptin, two antidiabetic medications in the dipeptidyl peptidase-4 inhibitor medication class. Patients with T2D who were at least 18 years old and initiated saxagliptin or linagliptin (index date) between 1 June 2011 and 30 June 2014 were identified in the MarketScan Commercial and Medicare Supplemental Databases. All-cause healthcare costs and diabetes-related costs (T2D diagnosis on a medical claim and/or an antidiabetic medication claim) were measured in the 1 year follow-up period. Saxagliptin and linagliptin initiators were matched using propensity score methods. Cost ratios (CRs) and predicted costs were estimated from generalized linear models and recycled predictions. There were 34,560 saxagliptin initiators and 18,175 linagliptin initiators identified (mean ages 57 and 59; 55% and 56% male, respectively). Before matching, saxagliptin initiators had significantly lower all-cause total healthcare costs than linagliptin initiators (mean = $15,335 [SD $28,923] vs. mean = $20,069 [SD $48,541], p < .001) and significantly lower diabetes-related total healthcare costs (mean = $6109 [SD $13,851] vs. mean = $7393 [SD $26,041], p < .001). In matched analyses (n = 16,069 per cohort), saxagliptin initiators had lower all-cause follow-up costs than linagliptin initiators (CR = 0.953, 95% CI = 0.932-0.974, p < .001; predicted costs = $17,211 vs. $18,068). There was no significant difference in diabetes-related total costs after matching; however, diabetes-related medical costs were significantly lower for saxagliptin initiators (CR = 0.959, 95% CI = 0.927-0.993, p = 0.017; predicted costs = $3989 vs. $4159). Adult patients with T2D initiating treatment with saxagliptin had lower total all-cause healthcare costs and diabetes-related medical costs over 1 year compared with patients initiating treatment with linagliptin.

  10. Graph-associated entanglement cost of a multipartite state in exact and finite-block-length approximate constructions

    NASA Astrophysics Data System (ADS)

    Yamasaki, Hayata; Soeda, Akihito; Murao, Mio

    2017-09-01

    We introduce and analyze graph-associated entanglement cost, a generalization of the entanglement cost of quantum states to multipartite settings. We identify a necessary and sufficient condition for any multipartite entangled state to be constructible when quantum communication between the multiple parties is restricted to a quantum network represented by a tree. The condition for exact state construction is expressed in terms of the Schmidt ranks of the state defined with respect to edges of the tree. We also study approximate state construction and provide a second-order asymptotic analysis.

  11. The 1988 Inland Waterway Review

    DTIC Science & Technology

    1988-11-01

    Maintenance Costs ............. 91 Table 4.3 Major Rehabilitation Projects: ............................... 92 Table 4.4 Scheduled Constructed Projects in the...Maintenance Costs .......................... 100 Figure 4.7 Operations and Maintenance Costs Per Ton Mile in 1986 For Inland Waterways Suspect to Fuel Tax...application of study and construction cost -sharing. It also increased waterway fuel taxes and created the Inland Waterways Users Board. In effect, the Act

  12. Observed Parenting Behavior with Teens: Measurement Invariance and Predictive Validity Across Race

    PubMed Central

    Skinner, Martie L.; MacKenzie, Elizabeth P.; Haggerty, Kevin P.; Hill, Karl G.; Roberson, Kendra C.

    2011-01-01

    Previous reports supporting measurement equality between European American and African American families have often focused on self-reported risk factors or observed parent behavior with young children. This study examines equality of measurement of observer ratings of parenting behavior with adolescents during structured tasks; mean levels of observed parenting; and predictive validity of teen self-reports of antisocial behaviors and beliefs using a sample of 163 African American and 168 European American families. Multiple-group confirmatory factor analyses supported measurement invariance across ethnic groups for 4 measures of observed parenting behavior: prosocial rewards, psychological costs, antisocial rewards, and problem solving. Some mean-level differences were found: African American parents exhibited lower levels of prosocial rewards, higher levels of psychological costs, and lower problem solving when compared to European Americans. No significant mean difference was found in rewards for antisocial behavior. Multigroup structural equation models suggested comparable relationships across race (predictive validity) between parenting constructs and youth antisocial constructs (i.e., drug initiation, positive drug attitudes, antisocial attitudes, problem behaviors) in all but one of the tested relationships. This study adds to existing evidence that family-based interventions targeting parenting behaviors can be generalized to African American families. PMID:21787057

  13. Harnessing the power of enhanced data for healthcare quality improvement: lessons from a Minnesota Hospital Association Pilot Project.

    PubMed

    Pine, Michael; Sonneborn, Mark; Schindler, Joe; Stanek, Michael; Maeda, Jared Lane; Hanlon, Carrie

    2012-01-01

    The imperative to achieve quality improvement and cost-containment goals is driving healthcare organizations to make better use of existing health information. One strategy, the construction of hybrid data sets combining clinical and administrative data, has strong potential to improve the cost-effectiveness of hospital quality reporting processes, improve the accuracy of quality measures and rankings, and strengthen data systems. Through a two-year contract with the Agency for Healthcare Research and Quality, the Minnesota Hospital Association launched a pilot project in 2007 to link hospital clinical information to administrative data. Despite some initial challenges, this project was successful. Results showed that the use of hybrid data allowed for more accurate comparisons of risk-adjusted mortality and risk-adjusted complications across Minnesota hospitals. These increases in accuracy represent an important step toward targeting quality improvement efforts in Minnesota and provide important lessons that are being leveraged through ongoing projects to construct additional enhanced data sets. We explore the implementation challenges experienced during the Minnesota Pilot Project and their implications for hospitals pursuing similar data-enhancement projects. We also highlight the key lessons learned from the pilot project's success.

  14. Cost estimation using ministerial regulation of public work no. 11/2013 in construction projects

    NASA Astrophysics Data System (ADS)

    Arumsari, Putri; Juliastuti; Khalifah Al'farisi, Muhammad

    2017-12-01

    One of the first tasks in starting a construction project is to estimate the total cost of building a project. In Indonesia there are several standards that are used to calculate the cost estimation of a project. One of the standards used in based on the Ministerial Regulation of Public Work No. 11/2013. However in a construction project, contractor often has their own cost estimation based on their own calculation. This research aimed to compare the construction project total cost using calculation based on the Ministerial Regulation of Public Work No. 11/2013 against the contractor’s calculation. Two projects were used as case study to compare the results. The projects were a 4 storey building located in Pantai Indah Kapuk area (West Jakarta) and a warehouse located in Sentul (West Java) which was built by 2 different contractors. The cost estimation from both contractors’ calculation were compared to the one based on the Ministerial Regulation of Public Work No. 11/2013. It is found that there were differences between the two calculation around 1.80 % - 3.03% in total cost, in which the cost estimation based on Ministerial Regulation was higher than the contractors’ calculations.

  15. Contour Crafting Simulation Plan for Lunar Settlement Infrastructure Build-Up

    NASA Technical Reports Server (NTRS)

    Khoshnevis, B.; Carlson, A.; Leach N.; Thangavelu, M.

    2016-01-01

    Economically viable and reliable building systems and tool sets are being sought, examined and tested for extraterrestrial infrastructure buildup. This project focused on a unique architecture weaving the robotic building construction technology with designs for assisting rapid buildup of initial operational capability Lunar and Martian bases. The project aimed to study new methodologies to construct certain crucial infrastructure elements in order to evaluate the merits, limitations and feasibility of adapting and using such technologies for extraterrestrial application. Current extraterrestrial settlement buildup philosophy holds that in order to minimize the materials needed to be flown in, at great transportation costs, strategies that maximize the use of locally available resources must be adopted. Tools and equipment flown as cargo from Earth are proposed to build required infrastructure to support future missions and settlements on the Moon and Mars.

  16. Creating constructive outcomes in conflict.

    PubMed

    Orchard, B

    1998-06-01

    1. Conflict and disagreement are a fact of business life. Effort toward optomizing differences rather than minimizing them is a value added activity--leading to greater creativity, increasing levels of respect in relationships, and better solutions. 2. Proactively looking at potential conflict--where diasgreeing parties are often inherent and/or predictable--can save energy, relationships, and costly mistakes. Diagnosing or "reading" a situation and planning an approach is wise. 3. Several options or responses are available when facing conflict. Knowing when to use a given response is an important interpersonal skill. Relying on learned, habitual, and exclusive approaches to conflict may be limiting. 4. Implementation of effective conflict resolution is a function of attitude, initiative, and flexibility. An exploratory posture and a willingness to learn are constructive in attempting to reach agreements with optimum short and long term effect.

  17. Y-12 Industrial Landfill V. Permit application modifications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-09-01

    This report contains the modifications in operations and design to meet the Tennessee Department of Environment and Conversation (TDEC) July 10, 1993, amendments to the regulations for Class 2 landfills. These modifications, though extensive in design and construction cost, are considered minor revisions and should not require a processing fee. Area 1 of ILF V, comprising approximately 20% of the ILF V footprint, was designed and submitted to TDEC prior to the implementation of current regulations. This initial area was constructed with a compacted clay liner and leachate collection system, and became operational in April 1994. The current regulations requiremore » landfills to have a composite liner with leachate collection system and closure cap. Modifications to upgrade Areas 2 and 3 of ILF V to meet the current TDEC requirements are included.« less

  18. Procurement Forms | NREL

    Science.gov Websites

    Certificate of Current Cost or Pricing Data Construction Specific Forms Pre-Award Documents Construction and manuals) Cost and Pricing Data Definitions Design-Build / Price Proposal Form Information

  19. Developing and integrating a practice model for health finance reform into wound healing programs: an examination of the triple aim approach.

    PubMed

    Flattau, Anna; Thompson, Maureen; Meara, Anne

    2013-10-01

    Throughout the United States, government and private payers are exploring new payment models such as accountable care organizations and shared savings agreements. These models are widely based on the construct of the Triple Aim, a set of three principles for health services reform: improving population-based outcomes, improving patient care experiences, and reducing costs through better delivery systems. Wound programs may adapt to the new health financing environment by incorporating initiatives known to promote the Triple Aim, such as diabetes amputation reduction and pressure ulcer prevention programs, and by rethinking how health services can best be delivered to meet these new criteria. The existing literature supports that programmatic approaches can improve care, quality, and cost, especially in the field of diabetic foot ulcers. Wound healing programs have opportunities to develop new business plan models that provide quality, cost-efficient care to their patient population and to be leaders in the development of new types of partnerships with payers and health delivery organizations.

  20. Evaluation of selected chemical processes for production of low-cost silicon

    NASA Technical Reports Server (NTRS)

    Blocher, J. M., Jr.; Browning, M. F.; Wilson, W. J.; Carmichael, D. C.

    1976-01-01

    Plant construction costs and manufacturing costs were estimated for the production of solar-grade silicon by the reduction of silicon tetrachloride in a fluidized bed of seed particles, and several modifications of the iodide process using either thermal decomposition on heated filaments (rods) or hydrogen reduction in a fluidized bed of seed particles. Energy consumption data for the zinc reduction process and each of the iodide process options are given and all appear to be acceptable from the standpoint of energy pay back. Information is presented on the experimental zinc reduction of SiCl4 and electrolytic recovery of zinc from ZnCl2. All of the experimental work performed thus far has supported the initial assumption as to technical feasibility of producing semiconductor silicon by the zinc reduction or iodide processes proposed. The results of a more thorough thermodynamic evaluation of the iodination of silicon oxide/carbon mixtures are presented which explain apparent inconsistencies in an earlier cursory examination of the system.

  1. Benchmark tests for a Formula SAE Student car prototyping

    NASA Astrophysics Data System (ADS)

    Mariasiu, Florin

    2011-12-01

    Aerodynamic characteristics of a vehicle are important elements in its design and construction. A low drag coefficient brings significant fuel savings and increased engine power efficiency. In designing and developing vehicles trough computer simulation process to determine the vehicles aerodynamic characteristics are using dedicated CFD (Computer Fluid Dynamics) software packages. However, the results obtained by this faster and cheaper method, are validated by experiments in wind tunnels tests, which are expensive and were complex testing equipment are used in relatively high costs. Therefore, the emergence and development of new low-cost testing methods to validate CFD simulation results would bring great economic benefits for auto vehicles prototyping process. This paper presents the initial development process of a Formula SAE Student race-car prototype using CFD simulation and also present a measurement system based on low-cost sensors through which CFD simulation results were experimentally validated. CFD software package used for simulation was Solid Works with the FloXpress add-on and experimental measurement system was built using four piezoresistive force sensors FlexiForce type.

  2. Eighth-order explicit two-step hybrid methods with symmetric nodes and weights for solving orbital and oscillatory IVPs

    NASA Astrophysics Data System (ADS)

    Franco, J. M.; Rández, L.

    The construction of new two-step hybrid (TSH) methods of explicit type with symmetric nodes and weights for the numerical integration of orbital and oscillatory second-order initial value problems (IVPs) is analyzed. These methods attain algebraic order eight with a computational cost of six or eight function evaluations per step (it is one of the lowest costs that we know in the literature) and they are optimal among the TSH methods in the sense that they reach a certain order of accuracy with minimal cost per step. The new TSH schemes also have high dispersion and dissipation orders (greater than 8) in order to be adapted to the solution of IVPs with oscillatory solutions. The numerical experiments carried out with several orbital and oscillatory problems show that the new eighth-order explicit TSH methods are more efficient than other standard TSH or Numerov-type methods proposed in the scientific literature.

  3. Moly99 Production Facility: Report on Beamline Components, Requirements, Costs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bishofberger, Kip A.

    2015-12-23

    In FY14 we completed the design of the beam line for the linear accelerator production design concept. This design included a set of three bending magnets, quadrupole focusing magnets, and octopoles to flatten the beam on target. This design was generic and applicable to multiple different accelerators if necessary. In FY15 we built on that work to create specifications for the individual beam optic elements, including power supply requirements. This report captures the specification of beam line components with initial cost estimates for the NorthStar production facility.This report is organized as follows: The motivation of the beamline design is introducedmore » briefly, along with renderings of the design. After that, a specific list is provided, which accounts for each beamline component, including part numbers and costs, to construct the beamline. After that, this report details the important sections of the beamline and individual components. A final summary and list of follow-on activities completes this report.« less

  4. Management of Knowledge Representation Standards Activities

    NASA Technical Reports Server (NTRS)

    Patil, Ramesh S.

    1993-01-01

    Ever since the mid-seventies, researchers have recognized that capturing knowledge is the key to building large and powerful AI systems. In the years since, we have also found that representing knowledge is difficult and time consuming. In spite of the tools developed to help with knowledge acquisition, knowledge base construction remains one of the major costs in building an Al system: For almost every system we build, a new knowledge base must be constructed from scratch. As a result, most systems remain small to medium in size. Even if we build several systems within a general area, such as medicine or electronics diagnosis, significant portions of the domain must be represented for every system we create. The cost of this duplication of effort has been high and will become prohibitive as we attempt to build larger and larger systems. To overcome this barrier we must find ways of preserving existing knowledge bases and of sharing, re-using, and building on them. This report describes the efforts undertaken over the last two years to identify the issues underlying the current difficulties in sharing and reuse, and a community wide initiative to overcome them. First, we discuss four bottlenecks to sharing and reuse, present a vision of a future in which these bottlenecks have been ameliorated, and describe the efforts of the initiative's four working groups to address these bottlenecks. We then address the supporting technology and infrastructure that is critical to enabling the vision of the future. Finally, we consider topics of longer-range interest by reviewing some of the research issues raised by our vision.

  5. Small-scale, hydrogen-oxidizing-denitrifying bioreactor for treatment of nitrate-contaminated drinking water.

    PubMed

    Smith, Richard L; Buckwalter, Seanne P; Repert, Deborah A; Miller, Daniel N

    2005-05-01

    Nitrate removal by hydrogen-coupled denitrification was examined using flow-through, packed-bed bioreactors to develop a small-scale, cost effective system for treating nitrate-contaminated drinking-water supplies. Nitrate removal was accomplished using a Rhodocyclus sp., strain HOD 5, isolated from a sole-source drinking-water aquifer. The autotrophic capacity of the purple non-sulfur photosynthetic bacterium made it particularly adept for this purpose. Initial tests used a commercial bioreactor filled with glass beads and countercurrent, non-sterile flow of an autotrophic, air-saturated, growth medium and hydrogen gas. Complete removal of 2 mM nitrate was achieved for more than 300 days of operation at a 2-h retention time. A low-cost hydrogen generator/bioreactor system was then constructed from readily available materials as a water treatment approach using the Rhodocyclus strain. After initial tests with the growth medium, the constructed system was tested using nitrate-amended drinking water obtained from fractured granite and sandstone aquifers, with moderate and low TDS loads, respectively. Incomplete nitrate removal was evident in both water types, with high-nitrite concentrations in the bioreactor output, due to a pH increase, which inhibited nitrite reduction. This was rectified by including carbon dioxide in the hydrogen stream. Additionally, complete nitrate removal was accomplished with wastewater-impacted surface water, with a concurrent decrease in dissolved organic carbon. The results of this study using three chemically distinct water supplies demonstrate that hydrogen-coupled denitrification can serve as the basis for small-scale remediation and that pilot-scale testing might be the next logical step.

  6. Small-scale, hydrogen-oxidizing-denitrifying bioreactor for treatment of nitrate-contaminated drinking water

    USGS Publications Warehouse

    Smith, R.L.; Buckwalter, S.P.; Repert, D.A.; Miller, D.N.

    2005-01-01

    Nitrate removal by hydrogen-coupled denitrification was examined using flow-through, packed-bed bioreactors to develop a small-scale, cost effective system for treating nitrate-contaminated drinking-water supplies. Nitrate removal was accomplished using a Rhodocyclus sp., strain HOD 5, isolated from a sole-source drinking-water aquifer. The autotrophic capacity of the purple non-sulfur photosynthetic bacterium made it particularly adept for this purpose. Initial tests used a commercial bioreactor filled with glass beads and countercurrent, non-sterile flow of an autotrophic, air-saturated, growth medium and hydrogen gas. Complete removal of 2 mM nitrate was achieved for more than 300 days of operation at a 2-h retention time. A low-cost hydrogen generator/bioreactor system was then constructed from readily available materials as a water treatment approach using the Rhodocyclus strain. After initial tests with the growth medium, the constructed system was tested using nitrate-amended drinking water obtained from fractured granite and sandstone aquifers, with moderate and low TDS loads, respectively. Incomplete nitrate removal was evident in both water types, with high-nitrite concentrations in the bioreactor output, due to a pH increase, which inhibited nitrite reduction. This was rectified by including carbon dioxide in the hydrogen stream. Additionally, complete nitrate removal was accomplished with wastewater-impacted surface water, with a concurrent decrease in dissolved organic carbon. The results of this study using three chemically distinct water supplies demonstrate that hydrogen-coupled denitrification can serve as the basis for small-scale remediation and that pilot-scale testing might be the next logical step.

  7. Use Hardwoods for Building Components

    Treesearch

    Glenn A. Cooper; William W. Rice

    1968-01-01

    Describes a system for prefabricating structural units from hardwoods for use in floors, roofs, and walls of a-frame or post-and-beam type construction. The interior face of the unit is decorative paneling; the exterior face is sheathing. Use of the system could reduce prefabricated house construction costs compared to conventional construction costs.

  8. Preservation treatment for wood bridge application

    Treesearch

    Jake Bigelow; Stan Lebow; Carol A. Clausen; Lowell Greimann; Terry J. Wipf

    2009-01-01

    Timber can often be a cost-effective construction material for new bridges. The durability of the bridge greatly depends on proper attention to construction details and fabrication, as well as proper preservative treatment before, during, and after construction. Material repair and replacement costs for bridges are a considerable expense for highway agencies. To...

  9. Cost viability of 3D printed house in UK

    NASA Astrophysics Data System (ADS)

    Tobi, A. L. Mohd; Omar, S. A.; Yehia, Z.; Al-Ojaili, S.; Hashim, A.; Orhan, O.

    2018-03-01

    UK has been facing housing crisis due to the rising price of the property on sale. This paper will look into the viability of 3D printing technology as an alternative way for house construction on UK. The analysis will be carried out based on the data until the year of 2014 due to limited resources availability. Details cost breakdown on average size house construction cost in UK were analysed and relate to the cost viability of 3D printing technology in reducing the house price in UK. It is found that the 3D printing generates saving of up to around 35% out of total house price in UK. This cost saving comes from the 3D printed construction of walls and foundations for material and labour cost.

  10. The Physician Values in Practice Scale: Construction and Initial Validation

    ERIC Educational Resources Information Center

    Hartung, Paul J.; Taber, Brian J.; Richard, George V.

    2005-01-01

    Measures of values typically appraise the construct globally, across life domains or relative to a broad life domain such as work. We conducted two studies to construct and initially validate an occupation- and context-specific values measure. Study 1, based on a sample of 192 medical students, describes the initial construction and item analysis…

  11. Estimated Costs for Delivery of HIV Antiretroviral Therapy to Individuals with CD4+ T-Cell Counts >350 cells/uL in Rural Uganda.

    PubMed

    Jain, Vivek; Chang, Wei; Byonanebye, Dathan M; Owaraganise, Asiphas; Twinomuhwezi, Ellon; Amanyire, Gideon; Black, Douglas; Marseille, Elliot; Kamya, Moses R; Havlir, Diane V; Kahn, James G

    2015-01-01

    Evidence favoring earlier HIV ART initiation at high CD4+ T-cell counts (CD4>350/uL) has grown, and guidelines now recommend earlier HIV treatment. However, the cost of providing ART to individuals with CD4>350 in Sub-Saharan Africa has not been well estimated. This remains a major barrier to optimal global cost projections for accelerating the scale-up of ART. Our objective was to compute costs of ART delivery to high CD4+count individuals in a typical rural Ugandan health center-based HIV clinic, and use these data to construct scenarios of efficient ART scale-up. Within a clinical study evaluating streamlined ART delivery to 197 individuals with CD4+ cell counts >350 cells/uL (EARLI Study: NCT01479634) in Mbarara, Uganda, we performed a micro-costing analysis of administrative records, ART prices, and time-and-motion analysis of staff work patterns. We computed observed per-person-per-year (ppy) costs, and constructed models estimating costs under several increasingly efficient ART scale-up scenarios using local salaries, lowest drug prices, optimized patient loads, and inclusion of viral load (VL) testing. Among 197 individuals enrolled in the EARLI Study, median pre-ART CD4+ cell count was 569/uL (IQR 451-716). Observed ART delivery cost was $628 ppy at steady state. Models using local salaries and only core laboratory tests estimated costs of $529/$445 ppy (+/-VL testing, respectively). Models with lower salaries, lowest ART prices, and optimized healthcare worker schedules reduced costs by $100-200 ppy. Costs in a maximally efficient scale-up model were $320/$236 ppy (+/- VL testing). This included $39 for personnel, $106 for ART, $130/$46 for laboratory tests, and $46 for administrative/other costs. A key limitation of this study is its derivation and extrapolation of costs from one large rural treatment program of high CD4+ count individuals. In a Ugandan HIV clinic, ART delivery costs--including VL testing--for individuals with CD4>350 were similar to estimates from high-efficiency programs. In higher efficiency scale-up models, costs were substantially lower. These favorable costs may be achieved because high CD4+ count patients are often asymptomatic, facilitating more efficient streamlined ART delivery. Our work provides a framework for calculating costs of efficient ART scale-up models using accessible data from specific programs and regions.

  12. The Program Administrator Cost of Saved Energy for Utility Customer-Funded Energy Efficiency Programs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Billingsley, Megan A.; Hoffman, Ian M.; Stuart, Elizabeth

    End-use energy efficiency is increasingly being relied upon as a resource for meeting electricity and natural gas utility system needs within the United States. There is a direct connection between the maturation of energy efficiency as a resource and the need for consistent, high-quality data and reporting of efficiency program costs and impacts. To support this effort, LBNL initiated the Cost of Saved Energy Project (CSE Project) and created a Demand-Side Management (DSM) Program Impacts Database to provide a resource for policy makers, regulators, and the efficiency industry as a whole. This study is the first technical report of themore » LBNL CSE Project and provides an overview of the project scope, approach, and initial findings, including: • Providing a proof of concept that the program-level cost and savings data can be collected, organized, and analyzed in a systematic fashion; • Presenting initial program, sector, and portfolio level results for the program administrator CSE for a recent time period (2009-2011); and • Encouraging state and regional entities to establish common reporting definitions and formats that would make the collection and comparison of CSE data more reliable. The LBNL DSM Program Impacts Database includes the program results reported to state regulators by more than 100 program administrators in 31 states, primarily for the years 2009–2011. In total, we have compiled cost and energy savings data on more than 1,700 programs over one or more program-years for a total of more than 4,000 program-years’ worth of data, providing a rich dataset for analyses. We use the information to report costs-per-unit of electricity and natural gas savings for utility customer-funded, end-use energy efficiency programs. The program administrator CSE values are presented at national, state, and regional levels by market sector (e.g., commercial, industrial, residential) and by program type (e.g., residential whole home programs, commercial new construction, commercial/industrial custom rebate programs). In this report, the focus is on gross energy savings and the costs borne by the program administrator—including administration, payments to implementation contractors, marketing, incentives to program participants (end users) and both midstream and upstream trade allies, and evaluation costs. We collected data on net savings and costs incurred by program participants. However, there were insufficient data on participant cost contributions, and uncertainty and variability in the ways in which net savings were reported and defined across states (and program administrators).« less

  13. 48 CFR 1845.7101-3 - Unit acquisition cost.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... buildings and other facilities. (7) An appropriate share of the cost of the equipment and facilities used in construction work. (8) Fixed equipment and related installation costs required for activities in a building or... construction work. (10) Legal and recording fees and damage claims. (11) Fair values of facilities and...

  14. 48 CFR 1845.7101-3 - Unit acquisition cost.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... buildings and other facilities. (7) An appropriate share of the cost of the equipment and facilities used in construction work. (8) Fixed equipment and related installation costs required for activities in a building or... construction work. (10) Legal and recording fees and damage claims. (11) Fair values of facilities and...

  15. 48 CFR 1845.7101-3 - Unit acquisition cost.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... buildings and other facilities. (7) An appropriate share of the cost of the equipment and facilities used in construction work. (8) Fixed equipment and related installation costs required for activities in a building or... construction work. (10) Legal and recording fees and damage claims. (11) Fair values of facilities and...

  16. 48 CFR 1845.7101-3 - Unit acquisition cost.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... buildings and other facilities. (7) An appropriate share of the cost of the equipment and facilities used in construction work. (8) Fixed equipment and related installation costs required for activities in a building or... construction work. (10) Legal and recording fees and damage claims. (11) Fair values of facilities and...

  17. Illumina Unamplified Indexed Library Construction: An Automated Approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hack, Christopher A.; Sczyrba, Alexander; Cheng, Jan-Fang

    Manual library construction is a limiting factor in Illumina sequencing. Constructing libraries by hand is costly, time-consuming, low-throughput, and ergonomically hazardous, and constructing multiple libraries introduces risk of library failure due to pipetting errors. The ability to construct multiple libraries simultaneously in automated fashion represents significant cost and time savings. Here we present a strategy to construct up to 96 unamplified indexed libraries using Illumina TruSeq reagents and a Biomek FX robotic platform. We also present data to indicate that this library construction method has little or no risk of cross-contamination between samples.

  18. Reverse shoulder arthroplasty glenoid fixation: is there a benefit in using four instead of two screws?

    PubMed

    James, Jaison; Allison, Mari A; Werner, Frederick W; McBride, Devin E; Basu, Niladri N; Sutton, Levi G; Nanavati, Vipul N

    2013-08-01

    To allow osseous integration to occur and thus provide long-term stability, initial glenoid baseplate fixation must be sufficiently rigid. A major contributing factor to initial rigid fixation is baseplate screw fixation. Current baseplate designs use a 4-screw fixation construct. However, recent literature suggests adequate fixation can be achieved with fewer than 4 screws. The purpose of the present study was to determine whether a 4-screw construct provides more baseplate stability than a 2-screw construct. A flat-backed glenoid baseplate with 4 screw hole options was implanted into 6 matched pairs of cadaver scapulas using standard surgical technique. Within each pair, 2 screws or 4 screws were implanted in a randomized fashion. A glenosphere was attached allowing cyclic loading in an inferior-to-superior direction and in an anterior-to-posterior direction. Baseplate motion was measured using 4 linear voltage displacement transducers evenly spaced around the glenosphere. There was no statistical difference in the average peak central displacements between fixation with 2 or 4 screws (P = .338). Statistical increases in average peak central displacement with increasing load (P < .001) and with repetitive loading (P < .002) were found. This study demonstrates no statistical difference in baseplate motion between 2-screw and 4-screw constructs. Therefore, using fewer screws could potentially lead to a reduction in operative time, cost, and risk, with no significant negative effect on overall implant baseplate motion. Copyright © 2013 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

  19. Multiple Benefits.

    ERIC Educational Resources Information Center

    Kreider, Beth

    1997-01-01

    Discusses the benefits of dome architecture for a community's middle- and high-school multi-purpose facility. The dome construction is revealed as being cost effective in construction and in maintenance and energy costs. (GR)

  20. Shell Structure Water Cellar’s Rapid Construct Technology

    NASA Astrophysics Data System (ADS)

    Xian Zhuang, Wen; Qing Yin, De; Chen, Shu Fa

    2018-05-01

    Tradition concrete water cellar’s problems, such as high cost, long construction term, easy to crack, are pointed out. A new construct method, and it’s matching airbag mould, of constructing concrete shell structure water cellars, are introduced. Combine with full-scale verifying cellar’s construct test, full-load water storage test, analyzed the technology in terms of construction term, cost, crack resistance, air bag pressure etc. It is believed that this new technology can successfully solve the problems that tradition technology has, and it will have a good prospect in rainfall resources utilization.

  1. Characteristics of worker accidents on NYSDOT construction projects.

    PubMed

    Mohan, Satish; Zech, Wesley C

    2005-01-01

    This paper aims at providing cost-effective safety measures to protect construction workers in highway work zones, based on real data. Two types of accidents that occur in work zones were: (a) construction work area accidents, and (b) traffic accidents involving construction worker(s). A detailed analysis of work zone accidents involving 36 fatalities and 3,055 severe injuries to construction workers on New York State Department of Transportation (NYSDOT) construction projects from 1990 to 2001 established that five accident types: (a) Struck/Pinned by Large Equipment, (b) Trip or Fall (elevated), (c) Contact w/Electrical or Gas Utility, (d) Struck-by Moving/Falling Load, and (e) Crane/Lift Device Failure accounted for nearly 96% of the fatal accidents, nearly 63% of the hospital-level injury accidents, and nearly 91% of the total costs. These construction work area accidents had a total cost of $133.8 million. Traffic accidents that involve contractors' employees were also examined. Statistical analyses of the traffic accidents established that five traffic accident types: (a) Work Space Intrusion, (b) Worker Struck-by Vehicle Inside Work Space, (c) Flagger Struck-by Vehicle, (d) Worker Struck-by Vehicle Entering/Exiting Work Space, and (e) Construction Equipment Struck-by Vehicle Inside Work Space accounted for nearly 86% of the fatal, nearly 70% of the hospital-level injury and minor injury traffic accidents, and $45.4 million (79.4%) of the total traffic accident costs. The results of this paper provide real statistics on construction worker related accidents reported on construction work zones. Potential preventions based on real statistics have also been suggested. The ranking of accident types, both within the work area as well as in traffic, will guide the heavy highway contractor and owner agencies in identifying the most cost effective safety preventions.

  2. 41 CFR 301-70.506 - How do we define actual cost and constructive cost when an employee interrupts a travel...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... appropriate en route travel time. [FTR Amdt. 70, 63 FR 15971, Apr. 1, 1998. Redesignated by FTR Amdt. 108, 67... cost and constructive cost when an employee interrupts a travel assignment because of an incapacitating illness or injury? 301-70.506 Section 301-70.506 Public Contracts and Property Management Federal Travel...

  3. 41 CFR 301-70.506 - How do we define actual cost and constructive cost when an employee interrupts a travel...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... appropriate en route travel time. [FTR Amdt. 70, 63 FR 15971, Apr. 1, 1998. Redesignated by FTR Amdt. 108, 67... cost and constructive cost when an employee interrupts a travel assignment because of an incapacitating illness or injury? 301-70.506 Section 301-70.506 Public Contracts and Property Management Federal Travel...

  4. 41 CFR 301-70.506 - How do we define actual cost and constructive cost when an employee interrupts a travel...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... appropriate en route travel time. [FTR Amdt. 70, 63 FR 15971, Apr. 1, 1998. Redesignated by FTR Amdt. 108, 67... cost and constructive cost when an employee interrupts a travel assignment because of an incapacitating illness or injury? 301-70.506 Section 301-70.506 Public Contracts and Property Management Federal Travel...

  5. 41 CFR 301-70.506 - How do we define actual cost and constructive cost when an employee interrupts a travel...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... appropriate en route travel time. [FTR Amdt. 70, 63 FR 15971, Apr. 1, 1998. Redesignated by FTR Amdt. 108, 67... cost and constructive cost when an employee interrupts a travel assignment because of an incapacitating illness or injury? 301-70.506 Section 301-70.506 Public Contracts and Property Management Federal Travel...

  6. 41 CFR 301-70.506 - How do we define actual cost and constructive cost when an employee interrupts a travel...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... appropriate en route travel time. [FTR Amdt. 70, 63 FR 15971, Apr. 1, 1998. Redesignated by FTR Amdt. 108, 67... cost and constructive cost when an employee interrupts a travel assignment because of an incapacitating illness or injury? 301-70.506 Section 301-70.506 Public Contracts and Property Management Federal Travel...

  7. Photovoltaic system criteria documents. Volume 1: Guidelines for evaluating the management and operations planning of photovoltaic applications

    NASA Technical Reports Server (NTRS)

    Koenig, John C.; Billitti, Joseph W.; Tallon, John M.

    1979-01-01

    Guidelines are provided to the Field Centers for organization, scheduling, project and cost control, and performance in the areas of project management and operations planning for Photovoltaics Test and Applications. These guidelines may be used in organizing a T and A Project Team for system design/test, site construction and operation, and as the basis for evaluating T and A proposals. The attributes are described for project management and operations planning to be used by the Field Centers. Specifically, all project management and operational issues affecting costs, schedules and performance of photovoltaic systems are addressed. Photovoltaic tests and applications include residential, intermediate load center, central station, and stand-alone systems. The sub-categories of system maturity considered are: Initial System Evaluation Experiments (ISEE); System Readiness Experiments (SRE); and Commercial Readiness Demonstration Projects (CRDP).

  8. The 3D Elevation Program: summary for Missouri

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  9. The 3D Elevation Program: summary for Montana

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  10. The 3D Elevation Program: summary for Louisiana

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  11. The 3D Elevation Program: summary for Tennessee

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  12. The 3D Elevation Program: summary for New York

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  13. 3D Elevation Program: summary for Vermont

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  14. The 3D Elevation Program: summary for Maryland

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  15. The 3D Elevation Program: summary for Ohio

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation's natural and constructed features.

  16. The 3D Elevation Program: summary for Indiana

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation's natural and constructed features.

  17. The 3D Elevation Program: summary for Maine

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  18. The 3D Elevation Program: summary for Kentucky

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  19. The 3D Elevation Program: summary for Oregon

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  20. The 3D Elevation Program: summary for North Dakota

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  1. The 3D Elevation Program: summary for Florida

    USGS Publications Warehouse

    Carswell, William J.

    2013-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the OMB Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  2. 3D Elevation Program: summary for Nebraska

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  3. The 3D Elevation Program: summary for Alabama

    USGS Publications Warehouse

    Carswell, William J.

    2013-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A-16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  4. 42 CFR 417.930 - Initial costs of operation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Initial costs of operation. 417.930 Section 417.930... PREPAYMENT PLANS Administration of Outstanding Loans and Loan Guarantees § 417.930 Initial costs of operation. Under section 1305 of the PHS, loans and loan guarantees were awarded for initial costs of operation of...

  5. Defense Base Realignment and Closure Budget Data for Naval Air Technical Training Center, Naval Air Station Pensacola, Florida

    DTIC Science & Technology

    1994-06-07

    023- S -94 Military Construction Projects Budgeted January 14, 1994 and Programmed for Bases Identified for Closure or Realignment 028-C-93...deferred to this analysis as the more accurate basis for design and construction costs, rather than the gross estimates in the 1391’ s submitted much...solutions( s ), it is imperative that design and construction costs, operation/maintenance costs, the specific health care needs of the population to

  6. Construction of a low-cost detector to identify dissolved metals in aqueous media by fluorescence spectroscopy: design and perspectives.

    NASA Astrophysics Data System (ADS)

    González, M.; Montaño, M.; Hoyo, C.

    2017-01-01

    We have constructed a low cost fluorescence detector model to determine the presence of some heavy metals in an aqueous medium. In particular, we focus on metals which cause public health problems in our country. We did the first tests with standard samples of Hg (II). The innovative features of this instrument are its small dimensions (9 dm3) and the low cost of materials used in its construction.

  7. Estimated Costs for Delivery of HIV Antiretroviral Therapy to Individuals with CD4+ T-Cell Counts >350 cells/uL in Rural Uganda

    PubMed Central

    Jain, Vivek; Chang, Wei; Byonanebye, Dathan M.; Owaraganise, Asiphas; Twinomuhwezi, Ellon; Amanyire, Gideon; Black, Douglas; Marseille, Elliot; Kamya, Moses R.; Havlir, Diane V.; Kahn, James G.

    2015-01-01

    Background Evidence favoring earlier HIV ART initiation at high CD4+ T-cell counts (CD4>350/uL) has grown, and guidelines now recommend earlier HIV treatment. However, the cost of providing ART to individuals with CD4>350 in Sub-Saharan Africa has not been well estimated. This remains a major barrier to optimal global cost projections for accelerating the scale-up of ART. Our objective was to compute costs of ART delivery to high CD4+count individuals in a typical rural Ugandan health center-based HIV clinic, and use these data to construct scenarios of efficient ART scale-up. Methods Within a clinical study evaluating streamlined ART delivery to 197 individuals with CD4+ cell counts >350 cells/uL (EARLI Study: NCT01479634) in Mbarara, Uganda, we performed a micro-costing analysis of administrative records, ART prices, and time-and-motion analysis of staff work patterns. We computed observed per-person-per-year (ppy) costs, and constructed models estimating costs under several increasingly efficient ART scale-up scenarios using local salaries, lowest drug prices, optimized patient loads, and inclusion of viral load (VL) testing. Findings Among 197 individuals enrolled in the EARLI Study, median pre-ART CD4+ cell count was 569/uL (IQR 451–716). Observed ART delivery cost was $628 ppy at steady state. Models using local salaries and only core laboratory tests estimated costs of $529/$445 ppy (+/-VL testing, respectively). Models with lower salaries, lowest ART prices, and optimized healthcare worker schedules reduced costs by $100–200 ppy. Costs in a maximally efficient scale-up model were $320/$236 ppy (+/- VL testing). This included $39 for personnel, $106 for ART, $130/$46 for laboratory tests, and $46 for administrative/other costs. A key limitation of this study is its derivation and extrapolation of costs from one large rural treatment program of high CD4+ count individuals. Conclusions In a Ugandan HIV clinic, ART delivery costs—including VL testing—for individuals with CD4>350 were similar to estimates from high-efficiency programs. In higher efficiency scale-up models, costs were substantially lower. These favorable costs may be achieved because high CD4+ count patients are often asymptomatic, facilitating more efficient streamlined ART delivery. Our work provides a framework for calculating costs of efficient ART scale-up models using accessible data from specific programs and regions. PMID:26632823

  8. An Analysis of Cost Premiums and Losses Associated with USAF Military Construction (MILCON)

    DTIC Science & Technology

    2013-03-01

    Corps of Engineers (USACE) or the Naval Facilities Engineering Command (NAVFAC) for design and construction of the annual military construction...AFCEC in lieu of AFCEE or AFCESA. The selection, and policies, of design and construction agents may cause cost premiums for Air Force MILCON...private industry best practices such as relational contracting, schedule performance, and design -build procurement methods. All of these research

  9. Construction of a low-cost luximeter

    NASA Astrophysics Data System (ADS)

    Pedroso, L. S.; de Macedo, J. A.; de Araújo, M. S. T.; Voelzke, M. R.

    2016-04-01

    This paper proposes the construction of an electronic instrument called digital luximeter, combining simplicity and low cost, making it simpler and cheaper than those on the market. Its construction tends to facilitate dissemination and access to this type of measuring instrument between high school teachers and educational institutions, making it ideal to be a science lab.

  10. 13 CFR 308.1 - Use of funds in Projects constructed under projected cost.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Use of funds in Projects constructed under projected cost. 308.1 Section 308.1 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PERFORMANCE INCENTIVES § 308.1 Use of funds in Projects constructed under...

  11. Preventing and Treating Peri-Implantitis: A Cost-Effectiveness Analysis.

    PubMed

    Schwendicke, Falk; Tu, Yu-Kang; Stolpe, Michael

    2015-09-01

    A large number of treatments for peri-implantitis are available, but their cost-effectiveness remains uncertain. This study evaluates the cost-effectiveness of preventing and treating peri-implantitis. A Markov model was constructed that followed each implant over 20 years. Supportive implant therapy (SIT) for managing peri-implant mucositis and preventing development of peri-implantitis was either provided or not. Risk of peri-implantitis was assumed to be affected by SIT and the patient's risk profile. If peri-implantitis occurred, 11 treatment strategies (non-surgical or surgical debridement alone or combined with adjunct therapies) were compared. Treatments and risk profiles determined disease progression. Modeling was performed based on systematically collected data. Primary outcomes were costs and proportion of lost implants, as assessed via Monte Carlo microsimulations. Not providing SIT and performing only non-surgical debridement was both least costly and least effective. The next best (more costly and effective) option was to provide SIT and perform surgical debridement (additional 0.89 euros per 1% fewer implants lost). The most effective option included bone grafts, membranes, and laser treatment (56 euros per 1%). For patients at high risk, the cost-effectiveness of SIT increased, whereas in low-risk groups, a cost-optimized strategy was cost-effective. Although clinical decision-making will be guided mainly by clinical condition, cost-effectiveness analyses might add another perspective. Based on these findings, an unambiguous comparative effectiveness ranking was not established. However, cost-effectiveness was predominantly determined by provision of SIT and initial treatment costs. Transferability of these findings to other healthcare systems needs further confirmation.

  12. Low-Cost alpha Alane for Hydrogen Storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fabian, Tibor; Petrie, Mark; Crouch-Baker, Steven

    This project was directed towards the further development of the Savannah River National Laboratory (SRNL) lab-scale electrochemical synthesis of the hydrogen storage material alpha-alane and Ardica Technologies-SRI International (SRI) chemical downstream processes that are necessary to meet DoE cost metrics and transition alpha-alane synthesis to an industrial scale. Ardica has demonstrated the use of alpha-alane in a fuel-cell system for the U.S. Army WFC20 20W soldier power system that has successfully passed initial field trials with individual soldiers. While alpha-alane has been clearly identified as a desirable hydrogen storage material, cost-effective means for its production and regeneration on a scalemore » of use applicable to the industry have yet to be established. We focused on three, principal development areas: 1. The construction of a comprehensive engineering techno-economic model to establish the production costs of alpha-alane by both electrochemical and chemical routes at scale. 2. The identification of critical, cost-saving design elements of the electrochemical cell and the quantification of the product yields of the primary electrochemical process. A moving particle-bed reactor design was constructed and operated. 3. The experimental quantification of the product yields of candidate downstream chemical processes necessary to produce alpha-alane to complete the most cost-effective overall manufacturing process. Our techno-economic model shows that under key assumptions most 2015 and 2020 DOE hydrogen storage system cost targets for low and medium power can be achieved using the electrochemical alane synthesis process. To meet the most aggressive 2020 storage system cost target, $1/g, our model indicates that 420 metric tons per year (MT/y) production of alpha-alane is required. Laboratory-scale experimental work demonstrated that the yields of two of the three critical component steps within the overall “electrochemical process” were sufficiently high to meet this production target. In the case of the yield of the third step, the crystallization of alpha-alane from the primary alane-related product of the electrochemical reaction, further development is required.« less

  13. 36 CFR 51.56 - How will the construction cost for purposes of leasehold surrender interest value be determined?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... cost for purposes of leasehold surrender interest value be determined? 51.56 Section 51.56 Parks... Leasehold Surrender Interest § 51.56 How will the construction cost for purposes of leasehold surrender... false, misleading or incomplete information. [66 FR 35083, July 3, 2001] ...

  14. 36 CFR 51.56 - How will the construction cost for purposes of leasehold surrender interest value be determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... cost for purposes of leasehold surrender interest value be determined? 51.56 Section 51.56 Parks... Leasehold Surrender Interest § 51.56 How will the construction cost for purposes of leasehold surrender... false, misleading or incomplete information. [66 FR 35083, July 3, 2001] ...

  15. Green Energy in New Construction: Maximize Energy Savings and Minimize Cost

    ERIC Educational Resources Information Center

    Ventresca, Joseph

    2010-01-01

    People often use the term "green energy" to refer to alternative energy technologies. But green energy doesn't guarantee maximum energy savings at a minimum cost--a common misconception. For school business officials, green energy means getting the lowest energy bills for the lowest construction cost, which translates into maximizing green energy…

  16. Collective workload organization in confined excavation of granular media

    NASA Astrophysics Data System (ADS)

    Monaenkova, Daria; Linevich, Vadim; Goodisman, Michael A.; Goldman, Daniel I.

    2015-03-01

    Many social insects collectively construct large nests in complex substrates; such structures are often composed of narrow tunnels. The benefits of collective construction, including reduced construction costs per worker come with challenges of navigation in crowded, confined spaces. Here we study the workforce organization of groups of S. invicta fire ants creating tunnels in wet granular media. We monitor the activity levels of marked (painted) workers-defined as a number of tunnel visits over 12 hours- during initiation of tunnels. The activity levels are described by a Lorenz curve with a Gini coefficient of ~ 0 . 7 indicating that a majority of the excavation is performed by a minority of workers. We hypothesize that this workload distribution is beneficial for excavation in crowded conditions, and use a 2D cellular automata (CA) model to reproduce behaviors of the excavating ants. CA simulations reveal that tunnel construction rates decrease in groups of equally active animals compared to groups with the natural workload distribution. We use predictions of the CA model to organize collective excavation of granular material by teams of digging robots, and use the robots to test hypotheses of crowded excavation in the physical world. We acknowledge support of National Science Foundation, Physics of Living Systems division.

  17. Natural resources research and development in Lesotho using LANDSAT imagery

    NASA Technical Reports Server (NTRS)

    Jackson, A. A. (Principal Investigator)

    1976-01-01

    The author has identified the following significant results. A map of the drainage of the whole country to include at least third order streams was constructed from LANDSAT imagery. This was digitized and can be plotted at any required scale to provide base maps for other cartographic projects. A suite of programs for the interpretation of digital LANDSAT data is under development for a low cost programmable calculator. Initial output from these programs has proved to have better resolution and detail than the standard photographic products, and was to update the standard topographic map of a particular region.

  18. 24 CFR 585.306 - Designation of costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Construction management. (e) Relocation costs. (f) Legal fees. (g) Clearance and demolition. ..., rehabilitation, or new construction for the purposes of §§ 585.307, 585.309, 585.310, and 585.311. (a) Trainees...

  19. 24 CFR 585.306 - Designation of costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Construction management. (e) Relocation costs. (f) Legal fees. (g) Clearance and demolition. ..., rehabilitation, or new construction for the purposes of §§ 585.307, 585.309, 585.310, and 585.311. (a) Trainees...

  20. 24 CFR 585.306 - Designation of costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Construction management. (e) Relocation costs. (f) Legal fees. (g) Clearance and demolition. ..., rehabilitation, or new construction for the purposes of §§ 585.307, 585.309, 585.310, and 585.311. (a) Trainees...

  1. 24 CFR 585.306 - Designation of costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Construction management. (e) Relocation costs. (f) Legal fees. (g) Clearance and demolition. ..., rehabilitation, or new construction for the purposes of §§ 585.307, 585.309, 585.310, and 585.311. (a) Trainees...

  2. Evaluation of construction strategies for PCC pavement rehabilitation projects.

    DOT National Transportation Integrated Search

    2010-09-30

    This study investigated project management level solutions to optimizing resources, minimizing costs : (including user costs) and time for PCC pavement rehabilitation projects. This study extensively : evaluated the applicability of the Construction ...

  3. Biomechanical and Cost Comparisons of Near-Far and Pin-Bar Constructs.

    PubMed

    Whitney Kluk, Augusta; Zhang, Tina; Russell, Joseph P; Kim, Hyunchul; Hsieh, Adam H; O'Toole, Robert V

    2017-03-01

    Orthopedic dogma states that external fixator stiffness is improved by placing 1 pin close to the fracture and 1 as distant as possible ("near-far"). This fixator construct is thought to be less expensive than placing pins a shorter distance apart and using "pin-bar" clamps that attach pins to outriggers. The authors therefore hypothesized that the near-far construct is stiffer and less expensive. They compared mechanical stiffness and costs of near-far and pin-bar constructs commonly used for temporary external fixation of femoral shaft fractures. Their testing model simulated femoral shaft fractures in damage control situations. Fourth-generation synthetic femora (n=18) were used. The near-far construct had 2 pins that were 106 mm apart, placed 25 mm from the gap on each side of the fracture. The pin-bar construct pins were 55 mm apart, placed 40 mm from the gap. Mechanical testing was performed on a material test system machine. Stiffness was determined in the linear portion of the load-displacement curve for both constructs in 4 modes: axial compression, torsional loading, frontal plane 3-point bending, and sagittal plane 3-point bending. Costs were determined from a 2012 price guide. Compared with the near-far construct, the pin-bar construct had stiffness increased by 58% in axial compression (P<.05) and by 52% in torsional loading (P<.05). The pin-bar construct increased cost by 11%. In contrast to the authors' hypothesis and existing orthopedic dogma, the near-far construct was less stiff than the pin-bar construct and was similarly priced. Use of the pin-bar construct is mechanically and economically reasonable. [Orthopedics. 2017; 40(2):e238-e241.]. Copyright 2016, SLACK Incorporated.

  4. Exploitation and Benefits of BIM in Construction Project Management

    NASA Astrophysics Data System (ADS)

    Mesároš, Peter; Mandičák, Tomáš

    2017-10-01

    BIM is increasingly getting into the awareness in construction industry. BIM is the process of creating and data managing of the building during its life cycle. BIM became a part of management tools in modern construction companies. Construction projects have a number of participants. It means difficulty process of construction project management and a serious requirement for processing the huge amount of information including design, construction, time and cost parameters, economic efficiency and sustainability. Progressive information and communication technologies support cost management and management of construction project. One of them is Building Information Modelling. Aim of the paper is to examine the impact of BIM exploitation and benefits on construction project management in Slovak companies.

  5. Initial Costs vs. Operational Costs. A Study of Building Improvement Projects in Fourteen Schools in the School District of Greenville County, South Carolina.

    ERIC Educational Resources Information Center

    Chan, Tak Cheung

    To determine whether initial facility improvement costs were paid back by the reduced operational costs resulting from the improvement projects, this study examined the relationship between initial costs and operational costs of fourteen school buildings improved during the 1978-79 school year in Greenville County, South Carolina. With energy…

  6. The Impact of State Regulations on the Costs of Public School Construction

    ERIC Educational Resources Information Center

    Vincent, Jeffrey M.; Monkkonen, Paavo

    2010-01-01

    Spending by states and local school districts on school construction has increased dramatically over the last decade, not only because more and higher-quality schools are being built, but also because construction costs have increased by an unprecedented degree. Many states struggle to afford the new schools needed in local communities. The…

  7. Vascular access choice in incident hemodialysis patients: a decision analysis.

    PubMed

    Drew, David A; Lok, Charmaine E; Cohen, Joshua T; Wagner, Martin; Tangri, Navdeep; Weiner, Daniel E

    2015-01-01

    Hemodialysis vascular access recommendations promote arteriovenous (AV) fistulas first; however, it may not be the best approach for all hemodialysis patients, because likelihood of successful fistula placement, procedure-related and subsequent costs, and patient survival modify the optimal access choice. We performed a decision analysis evaluating AV fistula, AV graft, and central venous catheter (CVC) strategies for patients initiating hemodialysis with a CVC, a scenario occurring in over 70% of United States dialysis patients. A decision tree model was constructed to reflect progression from hemodialysis initiation. Patients were classified into one of three vascular access choices: maintain CVC, attempt fistula, or attempt graft. We explicitly modeled probabilities of primary and secondary patency for each access type, with success modified by age, sex, and diabetes. Access-specific mortality was incorporated using preexisting cohort data, including terms for age, sex, and diabetes. Costs were ascertained from the 2010 USRDS report and Medicare for procedure costs. An AV fistula attempt strategy was found to be superior to AV grafts and CVCs in regard to mortality and cost for the majority of patient characteristic combinations, especially younger men without diabetes. Women with diabetes and elderly men with diabetes had similar outcomes, regardless of access type. Overall, the advantages of an AV fistula attempt strategy lessened considerably among older patients, particularly women with diabetes, reflecting the effect of lower AV fistula success rates and lower life expectancy. These results suggest that vascular access-related outcomes may be optimized by considering individual patient characteristics. Copyright © 2015 by the American Society of Nephrology.

  8. A microcosting study of microsurgery, LINAC radiosurgery, and gamma knife radiosurgery in meningioma patients

    PubMed Central

    van Putten, Erik; Nijdam, Wideke M.; Hanssens, Patrick; Beute, Guus N.; Nowak, Peter J.; Dirven, Clemens M.; Hakkaart-van Roijen, Leona

    2010-01-01

    The aim of the present study is to determine and compare initial treatment costs of microsurgery, linear accelerator (LINAC) radiosurgery, and gamma knife radiosurgery in meningioma patients. Additionally, the follow-up costs in the first year after initial treatment were assessed. Cost analyses were performed at two neurosurgical departments in The Netherlands from the healthcare providers’ perspective. A total of 59 patients were included, of whom 18 underwent microsurgery, 15 underwent LINAC radiosurgery, and 26 underwent gamma knife radiosurgery. A standardized microcosting methodology was employed to ensure that the identified cost differences would reflect only actual cost differences. Initial treatment costs, using equipment costs per fraction, were €12,288 for microsurgery, €1,547 for LINAC radiosurgery, and €2,412 for gamma knife radiosurgery. Higher initial treatment costs for microsurgery were predominantly due to inpatient stay (€5,321) and indirect costs (€4,350). LINAC and gamma knife radiosurgery were equally expensive when equipment was valued per treatment (€2,198 and €2,412, respectively). Follow-up costs were slightly, but not significantly, higher for microsurgery compared with LINAC and gamma knife radiosurgery. Even though initial treatment costs were over five times higher for microsurgery compared with both radiosurgical treatments, our study gives indications that the relative cost difference may decrease when follow-up costs occurring during the first year after initial treatment are incorporated. This reinforces the need to consider follow-up costs after initial treatment when examining the relative costs of alternative treatments. PMID:20526795

  9. 36 CFR 223.111 - Administration of contracts in designated disaster areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... road or facility, the United States shall bear such increased construction cost if, as determined by... damages are so great that restoration, reconstruction, or construction is not practical under the cost...

  10. Construction engineering inspection direct cost survey.

    DOT National Transportation Integrated Search

    2014-07-01

    The objective of the study was to provide a rationale to Georgia Department of Transportation : (GDOT) for Direct Costs in terms of salary and wages charged by qualified independent : contractors performing Construction Engineering Inspection (CEI) s...

  11. 23 CFR 140.907 - Overhead and indirect construction costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Overhead and indirect construction costs. 140.907 Section 140.907 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES... 18276, May 23, 1988] ...

  12. 23 CFR 140.907 - Overhead and indirect construction costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Overhead and indirect construction costs. 140.907 Section 140.907 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES... 18276, May 23, 1988] ...

  13. 23 CFR 140.907 - Overhead and indirect construction costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Overhead and indirect construction costs. 140.907 Section 140.907 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES... 18276, May 23, 1988] ...

  14. Cost analysis of the built environment: the case of bike and pedestrian trials in Lincoln, Neb.

    PubMed

    Wang, Guijing; Macera, Caroline A; Scudder-Soucie, Barbara; Schmid, Tom; Pratt, Michael; Buchner, David; Heath, Gregory

    2004-04-01

    We estimated the annual cost of bike and pedestrian trails in Lincoln, Neb, using construction and maintenance costs provided by the Department of Parks and Recreation of Nebraska. We obtained the number of users of 5 trails from a 1998 census report. The annual construction cost of each trail was calculated by using 3%, 5%, and 10% discount rates for a period of useful life of 10, 30, and 50 years. The average cost per mile and per user was calculated. Trail length averaged 3.6 miles (range = 1.6-4.6 miles). Annual cost in 2002 dollars ranged from 25,762 to 248,479 (mean = 124,927; median = 171,064). The cost per mile ranged from 5735 to 54,017 (mean = 35,355; median = 37,994). The annual cost per user was 235 (range = 83-592), whereas per capita annual medical cost of inactivity was 622. Construction of trails fits a wide range of budgets and may be a viable health amenity for most communities. To increase trail cost-effectiveness, efforts to decrease cost and increase the number of users should be considered.

  15. Design Features and Commissioning of the Versatile Experiment Spherical Torus (VEST) at Seoul National University

    NASA Astrophysics Data System (ADS)

    J. Chung, K.; H. An, Y.; K. Jung, B.; Y. Lee, H.; C., Sung; S. Na, Y.; S. Hahm, T.; S. Hwang, Y.

    2013-03-01

    A new spherical torus called VEST (Versatile Experiment Spherical Torus) is designed, constructed and successfully commissioned at Seoul National University. A unique design feature of the VEST is two partial solenoid coils installed at both vertical ends of a center stack, which can provide sufficient magnetic fluxes to initiate tokamak plasmas while keeping a low aspect ratio configuration in the central region. According to initial double null merging start-up scenario using the partial solenoid coils, appropriate power supplies for driving a toroidal field coil, outer poloidal field coils, and the partial solenoid coils are fabricated and successfully commissioned. For reliable start-up, a pre-ionization system with two cost-effective homemade magnetron power supplies is also prepared. In addition, magnetic and spectroscopic diagnostics with appropriate data acquisition and control systems are well prepared for initial operation of the device. The VEST is ready for tokamak plasma operation by completing and commissioning most of the designed components.

  16. A bi-objective model for robust yard allocation scheduling for outbound containers

    NASA Astrophysics Data System (ADS)

    Liu, Changchun; Zhang, Canrong; Zheng, Li

    2017-01-01

    This article examines the yard allocation problem for outbound containers, with consideration of uncertainty factors, mainly including the arrival and operation time of calling vessels. Based on the time buffer inserting method, a bi-objective model is constructed to minimize the total operational cost and to maximize the robustness of fighting against the uncertainty. Due to the NP-hardness of the constructed model, a two-stage heuristic is developed to solve the problem. In the first stage, initial solutions are obtained by a greedy algorithm that looks n-steps ahead with the uncertainty factors set as their respective expected values; in the second stage, based on the solutions obtained in the first stage and with consideration of uncertainty factors, a neighbourhood search heuristic is employed to generate robust solutions that can fight better against the fluctuation of uncertainty factors. Finally, extensive numerical experiments are conducted to test the performance of the proposed method.

  17. Corps of Engineers’ Acquisition of Fish Hatchery Proves Costly.

    DTIC Science & Technology

    1981-09-18

    location, size, esti- mated cost, design , and construction timetables for facilities needed to meet the steelhead production requirements. To limit...hatchery "* * * is not recognized to be one of the more efficient and productive facilities in Idaho due to obvious con- straints in design , construction...agency’s decision to supply the product or service it- self because it would cost less must be supported by a comparativ , cost analysis. According to Corps

  18. Construction of road network vulnerability evaluation index based on general travel cost

    NASA Astrophysics Data System (ADS)

    Leng, Jun-qiang; Zhai, Jing; Li, Qian-wen; Zhao, Lin

    2018-03-01

    With the development of China's economy and the continuous improvement of her urban road network, the vulnerability of the urban road network has attracted increasing attention. Based on general travel cost, this work constructs the vulnerability evaluation index for the urban road network, and evaluates the vulnerability of the urban road network from the perspective of user generalised travel cost. Firstly, the generalised travel cost model is constructed based on vehicle cost, travel time, and traveller comfort. Then, the network efficiency index is selected as an evaluation index of vulnerability: the network efficiency index is composed of the traffic volume and the generalised travel cost, which are obtained from the equilibrium state of the network. In addition, the research analyses the influence of traffic capacity decrease, road section attribute value, and location of road section, on vulnerability. Finally, the vulnerability index is used to analyse the local area network of Harbin and verify its applicability.

  19. Need of risk management practice amongst bumiputera contractors in Malaysia construction industries

    NASA Astrophysics Data System (ADS)

    Syuhada Fadzil, Nur; Noor, Nurazuwa Md; Rahman, Ismail Abdul

    2017-11-01

    Malaysia construction industry has been growing continuously with double-digit growth for the past two decades. There are many issues surrounded the industry such as delay in delivery, cost overrun, quality and safety. In bumiputera contractor’s context, the literature review found that 32 issues were encountered in the construction project. These issues can be handled properly with the application of risk management. According to previous researchers, application of risk management in Malaysia construction industry is at the low level where it is implemented in traditional ways that are brainstorming and checklist. These were due to lack of knowledge, the high cost of hiring experts and avoiding extra cost. Besides that, this study also intentions to analyse the risk categories in the construction industry as well as identify risk management process to resolve the construction issues. Hence, this paper presents issues engulfed by Bumiputera contractors which can partly be resolved by applying risk management practice in carrying out the construction activity. This may inspire the contractors to apply the risk management practice in ensuring the success of their construction project.

  20. Cost-effectiveness of a package of interventions for expedited antiretroviral therapy initiation during pregnancy in Cape Town, South Africa

    PubMed Central

    ZULLIGER, Rose; BLACK, Samantha; HOLTGRAVE, David R.; CIARANELLO, Andrea L.; BEKKER, Linda–Gail; MYER, Landon

    2014-01-01

    Initiating antiretroviral therapy (ART) early in pregnancy is an important component of effective interventions to prevent the mother-to-child transmission of HIV (PMTCT). The Rapid initiation of ART in Pregnancy (RAP) program was a package of interventions to expedite ART initiation in pregnant women in Cape Town, South Africa. Retrospective, cost-effectiveness, sensitivity and threshold analyses were conducted of the RAP program to determine the cost-utility thresholds for rapid initiation of ART in pregnancy. Costs were drawn from a detailed microcosting of the program. The overall programmatic cost was US$880 per woman and the base case cost-effectiveness ratio was US$1,160 per quality-adjusted life year (QALY) saved. In threshold analyses, the RAP program remained cost-effective if mother-to-child transmission was reduced by ≥0.33%; if ≥1.76 QALY were saved with each averted perinatal infection; or if RAP-related costs were under US$4,020 per woman. The package of rapid initiation services was very cost-effective, as compared to standard services in this setting. Threshold analyses demonstrated that the intervention required minimal reductions in perinatal infections in order to be cost-effective. Interventions for the rapid initiation of ART in pregnancy hold considerable potential as a cost-effective use of limited resources for PMTCT in sub-Saharan Africa. PMID:24122044

  1. Low-cost satellite mechanical design and construction

    NASA Astrophysics Data System (ADS)

    Boisjolie-Gair, Nathaniel; Straub, Jeremy

    2017-05-01

    This paper presents a discussion of techniques for low-cost design and construction of a CubeSat mechanical structure that can serve as a basis for academic programs and a starting point for government, military and commercial large-scale sensing networks, where the cost of each node must be minimized to facilitate system affordability and lower the cost and associated risk of losing any node. Spacecraft Design plays a large role in manufacturability. An intentionally simplified mechanical design is presented which reduces machining costs, as compared to more intricate designs that were considered. Several fabrication approaches are evaluated relative to the low-cost goal.

  2. STANDARDIZED COSTS FOR WATER SUPPLY DISTRIBUTION SYSTEMS

    EPA Science Inventory

    Presented within the report are cost data for construction and operation/maintenance of domestic water distribution and transmission pipelines, domestic water pumping stations, and domestic water storage reservoirs. To allow comparison of new construction with rehabilitation of e...

  3. The cost and analysis of nonuse of cochlear implants.

    PubMed

    Raine, Christopher H; Summerfield, Quentin; Strachan, David R; Martin, Jane M; Totten, Catherine

    2008-02-01

    Analysis of the cost implications and reasons for nonuse of cochlear implants in an established cochlear implant unit. Clinical data were analyzed retrospectively to construct a table of cochlear implant use over time to identify nonuse and to suggest the reasons for this. Yorkshire Cochlear Implant Service is a tertiary referral center. Three hundred forty consecutively implanted patients from 1990 to 2005. Life table analysis showed that most children used their implant (p = 0.7 during 11 yr). However, 11 of 155 children and 2 of 185 adults became nonusers during the period of study. The 11 children stopped because of age at implant, educational placement, and family support. Two adults stopped because of psychological issues and inability to adapt to the signal. Surgical and implant costs have initial impact, with subsequent years' costs reflecting programming issues and maintenance. When considering nonuse, there are 2 effects: first, no more costs are incurred, and second, no more years of use are accumulated. Thus, nonuse reduces both costs and years. Costs of gaining a year of use as a function of time showed that there was little financial impact from the 11 children nonusers. As a ratio of "no nonuse" and observed "nonuse" in children, the ratio is 1.07 by 13 years of implantation (7%). The adult group was too few to analyze. The nonuse added 7% to the average cost. Retrospective audit identifies that patient selection by a multidisciplinary team is crucial to reducing nonuse.

  4. The cost-effectiveness of etanercept in patients with severe ankylosing spondylitis in the UK.

    PubMed

    Ara, R M; Reynolds, A V; Conway, P

    2007-08-01

    To examine the costs and benefits associated with long-term etanercept (ETN) treatment in patients with severe ankylosing spondylitis (AS) in the UK in accordance with the BSR guidelines. A mathematical model was constructed to estimate the costs and benefits associated with ETN plus non-steroidal anti-inflammatory drugs (NSAIDs) compared with NSAIDs alone. Individual patient data from Phase III RCTs was used to inform the proportion and magnitude of initial response to treatment and changes in health-related quality of life. A retrospective costing exercise on patients attending a UK secondary care rheumatology unit was used to inform disease costs. Published evidence on long-term disease progression was extrapolated over a 25-yr horizon. Uncertainty was examined using probabilistic sensitivity analyses. Over a 25-yr horizon, ETN plus NSAIDs gave 1.58 more QALYs at an additional cost of 35,978 pounds when compared with NSAID treatment alone. This equates to a central estimate of 22,700 pounds per QALY. The incremental cost per QALYs using shorter time periods were 27,600 pounds, 23,600 pounds and 22,600 pounds at 2, 5 and 15 yrs, respectively. Using a 25-yr horizon, 93% of results from the probabilistic analyses fall below a threshold of 25,000 pounds per QALY. This study demonstrates the potential cost-effectiveness of ETN plus NSAIDs compared with NSAIDs alone in patients with severe AS treated according to the BSR guidelines in the UK.

  5. Cost-Effectiveness Analysis of Surface Flow Constructed Wetlands (SFCW) for Nutrient Reduction in Drainage Discharge from Agricultural Fields in Denmark.

    PubMed

    Gachango, F G; Pedersen, S M; Kjaergaard, C

    2015-12-01

    Constructed wetlands have been proposed as cost-effective and more targeted technologies in the reduction of nitrogen and phosphorous water pollution in drainage losses from agricultural fields in Denmark. Using two pig farms and one dairy farm situated in a pumped lowland catchment as case studies, this paper explores the feasibility of implementing surface flow constructed wetlands (SFCW) based on their cost effectiveness. Sensitivity analysis is conducted by varying the cost elements of the wetlands in order to establish the most cost-effective scenario and a comparison with the existing nutrients reduction measures carried out. The analyses show that the cost effectiveness of the SFCW is higher in the drainage catchments with higher nutrient loads. The range of the cost effectiveness ratio on nitrogen reduction differs distinctively with that of catch crop measure. The study concludes that SFCW could be a better optimal nutrients reduction measure in drainage catchments characterized with higher nutrient loads.

  6. Forecasting Construction Cost Index based on visibility graph: A network approach

    NASA Astrophysics Data System (ADS)

    Zhang, Rong; Ashuri, Baabak; Shyr, Yu; Deng, Yong

    2018-03-01

    Engineering News-Record (ENR), a professional magazine in the field of global construction engineering, publishes Construction Cost Index (CCI) every month. Cost estimators and contractors assess projects, arrange budgets and prepare bids by forecasting CCI. However, fluctuations and uncertainties of CCI cause irrational estimations now and then. This paper aims at achieving more accurate predictions of CCI based on a network approach in which time series is firstly converted into a visibility graph and future values are forecasted relied on link prediction. According to the experimental results, the proposed method shows satisfactory performance since the error measures are acceptable. Compared with other methods, the proposed method is easier to implement and is able to forecast CCI with less errors. It is convinced that the proposed method is efficient to provide considerably accurate CCI predictions, which will make contributions to the construction engineering by assisting individuals and organizations in reducing costs and making project schedules.

  7. Automated Reuse of Scientific Subroutine Libraries through Deductive Synthesis

    NASA Technical Reports Server (NTRS)

    Lowry, Michael R.; Pressburger, Thomas; VanBaalen, Jeffrey; Roach, Steven

    1997-01-01

    Systematic software construction offers the potential of elevating software engineering from an art-form to an engineering discipline. The desired result is more predictable software development leading to better quality and more maintainable software. However, the overhead costs associated with the formalisms, mathematics, and methods of systematic software construction have largely precluded their adoption in real-world software development. In fact, many mainstream software development organizations, such as Microsoft, still maintain a predominantly oral culture for software development projects; which is far removed from a formalism-based culture for software development. An exception is the limited domain of safety-critical software, where the high-assuiance inherent in systematic software construction justifies the additional cost. We believe that systematic software construction will only be adopted by mainstream software development organization when the overhead costs have been greatly reduced. Two approaches to cost mitigation are reuse (amortizing costs over many applications) and automation. For the last four years, NASA Ames has funded the Amphion project, whose objective is to automate software reuse through techniques from systematic software construction. In particular, deductive program synthesis (i.e., program extraction from proofs) is used to derive a composition of software components (e.g., subroutines) that correctly implements a specification. The construction of reuse libraries of software components is the standard software engineering solution for improving software development productivity and quality.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Im, Piljae; Liu, Xiaobing

    High initial costs and lack of public awareness of ground-source heat pump (GSHP) technology are the two major barriers preventing rapid deployment of this energy-saving technology in the United States. Under the American Recovery and Reinvestment Act (ARRA), 26 GSHP projects have been competitively selected and carried out to demonstrate the benefits of GSHP systems and innovative technologies for cost reduction and/or performance improvement. This paper highlights the findings of a case study of one of the ARRA-funded GSHP demonstration projects, a ground-source variable refrigerant flow (GS-VRF) system installed at the Human Health Building at Oakland University in Rochester, Michigan.more » This case study is based on the analysis of measured performance data, maintenance records, construction costs, and simulations of the energy consumption of conventional central heating, ventilation, and air-conditioning (HVAC) systems providing the same level of space conditioning as the demonstrated GS-VRF system. The evaluated performance metrics include the energy efficiency of the heat pump equipment and the overall GS-VRF system, pumping performance, energy savings, carbon emission reductions, and cost-effectiveness of the GS-VRF system compared with conventional HVAC systems. This case study also identified opportunities for reducing uncertainties in the performance evaluation, improving the operational efficiency, and reducing the installed cost of similar GSHP systems in the future.« less

  9. Construction of VLCC marine oil storage cost index system

    NASA Astrophysics Data System (ADS)

    Li, Yuan; Li, Yule; Lu, Jinshu; Wu, Wenfeng; Zhu, Faxin; Chen, Tian; Qin, Beichen

    2018-04-01

    VLCC as the research object, the basic knowledge of VLCC is summarized. According to the phenomenon that VLCC is applied to offshore oil storage gradually, this paper applies the theoretical analysis method to analyze the excess capacity from VLCC, the drop of oil price, the aging VLCC is more suitable for offshore storage The paper analyzes the reason of VLCC offshore oil storage from three aspects, analyzes the cost of VLCC offshore storage from the aspects of manpower cost and shipping cost, and constructs the cost index system of VLCC offshore oil storage.

  10. Residential Cold Climate Heat Pump (CCHP) w/Variable Speed Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Messmer, Craig S.

    2016-09-30

    This report summarizes the results of a three year program awarded to Unico, Inc. to commercialize a residential cold climate heat pump. Several designs were investigated. Compressors were selected using analysis from Oakridge National Laboratories followed by prototype construction and lab testing in a specially built environmental chamber capable of reaching -30°F. The initial design utilized two variable speed compressors in series with very good capacity results and acceptable efficiency at very cold temperatures. The design was then modified to reduce cost and complexity by redesigning the system using three dual-stage compressors: two in parallel followed by one in series.more » Extensive testing found significant challenge with oil management, reliability, weight and cost which prevented the system from being fully commercialized. Further analysis of other conceptual designs indicated that these challenges could be overcome in the future.« less

  11. Assessment of grid optimisation measures for the German transmission grid using open source grid data

    NASA Astrophysics Data System (ADS)

    Böing, F.; Murmann, A.; Pellinger, C.; Bruckmeier, A.; Kern, T.; Mongin, T.

    2018-02-01

    The expansion of capacities in the German transmission grid is a necessity for further integration of renewable energy sources into the electricity sector. In this paper, the grid optimisation measures ‘Overhead Line Monitoring’, ‘Power-to-Heat’ and ‘Demand Response in the Industry’ are evaluated and compared against conventional grid expansion for the year 2030. Initially, the methodical approach of the simulation model is presented and detailed descriptions of the grid model and the used grid data, which partly originates from open-source platforms, are provided. Further, this paper explains how ‘Curtailment’ and ‘Redispatch’ can be reduced by implementing grid optimisation measures and how the depreciation of economic costs can be determined considering construction costs. The developed simulations show that the conventional grid expansion is more efficient and implies more grid relieving effects than the evaluated grid optimisation measures.

  12. The 3D Elevation Program: summary for Connecticut

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  13. A multi-period optimization model for energy planning with CO(2) emission consideration.

    PubMed

    Mirzaesmaeeli, H; Elkamel, A; Douglas, P L; Croiset, E; Gupta, M

    2010-05-01

    A novel deterministic multi-period mixed-integer linear programming (MILP) model for the power generation planning of electric systems is described and evaluated in this paper. The model is developed with the objective of determining the optimal mix of energy supply sources and pollutant mitigation options that meet a specified electricity demand and CO(2) emission targets at minimum cost. Several time-dependent parameters are included in the model formulation; they include forecasted energy demand, fuel price variability, construction lead time, conservation initiatives, and increase in fixed operational and maintenance costs over time. The developed model is applied to two case studies. The objective of the case studies is to examine the economical, structural, and environmental effects that would result if the electricity sector was required to reduce its CO(2) emissions to a specified limit. Copyright 2009 Elsevier Ltd. All rights reserved.

  14. A precise goniometer/tensiometer using a low cost single-board computer

    NASA Astrophysics Data System (ADS)

    Favier, Benoit; Chamakos, Nikolaos T.; Papathanasiou, Athanasios G.

    2017-12-01

    Measuring the surface tension and the Young contact angle of a droplet is extremely important for many industrial applications. Here, considering the booming interest for small and cheap but precise experimental instruments, we have constructed a low-cost contact angle goniometer/tensiometer, based on a single-board computer (Raspberry Pi). The device runs an axisymmetric drop shape analysis (ADSA) algorithm written in Python. The code, here named DropToolKit, was developed in-house. We initially present the mathematical framework of our algorithm and then we validate our software tool against other well-established ADSA packages, including the commercial ramé-hart DROPimage Advanced as well as the DropAnalysis plugin in ImageJ. After successfully testing for various combinations of liquids and solid surfaces, we concluded that our prototype device would be highly beneficial for industrial applications as well as for scientific research in wetting phenomena compared to the commercial solutions.

  15. The 3D Elevation Program: summary for Mississippi

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  16. The 3D Elevation Program: summary for Georgia

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  17. The 3D Elevation Program: summary for Iowa

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  18. The 3D Elevation Program: summary for Oklahoma

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  19. The 3D Elevation Program: summary for Kansas

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  20. The 3D Elevation Program: summary for Nevada

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  1. The 3D Elevation Program: summary for Illinois

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  2. The 3D Elevation Program: summary for Colorado

    USGS Publications Warehouse

    Carswell, William J.

    2013-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  3. The 3D Elevation Program: summary for Utah

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  4. The 3D Elevation Program: summary for Delaware

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  5. The 3D Elevation Program: summary for Massachusetts

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  6. The 3D Elevation Program: summary for West Virginia

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  7. The 3D Elevation Program: summary for South Carolina

    USGS Publications Warehouse

    Carswell, William

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  8. The 3D Elevation Program: summary for North Carolina

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the use community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  9. The 3D Elevation Program: summary for South Dakota

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  10. The 3D Elevation Program: Summary for New Jersey

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  11. The 3D Elevation Program: summary for Washington

    USGS Publications Warehouse

    Carswell, William J.

    2013-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  12. The 3D Elevation Program: summary for New Mexico

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 (table 1) for the conterminous United States and quality level 5 ifsar data (table 1) for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  13. The 3D Elevation Program: summary for Wyoming

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  14. The 3D Elevation Program: summary for Arizona

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  15. The 3D Elevation Program: summary for New Hampshire

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  16. The 3D Elevation Program: summary for Pennsylvania

    USGS Publications Warehouse

    Carswell, William J.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  17. The 3D Elevation Program: summary for Arkansas

    USGS Publications Warehouse

    Carswell, William J.

    2014-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  18. Simulation of value stream mapping and discrete optimization of energy consumption in modular construction

    NASA Astrophysics Data System (ADS)

    Chowdhury, Md Mukul

    With the increased practice of modularization and prefabrication, the construction industry gained the benefits of quality management, improved completion time, reduced site disruption and vehicular traffic, and improved overall safety and security. Whereas industrialized construction methods, such as modular and manufactured buildings, have evolved over decades, core techniques used in prefabrication plants vary only slightly from those employed in traditional site-built construction. With a focus on energy and cost efficient modular construction, this research presents the development of a simulation, measurement and optimization system for energy consumption in the manufacturing process of modular construction. The system is based on Lean Six Sigma principles and loosely coupled system operation to identify the non-value adding tasks and possible causes of low energy efficiency. The proposed system will also include visualization functions for demonstration of energy consumption in modular construction. The benefits of implementing this system include a reduction in the energy consumption in production cost, decrease of energy cost in the production of lean-modular construction, and increase profit. In addition, the visualization functions will provide detailed information about energy efficiency and operation flexibility in modular construction. A case study is presented to validate the reliability of the system.

  19. The design and construction of a cost-efficient confocal laser scanning microscope

    NASA Astrophysics Data System (ADS)

    Xi, Peng; Rajwa, Bartlomiej; Jones, James T.; Robinson, J. Paul

    2007-03-01

    The optical dissection ability of confocal microscopy makes it a powerful tool for biological materials. However, the cost and complexity of confocal scanning laser microscopy hinders its wide application in education. We describe the construction of a simplified confocal scanning laser microscope and demonstrate three-dimensional projection based on cost-efficient commercial hardware, together with available open source software.

  20. Rapid Leaf Deployment Strategies in a Deciduous Savanna

    PubMed Central

    2016-01-01

    Deciduous plants avoid the costs of maintaining leaves in the unfavourable season, but carry the costs of constructing new leaves every year. Deciduousness is therefore expected in ecological situations with pronounced seasonality and low costs of leaf construction. In our study system, a seasonally dry tropical savanna, many trees are deciduous, suggesting that leaf construction costs must be low. Previous studies have, however, shown that nitrogen is limiting in this system, suggesting that leaf construction costs are high. Here we examine this conundrum using a time series of soil moisture availability, leaf phenology and nitrogen distribution in the tree canopy to illustrate how trees resorb nitrogen before leaf abscission and use stored reserves of nitrogen and carbon to construct new leaves at the onset of the growing season. Our results show that trees deployed leaves shortly before and in anticipation of the first rains with its associated pulse of nitrogen mineralisation. Our results also show that trees rapidly constructed a full canopy of leaves within two weeks of the first rains. We detected an increase in leaf nitrogen content that corresponded with the first rains and with the movement of nitrogen to more distal branches, suggesting that stored nitrogen reserves are used to construct leaves. Furthermore the stable carbon isotope ratios (δ13C) of these leaves suggest the use of stored carbon for leaf construction. Our findings suggest that the early deployment of leaves using stored nitrogen and carbon reserves is a strategy that is integrally linked with the onset of the first rains. This strategy may confer a competitive advantage over species that deploy leaves at or after the onset of the rains. PMID:27310398

  1. Highway construction cost comparison survey : final report

    DOT National Transportation Integrated Search

    2002-04-01

    Over the past few years the Washington State Department of Transportation (WSDOT) has been asked numerous questions related to the cost of highway construction in Washington State as compared to other states. In order to address these questions, WSDO...

  2. 10 CFR 609.12 - Project Costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

  3. Do environmental regulations increase construction costs for federal aid highways? A statistical experiment

    DOT National Transportation Integrated Search

    1999-05-01

    This paper uses Federal Aid Highway program information for 1990 to 1994 to define a natural experiment that evaluates whether compliance with federal environmental regulations increases construction costs. This is accomplished by considering whether...

  4. 10 CFR 609.12 - Project Costs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

  5. 10 CFR 609.12 - Project Costs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

  6. 10 CFR 609.12 - Project Costs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

  7. 10 CFR 609.12 - Project Costs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

  8. Improvements to the construction of binary black hole initial data

    NASA Astrophysics Data System (ADS)

    Ossokine, Serguei; Foucart, Francois; Pfeiffer, Harald P.; Boyle, Michael; Szilágyi, Béla

    2015-12-01

    Construction of binary black hole initial data is a prerequisite for numerical evolutions of binary black holes. This paper reports improvements to the binary black hole initial data solver in the spectral Einstein code, to allow robust construction of initial data for mass-ratio above 10:1, and for dimensionless black hole spins above 0.9, while improving efficiency for lower mass-ratios and spins. We implement a more flexible domain decomposition, adaptive mesh refinement and an updated method for choosing free parameters. We also introduce a new method to control and eliminate residual linear momentum in initial data for precessing systems, and demonstrate that it eliminates gravitational mode mixing during the evolution. Finally, the new code is applied to construct initial data for hyperbolic scattering and for binaries with very small separation.

  9. Medical Image Segmentation by Combining Graph Cut and Oriented Active Appearance Models

    PubMed Central

    Chen, Xinjian; Udupa, Jayaram K.; Bağcı, Ulaş; Zhuge, Ying; Yao, Jianhua

    2017-01-01

    In this paper, we propose a novel 3D segmentation method based on the effective combination of the active appearance model (AAM), live wire (LW), and graph cut (GC). The proposed method consists of three main parts: model building, initialization, and segmentation. In the model building part, we construct the AAM and train the LW cost function and GC parameters. In the initialization part, a novel algorithm is proposed for improving the conventional AAM matching method, which effectively combines the AAM and LW method, resulting in Oriented AAM (OAAM). A multi-object strategy is utilized to help in object initialization. We employ a pseudo-3D initialization strategy, and segment the organs slice by slice via multi-object OAAM method. For the segmentation part, a 3D shape constrained GC method is proposed. The object shape generated from the initialization step is integrated into the GC cost computation, and an iterative GC-OAAM method is used for object delineation. The proposed method was tested in segmenting the liver, kidneys, and spleen on a clinical CT dataset and also tested on the MICCAI 2007 grand challenge for liver segmentation training dataset. The results show the following: (a) An overall segmentation accuracy of true positive volume fraction (TPVF) > 94.3%, false positive volume fraction (FPVF) < 0.2% can be achieved. (b) The initialization performance can be improved by combining AAM and LW. (c) The multi-object strategy greatly facilitates the initialization. (d) Compared to the traditional 3D AAM method, the pseudo 3D OAAM method achieves comparable performance while running 12 times faster. (e) The performance of proposed method is comparable to the state of the art liver segmentation algorithm. The executable version of 3D shape constrained GC with user interface can be downloaded from website http://xinjianchen.wordpress.com/research/. PMID:22311862

  10. Relative Economy of Different Methods of Airplane Construction

    NASA Technical Reports Server (NTRS)

    Herrmann, H

    1931-01-01

    A comparison of the relative economy of airplane construction shows that monoplanes are cheaper than biplanes; that all-metal construction is much more expensive than mixed construction; that multi-engine airplanes are more expensive than single-engine types of the same carrying capacity and speed;that the cost of airplanes is materially reduced by increasing their size without increasing the number of engines. The greatest economy usually coincides with the best aerodynamic and static conditions and the cost is always increased by safety requirements.

  11. Modelling the resource implications and budget impact of managing cow milk allergy in Australia.

    PubMed

    Guest, J F; Nagy, E

    2009-02-01

    To estimate the resource implications and budget impact of current clinical practice for managing cow milk allergy (CMA) in Australia, from the perspective of the publicly funded healthcare system. A decision model was constructed using published clinical outcomes and clinician-derived resource utilisation estimates. The model was used to estimate the expected 6-monthly levels of healthcare resource use and corresponding costs attributable to managing 6150 new CMA sufferers following referral to a specialist. The expected 6-monthly costs of managing 6150 newly-diagnosed infants with CMA following referral to a specialist was an estimated (Australian dollars, AU$) AU$6.5 million at 2006/07 prices. Clinical nutrition preparations were found to be the primary cost driver accounting for 62% of the total 6-monthly cost and clinician visits were the secondary cost driver accounting for up to a further 28% of the total 6-monthly cost. Sensitivity analysis showed there would be fewer visits to hospital-based paediatric gastroenterologists and paediatric immunologists/allergists if all newly-diagnosed patients were prescribed an amino acid formula (AAF) following referral to a specialist, instead of being managed according to current practice. CMA imposes a substantial burden on the publicly funded healthcare system in Australia. However, using an AAF as the initial treatment for CMA can potentially release limited hospital resources for alternative use within the paediatric healthcare system.

  12. Construction cost impacts related to manpower, material, and equipment factors in contractor firms perspective

    NASA Astrophysics Data System (ADS)

    Husin, Saiful; Abdullah, Riza, Medyan; Afifuddin, Mochammad

    2017-11-01

    Risk can be defined as consequences which possible happened inscrutably. Although an activity has planned as good as possible, but it keep contains uncertainty. Implementation of construction project was encountering various risk impacts from a number of risk factors. This study was intended to analyze the impacts of construction cost to for contractor firms as construction project executor related to the factors of manpower, material and equipment. The study was using data obtained from questionnaires distributed to 15 large qualification contractor firms. The period of study classified into conflict period (2000-2004), post tsunami disaster rehabilitation and reconstruction period (2005-2009), and post rehabilitation and reconstruction period (2010-present). The statistical analysis of severity index and variance used to analyze the data. The three risk factors reviewed generally affected the cost in a medium impact. The high impact occurred in minor variables, which are `increase in material prices', `theft of materials', and `the fuel scarcity'. In overall, the three risk factors and the observed period contributed significant impact on construction costs.

  13. A cost-effectiveness comparison between early surgery and non-surgical approach for incidental papillary thyroid microcarcinoma.

    PubMed

    Lang, Brian Hung-Hin; Wong, Carlos K H

    2015-09-01

    The issue of whether all incidental papillary thyroid microcarcinoma (PTMC) should be managed by early surgery (ES) has been questioned and there is a growing acceptance that a non-surgical approach (NSA) might be more appropriate. We conducted a cost-effectiveness analysis comparing the two strategies in managing incidental PTMC. Our base case was a hypothetical 40-year-old female diagnosed with a unifocal intra-thyroidal 9 mm PTMC. The PTMC was considered suitable for either strategy. A Markov decision tree model was constructed to compare the estimated cost-effectiveness between ES and NSA after 20 years. Outcome probabilities, utilities and costs were derived from the literature. The threshold for cost-effectiveness was set at USD 50,000/quality-adjusted life year (QALY). A further analysis was done for patients < 40 and ≥ 40 years. Sensitivity and threshold analyses were used to examine model uncertainty. Each patient who adopted NSA over ES cost an extra USD 682.54 but gained an additional 0.260 QALY. NSA was cost saving (i.e. less costly and more effective) up to 16 years from diagnosis and remained cost-effective from 17 years onward. In the sensitivity analysis, NSA remained cost-effective regardless of patient age (< 40 and ≥ 40 years), complications, rates of progression, year cycle and discount rate. In the threshold analysis, none of the scenarios that could have changed the conclusion appeared clinically likely. For a selected group of incidental PTMC, adopting NSA was not only cost saving in the initial 16 years but also remained cost effective thereafter. This was irrespective of patient age, complication rate or rate of PTMC progression. © 2015 European Society of Endocrinology.

  14. 36 CFR 51.57 - How does a concessioner request arbitration of the construction cost of a capital improvement?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of the Director's determination of construction cost under § 51.56. The arbitration procedures are... improvement will be binding on the concessioner and the Director. [66 FR 35083, July 3, 2001] ...

  15. 36 CFR 51.57 - How does a concessioner request arbitration of the construction cost of a capital improvement?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of the Director's determination of construction cost under § 51.56. The arbitration procedures are... improvement will be binding on the concessioner and the Director. [66 FR 35083, July 3, 2001] ...

  16. Analysis of user waiting costs for construction projects on Louisiana's interstate highway system : final report.

    DOT National Transportation Integrated Search

    2003-04-01

    The Louisiana Department of Transportation and Development (LADOTD) is interested in applying the Federal Highway Administration=s (FHWA) life cycle cost analysis procedures and model to large roadway construction, maintenance, and rehabilitation pro...

  17. Construction costs, payback times, and the leaf economics of carnivorous plants.

    PubMed

    Karagatzides, Jim D; Ellison, Aaron M

    2009-09-01

    Understanding how different plant species and functional types "invest" carbon and nutrients is a major goal of plant ecologists. Two measures of such investments are "construction costs" (carbon needed to produce each gram of tissue) and associated "payback times" for photosynthesis to recover construction costs. These measurements integrate among traits used to assess leaf-trait scaling relationships. Carnivorous plants are model systems for examining mechanisms of leaf-trait coordination, but no studies have measured simultaneously construction costs of carnivorous traps and their photosynthetic rates to determine payback times of traps. We measured mass-based construction costs (CC(mass)) and photosynthesis (A(mass)) for traps, leaves, roots, and rhizomes of 15 carnivorous plant species grown under greenhouse conditions. There were highly significant differences among species in CC(mass) for each structure. Mean CC(mass) of carnivorous traps (1.14 ± 0.24 g glucose/g dry mass) was significantly lower than CC(mass) of leaves of 267 noncarnivorous plant species (1.47 ± 0.17), but all carnivorous plants examined had very low A(mass) and thus, long payback times (495-1551 h). Our results provide the first clear estimates of the marginal benefits of botanical carnivory and place carnivorous plants at the "slow and tough" end of the universal spectrum of leaf traits.

  18. Beamed Energy and the Economics of Space Based Solar Power

    NASA Astrophysics Data System (ADS)

    Keith Henson, H.

    2010-05-01

    For space based solar power to replace fossil fuel, it must sell for 1-2 cents per kWh. To reach this sales price requires a launch cost to GEO of ˜100/kg. Proposed to reach this cost figure at 100 tonne/hour are two stages to GEO where a Skylon-rocket-plane first stage provides five km/sec and a laser stage provides 6.64 km/sec. The combination appears to reduce the cost to GEO to under 100/kg at a materials flow rate of ˜1 million tonnes per year, enough to initially construct 200 GW per year of power satellites. An extended Pro Forma business case indicates that peak investment to profitability might be ˜65 B. Over a 25-year period, production rises to two TW per year to undercut and replace most other sources of energy. Energy on this scale solves other supply problems such as water and liquid fuels. It could even allow removal of CO2 from the air and storage of carbon as synthetic oil in empty oil fields.

  19. Evaluation of selected chemical processes for production of low-cost silicon. Quarterly progress report, 15 Dec 1975--31 Mar 1976

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blocher, J.M. Jr; Browning, M.F.; Wilson, W.J.

    1976-04-08

    Plant construction costs and manufacturing costs were estimmated for the production of solar-grade silicon by the reduction of silicon tetrachloride in a fluidized bed of seed particles, and several modifications of the iodide process using either thermal decomposition on heated filaments (rods) or hydrogen reduction in a fluidized bed of seed particles. Energy consumption data for the zinc reduction process and each of the iodide process options are given and all appear to be acceptable from the standpoint of energy pay back. Information is presented on the experimental zinc reduction of SiCl4 and electrolytic recovery of zinc from ZnCl2. Allmore » of the experimental work performed thus far has supported the initial assumption as to technical feasibility of producing semiconductor silicon by the zinc reduction or iodide processes proposed. The results of a more thorough thermodynamic evaluation of the iodination of silicon oxide/carbon mixtures are presented which explain apparent inconsistencies in an earlier cursory examination of the system.« less

  20. Low Cost Equipment for Science and Technology Education. A Resource Document on Low Cost Equipment That You Can Make and Use.

    ERIC Educational Resources Information Center

    Lowe, N. K., Ed.

    This document provides technical information and simple instructions for constructing 84 different pieces of science equipment. Each entry includes: (1) name of item; (2) purpose of the equipment; (3) person who submitted the information; (4) line drawing of prototype; (5) list of low-cost materials needed; (6) construction procedures; (7)…

  1. Cost of and soil loss on "minimum-standard" forest truck roads constructed in the central Appalachians

    Treesearch

    J. N. Kochenderfer; G. W. Wendel; H. Clay Smith

    1984-01-01

    A "minimum-standard" forest truck road that provides efficient and environmentally acceptable access for several forest activities is described. Cost data are presented for eight of these roads constructed in the central Appalachians. The average cost per mile excluding gravel was $8,119. The range was $5,048 to $14,424. Soil loss was measured from several...

  2. Estimating procedure for major highway construction bid item cost : final report.

    DOT National Transportation Integrated Search

    1978-06-01

    The present procedure for estimating construction bid item cost makes use of the quarterly weighted average unit price report coupled with engineering judgement. The limitation to this method is that this report format provides only the lowest bid da...

  3. Economic evaluation of HIV pre-exposure prophylaxis among men-who-have-sex-with-men in England in 2016.

    PubMed

    Ong, Koh Jun; Desai, Sarika; Field, Nigel; Desai, Monica; Nardone, Anthony; van Hoek, Albert Jan; Gill, Owen Noel

    2017-10-01

    Clinical effectiveness of pre-exposure prophylaxis (PrEP) for preventing HIV acquisition in men who have sex with men (MSM) at high HIV risk is established. A static decision analytical model was constructed to inform policy prioritisation in England around cost-effectiveness and budgetary impact of a PrEP programme covering 5,000 MSM during an initial high-risk period. National genitourinary medicine clinic surveillance data informed key HIV risk assumptions. Pragmatic large-scale implementation scenarios were explored. At 86% effectiveness, PrEP given to 5,000 MSM at 3.3 per 100 person-years annual HIV incidence, assuming risk compensation (20% HIV incidence increase), averted 118 HIV infections over remaining lifetimes and was cost saving. Lower effectiveness (64%) gave an incremental cost-effectiveness ratio of + GBP 23,500 (EUR 32,000) per quality-adjusted life year (QALY) gained. Investment of GBP 26.9 million (EUR 36.6 million) in year-1 breaks even anywhere from year-23 (86% effectiveness) to year-33 (64% effectiveness). PrEP cost-effectiveness was highly sensitive to year-1 HIV incidence, PrEP adherence/effectiveness, and antiretroviral drug costs. There is much uncertainty around HIV incidence in those given PrEP and adherence/effectiveness, especially under programme scale-up. Substantially reduced PrEP drug costs are needed to give the necessary assurance of cost-effectiveness, and for an affordable public health programme of sufficient size.

  4. Awareness of BIM adoption in Brunei

    NASA Astrophysics Data System (ADS)

    Rahman, Md Motiar

    2017-09-01

    Building Information Modelling (BIM) is getting increased attention day-by-day due to its many benefits, including clash detection, collaboration between contract parties, visualization future structure, optimized schedule and project control, waste control, design documentation, and harmonized facilities management. As such, many countries have already adopted BIM, and many other countries are exploring the potential of adopting it. However, it is still relatively new and unknown to some other countries like Brunei. This study was therefore undertaken to generate and/or gauge the awareness of Brunei construction industry participants, targeting adoption of BIM, through a structured questionnaire survey. Responses from 90 industry participants reveal that Brunei Construction industry is not well aware of BIM, lack the required technical knowledge and application in construction, and cost involvement. They are unsure about the potential benefits and barriers to implementing BIM. However, respondents are hopeful that BIM can bring the required changes in construction, willing to adopt BIM, expects cliental support with initial investment for its adoption, and believe that BIM is the future of construction project information management. On the whole, private sector was seen to be more aware on BIM than public sector. The study outcomes are expected to provide the policy makers a first-hand information on the industry awareness on BIM, which in turn help them for further exploration / examination and to design any action plan and guidelines for BIM adoption.

  5. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerrigan, P.

    2014-03-01

    Building Science Corporation (BSC) worked directly with the David Weekley Homes - Houston division to develop a cost-effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses in preparation for the upcoming code changes in 2015. This research project addressed the following questions: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences?more » 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost?« less

  6. A simulation model of hospital management based on cost accounting analysis according to disease.

    PubMed

    Tanaka, Koji; Sato, Junzo; Guo, Jinqiu; Takada, Akira; Yoshihara, Hiroyuki

    2004-12-01

    Since a little before 2000, hospital cost accounting has been increasingly performed at Japanese national university hospitals. At Kumamoto University Hospital, for instance, departmental costs have been analyzed since 2000. And, since 2003, the cost balance has been obtained according to certain diseases for the preparation of Diagnosis-Related Groups and Prospective Payment System. On the basis of these experiences, we have constructed a simulation model of hospital management. This program has worked correctly at repeated trials and with satisfactory speed. Although there has been room for improvement of detailed accounts and cost accounting engine, the basic model has proved satisfactory. We have constructed a hospital management model based on the financial data of an existing hospital. We will later improve this program from the viewpoint of construction and using more various data of hospital management. A prospective outlook may be obtained for the practical application of this hospital management model.

  7. Electron-phonon thermalization in a scalable method for real-time quantum dynamics

    NASA Astrophysics Data System (ADS)

    Rizzi, Valerio; Todorov, Tchavdar N.; Kohanoff, Jorge J.; Correa, Alfredo A.

    2016-01-01

    We present a quantum simulation method that follows the dynamics of out-of-equilibrium many-body systems of electrons and oscillators in real time. Its cost is linear in the number of oscillators and it can probe time scales from attoseconds to hundreds of picoseconds. Contrary to Ehrenfest dynamics, it can thermalize starting from a variety of initial conditions, including electronic population inversion. While an electronic temperature can be defined in terms of a nonequilibrium entropy, a Fermi-Dirac distribution in general emerges only after thermalization. These results can be used to construct a kinetic model of electron-phonon equilibration based on the explicit quantum dynamics.

  8. Early versus late parenteral nutrition in ICU patients: cost analysis of the EPaNIC trial

    PubMed Central

    2012-01-01

    Introduction The EPaNIC randomized controlled multicentre trial showed that postponing initiation of parenteral nutrition (PN) in ICU-patients to beyond the first week (Late-PN) enhanced recovery, as compared with Early-PN. This was mediated by fewer infections, accelerated recovery from organ failure and reduced duration of hospitalization. Now, the trial's preplanned cost analysis (N = 4640) from the Belgian healthcare payers' perspective is reported. Methods Cost data were retrieved from individual patient invoices. Undiscounted total healthcare costs were calculated for the index hospital stay. A cost tree based on acquisition of new infections and on prolonged length-of-stay was constructed. Contribution of 8 cost categories to total hospitalization costs was analyzed. The origin of drug costs was clarified in detail through the Anatomical Therapeutic Chemical (ATC) classification system. The potential impact of Early-PN on total hospitalization costs in other healthcare systems was explored in a sensitivity analysis. Results ICU-patients developing new infection (24.4%) were responsible for 42.7% of total costs, while ICU-patients staying beyond one week (24.3%) accounted for 43.3% of total costs. Pharmacy-related costs represented 30% of total hospitalization costs and were increased by Early-PN (+608.00 EUR/patient, p = 0.01). Notably, costs for ATC-J (anti-infective agents) (+227.00 EUR/patient, p = 0.02) and ATC-B (comprising PN) (+220.00 EUR/patient, p = 0.006) drugs were increased by Early-PN. Sensitivity analysis revealed a mean total cost increase of 1,210.00 EUR/patient (p = 0.02) by Early-PN, when incorporating the full PN costs. Conclusions The increased costs by Early-PN were mainly pharmacy-related and explained by higher expenditures for PN and anti-infective agents. The use of Early-PN in critically ill patients can thus not be recommended for both clinical (no benefit) and cost-related reasons. Trial registration ClinicalTrials.gov NCT00512122. PMID:22632574

  9. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2010-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  10. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2011-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  11. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2012-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  12. New Norwegian HSE standard for the offshore industry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huse, J.R.

    1996-12-31

    NORSOK (The competitive standing of the Norwegian offshore sector) is the Norwegian industry initiative to add value, reduce cost and lead time and remove unnecessary activities in offshore field developments and operations. The NORSOK standards are developed by the Norwegian petroleum industry as a part of the NORSOK initiative and are jointly issued by the Norwegian Oil Industry Association and the Federation of Norwegian Engineering Industries. The purpose of the industry standard is to replace the individual oil company specifications for use in existing and future petroleum industry developments, subject to the individual company`s review and application. The NORSOK Health,more » Safety and Environment (HSE) standards covers: Technical Safety, Working Environment, Environmental Care, HSE during Construction. The standards are now being used in ongoing offshore development projects, and the experience with standards shows that the principle aim is being met. The development of standards continues, implementing experience gained.« less

  13. Fuel weight and removal costs in fuel-break construction

    Treesearch

    James L. Murphy

    1966-01-01

    Three major fuel types were sampled during fuel-break construction on the west side of the Sierra Nevada, California. Fuel weight per acre ranged from 12.2. to 420.6 tons per acre on average. Fuel-break construction removed 27.9 to 40.5 percent of teh total fuel; costs ranged from $141.29 to $148.38 per acre and $1.16 to $4.43 per ton.

  14. 1980 Directory of Experts on Organization and Management of Construction/CIB W-65 Commission.

    DTIC Science & Technology

    1981-02-02

    7a t i onai I F ran, Ton I a tor N1anagernen t of Con strin t ion The,,,a uruts Com p iIa t i 4- 65 BIOGRAPH I C INFORMAIION PORN ,- CI.ogclier, Robc...Construction Cost Analysis of Cost-Flow Curves in Construction Unproductive Time in Building Operations Video Tape Recording for Site Studies optimization of

  15. Riverine based eco-tourism: Trinity River non-market benefits estimates

    USGS Publications Warehouse

    Douglas, A.J.; Taylor, J.G.

    1998-01-01

    California's Central Valley Project (CVP) was approved by voters in a statewide referendum in 1933. CVP referendum approval initiated funding for construction of important water development projects that had far reaching effects on regional water supplies. The construction of Trinity Dam in 1963 and the subsequent transbasin diversion of Trinity River flow was one of several CVP projects that had noteworthy adverse environmental and regional economic impacts. The Trinity River is the largest tributary of the Klamath River, and has its headwaters in the Trinity Alps of north-central California. After the construction of Trinity Dam in 1963, 90% of the Trinity River flow at Lewiston was moved to the Sacramento River via the Clear Creek Tunnel. Before 1963, the Trinity River was a major recreation resource of Northern California. The loss of streamflow has had a marked adverse impact on Trinity River-related recreation activities and the size and robustness of Trinity River salmon, steelhead, shad, and sturgeon runs. Trinity River water produces hydropower during its transit via Bureau of Reclamation canals and pumps to the northern San Joaquin Valley, where it is used for irrigated agriculture. The benefits provided by Trinity River instream flow-related environmental amenities were estimated with the travel cost method (TCM). Trinity River non-market benefits are about $406 million per annum, while the social cost of sending water down the Trinity River ranges from $17 to $42 million per annum, depending on the exact flow. We also discuss the relative magnitude of Trinity River survey data contingent value method (CVM) benefits estimates.

  16. Potential implementation of light steel housing system for affordable housing project in Malaysia

    NASA Astrophysics Data System (ADS)

    Saikah, M.; Kasim, N.; Zainal, R.; Sarpin, N.; Rahim, M. H. I. A.

    2017-11-01

    An unparalleled number between housing demand and housing supply in Malaysia has increased the housing prices, which gives consequences to the homeownership issue. One way to reduce the housing price is by faster increase the number of affordable housing, but the construction sector faces difficulties in delivering as expected number by using conventional and current industrialised building system (IBS) due to the issue related high project cost, time and labour. Therefore, light steel housing (LSH) system as one of another type of IBS method can be utilised in housing construction project. This method can replace the conventional method that was currently used in the construction of affordable housing project. The objectives of this study are to identify the potential of LSH and influencing factors of system implementation. This is an initial stage to review the previous study related to LSH implementation in developed and developing countries. The previous study will be analysed regarding advantages and disadvantages of LSH and factors that influence the implementation of the system. Based on the literature review it is expected to define the potential and influencing factors of the LSH system. The findings are meaningful in framing and enhance construction housing method of an affordable housing project in Malaysia.

  17. Performance and cost evaluation of constructed wetland for domestic waste water treatment.

    PubMed

    Deeptha, V T; Sudarsan, J S; Baskar, G

    2015-09-01

    Root zone treatment through constructed wetlands is an engineered method of purifying wastewater. The aim of the present research was to study the potential of wetland plants Phragmites and Typha in treatment of wastewater and to compare the cost of constructed wetlands with that of conventional treatment systems. A pilot wetland unit of size 2x1x0.9 m was constructed in the campus. 3x3 rows of plants were transplanted into the pilot unit and subjected to wastewater from the hostels and other campus buildings. The raw wastewater and treated wastewater were collected periodically and tested for Total nitrogen (TN),Total Phosphorous (TP), Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD). It was observed that this pilot unit reduced the concentrations of TN, TP, BOD and COD by 76, 73, 83 and 86%, respectively, on an average. Root zone system achieved standards for tertiary treatment with low operating costs, low maintenance costs, enhance the landscape, provide a natural habitat for birds, and did not emit any odour.

  18. Modeling the clinical and economic implications of obesity using microsimulation.

    PubMed

    Su, W; Huang, J; Chen, F; Iacobucci, W; Mocarski, M; Dall, T M; Perreault, L

    2015-01-01

    The obesity epidemic has raised considerable public health concerns, but there are few validated longitudinal simulation models examining the human and economic cost of obesity. This paper describes a microsimulation model as a comprehensive tool to understand the relationship between body weight, health, and economic outcomes. Patient health and economic outcomes were simulated annually over 10 years using a Markov-based microsimulation model. The obese population examined is nationally representative of obese adults in the US from the 2005-2012 National Health and Nutrition Examination Surveys, while a matched normal weight population was constructed to have similar demographics as the obese population during the same period. Prediction equations for onset of obesity-related comorbidities, medical expenditures, economic outcomes, mortality, and quality-of-life came from published trials and studies supplemented with original research. Model validation followed International Society for Pharmacoeconomics and Outcomes Research practice guidelines. Among surviving adults, relative to a matched normal weight population, obese adults averaged $3900 higher medical expenditures in the initial year, growing to $4600 higher expenditures in year 10. Obese adults had higher initial prevalence and higher simulated onset of comorbidities as they aged. Over 10 years, excess medical expenditures attributed to obesity averaged $4280 annually-ranging from $2820 for obese category I to $5100 for obese category II, and $8710 for obese category III. Each excess kilogram of weight contributed to $140 higher annual costs, on average, ranging from $136 (obese I) to $152 (obese III). Poor health associated with obesity increased work absenteeism and mortality, and lowered employment probability, personal income, and quality-of-life. This validated model helps illustrate why obese adults have higher medical and indirect costs relative to normal weight adults, and shows that medical costs for obese adults rise more rapidly with aging relative to normal weight adults.

  19. Opportunities for market-based programs worldwide that reduce greenhouse gas emissions: Initial Observations from Missions to the Philippines, South Africa, and Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanton-Hoyle, D.R.

    1998-07-01

    Globally, governments and industries are implementing innovative voluntary programs to reduce greenhouse gas emissions. Often these programs encourage groups to use cost effective technologies that capture market-based forces. These programs are successful because they capitalize on existing opportunities where both the environment and the participants can benefit (i.e., win-win opportunities). This paper documents efforts to investigate these kinds of win-win opportunities in three developing countries: the Philippines, South Africa, and Mexico. Initial observations are provided as fresh information from the field, drawing on six missions during the last nine months. Utility costs, interest rates, and overall economic health appear tomore » critically affect opportunities in each country. By contrast, details of heating, ventilating and air-conditioning (HVAC) design and local climate were often important differences between countries. These affect opportunities, for example, to achieve significant savings from cooling systems or not. Looking at the success of ESCOs was somewhat surprising. One might expect to see the most successful ESCO activity where utility costs are high and upgrade opportunities are plentiful (such as in the Philippines). This was not the case, however, as research in the Philippines did not reveal even one active ESCO contract yet. Design practices for new construction were in need of the same thing that helps US design teams do a better job of energy-efficient design, better communications between design team members. Finally, industrial firms were doing a variety of EE upgrades in each country, but this level of activity was relatively small compared to what should be cost effective.« less

  20. Time-driven activity-based costing of low-dose-rate and high-dose-rate brachytherapy for low-risk prostate cancer.

    PubMed

    Ilg, Annette M; Laviana, Aaron A; Kamrava, Mitchell; Veruttipong, Darlene; Steinberg, Michael; Park, Sang-June; Burke, Michael A; Niedzwiecki, Douglas; Kupelian, Patrick A; Saigal, Christopher

    Cost estimates through traditional hospital accounting systems are often arbitrary and ambiguous. We used time-driven activity-based costing (TDABC) to determine the true cost of low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy for prostate cancer and demonstrate opportunities for cost containment at an academic referral center. We implemented TDABC for patients treated with I-125, preplanned LDR and computed tomography based HDR brachytherapy with two implants from initial consultation through 12-month followup. We constructed detailed process maps for provision of both HDR and LDR. Personnel, space, equipment, and material costs of each step were identified and used to derive capacity cost rates, defined as price per minute. Each capacity cost rate was then multiplied by the relevant process time and products were summed to determine total cost of care. The calculated cost to deliver HDR was greater than LDR by $2,668.86 ($9,538 vs. $6,869). The first and second HDR treatment day cost $3,999.67 and $3,955.67, whereas LDR was delivered on one treatment day and cost $3,887.55. The greatest overall cost driver for both LDR and HDR was personnel at 65.6% ($4,506.82) and 67.0% ($6,387.27) of the total cost. After personnel costs, disposable materials contributed the second most for LDR ($1,920.66, 28.0%) and for HDR ($2,295.94, 24.0%). With TDABC, the true costs to deliver LDR and HDR from the health system perspective were derived. Analysis by physicians and hospital administrators regarding the cost of care afforded redesign opportunities including delivering HDR as one implant. Our work underscores the need to assess clinical outcomes to understand the true difference in value between these modalities. Copyright © 2016 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  1. Recycling of construction debris as aggregate in the Mid-Atlantic Region, USA

    USGS Publications Warehouse

    Robinson, G.R.; Menzie, W.D.; Hyun, H.

    2004-01-01

    Reclaimed asphalt pavement (RAP) and portland cement concrete (RPCC) are abundant and available substitutes for natural aggregate in many areas. This paper presents an overview of factors that affect recycled aggregate cost, availability, and engineering performance, and the results of a survey of business practices in the Mid-Atlantic region. For RAP, processing costs are less than those for virgin natural aggregate. Use of efficient asphalt pavement stripping technology, on-site reclamation, and linked two-way transport of asphalt debris and processed asphalt paving mix between asphalt mix plants and paving sites has led to extensive recycling of asphalt pavement in the Mid-Atlantic region of the US. Most of the sites that recycle asphalt pavement (RAP) are located in or near urban areas close to important transportation corridors. RPCC is a viable aggregate source in urban settings where unit costs for processed aggregate from RPCC and natural aggregate are comparable. Disposal fees charged at RPCC recycling sites help defray processing costs and the significantly lower tipping fees at recycling sites versus landfill disposal sites encourage recycling of construction debris as aggregate. Construction contractors and construction debris recycling centers, many of which have the ability to crush and process concrete debris at the job site, produce most RPCC. Production of RPCC aggregate from construction debris that is processed on site using portable equipment moved to the construction site eliminates transportation costs for aggregate and provides an economic incentive for RPCC use. Processing costs, quality and performance issues, and lack of large quantities where needed limit RPCC use. Most RPCC suppliers in the Mid-Atlantic area are located in counties with population densities greater than 400 people/km2 (1036 people/mile2) and that have high unit-value costs and limited local availability of natural aggregate. ?? 2004 Published by Elsevier B.V.

  2. Construction Management Meets Today's Realities.

    ERIC Educational Resources Information Center

    Day, C. William

    1979-01-01

    Construction management--the control of cost and time from concept through construction--grew out of a need to meet the realities of today's economy. A checklist of services a construction manager provides is presented. (Author/MLF)

  3. Army ants dynamically adjust living bridges in response to a cost–benefit trade-off

    PubMed Central

    Reid, Chris R.; Lutz, Matthew J.; Powell, Scott; Kao, Albert B.; Couzin, Iain D.; Garnier, Simon

    2015-01-01

    The ability of individual animals to create functional structures by joining together is rare and confined to the social insects. Army ants (Eciton) form collective assemblages out of their own bodies to perform a variety of functions that benefit the entire colony. Here we examine ‟bridges” of linked individuals that are constructed to span gaps in the colony’s foraging trail. How these living structures adjust themselves to varied and changing conditions remains poorly understood. Our field experiments show that the ants continuously modify their bridges, such that these structures lengthen, widen, and change position in response to traffic levels and environmental geometry. Ants initiate bridges where their path deviates from their incoming direction and move the bridges over time to create shortcuts over large gaps. The final position of the structure depended on the intensity of the traffic and the extent of path deviation and was influenced by a cost–benefit trade-off at the colony level, where the benefit of increased foraging trail efficiency was balanced by the cost of removing workers from the foraging pool to form the structure. To examine this trade-off, we quantified the geometric relationship between costs and benefits revealed by our experiments. We then constructed a model to determine the bridge location that maximized foraging rate, which qualitatively matched the observed movement of bridges. Our results highlight how animal self-assemblages can be dynamically modified in response to a group-level cost–benefit trade-off, without any individual unit’s having information on global benefits or costs. PMID:26598673

  4. Impact of the Economic Growth and Acquisition of Land to the Construction Cost Index in North Sumatra

    NASA Astrophysics Data System (ADS)

    Tarmizi, H. B.; Daulay, M.; Muda, I.

    2017-03-01

    This study aims to test the aggregation of the economic growth of North Sumatra and the influence of the Tax on Acquisition of Land and Building to the Construction Cost Index in North Sumatra. This type of research is explanatory survey with quantitative methods. The population and the sample district in North Sumatra with the observation time series and cross sectional. The analysis tool used is multiple regression. The results showed that there was economic growth aggregation of North Sumatra and the influence of the Tax on Acquisition of Land and Building affect the Construction Cost Index.

  5. Study and evaluation of ferro-cement for use in wind tunnel construction

    NASA Technical Reports Server (NTRS)

    Larsen, H. J., Jr. (Compiler)

    1972-01-01

    The structural suitability and cost effectiveness of ferro-cement for large subsonic wind tunnel structures is investigated. This investigation was carried out in the following four main categories: (1) a state-of-the-art survey into the uses, properties, and costs of ferro-cement; (2) an evaluation of those ferro-cement properties critical to construction of large, subsonic wind tunnels, which have not been adequately established to date; (3) a laboratory testing program to determine preliminary values for those properties; and (4) a study to establish cost factors for ferro-cement as related to a preliminary construction scheme for a nacelle and shroud unit.

  6. Cost-Effectiveness Analysis of Early Reconstruction Versus Rehabilitation and Delayed Reconstruction for Anterior Cruciate Ligament Tears.

    PubMed

    Mather, Richard C; Hettrich, Carolyn M; Dunn, Warren R; Cole, Brian J; Bach, Bernard R; Huston, Laura J; Reinke, Emily K; Spindler, Kurt P

    2014-07-01

    An initial anterior cruciate ligament (ACL) tear can be treated with surgical reconstruction or focused rehabilitation. The KANON (Knee Anterior cruciate ligament, NON-surgical versus surgical treatment) randomized controlled trial compared rehabilitation plus early ACL reconstruction (ACLR) to rehabilitation plus optional delayed ACLR and found no difference at 2 years by an intention-to-treat analysis of total Knee injury and Osteoarthritis Outcome Score (KOOS) results. To compare the cost-effectiveness of early versus delayed ACLR. Economic and decision analysis; Level of evidence, 2. A Markov decision model was constructed for a cost-utility analysis of early reconstruction (ER) versus rehabilitation plus optional delayed reconstruction (DR). Outcome probabilities and effectiveness were derived from 2 sources: the KANON study and the Multicenter Orthopaedic Outcomes Network (MOON) database. Collectively, these 2 sources provided data from 928 ACL-injured patients. Utilities were measured by the Short Form-6 dimensions (SF-6D). Costs were estimated from a societal perspective in 2012 US dollars. Costs and utilities were discounted in accordance with the United States Panel on Cost-Effectiveness in Health and Medicine. Effectiveness was expressed in quality-adjusted life-years (QALYs) gained. Principal outcome measures were average incremental costs, incremental effectiveness (as measured by QALYs), and net health benefits. Willingness to pay was set at $50,000, which is the currently accepted standard in the United States. In the base case, the ER group resulted in an incremental gain of 0.28 QALYs over the DR group, with a corresponding lower overall cost to society of $1572. Effectiveness gains were driven by the low utility of an unstable knee and the lower utility for the DR group. The cost of rehabilitation and the rate of additional surgery drove the increased cost of the DR group. The most sensitive variable was the rate of knee instability after initial rehabilitation. When the rate of instability falls to 51.5%, DR is less costly, and when the rate of instability falls below 18.0%, DR becomes the preferred cost-effective strategy. An economic analysis of the timing of ACLR using data exclusively from the KANON trial, MOON cohort, and national average reimbursement revealed that early ACLR was more effective (improved QALYs) at a lower cost than rehabilitation plus optional delayed ACLR. Therefore, early ACLR should be the preferred treatment strategy from a societal health system perspective. © 2014 The Author(s).

  7. Impact of ICT on Performance of Construction Companies in Slovakia

    NASA Astrophysics Data System (ADS)

    Mesároš, Peter; Mandičák, Tomáš

    2017-10-01

    Information and communication technologies became a part of management tools in modern companies. Construction industry and its participants deal with a serious requirement for processing the huge amount of information on construction projects including design, construction, time and cost parameters, economic efficiency and sustainability. To fulfil this requirement, companies have to use appropriate ICT tools. Aim of the paper is to examine the impact of ICT exploitation on performance of construction companies. The impact of BIM tools, ERP systems and controlling system on cost and profit indicators will be measured on the sample of 85 companies from construction industry in Slovakia. Enterprise size, enterprise ownership and role in construction process will be set as independent variables for statistical analyse. The results will be considered for different groups of companies.

  8. Cost effectiveness of tobacco control policies in Vietnam: the case of population-level interventions.

    PubMed

    Higashi, Hideki; Truong, Khoa D; Barendregt, Jan J; Nguyen, Phuong K; Vuong, Mai L; Nguyen, Thuy T; Hoang, Phuong T; Wallace, Angela L; Tran, Tien V; Le, Cuong Q; Doran, Christopher M

    2011-05-01

    Tobacco smoking is one of the leading public health problems in the world. It is also possible to prevent and/or reduce the harm from tobacco use through the use of cost-effective tobacco control measures. However, most of this evidence comes from developed countries and little research has been conducted on this issue in developing countries. The objective of this study was to analyse the cost effectiveness of four population-level tobacco control interventions in Vietnam. Four tobacco control interventions were evaluated: excise tax increase; graphic warning labels on cigarette packs; mass media campaigns; and smoking bans (in public or in work places). A multi-state life table model was constructed in Microsoft® Excel to examine the cost effectiveness of the tobacco control intervention options. A government perspective was adopted, with costing conducted using a bottom-up approach. Health improvement was considered in terms of disability-adjusted life-years (DALYs) averted. All assumptions were subject to sensitivity and uncertainty analysis. All the interventions fell within the definition of being very cost effective according to the threshold level suggested by the WHO (i.e.

  9. Cost-effectiveness of prenatal screening strategies for congenital heart disease.

    PubMed

    Pinto, N M; Nelson, R; Puchalski, M; Metz, T D; Smith, K J

    2014-07-01

    The economic implications of strategies to improve prenatal screening for congenital heart disease (CHD) in low-risk mothers have not been explored. The aim was to perform a cost-effectiveness analysis of different screening methods. We constructed a decision analytic model of CHD prenatal screening strategies (four-chamber screen (4C), 4C + outflow, nuchal translucency (NT) or fetal echocardiography) populated with probabilities from the literature. The model included whether initial screens were interpreted by a maternal-fetal medicine (MFM) specialist and different referral strategies if they were read by a non-MFM specialist. The primary outcome was the incremental cost per defect detected. Costs were obtained from Medicare National Fee estimates. A probabilistic sensitivity analysis was undertaken on model variables commensurate with their degree of uncertainty. In base-case analysis, 4C + outflow referred to an MFM specialist was the least costly strategy per defect detected. The 4C screen and the NT screen were dominated by other strategies (i.e. were more costly and less effective). Fetal echocardiography was the most effective, but most costly. On simulation of 10 000 low-risk pregnancies, 4C + outflow screen referred to an MFM specialist remained the least costly per defect detected. For an additional $580 per defect detected, referral to cardiology after a 4C + outflow was the most cost-effective for the majority of iterations, increasing CHD detection by 13 percentage points. The addition of examination of the outflow tracts to second-trimester ultrasound increases detection of CHD in the most cost-effective manner. Strategies to improve outflow-tract imaging and to refer with the most efficiency may be the best way to improve detection at a population level. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd.

  10. Economic and medical benefits of ultrasound screenings for gallstone disease.

    PubMed

    Shen, Hung-Ju; Hsu, Chung-Te; Tung, Tao-Hsin

    2015-03-21

    To investigate whether screening for gallstone disease was economically feasible and clinically effective. This clinical study was initially conducted in 2002 in Taipei, Taiwan. The study cohort total included 2386 healthy adults who were voluntarily admitted to a regional teaching hospital for a physical check-up. Annual follow-up screening with ultrasound sonography for gallstone disease continued until December 31, 2007. A decision analysis using the Markov Decision Model was constructed to compare different screening regimes for gallstone disease. The economic evaluation included estimates of both the cost-effectiveness and cost-utility of screening for gallstone disease. Direct costs included the cost of screening, regular clinical fees, laparoscopic cholecystectomy, and hospitalization. Indirect costs represent the loss of productivity attributable to the patient's disease state, and were estimated using the gross domestic product for 2011 in Taiwan. Longer time intervals in screening for gallstone disease were associated with the reduced efficacy and utility of screening and with increased cost. The cost per life-year gained (average cost-effectiveness ratio) for annual screening, biennial screening, 3-year screening, 4-year screening, 5-year screening, and no-screening was new Taiwan dollars (NTD) 39076, NTD 58059, NTD 72168, NTD 104488, NTD 126941, and NTD 197473, respectively (P < 0.05). The cost per quality-adjusted life-year gained by annual screening was NTD 40725; biennial screening, NTD 64868; 3-year screening, NTD 84532; 4-year screening, NTD 110962; 5-year screening, NTD 142053; and for the control group, NTD 202979 (P < 0.05). The threshold values indicated that the ultrasound sonography screening programs were highly sensitive to screening costs in a plausible range. Routine screening regime for gallstone disease is both medically and economically valuable. Annual screening for gallstone disease should be recommended.

  11. 13 CFR 120.884 - Ineligible costs for 504 loans.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Construction equipment (except for heavy duty construction equipment integral to a business' operations and... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Ineligible costs for 504 loans. 120.884 Section 120.884 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS...

  12. On the Path to SunShot: Advancing Concentrating Solar Power Technology Performance and Dispatchability.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mehos, Mark; Turchi, Craig; Jorgensen, Jennie

    2016-03-01

    Since the SunShot Vision Study (DOE 2012) was published, global deployment of concentrating solar power (CSP) has increased threefold to nearly 4,500 MW, with a similar threefold increase in operational capacity to 1,650 MW within the United States. Growth in U.S. CSP capacity has primarily been driven by policy support at the state and federal levels. State-driven renewable portfolio standards (RPSs), combined with a 30% federal investment tax credit (ITC) and federal loan guarantees, provided the opportunity for CSP developers to kick-start construction of CSP plants throughout the Southwest. Figure ES-1 demonstrates that deployment and private- and public-sector research andmore » development have led to dramatic cost reductions that have placed CSP well on the path to reaching the U.S. Department of Energy’s SunShot Initiative goal of 6 cents/kWh by 2020. In comparing the estimated capital costs from the SunShot Vision Study and the current analysis, we find that parabolic trough solar-field costs have fallen more rapidly than predicted, although the drop in solar-field costs was offset by the additional costs of moving from a wet-cooled power block in 2010 to a more expensive dry-cooled power block in 2015. The predicted 2015 decline in tower costs was in line with expectations, primarily driven by reduced heliostat costs. Figure ES-1 shows the reduction in levelized cost of electricity (LCOE) for both parabolic trough and tower systems, in addition to the projected 2020 SunShot target.« less

  13. Comparative Study on the Cost of Building Public House Construction Using Red Brick and Interlock Brick Building Material in the City of Banda Aceh

    NASA Astrophysics Data System (ADS)

    Malahayati, Nurul; Hayati, Yulia; Nursaniah, Cut; Firsa, T.; Fachrurrazi; Munandar, Aris

    2018-05-01

    Red brick and interlocking brick are the building materials that are often used for wall installation work on houses construction. In the development of building materials technology and cost savings, interlocking brick can be alternative to replace red bricks. In Aceh Province, the use of interlocking bricks is less popular compared to other big cities in Indonesia. Interlocking brick is made from a mixture of clay, concrete sand and compacted cement and one of the environmentally friendly materials because it does not burn the process like red brick material. It is named interlocking brick because the installation method is locked together and it serves as a structural and partition wall of residential buildings. The aims of this study are to compare the cost of building a house in Banda Aceh City using red brick and interlock brick building materials. The data were obtained from interviews and questionnaires distributed to respondents who had built houses in Banda Aceh City. The results concluded that the house construction cost using interlock brick offer lower construction cost at comparable quality rather than using red brick.

  14. "Red-Yellow-Green": Effect of an Initiative to Guide Surgeon Choice of Orthopaedic Implants.

    PubMed

    Okike, Kanu; Pollak, Rachael; O'Toole, Robert V; Pollak, Andrew N

    2017-04-05

    Orthopaedic procedures are expensive, and devices account for a large proportion of the overall costs. Hospitals have employed a variety of strategies to decrease implant costs, but many center on restricting surgeon choice. At our institution, we developed an implant selection tool that guides surgeons toward more cost-effective implants, while minimally restricting choice. The purpose of this study was to assess the effect of this tool on preferred implant usage rates, vendor attitudes toward pricing structure, and hospital implant expenditures. For 6 commonly used orthopaedic trauma devices, similar constructs were created for the 4 vendors used at our hospital, and the costs were determined. On the basis of these costs, the available options for each device type were categorized as "green" (preferred vendor), "yellow" (midrange), or "red" (used for patient-specific requirements). The "Red-Yellow-Green" chart was posted on the wall of each orthopaedic trauma operating room. To assess the effect of the tool, we compared implant usage patterns before and after implementation of the implant selection tool. We also assessed changes in vendor contract prices, as well as overall savings to our institution. Implant usage changed significantly from 30% "red," 56% "yellow," and 14% "green" prior to the intervention, to 9% "red," 21% "yellow," and 70% "green" after the intervention (p < 0.0001). As a result of price renegotiation with vendors following implementation, we observed average price decreases that ranged from 1.1% to 22.4%. Average expenditures on these 6 implants decreased 20% during the study period, which represented a savings of $216,495 per year. At our institution, we designed and implemented "Red-Yellow-Green," a simple tool that guides surgeons toward the selection of lower-cost implants without violating vendor confidentiality clauses, limiting the implants from which surgeons can choose, or requiring surgeons to discern the prices of complex constructs. Following implementation, hospital implant expenditures decreased as a result of a combination of increased preferred vendor usage by surgeons, as well as increased competition among vendors, which resulted in lower overall prices.

  15. 14 CFR 151.55 - Accounting and audit.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Costs of force account construction. (5) Engineering costs of plans and designs. (6) Engineering costs... allowability of all incurred costs of the project. The sponsor shall segregate and group project costs so that it can furnish, on due notice, cost information in the following cost classifications: (1) Purchase...

  16. 14 CFR 151.55 - Accounting and audit.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Costs of force account construction. (5) Engineering costs of plans and designs. (6) Engineering costs... allowability of all incurred costs of the project. The sponsor shall segregate and group project costs so that it can furnish, on due notice, cost information in the following cost classifications: (1) Purchase...

  17. 14 CFR 151.55 - Accounting and audit.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Costs of force account construction. (5) Engineering costs of plans and designs. (6) Engineering costs... allowability of all incurred costs of the project. The sponsor shall segregate and group project costs so that it can furnish, on due notice, cost information in the following cost classifications: (1) Purchase...

  18. 14 CFR 151.55 - Accounting and audit.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Costs of force account construction. (5) Engineering costs of plans and designs. (6) Engineering costs... allowability of all incurred costs of the project. The sponsor shall segregate and group project costs so that it can furnish, on due notice, cost information in the following cost classifications: (1) Purchase...

  19. Ford-Class Aircraft Carrier: Congress Should Consider Revising Cost Cap Legislation to Include All Construction Costs

    DTIC Science & Technology

    2014-11-01

    thus increasing the likelihood of additional testing delays. For example, testing of the ship’s fire sprinklers was delayed because construction of...not deploy as scheduled or will deploy without fully tested systems . The Navy is implementing steps to achieve the $11.5 billion congressional cost...cap, by postponing installation of some systems until after ship delivery, and deferring an estimated $200 million - $250 million in previously

  20. 75 FR 1403 - Notice of Proposed Information Collection for 1004-0102

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... to pay private landowners for the use and/or maintenance of their roads. These fees represent the BLM's share of road construction and maintenance costs under reciprocal right-of-way agreements between... contract, and to amortize road construction and maintenance costs among several road users. Frequency of...

  1. 47 CFR 54.636 - Eligible participant-constructed and owned network facilities for consortium applicants.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Support for Health Care Providers Healthcare Connect Fund § 54.636 Eligible participant-constructed and... proposals. Requests for proposals must provide sufficient detail so that cost-effectiveness can be evaluated... its own network facilities is the most cost-effective option after competitive bidding, pursuant to...

  2. 47 CFR 54.636 - Eligible participant-constructed and owned network facilities for consortium applicants.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Support for Health Care Providers Healthcare Connect Fund § 54.636 Eligible participant-constructed and... proposals. Requests for proposals must provide sufficient detail so that cost-effectiveness can be evaluated... its own network facilities is the most cost-effective option after competitive bidding, pursuant to...

  3. 18 CFR 4.10 - Valuation data.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PROJECT COSTS Determination of Fair Value of Constructed Projects, Under Section 23(a) of the Act § 4.10... Power Act that requires the determination of the fair value of a project already constructed, the... a statement to the effect that the actual legitimate original cost, or if not known, the estimated...

  4. 18 CFR 4.10 - Valuation data.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PROJECT COSTS Determination of Fair Value of Constructed Projects, Under Section 23(a) of the Act § 4.10... Power Act that requires the determination of the fair value of a project already constructed, the... a statement to the effect that the actual legitimate original cost, or if not known, the estimated...

  5. 18 CFR 4.10 - Valuation data.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PROJECT COSTS Determination of Fair Value of Constructed Projects, Under Section 23(a) of the Act § 4.10... Power Act that requires the determination of the fair value of a project already constructed, the... a statement to the effect that the actual legitimate original cost, or if not known, the estimated...

  6. [Discovery of potential LXRβ agonists from Chinese herbs using molecular simulation methods].

    PubMed

    Luo, Gang-Gang; Lu, Fang; Qiao, Lian-Sheng; Li, Yong; Zhang, Yan-Ling

    2016-08-01

    Liver X receptor β (LXRβ) has been a new target in the treatment of hyperlipemia, which was related to the cholesterol homeostasis. In this study, the quantitative pharmacophores were constructed by 3D-QSAR pharmacophore (Hypogen) method based on the LXRβ agonists. The optimal pharmacophore model containing one hydrogen bond acceptor, two hydrophobics and one ring aromatic was obtained based on five assessment indictors, including the correlation between predicted value and experimental value of the compounds in training set (correlation), Δcost of the models (Δcost), hit rate of active compounds (HRA), identification of effectiveness index (IEI) and comprehensive evaluation index (CAI). And the values of the five assessment indicators were 0.95, 128.65, 84.44%, 2.58 and 2.18 respectively. The best model as a query to screen the traditional Chinese medicine database (TCMD), a list of 309 compounds was obtained andwere then refined using Libdock program. Finally, based on the screening rules of the Libdock score of initial compound and the key interactions between initial compound and receptor, four compounds, demethoxycurcumin, isolicoflavonol, licochalcone E and silydianin, were selected as potential LXRβ agonists. The molecular simulation methods were high-efficiency and time-saving to obtainthe potential LXRβ agonists, which could provide assistance for further researchingnovel anti-hyperlipidemia drugs. Copyright© by the Chinese Pharmaceutical Association.

  7. Direct medical costs and medication compliance among fibromyalgia patients: duloxetine initiators vs. pregabalin initiators.

    PubMed

    Sun, Peter; Peng, Xiaomei; Sun, Steve; Novick, Diego; Faries, Douglas E; Andrews, Jeffrey S; Wohlreich, Madelaine M; Wu, Andrew

    2014-01-01

    To assess and compare direct medical costs and medication compliance between patients with fibromyalgia who initiated duloxetine and patients with fibromyalgia who initiated pregabalin in 2008. A retrospective cohort study design was used based on a large US national commercial claims database (2006 to 2009). Patients with fibromyalgia aged 18 to 64 who initiated duloxetine or pregabalin in 2008 and who had continuous health insurance 1 year preceding and 1 year following the initiation were selected into duloxetine cohort or pregabalin cohort based on their initiated agent. Medication compliance was measured by total supply days, medication possession ratio (MPR), and proportion of patients with MPR ≥ 0.8. Direct medical costs were measured by annual costs per patient and compared between the cohorts in the year following the initiation. Propensity score stratification and bootstrapping methods were used to adjust for distribution bias, as well as cross-cohort differences in demographic, clinical and economic characteristics, and medication history prior to the initiation. Both the duloxetine (n = 3,033) and pregabalin (n = 4,838) cohorts had a mean initiation age around 49 years, 89% were women. During the postindex year, compared to the pregabalin cohort, the duloxetine cohort had higher totally annual supply days (273.5 vs. 176.6, P < 0.05), higher MPR (0.7 vs. 0.5, P < 0.05), and more patients with MPR ≥ 0.8 (45.1% vs. 29.4%, P < 0.05). Further, relative to pregabalin cohort, duloxetine cohort had lower inpatient costs ($2,994.9 vs. $4,949.6, P < 0.05), lower outpatient costs ($8,259.6 vs. $10,312.2, P < 0.05), similar medication costs ($5,214.6 vs. $5,290.8, P > 0.05), and lower total medical costs ($16,469.1 vs. $20,552.6, P < 0.05) in the postinitiation year. In a real-world setting, patients with fibromyalgia who initiated duloxetine in 2008 had better medication compliance and consumed less inpatient, outpatient, and total medical costs than those who initiated pregabalin. © 2013 The Authors Pain Practice © 2013 World Institute of Pain.

  8. Cost Analysis of a High Support Housing Initiative for Persons with Severe Mental Illness and Long-Term Psychiatric Hospitalization.

    PubMed

    Rudoler, David; de Oliveira, Claire; Jacob, Binu; Hopkins, Melonie; Kurdyak, Paul

    2018-01-01

    The objective of this article was to conduct a cost analysis comparing the costs of a supportive housing intervention to inpatient care for clients with severe mental illness who were designated alternative-level care while inpatient at the Centre for Addiction and Mental Health in Toronto. The intervention, called the High Support Housing Initiative, was implemented in 2013 through a collaboration between 15 agencies in the Toronto area. The perspective of this cost analysis was that of the Ontario Ministry of Health and Long-Term Care. We compared the cost of inpatient mental health care to high-support housing. Cost data were derived from a variety of sources, including health administrative data, expenditures reported by housing providers, and document analysis. The High Support Housing Initiative was cost saving relative to inpatient care. The average cost savings per diem were between $140 and $160. This amounts to an annual cost savings of approximately $51,000 to $58,000. When tested through sensitivity analysis, the intervention remained cost saving in most scenarios; however, the result was highly sensitive to health system costs for clients of the High Support Housing Initiative program. This study suggests the High Support Housing Initiative is potentially cost saving relative to inpatient hospitalization at the Centre for Addiction and Mental Health.

  9. Title I preliminary engineering for: A. S. E. F. solid waste to methane gas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1976-01-01

    An assignment to provide preliminary engineering of an Advanced System Experimental Facility for production of methane gas from urban solid waste by anaerobic digestion is documented. The experimental facility will be constructed on a now-existing solid waste shredding and landfill facility in Pompano Beach, Florida. Information is included on: general description of the project; justification of basic need; process design; preliminary drawings; outline specifications; preliminary estimate of cost; and time schedules for design and construction of accomplishment of design and construction. The preliminary cost estimate for the design and construction phases of the experimental program is $2,960,000, based on Dec.more » 1975 and Jan. 1976 costs. A time schedule of eight months to complete the Detailed Design, Equipment Procurement and the Award of Subcontracts is given.« less

  10. Cost Sharing, Family Health Care Burden, and the Use of Specialty Drugs for Rheumatoid Arthritis

    PubMed Central

    Karaca-Mandic, Pinar; Joyce, Geoffrey F; Goldman, Dana P; Laouri, Marianne

    2010-01-01

    Objectives To examine the impact of benefit generosity and household health care financial burden on the demand for specialty drugs in the treatment of rheumatoid arthritis (RA). Data Sources/Study Setting Enrollment, claims, and benefit design information for 35 large private employers during 2000–2005. Study Design We estimated multivariate models of the effects of benefit generosity and household financial burden on initiation and continuation of biologic therapies. Data Extraction Methods We defined initiation of biologic therapy as first-time use of etanercept, adalimumab, or infliximab, and we constructed an index of plan generosity based on coverage of biologic therapies in each plan. We estimated the household's burden by summing up the annual out-of-pocket (OOP) expenses of other family members. Principal Findings Benefit generosity affected both the likelihood of initiating a biologic and continuing drug therapy, although the effects were stronger for initiation. Initiation of a biologic was lower in households where other family members incurred high OOP expenses. Conclusions The use of biologic therapy for RA is sensitive to benefit generosity and household financial burden. The increasing use of coinsurance rates for specialty drugs (as under Medicare Part D) raises concern about adverse health consequences. PMID:20831715

  11. A cost-effective approach to establishing a surgical skills laboratory.

    PubMed

    Berg, David A; Milner, Richard E; Fisher, Carol A; Goldberg, Amy J; Dempsey, Daniel T; Grewal, Harsh

    2007-11-01

    Recent studies comparing inexpensive low-fidelity box trainers to expensive computer-based virtual reality systems demonstrate similar acquisition of surgical skills and transferability to the clinical setting. With new mandates emerging that all surgical residency programs have access to a surgical skills laboratory, we describe our cost-effective approach to teaching basic and advanced open and laparoscopic skills utilizing inexpensive bench models, box trainers, and animate models. Open models (basic skills, bowel anastomosis, vascular anastomosis, trauma skills) and laparoscopic models (basic skills, cholecystectomy, Nissen fundoplication, suturing and knot tying, advanced in vivo skills) are constructed using a combination of materials found in our surgical research laboratories, retail stores, or donated by industry. Expired surgical materials are obtained from our hospital operating room and animal organs from food-processing plants. In vivo models are performed in an approved research facility. Operation, maintenance, and administration of the surgical skills laboratory are coordinated by a salaried manager, and instruction is the responsibility of all surgical faculty from our institution. Overall, the cost analyses of our initial startup costs and operational expenditures over a 3-year period revealed a progressive decrease in yearly cost per resident (2002-2003, $1,151; 2003-2004, $1,049; and 2004-2005, $982). Our approach to surgical skills education can serve as a template for any surgery program with limited financial resources.

  12. Use and cost comparison of clobazam to other antiepileptic drugs for treatment of Lennox-Gastaut syndrome

    PubMed Central

    François, Clément; Stern, John M.; Ogbonnaya, Augustina; Lokhandwala, Tasneem; Landsman-Blumberg, Pamela; Duhig, Amy; Shen, Vivienne; Tan, Robin

    2017-01-01

    ABSTRACT Background: Lennox-Gastaut syndrome (LGS) is a severe form of childhood-onset epilepsy associated with serious injuries due to frequent and severe seizures. Of the antiepileptic drugs (AEDs) approved for LGS, clobazam is a more recent market entrant, having been approved in October 2011. Recent AED budget impact and cost-effectiveness analyses for LGS suggest that adding clobazam to a health plan formulary may result in decreased medical costs; however, research on clinical and economic outcomes and treatment patterns with these AED treatments in LGS is limited. Objectives: To compare the baseline characteristics and treatment patterns of new initiators of clobazam and other AEDs among LGS patients and compare healthcare utilization and costs before and after clobazam initiation among LGS patients. Methods: A retrospective study of probable LGS patients was conducted using the MarketScan® Commercial, Medicare Supplemental, and Medicaid databases (10/1/2010-3/31/2014). Results: In the Commercial/Medicare Supplemental population, clobazam users were younger, had fewer comorbidities, and more prior AED use than non-clobazam users. In the 12 months pre-treatment initiation, clobazam users had significantly more seizure-related inpatient stays and outpatient visits and higher total seizure-related (P < 0.001) and all-cause (P < 0.001) costs than non-clobazam users. Among clobazam users, when compared to the 12 months pre-clobazam initiation, seizure-related medical utilization and costs were lower in the 12 months post-clobazam initiation (P = 0.004). Total all-cause (P < 0.001) and seizure-related (P = 0.029) costs increased post-clobazam initiation mainly due to the increase in outpatient pharmacy costs. Similar results were observed in the Medicaid population. Conclusions: Baseline results suggest a prescribing preference for clobazam in severe LGS patients. Clobazam users had a reduction in seizure-related medical utilization and costs after clobazam initiation. The improvement in medical costs mostly offset the higher prescription costs following clobazam initiation. PMID:28740620

  13. Data Flow in Relation to Life-Cycle Costing of Construction Projects in the Czech Republic

    NASA Astrophysics Data System (ADS)

    Biolek, Vojtěch; Hanák, Tomáš; Marović, Ivan

    2017-10-01

    Life-cycle costing is an important part of every construction project, as it makes it possible to take into consideration future costs relating to the operation and demolition phase of a built structure. In this way, investors can optimize the project design to minimize the total project costs. Even though there have already been some attempts to implement BIM software in the Czech Republic, the current state of affairs does not support automated data flow between the bill of costs and applications that support building facility management. The main aim of this study is to critically evaluate the current situation and outline a future framework that should allow for the use of the data contained in the bill of costs to manage building operating costs.

  14. 28 CFR 91.22 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...), pre-architectural programming, architectural design, preservation, construction, administration, construction management, or project management costs. Construction does not include the purchase of land. [61... U.S.C. 450b(e). (e) Construction means the erection, acquisition, renovation, repair, remodeling, or...

  15. 28 CFR 91.22 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...), pre-architectural programming, architectural design, preservation, construction, administration, construction management, or project management costs. Construction does not include the purchase of land. [61... U.S.C. 450b(e). (e) Construction means the erection, acquisition, renovation, repair, remodeling, or...

  16. 28 CFR 91.22 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...), pre-architectural programming, architectural design, preservation, construction, administration, construction management, or project management costs. Construction does not include the purchase of land. [61... U.S.C. 450b(e). (e) Construction means the erection, acquisition, renovation, repair, remodeling, or...

  17. 28 CFR 91.22 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...), pre-architectural programming, architectural design, preservation, construction, administration, construction management, or project management costs. Construction does not include the purchase of land. [61... U.S.C. 450b(e). (e) Construction means the erection, acquisition, renovation, repair, remodeling, or...

  18. Space Construction System Analysis. Part 2: Executive summary

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A detailed, end-to-end analysis of the activities, techniques, equipment and Shuttle provisions required to construct a reference project system is described. Included are: platform definition; construction analysis; cost and programmatics; and space construction experiments concepts.

  19. 28 CFR 91.22 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...), pre-architectural programming, architectural design, preservation, construction, administration, construction management, or project management costs. Construction does not include the purchase of land. [61... U.S.C. 450b(e). (e) Construction means the erection, acquisition, renovation, repair, remodeling, or...

  20. Construction Management: Building Schools Faster in the International Marketplace

    ERIC Educational Resources Information Center

    Scarano, Joseph J.

    1976-01-01

    Construction management accelerates school construction, increases quality and labor productivity, lowers costs, and offers developing nations an opportunity to improve their own management capabilities. (MLF)

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