Caching Joint Shortcut Routing to Improve Quality of Service for Information-Centric Networking.

PubMed

Huang, Baixiang; Liu, Anfeng; Zhang, Chengyuan; Xiong, Naixue; Zeng, Zhiwen; Cai, Zhiping

2018-05-29

Hundreds of thousands of ubiquitous sensing (US) devices have provided an enormous number of data for Information-Centric Networking (ICN), which is an emerging network architecture that has the potential to solve a great variety of issues faced by the traditional network. A Caching Joint Shortcut Routing (CJSR) scheme is proposed in this paper to improve the Quality of service (QoS) for ICN. The CJSR scheme mainly has two innovations which are different from other in-network caching schemes: (1) Two routing shortcuts are set up to reduce the length of routing paths. Because of some inconvenient transmission processes, the routing paths of previous schemes are prolonged, and users can only request data from Data Centers (DCs) until the data have been uploaded from Data Producers (DPs) to DCs. Hence, the first kind of shortcut is built from DPs to users directly. This shortcut could release the burden of whole network and reduce delay. Moreover, in the second shortcut routing method, a Content Router (CR) which could yield shorter length of uploading routing path from DPs to DCs is chosen, and then data packets are uploaded through this chosen CR. In this method, the uploading path shares some segments with the pre-caching path, thus the overall length of routing paths is reduced. (2) The second innovation of the CJSR scheme is that a cooperative pre-caching mechanism is proposed so that QoS could have a further increase. Besides being used in downloading routing, the pre-caching mechanism can also be used when data packets are uploaded towards DCs. Combining uploading and downloading pre-caching, the cooperative pre-caching mechanism exhibits high performance in different situations. Furthermore, to address the scarcity of storage size, an algorithm that could make use of storage from idle CRs is proposed. After comparing the proposed scheme with five existing schemes via simulations, experiments results reveal that the CJSR scheme could reduce the total number of processed interest packets by 54.8%, enhance the cache hits of each CR and reduce the number of total hop counts by 51.6% and cut down the length of routing path for users to obtain their interested data by 28.6⁻85.7% compared with the traditional NDN scheme. Moreover, the length of uploading routing path could be decreased by 8.3⁻33.3%.

Vision-aided Monitoring and Control of Thermal Spray, Spray Forming, and Welding Processes

NASA Technical Reports Server (NTRS)

Agapakis, John E.; Bolstad, Jon

1993-01-01

Vision is one of the most powerful forms of non-contact sensing for monitoring and control of manufacturing processes. However, processes involving an arc plasma or flame such as welding or thermal spraying pose particularly challenging problems to conventional vision sensing and processing techniques. The arc or plasma is not typically limited to a single spectral region and thus cannot be easily filtered out optically. This paper presents an innovative vision sensing system that uses intense stroboscopic illumination to overpower the arc light and produce a video image that is free of arc light or glare and dedicated image processing and analysis schemes that can enhance the video images or extract features of interest and produce quantitative process measures which can be used for process monitoring and control. Results of two SBIR programs sponsored by NASA and DOE and focusing on the application of this innovative vision sensing and processing technology to thermal spraying and welding process monitoring and control are discussed.

Market Innovation, Rational Housing Supply and Urban Quality at the Neighbourhood Scale

NASA Astrophysics Data System (ADS)

Puglisi, Valentina; Celani, Alberto

2017-10-01

Innovation of product, process and markets are the three categories to assess the improvement of a sector. This document is aimed to provide a review of papers about innovation in housing market and analyses solutions adopted by the international market in terms of definition of attributes of housing products. Enlightening aspects linked to quality attributes of housing products and it has been tried to read a common scheme in any study analysed to provide solutions to set innovation hints to enhance market innovation in the sector. The idea of choice, user and buyer categories definition, assessment and rating system is the backbone of the paper, as the parallelism between marketing of industrial goods and services and built environment objects. Quality of the neighbourhood and the idea of an ex-post assessment is the theme behind the last case presented, based on a research made by ABC Department of Politecnico di Milano in a neighbourhood in Milano, aimed to assess its quality.

Determinants for Failure and Success of Innovation Projects: The Road to Sustainable Educational Innovation

ERIC Educational Resources Information Center

Kirschner, P. A.; Hendricks, M.; Paas, F.; Wopereis, I.; Cordewener, B.

2004-01-01

Robert Burns wrote: "The best laid schemes of Mice and Men oft go awry". This could be considered the motto of most educational innovation. The question that arises is not so much why some innovations fail (although this is very important question), but rather why other innovations succeed? This study investigated the success factors of…

[Risk-sharing schemes: a new paradigm in adopting innovative pharmaceuticals].

PubMed

Hammerman, Ariel; Greenberg, Dan

2012-06-01

In recent years, spending on prescription drugs contributes substantially to the continuous growth in health expenditure in most Western countries. This increase in spending is influenced by both a rise in the use of existing drugs and by the adoption of new and expensive drugs. Risk-sharing agreements between pharmaceutical companies and health insurers have emerged as insurers began to deny reimbursement of expensive innovative treatments with unfavorable cost-effectiveness ratios. This occurred in cases where the expected budgetary impact was too high or when the long-term effectiveness was questionable. Risk sharing agreements serve the interests of both the insurers and the drug manufacturers. Pharmaceutical companies' interests are to dispel the uncertainties encountered by the health insurers white deciding on drug reimbursement. The insurers are interested in these agreements in order to reduce the budgetary risk while allowing their patients access to innovative drugs. Currently, only a few risk sharing agreements have been implemented, and the scientific literature on such schemes is still sparse. Since the health insurers' interest is to develop mechanisms that will contain health costs, without affecting the insured, it appears that this trend will continue to emerge. It is also likely that the adoption of similar mechanisms in the Israeli National List of Health Services updating process, would improve the accuracy of early estimates of the budgetary impact, and the actual use of the new technologies would be close to early estimates. This article reviews the principles of risk-sharing schemes and issues involved in the actual implementation of such agreements.

New trends and challenges in the European regulation of innovative medicines.

PubMed

Enzmann, Harald

2016-10-01

Regulators' marketing authorizations for innovative medicines are linked into a complex process with successive crucial decisions. Objectives and decision criteria of the stakeholders in this process, e.g. health technology assessment (HTA) bodies, payers, physicians and patients, vary and may result not only in different but even mutually exclusive requirements. Reacting to changes in scientific, economic and social demands, European regulatory agencies alter content and format of their assessment procedures and their communication. New diagnostic options (e.g. genotyping and biomarkers) and pharmaceutical innovations (e.g. targeted medicines, nanomedicines) are the scientific drivers of this development. Social drivers are the price and reimbursement decisions by HTA bodies and payers, prerequisites for most patients' access to innovative medicines. The European Medicines Agency's adaptive licensing concept and priority medicines scheme foster the early authorization of innovative medicines. HTA builds on regulators' assessment, with additional requirements and economic components. An intensified exchange between all stakeholders, e.g. in multilateral scientific advice procedures has been initiated. Diminishing the differences in the requirements of regulators and HTA bodies is in the best interest of both patients and the pharmaceutical industry, avoiding duplication of work and accelerating patients' access by early decisions on price and reimbursement. Copyright © 2016 Elsevier Inc. All rights reserved.

Energetic approach of biomass hydrolysis in supercritical water.

PubMed

Cantero, Danilo A; Vaquerizo, Luis; Mato, Fidel; Bermejo, M Dolores; Cocero, M José

2015-03-01

Cellulose hydrolysis can be performed in supercritical water with a high selectivity of soluble sugars. The process produces high-pressure steam that can be integrated, from an energy point of view, with the whole biomass treating process. This work investigates the integration of biomass hydrolysis reactors with commercial combined heat and power (CHP) schemes, with special attention to reactor outlet streams. The innovation developed in this work allows adequate energy integration possibilities for heating and compression by using high temperature of the flue gases and direct shaft work from the turbine. The integration of biomass hydrolysis with a CHP process allows the selective conversion of biomass into sugars with low heat requirements. Integrating these two processes, the CHP scheme yield is enhanced around 10% by injecting water in the gas turbine. Furthermore, the hydrolysis reactor can be held at 400°C and 23 MPa using only the gas turbine outlet streams. Copyright © 2014 Elsevier Ltd. All rights reserved.

Participatory approach: from problem identification to setting strategies for increased productivity and sustainability in small scale irrigated agriculture

NASA Astrophysics Data System (ADS)

Habtu, Solomon; Ludi, Eva; Jamin, Jean Yves; Oates, Naomi; Fissahaye Yohannes, Degol

2014-05-01

Practicing various innovations pertinent to irrigated farming at local field scale is instrumental to increase productivity and yield for small holder farmers in Africa. However the translation of innovations from local scale to the scale of a jointly operated irrigation scheme is far from trivial. It requires insight on the drivers for adoption of local innovations within the wider farmer communities. Participatory methods are expected to improve not only the acceptance of locally developed innovations within the wider farmer communities, but to allow also an estimation to which extend changes will occur within the entire irrigation scheme. On such a base, more realistic scenarios of future water productivity within an irrigation scheme, which is operated by small holder farmers, can be estimated. Initial participatory problem and innovation appraisal was conducted in Gumselassa small scale irrigation scheme, Ethiopia, from Feb 27 to March 3, 2012 as part of the EAU4FOOD project funded by EC. The objective was to identify and appraise problems which hinder sustainable water management to enhance production and productivity and to identify future research strategies. Workshops were conducted both at local (Community of Practices) and regional (Learning Practice Alliance) level. At local levels, intensive collaboration with farmers using participatory methods produced problem trees and a "Photo Safari" documented a range of problems that negatively impact on productive irrigated farming. A range of participatory methods were also used to identify local innovations. At regional level a Learning Platform was established that includes a wide range of stakeholders (technical experts from various government ministries, policy makers, farmers, extension agents, researchers). This stakeholder group did a range of exercise as well to identify major problems related to irrigated smallholder farming and already identified innovations. Both groups identified similar problems to productive smallholder irrigation: soil nutrient depletion, salinization, disease and pest resulting from inefficient irrigation practices, infrastructure problems leading to a reduction of the size of the command area and decrease in reservoir volume. The major causes have been poor irrigation infrastructure, poor on-farm soil and water management, prevalence of various crop pests and diseases, lack of inputs and reservoir siltation. On-farm participatory research focusing on soil, crop and water management issues, including technical, institutional and managerial aspects, to identify best performing innovations while taking care of the environment was recommended. Currently, a range of interlinked activities are implemented a multiple scales, combining participatory and scientific approaches towards innovation development and up-scaling of promising technologies and institutional and managerial approaches from local to regional scales. ____________________________ Key words: Irrigation scheme, productivity, innovation, participatory method, Gumselassa, Ethiopia

Viscoelastic property identification from waveform reconstruction

NASA Astrophysics Data System (ADS)

Leymarie, N.; Aristégui, C.; Audoin, B.; Baste, S.

2002-05-01

An inverse method is proposed for the determination of the viscoelastic properties of material plates from the plane-wave transmitted acoustic field. Innovations lie in a two-step inversion scheme based on the well-known maximum-likelihood principle with an analytic signal formulation. In addition, establishing the analytical formulations of the plate transmission coefficient we implement an efficient and slightly noise-sensitive process suited to both very thin plates and strongly dispersive media.

Constraining Stochastic Parametrisation Schemes Using High-Resolution Model Simulations

NASA Astrophysics Data System (ADS)

Christensen, H. M.; Dawson, A.; Palmer, T.

2017-12-01

Stochastic parametrisations are used in weather and climate models as a physically motivated way to represent model error due to unresolved processes. Designing new stochastic schemes has been the target of much innovative research over the last decade. While a focus has been on developing physically motivated approaches, many successful stochastic parametrisation schemes are very simple, such as the European Centre for Medium-Range Weather Forecasts (ECMWF) multiplicative scheme `Stochastically Perturbed Parametrisation Tendencies' (SPPT). The SPPT scheme improves the skill of probabilistic weather and seasonal forecasts, and so is widely used. However, little work has focused on assessing the physical basis of the SPPT scheme. We address this matter by using high-resolution model simulations to explicitly measure the `error' in the parametrised tendency that SPPT seeks to represent. The high resolution simulations are first coarse-grained to the desired forecast model resolution before they are used to produce initial conditions and forcing data needed to drive the ECMWF Single Column Model (SCM). By comparing SCM forecast tendencies with the evolution of the high resolution model, we can measure the `error' in the forecast tendencies. In this way, we provide justification for the multiplicative nature of SPPT, and for the temporal and spatial scales of the stochastic perturbations. However, we also identify issues with the SPPT scheme. It is therefore hoped these measurements will improve both holistic and process based approaches to stochastic parametrisation. Figure caption: Instantaneous snapshot of the optimal SPPT stochastic perturbation, derived by comparing high-resolution simulations with a low resolution forecast model.

Laser resonance ionization spectroscopy on lutetium for the MEDICIS project

NASA Astrophysics Data System (ADS)

Gadelshin, V.; Cocolios, T.; Fedoseev, V.; Heinke, R.; Kieck, T.; Marsh, B.; Naubereit, P.; Rothe, S.; Stora, T.; Studer, D.; Van Duppen, P.; Wendt, K.

2017-11-01

The MEDICIS-PROMED Innovative Training Network under the Horizon 2020 EU program aims to establish a network of early stage researchers, involving scientific exchange and active cooperation between leading European research institutions, universities, hospitals, and industry. Primary scientific goal is the purpose of providing and testing novel radioisotopes for nuclear medical imaging and radionuclide therapy. Within a closely linked project at CERN, a dedicated electromagnetic mass separator system is presently under installation for production of innovative radiopharmaceutical isotopes at the new CERN-MEDICIS laboratory, directly adjacent to the existing CERN-ISOLDE radioactive ion beam facility. It is planned to implement a resonance ionization laser ion source (RILIS) to ensure high efficiency and unrivaled purity in the production of radioactive ions. To provide a highly efficient ionization process, identification and characterization of a specific multi-step laser ionization scheme for each individual element with isotopes of interest is required. The element lutetium is of primary relevance, and therefore was considered as first candidate. Three two-step excitation schemes for lutetium atoms are presented in this work, and spectroscopic results are compared with data of other authors.

The Social Effects of the Australian Higher Education Contribution Scheme (HECS)

ERIC Educational Resources Information Center

Marks, Gary Neil

2009-01-01

Australia's Higher Education Contribution Scheme (HECS) is an income contingent loan scheme, in which university students pay back part of the costs of their tuition after their post-university income reaches a certain threshold, is an important policy innovation for the financing of higher education. However, its critics claim that HECS increases…

Computer-based creativity enhanced conceptual design model for non-routine design of mechanical systems

NASA Astrophysics Data System (ADS)

Li, Yutong; Wang, Yuxin; Duffy, Alex H. B.

2014-11-01

Computer-based conceptual design for routine design has made great strides, yet non-routine design has not been given due attention, and it is still poorly automated. Considering that the function-behavior-structure(FBS) model is widely used for modeling the conceptual design process, a computer-based creativity enhanced conceptual design model(CECD) for non-routine design of mechanical systems is presented. In the model, the leaf functions in the FBS model are decomposed into and represented with fine-grain basic operation actions(BOA), and the corresponding BOA set in the function domain is then constructed. Choosing building blocks from the database, and expressing their multiple functions with BOAs, the BOA set in the structure domain is formed. Through rule-based dynamic partition of the BOA set in the function domain, many variants of regenerated functional schemes are generated. For enhancing the capability to introduce new design variables into the conceptual design process, and dig out more innovative physical structure schemes, the indirect function-structure matching strategy based on reconstructing the combined structure schemes is adopted. By adjusting the tightness of the partition rules and the granularity of the divided BOA subsets, and making full use of the main function and secondary functions of each basic structure in the process of reconstructing of the physical structures, new design variables and variants are introduced into the physical structure scheme reconstructing process, and a great number of simpler physical structure schemes to accomplish the overall function organically are figured out. The creativity enhanced conceptual design model presented has a dominant capability in introducing new deign variables in function domain and digging out simpler physical structures to accomplish the overall function, therefore it can be utilized to solve non-routine conceptual design problem.

Pricing and reimbursement frameworks in Central Eastern Europe: a decision tool to support choices.

PubMed

Kolasa, Katarzyna; Kalo, Zoltan; Hornby, Edward

2015-02-01

Given limited financial resources in the Central Eastern European (CEE) region, challenges in obtaining access to innovative medical technologies are formidable. The objective of this research was to develop a decision tree that supports decision makers and drug manufacturers from CEE region in their search for optimal innovative pricing and reimbursement scheme (IPRSs). A systematic literature review was performed to search for published IPRSs, and then ten experts from the CEE region were interviewed to ascertain their opinions on these schemes. In total, 33 articles representing 46 unique IPRSs were analyzed. Based on our literature review and subsequent expert input, key decision nodes and branches of the decision tree were developed. The results indicate that outcome-based schemes are better suited to deal with uncertainties surrounding cost effectiveness, while non-outcome-based schemes are more appropriate for pricing and budget impact challenges.

Multi-innovation auto-constructed least squares identification for 4 DOF ship manoeuvring modelling with full-scale trial data.

PubMed

Zhang, Guoqing; Zhang, Xianku; Pang, Hongshuai

2015-09-01

This research is concerned with the problem of 4 degrees of freedom (DOF) ship manoeuvring identification modelling with the full-scale trial data. To avoid the multi-innovation matrix inversion in the conventional multi-innovation least squares (MILS) algorithm, a new transformed multi-innovation least squares (TMILS) algorithm is first developed by virtue of the coupling identification concept. And much effort is made to guarantee the uniformly ultimate convergence. Furthermore, the auto-constructed TMILS scheme is derived for the ship manoeuvring motion identification by combination with a statistic index. Comparing with the existing results, the proposed scheme has the significant computational advantage and is able to estimate the model structure. The illustrative examples demonstrate the effectiveness of the proposed algorithm, especially including the identification application with full-scale trial data. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

Quantum key management

DOEpatents

Hughes, Richard John; Thrasher, James Thomas; Nordholt, Jane Elizabeth

2016-11-29

Innovations for quantum key management harness quantum communications to form a cryptography system within a public key infrastructure framework. In example implementations, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a Merkle signature scheme (using Winternitz one-time digital signatures or other one-time digital signatures, and Merkle hash trees) to constitute a cryptography system. More generally, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a hash-based signature scheme. This provides a secure way to identify, authenticate, verify, and exchange secret cryptographic keys. Features of the quantum key management innovations further include secure enrollment of users with a registration authority, as well as credential checking and revocation with a certificate authority, where the registration authority and/or certificate authority can be part of the same system as a trusted authority for quantum key distribution.

Per-Pixel, Dual-Counter Scheme for Optical Communications

NASA Technical Reports Server (NTRS)

Farr, William H.; Bimbaum, Kevin M.; Quirk, Kevin J.; Sburlan, Suzana; Sahasrabudhe, Adit

2013-01-01

Free space optical communications links from deep space are projected to fulfill future NASA communication requirements for 2020 and beyond. Accurate laser-beam pointing is required to achieve high data rates at low power levels.This innovation is a per-pixel processing scheme using a pair of three-state digital counters to implement acquisition and tracking of a dim laser beacon transmitted from Earth for pointing control of an interplanetary optical communications system using a focal plane array of single sensitive detectors. It shows how to implement dim beacon acquisition and tracking for an interplanetary optical transceiver with a method that is suitable for both achieving theoretical performance, as well as supporting additional functions of high data rate forward links and precision spacecraft ranging.

Space station automation study. Automation requirements derived from space manufacturing concepts. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1984-01-01

The two manufacturing concepts developed represent innovative, technologically advanced manufacturing schemes. The concepts were selected to facilitate an in depth analysis of manufacturing automation requirements in the form of process mechanization, teleoperation and robotics, and artificial intelligence. While the cost effectiveness of these facilities has not been analyzed as part of this study, both appear entirely feasible for the year 2000 timeframe. The growing demand for high quality gallium arsenide microelectronics may warrant the ventures.

Design and practice of a novel experiment teaching system based on the optoelectric information chain

NASA Astrophysics Data System (ADS)

Luo, Yunhan; Chen, Zhe; Li, Yan; Di, Hongwei; Li, Zhen; Bai, Chunhe; Tang, Jieyuan; Zhang, Jun; Yi, Xiao

2017-08-01

The course of optoelectronic information science is a diverse science and technology with wide range of disciplines, intensive technology, and strong applicability. As a result, the practice teaching in undergraduate education occupies the strategic important position, which is a key link in the process of innovative talents cultivation of photoelectric information, plays a unique and irreplaceable role by any other teaching methods. In order to meet the requirements of national innovative talents of photoelectric information, the complete teaching reform strategy was put forward by combining with the higher education policy and development strategy of teaching and professional characteristics. The goal of the experimental teaching reform is to cultivate innovative talents and to construct the photoelectric information industry chain system of experimental teaching platform and cultivating creative personnel. The key clue is the photoelectric information surrounding photoelectric information, like "generation - modulation - transformation - detection - procession" which will be realized by resource integration and complementary among cross disciplines, and focusing on scientific research support for the teaching and the combination of professional knowledge and practical application. This teaching reform scheme presented in the paper will provide very good demonstration effect in the curriculum reform of other photoelectric information related courses.

Formation of the perspective innovation policy of the enterprise in the conditions of organizational-economic changes

NASA Astrophysics Data System (ADS)

Uvarova, Svetlana; Vlasenko, Vyacheslav; Bukreev, Anatoly; Myshovskaya, Ludmila; Kuzina, Olga

2018-03-01

This article is based on the analysis of modern condition and dynamics of innovational development of high-rise buildings construction. A number of cardinal organizational and economic changes in management at the macro and meso-levels is taken into the account. Principal scheme of development of the methodology of formation of perspective innovation politics in high-ruse buildings construction based on inculcation of modern methods of strategic control of innovational activity is suggested in this article.

Study of the undergraduate student's innovation and entrepreneurship training strategy

NASA Astrophysics Data System (ADS)

Sui, Guorong; Liang, Binming; Jia, Hongzhi

2017-08-01

With the development of science and technology, all teachers in the college will face how to stimulate the undergraduate student's ability and make them to be an excellent engineer. For solving these questions, a new scheme with three steps has been designed. First, students will participate in the class teaching activity not only teacher. It will encourage them to read many extracurricular books and articles. Second, they will be required to think and design more new experiments after complete all experiment about the textbook and join more competition of the innovation and entrepreneurship. Third, some students who have more time and ability can early enter into his advisor professor's lab to join various science and technology project. By this scheme, it will be realized to improve student's innovation ability and be a brilliant engineer.

Theoretical and technological building blocks for an innovation accelerator

NASA Astrophysics Data System (ADS)

van Harmelen, F.; Kampis, G.; Börner, K.; van den Besselaar, P.; Schultes, E.; Goble, C.; Groth, P.; Mons, B.; Anderson, S.; Decker, S.; Hayes, C.; Buecheler, T.; Helbing, D.

2012-11-01

Modern science is a main driver of technological innovation. The efficiency of the scientific system is of key importance to ensure the competitiveness of a nation or region. However, the scientific system that we use today was devised centuries ago and is inadequate for our current ICT-based society: the peer review system encourages conservatism, journal publications are monolithic and slow, data is often not available to other scientists, and the independent validation of results is limited. The resulting scientific process is hence slow and sloppy. Building on the Innovation Accelerator paper by Helbing and Balietti [1], this paper takes the initial global vision and reviews the theoretical and technological building blocks that can be used for implementing an innovation (in first place: science) accelerator platform driven by re-imagining the science system. The envisioned platform would rest on four pillars: (i) Redesign the incentive scheme to reduce behavior such as conservatism, herding and hyping; (ii) Advance scientific publications by breaking up the monolithic paper unit and introducing other building blocks such as data, tools, experiment workflows, resources; (iii) Use machine readable semantics for publications, debate structures, provenance etc. in order to include the computer as a partner in the scientific process, and (iv) Build an online platform for collaboration, including a network of trust and reputation among the different types of stakeholders in the scientific system: scientists, educators, funding agencies, policy makers, students and industrial innovators among others. Any such improvements to the scientific system must support the entire scientific process (unlike current tools that chop up the scientific process into disconnected pieces), must facilitate and encourage collaboration and interdisciplinarity (again unlike current tools), must facilitate the inclusion of intelligent computing in the scientific process, must facilitate not only the core scientific process, but also accommodate other stakeholders such science policy makers, industrial innovators, and the general public. We first describe the current state of the scientific system together with up to a dozen new key initiatives, including an analysis of the role of science as an innovation accelerator. Our brief survey will show that there exist many separate ideas and concepts and diverse stand-alone demonstrator systems for different components of the ecosystem with many parts are still unexplored, and overall integration lacking. By analyzing a matrix of stakeholders vs. functionalities, we identify the required innovations. We (non-exhaustively) discuss a few of them: Publications that are meaningful to machines, innovative reviewing processes, data publication, workflow archiving and reuse, alternative impact metrics, tools for the detection of trends, community formation and emergence, as well as modular publications, citation objects and debate graphs. To summarize, the core idea behind the Innovation Accelerator is to develop new incentive models, rules, and interaction mechanisms to stimulate true innovation, revolutionizing the way in which we create knowledge and disseminate information.

Cultivation of students' engineering designing ability based on optoelectronic system course project

NASA Astrophysics Data System (ADS)

Cao, Danhua; Wu, Yubin; Li, Jingping

2017-08-01

We carry out teaching based on optoelectronic related course group, aiming at junior students majored in Optoelectronic Information Science and Engineering. " Optoelectronic System Course Project " is product-designing-oriented and lasts for a whole semester. It provides a chance for students to experience the whole process of product designing, and improve their abilities to search literature, proof schemes, design and implement their schemes. In teaching process, each project topic is carefully selected and repeatedly refined to guarantee the projects with the knowledge integrity, engineering meanings and enjoyment. Moreover, we set up a top team with professional and experienced teachers, and build up learning community. Meanwhile, the communication between students and teachers as well as the interaction among students are taken seriously in order to improve their team-work ability and communicational skills. Therefore, students are not only able to have a chance to review the knowledge hierarchy of optics, electronics, and computer sciences, but also are able to improve their engineering mindset and innovation consciousness.

Introducing Large-Scale Innovation in Schools

NASA Astrophysics Data System (ADS)

Sotiriou, Sofoklis; Riviou, Katherina; Cherouvis, Stephanos; Chelioti, Eleni; Bogner, Franz X.

2016-08-01

Education reform initiatives tend to promise higher effectiveness in classrooms especially when emphasis is given to e-learning and digital resources. Practical changes in classroom realities or school organization, however, are lacking. A major European initiative entitled Open Discovery Space (ODS) examined the challenge of modernizing school education via a large-scale implementation of an open-scale methodology in using technology-supported innovation. The present paper describes this innovation scheme which involved schools and teachers all over Europe, embedded technology-enhanced learning into wider school environments and provided training to teachers. Our implementation scheme consisted of three phases: (1) stimulating interest, (2) incorporating the innovation into school settings and (3) accelerating the implementation of the innovation. The scheme's impact was monitored for a school year using five indicators: leadership and vision building, ICT in the curriculum, development of ICT culture, professional development support, and school resources and infrastructure. Based on about 400 schools, our study produced four results: (1) The growth in digital maturity was substantial, even for previously high scoring schools. This was even more important for indicators such as vision and leadership" and "professional development." (2) The evolution of networking is presented graphically, showing the gradual growth of connections achieved. (3) These communities became core nodes, involving numerous teachers in sharing educational content and experiences: One out of three registered users (36 %) has shared his/her educational resources in at least one community. (4) Satisfaction scores ranged from 76 % (offer of useful support through teacher academies) to 87 % (good environment to exchange best practices). Initiatives such as ODS add substantial value to schools on a large scale.

Returnees and Diaspora as Source of Innovation in Chinese Higher Education

ERIC Educational Resources Information Center

Welch, Anthony; Hao, Jie

2013-01-01

This paper highlights how returnees and knowledge diaspora are important sources for China's human resources development, identifying push and pull factors that also contribute significantly to innovation in the higher education sector. By outlining China's key projects and schemes for recruiting international professional workers, the paper…

Advanced Entry Adult Apprenticeship Training Scheme: A Case Study

ERIC Educational Resources Information Center

Sparks, Alan; Ingram, Hadyn; Phillips, Sunny

2009-01-01

Purpose: The purpose of this paper is to evaluate an innovative way to train adult apprentices for the construction industry. Design/methodology/approach: The paper emphasizes that, in order to address skills shortages for international construction, training methods must be improved. It looks at the example of an adult apprenticeship scheme in…

An Innovative Approach to Scheme Learning Map Considering Tradeoff Multiple Objectives

ERIC Educational Resources Information Center

Lin, Yu-Shih; Chang, Yi-Chun; Chu, Chih-Ping

2016-01-01

An important issue in personalized learning is to provide learners with customized learning according to their learning characteristics. This paper focused attention on scheming learning map as follows. The learning goal can be achieved via different pathways based on alternative materials, which have the relationships of prerequisite, dependence,…

Evaluation of Future Blogs. Final Report

ERIC Educational Resources Information Center

Haines, Ben; Straw, Suzanne

2008-01-01

Future Blogs was developed through collaboration between the Royal Society of Chemistry and The Brightside Trust. It is an innovative e-mentoring scheme that links pupils studying chemistry with mentors from universities or industry and is based on the Bright Journals e-mentoring programme (an e-mentoring scheme targeted at 14-18 year olds…

Expanding health insurance scheme in the informal sector in Nigeria: awareness as a potential demand-side tool

PubMed Central

Adewole, David Ayobami; Akanbi, Saidat Abisola; Osungbade, Kayode Omoniyi; Bello, Segun

2017-01-01

Introduction The implementation and expansion of a health insurance scheme in the informal sector, particularly in developing countries, is a challenge. With the aid of an innovative Information-Education and Communication model, titled 'Understanding the concept of health insurance: An innovative social marketing tool', an assessment of the awareness and perception of the scheme among market women was carried out. Methods This is a cross-sectional descriptive survey, carried out among market women in Ibadan, Nigeria. In a multi-stage sampling technique, a total of 351 women were interviewed using an interviewer-administered, semi-structured questionnaire. The data was analysed using SPSS version 16. Chi-square test was used to test associations between selected variables of interest. Logistic regression model was used to determine predictors of awareness of the National Health Insurance Scheme (NHIS). A model controlling for participants' enrolment status was built and Adjusted Odds Ratio (AOR) reported. Level of statistical significance was set at p < 0.05. Results A total of 344 market women aged 18 years and above participated in the study, a response rate of 98.0%. Respondents' educational status was the only predictor significantly associated with awareness of the NHIS. Respondents with post-primary education had 10 times the odds of being aware of the NHIS than respondents with no education or only primary education (Adjusted Odds Ratio = 10.3; 95% CI = 4.1-26.0). Conclusion Innovative models to enable potential beneficiaries, especially among the informal sector, to better comprehend and accept the concept of prepayment methods of financing healthcare costs is important in efforts to implement and expand a social health insurance scheme. PMID:28819474

Gamma beams generation with high intensity lasers for two photon Breit-Wheeler pair production

NASA Astrophysics Data System (ADS)

D'Humieres, Emmanuel; Ribeyre, Xavier; Jansen, Oliver; Esnault, Leo; Jequier, Sophie; Dubois, Jean-Luc; Hulin, Sebastien; Tikhonchuk, Vladimir; Arefiev, Alex; Toncian, Toma; Sentoku, Yasuhiko

2017-10-01

Linear Breit-Wheeler pair creation is the lowest threshold process in photon-photon interaction, controlling the energy release in Gamma Ray Bursts and Active Galactic Nuclei, but it has never been directly observed in the laboratory. Using numerical simulations, we demonstrate the possibility to produce collimated gamma beams with high energy conversion efficiency using high intensity lasers and innovative targets. When two of these beams collide at particular angles, our analytical calculations demonstrate a beaming effect easing the detection of the pairs in the laboratory. This effect has been confirmed in photon collision simulations using a recently developed innovative algorithm. An alternative scheme using Bremsstrahlung radiation produced by next generation high repetition rate laser systems is also being explored and the results of first optimization campaigns in this regime will be presented.

Adoption of a High-Impact Innovation in a Homogeneous Population.

PubMed

Weiss, Curtis H; Poncela-Casasnovas, Julia; Glaser, Joshua I; Pah, Adam R; Persell, Stephen D; Baker, David W; Wunderink, Richard G; Nunes Amaral, Luís A

2014-10-15

Adoption of innovations, whether new ideas, technologies, or products, is crucially important to knowledge societies. The landmark studies of adoption dealt with innovations having great societal impact (such as antibiotics or hybrid crops) but where determining the utility of the innovation was straightforward (such as fewer side effects or greater yield). Recent large-scale studies of adoption were conducted within heterogeneous populations and focused on products with little societal impact. Here, we focus on a case with great practical significance: adoption by small groups of highly trained individuals of innovations with large societal impact but for which it is impractical to determine the true utility of the innovation. Specifically, we study experimentally the adoption by critical care physicians of a diagnostic assay that complements current protocols for the diagnosis of life-threatening bacterial infections and for which a physician cannot estimate the true accuracy of the assay based on personal experience. We show through computational modeling of the experiment that infection-spreading models-which have been formalized as generalized contagion processes-are not consistent with the experimental data, while a model inspired by opinion models is able to reproduce the empirical data. Our modeling approach enables us to investigate the efficacy of different intervention schemes on the rate and robustness of innovation adoption in the real world. While our study is focused on critical care physicians, our findings have implications for other settings in education, research, and business, where small groups of highly qualified peers make decisions about the adoption of innovations whose utility is difficult if not impossible to gauge.

A pragmatic randomised controlled trial of the Welsh National Exercise Referral Scheme: protocol for trial and integrated economic and process evaluation.

PubMed

Murphy, Simon; Raisanen, Larry; Moore, Graham; Edwards, Rhiannon Tudor; Linck, Pat; Williams, Nefyn; Ud Din, Nafees; Hale, Janine; Roberts, Chris; McNaish, Elaine; Moore, Laurence

2010-06-18

The benefits to health of a physically active lifestyle are well established and there is evidence that a sedentary lifestyle plays a significant role in the onset and progression of chronic disease. Despite a recognised need for effective public health interventions encouraging sedentary people with a medical condition to become more active, there are few rigorous evaluations of their effectiveness. Following NICE guidance, the Welsh national exercise referral scheme was implemented within the context of a pragmatic randomised controlled trial. The randomised controlled trial, with nested economic and process evaluations, recruited 2,104 inactive men and women aged 16+ with coronary heart disease (CHD) risk factors and/or mild to moderate depression, anxiety or stress. Participants were recruited from 12 local health boards in Wales and referred directly by health professionals working in a range of health care settings. Consenting participants were randomised to either a 16 week tailored exercise programme run by qualified exercise professionals at community sports centres (intervention), or received an information booklet on physical activity (control). A range of validated measures assessing physical activity, mental health, psycho-social processes and health economics were administered at 6 and 12 months, with the primary 12 month outcome measure being 7 day Physical Activity Recall. The process evaluation explored factors determining the effectiveness or otherwise of the scheme, whilst the economic evaluation determined the relative cost-effectiveness of the scheme in terms of public spending. Evaluation of such a large scale national public health intervention presents methodological challenges in terms of trial design and implementation. This study was facilitated by early collaboration with social research and policy colleagues to develop a rigorous design which included an innovative approach to patient referral and trial recruitment, a comprehensive process evaluation examining intervention delivery and an integrated economic evaluation. This will allow a unique insight into the feasibility, effectiveness and cost effectiveness of a national exercise referral scheme for participants with CHD risk factors or mild to moderate anxiety, depression, or stress and provides a potential model for future policy evaluations. Current Controlled Trials ISRCTN47680448.

Innovative hazard detection and avoidance strategy for autonomous safe planetary landing

NASA Astrophysics Data System (ADS)

Jiang, Xiuqiang; Li, Shuang; Tao, Ting

2016-09-01

Autonomous hazard detection and avoidance (AHDA) is one of the key technologies for future safe planetary landing missions. In this paper, we address the latest progress on planetary autonomous hazard detection and avoidance technologies. First, the innovative autonomous relay hazard detection and avoidance strategy adopted in Chang'e-3 lunar soft landing mission and its flight results are reported in detail. Second, two new conceptual candidate schemes of hazard detection and avoidance are presented based on the Chang'e-3 AHDA system and the latest developing technologies for the future planetary missions, and some preliminary testing results are also given. Finally, the related supporting technologies for the two candidate schemes above are analyzed.

Improving Attendance and Punctuality of FE Basic Skill Students through an Innovative Scheme

ERIC Educational Resources Information Center

Ade-Ojo, Gordon O.

2005-01-01

This paper reports the findings of a study set up to establish the impact of a particular scheme on the attendance and punctuality performance of a group of Basic Skills learners against the backdrop of various theoretical postulations on managing undesirable behavior. Data collected on learners' performance was subjected to statistical analysis…

Success without "A" Pass: An Educational Experiment Revisited

ERIC Educational Resources Information Center

Nash, Mary

2011-01-01

In 1963, the University of Sussex inaugurated an innovative Early Leavers Scheme in response to two government reports which confirmed that it was still the norm for talented working-class children to leave school aged 15 or 16 and indicated that the hopes of the 1944 Education Act were as yet unfulfilled. This article explores what the scheme has…

Innovation in diagnostic imaging services: assessing the potential for value-based reimbursement.

PubMed

Garrison, Louis P; Bresnahan, Brian W; Higashi, Mitchell K; Hollingworth, William; Jarvik, Jeffrey G

2011-09-01

Innovation in the field of diagnostic imaging is based primarily on the availability of new and improved equipment that opens the door for new clinical applications. Payments for these imaging procedures are subject to complex Medicare price control schemes, affecting incentives for appropriate use and innovation. Achieving a "dynamically efficient" health care system-one that elicits a socially optimal amount of innovation-requires that innovators be rewarded in relation to the value they add and can demonstrate with evidence. The authors examine how and whether value-based reimbursement for diagnostic imaging services might better reward innovation explicitly for expected improvements in health and economic outcomes. Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.

MixDroid: A multi-features and multi-classifiers bagging system for Android malware detection

NASA Astrophysics Data System (ADS)

Huang, Weiqing; Hou, Erhang; Zheng, Liang; Feng, Weimiao

2018-05-01

In the past decade, Android platform has rapidly taken over the mobile market for its superior convenience and open source characteristics. However, with the popularity of Android, malwares targeting on Android devices are increasing rapidly, while the conventional rule-based and expert-experienced approaches are no longer able to handle such explosive growth. In this paper, combining with the theory of natural language processing and machine learning, we not only implement the basic feature extraction of permission application features, but also propose two innovative schemes of feature extraction: Dalvik opcode features and malicious code image, and implement an automatic Android malware detection system MixDroid which is based on multi-features and multi-classifiers. According to our experiment results on 20,000 Android applications, detection accuracy of MixDroid is 98.1%, which proves our schemes' effectiveness in Android malware detection.

Stakeholders Perspectives on the Success Drivers in Ghana’s National Health Insurance Scheme – Identifying Policy Translation Issues

PubMed Central

Fusheini, Adam; Marnoch, Gordon; Gray, Ann Marie

2017-01-01

Background: Ghana’s National Health Insurance Scheme (NHIS), established by an Act of Parliament (Act 650), in 2003 and since replaced by Act 852 of 2012 remains, in African terms, unprecedented in terms of growth and coverage. As a result, the scheme has received praise for its associated legal reforms, clinical audit mechanisms and for serving as a hub for knowledge sharing and learning within the context of South-South cooperation. The scheme continues to shape national health insurance thinking in Africa. While the success, especially in coverage and financial access has been highlighted by many authors, insufficient attention has been paid to critical and context-specific factors. This paper seeks to fill that gap. Methods: Based on an empirical qualitative case study of stakeholders’ views on challenges and success factors in four mutual schemes (district offices) located in two regions of Ghana, the study uses the concept of policy translation to assess whether the Ghana scheme could provide useful lessons to other African and developing countries in their quest to implement social/NHISs. Results: In the study, interviewees referred to both ‘hard and soft’ elements as driving the "success" of the Ghana scheme. The main ‘hard elements’ include bureaucratic and legal enforcement capacities; IT; financing; governance, administration and management; regulating membership of the scheme; and service provision and coverage capabilities. The ‘soft’ elements identified relate to: the background/context of the health insurance scheme; innovative ways of funding the NHIS, the hybrid nature of the Ghana scheme; political will, commitment by government, stakeholders and public cooperation; social structure of Ghana (solidarity); and ownership and participation. Conclusion: Other developing countries can expect to translate rather than re-assemble a national health insurance programme in an incomplete and highly modified form over a period of years, amounting to a process best conceived as germination as opposed to emulation. The Ghana experience illustrates that in adopting health financing systems that function well, countries need to customise systems (policy customisation) to suit their socio-economic, political and administrative settings. Home-grown health financing systems that resonate with social values will also need to be found in the process of translation PMID:28812815

Equity and service innovation: the implementation of a bibliotherapy scheme in Wales.

PubMed

Porter, Alison; Peconi, Julie; Evans, Angela; Snooks, Helen; Lloyd, Keith; Russell, Ian

2008-04-01

Book Prescription Wales (BPW) is a pilot bibiliotherapy scheme launched in July 2005 as a primary care treatment option for people with mild to moderate mental health problems. In an innovative model, patients are prescribed self-help books from a list, to borrow from local libraries. Our objective was to evaluate its implementation, focusing on the issue of equity of service delivery. Data were gathered from Welsh Assembly Government concerning project set-up and borrowing rates. Mailed questionnaires were completed by 21/22 (95.4%) Local Health Boards and 44/64 (68.8%) Community Mental Health Teams. In addition, 327 out of 497 (66%) primary care practices were surveyed by telephone, 20 prescribers took part in in-depth telephone interviews and three focus groups were conducted with library staff. From July 2005-March 2006, books were borrowed 15,236 times. There was a 10-fold variation in borrowing rates across local authorities (1.07 to 10.18 loans/1000 people). The priority which Local Health Board staff reported giving to the scheme varied. Uptake among prescribers was mixed: in 35% of general practices (n = 116) no-one participated. Prescribers reported different ways of using the bibliotherapy scheme. Library staff reported issues of patchy uptake. Variation in usage of bibliotherapy raises questions about equity; it is unlikely to reflect the distribution of people who could potentially benefit. Factors influencing variation existed all along the implementation chain. It is not always possibly to separate demand-side and supply-side factors when considering equity and service innovation in health care.

Note: innovative demodulation scheme for coherent detectors in cosmic microwave background experiments.

PubMed

Ishidoshiro, K; Chinone, Y; Hasegawa, M; Hazumi, M; Nagai, M; Tajima, O

2012-05-01

We propose an innovative demodulation scheme for coherent detectors used in cosmic microwave background polarization experiments. Removal of non-white noise, e.g., narrow-band noise, in detectors is one of the key requirements for the experiments. A combination of modulation and demodulation is used to extract polarization signals as well as to suppress such noise. Traditional demodulation, which is based on the two-point numerical differentiation, works as a first-order high pass filter for the noise. The proposed demodulation is based on the three-point numerical differentiation. It works as a second-order high pass filter. By using a real detector, we confirmed significant improvements of suppression power for the narrow-band noise. We also found improvement of the noise floor.

Pricing and reimbursement of in-patent drugs in seven European countries: a comparative analysis.

PubMed

Garattini, Livio; Cornago, Dante; De Compadri, Paola

2007-08-01

The main objective of this comparative analysis was to assess regulations applied by EU governments to reward potentially innovative drugs. We focused on the pharmaceutical policy for in-patent drugs in seven EU countries: Belgium, France, Germany, Italy, the Netherlands, Spain, and the UK. A common scheme was applied to all seven countries: first, pricing and reimbursement procedures for new and innovative drugs were investigated; secondly, we focused on the use in the regulatory process of economic evaluations. The analysis involved reviewing the literature and interviewing a selected panel of local experts in each country. According to our comparative analysis, a first sensible step might be to classify active ingredients as those addressing neglected pathologies and those for diseases that are already successfully treated, thus offering more limited therapeutic gains by definition. A reasonable solution to reward real innovation could be to admit a premium price for very innovative drugs according to their estimated cost-effectiveness. New drugs with modest improvement could be grouped in therapeutic clusters and submitted to a common reference price, despite patent expiration. Such a "dual approach" could be a sensible compromise to restrict pharmaceutical expenditure while at the same time rewarding companies that invest in high-risk basic research.

LEAP: An Innovative Direction Dependent Ionospheric Calibration Scheme for Low Frequency Arrays

NASA Astrophysics Data System (ADS)

Rioja, María J.; Dodson, Richard; Franzen, Thomas M. O.

2018-05-01

The ambitious scientific goals of the SKA require a matching capability for calibration of atmospheric propagation errors, which contaminate the observed signals. We demonstrate a scheme for correcting the direction-dependent ionospheric and instrumental phase effects at the low frequencies and with the wide fields of view planned for SKA-Low. It leverages bandwidth smearing, to filter-out signals from off-axis directions, allowing the measurement of the direction-dependent antenna-based gains in the visibility domain; by doing this towards multiple directions it is possible to calibrate across wide fields of view. This strategy removes the need for a global sky model, therefore all directions are independent. We use MWA results at 88 and 154 MHz under various weather conditions to characterise the performance and applicability of the technique. We conclude that this method is suitable to measure and correct for temporal fluctuations and direction-dependent spatial ionospheric phase distortions on a wide range of scales: both larger and smaller than the array size. The latter are the most intractable and pose a major challenge for future instruments. Moreover this scheme is an embarrassingly parallel process, as multiple directions can be processed independently and simultaneously. This is an important consideration for the SKA, where the current planned architecture is one of compute-islands with limited interconnects. Current implementation of the algorithm and on-going developments are discussed.

Incentivising effort in governance of public hospitals: Development of a delegation-based alternative to activity-based remuneration.

PubMed

Søgaard, Rikke; Kristensen, Søren Rud; Bech, Mickael

2015-08-01

This paper is a first examination of the development of an alternative to activity-based remuneration in public hospitals, which is currently being tested at nine hospital departments in a Danish region. The objective is to examine the process of delegating the authority of designing new incentive schemes from the principal (the regional government) to the agents (the hospital departments). We adopt a theoretical framework where, when deciding about delegation, the principal should trade off an initiative effect against the potential cost of loss of control. The initiative effect is evaluated by studying the development process and the resulting incentive schemes for each of the departments. Similarly, the potential cost of loss of control is evaluated by assessing the congruence between focus of the new incentive schemes and the principal's objectives. We observe a high impact of the effort incentive in the form of innovative and ambitious selection of projects by the agents, leading to nine very different solutions across departments. However, we also observe some incongruence between the principal's stated objectives and the revealed private interests of the agents. Although this is a baseline study involving high uncertainty about the future, the findings point at some issues with the delegation approach that could lead to inefficient outcomes. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Topology of Innovation Spaces in the Knowledge Networks Emerging through Questions-And-Answers

PubMed Central

Andjelković, Miroslav; Tadić, Bosiljka; Mitrović Dankulov, Marija; Rajković, Milan; Melnik, Roderick

2016-01-01

The communication processes of knowledge creation represent a particular class of human dynamics where the expertise of individuals plays a substantial role, thus offering a unique possibility to study the structure of knowledge networks from online data. Here, we use the empirical evidence from questions-and-answers in mathematics to analyse the emergence of the network of knowledge contents (or tags) as the individual experts use them in the process. After removing extra edges from the network-associated graph, we apply the methods of algebraic topology of graphs to examine the structure of higher-order combinatorial spaces in networks for four consecutive time intervals. We find that the ranking distributions of the suitably scaled topological dimensions of nodes fall into a unique curve for all time intervals and filtering levels, suggesting a robust architecture of knowledge networks. Moreover, these networks preserve the logical structure of knowledge within emergent communities of nodes, labeled according to a standard mathematical classification scheme. Further, we investigate the appearance of new contents over time and their innovative combinations, which expand the knowledge network. In each network, we identify an innovation channel as a subgraph of triangles and larger simplices to which new tags attach. Our results show that the increasing topological complexity of the innovation channels contributes to network’s architecture over different time periods, and is consistent with temporal correlations of the occurrence of new tags. The methodology applies to a wide class of data with the suitable temporal resolution and clearly identified knowledge-content units. PMID:27171149

Robust detection, isolation and accommodation for sensor failures

NASA Technical Reports Server (NTRS)

Emami-Naeini, A.; Akhter, M. M.; Rock, S. M.

1986-01-01

The objective is to extend the recent advances in robust control system design of multivariable systems to sensor failure detection, isolation, and accommodation (DIA), and estimator design. This effort provides analysis tools to quantify the trade-off between performance robustness and DIA sensitivity, which are to be used to achieve higher levels of performance robustness for given levels of DIA sensitivity. An innovations-based DIA scheme is used. Estimators, which depend upon a model of the process and process inputs and outputs, are used to generate these innovations. Thresholds used to determine failure detection are computed based on bounds on modeling errors, noise properties, and the class of failures. The applicability of the newly developed tools are demonstrated on a multivariable aircraft turbojet engine example. A new concept call the threshold selector was developed. It represents a significant and innovative tool for the analysis and synthesis of DiA algorithms. The estimators were made robust by introduction of an internal model and by frequency shaping. The internal mode provides asymptotically unbiased filter estimates.The incorporation of frequency shaping of the Linear Quadratic Gaussian cost functional modifies the estimator design to make it suitable for sensor failure DIA. The results are compared with previous studies which used thresholds that were selcted empirically. Comparison of these two techniques on a nonlinear dynamic engine simulation shows improved performance of the new method compared to previous techniques

Could the employment-based targeting approach serve Egypt in moving towards a social health insurance model?

PubMed

Shawky, S

2010-06-01

The current health insurance system in Egypt targets the productive population through an employment-based scheme bounded by a cost ceiling and focusing on curative care. Egypt Social Contract Survey data from 2005 were used to evaluate the impact of the employment-based scheme on health system accessibility and financing. Only 22.8% of the population in the productive age range (19-59 years) benefited from any health insurance scheme. The employment-based scheme covered 39.3% of the working population and was skewed towards urban areas, older people, females and the wealthier. It did not increase service utilization, but reduced out-of-pocket expenditure. Egypt should blend all health insurance schemes and adopt an innovative approach to reach universal coverage.

Harvesting model uncertainty for the simulation of interannual variability

NASA Astrophysics Data System (ADS)

Misra, Vasubandhu

2009-08-01

An innovative modeling strategy is introduced to account for uncertainty in the convective parameterization (CP) scheme of a coupled ocean-atmosphere model. The methodology involves calling the CP scheme several times at every given time step of the model integration to pick the most probable convective state. Each call of the CP scheme is unique in that one of its critical parameter values (which is unobserved but required by the scheme) is chosen randomly over a given range. This methodology is tested with the relaxed Arakawa-Schubert CP scheme in the Center for Ocean-Land-Atmosphere Studies (COLA) coupled general circulation model (CGCM). Relative to the control COLA CGCM, this methodology shows improvement in the El Niño-Southern Oscillation simulation and the Indian summer monsoon precipitation variability.

Sequential updating of multimodal hydrogeologic parameter fields using localization and clustering techniques

NASA Astrophysics Data System (ADS)

Sun, Alexander Y.; Morris, Alan P.; Mohanty, Sitakanta

2009-07-01

Estimated parameter distributions in groundwater models may contain significant uncertainties because of data insufficiency. Therefore, adaptive uncertainty reduction strategies are needed to continuously improve model accuracy by fusing new observations. In recent years, various ensemble Kalman filters have been introduced as viable tools for updating high-dimensional model parameters. However, their usefulness is largely limited by the inherent assumption of Gaussian error statistics. Hydraulic conductivity distributions in alluvial aquifers, for example, are usually non-Gaussian as a result of complex depositional and diagenetic processes. In this study, we combine an ensemble Kalman filter with grid-based localization and a Gaussian mixture model (GMM) clustering techniques for updating high-dimensional, multimodal parameter distributions via dynamic data assimilation. We introduce innovative strategies (e.g., block updating and dimension reduction) to effectively reduce the computational costs associated with these modified ensemble Kalman filter schemes. The developed data assimilation schemes are demonstrated numerically for identifying the multimodal heterogeneous hydraulic conductivity distributions in a binary facies alluvial aquifer. Our results show that localization and GMM clustering are very promising techniques for assimilating high-dimensional, multimodal parameter distributions, and they outperform the corresponding global ensemble Kalman filter analysis scheme in all scenarios considered.

Japan's long-term care policy for older people: the emergence of innovative "mobilisation" initiatives following the 2005 reforms.

PubMed

Hayashi, Mayumi

2015-04-01

Japan leads the global race for solutions to the increasing long-term care demand from an ageing population. Initial responses in 2000 saw the launch of the public Long-Term Care Insurance (LTCI) system which witnessed an unexpectedly substantial uptake - with doubts raised about financial viability and sustainability. The post-2005 LTCI reform led to the adoption of innovations - including the "mobilisation" of active, older volunteers to support their frailer peers. This strategy, within the wider government's "2025 Vision" to provide total care for the entire older population, sought to secure financial viability and sustainability. Drawing on qualitative in-depth interviews with 21 provider organisations this study will examine three "mobilisation" schemes and identify those factors contributing to overall strengths while acknowledging complexities, diversities and challenges the schemes encountered. Initial literature written by mobilisation proponents may have been overly optimistic: this study seeks to balance such views through providing an understanding and analysis of these mobilisation schemes' realities. The findings will provide insights and suggest more caution to policy-makers intending to promote such schemes - in both Japan and in countries considering doing so. Furthermore, more evaluation is required to obtain evidence to support financial feasibility and sustainability. Copyright © 2015 Elsevier Inc. All rights reserved.

An assessment of innovative pricing schemes for the communication of value: is price discrimination and two-part pricing a way forward?

PubMed

Hertzman, Peter; Miller, Paul; Tolley, Keith

2018-02-01

With the introduction of new expensive medicines, traditional pricing schemes based on constructs such as price per pill/vial have been challenged. Potential innovative schemes could be either financial-based or performance-based. Within financial-based schemes the use of price discrimination is an emerging option, which we explore in this assessment. Areas covered: In the short term the price per indication approach is likely to become more prevalent for high cost, high benefit new pharmaceuticals, such as those emerging in oncology (e.g. new combination immunotherapies). 'Two-Part Pricing' (2PP) is a frequently used payment method in other industries, which consists of an Entry Fee, giving the buyer the right to use the product, and a Usage Price charged every time the product is purchased. Introducing 2PP into biopharma could have cross-stakeholder benefits including broader patient access, and improvement in budget/revenue predictability. A concern however is the potential complexity of the negotiation between manufacturer and payer. Expert commentary: We believe 'price discrimination' and 2PP in particular can be relevant for some new, expensive specialist medicines. A recommended first step would be to initiate pilots to test to what degree the 2PP approach meets stakeholder objectives and is practical to implement within specialty care.

Stakeholders Perspectives on the Success Drivers in Ghana's National Health Insurance Scheme - Identifying Policy Translation Issues.

PubMed

Fusheini, Adam; Marnoch, Gordon; Gray, Ann Marie

2016-10-01

Ghana's National Health Insurance Scheme (NHIS), established by an Act of Parliament (Act 650), in 2003 and since replaced by Act 852 of 2012 remains, in African terms, unprecedented in terms of growth and coverage. As a result, the scheme has received praise for its associated legal reforms, clinical audit mechanisms and for serving as a hub for knowledge sharing and learning within the context of South-South cooperation. The scheme continues to shape national health insurance thinking in Africa. While the success, especially in coverage and financial access has been highlighted by many authors, insufficient attention has been paid to critical and context-specific factors. This paper seeks to fill that gap. Based on an empirical qualitative case study of stakeholders' views on challenges and success factors in four mutual schemes (district offices) located in two regions of Ghana, the study uses the concept of policy translation to assess whether the Ghana scheme could provide useful lessons to other African and developing countries in their quest to implement social/NHISs. In the study, interviewees referred to both 'hard and soft' elements as driving the "success" of the Ghana scheme. The main 'hard elements' include bureaucratic and legal enforcement capacities; IT; financing; governance, administration and management; regulating membership of the scheme; and service provision and coverage capabilities. The 'soft' elements identified relate to: the background/context of the health insurance scheme; innovative ways of funding the NHIS, the hybrid nature of the Ghana scheme; political will, commitment by government, stakeholders and public cooperation; social structure of Ghana (solidarity); and ownership and participation. Other developing countries can expect to translate rather than re-assemble a national health insurance programme in an incomplete and highly modified form over a period of years, amounting to a process best conceived as germination as opposed to emulation. The Ghana experience illustrates that in adopting health financing systems that function well, countries need to customise systems (policy customisation) to suit their socio-economic, political and administrative settings. Home-grown health financing systems that resonate with social values will also need to be found in the process of translation. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Pesticide removal from waste spray-tank water by organoclay adsorption after field application: an approach for a formulation of cyprodinil containing antifoaming/defoaming agents.

PubMed

Suciu, Nicoleta A; Ferrari, Tommaso; Ferrari, Federico; Trevisan, Marco; Capri, Ettore

2012-05-01

Many reports on purification of water containing pesticides are based on studies using unformulated active ingredients. However, most commercial formulations contain additives/adjuvants or are manufactured using microencapsulation which may influence the purification process. Therefore, the main objective of this work was to develop and test a pilot scheme for decontaminating water containing pesticides formulated with antifoaming/defoaming agents. The Freundlich adsorption coefficients of formulation of cyprodinil, a new-generation fungicide, onto the organoclay Cloisite 20A have been determined in the laboratory in order to predict the efficiency of this organoclay in removing the fungicide from waste spray-tank water. Subsequently, the adsorption tests were repeated in the pilot system in order to test the practical operation of the purification scheme. The laboratory adsorption tests successfully predicted the efficiency of the pilot purification system, which removed more than 96% cyprodinil over a few hours. The passing of the organoclay-cyprodinil suspension through a layer of biomass gave 100% recovery of the organoclay at the surface of the biomass after 1 week. The organoclay was composted after the treatment to try to break down the fungicide so as to allow safe disposal of the waste, but cyprodinil was not significantly dissipated after 90 days. The purification scheme proved to be efficient for decontaminating water containing cyprodinil formulated with antifoaming/defoaming agents, but additional treatments for the adsorbed residues still appear to be necessary even for a moderately persistent pesticide such as cyprodinil. Furthermore, a significant conclusion of this study concerns the high influence of pesticide formulations on the process of purification of water containing these compounds, which should be taken into account when developing innovative decontamination schemes, especially for practical applications.

Consolidating the social health insurance schemes in China: towards an equitable and efficient health system.

PubMed

Meng, Qingyue; Fang, Hai; Liu, Xiaoyun; Yuan, Beibei; Xu, Jin

2015-10-10

Fragmentation in social health insurance schemes is an important factor for inequitable access to health care and financial protection for people covered by different health insurance schemes in China. To fulfil its commitment of universal health coverage by 2020, the Chinese Government needs to prioritise addressing this issue. After analysing the situation of fragmentation, this Review summarises efforts to consolidate health insurance schemes both in China and internationally. Rural migrants, elderly people, and those with non-communicable diseases in China will greatly benefit from consolidation of the existing health insurance schemes with extended funding pools, thereby narrowing the disparities among health insurance schemes in fund level and benefit package. Political commitments, institutional innovations, and a feasible implementation plan are the major elements needed for success in consolidation. Achievement of universal health coverage in China needs systemic strategies including consolidation of the social health insurance schemes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Network coding based joint signaling and dynamic bandwidth allocation scheme for inter optical network unit communication in passive optical networks

NASA Astrophysics Data System (ADS)

Wei, Pei; Gu, Rentao; Ji, Yuefeng

2014-06-01

As an innovative and promising technology, network coding has been introduced to passive optical networks (PON) in recent years to support inter optical network unit (ONU) communication, yet the signaling process and dynamic bandwidth allocation (DBA) in PON with network coding (NC-PON) still need further study. Thus, we propose a joint signaling and DBA scheme for efficiently supporting differentiated services of inter ONU communication in NC-PON. In the proposed joint scheme, the signaling process lays the foundation to fulfill network coding in PON, and it can not only avoid the potential threat to downstream security in previous schemes but also be suitable for the proposed hybrid dynamic bandwidth allocation (HDBA) scheme. In HDBA, a DBA cycle is divided into two sub-cycles for applying different coding, scheduling and bandwidth allocation strategies to differentiated classes of services. Besides, as network traffic load varies, the entire upstream transmission window for all REPORT messages slides accordingly, leaving the transmission time of one or two sub-cycles to overlap with the bandwidth allocation calculation time at the optical line terminal (the OLT), so that the upstream idle time can be efficiently eliminated. Performance evaluation results validate that compared with the existing two DBA algorithms deployed in NC-PON, HDBA demonstrates the best quality of service (QoS) support in terms of delay for all classes of services, especially guarantees the end-to-end delay bound of high class services. Specifically, HDBA can eliminate queuing delay and scheduling delay of high class services, reduce those of lower class services by at least 20%, and reduce the average end-to-end delay of all services over 50%. Moreover, HDBA also achieves the maximum delay fairness between coded and uncoded lower class services, and medium delay fairness for high class services.

Can Children Enhance Their Family's Health Knowledge? An Infectious Disease Prevention Program.

PubMed

Sedighi, Iraj; Nouri, Shahla; Sadrosadat, Taravat; Nemati, Reza; Shahbazi, Mojgan

2012-12-01

The purpose of this study is to propose an innovative method of knowledge transfer that aims to improve health literacy about pediatric infectious diseases prevention in families. Children have an appreciable role in this scheme. This study is a before and after trial that has been conducted in Hamedan in 2009. After changing seven infectious disease topics into childish poems, we selected five kindergartens randomly and taught these poetries to the children. Teaching process held after a pretest containing 24 questions that examined 103 of parents about mentioned topics. The same post-test was given after 4 months of teaching process. The mean of correct answers to the pretest was 59.22% comparable with 81.00% for post-test (P<0.00). Gender and knowledge degree could not change the results significantly. Assuming one's correct answers to the questions as his/her Knowledge Mark, the mean of this variable increased to 5.32 by this method. This cost-effective and joyful method had successful results in promoting health knowledge. Children are able to play an active role in family's health situation. Learning within family atmosphere without any obligations makes our scheme a solution for paving the knowledge transferring way.

Sharing risk between payer and provider by leasing health technologies: an affordable and effective reimbursement strategy for innovative technologies?

PubMed

Edlin, Richard; Hall, Peter; Wallner, Klemens; McCabe, Christopher

2014-06-01

The challenge of implementing high-cost innovative technologies in health care systems operating under significant budgetary pressure has led to a radical shift in the health technology reimbursement landscape. New reimbursement strategies attempt to reduce the risk of making the wrong decision, that is, paying for a technology that is not good value for the health care system, while promoting the adoption of innovative technologies into clinical practice. The remaining risk, however, is not shared between the manufacturer and the health care payer at the individual purchase level; it continues to be passed from the manufacturer to the payer at the time of purchase. In this article, we propose a health technology payment strategy-technology leasing reimbursement scheme-that allows the sharing of risk between the manufacturer and the payer: the replacing of up-front payments with a stream of payments spread over the expected duration of benefit from the technology, subject to the technology delivering the claimed health benefit. Using trastuzumab (Herceptin) in early breast cancer as an exemplar technology, we show how a technology leasing reimbursement scheme not only reduces the total budgetary impact of the innovative technology but also truly shares risk between the manufacturer and the health care system, while reducing the value of further research and thus promoting the rapid adoption of innovative technologies into clinical practice. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Birkhoffian symplectic algorithms derived from Hamiltonian symplectic algorithms

NASA Astrophysics Data System (ADS)

Xin-Lei, Kong; Hui-Bin, Wu; Feng-Xiang, Mei

2016-01-01

In this paper, we focus on the construction of structure preserving algorithms for Birkhoffian systems, based on existing symplectic schemes for the Hamiltonian equations. The key of the method is to seek an invertible transformation which drives the Birkhoffian equations reduce to the Hamiltonian equations. When there exists such a transformation, applying the corresponding inverse map to symplectic discretization of the Hamiltonian equations, then resulting difference schemes are verified to be Birkhoffian symplectic for the original Birkhoffian equations. To illustrate the operation process of the method, we construct several desirable algorithms for the linear damped oscillator and the single pendulum with linear dissipation respectively. All of them exhibit excellent numerical behavior, especially in preserving conserved quantities. Project supported by the National Natural Science Foundation of China (Grant No. 11272050), the Excellent Young Teachers Program of North China University of Technology (Grant No. XN132), and the Construction Plan for Innovative Research Team of North China University of Technology (Grant No. XN129).

Self-Encoded Spread Spectrum Modulation for Robust Anti-Jamming Communication

DTIC Science & Technology

2009-06-30

experience in both theoretical and experimental aspects of RF and optical communications, multi-user CDMA systems, transmitter precoding and code...the performance of DS - and FH-SESS modulation in the presence of worst-case jamming, develop innovative SESS schemes that further exploit time and...Determine BER and AJ performance of the feedback and iterative detectors in DS -SESS under pulsed-noise and multi-tone jamming • Task 2: Develop a scheme

Value based pricing, research and development, and patient access schemes. Will the United Kingdom get it right or wrong?

PubMed Central

Towse, Adrian

2010-01-01

The National Health Service (NHS) should reward innovation it values. This will enable the NHS and the United Kingdom (UK) economy to benefit and impact positively on the Research and Development (R&D) decision making of companies. The National Institute for Health and Clinical Excellence (NICE) currently seeks to do this on behalf of the NHS. Yet the Office of Fair Trading proposals for Value Based Pricing add price setting powers – initially for the Department of Health (DH) and then for NICE. This introduces an additional substantial uncertainty that will impact on R&D and, conditional on R&D proceeding, on launch (or not) in the UK. Instead of adding to uncertainty the institutional arrangements for assessing value should seek to be predictable and science based, building on NICE's current arrangements. The real challenge is to increase understanding of the underlying cost-effectiveness of the technology itself by collecting evidence alongside use. The 2009 Pharmaceutical Price Regulation Scheme sought to help do this with Flexible Pricing (FP) and Patient Access Schemes (PASs). The PASs to date have increased access to medicines, but no schemes proposed to date have yet helped to tackle outcomes uncertainty. The 2010 Innovation Pass can also be seen as a form of ‘coverage with evidence development.’ The NHS is understandably concerned about the costs of running such evidence collection schemes. Enabling the NHS to deliver on such schemes will impact favourably on R&D decisions. Increasing the uncertainty in the UK NHS market through government price setting will reduce incentives for R&D and for early UK launch. PMID:20716236

Value based pricing, research and development, and patient access schemes. Will the United Kingdom get it right or wrong?

PubMed

Towse, Adrian

2010-09-01

The National Health Service (NHS) should reward innovation it values. This will enable the NHS and the United Kingdom (UK) economy to benefit and impact positively on the Research and Development (R&D) decision making of companies. The National Institute for Health and Clinical Excellence (NICE) currently seeks to do this on behalf of the NHS. Yet the Office of Fair Trading proposals for Value Based Pricing add price setting powers--initially for the Department of Health (DH) and then for NICE. This introduces an additional substantial uncertainty that will impact on R&D and, conditional on R&D proceeding, on launch (or not) in the UK. Instead of adding to uncertainty the institutional arrangements for assessing value should seek to be predictable and science based, building on NICE's current arrangements. The real challenge is to increase understanding of the underlying cost-effectiveness of the technology itself by collecting evidence alongside use. The 2009 Pharmaceutical Price Regulation Scheme sought to help do this with Flexible Pricing (FP) and Patient Access Schemes (PASs). The PASs to date have increased access to medicines, but no schemes proposed to date have yet helped to tackle outcomes uncertainty. The 2010 Innovation Pass can also be seen as a form of 'coverage with evidence development.' The NHS is understandably concerned about the costs of running such evidence collection schemes. Enabling the NHS to deliver on such schemes will impact favourably on R&D decisions. Increasing the uncertainty in the UK NHS market through government price setting will reduce incentives for R&D and for early UK launch.

Lidar Luminance Quantizer

NASA Technical Reports Server (NTRS)

Quilligan, Gerard; DeMonthier, Jeffrey; Suarez, George

2011-01-01

This innovation addresses challenges in lidar imaging, particularly with the detection scheme and the shapes of the detected signals. Ideally, the echoed pulse widths should be extremely narrow to resolve fine detail at high event rates. However, narrow pulses require wideband detection circuitry with increased power dissipation to minimize thermal noise. Filtering is also required to shape each received signal into a form suitable for processing by a constant fraction discriminator (CFD) followed by a time-to-digital converter (TDC). As the intervals between the echoes decrease, the finite bandwidth of the shaping circuits blends the pulses into an analog signal (luminance) with multiple modes, reducing the ability of the CFD to discriminate individual events

High-efficiency space-based software radio architectures & algorithms (a minimum size, weight, and power TeraOps processor)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunham, Mark Edward; Baker, Zachary K; Stettler, Matthew W

2009-01-01

Los Alamos has recently completed the latest in a series of Reconfigurable Software Radios, which incorporates several key innovations in both hardware design and algorithms. Due to our focus on satellite applications, each design must extract the best size, weight, and power performance possible from the ensemble of Commodity Off-the-Shelf (COTS) parts available at the time of design. In this case we have achieved 1 TeraOps/second signal processing on a 1920 Megabit/second datastream, while using only 53 Watts mains power, 5.5 kg, and 3 liters. This processing capability enables very advanced algorithms such as our wideband RF compression scheme tomore » operate remotely, allowing network bandwidth constrained applications to deliver previously unattainable performance.« less

Reviewing Landmark Nitrogen Cap and Trade Legislation in New Zealand's Taupo Catchment: What Have We Learned after 5+ Years?

NASA Astrophysics Data System (ADS)

Baisden, W. T.; Hamilton, D. P.

2014-12-01

In 2007, the first cap and trade legislation for a catchment nitrogen (N) budget was enacted to protect water quality in New Zealand's iconic Lake Taupo. The clarity of the 616 km² N-limited oligotrophic lake was declining due to human-induced increases in N losses from the 3,487 km² catchment. Focus was placed on reversing increases in N inputs from agriculture, and to a lesser degree sewerage sources. The legislation imposed a cap equal to 20% reduction in the N inputs to the lake, and enabled trading. The landmark legislation could have failed during appeal. Sources of disagreement included the N budgeting model and grand-parenting method that benchmarked the N leaching of individual farms. The N leaching rates for key land uses were also a major battleground, with strong effects on the viability of trading and relative value of enterprises. Sufficient science was applied to resolve the substantive issues in the appeal by 2008. Crucially, the decision recognized that N inputs to the "N cascade" mattered more than leaching evidence including land-use legacies. Other catchment cap-and-trade schemes followed. Rotorua Lakes had already capped inputs and established a ~33% N input reduction target after acceptance of a trading scheme compatible with groundwater lag times. In the Upper Manawatu catchment, a cap-and-trade scheme now governs river N loads in a more typical farming region, with an innovative allocation scheme based on the natural capital of soils. Collectively, these schemes have succeeded in imposing a cap, and signaling the intention of reductions over time. I conclude with common themes in the successes, and examine the role of science in the success and ongoing implementation. Central to success has been the role of science in framing N budgets at farm and catchment scales. Long-term data has been invaluable, despite the need to correct biases. Cap-and-trade policies alter future science needs toward reducing uncertainty in overall budgets, the ability to measure success or failure in innovative source reductions at a management scale, and defining quantitative measures of aquatic health. Broadly, the schemes have enabled a culture of innovation, in farming and research. For example, recent evidence suggests it may be possible to flip the Rotorua Lakes into a P limitation regime through alum dosing.

Open data models for smart health interconnected applications: the example of openEHR.

PubMed

Demski, Hans; Garde, Sebastian; Hildebrand, Claudia

2016-10-22

Smart Health is known as a concept that enhances networking, intelligent data processing and combining patient data with other parameters. Open data models can play an important role in creating a framework for providing interoperable data services that support the development of innovative Smart Health applications profiting from data fusion and sharing. This article describes a model-driven engineering approach based on standardized clinical information models and explores its application for the development of interoperable electronic health record systems. The following possible model-driven procedures were considered: provision of data schemes for data exchange, automated generation of artefacts for application development and native platforms that directly execute the models. The applicability of the approach in practice was examined using the openEHR framework as an example. A comprehensive infrastructure for model-driven engineering of electronic health records is presented using the example of the openEHR framework. It is shown that data schema definitions to be used in common practice software development processes can be derived from domain models. The capabilities for automatic creation of implementation artefacts (e.g., data entry forms) are demonstrated. Complementary programming libraries and frameworks that foster the use of open data models are introduced. Several compatible health data platforms are listed. They provide standard based interfaces for interconnecting with further applications. Open data models help build a framework for interoperable data services that support the development of innovative Smart Health applications. Related tools for model-driven application development foster semantic interoperability and interconnected innovative applications.

Innovative FEL schemes using variable-gap undulators

NASA Astrophysics Data System (ADS)

Schneidmiller, E. A.; Yurkov, M. V.

2017-06-01

We discuss theoretical background and experimental verification of advanced schemes for X-ray FELs using variable gap undulators (harmonic lasing self-seeded FEL, reverse taper etc.) Harmonic lasing in XFELs is an opportunity to extend operating range of existing and planned X-ray FEL user facilities. Contrary to nonlinear harmonic generation, harmonic lasing can provide much more intense, stable, and narrow-band FEL beam which is easier to handle due to the suppressed fundamental. Another interesting application of harmonic lasing is Harmonic Lasing Self-Seeded (HLSS) FEL that allows to improve longitudinal coherence and spectral power of a SASE FEL. Recently this concept was successfully tested at the soft X-ray FEL user facility FLASH in the wavelength range between 4.5 nm and 15 nm. That was also the first experimental demonstration of harmonic lasing in a high-gain FEL and at a short wavelength (before it worked only in infrared FEL oscillators). Another innovative scheme that was tested at FLASH2 is the reverse tapering that can be used to produce circularly polarized radiation from a dedicated afterburner with strongly suppressed linearly polarized radiation from the main undulator. This scheme can also be used for an efficient background-free production of harmonics in an afterburner. Experiments on the frequency doubling that allowed to reach the shortest wavelength at FLASH as well as on post-saturation tapering to produce a record intencity in XUV regime are also discussed.

Changing the Translational Research Landscape: A Review of the Impacts of Biomedical Research Units in England.

PubMed

Marjanovic, Sonja; Soper, Bryony; Ismail, Sharif; Reding, Anais; Ling, Tom

2012-01-01

This article describes a review of the Biomedical Research Units (BRU) scheme, undertaken for the Department of Health. This review was a perceptions audit of senior executives involved in the scheme, and explored what impact they felt the scheme is having on the translational research landscape. More specifically, we investigated whether and how institutional relationships between NHS and academic partners, industry and other health research system players are changing because of the scheme; how the scheme is helping build critical mass in specific priority disease areas; and the effects of any changes on efforts to deliver the broader goals set out in Best Research for Best Health. The views presented are those of study informants only. The information obtained through our interviews suggests that the BRU scheme is significantly helping shape the health research system to pursue translational research and innovation, with the clear goal of realising patient benefit. The BRUs are already contributing to observable changes in institutional relationships between the NHS and academic partners: trusts and medical schools are collaborating more closely than in the past, have signed up to the same vision of translational research from bench to bedside, and are managing and governing targeted research resources more professionally and transparently than in the past. There is also a stronger emphasis on engaging industry and more strategic thinking about strengthening regional and national collaboration with other hospital trusts, PCTs, research organisations, networks and development agencies. The scheme is also transforming capacity building in the health research system. This includes (i) developing and modernising facilities and equipment for translation; (ii) building a critical mass of human resources through recruitment and training, as well as improving retention of existing expertise; and (iii) helping ensure a steady flow of funds needed to sustain research activity and accelerate movement through the innovation pipeline. A number of centres are also trying to recreate the BRU model in new disease areas, with their own resources.

Suboptimal distributed control and estimation: application to a four coupled tanks system

NASA Astrophysics Data System (ADS)

Orihuela, Luis; Millán, Pablo; Vivas, Carlos; Rubio, Francisco R.

2016-06-01

The paper proposes an innovative estimation and control scheme that enables the distributed monitoring and control of large-scale processes. The proposed approach considers a discrete linear time-invariant process controlled by a network of agents that may both collect information about the evolution of the plant and apply control actions to drive its behaviour. The problem makes full sense when local observability/controllability is not assumed and the communication between agents can be exploited to reach system-wide goals. Additionally, to reduce agents bandwidth requirements and power consumption, an event-based communication policy is studied. The design procedure guarantees system stability, allowing the designer to trade-off performance, control effort and communication requirements. The obtained controllers and observers are implemented in a fully distributed fashion. To illustrate the performance of the proposed technique, experimental results on a quadruple-tank process are provided.

Positron-Electron Annihilation Process in (2,2)-Difluoropropane Molecule

NASA Astrophysics Data System (ADS)

Liu, Yang; Ma, Xiao-Guang; Zhu, Ying-Hao

2016-04-01

The positron-electron annihilation process in (2,2)-difluoropropane molecule and the corresponding gamma-ray spectra are studied by quantum chemistry method. The positrophilic electrons in (2,2)-difluoropropane molecule are found for the first time. The theoretical predictions show that the outermost 2s electrons of fluoride atoms play an important role in positron-electron annihilation process of (2,2)-difiuoropropane. In the present scheme, the correlation coefficient between the theoretical gamma-ray spectra and the experiments can be 99%. The present study gives an alternative annihilation model for positron-electron pair in larger molecules. Supported by the National Natural Science Foundation of China under Grant No. 11347011 and the Natural Science Foundation Project of Shandong Province under Grant No. ZR2011AM010 and 2014 Technology Innovation Fund of Ludong University under Grant Nos. 1d151007 and ld15l016

Microinsurance: innovations in low-cost health insurance.

PubMed

Dror, David M; Radermacher, Ralf; Khadilkar, Shrikant B; Schout, Petra; Hay, François-Xavier; Singh, Arbind; Koren, Ruth

2009-01-01

Microinsurance--low-cost health insurance based on a community, cooperative, or mutual and self-help arrangements-can provide financial protection for poor households and improve access to health care. However, low benefit caps and a low share of premiums paid as benefits--both designed to keep these arrangements in business--perversely limited these schemes' ability to extend coverage, offer financial protection, and retain members. We studied three schemes in India, two of which are member-operated and one a commercial scheme, using household surveys of insured and uninsured households and interviews with managers. All three enrolled poor households and raised their use of hospital services, as intended. Financial exposure was greatest, and protection was least, in the commercial scheme, which imposed the lowest caps on benefits and where income was the lowest.

Dual-beam laser autofocusing system based on liquid lens

NASA Astrophysics Data System (ADS)

Zhang, Fumin; Yao, Yannan; Qu, Xinghua; Zhang, Tong; Pei, Bing

2017-02-01

A dual-beam laser autofocusing system is designed in this paper. The autofocusing system is based on a liquid lens with less moving parts and fast response time, which makes the system simple, reliable, compact and fast. A novel scheme ;Time-sharing focus, fast conversion; is innovatively proposed. The scheme effectively solves the problem that the guiding laser and the working laser cannot focus at the same target point because of the existence of chromatic aberration. This scheme not only makes both guiding laser and working laser achieve optimal focusing in guiding stage and working stage respectively, but also greatly reduces the system complexity and simplifies the focusing process as well as makes autofocusing time of the working laser reduce to about 10 ms. In the distance range of 1 m to 30 m, the autofocusing spot size is kept under 4.3 mm at 30 m and just 0.18 mm at 1 m. The spot size is much less influenced by the target distance compared with the collimated laser with a micro divergence angle for its self-adaptivity. The dual-beam laser autofocusing system based on liquid lens is fully automatic, compact and efficient. It is fully meet the need of dynamicity and adaptivity and it will play an important role in a number of long-range control applications.

Tracking multiple particles in fluorescence time-lapse microscopy images via probabilistic data association.

PubMed

Godinez, William J; Rohr, Karl

2015-02-01

Tracking subcellular structures as well as viral structures displayed as 'particles' in fluorescence microscopy images yields quantitative information on the underlying dynamical processes. We have developed an approach for tracking multiple fluorescent particles based on probabilistic data association. The approach combines a localization scheme that uses a bottom-up strategy based on the spot-enhancing filter as well as a top-down strategy based on an ellipsoidal sampling scheme that uses the Gaussian probability distributions computed by a Kalman filter. The localization scheme yields multiple measurements that are incorporated into the Kalman filter via a combined innovation, where the association probabilities are interpreted as weights calculated using an image likelihood. To track objects in close proximity, we compute the support of each image position relative to the neighboring objects of a tracked object and use this support to recalculate the weights. To cope with multiple motion models, we integrated the interacting multiple model algorithm. The approach has been successfully applied to synthetic 2-D and 3-D images as well as to real 2-D and 3-D microscopy images, and the performance has been quantified. In addition, the approach was successfully applied to the 2-D and 3-D image data of the recent Particle Tracking Challenge at the IEEE International Symposium on Biomedical Imaging (ISBI) 2012.

SIMULATING ATMOSPHERIC EXPOSURE USING AN INNOVATIVE METEOROLOGICAL SAMPLING SCHEME

EPA Science Inventory

Multimedia Risk assessments require the temporal integration of atmospheric concentration and deposition estimates with other media modules. However, providing an extended time series of estimates is computationally expensive. An alternative approach is to substitute long-ter...

Innovative hyperchaotic encryption algorithm for compressed video

NASA Astrophysics Data System (ADS)

Yuan, Chun; Zhong, Yuzhuo; Yang, Shiqiang

2002-12-01

It is accepted that stream cryptosystem can achieve good real-time performance and flexibility which implements encryption by selecting few parts of the block data and header information of the compressed video stream. Chaotic random number generator, for example Logistics Map, is a comparatively promising substitute, but it is easily attacked by nonlinear dynamic forecasting and geometric information extracting. In this paper, we present a hyperchaotic cryptography scheme to encrypt the compressed video, which integrates Logistics Map with Z(232 - 1) field linear congruential algorithm to strengthen the security of the mono-chaotic cryptography, meanwhile, the real-time performance and flexibility of the chaotic sequence cryptography are maintained. It also integrates with the dissymmetrical public-key cryptography and implements encryption and identity authentification on control parameters at initialization phase. In accord with the importance of data in compressed video stream, encryption is performed in layered scheme. In the innovative hyperchaotic cryptography, the value and the updating frequency of control parameters can be changed online to satisfy the requirement of the network quality, processor capability and security requirement. The innovative hyperchaotic cryprography proves robust security by cryptoanalysis, shows good real-time performance and flexible implement capability through the arithmetic evaluating and test.

Simulation of thin slot spirals and dual circular patch antennas using the finite element method with mixed elements

NASA Technical Reports Server (NTRS)

Gong, Jian; Volakis, John L.; Nurnberger, Michael W.

1995-01-01

This semi-annual report describes progress up to mid-January 1995. The report contains five sections all dealing with the modeling of spiral and patch antennas recessed in metallic platforms. Of significance is the development of decomposition schemes which separate the different regions of the antenna volume. Substantial effort was devoted to improving the feed model in the context of the finite element method (FEM). Finally, an innovative scheme for truncating finite element meshes is presented.

Innovative resettlement schemes planned for the Numata Dam project

NASA Astrophysics Data System (ADS)

Nakayama, Mikiyasu

2003-10-01

The Numata Dam, planned for the Tone River basin of Gunma Prefecture, was the largest dam construction project ever considered in Japan. This dam construction project, however, did not materialize. The proposal for the Numata Dam was first launched in 1959, at a time when the Tokyo Metropolitan area was mushrooming, both in population and industrial activity. The Numata Dam was supposed to be a prioritized dam construction project to alleviate the then anticipated water shortage in the Tokyo Metropolitan area. The Numata Dam plan experienced fierce opposition from those who would have been obliged to resettle, whereas those in Tokyo and the surrounding metropolitan area welcomed the plan. The major concern of the planned Numata Dam was the number of resettlers, which was then estimated to be around 3000 families. The resettlement plan developed for the Numata Dam included some innovative concepts, which may be applicable even today, for dam construction projects in the developing world. The plan included such ideas as (a) having resettlers share existing farmland with the present owners provided improvements were made to increase productivity, (b) paying rent to resettlers, and (c) establishing the Tone River Development Agency. After more than a decade of debate, both at national and local levels, the Numata Dam project was finally discarded through a decision of the Prime Minister in 1972. The resettlement schemes elaborated for the Numata Dam still appear to be innovative. Such schemes may be applied to projects in the developing world, in particular, in nations that are about to take off with economic development. Copyright

[Possibility of 3D Printing in Ophthalmology - First Experiences by Stereotactic Radiosurgery Planning Scheme of Intraocular Tumor].

PubMed

Furdová, A; Furdová, Ad; Thurzo, A; Šramka, M; Chorvát, M; Králik, G

Nowadays 3D printing allows us to create physical objects on the basis of digital data. Thanks to its rapid development the use enormously increased in medicine too. Its creations facilitate surgical planning processes, education and research in context of organ transplantation, individualization prostheses, breast forms, and others.Our article describes the wide range of applied 3D printing technology possibilities in ophthalmology. It is focusing on innovative implementation of eye tumors treatment planning in stereotactic radiosurgery irradiation.We analyze our first experience with 3D printing model of the eye in intraocular tumor planning stereotactic radiosurgery. 3D printing, model, Fused Deposition Modelling, stereotactic radiosurgery, prostheses, intraocular tumor.

Dual-modality brain PET-CT image segmentation based on adaptive use of functional and anatomical information.

PubMed

Xia, Yong; Eberl, Stefan; Wen, Lingfeng; Fulham, Michael; Feng, David Dagan

2012-01-01

Dual medical imaging modalities, such as PET-CT, are now a routine component of clinical practice. Medical image segmentation methods, however, have generally only been applied to single modality images. In this paper, we propose the dual-modality image segmentation model to segment brain PET-CT images into gray matter, white matter and cerebrospinal fluid. This model converts PET-CT image segmentation into an optimization process controlled simultaneously by PET and CT voxel values and spatial constraints. It is innovative in the creation and application of the modality discriminatory power (MDP) coefficient as a weighting scheme to adaptively combine the functional (PET) and anatomical (CT) information on a voxel-by-voxel basis. Our approach relies upon allowing the modality with higher discriminatory power to play a more important role in the segmentation process. We compared the proposed approach to three other image segmentation strategies, including PET-only based segmentation, combination of the results of independent PET image segmentation and CT image segmentation, and simultaneous segmentation of joint PET and CT images without an adaptive weighting scheme. Our results in 21 clinical studies showed that our approach provides the most accurate and reliable segmentation for brain PET-CT images. Copyright © 2011 Elsevier Ltd. All rights reserved.

Can Children Enhance Their Family's Health Knowledge? An Infectious Disease Prevention Program

PubMed Central

Sedighi, Iraj; Nouri, Shahla; Sadrosadat, Taravat; Nemati, Reza; Shahbazi, Mojgan

2012-01-01

Objective The purpose of this study is to propose an innovative method of knowledge transfer that aims to improve health literacy about pediatric infectious diseases prevention in families. Children have an appreciable role in this scheme. Methods This study is a before and after trial that has been conducted in Hamedan in 2009. After changing seven infectious disease topics into childish poems, we selected five kindergartens randomly and taught these poetries to the children. Teaching process held after a pretest containing 24 questions that examined 103 of parents about mentioned topics. The same post-test was given after 4 months of teaching process. Findings The mean of correct answers to the pretest was 59.22% comparable with 81.00% for post-test (P<0.00). Gender and knowledge degree could not change the results significantly. Assuming one's correct answers to the questions as his/her Knowledge Mark, the mean of this variable increased to 5.32 by this method. Conclusion This cost-effective and joyful method had successful results in promoting health knowledge. Children are able to play an active role in family's health situation. Learning within family atmosphere without any obligations makes our scheme a solution for paving the knowledge transferring way. PMID:23430134

Comparative Analysis Of River Conservation In The United States And South Africa

EPA Science Inventory

Both the United States and South Africa are recognized for their strong and innovative approaches to the conservation of river ecosystems. These national programs possess similar driving legislation and ecoregional classification schemes supported by comprehensive monitoring prog...

Connecting Neurons to a Mobile Robot: An In Vitro Bidirectional Neural Interface

PubMed Central

Novellino, A.; D'Angelo, P.; Cozzi, L.; Chiappalone, M.; Sanguineti, V.; Martinoia, S.

2007-01-01

One of the key properties of intelligent behaviors is the capability to learn and adapt to changing environmental conditions. These features are the result of the continuous and intense interaction of the brain with the external world, mediated by the body. For this reason “embodiment” represents an innovative and very suitable experimental paradigm when studying the neural processes underlying learning new behaviors and adapting to unpredicted situations. To this purpose, we developed a novel bidirectional neural interface. We interconnected in vitro neurons, extracted from rat embryos and plated on a microelectrode array (MEA), to external devices, thus allowing real-time closed-loop interaction. The novelty of this experimental approach entails the necessity to explore different computational schemes and experimental hypotheses. In this paper, we present an open, scalable architecture, which allows fast prototyping of different modules and where coding and decoding schemes and different experimental configurations can be tested. This hybrid system can be used for studying the computational properties and information coding in biological neuronal networks with far-reaching implications for the future development of advanced neuroprostheses. PMID:18350128

Implications of non-sustainable agricultural water policies for the water-food nexus in large-scale irrigation systems: A remote sensing approach

NASA Astrophysics Data System (ADS)

Al Zayed, Islam Sabry; Elagib, Nadir Ahmed

2017-12-01

This study proposes a novel monitoring tool based on Satellite Remote Sensing (SRS) data to examine the status of water distribution and Water Use Efficiency (WUE) under changing water policies in large-scale and complex irrigation schemes. The aim is to improve our understanding of the water-food nexus in such schemes. With a special reference to the Gezira Irrigation Scheme (GeIS) in Sudan during the period 2000-2014, the tool devised herein is well suited for cases where validation data are absent. First, it introduces an index, referred to as the Crop Water Consumption Index (CWCI), to assess the efficiency of water policies. The index is defined as the ratio of actual evapotranspiration (ETa) over agricultural areas to total ETa for the whole scheme where ETa is estimated using the Simplified Surface Energy Balance model (SSEB). Second, the tool uses integrated Normalized Difference Vegetation Index (iNDVI), as a proxy for crop productivity, and ETa to assess the WUE. Third, the tool uses SSEB ETa and NDVI in an attempt to detect wastage of water. Four key results emerged from this research as follows: 1) the WUE has not improved despite the changing agricultural and water policies, 2) the seasonal ETa can be used to detect the drier areas of GeIS, i.e. areas with poor irrigation water supply, 3) the decreasing trends of CWCI, slope of iNDVI-ETa linear regression and iNDVI are indicative of inefficient utilization of irrigation water in the scheme, and 4) it is possible to use SSEB ETa and NDVI to identify channels with spillover problems and detect wastage of rainwater that is not used as a source for irrigation. In conclusion, the innovative tool developed herein has provided important information on the efficiency of a large-scale irrigation scheme to help rationalize laborious water management processes and increase productivity.

SIMULATING ATMOSPHERIC EXPOSURE IN A NATIONAL RISK ASSESSMENT USING AN INNOVATIVE METEOROLOGICAL SAMPLING SCHEME

EPA Science Inventory

Multimedia risk assessments require the temporal integration of atmospheric concentration and deposition with other media modules. However, providing an extended time series of estimates is computationally expensive. An alternative approach is to substitute long-term average a...

Innovation Process Design: A Change Management and Innovation Dimension Perspective

NASA Astrophysics Data System (ADS)

Peisl, Thomas; Reger, Veronika; Schmied, Juergen

The authors propose an innovative approach to the management of innovation integrating business, process, and maturity dimensions. Core element of the concept is the adaptation of ISO/IEC 15504 to the innovation process including 14 innovation drivers. Two managerial models are applied to conceptualize and visualize the respective innovation strategies, the Balanced Scorecard and a Barriers in Change Processes Model. An illustrative case study shows a practical implementation process.

Preconditioning the Helmholtz Equation for Rigid Ducts

NASA Technical Reports Server (NTRS)

Baumeister, Kenneth J.; Kreider, Kevin L.

1998-01-01

An innovative hyperbolic preconditioning technique is developed for the numerical solution of the Helmholtz equation which governs acoustic propagation in ducts. Two pseudo-time parameters are used to produce an explicit iterative finite difference scheme. This scheme eliminates the large matrix storage requirements normally associated with numerical solutions to the Helmholtz equation. The solution procedure is very fast when compared to other transient and steady methods. Optimization and an error analysis of the preconditioning factors are present. For validation, the method is applied to sound propagation in a 2D semi-infinite hard wall duct.

How health economic evaluation (HEE) contributes to decision-making in public health care: the case of Brazil.

PubMed

Elias, Flávia Tavares Silva; Araújo, Denizar Vianna

2014-01-01

The universal access to a health care system for the Brazilian population was established in 1990. Brazil is a country with no tradition in the production and use of health economic evaluation (HEE) to guide decision making in the public health system. It is only within the last two decades that HEEs using a microeconomic approach have appeared in the academic field. On a national level, HEE and Health Technology Assessment (HTA), in a wider sense, were first taken into account in 2003. Two policies deserve to be mentioned - (i) the regulation of medicines in the Brazilian market, and (ii) science, technology and innovation policy. The latter required the fostering of applied research to encourage the application of methods which employ systematic reviews and economic analyses of cost-effectiveness to guide the incorporation of technologies in the Brazilian health care system. The Ministry of Health has initiated the process of incorporating these new technologies on a federal level during the last ten years. In spite of the improvement of HEE methods at Brazilian universities and research institutes, these technologies have not yet reached the governmental bodies. In Brazil, the main challenge lies in the production, interpretation and application of HEE to all technologies within the access scheme(s), and there is limited capacity building. Setting priorities can be the solution for Brazil to be able to perform HEE for relevant technologies within the access scheme(s) while the universal coverage system struggles with a triple burden of disease. Copyright © 2014. Published by Elsevier GmbH.

Development and application of a new comprehensive image-based classification scheme for coastal and benthic environments along the southeast Florida continental shelf

NASA Astrophysics Data System (ADS)

Makowski, Christopher

The coastal (terrestrial) and benthic environments along the southeast Florida continental shelf show a unique biophysical succession of marine features from a highly urbanized, developed coastal region in the north (i.e. northern Miami-Dade County) to a protective marine sanctuary in the southeast (i.e. Florida Keys National Marine Sanctuary). However, the establishment of a standard bio-geomorphological classification scheme for this area of coastal and benthic environments is lacking. The purpose of this study was to test the hypothesis and answer the research question of whether new parameters of integrating geomorphological components with dominant biological covers could be developed and applied across multiple remote sensing platforms for an innovative way to identify, interpret, and classify diverse coastal and benthic environments along the southeast Florida continental shelf. An ordered manageable hierarchical classification scheme was developed to incorporate the categories of Physiographic Realm, Morphodynamic Zone, Geoform, Landform, Dominant Surface Sediment, and Dominant Biological Cover. Six different remote sensing platforms (i.e. five multi-spectral satellite image sensors and one high-resolution aerial orthoimagery) were acquired, delineated according to the new classification scheme, and compared to determine optimal formats for classifying the study area. Cognitive digital classification at a nominal scale of 1:6000 proved to be more accurate than autoclassification programs and therefore used to differentiate coastal marine environments based on spectral reflectance characteristics, such as color, tone, saturation, pattern, and texture of the seafloor topology. In addition, attribute tables were created in conjugation with interpretations to quantify and compare the spatial relationships between classificatory units. IKONOS-2 satellite imagery was determined to be the optimal platform for applying the hierarchical classification scheme. However, each remote sensing platform had beneficial properties depending on research goals, logistical restrictions, and financial support. This study concluded that a new hierarchical comprehensive classification scheme for identifying coastal marine environments along the southeast Florida continental shelf could be achieved by integrating geomorphological features with biological coverages. This newly developed scheme, which can be applied across multiple remote sensing platforms with GIS software, establishes an innovative classification protocol to be used in future research studies.

SU-E-T-58: A Novel Monte Carlo Photon Transport Simulation Scheme and Its Application in Cone Beam CT Projection Simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Y; Southern Medical University, Guangzhou; Tian, Z

Purpose: Monte Carlo (MC) simulation is an important tool to solve radiotherapy and medical imaging problems. Low computational efficiency hinders its wide applications. Conventionally, MC is performed in a particle-by -particle fashion. The lack of control on particle trajectory is a main cause of low efficiency in some applications. Take cone beam CT (CBCT) projection simulation as an example, significant amount of computations were wasted on transporting photons that do not reach the detector. To solve this problem, we propose an innovative MC simulation scheme with a path-by-path sampling method. Methods: Consider a photon path starting at the x-ray source.more » After going through a set of interactions, it ends at the detector. In the proposed scheme, we sampled an entire photon path each time. Metropolis-Hasting algorithm was employed to accept/reject a sampled path based on a calculated acceptance probability, in order to maintain correct relative probabilities among different paths, which are governed by photon transport physics. We developed a package gMMC on GPU with this new scheme implemented. The performance of gMMC was tested in a sample problem of CBCT projection simulation for a homogeneous object. The results were compared to those obtained using gMCDRR, a GPU-based MC tool with the conventional particle-by-particle simulation scheme. Results: Calculated scattered photon signals in gMMC agreed with those from gMCDRR with a relative difference of 3%. It took 3.1 hr. for gMCDRR to simulate 7.8e11 photons and 246.5 sec for gMMC to simulate 1.4e10 paths. Under this setting, both results attained the same ∼2% statistical uncertainty. Hence, a speed-up factor of ∼45.3 was achieved by this new path-by-path simulation scheme, where all the computations were spent on those photons contributing to the detector signal. Conclusion: We innovatively proposed a novel path-by-path simulation scheme that enabled a significant efficiency enhancement for MC particle transport simulations.« less

Distortion correction of echo planar images applying the concept of finite rate of innovation to point spread function mapping (FRIP).

PubMed

Nunes, Rita G; Hajnal, Joseph V

2018-06-01

Point spread function (PSF) mapping enables estimating the displacement fields required for distortion correction of echo planar images. Recently, a highly accelerated approach was introduced for estimating displacements from the phase slope of under-sampled PSF mapping data. Sampling schemes with varying spacing were proposed requiring stepwise phase unwrapping. To avoid unwrapping errors, an alternative approach applying the concept of finite rate of innovation to PSF mapping (FRIP) is introduced, using a pattern search strategy to locate the PSF peak, and the two methods are compared. Fully sampled PSF data was acquired in six subjects at 3.0 T, and distortion maps were estimated after retrospective under-sampling. The two methods were compared for both previously published and newly optimized sampling patterns. Prospectively under-sampled data were also acquired. Shift maps were estimated and deviations relative to the fully sampled reference map were calculated. The best performance was achieved when using FRIP with a previously proposed sampling scheme. The two methods were comparable for the remaining schemes. The displacement field errors tended to be lower as the number of samples or their spacing increased. A robust method for estimating the position of the PSF peak has been introduced.

R & D on Beam Injection and Bunching Schemes in the Fermilab Booster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhat, C. M.

2016-01-01

Fermilab is committed to upgrade its accelerator complex to support HEP experiments at the intensity frontier. The ongoing Proton Improvement Plan (PIP) enables us to reach 700 kW beam power on the NuMI neutrino targets. By the end of the next decade, the current 400 MeV normal conducting LINAC will be replaced by an 800 MeV superconducting LINAC (PIP-II) with an increased beam power >50% of the PIP design goal. Both in PIP and PIP-II era, the existing Booster is going to play a very significant role, at least for next two decades. In the meanwhile, we have recently developedmore » an innovative beam injection and bunching scheme for the Booster called "early injection scheme" that continues to use the existing 400 MeV LINAC and implemented into operation. This scheme has the potential to increase the Booster beam intensity by >40% from the PIP design goal. Some benefits from the scheme have already been seen. In this paper, I will describe the basic principle of the scheme, results from recent beam experiments, our experience with the new scheme in operation, current status, issues and future plans. This scheme fits well with the current and future intensity upgrade programs at Fermilab.« less

Factors affecting adoption, implementation fidelity, and sustainability of the Redesigned Community Health Fund in Tanzania: a mixed methods protocol for process evaluation in the Dodoma region

PubMed Central

Kalolo, Albino; Radermacher, Ralf; Stoermer, Manfred; Meshack, Menoris; De Allegri, Manuela

2015-01-01

Background Despite the implementation of various initiatives to address low enrollment in voluntary micro health insurance (MHI) schemes in sub-Saharan Africa, the problem of low enrollment remains unresolved. The lack of process evaluations of such interventions makes it difficult to ascertain whether their poor results are because of design failures or implementation weaknesses. Objective In this paper, we describe a process evaluation protocol aimed at opening the ‘black box’ to evaluate the implementation processes of the Redesigned Community Health Fund (CHF) program in the Dodoma region of Tanzania. Design The study employs a cross-sectional mixed methods design and is being carried out 3 years after the launch of the Redesigned CHF program. The study is grounded in a conceptual framework which rests on the Diffusion of Innovation Theory and the Implementation Fidelity Framework. The study utilizes a mixture of quantitative and qualitative data collection tools (questionnaires, focus group discussions, in-depth interviews, and document review), and aligns the evaluation to the Theory of Intervention developed by our team. Quantitative data will be used to measure program adoption, implementation fidelity, and their moderating factors. Qualitative data will be used to explore the responses of stakeholders to the intervention, contextual factors, and moderators of adoption, implementation fidelity, and sustainability. Discussion This protocol describes a systematic process evaluation in relation to the implementation of a reformed MHI. We trust that the theoretical approaches and methodologies described in our protocol may be useful to inform the design of future process evaluations focused on the assessment of complex interventions, such as MHI schemes. PMID:26679408

A Hybrid Optimization Framework with POD-based Order Reduction and Design-Space Evolution Scheme

NASA Astrophysics Data System (ADS)

Ghoman, Satyajit S.

The main objective of this research is to develop an innovative multi-fidelity multi-disciplinary design, analysis and optimization suite that integrates certain solution generation codes and newly developed innovative tools to improve the overall optimization process. The research performed herein is divided into two parts: (1) the development of an MDAO framework by integration of variable fidelity physics-based computational codes, and (2) enhancements to such a framework by incorporating innovative features extending its robustness. The first part of this dissertation describes the development of a conceptual Multi-Fidelity Multi-Strategy and Multi-Disciplinary Design Optimization Environment (M3 DOE), in context of aircraft wing optimization. M 3 DOE provides the user a capability to optimize configurations with a choice of (i) the level of fidelity desired, (ii) the use of a single-step or multi-step optimization strategy, and (iii) combination of a series of structural and aerodynamic analyses. The modularity of M3 DOE allows it to be a part of other inclusive optimization frameworks. The M 3 DOE is demonstrated within the context of shape and sizing optimization of the wing of a Generic Business Jet aircraft. Two different optimization objectives, viz. dry weight minimization, and cruise range maximization are studied by conducting one low-fidelity and two high-fidelity optimization runs to demonstrate the application scope of M3 DOE. The second part of this dissertation describes the development of an innovative hybrid optimization framework that extends the robustness of M 3 DOE by employing a proper orthogonal decomposition-based design-space order reduction scheme combined with the evolutionary algorithm technique. The POD method of extracting dominant modes from an ensemble of candidate configurations is used for the design-space order reduction. The snapshot of candidate population is updated iteratively using evolutionary algorithm technique of fitness-driven retention. This strategy capitalizes on the advantages of evolutionary algorithm as well as POD-based reduced order modeling, while overcoming the shortcomings inherent with these techniques. When linked with M3 DOE, this strategy offers a computationally efficient methodology for problems with high level of complexity and a challenging design-space. This newly developed framework is demonstrated for its robustness on a nonconventional supersonic tailless air vehicle wing shape optimization problem.

A design of mathematical modelling for the mudharabah scheme in shariah insurance

NASA Astrophysics Data System (ADS)

Cahyandari, R.; Mayaningsih, D.; Sukono

2017-01-01

Indonesian Shariah Insurance Association (AASI) believes that 2014 is the year of Indonesian Shariah insurance, since its growth was above the conventional insurance. In December 2013, 43% growth was recorded for shariah insurance, while the conventional insurance was only hit 20%. This means that shariah insurance has tremendous potential to remain growing in the future. In addition, the growth can be predicted from the number of conventional insurance companies who open sharia division, along with the development of Islamic banking development which automatically demand the role of shariah insurance to protect assets and banking transactions. The development of shariah insurance should be accompanied by the development of premium fund management mechanism, in order to create innovation on shariah insurance products which beneficial for the society. The development of premium fund management model shows a positive progress through the emergence of Mudharabah, Wakala, Hybrid (Mudharabah-Wakala), and Wakala-Waqf. However, ‘model’ term that referred in this paper is regarded as an operational model in form of a scheme of management mechanism. Therefore, this paper will describe a mathematical modeling for premium fund management scheme, especially for Mudharabah concept. Mathematical modeling is required for an analysis process that can be used to predict risks that could be faced by a company in the future, so that the company could take a precautionary policy to minimize those risks.

Innovation and The Welfare Effects of Public Drug Insurance*

PubMed Central

Lakdawalla, Darius; Sood, Neeraj

2010-01-01

Rewarding inventors with inefficient monopoly power has long been regarded as the price of encouraging innovation. Prescription drug insurance escapes that trade-off and achieves an elusive goal: lowering static deadweight loss, without reducing incentives for innovation. As a result of this feature, the public provision of drug insurance can be welfare-improving, even for risk-neutral and purely self-interested consumers. The design of insurers’ cost-sharing schedules can either reinforce or mitigate this result. Schedules that impose higher consumer cost-sharing requirements on more expensive drugs help ensure that insurance subsidies translate into higher utilization, rather than pure increases in manufacturer profits. Moreover, some degree of price-negotiation with manufacturers is likely to be welfare-improving, but the optimal degree depends on the size of such transactions costs, as well as the social cost of weakening innovation incentives by lowering innovator profits. These results have practical implications for the evaluation of public drug insurance programs like the US Medicaid and Medicare Part D programs, along with European insurance schemes. PMID:20454467

Controlled information destruction: the final frontier in preserving information security for every organisation

NASA Astrophysics Data System (ADS)

Curiac, Daniel-Ioan; Pachia, Mihai

2015-05-01

Information security represents the cornerstone of every data processing system that resides in an organisation's trusted network, implementing all necessary protocols, mechanisms and policies to be one step ahead of possible threats. Starting from the need to strengthen the set of security services, in this article we introduce a new and innovative process named controlled information destruction (CID) that is meant to secure sensitive data that are no longer needed for the organisation's future purposes but would be very damaging if revealed. The disposal of this type of data has to be controlled carefully in order to delete not only the information itself but also all its splinters spread throughout the network, thus denying any possibility of recovering the information after its alleged destruction. This process leads to a modified model of information assurance and also reconfigures the architecture of any information security management system. The scheme we envisioned relies on a reshaped information lifecycle, which reveals the impact of the CID procedure directly upon the information states.

[Innovative ET cover system and its hydrologic evaluation].

PubMed

Liu, Chuan-shun; Cai, Jun-xiong; Wang, Jing-zhai; Rong, Yu

2010-07-01

The evapotranspiration (ET) cover system,as an alternative cover system of landfill, has been used in many remediation projects since 2003. It is an inexpensive, practical,and easily maintained biological system, but is mainly favorable in arid and semiarid sites due to limited water-holding capacity of the single loam layer and limited transpiration of grass. To improve the effectiveness of percolation control, an innovative scheme of ET was suggested in this paper: (1) a clay liner was added under the single loam layer to increase the water-holding capacity; (2) combined vegetation consisting of shrub and grass was used to replace the grass cover. Hydrologic evaluation of conventional cover,ET cover and the innovative ET cover under the same condition was performed using the computer program HELP, which showed the performance of the innovative ET cover is obviously superior to that of ET cover and conventional cover.

Assistive Technologies and Issues Relating to Privacy, Ethics and Security

NASA Astrophysics Data System (ADS)

Martin, Suzanne; Bengtsson, Johan E.; Dröes, Rose-Marie

Emerging technologies provide the opportunity to develop innovative sustainable service models, capable of supporting adults with dementia at home. Devices range from simple stand-alone components that can generate a responsive alarm call to complex interoperable systems that even can be remotely controlled. From these complex systems the paradigm of the ubiquitous or ambient smart home has emerged, integrating technology, environmental design and traditional care provision. The service context is often complex, involving a variety of stakeholders and a range of interested agencies. Against this backdrop, as anecdotal evidence and government policies spawn further innovation it is critical that due consideration is given to the potential ethical ramifications at an individual, organisational and societal level. Well-grounded ethical thinking and proactive ethical responses to this innovation are required. Explicit policy and practice should therefore emerge which engenders confidence in existing supported living option schemes for adults with dementia and informs further innovation.

A new third order finite volume weighted essentially non-oscillatory scheme on tetrahedral meshes

NASA Astrophysics Data System (ADS)

Zhu, Jun; Qiu, Jianxian

2017-11-01

In this paper a third order finite volume weighted essentially non-oscillatory scheme is designed for solving hyperbolic conservation laws on tetrahedral meshes. Comparing with other finite volume WENO schemes designed on tetrahedral meshes, the crucial advantages of such new WENO scheme are its simplicity and compactness with the application of only six unequal size spatial stencils for reconstructing unequal degree polynomials in the WENO type spatial procedures, and easy choice of the positive linear weights without considering the topology of the meshes. The original innovation of such scheme is to use a quadratic polynomial defined on a big central spatial stencil for obtaining third order numerical approximation at any points inside the target tetrahedral cell in smooth region and switch to at least one of five linear polynomials defined on small biased/central spatial stencils for sustaining sharp shock transitions and keeping essentially non-oscillatory property simultaneously. By performing such new procedures in spatial reconstructions and adopting a third order TVD Runge-Kutta time discretization method for solving the ordinary differential equation (ODE), the new scheme's memory occupancy is decreased and the computing efficiency is increased. So it is suitable for large scale engineering requirements on tetrahedral meshes. Some numerical results are provided to illustrate the good performance of such scheme.

A novel hybrid approach with multidimensional-like effects for compressible flow computations

NASA Astrophysics Data System (ADS)

Kalita, Paragmoni; Dass, Anoop K.

2017-07-01

A multidimensional scheme achieves good resolution of strong and weak shocks irrespective of whether the discontinuities are aligned with or inclined to the grid. However, these schemes are computationally expensive. This paper achieves similar effects by hybridizing two schemes, namely, AUSM and DRLLF and coupling them through a novel shock switch that operates - unlike existing switches - on the gradient of the Mach number across the cell-interface. The schemes that are hybridized have contrasting properties. The AUSM scheme captures grid-aligned (and strong) shocks crisply but it is not so good for non-grid-aligned weaker shocks, whereas the DRLLF scheme achieves sharp resolution of non-grid-aligned weaker shocks, but is not as good for grid-aligned strong shocks. It is our experience that if conventional shock switches based on variables like density, pressure or Mach number are used to combine the schemes, the desired effect of crisp resolution of grid-aligned and non-grid-aligned discontinuities are not obtained. To circumvent this problem we design a shock switch based - for the first time - on the gradient of the cell-interface Mach number with very impressive results. Thus the strategy of hybridizing two carefully selected schemes together with the innovative design of the shock switch that couples them, affords a method that produces the effects of a multidimensional scheme with a lower computational cost. It is further seen that hybridization of the AUSM scheme with the recently developed DRLLFV scheme using the present shock switch gives another scheme that provides crisp resolution for both shocks and boundary layers. Merits of the scheme are established through a carefully selected set of numerical experiments.

The importance of basic factors in innovation processes and their effects on innovation capability of Malaysian-owned manufacturing companies

NASA Astrophysics Data System (ADS)

Suradi, Nur Riza Mohd; Omar, Aminuddin; Shahabuddin, Faridatulazna Ahmad

2015-02-01

Innovation is the core ingredient in the competitiveness of today's businesses. Any company that cannot innovate will be losing its competitiveness. While the study on innovation at conceptual level is widely available, there is still lack of deep understanding of how innovation factors impact each stage of the processes of innovation that happen in Malaysian companies. This process-factor approach and understanding may help the government focuses its assistance on relevant factors at relevant process according to the size of the company. This study examines how companies are affected by fundamental factors needed in innovation. Based on results of MYTIC Study 2012 on the level of Technological Innovation Capability (TIC) of Malaysian companies using the RDCB framework, the significance of each innovation factor in each innovation process is determined. This study shows that human resource factor gives more impact than other factors in most processes. Also, financial and human resource factors are likely dictated by the size of the company.

Sources of Information as Determinants of Product and Process Innovation.

PubMed

Gómez, Jaime; Salazar, Idana; Vargas, Pilar

2016-01-01

In this paper we use a panel of manufacturing firms in Spain to examine the extent to which they use internal and external sources of information (customers, suppliers, competitors, consultants and universities) to generate product and process innovation. Our results show that, although internal sources are influential, external sources of information are key to achieve innovation performance. These results are in line with the open innovation literature because they show that firms that are opening up their innovation process and that use different information sources have a greater capacity to generate innovations. We also find that the importance of external sources of information varies depending on the type of innovation (product or process) considered. To generate process innovation, firms mainly rely on suppliers while, to generate product innovation, the main contribution is from customers. The potential simultaneity between product and process innovation is also taken into consideration. We find that the generation of both types of innovation is not independent.

Sources of Information as Determinants of Product and Process Innovation

PubMed Central

2016-01-01

In this paper we use a panel of manufacturing firms in Spain to examine the extent to which they use internal and external sources of information (customers, suppliers, competitors, consultants and universities) to generate product and process innovation. Our results show that, although internal sources are influential, external sources of information are key to achieve innovation performance. These results are in line with the open innovation literature because they show that firms that are opening up their innovation process and that use different information sources have a greater capacity to generate innovations. We also find that the importance of external sources of information varies depending on the type of innovation (product or process) considered. To generate process innovation, firms mainly rely on suppliers while, to generate product innovation, the main contribution is from customers. The potential simultaneity between product and process innovation is also taken into consideration. We find that the generation of both types of innovation is not independent. PMID:27035456

A modified NARMAX model-based self-tuner with fault tolerance for unknown nonlinear stochastic hybrid systems with an input-output direct feed-through term.

PubMed

Tsai, Jason S-H; Hsu, Wen-Teng; Lin, Long-Guei; Guo, Shu-Mei; Tann, Joseph W

2014-01-01

A modified nonlinear autoregressive moving average with exogenous inputs (NARMAX) model-based state-space self-tuner with fault tolerance is proposed in this paper for the unknown nonlinear stochastic hybrid system with a direct transmission matrix from input to output. Through the off-line observer/Kalman filter identification method, one has a good initial guess of modified NARMAX model to reduce the on-line system identification process time. Then, based on the modified NARMAX-based system identification, a corresponding adaptive digital control scheme is presented for the unknown continuous-time nonlinear system, with an input-output direct transmission term, which also has measurement and system noises and inaccessible system states. Besides, an effective state space self-turner with fault tolerance scheme is presented for the unknown multivariable stochastic system. A quantitative criterion is suggested by comparing the innovation process error estimated by the Kalman filter estimation algorithm, so that a weighting matrix resetting technique by adjusting and resetting the covariance matrices of parameter estimate obtained by the Kalman filter estimation algorithm is utilized to achieve the parameter estimation for faulty system recovery. Consequently, the proposed method can effectively cope with partially abrupt and/or gradual system faults and input failures by the fault detection. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

A Novel Texture-Quantization-Based Reversible Multiple Watermarking Scheme Applied to Health Information System.

PubMed

Turuk, Mousami; Dhande, Ashwin

2018-04-01

The recent innovations in information and communication technologies have appreciably changed the panorama of health information system (HIS). These advances provide new means to process, handle, and share medical images and also augment the medical image security issues in terms of confidentiality, reliability, and integrity. Digital watermarking has emerged as new era that offers acceptable solutions to the security issues in HIS. Texture is a significant feature to detect the embedding sites in an image, which further leads to substantial improvement in the robustness. However, considering the perspective of digital watermarking, this feature has received meager attention in the reported literature. This paper exploits the texture property of an image and presents a novel hybrid texture-quantization-based approach for reversible multiple watermarking. The watermarked image quality has been accessed by peak signal to noise ratio (PSNR), structural similarity measure (SSIM), and universal image quality index (UIQI), and the obtained results are superior to the state-of-the-art methods. The algorithm has been evaluated on a variety of medical imaging modalities (CT, MRA, MRI, US) and robustness has been verified, considering various image processing attacks including JPEG compression. The proposed scheme offers additional security using repetitive embedding of BCH encoded watermarks and ADM encrypted ECG signal. Experimental results achieved a maximum of 22,616 bits hiding capacity with PSNR of 53.64 dB.

Regulation Scheme for Improved Innovation and Efficiency in Wireless Communications

DTIC Science & Technology

2009-03-01

that is reliable and available during all crises and emergencies. The last goal is the overall modernization of the FCC. “The FCC shall strive to...change. Qualcomm attempted to create a new video service to mobile subscribers. The service might have interfered with adjacent services. Qualcomm

Link Schools: An Evaluation of an Innovatory Scheme in Teacher Education.

ERIC Educational Resources Information Center

Boydell, Deanne

1990-01-01

The first year of an innovative British partnership between elementary schools, the school district, the teacher training institution, and teacher trainees is evaluated. The program integrates the needs of institutions, students, and professionals. Guiding principles relevant to the development of such partnerships and evaluation issues are…

ENVIRONMENTAL AND ECONOMIC IMPACT ANALYSIS OF MANURE DIGESTER BIOGAS-POWERED FUEL CELLS FOR THE AGRICULTURAL SECTOR

EPA Science Inventory

Through the ages, innovation and technology have consistently driven humanity. From his first discoveries to his latest and most cunning technological schemes, man has never failed to produce tailored ideas at the forefront of historically demanding times. This era is lik...

Technology's Impact on Faculty Life and Work.

ERIC Educational Resources Information Center

Baldwin, Roger G.

1998-01-01

Looks at the effects of advancing technology on academic life, using a simplified version of a scheme for examining diffusion of innovations. Attention is given to technology's impact on teaching, research and scholarship, and service and outreach functions, and on special challenges posed by technology, barriers to its use, and its implications…

Research to Assembly Scheme for Satellite Deck Based on Robot Flexibility Control Principle

NASA Astrophysics Data System (ADS)

Guo, Tao; Hu, Ruiqin; Xiao, Zhengyi; Zhao, Jingjing; Fang, Zhikai

2018-03-01

Deck assembly is critical quality control point in final satellite assembly process, and cable extrusion and structure collision problems in assembly process will affect development quality and progress of satellite directly. Aimed at problems existing in deck assembly process, assembly project scheme for satellite deck based on robot flexibility control principle is proposed in this paper. Scheme is introduced firstly; secondly, key technologies on end force perception and flexible docking control in the scheme are studied; then, implementation process of assembly scheme for satellite deck is described in detail; finally, actual application case of assembly scheme is given. Result shows that compared with traditional assembly scheme, assembly scheme for satellite deck based on robot flexibility control principle has obvious advantages in work efficiency, reliability and universality aspects etc.

31 CFR 592.301 - Controlled through the Kimberley Process Certification Scheme.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Process Certification Scheme. 592.301 Section 592.301 Money and Finance: Treasury Regulations Relating to... Certification Scheme. (a) Except as otherwise provided in paragraph (b) of this section, the term controlled through the Kimberley Process Certification Scheme refers to the following requirements that apply, as...

31 CFR 592.301 - Controlled through the Kimberley Process Certification Scheme.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Process Certification Scheme. 592.301 Section 592.301 Money and Finance: Treasury Regulations Relating to... Certification Scheme. (a) Except as otherwise provided in paragraph (b) of this section, the term controlled through the Kimberley Process Certification Scheme refers to the following requirements that apply, as...

31 CFR 592.301 - Controlled through the Kimberley Process Certification Scheme.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Process Certification Scheme. 592.301 Section 592.301 Money and Finance: Treasury Regulations Relating to... Certification Scheme. (a) Except as otherwise provided in paragraph (b) of this section, the term controlled through the Kimberley Process Certification Scheme refers to the following requirements that apply, as...

31 CFR 592.301 - Controlled through the Kimberley Process Certification Scheme.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Process Certification Scheme. 592.301 Section 592.301 Money and Finance: Treasury Regulations Relating to... Certification Scheme. (a) Except as otherwise provided in paragraph (b) of this section, the term controlled through the Kimberley Process Certification Scheme refers to the following requirements that apply, as...

31 CFR 592.301 - Controlled through the Kimberley Process Certification Scheme.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Process Certification Scheme. 592.301 Section 592.301 Money and Finance: Treasury Regulations Relating to... Certification Scheme. (a) Except as otherwise provided in paragraph (b) of this section, the term controlled through the Kimberley Process Certification Scheme refers to the following requirements that apply, as...

Funding the unfundable: mechanisms for managing uncertainty in decisions on the introduction of new and innovative technologies into healthcare systems.

PubMed

Stafinski, Tania; McCabe, Christopher J; Menon, Devidas

2010-01-01

As tensions between payers, responsible for ensuring prudent and principled use of scarce resources, and both providers and patients, who legitimately want access to technologies from which they could benefit, continue to mount, interest in approaches to managing the uncertainty surrounding the introduction of new health technologies has heightened. The purpose of this project was to compile an inventory of various types of 'access with evidence development' (AED) schemes, examining characteristics of the technologies to which they have been applied, the uncertainty they sought to address, the terms of arrangements of each scheme, and the policy outcomes. It also aimed to identify issues related to such schemes, including advantages and disadvantages from the perspectives of various stakeholder groups. A comprehensive search, review and appraisal of peer-reviewed and 'grey' literature were performed, followed by a facilitated workshop of academics and decision makers with expertise in AED schemes. Information was extracted and compiled in tabular form to identify patterns or trends. To enhance the validity of interpretations made, member checking was performed. Although the concept of AED is not new, evaluative data are sparse. Despite varying opinions on the 'right' answers to some of the questions raised, there appears to be consensus on a 'way forward'--development of methodological guidelines. All stakeholders seemed to share the view that AEDs offer the potential to facilitate patient access to promising new technologies and encourage innovation while ensuring effective use of scarce healthcare resources. There is no agreement on what constitutes 'sufficient evidence', and it depends on the specific uncertainty in question. There is agreement on the need for 'best practice' guidelines around the implementation and evaluation of AED schemes. This is the first attempt at a comprehensive analysis of methods that have been used to address uncertainty concerning a new drug or other technology. The analysis reveals that, although various approaches have been experimented with, many of them have not achieved the ostensible goal of the approach. This article outlines challenges related to AED schemes and issues that remain unresolved.

Combining image-processing and image compression schemes

NASA Technical Reports Server (NTRS)

Greenspan, H.; Lee, M.-C.

1995-01-01

An investigation into the combining of image-processing schemes, specifically an image enhancement scheme, with existing compression schemes is discussed. Results are presented on the pyramid coding scheme, the subband coding scheme, and progressive transmission. Encouraging results are demonstrated for the combination of image enhancement and pyramid image coding schemes, especially at low bit rates. Adding the enhancement scheme to progressive image transmission allows enhanced visual perception at low resolutions. In addition, further progressing of the transmitted images, such as edge detection schemes, can gain from the added image resolution via the enhancement.

Catalyzing healthcare transformation with digital health: Performance indicators and lessons learned from a Digital Health Innovation Group.

PubMed

Tseng, Jocelyn; Samagh, Sonia; Fraser, Donna; Landman, Adam B

2018-06-01

Despite considerable investment in digital health (DH) companies and a growing DH ecosystem, there are multiple challenges to testing and implementing innovative solutions. Health systems have recognized the potential of DH and have formed DH innovation centers. However, limited information is available on DH innovation center processes, best practices, or outcomes. This case report describes a DH innovation center process that can be replicated across health systems and defines and benchmarks process indicators to assess DH innovation center performance. The Brigham and Women's Hospital's Digital Health Innovation Group (DHIG) accelerates DH innovations from idea to pilot safely and efficiently using a structured process. Fifty-four DH innovations were accelerated by the DHIG process between July 2014 and December 2016. In order to measure effectiveness of the DHIG process, key process indicators were defined as 1) number of solutions that completed each DHIG phase and 2) length of time to complete each phase. Twenty-three DH innovations progressed to pilot stage and 13 innovations were terminated after barriers to pilot implementation were identified by the DHIG process. For 4 DH solutions that executed a pilot, the average time for innovations to proceed from DHIG intake to pilot initiation was 9 months. Overall, the DHIG is a reproducible process that addresses key roadblocks in DH innovation within health systems. To our knowledge, this is the first report to describe DH innovation process indicators and results within an academic health system. Therefore, there is no published data to compare our results with the results of other DH innovation centers. Standardized data collection and indicator reporting could allow benchmark comparisons across institutions. Additional opportunities exist for the validation of DH solution effectiveness and for translational support from pilot to implementation. These are critical steps to advance DH technologies and effectively leverage the DH ecosystem to transform healthcare. Copyright © 2017 Elsevier Inc. All rights reserved.

Market assessment of photovoltaic power systems for agricultural applications in the Philippines

NASA Technical Reports Server (NTRS)

Cabraal, R. A.; Delasanta, D.; Burrill, G.

1981-01-01

The market potential in the Philippines for stand alone photovoltaic (P/V) systems in agriculture was assessed. Applications include: irrigation, postharvest operation, food and fiber processing and storage, and livestock and fisheries operations. Power and energy use profiles for many applications as well as assessments of business, government and financial climate for P/V sales are described. Many characteristics of the Philippine agriculture and energy sector favorably influence the use of P/V systems. However, serious and significant barriers prevent achieving the technically feasible, cost competitive market for P/V systems in the agricultural sector. The reason for the small market is the limited availability capital for financing P/V systems. It is suggested that innovative financing schemes and promotional campaigns should be devised.

Concept of economic readiness levels assessment

NASA Astrophysics Data System (ADS)

Yuniaristanto, Sutopo, W.; Widiyanto, A.; Putri, A. S.

2017-11-01

This research aims to build a concept of Economic Readiness Level (ERL) assessment for incubation center. ERL concept is arranged by considering both market and business aspects. Every aspect is divided into four phases and each of them consists of some indicators. Analytic Hierarchy Process (AHP) is used to develop the ERL in calculating the weight of every single aspect and indicator. Interval scale between 0 and 4 is also applied in indicator assessment. In order to calculate ERL, score in every indicator and the weight of both the aspect and indicator are considered. ERL value is able to show in detail the innovative product readiness level from economic sight, market and business aspect. There are four levels in Economic Readiness Level scheme which are investigation, feasibility, planning and introduction.

Market assessment of photovoltaic power systems for agricultural applications in the Philippines

NASA Astrophysics Data System (ADS)

Cabraal, R. A.; Delasanta, D.; Burrill, G.

1981-04-01

The market potential in the Philippines for stand alone photovoltaic (P/V) systems in agriculture was assessed. Applications include: irrigation, postharvest operation, food and fiber processing and storage, and livestock and fisheries operations. Power and energy use profiles for many applications as well as assessments of business, government and financial climate for P/V sales are described. Many characteristics of the Philippine agriculture and energy sector favorably influence the use of P/V systems. However, serious and significant barriers prevent achieving the technically feasible, cost competitive market for P/V systems in the agricultural sector. The reason for the small market is the limited availability capital for financing P/V systems. It is suggested that innovative financing schemes and promotional campaigns should be devised.

A Novel High-Efficiency Rear-Contact Solar Cell with Bifacial Sensitivity

NASA Astrophysics Data System (ADS)

Hezel, R.

At present, wafer-based silicon solar cells have a share of more than 90% of the photovoltaic market. Despite rapid growth in the manufacturing volume, accompanied by a significant drop in the module selling price, the high costs currently associated with photovoltaic power generation are one of the most important obstacles to widespread global use of solar electricity. Up to a certain level, a higher production volume is a key driver in cost reduction. However, apart from a drastic reduction of the silicon wafer thickness in conjunction with improved light-trapping schemes, innovative processing sequences combining very high solar cell efficiencies with simple and cost-effective fabrication techniques are needed to become competitive with conventional energy sources and thus to move solar energy from niche to mainstream.

Process antecedents of challenging, under-cover and readily-adopted innovations.

PubMed

Adams, Richard; Tranfield, David; Denyer, David

2013-01-01

The purpose of the study is to test the utility of a taxonomy of innovation based on perceived characteristics in the context of healthcare by exploring the extent to which discrete innovation types could be distinguished from each other in terms of process antecedents. A qualitative approach was adopted to explore the process antecedents of nine exemplar cases of "challenging", "under-cover" and "readily-adopted" healthcare innovations. Data were collected by semi-structured interview and from secondary sources, and content analysed according to a theoretically informed framework of innovation process. Cluster analysis was applied to determine whether innovation types could be distinguished on the basis of process characteristics. The findings provide moderate support for the proposition that innovations differentiated on the basis of the way they are perceived by potential users exhibit different process characteristics. Innovations exhibiting characteristics previously believed negatively to impact adoption may be successfully adopted but by a different configuration of processes than by innovations exhibiting a different set of characteristics. The findings must be treated with caution because the sample consists of self-selected cases of successful innovation and is limited by sample size. Nevertheless, the study sheds new light on important process differences in healthcare innovation. The paper offers a heuristic device to aid clinicians and managers to better understand the relatively novel task of promoting and managing innovation in healthcare. The paper advances the argument that there is under-exploited opportunity for cross-disciplinary organisational learning for innovation management in the NHS. If efficiency and quality improvement targets are to be met through a strategy of encouraging innovation, it may be advantageous for clinicians and managers to reflect on what this study found mostly to be absent from the processes of the innovations studied, notably management commitment in the form of norms, resource allocation and top management support. This paper is based on original empirical work. It extends previous adoption related studies by applying a configurational approach to innovation attributes to offer new insights on healthcare innovation and highlight the importance of attention to process.

Rural Women, Money and Financial Service.

ERIC Educational Resources Information Center

Jiggins, Janice

1985-01-01

The author points out the multifaceted aspects of the problems associated with rural women's need for money and financial services and outlines innovative schemes in this area such as the bank for the landless in Bangladesh, a savings and loan cooperative for market women in Nicaragua, and a savings development movement in Zimbabwe. (CT)

Accumulate repeat accumulate codes

NASA Technical Reports Server (NTRS)

Abbasfar, A.; Divsalar, D.; Yao, K.

2004-01-01

In this paper we propose an innovative channel coding scheme called Accumulate Repeat Accumulate codes. This class of codes can be viewed as trubo-like codes, namely a double serial concatenation of a rate-1 accumulator as an outer code, a regular or irregular repetition as a middle code, and a punctured accumulator as an inner code.

Innovative Management of Budget Deficits: A Proportional Salary and Time Reduction Scheme.

ERIC Educational Resources Information Center

Sloper, David

1989-01-01

An approach to institutional budgeting designed to alleviate accumulated deficits is described. The proposal introduces flexibility into the salary component, alleviating cash flow difficulties in the short to medium term and encouraging more proactive budgeting, by allowing employees to contract for reduced annual salary in exchange for reduced…

Will the Australia-United States Free Trade Agreement undermine the Pharmaceutical Benefits Scheme?

PubMed

Harvey, Ken J; Faunce, Thomas A; Lokuge, Buddhima; Drahos, Peter

2004-09-06

The Australia-United States Free Trade Agreement (AUSFTA) contains major concessions to the US pharmaceutical industry that may undermine the egalitarian principles and operation of the Pharmaceutical Benefits Scheme (PBS) and substantially increase the costs of medicinal drugs to Australian consumers. AUSFTA's approach to the PBS excessively emphasises the need to reward manufacturers of "innovative" new pharmaceuticals, instead of emphasising consumers' need for equitable and affordable access to necessary medicines (the first principle of our National Medicines Policy). Several features of AUSFTA may bring pressure to bear on the Pharmaceutical Benefits Advisory Committee (PBAC) to list "innovative" drugs that the committee initially rejected because the evidence for cost-effectiveness was not compelling. Intellectual property provisions of AUSFTA are likely to delay the entry of PBS cost-reducing generic products when pharmaceutical patents expire. We support the many concerned health and consumer organisations who have asked the Senate either not to pass the enabling legislation, or to delay its passage until a fairer deal in terms of public health can be obtained.

Review: Modelling chemical kinetics and convective heating in giant planet entries

NASA Astrophysics Data System (ADS)

Reynier, Philippe; D'Ammando, Giuliano; Bruno, Domenico

2018-01-01

A review of the existing chemical kinetics models for H2 / He mixtures and related transport and thermodynamic properties is presented as a pre-requisite towards the development of innovative models based on the state-to-state approach. A survey of the available results obtained during the mission preparation and post-flight analyses of the Galileo mission has been undertaken and a computational matrix has been derived. Different chemical kinetics schemes for hydrogen/helium mixtures have been applied to numerical simulations of the selected points along the entry trajectory. First, a reacting scheme, based on literature data, has been set up for computing the flow-field around the probe at high altitude and comparisons with existing numerical predictions are performed. Then, a macroscopic model derived from a state-to-state model has been constructed and incorporated into a CFD code. Comparisons with existing numerical results from the literature have been performed as well as cross-check comparisons between the predictions provided by the different models in order to evaluate the potential of innovative chemical kinetics models based on the state-to-state approach.

65-nm full-chip implementation using double dipole lithography

NASA Astrophysics Data System (ADS)

Hsu, Stephen D.; Chen, J. Fung; Cororan, Noel; Knose, William T.; Van Den Broeke, Douglas J.; Laidig, Thomas L.; Wampler, Kurt E.; Shi, Xuelong; Hsu, Michael; Eurlings, Mark; Finders, Jo; Chiou, Tsann-Bim; Socha, Robert J.; Conley, Will; Hsieh, Yen W.; Tuan, Steve; Hsieh, Frank

2003-06-01

Double Dipole Lithography (DDL) has been demonstrated to be capable of patterning complex 2D patterns. Due to inherently high aerial imaging contrast, especially for dense features, we have found that it has a very good potential to meet manufacturing requirements for the 65nm node using ArF binary chrome masks. For patterning in the k1<0.35 regime without resorting to hard phase-shift masks (PSMs), DDL is one unique Resolution Enhancement Technique (RET) which can achieve an acceptable process window. To utilize DDL for printing actual IC devices, the original design data must be decomposed into "vertical (V)" and "horizontal (H)" masks for the respective X- and Y-dipole exposures. An improved two-pass, model-based, DDL mask data processing methodology has been established. It is capable of simultaneously converting complex logic and memory mask patterns into DDL compatible mask layout. To maximize the overlapped process window area, we have previously shown that the pattern-shielding algorithm must be intelligently applied together with both Scattering Bars (SBs) and model-based OPC (MOPC). Due to double exposures, stray light must be well-controlled to ensure uniform printing across the entire chip. One solution to minimize stray light is to apply large patches of solid chrome in open areas to reduce the background transmission during exposure. Unfortunately, this is not feasible for a typical clear-field poly gate masks to be patterned by a positive resist process. In this work, we report a production-worthy DDL mask pattern decomposition scheme for full-chip application. A new generation of DDL technology reticle set has been developed to verify the printing performance. Shielding is a critical part of the DDL. An innovative shielding scheme has been developed to protect the critical features and minimize the impact of stray light during double exposure.

Perception of temporally modified speech in auditory neuropathy.

PubMed

Hassan, Dalia Mohamed

2011-01-01

Disrupted auditory nerve activity in auditory neuropathy (AN) significantly impairs the sequential processing of auditory information, resulting in poor speech perception. This study investigated the ability of AN subjects to perceive temporally modified consonant-vowel (CV) pairs and shed light on their phonological awareness skills. Four Arabic CV pairs were selected: /ki/-/gi/, /to/-/do/, /si/-/sti/ and /so/-/zo/. The formant transitions in consonants and the pauses between CV pairs were prolonged. Rhyming, segmentation and blending skills were tested using words at a natural rate of speech and with prolongation of the speech stream. Fourteen adult AN subjects were compared to a matched group of cochlear-impaired patients in their perception of acoustically processed speech. The AN group distinguished the CV pairs at a low speech rate, in particular with modification of the consonant duration. Phonological awareness skills deteriorated in adult AN subjects but improved with prolongation of the speech inter-syllabic time interval. A rehabilitation program for AN should consider temporal modification of speech, training for auditory temporal processing and the use of devices with innovative signal processing schemes. Verbal modifications as well as visual imaging appear to be promising compensatory strategies for remediating the affected phonological processing skills.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sciarrino, Fabio; Dipartimento di Fisica and Consorzio Nazionale Interuniversitario per le Scienze Fisiche della Materia, Universita 'La Sapienza', Rome 00185; De Martini, Francesco

The optimal phase-covariant quantum cloning machine (PQCM) broadcasts the information associated to an input qubit into a multiqubit system, exploiting a partial a priori knowledge of the input state. This additional a priori information leads to a higher fidelity than for the universal cloning. The present article first analyzes different innovative schemes to implement the 1{yields}3 PQCM. The method is then generalized to any 1{yields}M machine for an odd value of M by a theoretical approach based on the general angular momentum formalism. Finally different experimental schemes based either on linear or nonlinear methods and valid for single photon polarizationmore » encoded qubits are discussed.« less

A Secret 3D Model Sharing Scheme with Reversible Data Hiding Based on Space Subdivision

NASA Astrophysics Data System (ADS)

Tsai, Yuan-Yu

2016-03-01

Secret sharing is a highly relevant research field, and its application to 2D images has been thoroughly studied. However, secret sharing schemes have not kept pace with the advances of 3D models. With the rapid development of 3D multimedia techniques, extending the application of secret sharing schemes to 3D models has become necessary. In this study, an innovative secret 3D model sharing scheme for point geometries based on space subdivision is proposed. Each point in the secret point geometry is first encoded into a series of integer values that fall within [0, p - 1], where p is a predefined prime number. The share values are derived by substituting the specified integer values for all coefficients of the sharing polynomial. The surface reconstruction and the sampling concepts are then integrated to derive a cover model with sufficient model complexity for each participant. Finally, each participant has a separate 3D stego model with embedded share values. Experimental results show that the proposed technique supports reversible data hiding and the share values have higher levels of privacy and improved robustness. This technique is simple and has proven to be a feasible secret 3D model sharing scheme.

Access to anti-cancer drugs in India: is there a need to revise reimbursement policies?

PubMed

Haitsma, Gertruud; Patel, Himanshu; Gurumurthy, Parthasarathi; Postma, Maarten J

2018-06-01

The aim of this study was to examine the access of Indian cancer patients to optimum cancer care under selected government schemes by reviewing reimbursement schemes for cancer care in India. All cancer care reimbursement schemes in India were identified and three highly utilized schemes (VAS, RAS, CMCHS) were selected. Quality of breast, colorectal, lung, head & neck, and gastric cancer care was reviewed with respect to NCCN guidelines. Direct medical costs and shortage of budget in reimbursed amounts were calculated for each listed chemotherapy regimen. Medical oncology practice following the schemes' formularies is inferior to recommendations by the NCCN guidelines. Innovative treatment (targeted therapies) like trastuzumab, pertuzumab (breast), bevacizumab, cetuximab, panitumumab (colorectal), erlotinib, gefitinib, crizotinib, and nivolumab (lung) are either not reimbursed (VAS, CMCHS) or partially reimbursed (RAS). Average shortage of budget was found to be 43% (breast), 55% (colorectal), 74% (lung), 7% (head & neck), and 51% (gastric cancer). Policy makers should consider addition of newer treatments, exclusion of sub-optimal treatments, increments in per patient budget and optimization of supportive care, which may contribute to improvements in survival and quality of life for Indian cancer patients.

Identification of complex stiffness tensor from waveform reconstruction

NASA Astrophysics Data System (ADS)

Leymarie, N.; Aristégui, C.; Audoin, B.; Baste, S.

2002-03-01

An inverse method is proposed in order to determine the viscoelastic properties of composite-material plates from the plane-wave transmitted acoustic field. Analytical formulations of both the plate transmission coefficient and its first and second derivatives are established, and included in a two-step inversion scheme. Two objective functions to be minimized are then designed by considering the well-known maximum-likelihood principle and by using an analytic signal formulation. Through these innovative objective functions, the robustness of the inversion process against high level of noise in waveforms is improved and the method can be applied to a very thin specimen. The suitability of the inversion process for viscoelastic property identification is demonstrated using simulated data for composite materials with different anisotropy and damping degrees. A study of the effect of the rheologic model choice on the elastic property identification emphasizes the relevance of using a phenomenological description considering viscosity. Experimental characterizations show then the good reliability of the proposed approach. Difficulties arise experimentally for particular anisotropic media.

Strategies for Efficient Charge Separation and Transfer in Artificial Photosynthesis of Solar Fuels.

PubMed

Xu, Yuxing; Li, Ailong; Yao, Tingting; Ma, Changtong; Zhang, Xianwen; Shah, Jafar Hussain; Han, Hongxian

2017-11-23

Converting sunlight to solar fuels by artificial photosynthesis is an innovative science and technology for renewable energy. Light harvesting, photogenerated charge separation and transfer (CST), and catalytic reactions are the three primary steps in the processes involved in the conversion of solar energy to chemical energy (SE-CE). Among the processes, CST is the key "energy pump and delivery" step in determining the overall solar-energy conversion efficiency. Efficient CST is always high priority in designing and assembling artificial photosynthesis systems for solar-fuel production. This Review not only introduces the fundamental strategies for CST but also the combinatory application of these strategies to five types of the most-investigated semiconductor-based artificial photosynthesis systems: particulate, Z-scheme, hybrid, photoelectrochemical, and photovoltaics-assisted systems. We show that artificial photosynthesis systems with high SE-CE efficiency can be rationally designed and constructed through combinatory application of these strategies, setting a promising blueprint for the future of solar fuels. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Study on Product Innovative Design Process Driven by Ideal Solution

NASA Astrophysics Data System (ADS)

Zhang, Fuying; Lu, Ximei; Wang, Ping; Liu, Hui

Product innovative design in companies today relies heavily on individual members’ experience and creative ideation as well as their skills of integrating creativity and innovation tools with design methods agilely. Creative ideation and inventive ideas generation are two crucial stages in product innovative design process. Ideal solution is the desire final ideas for given problem, and the striving reaching target for product design. In this paper, a product innovative design process driven by ideal solution is proposed. This design process encourages designers to overcome their psychological inertia, to foster creativity in a systematic way for acquiring breakthrough creative and innovative solutions in a reducing sphere of solution-seeking, and results in effective product innovative design rapidly. A case study example is also presented to illustrate the effectiveness of the proposed design process.

Second Careers for Women. A View from the San Francisco Peninsula.

ERIC Educational Resources Information Center

Fairbank, Jane D., Ed.; Bell, Susan Groag, Ed.

The Second Careers for Women conference is discussed as to its evolution and place in the scheme of continuing education programs for women. The keynote address, "A Decade of Innovation," by Martha Sturm White is reproduced, and summaries of 15 workshops are provided. The workshop summaries depict the situation for adult women seeking…

Language Learning and the Raising of Cultural Awareness through Internet Telephony: A Case Study

ERIC Educational Resources Information Center

Polisca, Elena

2011-01-01

This article seeks to assess the impact of V-Pal (Virtual Partnerships for All Languages) on the student language learning experience within a conventional UK higher education (HE) curriculum. V-Pal is an innovative computer-mediated language scheme, based on a reciprocal, distance-learning language project, run by the University of Manchester in…

Social Service Community Education as an Area of Training and Participation for Social Development

ERIC Educational Resources Information Center

García, Amelia Molina

2012-01-01

This paper presents the conditions and characteristics of a rural community education program in the Mexican context. The scheme of operation and participation of young people called Community Instructors (Instructores Comunitarios or IC) is innovative and worthy of recognition as a learning area, not only for school purposes but as one which…

The House System: Evaluating Its Role in the Experience of Business Students

ERIC Educational Resources Information Center

Antoniadou, Marilena

2017-01-01

This paper presents a case study of students' experiences of the House system, an innovative scheme introduced for business students, aiming to enhance student experience. The findings are based on a survey of 350 students and 4 group interviews. Analysis of the findings, both statistical and qualitative, indicated perceived clear benefits for the…

Course Management Systems and Blended Learning: An Innovative Learning Approach

ERIC Educational Resources Information Center

Chou, Amy Y.; Chou, David C.

2011-01-01

This article utilizes Rogers' innovation-decision process model (2003) and Beckman and Berry's innovation process model (2007) to create an innovative learning map that illustrates three learning methods (i.e., face-to-face learning, online learning, and blended learning) in two types of innovation (i.e., incremental innovation and radical…

78 FR 40627 - Prohibitions and Conditions on the Importation and Exportation of Rough Diamonds

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-08

... November 5, 2002, the launch of the Kimberley Process Certification Scheme (KPCS) for rough diamonds. Under... implements the Kimberley Process Certification Scheme (KPCS) for rough diamonds. The KPCS is a process, based... not been controlled through the Kimberley Process Certification Scheme. By Executive Order 13312 dated...

A strategy for the implementation of a quality indicator system in German primary care.

PubMed

van den Heuvel, Henricus

2011-01-01

The Quality and Outcomes Framework (QOF) has had a major impact on the quality of care in British general practice. It is seen as a major innovation amongst quality indicator systems and as a result various countries are looking at whether such initiatives could be used in their primary care. In Germany also the development of similar schemes has started. To propose a strategy indicating key issues for the implementation of a quality indicator scheme in German primary care. Literature review with a focus on the QOF and German quality indicator literature. There are major differences between the German and British healthcare and primary care systems. The development of quality indicator systems for German general practice is in progress and there is a net force for the implementation of such systems. The following ten key factors are suggested for the successful implementation of such a system in German primary care: involvement of general practitioners (GPs) at all levels of the development, a clear implementation process, investment in practice information technology (IT) systems, an accepted quality indicator set, a quality indicator setting institution and data collection organisation, clear financial and non-financial incentives, a 'practice registration' structure, an exception reporting mechanism, delegation of routine clinical data collection tasks to practice assistants, a stepped implementation approach and adequate evaluation processes. For the successful implementation of a quality indicator system in German primary care a number of key issues, as presented in this article, need to be taken into account.

Assessing and Improving the Quality of Food Composition Databases for Nutrition and Health Applications in Europe: The Contribution of EuroFIR123

PubMed Central

Finglas, Paul M.; Berry, Rachel; Astley, Siân

2014-01-01

Food composition databases (FCDBs) form an integral part of nutrition and health research, patient treatment, manufacturing processes, and consumer information. FCDBs have traditionally been compiled at a national level; therefore, until recently, there was limited standardization of procedures across different data sets. Digital technologies now allow FCDB users to access a variety of information from different sources, which has emphasized the need for greater harmonization. The European Food Information Resource (EuroFIR) Network of Excellence and Nexus projects (2005–2013) has been instrumental in addressing differences in FCDBs and in producing standardized protocols and quality schemes to compile and manage them. A formal, recognized European standard for food composition data has been prepared, which will further assist in the production of comparable data. Quality schemes need to address both the composition data, plus the methods of sampling, analysis, and calculation, and the documentation of processes. The EuroFIR data exchange platform provides a wealth of resources for composition compilers and end users and continues to develop new and innovative tools and methodologies. EuroFIR also is working in collaboration with the European Food Safety Authority, and as a partner in several European projects. Through such collaborations, EuroFIR will continue to develop FCDB harmonization and to use new technologies to ensure sustainable future initiatives in the food composition activities that underpin food and health research in Europe. PMID:25469406

Rethinking Communication in Innovation Processes: Creating Space for Change in Complex Systems

ERIC Educational Resources Information Center

Leeuwis, Cees; Aarts, Noelle

2011-01-01

This paper systematically rethinks the role of communication in innovation processes, starting from largely separate theoretical developments in communication science and innovation studies. Literature review forms the basis of the arguments presented. The paper concludes that innovation is a collective process that involves the contextual…

Enhancement of DRPE performance with a novel scheme based on new RAC: Principle, security analysis and FPGA implementation

NASA Astrophysics Data System (ADS)

Neji, N.; Jridi, M.; Alfalou, A.; Masmoudi, N.

2016-02-01

The double random phase encryption (DRPE) method is a well-known all-optical architecture which has many advantages especially in terms of encryption efficiency. However, the method presents some vulnerabilities against attacks and requires a large quantity of information to encode the complex output plane. In this paper, we present an innovative hybrid technique to enhance the performance of DRPE method in terms of compression and encryption. An optimized simultaneous compression and encryption method is applied simultaneously on the real and imaginary components of the DRPE output plane. The compression and encryption technique consists in using an innovative randomized arithmetic coder (RAC) that can well compress the DRPE output planes and at the same time enhance the encryption. The RAC is obtained by an appropriate selection of some conditions in the binary arithmetic coding (BAC) process and by using a pseudo-random number to encrypt the corresponding outputs. The proposed technique has the capabilities to process video content and to be standard compliant with modern video coding standards such as H264 and HEVC. Simulations demonstrate that the proposed crypto-compression system has presented the drawbacks of the DRPE method. The cryptographic properties of DRPE have been enhanced while a compression rate of one-sixth can be achieved. FPGA implementation results show the high performance of the proposed method in terms of maximum operating frequency, hardware occupation, and dynamic power consumption.

Resonance fluorescence and quantum interference of a single NV center

NASA Astrophysics Data System (ADS)

Ma, Yong-Hong; Zhang, Xue-Feng; Wu, E.

2017-11-01

The detection of a single nitrogen-vacancy center in diamond has attracted much interest, since it is expected to lead to innovative applications in various domains of quantum information, including quantum metrology, information processing and communications, as well as in various nanotechnologies, such as biological and subdiffraction limit imaging, and tests of entanglement in quantum mechanics. We propose a novel scheme of a single NV center coupled with a multi-mode superconducting microwave cavity driven by coherent fields in squeezed vacuum. We numerically investigate the spectra in-phase quadrature and out-of-phase quadrature for different driving regimes with or without detunings. It shows that the maximum squeezing can be obtained for optimal Rabi fields. Moreover, with the same parameters, the maximum squeezing is greatly increased when the detunings are nonzero compared to the resonance case.

Improving the secrecy rate by turning foes to allies: An auction scheme

NASA Astrophysics Data System (ADS)

Ma, Ya-Yan; Wang, Bao-Yun

2015-09-01

Security against eavesdroppers is a critical issue in cognitive radio networks (CRNs). In this paper, a scenario consisting of one primary pair and multiple secondary pairs is considered. The secondary transmitters (STs) work in half-duplex mode and they are potential eavesdroppers on the primary transmission unless they are allowed to simultaneously transmit with the primary transmitter (PT). A modified second-price sealed-bid auction scheme is employed to model the interaction between the PT and STs. With the proposed auction scheme, the hostile relationship between the PT and STs is transformed into a cooperative relationship. An iterative algorithm based on the max-min criteria is proposed to find the optimal bidding power of the STs for an access chance in the presence of multiple eavesdroppers. Numerical results show that the proposed auction scheme not only improves the PT’s security but also increases the access opportunities of the STs. Project supported by the National Natural Science Foundation of China (Grant Nos. 61271232 and 61372126) and the University Postgraduate Research and Innovation Project in Jiangsu Province, China (Grant No. CXZZ12-0472).

Modeling operation of mechanism of holistic management of technological processes at enterprise

NASA Astrophysics Data System (ADS)

Igorevich Shanin, Igor; Aleksandrovna Boris, Olga

2018-03-01

Enterprises applying modeling and technological process management approaches represent a sector of a new innovative economic system. First of all, they are innovators using innovative proposals and various resources to solve practical problems. Their work leads to balanced positive technological changes. In other words, they constitute industrial entrepreneurship with innovative goals and vice versa - innovative entrepreneurship with industrial objectives. It should be noted that the mechanism of holistic management of technological processes at the enterprise combines a traditional industrial organization of production, an innovative and technological enterprise. The enterprise borrows industrial targets from the latter one, an innovative component - from innovative activity and entrepreneurial approaches to holistic management - from a commercial firm.

Application of Improved 5th-Cubature Kalman Filter in Initial Strapdown Inertial Navigation System Alignment for Large Misalignment Angles.

PubMed

Wang, Wei; Chen, Xiyuan

2018-02-23

In view of the fact the accuracy of the third-degree Cubature Kalman Filter (CKF) used for initial alignment under large misalignment angle conditions is insufficient, an improved fifth-degree CKF algorithm is proposed in this paper. In order to make full use of the innovation on filtering, the innovation covariance matrix is calculated recursively by an innovative sequence with an exponent fading factor. Then a new adaptive error covariance matrix scaling algorithm is proposed. The Singular Value Decomposition (SVD) method is used for improving the numerical stability of the fifth-degree CKF in this paper. In order to avoid the overshoot caused by excessive scaling of error covariance matrix during the convergence stage, the scaling scheme is terminated when the gradient of azimuth reaches the maximum. The experimental results show that the improved algorithm has better alignment accuracy with large misalignment angles than the traditional algorithm.

Counter-Based Broadcast Scheme Considering Reachability, Network Density, and Energy Efficiency for Wireless Sensor Networks.

PubMed

Jung, Ji-Young; Seo, Dong-Yoon; Lee, Jung-Ryun

2018-01-04

A wireless sensor network (WSN) is emerging as an innovative method for gathering information that will significantly improve the reliability and efficiency of infrastructure systems. Broadcast is a common method to disseminate information in WSNs. A variety of counter-based broadcast schemes have been proposed to mitigate the broadcast-storm problems, using the count threshold value and a random access delay. However, because of the limited propagation of the broadcast-message, there exists a trade-off in a sense that redundant retransmissions of the broadcast-message become low and energy efficiency of a node is enhanced, but reachability become low. Therefore, it is necessary to study an efficient counter-based broadcast scheme that can dynamically adjust the random access delay and count threshold value to ensure high reachability, low redundant of broadcast-messages, and low energy consumption of nodes. Thus, in this paper, we first measure the additional coverage provided by a node that receives the same broadcast-message from two neighbor nodes, in order to achieve high reachability with low redundant retransmissions of broadcast-messages. Second, we propose a new counter-based broadcast scheme considering the size of the additional coverage area, distance between the node and the broadcasting node, remaining battery of the node, and variations of the node density. Finally, we evaluate performance of the proposed scheme compared with the existing counter-based broadcast schemes. Simulation results show that the proposed scheme outperforms the existing schemes in terms of saved rebroadcasts, reachability, and total energy consumption.

Secure Distributed Detection under Energy Constraint in IoT-Oriented Sensor Networks.

PubMed

Zhang, Guomei; Sun, Hao

2016-12-16

We study the secure distributed detection problems under energy constraint for IoT-oriented sensor networks. The conventional channel-aware encryption (CAE) is an efficient physical-layer secure distributed detection scheme in light of its energy efficiency, good scalability and robustness over diverse eavesdropping scenarios. However, in the CAE scheme, it remains an open problem of how to optimize the key thresholds for the estimated channel gain, which are used to determine the sensor's reporting action. Moreover, the CAE scheme does not jointly consider the accuracy of local detection results in determining whether to stay dormant for a sensor. To solve these problems, we first analyze the error probability and derive the optimal thresholds in the CAE scheme under a specified energy constraint. These results build a convenient mathematic framework for our further innovative design. Under this framework, we propose a hybrid secure distributed detection scheme. Our proposal can satisfy the energy constraint by keeping some sensors inactive according to the local detection confidence level, which is characterized by likelihood ratio. In the meanwhile, the security is guaranteed through randomly flipping the local decisions forwarded to the fusion center based on the channel amplitude. We further optimize the key parameters of our hybrid scheme, including two local decision thresholds and one channel comparison threshold. Performance evaluation results demonstrate that our hybrid scheme outperforms the CAE under stringent energy constraints, especially in the high signal-to-noise ratio scenario, while the security is still assured.

Secure Distributed Detection under Energy Constraint in IoT-Oriented Sensor Networks

PubMed Central

Zhang, Guomei; Sun, Hao

2016-01-01

We study the secure distributed detection problems under energy constraint for IoT-oriented sensor networks. The conventional channel-aware encryption (CAE) is an efficient physical-layer secure distributed detection scheme in light of its energy efficiency, good scalability and robustness over diverse eavesdropping scenarios. However, in the CAE scheme, it remains an open problem of how to optimize the key thresholds for the estimated channel gain, which are used to determine the sensor’s reporting action. Moreover, the CAE scheme does not jointly consider the accuracy of local detection results in determining whether to stay dormant for a sensor. To solve these problems, we first analyze the error probability and derive the optimal thresholds in the CAE scheme under a specified energy constraint. These results build a convenient mathematic framework for our further innovative design. Under this framework, we propose a hybrid secure distributed detection scheme. Our proposal can satisfy the energy constraint by keeping some sensors inactive according to the local detection confidence level, which is characterized by likelihood ratio. In the meanwhile, the security is guaranteed through randomly flipping the local decisions forwarded to the fusion center based on the channel amplitude. We further optimize the key parameters of our hybrid scheme, including two local decision thresholds and one channel comparison threshold. Performance evaluation results demonstrate that our hybrid scheme outperforms the CAE under stringent energy constraints, especially in the high signal-to-noise ratio scenario, while the security is still assured. PMID:27999282

78 FR 12135 - List of Participating Countries and Entities (Hereinafter Known as “Participants”) Under the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

... has not been controlled through the Kimberley Process Certification Scheme (KPCS). Under Section 3(2) of the Act, ``controlled through the Kimberley Process Certification Scheme'' means an importation... Kimberley Process Certification Scheme. Angola--Ministry of Geology and Mines. Armenia--Ministry of Trade...

Innovations in connected health.

PubMed

Singh, Kanwaljit; Kvedar, Joseph C

2009-01-01

Technological advancements in recent decades have made the concept of Connected Health feasible. These innovations include hardware innovations (such as wearable medical technology), and software (such as electronic personal health record systems e.g., Google Health and Microsoft HealthVault). Technology innovations must be accompanied by process innovations to truly add value. In health care that includes clinical process innovations and business process innovations. This chapter outlines how the healthcare system is being affected by innovations in connected health. It provides examples that illustrate the various categories of innovation and their impact. Now more than ever, health care reform is required in the U.S. The systems outlined in this chapter will allow care that is of high quality, while extending providers across more patients (i.e. increasing access) at a lower overall cost (improved efficiency).

A Framework to Move Forward on the Path to Eco-innovation in the Construction Industry: Implications to Improve Firms' Sustainable Orientation.

PubMed

Segarra-Oña, María-del-Val; Peiró-Signes, Angel; Cervelló-Royo, Roberto

2015-12-01

This paper examines key aspects in the innovative behavior of the construction firms that determine their environmental orientation while innovating. Structural equation modeling was used and data of 222 firms retrieved from the Spanish Technological Innovation Panel (PITEC) for 2010 to analyse the drivers of environmental orientation of the construction firms during the innovation process. The results show that the environmental orientation is positively affected by the product and process orientation of construction firms during the innovation process. Furthermore, the positive relation between the importance of market information sources and environmental orientation, mediated by process and product orientation, is discussed. Finally, a model that explains these relations is proposed and validated. Results have important managerial implications for those companies worried about their eco-innovative focus as the types of actions and relations within firms most suitable for improving their eco-innovative orientation are highlighted.

Flight data results of estimate fusion for spacecraft rendezvous navigation from shuttle mission STS-69

NASA Technical Reports Server (NTRS)

Carpenter, J. Russell; Bishop, Robert H.

1996-01-01

A recently developed rendezvous navigation fusion filter that optimally exploits existing distributed filters for rendezvous and GPS navigation to achieve the relative and inertial state accuracies of both in a global solution is utilized here to process actual flight data. Space Shuttle Mission STS-69 was the first mission to date which gathered data from both the rendezvous and Global Positioning System filters allowing, for the first time, a test of the fusion algorithm with real flight data. Furthermore, a precise best estimate of trajectory is available for portions of STS-69, making possible a check on the performance of the fusion filter. In order to successfully carry out this experiment with flight data, two extensions to the existing scheme were necessary: a fusion edit test based on differences between the filter state vectors, and an underweighting scheme to accommodate the suboptimal perfect target assumption made by the Shuttle rendezvous filter. With these innovations, the flight data was successfully fused from playbacks of downlinked and/or recorded measurement data through ground analysis versions of the Shuttle rendezvous filter and a GPS filter developed for another experiment. The fusion results agree with the best estimate of trajectory at approximately the levels of uncertainty expected from the fusion filter's covariance matrix.

A review of optimization and quantification techniques for chemical exchange saturation transfer (CEST) MRI toward sensitive in vivo imaging

PubMed Central

Guo, Yingkun; Zheng, Hairong; Sun, Phillip Zhe

2015-01-01

Chemical exchange saturation transfer (CEST) MRI is a versatile imaging method that probes the chemical exchange between bulk water and exchangeable protons. CEST imaging indirectly detects dilute labile protons via bulk water signal changes following selective saturation of exchangeable protons, which offers substantial sensitivity enhancement and has sparked numerous biomedical applications. Over the past decade, CEST imaging techniques have rapidly evolved due to contributions from multiple domains, including the development of CEST mathematical models, innovative contrast agent designs, sensitive data acquisition schemes, efficient field inhomogeneity correction algorithms, and quantitative CEST (qCEST) analysis. The CEST system that underlies the apparent CEST-weighted effect, however, is complex. The experimentally measurable CEST effect depends not only on parameters such as CEST agent concentration, pH and temperature, but also on relaxation rate, magnetic field strength and more importantly, experimental parameters including repetition time, RF irradiation amplitude and scheme, and image readout. Thorough understanding of the underlying CEST system using qCEST analysis may augment the diagnostic capability of conventional imaging. In this review, we provide a concise explanation of CEST acquisition methods and processing algorithms, including their advantages and limitations, for optimization and quantification of CEST MRI experiments. PMID:25641791

Amsterdam's STI/HIV Programme: An Innovative Strategy to Achieve and Enhance the Participation of Migrant Community-Based Organisations

ERIC Educational Resources Information Center

Wagemakers, Annemarie; van Husen, Gwen; Barrett, Jennifer B.; Koelen, Maria A.

2015-01-01

Objective: The STI/HIV prevention programme in Amsterdam aims to improve the sexual health of Amsterdam residents of African, Antillean, Aruban and Surinamese origins. The programme strategy is to achieve and enhance the participation of migrant community-based organisations (CBOs) in sexual health promotion through a grant scheme and by providing…

Toward the Automated Scoring of Written Arguments: Developing an Innovative Approach for Annotation. Research Report. ETS RR-17-11

ERIC Educational Resources Information Center

Song, Yi; Deane, Paul; Beigman Klebanov, Beata

2017-01-01

This project focuses on laying the foundations for automated analysis of argumentation schemes, supporting identification and classification of the arguments being made in a text, for the purpose of scoring the quality of written analyses of arguments. We developed annotation protocols for 20 argument prompts from a college-level test under the…

OFT, VBP: QED?

PubMed

Claxton, Karl

2007-06-01

The report by the Office of Fair Trading (OFT) on the UK pharmaceutical price regulation scheme (PPRS) recommends the reform of the current scheme, which is a combination of profit and price controls, to one where price is based on the health benefits offered by a pharmaceutical. On closer examination some of the more commonly expressed concerns about these proposals do not seem to be well founded. In principle, the OFT's recommendations may contribute to allocative and dynamic efficiency in the NHS. However, there are some dangers and the details of how it will be implemented are crucial. For example, value-based pricing with an inappropriate threshold for cost-effectiveness, or an inappropriate pricing structure, could lead to technologies being adopted at prices where their benefits, in terms of health outcome, do not offset the health displaced elsewhere in the NHS, a situation in which the NHS is damaged rather than improved by innovation. A failure to account for uncertainty and the value of evidence in negotiating prices and coverage could also undermine the evidence base for future NHS practice. Whatever view is taken, the OFT report will inevitably shape the scope of future policy debates about value, guidance, price and innovation.

77 FR 27831 - List of Participating Countries and Entities Under the Clean Diamond Trade Act of 2003

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... Kimberley Process Certification Scheme (KPCS). Under Section 3(2) of the Act, ``controlled through the Kimberley Process Certification Scheme'' means an importation from the territory of a Participant or... Participants in the Kimberley Process Certification Scheme. Angola--Ministry of Geology and Mines. Armenia...

31 CFR 592.201 - Prohibited importation and exportation of any rough diamond; permitted importation or exportation...

Code of Federal Regulations, 2010 CFR

2010-07-01

..., unless the rough diamond has been controlled through the Kimberley Process Certification Scheme. (b) The... States of any rough diamond not controlled through the Kimberley Process Certification Scheme do not... Process Certification Scheme and thus is not permitted, except in the following circumstance. The...

The value of innovation in decision-making in health care in Central Eastern Europe - The Sixth International Conference, 2 June 2017, Belgrade, Serbia.

PubMed

Novakovic, Tanja; Martin, Antony P; Parker, Mark; Ferrario, Alessandra; Vukovic, Simo; Łanda, Krzysztof; Duba, Jaroslav; Dankó, Dávid; Kotsopoulos, Nikolaos; Godman, Brian; Ristic, Jelena; Stefanovic, Danka; Tesic, Danka

2017-12-01

The Pharmacoeconomics Section of the Pharmaceutical Association of Serbia organised a one day international conference on the value of innovation in decision-making in health care in Central and Eastern Europe. The focus of the conference was on reimbursement decisions for medicines using health technology assessment and the use of managed entry agreements (MEAs). The objectives of this conference were firstly to discuss the challenges and opportunities with the use of MEAs in Central and Eastern European countries; secondly the role of patient registries especially with outcome based schemes, and finally new approaches to improve accessibility to new medicines including better managing their entry.

Backing the winners and the research infrastructure.

PubMed

Leliveld, H

1985-04-26

The industrial policy of the Dutch government is a priority area policy, that backs the winners of today and, even more, the potential winners of tomorrow. Important elements of this policy are the selection of high-chance activities, setting up new and informal relationships, promoting co-operation and supporting industrial research and development. To this end the government has set up Innovative Research Programmes and an Innovation Stimulation Scheme. Co-operation of universities and industry is essential for these programmes to succeed. Also international co-operation is a precondition to a firm position of European industry. The establishment of the Center for Bio-Pharmaceutical Sciences is entirely in line with the objectives of this policy.

Managing Distributed Innovation Processes in Virtual Organizations by Applying the Collaborative Network Relationship Analysis

NASA Astrophysics Data System (ADS)

Eschenbächer, Jens; Seifert, Marcus; Thoben, Klaus-Dieter

Distributed innovation processes are considered as a new option to handle both the complexity and the speed in which new products and services need to be prepared. Indeed most research on innovation processes was focused on multinational companies with an intra-organisational perspective. The phenomena of innovation processes in networks - with an inter-organisational perspective - have been almost neglected. Collaborative networks present a perfect playground for such distributed innovation processes whereas the authors highlight in specific Virtual Organisation because of their dynamic behaviour. Research activities supporting distributed innovation processes in VO are rather new so that little knowledge about the management of such research is available. With the presentation of the collaborative network relationship analysis this gap will be addressed. It will be shown that a qualitative planning of collaboration intensities can support real business cases by proving knowledge and planning data.

How orangutans (Pongo pygmaeus) innovate for water.

PubMed

Russon, Anne E; Kuncoro, Purwo; Ferisa, Agnes; Handayani, Dwi Putri

2010-02-01

We report an observational field study that aimed to identify innovative processes in rehabilitant orangutans' (Pongo pygmaeus) water innovations on Kaja Island, Central Kalimantan, Indonesia. We tested for the basic model of innovating (make small changes to old behavior), 4 contributors (apply old behavior to new ends, accidents, independent working out, social cross-fertilization), development, and social rank. Focal observations of Kaja rehabilitants' behavior over 20 months yielded 18 probable innovations from among 44 water variants. We identified variants by function and behavioral grain, innovations by prevalence, and innovative processes by relations between innovations, other behaviors, and social encounters. Findings indicate innovating by small changes and some involvement of all 4 contributors; midrank orangutans were the most innovative; and rehabilitants' adolescent age profile, orphaning, and intense sociality probably enhanced innovativeness. Important complexities include: orangutan innovating may favor certain behavioral levels and narrowly defined similarities, and it may constitute a phase-like process involving a succession of changes and contributors. Discussion focuses on links with great ape cognition and parallels with innovating in humans and other nonhuman species.

Innovation and participation for healthy public policy: the first National Health Assembly in Thailand

PubMed Central

Rasanathan, Kumanan; Posayanonda, Tipicha; Birmingham, Maureen; Tangcharoensathien, Viroj

2011-01-01

Abstract Aim  This paper aims to describe and disseminate the process and initial outcomes of the first National Health Assembly (NHA) in Thailand, as an innovative example of health policy making. Setting  The first NHA, held in December 2008 in Bangkok, brought together over 1500 people from government agencies, academia, civil society, health professionals and the private sector to discuss key health issues and produce resolutions to guide policy making. It adapted the approach used at the World Health Assembly of the World Health Organization. Method  Findings are derived from a literature review, document analysis, and the views and experiences of the authors, two of whom contributed to the organization of the NHA and two of whom were invited external observers. Results  Fourteen agenda items were discussed and resolutions passed. Potential early impacts on policy making have included an increase in the 2010 public budget for Thailand’s universal health coverage scheme as total public expenditure has decreased; cabinet endorsement of proposed Strategies for Universal Access to Medicines for Thai People; and establishment of National Commissions on Health Impact Assessment and Trade and Health. Discussion  The NHA was successful in bringing together various actors and sectors involved in the social production of health, including groups often marginalized in policy making. It provides an innovative model of how governments may be able to increase public participation and intersectoral collaboration that could be adapted in other contexts. Significant challenges remain in ensuring full participation of interested groups and in implementing, and monitoring the impact of, the resolutions passed. PMID:21281413

Innovation and participation for healthy public policy: the first National Health Assembly in Thailand.

PubMed

Rasanathan, Kumanan; Posayanonda, Tipicha; Birmingham, Maureen; Tangcharoensathien, Viroj

2012-03-01

This paper aims to describe and disseminate the process and initial outcomes of the first National Health Assembly (NHA) in Thailand, as an innovative example of health policy making. The first NHA, held in December 2008 in Bangkok, brought together over 1500 people from government agencies, academia, civil society, health professionals and the private sector to discuss key health issues and produce resolutions to guide policy making. It adapted the approach used at the World Health Assembly of the World Health Organization. Findings are derived from a literature review, document analysis, and the views and experiences of the authors, two of whom contributed to the organization of the NHA and two of whom were invited external observers. Fourteen agenda items were discussed and resolutions passed. Potential early impacts on policy making have included an increase in the 2010 public budget for Thailand's universal health coverage scheme as total public expenditure has decreased; cabinet endorsement of proposed Strategies for Universal Access to Medicines for Thai People; and establishment of National Commissions on Health Impact Assessment and Trade and Health. The NHA was successful in bringing together various actors and sectors involved in the social production of health, including groups often marginalized in policy making. It provides an innovative model of how governments may be able to increase public participation and intersectoral collaboration that could be adapted in other contexts. Significant challenges remain in ensuring full participation of interested groups and in implementing, and monitoring the impact of, the resolutions passed. © 2011 Blackwell Publishing Ltd.

Problem Solving Process Research of Everyone Involved in Innovation Based on CAI Technology

NASA Astrophysics Data System (ADS)

Chen, Tao; Shao, Yunfei; Tang, Xiaowo

It is very important that non-technical department personnel especially bottom line employee serve as innovators under the requirements of everyone involved in innovation. According the view of this paper, it is feasible and necessary to build everyone involved in innovation problem solving process under Total Innovation Management (TIM) based on the Theory of Inventive Problem Solving (TRIZ). The tools under the CAI technology: How TO mode and science effects database could be very useful for all employee especially non-technical department and bottom line for innovation. The problem solving process put forward in the paper focus on non-technical department personnel especially bottom line employee for innovation.

Oxidation of alkylaromatics - Analysis of an innovation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pohlman, H.P.; Leipold, H.A.; Meyer, D.H.

The effort by Standard Oil Co. (Indiana) through its subsidiary, Amoco Chemicals Corporation, to develop and commercialize a process for oxidizing alkylaromatics to their corresponding carboxylic acids is one of the major success stories in the chemical industry in the last 25 years. It represents the dedicated efforts of many people both within and outside the company who developed and applied state-of-the-art knowledge in many different technologies (1-3). The initial catalyzed air oxidation process scheme produced a variety of aromatic acids, but this paper focuses on the single product process for producing terephthalic acid from paraxylene. The commercial importance ofmore » terephthalic acid and its di-ester, dimethylterephthalate, lies in the production of poly-(ethylene terephthalate) (PET). This linear polymer is used in the manufacture of polyester fiber for clothing and home furnishing and industrial applications such as tire cord and conveyor belts. PET is also the base material for audio and video recording tapes and photographic films. Laminated polyester finds application in a variety of food packaging items while, as a molding resin, PET is used to make shatter-proof, lightweight bottles for soft drinks and, most recently, for alcoholic beverages (4-16). We believe there are several key lessons which can be learned from this innovation: 1. It is important to set good objectives, compatible with resources and opportunities of the company. 2. The key invention may be found outside the organization, no matter how hard we try or how good our own people are. 3. Firm commitment by management brings out the best in people. 4. Aggressive commercialization may be more effective than first completing all possible development work. It is necessary, however, to obtain good fundamental data if one wants to skip expensive pilot plants.« less

The Relationship between Creative Personality Composition, Innovative Team Climate, and Team Innovativeness: An Input-Process-Output Perspective

ERIC Educational Resources Information Center

Mathisen, Gro Ellen; Martinsen, Oyvind; Einarsen, Stale

2008-01-01

This study investigates the relationship between creative personality composition, innovative team climate, and team innovation based on an input-process-output model. We measured personality with the Creative Person Profile, team climate with the Team Climate Inventory, and team innovation through team-member and supervisor reports of team…

Structural and parameteric uncertainty quantification in cloud microphysics parameterization schemes

NASA Astrophysics Data System (ADS)

van Lier-Walqui, M.; Morrison, H.; Kumjian, M. R.; Prat, O. P.; Martinkus, C.

2017-12-01

Atmospheric model parameterization schemes employ approximations to represent the effects of unresolved processes. These approximations are a source of error in forecasts, caused in part by considerable uncertainty about the optimal value of parameters within each scheme -- parameteric uncertainty. Furthermore, there is uncertainty regarding the best choice of the overarching structure of the parameterization scheme -- structrual uncertainty. Parameter estimation can constrain the first, but may struggle with the second because structural choices are typically discrete. We address this problem in the context of cloud microphysics parameterization schemes by creating a flexible framework wherein structural and parametric uncertainties can be simultaneously constrained. Our scheme makes no assuptions about drop size distribution shape or the functional form of parametrized process rate terms. Instead, these uncertainties are constrained by observations using a Markov Chain Monte Carlo sampler within a Bayesian inference framework. Our scheme, the Bayesian Observationally-constrained Statistical-physical Scheme (BOSS), has flexibility to predict various sets of prognostic drop size distribution moments as well as varying complexity of process rate formulations. We compare idealized probabilistic forecasts from versions of BOSS with varying levels of structural complexity. This work has applications in ensemble forecasts with model physics uncertainty, data assimilation, and cloud microphysics process studies.

Towards improved photovoltaic conversion using dilute magnetic semiconductors (abstract only)

NASA Astrophysics Data System (ADS)

Olsson, Pär; Guillemoles, J.-F.; Domain, C.

2008-02-01

Present photovoltaic devices, based on p/n junctions, are limited from first principles to maximal efficiencies of 31% (40% under full solar concentration; Shockley and Queisser 1961 J. Appl. Phys. 32 510). However, more innovative schemes may overcome the Shockley-Queisser limit since the theoretical maximal efficiency of solar energy conversion is higher than 85% (Harder and Würfel 2003 Semicond. Sci. Technol. 18 S151). To date, the only practical realization of such an innovative scheme has been multi-junction devices, which at present hold the world record for efficiency at nearly 41% at significant solar concentration (US DOE news site: http://www.energy.gov/news/4503.htm). It has been proposed that one could make use of the solar spectrum in much the same way as the multi-junction devices do but in a single cell, using impurity induced intermediate levels to create gaps of different sizes. This intermediate level semiconductor (ILSC) concept (Green and Wenham 1994 Appl. Phys. Lett. 65 2907; Luque and Martí1997 Phys. Rev. Lett. 78 5014) has a maximal efficiency similar to that of multi-junction devices but suffers from prohibitively large non-radiative recombination rates. We here propose to use a ferromagnetic impurity scheme in order to reduce the non-radiative recombination rates while maintaining the high theoretical maximum efficiency of the ILSC scheme, that is about 46%. Using density functional theory calculations, the electronic and energetic properties of transition metal impurities for a wide range of semiconductors have been analysed. Of the several hundred compounds studied, only a few fulfil the design criteria that we present here. As an example, wide gap AlP is one of the most promising compounds. It was found that inclusion of significant amounts of Mn in AlP induces band structures providing conversion efficiencies potentially close to the theoretical maximum, with an estimated Curie temperature reaching above 100 K.

Quality Assurance in Environmental Technology Verification (ETV): Analysis and Impact on the EU ETV Pilot Programme Performance

NASA Astrophysics Data System (ADS)

Molenda, Michał; Ratman-Kłosińska, Izabela

2018-03-01

Many innovative environmental technologies never reach the market because they are new and cannot demonstrate a successful track record of previous applications. This fact is a serious obstacle on their way to the market. Lack of credible data on the performance of a technology causes mistrust of investors in innovations, especially from public sector, who seek effective solutions however without compromising the technical and financial risks associated with their implementation. Environmental technology verification (ETV) offers a credible, robust and transparent process that results in a third party confirmation of the claims made by the providers about the performance of the novel environmental technologies. Verifications of performance are supported by high quality, independent test data. In that way ETV as a tool helps establish vendor credibility and buyer confidence. Several countries across the world have implemented ETV in the form of national or regional programmes. ETV in the European Union was implemented as a voluntary scheme if a form of a pilot programme. The European Commission launched the Environmental Technology Pilot Programme of the European Union (EU ETV) in 2011. The paper describes the European model of ETV set up and put to operation under the Pilot Programme of Environmental Technologies Verification of the European Union. The goal, objectives, technological scope, involved entities are presented. An attempt has been made to summarise the results of the EU ETV scheme performance available for the period of 2012 when the programme has become fully operational until the first half of 2016. The study was aimed at analysing the overall organisation and efficiency of the EU ETV Pilot Programme. The study was based on the analysis of the documents the operation of the EU ETV system. For this purpose, a relevant statistical analysis of the data on the performance of the EU ETV system provided by the European Commission was carried out.

Post-Fragmentation Whole Genome Amplification-Based Method

NASA Technical Reports Server (NTRS)

Benardini, James; LaDuc, Myron T.; Langmore, John

2011-01-01

This innovation is derived from a proprietary amplification scheme that is based upon random fragmentation of the genome into a series of short, overlapping templates. The resulting shorter DNA strands (<400 bp) constitute a library of DNA fragments with defined 3 and 5 termini. Specific primers to these termini are then used to isothermally amplify this library into potentially unlimited quantities that can be used immediately for multiple downstream applications including gel eletrophoresis, quantitative polymerase chain reaction (QPCR), comparative genomic hybridization microarray, SNP analysis, and sequencing. The standard reaction can be performed with minimal hands-on time, and can produce amplified DNA in as little as three hours. Post-fragmentation whole genome amplification-based technology provides a robust and accurate method of amplifying femtogram levels of starting material into microgram yields with no detectable allele bias. The amplified DNA also facilitates the preservation of samples (spacecraft samples) by amplifying scarce amounts of template DNA into microgram concentrations in just a few hours. Based on further optimization of this technology, this could be a feasible technology to use in sample preservation for potential future sample return missions. The research and technology development described here can be pivotal in dealing with backward/forward biological contamination from planetary missions. Such efforts rely heavily on an increasing understanding of the burden and diversity of microorganisms present on spacecraft surfaces throughout assembly and testing. The development and implementation of these technologies could significantly improve the comprehensiveness and resolving power of spacecraft-associated microbial population censuses, and are important to the continued evolution and advancement of planetary protection capabilities. Current molecular procedures for assaying spacecraft-associated microbial burden and diversity have inherent sample loss issues at practically every step, particularly nucleic acid extraction. In engineering a molecular means of amplifying nucleic acids directly from single cells in their native state within the sample matrix, this innovation has circumvented entirely the need for DNA extraction regimes in the sample processing scheme.

Innovation: Examining Workplace Learning in New Enterprises.

ERIC Educational Resources Information Center

Fenwick, Tara

2003-01-01

A study of women entrepreneurs explored learning in the process of business start-up, conditions that foster innovative learning (challenge/variety, compelling social purpose, recognition and pride), and forms of innovative learning (generating multiple ideas, scanning, optimizing, problem solving, self-confidence). Innovative processes involved…

Adoption of a High-Impact Innovation in a Homogeneous Population

NASA Astrophysics Data System (ADS)

Weiss, Curtis H.; Poncela-Casasnovas, Julia; Glaser, Joshua I.; Pah, Adam R.; Persell, Stephen D.; Baker, David W.; Wunderink, Richard G.; Nunes Amaral, Luís A.

2014-10-01

Adoption of innovations, whether new ideas, technologies, or products, is crucially important to knowledge societies. The landmark studies of adoption dealt with innovations having great societal impact (such as antibiotics or hybrid crops) but where determining the utility of the innovation was straightforward (such as fewer side effects or greater yield). Recent large-scale studies of adoption were conducted within heterogeneous populations and focused on products with little societal impact. Here, we focus on a case with great practical significance: adoption by small groups of highly trained individuals of innovations with large societal impact but for which it is impractical to determine the true utility of the innovation. Specifically, we study experimentally the adoption by critical care physicians of a diagnostic assay that complements current protocols for the diagnosis of life-threatening bacterial infections and for which a physician cannot estimate the true accuracy of the assay based on personal experience. We show through computational modeling of the experiment that infection-spreading models—which have been formalized as generalized contagion processes—are not consistent with the experimental data, while a model inspired by opinion models is able to reproduce the empirical data. Our modeling approach enables us to investigate the efficacy of different intervention schemes on the rate and robustness of innovation adoption in the real world. While our study is focused on critical care physicians, our findings have implications for other settings in education, research, and business, where small groups of highly qualified peers make decisions about the adoption of innovations whose utility is difficult if not impossible to gauge.

The UK Ecosystem for Fostering Innovation in the Earth & Space Sciences

NASA Astrophysics Data System (ADS)

Lee, V. E.

2015-12-01

The UK national government supports an ecosystem of government-funded organisations that carry a specific remit for innovation. By specifically cultivating the commercialisation of research where appropriate, the UK demonstrates a forward-thinking and coordinated approach to deriving economic and societal impact from scientific research activities. This presentation provides an overview of innovation activities at government-backed organisations that support the Earth and space science communities. At the broadest and highest levels, the UK has a whole-of-government approach to fostering innovation. The government also has a designated innovation agency - Innovate UK - which works with people, companies, and partner organisations to find and drive the science & technology innovations that will grow the UK economy. A primary source of scientific funding to UK-based researchers comes from the Research Councils UK (RCUK), which has seven constituent Research Councils. Along with funding activities that support basic research, innovation is supported through a variety of activities. The National Environmental Research Council (NERC), the UK's leading public funder for Earth & environmental science, has brought to market a wide variety of ideas and innovations, including by helping to register patents, negotiating licensing deals, and setting up spin-out companies or joint ventures with commercial organisations. Case studies of NERC commercialization successes will be given, as well as an overview of mechanisms by which NERC supports innovation. These include 'Pathfinder' awards that help enable researchers to develop a greater understanding of the commercial aspects and possibilities of their research. Complementary 'Follow-on Fund' awards provide proof-of-concept funding to support the commercialisation of ideas arising from NERC-funded research. Early-career researchers are also eligible for NERC's Environment Young Entrepreneurs Scheme. Innovation activity, like basic research, can be enhanced through international collaboration and engagement. Approaches taken by UK organisations such as RCUK seek to bring together the correct teams, regardless of nationality, to develop innovations needed to address common challenges.

NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

PubMed

Delaglio, F; Grzesiek, S; Vuister, G W; Zhu, G; Pfeifer, J; Bax, A

1995-11-01

The NMRPipe system is a UNIX software environment of processing, graphics, and analysis tools designed to meet current routine and research-oriented multidimensional processing requirements, and to anticipate and accommodate future demands and developments. The system is based on UNIX pipes, which allow programs running simultaneously to exchange streams of data under user control. In an NMRPipe processing scheme, a stream of spectral data flows through a pipeline of processing programs, each of which performs one component of the overall scheme, such as Fourier transformation or linear prediction. Complete multidimensional processing schemes are constructed as simple UNIX shell scripts. The processing modules themselves maintain and exploit accurate records of data sizes, detection modes, and calibration information in all dimensions, so that schemes can be constructed without the need to explicitly define or anticipate data sizes or storage details of real and imaginary channels during processing. The asynchronous pipeline scheme provides other substantial advantages, including high flexibility, favorable processing speeds, choice of both all-in-memory and disk-bound processing, easy adaptation to different data formats, simpler software development and maintenance, and the ability to distribute processing tasks on multi-CPU computers and computer networks.

What Does Innovation Mean for Moral Educators?

ERIC Educational Resources Information Center

Reiman, Alan J.; Dotger, Benjamin H.

2008-01-01

This article examines the links between prosocial moral education, educational innovations and concerns of school system personnel during an innovation's implementation process. The role of social innovations in promoting prosocial moral education is discussed with attention given to the challenges and processes associated with implementing such…

The Seductive Power of an Innovation: Enrolling Non-Conventional Actors in a Drip Irrigation Community in Morocco

ERIC Educational Resources Information Center

Benouniche, Maya; Errahj, Mostafa; Kuper, Marcel

2016-01-01

Purpose: The aim of this study was to analyze the motivations of non-conventional innovation actors to engage in innovation processes, how their involvement changed the technology and their own social-professional status, and to analyze their role in the diffusion of the innovation. Design/methodology/approach: We studied the innovation process of…

Software Defined Network Monitoring Scheme Using Spectral Graph Theory and Phantom Nodes

DTIC Science & Technology

2014-09-01

networks is the emergence of software - defined networking ( SDN ) [1]. SDN has existed for the...Chapter III for network monitoring. A. SOFTWARE DEFINED NETWORKS SDNs provide a new and innovative method to simplify network hardware by logically...and R. Giladi, “Performance analysis of software - defined networking ( SDN ),” in Proc. of IEEE 21st International Symposium on Modeling, Analysis

What Drives Failed Policy at the World Bank? An inside Account of New Aid Modalities to Higher Education: Context, Blame, and Infallibility

ERIC Educational Resources Information Center

Rappleye, Jeremy; Un, Leang

2018-01-01

This article analyses recent World Bank interventions aimed at improving higher education and local research capacity in low-income countries. Our empirical entry point is a critical analysis of the Development and Innovation Grant (DIG) scheme the Bank rolled out in Cambodia (2010-2015), a virtual carbon copy export of its Academic Initiative…

Teacher Incentive Pay and Educational Outcomes: Evidence from the NYC Bonus Program. Program on Education Policy and Governance Working Papers Series. PEPG 10-07

ERIC Educational Resources Information Center

Goodman, Sarena; Turner, Lesley

2010-01-01

Teacher compensation schemes are often criticized for lacking a performance-based component. Proponents of merit pay argue that linking teacher salaries to student achievement will incentivize teachers to focus on raising student achievement and stimulate innovation across the school system as a whole. In this paper, we utilize a policy experiment…

Corporate Associate Partnerships: Practitioners' Involvement in the Delivery of an Auditing Course Based on a Case-Study: A Teaching Resource

ERIC Educational Resources Information Center

Slack, Richard; Loughran, Jan; Abrahams, Kirsty

2014-01-01

This Teaching Resource outlines and reflects upon the use of an innovative corporate associate partnership scheme as part of the delivery of an Auditing course to final year undergraduate Accounting students at a university in the UK. It outlines the motivations behind a practitioner's involvement in teaching delivery, along with the formulation,…

Canadian cardiac surgeons' perspectives on biomedical innovation.

PubMed

Snyman, Gretchen; Tucker, Joseph E L; Cimini, Massimo; Narine, Kishan; Fedak, Paul W M

2012-01-01

Barriers to successful innovation can be identified and potentially addressed by exploring the perspectives of key stakeholders in the innovation process. Cardiac surgeons in Canada were surveyed for personal perspectives on biomedical innovation. Quantitative data was obtained by questionnaire and qualitative data via interviews with selected survey participants. Surgeons were asked to self-identify into 1 of 3 categories: "innovator," "early adopter," or "late adopter," and data were compared between groups. Most surgeons viewed innovation favourably and this effect was consistent irrespective of perceived level of innovativeness. Key barriers to the innovation pathway were identified: (1) support from colleagues and institutions; (2) Canada's health system; (3) sufficient investment capital; and (4) the culture of innovation within the local environment. Knowledge of the innovation process was perceived differently based on self-reported innovativeness. The majority of surgeons did not perceive themselves as having the necessary knowledge and skills to effectively translate innovative ideas to clinical practice. In general, responses indicate support for implementation of leadership and training programs focusing on the innovation process in an effort to prepare surgeons and enhance their ability to successfully innovate and translate new therapies. The perspectives of cardiac surgeons provide an intriguing portal into the challenges and opportunities for healthcare innovation in Canada. Copyright © 2012 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

36 CFR 72.53 - Preapplication process for Rehabilitation and Innovation grants.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Rehabilitation and Innovation grants. 72.53 Section 72.53 Parks, Forests, and Public Property NATIONAL PARK..., Approval and Administration § 72.53 Preapplication process for Rehabilitation and Innovation grants. To... to submission and approval of Rehabilitation and Innovation proposals. (1) Preapplications shall be...

36 CFR 72.53 - Preapplication process for Rehabilitation and Innovation grants.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Rehabilitation and Innovation grants. 72.53 Section 72.53 Parks, Forests, and Public Property NATIONAL PARK..., Approval and Administration § 72.53 Preapplication process for Rehabilitation and Innovation grants. To... to submission and approval of Rehabilitation and Innovation proposals. (1) Preapplications shall be...

36 CFR 72.53 - Preapplication process for Rehabilitation and Innovation grants.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Rehabilitation and Innovation grants. 72.53 Section 72.53 Parks, Forests, and Public Property NATIONAL PARK..., Approval and Administration § 72.53 Preapplication process for Rehabilitation and Innovation grants. To... to submission and approval of Rehabilitation and Innovation proposals. (1) Preapplications shall be...

36 CFR 72.53 - Preapplication process for Rehabilitation and Innovation grants.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Rehabilitation and Innovation grants. 72.53 Section 72.53 Parks, Forests, and Public Property NATIONAL PARK..., Approval and Administration § 72.53 Preapplication process for Rehabilitation and Innovation grants. To... to submission and approval of Rehabilitation and Innovation proposals. (1) Preapplications shall be...

36 CFR 72.53 - Preapplication process for Rehabilitation and Innovation grants.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Rehabilitation and Innovation grants. 72.53 Section 72.53 Parks, Forests, and Public Property NATIONAL PARK..., Approval and Administration § 72.53 Preapplication process for Rehabilitation and Innovation grants. To... to submission and approval of Rehabilitation and Innovation proposals. (1) Preapplications shall be...

Optimization of wastewater treatment alternative selection by hierarchy grey relational analysis.

PubMed

Zeng, Guangming; Jiang, Ru; Huang, Guohe; Xu, Min; Li, Jianbing

2007-01-01

This paper describes an innovative systematic approach, namely hierarchy grey relational analysis for optimal selection of wastewater treatment alternatives, based on the application of analytic hierarchy process (AHP) and grey relational analysis (GRA). It can be applied for complicated multicriteria decision-making to obtain scientific and reasonable results. The effectiveness of this approach was verified through a real case study. Four wastewater treatment alternatives (A(2)/O, triple oxidation ditch, anaerobic single oxidation ditch and SBR) were evaluated and compared against multiple economic, technical and administrative performance criteria, including capital cost, operation and maintenance (O and M) cost, land area, removal of nitrogenous and phosphorous pollutants, sludge disposal effect, stability of plant operation, maturity of technology and professional skills required for O and M. The result illustrated that the anaerobic single oxidation ditch was the optimal scheme and would obtain the maximum general benefits for the wastewater treatment plant to be constructed.

Recent Advances for the Detection of Ochratoxin A.

PubMed

Ha, Tai Hwan

2015-12-04

Ochratoxin A (OTA) is one of the mycotoxins secreted by Aspersillus and Penicillium that can easily colonize various grains like coffee, peanut, rice, and maize. Since OTA is a chemically stable compound that can endure the physicochemical conditions of modern food processing, additional research efforts have been devoted to develop sensitive and cost-effective surveillance solutions. Although traditional chromatographic and immunoassays appear to be mature enough to attain sensitivity up to the regulation levels, alternative detection schemes are still being enthusiastically pursued in an attempt to meet the requirements of rapid and cost-effective detections. Herein, this review presents recent progresses in OTA detections with minimal instrumental usage, which have been facilitated by the development of OTA aptamers and by the innovations in functional nanomaterials. In addition to the introduction of aptamer-based OTA detection techniques, OTA-specific detection principles are also presented, which exclusively take advantage of the unique chemical structure and related physicochemical characteristics.

Weighted stacking of seismic AVO data using hybrid AB semblance and local similarity

NASA Astrophysics Data System (ADS)

Deng, Pan; Chen, Yangkang; Zhang, Yu; Zhou, Hua-Wei

2016-04-01

The common-midpoint (CMP) stacking technique plays an important role in enhancing the signal-to-noise ratio (SNR) in seismic data processing and imaging. Weighted stacking is often used to improve the performance of conventional equal-weight stacking in further attenuating random noise and handling the amplitude variations in real seismic data. In this study, we propose to use a hybrid framework of combining AB semblance and a local-similarity-weighted stacking scheme. The objective is to achieve an optimal stacking of the CMP gathers with class II amplitude-variation-with-offset (AVO) polarity-reversal anomaly. The selection of high-quality near-offset reference trace is another innovation of this work because of its better preservation of useful energy. Applications to synthetic and field seismic data demonstrate a great improvement using our method to capture the true locations of weak reflections, distinguish thin-bed tuning artifacts, and effectively attenuate random noise.

Loop optimization for tensor network renormalization

NASA Astrophysics Data System (ADS)

Yang, Shuo; Gu, Zheng-Cheng; Wen, Xiao-Gang

We introduce a tensor renormalization group scheme for coarse-graining a two-dimensional tensor network, which can be successfully applied to both classical and quantum systems on and off criticality. The key idea of our scheme is to deform a 2D tensor network into small loops and then optimize tensors on each loop. In this way we remove short-range entanglement at each iteration step, and significantly improve the accuracy and stability of the renormalization flow. We demonstrate our algorithm in the classical Ising model and a frustrated 2D quantum model. NSF Grant No. DMR-1005541 and NSFC 11274192, BMO Financial Group, John Templeton Foundation, Government of Canada through Industry Canada, Province of Ontario through the Ministry of Economic Development & Innovation.

Map templates in a European Research program: emerging consensus, without compromising cartographic innovation

NASA Astrophysics Data System (ADS)

Zanin, Christine; Ysebaert, Ronan

2018-05-01

Maps are produced to represent geography and spatial organization of natural or human features. They deliver spatial forms where each graphic object have its influence and can change the perceived message. The cartographic realization participates to the geographical analyzes and helps their memorization. Adding innovation to this achievement ensures a perception and understanding of the scientific information delivered. The question is to understand what innovation is, when we speak about cartography. The underpinnings of the design and delivery of these representations are surely linked to developments in theory and technology applied to the geosciences, but not only. The purpose of this paper is to offer some ideas on the influence of an institutional framework on innovation and the relevance of a cartographic realization. Based on the example of the cartographic models construction in the framework of the research projects financed by the ESPON (European Observation Network for Territorial Development and Cohesion) Programme, we try to show how a framework that is too strict and fixed upstream of cartographic design can lead to a homogeneous and stereotyped production, without innovation or simply cartographic originality. In conclusion, we show how a close negotiation between funders and cartographers can help to evolve the cartographic scheme in place. Several proposals are put forward.

36 CFR 72.54 - Rehabilitation and Innovation grants-full application process.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Rehabilitation and Innovation..., Approval and Administration § 72.54 Rehabilitation and Innovation grants—full application process. Once a Rehabilitation or Innovation proposal has received a tentative grant offer, applicants will be responsible for...

36 CFR 72.54 - Rehabilitation and Innovation grants-full application process.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Rehabilitation and Innovation..., Approval and Administration § 72.54 Rehabilitation and Innovation grants—full application process. Once a Rehabilitation or Innovation proposal has received a tentative grant offer, applicants will be responsible for...

36 CFR 72.54 - Rehabilitation and Innovation grants-full application process.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Rehabilitation and Innovation..., Approval and Administration § 72.54 Rehabilitation and Innovation grants—full application process. Once a Rehabilitation or Innovation proposal has received a tentative grant offer, applicants will be responsible for...

36 CFR 72.54 - Rehabilitation and Innovation grants-full application process.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Rehabilitation and Innovation..., Approval and Administration § 72.54 Rehabilitation and Innovation grants—full application process. Once a Rehabilitation or Innovation proposal has received a tentative grant offer, applicants will be responsible for...

36 CFR 72.54 - Rehabilitation and Innovation grants-full application process.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Rehabilitation and Innovation..., Approval and Administration § 72.54 Rehabilitation and Innovation grants—full application process. Once a Rehabilitation or Innovation proposal has received a tentative grant offer, applicants will be responsible for...

Overview of the Meso-NH model version 5.4 and its applications

NASA Astrophysics Data System (ADS)

Lac, Christine; Chaboureau, Jean-Pierre; Masson, Valéry; Pinty, Jean-Pierre; Tulet, Pierre; Escobar, Juan; Leriche, Maud; Barthe, Christelle; Aouizerats, Benjamin; Augros, Clotilde; Aumond, Pierre; Auguste, Franck; Bechtold, Peter; Berthet, Sarah; Bielli, Soline; Bosseur, Frédéric; Caumont, Olivier; Cohard, Jean-Martial; Colin, Jeanne; Couvreux, Fleur; Cuxart, Joan; Delautier, Gaëlle; Dauhut, Thibaut; Ducrocq, Véronique; Filippi, Jean-Baptiste; Gazen, Didier; Geoffroy, Olivier; Gheusi, François; Honnert, Rachel; Lafore, Jean-Philippe; Lebeaupin Brossier, Cindy; Libois, Quentin; Lunet, Thibaut; Mari, Céline; Maric, Tomislav; Mascart, Patrick; Mogé, Maxime; Molinié, Gilles; Nuissier, Olivier; Pantillon, Florian; Peyrillé, Philippe; Pergaud, Julien; Perraud, Emilie; Pianezze, Joris; Redelsperger, Jean-Luc; Ricard, Didier; Richard, Evelyne; Riette, Sébastien; Rodier, Quentin; Schoetter, Robert; Seyfried, Léo; Stein, Joël; Suhre, Karsten; Taufour, Marie; Thouron, Odile; Turner, Sandra; Verrelle, Antoine; Vié, Benoît; Visentin, Florian; Vionnet, Vincent; Wautelet, Philippe

2018-05-01

This paper presents the Meso-NH model version 5.4. Meso-NH is an atmospheric non hydrostatic research model that is applied to a broad range of resolutions, from synoptic to turbulent scales, and is designed for studies of physics and chemistry. It is a limited-area model employing advanced numerical techniques, including monotonic advection schemes for scalar transport and fourth-order centered or odd-order WENO advection schemes for momentum. The model includes state-of-the-art physics parameterization schemes that are important to represent convective-scale phenomena and turbulent eddies, as well as flows at larger scales. In addition, Meso-NH has been expanded to provide capabilities for a range of Earth system prediction applications such as chemistry and aerosols, electricity and lightning, hydrology, wildland fires, volcanic eruptions, and cyclones with ocean coupling. Here, we present the main innovations to the dynamics and physics of the code since the pioneer paper of Lafore et al. (1998) and provide an overview of recent applications and couplings.

Clustering-based energy-saving algorithm in ultra-dense network

NASA Astrophysics Data System (ADS)

Huang, Junwei; Zhou, Pengguang; Teng, Deyang; Zhang, Renchi; Xu, Hao

2017-06-01

In Ultra-dense Networks (UDN), dense deployment of low power small base stations will cause serious small cells interference and a large amount of energy consumption. The purpose of this paper is to explore the method of reducing small cells interference and energy saving system in UDN, and we innovatively propose a sleep-waking-active (SWA) scheme. The scheme decreases the user outage causing by failure to detect users’ service requests, shortens the opening time of active base stations directly switching to sleep mode; we further proposes a Vertex Surrounding Clustering(VSC) algorithm, which first colours the small cells with the most strongest interference and next extends to the adjacent small cells. VSC algorithm can use the least colour to stain the small cell, reduce the number of iterations and promote the efficiency of colouring. The simulation results show that SWA scheme can effectively improve the system Energy Efficiency (EE), the VSC algorithm can reduce the small cells interference and optimize the users’ Spectrum Efficiency (SE) and throughput.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elia, Valerio; Gnoni, Maria Grazia, E-mail: mariagrazia.gnoni@unisalento.it; Tornese, Fabiana

Highlights: • Pay-As-You-Throw (PAYT) schemes are becoming widespread in several countries. • Economic, organizational and technological issues have to be integrated in an efficient PAYT model design. • Efficiency refers to a PAYT system which support high citizen participation rates as well as economic sustainability. • Different steps and constraints have to be evaluated from collection services to type technologies. • An holistic approach is discussed to support PAYT systems diffusion. - Abstract: Pay-As-You-Throw (PAYT) strategies are becoming widely applied in solid waste management systems; the main purpose is to support a more sustainable – from economic, environmental and socialmore » points of view – management of waste flows. Adopting PAYT charging models increases the complexity level of the waste management service as new organizational issues have to be evaluated compared to flat charging models. In addition, innovative technological solutions could also be adopted to increase the overall efficiency of the service. Unit pricing, user identification and waste measurement represent the three most important processes to be defined in a PAYT system. The paper proposes a holistic framework to support an effective design and management process. The framework defines most critical processes and effective organizational and technological solutions for supporting waste managers as well as researchers.« less

Resource Management Scheme Based on Ubiquitous Data Analysis

PubMed Central

Lee, Heung Ki; Jung, Jaehee

2014-01-01

Resource management of the main memory and process handler is critical to enhancing the system performance of a web server. Owing to the transaction delay time that affects incoming requests from web clients, web server systems utilize several web processes to anticipate future requests. This procedure is able to decrease the web generation time because there are enough processes to handle the incoming requests from web browsers. However, inefficient process management results in low service quality for the web server system. Proper pregenerated process mechanisms are required for dealing with the clients' requests. Unfortunately, it is difficult to predict how many requests a web server system is going to receive. If a web server system builds too many web processes, it wastes a considerable amount of memory space, and thus performance is reduced. We propose an adaptive web process manager scheme based on the analysis of web log mining. In the proposed scheme, the number of web processes is controlled through prediction of incoming requests, and accordingly, the web process management scheme consumes the least possible web transaction resources. In experiments, real web trace data were used to prove the improved performance of the proposed scheme. PMID:25197692

User roles and contributions during the new product development process in collaborative innovation communities.

PubMed

Guo, Wei; Zheng, Qing; An, Weijin; Peng, Wei

2017-09-01

Collaborative innovation (co-innovation) community emerges as a new product design platform where companies involve users in the new product development (NPD) process. Large numbers of users participate and contribute to the process voluntarily. This exploratory study investigates the heterogeneous roles of users based on a global co-innovation project in online community. Content analysis, social network analysis and cluster method are employed to measure user behaviors, distinguish user roles, and analyze user contributions. The study identifies six user roles that emerge during the NPD process in co-innovation community: project leader, active designer, generalist, communicator, passive designer, and observer. The six user roles differ in their contribution forms and quality. This paper contributes to research on co-innovation in online communities, including design team structure, user roles and their contribution to design task and solution, as well as user value along the process. In addition, the study provides practices guidance on implementing project, attracting users, and designing platform for co-innovation community practitioners. Copyright © 2017 Elsevier Ltd. All rights reserved.

Parallel discrete-event simulation schemes with heterogeneous processing elements.

PubMed

Kim, Yup; Kwon, Ikhyun; Chae, Huiseung; Yook, Soon-Hyung

2014-07-01

To understand the effects of nonidentical processing elements (PEs) on parallel discrete-event simulation (PDES) schemes, two stochastic growth models, the restricted solid-on-solid (RSOS) model and the Family model, are investigated by simulations. The RSOS model is the model for the PDES scheme governed by the Kardar-Parisi-Zhang equation (KPZ scheme). The Family model is the model for the scheme governed by the Edwards-Wilkinson equation (EW scheme). Two kinds of distributions for nonidentical PEs are considered. In the first kind computing capacities of PEs are not much different, whereas in the second kind the capacities are extremely widespread. The KPZ scheme on the complex networks shows the synchronizability and scalability regardless of the kinds of PEs. The EW scheme never shows the synchronizability for the random configuration of PEs of the first kind. However, by regularizing the arrangement of PEs of the first kind, the EW scheme is made to show the synchronizability. In contrast, EW scheme never shows the synchronizability for any configuration of PEs of the second kind.

Innovative model of business process reengineering at machine building enterprises

NASA Astrophysics Data System (ADS)

Nekrasov, R. Yu; Tempel, Yu A.; Tempel, O. A.

2017-10-01

The paper provides consideration of business process reengineering viewed as amanagerial innovation accepted by present day machine building enterprises, as well as waysto improve its procedure. A developed innovative model of reengineering measures isdescribed and is based on the process approach and other principles of company management.

New norms new policies: Did the Adelaide Thinkers in Residence scheme encourage new thinking about promoting well-being and Health in All Policies?

PubMed

Baum, Fran; Lawless, Angela; MacDougall, Colin; Delany, Toni; McDermott, Dennis; Harris, Elizabeth; Williams, Carmel

2015-12-01

Health systems have long been criticised for focussing on curing rather than preventing disease. This paper examines to what extent the Adelaide Thinkers in Residence (ATiR) scheme contributed to the change in norms whereby promoting well-being and a strategy to achieve this - Health in All Policies (HiAP)--was adopted by the South Australian (SA) State Government from 2007. The data presented in this paper are drawn from a five year (2012-2016) detailed mixed methods case study of the SA HiAP initiative which involved document analysis, interviews and workshops with public servants and political actors. We adapt the framework used by Finnemore and Sikkink (1998) which explains how norm changes can lead to political changes in international affairs. We also use Kingdon's concept of policy entrepreneurs to determine whether these ideas moved to an implementable initiative with the help of both a specific ATiR program on HiAP and the broader TiR scheme which promoted a series of innovations relevant to health. The process involved the ATiR reinforcing the work of local norm entrepreneurs with that of powerful external policy entrepreneurs, adapting the discourse about the value of prevention and promoting well-being so that it fitted with the dominant economic one. The powerful organisational platform of the ATiR, which was under the Department of the Premier and Cabinet and linked to the South Australian Strategic Plan (SASP) was used to advance these ideas. The case study offers important lessons for other jurisdictions on how to shift policy to encourage intersectoral approaches to health. Copyright © 2015 Elsevier Ltd. All rights reserved.

Cognitive Design for Learning: Cognition and Emotion in the Design Process

ERIC Educational Resources Information Center

Hasebrook, Joachim

2016-01-01

We are so used to accept new technologies being the driver of change and innovation in human computer interfaces (HCI). In our research we focus on the development of innovations as a design process--or design, for short. We also refer to the entire process of creating innovations and putting them to use as "cognitive processes"--or…

Analysing barriers to service improvement using a multi-level theory of innovation: the case of glaucoma outpatient clinics.

PubMed

Turner, Simon; Vasilakis, Christos; Utley, Martin; Foster, Paul; Kotecha, Aachal; Fulop, Naomi J

2018-05-01

The development and implementation of innovation by healthcare providers is understood as a multi-determinant and multi-level process. Theories at different analytical levels (i.e. micro and organisational) are needed to capture the processes that influence innovation by providers. This article combines a micro theory of innovation, actor-network theory, with organisational level processes using the 'resource based view of the firm'. It examines the influence of, and interplay between, innovation-seeking teams (micro) and underlying organisational capabilities (meso) during innovation processes. We used ethnographic methods to study service innovations in relation to ophthalmology services run by a specialist English NHS Trust at multiple locations. Operational research techniques were used to support the ethnographic methods by mapping the care process in the existing and redesigned clinics. Deficiencies in organisational capabilities for supporting innovation were identified, including manager-clinician relations and organisation-wide resources. The article concludes that actor-network theory can be combined with the resource-based view to highlight the influence of organisational capabilities on the management of innovation. Equally, actor-network theory helps to address the lack of theory in the resource-based view on the micro practices of implementing change. © 2018 The Authors. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL.

Application of Improved 5th-Cubature Kalman Filter in Initial Strapdown Inertial Navigation System Alignment for Large Misalignment Angles

PubMed Central

Wang, Wei; Chen, Xiyuan

2018-01-01

In view of the fact the accuracy of the third-degree Cubature Kalman Filter (CKF) used for initial alignment under large misalignment angle conditions is insufficient, an improved fifth-degree CKF algorithm is proposed in this paper. In order to make full use of the innovation on filtering, the innovation covariance matrix is calculated recursively by an innovative sequence with an exponent fading factor. Then a new adaptive error covariance matrix scaling algorithm is proposed. The Singular Value Decomposition (SVD) method is used for improving the numerical stability of the fifth-degree CKF in this paper. In order to avoid the overshoot caused by excessive scaling of error covariance matrix during the convergence stage, the scaling scheme is terminated when the gradient of azimuth reaches the maximum. The experimental results show that the improved algorithm has better alignment accuracy with large misalignment angles than the traditional algorithm. PMID:29473912

Example of International Co-Operation in the Frame of the Project Phare (TEMPUS) in Innovations in Teaching of Environmental Hydrogeology in Engineering Education in the Czech Republic.

ERIC Educational Resources Information Center

Grmela, Arnost; Rapantova, Nadia

The international TEMPUS (Trans-European Co-operating and Mobility Scheme for Higher Education between Central/Eastern Europe and European Union) project lasted from 1995-1997. In the framework of TEMPUS, a material and knowledge background was developed in order to ensure the education of the branch Geological Engineering with specialization in…

Design, implementation, and evaluation of a community financing scheme for hospital care in developing countries: a pre-paid health plan in the Bwamanda health zone, Zaire.

PubMed

Moens, F

1990-01-01

Unless scarce resources can be mobilized and used efficiently, health for all by the year 2000 will remain a vain attempt. Innovative financing schemes exploring increased cost recovery from the users of the health system are explored throughout the world. In Bwamanda, Zaire, a community financing scheme for hospital care was developed through the application of operations research. A preference heuristic with considerable involvement of health providers and the community was used to identify the type of financing scheme and resulted in a pre-paid health plan, while a mathematical model was developed to determine the premiums to charge. The implementation of the health plant is briefly described. An evaluation of the effects of the pre-paid plan on the accessibility and equity of health care, as well as on the financial sustainability of the hospital, is presented and discussed: a steadily increasing membership of the health plan illustrates its appropriateness, while a doubling of the cost recovery of the hospital's operating costs after two years seems promising; the hospitalization rate of members of the health plan was significantly higher than for non-members. These findings suggest that a health zone may be an appropriate level for the organization of a regional pre-paid health plan. Problems of equity, full cost recovery, and replicability of the financing scheme are discussed.

Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation

PubMed Central

Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

2015-01-01

Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. PMID:26574523

Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation.

PubMed

Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

2015-12-28

Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. © 2015 The Authors.

Interferometry-based free space communication and information processing

NASA Astrophysics Data System (ADS)

Arain, Muzammil Arshad

This dissertation studies, analyzes, and experimentally demonstrates the innovative use of interference phenomenon in the field of opto-electronic information processing and optical communications. A number of optical systems using interferometric techniques both in the optical and the electronic domains has been demonstrated in the filed of signal transmission and processing, optical metrology, defense, and physical sensors. Specifically it has been shown that the interference of waves in the form of holography can be exploited to realize a novel optical scanner called Code Multiplexed Optical Scanner (C-MOS). The C-MOS features large aperture, wide scan angles, 3-D beam control, no moving parts, and high beam scanning resolution. A C-MOS based free space optical transceiver for bi-directional communication has also been experimentally demonstrated. For high speed, large bandwidth, and high frequency operation, an optically implemented reconfigurable RF transversal filter design is presented that implements wide range of filtering algorithms. A number of techniques using heterodyne interferometry via acousto-optic device for optical path length measurements have been described. Finally, a whole new class of interferometric sensors for optical metrology and sensing applications is presented. A non-traditional interferometric output signal processing scheme has been developed. Applications include, for example, temperature sensors for harsh environments for a wide temperature range from room temperature to 1000°C.

The democratization of health in Mexico: financial innovations for universal coverage

PubMed Central

Frenk, Julio; Knaul, Felicia Marie

2009-01-01

Abstract In 2003, the Mexican Congress approved a reform establishing the Sistema de Protección Social en Salud [System of Social Protection in Health], whereby public funding for health is being increased by one percent of the 2003 gross domestic product over seven years to guarantee universal health insurance. Poor families that had been excluded from traditional social security can now enrol in a new public insurance scheme known as Seguro Popular [People’s Insurance], which assures legislated access to a comprehensive set of health-care entitlements. This paper describes the financial innovations behind the expansion of health-care coverage in Mexico to everyone and their effects. Evidence shows improvements in mobilization of additional public resources; availability of health infrastructure and drugs; service utilization; effective coverage; and financial protection. Future challenges are discussed, among them the need for additional public funding to extend access to costly interventions for non-communicable diseases not yet covered by the new insurance scheme, and to improve the technical quality of care and the responsiveness of the health system. Eventually, the progress achieved so far will have to be reflected in health outcomes, which will continue to be evaluated so that Mexico can meet the ultimate criterion of reform success: better health through equity, quality and fair financing. PMID:19649369

The democratization of health in Mexico: financial innovations for universal coverage.

PubMed

Frenk, Julio; Gómez-Dantés, Octavio; Knaul, Felicia Marie

2009-07-01

In 2003, the Mexican Congress approved a reform establishing the Sistema de Protección Social en Salud [System of Social Protection in Health], whereby public funding for health is being increased by one percent of the 2003 gross domestic product over seven years to guarantee universal health insurance. Poor families that had been excluded from traditional social security can now enrol in a new public insurance scheme known as Seguro Popular [People's Insurance], which assures legislated access to a comprehensive set of health-care entitlements. This paper describes the financial innovations behind the expansion of health-care coverage in Mexico to everyone and their effects. Evidence shows improvements in mobilization of additional public resources; availability of health infrastructure and drugs; service utilization; effective coverage; and financial protection. Future challenges are discussed, among them the need for additional public funding to extend access to costly interventions for non-communicable diseases not yet covered by the new insurance scheme, and to improve the technical quality of care and the responsiveness of the health system. Eventually, the progress achieved so far will have to be reflected in health outcomes, which will continue to be evaluated so that Mexico can meet the ultimate criterion of reform success: better health through equity, quality and fair financing.

The constitutional protection of trade secrets and patents under the Biologics Price Competition and Innovation Act of 2009.

PubMed

Epstein, Richard A

2011-01-01

The Biologics Price Competition and Innovation Act of 2009 ("Biosimilars Act") is for the field of pharmaceutical products the single most important legislative development since passage of the Drug Price Competition and Patent Term Restoration Act of 1984 ("Hatch-Waxman Act"), on which portions of the Biosimilars Act are clearly patterned. Congress revised section 351 of the Public Health Service Act (PHSA) to create a pathway for FDA approval of "biosimilar" biological products. Each biosimilar applicant is required to cite in its application a "reference product" that was approved on the basis of a full application containing testing data and manufacturing information, which is owned and was submitted by another company and much of which constitutes trade secret information subject to constitutional protection. Because the Biosimilars Act authorizes biosimilar applicants to cite these previously approved applications, the implementation of the new legislative scheme raises critical issues under the Fifth Amendment of the Constitution, pursuant to which private property--trade secrets included--may not be taken for public use, without "just compensation." FDA must confront those issues as it implements the scheme set out in the Biosimilars Act. This article will discuss these issues, after providing a brief overview of the Biosimilars Act and a more detailed examination of the law of trade secrets.

Open the `black box' creativity and innovation: a study of activities in R&D departments. Some prospects for engineering education

NASA Astrophysics Data System (ADS)

Millet, Charlyne; Oget, David; Cavallucci, Denis

2017-11-01

Innovation is a key component to the success and longevity of companies. Our research opens the 'black box' of creativity and innovation in R&D teams. We argue that understanding the nature of R&D projects in terms of creativity/innovation, efficiency/inefficiency, is important for designing education policies and improving engineering curriculum. Our research addresses the inventive design process, a lesser known aspect of the innovation process, in 197 R&D departments of industrial sector companies in France. One fundamental issue facing companies is to evaluate processes and results of innovation. Results show that the evaluation of innovation is confined by a lack of methodology of inventive projects. We will be establishing the foundations of a formal ontology for inventive design projects and finally some recommendations for engineering education.

WHAT ARE INNOVATORS LIKE. CHAPTER 4, CHANGE PROCESSES IN THE PUBLIC SCHOOLS.

ERIC Educational Resources Information Center

ROGERS, EVERETT M.

CHARACTERISTICS OF INNOVATORS ARE DISCUSSED WITH SPECIAL REFERENCE TO THE PROCESS OF SOCIAL CHANGE. ABOUT 2.5 PERCENT OF THE EDUCATIONAL ADMINISTRATORS TEND TO BE INNOVATORS. SIX GENERAL CHARACTERISTICS OF INNOVATORS ARE LISTED--(1) THEY ARE GENERALLY YOUNG, (2) THEY HAVE RELATIVELY HIGH SOCIAL STATUS IN TERMS OF AMOUNT OF EDUCATION, PRESTIGE…

Innovation and design approaches within prospective ergonomics.

PubMed

Liem, André; Brangier, Eric

2012-01-01

In this conceptual article the topic of "Prospective Ergonomics" will be discussed within the context of innovation, design thinking and design processes & methods. Design thinking is essentially a human-centred innovation process that emphasises observation, collaboration, interpretation, visualisation of ideas, rapid concept prototyping and concurrent business analysis, which ultimately influences innovation and business strategy. The objective of this project is to develop a roadmap for innovation, involving consumers, designers and business people in an integrative process, which can be applied to product, service and business design. A theoretical structure comprising of Innovation perspectives (1), Worldviews supported by rationalist-historicist and empirical-idealistic dimensions (2) and Models of "design" reasoning (3) precedes the development and classification of existing methods as well as the introduction of new ones.

Innovation in Health Care Delivery.

PubMed

Sharan, Alok D; Schroeder, Gregory D; West, Michael E; Vaccaro, Alexander R

2016-02-01

As reimbursement transitions from a volume-based to a value-based system, innovation in health care delivery will be needed. The process of innovation begins with framing the problem that needs to be solved along with the strategic vision that has to be achieved. Similar to scientific testing, a hypothesis is generated for a new solution to a problem. Innovation requires conducting a disciplined form of experimentation and then learning from the process. This manuscript will discuss the different types of innovation, and the key steps necessary for successful innovation in the health care field.

The Evolutionary Process of Secondary Innovation in the Context of Globalization: A Case Study

ERIC Educational Resources Information Center

Wu, Xiaobo; Xu, Guannan; Ma, Rufei; Du, Jian

2008-01-01

This paper examines the evolutionary process of secondary innovation in a typical Chinese equipment manufacturing firm in the context of globalization and elaborates how to achieve latecomer's advantage from imitation to innovation. Four stages are identified in the process of international manufacturing: the equipment import stage, the production…

Mapping knowledge translation and innovation processes in Cancer Drug Development: the case of liposomal doxorubicin.

PubMed

Fajardo-Ortiz, David; Duran, Luis; Moreno, Laura; Ochoa, Hector; Castaño, Victor M

2014-09-03

We explored how the knowledge translation and innovation processes are structured when theyresult in innovations, as in the case of liposomal doxorubicin research. In order to map the processes, a literature network analysis was made through Cytoscape and semantic analysis was performed by GOPubmed which is based in the controlled vocabularies MeSH (Medical Subject Headings) and GO (Gene Ontology). We found clusters related to different stages of the technological development (invention, innovation and imitation) and the knowledge translation process (preclinical, translational and clinical research), and we were able to map the historic emergence of Doxil as a paradigmatic nanodrug. This research could be a powerful methodological tool for decision-making and innovation management in drug delivery research.

Laboratory Innovation Towards Quality Program Sustainability.

PubMed

Abimiku, Alash'le; Timperi, Ralph; Blattner, William

2016-08-01

Laboratory innovation significantly affects program sustainability of HIV programs in low and middle income countries (LMICs) far beyond its immediate sphere of impact. Innovation in rapid development of diagnostic technologies, improved quality management systems, strengthened laboratory management, affordable external quality assurance and accreditation schemes, and building local capacity have reduced costs, brought quality improvement to point-of-care testing, increased access to testing services, reduced treatment and prevention costs and opened the door to the real possibility of ending the AIDS epidemic. However, for effectively implemented laboratory innovation to contribute to HIV quality program sustainability, it must be implemented within the overall context of the national strategic plan and HIV treatment programs. The high quality of HIV rapid diagnostic test was a breakthrough that made it possible for more persons to learn their HIV status, receive counseling, and if infected to receive treatment. Likewise, the use of dried blood spots made the shipment of samples easier for the assessment of different variables of HIV infection-molecular diagnosis, CD4+ cell counts, HIV antibodies, drug resistance surveillance, and even antiretroviral drug level measurements. Such advancement is critical for to reaching the UNAIDS target of 90-90-90 and for bringing the AIDS epidemic to an end, especially in LMICs.

LDPC-PPM Coding Scheme for Optical Communication

NASA Technical Reports Server (NTRS)

Barsoum, Maged; Moision, Bruce; Divsalar, Dariush; Fitz, Michael

2009-01-01

In a proposed coding-and-modulation/demodulation-and-decoding scheme for a free-space optical communication system, an error-correcting code of the low-density parity-check (LDPC) type would be concatenated with a modulation code that consists of a mapping of bits to pulse-position-modulation (PPM) symbols. Hence, the scheme is denoted LDPC-PPM. This scheme could be considered a competitor of a related prior scheme in which an outer convolutional error-correcting code is concatenated with an interleaving operation, a bit-accumulation operation, and a PPM inner code. Both the prior and present schemes can be characterized as serially concatenated pulse-position modulation (SCPPM) coding schemes. Figure 1 represents a free-space optical communication system based on either the present LDPC-PPM scheme or the prior SCPPM scheme. At the transmitting terminal, the original data (u) are processed by an encoder into blocks of bits (a), and the encoded data are mapped to PPM of an optical signal (c). For the purpose of design and analysis, the optical channel in which the PPM signal propagates is modeled as a Poisson point process. At the receiving terminal, the arriving optical signal (y) is demodulated to obtain an estimate (a^) of the coded data, which is then processed by a decoder to obtain an estimate (u^) of the original data.

Design of an extensive information representation scheme for clinical narratives.

PubMed

Deléger, Louise; Campillos, Leonardo; Ligozat, Anne-Laure; Névéol, Aurélie

2017-09-11

Knowledge representation frameworks are essential to the understanding of complex biomedical processes, and to the analysis of biomedical texts that describe them. Combined with natural language processing (NLP), they have the potential to contribute to retrospective studies by unlocking important phenotyping information contained in the narrative content of electronic health records (EHRs). This work aims to develop an extensive information representation scheme for clinical information contained in EHR narratives, and to support secondary use of EHR narrative data to answer clinical questions. We review recent work that proposed information representation schemes and applied them to the analysis of clinical narratives. We then propose a unifying scheme that supports the extraction of information to address a large variety of clinical questions. We devised a new information representation scheme for clinical narratives that comprises 13 entities, 11 attributes and 37 relations. The associated annotation guidelines can be used to consistently apply the scheme to clinical narratives and are https://cabernet.limsi.fr/annotation_guide_for_the_merlot_french_clinical_corpus-Sept2016.pdf . The information scheme includes many elements of the major schemes described in the clinical natural language processing literature, as well as a uniquely detailed set of relations.

Open innovation at the Abbe School of Photonics

NASA Astrophysics Data System (ADS)

Helgert, Christian; Geiss, Reinhard; Nolte, Stefan; Eilenberger, Falk; Zakoth, David; Mauroner, Oliver; Pertsch, Thomas

2017-08-01

The Abbe School of Photonics (ASP) provides and coordinates the optics and photonics education of graduate and doctoral students at the Friedrich Schiller University in Jena, Germany. The internationalized Master's degree program is the key activity in training students in the optical sciences. The program is designed to provide them with the skills necessary to fill challenging positions in industry and academia. Here, an essential factor is ASP's close collaboration with more than 20 German photonics companies. To sustain these partners' future economic development, the availability of highly qualified employees is constantly required. Accordingly, these industrial partners, the European Union, the local state and the federal German government are strongly involved in the sustainable development of ASP's curriculum by both conceptual and financial engagements. The main goal is to promote the students' academic careers and job experience in the photonics industry as well as in academia. To open up the program to students from all over the world, all ASP lectures and courses are taught in English. ASP's qualification strategy is fully research-oriented and based on the principles of academic freedom, competitive research conditions and internationalization at all levels. The education program is complemented by a structured doctoral student support and a prestigious guest professorship program. Recently, ASP and partners have started a project to build an open photonics laboratory in order to foster innovative and co-creative processes. The idea follows well-established open innovation schemes e.g. in electronics. This Photon Garage (German: "Lichtwerkstatt") will bring together professionals and interested laymen from different backgrounds to approach pertinent challenges in photonics. Here, we will share our latest insights into the potentials and opportunities offered by this novel educative approach.

Advancing colloidal quantum dot photovoltaic technology

NASA Astrophysics Data System (ADS)

Cheng, Yan; Arinze, Ebuka S.; Palmquist, Nathan; Thon, Susanna M.

2016-06-01

Colloidal quantum dots (CQDs) are attractive materials for solar cells due to their low cost, ease of fabrication and spectral tunability. Progress in CQD photovoltaic technology over the past decade has resulted in power conversion efficiencies approaching 10%. In this review, we give an overview of this progress, and discuss limiting mechanisms and paths for future improvement in CQD solar cell technology.We briefly summarize nanoparticle synthesis and film processing methods and evaluate the optoelectronic properties of CQD films, including the crucial role that surface ligands play in materials performance. We give an overview of device architecture engineering in CQD solar cells. The compromise between carrier extraction and photon absorption in CQD photovoltaics is analyzed along with different strategies for overcoming this trade-off. We then focus on recent advances in absorption enhancement through innovative device design and the use of nanophotonics. Several light-trapping schemes, which have resulted in large increases in cell photocurrent, are described in detail. In particular, integrating plasmonic elements into CQD devices has emerged as a promising approach to enhance photon absorption through both near-field coupling and far-field scattering effects. We also discuss strategies for overcoming the single junction efficiency limits in CQD solar cells, including tandem architectures, multiple exciton generation and hybrid materials schemes. Finally, we offer a perspective on future directions for the field and the most promising paths for achieving higher device efficiencies.

Bridging Technometric Method and Innovation Process: An Initial Study

NASA Astrophysics Data System (ADS)

Rumanti, A. A.; Reynaldo, R.; Samadhi, T. M. A. A.; Wiratmadja, I. I.; Dwita, A. C.

2018-03-01

The process of innovation is one of ways utilized to increase the capability of a technology component that reflects the need of SME. Technometric method can be used to identify to what extent the level of technology advancement in a SME is, and also which technology component that needs to be maximized in order to significantly deliver an innovation. This paper serves as an early study, which lays out a conceptual framework that identifies and elaborates the principles of innovation process from a well-established innovation model by Martin with the technometric method, based on the initial background research conducted at SME Ira Silver in Jogjakarta, Indonesia.

The Long and Winding Road to Innovation.

PubMed

Beyar, Rafael

2015-07-30

Medicine is developing through biomedical technology and innovations. The goal of any innovation in medicine is to improve patient care. Exponential growth in technology has led to the unprecedented growth of medical technology over the last 50 years. Clinician-scientists need to understand the complexity of the innovation process, from concept to product release, when working to bring new clinical solutions to the bedside. Hence, an overview of the innovation process is provided herein. The process involves an invention designed to solve an unmet need, followed by prototype design and optimization, animal studies, pilot and pivotal studies, and regulatory approval. The post-marketing strategy relative to funding, along with analysis of cost benefit, is a critical component for the adoption of new technologies. Examples of the road to innovation are provided, based on the experience with development of the transcatheter aortic valve. Finally, ideas are presented to contribute to the further development of this worldwide trend in innovation.

The Long and Winding Road to Innovation

PubMed Central

Beyar, Rafael

2015-01-01

Medicine is developing through biomedical technology and innovations. The goal of any innovation in medicine is to improve patient care. Exponential growth in technology has led to the unprecedented growth of medical technology over the last 50 years. Clinician-scientists need to understand the complexity of the innovation process, from concept to product release, when working to bring new clinical solutions to the bedside. Hence, an overview of the innovation process is provided herein. The process involves an invention designed to solve an unmet need, followed by prototype design and optimization, animal studies, pilot and pivotal studies, and regulatory approval. The post-marketing strategy relative to funding, along with analysis of cost benefit, is a critical component for the adoption of new technologies. Examples of the road to innovation are provided, based on the experience with development of the transcatheter aortic valve. Finally, ideas are presented to contribute to the further development of this worldwide trend in innovation. PMID:26241234

"A Chimera of Sorts": Rethinking Educational Technology Grant Programs, Courseware Innovation, and the Language of Educational Change

ERIC Educational Resources Information Center

Wolff, William I.

2008-01-01

How do we know when an educational organization, process, or courseware tool is "innovative"? How do we define the processes that encourage change or the ways in which faculty "develop" new courseware "innovations"? The terms "innovation", "change", and "development" have been overused in so many contexts that they now seem to have lost their…

Innovation for the future of Irish MedTech industry: retrospective qualitative review of impact of BioInnovate Ireland’s clinical fellows

PubMed Central

McGloughlin, Elizabeth Kate; Anglim, Paul; Keogh, Ivan; Sharif, Faisal

2018-01-01

Clinicians have historically been integral in innovating and developing technology in medicine and surgery. In recent years, however, in an increasingly complex healthcare system, a doctor with innovative ideas is often left behind. Transition from idea to bedside now entails significant hurdles, which often go unrecognised at the outset, particularly for first-time innovators. The BioInnnovate Ireland process, based on the Stanford Biodesign Programme (Identify, Invent and Implement), aims to streamline the process of innovation within the MedTech sector. These programmes focus on needs-based innovation and enable multidisciplinary teams to innovate and collaborate more succinctly. In this preliminary study, the authors aimed to examine the impact of BioInnovate Ireland has had on the clinicians involved and validate the collaborative process. To date, 13 fellows with backgrounds in clinical medicine have participated in the BioInnovate programme. Ten of these clinicians remain involved in clinical innovation projects with four of these working on Enterprise Ireland funded commercialisation grants and one working as chief executive officer of a service-led start-up, Strive. Of these, five also remain engaged in clinical practice on a full or part-time basis. The clinicians who have returned to full-time clinical practice have used the process and learning of the programme to influence their individual clinical areas and actively seek innovative solutions to meet clinical challenges. Clinicians, in particular, describe gaining value from the BioInnovate programme in areas of ‘Understanding Entrepreneurship’ and ‘Business Strategy’. Further study is needed into the quantitative impact on the ecosystem and impact to other stakeholders. PMID:29599999

Innovation for the future of Irish MedTech industry: retrospective qualitative review of impact of BioInnovate Ireland's clinical fellows.

PubMed

McGloughlin, Elizabeth Kate; Anglim, Paul; Keogh, Ivan; Sharif, Faisal

2018-01-01

Clinicians have historically been integral in innovating and developing technology in medicine and surgery. In recent years, however, in an increasingly complex healthcare system, a doctor with innovative ideas is often left behind. Transition from idea to bedside now entails significant hurdles, which often go unrecognised at the outset, particularly for first-time innovators. The BioInnnovate Ireland process, based on the Stanford Biodesign Programme (Identify, Invent and Implement), aims to streamline the process of innovation within the MedTech sector. These programmes focus on needs-based innovation and enable multidisciplinary teams to innovate and collaborate more succinctly. In this preliminary study, the authors aimed to examine the impact of BioInnovate Ireland has had on the clinicians involved and validate the collaborative process. To date, 13 fellows with backgrounds in clinical medicine have participated in the BioInnovate programme. Ten of these clinicians remain involved in clinical innovation projects with four of these working on Enterprise Ireland funded commercialisation grants and one working as chief executive officer of a service-led start-up, Strive. Of these, five also remain engaged in clinical practice on a full or part-time basis. The clinicians who have returned to full-time clinical practice have used the process and learning of the programme to influence their individual clinical areas and actively seek innovative solutions to meet clinical challenges. Clinicians, in particular, describe gaining value from the BioInnovate programme in areas of 'Understanding Entrepreneurship' and 'Business Strategy'. Further study is needed into the quantitative impact on the ecosystem and impact to other stakeholders.

A Novel Fast and Secure Approach for Voice Encryption Based on DNA Computing

NASA Astrophysics Data System (ADS)

Kakaei Kate, Hamidreza; Razmara, Jafar; Isazadeh, Ayaz

2018-06-01

Today, in the world of information communication, voice information has a particular importance. One way to preserve voice data from attacks is voice encryption. The encryption algorithms use various techniques such as hashing, chaotic, mixing, and many others. In this paper, an algorithm is proposed for voice encryption based on three different schemes to increase flexibility and strength of the algorithm. The proposed algorithm uses an innovative encoding scheme, the DNA encryption technique and a permutation function to provide a secure and fast solution for voice encryption. The algorithm is evaluated based on various measures including signal to noise ratio, peak signal to noise ratio, correlation coefficient, signal similarity and signal frequency content. The results demonstrate applicability of the proposed method in secure and fast encryption of voice files

The Blood Stocks Management Scheme, a partnership venture between the National Blood Service of England and North Wales and participating hospitals for maximizing blood supply chain management.

PubMed

Chapman, J F; Cook, R

2002-10-01

The Blood Stocks Management Scheme (BSMS) has been established as a joint venture between the National Blood Service (NBS) in England and North Wales and participating hospitals to monitor the blood supply chain. Stock and wastage data are submitted to a web-based data-management system, facilitating continuous and complete red cell data collection and 'real time' data extraction. The data-management system enables peer review of performance in respect of stock holding levels and red cell wastage. The BSMS has developed an innovative web-based data-management system that enables data collection and benchmarking of practice, which should drive changes in stock management practice, therefore optimizing the use of donated blood.

Scheme dependence and transverse momentum distribution interpretation of Collins-Soper-Sterman resummation

DOE PAGES

Prokudin, Alexei; Sun, Peng; Yuan, Feng

2015-10-01

Following an earlier derivation by Catani-de Florian-Grazzini (2000) on the scheme dependence in the Collins-Soper- Sterman (CSS) resummation formalism in hard scattering processes, we investigate the scheme dependence of the Transverse Momentum Distributions (TMDs) and their applications. By adopting a universal C-coefficient function associated with the integrated parton distributions, the difference between various TMD schemes can be attributed to a perturbative calculable function depending on the hard momentum scale. Thus, we further apply several TMD schemes to the Drell-Yan process of lepton pair production in hadronic collisions, and find that the constrained non-perturbative form factors in different schemes are remarkablymore » consistent with each other and with that of the standard CSS formalism.« less

Scheme dependence and transverse momentum distribution interpretation of Collins-Soper-Sterman resummation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prokudin, Alexei; Sun, Peng; Yuan, Feng

Following an earlier derivation by Catani-de Florian-Grazzini (2000) on the scheme dependence in the Collins-Soper- Sterman (CSS) resummation formalism in hard scattering processes, we investigate the scheme dependence of the Transverse Momentum Distributions (TMDs) and their applications. By adopting a universal C-coefficient function associated with the integrated parton distributions, the difference between various TMD schemes can be attributed to a perturbative calculable function depending on the hard momentum scale. Thus, we further apply several TMD schemes to the Drell-Yan process of lepton pair production in hadronic collisions, and find that the constrained non-perturbative form factors in different schemes are remarkablymore » consistent with each other and with that of the standard CSS formalism.« less

Scheme dependence and transverse momentum distribution interpretation of Collins-Soper-Sterman resummation

NASA Astrophysics Data System (ADS)

Prokudin, Alexei; Sun, Peng; Yuan, Feng

2015-11-01

Following an earlier derivation by Catani, de Florian and Grazzini (2000) on the scheme dependence in the Collins-Soper-Sterman (CSS) resummation formalism in hard scattering processes, we investigate the scheme dependence of the Transverse Momentum Distributions (TMDs) and their applications. By adopting a universal C-coefficient function associated with the integrated parton distributions, the difference between various TMD schemes can be attributed to a perturbative calculable function depending on the hard momentum scale. We further apply several TMD schemes to the Drell-Yan process of lepton pair production in hadronic collisions, and find that the constrained non-perturbative form factors in different schemes are consistent with each other and with that of the standard CSS formalism.

Balancing Accuracy and Computational Efficiency for Ternary Gas Hydrate Systems

NASA Astrophysics Data System (ADS)

White, M. D.

2011-12-01

Geologic accumulations of natural gas hydrates hold vast organic carbon reserves, which have the potential of meeting global energy needs for decades. Estimates of vast amounts of global natural gas hydrate deposits make them an attractive unconventional energy resource. As with other unconventional energy resources, the challenge is to economically produce the natural gas fuel. The gas hydrate challenge is principally technical. Meeting that challenge will require innovation, but more importantly, scientific research to understand the resource and its characteristics in porous media. Producing natural gas from gas hydrate deposits requires releasing CH4 from solid gas hydrate. The conventional way to release CH4 is to dissociate the hydrate by changing the pressure and temperature conditions to those where the hydrate is unstable. The guest-molecule exchange technology releases CH4 by replacing it with a more thermodynamically stable molecule (e.g., CO2, N2). This technology has three advantageous: 1) it sequesters greenhouse gas, 2) it releases energy via an exothermic reaction, and 3) it retains the hydraulic and mechanical stability of the hydrate reservoir. Numerical simulation of the production of gas hydrates from geologic deposits requires accounting for coupled processes: multifluid flow, mobile and immobile phase appearances and disappearances, heat transfer, and multicomponent thermodynamics. The ternary gas hydrate system comprises five components (i.e., H2O, CH4, CO2, N2, and salt) and the potential for six phases (i.e., aqueous, liquid CO2, gas, hydrate, ice, and precipitated salt). The equation of state for ternary hydrate systems has three requirements: 1) phase occurrence, 2) phase composition, and 3) phase properties. Numerical simulation of the production of geologic accumulations of gas hydrates have historically suffered from relatively slow execution times, compared with other multifluid, porous media systems, due to strong nonlinearities and phase transitions. This paper describes and demonstrates a numerical solution scheme for ternary hydrate systems that seeks a balance between accuracy and computational efficiency. This scheme uses a generalize cubic equation of state, functional forms for the hydrate equilibria and cage occupancies, variable switching scheme for phase transitions, and kinetic exchange of hydrate formers (i.e., CH4, CO2, and N2) between the mobile phases (i.e., aqueous, liquid CO2, and gas) and hydrate phase. Accuracy of the scheme will be evaluated by comparing property values and phase equilibria against experimental data. Computational efficiency of the scheme will be evaluated by comparing the base scheme against variants. The application of interest will the production of a natural gas hydrate deposit from a geologic formation, using the guest molecule exchange process; where, a mixture of CO2 and N2 are injected into the formation. During the guest-molecule exchange, CO2 and N2 will predominately replace CH4 in the large and small cages of the sI structure, respectively.

Team-level predictors of innovation at work: a comprehensive meta-analysis spanning three decades of research.

PubMed

Hülsheger, Ute R; Anderson, Neil; Salgado, Jesus F

2009-09-01

This article presents a meta-analysis of team-level antecedents of creativity and innovation in the workplace. Using a general input-process-output model, the authors examined 15 team-level variables researched in primary studies published over the last 30 years and their relation to creativity and innovation. An exhaustive search of the international innovation literature resulted in a final sample (k) of 104 independent studies. Results revealed that team process variables of support for innovation, vision, task orientation, and external communication displayed the strongest relationships with creativity and innovation (rhos between 0.4 and 0.5). Input variables (i.e., team composition and structure) showed weaker effect sizes. Moderator analyses confirmed that relationships differ substantially depending on measurement method (self-ratings vs. independent ratings of innovation) and measurement level (individual vs. team innovation). Team variables displayed considerably stronger relationships with self-report measures of innovation compared with independent ratings and objective criteria. Team process variables were more strongly related to creativity and innovation measured at the team than the individual level. Implications for future research and pragmatic ramifications for organizational practice are discussed in conclusion.

Legal and Regulatory Barriers to Reverse Innovation.

PubMed

Rowthorn, Virginia; Plum, Alexander J; Zervos, John

Reverse innovation, or the importation of new, affordable, and efficacious models to high-income countries from the developing world, has emerged as a way to improve the health care system in the United States. Reverse innovation has been identified as a key emerging trend in global health systems in part because low-resourced settings are particularly good laboratories for low-cost/high-impact innovations that are developed out of necessity. A difficult question receiving scant attention is that of legal and regulatory barriers. The objective of this paper is to understand and elucidate the legal barriers faced by innovators bringing health interventions to the United States. Semistructured qualitative interviews were conducted with 9 key informants who have directly participated in the introduction of global health care approaches to the United States health system. A purposive sampling scheme was employed to identify participants. Phone interviews were conducted over one week in July 2016 with each participant and lasted an average of 35 minutes each. Purely legal barriers included questions surrounding tort liability, standard of care, and concerns around patient-administered self-care. Regulatory burdens included issues of international medical licensure, reimbursement, and task shifting and scope of work challenges among nonprofessionals (e.g. community health workers). Finally, perceived (i.e. not realized or experienced) legal and regulatory barriers to innovative modalities served as disincentives to bringing products or services developed outside of the United States to the United States market. Conflicting interests within the health care system, safety concerns, and little value placed on low-cost interventions inhibit innovation. Legal and regulatory barriers rank among, and contribute to, an anti-innovation atmosphere in healthcare for domestic and reverse innovators alike. Reverse innovation should be fostered through the thoughtful development of legal and regulatory standards that encourage the introduction and scalable adoption of successful health care innovations developed outside of the US, particularly innovations that support public health goals and do not have the benefit of a large corporate sponsor to facilitate introduction to the market. Copyright © 2016 Icahn School of Medicine at Mount Sinai. Published by Elsevier Inc. All rights reserved.

Innovation and wound healing.

PubMed

Harding, Keith

2015-04-01

Innovation in medicine requires unique partnerships between academic research, biotech or pharmaceutical companies, and health-care providers. While innovation in medicine has greatly increased over the past 100 years, innovation in wound care has been slow, despite the fact that chronic wounds are a global health challenge where there is a need for technical, process and social innovation. While novel partnerships between research and the health-care system have been created, we still have much to learn about wound care and the wound-healing processes.

Efficient bit sifting scheme of post-processing in quantum key distribution

NASA Astrophysics Data System (ADS)

Li, Qiong; Le, Dan; Wu, Xianyan; Niu, Xiamu; Guo, Hong

2015-10-01

Bit sifting is an important step in the post-processing of quantum key distribution (QKD). Its function is to sift out the undetected original keys. The communication traffic of bit sifting has essential impact on the net secure key rate of a practical QKD system. In this paper, an efficient bit sifting scheme is presented, of which the core is a lossless source coding algorithm. Both theoretical analysis and experimental results demonstrate that the performance of the scheme is approaching the Shannon limit. The proposed scheme can greatly decrease the communication traffic of the post-processing of a QKD system, which means the proposed scheme can decrease the secure key consumption for classical channel authentication and increase the net secure key rate of the QKD system, as demonstrated by analyzing the improvement on the net secure key rate. Meanwhile, some recommendations on the application of the proposed scheme to some representative practical QKD systems are also provided.

Impact of point-of-care implementation of Xpert® MTB/RIF: product vs. process innovation.

PubMed

Schumacher, S G; Thangakunam, B; Denkinger, C M; Oliver, A A; Shakti, K B; Qin, Z Z; Michael, J S; Luo, R; Pai, M; Christopher, D J

2015-09-01

Both product innovation (e.g., more sensitive tests) and process innovation (e.g., a point-of-care [POC] testing programme) could improve patient outcomes. To study the respective contributions of product and process innovation in improving patient outcomes. We implemented a POC programme using Xpert(®) MTB/RIF in an out-patient clinic of a tertiary care hospital in India. We measured the impact of process innovation by comparing time to diagnosis with routine testing vs. POC testing. We measured the impact of product innovation by comparing accuracy and time to diagnosis using smear microscopy vs. POC Xpert. We enrolled 1012 patients over a 15-month period. Xpert had high accuracy, but the incremental value of one Xpert over two smears was only 6% (95%CI 3-12). Implementing Xpert as a routine laboratory test did not reduce the time to diagnosis compared to smear-based diagnosis. In contrast, the POC programme reduced the time to diagnosis by 5.5 days (95%CI 4.3-6.7), but required dedicated staff and substantial adaptation of clinic workflow. Process innovation by way of a POC Xpert programme had a greater impact on time to diagnosis than the product per se, and can yield important improvements in patient care that are complementary to those achieved by introducing innovative technologies.

[Innovative medicines and market access agreements].

PubMed

Toumi, M; Zard, J; Duvillard, R; Jommi, C

2013-09-01

Market Access Agreements (MAA) for drugs have emerged in response to the need to control health expenditures, as well as to the uncertainty about the true benefit of a drug. It is possible to group MAA in two types of agreements: financial agreements and outcome-based agreements. MAA is a growing trend and is shifting towards conditional access. However, the willingness to use these contracts and their implementation differ across countries, and some are still resistant to put them in place. The MAA challenges to overcome encompass the complexity of the schemes, the administrative burden and the difficulty of evaluating MAA. It is likely that these agreements might experience further evolution in the future to become a faster pathway for therapeutic innovations, at a fair price. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

ABLE project: Development of an advanced lead-acid storage system for autonomous PV installations

NASA Astrophysics Data System (ADS)

Lemaire-Potteau, Elisabeth; Vallvé, Xavier; Pavlov, Detchko; Papazov, G.; Borg, Nico Van der; Sarrau, Jean-François

In the advanced battery for low-cost renewable energy (ABLE) project, the partners have developed an advanced storage system for small and medium-size PV systems. It is composed of an innovative valve-regulated lead-acid (VRLA) battery, optimised for reliability and manufacturing cost, and an integrated regulator, for optimal battery management and anti-fraudulent use. The ABLE battery performances are comparable to flooded tubular batteries, which are the reference in medium-size PV systems. The ABLE regulator has several innovative features regarding energy management and modular series/parallel association. The storage system has been validated by indoor, outdoor and field tests, and it is expected that this concept could be a major improvement for large-scale implementation of PV within the framework of national rural electrification schemes.

Molecular Innovations Toward Theranostics of Aggressive Prostate Cancer

DTIC Science & Technology

2014-09-01

specific membrane antigen ( PSMA ) for prostate cancer theranostic application. Task 5 (Months 9 – 30): In vivo and PET/CT imaging evaluation of the...separate the entire synthesis into several subunits as shown in Scheme 1. The PSMA targeting ligand 4 has been synthesized in a conventional chemistry way...6]. To retain the PSMA targeting ligand affinity after integration into the MDCs, a PEG5 and a Boc-lysine linker has been introduced to form

Protocol, Engineering Research Center, University of California, Santa Barbara

DTIC Science & Technology

2005-12-01

minimizing the energy consumption in idle periods. We have designed an asynchronous wakeup schedule based on the theory of block designs. The idea is...performance of ad hoc networks through innovative packet scheduling (Baker). "* Developed a number of novel schemes to ensure loop freedom in on demand routing...network nodes to schedule their transmissions to avoid collisions (Garcia-Luna-Aceves). "* Designed and analyzed the Hybrid Activation Multiple Access (HAMA

A high-order relativistic two-fluid electrodynamic scheme with consistent reconstruction of electromagnetic fields and a multidimensional Riemann solver for electromagnetism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Balsara, Dinshaw S., E-mail: dbalsara@nd.edu; Amano, Takanobu, E-mail: amano@eps.s.u-tokyo.ac.jp; Garain, Sudip, E-mail: sgarain@nd.edu

In various astrophysics settings it is common to have a two-fluid relativistic plasma that interacts with the electromagnetic field. While it is common to ignore the displacement current in the ideal, classical magnetohydrodynamic limit, when the flows become relativistic this approximation is less than absolutely well-justified. In such a situation, it is more natural to consider a positively charged fluid made up of positrons or protons interacting with a negatively charged fluid made up of electrons. The two fluids interact collectively with the full set of Maxwell's equations. As a result, a solution strategy for that coupled system of equationsmore » is sought and found here. Our strategy extends to higher orders, providing increasing accuracy. The primary variables in the Maxwell solver are taken to be the facially-collocated components of the electric and magnetic fields. Consistent with such a collocation, three important innovations are reported here. The first two pertain to the Maxwell solver. In our first innovation, the magnetic field within each zone is reconstructed in a divergence-free fashion while the electric field within each zone is reconstructed in a form that is consistent with Gauss' law. In our second innovation, a multidimensionally upwinded strategy is presented which ensures that the magnetic field can be updated via a discrete interpretation of Faraday's law and the electric field can be updated via a discrete interpretation of the generalized Ampere's law. This multidimensional upwinding is achieved via a multidimensional Riemann solver. The multidimensional Riemann solver automatically provides edge-centered electric field components for the Stokes law-based update of the magnetic field. It also provides edge-centered magnetic field components for the Stokes law-based update of the electric field. The update strategy ensures that the electric field is always consistent with Gauss' law and the magnetic field is always divergence-free. This collocation also ensures that electromagnetic radiation that is propagating in a vacuum has both electric and magnetic fields that are exactly divergence-free. Coupled relativistic fluid dynamic equations are solved for the positively and negatively charged fluids. The fluids' numerical fluxes also provide a self-consistent current density for the update of the electric field. Our reconstruction strategy ensures that fluid velocities always remain sub-luminal. Our third innovation consists of an efficient design for several popular IMEX schemes so that they provide strong coupling between the finite-volume-based fluid solver and the electromagnetic fields at high order. This innovation makes it possible to efficiently utilize high order IMEX time update methods for stiff source terms in the update of high order finite-volume methods for hyperbolic conservation laws. We also show that this very general innovation should extend seamlessly to Runge–Kutta discontinuous Galerkin methods. The IMEX schemes enable us to use large CFL numbers even in the presence of stiff source terms. Several accuracy analyses are presented showing that our method meets its design accuracy in the MHD limit as well as in the limit of electromagnetic wave propagation. Several stringent test problems are also presented. We also present a relativistic version of the GEM problem, which shows that our algorithm can successfully adapt to challenging problems in high energy astrophysics.« less

A high-order relativistic two-fluid electrodynamic scheme with consistent reconstruction of electromagnetic fields and a multidimensional Riemann solver for electromagnetism

NASA Astrophysics Data System (ADS)

Balsara, Dinshaw S.; Amano, Takanobu; Garain, Sudip; Kim, Jinho

2016-08-01

In various astrophysics settings it is common to have a two-fluid relativistic plasma that interacts with the electromagnetic field. While it is common to ignore the displacement current in the ideal, classical magnetohydrodynamic limit, when the flows become relativistic this approximation is less than absolutely well-justified. In such a situation, it is more natural to consider a positively charged fluid made up of positrons or protons interacting with a negatively charged fluid made up of electrons. The two fluids interact collectively with the full set of Maxwell's equations. As a result, a solution strategy for that coupled system of equations is sought and found here. Our strategy extends to higher orders, providing increasing accuracy. The primary variables in the Maxwell solver are taken to be the facially-collocated components of the electric and magnetic fields. Consistent with such a collocation, three important innovations are reported here. The first two pertain to the Maxwell solver. In our first innovation, the magnetic field within each zone is reconstructed in a divergence-free fashion while the electric field within each zone is reconstructed in a form that is consistent with Gauss' law. In our second innovation, a multidimensionally upwinded strategy is presented which ensures that the magnetic field can be updated via a discrete interpretation of Faraday's law and the electric field can be updated via a discrete interpretation of the generalized Ampere's law. This multidimensional upwinding is achieved via a multidimensional Riemann solver. The multidimensional Riemann solver automatically provides edge-centered electric field components for the Stokes law-based update of the magnetic field. It also provides edge-centered magnetic field components for the Stokes law-based update of the electric field. The update strategy ensures that the electric field is always consistent with Gauss' law and the magnetic field is always divergence-free. This collocation also ensures that electromagnetic radiation that is propagating in a vacuum has both electric and magnetic fields that are exactly divergence-free. Coupled relativistic fluid dynamic equations are solved for the positively and negatively charged fluids. The fluids' numerical fluxes also provide a self-consistent current density for the update of the electric field. Our reconstruction strategy ensures that fluid velocities always remain sub-luminal. Our third innovation consists of an efficient design for several popular IMEX schemes so that they provide strong coupling between the finite-volume-based fluid solver and the electromagnetic fields at high order. This innovation makes it possible to efficiently utilize high order IMEX time update methods for stiff source terms in the update of high order finite-volume methods for hyperbolic conservation laws. We also show that this very general innovation should extend seamlessly to Runge-Kutta discontinuous Galerkin methods. The IMEX schemes enable us to use large CFL numbers even in the presence of stiff source terms. Several accuracy analyses are presented showing that our method meets its design accuracy in the MHD limit as well as in the limit of electromagnetic wave propagation. Several stringent test problems are also presented. We also present a relativistic version of the GEM problem, which shows that our algorithm can successfully adapt to challenging problems in high energy astrophysics.

Beyond Making the Case, Creating the Space for Innovation.

PubMed

Boston-Fleischhauer, Carol

2016-06-01

Disruptive innovation results in something different from incremental change. Instead of focusing on improving an existing process, product, or service through performance improvement, disruptive innovation disregards status quo service or work and uses very different approaches to change, seeking to design the product, process, or service according to the consumer's perspective versus the providers' By its very nature, disruptive innovation provokes organizational, professional, and cultural controversy.

System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction.

PubMed

Singh, Ravendra; Ierapetritou, Marianthi; Ramachandran, Rohit

2013-11-01

The next generation of QbD based pharmaceutical products will be manufactured through continuous processing. This will allow the integration of online/inline monitoring tools, coupled with an efficient advanced model-based feedback control systems, to achieve precise control of process variables, so that the predefined product quality can be achieved consistently. The direct compaction process considered in this study is highly interactive and involves time delays for a number of process variables due to sensor placements, process equipment dimensions, and the flow characteristics of the solid material. A simple feedback regulatory control system (e.g., PI(D)) by itself may not be sufficient to achieve the tight process control that is mandated by regulatory authorities. The process presented herein comprises of coupled dynamics involving slow and fast responses, indicating the requirement of a hybrid control scheme such as a combined MPC-PID control scheme. In this manuscript, an efficient system-wide hybrid control strategy for an integrated continuous pharmaceutical tablet manufacturing process via direct compaction has been designed. The designed control system is a hybrid scheme of MPC-PID control. An effective controller parameter tuning strategy involving an ITAE method coupled with an optimization strategy has been used for tuning of both MPC and PID parameters. The designed hybrid control system has been implemented in a first-principles model-based flowsheet that was simulated in gPROMS (Process System Enterprise). Results demonstrate enhanced performance of critical quality attributes (CQAs) under the hybrid control scheme compared to only PID or MPC control schemes, illustrating the potential of a hybrid control scheme in improving pharmaceutical manufacturing operations. Copyright © 2013 Elsevier B.V. All rights reserved.

Optimizing the discovery organization for innovation.

PubMed

Sams-Dodd, Frank

2005-08-01

Strategic management is the process of adapting organizational structure and management principles to fit the strategic goal of the business unit. The pharmaceutical industry has generally been expert at optimizing its organizations for drug development, but has rarely implemented different structures for the early discovery process, where the objective is innovation and the transformation of innovation into drug projects. Here, a set of strategic management methods is proposed, covering team composition, organizational structure, management principles and portfolio management, which are designed to increase the level of innovation in the early drug discovery process.

The impact of innovation intermediary on knowledge transfer

NASA Astrophysics Data System (ADS)

Lin, Min; Wei, Jun

2018-07-01

Many firms have opened up their innovation process and actively transfer knowledge with external partners in the market of technology. To reduce some of the market inefficiencies, more and more firms collaborate with innovation intermediaries. In light of the increasing importance of intermediary in the context of open innovation, we in this paper systematically investigate the effect of innovation intermediary on knowledge transfer and innovation process in networked systems. We find that the existence of innovation intermediary is conducive to the knowledge diffusion and facilitate the knowledge growth at system level. Interestingly, the scale of the innovation intermediary has little effect on the growth of knowledge. We further investigate the selection of intermediary members by comparing four selection strategies: random selection, initial knowledge level based selection, absorptive capability based selection, and innovative ability based selection. It is found that the selection strategy based on innovative ability outperforms all the other strategies in promoting the system knowledge growth. Our study provides a theoretical understanding of the impact of innovation intermediary on knowledge transfer and sheds light on the design and selection of innovation intermediary in open innovation.

A chronic scheme of cranial window preparation to study pial vascular reactivity in murine cerebral malaria

PubMed Central

Ong, Peng Kai; Meays, Diana; Frangos, John A.; Carvalho, Leonardo J.M.

2013-01-01

Objective The acute implantation of a cranial window for studying cerebroarteriolar reactivity in living animals involves a highly surgically-invasive craniotomy procedure at the time of experimentation, which limits its application in severely ill animals such as in the experimental murine model of cerebral malaria (ECM). To overcome this problem, a chronic window implantation scheme was designed and implemented. Methods A partial craniotomy is first performed by creating a skull bone flap in the healthy mice, which are then left to recover for 1–2 weeks, followed by infection to induce ECM. Uninfected animals are utilized as control. When cranial superfusion is needed, the bone flap is retracted and window implantation completed by assembling a perfusion chamber for compound delivery to the exposed brain surface. The presurgical step is intended to minimize surgical trauma on the day of experimentation. Results Chronic preparations in uninfected mice exhibited remarkably improved stability over acute ones by significantly reducing periarteriolar tissue damage and enhancing cerebroarteriolar dilator responses. The chronic scheme was successfully implemented in ECM mice which unveiled novel preliminary insights on impaired cerebroarteriolar reactivity and eNOS dysfunction. Conclusion The chronic scheme presents an innovative approach for advancing our mechanistic understanding on cerebrovascular dysfunction in ECM. PMID:23279271

The experience of Ghana in implementing a user fee exemption policy to provide free delivery care.

PubMed

Witter, Sophie; Arhinful, Daniel Kojo; Kusi, Anthony; Zakariah-Akoto, Sawudatu

2007-11-01

In resource-poor countries, the high cost of user fees for deliveries limits access to skilled attendance, and contributes to maternal and neonatal mortality and the impoverishment of vulnerable households. A growing number of countries are experimenting with different approaches to tackling financial barriers to maternal health care. This paper describes an innovative scheme introduced in Ghana in 2003 to exempt all pregnant women from payments for delivery, in which public, mission and private providers could claim back lost user fee revenues, according to an agreed tariff. The paper presents part of the findings of an evaluation of the policy based on interviews with 65 key informants in the health system at national, regional, district and facility level, including policymakers, managers and providers. The exemption mechanism was well accepted and appropriate, but there were important problems with disbursing and sustaining the funding, and with budgeting and management. Staff workloads increased as more women attended, and levels of compensation for services and staff were important to the scheme's acceptance. At the end of 2005, a national health insurance scheme, intended to include full maternal health care cover, was starting up in Ghana, and it was not yet clear how the exemptions scheme would fit into it.

Sensorless optimal sinusoidal brushless direct current for hard disk drives

NASA Astrophysics Data System (ADS)

Soh, C. S.; Bi, C.

2009-04-01

Initiated by the availability of digital signal processors and emergence of new applications, market demands for permanent magnet synchronous motors have been surging. As its back-emf is sinusoidal, the drive current should also be sinusoidal for reducing the torque ripple. However, in applications like hard disk drives, brushless direct current (BLDC) drive is adopted instead of sinusoidal drive for simplification. The adoption, however, comes at the expense of increased harmonics, losses, torque pulsations, and acoustics. In this paper, we propose a sensorless optimal sinusoidal BLDC drive. First and foremost, the derivation for an optimal sinusoidal drive is presented, and a power angle control scheme is proposed to achieve an optimal sinusoidal BLDC. The scheme maintains linear relationship between the motor speed and drive voltage. In an attempt to execute the sensorless drive, an innovative power angle measurement scheme is devised, which takes advantage of the freewheeling diodes and measures the power angle through the detection of diode voltage drops. The objectives as laid out will be presented and discussed in this paper, supported by derivations, simulations, and experimental results. The proposed scheme is straightforward, brings about the benefits of sensorless sinusoidal drive, negates the need for current sensors by utilizing the freewheeling diodes, and does not incur additional cost.

An Integrated H-G Scheme Identifying Areas for Soil Remediation and Primary Heavy Metal Contributors: A Risk Perspective.

PubMed

Zou, Bin; Jiang, Xiaolu; Duan, Xiaoli; Zhao, Xiuge; Zhang, Jing; Tang, Jingwen; Sun, Guoqing

2017-03-23

Traditional sampling for soil pollution evaluation is cost intensive and has limited representativeness. Therefore, developing methods that can accurately and rapidly identify at-risk areas and the contributing pollutants is imperative for soil remediation. In this study, we propose an innovative integrated H-G scheme combining human health risk assessment and geographical detector methods that was based on geographical information system technology and validated its feasibility in a renewable resource industrial park in mainland China. With a discrete site investigation of cadmium (Cd), arsenic (As), copper (Cu), mercury (Hg) and zinc (Zn) concentrations, the continuous surfaces of carcinogenic risk and non-carcinogenic risk caused by these heavy metals were estimated and mapped. Source apportionment analysis using geographical detector methods further revealed that these risks were primarily attributed to As, according to the power of the determinant and its associated synergic actions with other heavy metals. Concentrations of critical As and Cd, and the associated exposed CRs are closed to the safe thresholds after remediating the risk areas identified by the integrated H-G scheme. Therefore, the integrated H-G scheme provides an effective approach to support decision-making for regional contaminated soil remediation at fine spatial resolution with limited sampling data over a large geographical extent.

Proton Beam Intensity Upgrades for the Neutrino Program at Fermilab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhat, C. M.

2016-12-15

Fermilab is committed to upgrading its accelerator complex towards the intensity frontier to pursue HEP research in the neutrino sector and beyond. The upgrade has two steps: 1) the Proton Improvement Plan (PIP), which is underway, has its primary goal to start providing 700 kW beam power on NOvA target by the end of 2017 and 2) the foreseen PIP–II will replace the existing LINAC, a 400 MeV injector to the Booster, by an 800 MeV superconducting LINAC by the middle of next decade, with output beam intensity from the Booster increased significantly and the beam power on the NOvAmore » target increased to <1.2 MW. In any case, the Fermilab Booster is going to play a very significant role for the next two decades. In this context, we have recently developed and commissioned an innovative beam injection scheme for the Booster called "early injection scheme". This scheme is already in operation and has a potential to increase the Booster beam intensity from the PIP design goal by a considerable amount with a reduced beam emittance and beam loss. In this paper, we will present results from our experience from the new scheme in operation, current status and future plans.« less

A Robust Multi-Scale Modeling System for the Study of Cloud and Precipitation Processes

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2012-01-01

During the past decade, numerical weather and global non-hydrostatic models have started using more complex microphysical schemes originally developed for high resolution cloud resolving models (CRMs) with 1-2 km or less horizontal resolutions. These microphysical schemes affect the dynamic through the release of latent heat (buoyancy loading and pressure gradient) the radiation through the cloud coverage (vertical distribution of cloud species), and surface processes through rainfall (both amount and intensity). Recently, several major improvements of ice microphysical processes (or schemes) have been developed for cloud-resolving model (Goddard Cumulus Ensemble, GCE, model) and regional scale (Weather Research and Forecast, WRF) model. These improvements include an improved 3-ICE (cloud ice, snow and graupel) scheme (Lang et al. 2010); a 4-ICE (cloud ice, snow, graupel and hail) scheme and a spectral bin microphysics scheme and two different two-moment microphysics schemes. The performance of these schemes has been evaluated by using observational data from TRMM and other major field campaigns. In this talk, we will present the high-resolution (1 km) GeE and WRF model simulations and compared the simulated model results with observation from recent field campaigns [i.e., midlatitude continental spring season (MC3E; 2010), high latitude cold-season (C3VP, 2007; GCPEx, 2012), and tropical oceanic (TWP-ICE, 2006)].

[Risk sharing methods in middle income countries].

PubMed

Inotai, András; Kaló, Zoltán

2012-01-01

The pricing strategy of innovative medicines is based on the therapeutic value in the largest pharmaceutical markets. The cost-effectiveness of new medicines with value based ex-factory price is justifiable. Due to the international price referencing and parallel trade the ex-factory price corridor of new medicines has been narrowed in recent years. Middle income countries have less negotiation power to change the narrow drug pricing corridor, although their fair intention is to buy pharmaceuticals at lower price from their scarce public resources compared to higher income countries. Therefore the reimbursement of new medicines at prices of Western-European countries may not be justifiable in Central-Eastern European countries. Confidential pricing agreements (i.e. confidential price discounts, claw-back or rebate) in lower income countries of the European Union can alleviate this problem, as prices of new medicines can be adjusted to local purchasing power without influencing the published ex-factory price and so the accessibility of patients to these drugs in other countries. In order to control the drug budget payers tend to apply financial risk sharing agreements for new medicines in more and more countries to shift the consequences of potential overspending to pharmaceutical manufacturers. The major paradox of financial risk-sharing schemes is that increased mortality, poor persistence of patients, reduced access to healthcare providers, and no treatment reduce pharmaceutical spending. Consequently, payers have started to apply outcome based risk sharing agreements for new medicines recently to improve the quality of health care provision. Our paper aims to review and assess the published financial and outcome based risk sharing methods. Introduction of outcome based risk-sharing schemes can be a major advancement in the drug reimbursement strategy of payers in middle income countries. These schemes can help to reduce the medical uncertainty in coverage decisions for valuable innovative healthcare technologies. However risk-sharing schemes can also reduce the transparency of pharmaceutical pricing and reimbursement, as the payback, and consequently the actual price per patient can be calculated only retrospectively. Therefore risk-sharing agreements can be interpreted as special forms of confidential pricing agreements to facilitate the implementation of differential pricing in middle income countries.

Innovation: an emerging focus from cells to societies.

PubMed

Hochberg, Michael E; Marquet, Pablo A; Boyd, Robert; Wagner, Andreas

2017-12-05

Innovations are generally unexpected, often spectacular changes in phenotypes and ecological functions. The contributions to this theme issue are the latest conceptual, theoretical and experimental developments, addressing how ecology, environment, ontogeny and evolution are central to understanding the complexity of the processes underlying innovations. Here, we set the stage by introducing and defining key terms relating to innovation and discuss their relevance to biological, cultural and technological change. Discovering how the generation and transmission of novel biological information, environmental interactions and selective evolutionary processes contribute to innovation as an ecosystem will shed light on how the dominant features across life come to be, generalize to social, cultural and technological evolution, and have applications in the health sciences and sustainability.This article is part of the theme issue 'Process and pattern in innovations from cells to societies'. © 2017 The Author(s).

Innovation: an emerging focus from cells to societies

PubMed Central

Boyd, Robert

2017-01-01

Innovations are generally unexpected, often spectacular changes in phenotypes and ecological functions. The contributions to this theme issue are the latest conceptual, theoretical and experimental developments, addressing how ecology, environment, ontogeny and evolution are central to understanding the complexity of the processes underlying innovations. Here, we set the stage by introducing and defining key terms relating to innovation and discuss their relevance to biological, cultural and technological change. Discovering how the generation and transmission of novel biological information, environmental interactions and selective evolutionary processes contribute to innovation as an ecosystem will shed light on how the dominant features across life come to be, generalize to social, cultural and technological evolution, and have applications in the health sciences and sustainability. This article is part of the theme issue ‘Process and pattern in innovations from cells to societies’. PMID:29061887

From the abstract to the concrete - Implementation of an innovative tool in home care.

PubMed

Kajamaa, Anu; Schulz, Klaus-Peter

2018-02-01

Background The implementation of innovations in practice is a critical factor for change and development processes in health and home care. We therefore analyze how an innovative tool - a mobility agreement to maintain physical mobility of home care clients - was implemented in Finnish home care. Methods Our study involves ethnographic research of 13 home care visits, two years after the mobility agreement was implemented. We analyze the emergence of contradictions, the motives of the actors and the use of artifacts supporting or inhibiting the implementation. Two in-depth cases illustrate the implementation of the mobility agreement in home care visits. Findings Our findings show that, first, to achieve practice change and development, the innovation implementation requires the overcoming of contradictions in the implementation process. Second, it calls for the emergence of a shared motive between the actors to transform the abstract concept of an innovation into a concrete practice. Third, artifacts, customary to the clients are important in supporting the implementation process. Fourth, the implementation brings about a modification of the innovation and the adopting social system. Conclusions Innovation implementation should be seen as a transformation process of an abstract concept into a concrete practice, enabled by the actors involved. Concept design and implementation should be closely linked. In health/home care innovation management, the implementation of innovations needs to be understood as a complex collective learning process. Results can be far reaching - in our case leading to change of home care workers' professional understanding and elderly clients' mobility habits.

An efficient numerical method for solving the Boltzmann equation in multidimensions

NASA Astrophysics Data System (ADS)

Dimarco, Giacomo; Loubère, Raphaël; Narski, Jacek; Rey, Thomas

2018-01-01

In this paper we deal with the extension of the Fast Kinetic Scheme (FKS) (Dimarco and Loubère, 2013 [26]) originally constructed for solving the BGK equation, to the more challenging case of the Boltzmann equation. The scheme combines a robust and fast method for treating the transport part based on an innovative Lagrangian technique supplemented with conservative fast spectral schemes to treat the collisional operator by means of an operator splitting approach. This approach along with several implementation features related to the parallelization of the algorithm permits to construct an efficient simulation tool which is numerically tested against exact and reference solutions on classical problems arising in rarefied gas dynamic. We present results up to the 3 D × 3 D case for unsteady flows for the Variable Hard Sphere model which may serve as benchmark for future comparisons between different numerical methods for solving the multidimensional Boltzmann equation. For this reason, we also provide for each problem studied details on the computational cost and memory consumption as well as comparisons with the BGK model or the limit model of compressible Euler equations.

Adaptive Approximation-Based Regulation Control for a Class of Uncertain Nonlinear Systems Without Feedback Linearizability.

PubMed

Wang, Ning; Sun, Jing-Chao; Han, Min; Zheng, Zhongjiu; Er, Meng Joo

2017-09-06

In this paper, for a general class of uncertain nonlinear (cascade) systems, including unknown dynamics, which are not feedback linearizable and cannot be solved by existing approaches, an innovative adaptive approximation-based regulation control (AARC) scheme is developed. Within the framework of adding a power integrator (API), by deriving adaptive laws for output weights and prediction error compensation pertaining to single-hidden-layer feedforward network (SLFN) from the Lyapunov synthesis, a series of SLFN-based approximators are explicitly constructed to exactly dominate completely unknown dynamics. By the virtue of significant advancements on the API technique, an adaptive API methodology is eventually established in combination with SLFN-based adaptive approximators, and it contributes to a recursive mechanism for the AARC scheme. As a consequence, the output regulation error can asymptotically converge to the origin, and all other signals of the closed-loop system are uniformly ultimately bounded. Simulation studies and comprehensive comparisons with backstepping- and API-based approaches demonstrate that the proposed AARC scheme achieves remarkable performance and superiority in dealing with unknown dynamics.

Prosodic expectations in silent reading: ERP evidence from rhyme scheme and semantic congruence in classic Chinese poems.

PubMed

Chen, Qingrong; Zhang, Jingjing; Xu, Xiaodong; Scheepers, Christoph; Yang, Yiming; Tanenhaus, Michael K

2016-09-01

In an ERP study, classic Chinese poems with a well-known rhyme scheme were used to generate an expectation of a rhyme in the absence of an expectation for a specific character. Critical characters were either consistent or inconsistent with the expected rhyme scheme and semantically congruent or incongruent with the content of the poem. These stimuli allowed us to examine whether a top-down rhyme scheme expectation would affect relatively early components of the ERP associated with character-to-sound mapping (P200) and lexically-mediated semantic processing (N400). The ERP data revealed that rhyme scheme congruence, but not semantic congruence modulated the P200: rhyme-incongruent characters elicited a P200 effect across the head demonstrating that top-down expectations influence early phonological coding of the character before lexical-semantic processing. Rhyme scheme incongruence also produced a right-lateralized N400-like effect. Moreover, compared to semantically congruous poems, semantically incongruous poems produced a larger N400 response only when the character was consistent with the expected rhyme scheme. The results suggest that top-down prosodic expectations can modulate early phonological processing in visual word recognition, indicating that prosodic expectations might play an important role in silent reading. They also suggest that semantic processing is influenced by general knowledge of text genre. Copyright © 2016 Elsevier B.V. All rights reserved.

Organizational Dimensions of Innovative Practice: A Qualitative Investigation of the Processes Supporting Innovation Adoption in Outpatient Physical Therapy Practice.

PubMed

Sabus, Carla; Spake, Ellen

2018-01-01

The ability to innovate and adapt practice is a requirement of the progressive healthcare provider. Innovative practice by rehabilitation providers has largely been approached as personal professional development; this study extends that perspective by examining innovation uptake from the organizational level. The varied professions can be expected to have distinct qualities of innovation adoption that reflect professional norms, values, and expectations. The purpose of this qualitative study was to describe the organizational processes of innovation uptake in outpatient physical therapy practice. Through nomination, two outpatient, privately owned physical therapy clinics were identified as innovation practices. Eighteen physical therapists, three owners, and a manager participated in the study. The two clinics served as case studies within a grounded theory approach. Data were collected through observation, unstructured questioning, work flow analysis, focus group sessions, and artifact analysis. Data were analyzed and coded among the investigators. A theoretical model of the innovation adoption process in outpatient physical therapy practice was developed. Elements of the model included (1) change grounded in relationship-centered care, (2) clinic readiness to accept change, and (3) clinic adaptability and resilience. A social paradigm of innovation adoption informed through this research complements the concentration on personal professional development.

The parallel algorithm for the 2D discrete wavelet transform

NASA Astrophysics Data System (ADS)

Barina, David; Najman, Pavel; Kleparnik, Petr; Kula, Michal; Zemcik, Pavel

2018-04-01

The discrete wavelet transform can be found at the heart of many image-processing algorithms. Until now, the transform on general-purpose processors (CPUs) was mostly computed using a separable lifting scheme. As the lifting scheme consists of a small number of operations, it is preferred for processing using single-core CPUs. However, considering a parallel processing using multi-core processors, this scheme is inappropriate due to a large number of steps. On such architectures, the number of steps corresponds to the number of points that represent the exchange of data. Consequently, these points often form a performance bottleneck. Our approach appropriately rearranges calculations inside the transform, and thereby reduces the number of steps. In other words, we propose a new scheme that is friendly to parallel environments. When evaluating on multi-core CPUs, we consistently overcome the original lifting scheme. The evaluation was performed on 61-core Intel Xeon Phi and 8-core Intel Xeon processors.

INSPIRE Science Internship Camps at SMVDU; Forum for Engagement of Higher Secondary School Students for Promotion of Innovative Pursuit of Science

NASA Astrophysics Data System (ADS)

Wanchoo, S. K.; Vaishnavi, S.

2016-12-01

INSPIRE Science Internship Camps at SMVDU: forum for engagement of higher secondary students for promotion of innovative pursuit of science Samantha Vaishnavi1 and Sunil K. Wanchoo2*1Department of Biotechnology, SMVD University, Katra, INDIA 2Department of Physics, SMVD University, Katra, INDIA AbstractIndia recognizes that, to become a knowledge economy and take advantage of its demographic dividend in years to come, young bright minds need to be attracted to science, and be motivated to take up challenging research problems. Our union government, in the year 2008, launched INSPIRE (Innovation in Science Pursuit for Inspired Research), an initiative by the Department of Science & Technology, Government of India. Under the INSPIRE scheme and as a part of subcomponent called Scheme for Early Attraction of Talent (SEATS) an aim was set forth to attract children to pursue science by inviting 50000 top 1% merit rank holders in 10th boards and pursuing science in class 11th to be part of such camps organized annually by higher education institutions throughout the country. During these camps, students are made to interact with mentors - who are eminent scientists and gifted teachers to experience and reveal the joy of innovation. As a part of this initiative, we have organized 10 fully residential INSPIRE Science Internship Camps so far since April 2010. These have been attended by 3590 students from all over the State of Jammu and Kashmir. Two of these camps have been successfully held in the difficult and challenging terrain of Leh, Ladakh with the help of state administration and Army. In July 2015, we had the distinction of organizing the largest camp in India, attended by 620 students. 11th such camp and 3rd at Leh shall be held in the second week of September, 2016. We shall present the detailed approach adopted in organizing these camps and the feedback received from the attendees and some of the mentors. *Corresponding author (sunilkwanchoo@gmail.com)

Innovation in patient-centered care: lessons from a qualitative study of innovative health care organizations in Washington State

PubMed Central

2012-01-01

Background Growing interest in the promise of patient-centered care has led to numerous health care innovations, including the patient-centered medical home, shared decision-making, and payment reforms. How best to vet and adopt innovations is an open question. Washington State has been a leader in health care reform and is a rich laboratory for patient-centered innovations. We sought to understand the process of patient-centered care innovation undertaken by innovative health care organizations – from strategic planning to goal selection to implementation to maintenance. Methods We conducted key-informant interviews with executives at five health plans, five provider organizations, and ten primary care clinics in Washington State. At least two readers of each interview transcript identified themes inductively; final themes were determined by consensus. Results Innovation in patient-centered care was a strategic objective chosen by nearly every organization in this study. However, other goals were paramount: cost containment, quality improvement, and organization survival. Organizations commonly perceived effective chronic disease management and integrated health information technology as key elements for successful patient-centered care innovation. Inertia, resource deficits, fee-for-service payment, and regulatory limits on scope of practice were cited as barriers to innovation, while organization leadership, human capital, and adaptive culture facilitated innovation. Conclusions Patient-centered care innovations reflected organizational perspectives: health plans emphasized cost-effectiveness while providers emphasized health care delivery processes. Health plans and providers shared many objectives, yet the two rarely collaborated to achieve them. The process of innovation is heavily dependent on organizational culture and leadership. Policymakers can improve the pace and quality of patient-centered innovation by setting targets and addressing conditions for innovation. PMID:23241305

Innovation in patient-centered care: lessons from a qualitative study of innovative health care organizations in Washington State.

PubMed

Reed, Peter; Conrad, Douglas A; Hernandez, Susan E; Watts, Carolyn; Marcus-Smith, Miriam

2012-12-14

Growing interest in the promise of patient-centered care has led to numerous health care innovations, including the patient-centered medical home, shared decision-making, and payment reforms. How best to vet and adopt innovations is an open question. Washington State has been a leader in health care reform and is a rich laboratory for patient-centered innovations. We sought to understand the process of patient-centered care innovation undertaken by innovative health care organizations - from strategic planning to goal selection to implementation to maintenance. We conducted key-informant interviews with executives at five health plans, five provider organizations, and ten primary care clinics in Washington State. At least two readers of each interview transcript identified themes inductively; final themes were determined by consensus. Innovation in patient-centered care was a strategic objective chosen by nearly every organization in this study. However, other goals were paramount: cost containment, quality improvement, and organization survival. Organizations commonly perceived effective chronic disease management and integrated health information technology as key elements for successful patient-centered care innovation. Inertia, resource deficits, fee-for-service payment, and regulatory limits on scope of practice were cited as barriers to innovation, while organization leadership, human capital, and adaptive culture facilitated innovation. Patient-centered care innovations reflected organizational perspectives: health plans emphasized cost-effectiveness while providers emphasized health care delivery processes. Health plans and providers shared many objectives, yet the two rarely collaborated to achieve them. The process of innovation is heavily dependent on organizational culture and leadership. Policymakers can improve the pace and quality of patient-centered innovation by setting targets and addressing conditions for innovation.

A Systems Dynamics Model of Implementation of an Innovation.

ERIC Educational Resources Information Center

Gaynor, Alan K.; And Others

The research presented in this report investigated the critical factors that affected the decision to abandon or replace a curricular innovation in one elementary school. The specific innovation examined in this research is called developing mathematical processes, which emphasizes process and induction rather than computational skills. Although…

Biomedical device innovation methodology: applications in biophotonics

NASA Astrophysics Data System (ADS)

Beswick, Daniel M.; Kaushik, Arjun; Beinart, Dylan; McGarry, Sarah; Yew, Ming Khoon; Kennedy, Brendan F.; Maria, Peter Luke Santa

2018-02-01

The process of medical device innovation involves an iterative method that focuses on designing innovative, device-oriented solutions that address unmet clinical needs. This process has been applied to the field of biophotonics with many notable successes. Device innovation begins with identifying an unmet clinical need and evaluating this need through a variety of lenses, including currently existing solutions for the need, stakeholders who are interested in the need, and the market that will support an innovative solution. Only once the clinical need is understood in detail can the invention process begin. The ideation phase often involves multiple levels of brainstorming and prototyping with the aim of addressing technical and clinical questions early and in a cost-efficient manner. Once potential solutions are found, they are tested against a number of known translational factors, including intellectual property, regulatory, and reimbursement landscapes. Only when the solution matches the clinical need, the next phase of building a "to market" strategy should begin. Most aspects of the innovation process can be conducted relatively quickly and without significant capital expense. This white paper focuses on key points of the medical device innovation method and how the field of biophotonics has been applied within this framework to generate clinical and commercial success.

Study of stability of the difference scheme for the model problem of the gaslift process

NASA Astrophysics Data System (ADS)

Temirbekov, Nurlan; Turarov, Amankeldy

2017-09-01

The paper studies a model of the gaslift process where the motion in a gas-lift well is described by partial differential equations. The system describing the studied process consists of equations of motion, continuity, equations of thermodynamic state, and hydraulic resistance. A two-layer finite-difference Lax-Vendroff scheme is constructed for the numerical solution of the problem. The stability of the difference scheme for the model problem is investigated using the method of a priori estimates, the order of approximation is investigated, the algorithm for numerical implementation of the gaslift process model is given, and the graphs are presented. The development and investigation of difference schemes for the numerical solution of systems of equations of gas dynamics makes it possible to obtain simultaneously exact and monotonic solutions.

Evidence use in decision-making on introducing innovations: a systematic scoping review with stakeholder feedback.

PubMed

Turner, Simon; D'Lima, Danielle; Hudson, Emma; Morris, Stephen; Sheringham, Jessica; Swart, Nick; Fulop, Naomi J

2017-12-04

A range of evidence informs decision-making on innovation in health care, including formal research findings, local data and professional opinion. However, cultural and organisational factors often prevent the translation of evidence for innovations into practice. In addition to the characteristics of evidence, it is known that processes at the individual level influence its impact on decision-making. Less is known about the ways in which processes at the professional, organisational and local system level shape evidence use and its role in decisions to adopt innovations. A systematic scoping review was used to review the health literature on innovations within acute and primary care and map processes at the professional, organisational and local system levels which influence how evidence informs decision-making on innovation. Stakeholder feedback on the themes identified was collected via focus groups to test and develop the findings. Following database and manual searches, 31 studies reporting primary qualitative data met the inclusion criteria: 24 were of sufficient methodological quality to be included in the thematic analysis. Evidence use in decision-making on innovation is influenced by multi-level processes (professional, organisational, local system) and interactions across these levels. Preferences for evidence vary by professional group and health service setting. Organisations can shape professional behaviour by requiring particular forms of evidence to inform decision-making. Pan-regional organisations shape innovation decision-making at lower levels. Political processes at all levels shape the selection and use of evidence in decision-making. The synthesis of results from primary qualitative studies found that evidence use in decision-making on innovation is influenced by processes at multiple levels. Interactions between different levels shape evidence use in decision-making (e.g. professional groups and organisations can use local systems to validate evidence and legitimise innovations, while local systems can tailor or frame evidence to influence activity at lower levels). Organisational leaders need to consider whether the environment in which decisions are made values diverse evidence and stakeholder perspectives. Further qualitative research on decision-making practices that highlights how and why different types of evidence come to count during decisions, and tracks the political aspects of decisions about innovation, is needed.

Value driven innovation in medical device design: a process for balancing stakeholder voices.

PubMed

de Ana, F J; Umstead, K A; Phillips, G J; Conner, C P

2013-09-01

The innovation process has often been represented as a linear process which funnels customer needs through various business and process filters. This method may be appropriate for some consumer products, but in the medical device industry there are some inherent limitations to the traditional innovation funnel approach. In the medical device industry, there are a number of stakeholders who need to have their voices heard throughout the innovation process. Each stakeholder has diverse and unique needs relating to the medical device, the needs of one may highly affect the needs of another, and the relationships between stakeholders may be tenuous. This paper describes the application of a spiral innovation process to the development of a medical device which considers three distinct stakeholder voices: the Voice of the Customer, the Voice of the Business and the Voice of the Technology. The process is presented as a case study focusing on the front-end redesign of a class III medical device for an orthopedics company. Starting from project initiation and scope alignment, the process describes four phases, Discover, Envision, Create, and Refine, and concludes with value assessment of the final design features.

Concept Engineering: An Investigation Of TIME versus Market Orientation in Product Concept Development

DTIC Science & Technology

1993-06-01

Designers and Champions of Innovation. Journal of Product Innovation Management . Vol. 8,91-103 Barabba, V. P., & Zaltman, G. (1991). Hearing the Voice of...Kleinschmidt, E. K. (1986). An Investigation into the New Product Process: Steps, Deficiencies, and Impact. Journal of Product Innovation Management . Vol...Product and Process Development. Journal of Product Innovation Management . Vol. 4,81-88 Goodman, M. (1974). Study Notes in System Dynamics. Cambridge, MA

Combination of decentralized waste drying and SSF techniques for household biowaste minimization and ethanol production.

PubMed

Sotiropoulos, A; Vourka, I; Erotokritou, A; Novakovic, J; Panaretou, V; Vakalis, S; Thanos, T; Moustakas, K; Malamis, D

2016-06-01

The results of the demonstration of an innovative household biowaste management and treatment scheme established in two Greek Municipalities for the production of lignocellulosic ethanol using dehydrated household biowaste as a substrate, are presented within this research. This is the first time that biowaste drying was tested at a decentralized level for the production of ethanol using the Simultaneous Saccharification and Fermentation (SSF) process, at a pilot scale in Greece. The decentralized biowaste drying method proved that the household biowaste mass and volume reduction may reach 80% through the dehydration process used. The chemical characteristics related to lignocellulosic ethanol production have proved to differ substantially between seasons thus; special attention should be given to the process applied for ethanol production mainly regarding the enzyme quality and quantity used during the pretreatment stage. The maximum ethanol production achieved was 29.12g/L, approximately 60% of the maximum theoretical yield based on the substrate's sugar content. The use of the decentralized waste drying as an alternative approach for household biowaste minimization and the production of second generation ethanol is considered to be a promising approach for efficient biowaste management and treatment in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

Innovation by coercion: Emerging institutionalization of university-industry collaborations in Russia.

PubMed

Bychkova, Olga

2016-08-01

This article explores the emerging institutionalization of collaborative university-industry networks in Russia. The Russian government has attempted to use a top-down public policy scheme to stimulate and promote network-building in the R&D sector. In order to understand the initial organizational responses that universities and companies select while structuring collaborations, the article utilizes conceptual perspectives from institutional theory, especially drawing on arguments from strategic choice, network-building, and network failure studies.

Innovative production technology ethanol from sweet sorghum

NASA Astrophysics Data System (ADS)

Kashapov, N. F.; Nafikov, M. M.; Gazetdinov, M. X.; Nafikova, M. M.; Nigmatzyanov, A. R.

2016-06-01

The paper considers the technological aspects of production of ethanol from nontraditional for Russian Federation crops - sweet sorghum. Presents the technological scheme of alcohol production and fuel pellets from sweet sorghum. Special attention is paid to assessing the efficiency of alcohol production from sweet sorghum. The described advantage of sugar content in stem juice of sweet sorghum compared with other raw materials. Allegedly, the use of the technology for producing alcohol from sweet sorghum allows to save resources.

Mapping Mangrove Density from Rapideye Data in Central America

NASA Astrophysics Data System (ADS)

Son, Nguyen-Thanh; Chen, Chi-Farn; Chen, Cheng-Ru

2017-06-01

Mangrove forests provide a wide range of socioeconomic and ecological services for coastal communities. Extensive aquaculture development of mangrove waters in many developing countries has constantly ignored services of mangrove ecosystems, leading to unintended environmental consequences. Monitoring the current status and distribution of mangrove forests is deemed important for evaluating forest management strategies. This study aims to delineate the density distribution of mangrove forests in the Gulf of Fonseca, Central America with Rapideye data using the support vector machines (SVM). The data collected in 2012 for density classification of mangrove forests were processed based on four different band combination schemes: scheme-1 (bands 1-3, 5 excluding the red-edge band 4), scheme-2 (bands 1-5), scheme-3 (bands 1-3, 5 incorporating with the normalized difference vegetation index, NDVI), and scheme-4 (bands 1-3, 5 incorporating with the normalized difference red-edge index, NDRI). We also hypothesized if the obvious contribution of Rapideye red-edge band could improve the classification results. Three main steps of data processing were employed: (1), data pre-processing, (2) image classification, and (3) accuracy assessment to evaluate the contribution of red-edge band in terms of the accuracy of classification results across these four schemes. The classification maps compared with the ground reference data indicated the slightly higher accuracy level observed for schemes 2 and 4. The overall accuracies and Kappa coefficients were 97% and 0.95 for scheme-2 and 96.9% and 0.95 for scheme-4, respectively.

Selecting for creativity and innovation potential: implications for practice in healthcare education.

PubMed

Patterson, Fiona; Zibarras, Lara Dawn

2017-05-01

The ability to innovate is an important requirement in many organisations. Despite this pressing need, few selection systems in healthcare focus on identifying the potential for creativity and innovation and so this area has been vastly under-researched. As a first step towards understanding how we might select for creativity and innovation, this paper explores the use of a trait-based measure of creativity and innovation potential, and evaluates its efficacy for use in selection for healthcare education. This study uses a sample of 188 postgraduate physicians applying for education and training in UK General Practice. Participants completed two questionnaires (a trait-based measure of creativity and innovation, and a measure of the Big Five personality dimensions) and were also rated by assessors on creative problem solving measured during a selection centre. In exploring the construct validity of the trait-based measure of creativity and innovation, our research clarifies the associations between personality, and creativity and innovation. In particular, our study highlights the importance of motivation in the creativity and innovation process. Results also suggest that Openness to Experience is positively related to creativity and innovation whereas some aspects of Conscientiousness are negatively associated with creativity and innovation. Results broadly support the utility of using a trait-based measure of creativity and innovation in healthcare selection processes, although practically this may be best delivered as part of an interview process, rather than as a screening tool. Findings are discussed in relation to broader implications for placing more priority on creativity and innovation as selection criteria within healthcare education and training in future.

Applying a structured innovation process to interventional radiology: a single-center experience.

PubMed

Sista, Akhilesh K; Hwang, Gloria L; Hovsepian, David M; Sze, Daniel Y; Kuo, William T; Kothary, Nishita; Louie, John D; Yamada, Kei; Hong, Richard; Dhanani, Riaz; Brinton, Todd J; Krummel, Thomas M; Makower, Joshua; Yock, Paul G; Hofmann, Lawrence V

2012-04-01

To determine the feasibility and efficacy of applying an established innovation process to an active academic interventional radiology (IR) practice. The Stanford Biodesign Medical Technology Innovation Process was used as the innovation template. Over a 4-month period, seven IR faculty and four IR fellow physicians recorded observations. These observations were converted into need statements. One particular need relating to gastrostomy tubes was diligently screened and was the subject of a single formal brainstorming session. Investigators collected 82 observations, 34 by faculty and 48 by fellows. The categories that generated the most observations were enteral feeding (n = 9, 11%), biopsy (n = 8, 10%), chest tubes (n = 6, 7%), chemoembolization and radioembolization (n = 6, 7%), and biliary interventions (n = 5, 6%). The output from the screening on the gastrostomy tube need was a specification sheet that served as a guidance document for the subsequent brainstorming session. The brainstorming session produced 10 concepts under three separate categories. This formalized innovation process generated numerous observations and ultimately 10 concepts to potentially to solve a significant clinical need, suggesting that a structured process can help guide an IR practice interested in medical innovation. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

Innovation and the English National Health Service: a qualitative study of the independent sector treatment centre programme.

PubMed

Turner, Simon; Allen, Pauline; Bartlett, Will; Pérotin, Virginie

2011-08-01

Over the past two decades, an international trend of exposing public health services to different forms of economic organisation has emerged. In the English National Health Service (NHS), care is currently provided through a quasi-market including 'diverse' providers from the private and third sector. The predominant scheme through which private sector companies have been awarded NHS contracts is the Independent Sector Treatment Centre (ISTC) programme. ISTCs were designed to produce innovative models of service delivery for elective care and stimulate innovation among incumbent NHS providers. This paper investigates these claims using qualitative data on the impact of an ISTC upon a local health economy (LHE) composed of NHS organisations in England. Using the case of elective orthopaedic surgery, we conducted semi-structured interviews with senior managers from incumbent NHS providers and an ISTC in 2009. We show that ISTCs exhibit a different relationship with frontline clinicians because they counteract the power of professional communities associated with the NHS. This has positive and negative consequences for innovation. ISTCs have introduced new routines unencumbered by the extant norms of professional communities, but they appear to represent weaker learning environments and do not reproduce cooperation across organisational boundaries to the same extent as incumbent NHS providers. Copyright © 2011 Elsevier Ltd. All rights reserved.

A fast CT reconstruction scheme for a general multi-core PC.

PubMed

Zeng, Kai; Bai, Erwei; Wang, Ge

2007-01-01

Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have been developing for the past several years. To accelerate the reconstruction process using the filtered backprojection (FBP) method, specialized hardware or graphics cards can be used. However, specialized hardware is expensive and not flexible. The graphics processing unit (GPU) in a current graphic card can only reconstruct images in a reduced precision and is not easy to program. In this paper, an acceleration scheme is proposed based on a multi-core PC. In the proposed scheme, several techniques are integrated, including utilization of geometric symmetry, optimization of data structures, single-instruction multiple-data (SIMD) processing, multithreaded computation, and an Intel C++ compilier. Our scheme maintains the original precision and involves no data exchange between the GPU and CPU. The merits of our scheme are demonstrated in numerical experiments against the traditional implementation. Our scheme achieves a speedup of about 40, which can be further improved by several folds using the latest quad-core processors.

A Fast CT Reconstruction Scheme for a General Multi-Core PC

PubMed Central

Zeng, Kai; Bai, Erwei; Wang, Ge

2007-01-01

Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have been developing for the past several years. To accelerate the reconstruction process using the filtered backprojection (FBP) method, specialized hardware or graphics cards can be used. However, specialized hardware is expensive and not flexible. The graphics processing unit (GPU) in a current graphic card can only reconstruct images in a reduced precision and is not easy to program. In this paper, an acceleration scheme is proposed based on a multi-core PC. In the proposed scheme, several techniques are integrated, including utilization of geometric symmetry, optimization of data structures, single-instruction multiple-data (SIMD) processing, multithreaded computation, and an Intel C++ compilier. Our scheme maintains the original precision and involves no data exchange between the GPU and CPU. The merits of our scheme are demonstrated in numerical experiments against the traditional implementation. Our scheme achieves a speedup of about 40, which can be further improved by several folds using the latest quad-core processors. PMID:18256731

Time cycle analysis and simulation of material flow in MOX process layout

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chakraborty, S.; Saraswat, A.; Danny, K.M.

The (U,Pu)O{sub 2} MOX fuel is the driver fuel for the upcoming PFBR (Prototype Fast Breeder Reactor). The fuel has around 30% PuO{sub 2}. The presence of high percentages of reprocessed PuO{sub 2} necessitates the design of optimized fuel fabrication process line which will address both production need as well as meet regulatory norms regarding radiological safety criteria. The powder pellet route has highly unbalanced time cycle. This difficulty can be overcome by optimizing process layout in terms of equipment redundancy and scheduling of input powder batches. Different schemes are tested before implementing in the process line with the helpmore » of a software. This software simulates the material movement through the optimized process layout. The different material processing schemes have been devised and validity of the schemes are tested with the software. Schemes in which production batches are meeting at any glove box location are considered invalid. A valid scheme ensures adequate spacing between the production batches and at the same time it meets the production target. This software can be further improved by accurately calculating material movement time through glove box train. One important factor is considering material handling time with automation systems in place.« less

The Innovation Paradox: A Selective Review of the Literature on Action Learning and Innovation

ERIC Educational Resources Information Center

Pedler, Mike; Brook, Cheryl

2017-01-01

This paper explores selective literatures in the two fields of action learning and innovation, and seeks insights into the processes of, and connections between, innovation, engagement and implementation. We searched the action learning articles for references to innovation, beginning with the work of Revans, who highlights the innovation paradox,…

Innovative financing instruments for global health 2002-15: a systematic analysis.

PubMed

Atun, Rifat; Silva, Sachin; Knaul, Felicia M

2017-07-01

Development assistance for health (DAH), the value of which peaked in 2013 and fell in 2015, is unlikely to rise substantially in the near future, increasing reliance on domestic and innovative financing sources to sustain health programmes in low-income and middle-income countries. We examined innovative financing instruments (IFIs)-financing schemes that generate and mobilise funds-to estimate the quantum of financing mobilised from 2002 to 2015. We identified ten IFIs, which mobilised US$8·9 billion (2·3% of overall DAH) in 2002-15. The funds generated by IFIs were channelled mostly through GAVI and the Global Fund, and used for programmes for new and underused vaccines, HIV/AIDS, malaria, tuberculosis, and maternal and child health. Vaccination programmes received the largest amount of funding ($2·6 billion), followed by HIV/AIDS ($1080·7 million) and malaria ($1028·9 million), with no discernible funding targeted to non-communicable diseases. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.

System thinking shaping innovation ecosystems

NASA Astrophysics Data System (ADS)

Abreu, António; Urze, Paula

2016-11-01

Over the last few decades, there has been a trend to build innovation platforms as enablers for groups of companies to jointly develop new products and services. As a result, the notion of co-innovation is getting wider acceptance. However, a critical issue that is still open, despite some efforts in this area, is the lack of tools and models that explain the synergies created in a co-innovation process. In this context, the present paper aims at discussing the advantages of applying a system thinking approach to understand the mechanisms associated with co-innovation processes. Finally, based on experimental results from a Portuguese co-innovation network, a discussion on the benefits, challenges and difficulties found are presented and discussed.

Future changes in precipitation of the baiu season under RCP scenarios

NASA Astrophysics Data System (ADS)

Okada, Y.; Takemi, T.; Ishikawa, H.

2014-12-01

Recently, the relationship between global warming and rainfall during the rainy season, which called the baiu in Japan, has been attracting attention in association with heavy rainfall in this period. In the Innovative Program of Climate Change Projection for the 21st Century, many studies show a delay in the northward march of the baiu front, and significant increase of daily precipitation amounts around western Japan during the late baiu season (e.g., Kusunoki et al. 2011, Kanada et al. 2012). The future climate experiment in these studies was performed under the IPCC SRES A1B scenarios for global warming conditions. In this study, we discuss the future changes in precipitation using calculated 60km-mesh model (MRI-AGCM3.2H) under Representative Concentration Pathways (RCP) scenarios. Support of this dataset is provided by the Meteorological Research Institute (MRI). These dataset are calculated by setting the Yoshimura (YS) scheme mainly.Seasonal progression of future precipitation generally indicates the northward in RCP2.6 and 4.5 scenarios, around western Japan. In RCP6.0 scenario, precipitation intensity is weak compared to the other scenarios. RCP8.5 scenario is calculated by setting three different cumulus schemes (YS, Arakawa-Schubert (AS), and Kain-Fritsch (KF) schemes). RCP8.5 configured in YS scheme showed that the rainband associated with the baiu front is not clear. Moreover, peak is remarkable during late June. In AS scheme, the precipitation area stagnates around 30 N until August. And it in KF scheme shows gradual northward migration.This work was conducted under the Program for Risk Information on Climate Change supported by the Ministry of Education, Culture, Sports, Science, and Technology-Japan (MEXT).

An analysis of hydrogen production via closed-cycle schemes. [thermochemical processings from water

NASA Technical Reports Server (NTRS)

Chao, R. E.; Cox, K. E.

1975-01-01

A thermodynamic analysis and state-of-the-art review of three basic schemes for production of hydrogen from water: electrolysis, thermal water-splitting, and multi-step thermochemical closed cycles is presented. Criteria for work-saving thermochemical closed-cycle processes are established, and several schemes are reviewed in light of such criteria. An economic analysis is also presented in the context of energy costs.

Multidimensional Framework for the Analysis of Innovations at Universities in Catalonia

ERIC Educational Resources Information Center

Tomas, Marina; Castro, Diego

2011-01-01

The purpose of this paper is to contribute to a better understanding of the nature of change processes and dynamics at Catalan universities. A multidimensional approach was adopted to examine the change processes and to analyse organizational innovation in higher education. The paper draws involved in each particular innovation. Analysis of these…

Spaces of Innovation: Experiences from Two Small High-Tech Firms

ERIC Educational Resources Information Center

Heiskanen, Tuula; Heiskanen, Hannu

2011-01-01

Purpose: By comparing two small high-tech firms specialising in medical technology this article seeks to answer the following questions: What are the key characteristics of innovation processes in the case firms? How do the mutual relationships between mental, social and physical spaces explain the different pathways in the innovation processes in…

School Innovation: The Mutual Impacts of Organizational Learning and Creativity

ERIC Educational Resources Information Center

McCharen, Belinda; Song, JiHoon; Martens, Jon

2011-01-01

The primary aim of this research is to identify cultural determinants of organizational learning and knowledge creation practices, which could be the driving factors for the innovation process in school settings (Mulford, 1998; Silins et al., 2002). A conceptual process model for school innovation was developed. In contrast to previous approaches,…

Mental Healthcare Delivery in London-Middlesex Ontario - The Next Frontier.

PubMed

Velji, Karima; Links, Paul

2016-01-01

The next frontier for mental healthcare delivery will be focused on three facets of innovation, namely structure, process and outcome. The structure innovation will seek to develop new models of care delivery between the two hospitals and with the community. The process innovation will focus on embedding strategies to adopt a recovery and rehabilitation approach to care delivery. Lastly, the outcome innovation will use system wide quality improvement methods to drive breakthrough performance in mental healthcare.

Study for new hardmask process scheme

NASA Astrophysics Data System (ADS)

Lee, Daeyoup; Tatti, Phillip; Lee, Richard; Chang, Jack; Cho, Winston; Bae, Sanggil

2017-03-01

Hardmask processes are a key technique to enable low-k semiconductors, but they can have an impact on patterning control, influencing defectivity, alignment, and overlay. Specifically, amorphous carbon layer (ACL) hardmask schemes can negatively affect overlay by creating distorted alignment signals. A new scheme needs to be developed that can be inserted where amorphous carbon is used but provide better alignment performance. Typical spin-on carbon (SOC) materials used in other hardmask schemes have issues with DCD-FCD skew. In this paper we will evaluate new spin-on carbon material with a higher carbon content that could be a candidate to replace amorphous carbon.

Dark Energy Survey Year 1 Results: Weak Lensing Shape Catalogues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zuntz, J.; et al.

We present two galaxy shape catalogues from the Dark Energy Survey Year 1 data set, covering 1500 square degrees with a median redshift ofmore » $0.59$. The catalogues cover two main fields: Stripe 82, and an area overlapping the South Pole Telescope survey region. We describe our data analysis process and in particular our shape measurement using two independent shear measurement pipelines, METACALIBRATION and IM3SHAPE. The METACALIBRATION catalogue uses a Gaussian model with an innovative internal calibration scheme, and was applied to $riz$-bands, yielding 34.8M objects. The IM3SHAPE catalogue uses a maximum-likelihood bulge/disc model calibrated using simulations, and was applied to $r$-band data, yielding 21.9M objects. Both catalogues pass a suite of null tests that demonstrate their fitness for use in weak lensing science. We estimate the 1$$\\sigma$$ uncertainties in multiplicative shear calibration to be $0.013$ and $0.025$ for the METACALIBRATION and IM3SHAPE catalogues, respectively.« less

Sustainable management for the eastern Mediterranean coast of Turkey.

PubMed

Berberoglu, Süha

2003-03-01

The objective of this article is to propose a program for the integrated coastal zone management that is required to stimulate and guide sustainable development of the Mediterranean coastal zone of Turkey. Improved data collection, quality control, analysis, and data management will provide a firm basis for future scientific understanding of the East Mediterranean coast of Turkey and will support long-term management. Various innovative procedures were proposed for a promising ecosystem-based approach to manage coastal wetlands in the Mediterranean: remote data acquisition with new technologies; environmental quality monitoring program that will provide a baseline for monitoring; linking a Geographic Information System (GIS) with natural resource management decision routines in the context of operational wetlands, fisheries, tourism management system; environmental sensitivity analysis to ensure that permitted developments are environmentally sustainable; and use of natural species to restore the wetlands and coastal dunes and sustain the system processes. The proposed management scheme will benefit the scientific community in the Mediterranean and the management/planning community in Eastern Turkey.

[Challenges and countermeasures of forestry schistosomiasis control programs in ecological priority of Yangtze River economic belt development].

PubMed

Ning, Su; Yong-Jie, Xu

2016-12-13

Relevant projects carried out within the Yangtze River economic belt on the impact of schistosomiasis epidemic and transmission are important issues for "ecological priority" in the process of implementing the strategy. The key problems of schistosomiasis epidemic risk, epidemic happening repeatedly, difficulty of rehabilitating Oncomelania hupensis snail control and schistosomiasis prevention forest, lag of evaluation system and platform construction, lack of basic research, et al. were analyzed in the Yangtze River economic belt taking "ecological priority" as the basis in this paper. Then corresponding countermeasures to these challenges were put forward so as to provide the reference for the national forestry schistosomiasis control programs, which include: execution of the comprehensive prevention and control strategy, scheming of the new round of forestry schistosomiasis control programs, strengthening schistosomiasis prevention and control, promoting productivity in existing forestry to consolidate and improve the achievements of previous forestry schistosomiasis control programs, and promoting the intensity of technological innovation to improve the technological level of forestry schistosomiasis control programs.

PUBLISHER'S ANNOUNCEMENT: Important changes for 2008

NASA Astrophysics Data System (ADS)

2008-01-01

This issue, the first of 2008, sees a new innovation for Journal of Physics G: Nuclear and Particle Physics (J. Phys. G). J. Phys. G has moved from page numbering to an article numbering system, which offers important advantages to our authors. It increases flexibility and speeds up the publication process as papers in different issues or subject sections can now be published online as soon as they are ready, without having to wait for a whole issue or section to be allocated page numbers. The bibliographic citation style will therefore change for articles published from now on. Articles should be referenced using the six-digit article number in place of a page number. Please note that this number must include any leading zeros. For example: Smith J et al 2008 J. Phys. G: Nucl. Part. Phys. 35 015045 If you have any questions or comments about our new scheme, please contact us at http://jphysg@iop.org J. Phys. G Publishing Team

Cathodic protection for pipelines crossing the Mackenzie River at Norman Wells, Northwest Territories, Canada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiskel, B.J.; Wozniewski, A.

This paper reports on an oil production facility at Norman Wells, N.W.T. The production is centered around the Mackenzie River with oil being produced from wells located on natural and artificial islands as well as from wells located on the mainland. Pipelines have been installed beneath the river to route production from the islands back to the central processing plant on the mainland. Cathodic protection was required for the pipelines crossing the Mackenzie River to prevent external corrosion in an environmentally sensitive area. Several difficulties were encountered in preparing an optimum cathodic design due to the unique production scheme, permafrostmore » and logistical problems associated with the northern location. An innovative approach was therefore required for the design, installation and testing of the cathodic protection system. This paper describes evolution of the cathodic protection system from a conventional one to a system utilizing a close groundbed concept and unique current return path.« less

An Innovative Infrastructure with a Universal Geo-Spatiotemporal Data Representation Supporting Cost-Effective Integration of Diverse Earth Science Data

NASA Technical Reports Server (NTRS)

Rilee, Michael Lee; Kuo, Kwo-Sen

2017-01-01

The SpatioTemporal Adaptive Resolution Encoding (STARE) is a unifying scheme encoding geospatial and temporal information for organizing data on scalable computing/storage resources, minimizing expensive data transfers. STARE provides a compact representation that turns set-logic functions into integer operations, e.g. conditional sub-setting, taking into account representative spatiotemporal resolutions of the data in the datasets. STARE geo-spatiotemporally aligns data placements of diverse data on massive parallel resources to maximize performance. Automating important scientific functions (e.g. regridding) and computational functions (e.g. data placement) allows scientists to focus on domain-specific questions instead of expending their efforts and expertise on data processing. With STARE-enabled automation, SciDB (Scientific Database) plus STARE provides a database interface, reducing costly data preparation, increasing the volume and variety of interoperable data, and easing result sharing. Using SciDB plus STARE as part of an integrated analysis infrastructure dramatically eases combining diametrically different datasets.

Development of Technology and Installation for Biohydrogen Production

NASA Astrophysics Data System (ADS)

Pridvizhkin, S. V.; Vyguzova, M. A.; Bazhenov, O. V.

2017-11-01

The article discusses the method for hydrogen production and the device this method application. The relevance of the use of renewable fuels and the positive impact of renewable energy on the environment and the economy is also considered. The presented technology relates to a method for hydrogen production from organic materials subject to anaerobic fermentation, such as the components of solid municipal waste, sewage sludge and agricultural enterprises wastes, sewage waste. The aim of the research is to develop an effective eco-friendly technology for hydrogen producing within an industrial project To achieve the goal, the following issues have been addressed in the course of the study: - development of the process schemes for hydrogen producing from organic materials; - development of the technology for hydrogen producing; - optimization of a biogas plant with the aim of hydrogen producing at one of the fermentation stages; - approbation of the research results. The article is recommended for engineers and innovators working on the renewable energy development issues.

Licensing in an international triopoly

NASA Astrophysics Data System (ADS)

Ferreira, Fernanda A.; Ferreira, Flávio

2011-12-01

We study the effects of entry of two foreign firms on domestic welfare in the presence of licensing, when the incumbent is technologically superior to the entrants. We consider two different situations: (i) the cost-reducing innovation is licensed to both entrants; (ii) the cost-reducing innovation is licensed to just one of the entrants. We analyse three kind of license: (lump-sum) fixed-fee; (per-unit) royalty; and two-part tariff, that is a combination of a fixed-fee and a royalty. We prove that a two part tariff is never an optimal licensing scheme for the incumbent. Moreover, (i) when the technology is licensed to the two entrants, the optimal contract consists of a licensing with only output royalty; and (ii) when the technology is licensed to just one of the entrants, the optimal contract consists of a licensing with only a fixed-fee.

Development and Implications of a Predictive Cost Methodology for Modular Pumped Storage Hydropower (m-PSH) Projects in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Witt, Adam; Chalise, Dol Raj; Hadjerioua, Boualem

The slow pace of Pumped Storage Hydropower development in the US over the past twenty years has led to widespread interest in the feasibility and viability of alternative PSH designs, development schemes, and technologies. Since 2011, Oak Ridge National Lab has been exploring the economic viability of modular Pumped Storage Hydropower (m-PSH) development through targeted case studies, revenue simulations, and analysis of innovative configurations and designs. This paper outlines the development and supporting analysis of a scalable, comprehensive cost modeling tool designed to simulate the initial capital costs for a variety of potential m-PSH projects and deployment scenarios. The toolmore » is used to explore and determine innovative research strategies that can improve the economic viability of m-PSH in US markets.« less

Implementation of a Cross-Layer Sensing Medium-Access Control Scheme.

PubMed

Su, Yishan; Fu, Xiaomei; Han, Guangyao; Xu, Naishen; Jin, Zhigang

2017-04-10

In this paper, compressed sensing (CS) theory is utilized in a medium-access control (MAC) scheme for wireless sensor networks (WSNs). We propose a new, cross-layer compressed sensing medium-access control (CL CS-MAC) scheme, combining the physical layer and data link layer, where the wireless transmission in physical layer is considered as a compress process of requested packets in a data link layer according to compressed sensing (CS) theory. We first introduced using compressive complex requests to identify the exact active sensor nodes, which makes the scheme more efficient. Moreover, because the reconstruction process is executed in a complex field of a physical layer, where no bit and frame synchronizations are needed, the asynchronous and random requests scheme can be implemented without synchronization payload. We set up a testbed based on software-defined radio (SDR) to implement the proposed CL CS-MAC scheme practically and to demonstrate the validation. For large-scale WSNs, the simulation results show that the proposed CL CS-MAC scheme provides higher throughput and robustness than the carrier sense multiple access (CSMA) and compressed sensing medium-access control (CS-MAC) schemes.

CTAB Recommendations on Learning Environments for Innovation.

ERIC Educational Resources Information Center

Branscomb, Anne W.; And Others

The report examines cultural and social forces in the United States which discourage innovation and creativity. The history of American innovation is reviewed; innovation is defined as the process by which new knowledge is generated and applied in the material and intellectual operations of society. Effects on innovation of the changing economic…

Diagnosing Organizational Innovation: Measuring the Capacity for Innovation

ERIC Educational Resources Information Center

Cropley, David H.; Cropley, Arthur J.; Chiera, Belinda A.; Kaufman, James C.

2013-01-01

Organizational innovation involves reconciling many contradictions or paradoxes. Dividing the process of innovation into phases ranging from Activation to Validation and examining each phase in terms of the six Ps of creativity offers a framework for making sense of these contradictions. The Innovation Phase Assessment Instrument (IPAI) was…

Research on TRIZ and CAIs Application Problems for Technology Innovation

NASA Astrophysics Data System (ADS)

Li, Xiangdong; Li, Qinghai; Bai, Zhonghang; Geng, Lixiao

In order to realize application of invent problem solve theory (TRIZ) and computer aided innovation software (CAIs) , need to solve some key problems, such as the mode choice of technology innovation, establishment of technology innovation organization network(TION), and achievement of innovative process based on TRIZ and CAIs, etc.. This paper shows that the demands for TRIZ and CAIs according to the characteristics and existing problem of the manufacturing enterprises. Have explained that the manufacturing enterprises need to set up an open TION of enterprise leading type, and achieve the longitudinal cooperation innovation with institution of higher learning. The process of technology innovation based on TRIZ and CAIs has been set up from researching and developing point of view. Application of TRIZ and CAIs in FY Company has been summarized. The application effect of TRIZ and CAIs has been explained using technology innovation of the close goggle valve product.

Proof of concept for a new energy-positive wastewater treatment scheme.

PubMed

Remy, C; Boulestreau, M; Lesjean, B

2014-01-01

For improved exploitation of the energy content present in the organic matter of raw sewage, an innovative concept for treatment of municipal wastewater is tested in pilot trials and assessed in energy balance and operational costs. The concept is based on a maximum extraction of organic matter into the sludge via coagulation, flocculation and microsieving (100 μm mesh size) to increase the energy recovery in anaerobic sludge digestion and decrease aeration demand for carbon mineralisation. Pilot trials with real wastewater yield an extraction of 70-80% of total chemical oxygen demand into the sludge while dosing 15-20 mg/L Al and 5-7 mg/L polymer with stable operation of the microsieve and effluent limits below 2-3 mg/L total phosphorus. Anaerobic digestion of the microsieve sludge results in high biogas yields of 600 NL/kg organic dry matter input (oDMin) compared to 430 NL/kg oDMin for mixed sludge from a conventional activated sludge process. The overall energy balance for a 100,000 population equivalent (PE) treatment plant (including biofilter for post-treatment with full nitrification and denitrification with external carbon source) shows that the new concept is an energy-positive treatment process with comparable effluent quality than conventional processes, even when including energy demand for chemicals production. Estimated operating costs for electricity and chemicals are in the same range for conventional activated sludge processes and the new concept.

Quantum nondemolition measurement of the Werner state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin Jiasen; Yu Changshui; Pei Pei

2010-10-15

We propose a theoretical scheme of quantum nondemolition measurement of two-qubit Werner state. We discuss our scheme with the two qubits restricted in a local place and then extend the scheme to the case in which two qubits are separated. We also consider the experimental realization of our scheme based on cavity quantum electrodynamics. It is very interesting that our scheme is robust against the dissipative effects introduced by the probe process. We also give a brief interpretation of our scheme finally.

From stochastic processes to numerical methods: A new scheme for solving reaction subdiffusion fractional partial differential equations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Angstmann, C.N.; Donnelly, I.C.; Henry, B.I., E-mail: B.Henry@unsw.edu.au

We have introduced a new explicit numerical method, based on a discrete stochastic process, for solving a class of fractional partial differential equations that model reaction subdiffusion. The scheme is derived from the master equations for the evolution of the probability density of a sum of discrete time random walks. We show that the diffusion limit of the master equations recovers the fractional partial differential equation of interest. This limiting procedure guarantees the consistency of the numerical scheme. The positivity of the solution and stability results are simply obtained, provided that the underlying process is well posed. We also showmore » that the method can be applied to standard reaction–diffusion equations. This work highlights the broader applicability of using discrete stochastic processes to provide numerical schemes for partial differential equations, including fractional partial differential equations.« less

Biodesign process and culture to enable pediatric medical technology innovation.

PubMed

Wall, James; Wynne, Elizabeth; Krummel, Thomas

2015-06-01

Innovation is the process through which new scientific discoveries are developed and promoted from bench to bedside. In an effort to encourage young entrepreneurs in this area, Stanford Biodesign developed a medical device innovation training program focused on need-based innovation. The program focuses on teaching systematic evaluation of healthcare needs, invention, and concept development. This process can be applied to any field of medicine, including Pediatric Surgery. Similar training programs have gained traction throughout the United States and beyond. Equally important to process in the success of these programs is an institutional culture that supports transformative thinking. Key components of this culture include risk tolerance, patience, encouragement of creativity, management of conflict, and networking effects. Copyright © 2015 Elsevier Inc. All rights reserved.

Enterprise Networks for Competences Exchange: A Simulation Model

NASA Astrophysics Data System (ADS)

Remondino, Marco; Pironti, Marco; Pisano, Paola

A business process is a set of logically related tasks performed to achieve a defined business and related to improving organizational processes. Process innovation can happen at various levels: incrementally, redesign of existing processes, new processes. The knowledge behind process innovation can be shared, acquired, changed and increased by the enterprises inside a network. An enterprise can decide to exploit innovative processes it owns, thus potentially gaining competitive advantage, but risking, in turn, that other players could reach the same technological levels. Or it could decide to share it, in exchange for other competencies or money. These activities could be the basis for a network formation and/or impact the topology of an existing network. In this work an agent based model is introduced (E3), aiming to explore how a process innovation can facilitate network formation, affect its topology, induce new players to enter the market and spread onto the network by being shared or developed by new players.

Differentiating innovation priorities among stakeholder in hospital care.

PubMed

Lambooij, Mattijs S; Hummel, Marjan J

2013-08-16

Decisions to adopt a particular innovation may vary between stakeholders because individual stakeholders may disagree on the costs and benefits involved. This may translate to disagreement between stakeholders on priorities in the implementation process, possibly explaining the slow diffusion of innovations in health care. In this study, we explore the differences in stakeholder preferences for innovations, and quantify the difference in stakeholder priorities regarding costs and benefits. The decision support technique called the analytic hierarchy process was used to quantify the preferences of stakeholders for nine information technology (IT) innovations in hospital care. The selection of the innovations was based on a literature review and expert judgments. Decision criteria related to the costs and benefits of the innovations were defined. These criteria were improvement in efficiency, health gains, satisfaction with care process, and investments required. Stakeholders judged the importance of the decision criteria and subsequently prioritized the selected IT innovations according to their expectations of how well the innovations would perform for these decision criteria. The stakeholder groups (patients, nurses, physicians, managers, health care insurers, and policy makers) had different preference structures for the innovations selected. For instance, self-tests were one of the innovations most preferred by health care insurers and managers, owing to their expected positive impacts on efficiency and health gains. However, physicians, nurses and patients strongly doubted the health gains of self-tests, and accordingly ranked self-tests as the least-preferred innovation. The various stakeholder groups had different expectations of the value of the nine IT innovations. The differences are likely due to perceived stakeholder benefits of each innovation, and less to the costs to individual stakeholder groups. This study provides a first exploratory quantitative insight into stakeholder positions concerning innovation in health care, and presents a novel way to study differences in stakeholder preferences. The results may be taken into account by decision makers involved in the implementation of innovations.

Differentiating innovation priorities among stakeholder in hospital care

PubMed Central

2013-01-01

Background Decisions to adopt a particular innovation may vary between stakeholders because individual stakeholders may disagree on the costs and benefits involved. This may translate to disagreement between stakeholders on priorities in the implementation process, possibly explaining the slow diffusion of innovations in health care. In this study, we explore the differences in stakeholder preferences for innovations, and quantify the difference in stakeholder priorities regarding costs and benefits. Methods The decision support technique called the analytic hierarchy process was used to quantify the preferences of stakeholders for nine information technology (IT) innovations in hospital care. The selection of the innovations was based on a literature review and expert judgments. Decision criteria related to the costs and benefits of the innovations were defined. These criteria were improvement in efficiency, health gains, satisfaction with care process, and investments required. Stakeholders judged the importance of the decision criteria and subsequently prioritized the selected IT innovations according to their expectations of how well the innovations would perform for these decision criteria. Results The stakeholder groups (patients, nurses, physicians, managers, health care insurers, and policy makers) had different preference structures for the innovations selected. For instance, self-tests were one of the innovations most preferred by health care insurers and managers, owing to their expected positive impacts on efficiency and health gains. However, physicians, nurses and patients strongly doubted the health gains of self-tests, and accordingly ranked self-tests as the least-preferred innovation. Conclusions The various stakeholder groups had different expectations of the value of the nine IT innovations. The differences are likely due to perceived stakeholder benefits of each innovation, and less to the costs to individual stakeholder groups. This study provides a first exploratory quantitative insight into stakeholder positions concerning innovation in health care, and presents a novel way to study differences in stakeholder preferences. The results may be taken into account by decision makers involved in the implementation of innovations. PMID:23947398

New, Improved Goddard Bulk-Microphysical Schemes for Studying Precipitation Processes in WRF

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2007-01-01

An improved bulk microphysical parameterization is implemented into the Weather Research and Forecasting ()VRF) model. This bulk microphysical scheme has three different options, 2ICE (cloud ice & snow), 3ICE-graupel (cloud ice, snow & graupel) and 3ICE-hail (cloud ice, snow & hail). High-resolution model simulations are conducted to examine the impact of microphysical schemes on two different weather events (a midlatitude linear convective system and an Atlantic hurricane). The results suggest that microphysics has a major impact on the organization and precipitation processes associated with a summer midlatitude convective line system. The Goddard 3ICE scheme with a cloud ice-snow-hail configuration agreed better with observations in terms of rainfall intensity and a narrow convective line than did simulations with a cloud ice-snow-graupel or cloud ice-snow (i.e., 2ICE) configuration. This is because the 3ICE-hail scheme includes dense ice precipitating (hail) particle with very fast fall speed (over 10 in For an Atlantic hurricane case, the Goddard microphysical schemes had no significant impact on the track forecast but did affect the intensity slightly. The improved Goddard schemes are also compared with WRF's three other 3ICE bulk microphysical schemes: WSM6, Purdue-Lin and Thompson. For the summer midlatitude convective line system, all of the schemes resulted in simulated precipitation events that were elongated in the southwest-northeast direction in qualitative agreement with the observed feature. However, the Goddard 3ICE scheme with the hail option and the Thompson scheme agree better with observations in terms of rainfall intensity, expect that the Goddard scheme simulated more heavy rainfall (over 48 mm/h). For the Atlantic hurricane case, none of the schemes had a significant impact on the track forecast; however, the simulated intensity using the Purdue-Lin scheme was much stronger than the other schemes. The vertical distributions of model simulated cloud species (i.e., snow) are quite sensitive to microphysical schemes, which is an important issue for future verification against satellite retrievals. Both the Purdue-Lin and WSM6 schemes simulated very little snow compared to the other schemes for both the midlatitude convective line and hurricane cases. Sensitivity tests are performed for these two WRF schemes to identify that snow productions could be increased by increasing the snow intercept, turning off the auto-conversion from snow to graupel and reducing the transfer processes from cloud-sized particles to precipitation-sized ice.

Innovation in urban agriculture: Evaluation data of a participatory approach (ROIR).

PubMed

Zoll, Felix; Specht, Kathrin; Siebert, Rosemarie

2016-06-01

The data in this article represent an evaluation of a participatory process called Regional Open Innovation Roadmapping (ROIR). The approach aims at the promotion of regional development. In this case, it was carried out to develop a specific innovation in the field of 'Zero-acreage farming' (ZFarming), which is a building-related subtype of urban agriculture. For the evaluation of the process, an online survey was sent to the 58 participants of the ROIR on March 4, 2014. The survey ended on April 8, 2014, and a response rate of 53.54% resulted in a sample size of 31 respondents. The survey was divided into seven different blocks. We analyzed the ROIR process׳s contribution to knowledge generation, the establishment of networks among the participants, the implementation of new projects related to ZFarming, and the increase of acceptance of ZFarming and the selected ZFarming innovation. Furthermore, other remarks, and personal information were collected. Hence, the objective of the survey was to assess whether ROIR is a useful tool to promote the aforementioned innovation drivers, and thereby, the selected innovation, which was developed throughout the process. The data were used in the research article "Application and evaluation of a participatory "open innovation" approach (ROIR): the case of introducing zero-acreage farming in Berlin" (Specht et al., 2016) [1].

Applying circular economy innovation theory in business process modeling and analysis

NASA Astrophysics Data System (ADS)

Popa, V.; Popa, L.

2017-08-01

The overall aim of this paper is to develop a new conceptual framework for business process modeling and analysis using circular economy innovative theory as a source for business knowledge management. The last part of the paper presents an author’s proposed basic structure for a new business models applying circular economy innovation theories. For people working on new innovative business models in the field of the circular economy this paper provides new ideas for clustering their concepts.

TEXACO GASIFICATION PROCESS - INNOVATIVE TECHNOLOGY EVALUATION REPORT

EPA Science Inventory

This report summarizes the evaluation of the Texaco Gasification Process (TGP) conducted under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The Texaco Gasification Process was developed by Texaco Inc. The TGP is a comm...

Fuel quality/processing study. Volume 3: Fuel upgrading studies

NASA Technical Reports Server (NTRS)

Jones, G. E., Jr.; Bruggink, P.; Sinnett, C.

1981-01-01

The methods used to calculate the refinery selling prices for the turbine fuels of low quality are described. Detailed descriptions and economics of the upgrading schemes are included. These descriptions include flow diagrams showing the interconnection between processes and the stream flows involved. Each scheme is in a complete, integrated, stand alone facility. Except for the purchase of electricity and water, each scheme provides its own fuel and manufactures, when appropriate, its own hydrogen.

Innovative teaching methods for capacity building in knowledge translation

PubMed Central

2011-01-01

Background In some current healthcare settings, there is a noticeable absence of national institutions committed to the synthesis and use of evidence in healthcare decision- and policy-making. This absence creates a need to broaden the responsibilities of healthcare providers to include knowledge brokering and advocacy in order to optimize knowledge translation to other stakeholders, especially policy-makers. However, this process requires practitioners and researchers to acquire certain types of knowledge and skills. This article introduces two innovative methods for capacity building in knowledge translation (KT). Methods During a workshop aimed at preparing 21 trainers in evidence-based medicine, two innovative methods were used: (1) debate and (2) a knowledge translation project (KTP). The main objective of the debates approach was to strengthen participants' critical thinking abilities by requiring them to search for and appraise evidence and defend their arguments. The KTP was used to introduce participants to the essential steps of knowledge translation and to suggest an extended role for healthcare practitioners, i.e., using evidence to manage not only individual patients but also to a community of patients. Participants' performances were assessed according to a pre-designed scheme. At the end of the workshop, participants' opinions and experiences with the innovative teaching methods were evaluated based on their answers to a questionnaire and the results of small-group discussions. Results The participants performed well in both the debate and KTP methods. During post-workshop group discussions, they indicated that the debate approach had added a new dimension to their evidence-based medicine skills by adding purpose and motivation. However, they felt that their performances would have been better if they had been offered practical demonstrations of how to conduct the debate. The participants indicated that the KTP enhanced their understanding of the relationships between evidence and implementation, and motivated them to investigate public health problems in addition to individual patient problems. However, some participants maintained that these issues fell outside the scope of their role as doctors. Conclusion Debates and evidence implementation through KTP are generally well accepted by healthcare practitioners as methods by which they can improve their skills in KT. PMID:21999174

Innovative teaching methods for capacity building in knowledge translation.

PubMed

Wahabi, Hayfaa A; Al-Ansary, Lubna A

2011-10-14

In some current healthcare settings, there is a noticeable absence of national institutions committed to the synthesis and use of evidence in healthcare decision- and policy-making. This absence creates a need to broaden the responsibilities of healthcare providers to include knowledge brokering and advocacy in order to optimize knowledge translation to other stakeholders, especially policy-makers. However, this process requires practitioners and researchers to acquire certain types of knowledge and skills. This article introduces two innovative methods for capacity building in knowledge translation (KT). During a workshop aimed at preparing 21 trainers in evidence-based medicine, two innovative methods were used: (1) debate and (2) a knowledge translation project (KTP). The main objective of the debates approach was to strengthen participants' critical thinking abilities by requiring them to search for and appraise evidence and defend their arguments. The KTP was used to introduce participants to the essential steps of knowledge translation and to suggest an extended role for healthcare practitioners, i.e., using evidence to manage not only individual patients but also to a community of patients. Participants' performances were assessed according to a pre-designed scheme. At the end of the workshop, participants' opinions and experiences with the innovative teaching methods were evaluated based on their answers to a questionnaire and the results of small-group discussions. The participants performed well in both the debate and KTP methods. During post-workshop group discussions, they indicated that the debate approach had added a new dimension to their evidence-based medicine skills by adding purpose and motivation. However, they felt that their performances would have been better if they had been offered practical demonstrations of how to conduct the debate. The participants indicated that the KTP enhanced their understanding of the relationships between evidence and implementation, and motivated them to investigate public health problems in addition to individual patient problems. However, some participants maintained that these issues fell outside the scope of their role as doctors. Debates and evidence implementation through KTP are generally well accepted by healthcare practitioners as methods by which they can improve their skills in KT.

The Relationship between Individual Innovativeness and Psychological Well-Being: The Example of Turkish Counselor Trainees

ERIC Educational Resources Information Center

Ikiz, Fatma Ebru; Asici, Esra

2017-01-01

In this study, we handled psychological well-being (PWB) and individual innovativeness (IND-INO) as personality qualities which an effective counselor needs to possess to meet the expectancies of clients in new era. Moreover, we tried to figure out (1) the similarities between counseling process and innovativeness process and (2) the congruency…

Interactions of Science and Technology in the Innovative Process: Some Case Studies. Final Report.

ERIC Educational Resources Information Center

Battelle Memorial Inst., Columbus, OH. Columbus Labs.

This is the final report of the latest effort in a series sponsored by the National Science Foundation on the innovation process. It adds to the store of retrospective case studies by documenting historically the significant events in several technological innovations of high social impact. These cases, drawn together by the Battelle Columbus…

The why, what, and how of management innovation.

PubMed

Hamel, Gary

2006-02-01

For organizations like GE, P&G, and Visa, management innovation is the secret to success. But what is management innovation? Why is it so important? And how can other companies learn to become management innovators? This article from expert Gary Hamel answers those questions. A management breakthrough can deliver a strong advantage to the innovating company and produce a major shift in industry leadership. Few companies, however, have been able to come up with a formal process for fostering management innovation. The biggest challenge seems to be generating truly unique ideas. Four components can help: a big problem that demands fresh thinking, creative principles or paradigms that can reveal new approaches, an evaluation of the conventions that constrain novel thinking, and examples and analogies that help redefine what can be done. No doubt there are existing management processes in your organization that exacerbate the big problems you're hoping to solve. So how can you learn to identify them? Start by asking a series of questions for each one. For instance, Who owns the process? What are its objectives? What are the metrics for success? What are the decision-making criteria? How are decisions communicated, and to whom? After documenting these details, ask the people involved with the process to weigh in. This exploration may reveal opportunities to reinventyour management processes. A management innovation, the author says, creates long-lasting advantage when it meets at least one of three conditions: It is based on a novel principle that challenges the orthodoxy; it is systemic, involving a range of processes and methods; or it is part of a program of invention, where progress compounds over time. So far, management in this century isn't much different from management in the previous one, says Hamel. Therein lies the opportunity. You can wait for a competitor to come upon the next great management process and drive you out of business-or you can become a management innovator right now.

What Does an Inventory of Recent Innovation Experiences Tell Us about Agricultural Innovation in Africa?

ERIC Educational Resources Information Center

Triomphe, Bernard; Floquet, Anne; Kamau, Geoffrey; Letty, Brigid; Vodouhe, Simplice Davo; Ng'ang'a, Teresiah; Stevens, Joe; van den Berg, Jolanda; Selemna, Nour; Bridier, Bernard; Crane, Todd; Almekinders, Cornelia; Waters-Bayer, Ann; Hocde, Henri

2013-01-01

Purpose: Within the context of the European-funded JOLISAA project (JOint Learning in and about Innovation Systems in African Agriculture), an inventory of agricultural innovation experiences was made in Benin, Kenya and South Africa. The objective was to assess multi-stakeholder agricultural innovation processes involving smallholders. Approach:…

Procedures for Managing Innovations. Analysis of Literature and Selected Bibliography. Analysis and Bibliography Series, No. 7.

ERIC Educational Resources Information Center

ERIC Clearinghouse on Educational Management, Eugene, OR.

This rview focuses on the innovation process in local schools. Emphasis is placed on (1) how local schools implement innovations, (2) facilitators and inhibitors of innovation, and (3) unmet needs in assisting schools to adopt innovations. A 78-item bibliography of rlated literature is included. (RA)

Engineering Encounters: The Tightrope Challenge

ERIC Educational Resources Information Center

Burton, Bill

2014-01-01

In order to prepare students to become the next innovators, teachers need to provide real-world challenges that allow children to exercise their innovation muscles. Innovation starts with a problem and innovators work to solve a problem by planning, creating, and testing. The real-world innovation process does not happen on a worksheet, and it…

Six Thinking Hats and Social Workers' Innovative Competence: An Experimental Study

ERIC Educational Resources Information Center

Azeez, Razaq Olugbenga

2016-01-01

Employees, no doubt, are the main force in organizations, and their innovative behaviours are vital for outcome efficacy. Innovative organisations, therefore, need creative employees who generate new ideas for product or process of innovation. This study investigated the effect of six thinking hats creativity technique on innovative competence of…

Empower: access to medicine - working towards early access.

PubMed

Pearson, Jennifer Bryant; Turgoose, James; Hargrave, James

2015-01-01

Empower: Access to Medicine's contribution will document the founding of Empower: Access to Medicine and tactics used to create a lobbying campaign designed to facilitate the debate around barriers to medical innovation and patient access to medicines. The article will detail the evolution of the campaign's goals and the potential solutions to an expensive and slow system. Specifically the submission will look at the influence that Empower: Access to Medicine had on the Government's thinking and development of an early access scheme.

Modeling of the Nonlinear Interface in Reinforced Concrete

NASA Astrophysics Data System (ADS)

Curiel Sosa, J. L.

2010-04-01

This article presents a novel scheme for modeling of reinforced concrete. The strategy takes into account the nonlinear behavior of the concrete as well as the debonding in the interface. The proposed technique solves the kinematic and kinetic jump in the interface by performing sub-cycles over the constituents-reinforcing bar and concrete-jointly with an innovative interface constitutive law. Application to pull-out problems is performed to show the capabilities of the proposed methodology by means of comparison with available experimental data.

Gravitational Wave Detection with Single-Laser Atom Interferometers

NASA Technical Reports Server (NTRS)

Yu, Nan; Tinto, Massimo

2011-01-01

A new design for a broadband detector of gravitational radiation relies on two atom interferometers separated by a distance L. In this scheme, only one arm and one laser are used for operating the two atom interferometers. The innovation here involves the fact that the atoms in the atom interferometers are not only considered as perfect test masses, but also as highly stable clocks. Atomic coherence is intrinsically stable, and can be many orders of magnitude more stable than a laser.

Grand challenges in mass storage: A system integrator's perspective

NASA Technical Reports Server (NTRS)

Mintz, Dan; Lee, Richard

1993-01-01

The grand challenges are the following: to develop more innovation in approach; to expand the I/O barrier; to achieve increased volumetric efficiency and incremental cost improvements; to reinforce the 'weakest link' software; to implement improved architectures; and to minimize the impact of self-destructing technologies. Mass storage is defined as any type of storage system exceeding 100 GBytes in total size, under the control of a centralized file management scheme. The topics covered are presented in viewgraph form.

Accumulate Repeat Accumulate Coded Modulation

NASA Technical Reports Server (NTRS)

Abbasfar, Aliazam; Divsalar, Dariush; Yao, Kung

2004-01-01

In this paper we propose an innovative coded modulation scheme called 'Accumulate Repeat Accumulate Coded Modulation' (ARA coded modulation). This class of codes can be viewed as serial turbo-like codes, or as a subclass of Low Density Parity Check (LDPC) codes that are combined with high level modulation. Thus at the decoder belief propagation can be used for iterative decoding of ARA coded modulation on a graph, provided a demapper transforms the received in-phase and quadrature samples to reliability of the bits.

Optical trapping

PubMed Central

Neuman, Keir C.; Block, Steven M.

2006-01-01

Since their invention just over 20 years ago, optical traps have emerged as a powerful tool with broad-reaching applications in biology and physics. Capabilities have evolved from simple manipulation to the application of calibrated forces on—and the measurement of nanometer-level displacements of—optically trapped objects. We review progress in the development of optical trapping apparatus, including instrument design considerations, position detection schemes and calibration techniques, with an emphasis on recent advances. We conclude with a brief summary of innovative optical trapping configurations and applications. PMID:16878180

Femtosecond pulses propagation through pure water

NASA Astrophysics Data System (ADS)

Naveira, Lucas; Sokolov, Alexei; Byeon, Joong-Hyeok; Kattawar, George

2007-10-01

Recently, considerable attention has been dedicated to the field of optical precursors, which can possibly be applied to long-distance underwater communications. Input beam intensities have been carefully adjusted to keep experiments in the linear regime, and some experiments have shown violation of the Beer-Lambert law. We are presently carrying out experiments using femtosecond laser pulses propagating through pure water strictly in the linear regime to study this interesting and important behavior. We are also employing several new and innovative schemes to more clearly define the phenomena.

[Reform and practice of teaching methods for culture of medicinal plant].

PubMed

Si, Jinping; Zhu, Yuqiu; Liu, Jingjing; Bai, Yan; Zhang, Xinfeng

2012-02-01

Culture of pharmaceutical plant is a comprehensive multi-disciplinary theory, which has a long history of application. In order to improve the quality of this course, some reformation schemes have been carried out, including stimulating enthusiasm for learning, refining the basic concepts and theories, promoting the case study, emphasis on latest achievements, enhancing exercise in laboratory and planting base, and guiding students to do scientific and technological innovation. Meanwhile, the authors point out some teaching problems of this course.

[Development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry].

PubMed

Xiao, Yong-Qing; Li, Li; Liu, Ying; Ma, Yin-Lian; Yu, Ding-Rong

2016-01-01

To elucidate the key issues in the development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry Chinese herbal pieces industry. According to the author's accumulated experience over years and demand of the development of the Chinese herbal pieces industry, the key issues in the development and innovation on the Chinese herbal pieces industry were summarized. According to the author, the traditional Chinese medicine processing discipline shall focus on a application basis research. The development of this discipline should be closely related to the development of Chinese herbal pieces. The traditional Chinese medicine processing discipline can be improved and its results can be transformed only if this discipline were correlated with the Chinese herbal pieces industry, matched with the development of the Chinese herbal pieces industry, and solved the problems in the development on the Chinese herbal pieces industry. The development of traditional Chinese medicine processing discipline and the Chinese herbal pieces industry also requires scientific researchers to make constant innovations, realize the specialty of the researches, and innovate based on inheritance. Copyright© by the Chinese Pharmaceutical Association.

Studying Precipitation Processes in WRF with Goddard Bulk Microphysics in Comparison with Other Microphysical Schemes

NASA Technical Reports Server (NTRS)

Tao, W.K.; Shi, J.J.; Braun, S.; Simpson, J.; Chen, S.S.; Lang, S.; Hong, S.Y.; Thompson, G.; Peters-Lidard, C.

2009-01-01

A Goddard bulk microphysical parameterization is implemented into the Weather Research and Forecasting (WRF) model. This bulk microphysical scheme has three different options, 2ICE (cloud ice & snow), 3ICE-graupel (cloud ice, snow & graupel) and 3ICE-hail (cloud ice, snow & hail). High-resolution model simulations are conducted to examine the impact of microphysical schemes on different weather events: a midlatitude linear convective system and an Atlantic hurricane. The results suggest that microphysics has a major impact on the organization and precipitation processes associated with a summer midlatitude convective line system. The Goddard 3ICE scheme with the cloud ice-snow-hail configuration agreed better with observations ill of rainfall intensity and having a narrow convective line than did simulations with the cloud ice-snow-graupel and cloud ice-snow (i.e., 2ICE) configurations. This is because the Goddard 3ICE-hail configuration has denser precipitating ice particles (hail) with very fast fall speeds (over 10 m/s) For an Atlantic hurricane case, the Goddard microphysical scheme (with 3ICE-hail, 3ICE-graupel and 2ICE configurations) had no significant impact on the track forecast but did affect the intensity slightly. The Goddard scheme is also compared with WRF's three other 3ICE bulk microphysical schemes: WSM6, Purdue-Lin and Thompson. For the summer midlatitude convective line system, all of the schemes resulted in simulated precipitation events that were elongated in southwest-northeast direction in qualitative agreement with the observed feature. However, the Goddard 3ICE-hail and Thompson schemes were closest to the observed rainfall intensities although the Goddard scheme simulated more heavy rainfall (over 48 mm/h). For the Atlantic hurricane case, none of the schemes had a significant impact on the track forecast; however, the simulated intensity using the Purdue-Lin scheme was much stronger than the other schemes. The vertical distributions of model-simulated cloud species (e.g., snow) are quite sensitive to the microphysical schemes, which is an issue for future verification against satellite retrievals. Both the Purdue-Lin and WSM6 schemes simulated very little snow compared to the other schemes for both the midlatitude convective line and hurricane case. Sensitivity tests with these two schemes showed that increasing the snow intercept, turning off the auto-conversion from snow to graupel, eliminating dry growth, and reducing the transfer processes from cloud-sized particles to precipitation-sized ice collectively resulted in a net increase in those schemes' snow amounts.

COGNIS TERRAMET® LEAD EXTRACTION PROCESS; INNOVATIVE TECHNOLOGY EVALUATION REPORT

EPA Science Inventory

This report documents an evaluation of lead removal from sands and fines fractions of contaminated soils by the COGNIS TERRAMET® lead extraction process (COGNIS process). The evaluation was performed under the U.S. Environmental Protection Agency's Superfund Innovative Technolog...

Unmet needs: relevance to medical technology innovation?

PubMed

McCarthy, Avril D; Sproson, Lise; Wells, Oliver; Tindale, Wendy

2014-01-01

This paper describes and discusses the role of unmet needs in the innovation of new medical technologies using the National Institute for Health Research Devices for Dignity (D4D) Healthcare Technology Co-operative as a case study. It defines an unmet need, providing a spectrum of classification and discusses the benefits and the challenges of identifying unmet need and its influence on the innovation process. The process by which D4D has captured and utilized unmet needs to drive technology innovation is discussed and examples given. It concludes by arguing that, despite the challenges, defining and reviewing unmet need is a fundamental factor in the success of medical technology innovation.

A Novel Protective Framework for Defeating HTTP-Based Denial of Service and Distributed Denial of Service Attacks.

PubMed

Saleh, Mohammed A; Abdul Manaf, Azizah

2015-01-01

The growth of web technology has brought convenience to our life, since it has become the most important communication channel. However, now this merit is threatened by complicated network-based attacks, such as denial of service (DoS) and distributed denial of service (DDoS) attacks. Despite many researchers' efforts, no optimal solution that addresses all sorts of HTTP DoS/DDoS attacks is on offer. Therefore, this research aims to fix this gap by designing an alternative solution called a flexible, collaborative, multilayer, DDoS prevention framework (FCMDPF). The innovative design of the FCMDPF framework handles all aspects of HTTP-based DoS/DDoS attacks through the following three subsequent framework's schemes (layers). Firstly, an outer blocking (OB) scheme blocks attacking IP source if it is listed on the black list table. Secondly, the service traceback oriented architecture (STBOA) scheme is to validate whether the incoming request is launched by a human or by an automated tool. Then, it traces back the true attacking IP source. Thirdly, the flexible advanced entropy based (FAEB) scheme is to eliminate high rate DDoS (HR-DDoS) and flash crowd (FC) attacks. Compared to the previous researches, our framework's design provides an efficient protection for web applications against all sorts of DoS/DDoS attacks.

A Novel Protective Framework for Defeating HTTP-Based Denial of Service and Distributed Denial of Service Attacks

PubMed Central

Saleh, Mohammed A.; Abdul Manaf, Azizah

2015-01-01

The growth of web technology has brought convenience to our life, since it has become the most important communication channel. However, now this merit is threatened by complicated network-based attacks, such as denial of service (DoS) and distributed denial of service (DDoS) attacks. Despite many researchers' efforts, no optimal solution that addresses all sorts of HTTP DoS/DDoS attacks is on offer. Therefore, this research aims to fix this gap by designing an alternative solution called a flexible, collaborative, multilayer, DDoS prevention framework (FCMDPF). The innovative design of the FCMDPF framework handles all aspects of HTTP-based DoS/DDoS attacks through the following three subsequent framework's schemes (layers). Firstly, an outer blocking (OB) scheme blocks attacking IP source if it is listed on the black list table. Secondly, the service traceback oriented architecture (STBOA) scheme is to validate whether the incoming request is launched by a human or by an automated tool. Then, it traces back the true attacking IP source. Thirdly, the flexible advanced entropy based (FAEB) scheme is to eliminate high rate DDoS (HR-DDoS) and flash crowd (FC) attacks. Compared to the previous researches, our framework's design provides an efficient protection for web applications against all sorts of DoS/DDoS attacks. PMID:26065015

Dynamics of moment neuronal networks.

PubMed

Feng, Jianfeng; Deng, Yingchun; Rossoni, Enrico

2006-04-01

A theoretical framework is developed for moment neuronal networks (MNNs). Within this framework, the behavior of the system of spiking neurons is specified in terms of the first- and second-order statistics of their interspike intervals, i.e., the mean, the variance, and the cross correlations of spike activity. Since neurons emit and receive spike trains which can be described by renewal--but generally non-Poisson--processes, we first derive a suitable diffusion-type approximation of such processes. Two approximation schemes are introduced: the usual approximation scheme (UAS) and the Ornstein-Uhlenbeck scheme. It is found that both schemes approximate well the input-output characteristics of spiking models such as the IF and the Hodgkin-Huxley models. The MNN framework is then developed according to the UAS scheme, and its predictions are tested on a few examples.

Statistical process control based chart for information systems security

NASA Astrophysics Data System (ADS)

Khan, Mansoor S.; Cui, Lirong

2015-07-01

Intrusion detection systems have a highly significant role in securing computer networks and information systems. To assure the reliability and quality of computer networks and information systems, it is highly desirable to develop techniques that detect intrusions into information systems. We put forward the concept of statistical process control (SPC) in computer networks and information systems intrusions. In this article we propose exponentially weighted moving average (EWMA) type quality monitoring scheme. Our proposed scheme has only one parameter which differentiates it from the past versions. We construct the control limits for the proposed scheme and investigate their effectiveness. We provide an industrial example for the sake of clarity for practitioner. We give comparison of the proposed scheme with EWMA schemes and p chart; finally we provide some recommendations for the future work.

Early Patient Access to Medicines: Health Technology Assessment Bodies Need to Catch Up with New Marketing Authorization Methods.

PubMed

Leyens, Lada; Brand, Angela

National and international medicines agencies have developed innovative methods to expedite promising new medicines to the market and facilitate early patient access. Some of these approval pathways are the conditional approval and the adaptive pathways by the European Medicines Agency (EMA); the Promising Innovative Medicine (PIM) designation and the Early Access to Medicines Scheme (EAMS) by the Medicines and Healthcare Products Regulatory Agency (MHRA), as well as the Fast Track, Breakthrough or Accelerated Approval methods by the Food and Drug Administration (FDA). However, at least in Europe, these methods cannot achieve the goal of improving timely access for patients to new medicines on their own; the reimbursement process also has to become adaptive and flexible. In the past 2 years, the effective access (national patient access) to newly approved oncology drugs ranged from 1 to 30 months, with an extremely high variability between European countries. The goal of early patient access in Europe can only be achieved if the national health technology assessment bodies, such as NICE (ENG), HAS (FR), G-BA (DE) or AIFA (IT), provide harmonized, transparent, flexible, conditional and adaptive methods that adopt the level of evidence accepted by the medicines agencies. The efforts from medicines agencies are welcome but will be in vain if health technology assessments do not follow with similar initiatives, and the European 'postcode' lottery will continue. © 2016 S. Karger AG, Basel.

Comparison of the Tangent Linear Properties of Tracer Transport Schemes Applied to Geophysical Problems.

NASA Technical Reports Server (NTRS)

Kent, James; Holdaway, Daniel

2015-01-01

A number of geophysical applications require the use of the linearized version of the full model. One such example is in numerical weather prediction, where the tangent linear and adjoint versions of the atmospheric model are required for the 4DVAR inverse problem. The part of the model that represents the resolved scale processes of the atmosphere is known as the dynamical core. Advection, or transport, is performed by the dynamical core. It is a central process in many geophysical applications and is a process that often has a quasi-linear underlying behavior. However, over the decades since the advent of numerical modelling, significant effort has gone into developing many flavors of high-order, shape preserving, nonoscillatory, positive definite advection schemes. These schemes are excellent in terms of transporting the quantities of interest in the dynamical core, but they introduce nonlinearity through the use of nonlinear limiters. The linearity of the transport schemes used in Goddard Earth Observing System version 5 (GEOS-5), as well as a number of other schemes, is analyzed using a simple 1D setup. The linearized version of GEOS-5 is then tested using a linear third order scheme in the tangent linear version.

Darwin and the demon: innovating within established enterprises.

PubMed

Moore, Geoffrey A

2004-01-01

As commercial processes commoditize in a developed economy, they are outsourced or transferred offshore, leaving onshore companies with unrelenting, Darwinian pressure to come up with the next wave of innovation. But innovation is a broad term. There are many types, from the ballyhooed disruptive innovation to more mundane forms such as process and experiential, which might involve, respectively, doing such things as streamlining the supply chain and delighting customers with small modifications of products. Many executives find it hard to decide which kind to focus on. The best way to choose is to consider the phases of a market's life span. In a market's earliest phase, a new technology attracts enthusiasts and visionaries. Eventually, the market reaches the Main Street section of its life, when growth slows, flattens, and finally subsides. Different types of innovation produce more bang for the buck at different points in the life cycle. Disruptive innovation, for example, is rewarded most during the earliest phase. Once the life cycle advances to Main Street, however, the marketplace is no longer willing to yield the revenue or margin gains necessary to fund that type of innovation, so other forms, including process and experiential, yield better returns. But attempts to change the company's direction are often thwarted by the inertia that success creates. To overcome the inertia demon, managers must introduce new types of innovation while aggressively extracting resources from legacy processes and organizations. By running the two efforts in parallel, they can defeat the demon and renew the company.

Heterogeneous update mechanisms in evolutionary games: Mixing innovative and imitative dynamics

NASA Astrophysics Data System (ADS)

Amaral, Marco Antonio; Javarone, Marco Alberto

2018-04-01

Innovation and evolution are two processes of paramount relevance for social and biological systems. In general, the former allows the introduction of elements of novelty, while the latter is responsible for the motion of a system in its phase space. Often, these processes are strongly related, since an innovation can trigger the evolution, and the latter can provide the optimal conditions for the emergence of innovations. Both processes can be studied by using the framework of evolutionary game theory, where evolution constitutes an intrinsic mechanism. At the same time, the concept of innovation requires an opportune mathematical representation. Notably, innovation can be modeled as a strategy, or it can constitute the underlying mechanism that allows agents to change strategy. Here, we analyze the second case, investigating the behavior of a heterogeneous population, composed of imitative and innovative agents. Imitative agents change strategy only by imitating that of their neighbors, whereas innovative ones change strategy without the need for a copying source. The proposed model is analyzed by means of analytical calculations and numerical simulations in different topologies. Remarkably, results indicate that the mixing of mechanisms can be detrimental to cooperation near phase transitions. In those regions, the spatial reciprocity from imitative mechanisms is destroyed by innovative agents, leading to the downfall of cooperation. Our investigation sheds some light on the complex dynamics emerging from the heterogeneity of strategy revision methods, highlighting the role of innovation in evolutionary games.

Heterogeneous update mechanisms in evolutionary games: Mixing innovative and imitative dynamics.

PubMed

Amaral, Marco Antonio; Javarone, Marco Alberto

2018-04-01

Innovation and evolution are two processes of paramount relevance for social and biological systems. In general, the former allows the introduction of elements of novelty, while the latter is responsible for the motion of a system in its phase space. Often, these processes are strongly related, since an innovation can trigger the evolution, and the latter can provide the optimal conditions for the emergence of innovations. Both processes can be studied by using the framework of evolutionary game theory, where evolution constitutes an intrinsic mechanism. At the same time, the concept of innovation requires an opportune mathematical representation. Notably, innovation can be modeled as a strategy, or it can constitute the underlying mechanism that allows agents to change strategy. Here, we analyze the second case, investigating the behavior of a heterogeneous population, composed of imitative and innovative agents. Imitative agents change strategy only by imitating that of their neighbors, whereas innovative ones change strategy without the need for a copying source. The proposed model is analyzed by means of analytical calculations and numerical simulations in different topologies. Remarkably, results indicate that the mixing of mechanisms can be detrimental to cooperation near phase transitions. In those regions, the spatial reciprocity from imitative mechanisms is destroyed by innovative agents, leading to the downfall of cooperation. Our investigation sheds some light on the complex dynamics emerging from the heterogeneity of strategy revision methods, highlighting the role of innovation in evolutionary games.

High-Speed Data Acquisition and Digital Signal Processing System for PET Imaging Techniques Applied to Mammography

NASA Astrophysics Data System (ADS)

Martinez, J. D.; Benlloch, J. M.; Cerda, J.; Lerche, Ch. W.; Pavon, N.; Sebastia, A.

2004-06-01

This paper is framed into the Positron Emission Mammography (PEM) project, whose aim is to develop an innovative gamma ray sensor for early breast cancer diagnosis. Currently, breast cancer is detected using low-energy X-ray screening. However, functional imaging techniques such as PET/FDG could be employed to detect breast cancer and track disease changes with greater sensitivity. Furthermore, a small and less expensive PET camera can be utilized minimizing main problems of whole body PET. To accomplish these objectives, we are developing a new gamma ray sensor based on a newly released photodetector. However, a dedicated PEM detector requires an adequate data acquisition (DAQ) and processing system. The characterization of gamma events needs a free-running analog-to-digital converter (ADC) with sampling rates of more than 50 Ms/s and must achieve event count rates up to 10 MHz. Moreover, comprehensive data processing must be carried out to obtain event parameters necessary for performing the image reconstruction. A new generation digital signal processor (DSP) has been used to comply with these requirements. This device enables us to manage the DAQ system at up to 80 Ms/s and to execute intensive calculi over the detector signals. This paper describes our designed DAQ and processing architecture whose main features are: very high-speed data conversion, multichannel synchronized acquisition with zero dead time, a digital triggering scheme, and high throughput of data with an extensive optimization of the signal processing algorithms.

A whole-process progressive training mode to foster optoelectronic students' innovative practical ability

NASA Astrophysics Data System (ADS)

Zhong, Hairong; Xu, Wei; Hu, Haojun; Duan, Chengfang

2017-08-01

This article analyzes the features of fostering optoelectronic students' innovative practical ability based on the knowledge structure of optoelectronic disciplines, which not only reveals the common law of cultivating students' innovative practical ability, but also considers the characteristics of the major: (1) The basic theory is difficult, and the close combination of science and technology is obvious; (2)With the integration of optics, mechanics, electronics and computer, the system technology is comprehensive; (3) It has both leading-edge theory and practical applications, so the benefit of cultivating optoelectronic students is high ; (4) The equipment is precise and the practice is costly. Considering the concept and structural characteristics of innovative and practical ability, and adhering to the idea of running practice through the whole process, we put forward the construction of three-dimensional innovation and practice platform which consists of "Synthetically Teaching Laboratory + Innovation Practice Base + Scientific Research Laboratory + Major Practice Base + Joint Teaching and Training Base", and meanwhile build a whole-process progressive training mode to foster optoelectronic students' innovative practical ability, following the process of "basic experimental skills training - professional experimental skills training - system design - innovative practice - scientific research project training - expanded training - graduation project": (1) To create an in - class practical ability cultivation environment that has distinctive characteristics of the major, with the teaching laboratory as the basic platform; (2) To create an extra-curricular innovation practice activities cultivation environment that is closely linked to the practical application, with the innovation practice base as a platform for improvement; (3) To create an innovation practice training cultivation environment that leads the development of cutting-edge, with the scientific research laboratory as a platform to explore; (4) To create an out-campus expanded training environment of optoelectronic major practice and optoelectronic system teaching and training, with the major practice base as an expansion of the platform; (5) To break students' "pre-job training barriers" between school and work, with graduation design as the comprehensive training and testing link.

Fast Pixel Buffer For Processing With Lookup Tables

NASA Technical Reports Server (NTRS)

Fisher, Timothy E.

1992-01-01

Proposed scheme for buffering data on intensities of picture elements (pixels) of image increases rate or processing beyond that attainable when data read, one pixel at time, from main image memory. Scheme applied in design of specialized image-processing circuitry. Intended to optimize performance of processor in which electronic equivalent of address-lookup table used to address those pixels in main image memory required for processing.

On the stability of the Atlantic meridional overturning circulation.

PubMed

Hofmann, Matthias; Rahmstorf, Stefan

2009-12-08

One of the most important large-scale ocean current systems for Earth's climate is the Atlantic meridional overturning circulation (AMOC). Here we review its stability properties and present new model simulations to study the AMOC's hysteresis response to freshwater perturbations. We employ seven different versions of an Ocean General Circulation Model by using a highly accurate tracer advection scheme, which minimizes the problem of numerical diffusion. We find that a characteristic freshwater hysteresis also exists in the predominantly wind-driven, low-diffusion limit of the AMOC. However, the shape of the hysteresis changes, indicating that a convective instability rather than the advective Stommel feedback plays a dominant role. We show that model errors in the mean climate can make the hysteresis disappear, and we investigate how model innovations over the past two decades, like new parameterizations and mixing schemes, affect the AMOC stability. Finally, we discuss evidence that current climate models systematically overestimate the stability of the AMOC.

Innovative scheme for high-repetition-rate imaging of CN radical.

PubMed

Satija, Aman; Ruesch, Morgan D; Powell, Michael S; Son, Steven F; Lucht, Robert P

2018-02-01

We have employed, to the best of our knowledge, a novel excitation scheme to perform the first high-repetition-rate planar laser-induced fluorescence (PLIF) measurements of a CN radical in combustion. The third harmonic of a Nd:YVO 4 laser at 355 nm due to its relatively large linewidth overlaps with several R branch transitions in a CN ground electronic state. Therefore, the 355 nm beam was employed to directly excite the CN transitions with good efficiency. The CN measurements were performed in premixed CH 4 -N 2 O flames with varying equivalence ratios. A detailed characterization of the high-speed CN PLIF imaging system is presented via its ability to capture statistical and dynamical information in these premixed flames. Single-shot CN PLIF images obtained over a HMX pellet undergoing self-supported deflagration are presented as an example of the imaging system being applied towards characterizing the flame structure of energetic materials.

Investigation on navigation patterns of inertial/celestial integrated systems

NASA Astrophysics Data System (ADS)

Luo, Dacheng; Liu, Yan; Liu, Zhiguo; Jiao, Wei; Wang, Qiuyan

2014-11-01

It is known that Strapdown Inertial Navigation System (SINS), Global Navigation Satellite System (GNSS) and Celestial Navigation System (CNS) can complement each other's advantages. The SINS/CNS integrated system, which has the characteristics of strong autonomy, high accuracy and good anti-jamming, is widely used in military and civilian applications. Similar to SINS/GNSS integrated system, the SINS/CNS integrated system can also be divided into three kinds according to the difference of integrating depth, i.e., loosely coupled pattern, tightly coupled pattern and deeply coupled pattern. In this paper, the principle and characteristics of each pattern of SINS/CNS system are analyzed. Based on the comparison of these patterns, a novel deeply coupled SINS/CNS integrated navigation scheme is proposed. The innovation of this scheme is that a new star pattern matching method aided by SINS information is put forward. Thus the complementary features of these two subsystems are reflected.

Single virus and nanoparticle size spectrometry by whispering-gallery-mode microcavities

NASA Astrophysics Data System (ADS)

Zhu, Jiangang; Kaya Özdemir, Şahin; He, Lina; Chen, Da-Ren; Yang, Lan

2011-08-01

Detecting and characterizing single nanoparticles and airborne viruses are of paramount importance for disease control and diagnosis, for environmental monitoring, and for understanding size dependent properties of nanoparticles for developing innovative products. Although single particle and virus detection have been demonstrated in various platforms, single-shot size measurement of each detected particle has remained a significant challenge. Here, we present a nanoparticle size spectrometry scheme for label-free, real-time and continuous detection and sizing of single Influenza A virions, polystyrene and gold nanoparticles using split whispering-gallery-modes (WGMs) in an ultra-high-Q resonator. We show that the size of each particle and virion can be measured as they continuously bind to the resonator one-by-one, eliminating the need for ensemble measurements, stochastic analysis or imaging techniques employed in previous works. Moreover, we show that our scheme has the ability to identify the components of particle mixtures.

Polynomial elimination theory and non-linear stability analysis for the Euler equations

NASA Technical Reports Server (NTRS)

Kennon, S. R.; Dulikravich, G. S.; Jespersen, D. C.

1986-01-01

Numerical methods are presented that exploit the polynomial properties of discretizations of the Euler equations. It is noted that most finite difference or finite volume discretizations of the steady-state Euler equations produce a polynomial system of equations to be solved. These equations are solved using classical polynomial elimination theory, with some innovative modifications. This paper also presents some preliminary results of a new non-linear stability analysis technique. This technique is applicable to determining the stability of polynomial iterative schemes. Results are presented for applying the elimination technique to a one-dimensional test case. For this test case, the exact solution is computed in three iterations. The non-linear stability analysis is applied to determine the optimal time step for solving Burgers' equation using the MacCormack scheme. The estimated optimal time step is very close to the time step that arises from a linear stability analysis.

Educational Innovation as a Process of Coalition-Building: A Study of Organizational Decision-Making. Volume I: Analysis and Conclusions.

ERIC Educational Resources Information Center

Lambright, W. Henry; And Others

Local school districts must strengthen their innovative capacity in order to respond effectively to the problems facing them. Success depends on both an organization's technical capacity to match problems with appropriate solutions and its political capacity to move an innovation through the process from adoption to incorporation. Research shows…

The Evolution of the MasAgro Hubs: Responsiveness and Serendipity as Drivers of Agricultural Innovation in a Dynamic and Heterogeneous Context

ERIC Educational Resources Information Center

Camacho-Villa, Tania Carolina; Almekinders, Conny; Hellin, Jon; Martinez-Cruz, Tania Eulalia; Rendon-Medel, Roberto; Guevara-Hernández, Francisco; Beuchelt, Tina D.; Govaerts, Bram

2016-01-01

Purpose: Little is known about effective ways to operationalize agricultural innovation processes. We use the MasAgro program in Mexico (which aims to increase maize and wheat productivity, profitability and sustainability), and the experiences of middle level "hub managers", to understand how innovation processes occur in heterogeneous…

Developing and evaluating innovative items for the NCLEX: Part 2, item characteristics and cognitive processing.

PubMed

Wendt, Anne; Harmes, J Christine

2009-01-01

This article is a continuation of the research on the development and evaluation of innovative item formats for the NCLEX examinations that was published in the March/April 2009 edition of Nurse Educator. The authors discuss the innovative item templates and evaluate the statistical characteristics and level of cognitive processing required to answer the examination items.

Curriculum reform and evolution: Innovative content and processes at one US medical school.

PubMed

Fischel, Janet E; Olvet, Doreen M; Iuli, Richard J; Lu, Wei-Hsin; Chandran, Latha

2018-03-11

Curriculum reform in medical schools continues to be an ever-present and challenging activity in medical education. This paper describes one school's experiences with specific curricular innovations that were developed or adapted and targeted to meet a clear set of curricular goals during the curriculum reform process. Those goals included: (a) promoting active learning and learner engagement; (b) establishing early professional identity; and (c) developing physician competencies in an integrated and contextual manner while allowing for individualized learning experiences for the millennial student. Six specific innovations championed by the school are described in detail. These included Themes in Medical Education, Translational Pillars, Stony Brook Teaching Families, Transition Courses, Educational Continuous Quality Improvement Processes, and our Career Advising Program. Development of the ideas and design of the innovations were done by faculty and student teams. We discuss successes and ongoing challenges with these innovations which are currently in the fourth year of implementation. Our curriculum reform has emphasized the iterative process of curriculum building. Based on our experience, we discuss general and practical guidelines for curriculum innovation in its three phases: setting the stage, implementation, and monitoring for the achievement of intended goals.

Development of a program for tele-rehabilitation of COPD patients across sectors: co-innovation in a network

PubMed Central

Dinesen, Birthe; Seeman, Janne; Gustafsson, Jeppe

2011-01-01

Introduction The aim of the Telekat project is to prevent re-admissions of patients with chronic obstructive pulmonary disease (COPD) by developing a preventive program of tele-rehabilitation across sectors for COPD patients. The development of the program is based on a co-innovation process between COPD patients, relatives, healthcare professionals and representatives from private firms and universities. This paper discusses the obstacles that arise in the co-innovation process of developing an integrated technique for tele-rehabilitation of COPD patients. Theory Network and innovation theory. Methods The case study was applied. A triangulation of data collection techniques was used: documents, observations (123 hours), qualitative interviews (n=32) and action research. Findings Obstacles were identified in the network context; these obstacles included the mindset of the healthcare professionals, inter-professionals relations, views of technology as a tool and competing visions for the goals of tele-rehabilitation. Conclusion We have identified obstacles that emerge in the co-innovation process when developing a programme for tele-rehabilitation of COPD patients in an inter-organizational context. Action research has been carried out and can have helped to facilitate the co-innovation process. PMID:21637709

Technology adoption and implementation in organisations: comparative case studies of 12 English NHS Trusts

PubMed Central

Ahmad, Raheelah; Holmes, Alison

2012-01-01

Objectives To understand organisational technology adoption (initiation, adoption decision, implementation) by looking at the different types of innovation knowledge used during this process. Design Qualitative, multisite, comparative case study design. Setting One primary care and 11 acute care organisations (trusts) across all health regions in England in the context of infection prevention and control. Participants and data analysis 121 semistructured individual and group interviews with 109 informants, involving clinical and non-clinical staff from all organisational levels and various professional groups. Documentary evidence and field notes were also used. 38 technology adoption processes were analysed using an integrated approach combining inductive and deductive reasoning. Main findings Those involved in the process variably accessed three types of innovation knowledge: ‘awareness’ (information that an innovation exists), ‘principles’ (information about an innovation's functioning principles) and ‘how-to’ (information required to use an innovation properly at individual and organisational levels). Centralised (national, government-led) and local sources were used to obtain this knowledge. Localised professional networks were preferred sources for all three types of knowledge. Professional backgrounds influenced an asymmetric attention to different types of innovation knowledge. When less attention was given to ‘how-to’ compared with ‘principles’ knowledge at the early stages of the process, this contributed to 12 cases of incomplete implementation or discontinuance after initial adoption. Conclusions Potential adopters and change agents often overlooked or undervalued ‘how-to’ knowledge. Balancing ‘principles’ and ‘how-to’ knowledge early in the innovation process enhanced successful technology adoption and implementation by considering efficacy as well as strategic, structural and cultural fit with the organisation's context. This learning is critical given the policy emphasis for health organisations to be innovation-ready. PMID:22492183

A novel all-optical label processing for OPS networks based on multiple OOC sequences from multiple-groups OOC

NASA Astrophysics Data System (ADS)

Qiu, Kun; Zhang, Chongfu; Ling, Yun; Wang, Yibo

2007-11-01

This paper proposes an all-optical label processing scheme using multiple optical orthogonal codes sequences (MOOCS) for optical packet switching (OPS) (MOOCS-OPS) networks, for the first time to the best of our knowledge. In this scheme, the multiple optical orthogonal codes (MOOC) from multiple-groups optical orthogonal codes (MGOOC) are permuted and combined to obtain the MOOCS for the optical labels, which are used to effectively enlarge the capacity of available optical codes for optical labels. The optical label processing (OLP) schemes are reviewed and analyzed, the principles of MOOCS-based optical labels for OPS networks are given, and analyzed, then the MOOCS-OPS topology and the key realization units of the MOOCS-based optical label packets are studied in detail, respectively. The performances of this novel all-optical label processing technology are analyzed, the corresponding simulation is performed. These analysis and results show that the proposed scheme can overcome the lack of available optical orthogonal codes (OOC)-based optical labels due to the limited number of single OOC for optical label with the short code length, and indicate that the MOOCS-OPS scheme is feasible.

Variance reduction for Fokker–Planck based particle Monte Carlo schemes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorji, M. Hossein, E-mail: gorjih@ifd.mavt.ethz.ch; Andric, Nemanja; Jenny, Patrick

Recently, Fokker–Planck based particle Monte Carlo schemes have been proposed and evaluated for simulations of rarefied gas flows [1–3]. In this paper, the variance reduction for particle Monte Carlo simulations based on the Fokker–Planck model is considered. First, deviational based schemes were derived and reviewed, and it is shown that these deviational methods are not appropriate for practical Fokker–Planck based rarefied gas flow simulations. This is due to the fact that the deviational schemes considered in this study lead either to instabilities in the case of two-weight methods or to large statistical errors if the direct sampling method is applied.more » Motivated by this conclusion, we developed a novel scheme based on correlated stochastic processes. The main idea here is to synthesize an additional stochastic process with a known solution, which is simultaneously solved together with the main one. By correlating the two processes, the statistical errors can dramatically be reduced; especially for low Mach numbers. To assess the methods, homogeneous relaxation, planar Couette and lid-driven cavity flows were considered. For these test cases, it could be demonstrated that variance reduction based on parallel processes is very robust and effective.« less

Development of a new British Geologcial Survey(BGS) Map Series: Seabed Geomorphology

NASA Astrophysics Data System (ADS)

Dove, Dayton

2015-04-01

BGS scientists are developing a new offshore map series, Seabed Geomorphology (1:50k), to join the existing 1:250k 'Sea Bed Sediments', 'Quaternary Geology', and 'Solid Geology' map series. The increasing availability of extensive high-resolution swath bathymetry data (e.g. MCA's Civil Hydrography Programme) provides an unprecedented opportunity to characterize the processes which formed, and actively govern the physical seabed environment. Mapping seabed geomorphology is an effective means to describe individual, or groups of features whose form and other physical attributes (e.g. symmetry) may be used to distinguish feature origin. Swath bathymetry also provides added and renewed value to other data types (e.g. grab samples, legacy seismic data). In such cases the geomorphic evidence may be expanded to make inferences on the evolution of seabed features as well as their association with the underlying geology and other environmental variables/events over multiple timescales. Classifying seabed geomorphology is not particularly innovative or groundbreaking. Terrestrial geomorphology is of course a well established field of science, and within the marine environment for example, mapping submarine glacial landforms has probably become the most reliable method to reconstruct the extent and dynamics of past ice-sheets. What is novel here, and we believe useful/necessary for a survey organization, is to standardise the geomorphological classification scheme such that it is applicable to multiple and diverse environments. The classification scheme should be sufficiently detailed and interpretive to be informative, but not so detailed that we over-interpret or become mired in disputed feature designations or definitions. We plan to present the maps at 1:50k scale with the intention that these maps will be 'enabling' resources for research, educational, commercial, and policy purposes, much like the existing 1:250k map series. We welcome feedback on the structure and content of the proposed classification scheme, as well as the anticipated value to respective user communities.

Application of Intel Many Integrated Core (MIC) accelerators to the Pleim-Xiu land surface scheme

NASA Astrophysics Data System (ADS)

Huang, Melin; Huang, Bormin; Huang, Allen H.

2015-10-01

The land-surface model (LSM) is one physics process in the weather research and forecast (WRF) model. The LSM includes atmospheric information from the surface layer scheme, radiative forcing from the radiation scheme, and precipitation forcing from the microphysics and convective schemes, together with internal information on the land's state variables and land-surface properties. The LSM is to provide heat and moisture fluxes over land points and sea-ice points. The Pleim-Xiu (PX) scheme is one LSM. The PX LSM features three pathways for moisture fluxes: evapotranspiration, soil evaporation, and evaporation from wet canopies. To accelerate the computation process of this scheme, we employ Intel Xeon Phi Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.3x and 11.7x as compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670.

Health Care Coverage Decision Making in Low- and Middle-Income Countries: Experiences from 25 Coverage Schemes.

PubMed

Gutierrez, Hialy; Shewade, Ashwini; Dai, Minghan; Mendoza-Arana, Pedro; Gómez-Dantés, Octavio; Jain, Nishant; Khonelidze, Irma; Nabyonga-Orem, Juliet; Saleh, Karima; Teerawattananon, Yot; Nishtar, Sania; Hornberger, John

2015-08-01

Lessons learned by countries that have successfully implemented coverage schemes for health services may be valuable for other countries, especially low- and middle-income countries (LMICs), which likewise are seeking to provide/expand coverage. The research team surveyed experts in population health management from LMICs for information on characteristics of health care coverage schemes and factors that influenced decision-making processes. The level of coverage provided by the different schemes varied. Nearly all the health care coverage schemes involved various representatives and stakeholders in their decision-making processes. Maternal and child health, cardiovascular diseases, cancer, and HIV were among the highest priorities guiding coverage development decisions. Evidence used to inform coverage decisions included medical literature, regional and global epidemiology, and coverage policies of other coverage schemes. Funding was the most commonly reported reason for restricting coverage. This exploratory study provides an overview of health care coverage schemes from participating LMICs and contributes to the scarce evidence base on coverage decision making. Sharing knowledge and experiences among LMICs can support efforts to establish systems for accessible, affordable, and equitable health care.

Optimization of the scheme for natural ecology planning of urban rivers based on ANP (analytic network process) model.

PubMed

Zhang, Yichuan; Wang, Jiangping

2015-07-01

Rivers serve as a highly valued component in ecosystem and urban infrastructures. River planning should follow basic principles of maintaining or reconstructing the natural landscape and ecological functions of rivers. Optimization of planning scheme is a prerequisite for successful construction of urban rivers. Therefore, relevant studies on optimization of scheme for natural ecology planning of rivers is crucial. In the present study, four planning schemes for Zhaodingpal River in Xinxiang City, Henan Province were included as the objects for optimization. Fourteen factors that influenced the natural ecology planning of urban rivers were selected from five aspects so as to establish the ANP model. The data processing was done using Super Decisions software. The results showed that important degree of scheme 3 was highest. A scientific, reasonable and accurate evaluation of schemes could be made by ANP method on natural ecology planning of urban rivers. This method could be used to provide references for sustainable development and construction of urban rivers. ANP method is also suitable for optimization of schemes for urban green space planning and design.

A genetic fuzzy analytical hierarchy process based projection pursuit method for selecting schemes of water transportation projects

NASA Astrophysics Data System (ADS)

Jin, Juliang; Li, Lei; Wang, Wensheng; Zhang, Ming

2006-10-01

The optimal selection of schemes of water transportation projects is a process of choosing a relatively optimal scheme from a number of schemes of water transportation programming and management projects, which is of importance in both theory and practice in water resource systems engineering. In order to achieve consistency and eliminate the dimensions of fuzzy qualitative and fuzzy quantitative evaluation indexes, to determine the weights of the indexes objectively, and to increase the differences among the comprehensive evaluation index values of water transportation project schemes, a projection pursuit method, named FPRM-PP for short, was developed in this work for selecting the optimal water transportation project scheme based on the fuzzy preference relation matrix. The research results show that FPRM-PP is intuitive and practical, the correction range of the fuzzy preference relation matrix A it produces is relatively small, and the result obtained is both stable and accurate; therefore FPRM-PP can be widely used in the optimal selection of different multi-factor decision-making schemes.

The Canadian Precipitation Analysis (CaPA): Evaluation of the statistical interpolation scheme

NASA Astrophysics Data System (ADS)

Evans, Andrea; Rasmussen, Peter; Fortin, Vincent

2013-04-01

CaPA (Canadian Precipitation Analysis) is a data assimilation system which employs statistical interpolation to combine observed precipitation with gridded precipitation fields produced by Environment Canada's Global Environmental Multiscale (GEM) climate model into a final gridded precipitation analysis. Precipitation is important in many fields and applications, including agricultural water management projects, flood control programs, and hydroelectric power generation planning. Precipitation is a key input to hydrological models, and there is a desire to have access to the best available information about precipitation in time and space. The principal goal of CaPA is to produce this type of information. In order to perform the necessary statistical interpolation, CaPA requires the estimation of a semi-variogram. This semi-variogram is used to describe the spatial correlations between precipitation innovations, defined as the observed precipitation amounts minus the GEM forecasted amounts predicted at the observation locations. Currently, CaPA uses a single isotropic variogram across the entire analysis domain. The present project investigates the implications of this choice by first conducting a basic variographic analysis of precipitation innovation data across the Canadian prairies, with specific interest in identifying and quantifying potential anisotropy within the domain. This focus is further expanded by identifying the effect of storm type on the variogram. The ultimate goal of the variographic analysis is to develop improved semi-variograms for CaPA that better capture the spatial complexities of precipitation over the Canadian prairies. CaPA presently applies a Box-Cox data transformation to both the observations and the GEM data, prior to the calculation of the innovations. The data transformation is necessary to satisfy the normal distribution assumption, but introduces a significant bias. The second part of the investigation aims at devising a bias correction scheme based on a moving-window averaging technique. For both the variogram and bias correction components of this investigation, a series of trial runs are conducted to evaluate the impact of these changes on the resulting CaPA precipitation analyses.

Innovative Environments In Health Care: Where And How New Approaches To Care Are Succeeding.

PubMed

Bates, David W; Sheikh, Aziz; Asch, David A

2017-03-01

Organizations seeking to create innovative environments in health care need to pay attention to a number of factors. These include making available sufficient resources, notably money and physical space, but also coordination and consultation regarding intellectual property and licensing; enabling access to engineers, software developers, and behavioral scientists; making providers and patients available to innovators; having a sufficiently long-term view; and insulating the innovation group from operational demands. If there is a single essential key to success, it is making innovation a strategic priority. Academic health systems are enormous generators of innovation in the form of generalizable research in biomedical sciences. Typically, much of that innovation is externally supported, and little is directed to improving care processes internally. In industries other than health care, organizations invest their own funds in research and development to promote innovation, and this investment is seen as a metric for a firm's commitment to its future. Increased investment in care-process innovation is long overdue. Project HOPE—The People-to-People Health Foundation, Inc.

New, Improved Bulk-microphysical Schemes for Studying Precipitation Processes in WRF. Part 1; Comparisons with Other Schemes

NASA Technical Reports Server (NTRS)

Tao, W.-K.; Shi, J.; Chen, S. S> ; Lang, S.; Hong, S.-Y.; Thompson, G.; Peters-Lidard, C.; Hou, A.; Braun, S.;

Turbulence mitigation scheme based on multiple-user detection in an orbital-angular-momentum multiplexed system

NASA Astrophysics Data System (ADS)

Zou, Li; Wang, Le; Zhao, Sheng-Mei; Chen, Han-Wu

2016-11-01

Atmospheric turbulence (AT) induced crosstalk can significantly impair the performance of a free-space optical (FSO) communication link using orbital angular momentum (OAM) multiplexing. In this paper, we propose a multiple-user detection (MUD) turbulence mitigation scheme in an OAM-multiplexed FSO communication link. First, we present a MUD equivalent communication model for an OAM-multiplexed FSO communication link under AT. In the equivalent model, each input bit stream represents one user’s information. The deformed OAM spatial modes caused by AT, instead of the pure OAM spatial modes, are used as information carriers, and the overlapping between the deformed OAM spatial modes are computed as the correlation coefficients between the users. Then, we present a turbulence mitigation scheme based on MUD idea to enhance AT tolerance of the OAM-multiplexed FSO communication link. In the proposed scheme, the crosstalk caused by AT is used as a useful component to deduce users’ information. The numerical results show that the performance of the OAM-multiplexed communication link has greatly improved by the proposed scheme. When the turbulence strength is 1 × 10-15 m-2/3, the transmission distance is 1000 m and the channel signal-to-noise ratio (SNR) is 26 dB, the bit-error-rate (BER) performance of four spatial multiplexed OAM modes lm = +1,+2,+3,+4 are all close to 10-5, and there is a 2-3 fold increase in the BER performance in comparison with those results without the proposed scheme. In addition, the proposed scheme is more effective for an OAM-multiplexed FSO communication link with a larger OAM mode topological charge interval. The proposed scheme is a promising direction for compensating the interference caused by AT in the OAM-multiplexed FSO communication link. Project supported by the National Natural Science Foundation of China (Grant Nos. 61271238 and 61475075), the Open Research Fund of Key Lab of Broadband Wireless Communication and Sensor Network Technology, Ministry of Education, China (Grant No. NYKL2015011), the Postgraduate Innovation Research Plan of Jiangsu Province, China (Grant No. CXZZ13_0489), and the University Natural Science Foundation of Jiangsu Province, China (Grant No. 16KJB510037).

Innovative single-shot diagnostics for electrons accelerated through laser-plasma interaction at FLAME

NASA Astrophysics Data System (ADS)

Bisesto, F. G.; Anania, M. P.; Chiadroni, E.; Cianchi, A.; Costa, G.; Curcio, A.; Ferrario, M.; Galletti, M.; Pompili, R.; Schleifer, E.; Zigler, A.

2017-05-01

Plasma wakefield acceleration is the most promising acceleration technique known nowadays, able to provide very high accelerating fields (> 100 GV/m), enabling acceleration of electrons to GeV energy in few centimeters. Here we present all the plasma related activities currently underway at SPARC LAB exploiting the high power laser FLAME. In particular, we will give an overview of the single shot diagnostics employed: Electro Optic Sampling (EOS) for temporal measurement and optical transition radiation (OTR) for an innovative one shot emittance measurements. In detail, the EOS technique has been employed to measure for the first time the longitudinal profile of electric field of fast electrons escaping from a solid target, driving the ions and protons acceleration, and to study the impact of using different target shapes. Moreover, a novel scheme for one shot emittance measurements based on OTR, developed and tested at SPARC LAB LINAC, will be shown.

National Institutes of Health phase I, Small Business Innovation Research applications: fiscal year 1983 results.

PubMed

Vener, K J

1985-08-01

A review of the 356 disapproved Small Business Innovation Research (SBIR) proposals submitted to the National Institutes of Health (NIH) for fiscal year 1983 funding was undertaken to identify the most common shortcomings of those disapproved applications. The shortcomings were divided into four general classes by using the scheme developed by other authors when describing the reasons for the disapproval of regular NIH research applications. Comparison of the reasons for disapproval of SBIR applications with regular applications suggests comparable difficulties in the areas of the problem and the approach. There is some indication, however, that the SBIR proposals may have been weaker in the category of the principal investigator (PI). In general, it is the responsibility of the PI to demonstrate that the work is timely and can be performed with available technology and expertise, and that the guidelines for the NIH SBIR program have been satisfied.

A compact eyetracked optical see-through head-mounted display

NASA Astrophysics Data System (ADS)

Hua, Hong; Gao, Chunyu

2012-03-01

An eye-tracked head-mounted display (ET-HMD) system is able to display virtual images as a classical HMD does, while additionally tracking the gaze direction of the user. There is ample evidence that a fully-integrated ETHMD system offers multi-fold benefits, not only to fundamental scientific research but also to emerging applications of such technology. For instance eyetracking capability in HMDs adds a very valuable tool and objective metric for scientists to quantitatively assess user interaction with 3D environments and investigate the effectiveness of various 3D visualization technologies for various specific tasks including training, education, and augmented cognition tasks. In this paper, we present an innovative optical approach to the design of an optical see-through ET-HMD system based on freeform optical technology and an innovative optical scheme that uniquely combines the display optics with the eye imaging optics. A preliminary design of the described ET-HMD system will be presented.

How Can Innovative Learning Environments Promote the Diffusion of Innovation?

ERIC Educational Resources Information Center

Osborne, Mark

2016-01-01

Schools implementing innovative learning environments (ILEs) face many challenges, including the need to discard previously cherished practices and behaviours, adjust mindsets, and invent successful new ways of operating. Leaders can support these processes by implementing structures that: i) support ongoing, distributed, participatory innovation;…

76 FR 76388 - National Medal of Technology and Innovation Nomination Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-07

... Medal of Technology and Innovation is the highest honor for technological achievement bestowed by the... commercialization of technology products, processes and concepts, technological innovation, and development of the Nation's technological manpower. The purpose of the National Medal of Technology and Innovation is to...

Three Perspectives on Innovation--the Technological, the Political, and the Cultural. Draft.

ERIC Educational Resources Information Center

House, Ernest R.

Awareness of the three analytical perspectives on educational innovation leads to better understanding of educational change processes and better innovation strategies and policies. The three perspectives--technological, political, and cultural--are "screens" of facts, values, and presuppositions through which analysts view innovation.…

Work(er)-Driven Innovation

ERIC Educational Resources Information Center

Smith, Raymond

2017-01-01

Purpose: The focus on innovation as a foundational element of enhanced organisational performance has led to the promoting and valuing of greater levels of employee participation in innovation processes. An emergent concept of employee-driven innovation could be argued to have hindered understandings of the creative and transformative nature of…

Is Transferring an Educational Innovation Actually a Process of Transformation?

ERIC Educational Resources Information Center

Varpio, Lara; Bell, Robert; Hollingworth, Gary; Jalali, Alireza; Haidet, Paul; Levine, Ruth; Regehr, Glenn

2012-01-01

Recent debates question the extent to which adopting an educational innovation requires compromise between the innovation's original design and the adoption site's context. Through compromises, the innovation's fundamental principles may be transferred, transformed, or abandoned. This paper analyzes such compromises during the piloting of…

Key Knowledge Providers as Sources of Business Innovation

ERIC Educational Resources Information Center

Fernandez-Esquinas, Manuel; Merchan-Hernandez, Carmen; Ramos-Vielba, Irene; Martinez-Fernandez, Cristina

2010-01-01

Studies of innovation are giving increasing attention to the relationships that businesses maintain with different participants in the innovation process. It is generally assumed that interaction with other businesses, universities and government organizations can generate knowledge that will improve the ability to innovate. However, there is…

Pot, politics and the press--reflections on cannabis law reform in Western Australia.

PubMed

Lenton, Simon

2004-06-01

Windows of opportunity for changing drug laws open infrequently and they often close without legislative change being affected. In this paper the author, who has been intimately involved in the process, describes how evidence-based recommendations to 'decriminalize' cannabis have recently been progressed through public debate and the political process to become law in Western Australia (WA). The Cannabis Control Bill 2003 passed the WA Parliament on 23 September. The Bill, the legislative backing behind the Cannabis Infringement Notice (CIN) Scheme, came into effect on 22 March 2004. This made WA the fourth Australian jurisdiction, after South Australia, the Australian Capital Territory and the Northern Territory, to adopt a prohibition with civil penalties scheme for minor cannabis offences. This paper describes some of the background to the scheme, the process by which it has become law, the main provisions of the scheme and its evaluation. It includes reflections on the role of politics and the press in the process. The process of implementation and evaluation are outlined by the author, foreshadowing an ongoing opportunity to understand the impact of the change in legislation.

Applying social innovation theory to examine how community co-designed health services develop: using a case study approach and mixed methods.

PubMed

Farmer, Jane; Carlisle, Karen; Dickson-Swift, Virginia; Teasdale, Simon; Kenny, Amanda; Taylor, Judy; Croker, Felicity; Marini, Karen; Gussy, Mark

2018-01-31

Citizen participation in health service co-production is increasingly enacted. A reason for engaging community members is to co-design services that are locally-appropriate and harness local assets. To date, much literature examines processes of involving participants, with little consideration of innovative services are designed, how innovations emerge, develop and whether they sustain or diffuse. This paper addresses this gap by examining co-designed initiatives through the lens of social innovation - a conceptualisation more attuned to analysing grassroots innovation than common health services research approaches considering top-down, technical innovations. This paper considers whether social innovation is a useful frame for examining co-designed services. Eighty-eight volunteer community-based participants from six rural Australian communities were engaged using the same, tested co-design framework for a 12-month design and then 12-month implementation phase, in 24 workshops (2014-16). Mixed, qualitative data were collected and used to formulate five case studies of community co-designed innovations. A social innovation theory, derived from literature, was applied as an analytical frame to examine co-design cases at 3 stages: innovation growth, development and sustainability/diffusion. Social innovation theory was found relevant in examining and understanding what occurred at each stage of innovation development. Innovations themselves were all adaptations of existing ideas. They emerged due to local participants combining knowledge from local context, own experiences and exemplars. External facilitation brought resources together. The project provided a protective niche in which pilot innovations developed, but they needed support from managers and/or policymakers to be implemented; and to be compatible with existing health system practices. For innovations to move to sustainability/diffusion required political relationships. Challenging existing practice without these was problematical. Social innovation provides a useful lens to understand the grassroots innovation process implied in community participation in service co-design. It helps to show problems in co-design processes and highlights the need for strong partnerships and advocacy beyond the immediate community for new ideas to thrive. Regional commissioning organisations are intended to diffuse useful, co-designed service innovations. Efforts are required to develop an innovation system to realise the potential of community involvement in co-design.

Innovation in the forest products industry: an analysis of companies in Alaska and Oregon.

Treesearch

Abra Hovgaard; Eric Hansen; Joseph Roos

2005-01-01

Because there is a lack of innovation research in the forest products industry and innovative activities in the industry are not well documented, this study attempted to fill that void. The objectives of this study were to understand the process and definition of innovation in the forest products industry, identify the constraints on innovative activities, identify...

European Innovation Policy Concepts and the Governance of Innovation: Slovenia and the Struggle for Organizational Readiness at the National Level

ERIC Educational Resources Information Center

Gebhardt, Christiane; Stanovnik, Peter

2016-01-01

This paper examines the interdependency of European Policy and governance of innovation. The authors elaborate on the policy implementation context of Slovenia, a small and less advanced European member state in a transition process. The literature on innovation policy, governance and existing innovation concepts aiming to accelerate economic…

Service innovation management practices in the telecommunications industry: what does cross country analysis reveal?

PubMed

Rahman, Syed Abidur; Taghizadeh, Seyedeh Khadijeh; Ramayah, T; Ahmad, Noor Hazlina

2015-01-01

Service innovation management practice is currently being widely scrutinized mainly in the developed countries, where it has been initiated. The current study attempts to propose a framework and empirically validate and explain the service innovation practices for successful performance in the telecommunications industry of two developing countries, Malaysia and Bangladesh. The research framework proposes relationships among organisational culture, operating core (innovation process, cross-functional organisation, and implementation of tools/technology), competition-informed pricing, and performance. A total of 176 usable data from both countries are analysed for the purpose of the research. The findings show that organisational culture tends to be more influential on innovation process and cross-functional organisation in Malaysian telecommunication industry. In contrast, implementation of tools/technology plays a more instrumental role in competition-informed pricing practices in Bangladesh. This study revealed few differences in the innovation management practices between two developing countries. The findings have strategic implications for the service sectors in both the developing countries regarding implementation of innovative enterprises, especially in Bangladesh where innovation is the basis for survival. Testing the innovation management practices in the developing countries perhaps contains uniqueness in the field of innovation management.

The association of hospital governance with innovation in Taiwan.

PubMed

Yang, Chen-Wei; Yan, Yu-Hua; Fang, Shih-Chieh; Inamdar, Syeda Noorein; Lin, Hsien-Cheng

2018-01-01

Hospitals in Taiwan are facing major changes and innovation is increasingly becoming a critical factor for remaining competitive. One determinant that can have a significant impact on innovation is hospital governance. However, there is limited prior research on the relationship between hospital governance and innovation. The purpose of this study is to propose a conceptual framework to hypothesize the relationship between governance mechanisms and innovation and to empirically test the hypotheses in hospital organizations. We examine the relationship between governance mechanisms and innovation using data on 102 hospitals in Taiwan from the Taiwan Joint Commission on Hospital Accreditation and Quality Improvement. We model governance mechanisms using board structure, information transparency and strategic decision-making processes. For our modeling and data analysis we use measurement and structural models. We find that in hospital governance, information transparency and strategic decision making did impact innovation. However, governance structure did not. To facilitate innovation, hospital boards can increase information transparency and improve the decision-making process when considering strategic investments in innovative initiatives. To remain competitive, hospital boards need to develop and monitor indices that measure hospital innovation to ensure ongoing progress. Copyright © 2017 John Wiley & Sons, Ltd.

Toward Sustainable Anticipatory Governance: Analyzing and Assessing Nanotechnology Innovation Processes

NASA Astrophysics Data System (ADS)

Foley, Rider Williams

Cities around the globe struggle with socio-economic disparities, resource inefficiency, environmental contamination, and quality-of-life challenges. Technological innovation, as one prominent approach to problem solving, promises to address these challenges; yet, introducing new technologies, such as nanotechnology, into society and cities has often resulted in negative consequences. Recent research has conceptually linked anticipatory governance and sustainability science: to understand the role of technology in complex problems our societies face; to anticipate negative consequences of technological innovation; and to promote long-term oriented and responsible governance of technologies. This dissertation advances this link conceptually and empirically, focusing on nanotechnology and urban sustainability challenges. The guiding question for this dissertation research is: How can nanotechnology be innovated and governed in responsible ways and with sustainable outcomes? The dissertation: analyzes the nanotechnology innovation process from an actor- and activities-oriented perspective (Chapter 2); assesses this innovation process from a comprehensive perspective on sustainable governance (Chapter 3); constructs a small set of future scenarios to consider future implications of different nanotechnology governance models (Chapter 4); and appraises the amenability of sustainability problems to nanotechnological interventions (Chapter 5). The four studies are based on data collected through literature review, document analysis, participant observation, interviews, workshops, and walking audits, as part of process analysis, scenario construction, and technology assessment. Research was conducted in collaboration with representatives from industry, government agencies, and civic organizations. The empirical parts of the four studies focus on Metropolitan Phoenix. Findings suggest that: predefined mandates and economic goals dominate the nanotechnology innovation process; normative responsibilities identified by risk governance, sustainability-oriented governance, and anticipatory governance are infrequently considered in the nanotechnology innovation process; different governance models will have major impacts on the role and effects of nanotechnology in cities in the future; and nanotechnologies, currently, do not effectively address the root causes of urban sustainability challenges and require complementary solution approaches. This dissertation contributes to the concepts of anticipatory governance and sustainability science on how to constructively guide nanotechnological innovation in order to harvest its positive potential and safeguard against negative consequences.

Intelligent Power Swing Detection Scheme to Prevent False Relay Tripping Using S-Transform

NASA Astrophysics Data System (ADS)

Mohamad, Nor Z.; Abidin, Ahmad F.; Musirin, Ismail

2014-06-01

Distance relay design is equipped with out-of-step tripping scheme to ensure correct distance relay operation during power swing. The out-of-step condition is a consequence result from unstable power swing. It requires proper detection of power swing to initiate a tripping signal followed by separation of unstable part from the entire power system. The distinguishing process of unstable swing from stable swing poses a challenging task. This paper presents an intelligent approach to detect power swing based on S-Transform signal processing tool. The proposed scheme is based on the use of S-Transform feature of active power at the distance relay measurement point. It is demonstrated that the proposed scheme is able to detect and discriminate the unstable swing from stable swing occurring in the system. To ascertain validity of the proposed scheme, simulations were carried out with the IEEE 39 bus system and its performance has been compared with the wavelet transform-based power swing detection scheme.

Subtraction with hadronic initial states at NLO: an NNLO-compatible scheme

NASA Astrophysics Data System (ADS)

Somogyi, Gábor

2009-05-01

We present an NNLO-compatible subtraction scheme for computing QCD jet cross sections of hadron-initiated processes at NLO accuracy. The scheme is constructed specifically with those complications in mind, that emerge when extending the subtraction algorithm to next-to-next-to-leading order. It is therefore possible to embed the present scheme in a full NNLO computation without any modifications.

The Community Innovation Process: A Conceptualization and Empirical Analysis.

ERIC Educational Resources Information Center

Agnew, John A.; And Others

1978-01-01

Previous research into the community innovation process has tended to emphasize either intercommunity communication or local socioeconomic and political factors. This article incorporates both sets of factors in an analysis of urban renewal, public housing, automated data processing by local municipalities, and public water fluoridation.…

Stereotactic body radiotherapy for lung cancer: how much does it really cost?

PubMed

Lievens, Yolande; Obyn, Caroline; Mertens, Anne-Sophie; Van Halewyck, Dries; Hulstaert, Frank

2015-03-01

Despite the lack of randomized evidence, stereotactic body radiotherapy (SBRT) is being accepted as superior to conventional radiotherapy for patients with T1-2N0 non-small-cell lung cancer in the periphery of the lung and unfit or unwilling to undergo surgery. To introduce SBRT in a system of coverage with evidence development, a correct financing had to be determined. A time-driven activity-based costing model for radiotherapy was developed. Resource cost calculation of all radiotherapy treatments, standard and innovative, was conducted in 10 Belgian radiotherapy centers in the second half of 2012. The average cost of lung SBRT across the 10 centers (6221&OV0556;) is in the range of the average costs of standard fractionated 3D-conformal radiotherapy (5919&OV0556;) and intensity-modulated radiotherapy (7379&OV0556;) for lung cancer. Hypofractionated 3D-conformal radiotherapy and intensity-modulated radiotherapy schemes are less costly (3993&OV0556; respectively 4730&OV0556;). The SBRT cost increases with the number of fractions and is highly dependent of personnel and equipment use. SBRT cost varies more by centre than conventional radiotherapy cost, reflecting different technologies, stages in the learning curve and a lack of clear guidance in this field. Time-driven activity-based costing of radiotherapy is feasible in a multicentre setup, resulting in real-life resource costs that can form the basis for correct reimbursement schemes, supporting an early yet controlled introduction of innovative radiotherapy techniques in clinical practice.

Power corrections in the N -jettiness subtraction scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boughezal, Radja; Liu, Xiaohui; Petriello, Frank

We discuss the leading-logarithmic power corrections in the N-jettiness subtraction scheme for higher-order perturbative QCD calculations. We compute the next-to-leading order power corrections for an arbitrary N-jet process, and we explicitly calculate the power correction through next-to-next-to-leading order for color-singlet production for bothmore » $$q\\bar{q}$$ and gg initiated processes. Our results are compact and simple to implement numerically. Including the leading power correction in the N-jettiness subtraction scheme substantially improves its numerical efficiency. Finally, we discuss what features of our techniques extend to processes containing final-state jets.« less

Power corrections in the N -jettiness subtraction scheme

DOE PAGES

Boughezal, Radja; Liu, Xiaohui; Petriello, Frank

2017-03-30

We discuss the leading-logarithmic power corrections in the N-jettiness subtraction scheme for higher-order perturbative QCD calculations. We compute the next-to-leading order power corrections for an arbitrary N-jet process, and we explicitly calculate the power correction through next-to-next-to-leading order for color-singlet production for bothmore » $$q\\bar{q}$$ and gg initiated processes. Our results are compact and simple to implement numerically. Including the leading power correction in the N-jettiness subtraction scheme substantially improves its numerical efficiency. Finally, we discuss what features of our techniques extend to processes containing final-state jets.« less

Using the Donabedian framework to examine the quality and safety of nursing service innovation.

PubMed

Gardner, Glenn; Gardner, Anne; O'Connell, Jane

2014-01-01

To evaluate the safety and quality of nurse practitioner service using the audit framework of Structure, Process and Outcome. Health service and workforce reform are on the agenda of governments and other service providers seeking to contain healthcare costs whilst providing safe and effective health care to communities. The nurse practitioner service is one health workforce innovation that has been adopted globally to improve timely access to clinical care, but there is scant literature reporting evaluation of the quality of this service innovation. A mixed-methods design within the Donabedian evaluation framework was used. The Donabedian framework was used to evaluate the Structure, Process and Outcome of nurse practitioner service. A range of data collection approaches was used, including stakeholder survey (n = 36), in-depth interviews (11 patients and 13 nurse practitioners) and health records data on service processes. The study identified that adequate and detailed preparation of Structure and Process is essential for the successful implementation of a service innovation. The multidisciplinary team was accepting of the addition of nurse practitioner service, and nurse practitioner clinical care was shown to be effective, satisfactory and safe from the perspective of the clinician stakeholders and patients. This study demonstrated that the Donabedian framework of Structure, Process and Outcome evaluation is a valuable and validated approach to examine the safety and quality of a service innovation. Furthermore, in this study, specific Structure elements were shown to influence the quality of service processes further validating the framework and the interdependence of the Structure, Process and Outcome components. Understanding the Structure and Process requirements for establishing nursing service innovation lays the foundation for safe, effective and patient-centred clinical care. © 2013 John Wiley & Sons Ltd.

Innovation in mental health services: what are the key components of success?

PubMed

Brooks, Helen; Pilgrim, David; Rogers, Anne

2011-10-26

Service development innovation in health technology and practice is viewed as a pressing need within the field of mental health yet is relatively poorly understood. Macro-level theories have been criticised for their limited explanatory power and they may not be appropriate for understanding local and fine-grained uncertainties of services and barriers to the sustainability of change. This study aimed to identify contextual influences inhibiting or promoting the acceptance and integration of innovations in mental health services in both National Health Service (NHS) and community settings. A comparative study using qualitative and case study data collection methods, including semi-structured interviews with key stakeholders and follow-up telephone interviews over a one-year period. The analysis was informed by learning organisation theory. Drawn from 11 mental health innovation projects within community, voluntary and NHS settings, 65 participants were recruited including service users, commissioners, health and non-health professionals, managers, and caregivers. The methods deployed in this evaluation focused on process-outcome links within and between the 11 projects. Key barriers to innovation included resistance from corporate departments and middle management, complexity of the innovation, and the availability and access to resources on a prospective basis within the host organisation. The results informed the construction of a proposed model of innovation implementation within mental health services. The main components of which are context, process, and outcomes. The study produced a model of conducive and impeding factors drawn from the composite picture of 11 innovative mental health projects, and this is discussed in light of relevant literature. The model provides a rich agenda to consider for services wanting to innovate or adopt innovations from elsewhere. The evaluation suggested the importance of studying innovation with a focus on context, process, and outcomes.

Understanding healthcare innovation systems: the Stockholm region case.

PubMed

Larisch, Lisa-Marie; Amer-Wåhlin, Isis; Hidefjäll, Patrik

2016-11-21

Purpose There is an increasing interest in understanding how innovation processes can address current challenges in healthcare. The purpose of this paper is to analyze the wider socio-economic context and conditions for such innovation processes in the Stockholm region, using the functional dynamics approach to innovation systems (ISs). Design/methodology/approach The analysis is based on triangulation using data from 16 in-depth interviews, two workshops, and additional documents. Using the functional dynamics approach, critical structural and functional components of the healthcare IS were analyzed. Findings The analysis revealed several mechanisms blocking innovation processes such as fragmentation, lack of clear leadership, as well as insufficient involvement of patients and healthcare professionals. Furthermore, innovation is expected to occur linearly as a result of research. Restrictive rules for collaboration with industry, reimbursement, and procurement mechanisms limit entrepreneurial experimentation, commercialization, and spread of innovations. Research limitations/implications In this study, the authors analyzed how certain functions of the functional dynamics approach to ISs related to each other. The authors grouped knowledge creation, resource mobilization, and legitimacy as they jointly constitute conditions for needs articulation and entrepreneurial experimentation. The economic effects of entrepreneurial experimentation and needs articulation are mainly determined by the stage of market formation and existence of positive externalities. Social implications Stronger user involvement; a joint innovation strategy for healthcare, academia, and industry; and institutional reform are necessary to remove blocking mechanisms that today prevent innovation from occurring. Originality/value This study is the first to provide an analysis of the system of innovation in healthcare using a functional dynamics approach, which has evolved as a tool for public policy making. A better understanding of ISs in general, and in healthcare in particular, may provide the basis for designing and evaluating innovation policy.

Innovation in mental health services: what are the key components of success?

PubMed Central

2011-01-01

Background Service development innovation in health technology and practice is viewed as a pressing need within the field of mental health yet is relatively poorly understood. Macro-level theories have been criticised for their limited explanatory power and they may not be appropriate for understanding local and fine-grained uncertainties of services and barriers to the sustainability of change. This study aimed to identify contextual influences inhibiting or promoting the acceptance and integration of innovations in mental health services in both National Health Service (NHS) and community settings. Methods A comparative study using qualitative and case study data collection methods, including semi-structured interviews with key stakeholders and follow-up telephone interviews over a one-year period. The analysis was informed by learning organisation theory. Drawn from 11 mental health innovation projects within community, voluntary and NHS settings, 65 participants were recruited including service users, commissioners, health and non-health professionals, managers, and caregivers. The methods deployed in this evaluation focused on process-outcome links within and between the 11 projects. Results Key barriers to innovation included resistance from corporate departments and middle management, complexity of the innovation, and the availability and access to resources on a prospective basis within the host organisation. The results informed the construction of a proposed model of innovation implementation within mental health services. The main components of which are context, process, and outcomes. Conclusions The study produced a model of conducive and impeding factors drawn from the composite picture of 11 innovative mental health projects, and this is discussed in light of relevant literature. The model provides a rich agenda to consider for services wanting to innovate or adopt innovations from elsewhere. The evaluation suggested the importance of studying innovation with a focus on context, process, and outcomes. PMID:22029930

Medical innovation then and now: perspectives of innovators responsible for transformative drugs.

PubMed

Xu, Shuai; Kesselheim, Aaron S

2014-01-01

Effective medical innovation is a common goal of policymakers, physicians, researchers, and patients both in the private and public sectors. With the recent slowdown in approval of new transformative prescription drugs, many have looked back to the "golden years" of the 1980s and 1990s when numerous breakthrough products emerged. We conducted a qualitative study of innovators (n=127) directly involved in creation of groundbreaking drugs during that era to determine what made their work successful and how the process of conducting medical innovation has changed over the past 3 decades. Transcripts were analyzed using standard coding techniques and the constant comparative method of qualitative data analysis to identify the positive features of and challenges posed by the past and present therapeutic innovation environments (70 of the 127 interviewees explicitly addressed these issues). Interviewees emphasized the continued central role played by individuals and the institutions they were a part of in driving innovation. In addition, respondents discussed the importance of collaboration between individuals and institutions to share resources and expertise. Strong underlying basic science was also cited to be a major contributing factor to the success of an innovation. The climate for modern-day medical innovation involves a greater emphasis on patenting in academia, difficulty negotiating the technology transfer process, and funding constraints. Regulatory demands or reimbursement concerns were not commonly cited as factors that influenced transformative innovation. This study suggests that generating future transformative innovation will require a simplification of the current technology transfer process, continued commitment to basic science research, and policy changes that promote meaningful collaboration between individuals from disparate institutions. © 2014 American Society of Law, Medicine & Ethics, Inc.

Tension as an Enabling Characteristic of Innovating in Schools

ERIC Educational Resources Information Center

Perillo, Suzanne

2007-01-01

Purpose: The purpose of this paper is to argue that school innovation is a complex process requiring a detailed accounting of the relational activity characterising everyday innovating activity. It is further proposed that complex accounts of innovation practice that describe social factors only are insufficient. Design/methodology/approach: Using…

Bridging the Innovation Gap--An Interview with Robert Johnston.

ERIC Educational Resources Information Center

Larson, Cynthia M.

1993-01-01

This interview with a founding partner of a consulting firm specializing in product and process innovation discusses the need for American businesses to rethink their one-shot approach to innovation and implement instead a systems approach to supporting and managing innovation. A strong collaborative effort that reaches throughout the organization…

An Examination of the Navy’s Future Naval Capability Technology Transition Process

DTIC Science & Technology

2004-12-01

managing innovation , innovation is a lot of art and a little science. b. Innovation Skills The President of the small manufacturing company...34 managing innovation ", the breakthroughs do not come from managed, tightly structured programs. The development of those breakthroughs into truly useful

Evaluating Eco-Innovation of OECD Countries with Data Envelopment Analysis

ERIC Educational Resources Information Center

Mavi, Reza Kiani; Standing, Craig

2016-01-01

Government regulations require businesses to improve their processes and products/services in a green and sustainable manner. For being environmentally friendly, businesses should invest more on eco-innovation practices. Firms eco-innovate to promote eco-efficiency and sustainability. This paper evaluates the eco-innovation performance of…

ARM - Midlatitude Continental Convective Clouds

DOE Data Explorer

Jensen, Mike; Bartholomew, Mary Jane; Genio, Anthony Del; Giangrande, Scott; Kollias, Pavlos

2012-01-19

Convective processes play a critical role in the Earth's energy balance through the redistribution of heat and moisture in the atmosphere and their link to the hydrological cycle. Accurate representation of convective processes in numerical models is vital towards improving current and future simulations of Earths climate system. Despite improvements in computing power, current operational weather and global climate models are unable to resolve the natural temporal and spatial scales important to convective processes and therefore must turn to parameterization schemes to represent these processes. In turn, parameterization schemes in cloud-resolving models need to be evaluated for their generality and application to a variety of atmospheric conditions. Data from field campaigns with appropriate forcing descriptors have been traditionally used by modelers for evaluating and improving parameterization schemes.

ARM - Midlatitude Continental Convective Clouds (comstock-hvps)

DOE Data Explorer

Jensen, Mike; Comstock, Jennifer; Genio, Anthony Del; Giangrande, Scott; Kollias, Pavlos

2012-01-06

Convective processes play a critical role in the Earth's energy balance through the redistribution of heat and moisture in the atmosphere and their link to the hydrological cycle. Accurate representation of convective processes in numerical models is vital towards improving current and future simulations of Earths climate system. Despite improvements in computing power, current operational weather and global climate models are unable to resolve the natural temporal and spatial scales important to convective processes and therefore must turn to parameterization schemes to represent these processes. In turn, parameterization schemes in cloud-resolving models need to be evaluated for their generality and application to a variety of atmospheric conditions. Data from field campaigns with appropriate forcing descriptors have been traditionally used by modelers for evaluating and improving parameterization schemes.

Innovativeness as an emergent property: a new alignment of comparative and experimental research on animal innovation

PubMed Central

Griffin, Andrea S.

2016-01-01

Innovation and creativity are key defining features of human societies. As we face the global challenges of the twenty-first century, they are also facets upon which we must become increasingly reliant. But what makes Homo sapiens so innovative and where does our high innovation propensity come from? Comparative research on innovativeness in non-human animals allows us to peer back through evolutionary time and investigate the ecological factors that drove the evolution of innovativeness, whereas experimental research identifies and manipulates underpinning creative processes. In commenting on the present theme issue, I highlight the controversies that have typified this research field and show how a paradigmatic shift in our thinking about innovativeness will contribute to resolving these tensions. In the past decade, innovativeness has been considered by many as a trait, a direct product of cognition, and a direct target of selection. The evidence I review here suggests that innovativeness will be hereon viewed as one component, or even an emergent property of a larger array of traits, which have evolved to deal with environmental variation. I illustrate how research should capitalize on taxonomic diversity to unravel the full range of psychological processes that underpin innovativeness in non-human animals. PMID:26926287

A New Proxy Electronic Voting Scheme Achieved by Six-Particle Entangled States

NASA Astrophysics Data System (ADS)

Cao, Hai-Jing; Ding, Li-Yuan; Jiang, Xiu-Li; Li, Peng-Fei

2018-03-01

In this paper, we use quantum proxy signature to construct a new secret electronic voting scheme. In our scheme, six particles entangled states function as quantum channels. The voter Alice, the Vote Management Center Bob, the scrutineer Charlie only perform two particles measurements on the Bell bases to realize the electronic voting process. So the scheme reduces the technical difficulty and increases operation efficiency. We use quantum key distribution and one-time pad to guarantee its unconditional security. The significant advantage of our scheme is that transmitted information capacity is twice as much as the capacity of other schemes.

SME 2.0: Roadmap towards Web 2.0-Based Open Innovation in SME-Networks - A Case Study Based Research Framework

NASA Astrophysics Data System (ADS)

Lindermann, Nadine; Valcárcel, Sylvia; Schaarschmidt, Mario; von Kortzfleisch, Harald

Small- and medium sized enterprises (SMEs) are of high social and economic importance since they represent 99% of European enterprises. With regard to their restricted resources, SMEs are facing a limited capacity for innovation to compete with new challenges in a complex and dynamic competitive environment. Given this context, SMEs need to increasingly cooperate to generate innovations on an extended resource base. Our research project focuses on the aspect of open innovation in SME-networks enabled by Web 2.0 applications and referring to innovative solutions of non-competitive daily life problems. Examples are industrial safety, work-life balance issues or pollution control. The project raises the question whether the use of Web 2.0 applications can foster the exchange of creativity and innovative ideas within a network of SMEs and hence catalyze new forms of innovation processes among its participants. Using Web 2.0 applications within SMEs implies consequently breaking down innovation processes to employees’ level and thus systematically opening up a heterogeneous and broader knowledge base to idea generation. In this paper we address first steps on a roadmap towards Web 2.0-based open innovation processes within SME-networks. It presents a general framework for interaction activities leading to open innovation and recommends a regional marketplace as a viable, trust-building driver for further collaborative activities. These findings are based on field research within a specific SME-network in Rhineland-Palatinate Germany, the “WirtschaftsForum Neuwied e.V.”, which consists of roughly 100 heterogeneous SMEs employing about 8,000 workers.

Implementation of the NANoREG Safe-by-Design approach for different nanomaterial applications

NASA Astrophysics Data System (ADS)

Micheletti, C.; Roman, M.; Tedesco, E.; Olivato, I.; Benetti, F.

2017-06-01

The Safe-by-Design (SbD) concept is already in use in different industrial sectors as an integral part of the innovation process management. However, the adopted approach is often limited to design solutions aiming at hazard reduction. Safety is not always considered during the innovation process, mainly due to the lack of knowledge (e.g. in small and medium companies, SMEs) and the lack of dialogue between actors along the innovation chain. The net result is that safety is considered only at the end of the innovation process at the market authorization phase, with potential loss of time and money. This is especially valid for manufactured nanomaterials (MNM) for which the regulatory context is not completely developed, and the safety knowledge is not readily available. In order to contribute to a sustainable innovation process in the nanotechnology field by maximising both benefits and safety, the NANoREG project developed a Safe Innovation approach, based on two elements: the Safe-by-Design approach which aims at including risk assessment into all innovation stages; and the Regulatory Preparedness, focused on the dialogue with stakeholders along the innovation chain. In this work we present some examples about the implementation in our Laboratory of this approach for different MNM applications, covering different steps of the innovation chain. The case studies include: the feasibility study of a medical device including substances, for topical application; the testing of two potential nanotech solutions for the consolidation of cultural heritage artifacts; the testing of coatings already on the market for other uses, which was tested as food contact materials (FCM) to evaluate the conformity to food applications. These three examples represent a good opportunity to show the importance of NANoREG SbD and Safe Innovation Approach in general, for developing new nanotechnology-based products, also highlighting the crucial role of EU ProSafe project in promoting this concept to industries and interested stakeholders.

The Impact of Parameterized Convection on Climatological Precipitation in Atmospheric Global Climate Models

NASA Astrophysics Data System (ADS)

Maher, Penelope; Vallis, Geoffrey K.; Sherwood, Steven C.; Webb, Mark J.; Sansom, Philip G.

2018-04-01

Convective parameterizations are widely believed to be essential for realistic simulations of the atmosphere. However, their deficiencies also result in model biases. The role of convection schemes in modern atmospheric models is examined using Selected Process On/Off Klima Intercomparison Experiment simulations without parameterized convection and forced with observed sea surface temperatures. Convection schemes are not required for reasonable climatological precipitation. However, they are essential for reasonable daily precipitation and constraining extreme daily precipitation that otherwise develops. Systematic effects on lapse rate and humidity are likewise modest compared with the intermodel spread. Without parameterized convection Kelvin waves are more realistic. An unexpectedly large moist Southern Hemisphere storm track bias is identified. This storm track bias persists without convection schemes, as does the double Intertropical Convergence Zone and excessive ocean precipitation biases. This suggests that model biases originate from processes other than convection or that convection schemes are missing key processes.

The Process of Accepting Technology Innovation for Rural Teachers

ERIC Educational Resources Information Center

Cerovski, Jeremy

2016-01-01

In order for educational leaders to facilitate effectively the integration of technology, an understanding of the process rural teachers experience with technology integration is critical. The goal of the qualitative study was to discover and understand rural teachers' process for accepting technology innovation in order to improve the…

FROM CONCEPT TO EQUIVALENCY: GETTING YOUR INNOVATIVE SLUDGE DISINFECTION PROCESS CLASSIFIED AS A OR B IS NOW LESS OF A MYSTERY

EPA Science Inventory

The Pathogen Equivalency Committee has updated the criteria it uses to make recommendations of equivalency on innovative or alternative sludge pathogen reduction processes. To assist new applicants through the equivalency recommendation process the pathogen equivalency committee ...

Addressing the medicinal chemistry bottleneck: a lean approach to centralized purification.

PubMed

Weller, Harold N; Nirschl, David S; Paulson, James L; Hoffman, Steven L; Bullock, William H

2012-09-10

The use of standardized lean manufacturing principles to improve drug discovery productivity is often thought to be at odds with fostering innovation. This manuscript describes how selective implementation of a lean optimized process, in this case centralized purification for medicinal chemistry, can improve operational productivity and increase scientist time available for innovation. A description of the centralized purification process is provided along with both operational and impact (productivity) metrics, which indicate lower cost, higher output, and presumably more free time for innovation as a result of the process changes described.

Double-moment cloud microphysics scheme for the deep convection parameterization in the GFDL AM3

NASA Astrophysics Data System (ADS)

Belochitski, A.; Donner, L.

2014-12-01

A double-moment cloud microphysical scheme originally developed by Morrision and Gettelman (2008) for the stratiform clouds and later adopted for the deep convection by Song and Zhang (2011) has been implemented in to the Geophysical Fluid Dynamics Laboratory's atmospheric general circulation model AM3. The scheme treats cloud drop, cloud ice, rain, and snow number concentrations and mixing ratios as diagnostic variables and incorporates processes of autoconversion, self-collection, collection between hydrometeor species, sedimentation, ice nucleation, drop activation, homogeneous and heterogeneous freezing, and the Bergeron-Findeisen process. Such detailed representation of microphysical processes makes the scheme suitable for studying the interactions between aerosols and convection, as well as aerosols' indirect effects on clouds and their roles in climate change. The scheme is first tested in the single column version of the GFDL AM3 using forcing data obtained at the U.S. Department of Energy Atmospheric Radiation Measurment project's Southern Great Planes site. Scheme's impact on SCM simulations is discussed. As the next step, runs of the full atmospheric GCM incorporating the new parameterization are compared to the unmodified version of GFDL AM3. Global climatological fields and their variability are contrasted with those of the original version of the GCM. Impact on cloud radiative forcing and climate sensitivity is investigated.

Double-moment Cloud Microphysics Scheme for the Deep Convection Parameterization in the GFDL AM3

NASA Astrophysics Data System (ADS)

Belochitski, A.; Donner, L.

2013-12-01

A double-moment cloud microphysical scheme originally developed by Morrision and Gettelman (2008) for the stratiform clouds and later adopted for the deep convection by Song and Zhang (2011) is being implemented in to the deep convection parameterization of Geophysical Fluid Dynamics Laboratory's atmospheric general circulation model AM3. The scheme treats cloud drop, cloud ice, rain, and snow number concentrations and mixing ratios as diagnostic variables and incorporates processes of autoconversion, self-collection, collection between hydrometeor species, sedimentation, ice nucleation, drop activation, homogeneous and heterogeneous freezing, and the Bergeron-Findeisen process. Detailed representation of microphysical processes makes the scheme suitable for studying the interactions between aerosols and convection, as well as aerosols' indirect effects on clouds and the roles of these effects in climate change. The scheme is implemented into the single column version of the GFDL AM3 and evaluated using large scale forcing data obtained at the U.S. Department of Energy Atmospheric Radiation Measurment project's Southern Great Planes and Tropical West Pacific sites. Sensitivity of the scheme to formulations for autoconversion of cloud water and its accretion by rain, self-collection of rain and self-collection of snow, as well as the formulation for heterogenous ice nucleation is investigated. In the future, tests with the full atmospheric GCM will be conducted.

Dynamically protected cat-qubits: a new paradigm for universal quantum computation

NASA Astrophysics Data System (ADS)

Mirrahimi, Mazyar; Leghtas, Zaki; Albert, Victor V.; Touzard, Steven; Schoelkopf, Robert J.; Jiang, Liang; Devoret, Michel H.

2014-04-01

We present a new hardware-efficient paradigm for universal quantum computation which is based on encoding, protecting and manipulating quantum information in a quantum harmonic oscillator. This proposal exploits multi-photon driven dissipative processes to encode quantum information in logical bases composed of Schrödinger cat states. More precisely, we consider two schemes. In a first scheme, a two-photon driven dissipative process is used to stabilize a logical qubit basis of two-component Schrödinger cat states. While such a scheme ensures a protection of the logical qubit against the photon dephasing errors, the prominent error channel of single-photon loss induces bit-flip type errors that cannot be corrected. Therefore, we consider a second scheme based on a four-photon driven dissipative process which leads to the choice of four-component Schrödinger cat states as the logical qubit. Such a logical qubit can be protected against single-photon loss by continuous photon number parity measurements. Next, applying some specific Hamiltonians, we provide a set of universal quantum gates on the encoded qubits of each of the two schemes. In particular, we illustrate how these operations can be rendered fault-tolerant with respect to various decoherence channels of participating quantum systems. Finally, we also propose experimental schemes based on quantum superconducting circuits and inspired by methods used in Josephson parametric amplification, which should allow one to achieve these driven dissipative processes along with the Hamiltonians ensuring the universal operations in an efficient manner.

MeMoVolc report on classification and dynamics of volcanic explosive eruptions

NASA Astrophysics Data System (ADS)

Bonadonna, C.; Cioni, R.; Costa, A.; Druitt, T.; Phillips, J.; Pioli, L.; Andronico, D.; Harris, A.; Scollo, S.; Bachmann, O.; Bagheri, G.; Biass, S.; Brogi, F.; Cashman, K.; Dominguez, L.; Dürig, T.; Galland, O.; Giordano, G.; Gudmundsson, M.; Hort, M.; Höskuldsson, A.; Houghton, B.; Komorowski, J. C.; Küppers, U.; Lacanna, G.; Le Pennec, J. L.; Macedonio, G.; Manga, M.; Manzella, I.; Vitturi, M. de'Michieli; Neri, A.; Pistolesi, M.; Polacci, M.; Ripepe, M.; Rossi, E.; Scheu, B.; Sulpizio, R.; Tripoli, B.; Valade, S.; Valentine, G.; Vidal, C.; Wallenstein, N.

2016-11-01

Classifications of volcanic eruptions were first introduced in the early twentieth century mostly based on qualitative observations of eruptive activity, and over time, they have gradually been developed to incorporate more quantitative descriptions of the eruptive products from both deposits and observations of active volcanoes. Progress in physical volcanology, and increased capability in monitoring, measuring and modelling of explosive eruptions, has highlighted shortcomings in the way we classify eruptions and triggered a debate around the need for eruption classification and the advantages and disadvantages of existing classification schemes. Here, we (i) review and assess existing classification schemes, focussing on subaerial eruptions; (ii) summarize the fundamental processes that drive and parameters that characterize explosive volcanism; (iii) identify and prioritize the main research that will improve the understanding, characterization and classification of volcanic eruptions and (iv) provide a roadmap for producing a rational and comprehensive classification scheme. In particular, classification schemes need to be objective-driven and simple enough to permit scientific exchange and promote transfer of knowledge beyond the scientific community. Schemes should be comprehensive and encompass a variety of products, eruptive styles and processes, including for example, lava flows, pyroclastic density currents, gas emissions and cinder cone or caldera formation. Open questions, processes and parameters that need to be addressed and better characterized in order to develop more comprehensive classification schemes and to advance our understanding of volcanic eruptions include conduit processes and dynamics, abrupt transitions in eruption regime, unsteadiness, eruption energy and energy balance.

Significant and Basic Innovations in Urban Planning

NASA Astrophysics Data System (ADS)

Kolyasnikov, V. A.

2017-11-01

The article considers the development features of the innovative urban planning in the USSR and Russia in XVIII - XX centuries. Innovative urban planning is defined as an activity on innovations creation and their implementation to obtain a socio-economic, political, environmental or other effect. In the course of urban development history this activity represents a cyclic wave process in which there are phases of rise and fall. The study of cyclic waves in the development of innovative urban planning uses the concept of basic and epochal innovations selection. This concept was developed by scientists for the study of cyclic wave processes in economics. Its adaptation to the conditions of innovative urban planning development allows one to introduce the concept of “basic innovation” and “significant innovation” in the theory and practice of settlement formation and their systems as well as to identify opportunities to highlight these innovations in the history of Russian urban planning. From these positions, six innovation waves committed to the urban development over the past 300 years are being investigated. The observed basic innovations in the domestic urban area show that urban development is a vital area for ensuring the country’s geopolitical security. Basic innovations are translated in time and modernized under new conditions of urban planning development. In this regard, we can predict the development of four basic innovations in post-Soviet Russia.

Efficiency of innovative technology in construction industry

NASA Astrophysics Data System (ADS)

Stverkova, H.; Vaclavik, V.

2017-10-01

The need for sustainability increasingly influences the development of new technologies, business processes and working practices. Innovations are an important part of all business processes. The aim of innovation is, in particular, to reduce the burden on the environment. The current trend in the construction industry is diamond rope cutting. The aim of the paper is to evaluate the most advanced technology for cutting and removing concrete structures in terms of efficiency.

Understanding Whole Systems Change in Health Care: Insights into System Level Diffusion from Nursing Service Delivery Innovations--A Multiple Case Study

ERIC Educational Resources Information Center

Berta, Whitney; Virani, Tazim; Bajnok, Irmajean; Edwards, Nancy; Rowan, Margo

2014-01-01

Our study responds to calls for theory-driven approaches to studying innovation diffusion processes in health care. While most research on diffusion in health care is situated at the service delivery level, we study innovations and associated processes that have diffused to the system level, and refer to work on complex adaptive systems and whole…

Perceptions of an international interprofessional education experience: Findings from students based in Europe and North America.

PubMed

Macauley, Kelly; Skov, Hanne; Lehtonen, Krista; Shulman, Brian

2016-09-01

The globalisation of healthcare is changing the demands placed on health professionals. It requires different skills and thought processes across national borders. Thinking in an innovative manner may provide healthcare workers with some of the necessary tools to facilitate international change by increasing students' mental flexibility and ability to apply solutions in multiple contexts. We created the International Innovation Program for health profession education students to learn about and implement the innovation process. The programme provides students the opportunity to learn in interprofessional, international teams and apply didactic knowledge to community problems using the innovation process. The purpose of this article is to describe student perceptions across 4 years of programme implementation. Through analysis of closed-ended survey data, we found that students who participated in the programme reported improvements in collaboration and teamwork, project management, interprofessional teamwork, professional growth and development, thinking in an innovative manner, research and development skills, information seeking, and willingness to work on international projects. Analysis of the open-ended questions revealed five themes: language, teamwork and collaboration, cultural awareness, innovation process, and personal growth and self-improvement. The long-term, follow-up data indicate that these attributes can be transferred into a clinical context which have implications for improved collaboration and patient care.

The role of patient narratives in healthcare innovation: supporting translation and meaning making.

PubMed

Pedersen, Anne Reff

2016-01-01

The purpose of this paper is to investigate the process and impact of patient involvement in locally defined improvement projects in two hospital clinics. The paper particularly aims to examine how patient narratives, in the form of diaries and radio montage, help to create new insights into patient experience for healthcare professionals, and support professionals' enrolment and mobilisation in innovation projects. Two case studies were undertaken. These drew upon qualitative interviews with staff and participant observation during innovation workshops. Patient diaries and a recorded montage of patient voices were also collected. The findings illuminate translation processes in healthcare innovation and the emergence of meaning making process for staff through the active use of patient narratives. The paper highlights the critical role of meaning making as an enabler of patient-centred change processes in healthcare via: local clinic mangers defining problems and ideas; collecting and sharing patient narratives in innovation workshops; and healthcare professionals' interpretation of patient narratives supporting new insights into patient experience. This study demonstrates how healthcare professionals' meaning making can be supported by articulating, constructing, listening and interpreting patient narratives. The two cases demonstrate how patient narratives serve as reflective devices for healthcare professionals. This study presents a novel demonstration of the importance of patient narratives for translating healthcare innovation in a clinical practice setting.

A novel double loop control model design for chemical unstable processes.

PubMed

Cong, Er-Ding; Hu, Ming-Hui; Tu, Shan-Tung; Xuan, Fu-Zhen; Shao, Hui-He

2014-03-01

In this manuscript, based on Smith predictor control scheme for unstable process in industry, an improved double loop control model is proposed for chemical unstable processes. Inner loop is to stabilize integrating the unstable process and transform the original process to first-order plus pure dead-time dynamic stable process. Outer loop is to enhance the performance of set point response. Disturbance controller is designed to enhance the performance of disturbance response. The improved control system is simple with exact physical meaning. The characteristic equation is easy to realize stabilization. Three controllers are separately design in the improved scheme. It is easy to design each controller and good control performance for the respective closed-loop transfer function separately. The robust stability of the proposed control scheme is analyzed. Finally, case studies illustrate that the improved method can give better system performance than existing design methods. © 2013 ISA Published by ISA All rights reserved.

Experimental demonstration of selective quantum process tomography on an NMR quantum information processor

NASA Astrophysics Data System (ADS)

Gaikwad, Akshay; Rehal, Diksha; Singh, Amandeep; Arvind, Dorai, Kavita

2018-02-01

We present the NMR implementation of a scheme for selective and efficient quantum process tomography without ancilla. We generalize this scheme such that it can be implemented efficiently using only a set of measurements involving product operators. The method allows us to estimate any element of the quantum process matrix to a desired precision, provided a set of quantum states can be prepared efficiently. Our modified technique requires fewer experimental resources as compared to the standard implementation of selective and efficient quantum process tomography, as it exploits the special nature of NMR measurements to allow us to compute specific elements of the process matrix by a restrictive set of subsystem measurements. To demonstrate the efficacy of our scheme, we experimentally tomograph the processes corresponding to "no operation," a controlled-NOT (CNOT), and a controlled-Hadamard gate on a two-qubit NMR quantum information processor, with high fidelities.

Processes of Middle-Class Reproduction in a Graduate Employment Scheme

ERIC Educational Resources Information Center

Smart, Sarah; Hutchings, Merryn; Maylor, Uvanney; Mendick, Heather; Menter, Ian

2009-01-01

Teach First is an educational charity that places graduates to teach in "challenging" schools for two years. It is marketed as an opportunity to develop employability while "making a difference". In this paper, I examine the process of class reproduction occurring in this graduate employment scheme through examining the…

Democratizing Implementation and Innovation in Mental Health Care.

PubMed

Saxe, Glenn; Acri, Mary

2017-03-01

Improvements in the quality of mental health care in the United States depend on the successful implementation of evidence-based treatments (EBT's) in typical settings of care. Unfortunately, there is little evidence that EBT's are used in ways that would approximate their established fidelity standards in such settings. This article describes an approach to more successful implementation of EBT's via a collaborative process between intervention developers and intervention users (e.g. providers, administrators, consumers) called Lead-user Innovation. Lead-user Innovation democratizes the implementation process by integrating the expertise of lead-users in the delivery, adaptation, innovation and evaluation of EBT's.

An improved scheme for Flip-OFDM based on Hartley transform in short-range IM/DD systems.

PubMed

Zhou, Ji; Qiao, Yaojun; Cai, Zhuo; Ji, Yuefeng

2014-08-25

In this paper, an improved Flip-OFDM scheme is proposed for IM/DD optical systems, where the modulation/demodulation processing takes advantage of the fast Hartley transform (FHT) algorithm. We realize the improved scheme in one symbol period while conventional Flip-OFDM scheme based on fast Fourier transform (FFT) in two consecutive symbol periods. So the complexity of many operations in improved scheme is half of that in conventional scheme, such as CP operation, polarity inversion and symbol delay. Compared to FFT with complex input constellation, the complexity of FHT with real input constellation is halved. The transmission experiment over 50-km SSMF has been realized to verify the feasibility of improved scheme. In conclusion, the improved scheme has the same BER performance with conventional scheme, but great superiority on complexity.

Robotic Attention Processing And Its Application To Visual Guidance

NASA Astrophysics Data System (ADS)

Barth, Matthew; Inoue, Hirochika

1988-03-01

This paper describes a method of real-time visual attention processing for robots performing visual guidance. This robot attention processing is based on a novel vision processor, the multi-window vision system that was developed at the University of Tokyo. The multi-window vision system is unique in that it only processes visual information inside local area windows. These local area windows are quite flexible in their ability to move anywhere on the visual screen, change their size and shape, and alter their pixel sampling rate. By using these windows for specific attention tasks, it is possible to perform high speed attention processing. The primary attention skills of detecting motion, tracking an object, and interpreting an image are all performed at high speed on the multi-window vision system. A basic robotic attention scheme using the attention skills was developed. The attention skills involved detection and tracking of salient visual features. The tracking and motion information thus obtained was utilized in producing the response to the visual stimulus. The response of the attention scheme was quick enough to be applicable to the real-time vision processing tasks of playing a video 'pong' game, and later using an automobile driving simulator. By detecting the motion of a 'ball' on a video screen and then tracking the movement, the attention scheme was able to control a 'paddle' in order to keep the ball in play. The response was faster than that of a human's, allowing the attention scheme to play the video game at higher speeds. Further, in the application to the driving simulator, the attention scheme was able to control both direction and velocity of a simulated vehicle following a lead car. These two applications show the potential of local visual processing in its use for robotic attention processing.

Needs-Based Innovation in Interventional Radiology: The Biodesign Process.

PubMed

Steinberger, Jonathan D; Denend, Lyn; Azagury, Dan E; Brinton, Todd J; Makower, Josh; Yock, Paul G

2017-06-01

There are many possible mechanisms for innovation and bringing new technology into the marketplace. The Stanford Biodesign innovation process is based in a deep understanding of clinical unmet needs as the basis for focused ideation and development. By identifying and vetting a compelling unmet need, the aspiring innovator can "derisk" a project and maximize chances for successful development in an increasingly challenging regulatory and economic environment. As a specialty founded by tinkerers, with a history of disruptive innovation that has yielded countless new ways of delivering care with minimal invasiveness, lower morbidity, and lower cost, interventional radiologists are uniquely well positioned to identify unmet needs and develop novel solutions free of dogmatic convention. Copyright © 2017 Elsevier Inc. All rights reserved.

Additive Manufacturing of Nickel Superalloys: Opportunities for Innovation and Challenges Related to Qualification

NASA Astrophysics Data System (ADS)

Babu, S. S.; Raghavan, N.; Raplee, J.; Foster, S. J.; Frederick, C.; Haines, M.; Dinwiddie, R.; Kirka, M. K.; Plotkowski, A.; Lee, Y.; Dehoff, R. R.

2018-06-01

Innovative designs for turbines can be achieved by advances in nickel-based superalloys and manufacturing methods, including the adoption of additive manufacturing. In this regard, selective electron beam melting (SEBM) and selective laser melting (SLM) of nickel-based superalloys do provide distinct advantages. Furthermore, the direct energy deposition (DED) processes can be used for repair and reclamation of nickel alloy components. The current paper explores opportunities for innovation and qualification challenges with respect to deployment of AM as a disruptive manufacturing technology. In the first part of the paper, fundamental correlations of processing parameters to defect tendency and microstructure evolution will be explored using DED process. In the second part of the paper, opportunities for innovation in terms of site-specific control of microstructure during processing will be discussed. In the third part of the paper, challenges in qualification of AM parts for service will be discussed and potential methods to alleviate these issues through in situ process monitoring, and big data analytics are proposed.

Situational analysis and future directions of AYUSH: An assessment through 5-year plans of India

PubMed Central

Samal, Janmejaya

2015-01-01

AYUSH is an acronym for Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy. These are the six indigenous systems of medicine practiced in India. A department called Department of Indian System of medicine was created in March 1995 and renamed to AYUSH in November 2003 with a focus to provide increased attention for the development of these systems. Very recently, in 2014, a separate ministry was created under the union Government of India, which is headed by a minister of state. Planning regarding these systems of medicine was a part of 5-year planning process since 1951. Since then many developments have happened in this sector albeit the system was struggling with a great degree of uncertainty at the time of 1st5-year plan. A progressive path of development could be observed since the first to the 12th5-year plan. It was up to the 7thplan the growth was little sluggish and from 8thplan onward the growth took its pace and several innovative development processes could be observed thereafter. The system is gradually progressing ahead with a vision to be a globally accepted system, as envisaged in 11th5-year plan. Currently, AYUSH system is a part of mainstream health system implemented under National Rural Health Mission (NRHM). NRHM came into play in 2005 but implemented at ground level in 2006 and introduced the scheme of “Mainstreaming of AYUSH and revitalization of local health traditions” to strengthen public health services. This scheme is currently in operation in its second phase, since 1stApril 2012, with the 12th5-year plan. The scheme was primarily brought in to operation with three important objectives; choice of treatment system to the patients, strengthen facility functionally and strengthen the implementation of national health programmes, however, in some places it seems to be a forced medical pluralism owing to a top-down approach by the union government without considerable involvement of the concerned community. In this study, the 5-year planning documents have been reviewed, from the 1stplan to 12thplan, to enable reflection and throw some light into the future directions of AYUSH system. PMID:26649240

Situational analysis and future directions of AYUSH: An assessment through 5-year plans of India.

PubMed

Samal, Janmejaya

2015-01-01

AYUSH is an acronym for Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy. These are the six indigenous systems of medicine practiced in India. A department called Department of Indian System of medicine was created in March 1995 and renamed to AYUSH in November 2003 with a focus to provide increased attention for the development of these systems. Very recently, in 2014, a separate ministry was created under the union Government of India, which is headed by a minister of state. Planning regarding these systems of medicine was a part of 5-year planning process since 1951. Since then many developments have happened in this sector albeit the system was struggling with a great degree of uncertainty at the time of 1(st)5-year plan. A progressive path of development could be observed since the first to the 12(th)5-year plan. It was up to the 7(th)plan the growth was little sluggish and from 8(th)plan onward the growth took its pace and several innovative development processes could be observed thereafter. The system is gradually progressing ahead with a vision to be a globally accepted system, as envisaged in 11(th)5-year plan. Currently, AYUSH system is a part of mainstream health system implemented under National Rural Health Mission (NRHM). NRHM came into play in 2005 but implemented at ground level in 2006 and introduced the scheme of "Mainstreaming of AYUSH and revitalization of local health traditions" to strengthen public health services. This scheme is currently in operation in its second phase, since 1(st)April 2012, with the 12(th)5-year plan. The scheme was primarily brought in to operation with three important objectives; choice of treatment system to the patients, strengthen facility functionally and strengthen the implementation of national health programmes, however, in some places it seems to be a forced medical pluralism owing to a top-down approach by the union government without considerable involvement of the concerned community. In this study, the 5-year planning documents have been reviewed, from the 1(st)plan to 12(th)plan, to enable reflection and throw some light into the future directions of AYUSH system.

Communication of Innovations; A Cross-Cultural Approach.

ERIC Educational Resources Information Center

Rogers, Everett M.; Shoemaker, F. Floyd

How do innovations (defined as idea, products, and practices perceived as new by an individual) diffuse to members of a social system? The authors answer this and other questions about the character of innovators, the rate of adoption of ideas, and the decision-making process in 103 generalizations about diffusion of innovation. These propositions…

Insights on Using Developmental Evaluation for Innovating: A Case Study on the Cocreation of an Innovative Program

ERIC Educational Resources Information Center

Lam, Chi Yan; Shulha, Lyn M.

2015-01-01

This article contributes to research on evaluation by examining the capacity and contribution of developmental evaluation for innovating. This case study describes the "preformative development" of an educational program (from conceptualization to pilot implementation) and analyzes the processes of innovation within a developmental…

Cognition of Experts and Top Managers about the Changes in Innovation Space

ERIC Educational Resources Information Center

Bergman, Jukka-Pekka; Jantunen, Ari; Saksa, Juha-Matti; Hurmelinna-Laukkanen, Pia

2007-01-01

The innovation space has become more complex and knowledge-intensive. As a result, it is increasingly important to see innovations as knowledge that is embodied in learning and technical and organisational knowledge bases. However, in processes such as innovation development, individuals make sense of it and utilise existing knowledge differently…

Innovation Becoming Trajectories: Leveraging Lateral and Vertical Moves for Collaborative Diffusion of Twenty-First Century Learning Practices

ERIC Educational Resources Information Center

Hung, David; Toh, Yancy; Jamaludin, Azilawati; So, Hyo-Jeong

2017-01-01

This paper argues for innovation diffusion as a "becoming" process in the context of lateral and vertical moves. The context of these innovations involves technology-mediated innovations and their diffusion trajectories in the Singapore education system. Embedded in a centralized-decentralized dialectics, this paper traces particular…

Spatial and Social Networks in Organizational Innovation

ERIC Educational Resources Information Center

Wineman, Jean D.; Kabo, Felichism W.; Davis, Gerald F.

2009-01-01

Research on the enabling factors of innovation has focused on either the social component of organizations or on the spatial dimensions involved in the innovation process. But no one has examined the aggregate consequences of the link from spatial layout, to social networks, to innovation. This project enriches our understanding of how innovation…

Transforming the Roles of a Public Extension Agency to Strengthen Innovation: Lessons from the National Agricultural Extension Project in Bangladesh

ERIC Educational Resources Information Center

Chowdhury, Ataharul Huq; Odame, Helen Hambly; Leeuwis, Cees

2014-01-01

Purpose: The rapidly evolving nature of agricultural innovation processes in low-income countries requires agricultural extension agencies to transform the classical roles that previously supported linear information dissemination and adoption of innovation. In Bangladesh, strengthening agricultural innovation calls for facilitation of interactive…

Innovation and nested preferential growth in chess playing behavior

NASA Astrophysics Data System (ADS)

Perotti, J. I.; Jo, H.-H.; Schaigorodsky, A. L.; Billoni, O. V.

2013-11-01

Complexity develops via the incorporation of innovative properties. Chess is one of the most complex strategy games, where expert contenders exercise decision making by imitating old games or introducing innovations. In this work, we study innovation in chess by analyzing how different move sequences are played at the population level. It is found that the probability of exploring a new or innovative move decreases as a power law with the frequency of the preceding move sequence. Chess players also exploit already known move sequences according to their frequencies, following a preferential growth mechanism. Furthermore, innovation in chess exhibits Heaps' law suggesting similarities with the process of vocabulary growth. We propose a robust generative mechanism based on nested Yule-Simon preferential growth processes that reproduces the empirical observations. These results, supporting the self-similar nature of innovations in chess are important in the context of decision making in a competitive scenario, and extend the scope of relevant findings recently discovered regarding the emergence of Zipf's law in chess.

Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent.

PubMed

Nwaka, Solomon; Ochem, Alexander; Besson, Dominique; Ramirez, Bernadette; Fakorede, Foluke; Botros, Sanaa; Inyang, Uford; Mgone, Charles; Adae-Mensah, Ivan; Konde, Victor; Nyasse, Barthelemy; Okole, Blessed; Guantai, Anastasia; Loots, Glaudina; Atadja, Peter; Ndumbe, Peter; Sanou, Issa; Olesen, Ole; Ridley, Robert; Ilunga, Tshinko

2012-07-27

A pool of 38 pan-African Centres of Excellence (CoEs) in health innovation has been selected and recognized by the African Network for Drugs and Diagnostics Innovation (ANDI), through a competitive criteria based process. The process identified a number of opportunities and challenges for health R&D and innovation in the continent: i) it provides a direct evidence for the existence of innovation capability that can be leveraged to fill specific gaps in the continent; ii) it revealed a research and financing pattern that is largely fragmented and uncoordinated, and iii) it highlights the most frequent funders of health research in the continent. The CoEs are envisioned as an innovative network of public and private institutions with a critical mass of expertise and resources to support projects and a variety of activities for capacity building and scientific exchange, including hosting fellows, trainees, scientists on sabbaticals and exchange with other African and non-African institutions.

Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent

PubMed Central

2012-01-01

A pool of 38 pan-African Centres of Excellence (CoEs) in health innovation has been selected and recognized by the African Network for Drugs and Diagnostics Innovation (ANDI), through a competitive criteria based process. The process identified a number of opportunities and challenges for health R&D and innovation in the continent: i) it provides a direct evidence for the existence of innovation capability that can be leveraged to fill specific gaps in the continent; ii) it revealed a research and financing pattern that is largely fragmented and uncoordinated, and iii) it highlights the most frequent funders of health research in the continent. The CoEs are envisioned as an innovative network of public and private institutions with a critical mass of expertise and resources to support projects and a variety of activities for capacity building and scientific exchange, including hosting fellows, trainees, scientists on sabbaticals and exchange with other African and non-African institutions. PMID:22838941

Addressing the paradox of the team innovation process: A review and practical considerations.

PubMed

Thayer, Amanda L; Petruzzelli, Alexandra; McClurg, Caitlin E

2018-01-01

Facilitating team innovation is paramount to promoting progress in the science, technology, engineering, and math fields, as well as advancing national health, safety, prosperity, and welfare. However, innovation teams face a unique set of challenges due to the novelty and uncertainty that is core to the definition of innovation, as well as the paradoxical nature of idea generation and idea implementation processes. These and other challenges must be overcome for innovation teams to realize their full potential for producing change. The purpose of this review is, thus, to provide insight into the unique context that these teams function within and provide an integrative, evidence-based, and practically useful, organizing heuristic that focuses on the most important considerations for facilitating team innovation. Finally, we provide practical guidance for psychologists, organizations, practitioners, scientists, educators, policymakers, and others who employ teams to produce novel, innovative solutions to today's problems. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Innovation adoption: a review of theories and constructs.

PubMed

Wisdom, Jennifer P; Chor, Ka Ho Brian; Hoagwood, Kimberly E; Horwitz, Sarah M

2014-07-01

Many theoretical frameworks seek to describe the dynamic process of the implementation of innovations. Little is known, however, about factors related to decisions to adopt innovations and how the likelihood of adoption of innovations can be increased. Using a narrative synthesis approach, this paper compared constructs theorized to be related to adoption of innovations proposed in existing theoretical frameworks in order to identify characteristics likely to increase adoption of innovations. The overall goal was to identify elements across adoption frameworks that are potentially modifiable and, thus, might be employed to improve the adoption of evidence-based practices. The review identified 20 theoretical frameworks that could be grouped into two broad categories: theories that mainly address the adoption process (N = 10) and theories that address adoption within the context of implementation, diffusion, dissemination, and/or sustainability (N = 10). Constructs of leadership, operational size and structure, innovation fit with norms and values, and attitudes/motivation toward innovations each are mentioned in at least half of the theories, though there were no consistent definitions of measures for these constructs. A lack of precise definitions and measurement of constructs suggests further work is needed to increase our understanding of adoption of innovations.

Innovation and motivation in public health professionals.

PubMed

García-Goñi, Manuel; Maroto, Andrés; Rubalcaba, Luis

2007-12-01

Innovations in public health services promote increases in the health status of the population. Therefore, it is a major concern for health policy makers to understand the drivers of innovation processes. This paper focuses on the differences in behaviour of managers and front-line employees in the pro-innovative provision of public health services. We utilize a survey conducted on front-line employees and managers in public health institutions across six European countries. The survey covers topics related to satisfaction, or attitude towards innovation or their institution. We undertake principal components analysis and analysis of variance, and estimate a multinomial ordered probit model to analyse the existence of different behaviour in managers and front-line employees with respect to innovation. Perception of innovation is different for managers and front-line employees in public health institutions. While front-line employees' attitude depends mostly on the overall performance of the institution, managers feel more involved and motivated, and their behaviour depends more on individual and organisational innovative profiles. It becomes crucial to make both managers and front-line employees at public health institutions feel participative and motivated in order to maximise the benefits of technical or organisational innovative process in the health services provision.

Innovation Adoption: A Review of Theories and Constructs

PubMed Central

Chor, Ka Ho Brian; Hoagwood, Kimberly E.; Horwitz, Sarah M.

2013-01-01

Many theoretical frameworks seek to describe the dynamic process of the implementation of innovations. Little is known, however, about factors related to decisions to adopt innovations and how the likelihood of adoption of innovations can be increased. Using a narrative synthesis approach, this paper compared constructs theorized to be related to adoption of innovations proposed in existing theoretical frameworks in order to identify characteristics likely to increase adoption of innovations. The overall goal was to identify elements across adoption frameworks that are potentially modifiable and, thus, might be employed to improve the adoption of evidence-based practices. The review identified 20 theoretical frameworks that could be grouped into two broad categories: theories that mainly address the adoption process (N = 10) and theories that address adoption within the context of implementation, diffusion, dissemination, and/or sustainability (N = 10). Constructs of leadership, operational size and structure, innovation fit with norms and values, and attitudes/motivation toward innovations each are mentioned in at least half of the theories, though there were no consistent definitions of measures for these constructs. A lack of precise definitions and measurement of constructs suggests further work is needed to increase our understanding of adoption of innovations. PMID:23549911

Innovating the Standard Procurement System Through Electronic Commerce Technologies

DTIC Science & Technology

1999-12-01

commerce are emerging almost daily as businesses continue to realize the overwhelming ability of agent applications to reduce costs and improve ...processed using the SPS. The result may reduce cycle time, assist contracting professionals, improve the acquisition process, save money and aid...of innovation processes, and it offers enormous potential for helping organizations achieve major improvements in terms of process cost , time

Challenges in provider payment under the Ghana National Health Insurance Scheme: a case study of claims management in two districts.

PubMed

Sodzi-Tettey, S; Aikins, M; Awoonor-Williams, J K; Agyepong, I A

2012-12-01

In 2004, Ghana started implementing a National Health Insurance Scheme (NHIS) to remove cost as a barrier to quality healthcare. Providers were initially paid by fee - for - service. In May 2008, this changed to paying providers by a combination of Ghana - Diagnostic Related Groupings (G-DRGs) for services and fee - for - service for medicines through the claims process. The study evaluated the claims management processes for two District MHIS in the Upper East Region of Ghana. Retrospective review of secondary claims data (2008) and a prospective observation of claims management (2009) were undertaken. Qualitative and quantitative approaches were used for primary data collection using interview guides and checklists. The reimbursements rates and value of rejected claims were calculated and compared for both districts using the z test. The null hypothesis was that no differences existed in parameters measured. Claims processes in both districts were similar and predominantly manual. There were administrative capacity, technical, human resource and working environment challenges contributing to delays in claims submission by providers and vetting and payment by schemes. Both Schemes rejected less than 1% of all claims submitted. Significant differences were observed between the Total Reimbursement Rates (TRR) and the Total Timely Reimbursement Rates (TTRR) for both schemes. For TRR, 89% and 86% were recorded for Kassena Nankana and Builsa Schemes respectively while for TTRR, 45% and 28% were recorded respectively. Ghana's NHIS needs to reform its provider payment and claims submission and processing systems to ensure simpler and faster processes. Computerization and investment to improve the capacity to administer for both purchasers and providers will be key in any reform.

Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment.

PubMed

Panzitta, Michele; Bruno, Giorgio; Giovagnoli, Stefano; Mendicino, Francesca R; Ricci, Maurizio

2015-11-30

Health Technology Assessment (HTA) is a multidisciplinary health political instrument that evaluates the consequences, mainly clinical and economical, of a health care technology; the HTA aim is to produce and spread information on scientific and technological innovation for health political decision making process. Drug delivery systems (DDS), such as nanocarriers, are technologically complex but they have pivotal relevance in therapeutic innovation. The HTA process, as commonly applied to conventional drug evaluation, should upgrade to a full pharmaceutical assessment, considering the DDS complexity. This is useful to study more in depth the clinical outcome and to broaden its critical assessment toward pharmaceutical issues affecting the patient and not measured by the current clinical evidence approach. We draw out the expertise necessary to perform the pharmaceutical assessment and we propose a format to evaluate the DDS technological topics such as formulation and mechanism of action, physicochemical characteristics, manufacturing process. We integrated the above-mentioned three points in the Evidence Based Medicine approach, which is data source for any HTA process. In this regard, the introduction of a Pharmaceutics Expert figure in the HTA could be fundamental to grant a more detailed evaluation of medicine product characteristics and performances and to help optimizing DDS features to overcome R&D drawbacks. Some aspects of product development, such as manufacturing processes, should be part of the HTA as innovative manufacturing processes allow new products to reach more effectively patient bedside. HTA so upgraded may encourage resource allocating payers to invest in innovative technologies and providers to focus on innovative material properties and manufacturing processes, thus contributing to bring more medicines in therapy in a sustainable manner. Copyright © 2015 Elsevier B.V. All rights reserved.

Simplified Interval Observer Scheme: A New Approach for Fault Diagnosis in Instruments

PubMed Central

Martínez-Sibaja, Albino; Astorga-Zaragoza, Carlos M.; Alvarado-Lassman, Alejandro; Posada-Gómez, Rubén; Aguila-Rodríguez, Gerardo; Rodríguez-Jarquin, José P.; Adam-Medina, Manuel

2011-01-01

There are different schemes based on observers to detect and isolate faults in dynamic processes. In the case of fault diagnosis in instruments (FDI) there are different diagnosis schemes based on the number of observers: the Simplified Observer Scheme (SOS) only requires one observer, uses all the inputs and only one output, detecting faults in one detector; the Dedicated Observer Scheme (DOS), which again uses all the inputs and just one output, but this time there is a bank of observers capable of locating multiple faults in sensors, and the Generalized Observer Scheme (GOS) which involves a reduced bank of observers, where each observer uses all the inputs and m-1 outputs, and allows the localization of unique faults. This work proposes a new scheme named Simplified Interval Observer SIOS-FDI, which does not requires the measurement of any input and just with just one output allows the detection of unique faults in sensors and because it does not require any input, it simplifies in an important way the diagnosis of faults in processes in which it is difficult to measure all the inputs, as in the case of biologic reactors. PMID:22346593

Performance of ICTP's RegCM4 in Simulating the Rainfall Characteristics over the CORDEX-SEA Domain

NASA Astrophysics Data System (ADS)

Neng Liew, Ju; Tangang, Fredolin; Tieh Ngai, Sheau; Chung, Jing Xiang; Narisma, Gemma; Cruz, Faye Abigail; Phan Tan, Van; Thanh, Ngo-Duc; Santisirisomboon, Jerasron; Milindalekha, Jaruthat; Singhruck, Patama; Gunawan, Dodo; Satyaningsih, Ratna; Aldrian, Edvin

2015-04-01

The performance of the RegCM4 in simulating rainfall variations over the Southeast Asia regions was examined. Different combinations of six deep convective parameterization schemes, namely i) Grell scheme with Arakawa-Schubert closure assumption, ii) Grell scheme with Fritch-Chappel closure assumption, iii) Emanuel MIT scheme, iv) mixed scheme with Emanuel MIT scheme over the Ocean and the Grell scheme over the land, v) mixed scheme with Grell scheme over the land and Emanuel MIT scheme over the ocean and (vi) Kuo scheme, and three ocean flux treatments were tested. In order to account for uncertainties among the observation products, four different gridded rainfall products were used for comparison. The simulated climate is generally drier over the equatorial regions and slightly wetter over the mainland Indo-China compare to the observation. However, simulation with MIT cumulus scheme used over the land area consistently produces large amplitude of positive rainfall biases, although it simulates more realistic annual rainfall variations. The simulations are found less sensitive to treatment of ocean fluxes. Although the simulations produced the rainfall climatology well, all of them simulated much stronger interannual variability compare to that of the observed. Nevertheless, the time evolution of the inter-annual variations was well reproduced particularly over the eastern part of maritime continent. Over the mainland Southeast Asia (SEA), unrealistic rainfall anomalies processes were simulated. The lacking of summer season air-sea interaction results in strong oceanic forcings over the regions, leading to positive rainfall anomalies during years with warm ocean temperature anomalies. This incurs much stronger atmospheric forcings on the land surface processes compare to that of the observed. A score ranking system was designed to rank the simulations according to their performance in reproducing different aspects of rainfall characteristics. The result suggests that the simulation with Emanuel MIT convective scheme and BATs land surface scheme produces better collective performance compare to the rest of the simulations.

Global Health Innovation Technology Models.

PubMed

Harding, Kimberly

2016-01-01

Chronic technology and business process disparities between High Income, Low Middle Income and Low Income (HIC, LMIC, LIC) research collaborators directly prevent the growth of sustainable Global Health innovation for infectious and rare diseases. There is a need for an Open Source-Open Science Architecture Framework to bridge this divide. We are proposing such a framework for consideration by the Global Health community, by utilizing a hybrid approach of integrating agnostic Open Source technology and healthcare interoperability standards and Total Quality Management principles. We will validate this architecture framework through our programme called Project Orchid. Project Orchid is a conceptual Clinical Intelligence Exchange and Virtual Innovation platform utilizing this approach to support clinical innovation efforts for multi-national collaboration that can be locally sustainable for LIC and LMIC research cohorts. The goal is to enable LIC and LMIC research organizations to accelerate their clinical trial process maturity in the field of drug discovery, population health innovation initiatives and public domain knowledge networks. When sponsored, this concept will be tested by 12 confirmed clinical research and public health organizations in six countries. The potential impact of this platform is reduced drug discovery and public health innovation lag time and improved clinical trial interventions, due to reliable clinical intelligence and bio-surveillance across all phases of the clinical innovation process.

Global Health Innovation Technology Models

PubMed Central

Harding, Kimberly

2016-01-01

Chronic technology and business process disparities between High Income, Low Middle Income and Low Income (HIC, LMIC, LIC) research collaborators directly prevent the growth of sustainable Global Health innovation for infectious and rare diseases. There is a need for an Open Source-Open Science Architecture Framework to bridge this divide. We are proposing such a framework for consideration by the Global Health community, by utilizing a hybrid approach of integrating agnostic Open Source technology and healthcare interoperability standards and Total Quality Management principles. We will validate this architecture framework through our programme called Project Orchid. Project Orchid is a conceptual Clinical Intelligence Exchange and Virtual Innovation platform utilizing this approach to support clinical innovation efforts for multi-national collaboration that can be locally sustainable for LIC and LMIC research cohorts. The goal is to enable LIC and LMIC research organizations to accelerate their clinical trial process maturity in the field of drug discovery, population health innovation initiatives and public domain knowledge networks. When sponsored, this concept will be tested by 12 confirmed clinical research and public health organizations in six countries. The potential impact of this platform is reduced drug discovery and public health innovation lag time and improved clinical trial interventions, due to reliable clinical intelligence and bio-surveillance across all phases of the clinical innovation process.

Cultivating a Grassroots Aerospace Innovation Culture at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

D'Souza, Sarah; Sanchez, Hugo; Lewis, Ryan

2017-01-01

This paper details the adaptation of specific 'knowledge production' methods to implement a first of its kind, grassroots event that provokes a cultural change in how the NASA Ames civil servant community engages in the creation and selection of innovative ideas. Historically, selection of innovative proposals at NASA Ames Research Center is done at the highest levels of management, isolating the views and perspectives of the larger civil servant community. Additionally, NASA innovation programs are typically open to technical organizations and do not engage non-technical organizations to bring forward innovative processes/business practices. Finally, collaboration on innovative ideas and associated solutions tend to be isolated to organizational silos. In this environment, not all Ames employees feel empowered to innovate and opportunities for employee collaboration are limited. In order to address these issues, the 'innovation contest' method was adapted to create the NASA Ames Innovation Fair, a unique, grassroots innovation opportunity for the civil servant community. The Innovation Fair consisted of a physical event with a virtual component. The physical event provided innovators the opportunity to collaborate and pitch their innovations to the NASA Ames community. The civil servant community then voted for the projects that they viewed as innovative and would contribute to NASA's core mission, making this event a truly grassroots effort. The Innovation Fair website provided a location for additional knowledge sharing, discussion, and voting. On March 3rd, 2016, the 'First Annual NASA Ames Innovation Fair' was held with 49 innovators and more than 300 participants collaborating and/or voting for the best innovations. Based on the voting results, seven projects were awarded seed funding for projects ranging from innovative cost models to innovations in aerospace technology. Surveys of both innovators and Fair participants show the Innovation Fair was successful in fostering cross-organizational collaborations, soliciting participation of non-technical innovations, and increasing employee engagement in influencing the future of NASA Ames Research Center. The grassroots component of the Innovation Fair has been bench marked by the agency as a solid foundation for increasing employee engagement in the development of game changing aerospace technology and processes in support of NASA's mission.

Z-schematic water splitting by the synergistic effect of a type-II heterostructure and a highly efficient oxygen evolution catalyst

NASA Astrophysics Data System (ADS)

Li, Xiaoyun; Hu, Haihua; Xu, Lingbo; Cui, Can; Qian, Degui; Li, Shuang; Zhu, Wenzhe; Wang, Peng; Lin, Ping; Pan, Jiaqi; Li, Chaorong

2018-05-01

Artificial Z-scheme system inspired by the natural photosynthesis in green plants has attracted extensive attention owing to its advantages such as simultaneously wide range light absorption, highly efficient charge separation and strong redox ability. In this paper, we report the synthesis of a novel all-solid-state direct Z-scheme photocatalyst of Ag3PO4/CeO2/TiO2 by depositing Ag3PO4 nanoparticles (NPs) on CeO2/TiO2 hierarchical branched nanowires (BNWs), where the CeO2/TiO2 BNWs act as a novel substrate for the well dispersed nano-size Ag3PO4. The Ag3PO4/CeO2/TiO2 photocatalyst exhibits excellent ability of photocatalytic oxygen evolution from pure water splitting. It is suggested that the Z-scheme charge transfer route between CeO2/TiO2 and Ag3PO4 improves the redox ability. On the other hand, the cascade energy level alignment in CeO2/TiO2 BNWs expedites the spatial charge separation, and hence suppresses photocatalytic backward reaction. However, it is difficult to realize a perfect excitation balance in Ag3PO4/CeO2/TiO2 and the composite still surfers photo-corrosion in photocatalysis reaction. Nevertheless, our results provide an innovative strategy of constructing a Z-scheme system from a type-II heterostructure and a highly efficient oxygen evolution catalyst.

Understanding innovators' experiences of barriers and facilitators in implementation and diffusion of healthcare service innovations: a qualitative study

PubMed Central

2011-01-01

Background Healthcare service innovations are considered to play a pivotal role in improving organisational efficiency and responding effectively to healthcare needs. Nevertheless, healthcare organisations encounter major difficulties in sustaining and diffusing innovations, especially those which concern the organisation and delivery of healthcare services. The purpose of the present study was to explore how healthcare innovators of process-based initiatives perceived and made sense of factors that either facilitated or obstructed the innovation implementation and diffusion. Methods A qualitative study was designed. Fifteen primary and secondary healthcare organisations in the UK, which had received health service awards for successfully generating and implementing service innovations, were studied. In-depth, semi structured interviews were conducted with the organisational representatives who conceived and led the development process. The data were recorded, transcribed and thematically analysed. Results Four main themes were identified in the analysis of the data: the role of evidence, the function of inter-organisational partnerships, the influence of human-based resources, and the impact of contextual factors. "Hard" evidence operated as a proof of effectiveness, a means of dissemination and a pre-requisite for the initiation of innovation. Inter-organisational partnerships and people-based resources, such as champions, were considered an integral part of the process of developing, establishing and diffusing the innovations. Finally, contextual influences, both intra-organisational and extra-organisational were seen as critical in either impeding or facilitating innovators' efforts. Conclusions A range of factors of different combinations and co-occurrence were pointed out by the innovators as they were reflecting on their experiences of implementing, stabilising and diffusing novel service initiatives. Even though the innovations studied were of various contents and originated from diverse organisational contexts, innovators' accounts converged to the significant role of the evidential base of success, the inter-personal and inter-organisational networks, and the inner and outer context. The innovators, operating themselves as important champions and being often willing to lead constructive efforts of implementation to different contexts, can contribute to the promulgation and spread of the novelties significantly. PMID:22176739

Understanding innovators' experiences of barriers and facilitators in implementation and diffusion of healthcare service innovations: a qualitative study.

PubMed

Barnett, Julie; Vasileiou, Konstantina; Djemil, Fayika; Brooks, Laurence; Young, Terry

2011-12-16

Healthcare service innovations are considered to play a pivotal role in improving organisational efficiency and responding effectively to healthcare needs. Nevertheless, healthcare organisations encounter major difficulties in sustaining and diffusing innovations, especially those which concern the organisation and delivery of healthcare services. The purpose of the present study was to explore how healthcare innovators of process-based initiatives perceived and made sense of factors that either facilitated or obstructed the innovation implementation and diffusion. A qualitative study was designed. Fifteen primary and secondary healthcare organisations in the UK, which had received health service awards for successfully generating and implementing service innovations, were studied. In-depth, semi structured interviews were conducted with the organisational representatives who conceived and led the development process. The data were recorded, transcribed and thematically analysed. Four main themes were identified in the analysis of the data: the role of evidence, the function of inter-organisational partnerships, the influence of human-based resources, and the impact of contextual factors. "Hard" evidence operated as a proof of effectiveness, a means of dissemination and a pre-requisite for the initiation of innovation. Inter-organisational partnerships and people-based resources, such as champions, were considered an integral part of the process of developing, establishing and diffusing the innovations. Finally, contextual influences, both intra-organisational and extra-organisational were seen as critical in either impeding or facilitating innovators' efforts. A range of factors of different combinations and co-occurrence were pointed out by the innovators as they were reflecting on their experiences of implementing, stabilising and diffusing novel service initiatives. Even though the innovations studied were of various contents and originated from diverse organisational contexts, innovators' accounts converged to the significant role of the evidential base of success, the inter-personal and inter-organisational networks, and the inner and outer context. The innovators, operating themselves as important champions and being often willing to lead constructive efforts of implementation to different contexts, can contribute to the promulgation and spread of the novelties significantly.

A scheme for recording a fast process at nanosecond scale by using digital holographic interferometry with continuous wave laser

NASA Astrophysics Data System (ADS)

Wang, Jun; Zhao, Jianlin; Di, Jianglei; Jiang, Biqiang

2015-04-01

A scheme for recording fast process at nanosecond scale by using digital holographic interferometry with continuous wave (CW) laser is described and demonstrated experimentally, which employs delayed-time fibers and angular multiplexing technique and can realize the variable temporal resolution at nanosecond scale and different measured depths of object field at certain temporal resolution. The actual delay-time is controlled by two delayed-time fibers with different lengths. The object field information in two different states can be simultaneously recorded in a composite hologram. This scheme is also suitable for recording fast process at picosecond scale, by using an electro-optic modulator.

Method of Cross-Linking Aerogels Using a One-Pot Reaction Scheme

NASA Technical Reports Server (NTRS)

Meador, Ann B.; Capadona, Lynn A.

2008-01-01

A document discusses a new, simplified method for cross-linking silica and other oxide aerogels, with a polymeric material to increase strength of such materials without adversely affecting porosity or low density. This innovation introduces the polymer precursor into the sol before gelation either as an agent, which co-reacts with the oxide gel, or as soluble polymer precursors, which do not interact with the oxide gel in any way. Subsequent exposure to heat, light, catalyst or other method of promoting polymerization causes cross-linking without any additional infiltration steps.

Quantum Private Comparison Protocol with Linear Optics

NASA Astrophysics Data System (ADS)

Luo, Qing-bin; Yang, Guo-wu; She, Kun; Li, Xiaoyu

2016-12-01

In this paper, we propose an innovative quantum private comparison(QPC) protocol based on partial Bell-state measurement from the view of linear optics, which enabling two parties to compare the equality of their private information with the help of a semi-honest third party. Partial Bell-state measurement has been realized by using only linear optical elements in experimental measurement-device-independent quantum key distribution(MDI-QKD) schemes, which makes us believe that our protocol can be realized in the near future. The security analysis shows that the participants will not leak their private information.

Coronography with a dynamic hologram

NASA Astrophysics Data System (ADS)

Ricci, D.; Le Coroller, H.; Piron, P.

2010-10-01

An innovative solution to improve the performances of coronagraphs consists in adding, in the optical scheme, a dynamic hologram removing most of the residual speckle starlight. Our simulations show that the detection limit in the flux ratio between a host star and a very near planet, in the case of wavefront bumpiness imperfections at lambda/20 (resp. lambda/100), improves over a factor 1000 (resp. 10000) when equipped with a hologram, allowing to direct image an exo-Earth at a distance of 11 parsec with a ∼6.5m space telescope.

Note: Focus error detection device for thermal expansion-recovery microscopy (ThERM).

PubMed

Domené, E A; Martínez, O E

2013-01-01

An innovative focus error detection method is presented that is only sensitive to surface curvature variations, canceling both thermoreflectance and photodefelection effects. The detection scheme consists of an astigmatic probe laser and a four-quadrant detector. Nonlinear curve fitting of the defocusing signal allows the retrieval of a cutoff frequency, which only depends on the thermal diffusivity of the sample and the pump beam size. Therefore, a straightforward retrieval of the thermal diffusivity of the sample is possible with microscopic lateral resolution and high axial resolution (~100 pm).

Synthesis of strong SiV photoluminescent diamond particles on silica optical fiber by chemical vapor deposition

NASA Astrophysics Data System (ADS)

Yang, Zongchun; Mei, Yingshuang; Chen, Chengke; Ruan, Yinlan; Hu, Xiaojun

2018-03-01

Not Available Project supported by the National Natural Science Foundation of China (Grant Nos. 50972129 and 50602039), the International Science Technology Cooperation Program of China (Grant No. 2014DFR51160), the National Key Research and Development Program of China (Grant No. 2016YFE0133200), European Unionʼs Horizon 2020 Research and Innovation Staff Exchange (RISE) Scheme (Grant No. 734578), and the One Belt and One Road International Cooperation Project from Key Research and Development Program of Zhejiang Province, China (Grant No. 2018C04021).

Business model configuration and dynamics for technology commercialization in mature markets.

PubMed

Flammini, Serena; Arcese, Gabriella; Lucchetti, Maria Claudia; Mortara, Letizia

2017-01-01

The food industry is a well-established and complex industry. New entrants attempting to penetrate it via the commercialization of a new technological innovation could face high uncertainty and constraints. The capability to innovate through collaboration and to identify suitable strategies and innovative business models (BMs) can be particularly important for bringing a technological innovation to this market. However, although the potential for these capabilities has been advocated, we still lack a complete understanding of how new ventures could support the technology commercialization process via the development of BMs. The paper aims to discuss these issues. To address this gap, this paper builds a conceptual framework that knits together the different bodies of extant literature (i.e. entrepreneurship, strategy and innovation) to analyze the BM innovation processes associated with the exploitation of emerging technologies; determines the suitability of the framework using data from the exploratory case study of IT IS 3D - a firm which has started to exploit 3D printing in the food industry; and improves the initial conceptual framework with the findings that emerged in the case study. From this analysis it emerged that: companies could use more than one BM at a time; hence, BM innovation processes could co-exist and be run in parallel; the facing of high uncertainty might lead firms to choose a closed and/or a familiar BM, while explorative strategies could be pursued with open BMs; significant changes in strategies during the technology commercialization process are not necessarily reflected in a radical change in the BM; and firms could deliberately adopt interim strategies and BMs as means to identify the more suitable ones to reach the market. This case study illustrates how firms could innovate the processes of their BM development to face the uncertainties linked with the entry into a mature and highly conservative industry (food).

INTELLECTUAL PROPERTY IN THE TWENTY-FIRST CENTURY: WILL THE DEVELOPING COUNTRIES LEAD OR FOLLOW?

PubMed Central

Reichman, Jerome H.

2010-01-01

Developing countries, particularly the BRIC countries of Brazil, Russia, India, and China, should accommodate their national systems of innovation to the worldwide intellectual property (IP) regime emerging after the adoption of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) in a way that maximizes global economic welfare in the foreseeable future. As many developed countries’ experience demonstrates, badly configured, over-protectionist IP regimes stifle innovation by making inputs to future innovation too costly and too cumbersome to sustain over time. More carefully considered IP regimes, however, are an important way to protect innovative small- and medium-sized firms from predatory, larger competitors. The challenge is for emerging economies to capture the benefits of IP without importing the serious problems that developed countries have themselves failed to solve. Emerging economies can attain this balance by pursuing a policy of counter-harmonization in which they take advantage of existing exemptions in international agreements governing IP to establish regional, local, and international practices that promote more innovative, flexible uses of IP. Such practices include a research exemption for experimental uses of IP, government imposed nonexclusive licensing, anti-blocking provisions, an essential facilities doctrine, and compulsory licenses. Additional tools include an ex ante regime of compensatory liability rules for small scale innovation and sensible exceptions, particularly for science as well as general fair use provisions, to the exclusive rights of domestic copyright laws. Emerging economies will have to overcome strong economic pressure to accept more restrictive IP regimes as part of free trade agreements as well as a lack of technical expertise and internal government coordination. However, emerging economies have already accrued enough experience to be aware of the strengths and weaknesses of various IP schemes and their own ability to tailor IP to local needs. Developing countries will need to take advantage of that experience and defend innovative practices at international dispute resolution forums. Through creative, determined efforts, the developing countries can avoid other countries’ IP excesses while establishing the kind of IP norms that address the real conditions of creativity and innovation in today’s digitally empowered universe of scientific discourse. PMID:21423816

INTELLECTUAL PROPERTY IN THE TWENTY-FIRST CENTURY: WILL THE DEVELOPING COUNTRIES LEAD OR FOLLOW?

PubMed

Reichman, Jerome H

2009-01-31

Developing countries, particularly the BRIC countries of Brazil, Russia, India, and China, should accommodate their national systems of innovation to the worldwide intellectual property (IP) regime emerging after the adoption of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) in a way that maximizes global economic welfare in the foreseeable future. As many developed countries' experience demonstrates, badly configured, over-protectionist IP regimes stifle innovation by making inputs to future innovation too costly and too cumbersome to sustain over time. More carefully considered IP regimes, however, are an important way to protect innovative small- and medium-sized firms from predatory, larger competitors. The challenge is for emerging economies to capture the benefits of IP without importing the serious problems that developed countries have themselves failed to solve. Emerging economies can attain this balance by pursuing a policy of counter-harmonization in which they take advantage of existing exemptions in international agreements governing IP to establish regional, local, and international practices that promote more innovative, flexible uses of IP. Such practices include a research exemption for experimental uses of IP, government imposed nonexclusive licensing, anti-blocking provisions, an essential facilities doctrine, and compulsory licenses. Additional tools include an ex ante regime of compensatory liability rules for small scale innovation and sensible exceptions, particularly for science as well as general fair use provisions, to the exclusive rights of domestic copyright laws. Emerging economies will have to overcome strong economic pressure to accept more restrictive IP regimes as part of free trade agreements as well as a lack of technical expertise and internal government coordination. However, emerging economies have already accrued enough experience to be aware of the strengths and weaknesses of various IP schemes and their own ability to tailor IP to local needs. Developing countries will need to take advantage of that experience and defend innovative practices at international dispute resolution forums. Through creative, determined efforts, the developing countries can avoid other countries' IP excesses while establishing the kind of IP norms that address the real conditions of creativity and innovation in today's digitally empowered universe of scientific discourse.

A Phenomenographic Investigation of the Ways Engineering Students Experience Innovation

NASA Astrophysics Data System (ADS)

Fila, Nicholas David

Innovation has become an important phenomenon in engineering and engineering education. By developing novel, feasible, viable, and valued solutions to complex technical and human problems, engineers support the economic competitiveness of organizations, make a difference in the lives of users and other stakeholders, drive societal and scientific progress, and obtain key personal benefits. Innovation is also a complex phenomenon. It occurs across a variety of contexts and domains, encompasses numerous phases and activities, and requires unique competency profiles. Despite this complexity, many studies in engineering education focus on specific aspects (e.g., engineering students' abilities to generate original concepts during idea generation), and we still know little about the variety of ways engineering students approach and understand innovation. This study addresses that gap by asking: 1. What are the qualitatively different ways engineering students experience innovation during their engineering projects? 2. What are the structural relationships between the ways engineering students experience innovation? This study utilized phenomenography, a qualitative research method, to explore the above research questions. Thirty-three engineering students were recruited to ensure thorough coverage along four factors suggested by the literature to support differences related to innovation: engineering project experience, academic major, year in school, and gender. Each participant completed a 1-2 hour, semi-structured interview that focused on experiences with and conceptions of innovation. Whole transcripts were analyzed using an eight-stage, iterative, and comparative approach meant to identify a limited number of categories of description (composite ways of experiencing innovation comprised of the experiences of several participants), and the structural relationships between these categories. Phenomenographic analysis revealed eight categories of description that were structured in a semi-hierarchical, two-dimensional outcome space. The first four categories demonstrated a progression toward greater comprehensiveness in both process and focus dimensions. In the process dimension, subsequent categories added increasingly preliminary innovation phases: idea realization, idea generation, problem scoping, and problem finding. In the focus dimension, subsequent categories added key areas engineers considered during innovation: technical, human, and enterprise. The final four categories each incorporated all previous process phases and focus areas, but prioritized different focus areas in sophisticated ways and acknowledged a macro-iterative cycle, i.e., an understanding of how the processes within a single innovation project built upon and contributed to past and future innovation projects. These results demonstrate important differences between engineering students and suggest how they may come to experience innovation in increasingly comprehensive ways. A framework based on the results can be used by educators and researchers to support more robust educational offerings and nuanced research designs that reflect these differences.

Determinants of innovation within health care organizations: literature review and Delphi study.

PubMed

Fleuren, Margot; Wiefferink, Karin; Paulussen, Theo

2004-04-01

When introducing innovations to health care, it is important to gain insight into determinants that may facilitate or impede the introduction, in order to design an appropriate strategy for introducing the innovation. To obtain an overview of determinants of innovations in health care organizations, we carried out a literature review and a Delphi study. The Delphi study was intended to achieve consensus among a group of implementation experts on determinants identified from the literature review. We searched 11 databases for articles published between 1990 and 2000. The keywords varied according to the specific database. We also searched for free text. Forty-four implementation experts (implementation researchers, programme managers, and implementation consultants/advisors) participated in the Delphi study. The following studies were selected: (i) studies describing innovation processes, and determinants thereof, in health care organizations; (ii) studies where the aim of the innovations was to change the behaviour of health professionals; (iii) studies where the health care organizations provided direct patient care; and (iv) studies where only empirical studies were included. Two researchers independently selected the abstracts and analysed the articles. The determinants were divided into four categories: characteristics of the environment, characteristics of the organization, characteristics of the user (health professional), and characteristics of the innovation. When analysing the determinants, a distinction was made between systematically designed and non-systematically designed studies. In a systematic study, a determinant analysis was performed and the innovation strategy was adapted to these determinants. Furthermore, the determinants were associated with the degree of implementation, and both users and non-users of the innovation were asked about possible determinants. In the Delphi study, consensus was defined as agreement among 75% of the experts on both the influence of a determinant and the direction towards which that influence tended (i.e. facilitating, impeding, or neutral). From the initial 2239 abstracts, 57 studies were retrieved and 49 determinants were identified that affected (impeded or facilitated) the innovation process. The experts identified one other determinant. Seventeen studies had a more-or-less systematic design; the others did not. After three rounds, consensus was reached on the influence of 49 out of 50 determinants. The results of the literature review matched those found in the Delphi study, and 50 potentially relevant determinants of innovation processes were identified. Many of the innovation studies had several methodological flaws, such as not adjusting innovation strategies to relevant determinants of the innovation process, or that data on determinants were gathered only from non-users. Furthermore, the degree of implementation was evaluated in several ways, which made comparison difficult.

Quackery or quality: the ethicolegal basis for a legislative framework for medical innovation.

PubMed

Samanta, Jo; Samanta, Ash

2015-06-01

Innovative therapy is a matter of recent public interest, particularly following Lord Saatchi's Medical Innovation Bill. The purpose of the Bill is to encourage responsible innovation in medical treatment. We argue for the need to achieve a balance between the risks of medical innovation and patient safety considerations. We make the case for statutory regulation of medical innovation on the basis of responsible innovation, choice and patient-centred care. At the heart of regulation of medical innovation is care delivered by a process which is accountable, transparent and allows full consideration of all relevant matters. This paper proposes a two-stage test (to assess applicability of medical innovation as well as suitability for the choice of intervention to be undertaken). It is suggested that this model would provide safeguards for patients as well as define limits for doctors in the context of innovative therapy. Implementation and application of such therapy must be underpinned by due process and governance oversight, which could be provided through context-specific professional peer review. A combination of these ethicolegal principles would permit responsible medical innovation and maximise benefit in terms of therapy and patient-centred care. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Innovation implementation in the public sector: an integration of institutional and collective dynamics.

PubMed

Choi, Jin Nam; Chang, Jae Yoon

2009-01-01

The present study integrates institutional factors and employee-based collective processes as predictors of 2 key implementation outcomes: implementation effectiveness and innovation effectiveness (Klein, Conn, & Sorra, 2001). Specifically, the authors proposed that institutional factors shape employees' collective implementation efficacy and innovation acceptance. The authors further hypothesized that these employee-based collective processes mediate the effects of institutional factors on implementation outcomes. This integrative framework was examined in the context of 47 agencies and ministries of the Korean Government that were implementing a process innovation called E-Government. Three-wave longitudinal data were collected from 60 external experts and 1,732 government employees. The results reveal the importance of management support for collective implementation efficacy, which affected employees' collective acceptance of the innovation. As hypothesized, these collective employee dynamics mediated the effects of institutional enablers on successful implementation as well as the amount of long-term benefit that accrued to the agencies and ministries. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

Opening up the Agile Innovation Process

NASA Astrophysics Data System (ADS)

Conboy, Kieran; Donnellan, Brian; Morgan, Lorraine; Wang, Xiaofeng

The objective of this panel is to discuss how firms can operate both an open and agile innovation process. In an era of unprecedented changes, companies need to be open and agile in order to adapt rapidly and maximize their innovation processes. Proponents of agile methods claim that one of the main distinctions between agile methods and their traditional bureaucratic counterparts is their drive toward creativity and innovation. However, agile methods are rarely adopted in their textbook, "vanilla" format, and are usually adopted in part or are tailored or modified to suit the organization. While we are aware that this happens, there is still limited understanding of what is actually happening in practice. Using innovation adoption theory, this panel will discuss the issues and challenges surrounding the successful adoption of agile practices. In addition, this panel will report on the obstacles and benefits reported by over 20 industrial partners engaged in a pan-European research project into agile practices between 2006 and 2009.

Detection-enhanced steady state entanglement with ions.

PubMed

Bentley, C D B; Carvalho, A R R; Kielpinski, D; Hope, J J

2014-07-25

Driven dissipative steady state entanglement schemes take advantage of coupling to the environment to robustly prepare highly entangled states. We present a scheme for two trapped ions to generate a maximally entangled steady state with fidelity above 0.99, appropriate for use in quantum protocols. Furthermore, we extend the scheme by introducing detection of our dissipation process, significantly enhancing the fidelity. Our scheme is robust to anomalous heating and requires no sympathetic cooling.