NPS transportation innovative finance options

DOT National Transportation Integrated Search

2013-05-01

This paper provides a summary of innovative transportation finance techniques and discusses their applicability to the National Park Service (NPS). The primary finding of this analysis is that while NPS is engaging in innovative finance techniques su...

Medical laser application: translation into the clinics

NASA Astrophysics Data System (ADS)

Sroka, Ronald; Stepp, Herbert; Hennig, Georg; Brittenham, Gary M.; Rühm, Adrian; Lilge, Lothar

2015-06-01

Medical laser applications based on widespread research and development is a very dynamic and increasingly popular field from an ecological as well as an economic point of view. Conferences and personal communication are necessary to identify specific requests and potential unmet needs in this multi- and interdisciplinary discipline. Precise gathering of all information on innovative, new, or renewed techniques is necessary to design medical devices for introduction into clinical applications and finally to become established for routine treatment or diagnosis. Five examples of successfully addressed clinical requests are described to show the long-term endurance in developing light-based innovative clinical concepts and devices. Starting from laboratory medicine, a noninvasive approach to detect signals related to iron deficiency is shown. Based upon photosensitization, fluorescence-guided resection had been discovered, opening the door for photodynamic approaches for the treatment of brain cancer. Thermal laser application in the nasal cavity obtained clinical acceptance by the introduction of new laser wavelengths in clinical consciousness. Varicose veins can be treated by innovative endoluminal treatment methods, thus reducing side effects and saving time. Techniques and developments are presented with potential for diagnosis and treatment to improve the clinical situation for the benefit of the patient.

[Globalization of acupuncture technology innovation: a quantitative analysis based on acupuncture patents in the U.S.A].

PubMed

Pan, Wei; Hu, Yuan-Jia; Wang, Yi-Tao

2011-08-01

The structure of international flow of acupuncture knowledge was explored in this article so as to promote the globalization of acupuncture technology innovation. Statistical methods were adopted to reveal geographical distribution of acupuncture patents in the U.S.A. and the influencing factors of cumulative advantage of acupuncture techniques as well as innovation value of application of acupuncture patents. Social network analysis was also utilized to establish a global innovation network of acupuncture technology. The result shows that the cumulative strength on acupuncture technology correlates with the patent retention period. The innovative value of acupuncture invention correlates with the frequency of patent citation. And the U. S. A. and Canada seize central positions in the global acupuncture information and technology delivery system.

Innovative hyperspectral imaging-based techniques for quality evaluation of fruits and vegetables: a review

USDA-ARS?s Scientific Manuscript database

New, non-destructive sensing techniques for fast and more effective quality assessment of fruits and vegetables are needed to meet the ever-increasing consumer demand for better, more consistent and safer food products. Over the past 15 years, hyperspectral imaging has emerged as a new generation of...

Alternative evaluation of innovations’ effectiveness in mechanical engineering

NASA Astrophysics Data System (ADS)

Puryaev, A. S.

2017-09-01

The aim of present work is approbation of the developed technique for assessing innovations’ effectiveness. We demonstrate an alternative assessment of innovations’ effectiveness (innovation projects) in mechanical engineering on illustrative example. It is proposed as an alternative to the traditional method technique based on the value concept and the method of “Cash flow”.

Innovative and Successful Approaches to Improving Care Transitions From Hospital to Home

PubMed Central

Labson, Margherita C.

2015-01-01

Abstract Effective transitions to home care have been identified as among the factors leading to reducing hospital readmissions within 30 days of discharge and improvements on various other quality measures. Innovative applications of published evidence-based models and best practices designed to improve care transitions have been implemented in various settings across the country in an effort to enhance quality performance. For this article, The Joint Commission collected a series of case examples to examine how evidence-based innovations in care transitions are reducing readmissions and improving other quality outcomes. The organizations providing the case examples were interviewed and asked to provide performance data demonstrating quality improvement, as well as information about their care processes and data-gathering techniques. Their innovative approaches are reducing hospital readmissions; improving patient safety, satisfaction, and engagement; and contributing to other positive outcomes. PMID:25654457

The Evolvement of Automobile Steering System Based on TRIZ

NASA Astrophysics Data System (ADS)

Zhao, Xinjun; Zhang, Shuang

Products and techniques pass through a process of birth, growth, maturity, death and quit the stage like biological evolution process. The developments of products and techniques conform to some evolvement rules. If people know and hold these rules, they can design new kind of products and forecast the develop trends of the products. Thereby, enterprises can grasp the future technique directions of products, and make product and technique innovation. Below, based on TRIZ theory, the mechanism evolvement, the function evolvement and the appearance evolvement of automobile steering system had been analyzed and put forward some new ideas about future automobile steering system.

Solution mechanism guide: implementing innovation within a research & development organization.

PubMed

Keeton, Kathryn E; Richard, Elizabeth E; Davis, Jeffrey R

2014-10-01

In order to create a culture more open to novel problem-solving mechanisms, NASA's Human Health and Performance Directorate (HH&P) created a strategic knowledge management tool that educates employees about innovative problem-solving techniques, the Solution Mechanism Guide (SMG). The SMG is a web-based, interactive guide that leverages existing and innovative problem-solving methods and presents this information as a unique user experience so that the employee is empowered to make the best decision about which problem-solving tool best meets their needs. By integrating new and innovative methods with existing problem solving tools, the SMG seamlessly introduces open innovation and collaboration concepts within HH&P to more effectively address human health and performance risks. This commentary reviews the path of creating a more open and innovative culture within HH&P and the process and development steps that were taken to develop the SMG.

Innovative smart micro sensors for Army weaponry applications

NASA Astrophysics Data System (ADS)

Ruffin, Paul B.; Brantley, Christina; Edwards, Eugene

2008-03-01

Micro sensors offer the potential solution to cost, size, and weight issues associated with smart networked sensor systems designed for environmental/missile health monitoring and rocket out-gassing/fuel leak detection, as well as situational awareness on the battlefield. In collaboration with the University of Arkansas (Fayetteville), University of Alabama (Tuscaloosa and Birmingham), Alabama A&M University (Normal), and Streamline Automation (Huntsville, AL), scientists and engineers at the Army Aviation & Missile Research, Development, and Engineering Center (AMRDEC) are investigating several nano-based technologies to solve the problem of sensing extremely small levels of toxic gases associated with both chemical warfare agents (in air and liquids) and potential rocket motor leaks. Innovative techniques are being devised to adapt voltammetry, which is a well established technique for the detection and quantification of substances dissolved in liquids, to low-cost micro sensors for detecting airborne chemical agents and potential missile propellant leakages. In addition, a surface enhanced Raman scattering (SERS) technique, which enhances Raman scattered light by excitation of surface plasmons on nanoporous metal surfaces (nanospheres), is being investigated to develop novel smart sensors for the detection of chemical agents (including rocket motor out-gassing) and potential detection of home-made explosive devices. In this paper, results are delineated that are associated with experimental studies, which are conducted for the aforementioned cases and for several other nano-based technology approaches. The design challenges of each micro sensor technology approach are discussed. Finally, a comparative analysis of the various innovative micro-sensor techniques is provided.

Innovative research on the group teaching mode based on the LabVIEW virtual environment

NASA Astrophysics Data System (ADS)

Liang, Pei; Huang, Jie; Gong, Hua-ping; Dong, Qian-min; Dong, Yan-yan; Sun, Cai-xia

2017-08-01

This paper discusses the widely existing problems of increasing demand of professional engineer in electronic science major and the backward of the teaching mode at present. From one specialized course "Virtual Instrument technique and LABVIEW programming", we explore the new group-teaching mode based on the Virtual Instrument technique, and then the Specific measures and implementation procedures and effect of this teaching mode summarized in the end.

An innovative Yb-based ultrafast deep ultraviolet source for time-resolved photoemission experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boschini, F.; Hedayat, H.; Dallera, C.

2014-12-15

Time- and angle-resolved photoemission spectroscopy is a powerful technique to study ultrafast electronic dynamics in solids. Here, an innovative optical setup based on a 100-kHz Yb laser source is presented. Exploiting non-collinear optical parametric amplification and sum-frequency generation, ultrashort pump (hν = 1.82 eV) and ultraviolet probe (hν = 6.05 eV) pulses are generated. Overall temporal and instrumental energy resolutions of, respectively, 85 fs and 50 meV are obtained. Time- and angle-resolved measurements on BiTeI semiconductor are presented to show the capabilities of the setup.

Innovating for quality and value: Utilizing national quality improvement programs to identify opportunities for responsible surgical innovation.

PubMed

Woo, Russell K; Skarsgard, Erik D

2015-06-01

Innovation in surgical techniques, technology, and care processes are essential for improving the care and outcomes of surgical patients, including children. The time and cost associated with surgical innovation can be significant, and unless it leads to improvements in outcome at equivalent or lower costs, it adds little or no value from the perspective of the patients, and decreases the overall resources available to our already financially constrained healthcare system. The emergence of a safety and quality mandate in surgery, and the development of the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) allow needs-based surgical care innovation which leads to value-based improvement in care. In addition to general and procedure-specific clinical outcomes, surgeons should consider the measurement of quality from the patients' perspective. To this end, the integration of validated Patient Reported Outcome Measures (PROMs) into actionable, benchmarked institutional outcomes reporting has the potential to facilitate quality improvement in process, treatment and technology that optimizes value for our patients and health system. Copyright © 2015 Elsevier Inc. All rights reserved.

Novel diagnostic techniques for celiac disease.

PubMed

Kurppa, Kalle; Taavela, Juha; Saavalainen, Päivi; Kaukinen, Katri; Lindfors, Katri

2016-07-01

The diagnosis of celiac disease has long been based on the demonstration of gluten-induced small-bowel mucosal damage. However, due to the constantly increasing disease prevalence and limitations in the histology-based criteria there is a pressure towards more serology-based diagnostics. The serological tools are being improved and new non-invasive methods are being developed, but the constantly refined endoscopic and histologic techniques may still prove helpful. Moreover, growing understanding of the disease pathogenesis has led researchers to suggest completely novel approaches to celiac disease diagnostics regardless of disease activity. In this review, we will elucidate the most recent development and possible future innovations in the diagnostic techniques for celiac disease.

Education and Training for Sustainable Tourism: Problems, Possibilities and Cautious First Steps.

ERIC Educational Resources Information Center

Gough, Stephen; Scott, William

1999-01-01

Advances a possible theoretical approach to education for sustainable tourism and describes a small-scale research project based on this approach. Seeks to integrate education for sustainable tourism into an established management curriculum using an innovative technique based on the idea of an adaptive concept. (Author/CCM)

Applying Case-Based Reasoning in Knowledge Management to Support Organizational Performance

ERIC Educational Resources Information Center

Wang, Feng-Kwei

2006-01-01

Research and practice in human performance technology (HPT) has recently accelerated the search for innovative approaches to supplement or replace traditional training interventions for improving organizational performance. This article examines a knowledge management framework built upon the theories and techniques of case-based reasoning (CBR)…

Innovation and behavioral flexibility in wild redfronted lemurs (Eulemur rufifrons).

PubMed

Huebner, Franziska; Fichtel, Claudia

2015-05-01

Innovations and problem-solving abilities can provide animals with important ecological advantages as they allow individuals to deal with novel social and ecological challenges. Innovation is a solution to a novel problem or a novel solution to an old problem, with the latter being especially difficult. Finding a new solution to an old problem requires individuals to inhibit previously applied solutions to invent new strategies and to behave flexibly. We examined the role of experience on cognitive flexibility to innovate and to find new problem-solving solutions with an artificial feeding task in wild redfronted lemurs (Eulemur rufifrons). Four groups of lemurs were tested with feeding boxes, each offering three different techniques to extract food, with only one technique being available at a time. After the subjects learned a technique, this solution was no longer successful and subjects had to invent a new technique. For the first transition between task 1 and 2, subjects had to rely on their experience of the previous technique to solve task 2. For the second transition, subjects had to inhibit the previously learned technique to learn the new task 3. Tasks 1 and 2 were solved by most subjects, whereas task 3 was solved by only a few subjects. In this task, besides behavioral flexibility, especially persistence, i.e., constant trying, was important for individual success during innovation. Thus, wild strepsirrhine primates are able to innovate flexibly, suggesting a general ecological relevance of behavioral flexibility and persistence during innovation and problem solving across all primates.

Why bundled payments could drive innovation: an example from interventional oncology.

PubMed

Steele, Joseph R; Jones, A Kyle; Ninan, Elizabeth P; Clarke, Ryan K; Odisio, Bruno C; Avritscher, Rony; Murthy, Ravi; Mahvash, Armeen

2015-03-01

Some have suggested that the current fee-for-service health care payment system in the United States stifles innovation. However, there are few published examples supporting this concept. We implemented an innovative temporary balloon occlusion technique for yttrium 90 radioembolization of nonresectable liver cancer. Although our balloon occlusion technique was associated with similar patient outcomes, lower cost, and faster procedure times compared with the standard-of-care coil embolization technique, our technique failed to gain widespread acceptance. Financial analysis revealed that because the balloon occlusion technique avoided a procedural step associated with a lucrative Current Procedural Terminology billing code, this new technique resulted in a significant decrease in hospital and physician revenue in the current fee-for-service payment system, even though the new technique would provide a revenue enhancement through cost savings in a bundled payment system. Our analysis illustrates how in a fee-for-service payment system, financial disincentives can stifle innovation and advancement of health care delivery. Copyright © 2015 by American Society of Clinical Oncology.

Innovative hyperspectral imaging (HSI) based techniques applied to end-of-life concrete drill core characterization for optimal dismantling and materials recovery

NASA Astrophysics Data System (ADS)

Bonifazi, Giuseppe; Picone, Nicoletta; Serranti, Silvia

2015-02-01

The reduction of EOL concrete disposal in landfills, together with a lower exploitation of primary raw materials, generates a strong interest to develop, set-up and apply innovative technologies to maximize Construction and Demolition Waste (C&DW) conversion into useful secondary raw materials. Such a goal can be reached starting from a punctual in-situ efficient characterization of the objects to dismantle in order to develop demolition actions aimed to set up innovative mechanical-physical processes to recover the different materials and products to recycle. In this paper an innovative recycling-oriented characterization strategy based on HyperSpectral Imaging (HSI) is described in order to identify aggregates and mortar in drill core samples from end-of-life concrete. To reach this goal, concrete drill cores from a demolition site were systematically investigated by HSI in the short wave infrared field (1000-2500 nm). Results obtained by the adoption of the HSI approach showed as this technology can be successfully applied to analyze quality and characteristics of C&DW before dismantling and as final product to reutilise after demolition-milling-classification actions. The proposed technique and the related recognition logics, through the spectral signature detection of finite physical domains (i.e. concrete slice and/or particle) of different nature and composition, allows; i) to develop characterization procedures able to quantitatively assess end-of-life concrete compositional/textural characteristics and ii) to set up innovative sorting strategies to qualify the different materials constituting drill core samples.

The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers: Current Trends in Technology and Future Opportunities

PubMed Central

Breuer, Eun-Kyoung Yim; Murph, Mandi M.

2011-01-01

Technological and scientific innovations over the last decade have greatly contributed to improved diagnostics, predictive models, and prognosis among cancers affecting women. In fact, an explosion of information in these areas has almost assured future generations that outcomes in cancer will continue to improve. Herein we discuss the current status of breast, cervical, and ovarian cancers as it relates to screening, disease diagnosis, and treatment options. Among the differences in these cancers, it is striking that breast cancer has multiple predictive tests based upon tumor biomarkers and sophisticated, individualized options for prescription therapeutics while ovarian cancer lacks these tools. In addition, cervical cancer leads the way in innovative, cancer-preventative vaccines and multiple screening options to prevent disease progression. For each of these malignancies, emerging proteomic technologies based upon mass spectrometry, stable isotope labeling with amino acids, high-throughput ELISA, tissue or protein microarray techniques, and click chemistry in the pursuit of activity-based profiling can pioneer the next generation of discovery. We will discuss six of the latest techniques to understand proteomics in cancer and highlight research utilizing these techniques with the goal of improvement in the management of women's cancers. PMID:21886869

The MU-RAY experiment. An application of SiPM technology to the understanding of volcanic phenomena

NASA Astrophysics Data System (ADS)

Anastasio, A.; Ambrosino, F.; Basta, D.; Bonechi, L.; Brianzi, M.; Bross, A.; Callier, S.; Cassese, F.; Castellini, G.; Ciaranfi, R.; Cimmino, L.; D'Alessandro, R.; De Fazio, B.; de La Taille, C.; Garufi, F.; Iacobucci, G.; Martini, M.; Masone, V.; Mattone, C.; Miyamoto, S.; Montesi, M. C.; Nishiyama, R.; Noli, P.; Orazi, M.; Parascandolo, L.; Passeggio, G.; Peluso, R.; Pla-Dalmau, A.; Raux, L.; Rocco, R.; Rubinov, P.; Saracino, G.; Scarlini, E.; Scarpato, G.; Sekhniaidze, G.; Starodubtsev, O.; Strolin, P.; Taketa, A.; Tanaka, H. K. M.; Tanaka, M.; Uchida, T.

2013-08-01

The purpose of the MU-RAY project is to develop an innovative approach to the study of volcanoes and their monitoring based on a particle physics approach. The test site is Vesuvio: one of the higher risk volcanoes in the world. In this context, muon radiography is an innovative method of enormous impact. This is an imaging technique which relies on the measurement, by means of a cosmic ray telescope, of the absorption in the volcano of muons with near-horizontal trajectories, produced by the interactions of cosmic rays with the atmosphere. Since 2003 this technique has been successfully used on volcanoes in Japan, providing pictures of their vertices with resolutions much better than those obtained with the traditional techniques based on gravimeters. Researchers from Naples and Florence are currently involved in the construction and testing of a prototype telescope based on the use of bars of plastic scintillator with a triangular section whose scintillation light is collected by special fibres (wave length shifters) and transported to SiPM (Silicon photomultipliers). A complete prototype telescope, consisting of three xy scintillation planes and 1 m2 active area has been assembled and is now under test.

Treatment to Control Adhesion of Silicone-Based Elastomers

NASA Technical Reports Server (NTRS)

deGroh, Henry C., III; Puleo, Bernadette J.; Waters, Deborah L.

2013-01-01

Seals are used to facilitate the joining of two items, usually temporarily. At some point in the future, it is expected that the items will need to be separated. This innovation enables control of the adhesive properties of silicone-based elastomers. The innovation may also be effective on elastomers other than the silicone-based ones. A technique has been discovered that decreases the level of adhesion of silicone- based elastomers to negligible levels. The new technique causes less damage to the material compared to alternative adhesion mitigation techniques. Silicone-based elastomers are the only class of rubber-like materials that currently meet NASA s needs for various seal applications. However, silicone-based elastomers have natural inherent adhesive properties. This stickiness can be helpful, but it can frequently cause problems as well, such as when trying to get items apart. In the past, seal adhesion was not always adequately addressed, and has caused in-flight failures where seals were actually pulled from their grooves, preventing subsequent spacecraft docking until the seal was physically removed from the flange via an extravehicular activity (EVA). The primary method used in the past to lower elastomer seal adhesion has been the application of some type of lubricant or grease to the surface of the seal. A newer method uses ultraviolet (UV) radiation a mixture of UV wavelengths in the range of near ultraviolet (NUV) and vacuum ultraviolet (VUV) wavelengths.

An innovative middle tier design for protecting federal privacy act data

NASA Astrophysics Data System (ADS)

Allen, Thomas G. L.

2008-03-01

This paper identifies an innovative middle tier technique and design that provides a solid layer of network security for a single source of human resources (HR) data that falls under the Federal Privacy Act. The paper also discusses functionality for both retrieving data and updating data in a secure way. It will be shown that access to this information is limited by a security mechanism that authorizes all connections based on both application (client) and user information.

Ethics and surgical innovation: challenges to the professionalism of surgeons.

PubMed

Angelos, Peter

2013-01-01

The future of surgical progress depends on surgeons finding innovative solutions to their patients' problems. Surgical innovation is critical to advances in surgery. However, surgical innovation also raises a series of ethical issues that challenge the professionalism of surgeons. The very criteria for defining surgical progress have changed as patients may value more than simply reductions in morbidity and mortality. The requirement for informed consent prior to surgery is difficult when an innovative surgical procedure is planned since the risks of the novel operation may not be known. In addition, even if the risks are known in the hands of the innovator, the actual risks to patients when surgeons are learning the new technique are unknown. New techniques often depend on new technology which may be significantly more expensive than traditional techniques. There are no clear criteria to decide which new innovative techniques are going to turn out to be truly beneficial to patients. Many surgical innovations depend on new products which may have been developed as collaborative efforts between surgical device companies and surgeons. Although many currently accepted therapies were developed in this fashion, the collaboration of surgeons and device companies raises the potential for significant harmful conflicts of interest. In the decades to come, careful attention to these and other ethical issues will help to define the future professional standing of surgeons. Copyright © 2013 Elsevier Ltd and Surgical Associates Ltd. All rights reserved.

Surgical innovation and quality assurance: Can we have both?

PubMed

Georgeson, Keith

2015-06-01

Innovation is the major force for progress in pediatric surgery. Most of the progress in surgery has evolved secondary to novel approaches developed by surgeons confronted with difficult pathologic conditions. Up to the present time, most surgical innovation has been practiced with few rules for guidance. Innovation to make surgical procedures more effective and less morbid is highly desirable. However, the absence of oversight has the potential to lead to unbridled human experimentation. The quality improvement movement in medicine is attempting to improve outcomes using evidence-based clinical pathways. Quality improvement aims to decrease the variation in therapeutic approaches by scientifically defining best practices. There is a significant potential for autonomous surgical innovators to clash with well-meaning proponents of quality improvement. A suggested remedy to encourage surgical innovators while protecting patients from unintended harm is for institutions to develop Surgical Innovation Committees to evaluate and give oversight to the early application of new techniques and devices. Scientific evaluation under the auspices of an IRB should follow when feasible. Copyright © 2015 Elsevier Inc. All rights reserved.

Theoretical Bound of CRLB for Energy Efficient Technique of RSS-Based Factor Graph Geolocation

NASA Astrophysics Data System (ADS)

Kahar Aziz, Muhammad Reza; Heriansyah; Saputra, EfaMaydhona; Musa, Ardiansyah

2018-03-01

To support the increase of wireless geolocation development as the key of the technology in the future, this paper proposes theoretical bound derivation, i.e., Cramer Rao lower bound (CRLB) for energy efficient of received signal strength (RSS)-based factor graph wireless geolocation technique. The theoretical bound derivation is crucially important to evaluate whether the energy efficient technique of RSS-based factor graph wireless geolocation is effective as well as to open the opportunity to further innovation of the technique. The CRLB is derived in this paper by using the Fisher information matrix (FIM) of the main formula of the RSS-based factor graph geolocation technique, which is lied on the Jacobian matrix. The simulation result shows that the derived CRLB has the highest accuracy as a bound shown by its lowest root mean squared error (RMSE) curve compared to the RMSE curve of the RSS-based factor graph geolocation technique. Hence, the derived CRLB becomes the lower bound for the efficient technique of RSS-based factor graph wireless geolocation.

Using Zaltman Metaphor Elicitation Technique to Map Beneficiaries' Experiences and Values: A Case Example From the Sanitation Sector

ERIC Educational Resources Information Center

Kokko, Suvi; Lagerkvist, Carl Johan

2017-01-01

Using a case example of an innovative sanitation solution in a slum setting, this study explores the usefulness of the Zaltman Metaphor Elicitation Technique in a program planning and evaluation context. Using a qualitative image-based method to map people's mental models of ill-structured problems such as sanitation can aid program planners and…

Demonstration of innovative techniques for work zone safety data analysis

DOT National Transportation Integrated Search

2009-07-15

Based upon the results of the simulator data analysis, additional future research can be : identified to validate the driving simulator in terms of similarities with Ohio work zones. For : instance, the speeds observed in the simulator were greater f...

Innovative slide repair techniques guidebook for Missouri.

DOT National Transportation Integrated Search

2011-09-01

Soil slides often require immediate action to keep traffic moving safely. This study will : focus on developing newer (innovative) approaches to evaluate slope failures and : provide cost-effective repair and mitigation techniques. Typically slides a...

Updating Assessment Styles: Website Development Rather than Report Writing for Project Based Learning Courses

ERIC Educational Resources Information Center

Brown, Nicola

2017-01-01

While teaching methods tend to be updated frequently, the implementation of new innovative assessment tools is much slower. For example project based learning has become popular as a teaching technique, however, the assessment tends to be via traditional reports. This paper reports on the implementation and evaluation of using website development…

A Mobile-Based E-Learning System

ERIC Educational Resources Information Center

Ojokoh, Bolanle Adefowoke; Doyeni, Olubimtan Ayo; Adewale, Olumide Sunday; Isinkaye, Folasade Olubusola

2013-01-01

E-learning is an innovative approach for delivering electronically mediated, well-designed, learner-centred interactive learning environments by utilizing internet and digital technologies with respect to instructional design principles. This paper presents the application of Software Development techniques in the development of a Mobile Based…

Thomson Reuters innovation award research brief: the use of patent analytics in measuring innovation in India.

PubMed

Stembridge, Bob

2009-09-01

There are six different factors that can be used to assess the inventiveness of an organization and to determine how efficiently they apply invention resources to innovate effectively. This research briefing describes the techniques used to measure certain aspects of patenting activity by Small and Medium-sized Enterprises (SMEs) headquartered in India. The techniques are used to identify the most innovative SMEs in India in order to determine the winners of the Innovation Award 2009 from Thomson Reuters, awarded at InfoVision 2009 in Bangalore. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Statistical innovations in the medical device world sparked by the FDA.

PubMed

Campbell, Gregory; Yue, Lilly Q

2016-01-01

The world of medical devices while highly diverse is extremely innovative, and this facilitates the adoption of innovative statistical techniques. Statisticians in the Center for Devices and Radiological Health (CDRH) at the Food and Drug Administration (FDA) have provided leadership in implementing statistical innovations. The innovations discussed include: the incorporation of Bayesian methods in clinical trials, adaptive designs, the use and development of propensity score methodology in the design and analysis of non-randomized observational studies, the use of tipping-point analysis for missing data, techniques for diagnostic test evaluation, bridging studies for companion diagnostic tests, quantitative benefit-risk decisions, and patient preference studies.

MERINOVA: Meteorological risks as drivers of environmental innovation in agro-ecosystem management

NASA Astrophysics Data System (ADS)

Gobin, Anne; Oger, Robert; Marlier, Catherine; Van De Vijver, Hans; Vandermeulen, Valerie; Van Huylenbroeck, Guido; Zamani, Sepideh; Curnel, Yannick; Mettepenningen, Evi

2013-04-01

The BELSPO funded project 'MERINOVA' deals with risks associated with extreme weather phenomena and with risks of biological origin such as pests and diseases. The major objectives of the proposed project are to characterise extreme meteorological events, assess the impact on Belgian agro-ecosystems, characterise their vulnerability and resilience to these events, and explore innovative adaptation options to agricultural risk management. The project comprises of five major parts that reflect the chain of risks: (i) Hazard: Assessing the likely frequency and magnitude of extreme meteorological events by means of probability density functions; (ii) Impact: Analysing the potential bio-physical and socio-economic impact of extreme weather events on agro-ecosystems in Belgium using process-based modelling techniques commensurate with the regional scale; (iii) Vulnerability: Identifying the most vulnerable agro-ecosystems using fuzzy multi-criteria and spatial analysis; (iv) Risk Management: Uncovering innovative risk management and adaptation options using actor-network theory and fuzzy cognitive mapping techniques; and, (v) Communication: Communicating to research, policy and practitioner communities using web-based techniques. The different tasks of the MERINOVA project require expertise in several scientific disciplines: meteorology, statistics, spatial database management, agronomy, bio-physical impact modelling, socio-economic modelling, actor-network theory, fuzzy cognitive mapping techniques. These expertises are shared by the four scientific partners who each lead one work package. The MERINOVA project will concentrate on promoting a robust and flexible framework by demonstrating its performance across Belgian agro-ecosystems, and by ensuring its relevance to policy makers and practitioners. Impacts developed from physically based models will not only provide information on the state of the damage at any given time, but also assist in understanding the links between different factors causing damage and determining bio-physical vulnerability. Socio-economic impacts will enlarge the basis for vulnerability mapping, risk management and adaptation options. A strong expert and end-user network will be established to help disseminating and exploiting project results to meet user needs.

Towards automating the discovery of certain innovative design principles through a clustering-based optimization technique

NASA Astrophysics Data System (ADS)

Bandaru, Sunith; Deb, Kalyanmoy

2011-09-01

In this article, a methodology is proposed for automatically extracting innovative design principles which make a system or process (subject to conflicting objectives) optimal using its Pareto-optimal dataset. Such 'higher knowledge' would not only help designers to execute the system better, but also enable them to predict how changes in one variable would affect other variables if the system has to retain its optimal behaviour. This in turn would help solve other similar systems with different parameter settings easily without the need to perform a fresh optimization task. The proposed methodology uses a clustering-based optimization technique and is capable of discovering hidden functional relationships between the variables, objective and constraint functions and any other function that the designer wishes to include as a 'basis function'. A number of engineering design problems are considered for which the mathematical structure of these explicit relationships exists and has been revealed by a previous study. A comparison with the multivariate adaptive regression splines (MARS) approach reveals the practicality of the proposed approach due to its ability to find meaningful design principles. The success of this procedure for automated innovization is highly encouraging and indicates its suitability for further development in tackling more complex design scenarios.

Evaluating the enhancement and improvement of China's technology and financial services platform innovation strategy.

PubMed

Wu, Ching-Sung; Hu, Kuang-Hua; Chen, Fu-Hsiang

2016-01-01

The development of high-tech industry has been prosperous around the world in past decades, while technology and finance have already become the most significant issues in the information era. While high-tech firms are a major force behind a country's economic development, it requires a lot of money for the development process, as well as the financing difficulties for its potential problems, thus, how to evaluate and establish appropriate technology and financial services platforms innovation strategy has become one of the most critical and difficult issues. Moreover, how the chosen intertwined financial environment can be optimized in order that high-tech firms financing problems can be decided has seldom been addressed. Thus, this research aims to establish a technology and financial services platform innovation strategy improvement model, as based on the hybrid MADM model, which addresses the main causal factors and amended priorities in order to strengthen ongoing planning. A DEMATEL technique, as based on Analytic Network Process, as well as modified VIKOR, will be proposed for selecting and re-configuring the aspired technology and financial services platform. An empirical study, as based on China's technology and financial services platform innovation strategy, will be provided for verifying the effectiveness of this proposed methodology. Based on expert interviews, technology and financial services platforms innovation strategy improvement should be made in the following order: credit guarantee platform ( C )_credit rating platform ( B )_investment and finance platform ( A ).

SCIENCE RESULTS INTEGRATION. BRINGING MOLECULAR BIOLOGY TECHNIQUES TO REGIONAL WATER MONITORING PROGRAMS

EPA Science Inventory

EPA's Office of Research and Development (ORD) develops innovative methods for use in environmental monitoring and assessment by scientists in Regions, states, and Tribes. Molecular-biology-based methods are not yet established in the environmental monitoring "tool box". SRI (Sci...

A technique for measuring vertically and horizontally polarized microwave brightness temperatures using electronic polarization-basis rotation

NASA Technical Reports Server (NTRS)

Gasiewski, Albin J.

1992-01-01

This technique for electronically rotating the polarization basis of an orthogonal-linear polarization radiometer is based on the measurement of the first three feedhorn Stokes parameters, along with the subsequent transformation of this measured Stokes vector into a rotated coordinate frame. The technique requires an accurate measurement of the cross-correlation between the two orthogonal feedhorn modes, for which an innovative polarized calibration load was developed. The experimental portion of this investigation consisted of a proof of concept demonstration of the technique of electronic polarization basis rotation (EPBR) using a ground based 90-GHz dual orthogonal-linear polarization radiometer. Practical calibration algorithms for ground-, aircraft-, and space-based instruments were identified and tested. The theoretical effort consisted of radiative transfer modeling using the planar-stratified numerical model described in Gasiewski and Staelin (1990).

Knowledge Management Orientation: An Innovative Perspective to Hospital Management.

PubMed

Ghasemi, Matina; Ghadiri Nejad, Mazyar; Bagzibagli, Kemal

2017-12-01

By considering innovation as a new project in hospitals, all the project management's standard steps should be followed in execution. This study investigated the validation of a new set of measures in terms of providing a procedure for knowledge management-oriented innovation that enriches the hospital management system. The relation between innovation and all the knowledge management areas, as the main constructs of project management, was illustrated by referring to project management standard steps and previous studies. Through consultations and meetings with a committee of professional project managers, a questionnaire was developed to measure ten knowledge management areas in hospital's innovation process. Additionally, a group of experts from hospital managers were invited to comment on the applicability of the questionnaires by considering if the items are measurable in hospitals practically. A close-ended, Likert-type scale items, consisted of ten sections, were developed based on project management body of knowledge thorough Delphi technique. It enables the managers to evaluate hospitals' situation to be aware whether the organization follows the knowledge management standards in innovation process or not. By pilot study, confirmatory factor analysis and exploratory factor analysis were conducted to ensure the validity and reliability of the measurement items. The developed items seem to have a potential to help hospital managers and subsequently delivering new products/services successfully based on the standard procedures in their organization. In all innovation processes, the knowledge management areas and their standard steps help hospital managers by a new tool as questionnaire format.

Electrical characterization of a Mapham inverter using pulse testing techniques

NASA Technical Reports Server (NTRS)

Baumann, E. D.; Myers, I. T.; Hammoud, A. N.

1990-01-01

The use of a multiple pulse testing technique to determine the electrical characteristics of large megawatt-level power systems for aerospace missions is proposed. An innovative test method based on the multiple pulse technique is demonstrated on a 2-kW Mapham inverter. The concept of this technique shows that characterization of large power systems under electrical equilibrium at rated power can be accomplished without large costly power supplies. The heat generation that occurs in systems when tested in a continuous mode is eliminated. The results indicate that there is a good agreement between this testing technique and that of steady state testing.

Cartilage-Repair Innovation at a Standstill: Methodologic and Regulatory Pathways to Breaking Free.

PubMed

Lyman, Stephen; Nakamura, Norimasa; Cole, Brian J; Erggelet, Christoph; Gomoll, Andreas H; Farr, Jack

2016-08-03

Articular cartilage defects strongly predispose patients to developing early joint degeneration and osteoarthritis, but for more than 15 years, no new cartilage-repair technologies that we know of have been approved by the U.S. Food and Drug Administration. Many studies examining novel approaches to cartilage repair, including cell, tissue, or matrix-based techniques, have shown great promise, but completing randomized controlled trials (RCTs) to establish safety and efficacy has been challenging, providing a major barrier to bringing these innovations into clinical use. In this article, we review reasons that surgical innovations are not well-suited for testing through RCTs. We also discuss how analytical methods for reducing bias, such as propensity scoring, make prospective observational studies a potentially viable alternative for testing the safety and efficacy of cartilage-repair and other novel therapies, offering the real possibility of therapeutic innovation. Copyright © 2016 by The Journal of Bone and Joint Surgery, Incorporated.

Six Thinking Hats and Social Workers' Innovative Competence: An Experimental Study

ERIC Educational Resources Information Center

Azeez, Razaq Olugbenga

2016-01-01

Employees, no doubt, are the main force in organizations, and their innovative behaviours are vital for outcome efficacy. Innovative organisations, therefore, need creative employees who generate new ideas for product or process of innovation. This study investigated the effect of six thinking hats creativity technique on innovative competence of…

Brainstorming for breakthrough thinking.

PubMed

Shirey, Maria R

2011-12-01

This department highlights change management strategies that may be used in strategically planning and executing organizational change initiatives. With the goal of presenting practical approaches helpful to nurse leaders advancing organizational change, content includes evidence-based projects, tools, and resources that mobilize and sustain organizational change initiatives. In this article, the author discusses brainstorming as a viable innovation technique and goal-based change intervention.

Electronic Creativity Techniques for Organizational Innovation.

ERIC Educational Resources Information Center

Siau, Keng L.

1996-01-01

Discusses using advanced electronic and communication technology to improve organizational innovation. Group creativity techniques, such as electronic brainstorming, PMI (a brainstorming approach involving plus, minus, and interesting points), synectics, and their verbal counterparts are compared. Electronic PMI and synectics are found to be…

Reviewing effectiveness of ankle assessment techniques for use in robot-assisted therapy.

PubMed

Zhang, Mingming; Davies, T Claire; Zhang, Yanxin; Xie, Shane

2014-01-01

This article provides a comprehensive review of studies that investigated ankle assessment techniques to better understand those that can be used in the real-time monitoring of rehabilitation progress for implementation in conjunction with robot-assisted therapy. Seventy-six publications published between January 1980 and August 2013 were selected based on eight databases. They were divided into two main categories (16 qualitative and 60 quantitative studies): 13 goniometer studies, 18 dynamometer studies, and 29 studies about innovative techniques. A total of 465 subjects participated in the 29 quantitative studies of innovative measurement techniques that may potentially be integrated in a real-time monitoring device, of which 19 studies included less than 10 participants. Results show that qualitative ankle assessment methods are not suitable for real-time monitoring in robot-assisted therapy, though they are reliable for certain patients, while the quantitative methods show great potential. The majority of quantitative techniques are reliable in measuring ankle kinematics and kinetics but are usually available only for use in the sagittal plane. Limited studies determine kinematics and kinetics in all three planes (sagittal, transverse, and frontal) where motions of the ankle joint and the subtalar joint actually occur.

Ontogeny of a surgical technique: Robotic kidney transplantation with regional hypothermia.

PubMed

Sood, Akshay; McCulloch, Peter; Dahm, Philipp; Ahlawat, Rajesh; Jeong, Wooju; Bhandari, Mahendra; Menon, Mani

2016-01-01

Innovation is a hallmark of surgical practice. It is generally accepted that a new procedure will undergo technical changes during its evolution; however, quantitative accounts of the process are limited. Multiple groups, including our own, have recently described a minimally-invasive approach to conventional kidney transplantation (KT) operation. Unique to our experience is a structured development of the technique within the confines of a safe surgical innovation framework - the IDEAL framework (idea, development, exploration, assessment, long-term monitoring; stages 0-4). We here provide a first-hand narrative of the progress of robotic KT operation from preclinical trial to clinical application. Overall, 54 patients underwent robotic KT with regional hypothermia successfully. Major technical changes including selection of optimal patient position (flank vs. lithotomy), robotic instrumentation, vascular occlusion method (bulldog vs. tourniquet) and suture material (prolene vs. GoreTex) occurred early during the procedure development (IDEAL stage 0, preclinical). Minor technical changes such as utilization of the aortic punch for arteriotomy (case 3), use of barbed suture during ureteroneocystostomy (case 6) and extraperitonealization of the graft kidney (case 6) that increased the efficiency and safety of the procedure continued throughout procedure development (IDEAL stages 1-2, clinical stages). We demonstrate that a surgical technique evolves continually; although, the majority of technical alterations occur early in the life-cycle of the procedure. Development of a new technique within the confines a structured surgical innovation framework allows for evidence based progression of the technique and may minimize the risk of harm to the patient. Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

[The future of radiology: What can we expect within the next 10 years?].

PubMed

Nensa, F; Forsting, M; Wetter, A

2016-03-01

More than other medical discipline, radiology is marked by technical innovation and continuous development, as well as the optimization of the underlying physical principles. In this respect, several trends that will crucially change and develop radiology over the next decade can be observed. Through the use of ever faster computer tomography, which also shows an ever-decreasing radiation exposure, the "workhorse" of radiology will have an even greater place and displace conventional X‑ray techniques further. In addition, hybrid imaging, which is based on a combination of nuclear medicine and radiological techniques (keywords: PET/CT, PET/MRI) will become much more established and, in particular, will improve oncological imaging further, allowing increasingly individualized imaging for specific tracers and techniques of functional magnetic resonance imaging for a particular tumour. Future radiology will be strongly characterized by innovations in the software and Internet industry, which will enable new image viewing and processing methods and open up new possibilities in the context of the organization of radiological work.

Valuing innovative endoscopic techniques: per-oral endoscopic myotomy for the management of achalasia.

PubMed

Shah, Eric D; Chang, Andrew C; Law, Ryan

2018-04-20

Unclear reimbursement for new and innovative endoscopic procedures can limit adoption in clinical practice despite effectiveness in clinical trials. The aim of this study was to determine maximum cost-effective reimbursement for per-oral endoscopic myotomy (POEM) in treating achalasia. We constructed a decision analytic model assessing POEM versus laparoscopic Heller myotomy with Dor fundoplication (LHM) in managing achalasia from a payer perspective over a 1-year time horizon. Reimbursement data were derived from 2017 Medicare data. Responder rates were based on clinically meaningful improvement in validated Eckardt scores. Validated health utility values were assigned to terminal health states based on data previously derived with a standard gamble technique. Contemporary willingness-to-pay (WTP) levels per quality-adjusted life year (QALY) were used to estimate maximum reimbursement for POEM using threshold analysis. Effectiveness of POEM and LHM was similar at one year of follow-up (0.91 QALY). Maximum cost-effective reimbursement for POEM was $1,200.07 to $1,389.85 (33.4-38.7 total 2017 RVUs). This compares to contemporary total reimbursement of 10-15 total RVU for advanced endoscopic procedures. The model was most sensitive to the probability of GERD after procedure. The rate of conversion to open laparotomy due to perforation or bleeding was infrequent in published clinical practice experience, thus did not significantly affect reimbursement. POEM is an example of an innovative and potentially disruptive endoscopic technique offering greater cost-effective value and similar outcomes to the established surgical standard at contemporary reimbursement levels. Copyright © 2018 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

77 FR 18793 - Spectrum Sharing Innovation Test-Bed Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

.... 120322212-2212-01] Spectrum Sharing Innovation Test-Bed Pilot Program AGENCY: National Telecommunications... Innovation Test-Bed pilot program to assess whether devices employing Dynamic Spectrum Access techniques can... Spectrum Sharing Innovation Test-Bed (Test-Bed) pilot program to examine the feasibility of increased...

Advanced Visualization and Interactive Display Rapid Innovation and Discovery Evaluation Research (VISRIDER) Program Task 6: Point Cloud Visualization Techniques for Desktop and Web Platforms

DTIC Science & Technology

2017-04-01

ADVANCED VISUALIZATION AND INTERACTIVE DISPLAY RAPID INNOVATION AND DISCOVERY EVALUATION RESEARCH (VISRIDER) PROGRAM TASK 6: POINT CLOUD...To) OCT 2013 – SEP 2014 4. TITLE AND SUBTITLE ADVANCED VISUALIZATION AND INTERACTIVE DISPLAY RAPID INNOVATION AND DISCOVERY EVALUATION RESEARCH...various point cloud visualization techniques for viewing large scale LiDAR datasets. Evaluate their potential use for thick client desktop platforms

New Challenges in Tribology: Wear Assessment Using 3D Optical Scanners

PubMed Central

Valigi, Maria Cristina; Logozzo, Silvia; Affatato, Saverio

2017-01-01

Wear is a significant mechanical and clinical problem. To acquire further knowledge on the tribological phenomena that involve freeform mechanical components or medical prostheses, wear tests are performed on biomedical and industrial materials in order to solve or reduce failures or malfunctions due to material loss. Scientific and technological advances in the field of optical scanning allow the application of innovative devices for wear measurements, leading to improvements that were unimaginable until a few years ago. It is therefore important to develop techniques, based on new instrumentations, for more accurate and reproducible measurements of wear. The aim of this work is to discuss the use of innovative 3D optical scanners and an experimental procedure to detect and evaluate wear, comparing this technique with other wear evaluation methods for industrial components and biomedical devices. PMID:28772905

New Challenges in Tribology: Wear Assessment Using 3D Optical Scanners.

PubMed

Valigi, Maria Cristina; Logozzo, Silvia; Affatato, Saverio

2017-05-18

Wear is a significant mechanical and clinical problem. To acquire further knowledge on the tribological phenomena that involve freeform mechanical components or medical prostheses, wear tests are performed on biomedical and industrial materials in order to solve or reduce failures or malfunctions due to material loss. Scientific and technological advances in the field of optical scanning allow the application of innovative devices for wear measurements, leading to improvements that were unimaginable until a few years ago. It is therefore important to develop techniques, based on new instrumentations, for more accurate and reproducible measurements of wear. The aim of this work is to discuss the use of innovative 3D optical scanners and an experimental procedure to detect and evaluate wear, comparing this technique with other wear evaluation methods for industrial components and biomedical devices.

Innovation Abstracts, Volume IV, Numbers 1-36.

ERIC Educational Resources Information Center

Watkins, Karen, Ed.

1982-01-01

Brief, two-page abstracts are provided on 36 educational topics of interest to community college faculty, administrators, and staff. The topics covered are: (1) a student retention technique; (2) educational productivity and quality; (3) competency-based adult education; (4) part-time faculty; (5) Beaver College's (Pennsylvania) writing across the…

The "Iron Inventor": Using Creative Problem Solving to Spur Student Creativity

ERIC Educational Resources Information Center

Lee, Seung Hwan; Hoffman, K. Douglas

2014-01-01

Based on the popular television show the "Iron Chef," an innovative marketing activity called the "Iron Inventor" is introduced. Using the creative problem-solving approach and active learning techniques, the Iron Inventor facilitates student learning pertaining to the step-by-step processes of creating a new product and…

Lewin's Impact on Education: Instilling Cooperation and Conflict Management Skills in School Children.

ERIC Educational Resources Information Center

Maruyama, Geoffrey

1992-01-01

A Lewinian orientation to educational problems fits current innovative thinking in education (e.g., models for making education multicultural), and provides the bases of important applied work on cooperative learning techniques and constructive ways of structuring conflict within educational settings. Lewinian field theory provides a broad…

ALES: An Innovative Argument-Learning Environment

ERIC Educational Resources Information Center

Abbas, Safia; Sawamura, Hajime

2010-01-01

This paper presents the development of an Argument-Learning System (ALES). The idea is based on the AIF (argumentation interchange format) ontology using "Walton theory". ALES uses different mining techniques to manage a highly structured arguments repository. This repository was designed, developed and implemented by the authors. The aim is to…

Predicting the Emplacement of Improvised Explosive Devices: An Innovative Solution

ERIC Educational Resources Information Center

Lerner, Warren D.

2013-01-01

In this quantitative correlational study, simulated data were employed to examine artificial-intelligence techniques or, more specifically, artificial neural networks, as they relate to the location prediction of improvised explosive devices (IEDs). An ANN model was developed to predict IED placement, based upon terrain features and objects…

36 CFR 72.42 - Expansion and new development.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Rehabilitation and Innovation § 72.42 Expansion and new development. (a) Expansion. Because the UPARR Program is... development will not be assisted under a rehabilitation grant. (2) Innovation. New development may be allowed under an Innovation grant when it is directly related to a specific innovative idea or technique...

36 CFR 72.42 - Expansion and new development.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Rehabilitation and Innovation § 72.42 Expansion and new development. (a) Expansion. Because the UPARR Program is... development will not be assisted under a rehabilitation grant. (2) Innovation. New development may be allowed under an Innovation grant when it is directly related to a specific innovative idea or technique...

36 CFR 72.42 - Expansion and new development.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Rehabilitation and Innovation § 72.42 Expansion and new development. (a) Expansion. Because the UPARR Program is... development will not be assisted under a rehabilitation grant. (2) Innovation. New development may be allowed under an Innovation grant when it is directly related to a specific innovative idea or technique...

36 CFR 72.42 - Expansion and new development.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Rehabilitation and Innovation § 72.42 Expansion and new development. (a) Expansion. Because the UPARR Program is... development will not be assisted under a rehabilitation grant. (2) Innovation. New development may be allowed under an Innovation grant when it is directly related to a specific innovative idea or technique...

A Hybrid Optimization Framework with POD-based Order Reduction and Design-Space Evolution Scheme

NASA Astrophysics Data System (ADS)

Ghoman, Satyajit S.

The main objective of this research is to develop an innovative multi-fidelity multi-disciplinary design, analysis and optimization suite that integrates certain solution generation codes and newly developed innovative tools to improve the overall optimization process. The research performed herein is divided into two parts: (1) the development of an MDAO framework by integration of variable fidelity physics-based computational codes, and (2) enhancements to such a framework by incorporating innovative features extending its robustness. The first part of this dissertation describes the development of a conceptual Multi-Fidelity Multi-Strategy and Multi-Disciplinary Design Optimization Environment (M3 DOE), in context of aircraft wing optimization. M 3 DOE provides the user a capability to optimize configurations with a choice of (i) the level of fidelity desired, (ii) the use of a single-step or multi-step optimization strategy, and (iii) combination of a series of structural and aerodynamic analyses. The modularity of M3 DOE allows it to be a part of other inclusive optimization frameworks. The M 3 DOE is demonstrated within the context of shape and sizing optimization of the wing of a Generic Business Jet aircraft. Two different optimization objectives, viz. dry weight minimization, and cruise range maximization are studied by conducting one low-fidelity and two high-fidelity optimization runs to demonstrate the application scope of M3 DOE. The second part of this dissertation describes the development of an innovative hybrid optimization framework that extends the robustness of M 3 DOE by employing a proper orthogonal decomposition-based design-space order reduction scheme combined with the evolutionary algorithm technique. The POD method of extracting dominant modes from an ensemble of candidate configurations is used for the design-space order reduction. The snapshot of candidate population is updated iteratively using evolutionary algorithm technique of fitness-driven retention. This strategy capitalizes on the advantages of evolutionary algorithm as well as POD-based reduced order modeling, while overcoming the shortcomings inherent with these techniques. When linked with M3 DOE, this strategy offers a computationally efficient methodology for problems with high level of complexity and a challenging design-space. This newly developed framework is demonstrated for its robustness on a nonconventional supersonic tailless air vehicle wing shape optimization problem.

Knowledge Management Orientation: An Innovative Perspective to Hospital Management

PubMed Central

GHASEMI, Matina; GHADIRI NEJAD, Mazyar; BAGZIBAGLI, Kemal

2017-01-01

Background: By considering innovation as a new project in hospitals, all the project management’s standard steps should be followed in execution. This study investigated the validation of a new set of measures in terms of providing a procedure for knowledge management-oriented innovation that enriches the hospital management system. Methods: The relation between innovation and all the knowledge management areas, as the main constructs of project management, was illustrated by referring to project management standard steps and previous studies. Through consultations and meetings with a committee of professional project managers, a questionnaire was developed to measure ten knowledge management areas in hospital’s innovation process. Additionally, a group of experts from hospital managers were invited to comment on the applicability of the questionnaires by considering if the items are measurable in hospitals practically. Results: A close-ended, Likert-type scale items, consisted of ten sections, were developed based on project management body of knowledge thorough Delphi technique. It enables the managers to evaluate hospitals’ situation to be aware whether the organization follows the knowledge management standards in innovation process or not. By pilot study, confirmatory factor analysis and exploratory factor analysis were conducted to ensure the validity and reliability of the measurement items. Conclusion: The developed items seem to have a potential to help hospital managers and subsequently delivering new products/services successfully based on the standard procedures in their organization. In all innovation processes, the knowledge management areas and their standard steps help hospital managers by a new tool as questionnaire format. PMID:29259938

Coevolution in management fashion: an agent-based model of consultant-driven innovation.

PubMed

Strang, David; David, Robert J; Akhlaghpour, Saeed

2014-07-01

The rise of management consultancy has been accompanied by increasingly marked faddish cycles in management techniques, but the mechanisms that underlie this relationship are not well understood. The authors develop a simple agent-based framework that models innovation adoption and abandonment on both the supply and demand sides. In opposition to conceptions of consultants as rhetorical wizards who engineer waves of management fashion, firms and consultants are treated as boundedly rational actors who chase the secrets of success by mimicking their highest-performing peers. Computational experiments demonstrate that consultant-driven versions of this dynamic in which the outcomes of firms are strongly conditioned by their choice of consultant are robustly faddish. The invasion of boom markets by low-quality consultants undercuts popular innovations while simultaneously restarting the fashion cycle by prompting the flight of high-quality consultants into less densely occupied niches. Computational experiments also indicate conditions involving consultant mobility, aspiration levels, mimic probabilities, and client-provider matching that attenuate faddishness.

Robust detection, isolation and accommodation for sensor failures

NASA Technical Reports Server (NTRS)

Emami-Naeini, A.; Akhter, M. M.; Rock, S. M.

1986-01-01

The objective is to extend the recent advances in robust control system design of multivariable systems to sensor failure detection, isolation, and accommodation (DIA), and estimator design. This effort provides analysis tools to quantify the trade-off between performance robustness and DIA sensitivity, which are to be used to achieve higher levels of performance robustness for given levels of DIA sensitivity. An innovations-based DIA scheme is used. Estimators, which depend upon a model of the process and process inputs and outputs, are used to generate these innovations. Thresholds used to determine failure detection are computed based on bounds on modeling errors, noise properties, and the class of failures. The applicability of the newly developed tools are demonstrated on a multivariable aircraft turbojet engine example. A new concept call the threshold selector was developed. It represents a significant and innovative tool for the analysis and synthesis of DiA algorithms. The estimators were made robust by introduction of an internal model and by frequency shaping. The internal mode provides asymptotically unbiased filter estimates.The incorporation of frequency shaping of the Linear Quadratic Gaussian cost functional modifies the estimator design to make it suitable for sensor failure DIA. The results are compared with previous studies which used thresholds that were selcted empirically. Comparison of these two techniques on a nonlinear dynamic engine simulation shows improved performance of the new method compared to previous techniques

NASA's Public Participation Universe: Why and How the U.S. Space Agency Is Democratizing Its Approaches to Innovation

NASA Technical Reports Server (NTRS)

Kaminski, Amy; Buquo, Lynn; Roman, Monsi; Beck, Beth; Thaller, Michelle

2016-01-01

This paper analyzes NASA's increasing effort to invite greater public participation in its techno scientific work through open innovation methodologies. First we examine why NASA has expanded its use of these approaches, noting the roles of an intertwined set of forcing functions including budget constraints, the availability of technological resources, and committed individuals. Next we outline the strategies the agency has invoked to engage the public in research, technology development, and other activities to advance and shape NASA's mission. As we show, promoting greater public involvement has entailed facilitating the NASA workforce's familiarity with open innovation approaches as well as developing projects and creating outreach strategies appropriate to the envisioned participant base. We then discuss the wide variety of outcomes NASA's open innovation initiatives have yielded in support of NASA research and development objectives as well as benefits to participants and others. We conclude with a discussion of the remaining barriers to the use of open innovation techniques as a standard practice and the strategies in work to overcome those barriers so the full potential of a democratized approach to innovation can be realized.

'They hear "Africa" and they think that there can't be any good services'--perceived context in cross-national learning: a qualitative study of the barriers to Reverse Innovation.

PubMed

Harris, Matthew; Weisberger, Emily; Silver, Diana; Macinko, James

2015-11-19

Country-of-origin of a product can negatively influence its rating, particularly if the product is from a low-income country. It follows that how non-traditional sources of innovation, such as low-income countries, are perceived is likely to be an important part of a diffusion process, particularly given the strong social and cognitive boundaries associated with the healthcare professions. Between September and December 2014, we conducted eleven in-depth face-to-face or telephone interviews with key informants from innovation, health and social policy circles, experts in international comparative policy research and leaders in Reverse Innovation in the United States. Interviews were open-ended with guiding probes into the barriers and enablers to Reverse Innovation in the US context, specifically also to understand whether, in their experience translating or attempting to translate innovations from low-income contexts into the US, the source of the innovation matters in the adopter context. Interviews were recorded, transcribed and analyzed thematically using the process of constant comparison. Our findings show that innovations from low-income countries tend to be discounted early on because of prior assumptions about the potential for these contexts to offer solutions to healthcare problems in the US. Judgments are made about the similarity of low-income contexts with the US, even though this is based oftentimes on flimsy perceptions only. Mixing levels of analysis, local and national, leads to country-level stereotyping and missed opportunities to learn from low-income countries. Our research highlights that prior expectations, invoked by the Low-income country cue, are interfering with a transparent and objective learning process. There may be merit in adopting some techniques from the cognitive psychology and marketing literatures to understand better the relative importance of source in healthcare research and innovation diffusion. Counter-stereotyping techniques and decision-making tools may be useful to help decision-makers evaluate the generalizability of research findings objectively and transparently. We suggest that those interested in Reverse Innovation should reflect carefully on the value of disclosing the source of the innovation that is being proposed, if doing so is likely to invoke negative stereotypes.

Innovative single-shot diagnostics for electrons accelerated through laser-plasma interaction at FLAME

NASA Astrophysics Data System (ADS)

Bisesto, F. G.; Anania, M. P.; Chiadroni, E.; Cianchi, A.; Costa, G.; Curcio, A.; Ferrario, M.; Galletti, M.; Pompili, R.; Schleifer, E.; Zigler, A.

2017-05-01

Plasma wakefield acceleration is the most promising acceleration technique known nowadays, able to provide very high accelerating fields (> 100 GV/m), enabling acceleration of electrons to GeV energy in few centimeters. Here we present all the plasma related activities currently underway at SPARC LAB exploiting the high power laser FLAME. In particular, we will give an overview of the single shot diagnostics employed: Electro Optic Sampling (EOS) for temporal measurement and optical transition radiation (OTR) for an innovative one shot emittance measurements. In detail, the EOS technique has been employed to measure for the first time the longitudinal profile of electric field of fast electrons escaping from a solid target, driving the ions and protons acceleration, and to study the impact of using different target shapes. Moreover, a novel scheme for one shot emittance measurements based on OTR, developed and tested at SPARC LAB LINAC, will be shown.

Microseismic techniques for avoiding induced seismicity during fluid injection

DOE PAGES

Matzel, Eric; White, Joshua; Templeton, Dennise; ...

2014-01-01

The goal of this research is to develop a fundamentally better approach to geological site characterization and early hazard detection. We combine innovative techniques for analyzing microseismic data with a physics-based inversion model to forecast microseismic cloud evolution. The key challenge is that faults at risk of slipping are often too small to detect during the site characterization phase. Our objective is to devise fast-running methodologies that will allow field operators to respond quickly to changing subsurface conditions.

Cotton Island: Students' Learning Motivation Using a Virtual World

ERIC Educational Resources Information Center

Wyss, Jamie; Lee, Seung-Eun; Domina, Tanya; MacGillivray, Maureen

2014-01-01

As technology advances, it is important for teachers to seamlessly integrate technology into their innovative teaching techniques. Using virtual worlds is one alternative to traditional teaching methods that can provide rich learning experiences. The purpose of this article is twofold: (a) to present Cotton Island, an avatar-based 3-D virtual…

Innovative Problems of Improving the Quality of Life of the Welfare State

ERIC Educational Resources Information Center

Panachev, Valery D.

2016-01-01

Improvement of the population quality of life should be based on promoting healthy lifestyle, active physical exercises and sports activities as one of its main priorities. In order to facilitate the achievement of this priority, the author proposes management technique of complicated coordination movements in space in the development of…

I/MLEs and the Uneven Return of Pastoral Power

ERIC Educational Resources Information Center

Bojesen, Emile

2017-01-01

Informed by the work of the work of Michel Foucault, Ian Hunter, and Ansgar Allen, this paper argues that I/MLEs are not the creation of a "modern" or "innovative" learning environment but rather the reclamation of an educational technique that was pioneered en masse almost two centuries ago (and based on practices many…

Ionic liquids in solid-phase microextraction: a review.

PubMed

Ho, Tien D; Canestraro, Anthony J; Anderson, Jared L

2011-06-10

Solid-phase microextraction (SPME) has undergone a surge in popularity within the field of analytical chemistry in the past two decades since its introduction. Owing to its nature of extraction, SPME has become widely known as a quick and cost-effective sample preparation technique. Although SPME has demonstrated extraordinary versatility in sampling capabilities, the technique continues to experience a tremendous growth in innovation. Presently, increasing efforts have been directed towards the engineering of novel sorbent material in order to expand the applicability of SPME for a wider range of analytes and matrices. This review highlights the application of ionic liquids (ILs) and polymeric ionic liquids (PILs) as innovative sorbent materials for SPME. Characterized by their unique physico-chemical properties, these compounds can be structurally-designed to selectively extract target analytes based on unique molecular interactions. To examine the advantages of IL and PIL-based sorbent coatings in SPME, the field is reviewed by gathering available experimental data and exploring the sensitivity, linear calibration range, as well as detection limits for a variety of target analytes in the methods that have been developed. Copyright © 2011 Elsevier B.V. All rights reserved.

Institutional Review Board approval and innovation in urology: current practice and safety issues.

PubMed

Sundaram, Varun; Vemana, Goutham; Bhayani, Sam B

2014-02-01

To retrospectively review recent publications describing novel procedures/techniques, and describe the Institutional Review Board (IRB)/ethics approval process and potential ethical dilemmas in their reporting. We searched PubMed for papers about innovative or novel procedures/techniques between 2011 and August 2012. A query of titles/abstracts in the Journal of Urology, Journal of Endourology, European Urology, BJU International, and Urology identified relevant papers. These results were reviewed for human studies that described an innovative technique, procedure, approach, initial series, and/or used new technology. In all, 91 papers met criteria for inclusion; 25 from the Journal of Endourology, 14 from the Journal of Urology, nine from European Urology, 15 from the BJU International and 28 from Urology. IRB/ethics approval was given for an experimental procedure or database in 24% and 22%, respectively. IRB/ethics approval was not mentioned in 52.7% of studies. Published IRB/ethics approvals for innovative techniques are heterogeneous including database, retrospective, and prospective approvals. Given the concept that innovations are likely not in the legal or ethical standard of care, strong consideration should be given to obtaining IRB/ethics approval before the actual procedure, instead of approval to merely report database outcomes. © 2013 The Authors. BJU International © 2013 BJU International.

Comparison of Traditional and Innovative Techniques to Solve Technical Challenges

NASA Technical Reports Server (NTRS)

Perchonok, Michele

2011-01-01

This slide presentation reviews the use of traditional and innovative techniques to solve technical challenges in food storage technology. The planning for a mission to Mars is underway, and the food storage technology improvements requires that improvements be made. This new technology is required, because current food storage technology is inadequate,refrigerators or freezers are not available for food preservation, and that a shelf life of 5 years is expected. A 10 year effort to improve food packaging technology has not enhanced significantly food packaging capabilities. Two innovation techniques were attempted InnoCentive and Yet2.com and have provided good results, and are still under due diligence for solver verification.

Technological innovations for a sustainable business model in the semiconductor industry

NASA Astrophysics Data System (ADS)

Levinson, Harry J.

2014-09-01

Increasing costs of wafer processing, particularly for lithographic processes, have made it increasingly difficult to achieve simultaneous reductions in cost-per-function and area per device. Multiple patterning techniques have made possible the fabrication of circuit layouts below the resolution limit of single optical exposures but have led to significant increases in the costs of patterning. Innovative techniques, such as self-aligned double patterning (SADP) have enabled good device performance when using less expensive patterning equipment. Other innovations have directly reduced the cost of manufacturing. A number of technical challenges must be overcome to enable a return to single-exposure patterning using short wavelength optical techniques, such as EUV patterning.

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds

PubMed Central

Poojary, Mahesha M.; Barba, Francisco J.; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A.; Juliano, Pablo

2016-01-01

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability. PMID:27879659

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds.

PubMed

Poojary, Mahesha M; Barba, Francisco J; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A; Juliano, Pablo

2016-11-22

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability.

SITE PROGRAM CURRENT AND FUTURE INNOVATIVE TECHNIQUES FOR GROUNDWATER TREATMENT

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) Office of Research and Development (ORD) conducts research related to the demonstration and evaluation of innovative cleanup technologies. One of the mechanisms for the evaluation of innovative field-scale technologies for hazardous ...

A Case of Problematic Diffusion: The Use of Sex Determination Techniques in India.

ERIC Educational Resources Information Center

Luthra, Rashmi

1994-01-01

Discussion of model shifts in diffusion research focuses on the growth in the use of sex determination techniques in India and their consequences relating to gender and power. Topics addressed include development, underdevelopment, and modernization; the adoption of innovations; and meanings of innovations within particular social systems.…

Innovative biomarkers in psychiatric disorders: a major clinical challenge in psychiatry.

PubMed

Lozupone, Madia; Seripa, Davide; Stella, Eleonora; La Montagna, Maddalena; Solfrizzi, Vincenzo; Quaranta, Nicola; Veneziani, Federica; Cester, Alberto; Sardone, Rodolfo; Bonfiglio, Caterina; Giannelli, Gianluigi; Bisceglia, Paola; Bringiotti, Roberto; Daniele, Antonio; Greco, Antonio; Bellomo, Antonello; Logroscino, Giancarlo; Panza, Francesco

2017-09-01

Currently, the diagnosis of psychiatric illnesses is based upon DSM-5 criteria. Although endophenotype-specificity for a particular disorder is discussed, the identification of objective biomarkers is ongoing for aiding diagnosis, prognosis, or clinical response to treatment. We need to improve the understanding of the biological abnormalities in psychiatric illnesses across conventional diagnostic boundaries. The present review investigates the innovative post-genomic knowledge used for psychiatric illness diagnostics and treatment response, with a particular focus on proteomics. Areas covered: This review underlines the contribution that psychiatric innovative biomarkers have reached in relation to diagnosis and theragnosis of psychiatric illnesses. Furthermore, it encompasses a reliable representation of their involvement in disease through proteomics, metabolomics/pharmacometabolomics and lipidomics techniques, including the possible role that gut microbiota and CYP2D6 polimorphisms may play in psychiatric illnesses. Expert opinion: Etiologic heterogeneity, variable expressivity, and epigenetics may impact clinical manifestations, making it difficult for a single measurement to be pathognomonic for multifaceted psychiatric disorders. Academic, industry, or government's partnerships may successfully identify and validate new biomarkers so that unfailing clinical tests can be developed. Proteomics, metabolomics, and lipidomics techniques are considered to be helpful tools beyond neuroimaging and neuropsychology for the phenotypic characterization of brain diseases.

Governing Methods: Policy Innovation Labs, Design and Data Science in the Digital Governance of Education

ERIC Educational Resources Information Center

Williamson, Ben

2015-01-01

Policy innovation labs are emerging knowledge actors and technical experts in the governing of education. The article offers a historical and conceptual account of the organisational form of the policy innovation lab. Policy innovation labs are characterised by specific methods and techniques of design, data science, and digitisation in public…

Differentiating innovation priorities among stakeholder in hospital care.

PubMed

Lambooij, Mattijs S; Hummel, Marjan J

2013-08-16

Decisions to adopt a particular innovation may vary between stakeholders because individual stakeholders may disagree on the costs and benefits involved. This may translate to disagreement between stakeholders on priorities in the implementation process, possibly explaining the slow diffusion of innovations in health care. In this study, we explore the differences in stakeholder preferences for innovations, and quantify the difference in stakeholder priorities regarding costs and benefits. The decision support technique called the analytic hierarchy process was used to quantify the preferences of stakeholders for nine information technology (IT) innovations in hospital care. The selection of the innovations was based on a literature review and expert judgments. Decision criteria related to the costs and benefits of the innovations were defined. These criteria were improvement in efficiency, health gains, satisfaction with care process, and investments required. Stakeholders judged the importance of the decision criteria and subsequently prioritized the selected IT innovations according to their expectations of how well the innovations would perform for these decision criteria. The stakeholder groups (patients, nurses, physicians, managers, health care insurers, and policy makers) had different preference structures for the innovations selected. For instance, self-tests were one of the innovations most preferred by health care insurers and managers, owing to their expected positive impacts on efficiency and health gains. However, physicians, nurses and patients strongly doubted the health gains of self-tests, and accordingly ranked self-tests as the least-preferred innovation. The various stakeholder groups had different expectations of the value of the nine IT innovations. The differences are likely due to perceived stakeholder benefits of each innovation, and less to the costs to individual stakeholder groups. This study provides a first exploratory quantitative insight into stakeholder positions concerning innovation in health care, and presents a novel way to study differences in stakeholder preferences. The results may be taken into account by decision makers involved in the implementation of innovations.

Differentiating innovation priorities among stakeholder in hospital care

PubMed Central

2013-01-01

Background Decisions to adopt a particular innovation may vary between stakeholders because individual stakeholders may disagree on the costs and benefits involved. This may translate to disagreement between stakeholders on priorities in the implementation process, possibly explaining the slow diffusion of innovations in health care. In this study, we explore the differences in stakeholder preferences for innovations, and quantify the difference in stakeholder priorities regarding costs and benefits. Methods The decision support technique called the analytic hierarchy process was used to quantify the preferences of stakeholders for nine information technology (IT) innovations in hospital care. The selection of the innovations was based on a literature review and expert judgments. Decision criteria related to the costs and benefits of the innovations were defined. These criteria were improvement in efficiency, health gains, satisfaction with care process, and investments required. Stakeholders judged the importance of the decision criteria and subsequently prioritized the selected IT innovations according to their expectations of how well the innovations would perform for these decision criteria. Results The stakeholder groups (patients, nurses, physicians, managers, health care insurers, and policy makers) had different preference structures for the innovations selected. For instance, self-tests were one of the innovations most preferred by health care insurers and managers, owing to their expected positive impacts on efficiency and health gains. However, physicians, nurses and patients strongly doubted the health gains of self-tests, and accordingly ranked self-tests as the least-preferred innovation. Conclusions The various stakeholder groups had different expectations of the value of the nine IT innovations. The differences are likely due to perceived stakeholder benefits of each innovation, and less to the costs to individual stakeholder groups. This study provides a first exploratory quantitative insight into stakeholder positions concerning innovation in health care, and presents a novel way to study differences in stakeholder preferences. The results may be taken into account by decision makers involved in the implementation of innovations. PMID:23947398

Development of an innovative solar absorber

NASA Astrophysics Data System (ADS)

Goodchild, Gavin

Solar thermal systems have great potential to replace or reduce the dependence of conventional fossil fuel based heating technologies required for space and water heating. Specifically solar domestic hot water systems can contribute 50-75% of the annual thermal load. To date residential users have been slow to purchase and install systems, primarily due to the large monetary investment required to purchase and install a system. Recent innovations in materials design and manufacturing techniques, offer opportunities for the development of absorber plate designs that have the potential to reduce cost, increase efficiency and reduce payback periods. Consequently, this design study was conducted in conjunction with industrial partners to develop an improved absorber based on roll bond manufacturing that can be produced at reduced cost with comparable or greater thermal efficiency.

Completing the puzzle: AOLI full-commissioning fresh results and AIV innovations

NASA Astrophysics Data System (ADS)

Velasco, S.; Colodro-Conde, C.; López, R. L.; Oscoz, A.; Valdivia, J. J. F.; Rebolo, R.; Femenía, B.; King, D. L.; Labadie, L.; Mackay, C.; Muthusubramanian, B.; Pérez-Garrido, A.; Puga, M.; Rodríguez-Coira, G.; Rodríguez-Ramos, L. F.; Rodríguez-Ramos, J. M.

2017-03-01

The Adaptive Optics Lucky Imager (AOLI) is a new instrument designed to combine adaptive optics (AO) and lucky imaging (LI) techniques to deliver high spatial resolution in the visible, about 20 mas, from ground-based telescopes. Here we present details of the integration and verification phases explaining the defiance that we have faced and the innovative and versatile solution of modular integration for each of its subsystems that we have developed. Modularity seems a clue key for opto-mechanical integration success in the extremely-big telescopes era. We present here the very fresh preliminary results after its first fully-working observing run on the WHT.

From Brainstorming to C-Sketch to Principles of Historical Innovators: Ideation Techniques to Enhance Student Creativity

ERIC Educational Resources Information Center

White, Christina; Wood, Kristin; Jensen, Dan

2012-01-01

The heart and soul of engineering is innovation and our ability to improve the human condition through design. To enrich engineering education, it is critical that we advance our teaching in innovation and design processes. This research focuses on the ideation component of innovation through the investigation of a suite of concept generation…

Autonomous formation flying based on GPS — PRISMA flight results

NASA Astrophysics Data System (ADS)

D'Amico, Simone; Ardaens, Jean-Sebastien; De Florio, Sergio

2013-01-01

This paper presents flight results from the early harvest of the Spaceborne Autonomous Formation Flying Experiment (SAFE) conducted in the frame of the Swedish PRISMA technology demonstration mission. SAFE represents one of the first demonstrations in low Earth orbit of an advanced guidance, navigation and control system for dual-spacecraft formations. Innovative techniques based on differential GPS-based navigation and relative orbital elements control are validated and tuned in orbit to fulfill the typical requirements of future distributed scientific instruments for remote sensing.

Web2Quests: Updating a Popular Web-Based Inquiry-Oriented Activity

ERIC Educational Resources Information Center

Kurt, Serhat

2009-01-01

WebQuest is a popular inquiry-oriented activity in which learners use Web resources. Since the creation of the innovation, almost 15 years ago, the Web has changed significantly, while the WebQuest technique has changed little. This article examines possible applications of new Web trends on WebQuest instructional strategy. Some possible…

Systematic Image Based Optical Alignment and Tensegrity

NASA Technical Reports Server (NTRS)

Zeiders, Glenn W.; Montgomery, Edward E, IV (Technical Monitor)

2001-01-01

This presentation will review the objectives and current status of two Small Business Innovative Research being performed by the Sirius Group, under the direction of MSFC. They all relate to the development of advanced optical systems technologies for automated segmented mirror alignment techniques and fundamental design methodologies for ultralight structures. These are important to future astronomical missions in space.

Laser Capture Microdissection Revisited as a Tool for Transcriptomic Analysis: Application of an Excel-Based qPCR Preparation Software (PREXCEL-Q)

USDA-ARS?s Scientific Manuscript database

The ability to reliably analyze cellular and molecular profiles of normal or diseased tissues is frequently obfuscated by the inherent heterogeneous nature of tissues. Laser Capture Microdissection (LCM) is an innovative technique that allows the isolation and enrichment of pure subpopulations of c...

TRAC Innovative Visualization Techniques

DTIC Science & Technology

2016-11-14

Therefore, TRAC analysts need a way to analyze the effectiveness of their visualization design choices. Currently, TRAC does not have a methodology ...to analyze visualizations used to support an analysis story. Our research team developed a visualization design methodology to create effective...visualizations that support an analysis story. First, we based our methodology on the latest research on design thinking, cognitive learning, and

An Innovative Plant Genomics and Gene Annotation Program for High School, Community College, and University Faculty

ERIC Educational Resources Information Center

Hacisalihoglu, Gokhan; Hilgert, Uwe; Nash, E. Bruce; Micklos, David A.

2008-01-01

Today's biology educators face the challenge of training their students in modern molecular biology techniques including genomics and bioinformatics. The Dolan DNA Learning Center (DNALC) of Cold Spring Harbor Laboratory has developed and disseminated a bench- and computer-based plant genomics curriculum for biology faculty. In 2007, a five-day…

Extreme-Teaching-2 (XT [superscript]2): Evaluation of an Innovative Semester-Long Intensive GTA Training Program Based on Microteaching

ERIC Educational Resources Information Center

Santandreu Calonge, David; Mark, Kai-Pan; Chiu, P. H. Patrio; Thadani, Dimple R.; Pun, Cecilia F. K.

2013-01-01

Microteaching techniques have been used for teacher training since the mid 1960s. Despite its usefulness, as affirmed by pre-service teachers, in-service teachers, and graduate teaching assistants (GTAs), there are numerous criticisms on the shortcomings of microteaching activities. Specifically, it (a) oversimplifies the classroom learning and…

Innovative Language-Based & Object-Oriented Structured AMR Using Fortran 90 and OpenMP

NASA Technical Reports Server (NTRS)

Norton, C.; Balsara, D.

1999-01-01

Parallel adaptive mesh refinement (AMR) is an important numerical technique that leads to the efficient solution of many physical and engineering problems. In this paper, we describe how AMR programing can be performed in an object-oreinted way using the modern aspects of Fortran 90 combined with the parallelization features of OpenMP.

Internet-Based Delphi Research: Case Based Discussion

PubMed Central

Donohoe, Holly M.; Stellefson, Michael L.

2013-01-01

The interactive capacity of the Internet offers benefits that are intimately linked with contemporary research innovation in the natural resource and environmental studies domains. However, e-research methodologies, such as the e-Delphi technique, have yet to undergo critical review. This study advances methodological discourse on the e-Delphi technique by critically assessing an e-Delphi case study. The analysis suggests that the benefits of using e-Delphi are noteworthy but the authors acknowledge that researchers are likely to face challenges that could potentially compromise research validity and reliability. To ensure that these issues are sufficiently considered when planning and designing an e-Delphi, important facets of the technique are discussed and recommendations are offered to help the environmental researcher avoid potential pitfalls associated with coordinating e-Delphi research. PMID:23288149

The application of welat latino for creating paes in solo wedding bride

NASA Astrophysics Data System (ADS)

Ihsani, Ade Novi Nurul; Krisnawati, Maria; Prasetyaningtyas, Wulansari; Anggraeni, Puput; Bela, Herlina Tria; Zunaedah, Putri Wahyu

2018-03-01

The purposes of this research were: 1) to find out the process of creating innovative welat, 2) to find out how to use innovative welat for Solo wedding bride paes creation. The method used in the research was research and development (R & D). Sampling technique in this research was purposive sampling by using 13 people as models. The data collection technique used observation and documentation. Data analysis technique used descriptive technique. The results of the study showed that 1) there were two times design change of the validity of welat creation, each product passed through several stages of designing, forming, determining the material and printing, 3) the first way of using the welat determined the distance dot between the cengkorongan of both forms by using welat according to the existed mold. In conclusion, Innovative welat can produce paes in accordance with the standard and shorten the process.

An Innovations-Based Noise Cancelling Technique on Inverse Kepstrum Whitening Filter and Adaptive FIR Filter in Beamforming Structure

PubMed Central

Jeong, Jinsoo

2011-01-01

This paper presents an acoustic noise cancelling technique using an inverse kepstrum system as an innovations-based whitening application for an adaptive finite impulse response (FIR) filter in beamforming structure. The inverse kepstrum method uses an innovations-whitened form from one acoustic path transfer function between a reference microphone sensor and a noise source so that the rear-end reference signal will then be a whitened sequence to a cascaded adaptive FIR filter in the beamforming structure. By using an inverse kepstrum filter as a whitening filter with the use of a delay filter, the cascaded adaptive FIR filter estimates only the numerator of the polynomial part from the ratio of overall combined transfer functions. The test results have shown that the adaptive FIR filter is more effective in beamforming structure than an adaptive noise cancelling (ANC) structure in terms of signal distortion in the desired signal and noise reduction in noise with nonminimum phase components. In addition, the inverse kepstrum method shows almost the same convergence level in estimate of noise statistics with the use of a smaller amount of adaptive FIR filter weights than the kepstrum method, hence it could provide better computational simplicity in processing. Furthermore, the rear-end inverse kepstrum method in beamforming structure has shown less signal distortion in the desired signal than the front-end kepstrum method and the front-end inverse kepstrum method in beamforming structure. PMID:22163987

Visualization of delamination in composite materials utilizing advanced X-ray imaging techniques

NASA Astrophysics Data System (ADS)

Vavrik, D.; Jakubek, J.; Jandejsek, I.; Krejci, F.; Kumpova, I.; Zemlicka, J.

2015-04-01

This work is focused on the development of instrumental radiographic methods for detection of delaminations in layered carbon fibre reinforced plastic composites used in the aerospace industry. The main limitation of current visualisation techniques is a very limited possibility to image so-called closed delaminations in which delaminated layers are in contact practically with no physical gap. In this contribution we report the development of innovative methods for closed delamination detection using an X-ray phase contrast technique for which the distance between delamination surfaces is not relevant. The approach is based on the energetic sensitivity of phase-enhanced radiography. Based on the applied methodology, we can distinguish both closed and open delamination. Further we have demonstrated the possibility to visualise open delaminations characterised by a physical gap between delaminated layers. This delamination type was successfully identified and visualized utilizing a high resolution and computed tomography table-top technique based on proper beam-hardening effect correction.

Managing Innovation.

ERIC Educational Resources Information Center

White, Ronald V.

The management of innovation in instruction in English as a second language can benefit from the experience and techniques of management in the world of commerce as well as from theories and procedures in education. A systematic approach to the management of innovation emphasizes the importance of clearly defined objectives, evaluation that…

The "All-Inside" Arthroscopic Broström Procedure Augmented With a Proximal Suture Anchor: An Innovative Technique.

PubMed

Cottom, James M; Richardson, Phillip E

Arthroscopic treatments of chronic lateral ankle stability have been reported in the literature. The authors report on an innovative technique augmenting the "All- Inside" Arthroscopic Broström procedure with an additional suture anchor. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Studies in astronomical time series analysis. IV - Modeling chaotic and random processes with linear filters

NASA Technical Reports Server (NTRS)

Scargle, Jeffrey D.

1990-01-01

While chaos arises only in nonlinear systems, standard linear time series models are nevertheless useful for analyzing data from chaotic processes. This paper introduces such a model, the chaotic moving average. This time-domain model is based on the theorem that any chaotic process can be represented as the convolution of a linear filter with an uncorrelated process called the chaotic innovation. A technique, minimum phase-volume deconvolution, is introduced to estimate the filter and innovation. The algorithm measures the quality of a model using the volume covered by the phase-portrait of the innovation process. Experiments on synthetic data demonstrate that the algorithm accurately recovers the parameters of simple chaotic processes. Though tailored for chaos, the algorithm can detect both chaos and randomness, distinguish them from each other, and separate them if both are present. It can also recover nonminimum-delay pulse shapes in non-Gaussian processes, both random and chaotic.

Research progress on the brewing techniques of new-type rice wine.

PubMed

Jiao, Aiquan; Xu, Xueming; Jin, Zhengyu

2017-01-15

As a traditional alcoholic beverage, Chinese rice wine (CRW) with high nutritional value and unique flavor has been popular in China for thousands of years. Although traditional production methods had been used without change for centuries, numerous technological innovations in the last decades have greatly impacted on the CRW industry. However, reviews related to the technology research progress in this field are relatively few. This article aimed at providing a brief summary of the recent developments in the new brewing technologies for making CRW. Based on the comparison between the conventional methods and the innovative technologies of CRW brewing, three principal aspects were summarized and sorted, including the innovation of raw material pretreatment, the optimization of fermentation and the reform of sterilization technology. Furthermore, by comparing the advantages and disadvantages of these methods, various issues are addressed related to the prospect of the CRW industry. Copyright © 2016 Elsevier Ltd. All rights reserved.

Antiviral Information Management System (AIMS): a prototype for operational innovation in drug development.

PubMed

Jadhav, Pravin R; Neal, Lauren; Florian, Jeff; Chen, Ying; Naeger, Lisa; Robertson, Sarah; Soon, Guoxing; Birnkrant, Debra

2010-09-01

This article presents a prototype for an operational innovation in knowledge management (KM). These operational innovations are geared toward managing knowledge efficiently and accessing all available information by embracing advances in bioinformatics and allied fields. The specific components of the proposed KM system are (1) a database to archive hepatitis C virus (HCV) treatment data in a structured format and retrieve information in a query-capable manner and (2) an automated analysis tool to inform trial design elements for HCV drug development. The proposed framework is intended to benefit drug development by increasing efficiency of dose selection and improving the consistency of advice from US Food and Drug Administration (FDA). It is also hoped that the framework will encourage collaboration among FDA, industry, and academic scientists to guide the HCV drug development process using model-based quantitative analysis techniques.

Innovation Abstracts; Volume XIV, 1992.

ERIC Educational Resources Information Center

Roueche, Suanne D., Ed.

1992-01-01

This series of 30 one- to two-page abstracts covering 1992 highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) faculty recognition and orientation; (2) the Amado M. Pena, Jr., Scholarship Program; (3) innovative teaching techniques, with individual abstracts…

Celebrating Two Decades of Innovation, 1968-1988.

ERIC Educational Resources Information Center

Goodwin, Gregory, Ed.

An interpretive overview is provided of the innovative instructional and managerial techniques implemented by the 16 member colleges of the League for Innovation in the Community College between 1968 and 1988. Chapter 1 reviews the origins and history of the League, highlighting its early (1968-75) emphasis on curriculum and instructional…

An Introduction to Simplified Performance Management Approaches. Report No. 98.

ERIC Educational Resources Information Center

Goddu, Roland

This guide to simplified performance management approaches contains five sections. The first section, entitled "Simple Techniques for Managing an Innovation," is written from the viewpoint of a principal as manager. It describes how to manage an innovation, develop an objective, allocate resources for the innovation, keep organized…

Internal corrosion monitoring of subsea oil and gas production equipment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joosten, M.W.; Fischer, K.P.; Strommen, R.

1995-04-01

Nonintrusive techniques will dominate subsea corrosion monitoring compared with the intrusive methods because such methods do not interfere with pipeline operations. The long-term reliability of the nonintrusive techniques in general is considered to be much better than that of intrusive-type probes. The nonintrusive techniques based on radioactive tracers (TLA, NA) and FSM and UT are expected to be the main types of subsea corrosion monitoring equipment in the coming years. Available techniques that could be developed specifically for subsea applications are: electrochemical noise, corrosion potentials (using new types of reference electrodes), multiprobe system for electrochemical measurements, and video camera inspectionmore » (mini-video camera with light source). The following innovative techniques have potential but need further development: ion selective electrodes, radioactive tracers, and Raman spectroscopy.« less

Recruitment Techniques and Strategies in a Community-Based Colorectal Cancer Screening Study of Men and Women of African Ancestry.

PubMed

Davis, Stacy N; Govindaraju, Swapamthi; Jackson, Brittany; Williams, Kimberly R; Christy, Shannon M; Vadaparampil, Susan T; Quinn, Gwendolyn P; Shibata, David; Roetzheim, Richard; Meade, Cathy D; Gwede, Clement K

Recruiting ethnically diverse Black participants to an innovative, community-based research study to reduce colorectal cancer screening disparities requires multipronged recruitment techniques. This article describes active, passive, and snowball recruitment techniques, and challenges and lessons learned in recruiting a diverse sample of Black participants. For each of the three recruitment techniques, data were collected on strategies, enrollment efficiency (participants enrolled/participants evaluated), and reasons for ineligibility. Five hundred sixty individuals were evaluated, and 330 individuals were enrolled. Active recruitment yielded the highest number of enrolled participants, followed by passive and snowball. Snowball recruitment was the most efficient technique, with enrollment efficiency of 72.4%, followed by passive (58.1%) and active (55.7%) techniques. There were significant differences in gender, education, country of origin, health insurance, and having a regular physician by recruitment technique (p < .05). Multipronged recruitment techniques should be employed to increase reach, diversity, and study participation rates among Blacks. Although each recruitment technique had a variable enrollment efficiency, the use of multipronged recruitment techniques can lead to successful enrollment of diverse Blacks into cancer prevention and control interventions.

Education of the modern surgical resident: novel approaches to learning in the era of the 80-hour workweek.

PubMed

Nguyen, Liz; Brunicardi, F Charles; Dibardino, Daniel J; Scott, Bradford G; Awad, Samir S; Bush, Ruth L; Brandt, Mary L

2006-06-01

Implementation of the 80-hour work week has resulted in limitations on the hours available for resident education, creating a need for innovative approaches to teach surgical residents successfully. Herein we report the methods and results of an innovative didactic learning program at a large academic surgical residency program. Between 2004 and 2005, based on known principles of adult education and innovative learning techniques, a didactic learning program was instituted in a major academic surgery program. The course work consisted of a structured reading program using Schwartz's Textbook of Surgery, with weekly testing and problem-based learning (PBL) groups led by surgical faculty. The residents' progress was assessed by American Board of Surgery In-Training Examination (ABSITE) training scores before and after program implementation. A resident survey was also conducted to assess residents' attitudes toward the new program. Results were reported as a mean, and categoric variables were compared using a paired Student's t-test. During the academic year of the structured reading program, the mean ABSITE score improved by 10% (P=0.02) from the previous year. The postgraduate year 4 class had the largest change, with a score increase of 17% over the previous year's performance (P=0.02). Survey results demonstrated that 64% of the responders agreed that the small-group PBL was preferable for achieving educational goals. Furthermore, 89% of residents responded that the PBL groups improved interaction between residents and faculty members. An innovative formal learning program based on a major surgical textbook with weekly testing and small group sessions can significantly improve surgical training in the modern era of work-hour restrictions. Furthermore, surgical trainees find this format to be innovative and useful for improving didactic teaching.

Concept Mapping as an Innovative Tool for the Assessment of Learning: An Experimental Experience among Business Management Degree Students

ERIC Educational Resources Information Center

Ruiz-Palomino, Pablo; Martinez-Canas, Ricardo

2013-01-01

In the search to improve the quality of education at the university level, the use of concept mapping is becoming an important instructional technique for enhancing the teaching-learning process. This educational tool is based on cognitive theories by making a distinction between learning by rote (memorizing) and learning by meaning, where…

A Research on the Construction of University R&D Management Team in China

ERIC Educational Resources Information Center

Jia, Ning

2007-01-01

The system of Chinese universities R&D as a branch of the system of the whole country R&D, has a great effect on the development and innovation of the country's science and technique. Consequently, it's important to construct an effective management team with high diathesis for University R&D management. Based on the statistics of the…

Nonlinear Dynamics and Heterogeneous Interacting Agents

NASA Astrophysics Data System (ADS)

Lux, Thomas; Reitz, Stefan; Samanidou, Eleni

Economic application of nonlinear dynamics, microscopic agent-based modelling, and the use of artificial intelligence techniques as learning devices of boundedly rational actors are among the most exciting interdisciplinary ventures of economic theory over the past decade. This volume provides us with a most fascinating series of examples on "complexity in action" exemplifying the scope and explanatory power of these innovative approaches.

Utilization of Innovations and Techniques of Educational Technology in Delivering of Educational Practicum and Its Impact on Increasing Academic Achievement among Pre-Service Teachers

ERIC Educational Resources Information Center

Ibrahim, Hatim G.

2017-01-01

The current study aims to identify the utilization of innovations and techniques of educational technology in teaching of educational practicum and its impact on increasing academic achievement among pre-service teachers. The study sample consisted of (60) pre-service teachers (student teachers) randomly selected from public middle and secondary…

Algorithm Building and Learning Programming Languages Using a New Educational Paradigm

NASA Astrophysics Data System (ADS)

Jain, Anshul K.; Singhal, Manik; Gupta, Manu Sheel

2011-08-01

This research paper presents a new concept of using a single tool to associate syntax of various programming languages, algorithms and basic coding techniques. A simple framework has been programmed in Python that helps students learn skills to develop algorithms, and implement them in various programming languages. The tool provides an innovative and a unified graphical user interface for development of multimedia objects, educational games and applications. It also aids collaborative learning amongst students and teachers through an integrated mechanism based on Remote Procedure Calls. The paper also elucidates an innovative method for code generation to enable students to learn the basics of programming languages using drag-n-drop methods for image objects.

Small Business Innovations

NASA Technical Reports Server (NTRS)

1996-01-01

Under a Small Business Innovation Research (SBIR) contract to Kennedy Space Center, EIC Laboratories invented a Raman Spectrograph with fiber optic sampling for space applications such as sensing hazardous fuel vapors and making on-board rapid analyses of chemicals and minerals. Raman spectroscopy is a laser-based measurement technique that provides through a unique vibrational spectrum a molecular 'fingerprint,' and can function in aqueous environments. EIC combined optical fiber technology with Raman methods to develop sensors that can be operated at a distance from the spectrographic analysis instruments and the laser excitation source. EIC refined and commercialized the technology to create the Fiber Optic Raman Spectrograph and the RamanProbe. Commercial applications range from process control to monitoring hazardous materials.

Discrimination of Closely-Spaced Geosynchronous Satellites - Phase Curve Analysis & New Small Business Innovative Research (SBIR) Efforts

NASA Astrophysics Data System (ADS)

Levan, P.

2010-09-01

Geosynchronous objects appear as unresolved blurs even when observed with the largest ground-based telescopes. Due to the lack of any spatial detail, two or more objects appearing at similar brightness levels within the spectral bandpass they are observed are difficult to distinguish. Observing a changing pattern of such objects from one time epoch to another showcases the deficiencies in associating individual objects before and after the configuration change. This paper explores solutions to this deficiency in the form of spectral (under small business innovative research) and phase curve analyses. The extension of the technique to phase curves proves to be a powerful new capability.

Evaluation and application of an innovative method based on various chitosan composites and Lemna gibba for boron removal from drinking water.

PubMed

Türker, Onur Can; Baran, Talat

2017-06-15

Boron exists in various types of water environments, and it is difficult and costly to remove B with conventional treatment methods from drinking water. Clearly, alternative and cost effective treatment techniques are imperative. In the present study, an innovative and environment friendly method based on hybrid systems consisting of various chitosan composite beads and Lemna gibba were evaluated for removal of B from drinking water. Our results from batch adsorption experiment indicated that a plant-based chitosan composite bead has a higher capacity of B removal than mineral-based chitosan composite beads. Almost 50% of total B removal was achieved using the hybrid system based on dried Lemna-chitosan composite beads and Lemna gibba combination in 4 days. Even at the high B concentration (8mgBL -1 ), B in drinking water could be reduced to less than 2.4mgL -1 when 0.05g plant-based chitosan composite beads and 12 Lemna fronds were used for 50mL test solution. Copyright © 2017 Elsevier Ltd. All rights reserved.

Innovative single-shot diagnostics for electrons from laser wakefield acceleration at FLAME

NASA Astrophysics Data System (ADS)

Bisesto, F. G.; Anania, M. P.; Cianchi, A.; Chiadroni, E.; Curcio, A.; Ferrario, M.; Pompili, R.; Zigler, A.

2017-07-01

Plasma wakefield acceleration is the most promising acceleration technique known nowadays, able to provide very high accelerating fields (> 100 GV/m), enabling acceleration of electrons to GeV energy in few centimeters. Here we present all the plasma related activities currently underway at SPARC_LAB exploiting the high power laser FLAME. In particular, we will give an overview of the single shot diagnostics employed: Electro Optic Sampling (EOS) for temporal measurement and Optical Transition Radiation (OTR) for an innovative one shot emittance measurements. In detail, the EOS technique has been employed to measure for the first time the longitudinal profile of electric field of fast electrons escaping from a solid target, driving the ions and protons acceleration, and to study the impact of using different target shapes. Moreover, a novel scheme for one shot emittance measurements based on OTR, developed and tested at SPARC_LAB LINAC, used in an experiment on electrons from laser wakefield acceleration still undergoing, will be shown.

Time-Domain Fluorescence Lifetime Imaging Techniques Suitable for Solid-State Imaging Sensor Arrays

PubMed Central

Li, David Day-Uei; Ameer-Beg, Simon; Arlt, Jochen; Tyndall, David; Walker, Richard; Matthews, Daniel R.; Visitkul, Viput; Richardson, Justin; Henderson, Robert K.

2012-01-01

We have successfully demonstrated video-rate CMOS single-photon avalanche diode (SPAD)-based cameras for fluorescence lifetime imaging microscopy (FLIM) by applying innovative FLIM algorithms. We also review and compare several time-domain techniques and solid-state FLIM systems, and adapt the proposed algorithms for massive CMOS SPAD-based arrays and hardware implementations. The theoretical error equations are derived and their performances are demonstrated on the data obtained from 0.13 μm CMOS SPAD arrays and the multiple-decay data obtained from scanning PMT systems. In vivo two photon fluorescence lifetime imaging data of FITC-albumin labeled vasculature of a P22 rat carcinosarcoma (BD9 rat window chamber) are used to test how different algorithms perform on bi-decay data. The proposed techniques are capable of producing lifetime images with enough contrast. PMID:22778606

Application of real-time digitization techniques in beam measurement for accelerators

NASA Astrophysics Data System (ADS)

Zhao, Lei; Zhan, Lin-Song; Gao, Xing-Shun; Liu, Shu-Bin; An, Qi

2016-04-01

Beam measurement is very important for accelerators. In this paper, modern digital beam measurement techniques based on IQ (In-phase & Quadrature-phase) analysis are discussed. Based on this method and high-speed high-resolution analog-to-digital conversion, we have completed three beam measurement electronics systems designed for the China Spallation Neutron Source (CSNS), Shanghai Synchrotron Radiation Facility (SSRF), and Accelerator Driven Sub-critical system (ADS). Core techniques of hardware design and real-time system calibration are discussed, and performance test results of these three instruments are also presented. Supported by National Natural Science Foundation of China (11205153, 10875119), Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-N27), and the Fundamental Research Funds for the Central Universities (WK2030040029),and the CAS Center for Excellence in Particle Physics (CCEPP).

Innovative Applications of Laser Scanning and Rapid Prototype Printing to Rock Breakdown Experiments

NASA Technical Reports Server (NTRS)

Bourke, Mary; Viles, Heather; Nicoll, Joe; Lyew-Ayee, Parris; Ghent, Rebecca; Holmlund, James

2008-01-01

We present the novel application of two technologies for use in rock breakdown experiments, i.e. close-range, ground-based 3D triangulation scanning and rapid prototype printing. These techniques aid analyses of form-process interactions across the range of scales relevant to breakdown (micron-m). This is achieved through (a) the creation of DEMs (which permit quantitative description and analysis of rock surface morphology and morphological change) and (b) the production of more realistically-shaped experimental blocks. We illustrate the use of these techniques, alongside appropriate data analysis routines, in experiments designed to investigate the persistence of fluvially-derived features in the face of subsequent wind abrasion and weathering. These techniques have a range of potential applications in experimental field and lab-based geomorphic studies beyond those specifically outlined here.

Privacy enhancing techniques - the key to secure communication and management of clinical and genomic data.

PubMed

De Moor, G J E; Claerhout, B; De Meyer, F

2003-01-01

To introduce some of the privacy protection problems related to genomics based medicine and to highlight the relevance of Trusted Third Parties (TTPs) and of Privacy Enhancing Techniques (PETs) in the restricted context of clinical research and statistics. Practical approaches based on two different pseudonymisation models, both for batch and interactive data collection and exchange, are described and analysed. The growing need of managing both clinical and genetic data raises important legal and ethical challenges. Protecting human rights in the realm of privacy, while optimising research potential and other statistical activities is a challenge that can easily be overcome with the assistance of a trust service provider offering advanced privacy enabling/enhancing solutions. As such, the use of pseudonymisation and other innovative Privacy Enhancing Techniques can unlock valuable data sources.

EAES recommendations on methodology of innovation management in endoscopic surgery.

PubMed

Neugebauer, Edmund A M; Becker, Monika; Buess, Gerhard F; Cuschieri, Alfred; Dauben, Hans-Peter; Fingerhut, Abe; Fuchs, Karl H; Habermalz, Brigitte; Lantsberg, Leonid; Morino, Mario; Reiter-Theil, Stella; Soskuty, Gabriela; Wayand, Wolfgang; Welsch, Thilo

2010-07-01

Under the mandate of the European Association for Endoscopic Surgery (EAES) a guideline on methodology of innovation management in endoscopic surgery has been developed. The primary focus of this guideline is patient safety, efficacy, and effectiveness. An international expert panel was invited to develop recommendations for the assessment and introduction of surgical innovations. A consensus development conference (CDC) took place in May 2009 using the method of a nominal group process (NGP). The recommendations were presented at the annual EAES congress in Prague, Czech Republic, on June 18th, 2009 for discussion and further input. After further Delphi processes between the experts, the final recommendations were agreed upon. The development and implementation of innovations in surgery are addressed in five sections: (1) definition of an innovation, (2) preclinical and (3) clinical scientific development, (4) scientific approval, and (5) implementation along with monitoring. Within the present guideline each of the sections and several steps are defined, and several recommendations based on available evidence have been agreed within each category. A comprehensive workflow of the different steps is given in an algorithm. In addition, issues of health technology assessment (HTA) serving to estimate efficiency followed by ethical directives are given. Innovations into clinical practice should be introduced with the highest possible grade of safety for the patient (nil nocere: do no harm). The recommendations can contribute to the attainment of this objective without preventing future promising diagnostic and therapeutic innovations in the field of surgery and allied techniques.

A Novel Fast and Secure Approach for Voice Encryption Based on DNA Computing

NASA Astrophysics Data System (ADS)

Kakaei Kate, Hamidreza; Razmara, Jafar; Isazadeh, Ayaz

2018-06-01

Today, in the world of information communication, voice information has a particular importance. One way to preserve voice data from attacks is voice encryption. The encryption algorithms use various techniques such as hashing, chaotic, mixing, and many others. In this paper, an algorithm is proposed for voice encryption based on three different schemes to increase flexibility and strength of the algorithm. The proposed algorithm uses an innovative encoding scheme, the DNA encryption technique and a permutation function to provide a secure and fast solution for voice encryption. The algorithm is evaluated based on various measures including signal to noise ratio, peak signal to noise ratio, correlation coefficient, signal similarity and signal frequency content. The results demonstrate applicability of the proposed method in secure and fast encryption of voice files

Innovation in surgical technology and techniques: Challenges and ethical issues.

PubMed

Geiger, James D; Hirschl, Ronald B

2015-06-01

The pace of medical innovation continues to increase. The deployment of new technologies in surgery creates many ethical challenges including how to determine safety of the technology, what is the timing and process for deployment of a new technology, how are patients informed before undergoing a new technology or technique, how are the outcomes of a new technology evaluated and how are the responsibilities of individual patients and society at large balanced. Ethical considerations relevant to the implementation of ECMO and robotic surgery are explored to further discussion of how we can optimize the delicate balance between innovation and regulation. Copyright © 2015 Elsevier Inc. All rights reserved.

The commercialization of optical techniques in Russian regions: experience and problems

NASA Astrophysics Data System (ADS)

Kartushina, Tatyana N.; Firsova, Anna A.

2005-06-01

In this article we made an attempt to consider some problems of Russia in the field of innovations. So the survey of situation with Russian innovation structures was given and also the necessity of region informatization was underlined. Moreover the basic problems in the field of innovations were revealed: the lack of experienced personal, bureaucracy barriers and not clear "rules of game" in the field of innovation activity. On top of that we were able to examine the activity of innovation enterprise ("Volgasvyazmontaj" Saratov, Russia).

Canadian regulatory perspectives on genome engineered crops

PubMed Central

Smyth, Stuart J.

2017-01-01

ABSTRACT New breeding techniques in plant agriculture exploded upon the scene about two years ago, in 2014. While these innovative plant breeding techniques, soon to be led by CRISPR/Cas9, initially appear to hold tremendous promise for plant breeding, if not a revolution for the industry, the question of how the products of these technologies will be regulated is rapidly becoming a key aspect of the technology's future potential. Regulation of innovative technologies and products has always lagged that of the science, but in the past decade, regulatory systems in many jurisdictions have become gridlocked as they try to regulate genetically modified (GM) crops. This regulatory incapability to efficiently assess and approve innovative new agricultural products is particularly important for new plant breeding techniques as if these techniques are classified as genetically modified breeding techniques, then their acceptance and future will diminish considerably as they will be rejected by the European Union. Conversely, if the techniques are accepted as conventional plant breeding, then the future is blindingly bright. This article examines the international debate about the regulation of new plant breeding techniques and then assesses how the Canadian regulatory system has approached the regulation of these technologies through two more public product approvals, GM apples and GM potatoes, then discusses other crop variety approval and those in the regulatory pipeline. PMID:27858499

Innovations in recreation management: importance, diffusion, and implementation.

Treesearch

Ingrid Schneider; Dorothy Anderson; Pamela Jakes

1993-01-01

Uses a Delphi technique to (1) identify important innovations in recreation resource management, (2) determine their relative importance in meeting recreation management objectives, (3) and gather information about their diffusion and implementation.

Risk assessment for public–private partnerships : a primer.

DOT National Transportation Integrated Search

2014-01-01

The Federal Highway Administrations (FHWAs) Office of Innovative Program Delivery (IPD) assists States and local governments in developing knowledge, skills, and abilities in innovative finance techniques. Publicprivate partnerships (P3s) ar...

Defense Small Business Innovation Research Program (SBIR). Volume 1. Army Abstracts of Phase 1 Awards 1991

DTIC Science & Technology

1991-01-01

Office: MICOM HUNTSVILLE, AL 35805 Contract #: DAAHO1-92-C-R150 Phone: (205) 876-7502 Pi: D. BRETI BEASLEY Title: INFRARED LASER DIODE BASED INFRARED ...TECHNIQUES WILL BE INVESTIGATED TO DESIGN A FORM FIT GIMBALL-MOUNTED 94 GHZ/ INFRARED FOCAL PLANE ARRAY DUAL-MODE MISSILE SEEKER SENSOR BASED ON LOW...RESOLUTION AT 94 GHZ AND A 128X128 ARRAY IR IMAGE PROCESSING FOR AUTONOMOUS TARGET RECOGNITION AND AIMPOINT SELECTION. THE 94 GHZ AND INFRARED ELECTRONICS

Value Innovation in Learner-Centered Design. How to Develop Valuable Learning Tools

ERIC Educational Resources Information Center

Breuer, Henning; Schwarz, Heinrich; Feller, Kristina; Matsumoto, Mitsuji

2014-01-01

This paper shows how to address technological, cultural and social transformations with empirically grounded innovation. Areas in transition such as higher education and learning techniques today bring about new needs and opportunities for innovative tools and services. But how do we find these tools? The paper argues for using a strategy of…

Ten Reasons for IT Educators to Be Early Adopters of IT Innovations

ERIC Educational Resources Information Center

Gillard, Sharlett; Bailey, Denice; Nolan, Ernest

2008-01-01

Professionals in the information technology field are bombarded with an incessant stream of innovations in hardware and software as well as practices, methods, and techniques. IT educators are among the first targets in the market and must decide if and when to adopt these innovations in their instruction of students and professional endeavors.…

Evidence for an inhibitory-control theory of the reasoning brain.

PubMed

Houdé, Olivier; Borst, Grégoire

2015-01-01

In this article, we first describe our general inhibitory-control theory and, then, we describe how we have tested its specific hypotheses on reasoning with brain imaging techniques in adults and children. The innovative part of this perspective lies in its attempt to come up with a brain-based synthesis of Jean Piaget's theory on logical algorithms and Daniel Kahneman's theory on intuitive heuristics.

Direct Global Measurements of Tropspheric Winds Employing a Simplified Coherent Laser Radar using Fully Scalable Technology and Technique

NASA Technical Reports Server (NTRS)

Kavaya, Michael J.; Spiers, Gary D.; Lobl, Elena S.; Rothermel, Jeff; Keller, Vernon W.

1996-01-01

Innovative designs of a space-based laser remote sensing 'wind machine' are presented. These designs seek compatibility with the traditionally conflicting constraints of high scientific value and low total mission cost. Mission cost is reduced by moving to smaller, lighter, more off-the-shelf instrument designs which can be accommodated on smaller launch vehicles.

Law and Order in Grade 6-E: A Story of Chaos and Innovation in a Ghetto School.

ERIC Educational Resources Information Center

Marshall, M. Kimbrough

This book deals with the development and details of a variant of the open classroom technique, based upon the author's experiences as a sixth grade teacher at the Martin Luther King, Jr. Roxbury Massachusetts Middle School. The system has four major differences from conventional classrooms: (1) Kids sit in groups spread around the room rather than…

Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional Chinese medicine.

PubMed

Song, Guanli; Wang, Yinghui; Zhang, Runshun; Liu, Baoyan; Zhou, Xuezhong; Zhou, Xiaji; Zhang, Hong; Guo, Yufeng; Xue, Yanxing; Xu, Lili

2014-09-01

The current modes of experience inheritance from famous specialists in traditional Chinese medicine (TCM) include master and disciple, literature review, clinical-epidemiology-based clinical research observation, and analysis and data mining via computer and database technologies. Each mode has its advantages and disadvantages. However, a scientific and instructive experience inheritance mode has not been developed. The advent of the big data era as well as the formation and practice accumulation of the TCM clinical research paradigm in the real world have provided new perspectives, techniques, and methods for inheriting experience from famous TCM specialists. Through continuous exploration and practice, the research group proposes the innovation research mode based on the real-world TCM clinical research paradigm, which involves the inheritance and innovation of the existing modes. This mode is formulated in line with its own development regularity of TCM and is expected to become the main mode of experience inheritance in the clinical field.

Financial structuring and assessment for public–private partnerships : a primer.

DOT National Transportation Integrated Search

2013-12-01

The Federal Highway Administrations (FHWAs) Office of Innovative Program Delivery (IPD) assists States and local governments in developing knowledge, skills, and abilities in innovative finance techniques. Publicprivate partnerships (P3s) ar...

Application of Rapid Prototyping and Wire Arc Spray to the Fabrication of Injection Mold Tools (MSFC Center Director's Discretionary Fund)

NASA Technical Reports Server (NTRS)

Cooper, K. G.

2000-01-01

Rapid prototyping (RP) is a layer-by-layer-based additive manufacturing process for constructing three-dimensional representations of a computer design from a wax, plastic, or similar material. Wire arc spray (WAS) is a metal spray forming technique, which deposits thin layers of metal onto a substrate or pattern. Marshall Space Flight Center currently has both capabilities in-house, and this project proposed merging the two processes into an innovative manufacturing technique, in which intermediate injection molding tool halves were to be fabricated with RP and WAS metal forming.

Characterization and reclamation assessment for the Central Shops Diesel Storage Facility, Savannah River Site, Aiken, South Carolina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fliermans, C.B.; Hazen, T.C.; Bledsoe, H.

1993-10-01

The contamination of subsurface terrestrial environments by organic contaminants is a global phenomenon. The remediation of such environments requires innovative assessment techniques and strategies for successful clean-ups. Central Shops Diesel Storage Facility at Savannah River Site was characterized to determine the extent of subsurface diesel fuel contamination using innovative approaches and effective bioremediation techniques for clean-up of the contaminant plume have been established.

Preliminary Evaluation of BIM-based Approaches for Schedule Delay Analysis

NASA Astrophysics Data System (ADS)

Chou, Hui-Yu; Yang, Jyh-Bin

2017-10-01

The problem of schedule delay commonly occurs in construction projects. The quality of delay analysis depends on the availability of schedule-related information and delay evidence. More information used in delay analysis usually produces more accurate and fair analytical results. How to use innovative techniques to improve the quality of schedule delay analysis results have received much attention recently. As Building Information Modeling (BIM) technique has been quickly developed, using BIM and 4D simulation techniques have been proposed and implemented. Obvious benefits have been achieved especially in identifying and solving construction consequence problems in advance of construction. This study preforms an intensive literature review to discuss the problems encountered in schedule delay analysis and the possibility of using BIM as a tool in developing a BIM-based approach for schedule delay analysis. This study believes that most of the identified problems can be dealt with by BIM technique. Research results could be a fundamental of developing new approaches for resolving schedule delay disputes.

Contamination detection NDE for cleaning process inspection

NASA Technical Reports Server (NTRS)

Marinelli, W. J.; Dicristina, V.; Sonnenfroh, D.; Blair, D.

1995-01-01

In the joining of multilayer materials, and in welding, the cleanliness of the joining surface may play a large role in the quality of the resulting bond. No non-intrusive techniques are currently available for the rapid measurement of contamination on large or irregularly shaped structures prior to the joining process. An innovative technique for the measurement of contaminant levels in these structures using laser based imaging is presented. The approach uses an ultraviolet excimer laser to illuminate large and/or irregular surface areas. The UV light induces fluorescence and is scattered from the contaminants. The illuminated area is viewed by an image-intensified CCD (charge coupled device) camera interfaced to a PC-based computer. The camera measures the fluorescence and/or scattering from the contaminants for comparison with established standards. Single shot measurements of contamination levels are possible. Hence, the technique may be used for on-line NDE testing during manufacturing processes.

Innovative Techniques for Evaluating Behavioral Nutrition Interventions1234

PubMed Central

Laugero, Kevin D; Cunningham, Brian T; Lora, Karina R; Reicks, Marla

2017-01-01

Assessing outcomes and the impact from behavioral nutrition interventions has remained challenging because of the lack of methods available beyond traditional nutrition assessment tools and techniques. With the current high global obesity and related chronic disease rates, novel methods to evaluate the impact of behavioral nutrition-based interventions are much needed. The objective of this narrative review is to describe and review the current status of knowledge as it relates to 4 different innovative methods or tools to assess behavioral nutrition interventions. Methods reviewed include 1) the assessment of stress and stress responsiveness to enhance the evaluation of nutrition interventions, 2) eye-tracking technology in nutritional interventions, 3) smartphone biosensors to assess nutrition and health-related outcomes, and 4) skin carotenoid measurements to assess fruit and vegetable intake. Specifically, the novel use of functional magnetic resonance imaging, by characterizing the brain’s responsiveness to an intervention, can help researchers develop programs with greater efficacy. Similarly, if eye-tracking technology can enable researchers to get a better sense as to how participants view materials, the materials may be better tailored to create an optimal impact. The latter 2 techniques reviewed, smartphone biosensors and methods to detect skin carotenoids, can provide the research community with portable, effective, nonbiased ways to assess dietary intake and quality and more in the field. The information gained from using these types of methodologies can improve the efficacy and assessment of behavior-based nutrition interventions. PMID:28096132

[Nudge in prevention… an alternative approach or a dead end?].

PubMed

Cambon, Linda

2016-01-01

Prevention policies need to be more effective. Practitioners and decision-makers therefore need to innovate in the field of prevention policies and interventions by adapting methods or strategies used in other domains. Nudges, considered to be an attractive technique in view of its efficacy, are one of these innovations.However, the use of nudges in prevention policies raises ethical debates which will be summarized in this article. After recalling the definition of nudging, this article describes the ethical debates concerning three issues and emphasizes the way they can reflect a beneficial, democratic, freedom-based and autonomous society.In conclusion, this article encourages prevention practitioners and decision-makers to adopt a larger view before transferring strategies from other sectors and especially to consider all ethical issues.

SOIL AND SEDIMENT SAMPLING METHODS

EPA Science Inventory

The EPA Office of Solid Waste and Emergency Response's (OSWER) Office of Superfund Remediation and Technology Innovation (OSRTI) needs innovative methods and techniques to solve new and difficult sampling and analytical problems found at the numerous Superfund sites throughout th...

48 CFR 15.602 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Government to encourage the submission of new and innovative ideas in response to Broad Agency Announcements... new and innovative ideas do not fall under topic areas publicized under those programs or techniques, the ideas may be submitted as unsolicited proposals. ...

Ambroise Paré (1510-1590) and His Innovative Work on the Treatment of War Injuries.

PubMed

Markatos, Konstantinos; Tzivra, Anna; Tsoutsos, Spyridon; Tsourouflis, Gerasimos; Karamanou, Marianna; Androutsos, Georgios

2018-04-01

The purpose of this study is to summarize the innovations of Ambroise Paré (1510-1590) on the treatment of war wounds and improving amputation technique through ligature in arteries and veins. Ambroise Paré debunked the widely accepted idea that gun powder was poisonous for wounds. He also minimized the use of cautery of wounds by his dressing methods and the application of ligature during amputations. All these innovative rationales revolutionized the practice of war surgery during the Renaissance and paved the way for the introduction of modern surgery. Nevertheless, although his wound dressing innovations became widely accepted, the same did not happen with ligature and amputation; those techniques could become widely applicable if one could somehow control bleeding until the blood vessels had been tied. This became possible much later in the 18th century when Jean Louis Petit invented the first useful and efficient tourniquet.

Imaging live cells at high spatiotemporal resolution for lab-on-a-chip applications.

PubMed

Chin, Lip Ket; Lee, Chau-Hwang; Chen, Bi-Chang

2016-05-24

Conventional optical imaging techniques are limited by the diffraction limit and difficult-to-image biomolecular and sub-cellular processes in living specimens. Novel optical imaging techniques are constantly evolving with the desire to innovate an imaging tool that is capable of seeing sub-cellular processes in a biological system, especially in three dimensions (3D) over time, i.e. 4D imaging. For fluorescence imaging on live cells, the trade-offs among imaging depth, spatial resolution, temporal resolution and photo-damage are constrained based on the limited photons of the emitters. The fundamental solution to solve this dilemma is to enlarge the photon bank such as the development of photostable and bright fluorophores, leading to the innovation in optical imaging techniques such as super-resolution microscopy and light sheet microscopy. With the synergy of microfluidic technology that is capable of manipulating biological cells and controlling their microenvironments to mimic in vivo physiological environments, studies of sub-cellular processes in various biological systems can be simplified and investigated systematically. In this review, we provide an overview of current state-of-the-art super-resolution and 3D live cell imaging techniques and their lab-on-a-chip applications, and finally discuss future research trends in new and breakthrough research areas of live specimen 4D imaging in controlled 3D microenvironments.

Real -time dispatching modelling for trucks with different capacities in open pit mines / Modelowanie w czasie rzeczywistym przewozów ciężarówek o różnej ładowności w kopalni odkrywkowej

NASA Astrophysics Data System (ADS)

Ahangaran, Daryoush Kaveh; Yasrebi, Amir Bijan; Wetherelt, Andy; Foster, Patrick

2012-10-01

Application of fully automated systems for truck dispatching plays a major role in decreasing the transportation costs which often represent the majority of costs spent on open pit mining. Consequently, the application of a truck dispatching system has become fundamentally important in most of the world's open pit mines. Recent experiences indicate that by decreasing a truck's travelling time and the associated waiting time of its associated shovel then due to the application of a truck dispatching system the rate of production will be considerably improved. Computer-based truck dispatching systems using algorithms, advanced and accurate software are examples of these innovations. Developing an algorithm of a computer- based program appropriated to a specific mine's conditions is considered as one of the most important activities in connection with computer-based dispatching in open pit mines. In this paper the changing trend of programming and dispatching control algorithms and automation conditions will be discussed. Furthermore, since the transportation fleet of most mines use trucks with different capacities, innovative methods, operational optimisation techniques and the best possible methods for developing the required algorithm for real-time dispatching are selected by conducting research on mathematical-based planning methods. Finally, a real-time dispatching model compatible with the requirement of trucks with different capacities is developed by using two techniques of flow networks and integer programming.

PhAST: pharmacophore alignment search tool.

PubMed

Hähnke, Volker; Hofmann, Bettina; Grgat, Tomislav; Proschak, Ewgenij; Steinhilber, Dieter; Schneider, Gisbert

2009-04-15

We present a ligand-based virtual screening technique (PhAST) for rapid hit and lead structure searching in large compound databases. Molecules are represented as strings encoding the distribution of pharmacophoric features on the molecular graph. In contrast to other text-based methods using SMILES strings, we introduce a new form of text representation that describes the pharmacophore of molecules. This string representation opens the opportunity for revealing functional similarity between molecules by sequence alignment techniques in analogy to homology searching in protein or nucleic acid sequence databases. We favorably compared PhAST with other current ligand-based virtual screening methods in a retrospective analysis using the BEDROC metric. In a prospective application, PhAST identified two novel inhibitors of 5-lipoxygenase product formation with minimal experimental effort. This outcome demonstrates the applicability of PhAST to drug discovery projects and provides an innovative concept of sequence-based compound screening with substantial scaffold hopping potential. 2008 Wiley Periodicals, Inc.

INNOVATIONS IN EQUIPMENT AND TECHNIQUES FOR THE BIOLOGY TEACHING LABORATORY.

ERIC Educational Resources Information Center

BARTHELEMY, RICHARD E.; AND OTHERS

LABORATORY TECHNIQUES AND EQUIPMENT APPROPRIATE FOR TEACHING BIOLOGICAL SCIENCE CURRICULUM STUDY BIOLOGY ARE EMPHASIZED. MAJOR CATEGORIES INCLUDE (1) LABORATORY FACILITIES, (2) EQUIPMENT AND TECHNIQUES FOR CULTURE OF MICRO-ORGANISMS, (3) LABORATORY ANIMALS AND THEIR HOUSING, (4) TECHNIQUES FOR STUDYING PLANT GROWTH, (5) TECHNIQUES FOR STUDYING…

Modeling the Innovation-Decision Process: Dissemination and Adoption of a Motivational Interviewing Preparatory Procedure in Addiction Outpatient Clinics

PubMed Central

Walitzer, Kimberly S.; Dermen, Kurt H.; Barrick, Christopher; Shyhalla, Kathleen

2015-01-01

Widespread adoption of empirically-supported treatment innovations has the potential to improve effectiveness of treatment received by individuals with substance use disorders. However, the process of disseminating such innovations has been complex, slow, and difficult. We empirically describe the dissemination and adoption of a treatment innovation – an alcohol-treatment preparatory therapeutic procedure based on motivational interviewing (MI) – in the context of Rogers’ (2003) five stages of innovation-decision process (knowledge, persuasion, decision, implementation and confirmation). To this end, 145 randomly-chosen outpatient addiction treatment clinics in New York State received an onsite visit from a project trainer delivering one of three randomly-assigned dissemination intensities: a 15-minute, a half-day or a full-day presentation. Across these clinics, 141 primary administrators and 837 clinicians completed questionnaires assessing aspects of five innovation-decision stages. At each clinic, questionnaire administration occurred immediately pre- and post-dissemination, as well as one and six months after dissemination. Consistent with Rogers’ theory, earlier stages of the innovation-decision process predicted later stages. As hypothesized, dissemination intensity predicted clinicians’ post-dissemination knowledge. Clinician baseline characteristics (including gender, pre-dissemination knowledge regarding the MI preparatory technique, education, case load, beliefs regarding the nature of alcohol problems, and beliefs and behavior with regard to therapeutic style) predicted knowledge and persuasion stage variables. One baseline clinic characteristic (i.e., clinic mean beliefs and behavior regarding an MI-consistent therapeutic style) predicted implementation stage variables. Findings suggest that dissemination strategies should accommodate clinician and clinic characteristics. PMID:25934460

Research on Upgrade Path to Technology Innovation of Resource-based SMEs in China

NASA Astrophysics Data System (ADS)

Jie, Xu

2017-08-01

Complexity, diversity and coordination are features of technology innovation of resource-based SMEs in China. This paper studies on the key factors of macro-environment, cooperation among enterprises and enterprise interior, which influence the upgrading of technology innovation of resource-based SMEs in China. This paper constructs integrated system of technology innovation to analyse the upgrade path to technology innovation of resource-based SMEs in China, so that enterprises would improve their technology innovation and get a new way to accomplish sustainable innovated development.

Flow-based analysis using microfluidics-chemiluminescence systems.

PubMed

Al Lawati, Haider A J

2013-01-01

This review will discuss various approaches and techniques in which analysis using microfluidics-chemiluminescence systems (MF-CL) has been reported. A variety of applications is examined, including environmental, pharmaceutical, biological, food and herbal analysis. Reported uses of CL reagents, sample introduction techniques, sample pretreatment methods, CL signal enhancement and detection systems are discussed. A hydrodynamic pumping system is predominately used for these applications. However, several reports are available in which electro-osmotic (EO) pumping has been implemented. Various sample pretreatment methods have been used, including liquid-liquid extraction, solid-phase extraction and molecularly imprinted polymers. A wide range of innovative techniques has been reported for CL signal enhancement. Most of these techniques are based on enhancement of the mixing process in the microfluidics channels, which leads to enhancement of the CL signal. However, other techniques are also reported, such as mirror reaction, liquid core waveguide, on-line pre-derivatization and the use of an opaque white chip with a thin transparent seal. Photodetectors are the most commonly used detectors; however, other detection systems have also been used, including integrated electrochemiluminescence (ECL) and organic photodiodes (OPDs). Copyright © 2012 John Wiley & Sons, Ltd.

What does an innovative teaching assignment strategy mean to nursing students?

PubMed

Neuman, Lois H; Pardue, Karen T; Grady, Janet L; Gray, Mary Tod; Hobbins, Bonnie; Edelstein, Jan; Herrman, Judith W

2009-01-01

The concept of innovation in nursing education has been addressed in published literature on faculty-defined and faculty-created teaching strategies and instructional methods. In this project, innovation is defined as "using knowledge to create ways and services that are new (or perceived as new) in order to transform systems" (Pardue, Tagliareni, Valiga, Davison-Price, & Orchowsky, 2005). Studies on nursing student perceptions of innovation are limited, and it is unclear how undergraduate and graduate students conceptualize innovative learning experiences. This project explored students' perceptions of their experiences with instructor-defined, innovative teaching/learning strategies in four types of nursing education programs. Issues nurse educators should consider as they apply new techniques to their teaching are discussed.

Knowledge Innovation System: The Common Language.

ERIC Educational Resources Information Center

Rogers, Debra M. Amidon

1993-01-01

The Knowledge Innovation System is a management technique in which a networked enterprise uses knowledge flow as a collaborative advantage. Enterprise Management System-Architecture, which can be applied to collaborative activities, has five domains: economic, sociological, psychological, managerial, and technological. (SK)

INNOVATIVE METHODS FOR EMISSION INVENTORY DEVELOPMENT AND EVALUATION: WORKSHOP SYNTHESIS

EPA Science Inventory

Emission inventories are key databases for evaluating, managing, and regulating air pollutants. Refinements and innovations in instruments that measure air pollutants, models that calculate emissions, and techniques for data management and uncertainty assessment are critical to ...

48 CFR 15.602 - Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., Small Business Innovation Research topics, Small Business Technology Transfer Research topics, Program Research and Development Announcements, or any other Government-initiated solicitation or program. When the new and innovative ideas do not fall under topic areas publicized under those programs or techniques...

48 CFR 15.602 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., Small Business Innovation Research topics, Small Business Technology Transfer Research topics, Program Research and Development Announcements, or any other Government-initiated solicitation or program. When the new and innovative ideas do not fall under topic areas publicized under those programs or techniques...

48 CFR 15.602 - Policy.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., Small Business Innovation Research topics, Small Business Technology Transfer Research topics, Program Research and Development Announcements, or any other Government-initiated solicitation or program. When the new and innovative ideas do not fall under topic areas publicized under those programs or techniques...

If You Build It, They Will Come: How to Establish an Academic Innovation Enterprise.

PubMed

Srimathveeravalli, Govindarajan; Balesh, Elie; Cheng, Christopher P; Chen, David

2017-06-01

The rapid growth of minimally invasive, image-guided intervention has redefined the procedural management of multiple disease entities. The process of innovation which has characterized the growth of interventional radiology can be best described as "needs-based," whereby practicing interventionalists identify unmet clinical needs and subsequently invent solutions to achieve desired technical and clinical outcomes. Historically, catheters and other percutaneous devices were developed with rudimentary manufacturing techniques and subsequently translated to patients with relatively little regulatory oversight. Since then, the resources required and financial costs of interventional technology development have grown exponentially. Fortunately, advances in software development, new methods of rapid prototyping, and commoditization of hardware components have made in-house engineering feasible once again. This has created an opportunity for academic medical centers to translate their research into testable prototypes in humans sooner and at reduced costs, and academic interventional radiology divisions are now leveraging these developments to create collaborative centers of innovation. This article describes five such organizational formats for collaboration and innovation in the academic setting, describing the structure, opportunities, requirements, and caveats of each model. Copyright © 2017 Elsevier Inc. All rights reserved.

Evidence for an inhibitory-control theory of the reasoning brain

PubMed Central

Houdé, Olivier; Borst, Grégoire

2015-01-01

In this article, we first describe our general inhibitory-control theory and, then, we describe how we have tested its specific hypotheses on reasoning with brain imaging techniques in adults and children. The innovative part of this perspective lies in its attempt to come up with a brain-based synthesis of Jean Piaget’s theory on logical algorithms and Daniel Kahneman’s theory on intuitive heuristics. PMID:25852528

Using the Internet to Improve HRD Research: The Case of the Web-Based Delphi Research Technique to Achieve Content Validity of an HRD-Oriented Measurement

ERIC Educational Resources Information Center

Hatcher, Tim; Colton, Sharon

2007-01-01

Purpose: The purpose of this article is to highlight the results of the online Delphi research project; in particular the procedures used to establish an online and innovative process of content validation and obtaining "rich" and descriptive information using the internet and current e-learning technologies. The online Delphi was proven to be an…

Final Report for the ZERT Project: Basic Science of Retention Issues, Risk Assessment & Measurement, Monitoring and Verification for Geologic Sequestration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spangler, Lee; Cunningham, Alfred; Lageson, David

2011-03-31

ZERT has made major contributions to five main areas of sequestration science: improvement of computational tools; measurement and monitoring techniques to verify storage and track migration of CO{sub 2}; development of a comprehensive performance and risk assessment framework; fundamental geophysical, geochemical and hydrological investigations of CO{sub 2} storage; and investigate innovative, bio-based mitigation strategies.

[Hygienic and ergonomic analysis of the technology for sinking main and subsidiary mine shafts].

PubMed

Meniaĭlo, N I; Tyshlek, E G; Gritsenko, V S; Shemiakin, G M

1989-01-01

The labour conditions in mine shafts do not correspond to the existing ergonomic and hygienic norms. Drilling and blasting techniques are most hazardous as to the gravity and duration of the factors involved. Working conditions normalization should be based on the elaboration of specifically innovative technologies which should envisage the workers' periodic staying in the mine shaft area during the work shift.

Numerical simulations of mechanical properties of innovative pothole patching materials featuring high toughness, low viscosity nano-molecular resins

NASA Astrophysics Data System (ADS)

Yuan, K. Y.; Yuan, W.; Ju, J. W.; Yang, J. M.; Kao, W.; Carlson, L.

2012-04-01

As asphalt pavements age and deteriorate, recurring pothole repair failures and propagating alligator cracks in the asphalt pavements have become a serious issue to our daily life and resulted in high repairing costs for pavement and vehicles. To solve this urgent issue, pothole repair materials with superior durability and long service life are needed. In the present work, revolutionary pothole patching materials with high toughness, high fatigue resistance that are reinforced with nano-molecular resins have been developed to enhance their resistance to traffic loads and service life of repaired potholes. In particular, DCPD resin (dicyclopentadiene, C10H12) with a Rhuthinium-based catalyst is employed to develop controlled properties that are compatible with aggregates and asphalt binders. In this paper, a multi-level numerical micromechanics-based model is developed to predict the mechanical properties of these innovative nanomolecular resin reinforced pothole patching materials. Coarse aggregates in the finite element analysis are modeled as irregular shapes through image processing techniques and randomly-dispersed coated particles. The overall properties of asphalt mastic, which consists of fine aggregates, asphalt binder, cured DCPD and air voids are theoretically estimated by the homogenization technique of micromechanics. Numerical predictions are compared with suitably designed experimental laboratory results.

Novel GM animal technologies and their governance.

PubMed

Bruce, Ann; Castle, David; Gibbs, Corrina; Tait, Joyce; Whitelaw, C Bruce A

2013-08-01

Scientific advances in methods of producing genetically modified (GM) animals continue, yet few such animals have reached commercial production. Existing regulations designed for early techniques of genetic modification pose formidable barriers to commercial applications. Radically improved techniques for producing GM animals invite a re-examination of current regulatory regimes. We critically examine current GM animal regulations, with a particular focus on the European Union, through a framework that recognises the importance of interactions among regulatory regimes, innovation outcomes and industry sectors. The current focus on the regulation of risk is necessary but is unable to discriminate among applications and tends to close down broad areas of application rather than facilitate innovation and positive industry interactions. Furthermore, the fields of innovative animal biosciences appear to lack networks of organisations with co-ordinated future oriented actions. Such networks could drive coherent programmes of innovation towards particular visions and contribute actively to the development of regulatory systems for GM animals. The analysis presented makes the case for regulatory consideration of each animal bioscience related innovation on the basis of the nature of the product itself and not the process by which it was developed.

Design and fabrication of a sleep apnea device using computer-aided design/additive manufacture technologies.

PubMed

Al Mortadi, Noor; Eggbeer, Dominic; Lewis, Jeffrey; Williams, Robert J

2013-04-01

The aim of this study was to analyze the latest innovations in additive manufacture techniques and uniquely apply them to dentistry, to build a sleep apnea device requiring rotating hinges. Laser scanning was used to capture the three-dimensional topography of an upper and lower dental cast. The data sets were imported into an appropriate computer-aided design software environment, which was used to design a sleep apnea device. This design was then exported as a stereolithography file and transferred for three-dimensional printing by an additive manufacture machine. The results not only revealed that the novel computer-based technique presented provides new design opportunities but also highlighted limitations that must be addressed before the techniques can become clinically viable.

History of the Innovation of Damage Control for Management of Trauma Patients: 1902-2016.

PubMed

Roberts, Derek J; Ball, Chad G; Feliciano, David V; Moore, Ernest E; Ivatury, Rao R; Lucas, Charles E; Fabian, Timothy C; Zygun, David A; Kirkpatrick, Andrew W; Stelfox, Henry T

2017-05-01

To review the history of the innovation of damage control (DC) for management of trauma patients. DC is an important development in trauma care that provides a valuable case study in surgical innovation. We searched bibliographic databases (1950-2015), conference abstracts (2009-2013), Web sites, textbooks, and bibliographies for articles relating to trauma DC. The innovation of DC was then classified according to the Innovation, Development, Exploration, Assessment, and Long-term study model of surgical innovation. The "innovation" of DC originated from the use of therapeutic liver packing, a practice that had previously been abandoned after World War II because of adverse events. It then "developed" into abbreviated laparotomy using "rapid conservative operative techniques." Subsequent "exploration" resulted in the application of DC to increasingly complex abdominal injuries and thoracic, peripheral vascular, and orthopedic injuries. Increasing use of DC laparotomy was followed by growing reports of postinjury abdominal compartment syndrome and prophylactic use of the open abdomen to prevent intra-abdominal hypertension after DC laparotomy. By the year 2000, DC surgery had been widely adopted and was recommended for use in surgical journals, textbooks, and teaching courses ("assessment" stage of innovation). "Long-term study" of DC is raising questions about whether the procedure should be used more selectively in the context of improving resuscitation practices. The history of the innovation of DC illustrates how a previously abandoned surgical technique was adapted and readopted in response to an increased understanding of trauma patient physiology and changing injury patterns and trauma resuscitation practices.

The CSSIAR v.1.00 Software: A new tool based on SIAR to assess soil redistribution using Compound Specific Stable Isotopes

NASA Astrophysics Data System (ADS)

Sergio, de los Santos-Villalobos; Claudio, Bravo-Linares; dos Anjos Roberto, Meigikos; Renan, Cardoso; Max, Gibbs; Andrew, Swales; Lionel, Mabit; Gerd, Dercon

Soil erosion is one of the biggest challenges for food production around the world. Many techniques have been used to evaluate and mitigate soil degradation. Nowadays isotopic techniques are becoming a powerful tool to assess soil apportionment. One of the innovative techniques used is the Compound Specific Stable Isotopes (CSSI) analysis, which has been used to track down sediments and specify their sources by the isotopic signature of δ13 C in specific fatty acids. The application of this technique on soil apportionment has been recently developed, however there is a lack of user-friendly Software for data processing and interpretation. The aim of this article is to introduce a new open source tool for working with data sets generated by the use of the CSSI technique to assess soil apportionment, called the CSSIARv1.00 Software

Research and design on system of asset management based on RFID

NASA Astrophysics Data System (ADS)

Guan, Peng; Du, HuaiChang; Jing, Hua; Zhang, MengYue; Zhang, Meng; Xu, GuiXian

2011-10-01

By analyzing the problems in the current assets management, this thesis proposing RFID technology will be applied to asset management in order to improve the management level of automation and information. This paper designed the equipment identification based on 433MHz RFID tag and reader which was deeply studied on the basis of RFID tag and card reader circuits, and this paper also illustrates the system of asset management. The RS232 converts Ethernet is a innovative technology to transfer data to PC monitor software, and implement system of asset management based on WEB techniques (PHP and MySQL).

INNOVATIVE METHODS FOR EMISSION-INVENTORY DEVELOPMENT AND EVALUATION: WORKSHOP SUMMARY

EPA Science Inventory

Emission inventories are an essential tool for evaluating, managing, and regulating air pollution. Refinements and innovations in instruments that measure air pollutants, models that calculate emissions as well as techniques for data management and uncertainty assessment are nee...

Advancing Lie Detection by Inducing Cognitive Load on Liars: A Review of Relevant Theories and Techniques Guided by Lessons from Polygraph-Based Approaches

PubMed Central

Walczyk, Jeffrey J.; Igou, Frank P.; Dixon, Alexa P.; Tcholakian, Talar

2013-01-01

This article critically reviews techniques and theories relevant to the emerging field of “lie detection by inducing cognitive load selectively on liars.” To help these techniques benefit from past mistakes, we start with a summary of the polygraph-based Controlled Question Technique (CQT) and the major criticisms of it made by the National Research Council (2003), including that it not based on a validated theory and administration procedures have not been standardized. Lessons from the more successful Guilty Knowledge Test are also considered. The critical review that follows starts with the presentation of models and theories offering insights for cognitive lie detection that can undergird theoretically load-inducing approaches. This is followed by evaluation of specific research-based, load-inducing proposals, especially for their susceptibility to rehearsal and other countermeasures. To help organize these proposals and suggest new direction for innovation and refinement, a theoretical taxonomy is presented based on the type of cognitive load induced in examinees (intrinsic or extraneous) and how open-ended the responses to test items are. Finally, four recommendations are proffered that can help researchers and practitioners to avert the corresponding mistakes with the CQT and yield new, valid cognitive lie detection technologies. PMID:23378840

SOIL AND SEDIMENT SAMPLING METHODS | Science ...

EPA Pesticide Factsheets

The EPA Office of Solid Waste and Emergency Response's (OSWER) Office of Superfund Remediation and Technology Innovation (OSRTI) needs innovative methods and techniques to solve new and difficult sampling and analytical problems found at the numerous Superfund sites throughout the United States. Inadequate site characterization and a lack of knowledge of surface and subsurface contaminant distributions hinders EPA's ability to make the best decisions on remediation options and to conduct the most effective cleanup efforts. To assist OSWER, NERL conducts research to improve their capability to more accurately, precisely, and efficiently characterize Superfund, RCRA, LUST, oil spills, and brownfield sites and to improve their risk-based decision making capabilities, research is being conducted on improving soil and sediment sampling techniques and improving the sampling and handling of volatile organic compound (VOC) contaminated soils, among the many research programs and tasks being performed at ESD-LV.Under this task, improved sampling approaches and devices will be developed for characterizing the concentration of VOCs in soils. Current approaches and devices used today can lose up to 99% of the VOCs present in the sample due inherent weaknesses in the device and improper/inadequate collection techniques. This error generally causes decision makers to markedly underestimate the soil VOC concentrations and, therefore, to greatly underestimate the ecological

Privacy protection for clinical and genomic data. The use of privacy-enhancing techniques in medicine.

PubMed

Claerhout, B; DeMoor, G J E

2005-03-01

Privacy includes the right of individuals and organisations to determine for themselves when, how and to what extent information about them is communicated to others. The growing need of managing large amounts of both clinical and genetic data raises important legal and ethical challenges. This paper introduces some of the privacy-protection problems related to classical and genomic medicine, and highlights the relevance of trusted third parties and of privacy-enhancing techniques (PETs) in the context of data collection, e.g., for research. Practical approaches based on two pseudonymisation models, for both batch data collection and interactive data storage, are presented. The actual application of the described techniques today proves the possible benefits for medicine that innovative privacy-enhancing techniques can provide. Technical PET solutions can unlock valuable data sources, otherwise not available.

Space exploration initiative (SEI) logistics support lessons from the DoD

NASA Astrophysics Data System (ADS)

Cox, John R.; McCoy, Walbert G.; Jenkins, Terence

Proven and innovative logistics management approaches and techniques used for developing and supporting DoD and Strategic Defense Initiative Office (SDIO) systems are described on the basis of input from DoD to the SEI Synthesis Group; SDIO-developed logistics initiatives, innovative tools, and methodologies; and logistics planning support provided to the NASA/Johnson Planet Surface System Office. The approach is tailored for lunar/Martian surface operations, and provides guidelines for the development and management of a crucial element of the SEI logistics support program. A case study is presented which shows how incorporation of DoD's proven and innovative logistics management approach, tools, and techniques can substantially benefit early logistics planning for SEI, while also implementing many of DoD's recommendations for SEI.

Method-centered digital communities on protocols.io for fast-paced scientific innovation.

PubMed

Kindler, Lori; Stoliartchouk, Alexei; Teytelman, Leonid; Hurwitz, Bonnie L

2016-01-01

The Internet has enabled online social interaction for scientists beyond physical meetings and conferences. Yet despite these innovations in communication, dissemination of methods is often relegated to just academic publishing. Further, these methods remain static, with subsequent advances published elsewhere and unlinked. For communities undergoing fast-paced innovation, researchers need new capabilities to share, obtain feedback, and publish methods at the forefront of scientific development. For example, a renaissance in virology is now underway given the new metagenomic methods to sequence viral DNA directly from an environment. Metagenomics makes it possible to "see" natural viral communities that could not be previously studied through culturing methods. Yet, the knowledge of specialized techniques for the production and analysis of viral metagenomes remains in a subset of labs.  This problem is common to any community using and developing emerging technologies and techniques. We developed new capabilities to create virtual communities in protocols.io, an open access platform, for disseminating protocols and knowledge at the forefront of scientific development. To demonstrate these capabilities, we present a virology community forum called VERVENet. These new features allow virology researchers to share protocols and their annotations and optimizations, connect with the broader virtual community to share knowledge, job postings, conference announcements through a common online forum, and discover the current literature through personalized recommendations to promote discussion of cutting edge research. Virtual communities in protocols.io enhance a researcher's ability to: discuss and share protocols, connect with fellow community members, and learn about new and innovative research in the field.  The web-based software for developing virtual communities is free to use on protocols.io. Data are available through public APIs at protocols.io.

An engineering perspective on 3D printed personalized scaffolds for tracheal suspension technique

PubMed Central

An, Jia

2016-01-01

3D printing is a large family of many distinct technologies covering a wide range of topics. From an engineering point of view, there should be considerations for selection of design, material, and process when using 3D printing for surgical technique innovation such as personalized scaffolds. Moreover, cost should also be considered if there are equally effective alternatives to the innovation. Furthermore, engineering considerations and options should be clearly communicated and readily available to surgeons for advancement in future. PMID:28149624

An engineering perspective on 3D printed personalized scaffolds for tracheal suspension technique.

PubMed

An, Jia; Chua, Chee Kai

2016-12-01

3D printing is a large family of many distinct technologies covering a wide range of topics. From an engineering point of view, there should be considerations for selection of design, material, and process when using 3D printing for surgical technique innovation such as personalized scaffolds. Moreover, cost should also be considered if there are equally effective alternatives to the innovation. Furthermore, engineering considerations and options should be clearly communicated and readily available to surgeons for advancement in future.

Novel Variants of a Histogram Shift-Based Reversible Watermarking Technique for Medical Images to Improve Hiding Capacity

PubMed Central

Tuckley, Kushal

2017-01-01

In telemedicine systems, critical medical data is shared on a public communication channel. This increases the risk of unauthorised access to patient's information. This underlines the importance of secrecy and authentication for the medical data. This paper presents two innovative variations of classical histogram shift methods to increase the hiding capacity. The first technique divides the image into nonoverlapping blocks and embeds the watermark individually using the histogram method. The second method separates the region of interest and embeds the watermark only in the region of noninterest. This approach preserves the medical information intact. This method finds its use in critical medical cases. The high PSNR (above 45 dB) obtained for both techniques indicates imperceptibility of the approaches. Experimental results illustrate superiority of the proposed approaches when compared with other methods based on histogram shifting techniques. These techniques improve embedding capacity by 5–15% depending on the image type, without affecting the quality of the watermarked image. Both techniques also enable lossless reconstruction of the watermark and the host medical image. A higher embedding capacity makes the proposed approaches attractive for medical image watermarking applications without compromising the quality of the image. PMID:29104744

The impact of innovation intermediary on knowledge transfer

NASA Astrophysics Data System (ADS)

Lin, Min; Wei, Jun

2018-07-01

Many firms have opened up their innovation process and actively transfer knowledge with external partners in the market of technology. To reduce some of the market inefficiencies, more and more firms collaborate with innovation intermediaries. In light of the increasing importance of intermediary in the context of open innovation, we in this paper systematically investigate the effect of innovation intermediary on knowledge transfer and innovation process in networked systems. We find that the existence of innovation intermediary is conducive to the knowledge diffusion and facilitate the knowledge growth at system level. Interestingly, the scale of the innovation intermediary has little effect on the growth of knowledge. We further investigate the selection of intermediary members by comparing four selection strategies: random selection, initial knowledge level based selection, absorptive capability based selection, and innovative ability based selection. It is found that the selection strategy based on innovative ability outperforms all the other strategies in promoting the system knowledge growth. Our study provides a theoretical understanding of the impact of innovation intermediary on knowledge transfer and sheds light on the design and selection of innovation intermediary in open innovation.

Innovation in values based public health nursing student selection: A qualitative evaluation of candidate and selection panel member perspectives.

PubMed

McGraw, Caroline; Abbott, Stephen; Brook, Judy

2018-02-19

Values based recruitment emerges from the premise that a high degree of value congruence, or the extent to which an individual's values are similar to those of the health organization in which they work, leads to organizational effectiveness. The aim of this evaluation was to explore how candidates and selection panel members experienced and perceived innovative methods of values based public health nursing student selection. The evaluation was framed by a qualitative exploratory design involving semi-structured interviews and a group exercise. Data were thematically analyzed. Eight semi-structured interviews were conducted with selection panel members. Twenty-two successful candidates took part in a group exercise. The use of photo elicitation interviews and situational judgment questions in the context of selection to a university-run public health nursing educational program was explored. While candidates were ambivalent about the use of photo elicitation interviews, with some misunderstanding the task, selection panel members saw the benefits for improving candidate expression and reducing gaming and deception. Situational interview questions were endorsed by candidates and selection panel members due to their fidelity to real-life problems and the ability of panel members to discern value congruence from candidates' responses. Both techniques offered innovative solutions to candidate selection for entry to the public health nursing education program. © 2018 Wiley Periodicals, Inc.

On the Use of the Electrospinning Coating Technique to Produce Antimicrobial Polyhydroxyalkanoate Materials Containing In Situ-Stabilized Silver Nanoparticles.

PubMed

Castro-Mayorga, Jinneth Lorena; Fabra, Maria Jose; Cabedo, Luis; Lagaron, Jose Maria

2016-12-29

Electro-hydrodynamic processing, comprising electrospraying and electrospinning techniques, has emerged as a versatile technology to produce nanostructured fiber-based and particle-based materials. In this work, an antimicrobial active multilayer system comprising a commercial polyhydroxyalkanoate substrate (PHA) and an electrospun PHA coating containing in situ-stabilized silver nanoparticles (AgNPs) was successfully developed and characterized in terms of morphology, thermal, mechanical, and barrier properties. The obtained materials reduced the bacterial population of Salmonella enterica below the detection limits at very low silver loading of 0.002 ± 0.0005 wt %. As a result, this study provides an innovative route to generate fully renewable and biodegradable materials that could prevent microbial outbreaks in food packages and food contact surfaces.

On the Use of the Electrospinning Coating Technique to Produce Antimicrobial Polyhydroxyalkanoate Materials Containing In Situ-Stabilized Silver Nanoparticles

PubMed Central

Castro-Mayorga, Jinneth Lorena; Fabra, Maria Jose; Cabedo, Luis; Lagaron, Jose Maria

2016-01-01

Electro-hydrodynamic processing, comprising electrospraying and electrospinning techniques, has emerged as a versatile technology to produce nanostructured fiber-based and particle-based materials. In this work, an antimicrobial active multilayer system comprising a commercial polyhydroxyalkanoate substrate (PHA) and an electrospun PHA coating containing in situ-stabilized silver nanoparticles (AgNPs) was successfully developed and characterized in terms of morphology, thermal, mechanical, and barrier properties. The obtained materials reduced the bacterial population of Salmonella enterica below the detection limits at very low silver loading of 0.002 ± 0.0005 wt %. As a result, this study provides an innovative route to generate fully renewable and biodegradable materials that could prevent microbial outbreaks in food packages and food contact surfaces. PMID:28336838

A Survey of Techniques for Security Architecture Analysis

DTIC Science & Technology

2003-05-01

to be corrected immediately. 49 DSTO-TR-1438 A software phenomenon is the "user innovation network", examples of such networks being "free" and "open...source" software projects. These networks have innovation development, production, distribution and consumption all being performed by users/self...manufacturers. "User innovation networks can function entirely independently of manufacturers because (1) at least some users have sufficient incentive to

Innovations in Functional Neurosurgery and Anesthetic Implications.

PubMed

Dunn, Lauren K; Durieux, Marcel E; Elias, W Jeffrey; Nemergut, Edward C; Naik, Bhiken I

2018-01-01

Functional neurosurgery has undergone rapid growth over the last few years fueled by advances in imaging technology and novel treatment modalities. These advances have led to new surgical treatments using minimally invasive and precise techniques for conditions such as Parkinson's disease, essential tremor, epilepsy, and psychiatric disorders. Understanding the goals and technological issues of these procedures is imperative for the anesthesiologist to ensure safe management of patients presenting for functional neurosurgical procedures. In this review, we discuss the advances in neurosurgical techniques for deep brain stimulation, focused ultrasound and minimally invasive laser-based treatment of refractory epilepsy and provide a guideline for anesthesiologists caring for patients undergoing these procedures.

Multifrequency InSAR height reconstruction through maximum likelihood estimation of local planes parameters.

PubMed

Pascazio, Vito; Schirinzi, Gilda

2002-01-01

In this paper, a technique that is able to reconstruct highly sloped and discontinuous terrain height profiles, starting from multifrequency wrapped phase acquired by interferometric synthetic aperture radar (SAR) systems, is presented. We propose an innovative unwrapping method, based on a maximum likelihood estimation technique, which uses multifrequency independent phase data, obtained by filtering the interferometric SAR raw data pair through nonoverlapping band-pass filters, and approximating the unknown surface by means of local planes. Since the method does not exploit the phase gradient, it assures the uniqueness of the solution, even in the case of highly sloped or piecewise continuous elevation patterns with strong discontinuities.

UTILITY EXPERIENCE WITH INNOVATIVE WATER MAIN REHAB TECHNIQUES

EPA Science Inventory

All utilities are motivated to renew their aging infrastructure in the most efficient manner with respect to cost and minimal disruption to the community. American Water was given an opportunity to participate in an EPA funded project to demonstrate innovative water (and wastewa...

Innovative green technique for preparing of flame retardant cotton

USDA-ARS?s Scientific Manuscript database

Due to its environmentally benign character, microwave-assisted or supercritical carbon dioxide high pressure reactors are considered in green chemistry as a substitute for organic solvents in chemical reactions. In this paper, an innovative approach for preparation of flame retardant cotton fabric ...

System of Indicators in the Innovation Management: Business Intelligence Applied to Tourism

NASA Astrophysics Data System (ADS)

Lozada, Dayana; Araque, Francisco; Castillo, Jose Manuel; Salguero, Alberto; Delgado, Cecilia; Noda, Marcia; Hernández, Gilberto

The work presents an approach to study mechanisms that allows managers the Innovation Management (IM) measurements. It is assumed, as main motivation, the analysis of patterns for the design of an integral system of indicators. A methodology that integrates the thought process, focusing on the Business Intelligence and the Balance Scorecard will be presented. A group of indexes based on the multidimensionality of IM in organizations of the sector of tourism is proposed. To approach this quality it is necessary to contextualize, in the conditions of sectoral operation, the theories, models and systems used in our approach. It has been used intervention methods like experts' criteria, consensus search techniques by means of surveys, consultation of documents, and statistical methods such as analysis of the main components.

Defense Small Business Innovation Research Program (SBIR). Abstracts of Phase I Awards. 1986.

DTIC Science & Technology

1986-01-01

RELATIVE HUMIDITY AT TEMPERATURES FOUND IN ARCTIC ENVIRONMENTS. IT IS BASED ON THE OBSERVATION THAT CERTAIN FLUORESCENT AND PHOSPHORESCENT COMPOUNDS ...FREEDMAN TITLE: III-V COMPOUNDS TRACE ELEMENT PROFILE ANALYSIS USING LASER ASSISTED S PECTROSCOPY T 55 OFFICE: RADC/DOR A NOVEL MICROPROBE ANALYSIS...AND II-VI AND III-V COMPOUNDS . THESE ADVANTAGES MAKE THE LSCE TECHNIQUE PARTICULARY WELL SUITED TO THE DEPOSITION OF QUANTUM WELL AND SUPERLATT ICE

Nanocrystalline sp{sup 2} and sp{sup 3} carbons: CVD synthesis and applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terranova, M. L.; Rossi, M.; Tamburri, E., E-mail: emanuela.tamburri@uniroma2.it

The design and production of innovative materials based on nanocrystalline sp{sup 2}- and sp{sup 3}-coordinated carbons is presently a focus of the scientific community. We present a review of the nanostructures obtained in our labs using a series of synthetic routes, which make use of chemical vapor deposition (CVD) techniques for the selective production of non-planar graphitic nanostructures, nanocrystalline diamonds, and hybrid two-phase nanostructures.

A novel murmur-based heart sound feature extraction technique using envelope-morphological analysis

NASA Astrophysics Data System (ADS)

Yao, Hao-Dong; Ma, Jia-Li; Fu, Bin-Bin; Wang, Hai-Yang; Dong, Ming-Chui

2015-07-01

Auscultation of heart sound (HS) signals serves as an important primary approach to diagnose cardiovascular diseases (CVDs) for centuries. Confronting the intrinsic drawbacks of traditional HS auscultation, computer-aided automatic HS auscultation based on feature extraction technique has witnessed explosive development. Yet, most existing HS feature extraction methods adopt acoustic or time-frequency features which exhibit poor relationship with diagnostic information, thus restricting the performance of further interpretation and analysis. Tackling such a bottleneck problem, this paper innovatively proposes a novel murmur-based HS feature extraction method since murmurs contain massive pathological information and are regarded as the first indications of pathological occurrences of heart valves. Adapting discrete wavelet transform (DWT) and Shannon envelope, the envelope-morphological characteristics of murmurs are obtained and three features are extracted accordingly. Validated by discriminating normal HS and 5 various abnormal HS signals with extracted features, the proposed method provides an attractive candidate in automatic HS auscultation.

Raster Scan Computer Image Generation (CIG) System Based On Refresh Memory

NASA Astrophysics Data System (ADS)

Dichter, W.; Doris, K.; Conkling, C.

1982-06-01

A full color, Computer Image Generation (CIG) raster visual system has been developed which provides a high level of training sophistication by utilizing advanced semiconductor technology and innovative hardware and firmware techniques. Double buffered refresh memory and efficient algorithms eliminate the problem of conventional raster line ordering by allowing the generated image to be stored in a random fashion. Modular design techniques and simplified architecture provide significant advantages in reduced system cost, standardization of parts, and high reliability. The major system components are a general purpose computer to perform interfacing and data base functions; a geometric processor to define the instantaneous scene image; a display generator to convert the image to a video signal; an illumination control unit which provides final image processing; and a CRT monitor for display of the completed image. Additional optional enhancements include texture generators, increased edge and occultation capability, curved surface shading, and data base extensions.

Managing for Innovation in the Age of Information Technology.

ERIC Educational Resources Information Center

Downes, Robin N.

1987-01-01

Discusses the need for innovative management techniques if integrated library systems are to be implemented successfully, as well as the opportunity the installation process provides to reexamine the organizational structure and objectives of the library and to introduce a creative organizational environment. (CLB)

A review of extra-articular prosthetic stabilization of the cranial cruciate ligament-deficient stifle.

PubMed

Tonks, C A; Lewis, D D; Pozzi, A

2011-01-01

Extra-articular prosthetic stabilization techniques have been used as a method of stabilization of the cranial cruciate ligament (CrCL)-deficient stifle for decades. During extra-articular prosthetic stabilization, the prosthesis is anchored to the femur and tibia, and tensioned in the attempt to resolve femorotibial instability. The position of the anchor points of the prosthesis is crucial for restoring a normal range of joint motion and mitigating alterations in prosthesis tension during motion. Recently developed techniques offer several innovations with potential advantages such as bone-to-bone fixation, prosthetic materials with better mechanical properties, and improved isometry of the anchor points. Whether these innovations provide clinically superior results to the traditional techniques such as lateral circumfabellar-tibial suture techniques has yet to be determined.

Loop mediated isothermal amplification: An innovative gene amplification technique for animal diseases.

PubMed

Sahoo, Pravas Ranjan; Sethy, Kamadev; Mohapatra, Swagat; Panda, Debasis

2016-05-01

India being a developing country mainly depends on livestock sector for its economy. However, nowadays, there is emergence and reemergence of more transboundary animal diseases. The existing diagnostic techniques are not so quick and with less specificity. To reduce the economy loss, there should be a development of rapid, reliable, robust diagnostic technique, which can work with high degree of sensitivity and specificity. Loop mediated isothermal amplification assay is a rapid gene amplification technique that amplifies nucleic acid under an isothermal condition with a set of designed primers spanning eight distinct sequences of the target. This assay can be used as an emerging powerful, innovative gene amplification diagnostic tool against various pathogens of livestock diseases. This review is to highlight the basic concept and methodology of this assay in livestock disease.

An innovative application of time-domain spectroscopy on localized surface plasmon resonance sensing

NASA Astrophysics Data System (ADS)

Li, Meng-Chi; Chang, Ying-Feng; Wang, Huai-Yi; Lin, Yu-Xen; Kuo, Chien-Cheng; Annie Ho, Ja-An; Lee, Cheng-Chung; Su, Li-Chen

2017-03-01

White-light scanning interferometry (WLSI) is often used to study the surface profiles and properties of thin films because the strength of the technique lies in its ability to provide fast and high resolution measurements. An innovative attempt is made in this paper to apply WLSI as a time-domain spectroscopic system for localized surface plasmon resonance (LSPR) sensing. A WLSI-based spectrometer is constructed with a breadboard of WLSI in combination with a spectral centroid algorithm for noise reduction and performance improvement. Experimentally, the WLSI-based spectrometer exhibits a limit of detection (LOD) of 1.2 × 10-3 refractive index units (RIU), which is better than that obtained with a conventional UV-Vis spectrometer, by resolving the LSPR peak shift. Finally, the bio-applicability of the proposed spectrometer was investigated using the rs242557 tau gene, an Alzheimer’s and Parkinson’s disease biomarker. The LOD was calculated as 15 pM. These results demonstrate that the proposed WLSI-based spectrometer could become a sensitive time-domain spectroscopic biosensing platform.

Innovations in Radiotherapy Technology.

PubMed

Feain, I J; Court, L; Palta, J R; Beddar, S; Keall, P

2017-02-01

Many low- and middle-income countries, together with remote and low socioeconomic populations within high-income countries, lack the resources and services to deal with cancer. The challenges in upgrading or introducing the necessary services are enormous, from screening and diagnosis to radiotherapy planning/treatment and quality assurance. There are severe shortages not only in equipment, but also in the capacity to train, recruit and retain staff as well as in their ongoing professional development via effective international peer-review and collaboration. Here we describe some examples of emerging technology innovations based on real-time software and cloud-based capabilities that have the potential to redress some of these areas. These include: (i) automatic treatment planning to reduce physics staffing shortages, (ii) real-time image-guided adaptive radiotherapy technologies, (iii) fixed-beam radiotherapy treatment units that use patient (rather than gantry) rotation to reduce infrastructure costs and staff-to-patient ratios, (iv) cloud-based infrastructure programmes to facilitate international collaboration and quality assurance and (v) high dose rate mobile cobalt brachytherapy techniques for intraoperative radiotherapy. Copyright © 2016 The Royal College of Radiologists. All rights reserved.

Evolution and revolution: gauging the impact of technological and technical innovation on Olympic performance.

PubMed

Balmer, Nigel; Pleasence, Pascoe; Nevill, Alan

2012-01-01

A number of studies have pointed to a plateauing of athletic performance, with the suggestion that further improvements will need to be driven by revolutions in technology or technique. In the present study, we examine post-war men's Olympic performance in jumping events (pole vault, long jump, high jump, triple jump) to determine whether performance has indeed plateaued and to present techniques, derived from models of human growth, for assessing the impact of technological and technical innovation over time (logistic and double logistic models of growth). Significantly, two of the events involve well-documented changes in technology (pole material in pole vault) or technique (the Fosbury Flop in high jump), while the other two do not. We find that in all four cases, performance appears to have plateaued and that no further "general" improvement should be expected. In the case of high jump, the double logistic model provides a convenient method for modelling and quantifying a performance intervention (in this case the Fosbury Flop). However, some shortcomings are revealed for pole vault, where evolutionary post-war improvements and innovation (fibre glass poles) were concurrent, preventing their separate identification in the model. In all four events, it is argued that further general growth in performance will indeed need to rely predominantly on technological or technical innovation.

Technological innovations in the development of cardiovascular clinical information systems.

PubMed

Hsieh, Nan-Chen; Chang, Chung-Yi; Lee, Kuo-Chen; Chen, Jeen-Chen; Chan, Chien-Hui

2012-04-01

Recent studies have shown that computerized clinical case management and decision support systems can be used to assist surgeons in the diagnosis of disease, optimize surgical operation, aid in drug therapy and decrease the cost of medical treatment. Therefore, medical informatics has become an extensive field of research and many of these approaches have demonstrated potential value for improving medical quality. The aim of this study was to develop a web-based cardiovascular clinical information system (CIS) based on innovative techniques, such as electronic medical records, electronic registries and automatic feature surveillance schemes, to provide effective tools and support for clinical care, decision-making, biomedical research and training activities. The CIS developed for this study contained monitoring, surveillance and model construction functions. The monitoring layer function provided a visual user interface. At the surveillance and model construction layers, we explored the application of model construction and intelligent prognosis to aid in making preoperative and postoperative predictions. With the use of the CIS, surgeons can provide reasonable conclusions and explanations in uncertain environments.

The potential of Internet of m-health Things "m-IoT" for non-invasive glucose level sensing.

PubMed

Istepanian, R S H; Hu, S; Philip, N Y; Sungoor, A

2011-01-01

An amalgamated concept of Internet of m-health Things (m-IoT) has been introduced recently and defined as a new concept that matches the functionalities of m-health and IoT for a new and innovative future (4G health) applications. It is well know that diabetes is a major chronic disease problem worldwide with major economic and social impact. To-date there have not been any studies that address the potential of m-IoT for non-invasive glucose level sensing with advanced opto-physiological assessment technique and diabetes management. In this paper we address the potential benefits of using m-IoT in non-invasive glucose level sensing and the potential m-IoT based architecture for diabetes management. We expect to achieve intelligent identification and management in a heterogeneous connectivity environment from the mobile healthcare perspective. Furthermore this technology will enable new communication connectivity routes between mobile patients and care services through innovative IP based networking architectures.

KNMI DataLab experiences in serving data-driven innovations

NASA Astrophysics Data System (ADS)

Noteboom, Jan Willem; Sluiter, Raymond

2016-04-01

Climate change research and innovations in weather forecasting rely more and more on (Big) data. Besides increasing data from traditional sources (such as observation networks, radars and satellites), the use of open data, crowd sourced data and the Internet of Things (IoT) is emerging. To deploy these sources of data optimally in our services and products, KNMI has established a DataLab to serve data-driven innovations in collaboration with public and private sector partners. Big data management, data integration, data analytics including machine learning and data visualization techniques are playing an important role in the DataLab. Cross-domain data-driven innovations that arise from public-private collaborative projects and research programmes can be explored, experimented and/or piloted by the KNMI DataLab. Furthermore, advice can be requested on (Big) data techniques and data sources. In support of collaborative (Big) data science activities, scalable environments are offered with facilities for data integration, data analysis and visualization. In addition, Data Science expertise is provided directly or from a pool of internal and external experts. At the EGU conference, gained experiences and best practices are presented in operating the KNMI DataLab to serve data-driven innovations for weather and climate applications optimally.

Overcoming Codes and Standards Barriers to Innovations in Building Energy Efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, Pamala C.; Gilbride, Theresa L.

2015-02-15

In this journal article, the authors discuss approaches to overcoming building code barriers to energy-efficiency innovations in home construction. Building codes have been a highly motivational force for increasing the energy efficiency of new homes in the United States in recent years. But as quickly as the codes seem to be changing, new products are coming to the market at an even more rapid pace, sometimes offering approaches and construction techniques unthought of when the current code was first proposed, which might have been several years before its adoption by various jurisdictions. Due to this delay, the codes themselves canmore » become barriers to innovations that might otherwise be helping to further increase the efficiency, comfort, health or durability of new homes. . The U.S. Department of Energy’s Building America, a program dedicated to improving the energy efficiency of America’s housing stock through research and education, is working with the U.S. housing industry through its research teams to help builders identify and remove code barriers to innovation in the home construction industry. The article addresses several approaches that builders use to achieve approval for innovative building techniques when code barriers appear to exist.« less

ERATOSTHENES: excellence research Centre for Earth surveillance and space-based monitoring of the environment, the EXCELSIOR Horizon 2020 teaming project

NASA Astrophysics Data System (ADS)

Hadjimitsis, Diofantos G.; Kontoes, Haris; Schreier, Gunter; Ansmann, Albert; Komodromos, George; Themistocleous, Kyriacos; Mamouri, Rodanthi; Michaelides, Silas; Nisantzi, Argyro; Papoutsa, Christiana; Neocleous, Kyriacos; Mettas, Christodoulos; Tzouvaras, Marios; Evagorou, Evagoras; Christofe, Andreas; Melillos, George; Papoutsis, Ioannis

2017-10-01

The aim of this paper is to present the strategy and vision to upgrade the existing ERATOSTHENES Research Centre (ERC) established within the Cyprus University of Technology (CUT) into a sustainable, viable and autonomous Centre of Excellence (CoE) for Earth Surveillance and Space-Based Monitoring of the Environment, which will provide the highest quality of related services on the National, European and International levels. EXCELSIOR is a Horizon 2020 Teaming project which addresses a specific challenge defined by the work program, namely, the reduction of substantial disparities in the European Union by supporting research and innovation activities and systems in low performing countries. It also aims at establishing long-term and strategic partnerships between the Teaming partners, thus reducing internal research and innovation disparities within European Research and Innovation landscape. The proposed CoE envisions the upgrading of the existing ERC into an inspiring environment for conducting basic and applied research and innovation in the areas of the integrated use of remote sensing and space-based techniques for monitoring the environment. Environment has been recognized by the Smart Specialization Strategy of Cyprus as the first horizontal priority for future growth of the island. The foreseen upgrade will regard the expansion of this vision to systematic monitoring of the environment using Earth Observation, space and ground based integrated technologies. Such an approach will lead to the systematic monitoring of all three domains of the Environment (Air, Land, Water). Five partners have united to upgrade the existing ERC into a CoE, with the common vision to become a world-class innovation, research and education centre, actively contributing to the European Research Area (ERA). More specifically, the Teaming project is a team effort between the Cyprus University of Technology (CUT, acting as the coordinator), the German Aerospace Centre (DLR), the National Observatory of Athens (NOA), the German Leibniz Institute for Tropospheric Research (TROPOS) and the Cyprus Department of Electronic Communications of the Ministry of Transport, Communications and Works (DEC-MTCW).

Propulsion simulation for magnetically suspended wind tunnel models

NASA Technical Reports Server (NTRS)

Joshi, Prakash B.; Beerman, Henry P.; Chen, James; Krech, Robert H.; Lintz, Andrew L.; Rosen, David I.

1990-01-01

The feasibility of simulating propulsion-induced aerodynamic effects on scaled aircraft models in wind tunnels employing Magnetic Suspension and Balance Systems. The investigation concerned itself with techniques of generating exhaust jets of appropriate characteristics. The objectives were to: (1) define thrust and mass flow requirements of jets; (2) evaluate techniques for generating propulsive gas within volume limitations imposed by magnetically-suspended models; (3) conduct simple diagnostic experiments for techniques involving new concepts; and (4) recommend experiments for demonstration of propulsion simulation techniques. Various techniques of generating exhaust jets of appropriate characteristics were evaluated on scaled aircraft models in wind tunnels with MSBS. Four concepts of remotely-operated propulsion simulators were examined. Three conceptual designs involving innovative adaptation of convenient technologies (compressed gas cylinders, liquid, and solid propellants) were developed. The fourth innovative concept, namely, the laser-assisted thruster, which can potentially simulate both inlet and exhaust flows, was found to require very high power levels for small thrust levels.

Headspace techniques in foods, fragrances and flavors: an overview.

PubMed

Rouseff, R; Cadwallader, K

2001-01-01

Headspace techniques have traditionally involved the collection of volatiles in the vapor state under either dynamic or static conditions as a means of determining concentrations in the product of interest. A brief overview of contemporary headspace applications and recent innovations are presented from the literature and Chapters in this book. New approaches used to concentrate volatiles under static conditions such as solid phase micro extraction, SPME, are examined. Advances in purge and trap applications and automation are also presented. Innovative methods of evaluating headspace volatiles using solid state sensor arrays (electronic noses) or mass spectrometers without prior separation are referenced. Numerous food and beverage headspace techniques are also reviewed. Advantages, limitations and alternatives to headspace analysis are presented.

An Innovative Solution to NASA's NEO Impact Threat Mitigation Grand Challenge and Flight Validation Mission Architecture Development

NASA Technical Reports Server (NTRS)

Wie, Bong; Barbee, Brent; Pitz, Alan; Kaplinger, Brian; Hawkins, Matt; Winkler, Tim; Premaratne, Pavithra; Vardaxis, George; Lyzhoft, Joshua; Zimmerman, Ben

2015-01-01

To develop an innovative yet practically implementable mitigation technique for the most probable impact threat of an asteroid or comet with short warning time(i.e., when we don't have sufficient warning times for a deflection mission)

Network analysis of surgical innovation: Measuring value and the virality of diffusion in robotic surgery.

PubMed

Garas, George; Cingolani, Isabella; Panzarasa, Pietro; Darzi, Ara; Athanasiou, Thanos

2017-01-01

Existing surgical innovation frameworks suffer from a unifying limitation, their qualitative nature. A rigorous approach to measuring surgical innovation is needed that extends beyond detecting simply publication, citation, and patent counts and instead uncovers an implementation-based value from the structure of the entire adoption cascades produced over time by diffusion processes. Based on the principles of evidence-based medicine and existing surgical regulatory frameworks, the surgical innovation funnel is described. This illustrates the different stages through which innovation in surgery typically progresses. The aim is to propose a novel and quantitative network-based framework that will permit modeling and visualizing innovation diffusion cascades in surgery and measuring virality and value of innovations. Network analysis of constructed citation networks of all articles concerned with robotic surgery (n = 13,240, Scopus®) was performed (1974-2014). The virality of each cascade was measured as was innovation value (measured by the innovation index) derived from the evidence-based stage occupied by the corresponding seed article in the surgical innovation funnel. The network-based surgical innovation metrics were also validated against real world big data (National Inpatient Sample-NIS®). Rankings of surgical innovation across specialties by cascade size and structural virality (structural depth and width) were found to correlate closely with the ranking by innovation value (Spearman's rank correlation coefficient = 0.758 (p = 0.01), 0.782 (p = 0.008), 0.624 (p = 0.05), respectively) which in turn matches the ranking based on real world big data from the NIS® (Spearman's coefficient = 0.673;p = 0.033). Network analysis offers unique new opportunities for understanding, modeling and measuring surgical innovation, and ultimately for assessing and comparing generative value between different specialties. The novel surgical innovation metrics developed may prove valuable especially in guiding policy makers, funding bodies, surgeons, and healthcare providers in the current climate of competing national priorities for investment.

Network analysis of surgical innovation: Measuring value and the virality of diffusion in robotic surgery

PubMed Central

Cingolani, Isabella; Panzarasa, Pietro; Darzi, Ara; Athanasiou, Thanos

2017-01-01

Background Existing surgical innovation frameworks suffer from a unifying limitation, their qualitative nature. A rigorous approach to measuring surgical innovation is needed that extends beyond detecting simply publication, citation, and patent counts and instead uncovers an implementation-based value from the structure of the entire adoption cascades produced over time by diffusion processes. Based on the principles of evidence-based medicine and existing surgical regulatory frameworks, the surgical innovation funnel is described. This illustrates the different stages through which innovation in surgery typically progresses. The aim is to propose a novel and quantitative network-based framework that will permit modeling and visualizing innovation diffusion cascades in surgery and measuring virality and value of innovations. Materials and methods Network analysis of constructed citation networks of all articles concerned with robotic surgery (n = 13,240, Scopus®) was performed (1974–2014). The virality of each cascade was measured as was innovation value (measured by the innovation index) derived from the evidence-based stage occupied by the corresponding seed article in the surgical innovation funnel. The network-based surgical innovation metrics were also validated against real world big data (National Inpatient Sample–NIS®). Results Rankings of surgical innovation across specialties by cascade size and structural virality (structural depth and width) were found to correlate closely with the ranking by innovation value (Spearman’s rank correlation coefficient = 0.758 (p = 0.01), 0.782 (p = 0.008), 0.624 (p = 0.05), respectively) which in turn matches the ranking based on real world big data from the NIS® (Spearman’s coefficient = 0.673;p = 0.033). Conclusion Network analysis offers unique new opportunities for understanding, modeling and measuring surgical innovation, and ultimately for assessing and comparing generative value between different specialties. The novel surgical innovation metrics developed may prove valuable especially in guiding policy makers, funding bodies, surgeons, and healthcare providers in the current climate of competing national priorities for investment. PMID:28841648

Fiber-Optic Surface Temperature Sensor Based on Modal Interference.

PubMed

Musin, Frédéric; Mégret, Patrice; Wuilpart, Marc

2016-07-28

Spatially-integrated surface temperature sensing is highly useful when it comes to controlling processes, detecting hazardous conditions or monitoring the health and safety of equipment and people. Fiber-optic sensing based on modal interference has shown great sensitivity to temperature variation, by means of cost-effective image-processing of few-mode interference patterns. New developments in the field of sensor configuration, as described in this paper, include an innovative cooling and heating phase discrimination functionality and more precise measurements, based entirely on the image processing of interference patterns. The proposed technique was applied to the measurement of the integrated surface temperature of a hollow cylinder and compared with a conventional measurement system, consisting of an infrared camera and precision temperature probe. As a result, the optical technique is in line with the reference system. Compared with conventional surface temperature probes, the optical technique has the following advantages: low heat capacity temperature measurement errors, easier spatial deployment, and replacement of multiple angle infrared camera shooting and the continuous monitoring of surfaces that are not visually accessible.

Vapor-phase deposition of polymers as a simple and versatile technique to generate paper-based microfluidic platforms for bioassay applications.

PubMed

Demirel, Gokhan; Babur, Esra

2014-05-21

Given their simplicity and functionality, paper-based microfluidic systems are considered to be ideal and promising bioassay platforms for use in less developed countries or in point-of-care services. Although a series of innovative techniques have recently been demonstrated for the fabrication of such platforms, development of simple, inexpensive and versatile new strategies are still needed in order to reach their full potential. In this communication, we describe a simple yet facile approach to fabricate paper-based sensor platforms with a desired design through a vapor-phase polymer deposition technique. We also show that the fabricated platforms could be readily employed for the detection of various biological target molecules including glucose, protein, ALP, ALT, and uric acid. The limit of detection for each target molecule was calculated to be 25 mg dL(-1) for glucose, 1.04 g L(-1) for protein, 7.81 unit per L for ALP, 1.6 nmol L(-1) for ALT, and 0.13 mmol L(-1) for uric acid.

Plastic Cubesat: An innovative and low-cost way to perform applied space research and hands-on education

NASA Astrophysics Data System (ADS)

Piattoni, Jacopo; Candini, Gian Paolo; Pezzi, Giulio; Santoni, Fabio; Piergentili, Fabrizio

2012-12-01

This paper describes the design and the manufacturing of a Cubesat platform based on a plastic structure. The Cubesat structure has been realized in plastic material (ABS) using a "rapid prototyping" technique. The "rapid prototyping" technique has several advantages including fast implementation, accuracy in manufacturing small parts and low cost. Moreover, concerning the construction of a small satellite, this technique is very useful thanks to the accuracy achievable in details, which are sometimes difficult and expensive to realize with the use of tools machine. The structure must be able to withstand the launch loads. For this reason, several simulations using an FEM simulation and an intensive vibration test campaign have been performed in the system development and test phase. To demonstrate that this structure is suitable for hosting a complete satellite system, offering innovative integrated solutions, other subsystems have been developed and assembled. Despite its small size, this single unit (1U) Cubesat has a system for active attitude control, a redundant telecommunication system, a payload camera and a photovoltaic system based on high efficiency solar cells. The developed communication subsystem has small dimensions, low power consumption and low cost. An example of the innovations introduced is the antenna system, which has been manufactured inside the ABS structure. The communication protocol which has been implemented, the AX.25 protocol, is mainly used by radio amateurs. The communication system has the capability to transmit both telemetry and data from the payload, in this case a microcamera. The attitude control subsystem is based on an active magnetic system with magnetorquers for detumbling and momentum dumping and three reaction wheels for fine control. It has a total dimension of about 50×50×50 mm. A microcontroller implements the detumbling control law autonomously taking data from integrated magnetometers and executes pointing maneuvers on the basis of commands received in real time from ground. The subsystems developed for this Cubesat have also been designed to be scaled up for larger satellites such as 2U or 3U Cubesats. The additional volume can be used for more complex payloads. Thus the satellite can be used as a low cost platform for companies, institutions or universities to test components in space.

Community-Based Participatory Research-Speed Dating: An Innovative Model for Fostering Collaborations Between Community Leaders and Academic Researchers.

PubMed

Tucker, Melanie T; Lewis, Dwight W; Payne Foster, Pamela; Lucky, Felecia; Yerby, Lea G; Hites, Lisle; Higginbotham, John C

2016-11-01

Developing meaningful community-based participatory relationships between researchers and the community can be challenging. The overall success of a community-based participatory relationship should be predicated on commitment and respect from empowered stakeholders. Prior to developing the technique discussed in this article, we hypothesized that the process of fostering relationships between researchers and the community was much like a social relationship: It has to develop organically and cannot be forced. To address this challenge, we developed a community-based participatory research-speed dating technique to foster relationships based on common interests, which we call CBPR-SD. This article describes the logistics of implementing CBPR-SD to foster scholarly collaborations. As part of a federally funded community-based research project, the speed dating technique was implemented for 10 researchers and 11 community leaders with a goal of developing scholarly collaborative groups who will submit applications for community-based research grants. In the end, four collaborative groups developed through CBPR-SD, three (75%) successfully submitted grant applications to fund pilot studies addressing obesity-related disparities in rural communities. Our preliminary findings suggest that CBPR-SD is a successful tool for promoting productive scholarly relationships between researchers and community leaders. © 2016 Society for Public Health Education.

Breaking the GaN material limits with nanoscale vertical polarisation super junction structures: A simulation analysis

NASA Astrophysics Data System (ADS)

Unni, Vineet; Sankara Narayanan, E. M.

2017-04-01

This is the first report on the numerical analysis of the performance of nanoscale vertical superjunction structures based on impurity doping and an innovative approach that utilizes the polarisation properties inherent in III-V nitride semiconductors. Such nanoscale vertical polarisation super junction structures can be realized by employing a combination of epitaxial growth along the non-polar crystallographic axes of Wurtzite GaN and nanolithography-based processing techniques. Detailed numerical simulations clearly highlight the limitations of a doping based approach and the advantages of the proposed solution for breaking the unipolar one-dimensional material limits of GaN by orders of magnitude.

Versatile light-emitting-diode-based spectral response measurement system for photovoltaic device characterization.

PubMed

Hamadani, Behrang H; Roller, John; Dougherty, Brian; Yoon, Howard W

2012-07-01

An absolute differential spectral response measurement system for solar cells is presented. The system couples an array of light emitting diodes with an optical waveguide to provide large area illumination. Two unique yet complementary measurement methods were developed and tested with the same measurement apparatus. Good agreement was observed between the two methods based on testing of a variety of solar cells. The first method is a lock-in technique that can be performed over a broad pulse frequency range. The second method is based on synchronous multifrequency optical excitation and electrical detection. An innovative scheme for providing light bias during each measurement method is discussed.

Improved ground-based remote-sensing systems help monitor plant response to climate and other changes

USGS Publications Warehouse

Dye, Dennis G.; Bogle, Rian

2016-05-26

Scientists at the U.S. Geological Survey are improving and developing new ground-based remote-sensing instruments and techniques to study how Earth’s vegetation responds to changing climates. Do seasonal grasslands and forests “green up” early (or late) and grow more (or less) during unusually warm years? How do changes in temperature and precipitation affect these patterns? Innovations in ground-based remote-sensing instrumentation can help us understand, assess, and mitigate the effects of climate change on vegetation and related land resources.

Two-step tomographic reconstructions of temperature and species concentration in a flame based on laser absorption measurements with a rotation platform

NASA Astrophysics Data System (ADS)

Xia, Huihui; Kan, Ruifeng; Xu, Zhenyu; He, Yabai; Liu, Jianguo; Chen, Bing; Yang, Chenguang; Yao, Lu; Wei, Min; Zhang, Guangle

2017-03-01

We present a system for accurate tomographic reconstruction of the combustion temperature and H2O vapor concentration of a flame based on laser absorption measurements, in combination with an innovative two-step algebraic reconstruction technique. A total of 11 collimated laser beams generated from outputs of fiber-coupled diode lasers formed a two-dimensional 5 × 6 orthogonal beam grids and measured at two H2O absorption transitions (7154.354/7154.353 cm-1 and 7467.769 cm-1). The measurement system was designed on a rotation platform to achieve a two-folder improvement in spatial resolution. Numerical simulation showed that the proposed two-step algebraic reconstruction technique for temperature and concentration, respectively, greatly improved the reconstruction accuracy of species concentration when compared with a traditional calculation. Experimental results demonstrated the good performances of the measurement system and the two-step reconstruction technique for applications such as flame monitoring and combustion diagnosis.

Evaluation of architectures for an ASP MPEG-4 decoder using a system-level design methodology

NASA Astrophysics Data System (ADS)

Garcia, Luz; Reyes, Victor; Barreto, Dacil; Marrero, Gustavo; Bautista, Tomas; Nunez, Antonio

2005-06-01

Trends in multimedia consumer electronics, digital video and audio, aim to reach users through low-cost mobile devices connected to data broadcasting networks with limited bandwidth. An emergent broadcasting network is the digital audio broadcasting network (DAB) which provides CD quality audio transmission together with robustness and efficiency techniques to allow good quality reception in motion conditions. This paper focuses on the system-level evaluation of different architectural options to allow low bandwidth digital video reception over DAB, based on video compression techniques. Profiling and design space exploration techniques are applied over the ASP MPEG-4 decoder in order to find out the best HW/SW partition given the application and platform constraints. An innovative SystemC-based system-level design tool, called CASSE, is being used for modelling, exploration and evaluation of different ASP MPEG-4 decoder HW/SW partitions. System-level trade offs and quantitative data derived from this analysis are also presented in this work.

Innovation Abstracts, Volume XV, 1993.

ERIC Educational Resources Information Center

Roueche, Suanne D., Ed.

1993-01-01

This volume of 30 one- to two-page abstracts from 1993 highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) role-playing to encourage critical thinking; (2) team learning techniques to cultivate business skills; (3) librarian-instructor partnerships to create…

Realistic Approach to Innovation.

ERIC Educational Resources Information Center

Dawson, Garth C.

Part of the Omaha police in-service training program was devoted to innovative approaches to solving police department problems and improving community relations. The sessions were an attempt to use the brainstorming technique to elicit new solutions to everyday problems faced by the rank-and-file members of the police department. The report…

Diffusion of Innovation: A Plea for Indigenous Models

ERIC Educational Resources Information Center

Rubdy, Rani

2008-01-01

Much of curriculum innovation in English language teaching in the context of former colonial countries has been derivative rather than generative, imitative rather than self-initiated or self-regulatory. This trend is in part the result of historical exigencies that made the importation of ELT approaches, methods, and techniques for classroom…

Speeding Products to Market: Waiting Time to First Product Introduction in New Firms.

ERIC Educational Resources Information Center

Schoonhoven, Claudia Bird; And Others

1990-01-01

Using event-history analysis techniques, a longitudinal study of the semiconductor industry found that substantial technological innovation lengthens development times and reduces the speed with which first products reach the marketplace. Organizations that undertook lower levels of technological innovation had relatively lower monthly…

Language and Related Approaches to the Writing Process.

ERIC Educational Resources Information Center

Seesholtz, Melvin C.

Providing instruction in language theory is an innovative technique for use in remedial and other composition courses in the two-year college. Such innovations provide intellectually stimulating material to students who lose interest when confronted with traditional grammar and composition. Students are acquainted with American Edited English in…

Strategies for Teaching Brainstorming in Design Education

ERIC Educational Resources Information Center

Mentzer, Nathan; Farrington, Shawn; Tennenhouse, Jason

2015-01-01

Innovation has been an important aspect of economic and scientific success in the United States for decades. Hobday, Coffey, Saalfeld, and Colwell (2011) suggested that, in order to produce innovative ideas, one must have a design-thinking mentality. This article provides the readers with an example of brainstorming techniques that have been…

Managerial Innovation: Rules for Successful Implementation.

ERIC Educational Resources Information Center

Baldridge, J. Victor

1980-01-01

The Higher Education Research Institute studied the impact of Exxon Foundation grants from the Resource Allocation and Management Program (RAMP) at 49 private colleges to determine if and how college planning and financial stability were affected by changes in management techniques. Rules for supporting innovations at various phases of a project's…

Particle Swarm Imaging (PSIM) - Innovative Gamma-Ray Assay - 13497

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parvin, Daniel; Clarke, Sean; Humes, Sarah J.

2013-07-01

Particle Swarm Imaging is an innovative technique used to perform quantitative gamma-ray assay. The innovation overcomes some of the difficulties associated with the accurate measurement and declaration of measurement uncertainties of radionuclide inventories within waste items when the distribution of activity is unknown. Implementation requires minimal equipment, with field measurements and results obtained using only a single electrically cooled HRGS gamma-ray detector. Examples of its application in the field are given in this paper. (authors)

Uptake of an innovation in surgery: observations from the cluster-randomized Quality Initiative in Rectal Cancer trial.

PubMed

Simunovic, Marko; Coates, Angela; Smith, Andrew; Thabane, Lehana; Goldsmith, Charles H; Levine, Mark N

2013-12-01

Theory suggests the uptake of a medical innovation is influenced by how potential adopters perceive innovation characteristics and by characteristics of potential adopters. Innovation adoption is slow among the first 20% of individuals in a target group and then accelerates. The Quality Initiative in Rectal Cancer (QIRC) trial assessed if rectal cancer surgery outcomes could be improved through surgeon participation in the QIRC strategy. We tested if traditional uptake of innovation concepts applied to surgeons in the experimental arm of the trial. The QIRC strategy included workshops, access to opinion leaders, intraoperative demonstrations, postoperative questionnaires, and audit and feedback. For intraoperative demonstrations, a participating surgeon invited an outside surgeon to demonstrate optimal rectal surgery techniques. We used surgeon timing in a demonstration to differentiate early and late adopters of the QIRC strategy. Surgeons completed surveys on perceptions of the strategy and personal characteristics. Nineteen of 56 surgeons (34%) requested an operative demonstration on their first case of rectal surgery. Early and late adopters had similar perceptions of the QIRC strategy and similar characteristics. Late adopters were less likely than early adopters to perceive an advantage for the surgical techniques promoted by the trial (p = 0.023). Most traditional diffusion of innovation concepts did not apply to surgeons in the QIRC trial, with the exception of the importance of perceptions of comparative advantage.

[Innovative therapeutic strategies for intravesical drug administration].

PubMed

Moch, C; Salmon, D; Rome, P; Marginean, R; Pivot, C; Colombel, M; Pirot, F

2013-05-01

Perspectives for innovative pharmaceutical molecules and intravesical administration of pharmacological agents are presented in the present review carried out from a recent literature. This review of the literature was built by using the PubMed and ScienceDirect databases running 20keywords revealing 34publications between 1983 and 2012. The number of referenced articles on ScienceDirect has increased in recent years, highlighting the interest of scientists for intravesical drug administration and the relevance of innovating drug delivery systems. Different modalities of intravesical administration using physical (e.g., iontophoresis, electroporation) or chemical techniques (e.g., enzyme, solvent, nanoparticles, liposomes, hydrogels) based on novel formulation methods are reported. Finally, the development of biopharmaceuticals (e.g., bacillus Calmette-Guérin, interferon α) and gene therapies is also presented and analyzed in this review. The present review exhibits new development in the pipeline for emerging intravesical drug administration strategies. Knowledge of all these therapies allows practitioners to propose a specific and tailored treatment to each patient with limiting systemic side effects. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Biomolecule-embedded metal-organic frameworks as an innovative sensing platform.

PubMed

Kempahanumakkagari, Sureshkumar; Kumar, Vanish; Samaddar, Pallabi; Kumar, Pawan; Ramakrishnappa, Thippeswamy; Kim, Ki-Hyun

Technological advancements combined with materials research have led to the generation of enormous types of novel substrates and materials for use in various biological/medical, energy, and environmental applications. Lately, the embedding of biomolecules in novel and/or advanced materials (e.g., metal-organic frameworks (MOFs), nanoparticles, hydrogels, graphene, and their hybrid composites) has become a vital research area in the construction of an innovative platform for various applications including sensors (or biosensors), biofuel cells, and bioelectronic devices. Due to the intriguing properties of MOFs (e.g., framework architecture, topology, and optical properties), they have contributed considerably to recent progresses in enzymatic catalysis, antibody-antigen interactions, or many other related approaches. Here, we aim to describe the different strategies for the design and synthesis of diverse biomolecule-embedded MOFs for various sensing (e.g., optical, electrochemical, biological, and miscellaneous) techniques. Additionally, the benefits and future prospective of MOFs-based biomolecular immobilization as an innovative sensing platform are discussed along with the evaluation on their performance to seek for further development in this emerging research area. Copyright © 2018. Published by Elsevier Inc.

Developing a validation for environmental sustainability

NASA Astrophysics Data System (ADS)

Adewale, Bamgbade Jibril; Mohammed, Kamaruddeen Ahmed; Nawi, Mohd Nasrun Mohd; Aziz, Zulkifli

2016-08-01

One of the agendas for addressing environmental protection in construction is to reduce impacts and make the construction activities more sustainable. This important consideration has generated several research interests within the construction industry, especially considering the construction damaging effects on the ecosystem, such as various forms of environmental pollution, resource depletion and biodiversity loss on a global scale. Using Partial Least Squares-Structural Equation Modeling technique, this study validates environmental sustainability (ES) construct in the context of large construction firms in Malaysia. A cross-sectional survey was carried out where data was collected from Malaysian large construction firms using a structured questionnaire. Results of this study revealed that business innovativeness and new technology are important in determining environmental sustainability (ES) of the Malaysian construction firms. It also established an adequate level of internal consistency reliability, convergent validity and discriminant validity for each of this study's constructs. And based on this result, it could be suggested that the indicators for organisational innovativeness dimensions (business innovativeness and new technology) are useful to measure these constructs in order to study construction firms' tendency to adopt environmental sustainability (ES) in their project execution.

Computer-Enhanced Visual Learning Method: A Paradigm to Teach and Document Surgical Skills

PubMed Central

Maizels, Max; Mickelson, Jennie; Yerkes, Elizabeth; Maizels, Evelyn; Stork, Rachel; Young, Christine; Corcoran, Julia; Holl, Jane; Kaplan, William E.

2009-01-01

Innovation Changes in health care are stimulating residency training programs to develop new methods for teaching surgical skills. We developed Computer-Enhanced Visual Learning (CEVL) as an innovative Internet-based learning and assessment tool. The CEVL method uses the educational procedures of deliberate practice and performance to teach and learn surgery in a stylized manner. Aim of Innovation CEVL is a learning and assessment tool that can provide students and educators with quantitative feedback on learning a specific surgical procedure. Methods involved examine quantitative data of improvement in surgical skills. Herein, we qualitatively describe the method and show how program directors (PDs) may implement this technique in their residencies. Results CEVL allows an operation to be broken down into teachable components. The process relies on feedback and remediation to improve performance, with a focus on learning that is applicable to the next case being performed. CEVL has been shown to be effective for teaching pediatric orchiopexy and is being adapted to additional adult and pediatric procedures and to office examination skills. The CEVL method is available to other residency training programs. PMID:21975716

Single-tooth anesthesia: pressure-sensing technology provides innovative advancement in the field of dental local anesthesia.

PubMed

Hochman, Mark N

2007-04-01

This article will review standard techniques for intraligamentary injection and describe the technology and technique behind a new single-tooth anesthesia system. This system and technique represents a technological advancement and a greater understanding of intraligamentary anesthesia.

Innovative Techniques to Model, Analyze and Monitor Space Effects on Air Force Space-Based Systems

DTIC Science & Technology

2010-03-20

of Comets in the Heliosphere as Observed by SMEI 4 2.8. Zodiacal Light Observations and Modeling 5 2.9. Space Weather Forecasting Lab (SWFL...This research resulted in two publications and a presentation at the 2007 American Geophysical Union Fall Meeting. 2.8. Zodiacal Light Observations...and Modeling One of the backgrounds removed from SMEI imagery is the scattered zodiacal light from solar system dust. The zodiacal light has

[Preface for genome editing special issue].

PubMed

Gu, Feng; Gao, Caixia

2017-10-25

Genome editing technology, as an innovative biotechnology, has been widely used for editing the genome from model organisms, animals, plants and microbes. CRISPR/Cas9-based genome editing technology shows its great value and potential in the dissection of functional genomics, improved breeding and genetic disease treatment. In the present special issue, the principle and application of genome editing techniques has been summarized. The advantages and disadvantages of the current genome editing technology and future prospects would also be highlighted.

Proceedings of the Digital/Electronic Terrain Board Symposium Held in Wichita, Kansas on 5-6 October 1989

DTIC Science & Technology

1990-02-01

Representative is Mr. H. C. Race, AMC Smart Weapons Management Office, ATTN: AMSMI-SW, Redstone Arsenal, Alabama 35898- 5222. Reproduction. Permission to...reproduce any material contained in this document must be requested and approved in writing by the AMC Smart Weapons Management Office, AMSMI-SW, Redstone...elevation points, necessitating a large geometric data base that requires heavy computation loads for rendering. The second innovative technique is the

Peak horizontal acceleration and velocity from strong-motion records including records from the 1979 imperial valley, California, earthquake

USGS Publications Warehouse

Joyner, William B.; Boore, David M.

1981-01-01

We have taken advantage of the recent increase in strong-motion data at close distances to derive new attenuation relations for peak horizontal acceleration and velocity. This new analysis uses a magnitude-independent shape, based on geometrical spreading and anelastic attenuation, for the attenuation curve. An innovation in technique is introduced that decouples the determination of the distance dependence of the data from the magnitude dependence.

Compressive Sampling Based Interior Reconstruction for Dynamic Carbon Nanotube Micro-CT

PubMed Central

Yu, Hengyong; Cao, Guohua; Burk, Laurel; Lee, Yueh; Lu, Jianping; Santago, Pete; Zhou, Otto; Wang, Ge

2010-01-01

In the computed tomography (CT) field, one recent invention is the so-called carbon nanotube (CNT) based field emission x-ray technology. On the other hand, compressive sampling (CS) based interior tomography is a new innovation. Combining the strengths of these two novel subjects, we apply the interior tomography technique to local mouse cardiac imaging using respiration and cardiac gating with a CNT based micro-CT scanner. The major features of our method are: (1) it does not need exact prior knowledge inside an ROI; and (2) two orthogonal scout projections are employed to regularize the reconstruction. Both numerical simulations and in vivo mouse studies are performed to demonstrate the feasibility of our methodology. PMID:19923686

Wavelet Filter Banks for Super-Resolution SAR Imaging

NASA Technical Reports Server (NTRS)

Sheybani, Ehsan O.; Deshpande, Manohar; Memarsadeghi, Nargess

2011-01-01

This paper discusses Innovative wavelet-based filter banks designed to enhance the analysis of super resolution Synthetic Aperture Radar (SAR) images using parametric spectral methods and signal classification algorithms, SAR finds applications In many of NASA's earth science fields such as deformation, ecosystem structure, and dynamics of Ice, snow and cold land processes, and surface water and ocean topography. Traditionally, standard methods such as Fast-Fourier Transform (FFT) and Inverse Fast-Fourier Transform (IFFT) have been used to extract Images from SAR radar data, Due to non-parametric features of these methods and their resolution limitations and observation time dependence, use of spectral estimation and signal pre- and post-processing techniques based on wavelets to process SAR radar data has been proposed. Multi-resolution wavelet transforms and advanced spectral estimation techniques have proven to offer efficient solutions to this problem.

MS-Based Analytical Techniques: Advances in Spray-Based Methods and EI-LC-MS Applications

PubMed Central

Medina, Isabel; Cappiello, Achille; Careri, Maria

2018-01-01

Mass spectrometry is the most powerful technique for the detection and identification of organic compounds. It can provide molecular weight information and a wealth of structural details that give a unique fingerprint for each analyte. Due to these characteristics, mass spectrometry-based analytical methods are showing an increasing interest in the scientific community, especially in food safety, environmental, and forensic investigation areas where the simultaneous detection of targeted and nontargeted compounds represents a key factor. In addition, safety risks can be identified at the early stage through online and real-time analytical methodologies. In this context, several efforts have been made to achieve analytical instrumentation able to perform real-time analysis in the native environment of samples and to generate highly informative spectra. This review article provides a survey of some instrumental innovations and their applications with particular attention to spray-based MS methods and food analysis issues. The survey will attempt to cover the state of the art from 2012 up to 2017. PMID:29850370

Digital multicolor printing: state of the art and future challenges

NASA Astrophysics Data System (ADS)

Kipphan, Helmut

1995-04-01

During the last 5 years, digital techniques have become extremely important in the graphic arts industry. All sections in the production flow for producing multicolor printed products - prepress, printing and postpress - are influenced by digitalization, in an evolutionary and revolutionary way. New equipment and network techniques bring all the sections closer together. The focus is put on high-quality multicolor printing, together with high productivity. Conventional offset printing technology is compared with the leading nonimpact printing technologies. Computer to press is contrasted with computer to print techniques. The newest available digital multicolor presses are described - the direct imaging offset printing press from HEIDELBERG with new laser imaging technique as well as the INDIGO and XEIKON presses based on electrophotography. Regarding technical specifications, economic calculations and print quality, it is worked out that each technique has its own market segments. An outlook is given for future computer to press techniques and the potential of nonimpact printing technologies for advanced high-speed multicolor computer to print equipment. Synergy effects from the NIP-technologies to the conventional printing technologies and vice versa are possible for building up innovative new products, for example hybrid printing systems. It is also shown that there is potential for improving the print quality, based on special screening algorithms, and a higher number of grey levels per pixel by using NIP-technologies. As an intermediate step in digitalization of the production flow, but also as an economical solution computer to plate equipment is described. By producing printed products totally in a digital way, digital color proofing as well as color management systems are needed. The newest high-tech equipment using NIP-technologies for producing proofs is explained. All in all it is shown that the state of the art in digital multicolor printing has reached a very high level in technology, productivity and quality, but that there is still space for improvements and innovations. Manufacturers of equipment and producers of printed products can take part in a successful evolution-changes, chances and challenges must be recognized and considered for future orientated activities and investments.

Consumer acceptance of technology-based food innovations: lessons for the future of nutrigenomics.

PubMed

Ronteltap, A; van Trijp, J C M; Renes, R J; Frewer, L J

2007-07-01

Determinants of consumer adoption of innovations have been studied from different angles and from the perspectives of various disciplines. In the food area, the literature is dominated by a focus on consumer concern. This paper reviews previous research into acceptance of technology-based innovation from both inside and outside the food domain, extracts key learnings from this literature and integrates them into a new conceptual framework for consumer acceptance of technology-based food innovations. The framework distinguishes 'distal' and 'proximal' determinants of acceptance. Distal factors (characteristics of the innovation, the consumer and the social system) influence consumers' intention to accept an innovation through proximal factors (perceived cost/benefit considerations, perceptions of risk and uncertainty, social norm and perceived behavioural control). The framework's application as a tool to anticipate consumer reaction to future innovations is illustrated for an actual technology-based innovation in food science, nutrigenomics (the interaction between nutrition and human genetics).

ABC deck panel testing.

DOT National Transportation Integrated Search

2013-09-01

Accelerated Bridge Construction techniques have resulted in innovative options that : save time and money during the construction of bridges. One such group of techniques : that has generated considerable interest is the usage of individual precast c...

Exploring the feasibility of Conjoint Analysis as a tool for prioritizing innovations for implementation

PubMed Central

2013-01-01

Background In an era of scarce and competing priorities for implementation, choosing what to implement is a key decision point for many behavioural change projects. The values and attitudes of the professionals and managers involved inevitably impact the priority attached to decision options. Reliably capturing such values is challenging. Methods This paper presents an approach for capturing and incorporating professional values into the prioritization of healthcare innovations being considered for adoption. Conjoint Analysis (CA) was used in a single UK Primary Care Trust to measure the priorities of healthcare professionals working with women with postnatal depression. Rating-based CA data was gathered using a questionnaire and then mapped onto 12 interventions being considered as a means of improving the management of postnatal depression. Results The ‘impact on patient care’ and the ‘quality of supporting evidence’ associated with the potential innovations were the most influential in shaping priorities. Professionals were least influenced by whether an innovation was an existing national or local priority, or whether current practice in the Trust was meeting minimum standards. Ranking the 12 innovations by the preferences of potential adopters revealed ‘guided self help’ was the top priority for implementation and ‘screening questions for post natal depression’ the least. When other factors were considered (such as the presence of routine data or planned implementation activity elsewhere in the Trust), the project team chose to combine the eight related treatments and implement these as a single innovation referred to as ‘psychological therapies’. Conclusions Using Conjoint Analysis to prioritise potential innovation implementation options is a feasible means of capturing the utility of stakeholders and thus increasing the chances of an innovation being adopted. There are some practical barriers to overcome such as increasing response rates to conjoint surveys before routine and unevaluated use of this technique should be considered. PMID:23714429

BINP accelerator based epithermal neutron source.

PubMed

Aleynik, V; Burdakov, A; Davydenko, V; Ivanov, A; Kanygin, V; Kuznetsov, A; Makarov, A; Sorokin, I; Taskaev, S

2011-12-01

Innovative facility for neutron capture therapy has been built at BINP. This facility is based on compact vacuum insulation tandem accelerator designed to produce proton current up to 10 mA. Epithermal neutrons are proposed to be generated by 1.915-2.5 MeV protons bombarding a lithium target using (7)Li(p,n)(7)Be threshold reaction. In the article, diagnostic techniques for proton beam and neutrons developed are described, results of experiments on proton beam transport and neutron generation are shown, discussed, and plans are presented. Copyright © 2011 Elsevier Ltd. All rights reserved.

Spatial Paradigm for Information Retrieval and Exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

The SPIRE system consists of software for visual analysis of primarily text based information sources. This technology enables the content analysis of text documents without reading all the documents. It employs several algorithms for text and word proximity analysis. It identifies the key themes within the text documents. From this analysis, it projects the results onto a visual spatial proximity display (Galaxies or Themescape) where items (documents and/or themes) visually close to each other are known to have content which is close to each other. Innovative interaction techniques then allow for dynamic visual analysis of large text based information spaces.

SPIRE1.03. Spatial Paradigm for Information Retrieval and Exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, K.J.; Bohn, S.; Crow, V.

The SPIRE system consists of software for visual analysis of primarily text based information sources. This technology enables the content analysis of text documents without reading all the documents. It employs several algorithms for text and word proximity analysis. It identifies the key themes within the text documents. From this analysis, it projects the results onto a visual spatial proximity display (Galaxies or Themescape) where items (documents and/or themes) visually close to each other are known to have content which is close to each other. Innovative interaction techniques then allow for dynamic visual analysis of large text based information spaces.

MIP sensors--the electrochemical approach.

PubMed

Malitesta, Cosimino; Mazzotta, Elisabetta; Picca, Rosaria A; Poma, Alessandro; Chianella, Iva; Piletsky, Sergey A

2012-02-01

This review highlights the importance of coupling molecular imprinting technology with methodology based on electrochemical techniques for the development of advanced sensing devices. In recent years, growing interest in molecularly imprinted polymers (MIPs) in the preparation of recognition elements has led researchers to design novel formats for improvement of MIP sensors. Among possible approaches proposed in the literature on this topic, we will focus on the electrosynthesis of MIPs and on less common hybrid technology (e.g. based on electrochemistry and classical MIPs, or nanotechnology). Starting from the early work reported in this field, an overview of the most innovative and successful examples will be reviewed.

NASA Innovation Builds Better Nanotubes

NASA Technical Reports Server (NTRS)

2008-01-01

Nanotailor Inc., based in Austin, Texas, licensed Goddard Space Flight Center's unique single-walled carbon nanotube (SWCNT) fabrication process with plans to make high-quality, low-cost SWCNTs available commercially. Carbon nanotubes are being used in a wide variety of applications, and NASA's improved production method will increase their applicability in medicine, microelectronics, advanced materials, and molecular containment. Nanotailor built and tested a prototype based on Goddard's process, and is using this technique to lower the cost and improve the integrity of nanotubes, offering a better product for use in biomaterials, advanced materials, space exploration, highway and building construction, and many other applications.

A New Real - Time Fault Detection Methodology for Systems Under Test. Phase 1

NASA Technical Reports Server (NTRS)

Johnson, Roger W.; Jayaram, Sanjay; Hull, Richard A.

1998-01-01

The purpose of this research is focussed on the identification/demonstration of critical technology innovations that will be applied to various applications viz. Detection of automated machine Health Monitoring (BM, real-time data analysis and control of Systems Under Test (SUT). This new innovation using a High Fidelity Dynamic Model-based Simulation (BFDMS) approach will be used to implement a real-time monitoring, Test and Evaluation (T&E) methodology including the transient behavior of the system under test. The unique element of this process control technique is the use of high fidelity, computer generated dynamic models to replicate the behavior of actual Systems Under Test (SUT). It will provide a dynamic simulation capability that becomes the reference truth model, from which comparisons are made with the actual raw/conditioned data from the test elements.

BREAST: a novel method to improve the diagnostic efficacy of mammography

NASA Astrophysics Data System (ADS)

Brennan, P. C.; Tapia, K.; Ryan, J.; Lee, W.

2013-03-01

High quality breast imaging and accurate image assessment are critical to the early diagnoses, treatment and management of women with breast cancer. Breast Screen Reader Assessment Strategy (BREAST) provides a platform, accessible by researchers and clinicians world-wide, which will contain image data bases, algorithms to assess reader performance and on-line systems for image evaluation. The platform will contribute to the diagnostic efficacy of breast imaging in Australia and beyond on two fronts: reducing errors in mammography, and transforming our assessment of novel technologies and techniques. Mammography is the primary diagnostic tool for detecting breast cancer with over 800,000 women X-rayed each year in Australia, however, it fails to detect 30% of breast cancers with a number of missed cancers being visible on the image [1-6]. BREAST will monitor the mistakes, identify reasons for mammographic errors, and facilitate innovative solutions to reduce error rates. The BREAST platform has the potential to enable expert assessment of breast imaging innovations, anywhere in the world where experts or innovations are located. Currently, innovations are often being assessed by limited numbers of individuals who happen to be geographically located close to the innovation, resulting in equivocal studies with low statistical power. BREAST will transform this current paradigm by enabling large numbers of experts to assess any new method or technology using our embedded evaluation methods. We are confident that this world-first system will play an important part in the future efficacy of breast imaging.

Present challenges in hadrontherapy techniques

NASA Astrophysics Data System (ADS)

Amaldi, U.; Braccini, S.

2011-07-01

Hadrontherapy is a high-precision technique in cancer radiation therapy, which allows obtaining a superior conformal treatment with respect to photons used in conventional radiation therapy. To reach this ambitious goal without reducing the patient throughput needed in a hospital-based environment, the physical and radiobiological properties of charged hadrons, protons and carbon ions in particular, have to be exploited at best, making use of the most modern technologies issued from research in nuclear and particle physics. In the present days, we are assisting to a continuous technological challenge, leading to the conception and to the development of innovative methods and instruments. In this paper, the most relevant challenges in dose delivery systems, gantries, imaging, quality assurance and particle accelerators are reviewed.

Grasping the health horizon: toward a virtual, interoperable platform of health innovations.

PubMed

Dawe, Marcus; Dugdale, Paul; Mcgann, Mathew

2015-01-01

The emergence of digital health, wearables, apps, telehealth and the proliferation of health services online are all indications that health is undergoing rapid innovation. Health innovation however has been traditionally slow, high cost and the commercialisation journey was not a guaranteed path to adoption outside the setting where it was developed whether in a hospital, university, clinic or lab. Most significant with this new explosion of health innovations is the sheer volume. The startup revolution, mobile health, personalised heath and globalisation of knowledge means that consumers are demanding innovations and are pulling health innovations through commercialisation with new modes of funding such as crowdsourcing and direct vendor purchases. Our Australian team initiated a project to use machine learning, data mining and classification techniques to bring together and analyse this expansion of heath innovations from all over the world. Following two years of data aggregation and quality analysis we present our findings which are applied to over 200,000 innovations from more than 25,000 organisations. Our findings have identified the dynamics and basis for a marketplace for health innovations that could assist innovators, health practitioners, consumers, investors and other health participants to research, evaluate and promote these innovations.

Concurrent Probabilistic Simulation of High Temperature Composite Structural Response

NASA Technical Reports Server (NTRS)

Abdi, Frank

1996-01-01

A computational structural/material analysis and design tool which would meet industry's future demand for expedience and reduced cost is presented. This unique software 'GENOA' is dedicated to parallel and high speed analysis to perform probabilistic evaluation of high temperature composite response of aerospace systems. The development is based on detailed integration and modification of diverse fields of specialized analysis techniques and mathematical models to combine their latest innovative capabilities into a commercially viable software package. The technique is specifically designed to exploit the availability of processors to perform computationally intense probabilistic analysis assessing uncertainties in structural reliability analysis and composite micromechanics. The primary objectives which were achieved in performing the development were: (1) Utilization of the power of parallel processing and static/dynamic load balancing optimization to make the complex simulation of structure, material and processing of high temperature composite affordable; (2) Computational integration and synchronization of probabilistic mathematics, structural/material mechanics and parallel computing; (3) Implementation of an innovative multi-level domain decomposition technique to identify the inherent parallelism, and increasing convergence rates through high- and low-level processor assignment; (4) Creating the framework for Portable Paralleled architecture for the machine independent Multi Instruction Multi Data, (MIMD), Single Instruction Multi Data (SIMD), hybrid and distributed workstation type of computers; and (5) Market evaluation. The results of Phase-2 effort provides a good basis for continuation and warrants Phase-3 government, and industry partnership.

Innovative Techniques for Estimating Illegal Activities in a Human-Wildlife-Management Conflict

PubMed Central

Cross, Paul; St. John, Freya A. V.; Khan, Saira; Petroczi, Andrea

2013-01-01

Effective management of biological resources is contingent upon stakeholder compliance with rules. With respect to disease management, partial compliance can undermine attempts to control diseases within human and wildlife populations. Estimating non-compliance is notoriously problematic as rule-breakers may be disinclined to admit to transgressions. However, reliable estimates of rule-breaking are critical to policy design. The European badger (Meles meles) is considered an important vector in the transmission and maintenance of bovine tuberculosis (bTB) in cattle herds. Land managers in high bTB prevalence areas of the UK can cull badgers under license. However, badgers are also known to be killed illegally. The extent of illegal badger killing is currently unknown. Herein we report on the application of three innovative techniques (Randomized Response Technique (RRT); projective questioning (PQ); brief implicit association test (BIAT)) for investigating illegal badger killing by livestock farmers across Wales. RRT estimated that 10.4% of farmers killed badgers in the 12 months preceding the study. Projective questioning responses and implicit associations relate to farmers' badger killing behavior reported via RRT. Studies evaluating the efficacy of mammal vector culling and vaccination programs should incorporate estimates of non-compliance. Mitigating the conflict concerning badgers as a vector of bTB requires cross-disciplinary scientific research, departure from deep-rooted positions, and the political will to implement evidence-based management. PMID:23341973

Innovative techniques for estimating illegal activities in a human-wildlife-management conflict.

PubMed

Cross, Paul; St John, Freya A V; Khan, Saira; Petroczi, Andrea

2013-01-01

Effective management of biological resources is contingent upon stakeholder compliance with rules. With respect to disease management, partial compliance can undermine attempts to control diseases within human and wildlife populations. Estimating non-compliance is notoriously problematic as rule-breakers may be disinclined to admit to transgressions. However, reliable estimates of rule-breaking are critical to policy design. The European badger (Meles meles) is considered an important vector in the transmission and maintenance of bovine tuberculosis (bTB) in cattle herds. Land managers in high bTB prevalence areas of the UK can cull badgers under license. However, badgers are also known to be killed illegally. The extent of illegal badger killing is currently unknown. Herein we report on the application of three innovative techniques (Randomized Response Technique (RRT); projective questioning (PQ); brief implicit association test (BIAT)) for investigating illegal badger killing by livestock farmers across Wales. RRT estimated that 10.4% of farmers killed badgers in the 12 months preceding the study. Projective questioning responses and implicit associations relate to farmers' badger killing behavior reported via RRT. Studies evaluating the efficacy of mammal vector culling and vaccination programs should incorporate estimates of non-compliance. Mitigating the conflict concerning badgers as a vector of bTB requires cross-disciplinary scientific research, departure from deep-rooted positions, and the political will to implement evidence-based management.

Ecological generalism and behavioural innovation in birds: technical intelligence or the simple incorporation of new foods?

PubMed

Ducatez, Simon; Clavel, Joanne; Lefebvre, Louis

2015-01-01

Generalist species are more successful than specialists in anthropogenically modified environments or in environments in which they have been introduced, but the nature of the link between generalism and establishment success is unclear. A higher feeding innovation rate has previously been reported in habitat generalist birds from North America. By allowing them to exploit new resources, this higher feeding innovation rate might explain the generalists' advantage. This result might be due to generalists being more likely to find new resources because they are exposed to more diverse environmental conditions. Alternatively, they might differ from specialists in other traits, in particular cognitive skills that might allow them to innovate more complex food searching and handling techniques. To test these hypotheses, we separated avian feeding innovations into a 'technical' (novel searching and handling behaviour) and a 'food type' (incorporation of a new food in a species' diet) category. Technical innovations, but not food type innovations, have previously been shown to correlate with avian brain size, suggesting they reflect cognitive ability. We used a world-wide data base of 2339 feeding innovations recorded in the literature, covering a total of 765 avian species and assessed the correlations between brain size and feeding innovation rates on one side and habitat and diet generalism on the other. Habitat generalism was positively related with food type innovation rate, but not technical innovation rate or brain size. This suggests that habitat generalist species are more likely to incorporate new food types in their diet because of higher chances to find new food resources in their environment, or of a higher opportunism, but not enhanced cognitive skills. In contrast, diet generalist species had higher food type and technical innovation rates, as well as larger brains, suggesting that cognitive skills might help species expand their diet breadth or that an increase in diet breadth might favour the evolution of enhanced cognitive abilities. Our results provide new insights into the nature of the generalists' advantage in the face of environmental changes, and suggest that dietary and habitat generalism are different, but convergent, routes to feeding flexibility and adaptation to changed environments. © 2014 The Authors. Journal of Animal Ecology © 2014 British Ecological Society.

Getting Clearer About Surgical Innovation: A New Definition and a New Tool to Support Responsible Practice.

PubMed

Hutchison, Katrina; Rogers, Wendy; Eyers, Anthony; Lotz, Mianna

2015-12-01

This article presents an original definition of surgical innovation and a practical tool for identifying planned innovations. These will support the responsible introduction of surgical innovations. Frameworks developed for the safer introduction of surgical innovations rely upon identifying cases of innovation; oversight cannot occur unless innovations are identified. However, there is no consensus among surgeons about which interventions they consider innovative; existing definitions are vague and impractical. Using conceptual analysis, this article synthesizes findings from relevant literature, and from qualitative research with surgeons, to develop an original definition of surgical innovation and a tool for prospectively identifying planned surgical innovations. The tool has been developed in light of feedback from health care professionals, surgeons, and policy makers. This definition of innovation distinguishes between variations, introduction of established interventions, and innovations in surgical techniques or use of devices. It can be applied easily and consistently, is sensitive to the key features of innovation (newness and degree of change), is prospective, and focuses on features relevant to safety and evaluation. The accompanying tool is deliberately broad so that appropriate supports may, if necessary, be provided each time that a surgeon does something "new." The definition presented in this article overcomes a number of practical challenges. The definition and tool will be of value in supporting responsible surgical innovation, in particular, through the prospective identification of planned innovations.

Technological innovation capability in Malaysian-owned resource-based manufacturing companies: Early findings

NASA Astrophysics Data System (ADS)

Razali, Nur Fhathyhah; Mohd Suradi, Nur Riza; Ahmad Shahabuddin, Faridatul Azna; Ismail, Wan Rosmanira; Abidin, Norkisme Zainal; Ahmad, Nor Amalina; Mustafa, Zainol

2013-04-01

This study aims to identify the determinants of technological innovation capability of Malaysian-owned companies in the resources-based manufacturing, to identify the relationship between technological innovation capability (TIC) and technological innovation performance (TIP) for the resource-based manufacturing. Furthermore, this study also aims to identify innovation capability factors that need more emphasis and improvements from the respective authority. The scope of the study covers four industries which are petrochemical industries, pharmaceutical industries, palm oil-based industries and food processing industries which are located in the state of Selangor. Descriptive analysis, correlation analysis and performance capability analysis were used in this study. It was found that, technological innovation capabilities (TIC) for companies in the resource-based manufacturing are moderate. Factors such as policies capability, human resources capability and facilities capability have a positive relationship with the performance of technological innovation (TIP). These findings will help the government in making decisions and better implementation of policies to strengthen the competitiveness of the company, particularly in resource-based manufacturing.

Aerospace management techniques: Commercial and governmental applications

NASA Technical Reports Server (NTRS)

Milliken, J. G.; Morrison, E. J.

1971-01-01

A guidebook for managers and administrators is presented as a source of useful information on new management methods in business, industry, and government. The major topics discussed include: actual and potential applications of aerospace management techniques to commercial and governmental organizations; aerospace management techniques and their use within the aerospace sector; and the aerospace sector's application of innovative management techniques.

Research on collaborative innovation mechanism of green construction supply chain based on united agency

NASA Astrophysics Data System (ADS)

Zhang, Min; He, Weiyi

2018-06-01

Under the guidance of principal-agent theory and modular theory, the collaborative innovation of green technology-based companies, design contractors and project builders based on united agency will provide direction for the development of green construction supply chain in the future. After analyzing the existing independent agencies, this paper proposes the industry-university-research bilateral collaborative innovation network architecture and modularization with the innovative function of engineering design in the context of non-standard transformation interfaces, analyzes the innovation responsibility center, and gives some countermeasures and suggestions to promote the performance of bilateral cooperative innovation network.

Practical Application of Model-based Programming and State-based Architecture to Space Missions

NASA Technical Reports Server (NTRS)

Horvath, Gregory A.; Ingham, Michel D.; Chung, Seung; Martin, Oliver; Williams, Brian

2006-01-01

Innovative systems and software engineering solutions are required to meet the increasingly challenging demands of deep-space robotic missions. While recent advances in the development of an integrated systems and software engineering approach have begun to address some of these issues, they are still at the core highly manual and, therefore, error-prone. This paper describes a task aimed at infusing MIT's model-based executive, Titan, into JPL's Mission Data System (MDS), a unified state-based architecture, systems engineering process, and supporting software framework. Results of the task are presented, including a discussion of the benefits and challenges associated with integrating mature model-based programming techniques and technologies into a rigorously-defined domain specific architecture.

Strategic proposal for a national trauma system in France.

PubMed

Gauss, Tobias; Balandraud, Paul; Frandon, Julien; Abba, Julio; Ageron, Francois Xavier; Albaladejo, Pierre; Arvieux, Catherine; Barbois, Sandrine; Bijok, Benjamin; Bobbia, Xavier; Charbit, Jonathan; Cook, Fabrice; David, Jean-Stephane; Maurice, Guillaume De Saint; Duranteau, Jacques; Garrigue, Delphine; Gay, Emmanuel; Geeraerts, Thomas; Ghelfi, Julien; Hamada, Sophie; Harrois, Anatole; Kobeiter, Hicham; Leone, Marc; Levrat, Albrice; Mirek, Sebastien; Nadji, Abdel; Paugam-Burtz, Catherine; Payen, Jean Francois; Perbet, Sebastien; Pirracchio, Romain; Plenier, Isabelle; Pottecher, Julien; Rigal, Sylvain; Riou, Bruno; Savary, Dominique; Secheresse, Thierry; Tazarourte, Karim; Thony, Frederic; Tonetti, Jerome; Tresallet, Christophe; Wey, Pierre-Francois; Picard, Julien; Bouzat, Pierre

2018-05-29

In this road map for trauma in France, we focus on the main challenges for system implementation, surgical and radiology training, and upon innovative training techniques. Regarding system organisation: procedures for triage, designation and certification of trauma centres are mandatory to implement trauma networks on a national scale. Data collection with registries must be created, with a core dataset defined and applied through all registries. Regarding surgical and radiology training, diagnostic-imaging processes should be standardised and the role of the interventional radiologist within the trauma team and the trauma network should be clearly defined. Education in surgery for trauma is crucial and recent changes in medical training in France will promote trauma surgery as a specific sub-specialty. Innovative training techniques should be implemented and be based on common objectives, scenarios and evaluation, so as to improve individual and team performances. The group formulated 14 proposals that should help to structure and improve major trauma management in France over the next 10 years. Copyright © 2018 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

INNOVATIVE CONCEPTS FOR DETECTING AND LOCATING LEAKS IN WASTE IMPOUNDMENT LINER SYSTEMS: ACOUSTIC EMISSION MONITORING AND TIME DOMAIN REFLECTOMETRY

EPA Science Inventory

This project is part of a program to investigate the use of innovative techniques for detecting and locating leaks in waste impoundment liners. Laboratory and small scale field studies were undertaken to evaluate the potential of Acoustic Emission Monitoring (AEM) and Time Domain...

Distributive Marketing Education: Innovative Instructional Techniques in Distributive Marketing Education.

ERIC Educational Resources Information Center

Office of Education (DHEW), Washington, DC.

The conference featured more than 40 presentations representing existing and planned innovative programs in all levels of distributive marketing education in six States. In addition to the presentations (not reproduced in their entirety in the report), there were sessions and workshops for secondary, post secondary, and adult levels and for city…

Which Advisory System to Support Innovation in Conservation Agriculture? The Case of Madagascar's Lake Alaotra

ERIC Educational Resources Information Center

Faure, Guy; Penot, Eric; Rakotondravelo, Jean Chrysostome; Ramahatoraka, Haja Andrisoa; Dugue, Patrick; Toillier, Aurelie

2013-01-01

Purpose: To promote sustainable agriculture, various development projects are encouraging farmers around Madagascar's Lake Alaotra to adopt conservation agriculture techniques. This article's objective is to analyze the capacity of a project-funded advisory system to accompany such an innovation and to design and implement an advisory method aimed…

Focused Group Interviews as an Innovative Quanti-Qualitative Methodology (QQM): Integrating Quantitative Elements into a Qualitative Methodology

ERIC Educational Resources Information Center

Grim, Brian J.; Harmon, Alison H.; Gromis, Judy C.

2006-01-01

There is a sharp divide between quantitative and qualitative methodologies in the social sciences. We investigate an innovative way to bridge this gap that incorporates quantitative techniques into a qualitative method, the "quanti-qualitative method" (QQM). Specifically, our research utilized small survey questionnaires and experiment-like…

NASA Chief Technologist on Panel at Massachusetts Institute of Technology

NASA Image and Video Library

2018-02-15

During MIT's "Better MIT Innovation Week 2018," a group of experts discussed innovation as a critical component to and professional accomplishment. From left: Rebecca Chui, founder, RootsStudio; Reinaldo Normand, entrepreneur in residence, MIT; Douglas Terrier, NASA chief technologist; Linda Foster, chief technologist, Lockheed Martin. (Photo: Damian Barabonkov/MIT Technique)

NASA Chief Technologist Speaks at Massachusetts Institute of Technology

NASA Image and Video Library

2018-02-15

NASA Chief Technologist Douglas Terrier joined students, faculty and experts in Boston as part of MIT's "Better MIT Innovation Week 2018," a week-long program promoting leadership, entrepreneurship and action for a better future. During the February event, Terrier spoke about a culture of innovation at America's Space Program. (Photo: Damian Barabonkov/MIT Technique)

Innovative Teaching Ideas. A Sharing of Teaching Tips, Ideas and Methods.

ERIC Educational Resources Information Center

Tenney, Richard W., Ed.; And Others

Compiled from materials collected from 150 teachers of agriculture across New York State who participated in a series of 11 regional agriculture inservice workshops, this resource guide contains innovative techniques for classroom operation as well as suggestions for using available resources. The ideas have been organized into the following eight…

Towards microscale electrohydrodynamic three-dimensional printing

NASA Astrophysics Data System (ADS)

He, Jiankang; Xu, Fangyuan; Cao, Yi; Liu, Yaxiong; Li, Dichen

2016-02-01

It is challenging for the existing three-dimensional (3D) printing techniques to fabricate high-resolution 3D microstructures with low costs and high efficiency. In this work we present a solvent-based electrohydrodynamic 3D printing technique that allows fabrication of microscale structures like single walls, crossed walls, lattice and concentric circles. Process parameters were optimized to deposit tiny 3D patterns with a wall width smaller than 10 μm and a high aspect ratio of about 60. Tight bonding among neighbour layers could be achieved with a smooth lateral surface. In comparison with the existing microscale 3D printing techniques, the presented method is low-cost, highly efficient and applicable to multiple polymers. It is envisioned that this simple microscale 3D printing strategy might provide an alternative and innovative way for application in MEMS, biosensor and flexible electronics.

Pursuing Innovation: Benchmarking Milwaukee's Transition to a Knowledge-Based Economy. Metro Milwaukee Innovation Index 2010

ERIC Educational Resources Information Center

Million, Laura; Dickman, Anneliese; Henken, Rob

2010-01-01

While the Milwaukee region's economic base is rooted in its manufacturing history, many believe that the region's future prosperity will be tied to its ability to successfully transition its economy into one that is based on knowledge and innovation. Indeed, fostering innovation has become the call to action for business and political leaders…

Current state of the art, multimodality research and future visions for the treatment of patients with prostate cancer: consensus results from "Challenges and Chances in Prostate Cancer Research Meeting 2013".

PubMed

Combs, Stephanie E; Debus, Jürgen; Feick, Günter; Hadaschik, Boris; Hohenfellner, Markus; Schüle, Roland; Zacharias, Jens-Peter; Schwardt, Malte

2014-11-04

A brainstorming and consensus meeting organized by the German Cancer Aid focused on modern treatment of prostate cancer and promising innovative techniques and research areas. Besides optimization of screening algorithms, molecular-based stratification and individually tailored treatment regimens will be the future of multimodal prostate cancer management. Effective interdisciplinary structures, including biobanking and data collection mechanisms are the basis for such developments.

Discovering complementary colors from the perspective of steam education

NASA Astrophysics Data System (ADS)

Karabey, Burak; Yigit Koyunkaya, Melike; Enginoglu, Turan; Yurumezoglu, Kemal

2018-05-01

This study explored the theory and applications of complementary colors using a technology-based activity designed from the perspective of STEAM education. Complementary colors and their areas of use were examined from the perspective of physics, mathematics and art, respectively. The study, which benefits from technology, makes the theory of complementary colors accessible to all through practical applications and provides a multidisciplinary, integrated and innovative technique of teaching the subject of colors, which could be used to teach complementary colors.

Incorporating social media into dermatologic education.

PubMed

Ko, Lauren N; Rana, Jasmine; Burgin, Susan

2017-10-15

In the current digital age, medical education has slowly evolved from the largely lecture-based teaching style of the past to incorporate more interactive pedagogical techniques, including use of social media. Already used readily by millennial trainees and clinicians, social media can also be used in innovative ways to teach trainees and facilitate continuing education among practicing clinicians. In this commentary, we discuss many learning benefits of social media and review potential pitfalls of employing social media in both trainee and physician dermatological education.

Space Transportation Avionics Technology Symposium. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1990-01-01

The focus of the symposium was to examine existing and planned avionics technology processes and products and to recommend necessary changes for strengthening priorities and program emphases. Innovative changes in avionics technology development and design processes, identified during the symposium, are needed to support the increasingly complex, multi-vehicle, integrated, autonomous space-based systems. Key technology advances make such a major initiative viable at this time: digital processing capabilities, integrated on-board test/checkout methods, easily reconfigurable laboratories, and software design and production techniques.

Space Transportation Avionics Technology Symposium. Volume 2: Conference Proceedings

NASA Technical Reports Server (NTRS)

1990-01-01

The focus of the symposium was to examine existing and planned avionics technology processes and products and to recommend necessary changes for strengthening priorities and program emphases. Innovative changes in avionics technology development and design processes are needed to support the increasingly complex, multi-vehicle, integrated, autonomous space-based systems. Key technology advances make such a major initiative viable at this time: digital processing capabilities, integrated on-board test/checkout methods, easily reconfigurable laboratories, and software design and production techniques.

Preventing spontaneous combustion after mine closing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewicki, G.

1987-11-01

The author explains how the Northern Coal Company and a Houston-based firefighting firm developed an innovative technique to reduce the risk of spontaneous combustion after mine closing in its Rienau number2 Mine. The ''Light Water TM'' ATC series of firefighting foam concentrates were designed for extinguishing flammable liquid fires. By slightly altering the chemicals, the concentrates could be used to seal the coal ribs, floor, and roof, reducing the risk of combustion. Subsequent monitoring of the mine has identified no signs of heating.

Cognitive learning: a machine learning approach for automatic process characterization from design

NASA Astrophysics Data System (ADS)

Foucher, J.; Baderot, J.; Martinez, S.; Dervilllé, A.; Bernard, G.

2018-03-01

Cutting edge innovation requires accurate and fast process-control to obtain fast learning rate and industry adoption. Current tools available for such task are mainly manual and user dependent. We present in this paper cognitive learning, which is a new machine learning based technique to facilitate and to speed up complex characterization by using the design as input, providing fast training and detection time. We will focus on the machine learning framework that allows object detection, defect traceability and automatic measurement tools.

Game-theoretic homological sensor resource management for SSA

NASA Astrophysics Data System (ADS)

Chin, Sang Peter

2009-05-01

We present a game-theoretic approach to Level 2/3/4 fusion for the purpose of Space Situational Awareness (SSA) along with prototypical SW implementation of this approach to demonstrate its effectiveness for possible future space operations. Our approach is based upon innovative techniques that we are developing to solve dynamic games and Nperson cooperative/non-cooperative games, as well as a new emerging homological sensing algorithms which we apply to control disparate network of space sensors in order to gain better SSA.

From 1D to 3D: Tunable Sub-10 nm Gaps in Large Area Devices.

PubMed

Zhou, Ziwei; Zhao, Zhiyuan; Yu, Ye; Ai, Bin; Möhwald, Helmuth; Chiechi, Ryan C; Yang, Joel K W; Zhang, Gang

2016-04-20

Tunable sub-10 nm 1D nanogaps are fabricated based on nanoskiving. The electric field in different sized nanogaps is investigated theoretically and experimentally, yielding nonmonotonic dependence and an optimized gap-width (5 nm). 2D nanogap arrays are fabricated to pack denser gaps combining surface patterning techniques. Innovatively, 3D multistory nanogaps are built via a stacking procedure, processing higher integration, and much improved electric field. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Recent Advances in Paper-Based Sensors

PubMed Central

Liana, Devi D.; Raguse, Burkhard; Gooding, J. Justin; Chow, Edith

2012-01-01

Paper-based sensors are a new alternative technology for fabricating simple, low-cost, portable and disposable analytical devices for many application areas including clinical diagnosis, food quality control and environmental monitoring. The unique properties of paper which allow passive liquid transport and compatibility with chemicals/biochemicals are the main advantages of using paper as a sensing platform. Depending on the main goal to be achieved in paper-based sensors, the fabrication methods and the analysis techniques can be tuned to fulfill the needs of the end-user. Current paper-based sensors are focused on microfluidic delivery of solution to the detection site whereas more advanced designs involve complex 3-D geometries based on the same microfluidic principles. Although paper-based sensors are very promising, they still suffer from certain limitations such as accuracy and sensitivity. However, it is anticipated that in the future, with advances in fabrication and analytical techniques, that there will be more new and innovative developments in paper-based sensors. These sensors could better meet the current objectives of a viable low-cost and portable device in addition to offering high sensitivity and selectivity, and multiple analyte discrimination. This paper is a review of recent advances in paper-based sensors and covers the following topics: existing fabrication techniques, analytical methods and application areas. Finally, the present challenges and future outlooks are discussed. PMID:23112667

[Technological innovations in radiation oncology require specific quality controls].

PubMed

Lenaerts, E; Mathot, M

2014-01-01

During the last decade, the field of radiotherapy has benefited from major technological innovations and continuously improving treatment efficacy, comfort and safety of patients. This mainly concerns the imaging techniques that allow 4D CT scan recording the respiratory phases, on-board imaging on linear accelerators that ensure perfect positioning of the patient for treatment and irradiation techniques that reduce very significantly the duration of treatment sessions without compromising quality of the treatment plan, including IMRT (Intensity Modulated Radiation Therapy) and VMAT (Volumetric Modulated Arc therapy). In this context of rapid technological change, it is the responsibility of medical physicists to regularly and precisely monitor the perfect functioning of new techniques to ensure patient safety. This requires the use of specific quality control equipment best suited to these new techniques. We will briefly describe the measurement system Delta4 used to control individualized treatment plan for each patient treated with VMAT technology.

Rise of the micromachines: microfluidics and the future of cytometry.

PubMed

Wlodkowic, Donald; Darzynkiewicz, Zbigniew

2011-01-01

The past decade has brought many innovations to the field of flow and image-based cytometry. These advancements can be seen in the current miniaturization trends and simplification of analytical components found in the conventional flow cytometers. On the other hand, the maturation of multispectral imaging cytometry in flow imaging and the slide-based laser scanning cytometers offers great hopes for improved data quality and throughput while proving new vistas for the multiparameter, real-time analysis of cells and tissues. Importantly, however, cytometry remains a viable and very dynamic field of modern engineering. Technological milestones and innovations made over the last couple of years are bringing the next generation of cytometers out of centralized core facilities while making it much more affordable and user friendly. In this context, the development of microfluidic, lab-on-a-chip (LOC) technologies is one of the most innovative and cost-effective approaches toward the advancement of cytometry. LOC devices promise new functionalities that can overcome current limitations while at the same time promise greatly reduced costs, increased sensitivity, and ultra high throughputs. We can expect that the current pace in the development of novel microfabricated cytometric systems will open up groundbreaking vistas for the field of cytometry, lead to the renaissance of cytometric techniques and most importantly greatly support the wider availability of these enabling bioanalytical technologies. Copyright © 2011 Elsevier Inc. All rights reserved.

Rise of the Micromachines: Microfluidics and the Future of Cytometry

PubMed Central

Wlodkowic, Donald; Darzynkiewicz, Zbigniew

2011-01-01

The past decade has brought many innovations to the field of flow and image-based cytometry. These advancements can be seen in the current miniaturization trends and simplification of analytical components found in the conventional flow cytometers. On the other hand, the maturation of multispectral imaging cytometry in flow imaging and the slide-based laser scanning cytometers offers great hopes for improved data quality and throughput while proving new vistas for the multiparameter, real-time analysis of cells and tissues. Importantly, however, cytometry remains a viable and very dynamic field of modern engineering. Technological milestones and innovations made over the last couple of years are bringing the next generation of cytometers out of centralized core facilities while making it much more affordable and user friendly. In this context, the development of microfluidic, lab-on-a-chip (LOC) technologies is one of the most innovative and cost-effective approaches toward the advancement of cytometry. LOC devices promise new functionalities that can overcome current limitations while at the same time promise greatly reduced costs, increased sensitivity, and ultra high throughputs. We can expect that the current pace in the development of novel microfabricated cytometric systems will open up groundbreaking vistas for the field of cytometry, lead to the renaissance of cytometric techniques and most importantly greatly support the wider availability of these enabling bioanalytical technologies. PMID:21704837

BMP analysis system for watershed-based stormwater management.

PubMed

Zhen, Jenny; Shoemaker, Leslie; Riverson, John; Alvi, Khalid; Cheng, Mow-Soung

2006-01-01

Best Management Practices (BMPs) are measures for mitigating nonpoint source (NPS) pollution caused mainly by stormwater runoff. Established urban and newly developing areas must develop cost effective means for restoring or minimizing impacts, and planning future growth. Prince George's County in Maryland, USA, a fast-growing region in the Washington, DC metropolitan area, has developed a number of tools to support analysis and decision making for stormwater management planning and design at the watershed level. These tools support watershed analysis, innovative BMPs, and optimization. Application of these tools can help achieve environmental goals and lead to significant cost savings. This project includes software development that utilizes GIS information and technology, integrates BMP processes simulation models, and applies system optimization techniques for BMP planning and selection. The system employs the ESRI ArcGIS as the platform, and provides GIS-based visualization and support for developing networks including sequences of land uses, BMPs, and stream reaches. The system also provides interfaces for BMP placement, BMP attribute data input, and decision optimization management. The system includes a stand-alone BMP simulation and evaluation module, which complements both research and regulatory nonpoint source control assessment efforts, and allows flexibility in the examining various BMP design alternatives. Process based simulation of BMPs provides a technique that is sensitive to local climate and rainfall patterns. The system incorporates a meta-heuristic optimization technique to find the most cost-effective BMP placement and implementation plan given a control target, or a fixed cost. A case study is presented to demonstrate the application of the Prince George's County system. The case study involves a highly urbanized area in the Anacostia River (a tributary to Potomac River) watershed southeast of Washington, DC. An innovative system of management practices is proposed to minimize runoff, improve water quality, and provide water reuse opportunities. Proposed management techniques include bioretention, green roof, and rooftop runoff collection (rain barrel) systems. The modeling system was used to identify the most cost-effective combinations of management practices to help minimize frequency and size of runoff events and resulting combined sewer overflows to the Anacostia River.

Pathways and Challenges to Innovation in Aerospace

NASA Technical Reports Server (NTRS)

Terrile, Richard J.

2010-01-01

This paper explores impediments to innovation in aerospace and suggests how successful pathways from other industries can be adopted to facilitate greater innovation. Because of its nature, space exploration would seem to be a ripe field of technical innovation. However, engineering can also be a frustratingly conservative endeavor when the realities of cost and risk are included. Impediments like the "find the fault" engineering culture, the treatment of technical risk as almost always evaluated in terms of negative impact, the difficult to account for expansive Moore's Law growth when making predictions, and the stove-piped structural organization of most large aerospace companies and federally funded research laboratories tend to inhibit cross-cutting technical innovation. One successful example of a multi-use cross cutting application that can scale with Moore's Law is the Evolutionary Computational Methods (ECM) technique developed at the Jet Propulsion Lab for automated spectral retrieval. Future innovations like computational engineering and automated design optimization can potentially redefine space exploration, but will require learning lessons from successful innovators.

Development of a national system for prevention and mitigation of earthquake damages to people and properties, and the reduction of costs related to earthquakes for the Italian Government

NASA Astrophysics Data System (ADS)

Console, R.; Greco, M.; Colangelo, A.; Cioè, A.; Trivigno, L.; Chiappini, M.; Ponzo, F.

2015-12-01

Recognizing that the Italian territory is prone to disasters in connection with seismic and hydro-geological risk, it has become necessary to define novel regulations and viable solutions aimed at conveying the economical resources of the Italian Government, too often utilized for the management of post-event situations, towards prevention activities. The work synthetically presents the project developed by the CGIAM together with the INGV, and open to collaboration with other Italian and International partners. This project is aimed at the development of a National System for prevention and mitigation of the earthquakes damages, through the definition of a model that achieves the mitigation of the building collapsing risk and the consequent reduction of casualties. Such a model is based on two main issues a) a correct evaluation of risk, defined as a reliable assessment of the hazard expected at a given site and of the vulnerability of civil and industrial buildings, b) setting up of novel strategies for the safety of buildings. The hazard assessment is pursued through the application of innovative multidisciplinary geophysical methodologies and the application of a physically based earthquake simulator. The structural vulnerability of buildings is estimated by means of simplified techniques based on few representative parameters (such as different structural typologies, dynamic soil-structure interaction, etc.) and, for detailed studies, standard protocols for model updating techniques. We analyze, through numerical and experimental approaches, new solutions for the use of innovative materials, and new techniques for the reduction of seismic vulnerability of structural, non-structural and accessorial elements, including low cost type. The project activities are initially implemented on a study area in Southern Italy (Calabria) selected because of its tectonic complexity. The results are expected to be applicable for other hazardous seismic areas of Italy.

Metallic multilayers at the nanoscale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jankowski, A.F.

1994-11-01

The development of multilayer structures has been driven by a wide range of commercial applications requiring enhanced material behaviors. Innovations in physical vapor deposition technologies, in particular magnetron sputtering, have enabled the synthesis of metallic-based structures with nanoscaled layer dimensions as small as one-to-two monolayers. Parameters used in the deposition process are paramount to the Formation of these small layer dimensions and the stability of the structure. Therefore, optimization of the desired material properties must be related to assessment of the actual microstructure. Characterization techniques as x-ray diffraction and high resolution microscopy are useful to reveal the interface and layermore » structure-whether ordered or disordered crystalline, amorphous, compositionally abrupt or graded, and/or lattice strained Techniques for the synthesis of metallic multilayers with subnanometric layers will be reviewed with applications based on enhancing material behaviors as reflectivity and magnetic anisotropy but with emphasis on experimental studies of mechanical properties.« less

Making sense of geoscientific concepts using active pedagogy techniques, a technology aided experience

NASA Astrophysics Data System (ADS)

Huguet, C.; Noè, L. F.; Pearse, J.; Gómez Pérez, M.; Valencia Lopez, D.; Jimenez Heredia, A.; Patiño Avedaño, M.

2016-12-01

This work is the result of a teaching innovation project funded by the Conecta-TE unit at Universidad de los Andes, Bogotá, Colombia and results from the collaborative work of a team of geoscience professors and pedagogic and technical support experts. The need for this innovation stems from the constraints of teaching an applied science subject to a large cohort of approximately 500 students per semester in five sections which makes it impossible to include laboratories or scientific outings. These factors are compounded by the fact this is an introductory core course for Geoscience but also a service course that can be taken by any student on campus whether they have a scientific background or not. Therefore our aim was double: making the basic concepts more understandable for a broad audience, while at the same time maintaining a sufficiently high level to challenge and form a sound basis for students from the Geosciences program. Additionally we wanted to incorporate more active and practical aspects to the subject in order to enhance student learning. This in itself was challenging with groups of over 90 students. Data on student understanding and satisfaction were collected both in classes where the innovation was implemented and others in which it was not. Generally our innovation was positively rated, however the students perceived that it involved more work than the traditional lecture-based classes, but they preferred the continual assessment to traditional homework. The methodology was improved and implemented fully for the second round of teaching by introducing the methodology and objectives more clearly. In the future we expect to reduce the number of activities per class (the ´less-is-more' approach) whilst at the same time increasing the amount of classes which include active learning techniques. The ultimate goal is to extend the experience from the two current sections to all five sections of the course.

Firm performance model in small and medium enterprises (SMEs) based on learning orientation and innovation

NASA Astrophysics Data System (ADS)

Lestari, E. R.; Ardianti, F. L.; Rachmawati, L.

2018-03-01

This study investigated the relationship between learning orientation, innovation, and firm performance. A conceptual model and hypothesis were empirically examined using structural equation modelling. The study involved a questionnaire-based survey of owners of small and medium enterprises (SMEs) operating in Batu City, Indonesia. The results showed that both variables of learning orientation and innovation effect positively on firm performance. Additionally, learning orientation has positive effect innovation. This study has implication for SMEs aiming at increasing their firm performance based on learning orientation and innovation capability.

Innovation in Open & Distance Learning: Successful Development of Online and Web-Based Learning.

ERIC Educational Resources Information Center

Lockwood, Fred, Ed.; Gooley, Anne, Ed.

This book contains 19 papers examining innovation in open and distance learning through development of online and World Wide Web-based learning. The following papers are included: "Innovation in Distributed Learning: Creating the Environment" (Fred Lockwood); "Innovation in Open and Distance Learning: Some Lessons from Experience…

Tumor-on-a-chip platforms for assessing nanoparticle-based cancer therapy.

PubMed

Wang, Yimin; Cuzzucoli, Fabio; Escobar, Andres; Lu, Siming; Liang, Liguo; Wang, ShuQi

2018-08-17

Cancer has become the most prevalent cause of deaths, placing a huge economic and healthcare burden worldwide. Nanoparticles (NPs), as a key component of nanomedicine, provide alternative options for promoting the efficacy of cancer therapy. Current conventional cancer models have limitations in predicting the effects of various cancer treatments. To overcome these limitations, biomimetic and novel 'tumor-on-a-chip' platforms have emerged with other innovative biomedical engineering methods that enable the evaluation of NP-based cancer therapy. In this review, we first describe cancer models for evaluation of NP-based cancer therapy techniques, and then present the latest advances in 'tumor-on-a-chip' platforms that can potentially facilitate clinical translation of NP-based cancer therapies.

Final Report: Laser-Based Optical Trap for Remote Sampling of Interplanetary and Atmospheric Particulate Matter

NASA Technical Reports Server (NTRS)

Stysley, Paul

2016-01-01

Applicability to Early Stage Innovation NIAC Cutting edge and innovative technologies are needed to achieve the demanding requirements for NASA origin missions that require sample collection as laid out in the NRC Decadal Survey. This proposal focused on fully understanding the state of remote laser optical trapping techniques for capturing particles and returning them to a target site. In future missions, a laser-based optical trapping system could be deployed on a lander that would then target particles in the lower atmosphere and deliver them to the main instrument for analysis, providing remote access to otherwise inaccessible samples. Alternatively, for a planetary mission the laser could combine ablation and trapping capabilities on targets typically too far away or too hard for traditional drilling sampling systems. For an interstellar mission, a remote laser system could gather particles continuously at a safe distance; this would avoid the necessity of having a spacecraft fly through a target cloud such as a comet tail. If properly designed and implemented, a laser-based optical trapping system could fundamentally change the way scientists designand implement NASA missions that require mass spectroscopy and particle collection.

An intelligent framework for medical image retrieval using MDCT and multi SVM.

PubMed

Balan, J A Alex Rajju; Rajan, S Edward

2014-01-01

Volumes of medical images are rapidly generated in medical field and to manage them effectively has become a great challenge. This paper studies the development of innovative medical image retrieval based on texture features and accuracy. The objective of the paper is to analyze the image retrieval based on diagnosis of healthcare management systems. This paper traces the development of innovative medical image retrieval to estimate both the image texture features and accuracy. The texture features of medical images are extracted using MDCT and multi SVM. Both the theoretical approach and the simulation results revealed interesting observations and they were corroborated using MDCT coefficients and SVM methodology. All attempts to extract the data about the image in response to the query has been computed successfully and perfect image retrieval performance has been obtained. Experimental results on a database of 100 trademark medical images show that an integrated texture feature representation results in 98% of the images being retrieved using MDCT and multi SVM. Thus we have studied a multiclassification technique based on SVM which is prior suitable for medical images. The results show the retrieval accuracy of 98%, 99% for different sets of medical images with respect to the class of image.

New Teaching Techniques.

ERIC Educational Resources Information Center

Health Education (Washington D.C.), 1985

1985-01-01

Health educators have consistently shown creativity in using innovative teaching techniques. Three articles from the past discuss "new" teaching methods: (1) "A Radio Project Teaches Your Class" (Miller); (2) "An Activity Program in Alcohol Education" (Breg); and (3) "Teaching Health Through Pictures" (Haviland). (CB)

A cavitation model based on Eulerian stochastic fields

NASA Astrophysics Data System (ADS)

Magagnato, F.; Dumond, J.

2013-12-01

Non-linear phenomena can often be described using probability density functions (pdf) and pdf transport models. Traditionally the simulation of pdf transport requires Monte-Carlo codes based on Lagrangian "particles" or prescribed pdf assumptions including binning techniques. Recently, in the field of combustion, a novel formulation called the stochastic-field method solving pdf transport based on Eulerian fields has been proposed which eliminates the necessity to mix Eulerian and Lagrangian techniques or prescribed pdf assumptions. In the present work, for the first time the stochastic-field method is applied to multi-phase flow and in particular to cavitating flow. To validate the proposed stochastic-field cavitation model, two applications are considered. Firstly, sheet cavitation is simulated in a Venturi-type nozzle. The second application is an innovative fluidic diode which exhibits coolant flashing. Agreement with experimental results is obtained for both applications with a fixed set of model constants. The stochastic-field cavitation model captures the wide range of pdf shapes present at different locations.

Agent-Based Simulations for Project Management

NASA Technical Reports Server (NTRS)

White, J. Chris; Sholtes, Robert M.

2011-01-01

Currently, the most common approach used in project planning tools is the Critical Path Method (CPM). While this method was a great improvement over the basic Gantt chart technique being used at the time, it now suffers from three primary flaws: (1) task duration is an input, (2) productivity impacts are not considered , and (3) management corrective actions are not included. Today, computers have exceptional computational power to handle complex simulations of task e)(eculion and project management activities (e.g ., dynamically changing the number of resources assigned to a task when it is behind schedule). Through research under a Department of Defense contract, the author and the ViaSim team have developed a project simulation tool that enables more realistic cost and schedule estimates by using a resource-based model that literally turns the current duration-based CPM approach "on its head." The approach represents a fundamental paradigm shift in estimating projects, managing schedules, and reducing risk through innovative predictive techniques.

Entropy-based adaptive attitude estimation

NASA Astrophysics Data System (ADS)

Kiani, Maryam; Barzegar, Aylin; Pourtakdoust, Seid H.

2018-03-01

Gaussian approximation filters have increasingly been developed to enhance the accuracy of attitude estimation in space missions. The effective employment of these algorithms demands accurate knowledge of system dynamics and measurement models, as well as their noise characteristics, which are usually unavailable or unreliable. An innovation-based adaptive filtering approach has been adopted as a solution to this problem; however, it exhibits two major challenges, namely appropriate window size selection and guaranteed assurance of positive definiteness for the estimated noise covariance matrices. The current work presents two novel techniques based on relative entropy and confidence level concepts in order to address the abovementioned drawbacks. The proposed adaptation techniques are applied to two nonlinear state estimation algorithms of the extended Kalman filter and cubature Kalman filter for attitude estimation of a low earth orbit satellite equipped with three-axis magnetometers and Sun sensors. The effectiveness of the proposed adaptation scheme is demonstrated by means of comprehensive sensitivity analysis on the system and environmental parameters by using extensive independent Monte Carlo simulations.

Wavelength-encoded tomography based on optical temporal Fourier transform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Chi; Wong, Kenneth K. Y., E-mail: kywong@eee.hku.hk

We propose and demonstrate a technique called wavelength-encoded tomography (WET) for non-invasive optical cross-sectional imaging, particularly beneficial in biological system. The WET utilizes time-lens to perform the optical Fourier transform, and the time-to-wavelength conversion generates a wavelength-encoded image of optical scattering from internal microstructures, analogous to the interferometery-based imaging such as optical coherence tomography. Optical Fourier transform, in principle, comes with twice as good axial resolution over the electrical Fourier transform, and will greatly simplify the digital signal processing after the data acquisition. As a proof-of-principle demonstration, a 150 -μm (ideally 36 μm) resolution is achieved based on a 7.5-nm bandwidth swept-pump,more » using a conventional optical spectrum analyzer. This approach can potentially achieve up to 100-MHz or even higher frame rate with some proven ultrafast spectrum analyzer. We believe that this technique is innovative towards the next-generation ultrafast optical tomographic imaging application.« less

Rapid wasted-free microfluidic fabrication based on ink-jet approach for microfluidic sensing applications

NASA Astrophysics Data System (ADS)

Jarujareet, Ungkarn; Amarit, Rattasart; Sumriddetchkajorn, Sarun

2016-11-01

Realizing that current microfluidic chip fabrication techniques are time consuming and labor intensive as well as always have material leftover after chip fabrication, this research work proposes an innovative approach for rapid microfluidic chip production. The key idea relies on a combination of a widely-used inkjet printing method and a heat-based polymer curing technique with an electronic-mechanical control, thus eliminating the need of masking and molds compared to typical microfluidic fabrication processes. In addition, as the appropriate amount of polymer is utilized during printing, there is much less amount of material wasted. Our inkjet-based microfluidic printer can print out the desired microfluidic chip pattern directly onto a heated glass surface, where the printed polymer is suddenly cured. Our proof-of-concept demonstration for widely-used single-flow channel, Y-junction, and T-junction microfluidic chips shows that the whole microfluidic chip fabrication process requires only 3 steps with a fabrication time of 6 minutes.

One-Class Classification-Based Real-Time Activity Error Detection in Smart Homes.

PubMed

Das, Barnan; Cook, Diane J; Krishnan, Narayanan C; Schmitter-Edgecombe, Maureen

2016-08-01

Caring for individuals with dementia is frequently associated with extreme physical and emotional stress, which often leads to depression. Smart home technology and advances in machine learning techniques can provide innovative solutions to reduce caregiver burden. One key service that caregivers provide is prompting individuals with memory limitations to initiate and complete daily activities. We hypothesize that sensor technologies combined with machine learning techniques can automate the process of providing reminder-based interventions. The first step towards automated interventions is to detect when an individual faces difficulty with activities. We propose machine learning approaches based on one-class classification that learn normal activity patterns. When we apply these classifiers to activity patterns that were not seen before, the classifiers are able to detect activity errors, which represent potential prompt situations. We validate our approaches on smart home sensor data obtained from older adult participants, some of whom faced difficulties performing routine activities and thus committed errors.

Is There Light at the End of the Tunnel?

ERIC Educational Resources Information Center

Arndt, Nancy Y.

The capacity to produce imagery has been regarded as a powerful agent in the healing process and the use of mental imagery as a healing technique is well established. Freud developed the technique of free association and Jung developed several innovative imagery techniques designed to explore the unconscious. Others have used imagery and…

Hot-wire anemometry in hypersonic helium flow

NASA Technical Reports Server (NTRS)

Wagner, R. D.; Weinstein, L. M.

1974-01-01

Hot-wire anemometry techniques are described that have been developed and used for hypersonic-helium-flow studies. The short run time available dictated certain innovations in applying conventional hot-wire techniques. Some examples are given to show the application of the techniques used. Modifications to conventional equipment are described, including probe modifications and probe heating controls.

Critical incident technique: an innovative participatory approach to examine and document racial disparities in breast cancer healthcare services

PubMed Central

Yonas, Michael A.; Aronson, Robert; Schaal, Jennifer; Eng, Eugenia; Hardy, Christina; Jones, Nora

2013-01-01

Disproportionate and persistent inequities in quality of healthcare have been observed among persons of color in the United States. To understand and ultimately eliminate such inequities, several public health institutions have issued calls for innovative methods and approaches that examine determinants from the social, organizational and public policy contexts to inform the design of systems change interventions. The authors, including academic and community research partners in a community-based participatory research (CBPR) study, reflected together on the use and value of the critical incident technique (CIT) for exploring racial disparities in healthcare for women with breast cancer. Academic and community partners used initial large group discussion involving a large partnership of 35 academic and community researchers guided by principles of CBPR, followed by the efforts of a smaller interdisciplinary manuscript team of academic and community researchers to reflect, document summarize and translate this participatory research process, lessons learned and value added from using the CIT with principles of CBPR and Undoing Racism. The finding of this article is a discussion of the process, strengths and challenges of utilizing CIT with CBPR. The participation of community members at all levels of the research process including development, collection of the data and analysis of the data was enhanced by the CIT process. As the field of CBPR continues to mature, innovative processes which combine the expertise of community and academic partners can enhance the success of such partnerships. This report contributes to existing literature by illustrating a unique and participatory research application of CIT with principles of CBPR and Undoing Racism. Findings highlight the collaborative process used to identify and implement this novel method and the adaptability of this technique in the interdisciplinary exploration of system-level changes to understand and address disparities in breast cancer and cancer care. PMID:24000307

Innovations for Evaluation Research: Multiform Protocols, Visual Analog Scaling, and the Retrospective Pretest-Posttest Design.

PubMed

Chang, Rong; Little, Todd D

2018-06-01

In this article, we review three innovative methods: multiform protocols, visual analog scaling, and the retrospective pretest-posttest design that can be used in evaluation research. These three techniques have been proposed for decades, but unfortunately, they are still not utilized readily in evaluation research. Our goal is to familiarize researchers with these underutilized research techniques that could reduce personnel effort and costs for data collection while producing better inferences for a study. We begin by discussing their applications and special unique features. We then discuss each technique's strengths and limitations and offer practical tips on how to better implement these methods in evaluation research. We then showcase two recent empirical studies that implement these methods in real-world evaluation research applications.

Socio economic community mapping around Dumai Timur (case study: Tanjung Palas Village)

NASA Astrophysics Data System (ADS)

Dilham, Ami; Putra, M. Umar Maya

2018-03-01

This study aimed to analyze the socio economic community mapping around Dumai Timur Sub District with a case study: Tanjung Palas Village. The problem in this research is to analyze community needs and potential contained there. The data used are primary data that have been obtained to do data entry based on the guidance from the actors concerned, there is a transfer in the form of qualitative data into quantitative measurement techniques reference instrument of socio economic mapping activities. From the results of this study indicate that the necessary empowerment of social management in which short-term policy for the addition of water discharge, training on the concept of raising entrepreneurial innovation. For the long term necessary to make a business innovation and sustainability development pattern with operational assistance in the form of seeds, the manufacture of cages and chicken feed.

[Health didactics: undergraduates' nursing representations and the use of an innovative teaching strategy].

PubMed

de Domenico, Edvane Birelo Lopes; Matheus, Maria Clara Cassuli

2009-09-01

This study aimed at analyzing the representations regarding the relationships between Nursing and Education practices, to reveal expectations regarding the course Fundamentals, Methods and Techniques of Teaching and evaluate the use of the Projects Method. Method this is a qualitative evaluation research performed between April and June 2007 with first-year nursing students of a Baccalaureate Degree Program. The data were analyzed based on the Social Representations framework and the constructivist postulates. The students revealed that their learning expectations were related with the contents of didactics, human communication, and the teaching-learning process. The Projects Method was considered capable of providing dynamism, interest towards the content, and the ability to associate theory and practice, in addition to having favored the amplitude and appreciation of the educate/care binomial. In conclusion, health didactics contents are capable of generating students' interest, especially when an innovative methodology is used.

[Current teaching, learning and examination methods in medical education and potential applications in rehabilitative issues].

PubMed

Schwarzkopf, S R; Morfeld, M; Gülich, M; Lay, W; Horn, K; Mau, W

2007-04-01

With introduction of the new Federal Medical Licensing Regulations (Approbationsordnung) in Germany, integrated teaching in "Rehabilitation, Physical Medicine, Naturopathic Treatment" (Querschnittsbereich Q12) has become obligatory for the first time. Furthermore, the new Regulations require the medical faculties in Germany to realize an innovative didactic orientation in teaching. This paper provides an overview of recent applications of teaching techniques and examination methods in medical education with special consideration of the new integrated course Q12 and further teaching methods related to rehabilitative issues. Problem-oriented learning (POL), problem-based learning (PBL), bedside teaching, eLearning, and the examination methods Objective Structured Clinical Examination (OSCE) and Triple Jump are in the focus. This overview is intended as the basis for subsequent publications of the Commission for Undergraduate and Postgraduate Training of the German Society of Rehabilitation Science (DGRW), which will present examples of innovative teaching material.

Innovative approaches for converting a wood hydrolysate to high-quality barrier coatings.

PubMed

Ryberg, Yingzhi Zhu; Edlund, Ulrica; Albertsson, Ann-Christine

2013-08-28

An advanced approach for the efficient and controllable production of softwood hydrolysate-based coatings with excellent oxygen-barrier performance is presented. An innovative conversion of the spray-drying technique into a coating applicator process allowed for a fast and efficient coating process requiring solely aqueous solutions of softwood hydrolysate, even without additives. Compared to analogous coatings prepared by manual application, the spray-drying produced coatings were more homogeneous and smooth, and they adhered more strongly to the substrate. The addition of glyoxal to the aqueous softwood hydrolysate solutions prior to coating formation allowed for hemicellulose cross-linking, which improved both the mechanical integrity and the oxygen-barrier performance of the coatings. A real-time scanning electron microscopy imaging assessment of the tensile deformation of the coatings allowed for a deeper understanding of the ability of the coating layer itself to withstand stress as well as the coating-to-substrate adhesion.

High-quality GaN epitaxially grown on Si substrate with serpentine channels

NASA Astrophysics Data System (ADS)

Wei, Tiantian; Zong, Hua; Jiang, Shengxiang; Yang, Yue; Liao, Hui; Xie, Yahong; Wang, Wenjie; Li, Junze; Tang, Jun; Hu, Xiaodong

2018-06-01

A novel serpentine-channeled mask was introduced to Si substrate for low-dislocation GaN epitaxial growth and the fully coalesced GaN film on the masked Si substrate was achieved for the first time. Compared with the epitaxial lateral overgrowth (ELOG) growth method, this innovative mask only requires one-step epitaxial growth of GaN which has only one high-dislocation region per mask opening. This new growth method can effectively reduce dislocation density, thus improving the quality of GaN significantly. High-quality GaN with low dislocation density ∼2.4 × 107 cm-2 was obtained, which accounted for about eighty percent of the GaN film in area. This innovative technique is promising for the growth of high-quality GaN templates and the subsequent fabrication of high-performance GaN-based devices like transistors, laser diodes (LDs), and light-emitting diodes (LEDs) on Si substrate.

Computing in Hydraulic Engineering Education

NASA Astrophysics Data System (ADS)

Duan, J. G.

2011-12-01

Civil engineers, pioneers of our civilization, are rarely perceived as leaders and innovators in modern society because of retardations in technology innovation. This crisis has resulted in the decline of the prestige of civil engineering profession, reduction of federal funding on deteriorating infrastructures, and problems with attracting the most talented high-school students. Infusion of cutting-edge computer technology and stimulating creativity and innovation therefore are the critical challenge to civil engineering education. To better prepare our graduates to innovate, this paper discussed the adaption of problem-based collaborative learning technique and integration of civil engineering computing into a traditional civil engineering curriculum. Three interconnected courses: Open Channel Flow, Computational Hydraulics, and Sedimentation Engineering, were developed with emphasis on computational simulations. In Open Channel flow, the focuses are principles of free surface flow and the application of computational models. This prepares students to the 2nd course, Computational Hydraulics, that introduce the fundamental principles of computational hydraulics, including finite difference and finite element methods. This course complements the Open Channel Flow class to provide students with in-depth understandings of computational methods. The 3rd course, Sedimentation Engineering, covers the fundamentals of sediment transport and river engineering, so students can apply the knowledge and programming skills gained from previous courses to develop computational models for simulating sediment transport. These courses effectively equipped students with important skills and knowledge to complete thesis and dissertation research.

Quadrature demodulation based circuit implementation of pulse stream for ultrasonic signal FRI sparse sampling

NASA Astrophysics Data System (ADS)

Shoupeng, Song; Zhou, Jiang

2017-03-01

Converting ultrasonic signal to ultrasonic pulse stream is the key step of finite rate of innovation (FRI) sparse sampling. At present, ultrasonic pulse-stream-forming techniques are mainly based on digital algorithms. No hardware circuit that can achieve it has been reported. This paper proposes a new quadrature demodulation (QD) based circuit implementation method for forming an ultrasonic pulse stream. Elaborating on FRI sparse sampling theory, the process of ultrasonic signal is explained, followed by a discussion and analysis of ultrasonic pulse-stream-forming methods. In contrast to ultrasonic signal envelope extracting techniques, a quadrature demodulation method (QDM) is proposed. Simulation experiments were performed to determine its performance at various signal-to-noise ratios (SNRs). The circuit was then designed, with mixing module, oscillator, low pass filter (LPF), and root of square sum module. Finally, application experiments were carried out on pipeline sample ultrasonic flaw testing. The experimental results indicate that the QDM can accurately convert ultrasonic signal to ultrasonic pulse stream, and reverse the original signal information, such as pulse width, amplitude, and time of arrival. This technique lays the foundation for ultrasonic signal FRI sparse sampling directly with hardware circuitry.

CALM: Complex Adaptive System (CAS)-Based Decision Support for Enabling Organizational Change

NASA Astrophysics Data System (ADS)

Adler, Richard M.; Koehn, David J.

Guiding organizations through transformational changes such as restructuring or adopting new technologies is a daunting task. Such changes generate workforce uncertainty, fear, and resistance, reducing morale, focus and performance. Conventional project management techniques fail to mitigate these disruptive effects, because social and individual changes are non-mechanistic, organic phenomena. CALM (for Change, Adaptation, Learning Model) is an innovative decision support system for enabling change based on CAS principles. CALM provides a low risk method for validating and refining change strategies that combines scenario planning techniques with "what-if" behavioral simulation. In essence, CALM "test drives" change strategies before rolling them out, allowing organizations to practice and learn from virtual rather than actual mistakes. This paper describes the CALM modeling methodology, including our metrics for measuring organizational readiness to respond to change and other major CALM scenario elements: prospective change strategies; alternate futures; and key situational dynamics. We then describe CALM's simulation engine for projecting scenario outcomes and its associated analytics. CALM's simulator unifies diverse behavioral simulation paradigms including: adaptive agents; system dynamics; Monte Carlo; event- and process-based techniques. CALM's embodiment of CAS dynamics helps organizations reduce risk and improve confidence and consistency in critical strategies for enabling transformations.

SME 2.0: Roadmap towards Web 2.0-Based Open Innovation in SME-Networks - A Case Study Based Research Framework

NASA Astrophysics Data System (ADS)

Lindermann, Nadine; Valcárcel, Sylvia; Schaarschmidt, Mario; von Kortzfleisch, Harald

Small- and medium sized enterprises (SMEs) are of high social and economic importance since they represent 99% of European enterprises. With regard to their restricted resources, SMEs are facing a limited capacity for innovation to compete with new challenges in a complex and dynamic competitive environment. Given this context, SMEs need to increasingly cooperate to generate innovations on an extended resource base. Our research project focuses on the aspect of open innovation in SME-networks enabled by Web 2.0 applications and referring to innovative solutions of non-competitive daily life problems. Examples are industrial safety, work-life balance issues or pollution control. The project raises the question whether the use of Web 2.0 applications can foster the exchange of creativity and innovative ideas within a network of SMEs and hence catalyze new forms of innovation processes among its participants. Using Web 2.0 applications within SMEs implies consequently breaking down innovation processes to employees’ level and thus systematically opening up a heterogeneous and broader knowledge base to idea generation. In this paper we address first steps on a roadmap towards Web 2.0-based open innovation processes within SME-networks. It presents a general framework for interaction activities leading to open innovation and recommends a regional marketplace as a viable, trust-building driver for further collaborative activities. These findings are based on field research within a specific SME-network in Rhineland-Palatinate Germany, the “WirtschaftsForum Neuwied e.V.”, which consists of roughly 100 heterogeneous SMEs employing about 8,000 workers.

Precision Time Protocol-Based Trilateration for Planetary Navigation

NASA Technical Reports Server (NTRS)

Murdock, Ron

2015-01-01

Progeny Systems Corporation has developed a high-fidelity, field-scalable, non-Global Positioning System (GPS) navigation system that offers precision localization over communications channels. The system is bidirectional, providing position information to both base and mobile units. It is the first-ever wireless use of the Institute of Electrical and Electronics Engineers (IEEE) Precision Time Protocol (PTP) in a bidirectional trilateration navigation system. The innovation provides a precise and reliable navigation capability to support traverse-path planning systems and other mapping applications, and it establishes a core infrastructure for long-term lunar and planetary occupation. Mature technologies are integrated to provide navigation capability and to support data and voice communications on the same network. On Earth, the innovation is particularly well suited for use in unmanned aerial vehicles (UAVs), as it offers a non-GPS precision navigation and location service for use in GPS-denied environments. Its bidirectional capability provides real-time location data to the UAV operator and to the UAV. This approach optimizes assisted GPS techniques and can be used to determine the presence of GPS degradation, spoofing, or jamming.

The innovative landscape design on the old dense area based on community participation

NASA Astrophysics Data System (ADS)

Soemardiono, B.; Rachmawati, M.

2018-03-01

Kembang Jepun area on the east side of the Kali Mas extends to the edge of the river. Along with the development of the city, Kembang Jepun denser, and these districts are facing some issues with limited landscape elements such as land and water elements, lacking in vegetation element in the settlement and services area, and non-optimal streetscape arrangement in the historic town and make the old city less attractive. In the other side, this historic section of the city has the great potential to be developed in order to support the economic developments of the city. Large Scale Intervention is the method of collaboration in developing area which possesses the meaning in the sustainable urban development. So community involvement is an important key factor in the design process and implementation as well as the type of participation and the technique of the process. The expected result of this paper is how to develop the innovative landscape design in the developing old dense area of Kembang Jepun based on community participation.

Selecting for creativity and innovation potential: implications for practice in healthcare education.

PubMed

Patterson, Fiona; Zibarras, Lara Dawn

2017-05-01

The ability to innovate is an important requirement in many organisations. Despite this pressing need, few selection systems in healthcare focus on identifying the potential for creativity and innovation and so this area has been vastly under-researched. As a first step towards understanding how we might select for creativity and innovation, this paper explores the use of a trait-based measure of creativity and innovation potential, and evaluates its efficacy for use in selection for healthcare education. This study uses a sample of 188 postgraduate physicians applying for education and training in UK General Practice. Participants completed two questionnaires (a trait-based measure of creativity and innovation, and a measure of the Big Five personality dimensions) and were also rated by assessors on creative problem solving measured during a selection centre. In exploring the construct validity of the trait-based measure of creativity and innovation, our research clarifies the associations between personality, and creativity and innovation. In particular, our study highlights the importance of motivation in the creativity and innovation process. Results also suggest that Openness to Experience is positively related to creativity and innovation whereas some aspects of Conscientiousness are negatively associated with creativity and innovation. Results broadly support the utility of using a trait-based measure of creativity and innovation in healthcare selection processes, although practically this may be best delivered as part of an interview process, rather than as a screening tool. Findings are discussed in relation to broader implications for placing more priority on creativity and innovation as selection criteria within healthcare education and training in future.

Human factors considerations for training astronauts to function effectively in multiple environments

NASA Technical Reports Server (NTRS)

Cohen, Malcolm M.

1991-01-01

This paper reviews some of the basic issues involved in training individuals to function appropriately under the several conditions that comprise the aerospace environment. The topic of transfer of training is examined in some detail, and the use of high-fidelity simulators in various training programs is discussed. Both current and classical techniques used to train astronauts are noted, and some relatively new and innovative training techniques and methods are described. Particularly, the paper discusses an important aspect of functioning appropriately in a given environment that is based on how well the operator calibrates his motor activity for that specific environment. The role of motor-sensory feedback for the acquisition of motor skills is discussed in the context of training.

Nonlinear Acoustic and Ultrasonic NDT of Aeronautical Components

NASA Astrophysics Data System (ADS)

Van Den Abeele, Koen; Katkowski, Tomasz; Mattei, Christophe

2006-05-01

In response to the demand for innovative microdamage inspection systems, with high sensitivity and undoubted accuracy, we are currently investigating the use and robustness of several acoustic and ultrasonic NDT techniques based on Nonlinear Elastic Wave Spectroscopy (NEWS) for the characterization of microdamage in aeronautical components. In this report, we illustrate the results of an amplitude dependent analysis of the resonance behaviour, both in time (signal reverberation) and in frequency (sweep) domain. The technique is applied to intact and damaged samples of Carbon Fiber Reinforced Plastics (CFRP) composites after thermal loading or mechanical fatigue. The method shows a considerable gain in sensitivity and an incontestable interpretation of the results for nonlinear signatures in comparison with the linear characteristics. For highly fatigued samples, slow dynamical effects are observed.

Fractional CO2 resurfacing: has it replaced ablative resurfacing techniques?

PubMed

Duplechain, Jesse Kevin

2013-05-01

The author uses the pulsed ablative CO2 laser regularly for skin rejuvenation. This decision is based on the gold standard status of the CO2 modality and an innovative aftercare treatment shown in the author's practice to greatly reduce the complications of ablative pulsed CO2 laser treatment. Depending on the patient and the severity of the skin condition, the author customizes each treatment, which may also include fractional CO2 lasers, fat grafting, facelifting, or any combination of these techniques. This article presents a detailed description of the evolution of skin rejuvenation with lasers and the current role of lasers as an adjunct to face and necklift surgery. Copyright © 2013 Elsevier Inc. All rights reserved.

1. Innovative Relaxor-Based PiezoCrystals: Phase Diagrams, Crystal Growth, Domain Structures and Electric Properties. 2. Piezo- and Ferroelectric Materials Based on Morphotropic Phase Boundary Synthesis, Characterization and Structure - Property Relations

DTIC Science & Technology

2006-03-31

crystals by the flux method and modified Bridgman technique, the growth results were hardly reproducible, and the quality of the crystals was still a serious... growth . 2.2.1.2.2) Solution Bridgman Growth A modified Bridgman method using excess of PbO as solvent was developed for the growth of PZNT91/9 crystals ...of growth , the grown crystal can be rotated via the A120 3 rod which was driven by a motor at a speed of 0 to 30 rmp. Figure 15(b) gives the

Road sign recognition using Viapix module and correlation

NASA Astrophysics Data System (ADS)

Ouerhani, Y.; Desthieux, M.; Alfalou, A.

2015-03-01

In this paper, we propose and validate a new system used to explore road assets. In this work we are interested on the vertical road signs. To do this, we are based on the combination of road signs detection, recognition and identification using data provides by sensors. The proposed approach consists on using panoramic views provided by the innovative device, VIAPIX®1, developed by our company ACTRIS2. We are based also on the optimized correlation technique for road signs recognition and identification on pictures. Obtained results shows the interest on using panoramic views compared to results obtained using images provided using only one camera.

Turning Avatar into Realistic Human Expression Using Linear and Bilinear Interpolations

NASA Astrophysics Data System (ADS)

Hazim Alkawaz, Mohammed; Mohamad, Dzulkifli; Rehman, Amjad; Basori, Ahmad Hoirul

2014-06-01

The facial animation in term of 3D facial data has accurate research support of the laser scan and advance 3D tools for complex facial model production. However, the approach still lacks facial expression based on emotional condition. Though, facial skin colour is required to offers an effect of facial expression improvement, closely related to the human emotion. This paper presents innovative techniques for facial animation transformation using the facial skin colour based on linear interpolation and bilinear interpolation. The generated expressions are almost same to the genuine human expression and also enhance the facial expression of the virtual human.

An evolution in interdisciplinary competencies to prevent and manage patient violence.

PubMed

Morton, Paula G

2002-01-01

Patient violence is a growing problem in healthcare institutions. Incidents of violence lead to injuries and increased operating costs. An innovative organizational approach to this problem is inclusion of interdisciplinary competency-based staff education and practice, as a key component of a comprehensive violence prevention program.Interdisciplinary competencies include a variety of behavioral responses, aimed at prevention, environmental, interpersonal, and physical interventions and postvention techniques for aggression and violence. Methods to maintain, monitor, document, and improve staff performance and skills are delineated. Organizational investment in such interdisciplinary competency-based education and practice evolves over time. Results include fewer incidents and injuries and enhanced interdisciplinary cooperation.

Scaling up Evidence-Based Practices: Strategies from Investing in Innovation (i3)

ERIC Educational Resources Information Center

DeWire, Tom; McKithen, Clarissa; Carey, Rebecca

2017-01-01

What can the Investing in Innovation (i3) grantees tell us about scaling innovative educational practices? The newly released white paper "Scaling Up Evidence-Based Practices: Strategies from Investing in Innovation (i3)" captures the experiences of nine grantees whose projects collectively have reached over 1.2 million students across…

Ultrasonic technique for inspection of GPHS capsule girth weld integrity

NASA Astrophysics Data System (ADS)

Placr, Arnost

1993-05-01

An innovative nondestructive examination (NDE) technique for the inspection of integrity of General Purpose Heat Source (GPHS) capsule girth welds was developed employing a Lamb wave as the mode of the sound propagation. Reliability of the Lamb wave technique was tested on GPHS capsules using plutonium pallet simulators. All ten capsules, which were previously rejected, passed ultrasonic (UT) inspection using the Lamb wave technique.

Research Methods in Education

ERIC Educational Resources Information Center

Check, Joseph; Schutt, Russell K.

2011-01-01

"Research Methods in Education" introduces research methods as an integrated set of techniques for investigating questions about the educational world. This lively, innovative text helps students connect technique and substance, appreciate the value of both qualitative and quantitative methodologies, and make ethical research decisions.…

Innovation in Health Care Delivery.

PubMed

Sharan, Alok D; Schroeder, Gregory D; West, Michael E; Vaccaro, Alexander R

2016-02-01

As reimbursement transitions from a volume-based to a value-based system, innovation in health care delivery will be needed. The process of innovation begins with framing the problem that needs to be solved along with the strategic vision that has to be achieved. Similar to scientific testing, a hypothesis is generated for a new solution to a problem. Innovation requires conducting a disciplined form of experimentation and then learning from the process. This manuscript will discuss the different types of innovation, and the key steps necessary for successful innovation in the health care field.

Innovative technologies and social inequalities in health: A scoping review of the literature

PubMed Central

Jensen, Magnus Rom; Solhaug, Solvor; Krokstad, Steinar

2018-01-01

The aim of this study was to systematically review the range, nature, and extent of current research activity exploring the influence of innovative health-related technologies on social inequalities in health, with specific focus on a deeper understanding of the variables used to measure this connection and the pathways leading to the (re)production of inequalities. A review process was conducted, based on scoping review techniques, searching literature published from January 1, 1996 to November 25, 2016 using MEDLINE, Scopus, and ISI web of science. Search, sorting, and data extraction processes were conducted by a team of researchers and experts using a dynamic, reflexive examination process. Of 4139 studies collected from the search process, a total of 33 were included in the final analysis. Results of this study include the classification of technologies based on how these technologies are accessed and used by end users. In addition to the factors and mechanisms that influence unequal access to technologies, the results of this study highlight the importance of variations in use that importantly shape social inequalities in health. Additionally, focus on health care services technologies must be accompanied by investigating emerging technologies influencing healthy lifestyle, genomics, and personalized devices in health. Findings also suggest that choosing one measure of social position over another has important implications for the interpretation of research results. Furthermore, understanding the pathways through which various innovative health technologies reduce or (re)produce social inequalities in health is context dependent. In order to better understand social inequalities in health, these contextual variations draw attention to the need for critical distinctions between technologies based on how these various technologies are accessed and used. The results of this study provide a comprehensive starting point for future research to further investigate how innovative technologies may influence the unequal distribution of health as a human right. PMID:29614114

Innovative technologies and social inequalities in health: A scoping review of the literature.

PubMed

Weiss, Daniel; Rydland, Håvard T; Øversveen, Emil; Jensen, Magnus Rom; Solhaug, Solvor; Krokstad, Steinar

2018-01-01

The aim of this study was to systematically review the range, nature, and extent of current research activity exploring the influence of innovative health-related technologies on social inequalities in health, with specific focus on a deeper understanding of the variables used to measure this connection and the pathways leading to the (re)production of inequalities. A review process was conducted, based on scoping review techniques, searching literature published from January 1, 1996 to November 25, 2016 using MEDLINE, Scopus, and ISI web of science. Search, sorting, and data extraction processes were conducted by a team of researchers and experts using a dynamic, reflexive examination process. Of 4139 studies collected from the search process, a total of 33 were included in the final analysis. Results of this study include the classification of technologies based on how these technologies are accessed and used by end users. In addition to the factors and mechanisms that influence unequal access to technologies, the results of this study highlight the importance of variations in use that importantly shape social inequalities in health. Additionally, focus on health care services technologies must be accompanied by investigating emerging technologies influencing healthy lifestyle, genomics, and personalized devices in health. Findings also suggest that choosing one measure of social position over another has important implications for the interpretation of research results. Furthermore, understanding the pathways through which various innovative health technologies reduce or (re)produce social inequalities in health is context dependent. In order to better understand social inequalities in health, these contextual variations draw attention to the need for critical distinctions between technologies based on how these various technologies are accessed and used. The results of this study provide a comprehensive starting point for future research to further investigate how innovative technologies may influence the unequal distribution of health as a human right.

INNOVATIVE EASY-TO-USE PASSIVE TECHNIQUE FOR 222RN AND 220RN DECAY PRODUCT DETECTION.

PubMed

Mishra, Rosaline; Rout, R; Prajith, R; Jalalluddin, S; Sapra, B K; Mayya, Y S

2016-10-01

The decay products of radon and thoron are essentially the radioisotopes of polonium, bismuth and lead, and are solid particulates, which deposit in different parts of the respiratory tract upon inhalation, subsequently emitting high-energy alpha particles upon their radioactive decay. Development of passive deposition-based direct progeny sensors known as direct radon and thoron progeny sensors have provided an easy-to-use technique for time-integrated measurements of the decay products only. These dosemeters are apt for large-scale population dosimetry to assign inhalation doses to the public. The paper gives an insight into the technique, the calibration, comparison with the prevalently used active grab filter paper sampling technique, alpha track diameter analysis in these progeny sensors, progeny deposition velocity measurements carried out using these detector systems in the indoor as well as outdoor environment, and applications of these sensors for time-integrated unattached fraction estimation. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

De-embedding technique for accurate modeling of compact 3D MMIC CPW transmission lines

NASA Astrophysics Data System (ADS)

Pohan, U. H.; KKyabaggu, P. B.; Sinulingga, E. P.

2018-02-01

Requirement for high-density and high-functionality microwave and millimeter-wave circuits have led to the innovative circuit architectures such as three-dimensional multilayer MMICs. The major advantage of the multilayer techniques is that one can employ passive and active components based on CPW technology. In this work, MMIC Coplanar Waveguide(CPW)components such as Transmission Line (TL) are modeled in their 3D layouts. Main characteristics of CPWTL suffered from the probe pads’ parasitic and resonant frequency effects have been studied. By understanding the parasitic effects, then the novel de-embedding technique are developed accurately in order to predict high frequency characteristics of the designed MMICs. The novel de-embedding technique has shown to be critical in reducing the probe pad parasitic significantly from the model. As results, high frequency characteristics of the designed MMICs have been presented with minimumparasitic effects of the probe pads. The de-embedding process optimises the determination of main characteristics of Compact 3D MMIC CPW transmission lines.

Biosensors and their applications in detection of organophosphorus pesticides in the environment.

PubMed

Hassani, Shokoufeh; Momtaz, Saeideh; Vakhshiteh, Faezeh; Maghsoudi, Armin Salek; Ganjali, Mohammad Reza; Norouzi, Parviz; Abdollahi, Mohammad

2017-01-01

This review discusses the past and recent advancements of biosensors focusing on detection of organophosphorus pesticides (OPs) due to their exceptional use during the last decades. Apart from agricultural benefits, OPs also impose adverse toxicological effects on animal and human population. Conventional approaches such as chromatographic techniques used for pesticide detection are associated with several limitations. A biosensor technology is unique due to the detection sensitivity, selectivity, remarkable performance capabilities, simplicity and on-site operation, fabrication and incorporation with nanomaterials. This study also provided specifications of the most OPs biosensors reported until today based on their transducer system. In addition, we highlighted the application of advanced complementary materials and analysis techniques in OPs detection systems. The availability of these new materials associated with new sensing techniques has led to introduction of easy-to-use analytical tools of high sensitivity and specificity in the design and construction of OPs biosensors. In this review, we elaborated the achievements in sensing systems concerning innovative nanomaterials and analytical techniques with emphasis on OPs.

Electrical characterization of a Mapham inverter using pulse testing techniques

NASA Technical Reports Server (NTRS)

Baumann, E. D.; Myers, I. T.; Hammond, A. N.

1990-01-01

Electric power requirements for aerospace missions have reached megawatt power levels. Within the next few decades, it is anticipated that a manned lunar base, interplanetary travel, and surface exploration of the Martian surface will become reality. Several research and development projects aimed at demonstrating megawatt power level converters for space applications are currently underway at the NASA Lewis Research Center. Innovative testing techniques will be required to evaluate the components and converters, when developed, at their rated power in the absence of costly power sources, loads, and cooling systems. Facilities capable of testing these components and systems at full power are available, but their use may be cost prohibitive. The use of a multiple pulse testing technique is proposed to determine the electrical characteristics of large megawatt level power systems. Characterization of a Mapham inverter is made using the proposed technique and conclusions are drawn concerning its suitability as an experimental tool to evaluate megawatt level power systems.

Magneto-optical imaging technique for hostile environments: The ghost imaging approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meda, A.; Caprile, A.; Avella, A.

2015-06-29

In this paper, we develop an approach to magneto optical imaging (MOI), applying a ghost imaging (GI) protocol to perform Faraday microscopy. MOI is of the utmost importance for the investigation of magnetic properties of material samples, through Weiss domains shape, dimension and dynamics analysis. Nevertheless, in some extreme conditions such as cryogenic temperatures or high magnetic field applications, there exists a lack of domain images due to the difficulty in creating an efficient imaging system in such environments. Here, we present an innovative MOI technique that separates the imaging optical path from the one illuminating the object. The techniquemore » is based on thermal light GI and exploits correlations between light beams to retrieve the image of magnetic domains. As a proof of principle, the proposed technique is applied to the Faraday magneto-optical observation of the remanence domain structure of an yttrium iron garnet sample.« less

Technological innovation in video-assisted thoracic surgery.

PubMed

Özyurtkan, Mehmet Oğuzhan; Kaba, Erkan; Toker, Alper

2017-01-01

The popularity of video-assisted thoracic surgery (VATS) which increased worldwide due to the recent innovations in thoracic surgical technics, equipment, electronic devices that carry light and vision and high definition monitors. Uniportal VATS (UVATS) is disseminated widely, creating a drive to develop new techniques and instruments, including new graspers and special staplers with more angulation capacities. During the history of VATS, the classical 10 mm 0° or 30° rigid rod lens system, has been replaced by new thoracoscopes providing a variable angle technology and allowing 0° and 120° range of vision. Besides, the tip of these novel thoracoscopes can be positioned away from the operating side minimize fencing with other thoracoscopic instruments. The curved-tip stapler technology, and better designed endostaplers helped better dissection, precision of control, more secure staple lines. UVATS also contributed to the development of embryonic natural orifice transluminal endoscopic surgery. Three-dimensional VATS systems facilitated faster and more accurate grasping, suturing, and dissection of the tissues by restoring natural 3D vision and the perception of depth. Another innovation in VATS is the energy-based coagulative and tissue fusion technology which may be an alternative to endostaplers.

Innovative Design and Performance Evaluation of Bionic Imprinting Toothed Wheel.

PubMed

Zhang, Zhihong; Wang, Xiaoyang; Tong, Jin; Stephen, Carr

2018-01-01

A highly efficient soil-burrowing dung beetle possesses an intricate outer contour curve on its foreleg end-tooth. This study was carried out based on evidence that this special outer contour curve has the potential of reducing soil penetration resistance and could enhance soil-burrowing efficiency. A toothed wheel is a typical agricultural implement for soil imprinting, to increase its working efficiency; the approach of the bionic geometrical structure was utilized to optimize the innovative shape of imprinting toothed wheel. Characteristics in the dung beetle's foreleg end-tooth were extracted and studied by the edge detection technique. Then, this special outer contour curve was modeled by a nine-order polynomial function and used for the innovative design of imprinting the tooth's cutting edge. Both the conventional and bionic teeth were manufactured, and traction tests in a soil bin were conducted. Taking required draft force and volume of imprinted microbasin as the evaluating indexes, operating efficiency and quality of different toothed wheels were compared and investigated. Results indicate that compared with the conventional toothed wheel, a bionic toothed wheel possesses a better forward resistance reduction property against soil and, meanwhile, can enhance the quality of soil imprinting by increasing the volume of the created micro-basin.

Innovative design method of automobile profile based on Fourier descriptor

NASA Astrophysics Data System (ADS)

Gao, Shuyong; Fu, Chaoxing; Xia, Fan; Shen, Wei

2017-10-01

Aiming at the innovation of the contours of automobile side, this paper presents an innovative design method of vehicle side profile based on Fourier descriptor. The design flow of this design method is: pre-processing, coordinate extraction, standardization, discrete Fourier transform, simplified Fourier descriptor, exchange descriptor innovation, inverse Fourier transform to get the outline of innovative design. Innovative concepts of the innovative methods of gene exchange among species and the innovative methods of gene exchange among different species are presented, and the contours of the innovative design are obtained separately. A three-dimensional model of a car is obtained by referring to the profile curve which is obtained by exchanging xenogeneic genes. The feasibility of the method proposed in this paper is verified by various aspects.

Outside-In Systems Pharmacology Combines Innovative Computational Methods With High-Throughput Whole Vertebrate Studies.

PubMed

Schulthess, Pascal; van Wijk, Rob C; Krekels, Elke H J; Yates, James W T; Spaink, Herman P; van der Graaf, Piet H

2018-04-25

To advance the systems approach in pharmacology, experimental models and computational methods need to be integrated from early drug discovery onward. Here, we propose outside-in model development, a model identification technique to understand and predict the dynamics of a system without requiring prior biological and/or pharmacological knowledge. The advanced data required could be obtained by whole vertebrate, high-throughput, low-resource dose-exposure-effect experimentation with the zebrafish larva. Combinations of these innovative techniques could improve early drug discovery. © 2018 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.

Statistical synthesis of contextual knowledge to increase the effectiveness of theory-based behaviour change interventions.

PubMed

Hanbury, Andria; Thompson, Carl; Mannion, Russell

2011-07-01

Tailored implementation strategies targeting health professionals' adoption of evidence-based recommendations are currently being developed. Research has focused on how to select an appropriate theoretical base, how to use that theoretical base to explore the local context, and how to translate theoretical constructs associated with the key factors found to influence innovation adoption into feasible and tailored implementation strategies. The reasons why an intervention is thought not to have worked are often cited as being: inappropriate choice of theoretical base; unsystematic development of the implementation strategies; and a poor evidence base to guide the process. One area of implementation research that is commonly overlooked is how to synthesize the data collected in a local context in order to identify what factors to target with the implementation strategies. This is suggested to be a critical process in the development of a theory-based intervention. The potential of multilevel modelling techniques to synthesize data collected at different hierarchical levels, for example, individual attitudes and team level variables, is discussed. Future research is needed to explore further the potential of multilevel modelling for synthesizing contextual data in implementation studies, as well as techniques for synthesizing qualitative and quantitative data.

A Systems Approach to Healthcare Innovation Using the MIT Hacking Medicine Model.

PubMed

Gubin, Tatyana A; Iyer, Hari P; Liew, Shirlene N; Sarma, Aartik; Revelos, Alex; Ribas, João; Movassaghi, Babak; Chu, Zen M; Khalid, Ayesha N; Majmudar, Maulik D; Lee, Christopher Xiang

2017-07-26

MIT Hacking Medicine is a student, academic, and community-led organization that uses systems-oriented "healthcare hacking" to address challenges around innovation in healthcare. The group has organized more than 80 events around the world that attract participants with diverse backgrounds. These participants are trained to address clinical needs from the perspective of multiple stakeholders and emphasize utility and implementation viability of proposed solutions. We describe the MIT Hacking Medicine model as a potential method to integrate collaboration and training in rapid innovation techniques into academic medical centers. Built upon a systems approach to healthcare innovation, the time-compressed but expertly guided nature of the events could enable more widely accessible preliminary training in systems-level innovation methodology, as well as creating a structured opportunity for interdisciplinary congregation and collaboration. Copyright © 2017 Elsevier Inc. All rights reserved.

The Future of Pharmaceutical Manufacturing Sciences

PubMed Central

2015-01-01

The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial‐scale manufacturing of complex drug delivery systems (DDSs) using the existing technologies is challenging. This review covers important elements of manufacturing sciences, beginning with risk management strategies and design of experiments (DoE) techniques. Experimental techniques should, where possible, be supported by computational approaches. With that regard, state‐of‐art mechanistic process modeling techniques are described in detail. Implementation of materials science tools paves the way to molecular‐based processing of future DDSs. A snapshot of some of the existing tools is presented. Additionally, general engineering principles are discussed covering process measurement and process control solutions. Last part of the review addresses future manufacturing solutions, covering continuous processing and, specifically, hot‐melt processing and printing‐based technologies. Finally, challenges related to implementing these technologies as a part of future health care systems are discussed. © 2015 The Authors. Journal of Pharmaceutical Sciences published by Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 104:3612–3638, 2015 PMID:26280993

A combined qualitative-quantitative approach for the identification of highly co-creative technology-driven firms

NASA Astrophysics Data System (ADS)

Milyakov, Hristo; Tanev, Stoyan; Ruskov, Petko

2011-03-01

Value co-creation, is an emerging business and innovation paradigm, however, there is not enough clarity on the distinctive characteristics of value co-creation as compared to more traditional value creation approaches. The present paper summarizes the results from an empirically-derived research study focusing on the development of a systematic procedure for the identification of firms that are active in value co-creation. The study is based on a sample 273 firms that were selected for being representative of the breadth of their value co-creation activities. The results include: i) the identification of the key components of value co-creation based on a research methodology using web search and Principal Component Analysis techniques, and ii) the comparison of two different classification techniques identifying the firms with the highest degree of involvement in value co-creation practices. To the best of our knowledge this is the first study using sophisticated data collection techniques to provide a classification of firms according to the degree of their involvement in value co-creation.

The Future of Pharmaceutical Manufacturing Sciences.

PubMed

Rantanen, Jukka; Khinast, Johannes

2015-11-01

The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial-scale manufacturing of complex drug delivery systems (DDSs) using the existing technologies is challenging. This review covers important elements of manufacturing sciences, beginning with risk management strategies and design of experiments (DoE) techniques. Experimental techniques should, where possible, be supported by computational approaches. With that regard, state-of-art mechanistic process modeling techniques are described in detail. Implementation of materials science tools paves the way to molecular-based processing of future DDSs. A snapshot of some of the existing tools is presented. Additionally, general engineering principles are discussed covering process measurement and process control solutions. Last part of the review addresses future manufacturing solutions, covering continuous processing and, specifically, hot-melt processing and printing-based technologies. Finally, challenges related to implementing these technologies as a part of future health care systems are discussed. © 2015 The Authors. Journal of Pharmaceutical Sciences published by Wiley Periodicals, Inc. and the American Pharmacists Association.

Introducing the Big Knowledge to Use (BK2U) challenge

PubMed Central

Perl, Yehoshua; Geller, James; Halper, Michael; Ochs, Christopher; Zheng, Ling; Kapusnik-Uner, Joan

2016-01-01

The purpose of the Big Data to Knowledge (BD2K) initiative is to develop methods for discovering new knowledge from large amounts of data. However, if the resulting knowledge is so large that it resists comprehension, referred to here as Big Knowledge (BK), how can it be used properly and creatively? We call this secondary challenge, Big Knowledge to Use (BK2U). Without a high-level mental representation of the kinds of knowledge in a BK knowledgebase, effective or innovative use of the knowledge may be limited. We describe summarization and visualization techniques that capture the big picture of a BK knowledgebase, possibly created from Big Data. In this research, we distinguish between assertion BK and rule-based BK and demonstrate the usefulness of summarization and visualization techniques of assertion BK for clinical phenotyping. As an example, we illustrate how a summary of many intracranial bleeding concepts can improve phenotyping, compared to the traditional approach. We also demonstrate the usefulness of summarization and visualization techniques of rule-based BK for drug–drug interaction discovery. PMID:27750400

Application of additive laser technologies in the gas turbine blades design process

NASA Astrophysics Data System (ADS)

Shevchenko, I. V.; Rogalev, A. N.; Osipov, S. K.; Bychkov, N. M.; Komarov, I. I.

2017-11-01

An emergence of modern innovative technologies requires delivering new and modernization existing design and production processes. It is especially relevant for designing the high-temperature turbines of gas turbine engines, development of which is characterized by a transition to higher parameters of working medium in order to improve their efficient performance. A design technique for gas turbine blades based on predictive verification of thermal and hydraulic models of their cooling systems by testing of a blade prototype fabricated using the selective laser melting technology was presented in this article. Technique was proven at the time of development of the first stage blade cooling system for the high-pressure turbine. An experimental procedure for verification of a thermal model of the blades with convective cooling systems based on the comparison of heat-flux density obtained from the numerical simulation data and results of tests in a liquid-metal thermostat was developed. The techniques makes it possible to obtain an experimentally tested blade version and to exclude its experimental adjustment after the start of mass production.

Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals.

PubMed

Susaki, Etsuo A; Ueda, Hiroki R

2016-01-21

Organism-level systems biology aims to identify, analyze, control and design cellular circuits in organisms. Many experimental and computational approaches have been developed over the years to allow us to conduct these studies. Some of the most powerful methods are based on using optical imaging in combination with fluorescent labeling, and for those one of the long-standing stumbling blocks has been tissue opacity. Recently, the solutions to this problem have started to emerge based on whole-body and whole-organ clearing techniques that employ innovative tissue-clearing chemistry. Here, we review these advancements and discuss how combining new clearing techniques with high-performing fluorescent proteins or small molecule tags, rapid volume imaging and efficient image informatics is resulting in comprehensive and quantitative organ-wide, single-cell resolution experimental data. These technologies are starting to yield information on connectivity and dynamics in cellular circuits at unprecedented resolution, and bring us closer to system-level understanding of physiology and diseases of complex mammalian systems. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Health care innovation from a territorial perspective: a call for a new approach].

PubMed

Costa, Laís Silveira; Gadelha, Carlos Augusto Grabois; Maldonado, José

2012-12-01

Innovation plays an increasingly important role in health care, partly because it is responsible for a significant share of national investment in research and development, and partly because of its industrial and service provision base, which provides a conduit to future technology. The relationship between health care and development is also strengthened as a result of the leading role of health care in generating innovation. Nevertheless, Brazil's health care production base is persistently weak, hindering both universal provision of health care services and international competitiveness. This article, based on the theoretical framework of Political Economy and innovation systems, has sought to identify variables in subnational contexts that influence the dynamic of innovation generation in health care. To this end, the theoretical approach used lies on the assumption that innovation is a contextualized social process and that the production base in healthcare will remain weak if new variables involved in the dynamic of innovation are not taken into account.

Enhancement of DRPE performance with a novel scheme based on new RAC: Principle, security analysis and FPGA implementation

NASA Astrophysics Data System (ADS)

Neji, N.; Jridi, M.; Alfalou, A.; Masmoudi, N.

2016-02-01

The double random phase encryption (DRPE) method is a well-known all-optical architecture which has many advantages especially in terms of encryption efficiency. However, the method presents some vulnerabilities against attacks and requires a large quantity of information to encode the complex output plane. In this paper, we present an innovative hybrid technique to enhance the performance of DRPE method in terms of compression and encryption. An optimized simultaneous compression and encryption method is applied simultaneously on the real and imaginary components of the DRPE output plane. The compression and encryption technique consists in using an innovative randomized arithmetic coder (RAC) that can well compress the DRPE output planes and at the same time enhance the encryption. The RAC is obtained by an appropriate selection of some conditions in the binary arithmetic coding (BAC) process and by using a pseudo-random number to encrypt the corresponding outputs. The proposed technique has the capabilities to process video content and to be standard compliant with modern video coding standards such as H264 and HEVC. Simulations demonstrate that the proposed crypto-compression system has presented the drawbacks of the DRPE method. The cryptographic properties of DRPE have been enhanced while a compression rate of one-sixth can be achieved. FPGA implementation results show the high performance of the proposed method in terms of maximum operating frequency, hardware occupation, and dynamic power consumption.

Overview of innovative remediation of emerging contaminants

NASA Astrophysics Data System (ADS)

Keller, A. A.; Adeleye, A. S.; Huang, Y.; Garner, K.

2015-12-01

The application of nanotechnology in drinking water treatment and pollution cleanup is promising, as demonstrated by a number of field-based (pilot and full scale) and bench scale studies. A number of reviews exist for these nanotechnology-based applications; but to better illustrate its importance and guide its development, a direct comparison between traditional treatment technologies and emerging approaches using nanotechnology is needed. In this review, the performances of traditional technologies and nanotechnology for water treatment and environmental remediation were compared with the goal of providing an up-to-date reference on the state of treatment techniques for researchers, industry, and policy makers. Pollutants were categorized into broad classes, and the most cost-effective techniques (traditional and nanotechnology-based) in each category reported in the literature were compared. Where information was available, cost and environmental implications of both technologies were also compared. Traditional treatment technologies were found to currently offer the most cost-effective choices for removal of several common pollutants from drinking water and polluted sites. Nano-based techniques may however become important in complicated remediation conditions and meeting increasingly stringent water quality standards, especially in removal of emerging pollutants and low levels of contaminants. We also discuss challenges facing environmental application of nanotechnology were also discussed and potential solutions.

Arthroscopy Authors Seek Innovative International Readers.

PubMed

Lubowitz, James H; Provencher, Matthew T; Rossi, Michael J; Brand, Jefferson C; Schmidt, Melissa B

2016-08-01

Arthroscopy and Arthroscopy Techniques attract authors as a result of our large, innovative, and global audience. In addition, the journals attract authors because of our robust and rapid review process, our wide indexing and search availability, and our openness to diverse article types including Technical Notes with video. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Disruptive technology for vector control: the Innovative Vector Control Consortium and the US Military join forces to explore transformative insecticide application technology for mosquito control programmes.

PubMed

Knapp, Jennifer; Macdonald, Michael; Malone, David; Hamon, Nicholas; Richardson, Jason H

2015-09-26

Malaria vector control technology has remained largely static for decades and there is a pressing need for innovative control tools and methodology to radically improve the quality and efficiency of current vector control practices. This report summarizes a workshop jointly organized by the Innovative Vector Control Consortium (IVCC) and the Armed Forces Pest Management Board (AFPMB) focused on public health pesticide application technology. Three main topics were discussed: the limitations with current tools and techniques used for indoor residual spraying (IRS), technology innovation to improve efficacy of IRS programmes, and truly disruptive application technology beyond IRS. The group identified several opportunities to improve application technology to include: insuring all IRS programmes are using constant flow valves and erosion resistant tips; introducing compression sprayer improvements that help minimize pesticide waste and human error; and moving beyond IRS by embracing the potential for new larval source management techniques and next generation technology such as unmanned "smart" spray systems. The meeting served to lay the foundation for broader collaboration between the IVCC and AFPMB and partners in industry, the World Health Organization, the Bill and Melinda Gates Foundation and others.

Innovation in diagnostic imaging services: assessing the potential for value-based reimbursement.

PubMed

Garrison, Louis P; Bresnahan, Brian W; Higashi, Mitchell K; Hollingworth, William; Jarvik, Jeffrey G

2011-09-01

Innovation in the field of diagnostic imaging is based primarily on the availability of new and improved equipment that opens the door for new clinical applications. Payments for these imaging procedures are subject to complex Medicare price control schemes, affecting incentives for appropriate use and innovation. Achieving a "dynamically efficient" health care system-one that elicits a socially optimal amount of innovation-requires that innovators be rewarded in relation to the value they add and can demonstrate with evidence. The authors examine how and whether value-based reimbursement for diagnostic imaging services might better reward innovation explicitly for expected improvements in health and economic outcomes. Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.

Innovation in Layer-by-Layer Assembly.

PubMed

Richardson, Joseph J; Cui, Jiwei; Björnmalm, Mattias; Braunger, Julia A; Ejima, Hirotaka; Caruso, Frank

2016-12-14

Methods for depositing thin films are important in generating functional materials for diverse applications in a wide variety of fields. Over the last half-century, the layer-by-layer assembly of nanoscale films has received intense and growing interest. This has been fueled by innovation in the available materials and assembly technologies, as well as the film-characterization techniques. In this Review, we explore, discuss, and detail innovation in layer-by-layer assembly in terms of past and present developments, and we highlight how these might guide future advances. A particular focus is on conventional and early developments that have only recently regained interest in the layer-by-layer assembly field. We then review unconventional assemblies and approaches that have been gaining popularity, which include inorganic/organic hybrid materials, cells and tissues, and the use of stereocomplexation, patterning, and dip-pen lithography, to name a few. A relatively recent development is the use of layer-by-layer assembly materials and techniques to assemble films in a single continuous step. We name this "quasi"-layer-by-layer assembly and discuss the impacts and innovations surrounding this approach. Finally, the application of characterization methods to monitor and evaluate layer-by-layer assembly is discussed, as innovation in this area is often overlooked but is essential for development of the field. While we intend for this Review to be easily accessible and act as a guide to researchers new to layer-by-layer assembly, we also believe it will provide insight to current researchers in the field and help guide future developments and innovation.

A novel approach to the dynamical complexity of the Earth's magnetosphere at geomagnetic storm time-scales based on recurrences

NASA Astrophysics Data System (ADS)

Donner, Reik; Balasis, Georgios; Stolbova, Veronika; Wiedermann, Marc; Georgiou, Marina; Kurths, Jürgen

2016-04-01

Magnetic storms are the most prominent global manifestations of out-of-equilibrium magnetospheric dynamics. Investigating the dynamical complexity exhibited by geomagnetic observables can provide valuable insights into relevant physical processes as well as temporal scales associated with this phenomenon. In this work, we introduce several innovative data analysis techniques enabling a quantitative analysis of the Dst index non-stationary behavior. Using recurrence quantification analysis (RQA) and recurrence network analysis (RNA), we obtain a variety of complexity measures serving as markers of quiet- and storm-time magnetospheric dynamics. We additionally apply these techniques to the main driver of Dst index variations, the V BSouth coupling function and interplanetary medium parameters Bz and Pdyn in order to discriminate internal processes from the magnetosphere's response directly induced by the external forcing by the solar wind. The derived recurrence-based measures allow us to improve the accuracy with which magnetospheric storms can be classified based on ground-based observations. The new methodology presented here could be of significant interest for the space weather research community working on time series analysis for magnetic storm forecasts.

Innovative techniques for evaluating behavioral nutrition interventions

USDA-ARS?s Scientific Manuscript database

Assessing outcomes and impact from behavioral nutrition interventions in the community has remained challenging for a variety of reasons. One main reason is the lack of methods available beyond traditional nutrition assessment tools and techniques. With current global obesity and related chronic dis...

PARTITIONING INTERWELL TRACER TEST FOR NAPL SOURCE CHARACTERIZATION: A GENERAL OVERVIEW

EPA Science Inventory

Innovative and nondestructive characterization techniques have been developed to locate and quantify nonaqueous phase liquids (NAPLs) in the vadose and saturated zones in the subsurface environment. One such technique is the partitioning interwell tracer test (PITT). The PITT i...

Innovative acoustic techniques for studying new materials and new developments in solid state physics

NASA Astrophysics Data System (ADS)

Maynard, Julian D.

1994-06-01

The goals of this project involve the use of innovative acoustic techniques to study new materials and new developments in solid state physics. Major accomplishments include (a) the preparation and publication of a number of papers and book chapters, (b) the measurement and new analysis of more samples of aluminum quasicrystal and its cubic approximant to eliminate the possibility of sample artifacts, (c) the use of resonant ultrasound to measure acoustic attenuation and determine the effects of heat treatment on ceramics, (d) the extension of our technique for measuring even lower (possibly the lowest) infrared optical absorption coefficient, and (e) the measurement of the effects of disorder on the propagation of a nonlinear pulse, and (f) the observation of statistical effects in measurements of individual bond breaking events in fracture.

A New Era of Minimally Invasive Surgery: Progress and Development of Major Technical Innovations in General Surgery Over the Last Decade.

PubMed

Siddaiah-Subramanya, Manjunath; Tiang, Kor Woi; Nyandowe, Masimba

2017-10-01

Minimally invasive surgery (MIS) continues to play an important role in general surgery as an alternative to traditional open surgery as well as traditional laparoscopic techniques. Since the 1980s, technological advancement and innovation have seen surgical techniques in MIS rapidly grow as it is viewed as more desirable. MIS, which includes natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopic surgery (SILS), is less invasive and has better cosmetic results. The technological growth and adoption of NOTES and SILS by clinicians in the last decade has however not been uniform. We look at the differences in new developments and advancement in the different techniques in the last 10 years. We also aim to explain these differences as well as the implications in general surgery for the future.

Dissolution enhancement of atorvastatin calcium by co-grinding technique.

PubMed

Prabhu, Priyanka; Patravale, Vandana

2016-08-01

Atorvastatin calcium (AC) is a BCS class II drug which shows poor bioavailability due to inadequate dissolution. Solid dispersions present a promising option to enhance the solubility of poorly soluble drugs. Co-grinding with hydrophilic excipients is an easy and economical technique to improve the solubility of poorly soluble drugs and is free from usage of organic solvents. The aim of the present study was to explore novel carrier VBP-1 (organosulphur compound) for formulating a solid dispersion by using a simple, commercially viable co-grinding technique to enhance the dissolution of AC and to develop an oral formulation of the same. Composition of the solid dispersion was optimized based on the release profile in pH 1.2 buffer. The optimized solid dispersion was further characterized for flow properties, DSC, FTIR spectroscopy, XRD, contact angle, SEM studies and release profile in phosphate buffer pH 6.8. The developed solid dispersion gave similar release profile as the innovator formulation (Lipitor® tablets) in both pH 1.2 buffer and phosphate buffer pH 6.8. The developed solid dispersion was formulated into hard gelatin capsules (size 3). The developed capsules were found to give similar release as the innovator formulation in both pH 1.2 buffer and phosphate buffer pH 6.8. The developed capsules were found to be stable for a period of 6 months. Anti-hyperlipidemic efficacy studies in rats showed higher reduction in cholesterol and triglyceride levels by the developed capsules in comparison to pure AC. In conclusion, novel carrier VBP-1 was successfully employed to enhance the dissolution of AC using co-grinding technique.

Enhancing Icing Training for Pilots Through Web-Based Multimedia

NASA Technical Reports Server (NTRS)

Fletcher, William; Nolan, Gary; Adanich, Emery; Bond, Thomas H.

2006-01-01

The Aircraft Icing Project of the NASA Aviation Safety Program has developed a number of in-flight icing education and training aids designed to increase pilot awareness about the hazards associated with various icing conditions. The challenges and advantages of transitioning these icing training materials to a Web-based delivery are discussed. Innovative Web-based delivery devices increased course availability to pilots and dispatchers while increasing course flexibility and utility. These courses are customizable for both self-directed and instructor-led learning. Part of our goal was to create training materials with enough flexibility to enable Web-based delivery and downloadable portability while maintaining a rich visual multimedia-based learning experience. Studies suggest that using visually based multimedia techniques increases the effectiveness of icing training materials. This paper describes these concepts, gives examples, and discusses the transitional challenges.

The Principal as a Key Actor in Promoting Teachers' Innovativeness--Analyzing the Innovativeness of Teaching Staff with Variance-Based Partial Least Square Modeling

ERIC Educational Resources Information Center

Buske, Ramona

2018-01-01

The study examines the correlation between collective innovativeness of the teaching staff and the principal's leadership style as well as additional school structure characteristics. The construct of collective innovativeness is examined as a precondition of successful school improvement processes driven by the teaching staff. Based on…

Wind energy prospecting: socio-economic value of a new wind resource assessment technique based on a NASA Earth science dataset

NASA Astrophysics Data System (ADS)

Vanvyve, E.; Magontier, P.; Vandenberghe, F. C.; Delle Monache, L.; Dickinson, K.

2012-12-01

Wind energy is amongst the fastest growing sources of renewable energy in the U.S. and could supply up to 20 % of the U.S power production by 2030. An accurate and reliable wind resource assessment for prospective wind farm sites is a challenging task, yet is crucial for evaluating the long-term profitability and feasibility of a potential development. We have developed an accurate and computationally efficient wind resource assessment technique for prospective wind farm sites, which incorporates innovative statistical techniques and the new NASA Earth science dataset MERRA. This technique produces a wind resource estimate that is more accurate than that obtained by the wind energy industry's standard technique, while providing a reliable quantification of its uncertainty. The focus now is on evaluating the socio-economic value of this new technique upon using the industry's standard technique. Would it yield lower financing costs? Could it result in lower electricity prices? Are there further down-the-line positive consequences, e.g. job creation, time saved, greenhouse gas decrease? Ultimately, we expect our results will inform efforts to refine and disseminate the new technique to support the development of the U.S. renewable energy infrastructure. In order to address the above questions, we are carrying out a cost-benefit analysis based on the net present worth of the technique. We will describe this approach, including the cash-flow process of wind farm financing, how the wind resource assessment factors in, and will present current results for various hypothetical candidate wind farm sites.

Problem Solving Process Research of Everyone Involved in Innovation Based on CAI Technology

NASA Astrophysics Data System (ADS)

Chen, Tao; Shao, Yunfei; Tang, Xiaowo

It is very important that non-technical department personnel especially bottom line employee serve as innovators under the requirements of everyone involved in innovation. According the view of this paper, it is feasible and necessary to build everyone involved in innovation problem solving process under Total Innovation Management (TIM) based on the Theory of Inventive Problem Solving (TRIZ). The tools under the CAI technology: How TO mode and science effects database could be very useful for all employee especially non-technical department and bottom line for innovation. The problem solving process put forward in the paper focus on non-technical department personnel especially bottom line employee for innovation.

Sustaining Knowledge Building as a Principle-Based Innovation at an Elementary School

ERIC Educational Resources Information Center

Zhang, Jianwei; Hong, Huang-Yao; Scardamalia, Marlene; Teo, Chew Lee; Morley, Elizabeth A.

2011-01-01

This study explores Knowledge Building as a principle-based innovation at an elementary school and makes a case for a principle- versus procedure-based approach to educational innovation, supported by new knowledge media. Thirty-nine Knowledge Building initiatives, each focused on a curriculum theme and facilitated by nine teachers over eight…

Innovating Method of Existing Mechanical Product Based on TRIZ Theory

NASA Astrophysics Data System (ADS)

Zhao, Cunyou; Shi, Dongyan; Wu, Han

Main way of product development is adaptive design and variant design based on existing product. In this paper, conceptual design frame and its flow model of innovating products is put forward through combining the methods of conceptual design and TRIZ theory. Process system model of innovating design that includes requirement analysis, total function analysis and decomposing, engineering problem analysis, finding solution of engineering problem and primarily design is constructed and this establishes the base for innovating design of existing product.

A novel technique for performing a tongue-lip adhesion-the tongue suspension technique.

PubMed

Mann, Robert J; Neaman, Keith C; Hill, Brian; Bajnrauh, Robert; Martin, Matthew D

2012-01-01

The tongue-lip adhesion has undergone several modifications in an attempt to reduce surgical complications and failure rates. Current techniques rely on the use of a button at the tongue base for suspension, which raises concerns about possible aspiration and interference with oral motor function and bottle-feeding. A new technique for tongue-lip adhesion is proposed that adds a tongue suspension to the standard surgical adhesion. A total of 22 patients with Pierre Robin sequence who received a tongue-lip adhesion via a tongue suspension technique were reviewed. The surgical technique differs from the standard surgical approach by the use of a suture weave across the base of the tongue instead of a standard button to suspend the tongue anteriorly. Average age at the time of tongue-lip adhesion was 13.9 days, with a mean operative time of 88.8 minutes. A marked improvement in postoperative oxygenation was seen in the majority of patients. One dehiscence occurred secondary to a traumatic postoperative extubation, eventually requiring a tracheostomy for subglottic stenosis. A technical innovation for performing a tongue-lip adhesion using a tongue suspension in conjunction with a standard transverse adhesion of the lip is described. The advantage of the tongue-lip adhesion with suspension includes immediate postoperative extubation, as well as removal of concerns regarding button aspiration and possible interference in early developmental oral motor function and bottle-feeding. This technique is reproducible, expanding the craniofacial surgeon's armamentarium for the management of difficult airways in Pierre Robin sequence.

A whole-process progressive training mode to foster optoelectronic students' innovative practical ability

NASA Astrophysics Data System (ADS)

Zhong, Hairong; Xu, Wei; Hu, Haojun; Duan, Chengfang

2017-08-01

This article analyzes the features of fostering optoelectronic students' innovative practical ability based on the knowledge structure of optoelectronic disciplines, which not only reveals the common law of cultivating students' innovative practical ability, but also considers the characteristics of the major: (1) The basic theory is difficult, and the close combination of science and technology is obvious; (2)With the integration of optics, mechanics, electronics and computer, the system technology is comprehensive; (3) It has both leading-edge theory and practical applications, so the benefit of cultivating optoelectronic students is high ; (4) The equipment is precise and the practice is costly. Considering the concept and structural characteristics of innovative and practical ability, and adhering to the idea of running practice through the whole process, we put forward the construction of three-dimensional innovation and practice platform which consists of "Synthetically Teaching Laboratory + Innovation Practice Base + Scientific Research Laboratory + Major Practice Base + Joint Teaching and Training Base", and meanwhile build a whole-process progressive training mode to foster optoelectronic students' innovative practical ability, following the process of "basic experimental skills training - professional experimental skills training - system design - innovative practice - scientific research project training - expanded training - graduation project": (1) To create an in - class practical ability cultivation environment that has distinctive characteristics of the major, with the teaching laboratory as the basic platform; (2) To create an extra-curricular innovation practice activities cultivation environment that is closely linked to the practical application, with the innovation practice base as a platform for improvement; (3) To create an innovation practice training cultivation environment that leads the development of cutting-edge, with the scientific research laboratory as a platform to explore; (4) To create an out-campus expanded training environment of optoelectronic major practice and optoelectronic system teaching and training, with the major practice base as an expansion of the platform; (5) To break students' "pre-job training barriers" between school and work, with graduation design as the comprehensive training and testing link.

Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017)

PubMed Central

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant

2017-01-01

Objective Digital innovations with internet/mobile phones offer a potential cost-saving solution for overburdened health systems with high service delivery costs to improve efficiency of HIV/STI (sexually transmitted infections) control initiatives. However, their overall evidence has not yet been appraised. We evaluated the feasibility and impact of all digital innovations for all HIV/STIs. Design Systematic review. Setting/participants All settings/all participants. Intervention We classified digital innovations into (1) mobile health-based (mHealth: SMS (short message service)/phone calls), (2) internet-based mobile and/or electronic health (mHealth/eHealth: social media, avatar-guided computer programs, websites, mobile applications, streamed soap opera videos) and (3) combined innovations (included both SMS/phone calls and internet-based mHealth/eHealth). Primary and secondary outcome measures Feasibility, acceptability, impact. Methods We searched databases MEDLINE via PubMed, Embase, Cochrane CENTRAL and Web of Science, abstracted data, explored heterogeneity, performed a random effects subgroup analysis. Results We reviewed 99 studies, 63 (64%) were from America/Europe, 36 (36%) from Africa/Asia; 79% (79/99) were clinical trials; 84% (83/99) evaluated impact. Of innovations, mHealth based: 70% (69/99); internet based: 21% (21/99); combined: 9% (9/99). All digital innovations were highly accepted (26/31; 84%), and feasible (20/31; 65%). Regarding impacted measures, mHealth-based innovations (SMS) significantly improved antiretroviral therapy (ART) adherence (pooled OR=2.15(95%CI: 1.18 to 3.91)) and clinic attendance rates (pooled OR=1.76(95%CI: 1.28, 2.42)); internet-based innovations improved clinic attendance (6/6), ART adherence (4/4), self-care (1/1), while reducing risk (5/5); combined innovations increased clinic attendance, ART adherence, partner notifications and self-care. Confounding (68%) and selection bias (66%) were observed in observational studies and attrition bias in 31% of clinical trials. Conclusion Digital innovations were acceptable, feasible and generated impact. A trend towards the use of internet-based and combined (internet and mobile) innovations was noted. Large scale-up studies of high quality, with new integrated impact metrics, and cost-effectiveness are needed. Findings will appeal to all stakeholders in the HIV/STI global initiatives space. PMID:29101138

Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017).

PubMed

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant

2017-11-03

Digital innovations with internet/mobile phones offer a potential cost-saving solution for overburdened health systems with high service delivery costs to improve efficiency of HIV/STI (sexually transmitted infections) control initiatives. However, their overall evidence has not yet been appraised. We evaluated the feasibility and impact of all digital innovations for all HIV/STIs. Systematic review. All settings/all participants. We classified digital innovations into (1) mobile health-based (mHealth: SMS (short message service)/phone calls), (2) internet-based mobile and/or electronic health (mHealth/eHealth: social media, avatar-guided computer programs, websites, mobile applications, streamed soap opera videos) and (3) combined innovations (included both SMS/phone calls and internet-based mHealth/eHealth). Feasibility, acceptability, impact. We searched databases MEDLINE via PubMed, Embase, Cochrane CENTRAL and Web of Science, abstracted data, explored heterogeneity, performed a random effects subgroup analysis. We reviewed 99 studies, 63 (64%) were from America/Europe, 36 (36%) from Africa/Asia; 79% (79/99) were clinical trials; 84% (83/99) evaluated impact. Of innovations, mHealth based: 70% (69/99); internet based: 21% (21/99); combined: 9% (9/99).All digital innovations were highly accepted (26/31; 84%), and feasible (20/31; 65%). Regarding impacted measures, mHealth-based innovations (SMS) significantly improved antiretroviral therapy (ART) adherence (pooled OR=2.15(95%CI: 1.18 to 3.91)) and clinic attendance rates (pooled OR=1.76(95%CI: 1.28, 2.42)); internet-based innovations improved clinic attendance (6/6), ART adherence (4/4), self-care (1/1), while reducing risk (5/5); combined innovations increased clinic attendance, ART adherence, partner notifications and self-care. Confounding (68%) and selection bias (66%) were observed in observational studies and attrition bias in 31% of clinical trials. Digital innovations were acceptable, feasible and generated impact. A trend towards the use of internet-based and combined (internet and mobile) innovations was noted. Large scale-up studies of high quality, with new integrated impact metrics, and cost-effectiveness are needed. Findings will appeal to all stakeholders in the HIV/STI global initiatives space. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Evolutions in fragment-based drug design: the deconstruction–reconstruction approach

PubMed Central

Chen, Haijun; Zhou, Xiaobin; Wang, Ailan; Zheng, Yunquan; Gao, Yu; Zhou, Jia

2014-01-01

Recent advances in the understanding of molecular recognition and protein–ligand interactions have facilitated rapid development of potent and selective ligands for therapeutically relevant targets. Over the past two decades, a variety of useful approaches and emerging techniques have been developed to promote the identification and optimization of leads that have high potential for generating new therapeutic agents. Intriguingly, the innovation of a fragment-based drug design (FBDD) approach has enabled rapid and efficient progress in drug discovery. In this critical review, we focus on the construction of fragment libraries and the advantages and disadvantages of various fragment-based screening (FBS) for constructing such libraries. We also highlight the deconstruction–reconstruction strategy by utilizing privileged fragments of reported ligands. PMID:25263697

Measuring the style of innovative thinking among engineering students

NASA Astrophysics Data System (ADS)

Passig, David; Cohen, Lizi

2014-01-01

Background: Many tools have been developed to measure the ability of workers to innovate. However, all of them are based on self-reporting questionnaires, which raises questions about their validity Purpose: The aim was to develop and validate a tool, called Ideas Generation Implementation (IGI), to objectively measure the style and potential of engineering students in generating innovative technological ideas. The cognitive framework of IGI is based on the Architectural Innovation Model (AIM). Tool description: The IGI tool was designed to measure the level of innovation in generating technological ideas and their potential to be implemented. These variables rely on the definition of innovation as 'creativity, implemented in a high degree of success'. The levels of innovative thinking are based on the AIM and consist of four levels: incremental innovation, modular innovation, architectural innovation and radical innovation. Sample: Sixty experts in technological innovation developed the tool. We checked its face validity and calculated its reliability in a pilot study (kappa = 0.73). Then, 145 undergraduate students were sampled at random from the seven Israeli universities offering engineering programs and asked to complete the questionnaire. Design and methods: We examined the construct validity of the tool by conducting a variance analysis and measuring the correlations between the innovator's style of each student, as suggested by the AIM, and the three subscale factors of creative styles (efficient, conformist and original), as suggested by the Kirton Adaptors and Innovators (KAI) questionnaire. Results: Students with a radical innovator's style inclined more than those with an incremental innovator's style towards the three creative cognitive styles. Students with an architectural innovator's style inclined moderately, but not significantly, towards the three creative styles. Conclusions: The IGI tool objectively measures innovative thinking among students, thus allowing screening of potential employees at an early stage, during their undergraduate studies. The tool was found to be reliable and valid in measuring the style and potential of technological innovation among engineering students.

Advances in Electrically Driven Thermal Management

NASA Technical Reports Server (NTRS)

Didion, Jeffrey R.

2017-01-01

Electrically Driven Thermal Management is a vibrant technology development initiative incorporating ISS based technology demonstrations, development of innovative fluid management techniques and fundamental research efforts. The program emphasizes high temperature high heat flux thermal management required for future generations of RF electronics and power electronic devices. This presentation reviews i.) preliminary results from the Electrohydrodynamic (EHD) Long Term Flight Demonstration launched on STP-H5 payload in February 2017 ii.) advances in liquid phase flow distribution control iii.) development of the Electrically Driven Liquid Film Boiling Experiment under the NASA Microgravity Fluid Physics Program.

[Transanal total mesorectal excision for rectal cancer - just a fashion trend?].

PubMed

Kala, Z; Skrovina, M; Procházka, V; Grolich, T; Klos, K

2014-12-01

Transanal total mesorectal excision performed using equipment for transanal minimally invasive surgery is an innovative surgical technique introduced to facilitate this procedure and to reach better oncosurgical outcomes in patients with low rectal cancer. This article presents a brief summary of guidelines for treatment of patients with low rectal carcinoma. Up-to-date information about the principles of this new method, its modifications and contemporary indications is presented. Based on their own experience and literature resources, the authors inform about the advantages, limitations and unresolved issues of minimally invasive transanal mesorectal excision.

ERM Ideas and Innovations: Digital Repository Management as ERM

ERIC Educational Resources Information Center

Pinkas, María M.; Lin, Na

2014-01-01

This article describes the application of electronic resources management (ERM) to digital repository management at the Health Sciences and Human Services Library at the University of Maryland, Baltimore. The authors discuss electronic resources management techniques, through the application of "Techniques for Electronic Management,"…

A review of second law techniques applicable to basic thermal science research

NASA Astrophysics Data System (ADS)

Drost, M. Kevin; Zamorski, Joseph R.

1988-11-01

This paper reports the results of a review of second law analysis techniques which can contribute to basic research in the thermal sciences. The review demonstrated that second law analysis has a role in basic thermal science research. Unlike traditional techniques, second law analysis accurately identifies the sources and location of thermodynamic losses. This allows the development of innovative solutions to thermal science problems by directing research to the key technical issues. Two classes of second law techniques were identified as being particularly useful. First, system and component investigations can provide information of the source and nature of irreversibilities on a macroscopic scale. This information will help to identify new research topics and will support the evaluation of current research efforts. Second, the differential approach can provide information on the causes and spatial and temporal distribution of local irreversibilities. This information enhances the understanding of fluid mechanics, thermodynamics, and heat and mass transfer, and may suggest innovative methods for reducing irreversibilities.

A comparison of essential oils obtained from lavandin via different extraction processes: Ultrasound, microwave, turbohydrodistillation, steam and hydrodistillation.

PubMed

Périno-Issartier, Sandrine; Ginies, Christian; Cravotto, Giancarlo; Chemat, Farid

2013-08-30

A total of eight extraction techniques ranging from conventional methods (hydrodistillation (HD), steam distillation (SD), turbohydrodistillation (THD)), through innovative techniques (ultrasound assisted extraction (US-SD) and finishing with microwave assisted extraction techniques such as In situ microwave-generated hydrodistillation (ISMH), microwave steam distillation (MSD), microwave hydrodiffusion and gravity (MHG), and microwave steam diffusion (MSDf)) were used to extract essential oil from lavandin flowers and their results were compared. Extraction time, yield, essential oil composition and sensorial analysis were considered as the principal terms of comparison. The essential oils extracted using the more innovative processes were quantitatively (yield) and qualitatively (aromatic profile) similar to those obtained from the conventional techniques. The method which gave the best results was the microwave hydrodiffusion and gravity (MHG) method which gave reduced extraction time (30min against 220min for SD) and gave no differences in essential oil yield and sensorial perception. Copyright © 2013 Elsevier B.V. All rights reserved.

[Review on enterprises'eco-innovation].

PubMed

Liao, Zhong Ju; Huang, Chao

2017-12-01

Eco-innovation is an important way to realize sustainable development. It has the dual positive externality of "knowledge spillover" and "environmental spillover", which has attracted much attention from theory and practice. In order to systematically grasp the current situation of eco-innovation, this study collected the relevant foreign literatures on eco-innovation in the past ten years, and made a systematic review of the definition, characteristics and dimensions of eco-innovation. Focusing on the theory of institutional theory, stakeholder theory and resource-based view, this paper explored the antecedents of eco-innovation. Then, this paper also demonstrated the positive and negative effects of eco-innovation on corporate financial performance, and the meditating and moderating mechanisms between eco-innovation and financial performance. Finally, based on the limitations of existing research, the future research direction was put forward.

Predicting Innovation Acceptance by Simulation in Virtual Environments (Theoretical Foundations)

NASA Astrophysics Data System (ADS)

León, Noel; Duran, Roberto; Aguayo, Humberto; Flores, Myrna

This paper extends the current development of a methodology for Computer Aided Innovation. It begins with a presentation of concepts related to the perceived capabilities of virtual environments in the Innovation Cycle. The main premise establishes that it is possible to predict the acceptance of a new product in a specific market, by releasing an early prototype in a virtual scenario to quantify its general reception and to receive early feedback from potential customers. The paper continues to focus this research on a synergistic extension of techniques that have their origins in optimization and innovation disciplines. TRIZ (Theory of Inventive Problem Solving), extends the generation of variants with Evolutionary Algorithms (EA) and finally to present the designer and the intended customer, creative and innovative alternatives. All of this developed on a virtual software interface (Virtual World). The work continues with a general description of the project as a step forward to improve the overall strategy.

An Improved Map-Matching Technique Based on the Fréchet Distance Approach for Pedestrian Navigation Services

PubMed Central

Bang, Yoonsik; Kim, Jiyoung; Yu, Kiyun

2016-01-01

Wearable and smartphone technology innovations have propelled the growth of Pedestrian Navigation Services (PNS). PNS need a map-matching process to project a user’s locations onto maps. Many map-matching techniques have been developed for vehicle navigation services. These techniques are inappropriate for PNS because pedestrians move, stop, and turn in different ways compared to vehicles. In addition, the base map data for pedestrians are more complicated than for vehicles. This article proposes a new map-matching method for locating Global Positioning System (GPS) trajectories of pedestrians onto road network datasets. The theory underlying this approach is based on the Fréchet distance, one of the measures of geometric similarity between two curves. The Fréchet distance approach can provide reasonable matching results because two linear trajectories are parameterized with the time variable. Then we improved the method to be adaptive to the positional error of the GPS signal. We used an adaptation coefficient to adjust the search range for every input signal, based on the assumption of auto-correlation between consecutive GPS points. To reduce errors in matching, the reliability index was evaluated in real time for each match. To test the proposed map-matching method, we applied it to GPS trajectories of pedestrians and the road network data. We then assessed the performance by comparing the results with reference datasets. Our proposed method performed better with test data when compared to a conventional map-matching technique for vehicles. PMID:27782091

Endoscopic hip osteotomies: less invasive approaches to peri-acetabular, proximal femoral and pubic symphyseal procedures

PubMed Central

Matsuda, Dean K.; Matsuda, Nicole A.

2015-01-01

Beyond the recent expansion of extra-articular hip arthroscopy into the peri-trochanteric and subgluteal space, this instructional course lecture introduces three innovative procedures: endoscopy-assisted periacetabular osteotomy, closed derotational proximal femoral osteotomy and endoscopic pubic symphysectomy. Supportive rationale, evolving indications, key surgical techniques and emerging outcomes are presented for these innovative less invasive procedures. PMID:27011827

Applied Computational Electromagnetics Society Journal and Newletter, Volume 14 No. 1

DTIC Science & Technology

1999-03-01

code validation, performance analysis, and input/output standardization; code or technique optimization and error minimization; innovations in...SOUTH AFRICA Alamo, CA, 94507-0516 USA Washington, DC 20330 USA MANAGING EDITOR Kueichien C. Hill Krishna Naishadham Richard W. Adler Wright Laboratory...INSTITUTIONAL MEMBERS ALLGON DERA Nasvagen 17 Common Road, Funtington INNOVATIVE DYNAMICS Akersberga, SWEDEN S-18425 Chichester, P018 9PD UK 2560 N. Triphammer

Therapeutic upper gastrointestinal tract endoscopy in Paediatric Gastroenterology

PubMed Central

Rahman, Imdadur; Patel, Praful; Boger, Philip; Rasheed, Shahnawaz; Thomson, Mike; Afzal, Nadeem Ahmad

2015-01-01

Since the first report of use of endoscopy in children in the 1970s, there has seen an exponential growth in published experience and innovation in the field. In this review article we focus on modern age therapeutic endoscopy practice, explaining use of traditional as well as new and innovative techniques, for diagnosis and treatment of diseases in the paediatric upper gastrointestinal tract. PMID:25789087

Robotic kidney transplantation with regional hypothermia: evolution of a novel procedure utilizing the IDEAL guidelines (IDEAL phase 0 and 1).

PubMed

Menon, Mani; Abaza, Ronney; Sood, Akshay; Ahlawat, Rajesh; Ghani, Khurshid R; Jeong, Wooju; Kher, Vijay; Kumar, Ramesh K; Bhandari, Mahendra

2014-05-01

Surgical innovation is essential for progress of surgical science, but its implementation comes with potential harms during the learning phase. The Balliol Collaboration has recommended a set of guidelines (Innovation, Development, Exploration, Assessment, Long-term study [IDEAL]) that permit innovation while minimizing complications. To utilize the IDEAL model of surgical innovation in the development of a novel surgical technique, robotic kidney transplantation (RKT) with regional hypothermia, and describe the process of discovery and development. Phase 0 (simulation) studies included the establishment of techniques for pelvic cooling, graft placement in a robotic prostatectomy model, and simulation of the RKT procedure in a cadaveric model. Phase 1 (innovation) studies began in January 2013 and involved treatment of a highly selective small group of patients (n=7), using the principles utilized in the phase 0 studies, at a tertiary referral center. IDEAL model implementation in the development of RKT with regional hypothermia. For phase 0 studies, the outcomes evaluated included pelvic and body temperature measurements, and technical feasibility assessment. The primary outcome during phase 1 was post-transplant graft function. Other outcomes measured were operative and ischemic times, perioperative complications, and intracorporeal graft surface temperature. Phase 0 (simulation phase): Pelvic cooling to 15-20(o)C was achieved reproducibly. Using the surgical approach developed for robotic radical prostatectomy, vascular and ureterovesical anastomoses could be done without redocking the robot. Phase 1 (innovation phase): All patients underwent live-donor RKT in the lithotomy position. All grafts functioned immediately. Mean console, anastomotic, and warm ischemia times were 154 min, 29 min, and 2 min, respectively. One patient was re-explored on postoperative day 1. Adherence to the IDEAL guidelines put forth by the Balliol Collaboration provided a practical framework for the establishment of a novel surgical procedure, RKT with regional hypothermia, without exposing the initial patients to unacceptable risk. The IDEAL model allows safe introduction of new surgical techniques without compromising patient outcomes. Copyright © 2013 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Allogenic banking of dental pulp stem cells for innovative therapeutics.

PubMed

Collart-Dutilleul, Pierre-Yves; Chaubron, Franck; De Vos, John; Cuisinier, Frédéric J

2015-08-26

Medical research in regenerative medicine and cell-based therapy has brought encouraging perspectives for the use of stem cells in clinical trials. Multiple types of stem cells, from progenitors to pluripotent stem cells, have been investigated. Among these, dental pulp stem cells (DPSCs) are mesenchymal multipotent cells coming from the dental pulp, which is the soft tissue within teeth. They represent an interesting adult stem cell source because they are recovered in large amount in dental pulps with non-invasive techniques compared to other adult stem cell sources. DPSCs can be obtained from discarded teeth, especially wisdom teeth extracted for orthodontic reasons. To shift from promising preclinical results to therapeutic applications to human, DPSCs must be prepared in clinical grade lots and transformed into advanced therapy medicinal products (ATMP). As the production of patient-specific stem cells is costly and time-consuming, allogenic biobanking of clinical grade human leukocyte antigen (HLA)-typed DPSC lines provides efficient innovative therapeutic products. DPSC biobanks represent industrial and therapeutic innovations by using discarded biological tissues (dental pulps) as a source of mesenchymal stem cells to produce and store, in good manufacturing practice (GMP) conditions, DPSC therapeutic batches. In this review, we discuss about the challenges to transfer biological samples from a donor to HLA-typed DPSC therapeutic lots, following regulations, GMP guidelines and ethical principles. We also present some clinical applications, for which there is no efficient therapeutics so far, but that DPSCs-based ATMP could potentially treat.

Allogenic banking of dental pulp stem cells for innovative therapeutics

PubMed Central

Collart-Dutilleul, Pierre-Yves; Chaubron, Franck; De Vos, John; Cuisinier, Frédéric J

2015-01-01

Medical research in regenerative medicine and cell-based therapy has brought encouraging perspectives for the use of stem cells in clinical trials. Multiple types of stem cells, from progenitors to pluripotent stem cells, have been investigated. Among these, dental pulp stem cells (DPSCs) are mesenchymal multipotent cells coming from the dental pulp, which is the soft tissue within teeth. They represent an interesting adult stem cell source because they are recovered in large amount in dental pulps with non-invasive techniques compared to other adult stem cell sources. DPSCs can be obtained from discarded teeth, especially wisdom teeth extracted for orthodontic reasons. To shift from promising preclinical results to therapeutic applications to human, DPSCs must be prepared in clinical grade lots and transformed into advanced therapy medicinal products (ATMP). As the production of patient-specific stem cells is costly and time-consuming, allogenic biobanking of clinical grade human leukocyte antigen (HLA)-typed DPSC lines provides efficient innovative therapeutic products. DPSC biobanks represent industrial and therapeutic innovations by using discarded biological tissues (dental pulps) as a source of mesenchymal stem cells to produce and store, in good manufacturing practice (GMP) conditions, DPSC therapeutic batches. In this review, we discuss about the challenges to transfer biological samples from a donor to HLA-typed DPSC therapeutic lots, following regulations, GMP guidelines and ethical principles. We also present some clinical applications, for which there is no efficient therapeutics so far, but that DPSCs-based ATMP could potentially treat. PMID:26328017

Characterization of Particles Created By Laser-Driven Hydrothermal Processing

DTIC Science & Technology

2016-06-01

created by laser-driven hydrothermal processing, an innovative technique used for the ablation of submerged materials. Two naturally occurring...processing, characterization, obsidian, tektite, natural glass 15. NUMBER OF PAGES 89 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT...technique used for the ablation of submerged materials. Two naturally occurring materials, obsidian and tektite, were used as targets for this technique

Using Innovative Technologies for Manufacturing and Evaluating Rocket Engine Hardware

NASA Technical Reports Server (NTRS)

Betts, Erin M.; Hardin, Andy

2011-01-01

Many of the manufacturing and evaluation techniques that are currently used for rocket engine component production are traditional methods that have been proven through years of experience and historical precedence. As we enter into a new space age where new launch vehicles are being designed and propulsion systems are being improved upon, it is sometimes necessary to adopt new and innovative techniques for manufacturing and evaluating hardware. With a heavy emphasis on cost reduction and improvements in manufacturing time, manufacturing techniques such as Direct Metal Laser Sintering (DMLS) and white light scanning are being adopted and evaluated for their use on J-2X, with hopes of employing both technologies on a wide variety of future projects. DMLS has the potential to significantly reduce the processing time and cost of engine hardware, while achieving desirable material properties by using a layered powdered metal manufacturing process in order to produce complex part geometries. The white light technique is a non-invasive method that can be used to inspect for geometric feature alignment. Both the DMLS manufacturing method and the white light scanning technique have proven to be viable options for manufacturing and evaluating rocket engine hardware, and further development and use of these techniques is recommended.

What is the impact of innovation on output in healthcare with a special focus on treatment innovations in radiotherapy? A literature review.

PubMed

Jacobs, Maria; Boersma, Liesbeth; Dekker, Andre; Swart, Rachelle; Lambin, Philippe; de Ruysscher, Dirk; Verhaegen, Frank; Stultiens, Joost; Ramaekers, Bram; van Merode, Frits

2017-11-01

To analyse how often innovations in healthcare are evaluated regarding output, especially in radiotherapy. Output was defined as either survival, toxicity, safety, service, efficiency or cost-effectiveness. A systematic literature review was conducted, using three search strategies: (1) innovations in general healthcare; (2) radiotherapy-specific innovations, i.e. organizational innovations and general implementation of innovations; (3) innovations per tumour group/radiotherapy technique. Scientific levels were classified according to the system used in European Society for Medical Oncology guidelines. Finally, we calculated the percentage of implemented innovations in Dutch radiotherapy centres for which we found evidence regarding output in the literature review. Only 94/1072 unique articles matched the inclusion criteria. Significant results on patient outcome, service or safety were reported in 65% of papers, which rose to 76% if confined to radiotherapy reviews. A significant technological improvement was identified in 26%, cost-effectiveness in 10% and costs/efficiency in 36% of the papers. The scientific level of organizational innovations was lower than that of clinical papers. Dutch radiotherapy treatment innovations were adequately evaluated on outcome data before implementation in clinical routine in a minimum of 64-92% of cases. Only few studies report on output when considering innovations in general, but radiotherapy reviews give a reasonably good insight into innovation output effects, with a higher level of evidence. In Dutch radiotherapy centres only small improvements are possible regarding evaluation of treatment innovations before implementation. Advances in knowledge: This study is the first of its kind measuring how innovations are evaluated in scientific literature, before implementation in clinical practice.

Treatment of gummy smile: Gingival recontouring with the containment of the elevator muscle of the upper lip and wing of nose. A surgery innovation technique.

PubMed

Storrer, Carmen Lucia Mueller; Valverde, Fabiane Kristine Bochenek; Santos, Felipe Rychuv; Deliberador, Tatiana Miranda

2014-09-01

The containment of the elevator muscle of the upper lip and wing of nose was used for the treatment of patients with gummy smile. This technique had corrected esthetic alterations of smile, reducing the upper lip elevation, which results in a smaller gingival display. An upper lip lengthening as well as a reduction in the upper lip shortening when the patient smiled could be observed. The high smile line was corrected without compromising the labial harmony. This study presents an innovative and effective therapeutic option to obtain a natural and harmonious smile. The patient expressed a high degree of satisfaction.

Early use of pressure flaking on lithic artifacts at Blombos Cave, South Africa.

PubMed

Mourre, Vincent; Villa, Paola; Henshilwood, Christopher S

2010-10-29

Pressure flaking has been considered to be an Upper Paleolithic innovation dating to ~20,000 years ago (20 ka). Replication experiments show that pressure flaking best explains the morphology of lithic artifacts recovered from the ~75-ka Middle Stone Age levels at Blombos Cave, South Africa. The technique was used during the final shaping of Still Bay bifacial points made on heat-treated silcrete. Application of this innovative technique allowed for a high degree of control during the detachment of individual flakes, resulting in thinner, narrower, and sharper tips on bifacial points. This technology may have been first invented and used sporadically in Africa before its later widespread adoption.

JUST in time health emergency interventions: an innovative approach to training the citizen for emergency situations using virtual reality techniques and advanced IT tools (the VR Tool).

PubMed

Manganas, A; Tsiknakis, M; Leisch, E; Ponder, M; Molet, T; Herbelin, B; Magnetat-Thalmann, N; Thalmann, D; Fato, M; Schenone, A

2004-01-01

This paper reports the results of the second of the two systems developed by JUST, a collaborative project supported by the European Union under the Information Society Technologies (IST) Programme. The most innovative content of the project has been the design and development of a complementary training course for non-professional health emergency operators, which supports the traditional learning phase, and which purports to improve the retention capability of the trainees. This was achieved with the use of advanced information technology techniques, which provide adequate support and can help to overcome the present weaknesses of the existing training mechanisms.

The Japan Society for Innovative Cuisine: Exploring New Visions of Japanese Cuisine.

PubMed

Yamazaki, Hanae; Fushiki, Tohru

2015-01-01

Kyoto cuisine has a long history and its traditions have been practiced for hundreds of years. In Kyoto, a group of scientists and renowned chefs strives to better understand traditional Kyoto cuisine in order to foster culinary innovation within traditional Kyoto cuisine. We launched a research project in April 2009 using a specially equipped "laboratory-kitchen" located in Kyoto University. Chefs chose a variety of topics related to basic concepts and techniques for cooking. We conducted culinary experimentation, thorough analysis, and diligent discussion on each topic for approximately 6 mo. In the symposium, chefs will present the results of their experiments, discussing their techniques and bringing samples of final products.

Imprisoned Resources--Innovative Techniques in Educating Prison Inmates.

ERIC Educational Resources Information Center

Wood, Larry F.; Jenkins, William O.

The effectiveness of employing educationally advanced inmates as one-to-one basic education tutors for inmate students was evaluated. In conjunction with this evaluation, an experimental study of the most efficient material presentation and testing techniques using this manpower resource was conducted. Three different modes of presenting…

Innovative Reactive and Proactive Graduate Student Recruiting Techniques.

ERIC Educational Resources Information Center

Laird, Hugh E., II

1989-01-01

The evolution of the recruiting techniques used by the University of Arizona's pharmacology and toxicology graduate program are described, considerations in the development of recruitment efforts are discussed, and issues for the profession to examine in developing a long-term strategy for recruiting students are outlined. (MSE)

Northern Everglades, Florida, satellite image map

USGS Publications Warehouse

Thomas, Jean-Claude; Jones, John W.

2002-01-01

These satellite image maps are one product of the USGS Land Characteristics from Remote Sensing project, funded through the USGS Place-Based Studies Program with support from the Everglades National Park. The objective of this project is to develop and apply innovative remote sensing and geographic information system techniques to map the distribution of vegetation, vegetation characteristics, and related hydrologic variables through space and over time. The mapping and description of vegetation characteristics and their variations are necessary to accurately simulate surface hydrology and other surface processes in South Florida and to monitor land surface changes. As part of this research, data from many airborne and satellite imaging systems have been georeferenced and processed to facilitate data fusion and analysis. These image maps were created using image fusion techniques developed as part of this project.

Successful Innovations in Educational Leadership Preparation

ERIC Educational Resources Information Center

Gordon, Stephen P.; Oliver, John; Solis, Rachel

2016-01-01

The purpose of this study was to identify and describe successful innovations in educational leadership preparation programs. Professors of educational leadership from across the nation nominated innovations of 12 programs. Based on review of descriptions of the innovations provided by nominees, further documentation on the innovations was…

A Human Reliability Based Usability Evaluation Method for Safety-Critical Software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillippe Palanque; Regina Bernhaupt; Ronald Boring

2006-04-01

Recent years have seen an increasing use of sophisticated interaction techniques including in the field of safety critical interactive software [8]. The use of such techniques has been required in order to increase the bandwidth between the users and systems and thus to help them deal efficiently with increasingly complex systems. These techniques come from research and innovation done in the field of humancomputer interaction (HCI). A significant effort is currently being undertaken by the HCI community in order to apply and extend current usability evaluation techniques to these new kinds of interaction techniques. However, very little has been donemore » to improve the reliability of software offering these kinds of interaction techniques. Even testing basic graphical user interfaces remains a challenge that has rarely been addressed in the field of software engineering [9]. However, the non reliability of interactive software can jeopardize usability evaluation by showing unexpected or undesired behaviors. The aim of this SIG is to provide a forum for both researchers and practitioners interested in testing interactive software. Our goal is to define a roadmap of activities to cross fertilize usability and reliability testing of these kinds of systems to minimize duplicate efforts in both communities.« less

Personalized reminiscence therapy M-health application for patients living with dementia: Innovating using open source code repository.

PubMed

Zhang, Melvyn W B; Ho, Roger C M

2017-01-01

Dementia is known to be an illness which brings forth marked disability amongst the elderly individuals. At times, patients living with dementia do also experience non-cognitive symptoms, and these symptoms include that of hallucinations, delusional beliefs as well as emotional liability, sexualized behaviours and aggression. According to the National Institute of Clinical Excellence (NICE) guidelines, non-pharmacological techniques are typically the first-line option prior to the consideration of adjuvant pharmacological options. Reminiscence and music therapy are thus viable options. Lazar et al. [3] previously performed a systematic review with regards to the utilization of technology to delivery reminiscence based therapy to individuals who are living with dementia and has highlighted that technology does have benefits in the delivery of reminiscence therapy. However, to date, there has been a paucity of M-health innovations in this area. In addition, most of the current innovations are not personalized for each of the person living with Dementia. Prior research has highlighted the utility for open source repository in bioinformatics study. The authors hoped to explain how they managed to tap upon and make use of open source repository in the development of a personalized M-health reminiscence therapy innovation for patients living with dementia. The availability of open source code repository has changed the way healthcare professionals and developers develop smartphone applications today. Conventionally, a long iterative process is needed in the development of native application, mainly because of the need for native programming and coding, especially so if the application needs to have interactive features or features that could be personalized. Such repository enables the rapid and cost effective development of application. Moreover, developers are also able to further innovate, as less time is spend in the iterative process.

Anatomic partial nephrectomy: technique evolution.

PubMed

Azhar, Raed A; Metcalfe, Charles; Gill, Inderbir S

2015-03-01

Partial nephrectomy provides equivalent long-term oncologic and superior functional outcomes as radical nephrectomy for T1a renal masses. Herein, we review the various vascular clamping techniques employed during minimally invasive partial nephrectomy, describe the evolution of our partial nephrectomy technique and provide an update on contemporary thinking about the impact of ischemia on renal function. Recently, partial nephrectomy surgical technique has shifted away from main artery clamping and towards minimizing/eliminating global renal ischemia during partial nephrectomy. Supported by high-fidelity three-dimensional imaging, novel anatomic-based partial nephrectomy techniques have recently been developed, wherein partial nephrectomy can now be performed with segmental, minimal or zero global ischemia to the renal remnant. Sequential innovations have included early unclamping, segmental clamping, super-selective clamping and now culminating in anatomic zero-ischemia surgery. By eliminating 'under-the-gun' time pressure of ischemia for the surgeon, these techniques allow an unhurried, tightly contoured tumour excision with point-specific sutured haemostasis. Recent data indicate that zero-ischemia partial nephrectomy may provide better functional outcomes by minimizing/eliminating global ischemia and preserving greater vascularized kidney volume. Contemporary partial nephrectomy includes a spectrum of surgical techniques ranging from conventional-clamped to novel zero-ischemia approaches. Technique selection should be tailored to each individual case on the basis of tumour characteristics, surgical feasibility, surgeon experience, patient demographics and baseline renal function.

Non-invasive, photonics-based diagnostic, imaging, monitoring, and light delivery techniques for the recognition, quantification and treatment of malignant and chronic inflammatory conditions

NASA Astrophysics Data System (ADS)

Davies, N.; Davies-Shaw, D.; Shaw, J. D.

2007-02-01

We report firsthand on innovative developments in non-invasive, biophotonic techniques for a wide range of diagnostic, imaging and treatment options, including the recognition and quantification of cancerous, pre-cancerous cells and chronic inflammatory conditions. These techniques have benefited from the ability to target the affected site by both monochromatic light and broad multiple wavelength spectra. The employment of such wavelength or color-specific properties embraces the fluorescence stimulation of various photosensitizing drugs, and the instigation and detection of identified fluorescence signatures attendant upon laser induced fluorescence (LIF) phenomena as transmitted and propagated by precancerous, cancerous and normal tissue. In terms of tumor imaging and therapeutic and treatment options, we have exploited the abilities of various wavelengths to penetrate to different depths, through different types of tissues, and have explored quantifiable absorption and reflection characteristics upon which diagnostic assumptions can be reliably based and formulated. These biophotonic-based diagnostic, sensing and imaging techniques have also benefited from, and have been further enhanced by, the integrated ability to provide various power levels to be employed at various stages in the procedure. Applications are myriad, including non-invasive, non destructive diagnosis of in vivo cell characteristics and functions; light-based tissue analysis; real-time monitoring and mapping of brain function and of tumor growth; real time monitoring of the surgical completeness of tumor removal during laser-imaged/guided brain resection; diagnostic procedures based on fluorescence life-time monitoring, the monitoring of chronic inflammatory conditions (including rheumatoid arthritis), and continuous blood glucose monitoring in the control of diabetes.

Mobile Aerial Tracking and Imaging System (MATRIS) for Aeronautical Research

NASA Technical Reports Server (NTRS)

Banks, Daniel W.; Blanchard, R. C.; Miller, G. M.

2004-01-01

A mobile, rapidly deployable ground-based system to track and image targets of aeronautical interest has been developed. Targets include reentering reusable launch vehicles (RLVs) as well as atmospheric and transatmospheric vehicles. The optics were designed to image targets in the visible and infrared wavelengths. To minimize acquisition cost and development time, the system uses commercially available hardware and software where possible. The conception and initial funding of this system originated with a study of ground-based imaging of global aerothermal characteristics of RLV configurations. During that study NASA teamed with the Missile Defense Agency/Innovative Science and Technology Experimentation Facility (MDA/ISTEF) to test techniques and analysis on two Space Shuttle flights.

The Lunar Transit Telescope (LTT) - An early lunar-based science and engineering mission

NASA Technical Reports Server (NTRS)

Mcgraw, John T.

1992-01-01

The Sentinel, the soft-landed lunar telescope of the LTT project, is described. The Sentinel is a two-meter telescope with virtually no moving parts which accomplishes an imaging survey of the sky over almost five octaves of the electromagnetic spectrum from the ultraviolet into the infrared, with an angular resolution better than 0.1 arsec/pixel. The Sentinel will incorporate innovative techniques of interest for future lunar-based telescopes and will return significant engineering data which can be incorporated into future lunar missions. The discussion covers thermal mapping of the Sentinel, measurement of the cosmic ray flux, lunar dust, micrometeoroid flux, the lunar atmosphere, and lunar regolith stability and seismic activity.

[Recent Development of Atomic Spectrometry in China].

PubMed

Xiao, Yuan-fang; Wang, Xiao-hua; Hang, Wei

2015-09-01

As an important part of modern analytical techniques, atomic spectrometry occupies a decisive status in the whole analytical field. The development of atomic spectrometry also reflects the continuous reform and innovation of analytical techniques. In the past fifteen years, atomic spectrometry has experienced rapid development and been applied widely in many fields in China. This review has witnessed its development and remarkable achievements. It contains several directions of atomic spectrometry, including atomic emission spectrometry (AES), atomic absorption spectrometry (AAS), atomic fluorescence spectrometry (AFS), X-ray fluorescence spectrometry (XRF), and atomic mass spectrometry (AMS). Emphasis is put on the innovation of the detection methods and their applications in related fields, including environmental samples, biological samples, food and beverage, and geological materials, etc. There is also a brief introduction to the hyphenated techniques utilized in atomic spectrometry. Finally, the prospects of atomic spectrometry in China have been forecasted.

Online marketing of food and beverages to children: a content analysis.

PubMed

Brady, Jennifer; Mendelson, Rena; Farrell, Amber; Wong, Sharon

2010-01-01

The goal was to assess websites sponsored by food and beverage manufacturers that have pledged to market branded food and beverage products to children responsibly, by ratifying the Children's Food and Beverage Advertising Initiative (CFBAI). A content analysis was conducted of 24 purposively sampled websites sponsored by 10 companies that promote food and beverage products to children. All are participant members of the CFBAI. Of the 24 websites analyzed, the majority targeted children below age 12 (83%). An array of innovative online marketing techniques, most notably free website membership (63%), leader boards (50%), adver-games (79%), and branded downloadable content (76%), were used to encourage children's engagement with branded food and beverage promotions. Food and beverage manufacturers are engaging children with dynamic online marketing techniques that challenge regulatory codes governing broadcast media. These techniques may contradict the spirit of the CFBAI. Innovative regulatory guidelines are needed to address modern marketing media.

Endoscopic Debridement for Treatment of Chronic Plantar Fasciitis: An Innovative Technique and Prospective Study of 46 Consecutive Patients.

PubMed

Cottom, James M; Maker, Jared M; Richardson, Phillip; Baker, Joseph S

2016-01-01

Plantar fasciitis is one the most common pathologies treated by foot and ankle surgeons. When nonoperative therapy fails, surgical intervention might be warranted. Various surgical procedures are available for the treatment of recalcitrant plantar fasciitis. The most common surgical management typically consists of open versus endoscopic plantar fascia release. Comorbidities associated with the release of the plantar fascia have been documented, including lateral column overload and metatarsalgia. We present an innovative technique for this painful condition that is minimally invasive, allows visualization of the plantar fascia, and maintains the integrity of the fascia. Our hypothesis was that the use of endoscopic debridement of the plantar fascia with or without heel spur resection would provide a minimally invasive technique with acceptable patient outcomes. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Children and youth with disabilities: innovative methods for single qualitative interviews.

PubMed

Teachman, Gail; Gibson, Barbara E

2013-02-01

There is a paucity of explicit literature outlining methods for single-interview studies with children, and almost none have focused on engaging children with disabilities. Drawing from a pilot study, we address these gaps by describing innovative techniques, strategies, and methods for engaging children and youth with disabilities in a single qualitative interview. In the study, we explored the beliefs, assumptions, and experiences of children and youth with cerebral palsy and their parents regarding the importance of walking. We describe three key aspects of our child-interview methodological approach: collaboration with parents, a toolkit of customizable interview techniques, and strategies to consider the power differential inherent in child-researcher interactions. Examples from our research illustrate what worked well and what was less successful. Researchers can optimize single interviews with children with disabilities by collaborating with family members and by preparing a toolkit of customizable interview techniques.

Interval MULTIMOORA method with target values of attributes based on interval distance and preference degree: biomaterials selection

NASA Astrophysics Data System (ADS)

Hafezalkotob, Arian; Hafezalkotob, Ashkan

2017-06-01

A target-based MADM method covers beneficial and non-beneficial attributes besides target values for some attributes. Such techniques are considered as the comprehensive forms of MADM approaches. Target-based MADM methods can also be used in traditional decision-making problems in which beneficial and non-beneficial attributes only exist. In many practical selection problems, some attributes have given target values. The values of decision matrix and target-based attributes can be provided as intervals in some of such problems. Some target-based decision-making methods have recently been developed; however, a research gap exists in the area of MADM techniques with target-based attributes under uncertainty of information. We extend the MULTIMOORA method for solving practical material selection problems in which material properties and their target values are given as interval numbers. We employ various concepts of interval computations to reduce degeneration of uncertain data. In this regard, we use interval arithmetic and introduce innovative formula for interval distance of interval numbers to create interval target-based normalization technique. Furthermore, we use a pairwise preference matrix based on the concept of degree of preference of interval numbers to calculate the maximum, minimum, and ranking of these numbers. Two decision-making problems regarding biomaterials selection of hip and knee prostheses are discussed. Preference degree-based ranking lists for subordinate parts of the extended MULTIMOORA method are generated by calculating the relative degrees of preference for the arranged assessment values of the biomaterials. The resultant rankings for the problem are compared with the outcomes of other target-based models in the literature.

Installed Base as a Facilitator for User-Driven Innovation: How Can User Innovation Challenge Existing Institutional Barriers?

PubMed Central

Andersen, Synnøve Thomassen; Jansen, Arild

2012-01-01

The paper addresses an ICT-based, user-driven innovation process in the health sector in rural areas in Norway. The empirical base is the introduction of a new model for psychiatric health provision. This model is supported by a technical solution based on mobile phones that is aimed to help the communication between professional health personnel and patients. This innovation was made possible through the use of standard mobile technology rather than more sophisticated systems. The users were heavily involved in the development work. Our analysis shows that by thinking simple and small-scale solutions, including to take the user's needs and premises as a point of departure rather than focusing on advanced technology, the implementation process was made possible. We show that by combining theory on information infrastructures, user-oriented system development, and innovation in a three-layered analytical framework, we can explain the interrelationship between technical, organizational, and health professional factors that made this innovation a success. PMID:23304134

e-Business Innovation: The Next Decade

NASA Astrophysics Data System (ADS)

Marca, David A.

Innovation is invention or application of technologies or theories that radically alters business and the economy. For many years, innovation and the economy have been locked in 80-year cycles, which might imply that innovation is an economic driver, and vice versa. Based on this, some forecast that innovation and the economy might decrease sharply due to several forces: a) decreasing economic growth, b) increasing demand for custom services, c) more entrepreneurial work environments, and d) urban and environmental degradation. Should such forecasts hold true, business may need to alter its offerings, operations and organization to survive. Such a scenario may also require applied e-Business innovation by combining existing internet, wireless, broadband, and video technologies. One possible result: flexible front offices integrated with efficient back offices. Such an e-Business could comprise: a) a customer-based and transaction-based organization, b) functions for adaptive offerings that anticipate need, c) highly responsive, real-time, operations having no inventory, and d) value-based front-end, and automated back-end, decision making.

Changing learning with new interactive and media-rich instruction environments: virtual labs case study report.

PubMed

Huang, Camillan

2003-01-01

Technology has created a new dimension for visual teaching and learning with web-delivered interactive media. The Virtual Labs Project has embraced this technology with instructional design and evaluation methodologies behind the simPHYSIO suite of simulation-based, online interactive teaching modules in physiology for the Stanford students. In addition, simPHYSIO provides the convenience of anytime web-access and a modular structure that allows for personalization and customization of the learning material. This innovative tool provides a solid delivery and pedagogical backbone that can be applied to developing an interactive simulation-based training tool for the use and management of the Picture Archiving and Communication System (PACS) image information system. The disparity in the knowledge between health and IT professionals can be bridged by providing convenient modular teaching tools to fill the gaps in knowledge. An innovative teaching method in the whole PACS is deemed necessary for its successful implementation and operation since it has become widely distributed with many interfaces, components, and customizations. This paper will discuss the techniques for developing an interactive-based teaching tool, a case study of its implementation, and a perspective for applying this approach to an online PACS training tool. Copyright 2002 Elsevier Science Ltd.

Kingfisher: a system for remote sensing image database management

NASA Astrophysics Data System (ADS)

Bruzzo, Michele; Giordano, Ferdinando; Dellepiane, Silvana G.

2003-04-01

At present retrieval methods in remote sensing image database are mainly based on spatial-temporal information. The increasing amount of images to be collected by the ground station of earth observing systems emphasizes the need for database management with intelligent data retrieval capabilities. The purpose of the proposed method is to realize a new content based retrieval system for remote sensing images database with an innovative search tool based on image similarity. This methodology is quite innovative for this application, at present many systems exist for photographic images, as for example QBIC and IKONA, but they are not able to extract and describe properly remote image content. The target database is set by an archive of images originated from an X-SAR sensor (spaceborne mission, 1994). The best content descriptors, mainly texture parameters, guarantees high retrieval performances and can be extracted without losses independently of image resolution. The latter property allows DBMS (Database Management System) to process low amount of information, as in the case of quick-look images, improving time performance and memory access without reducing retrieval accuracy. The matching technique has been designed to enable image management (database population and retrieval) independently of dimensions (width and height). Local and global content descriptors are compared, during retrieval phase, with the query image and results seem to be very encouraging.

Surface treatments for controlling corrosion rate of biodegradable Mg and Mg-based alloy implants

PubMed Central

Uddin, M S; Hall, Colin; Murphy, Peter

2015-01-01

Due to their excellent biodegradability characteristics, Mg and Mg-based alloys have become an emerging material in biomedical implants, notably for repair of bone as well as coronary arterial stents. However, the main problem with Mg-based alloys is their rapid corrosion in aggressive environments such as human bodily fluids. Previously, many approaches such as control of alloying materials, composition and surface treatments, have been attempted to regulate the corrosion rate. This article presents a comprehensive review of recent research focusing on surface treatment techniques utilised to control the corrosion rate and surface integrity of Mg-based alloys in both in vitro and in vivo environments. Surface treatments generally involve the controlled deposition of thin film coatings using various coating processes, and mechanical surfacing such as machining, deep rolling or low plasticity burnishing. The aim is to either make a protective thin layer of a material or to change the micro-structure and mechanical properties at the surface and sub-surface levels, which will prevent rapid corrosion and thus delay the degradation of the alloys. We have organised the review of past works on coatings by categorising the coatings into two classes—conversion and deposition coatings—while works on mechanical treatments are reviewed based on the tool-based processes which affect the sub-surface microstructure and mechanical properties of the material. Various types of coatings and their processing techniques under two classes of coating and mechanical treatment approaches have been analysed and discussed to investigate their impact on the corrosion performance, biomechanical integrity, biocompatibility and cell viability. Potential challenges and future directions in designing and developing the improved biodegradable Mg/Mg-based alloy implants were addressed and discussed. The literature reveals that no solutions are yet complete and hence new and innovative approaches are required to leverage the benefit of Mg-based alloys. Hybrid treatments combining innovative biomimetic coating and mechanical processing would be regarded as a potentially promising way to tackle the corrosion problem. Synergetic cutting-burnishing integrated with cryogenic cooling may be another encouraging approach in this regard. More studies focusing on rigorous testing, evaluation and characterisation are needed to assess the efficacy of the methods. PMID:27877829

History, Evolution, and Continuing Innovations of Intracranial Aneurysm Surgery.

PubMed

Lai, Leon T; O'Neill, Anthea H

2017-06-01

Evolution in the surgical treatment of intracranial aneurysms is driven by the need to refine and innovate. From an early application of the Hunterian carotid ligation to modern-day sophisticated aneurysm clip designs, progress has been made through dedication and technical maturation of cerebrovascular neurosurgeons to overcome challenges in their practices. The global expansion of endovascular services has challenged the existence of aneurysm surgery, changing the complexity of the aneurysm case mix and volume that are referred for surgical repair. Concepts of how to best treat intracranial aneurysms have evolved over generations and will continue to do so with further technological innovations. As with the evolution of any type of surgery, innovations frequently arise from the criticism of current techniques. Copyright © 2017 Elsevier Inc. All rights reserved.

Analysis of flood modeling through innovative geomatic methods

NASA Astrophysics Data System (ADS)

Zazo, Santiago; Molina, José-Luis; Rodríguez-Gonzálvez, Pablo

2015-05-01

A suitable assessment and management of the exposure level to natural flood risks necessarily requires an exhaustive knowledge of the terrain. This study, primarily aimed to evaluate flood risk, firstly assesses the suitability of an innovative technique, called Reduced Cost Aerial Precision Photogrammetry (RC-APP), based on a motorized technology ultra-light aircraft ULM (Ultra-Light Motor), together with the hybridization of reduced costs sensors, for the acquisition of geospatial information. Consequently, this research generates the RC-APP technique which is found to be a more accurate-precise, economical and less time consuming geomatic product. This technique is applied in river engineering for the geometric modeling and risk assessment to floods. Through the application of RC-APP, a high spatial resolution image (orthophoto of 2.5 cm), and a Digital Elevation Model (DEM) of 0.10 m mesh size and high density points (about 100 points/m2), with altimetric accuracy of -0.02 ± 0.03 m have been obtained. These products have provided a detailed knowledge of the terrain, afterward used for the hydraulic simulation which has allowed a better definition of the inundated area, with important implications for flood risk assessment and management. In this sense, it should be noted that the achieved spatial resolution of DEM is 0.10 m which is especially interesting and useful in hydraulic simulations through 2D software. According to the results, the developed methodology and technology allows for a more accurate riverbed representation, compared with other traditional techniques such as Light Detection and Ranging (LiDAR), with a Root-Mean-Square Error (RMSE ± 0.50 m). This comparison has revealed that RC-APP has one lower magnitude order of error than the LiDAR method. Consequently, this technique arises as an efficient and appropriate tool, especially in areas with high exposure to risk of flooding. In hydraulic terms, the degree of detail achieved in the 3D model, has allowed reaching a significant increase in the knowledge of hydraulic variables in natural waterways.

CNS drug development in Europe--past progress and future challenges.

PubMed

Nutt, David J; Attridge, Jim

2014-01-01

Despite enormous progress in defining, diagnosing and treating mental disorders, EU health systems face a mounting challenge in responding to 'unmet need'. Mental illnesses produce a societal burden that exceeds that for either cancers or cardiovascular conditions. Leveraging advances in science and medicine to make available new innovative medicines is a key component in responding to this challenge. The dominant paradigm has been, is and will continue to be, one of incremental progress. Better medicines for depression, anxiety and psychoses in the working age population would add great value to patients and improve labour productivity. But psychotropic medicines face exceptional challenges in demonstrating their added value, due to uncertainty in patient diagnosis, selecting treatments and ensuring adherence. Also, there are major difficulties in estimating costs. Advances in understanding brain processes, identifying biomarkers and neuro-imaging techniques promise far more effective 'diagnostic-therapeutic' treatments and improved patient outcomes in the future. Currently there are valuable incremental innovations in late development, which may well fail to recover their R&D costs, because of very low reimbursed prices. This will send a signal to innovators not to persist with product development in this area. Recently several leading companies have withdrawn from R&D in these mental disorders. This is a worrying development since building the capabilities to succeed in any disease sector takes many years and, once dismantled, they cannot easily be re-established. Three policy interventions could improve innovation incentives: Further 'push' incentives under i) and streamlining under ii) alone will not reverse the decline in investment incentives. An EU consensus, based upon an innovation model which encompasses the Research, Development and Market phases as a single cyclical process, which addresses the weak 'market pull incentives' under iii) is needed. There is a very real risk that without such an integrated approach to policy reforms, innovation in psychotropic medicines will become a 'desert' in the same way that it did for antibiotics in the 1990's. Copyright © 2013 Elsevier Inc. All rights reserved.

Design Features of Pedagogically-Sound Software in Mathematics.

ERIC Educational Resources Information Center

Haase, Howard; And Others

Weaknesses in educational software currently available in the domain of mathematics are discussed. A technique that was used for the design and production of mathematics software aimed at improving problem-solving skills which combines sound pedagogy and innovative programming is presented. To illustrate the design portion of this technique, a…

Multimodal Self-Management for Children: An Holistic Program for Teachers.

ERIC Educational Resources Information Center

O'Keefe, Edward J.

This paper describes an innovative program for teaching self-management to children in elementary and secondary schools. The background of techniques for teaching self-management is briefly reviewed, the application of self-management techniques is noted, deficits in self-management programs are considered, and Lazarus's multimodal model of…

Microwave and radiofrequency techniques for clinical hyperthermia.

PubMed Central

Cheung, A. Y.

1982-01-01

Biological and practical constraints on the use of clinical hyperthermia for the management of cancer are discussed. Commonly used electromagnetic techniques for producing clinical hyperthermia are reviewed and compared. Innovative engineering designs leading to the realization of an integrated, safe and reliable clinical hyperthermia system are also presented. PMID:6950753

Photographic Enlargement of Printed Music: Technique, Application, and Implications.

ERIC Educational Resources Information Center

Flynn, Pauline T.; Rich, A. Jeanette

1982-01-01

Addressed a need for enlargement of music when retirement home residents were deprived of a self-fulfillment opportunity from choir activities due to failing eyesight. A photographic process yielded the needed feasible large reproductions. Innovative application of this technique affords wide-ranging potential for positive benefit beyond music…

Participatory Data Collection Technique for Capturing Beginning Farmer Program Outcomes

ERIC Educational Resources Information Center

Eschbach, Cheryl L.; Sirrine, J. R.; Lizotte, Erin; Rothwell, N. L.

2016-01-01

This article describes an innovative evaluation plan we employed to capture outcomes of a multiyear beginning farmer program and, specifically, highlights the facilitation technique we used to document short-term and intermediate goals of the program that matched U.S. Department of Agriculture grant requirements and Extension administration…

Reward Industry for Innovative Outcomes

DTIC Science & Technology

2015-08-01

Defense AT&L: July–August 2015 34 Reward Industry for Innovative Outcomes RADM Allie Coetzee, USN Coetzee is Acting Director of Defense Procurement...away from the “best efforts” default and toward rational use of other techniques. Rather than reward compa- nies with contracts and funds to pursue...concepts advanced on paper in proposals, the DoD desires to reward companies that deliver demonstrable results through early prototypes that can be

Inaugural editorial: Military Medical Research.

PubMed

Ren, Guo-Quan

2014-01-01

Military medicine is one of the most innovative part of human civilization. Along with the rapid development of medicine and advances in military techniques, military medicine has become the focus and intersection of new knowledge and new technologies. Innovation and development within military medicine are always ongoing, with a long and challenging path ahead. The establishment of "Military Medical Research" is expected to be a bounden responsibility in the frontline of Chinese military medicine.

Probabilistic seasonal Forecasts to deterministic Farm Leve Decisions: Innovative Approach

NASA Astrophysics Data System (ADS)

Mwangi, M. W.

2015-12-01

Climate change and vulnerability are major challenges in ensuring household food security. Climate information services have the potential to cushion rural households from extreme climate risks. However, most the probabilistic nature of climate information products is not easily understood by majority of smallholder farmers. Despite the probabilistic nature, climate information have proved to be a valuable climate risk adaptation strategy at the farm level. This calls for innovative ways to help farmers understand and apply climate information services to inform their farm level decisions. The study endeavored to co-design and test appropriate innovation systems for climate information services uptake and scale up necessary for achieving climate risk development. In addition it also determined the conditions necessary to support the effective performance of the proposed innovation system. Data and information sources included systematic literature review, secondary sources, government statistics, focused group discussions, household surveys and semi-structured interviews. Data wasanalyzed using both quantitative and qualitative data analysis techniques. Quantitative data was analyzed using the Statistical Package for Social Sciences (SPSS) software. Qualitative data was analyzed using qualitative techniques, which involved establishing the categories and themes, relationships/patterns and conclusions in line with the study objectives. Sustainable livelihood, reduced household poverty and climate change resilience were the impact that resulted from the study.

Building the Capacity to Innovate: The Role of Human Capital. Research Report

ERIC Educational Resources Information Center

Smith, Andrew; Courvisanos, Jerry; Tuck, Jacqueline; McEachern, Steven

2012-01-01

This report examines the link between human resource management practices and innovation. It is based on a conceptual framework in which "human resource stimuli measures"--work organisation, working time, areas of training and creativity--feed into innovative capacity or innovation. Of course, having innovative capacity does not…

Cyberskepticism: The Mind’s Firewall

DTIC Science & Technology

2008-01-01

phonebook; BitTorrent; iTunes ; YouTube; forums; chat rooms; dating; Craig’s List; donate; blog/vlog; video games; e-invitations; e- cards ; weather...computer. Real-world romance techniques on the Internet have produced some very innovative cyber deception techniques. Valentine cards sent...electronically are one technique designed to enhance romance. In 2006 electronic Valentine cards were sent to unsuspecting people who opened them for various

Factors That Promote Innovativeness and Being an Innovative Learner at Work--Results from PIAAC

ERIC Educational Resources Information Center

Støren, Liv Anne

2016-01-01

In this article, innovative activity is considered in the light of broader conceptualisations of innovativeness and what it means to be innovative. Central to the definition of innovativeness used in the analysis is that the worker actively seeks new knowledge and uses it for work-related tasks. This is based on previous research emphasising…

Innovating Our Higher Education Models Based on Experience in UK and USA

ERIC Educational Resources Information Center

Hong, Jun; Chen, Haifeng

2008-01-01

Our higher education need to innovate education models and actively connect every member in big social system, for example, enterprises, society and environment. This paper shows some new ideas on innovating educational development based on author's studying experience in UK and in USA.

Healthcare in the age of open innovation - A literature review.

PubMed

Wass, Sofie; Vimarlund, Vivian

2016-12-01

In spite of an increased interest in open innovation and strategies that call for an increased collaboration between different healthcare actors, there is a lack of open innovation research in public contexts. This article presents the results of a review regarding the healthcare sector's engagement in open innovation as well as constraining factors and positive outcomes of open innovation in healthcare. The literature search focused on papers published in English between 2003 and 2014. Based on specified inclusion criteria, 18 articles were included. Results reveal that most studies focus on inbound open innovation where external knowledge is integrated with the internal knowledge base at an initial phase of the innovation process. Innovation primarily results in products and services through innovation networks. We also identified constraining factors for open innovation in healthcare, including the complex organizations of healthcare, the need to establish routines for capturing knowledge from patients and clinicians, regulations and healthcare data laws as well as the positive outcome patient empowerment. The healthcare sector's engagement in open innovation is limited, and it is necessary to perform further research with a focus on how open innovation can be managed in healthcare. © The Author(s) 2016.

Second-order spherical optoelectronic detector for 3D multi-particles wave emission and propagation in space time domains

NASA Astrophysics Data System (ADS)

Romano, Francesco; Cimmino, Rosario F.

2017-09-01

This paper concerns a feasibility study on a 2nd order spherical, or three-dimensional, angular momentum and linear momentum detector for photonic radiation applications. It has been developed in order to obtain a paraxial approximation of physical events observed under Coulomb gauge condition, which is essential to compute both the longitudinal and transverse rotational components of the observed 3-D vortex field, generally neglected by conventional detection systems under current usage. Since light and laser beams are neither full transversal or rotational phenomena, to measure directly and in the same time both the energy, mainly not-rotational, related to the relevant part of the linear momentum and the potential solenoidal energy (vortex), related to the angular momentum, 2nd order spherical, or 3-D, detector techniques are required. In addition, direct 2nd order measure techniques enable development of TEM + DEM [17] studies, therefore allowing for monochromatic complex wave detection with a paraxial accuracy in the relativistic time-space domain. Light and optic or Electromagnetic 2nd order 3-D AnM energy may usefully be used in tre-dimensional optical TEM, noTEM, DEM vortex or laser communications The paper illustrates an innovative quadratic order 3-D spherical model detector applied to directly measure a light source power spectrum and compares the performances of this innovative technique with those obtained with a traditional 1st order system. Results from a number of test experiments conducted in cooperation with INAF Observatories of ArcetriFlorence and Medicina-Bologna (Italy), and focused on telescopic observations of the inter-stellar electromagnetic radiations, are also summarized. The innovative quadratic-order spherical detector turns out to be optimal for optical and/or radio telescopes application, optical and optoelectronic sensors development and gravitational wave 2nd order detectors implementation. Although the proposed method is very innovative, it shows a very good adherence with results obtained with the conventional techniques in current usage.

Step-gate polysilicon nanowires field effect transistor compatible with CMOS technology for label-free DNA biosensor.

PubMed

Wenga, G; Jacques, E; Salaün, A-C; Rogel, R; Pichon, L; Geneste, F

2013-02-15

Currently, detection of DNA hybridization using fluorescence-based detection technique requires expensive optical systems and complex bioinformatics tools. Hence, the development of new low cost devices that enable direct and highly sensitive detection stimulates a lot of research efforts. Particularly, devices based on silicon nanowires are emerging as ultrasensitive electrical sensors for the direct detection of biological species thanks to their high surface to volume ratio. In this study, we propose innovative devices using step-gate polycrystalline silicon nanowire FET (poly-Si NW FETs), achieved with simple and low cost fabrication process, and used as ultrasensitive electronic sensor for DNA hybridization. The poly-SiNWs are synthesized using the sidewall spacer formation technique. The detailed fabrication procedure for a step-gate NWFET sensor is described in this paper. No-complementary and complementary DNA sequences were clearly discriminated and detection limit to 1 fM range is observed. This first result using this nano-device is promising for the development of low cost and ultrasensitive polysilicon nanowires based DNA sensors compatible with the CMOS technology. Copyright © 2012 Elsevier B.V. All rights reserved.

Research on TRIZ and CAIs Application Problems for Technology Innovation

NASA Astrophysics Data System (ADS)

Li, Xiangdong; Li, Qinghai; Bai, Zhonghang; Geng, Lixiao

In order to realize application of invent problem solve theory (TRIZ) and computer aided innovation software (CAIs) , need to solve some key problems, such as the mode choice of technology innovation, establishment of technology innovation organization network(TION), and achievement of innovative process based on TRIZ and CAIs, etc.. This paper shows that the demands for TRIZ and CAIs according to the characteristics and existing problem of the manufacturing enterprises. Have explained that the manufacturing enterprises need to set up an open TION of enterprise leading type, and achieve the longitudinal cooperation innovation with institution of higher learning. The process of technology innovation based on TRIZ and CAIs has been set up from researching and developing point of view. Application of TRIZ and CAIs in FY Company has been summarized. The application effect of TRIZ and CAIs has been explained using technology innovation of the close goggle valve product.

Leadership, Knowledge Sharing, and Creativity: The Key Factors in Nurses' Innovative Behaviors.

PubMed

Kim, Sung-Jin; Park, Myonghwa

2015-12-01

This study identified the factors that affect the innovative behaviors of nurses at general hospitals based on their individual and organizational characteristics. The predictors of innovative nursing behaviors, such as self-leadership, individual knowledge sharing, creative self-efficacy, organizational knowledge sharing, and innovative organizational cultures, should be explored at individual and organizational level. This study administered a cross-sectional survey to 347 registered nurses working at 6 general hospitals (with >300 beds) in central South Korea. Data were collected using a self-report questionnaire and analyzed using structural equation modeling. Self-leadership, creative self-efficacy, and individual knowledge sharing directly affected individual innovative behaviors. Organizational knowledge sharing indirectly affected individual innovative behaviors, and this effect was mediated by an innovative organizational culture. This study contributes to the knowledge base regarding the effective management of individuals and organizations through innovative behavior; furthermore, it provides future directions for nursing interventions.

Modeling the sustainable development of innovation in transport construction based on the communication approach

NASA Astrophysics Data System (ADS)

Revunova, Svetlana; Vlasenko, Vyacheslav; Bukreev, Anatoly

2017-10-01

The article proposes the models of innovative activity development, which is driven by the formation of “points of innovation-driven growth”. The models are based on the analysis of the current state and dynamics of innovative development of construction enterprises in the transport sector and take into account a number of essential organizational and economic changes in management. The authors substantiate implementing such development models as an organizational innovation that has a communication genesis. The use of the communication approach to the formation of “points of innovation-driven growth” allowed the authors to apply the mathematical tools of the graph theory in order to activate the innovative activity of the transport industry in the region. As a result, the authors have proposed models that allow constructing an optimal mechanism for the formation of “points of innovation-driven growth”.

X-ray Imaging and preliminary studies of the X-ray self-emission from an innovative plasma-trap based on the Bernstein waves heating mechanism

NASA Astrophysics Data System (ADS)

Caliri, C.; Romano, F. P.; Mascali, D.; Gammino, S.; Musumarra, A.; Castro, G.; Celona, L.; Neri, L.; Altana, C.

2013-10-01

Electron Cyclotron Resonance Ion Sources (ECRIS) are based on ECR heated plasmas emitting high fluxes of X-rays. Here we illustrate a pilot study of the X-ray emission from a compact plasma-trap in which an off-resonance microwave-plasma interaction has been attempted, highlighting a possible Bernstein-Waves based heating mechanism. EBWs-heating is obtained via the inner plasma EM-to-ES wave conversion and enables to reach densities much larger than the cut-off ones. At LNS-INFN, an innovative diagnostic technique based on the design of a Pinhole Camera (PHC) coupled to a CCD device for X-ray Imaging of the plasma (XRI) has been developed, in order to integrate X-ray traditional diagnostics (XRS). The complementary use of electrostatic probes measurements and X-ray diagnostics enabled us to gain knowledge about the high energy electrons density and temperature and about the spatial structure of the source. The combination of the experimental data with appropriate modeling of the plasma-source allowed to estimate the X-ray emission intensity in different energy domains (ranging from EUV up to Hard X-rays). The use of ECRIS as X-ray source for multidisciplinary applications, is now a concrete perspective due to the intense fluxes produced by the new plasma heating mechanism.

Mobile healthcare applications: system design review, critical issues and challenges.

PubMed

Baig, Mirza Mansoor; GholamHosseini, Hamid; Connolly, Martin J

2015-03-01

Mobile phones are becoming increasingly important in monitoring and delivery of healthcare interventions. They are often considered as pocket computers, due to their advanced computing features, enhanced preferences and diverse capabilities. Their sophisticated sensors and complex software applications make the mobile healthcare (m-health) based applications more feasible and innovative. In a number of scenarios user-friendliness, convenience and effectiveness of these systems have been acknowledged by both patients as well as healthcare providers. M-health technology employs advanced concepts and techniques from multidisciplinary fields of electrical engineering, computer science, biomedical engineering and medicine which benefit the innovations of these fields towards healthcare systems. This paper deals with two important aspects of current mobile phone based sensor applications in healthcare. Firstly, critical review of advanced applications such as; vital sign monitoring, blood glucose monitoring and in-built camera based smartphone sensor applications. Secondly, investigating challenges and critical issues related to the use of smartphones in healthcare including; reliability, efficiency, mobile phone platform variability, cost effectiveness, energy usage, user interface, quality of medical data, and security and privacy. It was found that the mobile based applications have been widely developed in recent years with fast growing deployment by healthcare professionals and patients. However, despite the advantages of smartphones in patient monitoring, education, and management there are some critical issues and challenges related to security and privacy of data, acceptability, reliability and cost that need to be addressed.

Observing hydrological processes: recent advancements in surface flow monitoring through image analysis

NASA Astrophysics Data System (ADS)

Tauro, Flavia; Grimaldi, Salvatore

2017-04-01

Recently, several efforts have been devoted to the design and development of innovative, and often unintended, approaches for the acquisition of hydrological data. Among such pioneering techniques, this presentation reports recent advancements towards the establishment of a novel noninvasive and potentially continuous methodology based on the acquisition and analysis of images for spatially distributed observations of the kinematics of surface waters. The approach aims at enabling rapid, affordable, and accurate surface flow monitoring of natural streams. Flow monitoring is an integral part of hydrological sciences and is essential for disaster risk reduction and the comprehension of natural phenomena. However, water processes are inherently complex to observe: they are characterized by multiscale and highly heterogeneous phenomena which have traditionally demanded sophisticated and costly measurement techniques. Challenges in the implementation of such techniques have also resulted in lack of hydrological data during extreme events, in difficult-to-access environments, and at high temporal resolution. By combining low-cost yet high-resolution images and several velocimetry algorithms, noninvasive flow monitoring has been successfully conducted at highly heterogeneous scales, spanning from rills to highly turbulent streams, and medium-scale rivers, with minimal supervision by external users. Noninvasive image data acquisition has also afforded observations in high flow conditions. Latest novelties towards continuous flow monitoring at the catchment scale have entailed the development of a remote gauge-cam station on the Tiber River and integration of flow monitoring through image analysis with unmanned aerial systems (UASs) technology. The gauge-cam station and the UAS platform both afford noninvasive image acquisition and calibration through an innovative laser-based setup. Compared to traditional point-based instrumentation, images allow for generating surface flow velocity maps which fully describe the kinematics of the velocity field in natural streams. Also, continuous observations provide a close picture of the evolving dynamics of natural water bodies. Despite such promising achievements, dealing with images also involves coping with adverse illumination, massive data handling and storage, and data-intensive computing. Most importantly, establishing a novel observational technique requires estimation of the uncertainty associated to measurements and thorough comparison to existing benchmark approaches. In this presentation, we provide answers to some of these issues and perspectives for future research.

Astronomical Near-neighbor Detection with a Four-quadrant Phase Mask (FQPM) Coronagraph

NASA Technical Reports Server (NTRS)

Haguenauer, Pierre; Serabyn, Eugene; Mennesson, Bertrand; Wallace, James K.; Gappinger, Robert O.; Troy, Mitchell; Bloemhof, Eric E.; Moore, Jim; Koresko, Chris D.

2006-01-01

Direct detection of planets around nearby stars requires the development of high-contrast imaging techniques, because of their very different respective fluxes. We thus investigated the innovative coronagraphic approach based on the use of a four-quadrant phase mask (FQPM). Simulations showed that, combined with high-level wavefront correction on an unobscured off-axis section of a large telescope, this method allows high-contrast imaging very close to stars, with detection capability superior to that of a traditional coronagraph. A FQPM instrument was thus built to test the feasibility of near-neighbor observations with our new off-axis approach on a ground-based telescope. In June 2005, we deployed our instrument to the Palomar 200-inch telescope, using existing facilities as much as possible for rapid implementation. In these initial observations, using data processing techniques specific to FQPM coronagraphs, we reached extinction levels of the order of 200:1. Here we discuss our simulations and on-sky results obtained so far.

Stochastic-field cavitation model

NASA Astrophysics Data System (ADS)

Dumond, J.; Magagnato, F.; Class, A.

2013-07-01

Nonlinear phenomena can often be well described using probability density functions (pdf) and pdf transport models. Traditionally, the simulation of pdf transport requires Monte-Carlo codes based on Lagrangian "particles" or prescribed pdf assumptions including binning techniques. Recently, in the field of combustion, a novel formulation called the stochastic-field method solving pdf transport based on Eulerian fields has been proposed which eliminates the necessity to mix Eulerian and Lagrangian techniques or prescribed pdf assumptions. In the present work, for the first time the stochastic-field method is applied to multi-phase flow and, in particular, to cavitating flow. To validate the proposed stochastic-field cavitation model, two applications are considered. First, sheet cavitation is simulated in a Venturi-type nozzle. The second application is an innovative fluidic diode which exhibits coolant flashing. Agreement with experimental results is obtained for both applications with a fixed set of model constants. The stochastic-field cavitation model captures the wide range of pdf shapes present at different locations.

BANNER: an executable survey of advances in biomedical named entity recognition.

PubMed

Leaman, Robert; Gonzalez, Graciela

2008-01-01

There has been an increasing amount of research on biomedical named entity recognition, the most basic text extraction problem, resulting in significant progress by different research teams around the world. This has created a need for a freely-available, open source system implementing the advances described in the literature. In this paper we present BANNER, an open-source, executable survey of advances in biomedical named entity recognition, intended to serve as a benchmark for the field. BANNER is implemented in Java as a machine-learning system based on conditional random fields and includes a wide survey of the best techniques recently described in the literature. It is designed to maximize domain independence by not employing brittle semantic features or rule-based processing steps, and achieves significantly better performance than existing baseline systems. It is therefore useful to developers as an extensible NER implementation, to researchers as a standard for comparing innovative techniques, and to biologists requiring the ability to find novel entities in large amounts of text.

Hyperspectral imaging as a technique for investigating the effect of consolidating materials on wood

NASA Astrophysics Data System (ADS)

Bonifazi, Giuseppe; Serranti, Silvia; Capobianco, Giuseppe; Agresti, Giorgia; Calienno, Luca; Picchio, Rodolfo; Lo Monaco, Angela; Santamaria, Ulderico; Pelosi, Claudia

2017-01-01

The focus of this study was to investigate the potential of hyperspectral imaging (HSI) in the monitoring of commercial consolidant products applied on wood samples. Poplar (Populus spp.) and walnut (Juglans Regia L.) were chosen for the consolidant application. Both traditional and innovative products were selected, based on acrylic, epoxy, and aliphatic compounds. Wood samples were stressed by freeze/thaw cycles in order to cause material degradation without the loss of wood components. Then the consolidant was applied under vacuum. The samples were finally artificially aged for 168 h in a solar box chamber. The samples were acquired in the short wave infrared (1000 to 2500 nm) range by SISUChema XL™ device (Specim, Finland) after 168 h of irradiation. As comparison, color measurement was also used as an economic, simple, and noninvasive technique to evaluate the deterioration and consolidation effects on wood. All data were then processed adopting a chemometric approach finalized to define correlation models, HSI based, between consolidating materials, wood species, and short-time aging effects.

Stochastic-field cavitation model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dumond, J., E-mail: julien.dumond@areva.com; AREVA GmbH, Erlangen, Paul-Gossen-Strasse 100, D-91052 Erlangen; Magagnato, F.

2013-07-15

Nonlinear phenomena can often be well described using probability density functions (pdf) and pdf transport models. Traditionally, the simulation of pdf transport requires Monte-Carlo codes based on Lagrangian “particles” or prescribed pdf assumptions including binning techniques. Recently, in the field of combustion, a novel formulation called the stochastic-field method solving pdf transport based on Eulerian fields has been proposed which eliminates the necessity to mix Eulerian and Lagrangian techniques or prescribed pdf assumptions. In the present work, for the first time the stochastic-field method is applied to multi-phase flow and, in particular, to cavitating flow. To validate the proposed stochastic-fieldmore » cavitation model, two applications are considered. First, sheet cavitation is simulated in a Venturi-type nozzle. The second application is an innovative fluidic diode which exhibits coolant flashing. Agreement with experimental results is obtained for both applications with a fixed set of model constants. The stochastic-field cavitation model captures the wide range of pdf shapes present at different locations.« less

Nonlinear ship waves and computational fluid dynamics

PubMed Central

MIYATA, Hideaki; ORIHARA, Hideo; SATO, Yohei

2014-01-01

Research works undertaken in the first author’s laboratory at the University of Tokyo over the past 30 years are highlighted. Finding of the occurrence of nonlinear waves (named Free-Surface Shock Waves) in the vicinity of a ship advancing at constant speed provided the start-line for the progress of innovative technologies in the ship hull-form design. Based on these findings, a multitude of the Computational Fluid Dynamic (CFD) techniques have been developed over this period, and are highlighted in this paper. The TUMMAC code has been developed for wave problems, based on a rectangular grid system, while the WISDAM code treats both wave and viscous flow problems in the framework of a boundary-fitted grid system. These two techniques are able to cope with almost all fluid dynamical problems relating to ships, including the resistance, ship’s motion and ride-comfort issues. Consequently, the two codes have contributed significantly to the progress in the technology of ship design, and now form an integral part of the ship-designing process. PMID:25311139

Media attention to GM food cases: An innovation perspective.

PubMed

Flipse, Steven M; Osseweijer, Patricia

2013-02-01

Media attention to genetically modified (GM) foods has been described as negative, especially in Europe. At the turn of the century appreciation of GM foods was at an all-time low in Europe. Food manufacturers are still careful in the use, development and communication of GM based food products, and their caution influences innovation processes. In this study we explore the link between media attention and innovation practice. Media attention to three specific high-profile GM food cases is described and linked to innovation practice. We elucidate the order of events in these cases and show that publics could only to a limited extent have formed an opinion on GM based food products based on scientifically valid data through written English media. Innovators in food biotechnology may benefit from this knowledge for future product development and marketing, and we suggest that innovation may benefit from early stakeholder involvement and communication activities.

Human pathogens, nosocomial infections, heat-sensitive textile implants, and an innovative approach to deal with them.

PubMed

Cinquemani, Claudio

2011-01-01

Implantable polymers, as used for biomedical applications, inherently have to be sterile. Nonetheless, most implants, particularly those comprised of biomaterials developed in recent years for tissue engineering, are heat sensitive. Therefore, use of hazardous (radio)chemicals--due to lack of alternative methods--is still state of the art for sterilization processes. The drawbacks of these techniques, both drastic and well known, lead to the demand for an alternative sterilization method, which is equally obvious and urgent. High-pressure fluid treatment is a low-temperature technique that is already in use for pasteurization of liquid food products. This paper explores inactivation of vegetative microorganisms, spores, and endotoxins adherent to solid surfaces using compressed CO(2). Pressures ranging from 50 to 100 bar and temperatures from 25 °C to 50 °C were explored to investigate liquid, gaseous or supercritical state. Analysis of variance (ANOVA) and statistical modeling were used to identify the optimum parameter settings for inactivation of pathogenic bacteria and fungi (Candida albicans, Staphylococcus aureus). The addition of small amounts of ozone ensures inactivation of persistent spores (Bacillus stearothermophilus, B. subtilis) up to 10(6) cfu/ml, while endotoxins remain in practically unchanged concentration on the polymer surface. We then discuss environmental issues of the process and inactivation mechanisms. The replacement of conventional chemicals with nonpersistent ones resolves organizational and safety-related issues and protects natural resources as well as handling staff. The pressurized-fluid-based method exhibits mild treatment parameters, thus protecting sensitive textures. Finally, an outlook on possible applications of this innovative technique is presented.

Microstructural characterization of catalysis product of nanocement based materials: A review

NASA Astrophysics Data System (ADS)

Sutan, Norsuzailina Mohamed; Izaitul Akma Ideris, Nur; Taib, Siti Noor Linda; Lee, Delsye Teo Ching; Hassan, Alsidqi; Kudnie Sahari, Siti; Mohamad Said, Khairul Anwar; Rahman Sobuz, Habibur

2018-03-01

Cement as an essential element for cement-based products contributed to negative environmental issues due to its high energy consumption and carbon dioxide emission during its production. These issues create the need to find alternative materials as partial cement replacement where studies on the potential of utilizing silica based materials as partial cement replacement come into picture. This review highlights the effectiveness of microstructural characterization techniques that have been used in the studies that focus on characterization of calcium hydroxide (CH) and calcium silicate hydrate (C-S-H) formation during hydration process of cement-based product incorporating nano reactive silica based materials as partial cement replacement. Understanding the effect of these materials as cement replacement in cement based product focusing on the microstructural development will lead to a higher confidence in the use of industrial waste as a new non-conventional material in construction industry that can catalyse rapid and innovative advances in green technology.

Original technique for penile girth augmentation through porcine dermal acellular grafts: results in a 69-patient series.

PubMed

Alei, Giovanni; Letizia, Piero; Ricottilli, Francesco; Simone, Pierfranco; Alei, Lavinia; Massoni, Francesco; Ricci, Serafino

2012-07-01

Although different techniques for augmentation phalloplasty have been reported in the medical literature, this issue is still highly controversial, and none of the proposed procedures has been unanimously approved. The aim of this study is to describe an innovative surgical technique for penile girth augmentation with porcine dermal acellular grafts, through a small transverse incision at the penile base, along the penopubic junction. Between 2000 and 2009, 104 patients were referred to our institution for penile enhancement. After a preoperative psychosexual consultation and a general medical assessment, 69 patients were deemed suitable good candidates for surgery. The average penis circumference was measured at the mid-length of the penis and was 8.1 cm (5.4-10.7 cm) and 10.8 cm (6.5-15.8 cm) during flaccidity and erection, respectively. All patients received penile augmentation with porcine dermal acellular grafts. Results evaluation of an innovative technique for penile girth augmentation through exogenous porcine grafts and small penobubic incision. Postoperative measurements were performed at 6 and 12 months. At the 1-year follow-up, the average penis circumference was 11.3 cm (8.2-13.2 cm, 3.1 cm mean increase) during flaccidity and 13.2 cm (8.8-14.5 cm, 2.4 cm mean increase) during erection. No major complications occurred in the series. Minor complications were resolved with conservative treatment within 3 weeks. Sexual activity was resumed from 1 to 2 months after surgery. The psychosexual impact of the operation was beneficial in the majority of cases. Penile girth enlargement with acellular dermal matrix grafts has several advantages over augmentation with autogenous dermis-fat grafts: the elimination of donor site morbidity and a significantly shorter operation time. With this approach, through a short dorsal incision at the base of the penis, the scar is concealed in a crease covered by pubic hair and thus hardly visible. © 2012 International Society for Sexual Medicine.

An exploration of tutors' experiences of facilitating problem-based learning. Part 1--an educational research methodology combining innovation and philosophical tradition.

PubMed

Haith-Cooper, Melanie

2003-01-01

The use of problem-based learning (PBL) in Health Professional curricula is becoming more wide spread. Although the way in which the tutor facilitates PBL can have a major impact on students' learning (Andrews and Jones 1996), the literature provides little consistency as to how the tutor can effectively facilitate PBL (Haith-Cooper 2000). It is therefore important to examine the facilitation role to promote effective learning through the use of PBL. This article is the first of two parts exploring a study that was undertaken to investigate tutors' experiences of facilitating PBL. This part focuses on the methodology and the combining of innovative processes with traditional philosophical traditions to develop a systematic educational research methodology. The study was undertaken respecting the philosophy of hermeneutic phenomenology but utilised alternative data collection and analysis technique. Video conferencing and e-mail were used in conjunction with more traditional processes to access a worldwide sample. This paper explores some of the issues that arose when undertaking such a study. The second article then focuses on exploring the findings of the study and their implications for the facilitation of PBL.

Competency-Based Faculty Development in Community-Engaged Scholarship: A Diffusion of Innovation Approach

ERIC Educational Resources Information Center

Jordan, Catherine; Doherty, William J.; Jones-Webb, Rhonda; Cook, Nancy; Dubrow, Gail; Mendenhall, Tai J.

2012-01-01

The authors utilized interviews, competency surveys, and document review to evaluate the effectiveness of a one-year, cohort-based faculty development pilot program, grounded in diffusion of innovations theory, and aimed at increasing competencies in community engagement and community-engaged scholarship. Five innovator participants designed the…

A New Direction for Technology-Based Economic Development: The Role of Innovation Intermediaries

ERIC Educational Resources Information Center

Bendis, Richard A.; Seline, Richard S.; Byler, Ethan J.

2008-01-01

Accelerating innovation to drive economic growth is the foremost goal for technology-based economic development organizations today. Realizing this goal through programmes is challenged by limited and outdated operating models. The authors outline their 21st Century Innovation Intermediary model, which pairs commercialization with regional…

Developing a Questionnaire to Measure Perceived Attributes of eHealth Innovations

ERIC Educational Resources Information Center

Atkinson, Nancy L.

2007-01-01

Objectives: To design a valid and reliable questionnaire to assess perceived attributes of technology-based health education innovations. Methods: College students in 12 personal health courses reviewed a prototype eHealth intervention using a 30-item instrument based upon diffusion theory's perceived attributes of an innovation. Results:…

Quantitative identification of riverine nitrogen from point, direct runoff and base flow sources.

PubMed

Huang, Hong; Zhang, Baifa; Lu, Jun

2014-01-01

We present a methodological example for quantifying the contributions of riverine total nitrogen (TN) from point, direct runoff and base flow sources by combining a recursive digital filter technique and statistical methods. First, we separated daily riverine flow into direct runoff and base flow using a recursive digital filter technique; then, a statistical model was established using daily simultaneous data for TN load, direct runoff rate, base flow rate, and temperature; and finally, the TN loading from direct runoff and base flow sources could be inversely estimated. As a case study, this approach was adopted to identify the TN source contributions in Changle River, eastern China. Results showed that, during 2005-2009, the total annual TN input to the river was 1,700.4±250.2 ton, and the contributions of point, direct runoff and base flow sources were 17.8±2.8%, 45.0±3.6%, and 37.2±3.9%, respectively. The innovation of the approach is that the nitrogen from direct runoff and base flow sources could be separately quantified. The approach is simple but detailed enough to take the major factors into account, providing an effective and reliable method for riverine nitrogen loading estimation and source apportionment.

Innovative Design and Performance Evaluation of Bionic Imprinting Toothed Wheel

PubMed Central

Wang, Xiaoyang; Tong, Jin; Stephen, Carr

2018-01-01

A highly efficient soil-burrowing dung beetle possesses an intricate outer contour curve on its foreleg end-tooth. This study was carried out based on evidence that this special outer contour curve has the potential of reducing soil penetration resistance and could enhance soil-burrowing efficiency. A toothed wheel is a typical agricultural implement for soil imprinting, to increase its working efficiency; the approach of the bionic geometrical structure was utilized to optimize the innovative shape of imprinting toothed wheel. Characteristics in the dung beetle's foreleg end-tooth were extracted and studied by the edge detection technique. Then, this special outer contour curve was modeled by a nine-order polynomial function and used for the innovative design of imprinting the tooth's cutting edge. Both the conventional and bionic teeth were manufactured, and traction tests in a soil bin were conducted. Taking required draft force and volume of imprinted microbasin as the evaluating indexes, operating efficiency and quality of different toothed wheels were compared and investigated. Results indicate that compared with the conventional toothed wheel, a bionic toothed wheel possesses a better forward resistance reduction property against soil and, meanwhile, can enhance the quality of soil imprinting by increasing the volume of the created micro-basin. PMID:29515651

Merging spatially variant physical process models under an optimized systems dynamics framework.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cain, William O.; Lowry, Thomas Stephen; Pierce, Suzanne A.

The complexity of water resource issues, its interconnectedness to other systems, and the involvement of competing stakeholders often overwhelm decision-makers and inhibit the creation of clear management strategies. While a range of modeling tools and procedures exist to address these problems, they tend to be case specific and generally emphasize either a quantitative and overly analytic approach or present a qualitative dialogue-based approach lacking the ability to fully explore consequences of different policy decisions. The integration of these two approaches is needed to drive toward final decisions and engender effective outcomes. Given these limitations, the Computer Assisted Dispute Resolution systemmore » (CADRe) was developed to aid in stakeholder inclusive resource planning. This modeling and negotiation system uniquely addresses resource concerns by developing a spatially varying system dynamics model as well as innovative global optimization search techniques to maximize outcomes from participatory dialogues. Ultimately, the core system architecture of CADRe also serves as the cornerstone upon which key scientific innovation and challenges can be addressed.« less

Designing the molecular future.

PubMed

Schneider, Gisbert

2012-01-01

Approximately 25 years ago the first computer applications were conceived for the purpose of automated 'de novo' drug design, prominent pioneering tools being ALADDIN, CAVEAT, GENOA, and DYLOMMS. Many of these early concepts were enabled by innovative techniques for ligand-receptor interaction modeling like GRID, MCSS, DOCK, and CoMFA, which still provide the theoretical framework for several more recently developed molecular design algorithms. After a first wave of software tools and groundbreaking applications in the 1990s--expressly GROW, GrowMol, LEGEND, and LUDI representing some of the key players--we are currently witnessing a renewed strong interest in this field. Innovative ideas for both receptor and ligand-based drug design have recently been published. We here provide a personal perspective on the evolution of de novo design, highlighting some of the historic achievements as well as possible future developments of this exciting field of research, which combines multiple scientific disciplines and is, like few other areas in chemistry, subject to continuous enthusiastic discussion and compassionate dispute.

Designing the molecular future

NASA Astrophysics Data System (ADS)

Schneider, Gisbert

2012-01-01

Approximately 25 years ago the first computer applications were conceived for the purpose of automated `de novo' drug design, prominent pioneering tools being ALADDIN, CAVEAT, GENOA, and DYLOMMS. Many of these early concepts were enabled by innovative techniques for ligand-receptor interaction modeling like GRID, MCSS, DOCK, and CoMFA, which still provide the theoretical framework for several more recently developed molecular design algorithms. After a first wave of software tools and groundbreaking applications in the 1990s—expressly GROW, GrowMol, LEGEND, and LUDI representing some of the key players—we are currently witnessing a renewed strong interest in this field. Innovative ideas for both receptor and ligand-based drug design have recently been published. We here provide a personal perspective on the evolution of de novo design, highlighting some of the historic achievements as well as possible future developments of this exciting field of research, which combines multiple scientific disciplines and is, like few other areas in chemistry, subject to continuous enthusiastic discussion and compassionate dispute.

Concepts for the translation of genome-based innovations into public health: a comprehensive overview.

PubMed

Syurina, Elena V; Schulte In den Bäumen, Tobias; Brand, Angela; Ambrosino, Elena; Feron, Frans Jm

2013-03-01

Recent vast and rapid development of genome-related sciences is followed by the development of different assessment techniques or attempts to adapt the existing ones. The aim of this article is to give an overview of existing concepts for the assessment and translation of innovations into healthcare, applying a descriptive analysis of their present use by public health specialists and policy makers. The international literature review identified eight concepts including Health Technology Assessment, analytic validity, clinical validity, clinical utility, ethical, legal and social implications, Public Health Wheel and others. This study gives an overview of these concepts (including the level of current use) applying a descriptive analysis of their present use by public health specialists and policy makers. Despite the heterogeneity of the analyzed concepts and difference in use in everyday healthcare practice, the cross-integration of these concepts is important in order to improve translation speed and quality. Finally, some recommendations are made regarding the most applicable translational concepts.

Understanding innovators' experiences of barriers and facilitators in implementation and diffusion of healthcare service innovations: a qualitative study

PubMed Central

2011-01-01

Background Healthcare service innovations are considered to play a pivotal role in improving organisational efficiency and responding effectively to healthcare needs. Nevertheless, healthcare organisations encounter major difficulties in sustaining and diffusing innovations, especially those which concern the organisation and delivery of healthcare services. The purpose of the present study was to explore how healthcare innovators of process-based initiatives perceived and made sense of factors that either facilitated or obstructed the innovation implementation and diffusion. Methods A qualitative study was designed. Fifteen primary and secondary healthcare organisations in the UK, which had received health service awards for successfully generating and implementing service innovations, were studied. In-depth, semi structured interviews were conducted with the organisational representatives who conceived and led the development process. The data were recorded, transcribed and thematically analysed. Results Four main themes were identified in the analysis of the data: the role of evidence, the function of inter-organisational partnerships, the influence of human-based resources, and the impact of contextual factors. "Hard" evidence operated as a proof of effectiveness, a means of dissemination and a pre-requisite for the initiation of innovation. Inter-organisational partnerships and people-based resources, such as champions, were considered an integral part of the process of developing, establishing and diffusing the innovations. Finally, contextual influences, both intra-organisational and extra-organisational were seen as critical in either impeding or facilitating innovators' efforts. Conclusions A range of factors of different combinations and co-occurrence were pointed out by the innovators as they were reflecting on their experiences of implementing, stabilising and diffusing novel service initiatives. Even though the innovations studied were of various contents and originated from diverse organisational contexts, innovators' accounts converged to the significant role of the evidential base of success, the inter-personal and inter-organisational networks, and the inner and outer context. The innovators, operating themselves as important champions and being often willing to lead constructive efforts of implementation to different contexts, can contribute to the promulgation and spread of the novelties significantly. PMID:22176739

Understanding innovators' experiences of barriers and facilitators in implementation and diffusion of healthcare service innovations: a qualitative study.

PubMed

Barnett, Julie; Vasileiou, Konstantina; Djemil, Fayika; Brooks, Laurence; Young, Terry

2011-12-16

Healthcare service innovations are considered to play a pivotal role in improving organisational efficiency and responding effectively to healthcare needs. Nevertheless, healthcare organisations encounter major difficulties in sustaining and diffusing innovations, especially those which concern the organisation and delivery of healthcare services. The purpose of the present study was to explore how healthcare innovators of process-based initiatives perceived and made sense of factors that either facilitated or obstructed the innovation implementation and diffusion. A qualitative study was designed. Fifteen primary and secondary healthcare organisations in the UK, which had received health service awards for successfully generating and implementing service innovations, were studied. In-depth, semi structured interviews were conducted with the organisational representatives who conceived and led the development process. The data were recorded, transcribed and thematically analysed. Four main themes were identified in the analysis of the data: the role of evidence, the function of inter-organisational partnerships, the influence of human-based resources, and the impact of contextual factors. "Hard" evidence operated as a proof of effectiveness, a means of dissemination and a pre-requisite for the initiation of innovation. Inter-organisational partnerships and people-based resources, such as champions, were considered an integral part of the process of developing, establishing and diffusing the innovations. Finally, contextual influences, both intra-organisational and extra-organisational were seen as critical in either impeding or facilitating innovators' efforts. A range of factors of different combinations and co-occurrence were pointed out by the innovators as they were reflecting on their experiences of implementing, stabilising and diffusing novel service initiatives. Even though the innovations studied were of various contents and originated from diverse organisational contexts, innovators' accounts converged to the significant role of the evidential base of success, the inter-personal and inter-organisational networks, and the inner and outer context. The innovators, operating themselves as important champions and being often willing to lead constructive efforts of implementation to different contexts, can contribute to the promulgation and spread of the novelties significantly.

Shaping innovation in health care: A content analysis of innovation policies in the English NHS, 1948-2015.

PubMed

Farchi, Tomas; Salge, Torsten-Oliver

2017-11-01

Governments around the world seek to design policies that enhance the innovative capacity of public service. Hence, identifying the underlying meanings attributed to innovation concepts in public policies is critical, as these very understandings inform not only the policy discourses, but also the overall institutional landscape regulating innovation activities. This paper examines such fundamental definitional aspects in the specific context of the National Health Service in England. For this purpose, it traces the evolution of the innovation concept in policy discourse based on the analysis of 21 key policy documents published or commissioned by the English Department of Health between 1948 and 2015. Systematic analysis of these texts reveals that policymakers' conception of healthcare innovation broadened considerably over time. English health innovation policy initially focused on basic biomedical research. Subsequently, it entered a transitional period, zeroing in on science- and technology-based innovation. Finally, this focus gradually shifted to a broader conception of innovation translating into health, economic, and service design benefits. Copyright © 2017 Elsevier Ltd. All rights reserved.

Review on microfluidic paper-based analytical devices towards commercialisation.

PubMed

Akyazi, Tugce; Basabe-Desmonts, Lourdes; Benito-Lopez, Fernando

2018-02-25

Paper-based analytical devices introduce an innovative platform technology for fluid handling and analysis, with wide range of applications, promoting low cost, ease of fabrication/operation and equipment independence. This review gives a general overview on the fabrication techniques reported to date, revealing and discussing their weak points as well as the newest approaches in order to overtake current mass production limitations and therefore commercialisation. Moreover, this review aims especially to highlight novel technologies appearing in literature for the effective handling and controlling of fluids. The lack of flow control is the main problem of paper-based analytical devices, which generates obstacles for marketing and slows down the transition of paper devices from the laboratory into the consumers' hands. Copyright © 2017 Elsevier B.V. All rights reserved.

Studying with the cloud: the use of online Web-based resources to augment a traditional study group format.

PubMed

Chan, Teresa; Sennik, Serena; Zaki, Amna; Trotter, Brendon

2015-03-01

Cloud-based applications such as Google Docs, Skype, Dropbox, and SugarSync are revolutionizing the way that we interact with the world. Members of the millennial generation (those born after 1980) are now becoming senior residents and junior attending physicians. We describe a novel technique combining Internet- and cloud-based methods to digitally augment the classic study group used by final-year residents studying for the Royal College of Physicians and Surgeons of Canada examination. This material was developed by residents and improved over the course of 18 months. This is an innovation report about a process for enhanced communication and collaboration as there has been little research to date regarding the augmentation of learner-driven initiatives with virtual resources.

Cognitive approaches for patterns analysis and security applications

NASA Astrophysics Data System (ADS)

Ogiela, Marek R.; Ogiela, Lidia

2017-08-01

In this paper will be presented new opportunities for developing innovative solutions for semantic pattern classification and visual cryptography, which will base on cognitive and bio-inspired approaches. Such techniques can be used for evaluation of the meaning of analyzed patterns or encrypted information, and allow to involve such meaning into the classification task or encryption process. It also allows using some crypto-biometric solutions to extend personalized cryptography methodologies based on visual pattern analysis. In particular application of cognitive information systems for semantic analysis of different patterns will be presented, and also a novel application of such systems for visual secret sharing will be described. Visual shares for divided information can be created based on threshold procedure, which may be dependent on personal abilities to recognize some image details visible on divided images.

Analytical reverse time migration: An innovation in imaging of infrastructures using ultrasonic shear waves.

PubMed

Asadollahi, Aziz; Khazanovich, Lev

2018-04-11

The emergence of ultrasonic dry point contact (DPC) transducers that emit horizontal shear waves has enabled efficient collection of high-quality data in the context of a nondestructive evaluation of concrete structures. This offers an opportunity to improve the quality of evaluation by adapting advanced imaging techniques. Reverse time migration (RTM) is a simulation-based reconstruction technique that offers advantages over conventional methods, such as the synthetic aperture focusing technique. RTM is capable of imaging boundaries and interfaces with steep slopes and the bottom boundaries of inclusions and defects. However, this imaging technique requires a massive amount of memory and its computation cost is high. In this study, both bottlenecks of the RTM are resolved when shear transducers are used for data acquisition. An analytical approach was developed to obtain the source and receiver wavefields needed for imaging using reverse time migration. It is shown that the proposed analytical approach not only eliminates the high memory demand, but also drastically reduces the computation time from days to minutes. Copyright © 2018 Elsevier B.V. All rights reserved.

A Secret 3D Model Sharing Scheme with Reversible Data Hiding Based on Space Subdivision

NASA Astrophysics Data System (ADS)

Tsai, Yuan-Yu

2016-03-01

Secret sharing is a highly relevant research field, and its application to 2D images has been thoroughly studied. However, secret sharing schemes have not kept pace with the advances of 3D models. With the rapid development of 3D multimedia techniques, extending the application of secret sharing schemes to 3D models has become necessary. In this study, an innovative secret 3D model sharing scheme for point geometries based on space subdivision is proposed. Each point in the secret point geometry is first encoded into a series of integer values that fall within [0, p - 1], where p is a predefined prime number. The share values are derived by substituting the specified integer values for all coefficients of the sharing polynomial. The surface reconstruction and the sampling concepts are then integrated to derive a cover model with sufficient model complexity for each participant. Finally, each participant has a separate 3D stego model with embedded share values. Experimental results show that the proposed technique supports reversible data hiding and the share values have higher levels of privacy and improved robustness. This technique is simple and has proven to be a feasible secret 3D model sharing scheme.

Flow visualization over a thick blunt trailing-edge airfoil with base cavity at low Reynolds numbers using PIV technique.

PubMed

Taherian, Gholamhossein; Nili-Ahmadabadi, Mahdi; Karimi, Mohammad Hassan; Tavakoli, Mohammad Reza

2017-01-01

In this study, the effect of cutting the end of a thick airfoil and adding a cavity on its flow pattern is studied experimentally using PIV technique. First, by cutting 30% chord length of the Riso airfoil, a thick blunt trialing-edge airfoil is generated. The velocity field around the original airfoil and the new airfoil is measured by PIV technique and compared with each other. Then, adding two parallel plates to the end of the new airfoil forms the desired cavity. Continuous measurement of unsteady flow velocity over the Riso airfoil with thick blunt trailing edge and base cavity is the most important innovation of this research. The results show that cutting off the end of the airfoil decreases the wake region behind the airfoil, when separation occurs. Moreover, adding a cavity to the end of the thickened airfoil causes an increase in momentum and a further decrease in the wake behind the trailing edge that leads to a drag reduction in comparison with the thickened airfoil without cavity. Furthermore, using cavity decreases the Strouhal number and vortex shedding frequency.

[Theoretical and methodological uses of research in Social and Human Sciences in Health].

PubMed

Deslandes, Suely Ferreira; Iriart, Jorge Alberto Bernstein

2012-12-01

The current article aims to map and critically reflect on the current theoretical and methodological uses of research in the subfield of social and human sciences in health. A convenience sample was used to select three Brazilian public health journals. Based on a reading of 1,128 abstracts published from 2009 to 2010, 266 articles were selected that presented the empirical base of research stemming from social and human sciences in health. The sample was classified thematically as "theoretical/ methodological reference", "study type/ methodological design", "analytical categories", "data production techniques", and "analytical procedures". We analyze the sample's emic categories, drawing on the authors' literal statements. All the classifications and respective variables were tabulated in Excel. Most of the articles were self-described as qualitative and used more than one data production technique. There was a wide variety of theoretical references, in contrast with the almost total predominance of a single type of data analysis (content analysis). In several cases, important gaps were identified in expounding the study methodology and instrumental use of the qualitative research techniques and methods. However, the review did highlight some new objects of study and innovations in theoretical and methodological approaches.

Anaesthetic considerations for pectus repair surgery

PubMed Central

Patvardhan, Chinmay

2016-01-01

Repair of pectus is one of the most common congenital abnormality for which patient presents for thoracic surgery. In recent years, innovative minimally invasive techniques involving video assisted thoracoscopy for pectus repair have become the norm. Similarly, anaesthetic techniques have evolved to include principles of enhanced recovery, multimodal analgesia and innovative ultrasound guided neuraxial and nerve blocks. Adequate anaesthetic set up and monitoring including the use of real time intraoperative monitoring with transesophageal echocardiography (TOE) has enabled the anaesthetist to enhance patient safety by providing instantaneous imaging of cardiac compression and complications during surgery. In this review article we aim to provide non-systematic review and institutional experience of our anaesthetic strategy to provide effective peri-operative care in this patient group. PMID:29078504

A step-by-step guide to office-based sperm retrieval for obstructive azoospermia

PubMed Central

Mills, Jesse N.

2017-01-01

A variety of surgical options exists for sperm retrieval in the setting of obstructive azoospermia (OA). With appropriate preparation, the majority of these techniques can safely be performed in the office with local anesthesia and with or without monitored anesthesia care (MAC). The available techniques include percutaneous options such as percutaneous epididymal sperm aspiration (PESA) and testicular sperm aspiration (TESA), as well as open techniques that include testicular sperm extraction (TESE) and microsurgical epididymal sperm aspiration (MESA). In addition to providing a step-by-step description of each available approach, we introduce and describe a new technique for sperm retrieval for OA called minimally invasive epididymal sperm aspiration (MIESA). The MIESA utilizes a tiny keyhole incision, and the epididymis is exposed without testicular delivery. Epididymal aspiration is performed in the style of MESA, except using loupe magnification rather than an operating microscope. MIESA is a safe, office-based procedure in which millions of motile sperm can be retrieved for cryopreservation. While we prefer the MIESA technique for OA, there remain distinct advantages of each open and percutaneous approach. In the current era of assisted reproductive technology, sperm retrieval rates for OA should approach 100% regardless of the technique. This reference provides a roadmap for both advanced and novice male reproductive surgeons to guide them through every stage of sperm retrieval for OA, including preoperative evaluation, patient selection, procedural techniques, and complications. With the incredible advances in in vitro fertilization (IVF), combined with innovative surgical treatment for male factor infertility in recent years, OA is no longer a barrier for men to become biologic fathers. PMID:28904906

Building America Top Innovations 2014 Profile: Cost-Optimized Attic Insulation Solution for Factory-Built Homes

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

This 2014 Top Innovation profile describes a low-cost, low-tech attic insulation technique developed by the ARIES Building America team with help from Southern Energy Homes and Johns Manville. Increasing attic insulation in manufactured housing has been a significant challenge due to cost, production and transportation constraints. The simplicity of this dense-pack solution to increasing attic insulation R-value promises real hope for widespread industry adoption.

Native Advertising: Trickery or Technique? An Ethics Project and Debate

ERIC Educational Resources Information Center

Zarzosa, Jennifer; Fischbach, Sarah

2017-01-01

Sponsored content, in-feed ads, and advertorials are innovative ways to promote brands. However, there are limited resources on how to use these advertising techniques. The Native Advertising project and debate helps students (a) gain knowledge and experience with current advertising practices and (b) engage in deliberation regarding a promotional…

INNOVATIVE APPROACH FOR MEASURING AMMONIA AND METHANE FLUXES FROM A HOG FARM USING OPEN-PATH FOURIER TRANSFORM INFRARED SPECTROSCOPY

EPA Science Inventory

The paper describes a new approach to quantify emissions from area air pollution sources. The approach combines path-integrated concentration data acquired with any path-integrated optical remote sensing (PI-ORS) technique and computed tomography (CT) technique. In this study, an...

Adding to Your Teaching Repertoire: Integrating Action Research into the Lesson Plans

ERIC Educational Resources Information Center

Basham, Matthew J.; Yankowy, Barbara

2015-01-01

As today's students become more technologically savvy, social, and collaborative using social media, there are new and innovative techniques educators can use in the classroom. For example, action research is a newer technique using collaborative group processes, drawing upon the experiences of the individuals to promote positive results. This…

[Technical advances in haemodialysis].

PubMed

Mercadal, Lucile; Petitclerc, Thierry

2009-04-01

Survival improvement of our haemodialysis patients is partly due to technologic improvement of the dialysis therapy. High permeability membranes and bicarbonate dialysate were the most relevant of past decades. What are the present technologic innovations that will provide clinical benefit? Acetate-free biofiltration, biofeedback systems, better haemodiafiltration techniques and techniques with adsorption could be part of them.

Underwater Photogrammetry, Coded Target and Plenoptic Technology: a Set of Tools for Monitoring Red Coral in Mediterranean Sea in the Framework of the "perfect" Project

NASA Astrophysics Data System (ADS)

Drap, P.; Royer, J. P.; Nawaf, M. M.; Saccone, M.; Merad, D.; López-Sanz, À.; Ledoux, J. B.; Garrabou, J.

2017-02-01

PErfECT "Photogrammetry, gEnetic, Ecology for red coral ConservaTion" is a project leaded by the Laboratoire des Sciences de lInformation et des Systmes (LSIS - UMR 7296 CNRS) from the Aix-Marseille University (France) in collaboration with the Spanish National Agency for Scientific Research (CSIC, Spain). The main objective of the project is to develop innovative Tools for the conservation of the Mediterranean red coral, Corallium rubrum. PErfECT was funded by the Total Fundation. The adaptation of digital photogrammetric techniques for use in submarine is rapidly increasing in recent years. In fact, these techniques are particularly well suited for use in underwater environments. PErfECT developed different photogrammetry tools to enhance the red coral population surveys based in: (i) automatic orientation on coded quadrats, (ii) use of NPR (Non Photo realistic Rendering) techniques, (iii) the calculation of distances between colonies within local populations and finally (iv) the use of plenoptic approaches in underwater conditions.

Portable Infrared Laser Spectroscopy for On-site Mycotoxin Analysis.

PubMed

Sieger, Markus; Kos, Gregor; Sulyok, Michael; Godejohann, Matthias; Krska, Rudolf; Mizaikoff, Boris

2017-03-09

Mycotoxins are toxic secondary metabolites of fungi that spoil food, and severely impact human health (e.g., causing cancer). Therefore, the rapid determination of mycotoxin contamination including deoxynivalenol and aflatoxin B 1 in food and feed samples is of prime interest for commodity importers and processors. While chromatography-based techniques are well established in laboratory environments, only very few (i.e., mostly immunochemical) techniques exist enabling direct on-site analysis for traders and manufacturers. In this study, we present MYCOSPEC - an innovative approach for spectroscopic mycotoxin contamination analysis at EU regulatory limits for the first time utilizing mid-infrared tunable quantum cascade laser (QCL) spectroscopy. This analysis technique facilitates on-site mycotoxin analysis by combining QCL technology with GaAs/AlGaAs thin-film waveguides. Multivariate data mining strategies (i.e., principal component analysis) enabled the classification of deoxynivalenol-contaminated maize and wheat samples, and of aflatoxin B 1 affected peanuts at EU regulatory limits of 1250 μg kg -1 and 8 μg kg -1 , respectively.

Portable Infrared Laser Spectroscopy for On-site Mycotoxin Analysis

PubMed Central

Sieger, Markus; Kos, Gregor; Sulyok, Michael; Godejohann, Matthias; Krska, Rudolf; Mizaikoff, Boris

2017-01-01

Mycotoxins are toxic secondary metabolites of fungi that spoil food, and severely impact human health (e.g., causing cancer). Therefore, the rapid determination of mycotoxin contamination including deoxynivalenol and aflatoxin B1 in food and feed samples is of prime interest for commodity importers and processors. While chromatography-based techniques are well established in laboratory environments, only very few (i.e., mostly immunochemical) techniques exist enabling direct on-site analysis for traders and manufacturers. In this study, we present MYCOSPEC - an innovative approach for spectroscopic mycotoxin contamination analysis at EU regulatory limits for the first time utilizing mid-infrared tunable quantum cascade laser (QCL) spectroscopy. This analysis technique facilitates on-site mycotoxin analysis by combining QCL technology with GaAs/AlGaAs thin-film waveguides. Multivariate data mining strategies (i.e., principal component analysis) enabled the classification of deoxynivalenol-contaminated maize and wheat samples, and of aflatoxin B1 affected peanuts at EU regulatory limits of 1250 μg kg−1 and 8 μg kg−1, respectively. PMID:28276454

An innovative technique for the investigation of the 4-fold forbidden beta-decay of 50V

NASA Astrophysics Data System (ADS)

Pattavina, L.; Laubenstein, M.; Nagorny, S. S.; Nisi, S.; Pagnanini, L.; Pirro, S.; Rusconi, C.; Schäffner, K.

2018-05-01

For the first time a Vanadium-based crystal was operated as cryogenic particle detector. The scintillating low temperature calorimetric technique was used for the characterization of a 22g YVO4 crystal aiming at the investigation of the 4-fold forbidden non-unique β- decay of 50V. The excellent bolometric performance of the compound together with high light output of the crystal make it an outstanding technique for the study of such elusive rate process. The internal radioactive contaminations of the crystal are also investigated showing that an improvement on the current status of material selection and purification are needed, 235/238U and 232Th are measured at the level of 28mBq/kg, 1.3 Bq/kg and 28m Bq/kg, respectively. In this work, we also discuss a future upgrade of the experimental set-up which may pave the road for the detection of the rare 50V β- decay.

Fabrication of a Dipole-assisted Solid Phase Extraction Microchip for Trace Metal Analysis in Water Samples

PubMed Central

Chen, Ping-Hung; Chen, Shun-Niang; Tseng, Sheng-Hao; Deng, Ming-Jay; Lin, Yang-Wei; Sun, Yuh-Chang

2016-01-01

This paper describes a fabrication protocol for a dipole-assisted solid phase extraction (SPE) microchip available for trace metal analysis in water samples. A brief overview of the evolution of chip-based SPE techniques is provided. This is followed by an introduction to specific polymeric materials and their role in SPE. To develop an innovative dipole-assisted SPE technique, a chlorine (Cl)-containing SPE functionality was implanted into a poly(methyl methacrylate) (PMMA) microchip. Herein, diverse analytical techniques including contact angle analysis, Raman spectroscopic analysis, and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis were employed to validate the utility of the implantation protocol of the C-Cl moieties on the PMMA. The analytical results of the X-ray absorption near-edge structure (XANES) analysis also demonstrated the feasibility of the Cl-containing PMMA used as an extraction medium by virtue of the dipole-ion interactions between the highly electronegative C-Cl moieties and the positively charged metal ions. PMID:27584954

Portable Infrared Laser Spectroscopy for On-site Mycotoxin Analysis

NASA Astrophysics Data System (ADS)

Sieger, Markus; Kos, Gregor; Sulyok, Michael; Godejohann, Matthias; Krska, Rudolf; Mizaikoff, Boris

2017-03-01

Mycotoxins are toxic secondary metabolites of fungi that spoil food, and severely impact human health (e.g., causing cancer). Therefore, the rapid determination of mycotoxin contamination including deoxynivalenol and aflatoxin B1 in food and feed samples is of prime interest for commodity importers and processors. While chromatography-based techniques are well established in laboratory environments, only very few (i.e., mostly immunochemical) techniques exist enabling direct on-site analysis for traders and manufacturers. In this study, we present MYCOSPEC - an innovative approach for spectroscopic mycotoxin contamination analysis at EU regulatory limits for the first time utilizing mid-infrared tunable quantum cascade laser (QCL) spectroscopy. This analysis technique facilitates on-site mycotoxin analysis by combining QCL technology with GaAs/AlGaAs thin-film waveguides. Multivariate data mining strategies (i.e., principal component analysis) enabled the classification of deoxynivalenol-contaminated maize and wheat samples, and of aflatoxin B1 affected peanuts at EU regulatory limits of 1250 μg kg-1 and 8 μg kg-1, respectively.